# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Pkinase PF00069.20 EGD92423.1 - 3.3e-12 46.0 0.0 8.5e-12 44.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92423.1 - 2.6e-08 33.2 0.0 5e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EGD92423.1 - 0.00032 20.3 0.0 0.00077 19.0 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EGD92423.1 - 0.00085 19.1 0.1 0.018 14.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family SpoVAD PF07451.6 EGD92423.1 - 0.14 10.6 0.2 0.37 9.1 0.1 1.6 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) APC_CDC26 PF10471.4 EGD92425.1 - 0.073 13.8 0.4 1.3 9.8 0.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 GTP_cyclohydro2 PF00925.15 EGD92426.1 - 6.2e-57 191.5 0.0 1.5e-51 174.0 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II DUF1325 PF07039.6 EGD92427.1 - 8.9e-30 102.9 0.0 1.7e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.5 EGD92427.1 - 0.087 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain MS_channel PF00924.13 EGD92427.1 - 0.19 11.0 0.1 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel PMI_typeI PF01238.16 EGD92428.1 - 7.5e-148 492.4 0.0 9e-148 492.1 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 EGD92428.1 - 0.019 14.6 0.0 3 7.5 0.0 2.6 2 0 0 2 2 2 0 AraC-like ligand binding domain Abhydrolase_3 PF07859.8 EGD92429.1 - 3.4e-25 88.8 0.0 8.6e-25 87.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGD92429.1 - 1e-23 83.6 0.0 1.2e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGD92429.1 - 1.4e-05 24.8 0.1 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGD92429.1 - 0.0019 17.4 0.0 0.18 10.9 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EGD92429.1 - 0.023 14.1 0.0 1.1 8.6 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2974 PF11187.3 EGD92429.1 - 0.067 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Coatomer_E PF04733.9 EGD92430.1 - 3.4e-65 220.1 6.8 3.9e-65 219.9 4.7 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EGD92430.1 - 1.9e-07 31.3 24.4 0.00054 20.2 1.9 4.7 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGD92430.1 - 5.9e-06 26.7 23.5 0.00023 21.7 0.1 4.9 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD92430.1 - 8.4e-06 25.9 21.9 0.00057 20.2 0.1 5.5 4 1 2 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD92430.1 - 2.8e-05 24.1 6.3 0.034 14.2 1.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EGD92430.1 - 0.0049 16.4 5.3 0.044 13.4 0.0 3.8 3 1 0 3 3 3 1 TPR repeat Peptidase_S11 PF00768.15 EGD92430.1 - 0.016 14.5 0.2 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DUF627 PF04781.7 EGD92430.1 - 0.021 14.4 0.2 0.047 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF627) TPR_6 PF13174.1 EGD92430.1 - 0.027 14.9 7.3 0.28 11.7 0.0 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGD92430.1 - 0.039 13.8 0.0 0.039 13.8 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGD92430.1 - 0.04 13.8 10.9 1.7 8.6 1.7 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGD92430.1 - 0.066 13.0 7.3 0.8 9.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGD92430.1 - 0.08 12.5 5.5 0.35 10.5 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGD92430.1 - 4.7 7.9 25.2 0.31 11.5 0.5 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Fungal_trans PF04082.13 EGD92431.1 - 2.6e-09 36.3 0.0 4.6e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD92431.1 - 9.4e-08 31.8 11.1 1.7e-07 30.9 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Filo_VP35 PF02097.10 EGD92431.1 - 0.025 13.7 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 Methyltransf_23 PF13489.1 EGD92432.1 - 1e-15 57.8 0.1 1.3e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD92432.1 - 4.6e-12 46.2 0.0 1.1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD92432.1 - 2.6e-11 43.3 0.0 5e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD92432.1 - 1.8e-09 37.9 0.0 3.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD92432.1 - 1.4e-08 35.2 0.0 4.4e-08 33.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD92432.1 - 1e-06 29.0 0.0 1.6e-05 25.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EGD92432.1 - 4e-06 25.9 0.0 4.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 EGD92432.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF2380 PF09533.5 EGD92432.1 - 0.021 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Methyltransf_32 PF13679.1 EGD92432.1 - 0.025 14.2 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EGD92432.1 - 0.036 13.1 0.0 0.44 9.6 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_19 PF04672.7 EGD92432.1 - 0.055 12.7 0.0 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl methyltransferase Methyltransf_26 PF13659.1 EGD92432.1 - 0.078 13.0 0.0 1 9.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EGD92432.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB Fungal_trans PF04082.13 EGD92433.1 - 2e-10 39.9 0.0 3.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD92433.1 - 1.2e-07 31.4 6.9 1.2e-07 31.4 4.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.3 EGD92434.1 - 2e-35 121.6 3.2 4.2e-35 120.5 2.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF4164 PF13747.1 EGD92434.1 - 0.061 13.4 6.7 0.14 12.3 4.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) BMFP PF04380.8 EGD92434.1 - 0.092 12.8 3.4 0.23 11.6 2.4 1.7 1 0 0 1 1 1 0 Membrane fusogenic activity bZIP_1 PF00170.16 EGD92434.1 - 0.13 12.1 11.4 0.092 12.7 6.1 2.0 1 1 1 2 2 2 0 bZIP transcription factor Actin PF00022.14 EGD92435.1 - 1.4e-116 389.1 0.0 1.8e-116 388.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGD92435.1 - 0.056 12.0 0.0 0.35 9.4 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein EamA PF00892.15 EGD92436.1 - 5.7e-09 36.0 30.1 2.8e-05 24.1 1.6 2.7 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EGD92436.1 - 7.8e-06 26.0 18.2 0.00025 21.2 0.4 2.7 2 0 0 2 2 2 2 Multidrug resistance efflux transporter PgaD PF13994.1 EGD92436.1 - 0.0038 16.7 0.8 0.0038 16.7 0.6 3.2 3 2 2 5 5 5 1 PgaD-like protein TPT PF03151.11 EGD92436.1 - 0.16 11.5 24.7 0.016 14.8 6.9 2.8 3 1 0 3 3 3 0 Triose-phosphate Transporter family Aldo_ket_red PF00248.16 EGD92437.1 - 2.8e-54 183.8 0.0 3.2e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tubulin PF00091.20 EGD92438.1 - 2.1e-65 220.5 0.0 3.1e-65 219.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGD92438.1 - 1.9e-43 147.4 0.8 2.9e-43 146.9 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain HisG PF01634.13 EGD92438.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATP phosphoribosyltransferase Aa_trans PF01490.13 EGD92439.1 - 2.2e-39 135.0 39.0 2.7e-39 134.8 27.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 EGD92439.1 - 0.0028 17.2 3.4 0.0028 17.2 2.4 2.9 3 0 0 3 3 3 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Tetraspannin PF00335.15 EGD92439.1 - 0.11 11.7 0.2 0.11 11.7 0.1 4.7 4 1 1 5 5 5 0 Tetraspanin family Crystall PF00030.14 EGD92440.1 - 0.0038 17.0 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin DUF883 PF05957.8 EGD92441.1 - 0.014 15.8 0.1 0.015 15.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4449 PF14613.1 EGD92441.1 - 0.024 14.5 1.4 0.025 14.5 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) YtxH PF12732.2 EGD92441.1 - 0.068 13.5 2.7 0.078 13.3 1.9 1.2 1 0 0 1 1 1 0 YtxH-like protein WXG100 PF06013.7 EGD92441.1 - 0.074 13.0 1.2 0.088 12.8 0.8 1.1 1 0 0 1 1 1 0 Proteins of 100 residues with WXG CsbD PF05532.7 EGD92441.1 - 1.3 8.7 11.7 16 5.2 8.1 2.4 1 1 0 1 1 1 0 CsbD-like Robl_LC7 PF03259.12 EGD92442.1 - 2e-05 24.0 0.1 0.12 11.9 0.0 3.2 3 0 0 3 3 3 2 Roadblock/LC7 domain MRI PF15325.1 EGD92442.1 - 0.036 15.0 5.0 0.036 15.0 3.5 1.9 1 1 1 2 2 2 0 Modulator of retrovirus infection Ipi1_N PF12333.3 EGD92443.1 - 3.2e-27 94.4 2.6 3.7e-27 94.2 0.0 2.3 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation F-box PF00646.28 EGD92444.1 - 0.0011 18.5 0.1 0.0065 16.1 0.0 2.3 2 0 0 2 2 2 1 F-box domain TILa PF12714.2 EGD92444.1 - 0.053 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 TILa domain Pyrid_oxidase_2 PF13883.1 EGD92445.1 - 1.5e-36 125.7 0.0 2.5e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EGD92445.1 - 0.091 12.7 0.0 0.64 10.0 0.0 2.1 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF1771 PF08590.5 EGD92447.1 - 3.1e-23 81.5 7.8 3.3e-23 81.4 3.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EGD92447.1 - 7.7e-17 61.2 0.4 2.7e-16 59.4 0.3 2.0 1 0 0 1 1 1 1 Smr domain DUF605 PF04652.11 EGD92447.1 - 0.57 9.5 6.6 6.3 6.0 4.5 2.1 2 0 0 2 2 2 0 Vta1 like polyprenyl_synt PF00348.12 EGD92448.1 - 1.3e-62 211.0 0.0 2.1e-62 210.3 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase DUF4320 PF14208.1 EGD92448.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) SQS_PSY PF00494.14 EGD92450.1 - 5.3e-63 212.8 0.0 6.6e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RPE65 PF03055.10 EGD92451.1 - 2.7e-131 438.4 0.0 3.1e-131 438.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Amino_oxidase PF01593.19 EGD92452.1 - 2.5e-19 69.6 0.0 9.2e-19 67.8 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGD92452.1 - 1.9e-14 53.4 0.2 8.1e-14 51.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD92452.1 - 8.8e-12 44.5 0.0 1.9e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EGD92452.1 - 1.4e-07 30.3 0.2 0.0019 16.7 0.8 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EGD92452.1 - 2.3e-06 27.6 0.0 8.4e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD92452.1 - 8e-06 26.0 0.0 0.00043 20.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGD92452.1 - 9.7e-06 24.6 1.2 6.3e-05 21.9 1.5 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EGD92452.1 - 2.3e-05 23.6 1.6 0.00055 19.1 1.9 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGD92452.1 - 0.00026 20.1 0.8 0.00049 19.2 0.3 1.6 2 0 0 2 2 2 1 Thi4 family GDI PF00996.13 EGD92452.1 - 0.0025 16.1 0.1 0.031 12.6 0.0 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor NAD_binding_9 PF13454.1 EGD92452.1 - 0.0031 17.3 0.3 0.051 13.3 0.2 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EGD92452.1 - 0.0046 16.0 0.2 0.0085 15.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 EGD92452.1 - 0.027 14.7 0.0 0.063 13.5 0.0 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EGD92452.1 - 0.028 14.7 3.2 0.24 11.8 1.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGD92452.1 - 0.092 11.6 1.0 0.21 10.4 0.3 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.11 EGD92452.1 - 0.17 11.3 0.1 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 EGD92452.1 - 0.17 11.2 0.3 0.72 9.1 0.1 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain GIDA PF01134.17 EGD92452.1 - 0.18 10.5 2.5 0.37 9.6 0.8 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.13 EGD92452.1 - 0.2 11.6 0.2 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain TPR_12 PF13424.1 EGD92453.1 - 1.1e-07 31.6 3.1 0.014 15.3 0.0 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGD92453.1 - 8.9e-06 25.9 3.3 1.5 9.6 0.2 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGD92453.1 - 9.8e-05 22.1 1.4 0.16 11.9 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGD92453.1 - 0.0006 19.5 0.8 0.38 10.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGD92453.1 - 0.0075 15.8 0.0 2.7 7.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGD92453.1 - 0.029 14.1 0.0 3 7.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGD92453.1 - 1.1 9.6 5.7 8.9 6.7 0.1 3.9 3 2 1 4 4 4 0 Tetratricopeptide repeat BTB PF00651.26 EGD92454.1 - 1.2e-07 31.6 0.0 2.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.17 EGD92454.1 - 1.9e-07 31.1 0.0 3.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain I-set PF07679.11 EGD92454.1 - 0.048 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain SH3_5 PF08460.5 EGD92454.1 - 0.084 12.7 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain HLH PF00010.21 EGD92455.1 - 4.4e-12 45.5 1.0 8.7e-12 44.5 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2681 PF10883.3 EGD92455.1 - 0.75 10.0 6.8 4.2 7.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Filo_VP35 PF02097.10 EGD92455.1 - 3.1 6.9 8.6 3.4 6.7 1.1 2.4 1 1 0 2 2 2 0 Filoviridae VP35 Mnd1 PF03962.10 EGD92455.1 - 5 6.7 7.6 13 5.3 5.1 1.7 1 1 0 1 1 1 0 Mnd1 family HCV_NS5a_1a PF08300.8 EGD92457.1 - 0.052 13.4 0.7 0.11 12.4 0.5 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain CN_hydrolase PF00795.17 EGD92458.1 - 3e-12 46.2 0.0 2e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Clr5 PF14420.1 EGD92459.1 - 3.1e-14 52.5 0.1 6e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Clr5 domain SAC3_GANP PF03399.11 EGD92460.1 - 2.3e-54 184.0 2.3 3.5e-54 183.4 1.6 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGD92460.1 - 0.0022 17.7 0.4 0.0061 16.3 0.3 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 HC2 PF07382.6 EGD92460.1 - 0.34 10.7 20.8 0.68 9.7 14.4 1.4 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Zip PF02535.17 EGD92461.1 - 2e-46 158.4 5.3 2.5e-46 158.1 3.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter 7TM_transglut PF14402.1 EGD92461.1 - 0.0013 17.7 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 7 transmembrane helices usually fused to an inactive transglutaminase DUF3353 PF11833.3 EGD92461.1 - 0.17 11.3 3.7 10 5.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) DUF805 PF05656.9 EGD92461.1 - 2 8.2 6.8 1.2 8.9 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF2841 PF11001.3 EGD92462.1 - 7.6e-49 164.7 0.1 1.3e-48 163.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) CorA PF01544.13 EGD92462.1 - 0.23 10.4 0.2 0.34 9.8 0.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ABC_membrane PF00664.18 EGD92467.1 - 2.1e-82 276.6 31.1 9.2e-45 153.1 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD92467.1 - 6.2e-52 175.5 0.0 1.5e-30 106.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGD92467.1 - 3e-10 39.6 0.7 0.00015 21.1 0.0 4.0 2 2 2 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGD92467.1 - 1.5e-06 28.3 2.6 0.016 15.1 0.7 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGD92467.1 - 4.7e-06 25.8 0.7 0.0018 17.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGD92467.1 - 1.2e-05 25.2 0.1 0.22 11.5 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EGD92467.1 - 2.1e-05 24.0 0.2 0.19 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EGD92467.1 - 0.00077 19.9 0.6 1.1 9.7 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EGD92467.1 - 0.0014 18.0 0.3 1.1 8.8 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EGD92467.1 - 0.0015 18.4 0.8 0.13 12.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.1 EGD92467.1 - 0.0069 16.3 1.3 2.2 8.1 0.1 3.7 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 EGD92467.1 - 0.0082 15.9 2.5 1.2 8.8 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_23 PF13476.1 EGD92467.1 - 0.015 15.6 0.1 0.69 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGD92467.1 - 0.015 15.4 0.0 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 EGD92467.1 - 0.031 13.8 2.9 7.7 6.0 0.3 3.5 3 1 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGD92467.1 - 0.032 13.7 0.1 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EGD92467.1 - 0.032 14.3 1.8 4.2 7.5 0.0 3.2 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGD92467.1 - 0.063 12.3 0.1 6.8 5.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin GTP_EFTU PF00009.22 EGD92467.1 - 0.083 12.3 0.0 9.4 5.6 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EGD92467.1 - 0.19 11.1 4.2 12 5.2 0.1 3.2 2 1 0 3 3 3 0 AAA-like domain MobB PF03205.9 EGD92467.1 - 0.35 10.5 1.7 14 5.3 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EGD92467.1 - 0.86 9.2 4.8 4 7.0 0.0 3.3 3 0 0 3 3 3 0 NACHT domain Ank_5 PF13857.1 EGD92468.1 - 0.00014 22.0 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EGD92468.1 - 0.00034 20.2 0.0 0.00077 19.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 EGD92468.1 - 0.00051 20.0 0.0 0.0016 18.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EGD92468.1 - 0.0034 17.8 0.0 0.0074 16.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGD92468.1 - 0.0095 16.2 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-C2H2_2 PF12756.2 EGD92468.1 - 0.069 13.2 0.2 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.20 EGD92470.1 - 1.1e-58 198.3 0.1 2e-58 197.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92470.1 - 1.5e-26 93.0 0.0 5.6e-25 87.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.21 EGD92470.1 - 8.2e-11 41.8 0.0 2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EGD92470.1 - 0.001 18.1 0.0 0.0027 16.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGD92470.1 - 0.0014 18.4 0.0 0.0041 16.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Myb_DNA-bind_6 PF13921.1 EGD92471.1 - 8.5e-06 25.7 0.0 1.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD92471.1 - 0.0016 18.4 0.4 0.0043 17.0 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3431 PF11913.3 EGD92473.1 - 8.2e-60 202.0 0.0 3.1e-59 200.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) zf-C3HC4_2 PF13923.1 EGD92474.1 - 6.9e-08 32.3 11.4 1.2e-07 31.5 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EGD92474.1 - 9e-08 31.6 2.8 1.6e-07 30.7 2.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EGD92474.1 - 1.3e-07 31.1 6.6 2.2e-07 30.4 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD92474.1 - 8.1e-07 28.6 10.4 1.4e-06 27.9 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD92474.1 - 1.4e-05 24.6 11.8 2.5e-05 23.8 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD92474.1 - 1.5e-05 24.7 8.9 2.8e-05 23.8 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EGD92474.1 - 0.015 15.1 8.3 0.033 14.0 5.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Cript PF10235.4 EGD92474.1 - 0.019 15.3 2.6 0.019 15.3 1.8 2.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-RING_UBOX PF13445.1 EGD92474.1 - 0.074 12.7 7.3 0.17 11.6 5.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 EGD92474.1 - 0.22 11.0 3.8 0.37 10.3 2.6 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EGD92474.1 - 1.7 8.8 7.5 4.3 7.5 5.2 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger Mcp5_PH PF12814.2 EGD92475.1 - 1.9e-42 144.0 0.1 4.6e-42 142.8 0.1 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Methyltransf_23 PF13489.1 EGD92476.1 - 1.5e-11 44.2 0.0 1.8e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD92476.1 - 4.5e-06 27.0 0.0 7.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD92476.1 - 3.9e-05 24.0 0.0 6.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD92476.1 - 7.4e-05 22.3 0.0 9.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD92476.1 - 0.03 14.8 0.0 0.05 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2439 PF10382.4 EGD92477.1 - 2.8e-26 91.5 0.0 5.3e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) DUF4023 PF13215.1 EGD92477.1 - 0.044 13.5 0.6 0.12 12.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) SH3_9 PF14604.1 EGD92479.1 - 1.2e-13 50.3 0.1 2.5e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 EGD92479.1 - 8.5e-13 48.3 0.2 1.2e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EGD92479.1 - 1.1e-12 47.0 0.1 2.2e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGD92479.1 - 2.1e-10 39.9 0.1 4.6e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Colicin_C PF12106.3 EGD92479.1 - 0.095 12.3 1.0 0.28 10.7 0.7 1.8 1 0 0 1 1 1 0 Colicin C terminal ribonuclease domain TSC21 PF15217.1 EGD92480.1 - 0.043 13.4 0.1 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 TSC21 family RTC PF01137.16 EGD92482.1 - 1.2e-32 112.5 0.0 1.8e-17 62.9 0.1 3.9 2 2 1 3 3 3 3 RNA 3'-terminal phosphate cyclase DUF2786 PF10979.3 EGD92483.1 - 1.7e-13 50.0 1.2 1.7e-13 50.0 0.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) CMV_1a PF12467.3 EGD92483.1 - 0.52 10.6 11.1 0.18 12.1 1.3 3.2 3 1 1 4 4 4 0 Cucumber mosaic virus 1a protein family Cid2 PF09774.4 EGD92483.1 - 7.3 6.6 10.2 0.48 10.5 0.1 3.1 3 0 0 3 3 3 0 Caffeine-induced death protein 2 Exo_endo_phos PF03372.18 EGD92484.1 - 1e-16 61.6 1.1 1.3e-16 61.2 0.8 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF706 PF05153.10 EGD92485.1 - 2.4e-128 426.7 2.7 3e-128 426.4 1.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EGD92485.1 - 0.11 12.4 1.0 0.79 9.7 0.0 2.5 3 0 0 3 3 3 0 HD domain Cep57_CLD_2 PF14197.1 EGD92485.1 - 0.26 11.2 2.4 2.1 8.3 0.3 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 HNH_2 PF13391.1 EGD92487.1 - 2.2e-14 52.9 0.3 6.2e-14 51.5 0.1 1.9 2 0 0 2 2 2 1 HNH endonuclease Abhydrolase_1 PF00561.15 EGD92488.1 - 7.4e-43 146.7 0.1 5e-42 144.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGD92488.1 - 2e-12 47.4 1.0 1.4e-11 44.7 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD92488.1 - 0.0017 18.0 0.2 0.032 13.9 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EGD92488.1 - 0.055 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Gly_transf_sug PF04488.10 EGD92490.1 - 7.4e-17 61.6 0.1 1.8e-16 60.3 0.1 1.6 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EGD92490.1 - 0.006 15.7 0.1 0.019 14.1 0.0 1.8 2 0 0 2 2 2 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EGD92490.1 - 0.16 10.3 5.0 0.23 9.8 0.3 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain zf-C2H2_7 PF15269.1 EGD92490.1 - 0.19 11.6 0.4 0.57 10.0 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger MFS_1 PF07690.11 EGD92491.1 - 1.9e-34 118.9 29.3 3.1e-34 118.2 20.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4231 PF14015.1 EGD92491.1 - 0.74 9.8 4.1 0.44 10.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Methyltransf_8 PF05148.10 EGD92492.1 - 0.22 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase SSP160 PF06933.6 EGD92492.1 - 4.5 5.1 19.5 6.7 4.5 13.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tho2 PF11262.3 EGD92493.1 - 3.3e-93 312.0 0.0 4.7e-93 311.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EGD92493.1 - 1.6e-28 98.2 0.0 4e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit APH PF01636.18 EGD92494.1 - 5.5e-10 39.3 0.1 8e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD92494.1 - 0.00095 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EGD92494.1 - 0.15 11.2 0.1 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase GFA PF04828.9 EGD92495.1 - 6.4e-19 67.6 0.0 9.7e-19 67.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Vps5 PF09325.5 EGD92496.1 - 1.7e-13 50.4 3.0 3e-13 49.5 2.1 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EGD92496.1 - 1.8e-08 34.1 0.0 3.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 PX domain GTP_EFTU PF00009.22 EGD92497.1 - 5e-54 182.6 0.0 8.5e-54 181.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EGD92497.1 - 1.6e-24 85.4 0.0 4.2e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EGD92497.1 - 2.5e-17 62.5 0.1 1.3e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGD92497.1 - 4.3e-05 23.5 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EGD92497.1 - 0.0049 16.4 0.2 0.19 11.3 0.0 2.7 3 0 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EGD92497.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ArfGap PF01412.13 EGD92498.1 - 2.1e-32 111.3 0.0 3.4e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.17 EGD92499.1 - 2.5e-29 100.7 0.1 1.8e-14 53.1 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD92499.1 - 1.8e-22 79.1 0.0 9.3e-11 41.5 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD92499.1 - 4.3e-08 32.8 0.0 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 EGD92499.1 - 0.087 11.3 6.2 0.13 10.7 4.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MARVEL PF01284.18 EGD92501.1 - 1.7e-06 27.8 3.6 2.9e-06 27.1 2.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain Choline_transpo PF04515.7 EGD92501.1 - 0.0027 16.5 0.6 0.0067 15.2 0.4 1.6 1 1 0 1 1 1 1 Plasma-membrane choline transporter SecG PF03840.9 EGD92501.1 - 0.0074 16.0 0.9 1.3 8.8 0.0 2.8 3 0 0 3 3 3 2 Preprotein translocase SecG subunit DUF2456 PF10445.4 EGD92501.1 - 8.3 6.3 8.6 0.63 9.9 0.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2456) ATP-grasp_4 PF13535.1 EGD92502.1 - 1.5e-11 44.3 0.0 5.2e-11 42.6 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGD92502.1 - 1.4e-10 41.2 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGD92502.1 - 0.00099 17.9 0.0 0.13 10.9 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GFO_IDH_MocA_C PF02894.12 EGD92503.1 - 1.7e-13 50.3 0.0 2.5e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 EGD92503.1 - 0.0013 19.2 0.1 0.0027 18.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF951 PF06107.6 EGD92504.1 - 0.11 12.0 1.8 0.31 10.5 0.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) HPP PF04982.8 EGD92506.1 - 1.7e-37 127.8 7.3 1.7e-37 127.8 5.1 1.4 2 0 0 2 2 2 1 HPP family DUF599 PF04654.7 EGD92506.1 - 0.0079 15.3 2.5 1.2 8.1 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF599 DUF3377 PF11857.3 EGD92506.1 - 0.039 13.5 0.8 0.16 11.5 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Yip1 PF04893.12 EGD92506.1 - 0.051 13.0 11.1 1.4 8.3 0.4 2.6 1 1 2 3 3 3 0 Yip1 domain ABC_cobalt PF09819.4 EGD92506.1 - 0.68 9.8 5.9 0.091 12.7 0.9 1.8 2 0 0 2 2 2 0 ABC-type cobalt transport system, permease component MFS_1 PF07690.11 EGD92507.1 - 3.9e-37 127.7 53.5 3.9e-37 127.7 37.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD92507.1 - 6e-17 61.3 10.5 6e-17 61.3 7.3 3.5 2 1 2 5 5 5 1 Sugar (and other) transporter TRI12 PF06609.8 EGD92507.1 - 8.4e-15 53.9 15.2 1.4e-14 53.2 10.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4267 PF14087.1 EGD92508.1 - 1.6e-25 88.8 3.2 1.8e-25 88.7 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) p450 PF00067.17 EGD92510.1 - 7.3e-21 74.2 0.0 4.9e-19 68.1 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.22 EGD92511.1 - 3e-35 121.5 0.0 2.2e-23 83.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EGD92511.1 - 2.2e-20 72.2 3.1 2.2e-20 72.2 2.2 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EGD92511.1 - 3.6e-15 56.6 1.0 0.00048 20.1 0.0 3.3 3 0 0 3 3 3 3 AAA domain SMC_N PF02463.14 EGD92511.1 - 2.6e-08 33.3 0.1 0.001 18.3 0.1 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGD92511.1 - 0.00014 22.2 0.7 0.06 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGD92511.1 - 0.00017 21.0 0.0 0.00047 19.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGD92511.1 - 0.0006 19.0 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EGD92511.1 - 0.0017 18.2 0.6 0.39 10.6 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EGD92511.1 - 0.0072 16.6 0.1 0.026 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGD92511.1 - 0.018 15.0 0.0 0.065 13.1 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 EGD92511.1 - 0.035 13.7 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EGD92511.1 - 0.076 13.1 0.0 0.28 11.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGD92511.1 - 0.097 12.5 0.1 0.097 12.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EGD92511.1 - 0.12 12.2 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.18 EGD92511.1 - 0.15 11.8 1.7 0.54 10.0 0.0 2.4 2 1 0 2 2 2 0 Dynamin family Cyclin_N PF00134.18 EGD92512.1 - 0.0001 21.8 0.0 0.00028 20.4 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain UQ_con PF00179.21 EGD92513.1 - 1.4e-42 144.4 0.0 1.8e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EGD92513.1 - 3.3e-06 26.6 0.0 6.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EGD92513.1 - 5.7e-05 22.8 0.0 9.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGD92513.1 - 0.053 13.4 0.0 0.094 12.6 0.0 1.4 1 1 0 1 1 1 0 RWD domain APH PF01636.18 EGD92514.1 - 2.3e-14 53.7 0.1 3.5e-13 49.8 0.0 2.8 3 1 0 3 3 3 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGD92514.1 - 0.11 11.1 0.1 2.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) AAA PF00004.24 EGD92515.1 - 8.2e-41 139.3 0.0 1.5e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD92515.1 - 4.6e-07 30.0 0.3 0.00017 21.6 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGD92515.1 - 1.4e-05 25.1 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EGD92515.1 - 5.3e-05 22.9 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EGD92515.1 - 6.5e-05 21.9 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EGD92515.1 - 0.001 19.0 0.4 0.0033 17.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD92515.1 - 0.0012 18.8 0.1 0.011 15.7 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EGD92515.1 - 0.0014 17.7 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGD92515.1 - 0.0016 18.1 0.4 0.0036 17.0 0.3 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGD92515.1 - 0.005 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGD92515.1 - 0.0093 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EGD92515.1 - 0.015 14.9 0.5 0.8 9.3 0.1 2.9 2 1 0 3 3 3 0 NACHT domain AAA_14 PF13173.1 EGD92515.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGD92515.1 - 0.023 15.4 0.3 0.066 14.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 EGD92515.1 - 0.029 13.0 1.4 0.04 12.6 0.1 1.8 2 1 0 2 2 2 0 TIP49 C-terminus KaiC PF06745.8 EGD92515.1 - 0.031 13.4 0.4 0.34 10.0 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_3 PF07726.6 EGD92515.1 - 0.038 13.5 0.0 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGD92515.1 - 0.053 13.8 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGD92515.1 - 0.074 11.8 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 EGD92515.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGD92515.1 - 0.086 12.0 1.3 0.53 9.4 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 EGD92515.1 - 0.09 11.7 0.1 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EGD92515.1 - 0.1 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EGD92515.1 - 0.5 9.7 5.5 0.83 9.0 0.3 2.7 2 1 0 3 3 3 0 AAA domain WD40 PF00400.27 EGD92516.1 - 4.3e-19 67.6 11.4 2.4e-06 27.2 0.3 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGD92516.1 - 0.096 12.3 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Mg_trans_NIPA PF05653.9 EGD92517.1 - 2.6e-65 220.3 8.8 1.3e-62 211.4 4.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EGD92517.1 - 7.4e-06 26.1 0.7 7.4e-06 26.1 0.5 3.1 2 1 0 2 2 2 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EGD92517.1 - 0.00046 19.1 4.0 0.00075 18.4 2.4 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EGD92517.1 - 0.00057 19.9 1.3 0.00057 19.9 0.9 3.6 3 1 1 4 4 4 1 EamA-like transporter family TctB PF07331.6 EGD92517.1 - 0.00085 18.9 6.6 0.63 9.6 4.2 3.2 3 0 0 3 3 3 2 Tripartite tricarboxylate transporter TctB family DoxX_2 PF13564.1 EGD92517.1 - 0.083 12.8 6.7 3.4 7.7 0.4 2.5 2 0 0 2 2 2 0 DoxX-like family BAF1_ABF1 PF04684.8 EGD92518.1 - 0.1 11.4 11.4 0.26 10.1 7.9 1.7 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HALZ PF02183.13 EGD92518.1 - 0.19 11.4 6.1 4.8 6.9 0.4 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Med30 PF11315.3 EGD92518.1 - 0.27 11.3 8.7 0.37 10.9 0.1 2.7 3 0 0 3 3 3 0 Mediator complex subunit 30 bZIP_1 PF00170.16 EGD92518.1 - 2.5 8.1 11.1 4.6 7.2 4.1 2.6 2 0 0 2 2 2 0 bZIP transcription factor GRAM PF02893.15 EGD92519.1 - 4e-16 58.2 0.0 1e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 GRAM domain TPR_11 PF13414.1 EGD92520.1 - 1.9e-12 46.6 1.4 6.9e-08 32.0 1.3 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGD92520.1 - 6.6e-06 25.6 7.7 0.011 15.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGD92520.1 - 2.3e-05 23.7 3.2 0.41 10.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD92520.1 - 0.00018 21.3 4.7 0.017 15.0 0.4 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EGD92520.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGD92520.1 - 0.0012 18.5 0.3 0.0069 16.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGD92520.1 - 0.0047 16.6 1.8 0.5 10.2 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat RRM_5 PF13893.1 EGD92520.1 - 0.013 15.2 0.0 0.043 13.6 0.0 1.8 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_16 PF13432.1 EGD92520.1 - 0.016 15.9 3.7 6.2 7.6 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGD92520.1 - 0.046 13.5 3.4 11 6.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGD92520.1 - 0.094 13.4 5.8 8 7.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD92520.1 - 4.6 7.9 7.2 4.9 7.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Asp PF00026.18 EGD92521.1 - 9.5e-30 103.9 1.3 1.2e-29 103.5 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGD92521.1 - 0.062 13.2 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Cu_amine_oxid PF01179.15 EGD92522.1 - 1.7e-121 405.8 0.8 2.2e-121 405.4 0.5 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EGD92522.1 - 1.6e-17 63.4 0.1 3.3e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EGD92522.1 - 3.3e-16 59.1 0.0 6.1e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CAF1 PF04857.15 EGD92523.1 - 4.2e-65 219.6 0.0 8.5e-65 218.6 0.0 1.5 2 0 0 2 2 2 1 CAF1 family ribonuclease NDUF_B12 PF08122.7 EGD92524.1 - 1.1e-06 28.3 4.4 6e-06 25.9 0.2 2.3 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B12 subunit family WD40 PF00400.27 EGD92525.1 - 9.6e-33 110.8 4.4 2.5e-06 27.1 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGD92525.1 - 5.3e-05 22.6 0.0 0.83 9.2 0.0 3.4 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.1 EGD92525.1 - 0.043 12.8 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Glyoxal_oxid_N PF07250.6 EGD92525.1 - 0.15 11.0 0.0 0.33 9.9 0.0 1.5 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus AMP-binding PF00501.23 EGD92526.1 - 1.3e-79 267.5 0.0 1.6e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD92526.1 - 1.7e-13 51.3 0.2 6.3e-13 49.4 0.2 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy_2 PF13532.1 EGD92527.1 - 2.6e-26 92.6 0.0 5.5e-26 91.5 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_L40e PF01020.12 EGD92527.1 - 0.19 11.3 1.1 0.58 9.7 0.8 1.8 1 0 0 1 1 1 0 Ribosomal L40e family CNH PF00780.17 EGD92528.1 - 6e-69 232.5 0.0 9.2e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EGD92528.1 - 8.7e-32 110.4 1.5 1.9e-31 109.3 1.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DNA_primase_S PF01896.14 EGD92528.1 - 7.7e-22 77.6 0.0 1.8e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit PH_5 PF15405.1 EGD92528.1 - 5e-15 55.6 0.0 2.2e-14 53.5 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGD92528.1 - 0.017 15.3 0.0 0.053 13.7 0.0 1.9 1 1 0 1 1 1 0 PH domain Ribosomal_S17e PF00833.13 EGD92528.1 - 0.18 11.5 0.2 0.48 10.1 0.1 1.7 1 0 0 1 1 1 0 Ribosomal S17 RabGAP-TBC PF00566.13 EGD92529.1 - 1.3e-46 158.8 0.0 2.2e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EGD92529.1 - 2.9e-06 26.6 3.0 0.011 15.5 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EGD92529.1 - 1.6e-05 23.8 0.3 0.19 11.1 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGD92529.1 - 5.6e-05 23.1 0.5 0.00027 21.0 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EGD92529.1 - 0.052 12.9 1.5 3.5 7.1 0.3 2.9 2 0 0 2 2 2 0 EF hand GRAM PF02893.15 EGD92529.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.8 1 1 0 1 1 1 0 GRAM domain Sigma70_ner PF04546.8 EGD92529.1 - 2.8 7.4 13.9 6.9 6.2 3.6 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region TPR_MLP1_2 PF07926.7 EGD92532.1 - 0.00013 21.6 7.3 0.00013 21.6 5.0 3.0 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EGD92532.1 - 0.0027 16.7 8.8 0.0027 16.7 6.1 2.0 1 1 1 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 EGD92532.1 - 0.0084 15.6 1.4 0.0084 15.6 1.0 2.5 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Armet PF10208.4 EGD92532.1 - 0.1 12.2 0.2 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding HALZ PF02183.13 EGD92532.1 - 0.19 11.5 6.4 9.9 5.9 0.2 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4200 PF13863.1 EGD92532.1 - 0.2 11.5 15.7 1.1 9.2 2.7 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) GAS PF13851.1 EGD92532.1 - 0.25 10.5 9.2 0.23 10.6 4.5 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding XkdW PF09636.5 EGD92532.1 - 0.33 10.8 3.7 0.92 9.4 0.1 3.1 3 0 0 3 3 3 0 XkdW protein AAA_13 PF13166.1 EGD92532.1 - 0.58 8.5 11.1 2.5 6.4 7.8 1.8 1 1 0 1 1 1 0 AAA domain THOC7 PF05615.8 EGD92532.1 - 1.2 9.4 12.4 4.8 7.4 1.7 2.7 1 1 1 2 2 2 0 Tho complex subunit 7 Reo_sigmaC PF04582.7 EGD92532.1 - 2.3 7.3 13.3 0.026 13.7 2.7 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein XhlA PF10779.4 EGD92532.1 - 2.6 8.0 4.4 17 5.4 0.0 2.9 3 0 0 3 3 3 0 Haemolysin XhlA CENP-F_leu_zip PF10473.4 EGD92532.1 - 9.9 6.0 25.5 0.18 11.6 3.2 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 adh_short_C2 PF13561.1 EGD92533.1 - 3.1e-21 76.2 0.8 4.3e-21 75.7 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD92533.1 - 2e-17 63.5 2.3 3.7e-17 62.7 1.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD92533.1 - 2e-05 24.3 1.0 6.5e-05 22.6 0.7 1.8 1 1 0 1 1 1 1 KR domain DUF1772 PF08592.6 EGD92534.1 - 0.0058 16.3 0.4 0.2 11.3 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) DUF401 PF04165.7 EGD92534.1 - 0.064 12.2 0.7 0.08 11.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF401) DUF566 PF04484.7 EGD92534.1 - 0.22 11.0 2.1 0.3 10.5 1.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) SAP PF02037.22 EGD92535.1 - 5.7e-09 35.2 0.1 1.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain JAB PF01398.16 EGD92536.1 - 1.1e-10 41.1 0.9 1.7e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RNA_pol_3_Rpc31 PF11705.3 EGD92538.1 - 6.7e-47 160.3 12.8 9e-47 159.9 8.9 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 EGD92538.1 - 0.0086 16.0 4.5 0.009 15.9 3.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit APH PF01636.18 EGD92539.1 - 5.1e-07 29.6 0.0 1.3e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family HCBP_related PF06594.6 EGD92539.1 - 0.15 11.6 0.1 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain GLE1 PF07817.8 EGD92539.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 GLE1-like protein FAD_binding_1 PF00667.15 EGD92540.1 - 4.4e-32 111.2 0.0 6.9e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGD92540.1 - 4.4e-31 107.8 0.0 2.4e-30 105.4 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EGD92540.1 - 3e-08 34.1 0.2 3.4e-06 27.5 0.1 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EGD92540.1 - 0.094 12.7 0.0 1.8 8.5 0.0 2.3 1 1 1 2 2 2 0 Flavodoxin domain FAD_binding_6 PF00970.19 EGD92540.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Flavodoxin_3 PF12641.2 EGD92540.1 - 0.11 11.8 0.0 0.68 9.3 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain ETF PF01012.16 EGD92541.1 - 3.2e-33 114.7 0.2 4.3e-33 114.3 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF500 PF04366.7 EGD92542.1 - 3.3e-43 146.1 0.0 5.8e-43 145.3 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) TFIIA PF03153.8 EGD92542.1 - 0.00087 19.2 3.5 0.00087 19.2 2.4 2.7 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PARP PF00644.15 EGD92543.1 - 8.6e-64 214.7 0.0 8.6e-64 214.7 0.0 3.3 3 1 1 4 4 4 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EGD92543.1 - 5e-41 139.4 0.2 8.4e-41 138.7 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EGD92543.1 - 1.9e-21 75.8 0.2 1.9e-21 75.8 0.2 2.6 3 0 0 3 3 3 1 WGR domain BRCT PF00533.21 EGD92543.1 - 7.1e-12 45.3 0.0 3.6e-11 43.0 0.0 2.2 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGD92543.1 - 2.2e-08 33.8 0.1 8.2e-08 31.9 0.1 2.0 2 0 0 2 2 2 1 twin BRCT domain GAGA_bind PF06217.7 EGD92543.1 - 1.3 8.9 23.9 1.2 8.9 1.4 2.3 1 1 1 2 2 2 0 GAGA binding protein-like family HpaP PF09483.5 EGD92543.1 - 2.1 8.2 15.4 4.8 7.0 10.7 1.5 1 0 0 1 1 1 0 Type III secretion protein (HpaP) DUF4407 PF14362.1 EGD92543.1 - 9.5 5.0 8.9 24 3.7 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Acetyltransf_3 PF13302.1 EGD92544.1 - 7.3e-09 35.9 0.0 1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD92544.1 - 0.00014 21.8 0.0 0.00046 20.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EGD92544.1 - 0.061 13.2 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_S10 PF00450.17 EGD92545.1 - 1.4e-83 281.3 6.9 7.7e-83 278.9 4.8 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase TcdA_TcdB PF12919.2 EGD92546.1 - 0.09 11.2 0.1 0.11 10.9 0.1 1.0 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Gyro_capsid PF04162.7 EGD92546.1 - 1.3 7.1 8.4 1.5 6.9 5.8 1.1 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) GATase PF00117.23 EGD92547.1 - 8.7e-47 159.0 0.0 2.1e-46 157.8 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EGD92547.1 - 2.1e-44 150.2 0.0 7.1e-44 148.4 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Leader_CPA1 PF08252.6 EGD92547.1 - 4.5e-11 41.7 0.1 9.7e-11 40.6 0.0 1.6 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide Peptidase_C26 PF07722.8 EGD92547.1 - 6e-06 25.8 0.3 0.00032 20.1 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 RNA_pol_I_A49 PF06870.7 EGD92548.1 - 5.4e-53 179.9 0.0 8.4e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor HOASN PF14515.1 EGD92548.1 - 0.88 9.9 4.7 0.49 10.8 1.4 1.9 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices Aminotran_1_2 PF00155.16 EGD92549.1 - 6.3e-86 288.5 0.0 1.1e-85 287.7 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGD92549.1 - 1.4e-06 26.8 0.0 2.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGD92549.1 - 5e-05 22.5 0.2 9.5e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGD92549.1 - 6.8e-05 21.7 0.0 0.00013 20.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGD92549.1 - 0.0071 15.5 0.4 0.023 13.8 0.2 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase p450 PF00067.17 EGD92550.1 - 5.8e-20 71.2 0.0 7.7e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDI PF02234.14 EGD92550.1 - 0.054 13.2 0.3 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor p450 PF00067.17 EGD92551.1 - 6.7e-66 222.6 0.0 9e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.1 EGD92551.1 - 0.062 13.2 0.5 21 5.1 0.1 3.2 3 0 0 3 3 3 0 Stirrup Vps54 PF07928.7 EGD92552.1 - 2.6e-22 79.4 0.0 7.4e-22 77.9 0.0 1.8 1 0 0 1 1 1 1 Vps54-like protein SNF2_N PF00176.18 EGD92553.1 - 3.5e-81 272.2 0.7 3.5e-81 272.2 0.5 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EGD92553.1 - 1.7e-24 85.5 0.2 1.4e-23 82.5 0.3 2.3 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 EGD92553.1 - 1.4e-17 63.3 0.0 1.2e-16 60.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 EGD92553.1 - 1.4e-17 63.6 0.4 1.4e-17 63.6 0.3 3.6 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EGD92553.1 - 4.7e-16 58.3 9.6 4.7e-16 58.3 6.6 2.6 2 0 0 2 2 2 1 HSA QLQ PF08880.6 EGD92553.1 - 6e-13 47.9 5.2 3.6e-12 45.4 3.6 2.4 1 0 0 1 1 1 1 QLQ BAR PF03114.13 EGD92554.1 - 1.1e-44 152.7 7.8 1.3e-44 152.4 5.4 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EGD92554.1 - 2.2e-08 33.3 3.9 2.9e-08 32.9 2.7 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking MscS_TM PF12794.2 EGD92554.1 - 5 5.6 4.2 7.6 5.0 2.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Ada_Zn_binding PF02805.11 EGD92556.1 - 6.8e-29 99.2 4.3 1.2e-28 98.4 3.0 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EGD92556.1 - 2.7e-07 30.1 0.0 5.8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EGD92556.1 - 0.0016 18.5 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Ribosomal_L2_C PF03947.13 EGD92557.1 - 3.4e-37 127.1 4.5 5.7e-37 126.4 3.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGD92557.1 - 1.3e-12 47.5 0.1 2.7e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.1 EGD92558.1 - 0.00055 19.7 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 EGD92558.1 - 0.026 14.4 0.3 0.11 12.5 0.2 2.0 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Nop14 PF04147.7 EGD92558.1 - 0.56 8.0 4.3 0.8 7.5 3.0 1.3 1 0 0 1 1 1 0 Nop14-like family DUF1770 PF08589.5 EGD92559.1 - 2.8e-16 59.9 0.0 3.8e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PfkB PF00294.19 EGD92560.1 - 1.5e-64 218.0 0.1 1.7e-64 217.8 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EGD92560.1 - 1.4e-05 24.4 0.0 2.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PS_pyruv_trans PF04230.8 EGD92560.1 - 0.0045 16.7 0.0 0.0061 16.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase CbiK PF06180.6 EGD92560.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) EST1_DNA_bind PF10373.4 EGD92561.1 - 4.7e-56 190.0 3.9 8e-56 189.2 2.7 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EGD92561.1 - 2.3e-17 63.2 0.4 7.5e-17 61.5 0.1 2.0 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EGD92561.1 - 0.022 14.4 0.4 0.06 12.9 0.3 1.8 1 0 0 1 1 1 0 TPR repeat Acyl-CoA_dh_1 PF00441.19 EGD92562.1 - 3.5e-31 108.3 2.3 5.8e-31 107.6 1.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGD92562.1 - 4.5e-16 58.0 0.0 1e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGD92562.1 - 1.2e-15 57.9 4.9 2.1e-15 57.1 3.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGD92562.1 - 3.7e-13 50.0 0.6 1e-12 48.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain IGPD PF00475.13 EGD92563.1 - 2.8e-59 199.1 1.2 4.3e-59 198.5 0.8 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Spo12 PF05032.7 EGD92564.1 - 1.6e-14 53.1 0.6 3.4e-14 52.1 0.4 1.6 1 0 0 1 1 1 1 Spo12 family Sad1_UNC PF07738.8 EGD92565.1 - 3.9e-34 117.3 0.0 6.9e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Pkinase PF00069.20 EGD92566.1 - 1.4e-55 188.2 0.0 2.1e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92566.1 - 4.7e-33 114.3 0.0 7e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD92566.1 - 2.1e-10 40.0 0.0 5.5e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pep3_Vps18 PF05131.9 EGD92567.1 - 1e-46 158.0 0.0 2.6e-46 156.7 0.0 1.7 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EGD92567.1 - 3.4e-12 46.1 2.1 5e-06 26.1 0.0 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EGD92567.1 - 0.00049 19.8 0.7 0.0011 18.7 0.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGD92567.1 - 0.0018 17.9 0.8 0.0041 16.8 0.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF2175 PF09943.4 EGD92567.1 - 0.036 14.1 1.3 0.098 12.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Vps39_2 PF10367.4 EGD92567.1 - 0.068 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.20 EGD92567.1 - 0.18 11.4 2.5 0.12 12.0 0.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD92567.1 - 0.29 11.1 1.1 0.67 10.0 0.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SNF2_N PF00176.18 EGD92568.1 - 1.2e-70 237.6 3.9 1.2e-70 237.6 2.7 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 EGD92568.1 - 4e-52 175.9 22.5 4e-52 175.9 15.6 5.1 5 1 1 6 6 6 1 DNA-binding domain Helicase_C PF00271.26 EGD92568.1 - 7.3e-16 57.8 0.0 2.5e-15 56.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Na_H_Exchanger PF00999.16 EGD92569.1 - 8.5e-68 228.6 36.2 1.1e-67 228.2 25.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3522 PF12036.3 EGD92569.1 - 0.27 11.0 10.0 1.5 8.6 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3522) PepSY_TM_2 PF13703.1 EGD92569.1 - 1.3 9.2 8.6 0.38 10.9 0.2 3.7 3 1 0 3 3 3 0 PepSY-associated TM helix MFS_2 PF13347.1 EGD92572.1 - 2.7e-06 26.0 11.8 5.7e-06 24.9 3.7 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.10 EGD92572.1 - 0.00047 18.9 1.1 0.00087 18.1 0.8 1.4 1 0 0 1 1 1 1 PUCC protein STE PF02200.11 EGD92573.1 - 4e-62 207.2 0.3 7.5e-62 206.3 0.1 1.6 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 EGD92573.1 - 5.3e-12 45.3 10.5 8e-07 29.0 0.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD92573.1 - 7.6e-10 38.4 10.2 6.2e-05 23.0 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGD92573.1 - 1.1e-09 38.1 4.5 1.1e-09 38.1 3.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGD92573.1 - 0.00018 21.2 0.5 0.00044 20.0 0.0 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD92573.1 - 0.0083 16.2 0.7 0.19 11.9 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.5 EGD92573.1 - 0.012 16.1 1.7 0.032 14.8 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING_3 PF14369.1 EGD92573.1 - 0.036 14.0 0.1 0.099 12.6 0.1 1.8 1 0 0 1 1 1 0 zinc-finger zf-TRAF PF02176.13 EGD92573.1 - 0.058 13.7 2.6 0.1 12.9 1.8 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-Di19 PF05605.7 EGD92573.1 - 0.089 12.9 0.4 0.089 12.9 0.3 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding His_biosynth PF00977.16 EGD92575.1 - 1.9e-32 112.4 0.0 2.2e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EGD92575.1 - 0.1 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF2463 PF09591.5 EGD92576.1 - 0.009 15.6 0.4 0.0096 15.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) Radical_SAM PF04055.16 EGD92577.1 - 6.4e-18 65.4 0.1 1.8e-17 64.0 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EGD92577.1 - 3.4e-12 46.2 0.0 8.2e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CoA_binding PF02629.14 EGD92578.1 - 3e-26 91.7 5.3 7.6e-26 90.4 1.2 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EGD92578.1 - 1.7e-22 79.6 0.2 3e-22 78.8 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EGD92578.1 - 1.5e-07 31.1 0.1 3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EGD92578.1 - 7.7e-05 22.8 0.1 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Ribosomal_L5_C PF00673.16 EGD92579.1 - 2.8e-23 81.4 0.0 5.8e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Pkinase PF00069.20 EGD92580.1 - 2.8e-66 223.3 0.0 5.1e-66 222.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92580.1 - 4.3e-48 163.6 0.0 9.3e-48 162.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EGD92580.1 - 1.8e-31 108.1 0.0 6.4e-31 106.3 0.0 2.0 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EGD92580.1 - 6.4e-16 58.2 0.1 1.4e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGD92580.1 - 4.7e-14 51.9 0.0 1.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EGD92580.1 - 9.7e-08 31.3 0.0 0.00026 20.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 EGD92580.1 - 0.00031 21.1 0.0 0.00065 20.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 EGD92580.1 - 0.031 13.3 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EGD92580.1 - 0.15 10.8 0.1 0.75 8.5 0.0 2.1 3 0 0 3 3 3 0 Seadornavirus VP7 Fungal_trans PF04082.13 EGD92581.1 - 1.8e-11 43.3 1.5 4.1e-11 42.2 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EGD92582.1 - 0.00031 20.8 11.9 0.27 11.6 0.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD92582.1 - 0.065 13.3 0.7 0.44 10.7 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Radial_spoke PF04712.7 EGD92582.1 - 0.13 11.0 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein zf-C2H2 PF00096.21 EGD92582.1 - 0.16 12.3 8.0 1.4 9.4 0.1 3.6 2 1 1 3 3 3 0 Zinc finger, C2H2 type MMR_HSR1 PF01926.18 EGD92583.1 - 4.4e-17 62.0 0.4 8.9e-15 54.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGD92583.1 - 5.8e-06 25.6 0.6 9.5e-05 21.7 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EGD92583.1 - 0.00075 18.7 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EGD92583.1 - 0.0021 17.2 0.1 0.0043 16.1 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EGD92583.1 - 0.074 13.5 0.3 0.26 11.8 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EGD92583.1 - 0.22 11.3 7.8 0.26 11.0 0.4 3.5 3 1 1 4 4 4 0 Dynamin family DNA_pol_phi PF04931.8 EGD92583.1 - 1.9 6.1 18.7 2.8 5.5 13.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi LTV PF04180.9 EGD92584.1 - 1.3e-69 235.7 15.4 1.8e-69 235.3 10.7 1.1 1 0 0 1 1 1 1 Low temperature viability protein PLDc_2 PF13091.1 EGD92585.1 - 3.3e-14 52.7 0.0 1.1e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EGD92585.1 - 1.1e-08 34.5 2.4 0.0091 15.7 0.3 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif E2F_TDP PF02319.15 EGD92585.1 - 0.12 11.9 0.1 22 4.6 0.0 2.7 2 1 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain NDUFA12 PF05071.11 EGD92586.1 - 4.8e-28 97.6 2.1 6.5e-28 97.2 1.4 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TPR_2 PF07719.12 EGD92587.1 - 6.9e-09 34.9 1.2 0.069 13.0 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGD92587.1 - 8.2e-09 34.6 5.0 3.7e-05 23.1 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGD92587.1 - 6e-07 29.5 9.5 0.36 11.5 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGD92587.1 - 2.3e-06 27.8 4.9 0.28 11.5 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD92587.1 - 7.1e-06 25.5 8.9 0.0011 18.5 0.0 5.0 5 1 1 6 6 6 1 TPR repeat TPR_17 PF13431.1 EGD92587.1 - 9.5e-06 25.4 0.0 0.79 10.0 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGD92587.1 - 0.00055 19.4 2.4 0.069 12.7 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD92587.1 - 0.0019 18.8 17.4 3.5 8.4 0.0 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGD92587.1 - 0.44 11.1 2.7 7.8 7.2 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SNF2_N PF00176.18 EGD92588.1 - 6.6e-73 245.1 0.0 1e-72 244.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EGD92588.1 - 2.5e-13 49.8 0.0 5e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EGD92588.1 - 2.3e-10 40.1 0.0 6.8e-10 38.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EGD92588.1 - 3.3e-10 39.6 6.6 3.3e-10 39.6 4.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGD92588.1 - 2.2e-08 33.9 7.2 2.2e-08 33.9 5.0 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD92588.1 - 1.7e-07 30.7 7.4 1.7e-07 30.7 5.1 2.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD92588.1 - 8.3e-07 28.5 8.1 2.5e-06 27.0 5.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD92588.1 - 1.2e-06 28.4 1.5 4.7e-06 26.6 1.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGD92588.1 - 1.8e-05 24.3 5.1 1.8e-05 24.3 3.5 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGD92588.1 - 0.00032 20.5 8.5 0.00073 19.3 5.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EGD92588.1 - 0.002 17.6 3.9 0.021 14.3 3.1 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit HDA2-3 PF11496.3 EGD92588.1 - 0.011 14.6 0.0 0.72 8.6 0.0 2.6 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 U-box PF04564.10 EGD92588.1 - 0.014 15.3 0.1 0.074 13.0 0.0 2.2 2 0 0 2 2 2 0 U-box domain zf-RING_UBOX PF13445.1 EGD92588.1 - 0.029 14.0 5.4 0.1 12.3 3.8 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGD92588.1 - 0.13 12.0 1.8 0.49 10.2 1.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MBOAT_2 PF13813.1 EGD92589.1 - 4.1e-19 68.4 2.1 9e-19 67.3 1.5 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Big_4 PF07532.6 EGD92589.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) RIX1 PF08167.7 EGD92590.1 - 2.8e-54 183.2 0.3 7.5e-54 181.8 0.2 1.8 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis SNF2_N PF00176.18 EGD92591.1 - 2.1e-50 171.2 0.2 4.2e-50 170.2 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD92591.1 - 8.2e-14 51.2 0.0 2e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD92591.1 - 0.00016 21.5 0.0 0.0007 19.4 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SAM_1 PF00536.25 EGD92591.1 - 0.024 14.7 0.0 0.079 13.1 0.0 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGD92591.1 - 0.036 13.9 0.0 0.099 12.5 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) GSH_synth_ATP PF03917.12 EGD92592.1 - 9.6e-100 333.7 0.0 1.2e-99 333.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EGD92592.1 - 1.7e-27 95.5 0.0 3.2e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Bestrophin PF01062.16 EGD92596.1 - 1e-45 155.9 0.0 9.4e-45 152.7 0.0 1.9 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Aminotran_3 PF00202.16 EGD92597.1 - 1.5e-101 339.6 0.0 1.8e-101 339.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGD92597.1 - 0.0074 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Spt4 PF06093.8 EGD92598.1 - 8.8e-33 112.0 0.2 1.1e-32 111.7 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.6 EGD92598.1 - 0.059 13.1 0.7 0.15 11.8 0.2 1.7 1 1 1 2 2 2 0 Coronavirus gene 5 protein Metallophos PF00149.23 EGD92599.1 - 2.3e-36 125.0 0.0 3.2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EGD92599.1 - 2.3e-30 104.4 0.8 5e-30 103.3 0.6 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EGD92599.1 - 9.7e-22 76.4 3.9 2.6e-17 62.2 1.0 2.7 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 EGD92599.1 - 1.3e-12 46.7 4.7 9.7e-05 21.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGD92599.1 - 1.6e-10 40.0 4.4 0.00087 19.0 0.6 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD92599.1 - 1e-07 32.3 1.6 0.0043 17.6 0.1 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGD92599.1 - 2.2e-06 27.4 0.2 0.0013 18.5 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGD92599.1 - 0.00072 19.8 0.8 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD92599.1 - 0.001 18.9 0.7 0.0028 17.5 0.3 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGD92599.1 - 0.0013 19.0 1.1 2.7 8.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGD92599.1 - 0.0033 17.5 0.4 9.6 6.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD92599.1 - 0.0039 17.6 2.2 3.3 8.6 0.1 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD92599.1 - 0.018 14.8 0.5 0.28 11.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EGD92599.1 - 0.091 12.6 3.1 2.5 8.0 0.2 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF89 PF01937.14 EGD92600.1 - 1.2e-133 445.3 0.2 1.4e-133 445.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Cut12 PF11500.3 EGD92601.1 - 1.2e-45 154.9 12.6 1.2e-45 154.9 8.7 4.4 3 1 0 4 4 4 1 Spindle pole body formation-associated protein HGTP_anticodon2 PF12745.2 EGD92602.1 - 1.3e-83 280.3 0.1 1.3e-83 280.3 0.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EGD92602.1 - 1.2e-64 218.0 0.0 3.1e-36 124.8 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92602.1 - 1.4e-36 125.9 0.0 6.8e-19 67.9 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EGD92602.1 - 6.2e-17 61.5 0.7 2e-16 59.8 0.5 2.0 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 EGD92602.1 - 1.4e-12 47.3 0.4 7.6e-12 44.9 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.18 EGD92602.1 - 0.0089 15.7 0.1 0.0089 15.7 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family RRM_1 PF00076.17 EGD92603.1 - 0.00031 20.2 0.0 0.00068 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD92603.1 - 0.0042 16.9 0.0 0.0094 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ifi-6-16 PF06140.8 EGD92603.1 - 0.042 13.6 0.6 0.077 12.7 0.4 1.4 1 0 0 1 1 1 0 Interferon-induced 6-16 family zf-CCCH PF00642.19 EGD92603.1 - 0.042 13.5 1.7 0.075 12.7 1.1 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.18 EGD92604.1 - 1.9e-19 69.7 0.2 4.8e-19 68.4 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EGD92604.1 - 9.5e-18 63.7 0.4 2e-17 62.7 0.1 1.7 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.13 EGD92604.1 - 8.9e-13 47.8 0.0 1.3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGD92604.1 - 1.7e-05 24.6 0.4 0.021 14.6 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EGD92604.1 - 0.0011 19.4 0.0 0.0025 18.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EGD92604.1 - 0.038 13.0 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ArgK PF03308.11 EGD92604.1 - 0.048 12.4 0.1 0.12 11.1 0.1 1.6 1 0 0 1 1 1 0 ArgK protein DnaJ PF00226.26 EGD92605.1 - 7.9e-28 95.9 2.0 1.2e-27 95.3 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGD92605.1 - 7.5e-23 80.2 0.6 2e-20 72.4 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain PIG-X PF08320.7 EGD92606.1 - 7e-68 227.9 0.1 9.6e-68 227.5 0.1 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 RFX_DNA_binding PF02257.10 EGD92607.1 - 5.4e-29 100.1 0.1 1.3e-28 98.8 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.14 EGD92608.1 - 6.2e-30 102.8 8.2 8.5e-30 102.3 5.7 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF1649 PF07855.7 EGD92609.1 - 2e-61 206.4 0.0 2.3e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) DUF2922 PF11148.3 EGD92609.1 - 0.0066 16.0 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2922) Peroxin-3 PF04882.7 EGD92610.1 - 5.3e-144 480.1 0.0 6.2e-144 479.9 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Na_H_Exchanger PF00999.16 EGD92611.1 - 7.5e-69 232.0 45.4 1.1e-68 231.5 31.4 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MFS_1 PF07690.11 EGD92612.1 - 4.2e-38 130.9 28.9 4.2e-38 130.9 20.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3147 PF11345.3 EGD92612.1 - 0.29 11.1 5.4 1.2 9.2 0.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3147) Acyl_transf_3 PF01757.17 EGD92612.1 - 0.41 9.4 36.1 0.56 8.9 11.5 3.1 2 1 0 2 2 2 0 Acyltransferase family ThiF PF00899.16 EGD92614.1 - 8.7e-18 64.4 0.0 1.4e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family DUF2267 PF10025.4 EGD92614.1 - 0.09 12.8 0.3 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Ytp1 PF10355.4 EGD92615.1 - 1e-84 283.9 13.6 1e-84 283.9 9.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EGD92615.1 - 7.7e-32 108.9 3.3 7.7e-32 108.9 2.3 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Swi5 PF07061.6 EGD92616.1 - 1.7e-24 85.4 0.1 2.5e-24 84.8 0.1 1.4 1 1 0 1 1 1 1 Swi5 PEP-utilisers_N PF05524.8 EGD92616.1 - 0.034 13.9 0.1 0.064 13.0 0.0 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF641 PF04859.7 EGD92616.1 - 0.064 13.0 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Jnk-SapK_ap_N PF09744.4 EGD92616.1 - 0.077 12.9 0.5 0.11 12.4 0.3 1.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1366 PF07104.6 EGD92616.1 - 0.11 12.1 0.1 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) ARL6IP6 PF15062.1 EGD92616.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix ApoC-I PF04691.7 EGD92616.1 - 0.27 10.9 1.3 0.39 10.4 0.2 1.7 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Herpes_UL25 PF01499.11 EGD92617.1 - 0.1 10.8 5.3 0.2 9.9 3.7 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family CALCOCO1 PF07888.6 EGD92617.1 - 0.13 10.5 9.9 0.12 10.6 5.9 1.6 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF342 PF03961.8 EGD92617.1 - 0.21 9.9 4.1 0.41 9.0 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cauli_AT PF03233.8 EGD92617.1 - 0.33 10.6 5.8 0.33 10.6 1.6 2.2 2 0 0 2 2 2 0 Aphid transmission protein Filament PF00038.16 EGD92617.1 - 0.34 10.3 13.2 0.036 13.5 5.8 1.7 2 0 0 2 2 2 0 Intermediate filament protein IncA PF04156.9 EGD92617.1 - 0.37 10.3 10.9 0.1 12.1 4.5 2.3 3 0 0 3 3 3 0 IncA protein Rota_NSP4 PF01452.11 EGD92617.1 - 0.65 9.3 2.8 1.1 8.5 1.9 1.3 1 0 0 1 1 1 0 Rotavirus non structural protein DUF4407 PF14362.1 EGD92617.1 - 6.5 5.6 8.7 14 4.4 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2570 PF10828.3 EGD92617.1 - 9.6 5.8 10.1 30 4.2 7.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Glycos_transf_2 PF00535.21 EGD92618.1 - 3.4e-21 75.6 0.0 8.1e-11 41.8 0.0 3.0 1 1 1 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGD92618.1 - 5.6e-05 23.0 0.2 1.3 8.8 0.0 3.4 2 2 1 4 4 4 2 Glycosyltransferase like family 2 Dicty_CAR PF05462.6 EGD92619.1 - 3.9e-11 42.4 7.7 3.9e-11 42.4 5.3 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 EGD92619.1 - 3.4e-06 26.3 0.0 5.7e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.19 EGD92619.1 - 1.2e-05 24.4 11.1 2.7e-05 23.4 6.9 2.0 2 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) Git3 PF11710.3 EGD92619.1 - 0.00018 21.1 6.1 0.00018 21.1 4.2 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 EGD92619.1 - 0.0026 16.9 2.1 0.0043 16.2 1.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3_C PF11970.3 EGD92619.1 - 0.067 12.9 0.3 0.067 12.9 0.2 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Frizzled PF01534.12 EGD92619.1 - 1.1 7.9 12.2 66 2.1 8.5 2.4 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region Striatin PF08232.7 EGD92620.1 - 0.2 11.9 0.6 0.46 10.7 0.0 1.8 2 0 0 2 2 2 0 Striatin family Kdo PF06293.9 EGD92621.1 - 0.00017 20.7 0.0 0.00038 19.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD92621.1 - 0.0031 17.3 0.1 0.0031 17.3 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family CDC45 PF02724.9 EGD92621.1 - 0.07 11.1 0.1 0.12 10.4 0.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Autophagy_N PF03986.8 EGD92622.1 - 4.6e-47 159.4 0.1 4.6e-47 159.4 0.0 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EGD92622.1 - 4.2e-22 78.0 0.2 7.8e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EGD92622.1 - 2.1e-14 52.2 0.5 3.5e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal CENP-B_dimeris PF09026.5 EGD92622.1 - 0.36 11.1 9.6 0.57 10.4 3.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TFIIB PF00382.14 EGD92623.1 - 0.00036 20.2 0.0 0.03 14.1 0.0 2.6 2 1 0 2 2 2 2 Transcription factor TFIIB repeat FtsQ PF03799.10 EGD92623.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Cell division protein FtsQ EST1_DNA_bind PF10373.4 EGD92624.1 - 3.4e-13 49.4 0.5 3.4e-13 49.4 0.4 2.0 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain Sel1 PF08238.7 EGD92624.1 - 0.089 13.4 0.4 0.25 12.0 0.3 1.8 1 0 0 1 1 1 0 Sel1 repeat CDK5_activator PF03261.10 EGD92625.1 - 0.28 10.4 10.5 0.26 10.5 6.1 1.7 1 1 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Hid1 PF12722.2 EGD92625.1 - 2 5.9 10.5 2.5 5.6 7.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NUDIX PF00293.23 EGD92627.1 - 1.7e-08 34.1 0.0 2.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EGD92628.1 - 4.8e-18 65.0 0.0 7.8e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HAD_2 PF13419.1 EGD92629.1 - 1.4e-15 57.9 0.0 1.8e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD92629.1 - 2.9e-07 30.1 0.0 5.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 EGD92629.1 - 8.1e-07 28.8 0.0 8.3e-05 22.3 0.0 2.1 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase Hydrolase PF00702.21 EGD92629.1 - 0.0026 18.2 0.0 0.073 13.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase BRCT PF00533.21 EGD92629.1 - 0.078 13.1 0.0 2.1 8.5 0.0 3.0 3 1 1 4 4 4 0 BRCA1 C Terminus (BRCT) domain HipA_N PF07805.7 EGD92629.1 - 0.12 12.5 0.1 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 HipA-like N-terminal domain Init_tRNA_PT PF04179.7 EGD92630.1 - 1e-140 469.5 0.0 1.2e-140 469.3 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Aldo_ket_red PF00248.16 EGD92631.1 - 4.7e-12 45.3 0.0 6.2e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Tannase PF07519.6 EGD92633.1 - 2e-94 316.9 0.1 1.2e-93 314.4 0.1 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EGD92633.1 - 0.00012 21.3 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGD92633.1 - 0.0029 17.5 0.0 0.0064 16.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 EGD92634.1 - 6.1e-08 32.4 13.4 1.1e-07 31.6 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGD92634.1 - 9.5e-05 21.1 2.5 0.00022 19.9 1.8 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sec8_exocyst PF04048.9 EGD92635.1 - 4.2e-42 143.1 1.9 5.7e-42 142.7 0.5 1.9 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EGD92635.1 - 5.7e-08 32.0 0.4 1.1e-07 31.0 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) RNA_pol_Rpc82 PF05645.8 EGD92636.1 - 2.8e-25 89.3 0.1 6.1e-15 55.4 0.0 3.6 2 1 2 4 4 4 3 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EGD92636.1 - 2.3e-22 78.6 3.6 3.1e-15 55.8 0.1 4.2 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EGD92636.1 - 8.6e-09 34.8 0.0 8e-07 28.5 0.1 2.8 2 1 0 2 2 2 1 TFIIE alpha subunit TrmB PF01978.14 EGD92636.1 - 0.033 13.9 0.1 1.6 8.4 0.0 3.3 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB Peptidase_M16 PF00675.15 EGD92637.1 - 7.2e-18 64.7 0.0 1.3e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGD92637.1 - 1.5e-13 50.8 0.0 2.5e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Mito_carr PF00153.22 EGD92638.1 - 1.3e-24 85.6 7.3 2.9e-10 39.7 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 EGD92639.1 - 2.6e-100 335.6 0.0 3.5e-100 335.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EGD92639.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Eclosion hormone DSPc PF00782.15 EGD92640.1 - 4.6e-20 71.5 0.0 8.8e-17 60.9 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD92640.1 - 0.0024 17.2 1.0 0.0055 16.0 0.2 2.1 1 1 1 2 2 2 1 Protein-tyrosine phosphatase RRM_5 PF13893.1 EGD92642.1 - 0.076 12.8 0.1 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) M-inducer_phosp PF06617.8 EGD92643.1 - 0.0053 15.8 0.9 0.0063 15.5 0.7 1.1 1 0 0 1 1 1 1 M-phase inducer phosphatase ORC6 PF05460.8 EGD92643.1 - 0.0092 15.1 3.2 0.01 14.9 2.2 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Sds3 PF08598.6 EGD92643.1 - 0.012 15.1 2.7 0.013 14.9 1.9 1.0 1 0 0 1 1 1 0 Sds3-like DUF3899 PF13038.1 EGD92643.1 - 0.016 15.3 0.3 0.019 15.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) RNA_pol_Rpc4 PF05132.9 EGD92643.1 - 0.021 14.7 0.6 0.026 14.4 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 SCHIP-1 PF10148.4 EGD92643.1 - 0.033 13.6 1.2 0.038 13.3 0.9 1.0 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 FAM176 PF14851.1 EGD92643.1 - 0.062 12.9 1.3 0.071 12.7 0.9 1.1 1 0 0 1 1 1 0 FAM176 family HSP90 PF00183.13 EGD92643.1 - 0.068 11.5 5.1 0.079 11.3 3.5 1.1 1 0 0 1 1 1 0 Hsp90 protein PBP1_TM PF14812.1 EGD92643.1 - 0.071 13.4 9.7 0.098 12.9 6.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PEX11 PF05648.9 EGD92643.1 - 0.099 11.8 1.1 0.12 11.5 0.8 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF1777 PF08648.7 EGD92643.1 - 0.11 12.1 13.8 0.13 11.9 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Pap_E4 PF02711.9 EGD92643.1 - 0.14 12.9 2.7 0.17 12.7 1.9 1.2 1 0 0 1 1 1 0 E4 protein OATP PF03137.15 EGD92643.1 - 0.18 9.7 0.5 0.21 9.5 0.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RNA_polI_A34 PF08208.6 EGD92643.1 - 0.2 11.2 9.1 0.22 11.1 6.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Snf7 PF03357.16 EGD92643.1 - 0.22 10.8 7.3 0.25 10.6 5.0 1.1 1 0 0 1 1 1 0 Snf7 FANCI_S4 PF14678.1 EGD92643.1 - 0.33 10.0 3.3 0.45 9.5 2.3 1.1 1 0 0 1 1 1 0 FANCI solenoid 4 CDC45 PF02724.9 EGD92643.1 - 0.46 8.4 3.9 0.44 8.5 2.7 1.0 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 EGD92643.1 - 0.52 10.3 4.3 0.65 10.0 3.0 1.2 1 0 0 1 1 1 0 YqfQ-like protein Mating_C PF12737.2 EGD92643.1 - 0.57 9.0 8.7 0.68 8.7 6.1 1.0 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 DUF3464 PF11947.3 EGD92643.1 - 0.57 9.6 3.3 0.64 9.4 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DDHD PF02862.12 EGD92643.1 - 0.62 9.8 3.0 0.69 9.6 2.1 1.1 1 0 0 1 1 1 0 DDHD domain Nucleoplasmin PF03066.10 EGD92643.1 - 0.66 9.4 4.8 0.83 9.1 3.3 1.1 1 0 0 1 1 1 0 Nucleoplasmin Cas_Csy4 PF09618.5 EGD92643.1 - 0.89 9.3 4.4 0.97 9.2 3.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) DUF3682 PF12446.3 EGD92643.1 - 1.4 9.1 6.9 1.9 8.8 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) U79_P34 PF03064.11 EGD92643.1 - 1.7 8.1 9.1 1.8 8.0 6.3 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Peptidase_S49_N PF08496.5 EGD92643.1 - 1.9 8.2 4.6 2.3 8.0 3.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNase_H2-Ydr279 PF09468.5 EGD92643.1 - 4 6.5 7.7 4.9 6.2 5.3 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Herpes_DNAp_acc PF04929.7 EGD92643.1 - 8.1 5.2 6.9 9.5 5.0 4.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TFIIH_BTF_p62_N PF08567.6 EGD92644.1 - 0.15 11.7 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain E1-E2_ATPase PF00122.15 EGD92645.1 - 6.5e-61 205.2 6.8 6.5e-61 205.2 4.7 1.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EGD92645.1 - 1.3e-13 51.8 0.0 5.3e-10 40.0 0.0 2.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD92645.1 - 6.4e-12 44.7 0.0 1.6e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGD92645.1 - 0.00028 21.1 0.0 0.58 10.2 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD92645.1 - 0.0015 18.1 1.6 0.0024 17.5 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glycos_transf_1 PF00534.15 EGD92646.1 - 3.4e-20 72.1 0.0 6.2e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGD92646.1 - 2.2e-09 37.5 0.0 7.7e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGD92646.1 - 0.00029 21.0 0.0 0.00075 19.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ribonuclease PF00545.15 EGD92648.1 - 2.4e-07 30.7 0.1 3.4e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 ribonuclease DUF3632 PF12311.3 EGD92649.1 - 5.2e-49 166.5 9.5 6.7e-49 166.1 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) RNA_pol_Rpb2_6 PF00562.23 EGD92650.1 - 3.3e-119 398.0 0.0 5.1e-119 397.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGD92650.1 - 1.6e-56 190.4 0.4 6.9e-56 188.3 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGD92650.1 - 7.2e-30 103.8 1.9 3e-29 101.7 1.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EGD92650.1 - 6.3e-27 93.6 0.2 1.6e-26 92.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EGD92650.1 - 2.5e-22 78.4 0.3 1e-21 76.4 0.2 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EGD92650.1 - 1.7e-18 66.1 0.0 4.1e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EGD92650.1 - 8.2e-13 48.1 0.2 2.6e-12 46.5 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 EGD92650.1 - 0.041 12.2 1.5 0.049 11.9 0.1 1.7 2 0 0 2 2 2 0 Baculovirus Y142 protein PUF PF00806.14 EGD92652.1 - 7.5e-57 185.7 8.4 1.1e-07 30.9 0.0 9.0 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat ORC5_C PF14630.1 EGD92653.1 - 7e-79 265.0 0.0 8.9e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EGD92653.1 - 6.4e-15 55.6 0.0 4.3e-14 52.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EGD92653.1 - 6.7e-07 29.1 0.0 0.0064 16.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 EGD92653.1 - 0.00044 20.3 0.0 0.0012 18.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EGD92653.1 - 0.00093 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EGD92653.1 - 0.0041 16.6 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family KAP_NTPase PF07693.9 EGD92653.1 - 0.0058 15.6 0.0 0.012 14.6 0.0 1.5 2 0 0 2 2 2 1 KAP family P-loop domain AAA_30 PF13604.1 EGD92653.1 - 0.0068 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGD92653.1 - 0.0075 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EGD92653.1 - 0.0078 15.7 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 EGD92653.1 - 0.008 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EGD92653.1 - 0.0094 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EGD92653.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGD92653.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGD92653.1 - 0.013 16.2 0.0 0.025 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGD92653.1 - 0.022 14.5 0.0 0.076 12.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EGD92653.1 - 0.044 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 EGD92653.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.4 2 0 0 2 2 1 0 Archaeal ATPase RNA_helicase PF00910.17 EGD92653.1 - 0.092 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Guanylate_kin PF00625.16 EGD92653.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase SMC_N PF02463.14 EGD92653.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 EGD92653.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EGD92653.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA PF00004.24 EGD92653.1 - 0.17 12.0 0.1 0.42 10.8 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGD92653.1 - 0.18 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGD92653.1 - 0.24 10.2 0.0 0.59 8.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain Mak10 PF04112.8 EGD92654.1 - 7.3e-36 122.9 0.0 1.5e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase TMEM101 PF15111.1 EGD92654.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 TMEM101 protein family ATP-synt_Eps PF04627.8 EGD92655.1 - 7.8e-20 70.1 0.3 1e-19 69.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain HTH_AsnC-type PF13404.1 EGD92656.1 - 0.029 13.8 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Cpn60_TCP1 PF00118.19 EGD92657.1 - 3.6e-117 391.9 7.2 4.2e-117 391.7 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 EGD92657.1 - 0.18 11.4 1.6 0.48 10.1 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) Cofilin_ADF PF00241.15 EGD92658.1 - 8.9e-24 83.7 0.0 1.1e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Galanin PF01296.13 EGD92659.1 - 0.025 14.3 0.4 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Galanin COX4 PF02936.9 EGD92660.1 - 3e-49 166.4 0.3 3.7e-49 166.1 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.3 EGD92660.1 - 0.19 12.1 4.1 0.48 10.8 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) DUF1289 PF06945.8 EGD92660.1 - 4.3 6.8 6.1 5.6 6.5 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Alpha-amylase_C PF02806.13 EGD92661.1 - 5.3e-24 84.1 0.1 1.4e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.13 EGD92661.1 - 1.2e-16 60.5 0.1 2.9e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.19 EGD92661.1 - 6.7e-14 52.0 1.7 1.1e-13 51.2 0.4 1.8 2 0 0 2 2 2 1 Alpha amylase, catalytic domain ATP-synt_ab PF00006.20 EGD92662.1 - 7.9e-48 162.7 0.1 4.1e-46 157.1 0.0 2.3 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGD92662.1 - 4e-26 91.7 0.6 7.4e-26 90.8 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGD92662.1 - 8.8e-22 77.1 3.2 2.9e-21 75.4 1.8 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 EGD92662.1 - 0.0012 18.2 0.1 0.03 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGD92662.1 - 0.0027 17.8 0.1 0.13 12.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EGD92662.1 - 0.016 14.4 0.1 0.029 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EGD92662.1 - 0.02 14.5 0.1 0.065 12.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 EGD92662.1 - 0.021 14.5 0.1 1.2 8.8 0.0 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EGD92662.1 - 0.031 13.4 0.1 0.055 12.5 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 EGD92662.1 - 0.032 14.2 0.1 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 EGD92662.1 - 0.067 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EGD92662.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 EGD92662.1 - 0.23 10.2 0.6 0.59 8.9 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain FAD_binding_4 PF01565.18 EGD92664.1 - 3.9e-16 58.7 0.3 8.2e-16 57.7 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD92664.1 - 8.1e-10 38.4 0.2 2.1e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like AAA_2 PF07724.9 EGD92667.1 - 1.6e-38 132.2 0.0 1.9e-37 128.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGD92667.1 - 1e-14 54.8 0.0 2.3e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EGD92667.1 - 1.5e-09 37.5 0.1 5e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EGD92667.1 - 1.5e-06 27.9 0.0 3.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGD92667.1 - 0.00015 21.0 0.1 0.0061 15.7 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EGD92667.1 - 0.0003 20.2 0.0 0.086 12.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 EGD92667.1 - 0.00058 20.0 0.3 0.0082 16.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGD92667.1 - 0.0007 19.0 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EGD92667.1 - 0.00079 20.2 0.1 0.0024 18.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EGD92667.1 - 0.00097 19.1 0.7 0.0029 17.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EGD92667.1 - 0.0027 17.1 0.0 0.0055 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EGD92667.1 - 0.0035 16.9 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGD92667.1 - 0.0067 15.5 0.1 0.098 11.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGD92667.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGD92667.1 - 0.025 14.8 0.1 0.47 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain MCM PF00493.18 EGD92667.1 - 0.026 13.3 0.2 0.083 11.6 0.1 1.7 1 1 0 1 1 1 0 MCM2/3/5 family AAA_33 PF13671.1 EGD92667.1 - 0.034 14.0 0.9 0.38 10.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EGD92667.1 - 0.043 13.9 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EGD92667.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EGD92667.1 - 0.057 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EGD92667.1 - 0.077 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EGD92667.1 - 0.11 12.1 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 EGD92667.1 - 0.58 9.5 2.8 2.6 7.4 0.1 2.5 1 1 1 2 2 2 0 AAA-like domain Chromo PF00385.19 EGD92668.1 - 4.2e-09 35.9 0.1 1.1e-08 34.6 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EGD92668.1 - 0.031 14.1 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Ras PF00071.17 EGD92669.1 - 3.2e-63 211.9 0.2 3.8e-63 211.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD92669.1 - 6.4e-22 78.2 0.3 1.1e-21 77.4 0.1 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EGD92669.1 - 1.7e-13 50.1 0.1 2.2e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGD92669.1 - 3.1e-08 33.5 0.1 5.2e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD92669.1 - 2.9e-05 23.5 0.1 0.0001 21.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGD92669.1 - 4.4e-05 23.6 0.1 0.00014 22.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 EGD92669.1 - 8.5e-05 21.8 0.2 0.00014 21.0 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 EGD92669.1 - 0.0014 17.7 0.0 0.0017 17.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EGD92669.1 - 0.0016 18.3 0.1 0.0052 16.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGD92669.1 - 0.0025 17.0 0.1 0.0052 15.9 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 EGD92669.1 - 0.0033 17.3 0.1 0.045 13.6 0.0 2.2 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 EGD92669.1 - 0.0067 15.6 0.0 0.012 14.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EGD92669.1 - 0.014 15.6 0.1 0.021 15.1 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EGD92669.1 - 0.023 14.2 0.4 0.055 13.0 0.0 1.8 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 EGD92669.1 - 0.023 14.6 0.4 0.05 13.5 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_32 PF13654.1 EGD92669.1 - 0.083 11.5 0.1 0.63 8.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 EGD92669.1 - 0.091 12.0 0.1 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EGD92669.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EGD92669.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 EGD92669.1 - 0.13 12.2 1.2 0.2 11.6 0.9 1.6 1 1 0 1 1 1 0 AAA domain F-box-like PF12937.2 EGD92670.1 - 2.2e-07 30.5 0.8 1.2e-06 28.1 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGD92670.1 - 0.002 17.7 0.1 0.0076 15.8 0.0 2.0 1 0 0 1 1 1 1 F-box domain Brix PF04427.13 EGD92671.1 - 4.2e-32 111.3 0.0 6.4e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Brix domain CDC45 PF02724.9 EGD92671.1 - 0.0049 14.9 3.0 0.0081 14.2 2.1 1.4 1 0 0 1 1 1 1 CDC45-like protein DUF2551 PF10826.3 EGD92671.1 - 0.099 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) DUF1356 PF07092.7 EGD92671.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) RRN3 PF05327.6 EGD92671.1 - 0.43 8.6 4.8 0.64 8.0 3.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TEX19 PF15553.1 EGD92671.1 - 2 8.2 4.6 4.8 7.0 3.2 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 WW PF00397.21 EGD92672.1 - 3.4e-07 30.0 2.7 7.5e-07 28.9 1.9 1.6 1 0 0 1 1 1 1 WW domain Tetraspannin PF00335.15 EGD92673.1 - 0.066 12.4 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF3623 PF12291.3 EGD92674.1 - 0.0095 14.9 1.8 0.016 14.2 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3623) Abp2 PF09441.5 EGD92675.1 - 2.5e-82 275.0 0.1 4.4e-82 274.2 0.1 1.3 1 0 0 1 1 1 1 ARS binding protein 2 ORC6 PF05460.8 EGD92676.1 - 0.0046 16.1 3.4 0.0058 15.7 2.4 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) TMEM171 PF15471.1 EGD92678.1 - 1.3 7.7 7.7 1.8 7.3 5.3 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF3359 PF11839.3 EGD92679.1 - 0.028 14.7 1.0 0.037 14.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) 4F5 PF04419.9 EGD92679.1 - 2.4 8.9 7.2 0.57 10.9 1.3 2.5 1 1 1 2 2 2 0 4F5 protein family Mucin PF01456.12 EGD92681.1 - 0.039 13.7 11.7 0.063 13.0 8.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MAP65_ASE1 PF03999.7 EGD92683.1 - 0.082 11.5 5.9 0.11 11.0 4.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ORC6 PF05460.8 EGD92683.1 - 8.1 5.4 10.8 19 4.2 7.8 1.4 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF829 PF05705.9 EGD92684.1 - 1.5e-48 165.6 0.0 1.8e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) UFD1 PF03152.9 EGD92685.1 - 4.5e-76 253.8 0.0 6.1e-76 253.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EGD92685.1 - 0.022 14.4 0.0 0.19 11.4 0.0 2.1 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 GYF PF02213.11 EGD92686.1 - 5.2e-09 35.5 1.0 1.1e-08 34.5 0.7 1.5 1 0 0 1 1 1 1 GYF domain TIP49 PF06068.8 EGD92687.1 - 3.4e-173 575.9 2.2 4e-173 575.7 1.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EGD92687.1 - 4.7e-08 33.2 0.1 5.4e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGD92687.1 - 9.1e-07 28.1 1.4 0.00028 20.0 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EGD92687.1 - 7e-05 21.8 0.2 0.00012 21.1 0.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EGD92687.1 - 0.00023 21.2 0.0 0.0016 18.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGD92687.1 - 0.0003 20.9 0.0 0.27 11.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EGD92687.1 - 0.0018 17.4 0.8 0.023 13.8 0.2 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGD92687.1 - 0.0075 15.9 0.1 0.5 10.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGD92687.1 - 0.0082 16.0 0.0 4 7.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGD92687.1 - 0.023 14.4 0.1 0.058 13.1 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EGD92687.1 - 0.03 13.7 0.0 8.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 EGD92687.1 - 0.037 13.4 0.1 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EGD92687.1 - 0.075 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.1 EGD92687.1 - 0.1 12.4 0.0 0.64 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain HSBP1 PF06825.7 EGD92688.1 - 2.9e-05 23.5 3.3 0.23 11.0 0.0 4.9 4 0 0 4 4 4 1 Heat shock factor binding protein 1 FlaC_arch PF05377.6 EGD92688.1 - 0.0018 18.1 16.5 0.39 10.6 0.5 6.7 6 2 1 7 7 7 2 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 EGD92688.1 - 0.003 17.3 31.4 0.34 10.7 1.2 5.7 3 2 1 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus HrpB7 PF09486.5 EGD92688.1 - 0.0082 16.0 2.3 0.0082 16.0 1.6 4.2 3 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB7) GAS PF13851.1 EGD92688.1 - 0.0092 15.1 0.5 0.0092 15.1 0.3 4.6 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding AIP3 PF03915.8 EGD92688.1 - 0.053 12.4 33.4 0.063 12.1 6.4 3.7 1 1 2 3 3 3 0 Actin interacting protein 3 DUF2968 PF11180.3 EGD92688.1 - 0.072 12.4 0.2 0.072 12.4 0.2 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2968) MbeD_MobD PF04899.7 EGD92688.1 - 0.09 12.6 11.8 0.31 10.9 0.0 4.8 3 1 1 4 4 4 0 MbeD/MobD like DUF1043 PF06295.7 EGD92688.1 - 0.37 10.4 8.5 1.1 8.9 1.0 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Reo_sigmaC PF04582.7 EGD92688.1 - 0.37 9.9 26.1 1.9 7.6 7.6 4.1 2 1 2 5 5 5 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EGD92688.1 - 0.55 10.0 33.7 0.49 10.2 0.3 5.0 2 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CagA PF03507.8 EGD92688.1 - 0.65 9.8 12.9 0.1 12.4 1.7 4.1 3 3 0 3 3 3 0 CagA exotoxin DUF1664 PF07889.7 EGD92688.1 - 0.78 9.5 25.8 0.19 11.4 0.3 5.4 4 1 1 6 6 6 0 Protein of unknown function (DUF1664) COG2 PF06148.6 EGD92688.1 - 0.92 9.3 20.9 2.4 8.0 1.2 5.5 2 2 3 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Bacillus_HBL PF05791.6 EGD92688.1 - 1.4 8.2 28.6 1.6 8.0 3.2 4.8 4 1 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF948 PF06103.6 EGD92688.1 - 3 7.7 23.8 1.2 8.9 0.3 6.7 5 3 3 8 8 8 0 Bacterial protein of unknown function (DUF948) Cortex-I_coil PF09304.5 EGD92688.1 - 4 7.5 40.8 0.13 12.2 0.7 6.8 2 1 5 7 7 7 0 Cortexillin I, coiled coil DUF3584 PF12128.3 EGD92688.1 - 5.9 4.0 41.3 0.26 8.5 14.4 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) IncA PF04156.9 EGD92688.1 - 6.6 6.2 42.0 0.24 10.9 1.4 5.0 1 1 3 4 4 4 0 IncA protein FSH1 PF03959.8 EGD92689.1 - 2.8e-29 102.0 0.0 3.7e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EGD92689.1 - 0.0023 17.6 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGD92689.1 - 0.012 15.0 0.4 2.3 7.6 0.2 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGD92689.1 - 0.013 15.4 0.0 0.5 10.1 0.0 2.1 1 1 0 2 2 2 0 Alpha/beta hydrolase family Methyltransf_25 PF13649.1 EGD92690.1 - 1.8e-14 53.9 0.0 4.3e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD92690.1 - 5.5e-12 46.2 0.0 1.1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD92690.1 - 5e-09 36.0 0.0 6.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD92690.1 - 5.6e-09 35.7 0.0 7.4e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD92690.1 - 3.2e-08 33.9 0.0 5.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD92690.1 - 8.1e-08 32.6 0.0 1.8e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD92690.1 - 7.4e-06 25.9 0.1 1.6e-05 24.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 EGD92690.1 - 0.0042 16.4 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EGD92690.1 - 0.0049 16.0 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_20 PF12147.3 EGD92690.1 - 0.015 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 EGD92690.1 - 0.015 14.4 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 EGD92690.1 - 0.034 13.5 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase NodS PF05401.6 EGD92690.1 - 0.083 12.2 0.0 0.26 10.6 0.0 1.7 1 1 1 2 2 2 0 Nodulation protein S (NodS) Peptidase_M14 PF00246.19 EGD92691.1 - 1e-72 245.0 0.0 2.6e-72 243.7 0.0 1.6 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EGD92691.1 - 1.6e-09 37.3 0.1 4.2e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase activation peptide AstE_AspA PF04952.9 EGD92691.1 - 0.12 11.2 0.1 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Thioredoxin PF00085.15 EGD92692.1 - 0.0005 19.7 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin SMI1_KNR4 PF09346.5 EGD92693.1 - 1.7e-35 121.8 0.0 2.6e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) DUF4160 PF13711.1 EGD92693.1 - 0.11 12.3 0.5 19 5.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) PNRC PF15365.1 EGD92694.1 - 1.9e-06 27.8 4.1 1.9e-06 27.8 2.9 4.0 4 0 0 4 4 4 2 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 EGD92695.1 - 5.3e-35 119.3 13.2 6.6e-35 119.0 9.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGD92695.1 - 2.9e-17 62.2 10.0 3.8e-17 61.9 7.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EGD92695.1 - 2.7e-07 30.3 12.6 1.6e-06 27.8 8.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGD92695.1 - 0.0021 17.6 11.7 0.037 13.6 8.1 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD92695.1 - 0.0042 16.7 9.6 0.32 10.6 6.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD92695.1 - 0.046 13.7 8.4 0.046 13.7 5.8 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EGD92695.1 - 0.088 12.7 8.8 0.44 10.5 6.2 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 EGD92695.1 - 0.8 9.7 9.5 1.7 8.6 6.6 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGD92695.1 - 1.2 9.2 10.7 1.5 9.0 1.2 2.2 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 EGD92695.1 - 1.7 8.4 6.4 38 4.0 4.4 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EGD92695.1 - 2.7 7.8 11.9 19 5.0 8.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain SPC12 PF06645.8 EGD92696.1 - 7.3e-26 89.7 0.6 8.9e-26 89.5 0.4 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.11 EGD92697.1 - 1.8e-30 105.8 35.6 1.8e-30 105.8 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD92697.1 - 4.3e-15 55.2 8.9 7.2e-15 54.4 6.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter YqcI_YcgG PF08892.6 EGD92698.1 - 6.4e-61 205.7 0.2 7.9e-61 205.3 0.1 1.1 1 0 0 1 1 1 1 YqcI/YcgG family CorA PF01544.13 EGD92699.1 - 3.3e-43 147.7 0.0 4.4e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Mid1 PF12929.2 EGD92700.1 - 2.3e-149 497.7 4.9 2.7e-149 497.5 3.4 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EGD92700.1 - 0.76 10.1 6.0 6.1 7.2 1.8 2.6 2 1 0 2 2 2 0 Fz domain Es2 PF09751.4 EGD92701.1 - 5.8e-110 368.5 12.1 6.9e-110 368.3 8.4 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 RE_LlaMI PF09562.5 EGD92701.1 - 0.084 12.0 0.1 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 LlaMI restriction endonuclease Anophelin PF10731.4 EGD92701.1 - 2.3 8.4 4.6 0.94 9.6 0.9 2.1 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Zn_clus PF00172.13 EGD92705.1 - 1.8e-06 27.7 10.3 3e-06 27.0 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SGL PF08450.7 EGD92706.1 - 1.1e-25 90.5 0.5 9e-24 84.1 0.4 2.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EGD92706.1 - 0.0025 17.7 0.0 0.065 13.2 0.0 3.0 3 1 0 3 3 3 1 Strictosidine synthase Arylesterase PF01731.15 EGD92706.1 - 0.11 12.5 0.0 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 Arylesterase TPR_11 PF13414.1 EGD92707.1 - 3.7e-25 87.3 42.2 3.9e-06 26.4 0.1 11.5 8 3 2 11 11 11 6 TPR repeat TPR_2 PF07719.12 EGD92707.1 - 8.3e-25 84.6 21.6 0.0066 16.2 0.1 12.4 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.23 EGD92707.1 - 1.9e-22 77.8 24.3 0.0011 18.4 0.1 11.6 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_19 PF14559.1 EGD92707.1 - 1.5e-18 66.8 32.6 1.1e-05 25.6 0.0 9.8 9 3 2 11 11 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGD92707.1 - 2.9e-18 65.5 28.8 2.7e-06 27.2 1.4 10.5 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGD92707.1 - 1.3e-17 62.2 21.5 0.035 13.8 0.0 11.4 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_14 PF13428.1 EGD92707.1 - 8e-17 60.2 31.8 0.0014 19.0 0.1 13.0 14 1 1 15 15 13 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGD92707.1 - 3.9e-15 56.0 36.6 0.00016 22.2 0.0 11.0 9 2 3 12 12 12 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGD92707.1 - 2.8e-07 30.2 21.1 0.13 12.5 0.0 11.3 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGD92707.1 - 1.5e-06 28.2 30.7 0.0063 16.9 0.2 12.6 15 0 0 15 15 14 1 Tetratricopeptide repeat Apc3 PF12895.2 EGD92707.1 - 7.2e-05 22.8 21.7 0.53 10.4 0.0 7.8 7 2 0 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGD92707.1 - 0.00019 21.0 30.0 0.31 10.9 0.3 9.7 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 EGD92707.1 - 0.098 13.1 3.7 22 5.8 0.0 4.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGD92707.1 - 0.16 11.8 7.6 4.3 7.2 0.1 4.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EGD92707.1 - 4.8 7.2 20.4 0.25 11.3 0.2 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Acyltransferase PF01553.16 EGD92708.1 - 7.2e-27 93.4 0.0 1.1e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 EGD92709.1 - 1.9e-49 167.9 0.1 2.6e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Myticin-prepro PF10690.4 EGD92710.1 - 0.14 12.2 0.3 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Pkinase PF00069.20 EGD92711.1 - 1.1e-69 234.4 0.0 1.9e-69 233.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92711.1 - 5.6e-51 173.0 0.2 9.5e-51 172.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EGD92711.1 - 2.7e-23 82.1 1.1 1e-22 80.2 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EGD92711.1 - 7.4e-06 25.1 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EGD92711.1 - 0.001 19.2 0.0 0.004 17.3 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Seadorna_VP7 PF07387.6 EGD92711.1 - 0.027 13.2 0.1 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EGD92711.1 - 0.098 12.3 0.2 0.098 12.3 0.2 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family tRNA-synt_2b PF00587.20 EGD92713.1 - 1.2e-67 226.8 0.1 2e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGD92713.1 - 3.7e-19 68.4 0.0 3.7e-19 68.4 0.0 2.9 3 1 0 3 3 3 1 Anticodon binding domain Brix PF04427.13 EGD92714.1 - 4.1e-37 127.6 0.1 6.3e-37 127.0 0.1 1.3 1 0 0 1 1 1 1 Brix domain Ebola_NP PF05505.7 EGD92714.1 - 0.24 9.4 9.3 0.31 9.0 6.4 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Sporozoite_P67 PF05642.6 EGD92714.1 - 0.69 7.7 4.8 0.94 7.2 3.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 EGD92714.1 - 3.5 5.4 23.4 4.8 4.9 16.2 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L1 PF00687.16 EGD92715.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family SET PF00856.23 EGD92716.1 - 8.2e-22 78.2 0.4 8.2e-22 78.2 0.3 3.4 2 2 0 2 2 2 1 SET domain SRI PF08236.6 EGD92716.1 - 2.3e-21 75.5 13.3 8.1e-21 73.7 9.2 2.0 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain DUF3287 PF11690.3 EGD92716.1 - 0.096 12.7 7.0 0.031 14.3 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Pox_H7 PF04787.7 EGD92716.1 - 0.35 10.6 5.8 0.91 9.3 4.0 1.6 1 0 0 1 1 1 0 Late protein H7 Baculo_PEP_C PF04513.7 EGD92718.1 - 4.3e-06 26.5 9.4 0.00023 20.9 1.1 2.0 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Transcrip_act PF04949.8 EGD92718.1 - 0.0002 21.0 0.2 0.0045 16.6 0.0 2.1 1 1 1 2 2 2 1 Transcriptional activator ISG65-75 PF11727.3 EGD92718.1 - 0.00022 20.3 0.5 0.00031 19.8 0.4 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein Spc7 PF08317.6 EGD92718.1 - 0.0012 17.6 1.3 0.0015 17.3 0.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF677 PF05055.7 EGD92718.1 - 0.0027 16.4 0.4 0.0034 16.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) EzrA PF06160.7 EGD92718.1 - 0.0046 15.2 1.7 0.0082 14.3 0.9 1.5 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA NPV_P10 PF05531.7 EGD92718.1 - 0.0055 16.9 4.3 0.015 15.5 1.6 2.6 2 1 0 2 2 1 1 Nucleopolyhedrovirus P10 protein Cortex-I_coil PF09304.5 EGD92718.1 - 0.0092 16.0 0.9 0.021 14.8 0.5 1.6 1 1 1 2 2 2 1 Cortexillin I, coiled coil Filament PF00038.16 EGD92718.1 - 0.0098 15.3 1.2 0.013 14.9 0.8 1.2 1 0 0 1 1 1 1 Intermediate filament protein FlaC_arch PF05377.6 EGD92718.1 - 0.015 15.1 2.2 5.2 7.0 0.0 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4455 PF14643.1 EGD92718.1 - 0.016 13.8 0.2 0.02 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) APG17 PF04108.7 EGD92718.1 - 0.017 13.9 2.3 0.035 12.9 1.4 1.6 1 1 0 1 1 1 0 Autophagy protein Apg17 BLOC1_2 PF10046.4 EGD92718.1 - 0.025 14.7 2.1 0.15 12.2 1.1 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 EGD92718.1 - 0.028 12.9 0.9 0.031 12.7 0.6 1.0 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 EGD92718.1 - 0.031 14.0 0.6 0.066 12.9 0.4 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 EGD92718.1 - 0.031 13.8 0.8 0.046 13.2 0.6 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin PF00804.20 EGD92718.1 - 0.032 14.4 1.5 0.059 13.5 1.0 1.5 1 0 0 1 1 1 0 Syntaxin TelA PF05816.6 EGD92718.1 - 0.037 12.7 2.7 0.49 9.0 0.6 2.2 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) LXG PF04740.7 EGD92718.1 - 0.042 13.6 0.6 6.4 6.5 0.1 2.5 1 1 0 2 2 2 0 LXG domain of WXG superfamily GAS PF13851.1 EGD92718.1 - 0.044 12.9 1.0 0.058 12.5 0.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 EGD92718.1 - 0.044 13.5 2.1 1.1 9.0 0.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.5 EGD92718.1 - 0.045 13.8 3.7 0.079 13.0 1.8 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Transposase_22 PF02994.9 EGD92718.1 - 0.049 12.1 1.2 0.062 11.7 0.8 1.2 1 0 0 1 1 1 0 L1 transposable element P4Ha_N PF08336.6 EGD92718.1 - 0.05 13.4 0.5 1.5 8.6 0.1 2.7 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Tropomyosin_1 PF12718.2 EGD92718.1 - 0.055 13.3 1.1 0.09 12.6 0.8 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF3206 PF11472.3 EGD92718.1 - 0.064 13.0 0.1 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) WEMBL PF05701.6 EGD92718.1 - 0.065 11.6 1.3 0.085 11.3 0.9 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Allexi_40kDa PF05549.6 EGD92718.1 - 0.072 12.3 2.3 0.11 11.7 1.5 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein Filo_VP35 PF02097.10 EGD92718.1 - 0.076 12.1 0.3 0.092 11.9 0.2 1.1 1 0 0 1 1 1 0 Filoviridae VP35 IncA PF04156.9 EGD92718.1 - 0.088 12.4 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 IncA protein Bacillus_HBL PF05791.6 EGD92718.1 - 0.097 12.0 1.6 0.27 10.6 0.8 1.7 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 EGD92718.1 - 0.11 11.6 3.5 0.18 10.9 2.4 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EGD92718.1 - 0.11 11.4 1.3 0.16 10.9 0.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 EGD92718.1 - 0.12 12.1 3.8 0.38 10.5 1.8 2.0 1 1 1 2 2 2 0 Laminin Domain II Spectrin PF00435.16 EGD92718.1 - 0.14 12.4 1.5 6.5 7.0 0.1 2.4 1 1 1 2 2 2 0 Spectrin repeat ApoO PF09769.4 EGD92718.1 - 0.16 11.6 0.8 1 9.0 0.5 2.0 1 1 1 2 2 2 0 Apolipoprotein O FlgN PF05130.7 EGD92718.1 - 0.18 12.0 1.2 0.47 10.6 0.4 1.9 1 1 0 1 1 1 0 FlgN protein Mer2 PF09074.5 EGD92718.1 - 0.18 11.6 2.9 0.73 9.7 1.8 1.8 1 1 1 2 2 2 0 Mer2 PUB PF09409.5 EGD92718.1 - 0.2 11.4 0.7 3.1 7.6 0.2 2.6 2 1 1 3 3 3 0 PUB domain PspA_IM30 PF04012.7 EGD92718.1 - 0.22 10.8 1.5 0.7 9.2 0.6 1.8 1 1 1 2 2 2 0 PspA/IM30 family DUF1664 PF07889.7 EGD92718.1 - 0.25 11.1 4.0 0.92 9.3 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2937 PF11157.3 EGD92718.1 - 0.32 10.3 1.5 6.8 5.9 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2937) DUF948 PF06103.6 EGD92718.1 - 0.94 9.3 3.6 2.1 8.2 0.3 2.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Daxx PF03344.10 EGD92721.1 - 3.5 5.9 15.8 4.3 5.6 11.0 1.1 1 0 0 1 1 1 0 Daxx Family AT_hook PF02178.14 EGD92722.1 - 0.015 14.8 1.6 0.071 12.8 1.1 2.2 1 0 0 1 1 1 0 AT hook motif BAR PF03114.13 EGD92723.1 - 6.3e-44 150.1 2.7 1.4e-43 149.0 1.9 1.5 1 1 0 1 1 1 1 BAR domain DUF1204 PF06721.6 EGD92723.1 - 0.061 12.5 1.3 0.088 12.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) C1_3 PF07649.7 EGD92724.1 - 0.17 11.9 3.7 0.64 10.0 0.5 2.2 2 0 0 2 2 2 0 C1-like domain Pkinase PF00069.20 EGD92725.1 - 1.2e-63 214.6 0.0 1.7e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92725.1 - 2.2e-26 92.5 0.0 3e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD92725.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD92725.1 - 0.015 14.3 0.0 0.041 12.8 0.0 1.7 1 1 1 2 2 2 0 Kinase-like Sybindin PF04099.7 EGD92726.1 - 4.8e-25 87.9 0.0 6e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EGD92726.1 - 0.0012 18.7 0.1 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 EGD92727.1 - 4.1e-59 199.8 0.0 7.3e-59 199.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92727.1 - 8.9e-35 120.0 0.0 8.8e-33 113.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGD92727.1 - 1.2e-09 37.6 0.0 7.6e-08 31.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGD92727.1 - 0.0018 18.0 0.1 0.01 15.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pept_tRNA_hydro PF01195.14 EGD92728.1 - 7.3e-24 84.2 0.0 1.9e-09 37.2 0.0 3.0 3 0 0 3 3 3 3 Peptidyl-tRNA hydrolase DUF2263 PF10021.4 EGD92729.1 - 0.0012 18.8 0.0 0.0056 16.6 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Methyltransf_23 PF13489.1 EGD92730.1 - 2e-12 47.1 0.0 6e-12 45.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD92730.1 - 5e-09 36.7 0.0 2.3e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD92730.1 - 1.2e-06 28.2 0.0 3.6e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD92730.1 - 6.2e-05 23.4 0.0 0.00057 20.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD92730.1 - 0.0014 19.0 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGD92730.1 - 0.0074 16.3 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 EGD92730.1 - 0.017 14.4 0.0 0.097 12.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EGD92730.1 - 0.023 13.7 0.0 0.048 12.7 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_25 PF13649.1 EGD92730.1 - 0.03 14.6 0.0 0.1 12.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EGD92730.1 - 0.061 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) TP6A_N PF04406.9 EGD92731.1 - 8e-13 47.8 0.0 1.4e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase PHZA_PHZB PF03284.8 EGD92731.1 - 0.073 12.1 0.0 5.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Phenazine biosynthesis protein A/B UQ_con PF00179.21 EGD92732.1 - 2.5e-49 166.3 0.0 2.8e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Scramblase PF03803.10 EGD92733.1 - 7.6e-56 188.6 0.0 2.6e-54 183.6 0.0 2.7 1 1 0 1 1 1 1 Scramblase Ribosomal_L27 PF01016.14 EGD92735.1 - 2.4e-31 107.3 0.9 4e-31 106.6 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Rad9_Rad53_bind PF08605.5 EGD92736.1 - 3.5e-17 62.3 0.0 6.7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EGD92736.1 - 1.7e-07 31.3 0.0 6.1e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain tRNA_int_endo PF01974.12 EGD92737.1 - 2.4e-19 68.8 0.1 4.9e-19 67.9 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EGD92737.1 - 7.8e-05 22.1 0.0 0.0034 16.8 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Nop10p PF04135.7 EGD92738.1 - 5.2e-21 74.1 0.2 6.2e-21 73.8 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.6 EGD92739.1 - 1.4e-32 111.2 3.0 3.1e-32 110.2 2.1 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 EGD92739.1 - 0.0046 16.4 0.5 0.0046 16.4 0.3 2.1 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain HypA PF01155.14 EGD92739.1 - 0.042 13.5 0.3 1.5 8.5 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EGD92739.1 - 0.7 9.9 5.6 0.17 11.8 1.1 2.0 2 0 0 2 2 2 0 Zinc ribbon domain YqfQ PF14181.1 EGD92739.1 - 1.4 8.9 9.2 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 YqfQ-like protein EIIBC-GUT_N PF03612.9 EGD92739.1 - 4.6 6.8 7.6 1.2 8.7 0.3 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_M18 PF02127.10 EGD92740.1 - 1e-130 436.1 0.0 1.2e-130 435.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) ABC_tran PF00005.22 EGD92741.1 - 5e-51 172.5 0.0 1.4e-25 90.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EGD92741.1 - 6.2e-24 84.6 47.3 2.7e-16 59.5 17.9 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EGD92741.1 - 2.6e-22 80.1 0.0 0.00012 22.2 0.0 4.5 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EGD92741.1 - 8.4e-10 38.2 1.3 0.00015 21.1 0.1 3.8 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGD92741.1 - 3.5e-09 36.0 8.9 1.6e-05 24.3 0.3 3.4 4 0 0 4 4 3 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGD92741.1 - 3.5e-09 37.2 2.3 0.0016 18.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGD92741.1 - 1.6e-05 24.1 0.2 0.028 13.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGD92741.1 - 0.0002 21.4 0.1 0.78 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 EGD92741.1 - 0.00022 20.4 0.0 0.17 10.8 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EGD92741.1 - 0.0014 18.0 0.1 1.5 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGD92741.1 - 0.0022 17.8 0.2 8.7 6.3 0.1 4.1 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EGD92741.1 - 0.0031 17.0 0.8 0.65 9.5 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EGD92741.1 - 0.0056 16.6 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF4162 PF13732.1 EGD92741.1 - 0.0071 16.8 0.0 0.03 14.8 0.0 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF4162) Zeta_toxin PF06414.7 EGD92741.1 - 0.017 14.1 0.8 3.5 6.6 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin AAA_13 PF13166.1 EGD92741.1 - 0.021 13.3 0.1 0.56 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EGD92741.1 - 0.031 14.2 0.1 8.8 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.17 EGD92741.1 - 0.039 13.3 0.4 7.3 5.9 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EGD92741.1 - 0.051 13.7 0.2 11 6.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGD92741.1 - 0.057 12.8 0.0 7.2 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EGD92741.1 - 0.058 12.8 0.2 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 EGD92741.1 - 0.099 13.1 0.1 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_19 PF13245.1 EGD92741.1 - 0.1 12.3 2.0 12 5.7 0.1 3.1 2 0 0 2 2 2 0 Part of AAA domain G-alpha PF00503.15 EGD92741.1 - 0.28 9.8 0.0 4.9 5.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.1 EGD92741.1 - 0.44 10.4 1.2 29 4.5 0.2 2.6 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EGD92743.1 - 4.1e-36 124.4 32.6 3.5e-35 121.3 16.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGD92743.1 - 1.6 8.7 7.5 0.44 10.6 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) ABC2_membrane PF01061.19 EGD92744.1 - 4.6e-84 280.7 48.4 5.8e-45 153.0 8.5 2.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EGD92744.1 - 1.2e-33 116.2 0.0 8.3e-17 61.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGD92744.1 - 4.7e-25 87.2 0.1 3.5e-21 74.7 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EGD92744.1 - 6.7e-07 29.3 0.0 2.8e-06 27.3 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 EGD92744.1 - 5.7e-06 26.5 0.1 0.09 12.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EGD92744.1 - 7.5e-06 25.8 0.0 0.00051 19.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGD92744.1 - 0.00044 19.7 0.1 0.012 15.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EGD92744.1 - 0.0005 19.5 0.3 0.0046 16.4 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 EGD92744.1 - 0.0013 17.8 53.4 0.0016 17.5 4.5 3.7 2 1 1 3 3 3 2 ABC-2 family transporter protein DUF258 PF03193.11 EGD92744.1 - 0.0016 17.6 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EGD92744.1 - 0.0019 17.6 0.5 0.0043 16.5 0.3 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EGD92744.1 - 0.0021 18.8 0.0 0.043 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGD92744.1 - 0.0028 17.6 0.1 0.038 13.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD92744.1 - 0.0057 16.6 0.2 0.075 13.0 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGD92744.1 - 0.0075 16.4 0.4 0.084 13.0 0.0 2.9 3 1 0 3 3 2 1 AAA domain SMC_N PF02463.14 EGD92744.1 - 0.017 14.3 0.1 0.74 9.0 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EGD92744.1 - 0.019 15.2 0.0 0.23 11.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EGD92744.1 - 0.033 13.9 0.1 4.4 7.1 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 EGD92744.1 - 0.039 13.5 0.9 1.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EGD92744.1 - 0.095 12.1 0.4 1.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EGD92744.1 - 0.19 12.2 0.0 7.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein ATP-grasp_5 PF13549.1 EGD92744.1 - 0.22 10.7 0.0 0.46 9.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Adap_comp_sub PF00928.16 EGD92747.1 - 2.4e-89 298.9 0.0 3.1e-89 298.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGD92747.1 - 1.2e-09 38.0 0.1 2e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EGD92747.1 - 0.069 12.3 0.0 0.24 10.5 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.1 EGD92748.1 - 1.7e-26 92.7 0.0 3e-26 91.8 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EGD92748.1 - 0.00071 20.0 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Sdh_cyt PF01127.17 EGD92750.1 - 1e-23 83.4 3.8 1.4e-23 83.0 2.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NMO PF03060.10 EGD92751.1 - 2.6e-58 197.7 0.0 3.6e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGD92751.1 - 1.8e-06 27.0 0.0 0.00051 19.0 0.4 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGD92751.1 - 0.0049 15.7 0.3 0.0087 14.9 0.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.9 EGD92751.1 - 0.015 14.3 0.3 0.039 12.9 0.0 1.8 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Hydrophobin PF01185.13 EGD92753.1 - 5.2e-09 36.4 12.3 6.8e-09 36.0 8.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin WW PF00397.21 EGD92754.1 - 1.5e-08 34.3 1.9 3.9e-08 33.0 1.3 1.7 1 0 0 1 1 1 1 WW domain Ank_2 PF12796.2 EGD92755.1 - 3.3e-15 56.2 0.9 1.3e-14 54.2 0.5 2.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGD92755.1 - 7.6e-14 50.7 0.4 1.5e-10 40.3 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EGD92755.1 - 3.6e-13 49.2 1.3 3.5e-08 33.4 0.4 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGD92755.1 - 3.9e-13 49.5 1.6 5.7e-08 33.0 0.4 2.7 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD92755.1 - 4.4e-12 44.9 0.5 1.5e-07 30.9 0.1 3.3 4 0 0 4 4 4 2 Ankyrin repeat Glyco_transf_21 PF13506.1 EGD92756.1 - 3.7e-12 45.8 0.0 4.1e-06 26.2 0.0 3.3 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EGD92756.1 - 2.7e-11 43.6 0.0 5.5e-11 42.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 AbfB PF05270.8 EGD92756.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) E1-E2_ATPase PF00122.15 EGD92757.1 - 2.2e-46 157.7 0.8 3.7e-46 157.0 0.6 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGD92757.1 - 7.9e-34 117.9 0.1 1.5e-33 116.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGD92757.1 - 4.4e-18 66.1 0.0 1e-17 64.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD92757.1 - 1.3e-11 44.2 0.1 3.7e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGD92757.1 - 6e-09 35.2 0.0 1.5e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGD92757.1 - 1.4e-05 24.8 1.1 2.2e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Flavodoxin_3 PF12641.2 EGD92757.1 - 0.12 11.8 0.0 0.34 10.3 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain DUF1275 PF06912.6 EGD92757.1 - 0.4 9.8 6.3 0.13 11.4 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1275) DctQ PF04290.7 EGD92757.1 - 2.6 7.8 8.6 1 9.1 1.9 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Cation_ATPase_C PF00689.16 EGD92758.1 - 2.3e-33 115.2 4.7 2.7e-33 115.0 3.3 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF1673 PF07895.6 EGD92758.1 - 0.27 10.7 2.4 0.56 9.7 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) KAT11 PF08214.6 EGD92759.1 - 1.6e-89 300.4 0.0 2e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Cupin_2 PF07883.6 EGD92760.1 - 5.5e-07 28.9 0.0 9.6e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.13 EGD92760.1 - 0.087 12.4 0.1 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Hid1 PF12722.2 EGD92762.1 - 1.1e-277 923.4 0.0 1.9e-277 922.6 0.0 1.4 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EGD92762.1 - 1.3e-73 248.2 0.0 2.1e-73 247.6 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein CDC45 PF02724.9 EGD92764.1 - 0.74 7.7 4.0 0.89 7.5 2.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Vps54 PF07928.7 EGD92766.1 - 1.2e-45 154.9 0.0 3.3e-45 153.5 0.0 1.8 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EGD92766.1 - 1.2e-05 24.4 0.2 3.9e-05 22.7 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 EGD92766.1 - 0.00016 21.5 0.1 0.00064 19.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Cytochrom_B562 PF07361.6 EGD92766.1 - 0.048 14.0 0.4 0.4 11.1 0.3 2.5 2 0 0 2 2 2 0 Cytochrome b562 COG2 PF06148.6 EGD92766.1 - 0.19 11.5 1.7 0.75 9.6 1.2 2.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Pkinase PF00069.20 EGD92768.1 - 1.6e-28 99.5 0.0 2.3e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92768.1 - 1.3e-08 34.2 0.0 0.002 17.2 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGD92768.1 - 0.072 12.8 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family MCM PF00493.18 EGD92769.1 - 2.4e-141 470.3 0.2 3.2e-141 469.9 0.2 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGD92769.1 - 3.2e-18 66.3 0.4 8.3e-18 65.0 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGD92769.1 - 8.6e-07 28.3 0.0 0.00014 21.0 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGD92769.1 - 2.3e-05 24.1 0.0 4.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGD92769.1 - 0.0012 18.4 0.1 0.0048 16.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGD92769.1 - 0.017 14.5 0.1 0.24 10.8 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Lon_2 PF13337.1 EGD92769.1 - 0.05 11.9 0.2 0.5 8.6 0.0 2.0 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease Mg_chelatase_2 PF13335.1 EGD92769.1 - 0.063 13.6 0.6 0.16 12.4 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ECH PF00378.15 EGD92770.1 - 9.9e-37 126.3 0.3 5.4e-25 87.9 0.3 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family PfkB PF00294.19 EGD92771.1 - 1.2e-41 142.8 0.0 2e-41 142.1 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PAN_1 PF00024.21 EGD92772.1 - 7.9e-08 31.9 23.6 0.00045 19.9 3.6 2.8 2 1 1 3 3 3 2 PAN domain PAN_4 PF14295.1 EGD92772.1 - 0.00013 21.5 2.1 0.00013 21.5 1.5 3.7 3 0 0 3 3 3 2 PAN domain PAN_3 PF08277.7 EGD92772.1 - 0.046 13.3 8.3 1.7 8.3 1.8 2.6 2 0 0 2 2 2 0 PAN-like domain DEC-1_N PF04625.8 EGD92773.1 - 6.6 5.2 17.5 7.5 5.1 12.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region 2OG-FeII_Oxy PF03171.15 EGD92774.1 - 0.066 13.5 0.0 0.47 10.7 0.0 2.1 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SDP_N PF12278.3 EGD92775.1 - 0.092 12.3 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Sex determination protein N terminal 7TM_GPCR_Srw PF10324.4 EGD92775.1 - 0.11 11.5 0.6 0.15 11.1 0.4 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF2656 PF10847.3 EGD92775.1 - 0.13 12.1 0.1 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) Filament_head PF04732.9 EGD92776.1 - 1.9 9.2 8.1 0.13 12.9 0.4 2.7 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region Tau95 PF09734.4 EGD92777.1 - 1e-75 254.9 0.1 1.3e-75 254.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit B56 PF01603.15 EGD92778.1 - 2e-171 570.1 5.3 2.4e-171 569.8 3.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Dynamin_N PF00350.18 EGD92778.1 - 0.096 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Dynamin family FAT PF02259.18 EGD92779.1 - 7.7e-74 248.7 12.8 1.5e-73 247.7 8.9 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EGD92779.1 - 4.7e-31 108.0 0.2 2e-30 106.0 0.1 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EGD92779.1 - 3.8e-08 32.6 0.2 1e-07 31.2 0.1 1.8 1 0 0 1 1 1 1 FATC domain DUF572 PF04502.8 EGD92780.1 - 4.4e-72 243.0 13.4 5.4e-72 242.7 9.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 EGD92780.1 - 0.004 17.0 0.2 0.0069 16.2 0.1 1.3 1 0 0 1 1 1 1 Benyvirus 14KDa protein DUF866 PF05907.8 EGD92780.1 - 0.004 16.6 0.4 0.0085 15.6 0.3 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-FCS PF06467.9 EGD92780.1 - 0.044 13.4 3.2 0.22 11.2 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_5 PF13719.1 EGD92780.1 - 0.058 12.9 0.4 9.7 5.8 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EGD92780.1 - 0.067 12.5 3.8 0.75 9.1 1.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.1 EGD92780.1 - 0.084 12.5 0.4 9.4 6.0 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGD92780.1 - 0.11 11.7 0.3 0.52 9.5 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain PMT_C PF11647.3 EGD92780.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 DNA_RNApol_7kD PF03604.8 EGD92780.1 - 0.17 11.3 2.0 12 5.4 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit PcfJ PF14284.1 EGD92780.1 - 0.28 10.6 8.0 0.089 12.2 1.2 2.3 2 0 0 2 2 2 0 PcfJ-like protein TPR_11 PF13414.1 EGD92781.1 - 6.5e-28 96.1 16.6 9e-10 38.0 0.0 8.4 7 1 0 7 7 7 5 TPR repeat TPR_2 PF07719.12 EGD92781.1 - 1.9e-27 92.8 11.9 0.00051 19.7 0.2 11.6 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_1 PF00515.23 EGD92781.1 - 1.1e-24 84.9 8.0 0.00032 20.1 0.6 10.5 11 0 0 11 11 11 5 Tetratricopeptide repeat Apc3 PF12895.2 EGD92781.1 - 7.2e-24 83.7 15.2 1e-19 70.4 1.1 5.4 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGD92781.1 - 9.4e-14 51.1 29.7 4.2e-08 33.0 0.3 9.3 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGD92781.1 - 2.3e-12 47.0 12.9 0.0014 18.8 0.0 7.6 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGD92781.1 - 4.2e-12 46.3 21.7 0.0013 19.3 0.2 8.6 7 2 2 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGD92781.1 - 4.5e-12 44.8 7.2 0.013 15.2 0.0 7.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD92781.1 - 1.9e-11 43.5 16.4 0.24 12.1 0.3 9.2 6 3 4 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGD92781.1 - 4.6e-07 29.1 18.3 2.2 8.2 0.0 9.0 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGD92781.1 - 1.8e-05 24.5 10.0 0.82 10.0 0.0 8.0 9 2 1 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGD92781.1 - 3.3e-05 24.0 9.3 4.3 8.0 0.1 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGD92781.1 - 0.0001 22.1 20.0 0.0026 17.6 0.1 6.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_21 PF09976.4 EGD92781.1 - 0.18 11.7 6.9 51 3.7 0.2 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGD92781.1 - 1 9.9 12.5 0.21 12.1 0.3 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat Trefoil PF00088.13 EGD92781.1 - 7.4 6.2 7.4 0.67 9.6 1.6 1.8 2 0 0 2 2 2 0 Trefoil (P-type) domain Fungal_trans PF04082.13 EGD92782.1 - 2.3e-11 43.0 0.4 5.5e-11 41.8 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD92782.1 - 1.5e-06 27.9 12.2 3.2e-06 26.9 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DHHC PF01529.15 EGD92784.1 - 2.7e-25 88.7 6.9 2.7e-25 88.7 4.8 2.3 2 1 1 3 3 3 1 DHHC palmitoyltransferase Glyco_hydro_17 PF00332.13 EGD92786.1 - 1.8e-08 33.7 1.4 0.00013 21.1 0.4 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 SRR1 PF07985.7 EGD92788.1 - 4.3e-11 42.5 0.1 3.2e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 SRR1 RRP7 PF12923.2 EGD92788.1 - 0.051 13.6 0.9 0.097 12.6 0.1 1.8 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) Abhydrolase_6 PF12697.2 EGD92790.1 - 1.6e-24 87.0 2.8 4.6e-24 85.5 1.9 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD92790.1 - 2.3e-10 40.4 0.6 6.3e-10 39.0 0.4 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD92790.1 - 5.8e-10 39.1 0.1 6.7e-09 35.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGD92790.1 - 4.4e-07 29.6 0.0 1.2e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EGD92790.1 - 0.012 14.4 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 EGD92790.1 - 0.032 13.1 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.15 EGD92790.1 - 0.043 13.2 0.1 0.13 11.6 0.1 1.7 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 EGD92790.1 - 0.045 12.9 0.3 0.071 12.3 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ycf1 PF05758.7 EGD92791.1 - 0.019 12.7 6.4 0.027 12.2 4.4 1.1 1 0 0 1 1 1 0 Ycf1 Band_3_cyto PF07565.8 EGD92791.1 - 0.066 12.7 12.4 0.18 11.2 8.6 1.7 1 0 0 1 1 1 0 Band 3 cytoplasmic domain zf-DHHC PF01529.15 EGD92791.1 - 0.11 11.9 0.7 0.22 10.8 0.5 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase SAPS PF04499.10 EGD92791.1 - 0.48 8.9 11.7 1.4 7.4 8.1 1.7 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Otopetrin PF03189.8 EGD92791.1 - 1.1 8.1 1.3 1.5 7.7 0.9 1.1 1 0 0 1 1 1 0 Otopetrin NARP1 PF12569.3 EGD92791.1 - 1.8 7.2 15.1 2.9 6.5 10.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 LMBR1 PF04791.11 EGD92791.1 - 2 6.8 2.6 3 6.3 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FLO_LFY PF01698.11 EGD92791.1 - 2.7 6.7 14.1 8.7 5.0 9.8 1.8 1 0 0 1 1 1 0 Floricaula / Leafy protein YhhN PF07947.9 EGD92792.1 - 8.1e-42 142.6 3.4 1.2e-41 142.1 2.4 1.2 1 0 0 1 1 1 1 YhhN-like protein BioY PF02632.9 EGD92792.1 - 4.5 6.9 7.8 90 2.6 2.9 3.2 2 1 0 2 2 2 0 BioY family MFS_1 PF07690.11 EGD92793.1 - 5.8e-45 153.5 26.2 5.8e-45 153.5 18.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD92793.1 - 5.7e-10 38.3 7.7 5.7e-10 38.3 5.4 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EGD92793.1 - 0.011 13.7 0.6 0.011 13.7 0.4 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3353 PF11833.3 EGD92793.1 - 0.13 11.7 6.2 0.025 14.0 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) MFS_1_like PF12832.2 EGD92793.1 - 0.13 12.0 5.0 2.3 8.0 0.0 3.1 3 1 0 3 3 3 0 MFS_1 like family eIF-5a PF01287.15 EGD92794.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Zip PF02535.17 EGD92794.1 - 2.5 7.0 8.5 3 6.7 0.6 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter F-box-like_2 PF13013.1 EGD92795.1 - 0.023 14.4 0.4 0.065 12.9 0.3 1.8 1 1 0 1 1 1 0 F-box-like domain PHD PF00628.24 EGD92796.1 - 6.9e-10 38.4 2.3 6.9e-10 38.4 1.6 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EGD92796.1 - 0.0047 16.2 2.4 0.0075 15.5 1.7 1.3 1 0 0 1 1 1 1 PHD-finger Macoilin PF09726.4 EGD92797.1 - 0.18 10.0 6.4 0.21 9.8 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein BAF1_ABF1 PF04684.8 EGD92797.1 - 9.3 4.9 29.8 15 4.3 20.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MARVEL PF01284.18 EGD92798.1 - 1.6e-10 40.9 3.8 2.5e-10 40.3 2.6 1.3 1 1 0 1 1 1 1 Membrane-associating domain Dispanin PF04505.7 EGD92798.1 - 0.15 11.6 0.1 0.15 11.6 0.1 1.9 2 0 0 2 2 2 0 Interferon-induced transmembrane protein DUF1752 PF08550.5 EGD92799.1 - 4.5e-10 38.9 3.4 8.8e-10 37.9 2.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) rRNA_methylase PF06962.7 EGD92799.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative rRNA methylase adh_short_C2 PF13561.1 EGD92800.1 - 3.2e-26 92.5 0.0 4.1e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD92800.1 - 6.2e-20 71.7 0.1 9.2e-20 71.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD92800.1 - 6.8e-11 42.1 0.1 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD92800.1 - 0.0097 15.3 0.1 0.036 13.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CPSase_L_D2 PF02786.12 EGD92801.1 - 8.8e-74 247.3 0.0 1.3e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EGD92801.1 - 1.1e-35 121.7 0.0 2.4e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EGD92801.1 - 6.7e-34 116.3 0.0 2.1e-33 114.7 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EGD92801.1 - 1.2e-18 67.4 0.1 4.8e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EGD92801.1 - 4.5e-16 58.2 2.1 1.3e-15 56.8 1.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EGD92801.1 - 1.7e-12 46.7 0.0 2.9e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EGD92801.1 - 8.5e-10 38.3 0.0 2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EGD92801.1 - 5.7e-07 29.0 0.1 0.016 14.9 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EGD92801.1 - 6.7e-05 22.8 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EGD92801.1 - 0.0015 18.8 0.7 0.25 11.7 0.0 3.0 3 0 0 3 3 3 1 HlyD family secretion protein GARS_A PF01071.14 EGD92801.1 - 0.0032 17.0 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 EGD92801.1 - 0.0094 15.4 0.0 0.038 13.4 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GCV_H PF01597.14 EGD92801.1 - 0.013 15.1 0.4 0.034 13.8 0.1 1.7 2 0 0 2 2 1 0 Glycine cleavage H-protein HlyD PF00529.15 EGD92801.1 - 0.036 13.3 0.6 2.1 7.5 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein ATPgrasp_ST PF14397.1 EGD92801.1 - 0.074 12.1 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Acyl-CoA_dh_1 PF00441.19 EGD92803.1 - 7.1e-41 139.7 0.5 1.6e-40 138.6 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGD92803.1 - 9.5e-35 119.5 0.1 2.2e-34 118.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGD92803.1 - 3.4e-20 71.2 0.3 1e-19 69.7 0.1 1.9 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGD92803.1 - 2.3e-16 60.2 0.1 4.8e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EGD92803.1 - 0.0013 18.2 0.7 0.0052 16.1 0.5 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.17 EGD92804.1 - 3.8e-144 480.7 0.0 4.9e-144 480.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EGD92804.1 - 0.023 13.8 0.0 2.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Ras PF00071.17 EGD92805.1 - 3.3e-45 153.3 0.0 2.2e-24 85.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EGD92805.1 - 9e-16 58.4 0.0 3.9e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 EGD92805.1 - 9e-07 28.2 0.0 0.0024 17.1 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGD92805.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGD92805.1 - 0.0052 16.9 0.1 0.11 12.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EGD92805.1 - 0.0074 15.7 0.0 0.34 10.3 0.0 2.7 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EGD92805.1 - 0.014 15.3 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 EGD92805.1 - 0.05 12.9 0.0 0.27 10.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EGD92805.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Abhydro_lipase PF04083.11 EGD92807.1 - 2.9e-24 84.1 0.3 6.2e-24 83.1 0.1 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EGD92807.1 - 9.5e-19 67.8 0.4 1.5e-18 67.2 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGD92807.1 - 1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD92807.1 - 1.1e-05 25.2 0.0 5.5e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGD92807.1 - 0.00013 21.5 0.1 0.0049 16.3 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EGD92807.1 - 0.044 13.2 0.1 8.6 5.7 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.4 EGD92808.1 - 5.6e-27 93.5 5.9 7.1e-27 93.2 4.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EGD92808.1 - 0.013 15.2 4.7 1.4 8.6 0.4 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PAN_3 PF08277.7 EGD92808.1 - 0.017 14.7 0.3 0.033 13.8 0.2 1.4 1 0 0 1 1 1 0 PAN-like domain COBRA PF04833.10 EGD92808.1 - 0.06 13.1 0.2 0.061 13.0 0.1 1.1 1 0 0 1 1 1 0 COBRA-like protein DDOST_48kD PF03345.9 EGD92809.1 - 8.3e-163 541.8 0.0 9.5e-163 541.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta NADHdh_A3 PF14987.1 EGD92810.1 - 0.038 13.8 0.2 0.045 13.6 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Myc_N PF01056.13 EGD92812.1 - 0.00013 21.2 3.0 0.056 12.6 0.1 2.2 2 0 0 2 2 2 2 Myc amino-terminal region Nucleoplasmin PF03066.10 EGD92812.1 - 0.046 13.2 16.1 0.66 9.4 0.9 2.1 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 EGD92812.1 - 0.17 11.4 11.5 0.16 11.6 2.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region FAM176 PF14851.1 EGD92812.1 - 0.2 11.3 9.4 0.37 10.4 1.6 2.2 2 0 0 2 2 2 0 FAM176 family LAT PF15234.1 EGD92812.1 - 0.55 9.6 5.4 5.9 6.2 0.1 2.2 2 0 0 2 2 2 0 Linker for activation of T-cells PBP1_TM PF14812.1 EGD92812.1 - 0.7 10.2 27.6 0.97 9.7 1.6 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GOLD_2 PF13897.1 EGD92812.1 - 1.3 9.2 4.2 9.7 6.4 0.2 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF3245 PF11595.3 EGD92812.1 - 6.4 7.0 15.6 5.5 7.2 6.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Bd3614_N PF14442.1 EGD92812.1 - 7.1 6.6 9.1 3.9 7.4 3.3 2.1 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal GST_C_2 PF13410.1 EGD92813.1 - 6.9e-08 32.2 0.5 1.9e-07 30.8 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGD92813.1 - 1.8e-07 31.0 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGD92813.1 - 0.00015 21.8 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2306 PF10067.4 EGD92816.1 - 1.5e-14 53.9 7.7 4.9e-14 52.2 2.1 2.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF420 PF04238.7 EGD92816.1 - 0.0045 16.9 0.4 0.0045 16.9 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF420) RDD PF06271.7 EGD92816.1 - 2.1 8.2 11.7 0.15 11.9 2.6 2.4 1 1 2 3 3 3 0 RDD family Sugar_tr PF00083.19 EGD92817.1 - 2.4e-79 267.0 23.9 2.8e-79 266.8 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD92817.1 - 3e-28 98.5 38.2 2.4e-24 85.7 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 EGD92819.1 - 3.3e-67 225.0 0.0 1.1e-32 113.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGD92819.1 - 8.3e-35 120.5 47.7 4.5e-20 72.1 7.2 5.1 4 1 1 5 5 5 4 ABC transporter transmembrane region SMC_N PF02463.14 EGD92819.1 - 4.9e-14 52.0 0.0 7.6e-05 22.0 0.0 3.5 1 1 2 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD92819.1 - 1.4e-11 44.9 2.5 0.011 15.7 0.2 4.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGD92819.1 - 1.8e-08 33.7 0.1 0.00035 20.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EGD92819.1 - 6.9e-08 31.4 2.9 0.0035 16.0 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EGD92819.1 - 2.8e-07 31.3 0.1 0.032 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGD92819.1 - 1.3e-06 28.5 1.8 0.009 16.0 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGD92819.1 - 1.8e-05 24.0 0.0 0.15 11.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGD92819.1 - 4.7e-05 22.8 0.4 0.23 10.8 0.0 3.2 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 EGD92819.1 - 9.3e-05 22.5 2.5 0.58 10.3 0.1 3.8 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGD92819.1 - 0.00054 19.8 2.6 0.52 10.2 0.2 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EGD92819.1 - 0.00073 19.8 0.0 1.3 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGD92819.1 - 0.001 18.9 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EGD92819.1 - 0.0017 17.8 3.5 4.6 6.5 0.5 4.4 3 1 2 5 5 5 1 AAA-like domain AAA_30 PF13604.1 EGD92819.1 - 0.0019 17.8 2.4 3.1 7.3 0.2 3.9 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EGD92819.1 - 0.0027 17.6 0.0 5.6 6.8 0.0 3.9 5 0 0 5 5 4 0 AAA domain AAA_5 PF07728.9 EGD92819.1 - 0.0045 16.7 0.1 1.7 8.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EGD92819.1 - 0.0063 16.4 0.7 1 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EGD92819.1 - 0.0092 16.3 0.0 0.55 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EGD92819.1 - 0.0098 15.7 0.9 0.22 11.2 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 G-alpha PF00503.15 EGD92819.1 - 0.032 12.9 0.1 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit DUF815 PF05673.8 EGD92819.1 - 0.035 13.0 0.0 2.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.9 EGD92819.1 - 0.078 12.6 0.1 14 5.4 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EGD92819.1 - 0.11 12.6 0.7 7.7 6.7 0.0 2.9 3 0 0 3 3 2 0 RNA helicase DUF3767 PF12597.3 EGD92819.1 - 0.23 11.1 0.1 0.51 10.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) AAA_15 PF13175.1 EGD92819.1 - 0.27 10.2 0.0 14 4.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EGD92819.1 - 0.3 10.1 2.0 5.1 6.1 0.0 3.1 4 0 0 4 4 4 0 Zeta toxin Glycoprotein_B PF00606.13 EGD92819.1 - 0.88 7.5 1.6 0.89 7.5 0.2 1.6 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B MMR_HSR1 PF01926.18 EGD92819.1 - 0.95 9.4 3.5 14 5.7 0.1 3.0 2 2 0 2 2 2 0 50S ribosome-binding GTPase ADH_N PF08240.7 EGD92820.1 - 9.6e-28 96.1 6.1 1.8e-27 95.2 4.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD92820.1 - 1.7e-13 50.2 0.0 2.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGD92820.1 - 0.00035 19.7 0.1 0.00058 19.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EGD92820.1 - 0.0018 17.9 0.1 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.1 EGD92820.1 - 0.061 14.2 0.0 0.11 13.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GCC2_GCC3 PF07699.8 EGD92820.1 - 0.076 12.6 0.8 0.35 10.4 0.5 2.0 2 0 0 2 2 2 0 GCC2 and GCC3 Mito_carr PF00153.22 EGD92821.1 - 2.5e-43 145.7 9.5 4.2e-17 61.6 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ferric_reduct PF01794.14 EGD92822.1 - 5.2e-17 62.1 13.3 5.2e-17 62.1 9.2 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGD92822.1 - 8.2e-15 54.5 0.0 1.9e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EGD92822.1 - 4.4e-13 49.4 0.0 7.2e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EGD92822.1 - 0.0053 16.8 0.0 0.0098 16.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGD92822.1 - 0.027 15.0 0.0 1.1 9.8 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Host_attach PF10116.4 EGD92822.1 - 0.083 13.1 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein required for attachment to host cells MadL PF03817.8 EGD92822.1 - 0.5 10.2 4.9 12 5.7 0.3 2.7 2 1 0 3 3 3 0 Malonate transporter MadL subunit ABC1 PF03109.11 EGD92823.1 - 2.5e-20 72.6 0.1 7.3e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 EGD92823.1 - 0.0048 16.6 0.5 0.037 13.7 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family IMS PF00817.15 EGD92824.1 - 1.8e-36 125.1 0.0 2.4e-35 121.5 0.0 2.2 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGD92824.1 - 3.8e-12 46.2 0.0 6.2e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Ribosomal_L37 PF08561.5 EGD92827.1 - 0.29 10.7 2.4 0.71 9.4 1.7 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 WSC PF01822.14 EGD92828.1 - 1.6e-09 37.5 9.1 1.6e-09 37.5 6.3 1.9 2 0 0 2 2 2 1 WSC domain FixQ PF05545.6 EGD92828.1 - 2.7e-05 23.7 0.1 2.7e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Cbb3-type cytochrome oxidase component FixQ TMEM154 PF15102.1 EGD92828.1 - 0.00025 20.7 0.1 0.00044 19.9 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family Mucin PF01456.12 EGD92828.1 - 0.031 14.0 16.5 0.066 12.9 11.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Transp_cyt_pur PF02133.10 EGD92829.1 - 6.6e-26 90.8 32.4 6.6e-26 90.8 22.4 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PRP38 PF03371.10 EGD92831.1 - 5e-67 224.8 0.0 6.1e-67 224.5 0.0 1.1 1 0 0 1 1 1 1 PRP38 family WD40 PF00400.27 EGD92833.1 - 3.5e-20 71.0 9.4 0.0014 18.4 0.0 7.1 8 0 0 8 8 8 5 WD domain, G-beta repeat Trypan_PARP PF05887.6 EGD92833.1 - 0.87 9.3 16.4 0.079 12.7 3.6 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) AAA_12 PF13087.1 EGD92834.1 - 6.2e-38 130.1 0.0 1e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGD92834.1 - 4.4e-24 85.3 0.0 1.5e-23 83.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGD92834.1 - 1.9e-10 40.3 0.0 4.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGD92834.1 - 2.5e-09 37.0 0.0 2.6e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EGD92834.1 - 4.7e-07 29.5 0.1 0.00035 20.1 0.0 3.4 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EGD92834.1 - 0.00069 19.5 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EGD92834.1 - 0.0021 17.3 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 EGD92834.1 - 0.0063 15.5 0.2 0.17 10.7 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EGD92834.1 - 0.01 15.3 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD_C_2 PF13538.1 EGD92834.1 - 0.077 13.1 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ABC_tran PF00005.22 EGD92835.1 - 1.7e-56 190.3 0.2 5.6e-31 107.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGD92835.1 - 4.1e-44 151.0 26.6 2e-25 89.7 8.2 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EGD92835.1 - 9.3e-09 35.6 3.0 0.041 13.8 0.0 4.3 5 0 0 5 5 5 2 AAA domain AAA_25 PF13481.1 EGD92835.1 - 1.6e-07 30.9 0.1 0.013 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGD92835.1 - 3.9e-07 29.5 9.6 0.008 15.4 0.3 4.7 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGD92835.1 - 2.2e-06 28.1 6.0 0.00014 22.2 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EGD92835.1 - 5.6e-06 26.0 0.3 0.67 9.3 0.0 3.4 3 0 0 3 3 3 2 AAA-like domain DUF258 PF03193.11 EGD92835.1 - 2.6e-05 23.4 0.2 0.22 10.7 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGD92835.1 - 3.5e-05 23.2 0.9 0.33 10.5 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGD92835.1 - 8.6e-05 22.4 0.1 0.15 12.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EGD92835.1 - 0.00028 20.0 0.6 0.11 11.5 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin T2SE PF00437.15 EGD92835.1 - 0.0004 19.3 0.1 0.015 14.2 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 EGD92835.1 - 0.00041 20.2 1.3 0.015 15.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_16 PF13191.1 EGD92835.1 - 0.001 19.0 2.1 1.1 9.2 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EGD92835.1 - 0.0011 19.4 0.1 2.9 8.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EGD92835.1 - 0.0012 19.6 0.1 4.4 8.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGD92835.1 - 0.0021 18.1 0.6 4.8 7.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EGD92835.1 - 0.0022 17.4 0.1 0.62 9.5 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EGD92835.1 - 0.0043 17.3 1.8 2.6 8.3 0.0 3.2 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 EGD92835.1 - 0.0072 16.0 0.3 8.3 6.1 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EGD92835.1 - 0.0074 15.7 1.1 1.9 7.9 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA PF00004.24 EGD92835.1 - 0.014 15.5 0.4 2.4 8.3 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 EGD92835.1 - 0.032 13.7 0.3 3.2 7.1 0.0 2.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 EGD92835.1 - 0.05 13.4 1.9 3.9 7.2 0.0 3.2 3 0 0 3 3 3 0 Dynamin family UPF0079 PF02367.12 EGD92835.1 - 0.11 12.0 1.1 10 5.7 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 EGD92835.1 - 0.13 12.0 0.0 12 5.6 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Guanylate_kin PF00625.16 EGD92835.1 - 0.15 11.4 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase DUF2075 PF09848.4 EGD92835.1 - 0.3 10.0 0.5 18 4.1 0.0 2.5 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EGD92835.1 - 0.31 10.6 3.0 3.5 7.2 0.2 2.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 EGD92835.1 - 0.82 9.0 2.8 1.9 7.8 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_M36 PF02128.10 EGD92836.1 - 4.7e-160 532.5 0.7 6e-160 532.1 0.5 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGD92836.1 - 1.1e-12 47.2 4.0 2.6e-12 45.9 1.6 2.5 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EGD92836.1 - 7e-05 22.6 0.0 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Colicin_M PF14859.1 EGD92836.1 - 0.021 13.7 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Colicin M Peptidase_MA_2 PF13485.1 EGD92836.1 - 0.079 13.0 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily UQ_con PF00179.21 EGD92837.1 - 1e-39 135.1 0.0 1.3e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD92837.1 - 0.0049 16.6 0.0 0.021 14.5 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGD92837.1 - 0.01 15.6 0.1 0.028 14.3 0.1 1.7 1 1 1 2 2 2 0 RWD domain Bax1-I PF01027.15 EGD92838.1 - 7.6e-53 179.1 29.0 9e-53 178.9 20.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Lysis_S PF04971.7 EGD92838.1 - 0.12 12.0 1.9 0.4 10.4 1.3 1.9 1 0 0 1 1 1 0 Lysis protein S Orbi_NS3 PF01616.11 EGD92838.1 - 0.18 10.7 2.4 0.68 8.8 0.3 2.2 2 0 0 2 2 2 0 Orbivirus NS3 Myc_target_1 PF15179.1 EGD92838.1 - 0.3 10.6 0.1 0.3 10.6 0.1 1.8 2 0 0 2 2 2 0 Myc target protein 1 7TMR-DISM_7TM PF07695.6 EGD92838.1 - 0.73 9.4 27.7 2.8 7.5 9.8 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Aa_trans PF01490.13 EGD92839.1 - 8.4e-88 294.5 17.2 1.3e-87 293.9 11.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.5 EGD92839.1 - 0.018 13.1 3.8 0.032 12.2 2.7 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Glyco_hydro_75 PF07335.6 EGD92840.1 - 8.3e-43 145.9 0.1 1.1e-42 145.6 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF1620 PF07774.8 EGD92841.1 - 2.3e-73 246.0 0.0 4e-73 245.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EGD92841.1 - 2e-15 56.9 13.8 8.8e-14 51.5 2.0 2.8 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 EGD92841.1 - 2.9e-07 29.6 4.5 1.1 8.8 0.0 5.7 5 0 0 5 5 5 3 PQQ enzyme repeat AT_hook PF02178.14 EGD92842.1 - 4.6e-07 28.7 65.7 0.053 13.2 1.1 6.7 6 0 0 6 6 6 6 AT hook motif CRAL_TRIO PF00650.15 EGD92843.1 - 4.9e-24 84.6 0.0 6.9e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGD92843.1 - 8.2e-09 35.4 0.0 1.9e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SNase PF00565.12 EGD92844.1 - 1.7e-80 266.3 0.1 5.5e-26 90.9 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EGD92844.1 - 2.2e-24 85.6 0.0 8.7e-24 83.6 0.0 2.0 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 EGD92844.1 - 0.00011 21.3 0.0 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF3297 PF11730.3 EGD92844.1 - 0.032 13.9 0.1 0.12 12.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) Fungal_trans PF04082.13 EGD92845.1 - 5.7e-27 94.2 0.4 1.2e-26 93.2 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD92845.1 - 1.8e-05 24.5 8.2 1.8e-05 24.5 5.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EGD92845.1 - 1.3 7.1 8.6 1.9 6.6 5.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sod_Cu PF00080.15 EGD92847.1 - 1.5e-44 151.5 5.3 1.8e-44 151.3 3.7 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Transaldolase PF00923.14 EGD92848.1 - 3.2e-95 318.5 0.1 3.6e-95 318.3 0.1 1.0 1 0 0 1 1 1 1 Transaldolase Beach PF02138.13 EGD92849.1 - 4.4e-107 357.5 0.0 7.8e-107 356.7 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EGD92849.1 - 3.6e-12 45.6 3.0 2e-05 24.2 0.0 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat PH_BEACH PF14844.1 EGD92849.1 - 4.5e-11 42.5 0.1 4.5e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 EGD92849.1 - 2e-06 28.1 0.0 4.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_S8 PF00082.17 EGD92850.1 - 5.4e-53 179.9 9.0 8.2e-53 179.3 6.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD92850.1 - 1.1e-20 73.9 0.3 2.4e-20 72.8 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Daxx PF03344.10 EGD92851.1 - 0.12 10.7 8.7 0.15 10.4 6.0 1.1 1 0 0 1 1 1 0 Daxx Family COPI_C PF06957.6 EGD92851.1 - 0.29 9.6 2.0 0.34 9.4 1.4 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus VID27 PF08553.5 EGD92851.1 - 1 7.4 6.8 1.2 7.2 4.7 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 EGD92851.1 - 1.2 6.9 6.3 1.3 6.8 4.4 1.0 1 0 0 1 1 1 0 Nop14-like family Patatin PF01734.17 EGD92852.1 - 0.11 12.4 0.1 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Patatin-like phospholipase FKBP_C PF00254.23 EGD92856.1 - 1.6e-10 40.8 0.0 4.3e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF544 PF04424.8 EGD92858.1 - 8e-11 41.8 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Gcd10p PF04189.8 EGD92859.1 - 4.3e-88 295.3 0.0 7e-88 294.6 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family Heme_oxygenase PF01126.15 EGD92862.1 - 0.087 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Heme oxygenase CorA PF01544.13 EGD92863.1 - 0.0024 16.9 1.1 0.0024 16.9 0.8 1.9 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein NmrA PF05368.8 EGD92864.1 - 1.9e-52 177.8 0.0 2.5e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD92864.1 - 4.5e-12 46.3 0.0 6.4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGD92864.1 - 1.4e-06 27.2 0.1 1.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EGD92864.1 - 0.0093 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AIG1 PF04548.11 EGD92864.1 - 0.043 12.9 0.1 0.068 12.2 0.1 1.3 1 0 0 1 1 1 0 AIG1 family Myb_DNA-binding PF00249.26 EGD92866.1 - 8.1e-16 57.8 0.0 4.9e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD92866.1 - 2.4e-05 24.3 0.0 0.038 14.1 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain DS PF01916.12 EGD92868.1 - 5e-143 475.6 0.0 5.8e-143 475.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EGD92868.1 - 0.11 11.6 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Carbamoyltransferase Pkinase PF00069.20 EGD92869.1 - 0.077 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain zf-C3HC4_3 PF13920.1 EGD92870.1 - 1.2e-10 40.8 11.4 2.2e-10 40.0 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MORN PF02493.15 EGD92870.1 - 3.4e-06 26.4 23.6 0.023 14.4 3.3 4.6 4 0 0 4 4 4 3 MORN repeat zf-C3HC4_2 PF13923.1 EGD92870.1 - 0.00087 19.2 11.5 0.00098 19.1 6.5 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD92870.1 - 0.2 11.3 12.2 0.41 10.4 8.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF4356 PF14266.1 EGD92870.1 - 0.35 9.2 0.0 0.56 8.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4356) Pkinase PF00069.20 EGD92871.1 - 0.069 12.2 0.0 0.078 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain Abhydrolase_6 PF12697.2 EGD92872.1 - 7.5e-17 61.9 0.5 1e-16 61.5 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD92872.1 - 1.1e-07 31.6 0.0 2.4e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD92872.1 - 1.7e-06 27.7 0.1 5.7e-06 26.0 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold EHN PF06441.7 EGD92872.1 - 0.053 13.4 0.1 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Epoxide hydrolase N terminus HsbA PF12296.3 EGD92874.1 - 2e-33 114.8 6.2 2.1e-33 114.8 3.3 1.7 1 1 1 2 2 2 1 Hydrophobic surface binding protein A Talin_middle PF09141.5 EGD92874.1 - 0.017 14.8 3.3 0.035 13.7 2.3 1.5 1 1 0 1 1 1 0 Talin, middle domain DUF3216 PF11505.3 EGD92874.1 - 0.044 13.5 0.1 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) DUF4179 PF13786.1 EGD92874.1 - 0.072 13.3 1.2 0.18 12.0 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Phage_GP20 PF06810.6 EGD92874.1 - 0.16 11.4 1.9 0.79 9.1 0.1 2.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 PIG-P PF08510.7 EGD92875.1 - 2.8e-40 136.8 1.4 9.5e-40 135.1 0.1 2.2 2 0 0 2 2 2 1 PIG-P CDC45 PF02724.9 EGD92875.1 - 0.0048 15.0 0.1 0.0066 14.5 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein DPM2 PF07297.7 EGD92875.1 - 2.2 8.6 8.9 4.4 7.6 6.2 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) XPA_C PF05181.7 EGD92876.1 - 1.3e-29 101.5 2.5 3.5e-29 100.1 1.7 1.8 1 0 0 1 1 1 1 XPA protein C-terminus YhfH PF14149.1 EGD92876.1 - 0.015 15.0 6.5 0.25 11.1 0.1 2.8 3 0 0 3 3 3 0 YhfH-like protein DUF2406 PF10295.4 EGD92876.1 - 0.037 14.5 0.1 0.12 12.8 0.1 2.0 1 0 0 1 1 1 0 Uncharacterised protein (DUF2406) OrfB_Zn_ribbon PF07282.6 EGD92876.1 - 1.6 8.4 6.1 24 4.6 0.0 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Striatin PF08232.7 EGD92877.1 - 5e-44 149.8 3.0 5e-44 149.8 2.1 2.4 2 1 0 2 2 2 1 Striatin family WD40 PF00400.27 EGD92877.1 - 1.3e-32 110.5 18.1 3.1e-06 26.8 0.0 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGD92877.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGD92877.1 - 0.13 10.5 0.0 0.28 9.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain PAT1 PF09770.4 EGD92877.1 - 0.68 8.1 24.1 0.94 7.6 16.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Blt1 PF12754.2 EGD92878.1 - 5.6e-52 177.2 0.0 6.7e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Cell-cycle control medial ring component DUF2340 PF10209.4 EGD92878.1 - 0.035 14.2 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) Pyridox_ox_2 PF12900.2 EGD92878.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Nol1_Nop2_Fmu PF01189.12 EGD92879.1 - 8e-96 320.7 0.0 1.2e-95 320.1 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EGD92879.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase UAA PF08449.6 EGD92880.1 - 7.8e-12 44.7 21.3 1e-11 44.3 14.8 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGD92880.1 - 4.3e-11 42.6 5.8 4.3e-11 42.6 4.0 2.9 1 1 2 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EGD92880.1 - 0.0032 17.4 5.1 0.0032 17.4 3.5 2.4 2 0 0 2 2 2 1 EamA-like transporter family DUF2431 PF10354.4 EGD92881.1 - 1.2e-30 106.7 0.0 3.1e-29 102.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) Nucleoplasmin PF03066.10 EGD92881.1 - 2.1 7.8 9.3 1.3 8.5 0.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin CLTH PF10607.4 EGD92882.1 - 2.1e-34 118.2 0.2 4.6e-34 117.2 0.1 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain INCA1 PF15142.1 EGD92882.1 - 0.038 13.7 0.1 0.092 12.5 0.1 1.6 2 0 0 2 2 2 0 INCA1 DKCLD PF08068.7 EGD92883.1 - 3.7e-30 103.6 0.1 3.1e-29 100.6 0.1 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EGD92883.1 - 7.5e-24 84.5 0.2 6.6e-21 75.0 0.1 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EGD92883.1 - 1.1e-20 73.1 1.2 2.1e-20 72.1 0.9 1.5 1 0 0 1 1 1 1 PUA domain CAF-1_p150 PF11600.3 EGD92883.1 - 0.0047 16.3 28.5 0.007 15.7 19.8 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4407 PF14362.1 EGD92883.1 - 0.42 9.5 11.4 0.68 8.8 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Metaviral_G PF09595.5 EGD92883.1 - 1.4 8.5 8.9 2.2 7.8 6.2 1.2 1 0 0 1 1 1 0 Metaviral_G glycoprotein MRP-S26 PF14943.1 EGD92883.1 - 1.8 8.0 19.7 3.7 7.0 13.6 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF4603 PF15376.1 EGD92883.1 - 4 4.5 17.1 5.5 4.0 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) RNase_H2-Ydr279 PF09468.5 EGD92883.1 - 7.7 5.6 19.1 12 4.9 13.2 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DER1 PF04511.10 EGD92884.1 - 7.6e-29 100.6 1.3 8.9e-29 100.4 0.9 1.0 1 0 0 1 1 1 1 Der1-like family Abhydrolase_3 PF07859.8 EGD92885.1 - 2.9e-44 151.1 0.0 5.5e-42 143.7 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EGD92885.1 - 6.3e-05 21.8 0.3 0.00047 18.9 0.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.4 EGD92885.1 - 0.13 11.5 0.1 2 7.6 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase MaoC_dehydratas PF01575.14 EGD92886.1 - 0.0037 16.6 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain PDT PF00800.13 EGD92887.1 - 9.2e-61 204.5 0.0 1.2e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EGD92887.1 - 2.5e-05 23.6 0.0 8.3e-05 21.9 0.0 1.9 1 1 0 1 1 1 1 ACT domain Glyco_hydro_67N PF03648.9 EGD92887.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus eRF1_2 PF03464.10 EGD92888.1 - 4.8e-46 156.3 0.1 8.5e-46 155.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EGD92888.1 - 3.7e-39 133.4 0.2 9.4e-39 132.1 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EGD92888.1 - 3.6e-21 75.1 0.0 1.9e-20 72.7 0.0 2.0 1 1 0 1 1 1 1 eRF1 domain 1 DUF3321 PF11968.3 EGD92890.1 - 6.5e-87 290.7 0.0 7.8e-87 290.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EGD92890.1 - 0.0073 16.0 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain INTS2 PF14750.1 EGD92890.1 - 0.12 9.9 0.0 0.15 9.5 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 Ribosomal_L23eN PF03939.8 EGD92891.1 - 6.1e-22 77.4 11.2 1.3e-21 76.3 7.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EGD92891.1 - 1.1e-13 50.9 0.8 1.1e-13 50.9 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein L23 Fork_head PF00250.13 EGD92892.1 - 1.8e-34 117.6 0.1 3.2e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Fork head domain G10 PF01125.12 EGD92893.1 - 7e-66 220.2 4.2 7.8e-66 220.0 2.9 1.0 1 0 0 1 1 1 1 G10 protein zf-Tim10_DDP PF02953.10 EGD92894.1 - 9.4e-19 66.4 2.6 1.2e-18 66.1 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FBA_2 PF07735.12 EGD92894.1 - 0.12 12.2 0.5 0.2 11.5 0.4 1.3 1 0 0 1 1 1 0 F-box associated AA_kinase PF00696.23 EGD92895.1 - 6.2e-42 143.8 0.1 1.1e-41 143.0 0.1 1.4 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.1 EGD92895.1 - 2.9e-14 52.3 1.5 1e-11 44.1 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EGD92895.1 - 1.2e-13 50.2 0.4 1.2e-10 40.5 0.1 2.8 2 0 0 2 2 2 2 ACT domain ITI_HC_C PF06668.7 EGD92896.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus Peptidase_C78 PF07910.8 EGD92897.1 - 5.9e-67 224.9 0.0 7.7e-67 224.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 EGD92897.1 - 0.00041 20.4 3.4 0.031 14.4 0.7 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EGD92897.1 - 0.072 13.4 2.0 5.5 7.5 0.7 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EGD92897.1 - 0.17 12.1 0.5 0.41 10.9 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain AAA_18 PF13238.1 EGD92898.1 - 1.1e-26 93.6 0.3 1.8e-26 92.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGD92898.1 - 9.5e-14 52.2 0.6 2.1e-13 51.1 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EGD92898.1 - 0.00025 21.2 0.0 0.00047 20.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGD92898.1 - 0.00055 19.9 0.5 0.00084 19.3 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGD92898.1 - 0.0011 18.9 0.0 0.0027 17.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGD92898.1 - 0.0013 18.5 0.0 0.01 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGD92898.1 - 0.0018 17.5 0.0 0.0051 16.0 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 EGD92898.1 - 0.0027 17.8 0.0 0.0052 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD92898.1 - 0.0035 17.3 0.1 0.007 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.10 EGD92898.1 - 0.0051 16.5 0.1 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 NTPase ADK PF00406.17 EGD92898.1 - 0.0057 16.5 0.1 0.021 14.7 0.0 1.9 2 1 0 2 2 2 1 Adenylate kinase Cytidylate_kin2 PF13189.1 EGD92898.1 - 0.026 14.4 0.2 0.045 13.6 0.1 1.7 1 1 0 1 1 1 0 Cytidylate kinase-like family RNA_helicase PF00910.17 EGD92898.1 - 0.031 14.4 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EGD92898.1 - 0.038 13.4 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EGD92898.1 - 0.048 13.0 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 EGD92898.1 - 0.086 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EGD92898.1 - 0.091 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ham1p_like PF01725.11 EGD92899.1 - 3.4e-51 173.2 0.0 3.9e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Myosin_head PF00063.16 EGD92900.1 - 4.9e-246 818.0 2.6 7.9e-246 817.4 1.8 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EGD92900.1 - 1e-34 118.5 3.4 2.9e-34 117.0 2.3 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EGD92900.1 - 2.3e-12 45.3 31.5 6.1e-05 22.3 0.4 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif GAS PF13851.1 EGD92900.1 - 0.00064 18.9 12.3 0.00064 18.9 8.5 2.9 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding AAA_22 PF13401.1 EGD92900.1 - 0.0022 18.1 3.0 0.0033 17.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain Fez1 PF06818.10 EGD92900.1 - 0.0045 17.0 16.0 0.0045 17.0 11.1 1.9 2 0 0 2 2 2 1 Fez1 T2SE PF00437.15 EGD92900.1 - 0.0063 15.4 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Myosin_N PF02736.14 EGD92900.1 - 0.012 15.2 2.9 0.029 14.0 2.0 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 EGD92900.1 - 0.021 14.5 0.0 0.061 13.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 EGD92900.1 - 0.048 12.8 0.0 0.14 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EGD92900.1 - 0.053 12.9 1.8 0.13 11.6 0.0 2.5 3 1 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 EGD92900.1 - 0.072 13.2 0.0 0.3 11.2 0.0 2.1 2 0 0 2 2 1 0 RNA helicase FlaC_arch PF05377.6 EGD92900.1 - 0.093 12.6 6.2 0.62 10.0 0.1 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) AAA_16 PF13191.1 EGD92900.1 - 0.12 12.3 0.0 0.12 12.3 0.0 2.9 2 1 0 2 2 1 0 AAA ATPase domain Reo_sigmaC PF04582.7 EGD92900.1 - 0.19 10.8 3.0 0.4 9.8 2.1 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 EGD92900.1 - 0.25 10.9 28.3 0.49 9.9 5.5 2.6 1 1 1 2 2 2 0 IncA protein Baculo_PEP_C PF04513.7 EGD92900.1 - 0.61 9.9 10.3 0.23 11.2 3.4 3.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus WEMBL PF05701.6 EGD92900.1 - 1.4 7.3 24.1 7.1 4.9 16.8 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DegQ PF08181.6 EGD92900.1 - 2.2 8.0 11.6 0.029 14.1 0.8 3.1 3 0 0 3 3 3 0 DegQ (SacQ) family TMF_DNA_bd PF12329.3 EGD92900.1 - 9.3 6.1 29.9 1.9 8.3 7.8 4.0 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding NAP PF00956.13 EGD92901.1 - 1.1e-85 286.6 7.5 1.1e-85 286.6 5.2 2.1 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.8 EGD92901.1 - 0.26 11.1 27.1 0.079 12.8 9.7 2.3 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 EGD92901.1 - 3.7 6.1 38.5 0.67 8.6 19.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) P5-ATPase PF12409.3 EGD92902.1 - 6e-39 132.5 0.0 1.2e-38 131.5 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EGD92902.1 - 1.3e-33 116.7 0.0 2.5e-33 115.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGD92902.1 - 2.7e-28 98.5 0.0 5.7e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGD92902.1 - 1.5e-19 71.2 0.0 9.4e-19 68.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD92902.1 - 0.00038 19.8 0.0 0.00096 18.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGD92902.1 - 0.0008 19.0 0.0 0.86 9.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD92902.1 - 0.0031 17.4 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit G_glu_transpept PF01019.16 EGD92903.1 - 8.5e-120 400.6 0.0 1.1e-119 400.2 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Peptidase_S64 PF08192.6 EGD92904.1 - 7.7e-07 27.8 0.6 1.1e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 Peptidase family S64 Peptidase_S7 PF00949.16 EGD92904.1 - 0.00021 20.7 0.0 0.0021 17.4 0.0 2.3 2 0 0 2 2 2 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S32 PF05579.8 EGD92904.1 - 0.0021 17.1 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Trypsin_2 PF13365.1 EGD92904.1 - 0.018 15.0 0.0 0.079 12.9 0.0 2.1 1 1 0 1 1 1 0 Trypsin-like peptidase domain ANAPC15 PF15243.1 EGD92904.1 - 0.043 13.8 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF31 PF01732.11 EGD92904.1 - 0.059 12.6 0.3 0.22 10.8 0.1 1.8 2 0 0 2 2 2 0 Putative peptidase (DUF31) Pkinase PF00069.20 EGD92905.1 - 8e-67 225.1 0.0 9.6e-67 224.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92905.1 - 3.1e-31 108.4 0.0 4.1e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD92905.1 - 0.014 14.3 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF605 PF04652.11 EGD92905.1 - 7.9 5.7 6.0 11 5.3 4.2 1.1 1 0 0 1 1 1 0 Vta1 like Transpep_BrtH PF14399.1 EGD92906.1 - 0.0051 16.1 1.1 0.0078 15.5 0.4 1.4 1 1 1 2 2 2 1 NlpC/p60-like transpeptidase IncA PF04156.9 EGD92906.1 - 0.032 13.8 7.8 0.039 13.5 5.4 1.1 1 0 0 1 1 1 0 IncA protein DUF1489 PF07370.6 EGD92906.1 - 0.038 13.5 1.2 0.056 12.9 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1489) BBP1_C PF15272.1 EGD92906.1 - 0.048 13.2 4.9 0.058 12.9 3.4 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal OPA3 PF07047.7 EGD92906.1 - 0.15 11.8 0.3 0.15 11.8 0.2 2.0 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) ATP-synt_E PF05680.7 EGD92906.1 - 0.18 11.7 4.8 0.099 12.6 0.4 2.1 2 0 0 2 2 2 0 ATP synthase E chain IFT57 PF10498.4 EGD92906.1 - 0.23 10.1 7.1 0.27 9.9 4.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BRE1 PF08647.6 EGD92906.1 - 0.24 11.3 5.8 0.31 11.0 3.3 1.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.3 EGD92906.1 - 1.8 8.3 9.2 0.45 10.3 0.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SIMPL PF04402.9 EGD92906.1 - 6.6 6.5 8.3 5.2 6.8 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF541) Vpu PF00558.14 EGD92906.1 - 7.6 6.1 9.2 0.25 10.9 0.2 2.5 1 1 2 3 3 3 0 Vpu protein 2-Hacid_dh_C PF02826.14 EGD92907.1 - 2.2e-48 163.7 0.0 3.5e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD92907.1 - 8.2e-34 115.9 0.0 1.2e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGD92907.1 - 9.5e-05 22.2 0.8 0.00021 21.2 0.2 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EGD92907.1 - 0.00021 20.7 0.2 0.0006 19.2 0.0 1.8 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.16 EGD92907.1 - 0.0057 16.5 0.1 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EGD92907.1 - 0.014 14.8 0.1 0.034 13.5 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EGD92907.1 - 0.1 12.2 1.4 1.4 8.5 0.4 2.6 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA-synt_2b PF00587.20 EGD92908.1 - 7.7e-30 103.7 0.0 1.2e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGD92908.1 - 2.3e-19 69.4 4.8 2.3e-19 69.4 3.3 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 EGD92908.1 - 0.032 13.8 2.5 0.075 12.6 1.8 1.6 1 0 0 1 1 1 0 Mnd1 family DUF4337 PF14235.1 EGD92908.1 - 0.72 9.6 4.0 1.4 8.7 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ras PF00071.17 EGD92909.1 - 5e-47 159.3 0.2 5.7e-47 159.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD92909.1 - 7.3e-17 61.9 0.1 1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD92909.1 - 2.8e-07 29.9 0.0 3.1e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGD92909.1 - 2e-06 27.7 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD92909.1 - 2.5e-06 27.0 0.2 8.2e-05 22.1 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGD92909.1 - 0.0012 18.1 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EGD92909.1 - 0.079 12.2 0.1 0.37 10.0 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NolV PF06635.7 EGD92910.1 - 0.097 11.8 2.6 5.6 6.0 0.9 2.1 2 0 0 2 2 2 0 Nodulation protein NolV WAPL PF07814.8 EGD92913.1 - 5.5e-30 104.3 2.8 8.4e-30 103.7 1.9 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.1 EGD92914.1 - 3.4e-77 258.3 0.0 4.4e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EGD92914.1 - 0.00076 19.2 0.0 0.0013 18.4 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EGD92914.1 - 0.15 11.7 0.5 0.27 10.9 0.4 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 EGD92915.1 - 2.1e-27 94.6 0.6 3.1e-27 94.0 0.4 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.1 EGD92915.1 - 0.19 11.6 0.5 0.19 11.6 0.3 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger GTP_CH_N PF12471.3 EGD92916.1 - 5.7e-92 306.7 0.0 8e-92 306.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EGD92916.1 - 3.1e-17 62.3 0.0 5.1e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Ribosomal_S3Ae PF01015.13 EGD92917.1 - 8.5e-77 256.8 7.0 1e-76 256.6 4.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SCO1-SenC PF02630.9 EGD92917.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 SCO1/SenC Abhydrolase_6 PF12697.2 EGD92918.1 - 7.2e-32 111.1 0.0 9.2e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD92918.1 - 4.4e-18 65.6 0.0 5.9e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD92918.1 - 8.3e-17 61.2 0.0 1.8e-16 60.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGD92918.1 - 2.8e-09 36.8 0.0 3.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EGD92918.1 - 9.2e-05 22.7 0.0 0.00015 22.1 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 EGD92918.1 - 0.00025 20.8 0.0 0.00046 19.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EGD92918.1 - 0.00084 18.9 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EGD92918.1 - 0.00095 18.6 0.0 0.0022 17.4 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Ndr PF03096.9 EGD92918.1 - 0.0019 16.7 0.0 0.0029 16.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Chlorophyllase PF07224.6 EGD92918.1 - 0.0044 15.8 0.0 0.0076 15.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase DUF915 PF06028.6 EGD92918.1 - 0.015 14.4 0.0 0.66 9.0 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.2 EGD92918.1 - 0.089 11.6 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydro_lipase PF04083.11 EGD92918.1 - 0.11 11.8 0.1 7.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Fungal_trans_2 PF11951.3 EGD92919.1 - 7.1e-06 24.8 0.0 1.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EGD92920.1 - 6.7e-39 133.6 1.0 9.5e-39 133.1 0.7 1.2 1 0 0 1 1 1 1 RTA1 like protein Ribonuclease_3 PF00636.21 EGD92921.1 - 1.2e-14 54.6 0.4 1e-13 51.7 0.0 2.7 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGD92921.1 - 4.1e-12 46.1 0.0 9.6e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EGD92921.1 - 0.16 12.5 0.1 0.16 12.5 0.0 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif MRP-S33 PF08293.6 EGD92922.1 - 2.7e-32 110.5 0.1 3.6e-32 110.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF382 PF04037.8 EGD92923.1 - 6.6e-29 100.3 0.0 6.6e-29 100.3 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF382) ER_lumen_recept PF00810.13 EGD92925.1 - 4.3e-56 189.5 7.2 4.3e-56 189.5 5.0 1.8 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EGD92925.1 - 3 7.4 16.5 0.99 9.0 0.1 4.5 4 1 1 5 5 5 0 PQ loop repeat zf-H2C2 PF09337.5 EGD92926.1 - 0.017 14.5 0.4 0.04 13.3 0.3 1.7 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger XRCC4 PF06632.7 EGD92928.1 - 3.2e-09 36.1 17.7 1e-08 34.4 12.3 1.7 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.3 EGD92928.1 - 0.0076 16.1 3.0 0.0076 16.1 2.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3585) DUF1759 PF03564.10 EGD92928.1 - 0.054 13.3 1.0 0.089 12.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF4407 PF14362.1 EGD92928.1 - 0.12 11.3 14.1 0.19 10.6 9.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.6 EGD92928.1 - 0.51 10.2 2.7 0.77 9.6 0.3 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 EGD92928.1 - 0.85 9.4 10.9 0.25 11.1 3.3 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EGD92928.1 - 4.1 6.9 6.8 6.7 6.2 4.7 1.4 1 0 0 1 1 1 0 IncA protein Molybdopterin PF00384.17 EGD92929.1 - 1.7e-70 237.9 0.0 6.9e-68 229.3 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EGD92929.1 - 4.6e-19 67.3 0.1 1.3e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 EGD92929.1 - 1.2e-14 53.8 0.1 3.7e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 EGD92929.1 - 1.9e-14 53.5 0.0 4.5e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EGD92929.1 - 8.9e-05 22.1 1.9 0.00014 21.5 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_19 PF06902.6 EGD92929.1 - 0.079 12.7 1.6 1.1 9.1 1.1 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.22 EGD92929.1 - 0.11 12.1 1.1 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.2 EGD92929.1 - 0.36 10.7 3.3 0.46 10.4 0.9 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain TPT PF03151.11 EGD92930.1 - 4.1e-38 130.4 4.7 4.1e-38 130.4 3.3 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EGD92930.1 - 7.5e-07 28.3 19.6 6.9e-06 25.1 13.6 2.0 1 1 0 1 1 1 1 UAA transporter family PSII PF00421.14 EGD92930.1 - 0.00013 20.7 0.2 0.00021 20.0 0.1 1.3 1 0 0 1 1 1 1 Photosystem II protein EamA PF00892.15 EGD92930.1 - 0.29 11.1 37.1 0.13 12.3 8.1 3.2 3 2 0 3 3 3 0 EamA-like transporter family Peptidase_S9 PF00326.16 EGD92931.1 - 3.4e-09 36.2 1.0 5.9e-09 35.4 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGD92931.1 - 1e-06 28.5 0.2 2.8e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGD92931.1 - 0.001 18.5 0.2 0.0026 17.2 0.1 1.6 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 EGD92931.1 - 0.046 13.1 0.1 2.4 7.5 0.0 2.6 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase PUF PF00806.14 EGD92932.1 - 6.7e-35 116.6 1.2 7.4e-06 25.1 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.6 EGD92932.1 - 0.059 14.0 0.0 0.28 11.8 0.0 2.0 2 0 0 2 2 2 0 Regulator of ribonuclease activity B Ssl1 PF04056.9 EGD92934.1 - 1.6e-73 246.4 0.0 2.2e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EGD92934.1 - 4.3e-17 61.8 8.3 4.3e-17 61.8 5.7 2.5 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EGD92934.1 - 3e-09 37.2 0.0 4.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EGD92934.1 - 0.00075 18.8 3.7 0.00075 18.8 2.6 1.9 2 0 0 2 2 2 1 Transcription factor Tfb4 DZR PF12773.2 EGD92934.1 - 3.4 7.5 20.7 5.1 6.9 4.1 3.3 2 1 0 2 2 2 0 Double zinc ribbon FYVE PF01363.16 EGD92934.1 - 6.3 6.7 18.7 0.041 13.7 3.8 2.6 2 0 0 2 2 2 0 FYVE zinc finger Peptidase_M1 PF01433.15 EGD92935.1 - 5.2e-128 427.4 0.3 7.5e-128 426.9 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EGD92935.1 - 2.1e-81 273.6 0.0 3.2e-81 273.0 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGD92935.1 - 4.8e-22 78.3 2.0 9.2e-22 77.4 1.4 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Ras PF00071.17 EGD92936.1 - 9e-66 220.2 0.6 1.1e-65 220.0 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD92936.1 - 1.1e-21 77.4 0.0 1.8e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD92936.1 - 1.3e-16 60.3 0.1 1.5e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGD92936.1 - 1.7e-05 24.0 0.1 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGD92936.1 - 5.5e-05 22.6 0.2 0.00012 21.6 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGD92936.1 - 6.5e-05 22.8 0.0 9.5e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EGD92936.1 - 0.00026 21.1 0.1 0.1 12.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EGD92936.1 - 0.00073 18.8 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EGD92936.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.7 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 EGD92936.1 - 0.003 16.8 0.1 0.019 14.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EGD92936.1 - 0.0081 15.3 0.0 0.022 13.9 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGD92936.1 - 0.019 14.9 0.1 0.064 13.2 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EGD92936.1 - 0.027 14.3 0.1 0.082 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EGD92936.1 - 0.029 13.3 0.1 0.2 10.6 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 EGD92936.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EGD92936.1 - 0.053 13.8 0.1 0.12 12.6 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EGD92936.1 - 0.057 13.1 0.1 0.13 12.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EGD92936.1 - 0.084 12.3 0.1 0.93 8.9 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EIIBC-GUT_N PF03612.9 EGD92938.1 - 0.73 9.4 3.1 1.3 8.6 2.2 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Mito_carr PF00153.22 EGD92939.1 - 1.1e-55 185.3 2.2 7.1e-19 67.3 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EGD92939.1 - 0.0035 17.1 0.2 0.0087 15.8 0.1 1.7 1 0 0 1 1 1 1 UcrQ family TnpW PF14202.1 EGD92939.1 - 0.048 13.2 0.2 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 Transposon-encoded protein TnpW Arteri_Gl PF00951.13 EGD92939.1 - 0.087 12.4 0.3 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein HMD PF03201.11 EGD92939.1 - 0.11 12.4 0.0 9.8 6.1 0.0 3.1 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase ATP_synt_I PF03899.10 EGD92939.1 - 0.16 12.1 6.1 3.5 7.8 0.0 3.7 2 1 2 4 4 4 0 ATP synthase I chain WD40 PF00400.27 EGD92940.1 - 5.2e-11 41.9 14.2 0.00017 21.3 0.1 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat UPF0029 PF01205.14 EGD92941.1 - 1.8e-32 111.2 0.0 3.2e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EGD92941.1 - 3.4e-07 30.1 0.0 5.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain Glyco_hydro_61 PF03443.9 EGD92942.1 - 0.00041 20.2 0.0 0.00073 19.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Chitin_bind_3 PF03067.10 EGD92942.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Chitin binding domain Ribosomal_L4 PF00573.17 EGD92944.1 - 2.5e-40 137.9 0.2 3.4e-40 137.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EGD92944.1 - 5.6e-30 103.0 1.1 1e-29 102.1 0.3 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DSPc PF00782.15 EGD92945.1 - 5e-24 84.3 0.0 6e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD92945.1 - 0.00046 19.6 0.0 0.0023 17.2 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGD92945.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate BCS1_N PF08740.6 EGD92946.1 - 3.6e-36 124.5 1.2 6.3e-36 123.7 0.9 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGD92946.1 - 2.4e-17 63.3 0.0 2.9e-15 56.6 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGD92946.1 - 0.0013 19.5 0.0 0.0073 17.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGD92946.1 - 0.0092 15.0 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 EGD92946.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 EGD92946.1 - 0.015 14.6 0.0 0.047 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGD92946.1 - 0.042 13.5 0.0 0.23 11.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EGD92946.1 - 0.054 13.0 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGD92946.1 - 0.07 13.1 0.6 0.46 10.4 0.3 2.4 2 1 0 2 2 2 0 AAA ATPase domain NAAA-beta PF15508.1 EGD92947.1 - 2e-21 76.1 0.0 2.4e-20 72.6 0.0 2.3 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF3395 PF11875.3 EGD92948.1 - 7.4e-40 136.0 0.0 1.7e-39 134.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EGD92948.1 - 2.7e-15 55.8 0.2 6.3e-15 54.6 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain CcmD PF04995.9 EGD92948.1 - 6.2 6.6 6.9 16 5.3 4.8 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) CAP_N PF01213.14 EGD92949.1 - 0.4 9.9 6.8 0.64 9.2 4.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SKIP_SNW PF02731.10 EGD92950.1 - 2.7e-68 228.4 5.8 2.7e-68 228.4 4.0 2.5 3 0 0 3 3 3 1 SKIP/SNW domain Borrelia_P83 PF05262.6 EGD92950.1 - 2.3 6.3 14.4 4.7 5.3 10.0 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein WD40 PF00400.27 EGD92951.1 - 2.4e-47 157.1 39.5 3.4e-12 45.7 0.5 12.5 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 EGD92951.1 - 2.7e-29 101.2 0.0 4.2e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EGD92951.1 - 2.3e-07 30.6 1.1 0.0078 15.9 0.0 5.2 5 1 0 6 6 6 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGD92951.1 - 7.7e-07 27.6 4.7 0.11 10.6 0.0 4.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Pox_T4_N PF04491.7 EGD92951.1 - 0.022 14.5 0.6 0.079 12.8 0.1 2.0 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus IKI3 PF04762.7 EGD92951.1 - 0.082 10.7 0.1 7.2 4.2 0.0 2.9 2 1 0 3 3 3 0 IKI3 family Hemagglutinin PF00509.13 EGD92951.1 - 0.18 9.9 0.0 0.28 9.2 0.0 1.2 1 0 0 1 1 1 0 Haemagglutinin Septin PF00735.13 EGD92952.1 - 2.3e-114 381.1 0.3 3.6e-114 380.5 0.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EGD92952.1 - 1.7e-07 31.2 0.0 3.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD92952.1 - 6.3e-06 25.7 0.3 0.00012 21.5 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGD92952.1 - 1.7e-05 24.0 0.0 5e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EGD92952.1 - 0.0033 17.8 0.1 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EGD92952.1 - 0.0036 16.9 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 EGD92952.1 - 0.0049 15.9 0.0 0.0094 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.1 EGD92952.1 - 0.006 16.7 0.8 0.013 15.5 0.0 2.1 2 2 0 2 2 2 1 AAA domain IIGP PF05049.8 EGD92952.1 - 0.0068 15.2 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 EGD92952.1 - 0.013 14.7 0.1 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 EGD92952.1 - 0.016 14.6 1.5 0.018 14.5 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 EGD92952.1 - 0.029 13.2 0.4 0.07 12.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.17 EGD92952.1 - 0.037 13.4 0.2 0.1 12.0 0.2 1.8 1 1 0 1 1 1 0 Ras family Dynamin_N PF00350.18 EGD92952.1 - 0.039 13.7 5.4 1.2 8.9 0.0 3.1 2 1 1 3 3 3 0 Dynamin family NACHT PF05729.7 EGD92952.1 - 0.04 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EGD92952.1 - 0.049 13.9 0.1 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EGD92952.1 - 0.065 13.2 1.0 0.48 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain PduV-EutP PF10662.4 EGD92952.1 - 0.076 12.5 0.3 2.9 7.3 0.2 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 EGD92952.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 EGD92952.1 - 0.11 11.4 2.1 0.24 10.3 1.5 1.8 1 1 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.12 EGD92952.1 - 0.17 11.4 0.6 10 5.5 0.1 2.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 EGD92952.1 - 0.25 10.0 2.8 0.94 8.2 0.0 2.6 3 0 0 3 3 3 0 ArgK protein Myc-LZ PF02344.10 EGD92952.1 - 0.63 9.7 5.0 0.83 9.3 0.2 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain WD40 PF00400.27 EGD92953.1 - 6.8e-31 105.0 21.1 3e-08 33.2 0.3 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ PF01011.16 EGD92953.1 - 0.00049 19.5 0.6 0.45 10.1 0.0 3.7 5 0 0 5 5 5 2 PQQ enzyme repeat FLgD_tudor PF13861.1 EGD92953.1 - 0.06 13.3 1.5 20 5.2 0.0 3.3 4 0 0 4 4 4 0 FlgD Tudor-like domain VID27 PF08553.5 EGD92953.1 - 0.066 11.4 0.1 0.099 10.8 0.0 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein ACT_7 PF13840.1 EGD92954.1 - 2.9e-23 81.1 0.2 4e-15 55.0 0.0 2.4 2 0 0 2 2 2 2 ACT domain XRN_N PF03159.13 EGD92955.1 - 4.1e-104 347.1 0.0 6.1e-104 346.5 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus WD40 PF00400.27 EGD92956.1 - 3.9e-43 143.8 4.5 6e-09 35.4 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGD92956.1 - 2.3e-31 107.4 1.0 5.4e-31 106.3 0.7 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex GTP_cyclohydroI PF01227.17 EGD92957.1 - 5.9e-73 243.9 0.2 8.5e-73 243.4 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EGD92957.1 - 0.00066 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein DUF4243 PF14027.1 EGD92959.1 - 2.3e-103 346.1 0.3 2.7e-103 345.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Lactamase_B_5 PF14597.1 EGD92959.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Pkinase PF00069.20 EGD92960.1 - 3.1e-70 236.2 0.0 5.1e-70 235.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92960.1 - 1e-32 113.2 0.0 1.8e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD92960.1 - 7.7e-05 21.8 0.2 0.00017 20.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD92960.1 - 0.0011 17.9 0.5 0.0052 15.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like NUDIX PF00293.23 EGD92961.1 - 7.4e-16 58.0 0.0 1.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EGD92961.1 - 9.2e-16 57.9 0.0 6.7e-15 55.2 0.0 2.3 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EGD92961.1 - 0.0016 17.9 1.4 0.0026 17.2 0.9 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DUF3574 PF12098.3 EGD92962.1 - 0.094 12.3 0.1 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Dynamin_N PF00350.18 EGD92963.1 - 1.1e-18 67.6 0.0 2.7e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGD92963.1 - 1.1e-06 27.6 0.1 1.5e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region FeoB_N PF02421.13 EGD92963.1 - 2.6e-05 23.5 0.4 0.026 13.7 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EGD92963.1 - 0.0036 17.2 0.0 0.026 14.4 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 EGD92963.1 - 0.011 15.5 0.5 0.038 13.8 0.1 2.1 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_23 PF13476.1 EGD92963.1 - 0.028 14.7 1.2 1.5 9.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Rop PF01815.11 EGD92963.1 - 0.2 11.1 1.6 4.7 6.7 0.0 2.7 2 0 0 2 2 2 0 Rop protein Helicase_C_3 PF13625.1 EGD92964.1 - 5.6e-26 90.8 0.0 3.9e-25 88.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD92964.1 - 5.7e-13 49.1 0.0 1.2e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGD92964.1 - 8.2e-13 48.0 0.0 1.8e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGD92964.1 - 1.6e-10 40.2 0.1 2.7e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_34 PF13872.1 EGD92964.1 - 0.0083 14.9 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF3669 PF12417.3 EGD92967.1 - 0.00017 21.2 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 Zinc finger protein CTD_bind PF04818.8 EGD92968.1 - 0.00013 22.0 0.0 0.00041 20.5 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. EMP24_GP25L PF01105.19 EGD92969.1 - 1.3e-43 148.8 0.2 1.6e-43 148.5 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD USP7_ICP0_bdg PF12436.3 EGD92970.1 - 2.9e-86 288.7 0.0 3.6e-85 285.1 0.0 2.2 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EGD92970.1 - 1.2e-69 234.0 1.6 8.3e-69 231.2 0.8 2.3 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 EGD92970.1 - 1.1e-51 175.4 0.3 1.9e-51 174.7 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD92970.1 - 4.1e-31 108.5 0.0 7.1e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EGD92970.1 - 6.7e-11 42.4 0.4 1e-09 38.6 0.0 2.8 2 0 0 2 2 2 1 MATH domain Rad60-SLD PF11976.3 EGD92970.1 - 0.068 12.8 0.8 1.7 8.3 0.0 3.6 4 1 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like BCDHK_Adom3 PF10436.4 EGD92971.1 - 3.4e-45 153.5 0.0 7e-45 152.4 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGD92971.1 - 1.5e-10 40.8 0.0 1.5e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGD92971.1 - 0.0079 15.9 0.0 0.99 9.1 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 EGD92971.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pmp3 PF01679.12 EGD92972.1 - 7.5e-17 60.7 9.1 1e-16 60.3 6.3 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SPC22 PF04573.7 EGD92973.1 - 1.1e-33 115.9 0.4 1.8e-25 89.2 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Peptidase_C48 PF02902.14 EGD92974.1 - 4.5e-32 111.4 0.3 8.5e-31 107.2 0.2 2.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.13 EGD92975.1 - 2.5e-52 176.7 0.1 4e-52 176.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Aminotran_1_2 PF00155.16 EGD92977.1 - 2.4e-27 95.8 0.0 2.9e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 EGD92977.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III POT1 PF02765.12 EGD92978.1 - 7.3e-12 45.4 0.0 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 zf-C2H2 PF00096.21 EGD92979.1 - 5.5e-15 54.7 43.1 0.014 15.7 0.8 6.7 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD92979.1 - 3.9e-13 48.9 44.4 0.0047 17.1 1.0 6.9 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGD92979.1 - 2.2e-10 40.0 46.1 0.069 13.5 1.7 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger GCC2_GCC3 PF07699.8 EGD92979.1 - 3.4e-06 26.5 21.6 0.0014 18.1 3.5 3.8 2 1 2 4 4 4 4 GCC2 and GCC3 zf-TRAF PF02176.13 EGD92979.1 - 0.077 13.3 22.4 2.4 8.5 3.5 4.6 1 1 4 5 5 5 0 TRAF-type zinc finger zf-met PF12874.2 EGD92979.1 - 5.7 7.3 18.4 5.1 7.4 0.3 6.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type ARS2 PF04959.8 EGD92979.1 - 5.8 7.0 14.5 18 5.4 0.4 4.6 2 2 3 5 5 5 0 Arsenite-resistance protein 2 DUF2841 PF11001.3 EGD92980.1 - 4e-46 155.9 0.1 6.9e-46 155.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF1590 PF07629.6 EGD92983.1 - 0.027 14.0 0.1 0.053 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) EST1_DNA_bind PF10373.4 EGD92984.1 - 4.7e-06 26.0 0.3 8.8e-06 25.1 0.2 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain tRNA-synt_1g PF09334.6 EGD92986.1 - 0.022 13.4 0.1 0.028 13.0 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) DnaB PF00772.16 EGD92986.1 - 0.034 14.0 0.1 0.082 12.7 0.1 1.6 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain Spc7 PF08317.6 EGD92986.1 - 0.093 11.3 0.2 1.2 7.7 0.0 1.9 1 1 0 2 2 2 0 Spc7 kinetochore protein COP23 PF14218.1 EGD92987.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Circadian oscillating protein COP23 zf-RING_2 PF13639.1 EGD92989.1 - 6.2e-10 38.7 10.9 2.9e-08 33.4 6.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EGD92989.1 - 0.00034 20.6 8.9 0.00063 19.7 4.1 2.8 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGD92989.1 - 0.0045 16.9 12.0 0.054 13.5 6.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD92989.1 - 0.0049 16.5 10.9 2 8.1 6.9 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGD92989.1 - 0.0062 16.1 6.0 0.0062 16.1 4.1 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD92989.1 - 0.045 13.4 14.9 0.31 10.7 0.0 3.4 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EGD92989.1 - 0.21 11.3 8.1 0.093 12.4 3.4 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.3 EGD92989.1 - 0.46 10.4 15.2 0.52 10.2 8.3 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.6 EGD92989.1 - 0.49 10.4 10.2 1 9.4 7.1 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EGD92989.1 - 0.75 9.5 8.0 2.1 8.1 5.6 1.8 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EGD92989.1 - 1.1 8.9 5.8 5 6.9 4.0 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 EGD92989.1 - 2.4 8.0 9.6 2.9 7.7 4.4 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EGD92989.1 - 2.7 8.1 9.7 6.6 6.8 6.7 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EGD92989.1 - 7.3 6.2 13.4 68 3.1 5.9 3.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain APH PF01636.18 EGD92990.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EGD92991.1 - 4.7e-08 32.5 0.2 1e-07 31.3 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92991.1 - 1.8e-06 27.2 0.1 2.6e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_8 PF08022.7 EGD92992.1 - 5.4e-10 39.0 0.0 1.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGD92992.1 - 2.2e-08 34.2 28.9 2.1e-07 31.0 8.1 3.1 1 1 2 3 3 3 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EGD92992.1 - 7.9e-05 22.6 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF3723 PF12520.3 EGD92993.1 - 7.5e-160 532.7 0.0 7.5e-160 532.7 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3723) DUF3552 PF12072.3 EGD92993.1 - 0.00031 20.0 74.2 0.00064 18.9 22.8 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF3552) DUF390 PF04094.9 EGD92993.1 - 0.25 9.3 8.8 0.38 8.7 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) SPATA24 PF15175.1 EGD92994.1 - 0.0036 16.9 11.5 0.031 13.9 5.3 2.7 1 1 1 2 2 2 1 Spermatogenesis-associated protein 24 TCTP PF00838.12 EGD92994.1 - 0.093 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Translationally controlled tumour protein Baculo_LEF-11 PF06385.7 EGD92994.1 - 1.2 9.3 8.7 1.2 9.3 0.7 2.7 2 1 1 3 3 3 0 Baculovirus LEF-11 protein TMF_DNA_bd PF12329.3 EGD92994.1 - 1.9 8.3 7.8 2.7 7.8 0.5 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.7 EGD92994.1 - 2.2 8.2 5.8 3.4 7.7 0.2 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF4094 PF13334.1 EGD92994.1 - 2.3 8.6 5.6 0.66 10.3 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) YlqD PF11068.3 EGD92994.1 - 2.5 8.1 15.1 5.1 7.1 4.3 2.6 1 1 0 2 2 2 0 YlqD protein Pkinase PF00069.20 EGD92996.1 - 0.00014 21.1 0.0 0.04 13.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Lumazine_bd PF12870.2 EGD92999.1 - 0.016 15.2 0.9 0.022 14.8 0.6 1.1 1 0 0 1 1 1 0 Lumazine-binding domain Transposase_22 PF02994.9 EGD92999.1 - 0.069 11.6 0.0 0.069 11.6 0.0 1.1 1 0 0 1 1 1 0 L1 transposable element NFRKB_winged PF14465.1 EGD92999.1 - 0.11 12.3 0.3 0.44 10.4 0.0 1.8 1 1 1 2 2 2 0 NFRKB Winged Helix-like GshA PF08886.6 EGD92999.1 - 0.13 10.5 0.6 0.18 10.0 0.4 1.3 1 1 0 1 1 1 0 Glutamate-cysteine ligase DUF3435 PF11917.3 EGD93000.1 - 0.0025 16.6 0.0 0.003 16.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Porin_OmpG PF09381.5 EGD93000.1 - 0.04 13.0 0.0 0.049 12.7 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) Phage_integrase PF00589.17 EGD93001.1 - 0.017 14.7 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 Phage integrase family FMO-like PF00743.14 EGD93002.1 - 1e-36 126.2 0.0 1.4e-22 79.5 0.0 2.6 2 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGD93002.1 - 1.6e-10 41.4 0.0 6.3e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD93002.1 - 6.3e-07 28.6 0.0 3.1e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGD93002.1 - 0.00019 21.3 0.0 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HDA2-3 PF11496.3 EGD93003.1 - 2.3e-35 121.8 0.0 2e-34 118.7 0.0 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF745 PF05335.8 EGD93003.1 - 0.047 13.2 18.9 0.016 14.7 4.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Med9 PF07544.8 EGD93003.1 - 0.22 11.2 22.2 0.3 10.8 1.0 4.5 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Bcr-Abl_Oligo PF09036.5 EGD93003.1 - 0.34 10.8 4.6 0.39 10.6 0.1 3.3 1 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Reo_sigmaC PF04582.7 EGD93003.1 - 0.36 9.9 8.8 0.62 9.1 1.0 2.6 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EGD93003.1 - 2.3 6.7 29.4 3.5 6.1 16.2 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein MIP PF00230.15 EGD93004.1 - 8.5e-46 156.2 12.0 1e-45 155.9 8.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein Transglut_core PF01841.14 EGD93006.1 - 2.2e-11 43.9 0.2 5.7e-11 42.6 0.2 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EGD93006.1 - 1e-08 34.5 0.2 2.6e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EGD93006.1 - 3.5e-06 26.5 0.1 4.7e-05 22.8 0.1 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EGD93006.1 - 5e-06 25.7 0.0 5e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 SH3 domain Transglut_core2 PF13369.1 EGD93006.1 - 0.2 11.1 0.0 0.43 10.0 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily DHHA2 PF02833.9 EGD93007.1 - 2e-19 70.0 0.0 3.6e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EGD93007.1 - 2.5e-07 30.4 0.0 6.7e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 DHH family PDZ_1 PF12812.2 EGD93007.1 - 0.13 12.1 0.2 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 PDZ-like domain PLU-1 PF08429.6 EGD93008.1 - 2.4e-98 329.1 17.1 2.5e-97 325.7 10.3 2.2 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.17 EGD93008.1 - 4.8e-42 142.7 0.8 1.5e-41 141.1 0.2 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.16 EGD93008.1 - 3.9e-27 93.9 0.1 1.3e-26 92.3 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 EGD93008.1 - 1e-18 66.5 2.4 2.3e-18 65.3 1.7 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 EGD93008.1 - 3e-18 65.2 28.3 1.2e-09 37.6 5.0 3.6 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.11 EGD93008.1 - 2.8e-13 49.7 4.9 8e-13 48.2 3.4 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger PHD_2 PF13831.1 EGD93008.1 - 0.0011 18.2 1.8 0.0011 18.2 1.2 3.0 3 0 0 3 3 3 1 PHD-finger zf-PHD-like PF15446.1 EGD93008.1 - 0.044 13.0 13.4 0.028 13.7 1.1 2.8 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain DUF515 PF04415.7 EGD93008.1 - 0.57 8.3 3.2 1.4 7.0 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF515) C1_1 PF00130.17 EGD93008.1 - 3.4 7.4 23.8 0.27 11.0 2.4 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GIY-YIG PF01541.19 EGD93010.1 - 3.5e-11 43.3 0.0 5.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.4 EGD93010.1 - 0.053 13.9 0.0 0.15 12.4 0.0 1.9 1 1 1 2 2 2 0 T5orf172 domain Thymidylate_kin PF02223.12 EGD93011.1 - 1.9e-41 141.5 0.0 2.2e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EGD93011.1 - 0.00019 21.4 0.0 0.00023 21.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGD93011.1 - 0.0021 17.3 0.0 0.0047 16.1 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_35 PF14516.1 EGD93011.1 - 0.08 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EGD93011.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain TGT PF01702.13 EGD93012.1 - 3.5e-39 134.5 0.0 4.6e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MFS_1 PF07690.11 EGD93013.1 - 2.4e-32 112.0 28.6 2.4e-32 112.0 19.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MTHFR PF02219.12 EGD93014.1 - 6.9e-93 310.8 0.0 1.2e-92 310.0 0.0 1.4 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase FLILHELTA PF10306.4 EGD93015.1 - 1.8e-25 88.7 0.0 3.1e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EGD93015.1 - 0.0041 17.3 0.4 0.0053 17.0 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) NDK PF00334.14 EGD93016.1 - 3.7e-56 188.6 0.0 4.2e-56 188.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 EGD93017.1 - 1.8e-146 488.4 5.7 2.4e-146 488.0 3.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGD93017.1 - 3e-25 87.8 0.4 8.3e-25 86.4 0.1 1.9 2 0 0 2 2 2 1 Galactose mutarotase-like PQ-loop PF04193.9 EGD93018.1 - 4.1e-21 74.2 4.6 1.4e-13 50.1 0.2 2.7 2 0 0 2 2 2 2 PQ loop repeat NMT1 PF09084.6 EGD93020.1 - 0.0019 17.8 0.0 0.039 13.5 0.0 2.5 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.1 EGD93020.1 - 0.081 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family SBP_bac_3 PF00497.15 EGD93020.1 - 0.11 11.7 0.0 0.77 8.9 0.0 2.0 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 FAD_binding_3 PF01494.14 EGD93021.1 - 1.2e-63 215.3 0.0 1.9e-62 211.4 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGD93021.1 - 6.6e-17 61.6 0.0 6.1e-16 58.4 0.0 2.5 2 1 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Glyco_hydro_16 PF00722.16 EGD93022.1 - 1e-05 24.9 0.0 2.3e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Ribosomal_L1 PF00687.16 EGD93023.1 - 7.7e-36 123.4 0.0 1.2e-35 122.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.6 EGD93024.1 - 9.9e-30 103.1 1.2 1.9e-29 102.2 0.8 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EGD93024.1 - 8.8e-06 25.4 1.8 1.9e-05 24.3 0.2 2.3 1 1 1 2 2 2 1 Vps51/Vps67 DUF2450 PF10475.4 EGD93024.1 - 0.024 13.5 0.4 0.045 12.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 EGD93024.1 - 0.026 14.1 0.6 0.061 12.9 0.4 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Spc7 PF08317.6 EGD93024.1 - 0.033 12.8 2.1 0.055 12.1 1.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein COG5 PF10392.4 EGD93024.1 - 0.038 13.9 1.3 0.05 13.5 0.2 1.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Seryl_tRNA_N PF02403.17 EGD93024.1 - 0.053 13.5 1.9 1.5 8.8 0.1 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Dor1 PF04124.7 EGD93024.1 - 0.071 11.5 1.4 0.099 11.0 1.0 1.2 1 0 0 1 1 1 0 Dor1-like family ING PF12998.2 EGD93024.1 - 0.15 12.3 4.1 1.1 9.5 1.3 2.6 2 2 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Bul1_C PF04426.7 EGD93024.1 - 0.17 11.0 0.9 6.1 5.9 0.0 2.1 1 1 1 2 2 2 0 Bul1 C terminus Atg14 PF10186.4 EGD93024.1 - 0.19 10.6 2.2 0.31 9.9 1.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EGD93024.1 - 0.37 10.3 5.0 0.77 9.3 3.5 1.6 1 0 0 1 1 1 0 IncA protein TBPIP PF07106.8 EGD93024.1 - 0.39 10.2 7.5 3.1 7.2 0.5 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATP-synt_F6 PF05511.6 EGD93026.1 - 0.038 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 ParA PF10609.4 EGD93028.1 - 1.3e-34 117.8 0.0 2.7e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGD93028.1 - 7.8e-13 48.2 0.0 1.9e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGD93028.1 - 2.4e-05 24.3 0.1 5.3e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EGD93028.1 - 3.9e-05 22.8 0.0 0.00015 20.9 0.0 1.8 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EGD93028.1 - 0.00022 20.3 0.5 0.00051 19.1 0.3 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EGD93028.1 - 0.0011 18.4 0.3 0.0022 17.4 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.1 EGD93028.1 - 0.012 15.2 0.7 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain YhjQ PF06564.7 EGD93028.1 - 0.017 14.5 0.3 0.025 13.9 0.2 1.5 1 1 0 1 1 1 0 YhjQ protein OrfB_Zn_ribbon PF07282.6 EGD93028.1 - 0.027 14.1 0.3 0.064 12.9 0.2 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain ArgK PF03308.11 EGD93028.1 - 0.04 12.7 0.2 0.066 11.9 0.1 1.3 1 0 0 1 1 1 0 ArgK protein APS_kinase PF01583.15 EGD93028.1 - 0.089 12.4 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_10 PF12846.2 EGD93028.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain Zot PF05707.7 EGD93028.1 - 0.13 11.6 0.1 0.26 10.7 0.0 1.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) DUF258 PF03193.11 EGD93028.1 - 0.22 10.6 1.1 0.37 9.9 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SEP PF08059.8 EGD93029.1 - 5.4e-26 90.7 0.1 1e-25 89.8 0.1 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EGD93029.1 - 1.3e-14 54.0 0.0 2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EGD93029.1 - 2.4e-14 52.5 0.0 3.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain TOM13 PF08219.6 EGD93030.1 - 7.8e-29 99.2 0.0 1e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.15 EGD93031.1 - 8.3e-32 110.4 0.5 1.2e-31 109.8 0.0 1.5 2 0 0 2 2 2 1 60Kd inner membrane protein TAFII28 PF04719.9 EGD93032.1 - 3.1e-21 74.9 0.7 1.2e-20 73.0 0.0 2.2 3 0 0 3 3 3 1 hTAFII28-like protein conserved region SAM_decarbox PF01536.11 EGD93033.1 - 1e-86 290.6 0.0 7.4e-86 287.8 0.0 2.2 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase DUF1546 PF07571.8 EGD93035.1 - 8.2e-33 112.3 0.0 2.1e-32 111.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EGD93035.1 - 3.6e-25 87.6 0.0 2e-24 85.3 0.0 2.2 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EGD93035.1 - 0.00033 20.6 0.0 0.0013 18.8 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EGD93035.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Bromodomain associated TAF4 PF05236.9 EGD93035.1 - 0.052 12.8 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CBFD_NFYB_HMF PF00808.18 EGD93035.1 - 0.054 13.5 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CRAL_TRIO PF00650.15 EGD93036.1 - 3.8e-13 49.2 0.0 6e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGD93036.1 - 0.00021 21.3 0.2 0.00083 19.4 0.0 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain IPP-2 PF04979.9 EGD93037.1 - 6.5e-09 36.1 17.9 4.1e-06 27.0 1.5 2.7 1 1 2 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) Carb_anhydrase PF00194.16 EGD93037.1 - 0.027 13.4 0.1 0.041 12.8 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase PAPA-1 PF04795.7 EGD93037.1 - 0.16 12.6 0.1 0.16 12.6 0.1 2.3 2 0 0 2 2 2 0 PAPA-1-like conserved region CAF1A PF12253.3 EGD93039.1 - 3.4e-25 87.9 4.8 3.4e-25 87.9 3.3 3.9 3 1 0 3 3 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EGD93039.1 - 7e-12 45.1 72.4 7e-12 45.1 50.2 2.0 2 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 EGD93039.1 - 0.00021 19.9 45.6 0.00033 19.2 31.6 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 SprA-related PF12118.3 EGD93039.1 - 0.11 11.8 29.8 0.23 10.7 20.7 1.6 1 0 0 1 1 1 0 SprA-related family Mem_trans PF03547.13 EGD93039.1 - 0.15 10.2 3.2 0.21 9.8 2.2 1.2 1 0 0 1 1 1 0 Membrane transport protein SAPS PF04499.10 EGD93039.1 - 0.17 10.4 12.7 0.28 9.7 8.8 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Asp-B-Hydro_N PF05279.6 EGD93039.1 - 0.25 11.1 32.5 0.5 10.1 22.5 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Nop14 PF04147.7 EGD93039.1 - 0.26 9.1 38.2 0.64 7.8 20.7 2.1 2 0 0 2 2 2 0 Nop14-like family AvrE PF11725.3 EGD93039.1 - 0.79 6.6 19.6 1.2 6.0 13.6 1.4 1 0 0 1 1 1 0 Pathogenicity factor Raftlin PF15250.1 EGD93039.1 - 6.5 5.1 21.9 11 4.4 15.2 1.3 1 0 0 1 1 1 0 Raftlin IncA PF04156.9 EGD93039.1 - 9.1 5.8 18.3 17 4.9 12.7 1.4 1 0 0 1 1 1 0 IncA protein Methyltransf_23 PF13489.1 EGD93041.1 - 5.2e-15 55.5 0.0 1.1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD93041.1 - 6.3e-05 22.5 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EGD93041.1 - 0.0066 16.8 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD93041.1 - 0.038 14.4 0.0 0.068 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Med15 PF09606.5 EGD93042.1 - 0.00014 20.2 30.8 0.00015 20.1 21.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 EGD93042.1 - 0.22 9.7 37.0 0.35 9.0 25.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CoA_transf_3 PF02515.12 EGD93043.1 - 3.4e-50 169.9 0.0 4.5e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Macoilin PF09726.4 EGD93044.1 - 0.00048 18.5 30.9 0.00048 18.5 21.4 2.5 2 1 0 2 2 2 1 Transmembrane protein DUF2611 PF11022.3 EGD93044.1 - 0.071 13.1 1.8 2.4 8.3 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) Reo_sigmaC PF04582.7 EGD93044.1 - 2.3 7.3 24.8 1.1 8.3 1.8 3.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 EGD93044.1 - 4.8 6.5 74.0 0.11 11.9 15.4 5.0 1 1 1 2 2 2 0 Intermediate filament protein Pox_A_type_inc PF04508.7 EGD93044.1 - 6.8 6.7 15.2 29 4.7 0.0 6.0 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat adh_short_C2 PF13561.1 EGD93045.1 - 1.1e-29 103.8 0.0 1.3e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD93045.1 - 9.8e-25 87.3 1.1 1.4e-24 86.9 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD93045.1 - 1.9e-11 43.9 0.6 2.8e-11 43.3 0.4 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EGD93045.1 - 0.0043 15.8 0.2 0.0054 15.4 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CcmE PF03100.10 EGD93045.1 - 0.041 13.4 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 CcmE Trypsin_2 PF13365.1 EGD93046.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S64 PF08192.6 EGD93046.1 - 0.083 11.2 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 Glyco_hydro_18 PF00704.23 EGD93048.1 - 2.9e-10 40.1 0.0 3.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PhoD PF09423.5 EGD93049.1 - 3e-55 187.6 0.0 4.2e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase SRP54 PF00448.17 EGD93050.1 - 1.2e-74 250.0 1.9 2.3e-74 249.1 1.3 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EGD93050.1 - 2.1e-23 82.5 0.2 2.1e-23 82.5 0.1 4.6 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.14 EGD93050.1 - 1.1e-15 57.4 0.2 2.4e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EGD93050.1 - 5.9e-09 35.6 0.2 1.6e-08 34.2 0.2 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EGD93050.1 - 4e-07 30.0 0.1 9.6e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD93050.1 - 7e-05 22.0 0.1 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EGD93050.1 - 8.1e-05 23.4 0.0 0.0002 22.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EGD93050.1 - 0.00018 21.2 0.0 0.00056 19.6 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EGD93050.1 - 0.00051 19.6 0.7 0.021 14.3 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EGD93050.1 - 0.00057 19.3 0.4 0.002 17.5 0.3 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGD93050.1 - 0.0009 19.2 0.0 1.9 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain 6PF2K PF01591.13 EGD93050.1 - 0.0016 17.5 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase APS_kinase PF01583.15 EGD93050.1 - 0.0017 18.0 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ArgK PF03308.11 EGD93050.1 - 0.0022 16.8 2.5 0.0042 15.9 0.0 2.5 3 0 0 3 3 3 1 ArgK protein SRPRB PF09439.5 EGD93050.1 - 0.0035 16.5 2.2 1.5 7.9 1.2 3.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.12 EGD93050.1 - 0.0063 15.9 0.2 0.022 14.1 0.1 1.9 1 0 0 1 1 1 1 Thymidylate kinase AAA_22 PF13401.1 EGD93050.1 - 0.0097 16.0 0.0 0.032 14.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD93050.1 - 0.0099 15.8 0.2 0.038 13.9 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EGD93050.1 - 0.019 14.3 0.1 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 EGD93050.1 - 0.033 14.5 0.0 0.078 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EGD93050.1 - 0.035 13.3 0.0 0.089 12.0 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family VirE PF05272.6 EGD93050.1 - 0.039 13.4 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E DUF2075 PF09848.4 EGD93050.1 - 0.044 12.7 0.1 0.086 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EGD93050.1 - 0.086 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGD93050.1 - 0.11 12.8 1.0 0.26 11.5 0.1 2.2 2 1 0 2 2 2 0 ABC transporter Rrp15p PF07890.7 EGD93051.1 - 8e-36 122.9 7.4 8e-36 122.9 5.1 1.8 2 0 0 2 2 2 1 Rrp15p Astro_capsid PF03115.9 EGD93051.1 - 0.06 11.6 9.5 0.078 11.2 6.6 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Mem_trans PF03547.13 EGD93051.1 - 0.71 8.0 2.1 0.77 7.9 1.5 1.2 1 0 0 1 1 1 0 Membrane transport protein RRN3 PF05327.6 EGD93051.1 - 1.5 6.8 4.9 2.1 6.3 3.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Fer2 PF00111.22 EGD93052.1 - 3e-14 52.5 0.7 4.5e-14 51.9 0.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 EGD93053.1 - 1.2e-10 40.9 0.0 0.28 10.9 0.0 5.4 4 1 0 4 4 4 4 Mitochondrial carrier protein bZIP_1 PF00170.16 EGD93054.1 - 3.2e-08 33.4 14.1 6e-08 32.5 9.2 1.9 1 1 0 1 1 1 1 bZIP transcription factor Hap4_Hap_bind PF10297.4 EGD93054.1 - 4.1e-08 32.8 7.1 9.4e-08 31.6 4.9 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 PSI_PsaF PF02507.10 EGD93054.1 - 0.086 12.3 1.3 0.15 11.5 0.9 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Phage_GPO PF05929.6 EGD93054.1 - 0.28 10.3 3.5 0.48 9.6 2.4 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase bZIP_2 PF07716.10 EGD93054.1 - 0.4 10.5 18.2 3.8 7.4 12.6 2.4 1 1 0 1 1 1 0 Basic region leucine zipper IncA PF04156.9 EGD93054.1 - 0.41 10.2 5.5 0.71 9.4 3.8 1.4 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 EGD93054.1 - 0.44 10.9 6.0 1.5 9.2 4.1 2.0 1 1 0 1 1 1 0 SlyX bZIP_Maf PF03131.12 EGD93054.1 - 0.58 10.4 11.4 2 8.7 7.9 1.9 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4407 PF14362.1 EGD93054.1 - 1.5 7.6 5.2 2.6 6.9 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 EGD93054.1 - 1.7 6.3 3.5 2.3 5.9 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EGD93054.1 - 6.5 6.3 9.5 3.4 7.2 3.3 2.2 1 1 1 2 2 2 0 Septum formation initiator Methyltransf_24 PF13578.1 EGD93055.1 - 2.2e-14 54.1 0.0 3.2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EGD93055.1 - 8.5e-05 21.6 0.0 0.00046 19.2 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGD93055.1 - 0.0056 17.2 0.0 0.016 15.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF365 PF04033.7 EGD93055.1 - 0.031 14.2 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Ribosomal_L19 PF01245.15 EGD93056.1 - 9.1e-16 57.6 0.0 1.8e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 AMP-binding PF00501.23 EGD93058.1 - 1.5e-14 53.1 0.0 9.2e-08 30.8 0.0 2.3 2 1 0 2 2 2 2 AMP-binding enzyme NPCC PF08058.6 EGD93059.1 - 1.5e-29 102.7 0.3 1.2e-28 99.7 0.2 1.9 1 1 0 1 1 1 1 Nuclear pore complex component HTH_21 PF13276.1 EGD93059.1 - 0.04 13.9 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 HTH-like domain Glycogen_syn PF05693.8 EGD93060.1 - 0 1112.7 0.0 0 1112.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EGD93060.1 - 2.8e-06 26.8 0.0 0.0032 16.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGD93060.1 - 8.5e-06 26.0 0.0 2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 EGD93060.1 - 5e-05 22.9 0.0 8.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain polyprenyl_synt PF00348.12 EGD93061.1 - 1.9e-50 171.1 0.0 5.5e-40 136.8 0.0 2.1 1 1 1 2 2 2 2 Polyprenyl synthetase APC8 PF04049.8 EGD93062.1 - 7.9e-54 181.2 0.1 3.5e-53 179.1 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EGD93062.1 - 1.2e-24 84.7 9.7 0.00015 21.2 0.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 EGD93062.1 - 9.1e-21 72.0 23.5 0.066 13.1 2.0 9.2 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 EGD93062.1 - 2.5e-20 71.8 19.6 3.5e-07 29.7 0.1 6.8 7 1 1 8 8 8 5 TPR repeat TPR_16 PF13432.1 EGD93062.1 - 1.2e-17 63.9 22.1 5.1e-05 23.8 0.0 7.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGD93062.1 - 2.6e-14 51.8 12.1 0.0003 20.3 0.0 7.7 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGD93062.1 - 7.5e-14 50.9 17.3 0.0055 17.2 0.0 8.9 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGD93062.1 - 8.7e-12 45.2 12.7 0.0081 16.4 0.3 7.7 7 2 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD93062.1 - 4e-11 42.6 20.0 0.00094 19.0 0.2 7.1 5 1 3 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.1 EGD93062.1 - 1.5e-10 40.7 11.6 3.8e-05 23.4 0.2 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD93062.1 - 6.7e-10 38.9 12.2 0.26 11.4 0.1 6.1 6 1 2 8 8 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EGD93062.1 - 2.4e-06 27.2 11.0 0.49 10.7 0.0 7.0 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD93062.1 - 1e-05 24.9 8.3 4.1 7.4 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGD93062.1 - 1.2e-05 25.4 24.7 0.46 11.0 0.1 9.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGD93062.1 - 0.00054 19.1 2.7 0.00054 19.1 1.8 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat PPR_3 PF13812.1 EGD93062.1 - 0.45 10.9 2.4 25 5.4 0.1 4.4 4 1 1 5 5 5 0 Pentatricopeptide repeat domain TPR_10 PF13374.1 EGD93062.1 - 7.7 6.5 18.1 16 5.5 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat DNA_ligase_A_M PF01068.16 EGD93063.1 - 1.8e-21 76.4 0.0 2.8e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGD93063.1 - 6.5e-15 55.3 0.0 1.2e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DUF3449 PF11931.3 EGD93065.1 - 1.6e-72 243.1 0.2 1.6e-72 243.1 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-met PF12874.2 EGD93065.1 - 1.8e-09 37.4 3.4 9.9e-08 31.9 0.6 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.3 EGD93065.1 - 6.1e-09 35.2 0.1 1.3e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 EGD93065.1 - 1.2e-07 31.6 0.7 1.2e-07 31.6 0.5 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGD93065.1 - 0.00017 21.6 0.2 0.009 16.1 0.0 2.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 EGD93065.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-LYAR PF08790.6 EGD93065.1 - 0.13 11.9 0.1 0.39 10.4 0.1 1.8 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.21 EGD93065.1 - 0.33 11.3 4.6 1.8 9.0 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD93065.1 - 0.47 10.8 3.5 3.9 8.0 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DEAD PF00270.24 EGD93066.1 - 5.4e-40 136.6 0.3 1.2e-39 135.4 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD93066.1 - 2.6e-29 100.8 0.2 5.6e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EGD93066.1 - 0.0013 18.4 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGD93066.1 - 0.011 15.3 0.3 0.027 14.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EGD93066.1 - 0.024 14.4 0.1 0.051 13.4 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EGD93066.1 - 0.031 14.0 0.3 0.12 12.1 0.1 2.2 1 1 1 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 EGD93066.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.20 EGD93066.1 - 0.1 11.7 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_11 PF13086.1 EGD93066.1 - 0.1 12.1 0.2 0.14 11.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGD93066.1 - 0.17 11.9 0.9 0.89 9.7 0.7 2.1 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 EGD93067.1 - 9.8e-36 120.3 9.7 4.4e-07 29.5 0.0 7.1 7 1 0 7 7 7 6 WD domain, G-beta repeat CLTH PF10607.4 EGD93067.1 - 0.00012 21.7 0.1 0.00022 20.9 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PD40 PF07676.7 EGD93067.1 - 0.001 18.6 0.7 14 5.5 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EGD93067.1 - 0.0037 17.0 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGD93067.1 - 0.19 9.9 0.0 1.5 7.0 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain ATP-synt_ab PF00006.20 EGD93068.1 - 6.8e-115 381.9 0.0 1e-114 381.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGD93068.1 - 8.2e-18 64.9 0.4 1.4e-17 64.1 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGD93068.1 - 6e-14 52.0 3.5 1.4e-13 50.8 2.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Dynamin_M PF01031.15 EGD93069.1 - 8.4e-105 349.7 0.0 1.8e-104 348.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EGD93069.1 - 1.4e-56 190.8 0.2 2.7e-56 189.9 0.2 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EGD93069.1 - 8.5e-29 99.3 3.0 2.1e-28 98.0 2.1 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGD93069.1 - 8.3e-06 25.7 0.3 7.6e-05 22.6 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD93069.1 - 0.0042 17.5 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein COesterase PF00135.23 EGD93070.1 - 7.3e-85 285.6 0.1 5.9e-80 269.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD93070.1 - 5e-15 55.6 0.0 9.2e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD93070.1 - 2.7e-06 27.1 0.0 4.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD93070.1 - 0.00019 21.3 0.1 0.0003 20.7 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EGD93070.1 - 0.0032 16.8 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 EGD93070.1 - 0.017 14.6 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EGD93070.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein TrkH PF02386.11 EGD93071.1 - 1.3e-116 389.1 9.6 5.5e-114 380.4 3.3 2.1 2 0 0 2 2 2 2 Cation transport protein Nramp PF01566.13 EGD93072.1 - 0.058 12.1 0.2 0.058 12.1 0.1 1.5 2 0 0 2 2 2 0 Natural resistance-associated macrophage protein CCDC155 PF14662.1 EGD93074.1 - 0.0046 16.5 1.9 0.0046 16.5 1.3 1.5 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 TPD52 PF04201.10 EGD93074.1 - 0.025 14.2 0.0 0.15 11.7 0.0 2.2 2 2 0 2 2 2 0 Tumour protein D52 family Sterile PF03015.14 EGD93074.1 - 0.047 13.9 1.1 0.099 12.9 0.3 1.8 1 1 1 2 2 2 0 Male sterility protein V_ATPase_I PF01496.14 EGD93074.1 - 0.16 9.8 1.6 0.23 9.2 1.1 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 EGD93074.1 - 5.2 6.9 6.8 1.7 8.5 1.0 2.6 2 1 1 3 3 3 0 Basic region leucine zipper OmpH PF03938.9 EGD93075.1 - 0.059 13.2 2.1 0.072 13.0 1.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PH PF00169.24 EGD93077.1 - 0.018 15.2 0.2 0.041 14.0 0.1 1.6 1 0 0 1 1 1 0 PH domain DUF4611 PF15387.1 EGD93077.1 - 1 9.5 7.4 2.5 8.2 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) F-box-like PF12937.2 EGD93078.1 - 3.1e-08 33.1 0.0 6.8e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGD93078.1 - 1.2e-05 24.7 1.1 0.44 10.2 0.1 5.0 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.28 EGD93078.1 - 0.038 13.6 0.2 4.2 7.1 0.0 3.3 3 0 0 3 3 3 0 F-box domain DUF1688 PF07958.6 EGD93079.1 - 1.3e-181 603.6 0.0 1.6e-181 603.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) TPR_11 PF13414.1 EGD93081.1 - 2.9e-11 42.8 0.1 2.9e-09 36.4 0.0 3.2 3 0 0 3 3 3 1 TPR repeat UBA PF00627.26 EGD93081.1 - 8.4e-07 28.6 0.0 3.4e-06 26.7 0.0 2.2 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.12 EGD93081.1 - 3.7e-06 26.4 0.6 0.38 10.7 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGD93081.1 - 0.0025 17.3 0.0 3.4 7.4 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGD93081.1 - 0.0038 17.1 0.0 0.19 11.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.26 EGD93081.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain Ank_5 PF13857.1 EGD93082.1 - 5.4e-21 74.1 0.6 3.5e-12 46.1 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGD93082.1 - 5e-17 62.0 0.4 6.7e-16 58.4 0.2 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGD93082.1 - 5.8e-15 54.2 1.5 5.4e-05 22.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EGD93082.1 - 1.7e-13 50.6 0.1 4.2e-08 33.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD93082.1 - 2e-11 42.9 0.3 0.016 15.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.16 EGD93082.1 - 0.022 14.6 6.3 0.048 13.6 4.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor AMP-binding PF00501.23 EGD93083.1 - 8.3e-81 271.5 0.0 1.1e-80 271.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGD93083.1 - 9.3e-25 87.0 0.0 1.4e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EGD93083.1 - 1.2e-09 38.2 0.0 3.9e-08 33.4 0.0 2.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site DegT_DnrJ_EryC1 PF01041.12 EGD93084.1 - 8.9e-67 225.6 0.0 1.2e-66 225.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GFO_IDH_MocA PF01408.17 EGD93084.1 - 1.6e-20 73.7 0.0 4.4e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EGD93084.1 - 0.00025 21.3 0.0 0.00055 20.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Beta_elim_lyase PF01212.16 EGD93084.1 - 0.00054 19.2 0.0 0.00098 18.3 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGD93084.1 - 0.0012 17.6 0.0 0.0025 16.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGD93084.1 - 0.0039 15.5 0.0 0.006 14.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme 5_nucleotid_C PF02872.13 EGD93086.1 - 1.1e-33 116.4 0.0 2.1e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EGD93086.1 - 0.00036 19.9 0.0 0.17 11.2 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase PGA_cap PF09587.5 EGD93086.1 - 0.00054 19.3 0.0 0.0069 15.7 0.0 2.4 2 1 0 2 2 2 1 Bacterial capsule synthesis protein PGA_cap tRNA-synt_1e PF01406.14 EGD93087.1 - 3.2e-114 381.1 0.0 4.8e-114 380.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EGD93087.1 - 1.4e-05 23.9 0.6 0.1 11.2 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EGD93087.1 - 0.002 18.3 0.1 0.0064 16.7 0.0 1.9 1 0 0 1 1 1 1 DALR domain GCD14 PF08704.5 EGD93088.1 - 1.9e-62 210.9 0.0 1.8e-61 207.7 0.0 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EGD93088.1 - 0.00016 21.6 0.0 0.00039 20.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD93088.1 - 0.0079 16.7 0.0 0.018 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PIH1 PF08190.7 EGD93088.1 - 0.025 14.0 5.3 0.051 13.0 3.7 1.4 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 RrnaAD PF00398.15 EGD93088.1 - 0.12 11.4 0.0 0.72 8.8 0.0 2.1 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase ABC_membrane PF00664.18 EGD93089.1 - 3.1e-70 236.7 40.2 2.5e-37 128.7 10.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD93089.1 - 3.4e-69 231.4 0.0 5.5e-34 117.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGD93089.1 - 7.8e-12 44.8 7.8 0.0015 17.8 0.1 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD93089.1 - 4.3e-10 40.0 0.4 0.054 13.4 0.1 4.3 2 2 1 4 4 4 3 AAA domain AAA_29 PF13555.1 EGD93089.1 - 1.5e-08 33.9 0.9 0.0048 16.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGD93089.1 - 8e-08 32.4 0.7 0.019 14.9 0.2 2.9 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EGD93089.1 - 5.7e-07 28.4 2.6 0.0026 16.3 0.0 2.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EGD93089.1 - 8e-07 29.9 0.0 0.061 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGD93089.1 - 9.2e-07 28.1 0.4 0.015 14.4 0.0 3.0 4 0 0 4 4 4 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGD93089.1 - 1.2e-06 28.9 0.1 0.02 15.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGD93089.1 - 1.2e-05 25.1 1.5 0.059 13.2 0.1 3.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DEAD PF00270.24 EGD93089.1 - 7e-05 22.3 0.0 0.064 12.7 0.0 3.3 4 1 0 4 4 4 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGD93089.1 - 9.9e-05 22.4 1.2 0.22 11.6 0.0 4.0 2 2 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EGD93089.1 - 0.00019 20.9 1.5 2.4 7.5 0.0 4.0 4 0 0 4 4 4 2 AAA-like domain MMR_HSR1 PF01926.18 EGD93089.1 - 0.00056 19.8 0.2 2.2 8.2 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.12 EGD93089.1 - 0.0011 18.7 0.2 1.3 8.7 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_18 PF13238.1 EGD93089.1 - 0.0012 19.2 0.0 1.6 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGD93089.1 - 0.0013 18.2 0.2 1.5 8.2 0.1 3.2 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EGD93089.1 - 0.0015 18.2 0.1 1.2 8.7 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EGD93089.1 - 0.0023 17.4 0.2 0.43 10.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 EGD93089.1 - 0.0032 17.3 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EGD93089.1 - 0.02 14.3 3.5 24 4.2 0.0 4.7 5 0 0 5 5 5 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGD93089.1 - 0.029 13.4 0.0 8.3 5.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.1 EGD93089.1 - 0.03 13.3 0.0 5.1 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 EGD93089.1 - 0.043 13.5 0.0 38 3.9 0.0 4.0 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 EGD93089.1 - 1.3 8.8 6.1 18 5.1 0.2 3.7 5 0 0 5 5 4 0 Dynamin family adh_short PF00106.20 EGD93090.1 - 1.8e-23 83.3 0.0 2.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD93090.1 - 2.5e-14 53.6 0.0 3.3e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD93090.1 - 2.2e-07 30.7 0.0 5.1e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 EGD93090.1 - 7e-07 28.6 0.0 9.1e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGD93090.1 - 0.0039 17.2 0.0 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding PQ-loop PF04193.9 EGD93091.1 - 3.4e-40 135.4 10.3 3.1e-20 71.4 0.7 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF566 PF04484.7 EGD93091.1 - 3 7.2 6.2 4.4 6.7 4.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF805 PF05656.9 EGD93091.1 - 4 7.2 7.2 1.5 8.6 0.2 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF805) SGS PF05002.10 EGD93092.1 - 1.1e-25 89.1 3.8 3.9e-25 87.4 2.6 2.0 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EGD93092.1 - 1.4e-19 70.3 0.0 3.2e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EGD93092.1 - 2.6e-07 30.1 0.1 1.4e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EGD93092.1 - 0.00021 20.7 1.0 0.0071 15.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGD93092.1 - 0.002 17.8 0.2 1.1 9.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Tom22 PF04281.8 EGD93092.1 - 0.049 13.1 1.5 0.13 11.8 1.0 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 TPR_16 PF13432.1 EGD93092.1 - 0.19 12.4 2.0 2.9 8.6 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat SLIDE PF09111.5 EGD93092.1 - 0.29 10.8 2.4 18 5.0 0.2 2.6 2 0 0 2 2 2 0 SLIDE Cwf_Cwc_15 PF04889.7 EGD93092.1 - 3.2 7.3 17.1 0.34 10.6 2.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2360 PF10152.4 EGD93092.1 - 7.6 6.8 10.1 0.36 11.1 2.4 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Prenyltrans PF00432.16 EGD93093.1 - 8e-31 105.2 4.1 3.5e-09 36.0 0.0 5.4 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EGD93093.1 - 1.8e-26 92.3 0.0 3.8e-11 42.9 0.0 5.9 5 1 1 6 6 6 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 EGD93093.1 - 1e-24 87.1 0.2 5.7e-14 52.4 0.1 4.8 3 1 2 5 5 5 3 Prenyltransferase-like Pec_lyase PF09492.5 EGD93093.1 - 2.5e-08 33.4 4.1 0.29 10.2 0.0 5.1 4 1 2 6 6 6 4 Pectic acid lyase A2M_comp PF07678.9 EGD93093.1 - 0.046 12.9 0.0 0.56 9.3 0.0 2.6 2 1 1 3 3 3 0 A-macroglobulin complement component Ank_2 PF12796.2 EGD93095.1 - 1.2e-34 118.4 5.8 4.6e-14 52.5 0.1 5.0 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD93095.1 - 3.7e-25 87.8 5.7 2.3e-08 34.2 0.0 5.8 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EGD93095.1 - 2.3e-23 80.7 10.8 2.6e-09 36.4 0.0 8.6 8 1 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EGD93095.1 - 9.5e-18 63.8 8.1 7.3e-10 38.7 0.3 6.2 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD93095.1 - 3.9e-16 57.5 17.4 4.4e-06 26.4 0.0 10.4 11 1 0 11 11 11 4 Ankyrin repeat F-box PF00646.28 EGD93095.1 - 0.00013 21.5 0.3 0.00028 20.4 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD93095.1 - 0.0014 18.2 0.2 0.0028 17.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like eIF-6 PF01912.13 EGD93096.1 - 2.5e-82 274.7 0.8 3.2e-82 274.4 0.6 1.1 1 0 0 1 1 1 1 eIF-6 family SRR1 PF07985.7 EGD93097.1 - 0.00038 20.3 0.0 0.002 18.0 0.0 2.2 3 0 0 3 3 3 1 SRR1 RSV_NS2 PF03113.9 EGD93097.1 - 0.052 13.5 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 Zn_clus PF00172.13 EGD93098.1 - 9.8e-05 22.1 8.2 0.00021 21.1 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.23 EGD93098.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family TauD PF02668.11 EGD93099.1 - 7.4e-36 124.1 0.0 9.3e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase_Tyr PF07714.12 EGD93100.1 - 2.7e-14 52.8 0.0 3.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGD93100.1 - 1e-10 41.2 0.0 1.8e-10 40.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGD93100.1 - 0.0098 15.6 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD93100.1 - 0.036 13.6 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PHO4 PF01384.15 EGD93101.1 - 7.9e-121 402.6 15.4 9.2e-121 402.4 10.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family Aminotran_1_2 PF00155.16 EGD93102.1 - 5.6e-43 147.2 0.0 6.8e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGD93102.1 - 1.6e-10 39.8 0.0 2.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EGD93102.1 - 7.2e-10 38.1 0.0 1.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGD93102.1 - 1.1e-07 31.3 0.0 1.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGD93102.1 - 0.004 16.2 0.0 0.0087 15.1 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3431 PF11913.3 EGD93103.1 - 2.2e-80 269.2 1.9 3.5e-80 268.6 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) XPC-binding PF09280.6 EGD93104.1 - 3.3e-23 80.8 15.3 3.3e-23 80.8 10.6 1.8 2 0 0 2 2 2 1 XPC-binding domain ubiquitin PF00240.18 EGD93104.1 - 6.7e-22 76.6 0.2 1.1e-21 76.0 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EGD93104.1 - 1.7e-17 62.6 0.6 1.4e-08 34.2 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EGD93104.1 - 1.2e-09 37.6 0.4 2.3e-09 36.8 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EGD93104.1 - 0.0063 16.0 0.0 1.9 8.1 0.0 2.5 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain MCM_N PF14551.1 EGD93104.1 - 0.0095 16.4 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 1 MCM N-terminal domain Rad60-SLD_2 PF13881.1 EGD93104.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rap1_C PF11626.3 EGD93104.1 - 0.044 13.6 0.0 3 7.7 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ubiquitin_2 PF14560.1 EGD93104.1 - 0.07 13.3 0.1 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.4 EGD93104.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain M_domain PF12938.2 EGD93104.1 - 0.87 9.3 19.7 0.034 13.9 6.4 2.3 2 0 0 2 2 2 0 M domain of GW182 Pheromone PF08015.6 EGD93104.1 - 2.5 8.9 10.4 4.5 8.1 3.0 2.8 2 0 0 2 2 2 0 Fungal mating-type pheromone Med3 PF11593.3 EGD93104.1 - 3.3 6.8 9.9 0.38 9.9 3.6 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Glyco_transf_22 PF03901.12 EGD93105.1 - 5.9e-59 200.1 21.9 9e-59 199.5 15.2 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Skp1 PF01466.14 EGD93106.1 - 1.2e-39 134.1 2.0 1.9e-39 133.5 1.4 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EGD93106.1 - 2e-23 82.2 0.1 4.4e-23 81.1 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain CM_2 PF01817.16 EGD93106.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Chorismate mutase type II Ribosomal_L39 PF00832.15 EGD93107.1 - 9.5e-22 76.1 9.0 1.4e-21 75.6 6.3 1.3 1 0 0 1 1 1 1 Ribosomal L39 protein ABC_membrane PF00664.18 EGD93108.1 - 1.2e-91 306.9 38.4 3.2e-47 161.2 8.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD93108.1 - 1.8e-68 229.0 0.0 3.7e-33 114.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGD93108.1 - 8.8e-15 54.5 0.0 0.0002 20.6 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD93108.1 - 3.6e-11 43.5 0.1 0.0037 17.2 0.0 4.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EGD93108.1 - 1.2e-08 34.3 0.6 0.0004 19.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EGD93108.1 - 5.2e-08 33.7 0.0 0.022 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGD93108.1 - 7.5e-08 32.5 2.1 0.0007 19.6 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EGD93108.1 - 2.9e-07 29.4 1.5 0.031 12.8 0.0 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EGD93108.1 - 1.4e-06 27.5 0.1 0.016 14.4 0.0 2.7 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGD93108.1 - 4e-06 27.0 1.3 0.21 11.6 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGD93108.1 - 4.6e-06 26.1 2.2 0.055 12.8 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 EGD93108.1 - 4.8e-05 23.0 0.6 2.6 7.5 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 EGD93108.1 - 0.00013 22.1 4.6 0.27 11.4 0.2 4.6 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EGD93108.1 - 0.00022 20.7 1.9 2.5 7.4 0.2 4.4 4 0 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 EGD93108.1 - 0.00023 21.0 0.0 0.81 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGD93108.1 - 0.00046 19.9 0.2 0.64 9.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGD93108.1 - 0.00064 20.0 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGD93108.1 - 0.0012 18.7 2.8 1.6 8.6 0.2 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 EGD93108.1 - 0.0018 17.7 0.1 1.2 8.5 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EGD93108.1 - 0.0028 17.3 0.7 2.3 8.0 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EGD93108.1 - 0.004 17.0 0.1 1.8 8.4 0.0 3.6 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.10 EGD93108.1 - 0.0051 15.5 0.2 0.22 10.1 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 EGD93108.1 - 0.0082 15.8 0.2 6.5 6.4 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EGD93108.1 - 0.01 16.1 4.8 2.4 8.4 0.0 3.7 3 1 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EGD93108.1 - 0.013 14.6 0.1 3.2 6.7 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.17 EGD93108.1 - 0.015 15.4 0.0 4.3 7.5 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EGD93108.1 - 0.016 15.1 0.3 4.3 7.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 EGD93108.1 - 0.042 13.3 0.0 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Katanin_con80 PF13925.1 EGD93108.1 - 0.14 11.8 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 con80 domain of Katanin MFS_1 PF07690.11 EGD93110.1 - 8.3e-61 205.6 57.4 3e-44 151.1 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGD93110.1 - 1.3e-07 30.3 20.8 1e-05 24.1 3.0 3.0 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 EGD93110.1 - 0.0024 16.0 3.2 0.0024 16.0 2.2 3.0 2 2 1 3 3 3 1 Transmembrane secretion effector Asp-Al_Ex PF06826.7 EGD93110.1 - 0.0086 15.5 8.2 0.0086 15.5 5.7 3.3 2 1 1 3 3 3 1 Predicted Permease Membrane Region MFS_1_like PF12832.2 EGD93110.1 - 0.014 15.2 3.8 1.5 8.6 0.0 3.6 3 0 0 3 3 3 0 MFS_1 like family tRNA-synt_2c PF01411.14 EGD93111.1 - 2.2e-09 36.1 0.1 2.9e-09 35.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EGD93111.1 - 3.9e-06 26.6 0.8 6.4e-06 25.9 0.5 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain WD40 PF00400.27 EGD93112.1 - 1.3e-23 81.9 10.9 4.1e-07 29.6 0.2 7.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Peptidase_S8 PF00082.17 EGD93112.1 - 1.4e-16 60.4 0.0 2.5e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Subtilase family NACHT PF05729.7 EGD93112.1 - 7.7e-07 28.9 0.7 2.1e-06 27.5 0.1 2.0 2 0 0 2 2 2 1 NACHT domain PD40 PF07676.7 EGD93112.1 - 1e-05 25.0 3.4 36 4.1 0.0 7.9 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat KAP_NTPase PF07693.9 EGD93112.1 - 5.4e-05 22.3 0.0 9.1e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.1 EGD93112.1 - 0.0036 17.2 0.0 0.0093 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Nbas_N PF15492.1 EGD93112.1 - 0.0072 15.4 0.5 8.4 5.3 0.0 4.1 4 1 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.6 EGD93112.1 - 0.03 13.2 0.0 0.6 8.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) AAA_22 PF13401.1 EGD93112.1 - 0.093 12.8 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Proteasome_A_N PF10584.4 EGD93112.1 - 0.14 11.5 12.7 3.6 6.9 0.0 6.0 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF839 PF05787.8 EGD93112.1 - 0.33 9.8 0.0 0.5 9.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) AFOR_N PF02730.10 EGD93113.1 - 0.0014 18.0 0.0 0.0019 17.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain Glyco_transf_54 PF04666.8 EGD93114.1 - 1.3e-11 43.7 0.0 1.2e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region MUG113 PF13455.1 EGD93115.1 - 2.5e-27 95.1 0.7 4.8e-27 94.2 0.5 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EGD93115.1 - 4e-18 65.6 0.2 9.6e-18 64.4 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Herpes_UL45 PF05473.7 EGD93116.1 - 0.33 10.3 1.8 0.56 9.5 1.2 1.5 1 0 0 1 1 1 0 UL45 protein Phage_GP20 PF06810.6 EGD93117.1 - 0.0011 18.4 19.0 0.0011 18.4 13.2 4.7 3 1 1 4 4 4 2 Phage minor structural protein GP20 Nup54 PF13874.1 EGD93117.1 - 0.65 9.6 19.6 0.041 13.5 7.9 2.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 SecY PF00344.15 EGD93118.1 - 3e-87 292.7 5.6 3.8e-87 292.4 3.9 1.0 1 0 0 1 1 1 1 SecY translocase ArgJ PF01960.13 EGD93119.1 - 2.3e-147 490.4 0.0 2.6e-147 490.2 0.0 1.0 1 0 0 1 1 1 1 ArgJ family ORC2 PF04084.9 EGD93120.1 - 4.2e-94 315.0 0.0 5.1e-94 314.7 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.14 EGD93120.1 - 3.1 7.7 9.4 9.7 6.2 6.5 1.9 1 0 0 1 1 1 0 AT hook motif FUN14 PF04930.10 EGD93121.1 - 7.2e-10 39.0 0.3 2.3e-09 37.4 0.2 1.8 1 1 0 1 1 1 1 FUN14 family DUF3487 PF11990.3 EGD93121.1 - 0.22 10.9 1.5 0.36 10.2 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3487) SOR_SNZ PF01680.12 EGD93122.1 - 9.1e-110 365.1 5.4 9.1e-110 365.1 3.7 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 EGD93122.1 - 2.2e-09 36.7 7.3 1.3e-07 30.9 0.0 2.7 3 1 1 4 4 4 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EGD93122.1 - 0.00058 19.2 0.4 0.01 15.1 0.0 2.7 3 0 0 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 EGD93122.1 - 0.0032 16.3 0.4 0.35 9.6 0.0 2.4 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) IGPS PF00218.16 EGD93122.1 - 0.0039 16.2 0.0 0.055 12.5 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 EGD93122.1 - 0.02 13.8 0.8 0.21 10.5 0.0 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.12 EGD93122.1 - 0.032 13.3 0.6 0.85 8.7 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI OMPdecase PF00215.19 EGD93122.1 - 0.032 13.6 0.1 0.36 10.1 0.0 2.2 1 1 2 3 3 3 0 Orotidine 5'-phosphate decarboxylase / HUMPS family NMO PF03060.10 EGD93122.1 - 0.17 10.9 4.8 0.17 11.0 0.1 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase Xpo1 PF08389.7 EGD93124.1 - 0.034 14.0 0.0 0.45 10.4 0.0 2.7 2 0 0 2 2 2 0 Exportin 1-like protein Peptidase_M24 PF00557.19 EGD93125.1 - 3.8e-39 134.4 0.0 5.7e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EGD93125.1 - 8.7e-24 84.5 0.0 7.1e-20 71.8 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Tubulin PF00091.20 EGD93127.1 - 1.6e-65 220.9 0.0 2.4e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGD93127.1 - 2e-47 160.3 0.2 3.6e-47 159.5 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGD93127.1 - 0.0022 17.4 0.0 0.0057 16.1 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 EGD93127.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) EF-hand_4 PF12763.2 EGD93128.1 - 6.7e-39 131.8 0.0 1.3e-15 56.9 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EGD93128.1 - 4.9e-12 45.8 0.1 4e-06 26.8 0.1 4.0 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EGD93128.1 - 1.7e-06 26.9 1.7 0.018 14.3 0.0 5.7 7 0 0 7 7 6 1 EF hand UBA PF00627.26 EGD93128.1 - 2.4e-06 27.2 0.1 4.6e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.1 EGD93128.1 - 6.5e-05 22.4 3.4 15 5.7 0.0 6.3 7 0 0 7 7 6 0 EF-hand domain EF-hand_8 PF13833.1 EGD93128.1 - 0.0016 17.9 0.5 0.02 14.4 0.0 3.1 3 0 0 3 3 2 1 EF-hand domain pair Fib_alpha PF08702.5 EGD93128.1 - 0.0042 17.2 8.7 0.0042 17.2 6.0 2.3 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family BicD PF09730.4 EGD93128.1 - 0.0053 15.1 25.1 0.011 14.1 17.4 1.4 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF812 PF05667.6 EGD93128.1 - 0.021 13.3 18.5 0.044 12.3 12.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.1 EGD93128.1 - 0.066 12.4 32.2 0.46 9.6 11.9 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EGD93128.1 - 0.17 11.7 32.1 0.032 14.1 8.5 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EGD93128.1 - 0.46 9.4 31.5 0.0071 15.4 13.6 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3584 PF12128.3 EGD93128.1 - 0.65 7.2 30.5 0.92 6.7 21.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 EGD93128.1 - 0.8 7.3 34.6 1.4 6.5 10.2 1.9 1 1 1 2 2 2 0 Myosin tail TPR_MLP1_2 PF07926.7 EGD93128.1 - 2.3 7.9 34.5 1.3 8.8 14.7 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fmp27_WPPW PF10359.4 EGD93128.1 - 2.5 6.4 20.0 0.1 10.9 2.2 2.7 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain IFT57 PF10498.4 EGD93128.1 - 4.6 5.8 21.0 8 5.1 14.5 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Reo_sigmaC PF04582.7 EGD93128.1 - 5.1 6.1 7.5 1.3 8.0 1.3 2.0 1 1 0 1 1 1 0 Reovirus sigma C capsid protein zf-C4H2 PF10146.4 EGD93128.1 - 6.6 6.6 15.0 11 5.9 8.1 3.0 1 1 0 1 1 1 0 Zinc finger-containing protein CALCOCO1 PF07888.6 EGD93128.1 - 7.3 4.7 21.7 11 4.1 15.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.16 EGD93128.1 - 9.2 5.6 29.8 1.3 8.4 12.0 2.1 1 1 1 2 2 2 0 Intermediate filament protein MARVEL PF01284.18 EGD93129.1 - 3.9e-18 65.6 21.0 5e-18 65.3 14.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Oleosin PF01277.12 EGD93129.1 - 0.95 9.0 4.6 3.4 7.2 3.2 2.1 1 1 0 1 1 1 0 Oleosin Sulfotransfer_3 PF13469.1 EGD93130.1 - 9e-08 33.1 0.5 1.6e-07 32.4 0.3 1.6 1 1 0 1 1 1 1 Sulfotransferase family AAA_17 PF13207.1 EGD93130.1 - 0.09 13.5 0.0 0.16 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Cys_Met_Meta_PP PF01053.15 EGD93131.1 - 1.4e-144 481.1 0.0 1.6e-144 480.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGD93131.1 - 1.1e-15 57.5 0.9 1.5e-15 57.1 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EGD93131.1 - 3.6e-09 36.0 0.1 5.9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGD93131.1 - 3.1e-07 29.4 0.1 5e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGD93131.1 - 1.8e-05 24.0 0.0 2.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EGD93131.1 - 0.029 12.8 0.0 0.045 12.2 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 EGD93131.1 - 0.06 12.0 0.0 0.094 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein AMP-binding PF00501.23 EGD93132.1 - 1.1e-77 261.2 0.0 1.3e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2012 PF09430.5 EGD93133.1 - 1.1e-24 86.5 0.0 1.6e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) LCCL PF03815.14 EGD93134.1 - 3.9e-20 71.6 0.2 6.2e-20 70.9 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Senescence_reg PF04520.8 EGD93134.1 - 0.027 14.9 0.0 0.048 14.1 0.0 1.3 1 0 0 1 1 1 0 Senescence regulator PBP1_TM PF14812.1 EGD93134.1 - 9.1 6.6 6.9 6 7.2 2.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3328 PF11807.3 EGD93135.1 - 0.038 13.6 3.0 1.5 8.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EGD93136.1 - 3.1e-47 161.0 0.5 3.8e-47 160.7 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ank_2 PF12796.2 EGD93137.1 - 2e-38 130.6 5.4 2.9e-25 88.3 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD93137.1 - 1.9e-29 101.4 3.0 4.2e-15 55.7 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EGD93137.1 - 2.1e-29 99.8 2.6 1.1e-09 37.6 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EGD93137.1 - 2.8e-23 81.3 4.1 8.9e-09 35.3 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD93137.1 - 1.3e-20 71.4 0.2 3.7e-08 32.8 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.16 EGD93137.1 - 0.0072 16.2 8.4 0.013 15.4 5.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor Sds3 PF08598.6 EGD93137.1 - 0.023 14.2 3.5 0.13 11.8 3.3 1.5 2 0 0 2 2 2 0 Sds3-like PTR2 PF00854.16 EGD93138.1 - 9.2e-38 129.9 15.4 7.2e-24 84.2 6.1 2.1 2 0 0 2 2 2 2 POT family TPD52 PF04201.10 EGD93138.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Tumour protein D52 family DUF2207 PF09972.4 EGD93138.1 - 0.18 10.3 0.6 0.31 9.5 0.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Methyltransf_32 PF13679.1 EGD93140.1 - 2.7e-19 69.2 1.2 6.7e-19 67.9 0.9 1.7 1 1 0 1 1 1 1 Methyltransferase domain Atg14 PF10186.4 EGD93140.1 - 0.14 11.1 0.1 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin-6_N PF09177.6 EGD93141.1 - 7.5e-23 80.7 1.3 3e-22 78.8 0.1 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EGD93141.1 - 8.8e-12 44.5 3.6 8.8e-12 44.5 2.5 2.7 3 0 0 3 3 3 1 SNARE domain CK2S PF15011.1 EGD93141.1 - 0.05 13.3 1.0 1.1 8.9 0.2 2.6 3 0 0 3 3 3 0 Casein Kinase 2 substrate PilJ PF13675.1 EGD93141.1 - 0.051 13.8 1.7 0.26 11.6 0.1 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Syntaxin_2 PF14523.1 EGD93141.1 - 0.06 13.3 0.5 0.37 10.8 0.0 2.4 2 1 1 3 3 3 0 Syntaxin-like protein Vps51 PF08700.6 EGD93141.1 - 0.067 13.0 4.2 8.2 6.3 0.0 3.3 3 0 0 3 3 3 0 Vps51/Vps67 Reo_sigmaC PF04582.7 EGD93141.1 - 0.097 11.8 0.5 0.81 8.8 0.0 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Med30 PF11315.3 EGD93141.1 - 0.11 12.5 1.9 12 6.0 0.1 3.0 3 0 0 3 3 3 0 Mediator complex subunit 30 Laminin_II PF06009.7 EGD93141.1 - 0.13 12.0 1.4 3.4 7.4 0.1 2.6 2 1 1 3 3 3 0 Laminin Domain II DUF883 PF05957.8 EGD93141.1 - 0.39 11.1 5.4 12 6.3 0.0 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TBPIP PF07106.8 EGD93141.1 - 0.53 9.8 0.0 0.53 9.8 0.0 2.7 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3618 PF12277.3 EGD93141.1 - 0.61 10.1 10.5 1.4 8.9 0.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) CENP-F_leu_zip PF10473.4 EGD93141.1 - 5.5 6.8 12.9 13 5.6 0.1 3.7 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NAP PF00956.13 EGD93142.1 - 2.4e-29 102.1 6.6 2.4e-29 102.1 4.5 1.9 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) NmrA PF05368.8 EGD93143.1 - 6.8e-64 215.3 0.0 8.3e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD93143.1 - 3.7e-06 27.0 0.0 5.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DUF1876 PF08962.6 EGD93143.1 - 0.04 13.6 0.2 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) Asparaginase PF00710.15 EGD93144.1 - 3.5e-106 354.6 0.0 4e-106 354.4 0.0 1.0 1 0 0 1 1 1 1 Asparaginase MTTB PF06253.6 EGD93144.1 - 0.013 13.2 0.3 0.019 12.7 0.2 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) 2-Hacid_dh_C PF02826.14 EGD93145.1 - 1.4e-46 157.9 0.1 2e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EGD93145.1 - 4.3e-06 26.6 0.1 6.3e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGD93145.1 - 0.00042 20.6 0.1 0.00084 19.7 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EGD93145.1 - 0.048 14.1 0.1 0.096 13.2 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EGD93145.1 - 0.059 13.7 0.3 0.13 12.6 0.2 1.7 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD93145.1 - 0.079 12.4 0.0 0.079 12.4 0.0 1.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DapB_N PF01113.15 EGD93145.1 - 0.14 12.0 0.1 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Peptidase_S8 PF00082.17 EGD93146.1 - 6.6e-29 100.9 1.0 7.3e-29 100.7 0.0 1.5 2 0 0 2 2 2 1 Subtilase family Kdo PF06293.9 EGD93147.1 - 0.007 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD93150.1 - 2e-09 37.5 0.0 7.4e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1996 PF09362.5 EGD93153.1 - 2.1e-78 263.2 0.0 3.3e-78 262.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AdoMet_MTase PF07757.8 EGD93153.1 - 0.013 15.5 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase adh_short_C2 PF13561.1 EGD93154.1 - 4.2e-34 118.3 0.0 5.4e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD93154.1 - 6.1e-30 104.3 0.0 7.4e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD93154.1 - 6.3e-06 25.9 0.3 1.6e-05 24.6 0.2 1.6 1 1 0 1 1 1 1 KR domain HI0933_like PF03486.9 EGD93154.1 - 0.036 12.5 0.3 0.044 12.2 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Epimerase PF01370.16 EGD93154.1 - 0.037 13.4 0.1 0.087 12.2 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGD93154.1 - 0.09 12.5 0.6 0.18 11.6 0.4 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AA_permease_2 PF13520.1 EGD93155.1 - 4.8e-41 140.6 51.7 5.8e-41 140.4 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD93155.1 - 1.5e-18 66.3 42.5 2.1e-18 65.9 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease ELO PF01151.13 EGD93158.1 - 5.1e-57 193.0 22.0 5.9e-56 189.5 15.2 1.9 1 1 0 1 1 1 1 GNS1/SUR4 family COX5A PF02284.11 EGD93159.1 - 8.8e-38 128.5 1.0 1.2e-37 128.1 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ABC_tran PF00005.22 EGD93160.1 - 3.3e-66 221.7 0.0 5.6e-32 110.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGD93160.1 - 8.1e-60 202.5 33.4 1e-35 123.5 8.3 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EGD93160.1 - 2.1e-16 59.8 2.5 1.8e-05 24.0 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EGD93160.1 - 5.9e-11 41.6 0.6 0.00078 18.1 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EGD93160.1 - 3.4e-10 39.3 0.1 0.00053 19.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EGD93160.1 - 8.8e-10 39.0 0.1 0.021 14.8 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EGD93160.1 - 1.3e-08 35.6 0.0 0.0012 19.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGD93160.1 - 2.3e-08 34.2 6.2 0.00014 21.9 0.2 3.4 2 1 1 3 3 3 2 AAA ATPase domain DUF87 PF01935.12 EGD93160.1 - 1.4e-07 31.5 0.4 0.00095 19.0 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_22 PF13401.1 EGD93160.1 - 1.5e-06 28.3 1.5 0.12 12.5 0.0 4.1 3 1 1 4 4 4 2 AAA domain DUF258 PF03193.11 EGD93160.1 - 9.2e-06 24.9 0.0 0.13 11.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EGD93160.1 - 1.9e-05 24.3 3.2 0.097 12.0 0.0 3.8 4 1 1 5 5 5 2 AAA-like domain AAA_18 PF13238.1 EGD93160.1 - 6.4e-05 23.2 0.1 0.11 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGD93160.1 - 7.2e-05 22.2 0.1 0.4 10.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EGD93160.1 - 0.00012 21.1 0.0 0.23 10.5 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.1 EGD93160.1 - 0.00014 21.5 1.0 0.38 10.2 0.0 4.0 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.13 EGD93160.1 - 0.00021 20.8 0.0 0.0073 15.8 0.0 2.7 3 0 0 3 3 2 1 FtsK/SpoIIIE family DUF3987 PF13148.1 EGD93160.1 - 0.00029 19.5 0.1 0.38 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA_23 PF13476.1 EGD93160.1 - 0.00039 20.7 0.1 0.59 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGD93160.1 - 0.00051 19.9 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGD93160.1 - 0.00082 19.2 2.8 0.36 10.7 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EGD93160.1 - 0.0024 17.5 0.2 2.4 7.8 0.0 3.2 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EGD93160.1 - 0.0045 16.7 0.1 5.4 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EGD93160.1 - 0.0052 16.2 1.3 0.41 10.0 0.0 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EGD93160.1 - 0.0062 16.2 2.5 3.5 7.4 0.0 3.9 3 0 0 3 3 3 1 Part of AAA domain TrwB_AAD_bind PF10412.4 EGD93160.1 - 0.0068 15.0 0.1 0.82 8.2 0.0 3.0 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.1 EGD93160.1 - 0.0095 15.9 0.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGD93160.1 - 0.05 13.5 0.1 17 5.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.15 EGD93160.1 - 0.11 11.1 0.0 5.2 5.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Acetyltransf_8 PF13523.1 EGD93162.1 - 4.8e-43 146.6 0.9 7.3e-43 146.0 0.6 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGD93162.1 - 0.029 14.5 0.1 0.048 13.8 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CLASP_N PF12348.3 EGD93163.1 - 4.3e-150 497.3 3.6 4.6e-91 304.2 0.0 2.9 3 1 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EGD93163.1 - 8.5e-08 31.6 0.2 1.5 9.0 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EGD93163.1 - 5.1e-05 23.4 1.0 0.0042 17.3 0.1 4.4 4 1 1 5 5 5 1 HEAT repeats Cnd1 PF12717.2 EGD93163.1 - 0.00028 20.8 0.2 0.0068 16.2 0.0 3.2 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 BSP PF04450.7 EGD93164.1 - 1.4e-64 217.3 0.0 1.6e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EGD93164.1 - 0.0009 19.2 0.0 0.0024 17.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase MA superfamily SprT-like PF10263.4 EGD93164.1 - 0.039 13.5 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 SprT-like family Ribonucleas_3_3 PF14622.1 EGD93166.1 - 5.1e-07 29.6 0.0 0.0059 16.5 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 EGD93166.1 - 7.1e-06 26.5 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EGD93166.1 - 3.6e-05 24.1 0.0 7.2e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease III domain ATP12 PF07542.6 EGD93166.1 - 0.013 15.4 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 ATP12 chaperone protein PfkB PF00294.19 EGD93168.1 - 9.6e-11 41.3 0.0 1.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase FTO_CTD PF12934.2 EGD93168.1 - 0.048 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 FTO C-terminal domain CAP_N PF01213.14 EGD93169.1 - 8.4e-62 209.2 0.4 1.6e-61 208.3 0.3 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EGD93169.1 - 5.7e-54 181.7 1.9 7.5e-54 181.3 1.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EGD93169.1 - 0.0063 15.9 3.3 0.19 11.1 1.7 2.2 1 1 1 2 2 2 2 Tubulin binding cofactor C Ribosomal_60s PF00428.14 EGD93169.1 - 0.07 13.5 0.8 0.07 13.5 0.5 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4210 PF13915.1 EGD93170.1 - 1.4e-27 95.7 0.1 3.8e-27 94.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EGD93170.1 - 3.8e-21 74.6 1.0 7.3e-21 73.7 0.2 1.9 2 0 0 2 2 2 1 Chromosome segregation during meiosis Serglycin PF04360.7 EGD93171.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Serglycin rRNA_processing PF08524.6 EGD93171.1 - 0.086 12.6 27.4 0.072 12.8 9.0 2.7 2 1 0 2 2 2 0 rRNA processing Spc97_Spc98 PF04130.8 EGD93172.1 - 5.4e-57 193.3 0.1 7.2e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Eaf7 PF07904.8 EGD93173.1 - 1.7e-29 101.5 0.0 2.8e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Iso_dh PF00180.15 EGD93174.1 - 1.9e-100 336.1 0.0 2.4e-100 335.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sec5 PF15469.1 EGD93175.1 - 3.1e-33 115.0 0.0 2.4e-32 112.1 0.0 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EGD93175.1 - 1e-05 25.2 0.2 3.6e-05 23.5 0.2 2.0 1 0 0 1 1 1 1 Vps51/Vps67 Mo-co_dimer PF03404.11 EGD93176.1 - 6.2e-55 184.3 0.3 1.2e-54 183.4 0.2 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EGD93176.1 - 2.8e-48 163.5 0.0 4.5e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_1 PF00175.16 EGD93176.1 - 6.4e-24 84.6 0.0 4.7e-23 81.8 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EGD93176.1 - 2.9e-22 78.2 0.0 6e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 EGD93176.1 - 5.9e-15 55.2 0.0 1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGD93176.1 - 0.00043 20.2 0.1 0.0076 16.1 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain PI-PLC-X PF00388.14 EGD93182.1 - 1.3e-56 190.0 0.0 2.8e-56 188.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EGD93182.1 - 4.1e-40 136.4 0.1 8.4e-40 135.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EGD93182.1 - 4.1e-06 26.5 0.0 1e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.6 EGD93182.1 - 1e-05 25.4 0.1 3e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.1 EGD93182.1 - 0.0024 17.4 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair GDPD PF03009.12 EGD93182.1 - 0.053 13.0 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family AhpC-TSA_2 PF13911.1 EGD93183.1 - 6.8e-11 42.1 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGD93183.1 - 0.0041 16.8 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Brix PF04427.13 EGD93184.1 - 9.1e-47 159.1 0.1 1.1e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Brix domain AAA_12 PF13087.1 EGD93185.1 - 2.8e-58 196.6 0.0 4.5e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGD93185.1 - 3.3e-56 190.5 3.0 4.8e-56 189.9 2.0 1.3 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.5 EGD93185.1 - 3.2e-48 163.1 0.7 5.7e-47 159.1 0.0 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_19 PF13245.1 EGD93185.1 - 2.8e-13 49.3 0.4 6.1e-13 48.3 0.3 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGD93185.1 - 1.1e-10 41.3 0.3 1.6e-09 37.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EGD93185.1 - 2e-08 34.2 0.0 3.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EGD93185.1 - 0.00016 21.3 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EGD93185.1 - 0.00038 20.0 0.1 0.97 8.8 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EGD93185.1 - 0.002 17.1 1.8 0.0065 15.4 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EGD93185.1 - 0.014 14.9 0.3 0.033 13.6 0.2 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.16 EGD93185.1 - 0.018 14.3 0.1 0.24 10.6 0.0 2.3 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 EGD93185.1 - 0.02 13.8 0.0 4.7 6.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Ribosomal_S13_N PF08069.7 EGD93185.1 - 0.024 14.4 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.1 EGD93185.1 - 0.04 14.0 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGD93185.1 - 0.052 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.17 EGD93185.1 - 0.056 12.8 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EGD93185.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EGD93185.1 - 0.19 10.8 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 KaiC PTCB-BRCT PF12738.2 EGD93186.1 - 1.1e-08 34.7 0.1 2.4e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EGD93186.1 - 4.5e-07 29.9 0.0 1.6e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.10 EGD93186.1 - 0.0004 20.2 0.0 0.00092 19.1 0.0 1.5 1 0 0 1 1 1 1 WGR domain IGPS PF00218.16 EGD93187.1 - 4.1e-95 317.6 0.0 1.2e-94 316.0 0.0 1.7 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EGD93187.1 - 5.1e-52 176.2 0.1 2.4e-48 164.3 0.0 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EGD93187.1 - 5.3e-51 172.8 0.0 8.9e-51 172.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGD93187.1 - 0.00033 20.1 0.1 0.0017 17.8 0.0 2.1 2 1 0 2 2 2 1 Peptidase C26 His_biosynth PF00977.16 EGD93187.1 - 0.0083 15.4 0.1 0.054 12.7 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein QRPTase_C PF01729.14 EGD93187.1 - 0.0091 15.5 0.3 0.52 9.8 0.0 2.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 EGD93187.1 - 0.12 11.3 0.4 0.34 9.8 0.0 2.0 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Nup188 PF10487.4 EGD93188.1 - 2.4e-54 184.6 3.1 2.8e-53 181.1 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 DUF465 PF04325.8 EGD93188.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) AMP-binding PF00501.23 EGD93189.1 - 1.3e-64 218.1 0.0 4.3e-46 157.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EGD93189.1 - 3.2e-11 44.0 0.0 6.5e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_7 PF13508.1 EGD93192.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD93192.1 - 0.0064 16.4 0.0 0.023 14.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGD93192.1 - 0.0092 16.0 0.0 0.051 13.6 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Use1 PF09753.4 EGD93193.1 - 3.8e-09 36.3 10.6 2.6e-08 33.6 7.4 2.2 1 1 0 1 1 1 1 Membrane fusion protein Use1 Macoilin PF09726.4 EGD93193.1 - 2.4 6.3 19.7 3.8 5.6 13.4 1.5 1 1 0 1 1 1 0 Transmembrane protein DUF3573 PF12097.3 EGD93193.1 - 5.2 5.5 8.3 0.23 10.0 1.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) ARA70 PF12489.3 EGD93193.1 - 7 6.6 11.8 0.37 10.7 3.3 2.2 2 0 0 2 2 2 0 Nuclear coactivator G-alpha PF00503.15 EGD93194.1 - 3.7e-118 394.6 5.3 1.1e-101 340.3 0.1 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 EGD93194.1 - 4.3e-13 48.8 1.0 1.8e-10 40.3 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EGD93194.1 - 6.7e-05 22.3 0.0 0.00029 20.3 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EGD93194.1 - 0.13 12.8 0.0 3.7 8.0 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein CH PF00307.26 EGD93196.1 - 6.3e-38 129.1 0.1 5.2e-20 71.5 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EGD93196.1 - 3.1e-26 91.1 0.1 7.8e-26 89.8 0.1 1.7 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EGD93196.1 - 3.6e-11 42.5 1.0 7.6e-08 31.9 0.0 3.1 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_8 PF13833.1 EGD93196.1 - 0.0021 17.6 0.1 0.011 15.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EGD93196.1 - 0.0026 17.5 0.0 0.018 14.8 0.0 2.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 EGD93196.1 - 0.018 14.3 0.1 0.18 11.2 0.0 2.6 2 0 0 2 2 2 0 EF hand DUF4646 PF15496.1 EGD93196.1 - 0.052 13.6 0.0 1.4 9.0 0.0 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4646) Spectrin PF00435.16 EGD93196.1 - 0.26 11.5 10.3 0.86 9.9 0.0 3.1 3 1 0 3 3 3 0 Spectrin repeat EB PF01683.13 EGD93199.1 - 0.027 14.5 4.9 0.027 14.5 3.4 4.7 1 1 2 3 3 3 0 EB module Dickkopf_N PF04706.7 EGD93199.1 - 0.035 14.2 12.0 0.035 14.2 8.3 4.5 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region Ribosomal_S16 PF00886.14 EGD93200.1 - 2.3e-24 84.8 0.1 3.2e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.10 EGD93201.1 - 3.4e-38 130.9 0.0 4.1e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PUL PF08324.6 EGD93202.1 - 1e-58 198.3 0.0 1.3e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 EGD93202.1 - 2.7e-37 125.2 21.4 7.6e-09 35.1 0.1 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat PFU PF09070.6 EGD93202.1 - 5.4e-29 100.5 0.1 1.4e-28 99.2 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EGD93203.1 - 4.2e-14 51.7 1.3 1.1e-09 37.7 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Cap_synth_GfcB PF11102.3 EGD93203.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Group 4 capsule polysaccharide formation lipoprotein gfcB RRM_1 PF00076.17 EGD93204.1 - 2e-16 59.3 0.0 3.5e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD93204.1 - 1.5e-12 47.2 0.0 2.5e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EGD93204.1 - 7.7e-07 29.4 7.7 7.7e-07 29.4 5.3 4.1 4 0 0 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EGD93204.1 - 8.4e-06 25.5 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bot1p PF12298.3 EGD93205.1 - 1.5e-57 194.2 0.6 1.5e-57 194.2 0.4 1.8 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein HTH_Tnp_ISL3 PF13542.1 EGD93205.1 - 0.084 12.0 0.0 0.23 10.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Pkinase PF00069.20 EGD93207.1 - 6.9e-56 189.2 0.0 9.9e-56 188.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93207.1 - 4.7e-25 88.1 0.0 1.2e-24 86.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD93207.1 - 0.0015 17.5 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RNA_pol_3_Rpc31 PF11705.3 EGD93208.1 - 0.038 13.9 6.9 0.045 13.6 4.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nucleoplasmin PF03066.10 EGD93208.1 - 0.086 12.3 5.9 0.077 12.5 4.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 EGD93208.1 - 0.23 10.1 7.9 0.24 10.0 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.1 EGD93208.1 - 1.8 8.2 6.5 2.5 7.7 4.5 1.2 1 0 0 1 1 1 0 FAM176 family Myc_N PF01056.13 EGD93208.1 - 2.2 7.3 7.3 2.5 7.1 5.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 EGD93208.1 - 6.9 6.9 16.8 37 4.6 12.2 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BLVR PF06375.6 EGD93209.1 - 1.6 8.5 10.3 2 8.2 7.2 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RRP14 PF15459.1 EGD93209.1 - 3.2 7.9 14.7 4.5 7.4 10.2 1.2 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Nucleoplasmin PF03066.10 EGD93210.1 - 0.001 18.5 6.1 0.0011 18.5 4.2 1.1 1 0 0 1 1 1 1 Nucleoplasmin BSP_II PF05432.6 EGD93210.1 - 0.0011 18.3 5.8 0.0012 18.1 4.0 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) TFIIA PF03153.8 EGD93210.1 - 0.0028 17.5 5.5 0.0028 17.5 3.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.7 EGD93210.1 - 0.018 14.3 7.0 0.022 14.0 4.9 1.0 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.8 EGD93210.1 - 0.019 14.6 8.5 0.024 14.2 5.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 EGD93210.1 - 0.031 14.5 13.1 0.053 13.8 9.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CobT PF06213.7 EGD93210.1 - 0.069 12.2 5.2 0.069 12.2 3.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.1 EGD93210.1 - 0.069 12.8 4.7 0.094 12.4 3.3 1.2 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.7 EGD93210.1 - 0.084 10.7 7.8 0.085 10.7 5.4 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EGD93210.1 - 0.11 11.7 4.2 0.11 11.7 2.9 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 EGD93210.1 - 0.15 11.8 7.3 0.2 11.4 5.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal FLO_LFY PF01698.11 EGD93210.1 - 0.17 10.7 1.0 0.18 10.6 0.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein VID27 PF08553.5 EGD93210.1 - 0.51 8.5 3.6 0.5 8.5 2.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein RNA_pol_3_Rpc31 PF11705.3 EGD93210.1 - 0.6 10.0 11.5 0.76 9.6 8.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Mpp10 PF04006.7 EGD93210.1 - 1.6 6.9 12.4 1.8 6.8 8.6 1.0 1 0 0 1 1 1 0 Mpp10 protein Nucleo_P87 PF07267.6 EGD93210.1 - 2.1 6.9 4.9 2.4 6.7 3.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 EGD93210.1 - 2.8 5.8 8.7 3.5 5.5 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 EGD93210.1 - 4 6.2 6.2 5 5.9 4.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Myc_N PF01056.13 EGD93210.1 - 4.1 6.4 10.0 5.2 6.1 7.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 EGD93210.1 - 4.8 7.4 17.5 7.7 6.8 12.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tom22 PF04281.8 EGD93210.1 - 7.3 6.1 8.3 9.4 5.7 5.7 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Daxx PF03344.10 EGD93210.1 - 8.8 4.6 13.7 11 4.4 9.5 1.0 1 0 0 1 1 1 0 Daxx Family AMP-binding PF00501.23 EGD93212.1 - 1.8e-93 313.2 0.0 2.1e-93 312.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD93212.1 - 6.8e-11 42.9 0.3 2.1e-10 41.3 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SET PF00856.23 EGD93213.1 - 5.9e-12 46.1 0.0 1.9e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 SET domain UBA_4 PF14555.1 EGD93214.1 - 2.1e-12 46.3 0.3 4.6e-12 45.2 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain FlaC_arch PF05377.6 EGD93215.1 - 0.13 12.1 0.1 25 4.8 0.0 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) SH3_1 PF00018.23 EGD93216.1 - 1.6e-09 36.9 0.1 2.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD93216.1 - 2.1e-07 30.4 0.0 4.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGD93216.1 - 7.5e-07 28.5 0.0 1.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain YhhN PF07947.9 EGD93216.1 - 0.16 11.3 8.8 0.22 10.8 6.1 1.1 1 0 0 1 1 1 0 YhhN-like protein Response_reg PF00072.19 EGD93217.1 - 1.8e-21 76.1 0.0 7.7e-14 51.6 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain DUF2052 PF09747.4 EGD93218.1 - 1.2e-29 103.5 11.3 3.6e-29 101.9 7.9 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Spermine_synth PF01564.12 EGD93219.1 - 3.6e-06 26.0 0.1 6.1e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EGD93219.1 - 0.00013 22.0 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 EGD93219.1 - 0.036 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.1 EGD93219.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Y_phosphatase3 PF13350.1 EGD93220.1 - 5.2e-48 163.4 0.0 9.5e-48 162.5 0.0 1.4 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGD93220.1 - 2.2e-11 43.7 0.2 1.5e-10 41.0 0.0 2.4 2 1 1 3 3 3 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EGD93220.1 - 0.0053 16.1 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Lysis_col PF02402.11 EGD93220.1 - 0.013 15.0 0.4 0.028 13.9 0.2 1.4 1 0 0 1 1 1 0 Lysis protein Y_phosphatase PF00102.22 EGD93220.1 - 0.019 14.2 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGD93220.1 - 0.042 13.9 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Peptidase_C12 PF01088.16 EGD93221.1 - 3.1e-56 189.9 0.0 3.7e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 EGD93221.1 - 0.045 14.3 0.0 0.076 13.6 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain Peptidase_S9 PF00326.16 EGD93223.1 - 2.3e-49 167.4 0.4 4.9e-49 166.4 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family PD40 PF07676.7 EGD93223.1 - 2.2e-09 36.7 1.5 0.011 15.3 0.0 4.8 4 0 0 4 4 4 4 WD40-like Beta Propeller Repeat Abhydrolase_5 PF12695.2 EGD93223.1 - 4.6e-07 29.6 0.0 8.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLIC PF05783.6 EGD93224.1 - 9.3e-32 110.3 4.9 1.5e-27 96.4 0.0 3.9 2 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) Myb_CC_LHEQLE PF14379.1 EGD93224.1 - 0.034 13.7 3.1 0.08 12.5 2.2 1.6 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif RRM_1 PF00076.17 EGD93225.1 - 7.7e-20 70.3 0.5 2.2e-19 68.8 0.0 2.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD93225.1 - 3.9e-14 52.3 0.0 1.2e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD93225.1 - 3.4e-06 26.8 0.0 6.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EGD93225.1 - 1.2 8.6 0.0 1.2 8.6 0.0 3.0 3 1 0 3 3 3 0 Ribonuclease B OB domain WD40 PF00400.27 EGD93226.1 - 7.1e-08 32.0 0.1 0.00076 19.2 0.1 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat Gmad1 PF10647.4 EGD93226.1 - 0.056 12.8 0.4 2.4 7.5 0.0 2.7 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 EGD93226.1 - 0.092 11.8 0.0 0.51 9.3 0.0 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Septin PF00735.13 EGD93227.1 - 3.5e-107 357.6 0.3 5.7e-107 356.9 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EGD93227.1 - 4.9e-05 23.2 0.0 9.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGD93227.1 - 0.00099 18.9 5.0 0.47 10.2 0.0 3.1 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EGD93227.1 - 0.0014 17.7 0.3 0.0037 16.4 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGD93227.1 - 0.0034 16.8 0.0 0.071 12.5 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EGD93227.1 - 0.013 14.5 0.0 0.033 13.2 0.0 1.7 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 EGD93227.1 - 0.017 15.6 0.1 0.057 13.9 0.0 2.0 2 0 0 2 2 1 0 Miro-like protein AAA_24 PF13479.1 EGD93227.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF390 PF04094.9 EGD93227.1 - 0.043 11.8 4.4 0.059 11.4 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) AAA_22 PF13401.1 EGD93227.1 - 0.048 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 EGD93227.1 - 0.062 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EGD93227.1 - 0.15 12.3 1.3 0.79 10.0 0.0 2.5 2 1 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 EGD93227.1 - 0.19 11.1 0.1 0.19 11.1 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family FMN_bind PF04205.9 EGD93227.1 - 0.22 11.7 0.8 0.68 10.1 0.0 2.1 2 0 0 2 2 2 0 FMN-binding domain DUF3653 PF12375.3 EGD93227.1 - 0.49 10.6 3.0 11 6.3 1.2 2.9 2 1 0 2 2 2 0 Phage protein AAA_17 PF13207.1 EGD93227.1 - 1.8 9.4 5.7 0.58 10.9 0.1 2.6 2 2 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 EGD93227.1 - 9 4.0 6.6 14 3.3 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CNH PF00780.17 EGD93228.1 - 2.2e-82 276.6 0.0 1.1e-81 274.3 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EGD93228.1 - 4.3e-39 133.5 0.0 9.7e-39 132.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EGD93228.1 - 2.5e-38 131.7 0.0 4.4e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EGD93228.1 - 6.8e-13 48.1 0.0 1.6e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.16 EGD93229.1 - 3.4e-22 78.1 35.1 1.9e-15 56.5 7.0 2.8 2 1 0 2 2 2 2 ATP synthase subunit C Pkinase PF00069.20 EGD93230.1 - 6.8e-61 205.6 0.0 9.8e-61 205.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93230.1 - 4.9e-34 117.5 0.0 6.7e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD93230.1 - 0.00014 20.9 0.0 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EGD93230.1 - 0.017 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PyrBI_leader PF08052.6 EGD93230.1 - 0.024 14.4 0.1 4.1 7.2 0.0 2.6 2 0 0 2 2 2 0 PyrBI operon leader peptide Kdo PF06293.9 EGD93230.1 - 0.05 12.6 0.0 0.093 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD93230.1 - 0.061 13.0 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGD93230.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gly_transf_sug PF04488.10 EGD93231.1 - 1.1e-13 51.3 0.0 2.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Trypan_PARP PF05887.6 EGD93231.1 - 0.01 15.6 8.6 0.017 14.9 6.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Abhydrolase_1 PF00561.15 EGD93233.1 - 4.7e-16 59.0 0.1 7.6e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGD93233.1 - 4.8e-07 29.9 0.0 7.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGD93233.1 - 0.00025 20.5 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase EphA2_TM PF14575.1 EGD93234.1 - 0.068 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pol_alpha_B_N PF08418.5 EGD93235.1 - 4.5 6.7 8.9 5.7 6.4 6.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Kisspeptin PF15152.1 EGD93235.1 - 6.1 7.6 6.9 1.7 9.4 0.7 2.2 2 1 0 2 2 2 0 Kisspeptin GSHPx PF00255.14 EGD93236.1 - 5.5e-39 131.8 0.0 7.5e-39 131.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EGD93236.1 - 0.023 14.3 0.0 0.063 12.9 0.0 1.8 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 EGD93236.1 - 0.032 13.7 0.2 0.16 11.5 0.1 2.0 1 1 0 1 1 1 0 Redoxin Ral PF11058.3 EGD93236.1 - 0.099 12.0 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral SCO1-SenC PF02630.9 EGD93236.1 - 0.12 11.9 0.0 0.53 9.8 0.0 1.9 2 0 0 2 2 2 0 SCO1/SenC RR_TM4-6 PF06459.7 EGD93237.1 - 0.032 14.1 3.5 0.034 14.0 2.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ORC6 PF05460.8 EGD93237.1 - 0.29 10.2 8.7 0.33 9.9 6.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hydrolase_6 PF13344.1 EGD93238.1 - 8e-24 83.4 0.0 1.7e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD93238.1 - 1.9e-09 37.1 0.0 1.3e-08 34.3 0.0 2.5 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 EGD93238.1 - 0.12 12.7 0.0 0.71 10.2 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF676 PF05057.9 EGD93239.1 - 3.2e-48 163.8 0.0 4.9e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EGD93239.1 - 4.2e-06 26.5 0.0 7.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EGD93239.1 - 7.3e-05 22.4 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EGD93239.1 - 0.0075 16.1 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EGD93239.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 PE-PPE domain PGAP1 PF07819.8 EGD93239.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.6 EGD93239.1 - 0.016 14.3 0.0 4.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) RNase_T PF00929.19 EGD93240.1 - 9e-09 35.8 0.0 3.1e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Exonuclease BTK PF00779.14 EGD93240.1 - 0.077 12.6 0.6 0.15 11.6 0.4 1.5 1 0 0 1 1 1 0 BTK motif Ribosomal_L22e PF01776.12 EGD93241.1 - 2.5e-49 165.9 0.7 3.1e-49 165.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Translin PF01997.11 EGD93242.1 - 9.5e-54 182.0 0.0 1.1e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 Translin family HR1 PF02185.11 EGD93242.1 - 0.033 13.9 0.2 0.09 12.5 0.2 1.7 1 0 0 1 1 1 0 Hr1 repeat DisA-linker PF10635.4 EGD93242.1 - 0.042 13.3 0.3 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 DisA bacterial checkpoint controller linker region Herpes_UL25 PF01499.11 EGD93242.1 - 0.05 11.9 0.0 0.074 11.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Syntaxin PF00804.20 EGD93242.1 - 0.059 13.5 1.5 0.65 10.1 0.4 2.3 2 0 0 2 2 2 0 Syntaxin Ribosomal_L29 PF00831.18 EGD93242.1 - 0.072 12.7 0.6 7.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Ribosomal L29 protein DUF1938 PF09153.5 EGD93242.1 - 0.11 12.3 0.2 1 9.2 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1938) Pcc1 PF09341.5 EGD93243.1 - 1.1e-23 83.0 3.0 3.4e-23 81.4 2.1 1.7 1 1 0 1 1 1 1 Transcription factor Pcc1 Gemini_C4 PF01492.12 EGD93243.1 - 0.072 12.8 0.6 0.1 12.3 0.4 1.3 1 0 0 1 1 1 0 Geminivirus C4 protein Cep57_CLD PF14073.1 EGD93243.1 - 0.11 12.3 0.2 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DSPn PF14671.1 EGD93245.1 - 1.2e-40 138.7 0.0 1.2e-37 129.0 0.0 3.1 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EGD93245.1 - 1e-15 57.5 0.0 2.7e-15 56.1 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD93245.1 - 2.1e-05 23.9 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase YonK PF09642.5 EGD93245.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 YonK protein Pyridoxal_deC PF00282.14 EGD93247.1 - 2.8e-28 98.4 0.0 3.8e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Pyridoxal_deC PF00282.14 EGD93248.1 - 1.1e-08 34.0 0.1 1.3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SnoaL_4 PF13577.1 EGD93248.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain DUF917 PF06032.7 EGD93249.1 - 4.5e-63 212.9 0.4 2.4e-31 108.5 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EGD93249.1 - 1.7e-54 184.8 7.0 3.3e-53 180.6 1.6 2.7 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGD93249.1 - 4.6e-27 94.6 6.5 5e-26 91.2 0.1 2.8 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EGD93249.1 - 1.7e-05 23.3 2.2 0.0093 14.3 0.3 2.4 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 EGD93249.1 - 0.0018 17.6 1.4 0.063 12.5 0.1 3.0 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 EGD93249.1 - 0.047 13.5 1.0 10 6.0 0.0 3.1 2 0 0 2 2 2 0 Cell division protein FtsA StbA PF06406.6 EGD93249.1 - 0.11 11.3 0.7 4.9 5.9 0.3 2.4 2 0 0 2 2 2 0 StbA protein Homeobox PF00046.24 EGD93250.1 - 7.7e-14 51.0 1.2 2.1e-13 49.6 0.8 1.8 1 0 0 1 1 1 1 Homeobox domain MFS_1 PF07690.11 EGD93251.1 - 2.1e-41 141.8 10.1 8.7e-34 116.7 8.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD93251.1 - 6.7e-11 41.4 9.7 4.3e-08 32.1 2.8 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EGD93251.1 - 5e-07 28.1 5.0 0.0011 17.0 1.3 2.8 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EGD93251.1 - 4.2e-05 21.8 2.2 0.016 13.3 1.6 2.9 2 1 1 3 3 3 2 Transmembrane secretion effector MscS_TM PF12794.2 EGD93251.1 - 0.0016 17.1 0.1 0.0059 15.2 0.0 2.0 1 1 1 2 2 2 1 Mechanosensitive ion channel inner membrane domain 1 Fungal_trans_2 PF11951.3 EGD93252.1 - 7.5e-51 172.9 0.1 1e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD93252.1 - 9.5e-08 31.8 9.8 9.5e-08 31.8 6.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EGD93253.1 - 1.7e-56 191.3 0.2 1.8e-55 187.9 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93253.1 - 5.8e-29 100.9 0.6 2.5e-20 72.6 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EGD93253.1 - 3.1e-06 27.5 0.4 6.9e-06 26.4 0.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGD93253.1 - 4.6e-05 22.5 0.1 0.00041 19.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGD93253.1 - 0.00077 19.2 3.1 0.31 10.7 0.0 3.4 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD93253.1 - 0.05 12.6 0.0 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1687 PF07955.6 EGD93254.1 - 1.3e-13 51.0 0.1 6.4e-13 48.8 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Abhydrolase_2 PF02230.11 EGD93255.1 - 2.4e-56 190.5 0.0 2.8e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGD93255.1 - 3.2e-10 39.9 0.0 6e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGD93255.1 - 1.8e-08 33.8 0.1 1.2e-05 24.6 0.0 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 EGD93255.1 - 3e-06 26.7 0.0 4.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EGD93255.1 - 2e-05 24.2 0.0 0.0096 15.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 EGD93255.1 - 2.9e-05 23.5 0.0 9.2e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EGD93255.1 - 0.00015 21.7 0.0 0.16 11.8 0.0 2.7 1 1 1 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EGD93255.1 - 0.038 13.4 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 EGD93255.1 - 0.057 13.0 0.0 0.096 12.3 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 3) DUF2920 PF11144.3 EGD93255.1 - 0.13 11.2 0.0 2.2 7.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Esterase_phd PF10503.4 EGD93255.1 - 0.14 11.4 0.0 0.81 8.8 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase CD99L2 PF12301.3 EGD93256.1 - 1.1 8.9 5.2 1.7 8.3 3.6 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 Ctr PF04145.10 EGD93257.1 - 2.3e-28 99.0 0.0 3.2e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family FAD_binding_8 PF08022.7 EGD93258.1 - 2.9e-20 72.0 0.0 6.7e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EGD93258.1 - 3.9e-18 65.8 0.0 1.6e-17 63.8 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EGD93258.1 - 2.1e-13 50.4 11.3 6.7e-13 48.8 7.8 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGD93258.1 - 0.00038 20.5 0.0 0.0027 17.7 0.0 2.3 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGD93258.1 - 0.013 16.0 0.0 3 8.4 0.0 2.9 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain FAD_binding_3 PF01494.14 EGD93259.1 - 3.6e-70 236.7 0.1 4.8e-68 229.8 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGD93259.1 - 1.6e-20 73.3 0.0 1.5e-19 70.2 0.0 2.3 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EGD93259.1 - 0.011 14.5 0.0 0.039 12.7 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.9 EGD93259.1 - 0.068 11.7 0.1 0.13 10.8 0.0 1.4 2 0 0 2 2 2 0 Tryptophan halogenase Nup35_RRM PF05172.8 EGD93260.1 - 0.0012 18.5 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif IncA PF04156.9 EGD93261.1 - 9e-05 22.1 0.4 0.00012 21.7 0.3 1.1 1 0 0 1 1 1 1 IncA protein PLU-1 PF08429.6 EGD93261.1 - 0.034 13.0 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 PLU-1-like protein HrpJ PF07201.6 EGD93261.1 - 0.089 12.8 2.2 8.4 6.3 0.3 2.2 1 1 0 2 2 2 0 HrpJ-like domain BLOC1_2 PF10046.4 EGD93261.1 - 0.096 12.8 0.2 0.19 11.8 0.1 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Wbp11 PF09429.5 EGD93263.1 - 8.7e-23 80.1 18.6 1.2e-22 79.6 11.9 2.0 2 0 0 2 2 2 1 WW domain binding protein 11 SynMuv_product PF06047.6 EGD93263.1 - 0.19 11.4 0.1 0.19 11.4 0.1 2.5 2 1 0 2 2 2 0 Ras-induced vulval development antagonist DUF294_C PF10335.4 EGD93263.1 - 0.59 9.7 5.4 1.3 8.6 3.4 1.8 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain Pkinase PF00069.20 EGD93265.1 - 1.1e-58 198.4 0.0 2e-58 197.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93265.1 - 1.2e-36 126.1 0.0 1.2e-35 122.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Reo_sigmaC PF04582.7 EGD93265.1 - 0.12 11.5 0.4 0.18 10.9 0.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF607 PF04678.8 EGD93265.1 - 1.1 9.2 5.2 0.75 9.6 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF607 BTB PF00651.26 EGD93266.1 - 4.3e-27 94.2 0.0 1.9e-13 50.3 0.2 2.8 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 EGD93266.1 - 7e-08 32.7 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGD93266.1 - 6.4e-07 28.8 0.2 2.9e-06 26.8 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EGD93266.1 - 8.4e-07 29.3 0.0 2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD93266.1 - 2.4e-05 24.4 0.1 0.0001 22.4 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD93266.1 - 0.0025 17.9 0.1 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat TRP PF06011.7 EGD93267.1 - 5.8e-66 222.8 23.1 1.6e-65 221.3 16.1 1.5 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGD93267.1 - 1.1e-21 77.3 0.0 1.8e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 ML-like domain zf-C2H2 PF00096.21 EGD93273.1 - 5e-09 35.9 11.3 0.00038 20.6 1.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD93273.1 - 2.8e-06 27.3 9.6 6.3e-06 26.2 0.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGD93273.1 - 0.00016 21.7 9.8 0.0084 16.3 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EGD93273.1 - 0.012 15.8 2.9 0.025 14.7 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EGD93273.1 - 0.14 12.1 1.6 3.6 7.6 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 EGD93273.1 - 0.37 10.9 5.2 0.65 10.2 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EGD93273.1 - 1.5 8.6 9.1 2.8 7.7 1.3 2.6 2 1 0 2 2 2 0 BED zinc finger adh_short PF00106.20 EGD93274.1 - 9e-15 54.9 0.0 1.2e-13 51.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD93274.1 - 1e-08 35.0 0.0 1.9e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD93274.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EGD93274.1 - 0.0026 16.7 0.0 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGD93274.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EGD93274.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAC PF01849.13 EGD93275.1 - 8.3e-23 79.6 0.4 1.6e-22 78.7 0.3 1.5 1 0 0 1 1 1 1 NAC domain Sigma70_ner PF04546.8 EGD93275.1 - 0.46 10.0 3.9 0.95 9.0 0.8 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Rpr2 PF04032.11 EGD93276.1 - 1.5e-21 76.0 3.9 6.8e-21 73.9 2.7 1.9 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.11 EGD93276.1 - 0.066 13.1 0.9 0.097 12.6 0.5 1.3 1 1 0 1 1 1 0 Mut7-C RNAse domain DEAD PF00270.24 EGD93277.1 - 1.5e-26 92.9 0.0 2.2e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD93277.1 - 4.2e-25 87.4 0.1 1.9e-23 82.0 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EGD93277.1 - 0.00037 19.6 0.1 0.0036 16.4 0.0 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 EGD93277.1 - 0.0026 17.6 0.0 0.0065 16.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ank_2 PF12796.2 EGD93278.1 - 1.2e-28 99.2 10.2 1e-10 41.7 0.1 5.1 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD93278.1 - 8.7e-23 80.2 13.3 1e-06 29.0 0.1 7.8 4 3 5 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD93278.1 - 1.5e-21 75.8 7.4 5.7e-07 29.5 0.0 5.5 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EGD93278.1 - 3.6e-19 67.5 5.5 5.6e-06 25.8 0.1 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 EGD93278.1 - 4.6e-15 54.2 3.4 0.00037 20.4 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat ApbA PF02558.11 EGD93279.1 - 1.2e-24 86.4 0.0 2e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EGD93279.1 - 5.5e-22 78.0 0.0 9.2e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.6 EGD93280.1 - 3.7e-20 71.8 4.1 4.9e-20 71.4 2.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like BBS2_C PF14782.1 EGD93281.1 - 0.0054 15.3 1.9 0.0065 15.0 1.3 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal Angiomotin_C PF12240.3 EGD93281.1 - 0.0084 15.6 2.6 0.011 15.2 1.8 1.1 1 0 0 1 1 1 1 Angiomotin C terminal L31 PF09784.4 EGD93281.1 - 0.029 14.4 0.4 0.038 14.0 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF3450 PF11932.3 EGD93281.1 - 0.084 12.1 6.1 0.098 11.9 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1465 PF07323.7 EGD93281.1 - 0.14 11.7 2.3 0.17 11.4 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Peptidase_S49 PF01343.13 EGD93281.1 - 0.74 9.5 3.6 0.75 9.5 1.7 1.5 1 1 0 1 1 1 0 Peptidase family S49 FlxA PF14282.1 EGD93281.1 - 9.4 6.2 14.3 19 5.2 9.9 1.5 1 1 0 1 1 1 0 FlxA-like protein Lipase_3 PF01764.20 EGD93282.1 - 2.8e-16 59.4 0.0 2e-15 56.6 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGD93282.1 - 0.015 15.0 0.1 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family RGS PF00615.14 EGD93283.1 - 3.5e-06 27.0 0.0 0.0012 18.8 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF2892 PF11127.3 EGD93283.1 - 2.4 8.0 5.8 1.7 8.5 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) SMC_N PF02463.14 EGD93284.1 - 7.6e-22 77.6 0.0 1.4e-21 76.7 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGD93284.1 - 2.5e-14 54.1 57.8 1.7e-12 48.1 17.3 5.5 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EGD93284.1 - 2.1e-05 24.6 0.0 0.0014 18.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGD93284.1 - 0.0013 18.2 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Baculo_PEP_C PF04513.7 EGD93284.1 - 0.014 15.2 11.1 1.4 8.7 0.3 4.5 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_25 PF13481.1 EGD93284.1 - 0.15 11.4 0.0 0.15 11.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EGD93284.1 - 0.37 11.1 0.0 0.37 11.1 0.0 4.3 4 1 0 4 4 4 0 ABC transporter AAA_13 PF13166.1 EGD93284.1 - 1.9 6.8 63.1 0.29 9.5 0.0 4.5 3 2 0 3 3 3 0 AAA domain Reo_sigmaC PF04582.7 EGD93284.1 - 8.3 5.4 17.6 4.2 6.4 1.4 3.8 2 1 1 3 3 3 0 Reovirus sigma C capsid protein AdoMet_MTase PF07757.8 EGD93285.1 - 2.8e-36 124.0 0.0 1e-18 67.4 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase DUF3237 PF11578.3 EGD93286.1 - 9.9e-35 119.0 0.0 1.5e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 EGD93286.1 - 3.3e-07 29.9 2.9 0.0077 15.9 0.3 2.3 2 0 0 2 2 2 2 BED zinc finger FimP PF09766.4 EGD93286.1 - 0.11 11.5 8.1 0.17 10.8 5.6 1.3 1 0 0 1 1 1 0 Fms-interacting protein Activator_LAG-3 PF11498.3 EGD93286.1 - 0.11 11.2 23.5 0.24 10.0 16.3 1.6 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.8 EGD93286.1 - 0.21 11.4 23.4 0.29 10.9 16.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.3 EGD93286.1 - 0.27 10.5 5.3 0.52 9.6 3.7 1.4 1 0 0 1 1 1 0 Spt20 family vMSA PF00695.14 EGD93286.1 - 2.3 7.3 5.4 3.7 6.6 3.8 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus BAF1_ABF1 PF04684.8 EGD93286.1 - 2.4 6.8 15.8 4.3 6.0 10.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDK5_activator PF03261.10 EGD93286.1 - 4.6 6.4 11.0 8.9 5.5 7.6 1.5 1 1 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Gln-synt_C PF00120.19 EGD93287.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain adh_short PF00106.20 EGD93289.1 - 5e-29 101.3 1.0 6.9e-29 100.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD93289.1 - 1.1e-17 64.6 0.0 1.4e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD93289.1 - 1.5e-11 44.2 0.7 2.6e-11 43.5 0.5 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EGD93289.1 - 9.4e-05 22.1 0.2 0.00018 21.2 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EGD93289.1 - 0.0011 18.4 0.1 0.0018 17.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 EGD93289.1 - 0.0091 16.5 0.0 0.061 13.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 EGD93289.1 - 0.017 14.0 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EGD93289.1 - 0.044 13.5 2.7 0.45 10.3 0.3 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EGD93289.1 - 0.054 13.5 1.6 0.13 12.2 0.8 1.9 1 1 0 1 1 1 0 NADH(P)-binding Saccharop_dh PF03435.13 EGD93289.1 - 0.062 12.2 0.2 0.093 11.6 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 EGD93289.1 - 0.071 12.1 0.7 0.13 11.3 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 EGD93289.1 - 0.089 12.6 1.0 0.35 10.6 0.4 2.0 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain BTB PF00651.26 EGD93290.1 - 0.0054 16.7 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain CBP4 PF07960.6 EGD93291.1 - 1.2e-33 115.4 0.7 1.3e-33 115.3 0.5 1.0 1 0 0 1 1 1 1 CBP4 Trp_oprn_chp PF09534.5 EGD93291.1 - 0.077 12.6 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Glyco_hydro_76 PF03663.9 EGD93292.1 - 5.4e-149 496.5 15.1 6.8e-149 496.2 10.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EGD93292.1 - 0.0081 15.2 8.4 0.051 12.6 0.6 3.2 1 1 0 3 3 3 2 Glycosyl Hydrolase Family 88 Rad21_Rec8_N PF04825.8 EGD93293.1 - 2.2e-30 104.8 0.0 3.7e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein DUF4006 PF13179.1 EGD93293.1 - 0.0036 16.8 0.2 0.0074 15.8 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF4006) Rad21_Rec8 PF04824.11 EGD93293.1 - 0.068 12.3 0.1 0.16 11.2 0.1 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein DUF619 PF04768.8 EGD93294.1 - 3.2e-50 169.8 0.1 6.5e-50 168.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EGD93294.1 - 2.9e-30 105.0 0.0 1.1e-29 103.1 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EGD93294.1 - 3.1e-24 85.8 0.0 5.8e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EGD93294.1 - 0.096 12.6 0.0 0.31 10.9 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.16 EGD93295.1 - 5.2e-33 112.5 1.6 6.1e-33 112.2 1.1 1.1 1 0 0 1 1 1 1 Synaptobrevin CDP-OH_P_transf PF01066.16 EGD93295.1 - 0.083 13.1 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase EMP24_GP25L PF01105.19 EGD93295.1 - 0.096 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1035 PF06281.7 EGD93295.1 - 0.18 11.6 1.5 0.33 10.7 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) DUF515 PF04415.7 EGD93295.1 - 0.23 9.6 1.0 0.32 9.1 0.7 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF515) Sel1 PF08238.7 EGD93297.1 - 5.8e-47 157.0 27.6 7.4e-09 35.9 0.6 7.8 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.1 EGD93297.1 - 0.039 14.4 6.7 0.8 10.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGD93297.1 - 0.76 10.5 6.6 4.3 8.2 0.6 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat L51_S25_CI-B8 PF05047.11 EGD93298.1 - 1.1e-13 50.6 0.0 1.4e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 EGD93299.1 - 9.9e-32 109.3 0.0 1.3e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Enoyl_reductase PF12241.3 EGD93299.1 - 0.066 12.1 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region FAD_binding_3 PF01494.14 EGD93300.1 - 1.8e-14 53.5 1.5 8e-14 51.4 1.0 1.8 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EGD93300.1 - 0.022 13.8 0.0 0.048 12.7 0.0 1.5 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase Methyltransf_23 PF13489.1 EGD93301.1 - 5.3e-23 81.4 1.6 7.8e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD93301.1 - 3e-13 50.0 0.0 6.2e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD93301.1 - 1.1e-12 47.8 1.1 7.3e-12 45.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD93301.1 - 3.8e-10 40.1 0.0 1.7e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD93301.1 - 8.2e-10 39.2 0.0 1.2e-08 35.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGD93301.1 - 2.5e-06 26.7 0.0 4.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EGD93301.1 - 1.1e-05 25.3 0.0 2.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD93301.1 - 2.9e-05 23.2 0.0 0.00057 19.0 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGD93301.1 - 3.4e-05 24.1 0.0 0.00011 22.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD93301.1 - 0.00053 19.3 0.0 0.0071 15.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EGD93301.1 - 0.0028 16.8 0.0 0.0089 15.2 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase PrmA PF06325.8 EGD93301.1 - 0.0072 15.4 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EGD93301.1 - 0.0078 15.2 0.6 0.074 12.0 0.0 2.5 3 0 0 3 3 3 1 Putative methyltransferase FtsJ PF01728.14 EGD93301.1 - 0.0089 16.0 0.0 0.019 14.9 0.0 1.5 2 0 0 2 2 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EGD93301.1 - 0.022 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_PK PF05891.7 EGD93301.1 - 0.11 11.7 0.1 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DUF575 PF04746.7 EGD93303.1 - 0.00074 19.5 0.2 0.0013 18.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF575) Podoplanin PF05808.6 EGD93303.1 - 0.00074 19.1 0.7 0.0017 17.9 0.5 1.5 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.1 EGD93303.1 - 0.0011 18.7 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Plasmodium_Vir PF05795.6 EGD93303.1 - 0.0014 17.9 0.1 0.0017 17.6 0.1 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Ashwin PF15323.1 EGD93303.1 - 0.0061 16.5 0.2 0.009 16.0 0.2 1.2 1 0 0 1 1 1 1 Developmental protein DAP10 PF07213.6 EGD93303.1 - 0.012 15.3 1.4 0.31 10.8 0.1 2.3 2 0 0 2 2 2 0 DAP10 membrane protein Sporozoite_P67 PF05642.6 EGD93303.1 - 0.036 11.9 3.9 0.044 11.6 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.6 EGD93303.1 - 3.2 5.7 9.9 4.5 5.2 6.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Malate_synthase PF01274.17 EGD93304.1 - 7.8e-231 766.6 0.0 8.8e-231 766.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase PsbH PF00737.15 EGD93305.1 - 0.033 13.7 1.6 0.034 13.7 0.1 1.8 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Pyr_redox_3 PF13738.1 EGD93306.1 - 1.1e-18 68.0 0.0 3.4e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGD93306.1 - 1.1e-11 43.6 0.0 4.8e-08 31.6 0.1 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGD93306.1 - 2.5e-10 40.2 0.1 1e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD93306.1 - 0.00014 20.9 0.0 0.44 9.3 0.0 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGD93306.1 - 0.0023 17.6 0.1 0.059 13.1 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EGD93306.1 - 0.021 13.7 0.3 0.58 9.0 0.1 3.0 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EGD93306.1 - 0.08 13.3 0.6 1.6 9.1 0.0 3.1 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD93306.1 - 0.23 9.8 0.6 0.39 9.1 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_3 PF00933.16 EGD93307.1 - 4.7e-84 281.8 0.0 6.4e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGD93307.1 - 7.6e-42 143.3 0.4 1.4e-40 139.2 0.3 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGD93307.1 - 8.3e-22 76.9 0.1 1.9e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC2_membrane_4 PF12730.2 EGD93307.1 - 0.043 12.9 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2393 PF09624.5 EGD93307.1 - 0.18 11.3 0.3 9.1 5.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Serpin PF00079.15 EGD93308.1 - 4.6e-53 180.6 0.0 5.6e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) AA_permease_2 PF13520.1 EGD93309.1 - 5.1e-51 173.5 55.6 5.9e-51 173.3 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD93309.1 - 1.5e-20 72.9 41.8 2.1e-20 72.5 28.9 1.1 1 0 0 1 1 1 1 Amino acid permease GST_N_2 PF13409.1 EGD93311.1 - 9.8e-11 41.4 0.0 2.4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGD93311.1 - 7.6e-10 38.8 0.0 1.8e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD93311.1 - 1e-05 25.3 0.2 5.7e-05 22.9 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGD93311.1 - 0.0042 17.0 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD93311.1 - 0.021 15.2 0.0 0.049 14.1 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.22 EGD93312.1 - 3.5e-44 150.4 0.1 1.9e-24 86.5 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGD93312.1 - 2.6e-15 57.1 0.0 0.0073 16.3 0.0 4.3 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EGD93312.1 - 8.8e-11 41.4 0.2 0.0013 17.9 0.0 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EGD93312.1 - 9.7e-07 28.3 0.1 2.1e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.18 EGD93312.1 - 1.7e-06 27.9 0.1 0.047 13.6 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EGD93312.1 - 2.5e-06 26.8 1.8 0.04 13.4 0.6 2.8 2 1 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EGD93312.1 - 2.6e-06 26.7 0.0 0.02 14.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EGD93312.1 - 3.6e-06 26.2 0.0 0.12 11.3 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 EGD93312.1 - 1.1e-05 25.8 1.0 0.02 15.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EGD93312.1 - 2.3e-05 24.2 0.0 0.41 10.5 0.0 3.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EGD93312.1 - 3.8e-05 24.4 0.1 0.1 13.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 EGD93312.1 - 4e-05 24.0 0.2 0.029 14.8 0.0 3.1 3 0 0 3 3 2 1 Miro-like protein NACHT PF05729.7 EGD93312.1 - 0.00012 21.7 1.5 0.046 13.3 0.0 2.9 3 0 0 3 3 2 1 NACHT domain AAA_10 PF12846.2 EGD93312.1 - 0.00013 21.4 4.5 0.3 10.5 0.2 4.2 4 1 0 4 4 4 2 AAA-like domain AAA_22 PF13401.1 EGD93312.1 - 0.00025 21.1 0.1 1.6 8.8 0.0 3.5 3 1 0 3 3 2 2 AAA domain DUF87 PF01935.12 EGD93312.1 - 0.00031 20.6 1.1 0.057 13.2 0.1 3.4 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 EGD93312.1 - 0.0014 18.0 0.0 0.47 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGD93312.1 - 0.0017 18.3 0.2 0.016 15.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EGD93312.1 - 0.0039 17.3 0.2 4.1 7.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase HEAT PF02985.17 EGD93312.1 - 0.0066 16.4 0.2 66 3.9 0.2 5.1 5 0 0 5 5 5 0 HEAT repeat MobB PF03205.9 EGD93312.1 - 0.012 15.2 0.1 5.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EGD93312.1 - 0.034 13.6 0.0 9.3 5.6 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ArgK PF03308.11 EGD93312.1 - 0.036 12.8 0.3 6 5.5 0.1 2.4 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 EGD93312.1 - 0.046 14.0 0.2 2.2 8.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.1 EGD93312.1 - 0.049 13.5 0.0 17 5.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain DUF1666 PF07891.7 EGD93312.1 - 0.061 12.7 0.1 0.48 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1666) PduV-EutP PF10662.4 EGD93312.1 - 0.087 12.3 0.1 0.96 8.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HEAT_2 PF13646.1 EGD93312.1 - 0.16 12.2 3.2 2.5 8.4 0.0 3.5 2 2 1 3 3 3 0 HEAT repeats DUF3584 PF12128.3 EGD93312.1 - 0.43 7.8 2.3 0.82 6.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Glyco_hydro_92 PF07971.7 EGD93313.1 - 1.4e-169 565.0 0.3 1.8e-169 564.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Citrate_synt PF00285.16 EGD93314.1 - 2.5e-101 338.9 0.0 2.9e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase ICL PF00463.16 EGD93315.1 - 1.3e-196 653.8 0.0 1.5e-196 653.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EGD93315.1 - 1.2e-11 44.3 0.0 2.9e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase AMP-binding PF00501.23 EGD93316.1 - 2.6e-70 236.9 0.0 3.2e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD93316.1 - 2.5e-10 41.1 0.1 6.4e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1661 PF07877.6 EGD93316.1 - 0.11 12.0 0.4 0.28 10.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) MmgE_PrpD PF03972.9 EGD93317.1 - 8.4e-150 498.8 0.0 9.6e-150 498.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DNA_methylase PF00145.12 EGD93318.1 - 4.2e-43 147.7 0.0 7.7e-33 114.0 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase GATase_2 PF00310.16 EGD93319.1 - 7.5e-20 70.9 0.0 1.5e-15 56.7 0.0 2.7 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGD93319.1 - 9e-15 54.8 0.0 1.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EGD93319.1 - 3e-13 49.5 0.0 7.8e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EGD93319.1 - 6.6e-12 45.2 0.2 1.7e-11 43.9 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EGD93319.1 - 5.4e-06 25.2 0.0 9.9e-06 24.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II HhH-GPD PF00730.20 EGD93320.1 - 6.1e-10 39.3 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Aldedh PF00171.17 EGD93321.1 - 2.7e-123 411.7 0.0 3.3e-123 411.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2992 PF11208.3 EGD93322.1 - 0.0082 16.0 3.3 0.0082 16.0 2.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2992) Pkinase PF00069.20 EGD93323.1 - 2.7e-30 105.3 0.0 4.3e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93323.1 - 2.9e-18 65.8 0.0 4.3e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD93323.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGD93323.1 - 0.0074 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGD93323.1 - 0.011 14.8 0.1 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGD93323.1 - 0.087 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL F-box-like_2 PF13013.1 EGD93324.1 - 0.0088 15.7 0.3 0.026 14.2 0.2 1.9 1 1 0 1 1 1 1 F-box-like domain F-box-like PF12937.2 EGD93324.1 - 0.08 12.6 0.5 0.19 11.4 0.3 1.6 1 0 0 1 1 1 0 F-box-like Mt_ATP-synt_D PF05873.7 EGD93326.1 - 4.9e-18 65.2 2.3 6e-18 64.9 1.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T2SM_b PF10741.4 EGD93326.1 - 0.0087 15.6 0.5 0.049 13.2 0.0 2.1 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein M subtype b EzrA PF06160.7 EGD93326.1 - 0.0095 14.1 2.2 0.016 13.4 1.4 1.4 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Flagellin_N PF00669.15 EGD93326.1 - 0.16 11.7 1.9 3.8 7.3 0.2 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region FlaC_arch PF05377.6 EGD93326.1 - 0.18 11.6 0.8 52 3.8 0.0 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 EGD93326.1 - 0.73 9.6 6.7 2.8 7.8 1.3 2.5 1 1 0 2 2 2 0 Tropomyosin like NAC PF01849.13 EGD93327.1 - 4.5e-24 83.7 0.0 5.5e-23 80.2 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EGD93327.1 - 0.00019 21.1 0.5 0.00037 20.2 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain SpoIIIAH PF12685.2 EGD93327.1 - 0.41 10.1 11.2 0.16 11.4 5.7 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein CENP-B_dimeris PF09026.5 EGD93327.1 - 0.69 10.1 5.6 11 6.3 2.6 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ribosomal_L14e PF01929.12 EGD93328.1 - 6.2e-27 93.7 2.1 8.7e-27 93.2 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EGD93328.1 - 6.6e-07 28.8 1.1 1.2e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 KOW motif MFS_1 PF07690.11 EGD93329.1 - 1.5e-33 116.0 26.7 4.6e-21 74.9 8.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD93329.1 - 6.8e-11 41.4 13.6 2.1e-10 39.7 3.1 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EGD93329.1 - 1.4e-10 40.1 0.0 9.4e-05 20.9 1.0 3.7 1 1 3 4 4 4 4 MFS/sugar transport protein MFS_1_like PF12832.2 EGD93329.1 - 0.00044 19.9 2.5 0.068 12.9 0.1 3.2 3 0 0 3 3 3 2 MFS_1 like family Folate_carrier PF01770.13 EGD93329.1 - 0.00072 18.1 0.0 0.0013 17.3 0.0 1.3 1 0 0 1 1 1 1 Reduced folate carrier MFS_3 PF05977.8 EGD93329.1 - 0.8 7.7 5.7 0.41 8.7 0.3 2.8 2 2 2 4 4 4 0 Transmembrane secretion effector SRP-alpha_N PF04086.8 EGD93330.1 - 1.3e-74 251.1 0.0 1.8e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EGD93330.1 - 1.4e-50 171.5 0.0 2.4e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 EGD93330.1 - 1.6e-06 27.6 0.1 3.7e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 EGD93330.1 - 3.3e-06 27.1 2.1 4.4e-06 26.6 0.1 2.3 2 1 0 2 2 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EGD93330.1 - 5.2e-06 25.4 0.0 1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EGD93330.1 - 0.0006 19.8 0.3 0.0032 17.4 0.0 2.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 EGD93330.1 - 0.0014 18.2 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EGD93330.1 - 0.0045 16.6 0.1 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EGD93330.1 - 0.014 15.3 0.0 0.11 12.4 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase Fer4_NifH PF00142.13 EGD93330.1 - 0.044 12.9 0.0 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.1 EGD93330.1 - 0.12 12.4 0.0 0.78 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain YIF1 PF03878.10 EGD93331.1 - 2.6e-73 246.1 4.4 3.2e-73 245.8 3.0 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EGD93331.1 - 0.00063 19.2 5.7 0.00063 19.2 3.9 1.5 2 0 0 2 2 2 1 Yip1 domain Catalase PF00199.14 EGD93332.1 - 1e-164 547.7 0.8 1.3e-164 547.4 0.5 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGD93332.1 - 1e-16 60.5 0.0 1.9e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EGD93332.1 - 0.0043 16.5 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family F-box-like PF12937.2 EGD93333.1 - 0.065 12.9 0.3 0.31 10.8 0.0 2.3 2 0 0 2 2 2 0 F-box-like RabGAP-TBC PF00566.13 EGD93335.1 - 3.9e-38 131.0 1.4 7.3e-38 130.1 1.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EGD93335.1 - 5.7e-11 42.1 0.0 0.00019 20.7 0.0 3.6 3 1 0 4 4 4 3 Domain of unknown function (DUF3548) DUF2360 PF10152.4 EGD93335.1 - 1.9 8.7 5.6 0.58 10.4 1.2 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) GAS2 PF02187.12 EGD93336.1 - 0.00018 21.2 0.1 0.00037 20.2 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hus1 PF04005.7 EGD93337.1 - 2.4e-109 364.7 0.0 2.7e-109 364.6 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.2 EGD93338.1 - 2.3e-104 349.1 0.1 3.3e-104 348.6 0.1 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 EGD93338.1 - 2.5e-39 135.6 23.3 2.5e-39 135.6 16.2 4.0 3 0 0 3 3 3 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 EGD93338.1 - 9e-31 106.2 0.0 2.4e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region TPR_19 PF14559.1 EGD93338.1 - 0.27 11.6 3.9 15 5.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GIY-YIG PF01541.19 EGD93339.1 - 0.0021 18.3 0.1 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain E1-E2_ATPase PF00122.15 EGD93340.1 - 3.7e-17 62.1 0.0 9.1e-17 60.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGD93340.1 - 6.5e-14 52.8 0.0 2.2e-13 51.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGD93340.1 - 8.8e-11 42.3 0.0 1.9e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD93340.1 - 6.6e-08 32.4 0.0 5.9e-07 29.3 0.0 2.6 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGD93340.1 - 0.0076 15.8 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mso1_Sec1_bdg PF14475.1 EGD93341.1 - 9.1e-08 31.3 0.0 1.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Sporozoite_P67 PF05642.6 EGD93341.1 - 1.2 6.9 6.4 1.6 6.4 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L28e PF01778.12 EGD93342.1 - 4.2e-32 110.9 0.7 7.9e-32 110.1 0.5 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EGD93342.1 - 9.1e-24 83.4 14.4 9.1e-24 83.4 10.0 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 EGD93342.1 - 0.0001 21.5 13.1 0.00013 21.1 9.1 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 EGD93342.1 - 0.05 11.5 28.4 0.066 11.1 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 EGD93342.1 - 0.076 11.3 24.7 0.089 11.1 17.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_L24e PF01246.15 EGD93342.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L24e PYC_OADA PF02436.13 EGD93342.1 - 0.14 11.5 0.6 0.34 10.2 0.2 1.7 1 1 1 2 2 2 0 Conserved carboxylase domain CENP-T PF15511.1 EGD93342.1 - 0.27 10.4 14.3 0.37 9.9 9.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T zf-C2H2 PF00096.21 EGD93343.1 - 0.00013 22.1 31.7 1.8 9.0 2.9 5.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD93343.1 - 0.056 13.8 35.1 0.22 11.9 0.4 6.2 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGD93343.1 - 0.16 12.0 18.4 0.81 9.8 3.1 3.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-DNA_Pol PF08996.5 EGD93343.1 - 0.43 9.9 5.5 5.8 6.2 0.1 2.9 1 1 2 3 3 3 0 DNA Polymerase alpha zinc finger Stc1 PF12898.2 EGD93343.1 - 4.5 7.3 7.6 0.12 12.4 0.5 2.0 2 0 0 2 2 2 0 Stc1 domain ECH PF00378.15 EGD93344.1 - 1.6e-24 86.3 0.0 2.1e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family D123 PF07065.9 EGD93345.1 - 1.2e-91 306.9 0.0 3.3e-91 305.4 0.0 1.7 1 1 0 1 1 1 1 D123 Vps51 PF08700.6 EGD93346.1 - 1.1e-13 50.8 0.0 7.7e-13 48.1 0.0 2.6 2 0 0 2 2 2 1 Vps51/Vps67 DUF1640 PF07798.6 EGD93347.1 - 1.3e-10 41.6 7.9 3.3e-10 40.2 5.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) ALMT PF11744.3 EGD93347.1 - 0.014 14.0 2.2 0.02 13.5 1.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Baculo_PEP_C PF04513.7 EGD93347.1 - 0.7 9.7 5.9 1.3 8.8 4.1 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HEAT_2 PF13646.1 EGD93348.1 - 2.5e-11 43.6 2.4 0.0081 16.4 0.0 7.4 7 1 1 8 8 8 5 HEAT repeats HEAT PF02985.17 EGD93348.1 - 6.4e-10 38.2 8.1 1.1 9.4 0.0 9.8 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EGD93348.1 - 0.00078 19.7 0.0 0.084 13.2 0.0 3.8 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 EGD93348.1 - 0.011 15.5 1.4 6.8 6.6 0.0 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Chalcone PF02431.10 EGD93348.1 - 0.066 12.6 0.1 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Chalcone-flavanone isomerase Transcrip_reg PF01709.15 EGD93349.1 - 9.8e-63 211.4 0.1 1.1e-62 211.2 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator CENP-I PF07778.6 EGD93350.1 - 7.4e-93 311.4 2.8 1e-92 310.9 1.9 1.1 1 0 0 1 1 1 1 Mis6 Sedlin_N PF04628.8 EGD93350.1 - 0.037 13.8 0.0 0.56 10.0 0.0 2.5 2 0 0 2 2 2 0 Sedlin, N-terminal conserved region DUF4360 PF14273.1 EGD93351.1 - 1.2e-63 214.0 1.7 1.5e-63 213.8 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CLPTM1 PF05602.7 EGD93353.1 - 1.9e-125 419.0 1.3 5.1e-95 318.7 0.0 2.1 1 1 1 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1240 PF06836.7 EGD93353.1 - 0.31 11.2 2.6 0.75 10.0 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) adh_short PF00106.20 EGD93354.1 - 1.9e-09 37.6 0.0 6.3e-09 35.9 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGD93354.1 - 0.0023 17.6 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 KR domain ASXH PF13919.1 EGD93355.1 - 3.5e-43 146.7 1.3 7e-43 145.7 0.9 1.5 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.1 EGD93356.1 - 8.8e-28 95.6 1.0 1.6e-27 94.8 0.7 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EGD93356.1 - 4.8e-16 58.1 0.7 1.6e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 Synaptobrevin DUF3510 PF12022.3 EGD93356.1 - 0.013 15.5 2.1 0.24 11.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Bac_small_YrzI PF09501.5 EGD93356.1 - 0.029 14.2 0.8 0.064 13.1 0.6 1.6 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) PilJ PF13675.1 EGD93356.1 - 0.08 13.2 2.6 0.48 10.7 0.2 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.7 EGD93356.1 - 0.12 12.1 1.6 0.26 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) E1-E2_ATPase PF00122.15 EGD93356.1 - 1.5 7.7 4.7 2.8 6.9 0.1 2.5 2 1 1 3 3 3 0 E1-E2 ATPase EMP24_GP25L PF01105.19 EGD93356.1 - 4.4 6.9 7.2 21 4.7 3.6 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Elong_Iki1 PF10483.4 EGD93357.1 - 1.2e-83 280.7 0.0 5.2e-83 278.6 0.0 1.7 1 1 0 1 1 1 1 Elongator subunit Iki1 DUF1777 PF08648.7 EGD93358.1 - 4e-26 91.8 35.7 4e-26 91.8 24.7 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF1777) DAO PF01266.19 EGD93359.1 - 1.1e-63 215.2 0.6 1.4e-63 214.9 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD93359.1 - 1.6e-07 31.2 0.1 5.3e-07 29.5 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGD93359.1 - 4.1e-06 26.8 0.3 0.026 14.3 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGD93359.1 - 0.0002 20.3 0.4 0.0032 16.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 EGD93359.1 - 0.0014 17.3 0.1 0.1 11.2 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 EGD93359.1 - 0.003 17.9 0.1 0.015 15.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD93359.1 - 0.0054 15.8 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EGD93359.1 - 0.0082 15.0 0.1 0.95 8.2 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EGD93359.1 - 0.016 14.9 0.3 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Strep_67kDa_ant PF06100.6 EGD93359.1 - 0.04 12.2 0.1 0.056 11.7 0.1 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Pyr_redox_3 PF13738.1 EGD93359.1 - 0.052 13.5 0.0 8.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD93359.1 - 0.13 11.3 3.0 1.1 8.2 2.1 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Glyco_hydro_63 PF03200.11 EGD93360.1 - 4.1e-247 822.0 0.0 3.8e-246 818.8 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EGD93360.1 - 0.00032 19.4 0.8 0.00065 18.4 0.6 1.5 1 1 0 1 1 1 1 Trehalase MMtag PF10159.4 EGD93361.1 - 2.1e-32 110.9 4.5 2.1e-32 110.9 3.1 2.6 2 1 0 2 2 2 1 Kinase phosphorylation protein CRT10 PF08728.5 EGD93362.1 - 3.9e-16 58.2 0.1 1.4e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 CRT10 Daxx PF03344.10 EGD93362.1 - 0.65 8.4 14.6 0.94 7.8 10.1 1.1 1 0 0 1 1 1 0 Daxx Family DUF3402 PF11882.3 EGD93363.1 - 3.3e-141 471.0 0.0 4.4e-141 470.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EGD93363.1 - 1.2e-82 277.1 0.0 1.6e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein RWD PF05773.17 EGD93364.1 - 2.6e-20 72.4 0.1 4.7e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EGD93364.1 - 9.4e-17 60.6 41.3 4.2e-14 52.1 2.4 4.0 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EGD93364.1 - 0.0064 16.2 10.8 0.0064 16.2 7.5 3.6 2 1 1 3 3 3 2 Ring finger domain PAP2 PF01569.16 EGD93365.1 - 6.1e-18 64.7 1.0 1.2e-17 63.8 0.7 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 EGD93365.1 - 0.021 14.5 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family Ldh_2 PF02615.9 EGD93366.1 - 1.4e-103 346.1 0.0 1.6e-103 346.0 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DUF2346 PF09803.4 EGD93367.1 - 9.6e-06 25.3 0.1 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) DUF3317 PF11779.3 EGD93368.1 - 4.5e-21 74.0 4.9 5.7e-21 73.7 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) RF-1 PF00472.15 EGD93369.1 - 7.4e-26 90.1 6.2 1.1e-25 89.6 4.3 1.1 1 0 0 1 1 1 1 RF-1 domain CFTR_R PF14396.1 EGD93369.1 - 0.048 13.0 2.3 0.07 12.4 1.6 1.2 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain CAS_CSE1 PF03378.10 EGD93370.1 - 6.5e-158 525.5 0.0 1.6e-157 524.3 0.0 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EGD93370.1 - 1.6e-154 513.9 3.7 2.4e-154 513.4 2.6 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EGD93370.1 - 4e-15 55.4 0.2 2.1e-14 53.2 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EGD93370.1 - 0.019 14.8 1.7 1.7 8.5 0.0 4.2 3 1 0 3 3 3 0 Exportin 1-like protein DUF3384 PF11864.3 EGD93371.1 - 8.8e-82 275.0 0.0 1.7e-81 274.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Tuberin PF03542.11 EGD93371.1 - 8.3e-30 104.0 0.9 4.3e-28 98.4 0.0 2.9 3 0 0 3 3 3 1 Tuberin PUF PF00806.14 EGD93372.1 - 6.6e-43 141.8 4.0 7.5e-07 28.2 0.0 6.7 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat PepSY_TM_2 PF13703.1 EGD93374.1 - 0.072 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix Sarcoglycan_2 PF05510.8 EGD93374.1 - 0.1 10.8 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Phosphodiest PF01663.17 EGD93375.1 - 1.1e-16 61.0 0.5 1.8e-16 60.4 0.3 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EGD93375.1 - 8.8e-06 25.2 1.4 1.5e-05 24.5 1.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EGD93375.1 - 0.0003 20.0 0.0 0.0005 19.3 0.0 1.4 1 0 0 1 1 1 1 Sulfatase cwf21 PF08312.7 EGD93376.1 - 1.1e-06 28.4 19.7 1.1e-06 28.4 13.6 2.6 2 1 0 2 2 2 1 cwf21 domain DUF1875 PF08961.5 EGD93376.1 - 0.79 8.9 7.4 0.14 11.4 2.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1875) DUF904 PF06005.7 EGD93376.1 - 0.81 10.0 9.7 0.3 11.4 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) CDC37_N PF03234.9 EGD93376.1 - 1.1 9.5 9.5 0.14 12.4 2.0 1.9 1 1 0 2 2 2 0 Cdc37 N terminal kinase binding DUF972 PF06156.8 EGD93376.1 - 1.5 9.1 6.0 0.56 10.5 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) HA2 PF04408.18 EGD93377.1 - 1.2e-18 66.9 0.1 1.2e-18 66.9 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGD93377.1 - 1.2e-14 53.9 0.0 4.5e-14 52.0 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EGD93377.1 - 4.2e-12 45.9 0.0 1.1e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EGD93377.1 - 2.5e-10 40.1 0.0 3.7e-08 33.0 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGD93377.1 - 0.0035 17.4 0.3 0.021 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EGD93377.1 - 0.0096 15.7 10.0 0.25 11.1 0.0 3.7 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit T2SE PF00437.15 EGD93377.1 - 0.045 12.6 0.0 0.11 11.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EGD93377.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2372 PF10178.4 EGD93378.1 - 0.0002 21.4 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) Cohesin_load PF10345.4 EGD93381.1 - 1.5e-161 538.6 4.4 1.9e-161 538.3 3.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor Lactamase_B_4 PF13691.1 EGD93381.1 - 0.03 13.8 0.0 0.085 12.3 0.0 1.7 1 0 0 1 1 1 0 tRNase Z endonuclease NTR2 PF15458.1 EGD93381.1 - 0.066 12.4 0.4 0.15 11.2 0.3 1.5 1 0 0 1 1 1 0 Nineteen complex-related protein 2 DUF3663 PF12404.3 EGD93381.1 - 0.27 11.0 3.0 14 5.5 0.3 2.5 2 0 0 2 2 2 0 Peptidase TPR_4 PF07721.9 EGD93381.1 - 0.43 11.1 4.4 16 6.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Histone PF00125.19 EGD93382.1 - 2.8e-28 97.8 0.1 4.1e-28 97.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGD93382.1 - 0.00028 20.9 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGD93382.1 - 0.0084 16.1 0.3 0.017 15.1 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGD93382.1 - 0.024 13.8 0.8 0.034 13.4 0.6 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T DER1 PF04511.10 EGD93383.1 - 1.2e-48 165.2 4.4 1.4e-48 165.0 3.0 1.0 1 0 0 1 1 1 1 Der1-like family Serpentine_r_xa PF03383.10 EGD93383.1 - 0.056 13.1 1.8 0.099 12.4 1.3 1.4 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa EMP70 PF02990.11 EGD93384.1 - 9.5e-119 397.1 13.0 7.8e-63 212.7 17.0 3.0 1 1 1 2 2 2 2 Endomembrane protein 70 ubiquitin PF00240.18 EGD93385.1 - 1.6e-17 62.6 0.0 2.8e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EGD93385.1 - 1.6e-09 37.2 0.0 5.4e-09 35.6 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EGD93385.1 - 1.3e-06 27.9 0.0 2.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGD93385.1 - 0.00013 22.0 0.0 0.00056 20.0 0.0 1.9 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGD93385.1 - 0.0013 18.6 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CPSF_A PF03178.10 EGD93386.1 - 3.2e-102 341.9 0.0 2.8e-100 335.5 0.0 3.0 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EGD93386.1 - 7e-49 166.3 0.0 1e-47 162.4 0.0 2.2 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 EGD93386.1 - 0.81 9.6 2.4 0.84 9.6 0.1 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat CN_hydrolase PF00795.17 EGD93387.1 - 1.2e-21 76.9 0.0 1.6e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BP28CT PF08146.7 EGD93388.1 - 4.5e-43 146.6 2.3 1e-42 145.4 0.2 2.8 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EGD93388.1 - 9.1e-28 96.6 18.5 6.7e-27 93.8 0.6 6.6 8 0 0 8 8 8 2 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EGD93388.1 - 1.2e-07 31.8 9.6 0.13 12.5 0.0 7.2 5 1 1 6 6 6 3 HEAT repeats HEAT PF02985.17 EGD93388.1 - 0.21 11.7 13.7 1.3 9.2 0.0 7.5 9 0 0 9 9 9 0 HEAT repeat HEAT_EZ PF13513.1 EGD93388.1 - 1.4 9.5 17.5 2.7 8.6 0.0 7.2 8 1 0 8 8 8 0 HEAT-like repeat NRDE-2 PF08424.5 EGD93389.1 - 7.1e-87 291.2 0.0 6.5e-86 288.1 0.0 2.5 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EGD93389.1 - 0.00096 19.5 1.1 55 4.8 0.0 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGD93389.1 - 0.0036 17.9 0.0 0.13 13.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat UDG PF03167.14 EGD93390.1 - 6.6e-19 67.8 0.0 1.6e-18 66.5 0.0 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily CitMHS PF03600.11 EGD93391.1 - 0.078 11.5 0.4 0.12 10.9 0.3 1.3 1 0 0 1 1 1 0 Citrate transporter 7TMR-DISM_7TM PF07695.6 EGD93391.1 - 0.5 9.9 9.1 1.6 8.3 6.3 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling NAD_binding_6 PF08030.7 EGD93393.1 - 1e-23 83.9 0.0 1.7e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGD93393.1 - 4.7e-23 81.0 0.0 1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGD93393.1 - 8.4e-18 64.6 9.2 1.7e-17 63.6 6.4 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGD93393.1 - 4.9e-05 23.3 0.0 0.00013 22.0 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGD93393.1 - 0.0093 16.5 0.0 3.7 8.1 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain SBDS PF01172.13 EGD93394.1 - 4.6e-28 96.8 0.2 5.3e-28 96.6 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 EGD93394.1 - 0.043 13.5 0.0 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Phage XkdN-like protein RhoGEF PF00621.15 EGD93395.1 - 3.9e-23 82.2 0.0 8.4e-23 81.1 0.0 1.6 1 1 0 1 1 1 1 RhoGEF domain PDZ_2 PF13180.1 EGD93396.1 - 2e-05 24.3 0.0 4.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EGD93396.1 - 0.0028 17.7 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Ras PF00071.17 EGD93397.1 - 1.5e-49 167.5 0.0 1.8e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD93397.1 - 9.4e-16 58.3 0.0 2e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGD93397.1 - 3.5e-11 42.6 0.0 5.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EGD93397.1 - 0.00025 21.1 0.1 0.0014 18.7 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EGD93397.1 - 0.00044 19.4 0.0 0.00055 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EGD93397.1 - 0.0054 15.4 1.2 0.96 8.0 0.1 2.9 2 1 1 3 3 3 1 G-protein alpha subunit Pox_A32 PF04665.7 EGD93397.1 - 0.029 13.6 0.1 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EGD93397.1 - 0.059 13.5 0.1 0.16 12.1 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EGD93397.1 - 0.079 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EGD93397.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit UPF0079 PF02367.12 EGD93397.1 - 0.15 11.7 0.1 0.37 10.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SNF2_N PF00176.18 EGD93398.1 - 4.2e-69 232.6 0.5 7.3e-69 231.8 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD93398.1 - 8.6e-11 41.5 0.0 2.5e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EGD93398.1 - 6.7e-09 35.2 3.2 1.1e-08 34.5 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD93398.1 - 5.6e-07 29.4 4.7 1.1e-06 28.5 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD93398.1 - 3.1e-06 26.7 3.5 6.5e-06 25.7 2.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EGD93398.1 - 3.4e-06 26.6 0.0 1.1e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 EGD93398.1 - 4e-06 26.5 3.6 7.6e-06 25.6 2.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGD93398.1 - 3.6e-05 23.3 3.6 7.8e-05 22.3 2.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGD93398.1 - 0.0015 18.0 3.1 0.0035 16.8 2.2 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGD93398.1 - 0.0021 17.8 5.5 0.0046 16.8 3.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD93398.1 - 0.0056 16.3 1.1 0.012 15.3 0.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger SPT6_acidic PF14632.1 EGD93398.1 - 0.56 10.4 17.5 0.14 12.3 4.1 2.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 F-box-like PF12937.2 EGD93399.1 - 0.00065 19.3 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EGD93399.1 - 0.1 12.2 1.8 3 7.6 0.0 2.5 2 0 0 2 2 2 0 F-box domain Ran_BP1 PF00638.13 EGD93400.1 - 5.4e-14 52.2 0.0 1.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 EGD93400.1 - 3.5e-05 24.0 77.1 0.00034 20.7 26.1 10.2 3 3 5 8 8 8 4 Nucleoporin FG repeat region WH1 PF00568.18 EGD93400.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 WH1 domain NOA36 PF06524.7 EGD93400.1 - 3.9 6.6 10.4 7.4 5.7 7.2 1.4 1 0 0 1 1 1 0 NOA36 protein CN_hydrolase PF00795.17 EGD93401.1 - 1.1e-31 109.6 0.0 1.6e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L31e PF01198.14 EGD93401.1 - 2.2e-30 104.1 0.6 4.3e-30 103.2 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L31e Fungal_trans PF04082.13 EGD93402.1 - 1.4e-10 40.5 3.3 2.3e-10 39.7 2.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD93402.1 - 3e-06 27.0 8.0 5.5e-06 26.1 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF885 PF05960.6 EGD93402.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) FAD_binding_3 PF01494.14 EGD93403.1 - 8.4e-32 110.5 0.1 1.1e-31 110.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EGD93403.1 - 5.3e-08 31.9 1.4 2.2e-05 23.3 0.1 2.4 1 1 1 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 EGD93403.1 - 2.9e-05 23.1 0.0 5.5e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EGD93403.1 - 3e-05 24.1 0.0 5.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD93403.1 - 0.0002 20.4 0.7 0.12 11.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD93403.1 - 0.003 17.5 0.6 0.0092 15.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGD93403.1 - 0.0051 17.1 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD93403.1 - 0.041 13.7 0.6 0.098 12.5 0.4 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thioesterase PF00975.15 EGD93404.1 - 1.3e-19 71.3 0.0 1.6e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EGD93404.1 - 1.2e-07 31.8 0.0 1.3e-07 31.7 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD93404.1 - 5.8e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD93404.1 - 0.0015 18.1 0.0 0.0029 17.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pyr_redox PF00070.22 EGD93404.1 - 0.026 14.9 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PGAP1 PF07819.8 EGD93404.1 - 0.057 12.9 0.4 0.86 9.1 0.0 2.1 1 1 0 2 2 2 0 PGAP1-like protein Asp PF00026.18 EGD93405.1 - 2.7e-12 46.5 0.3 5e-11 42.4 0.2 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGD93405.1 - 0.0023 17.4 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal p450 PF00067.17 EGD93406.1 - 2.8e-51 174.4 0.0 4.6e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2953 PF11167.3 EGD93406.1 - 0.1 12.4 0.1 0.31 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) AMP-binding PF00501.23 EGD93407.1 - 1.6e-84 283.6 0.0 2.7e-84 282.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EGD93407.1 - 5.7e-73 245.5 0.0 1.2e-72 244.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGD93407.1 - 2.8e-64 217.4 0.0 4.6e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGD93407.1 - 7.6e-59 198.4 0.0 4.2e-58 195.9 0.0 2.4 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EGD93407.1 - 7.6e-56 189.4 0.0 1.3e-55 188.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EGD93407.1 - 3.5e-53 180.4 0.0 5.8e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 EGD93407.1 - 2.5e-48 164.1 0.9 5.9e-48 162.9 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGD93407.1 - 1.6e-40 137.6 0.2 1e-39 135.0 0.1 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EGD93407.1 - 2.3e-36 125.0 0.0 6.7e-36 123.4 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein ADH_zinc_N PF00107.21 EGD93407.1 - 7.2e-21 74.0 0.0 2.1e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EGD93407.1 - 9.3e-21 73.8 0.3 8.7e-11 41.9 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EGD93407.1 - 2.7e-11 43.6 0.0 8.8e-11 41.9 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain ADH_zinc_N_2 PF13602.1 EGD93407.1 - 2.2e-10 41.5 0.0 4.8e-09 37.1 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EGD93407.1 - 0.0068 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF1233 PF06806.7 EGD93407.1 - 0.16 11.5 0.0 0.4 10.2 0.0 1.6 1 0 0 1 1 1 0 Putative excisionase (DUF1233) GP120 PF00516.13 EGD93407.1 - 5.5 5.0 0.0 9.6 4.2 0.0 1.2 1 0 0 1 1 1 0 Envelope glycoprotein GP120 ATG2_CAD PF13329.1 EGD93411.1 - 8.4e-48 161.8 0.1 1.9e-47 160.7 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EGD93411.1 - 1.2e-22 79.9 0.2 2.9e-22 78.6 0.1 1.7 1 0 0 1 1 1 1 ATG C terminal domain A_deaminase PF00962.17 EGD93412.1 - 5.8e-38 130.6 0.0 5.2e-37 127.4 0.0 2.3 2 1 0 2 2 2 1 Adenosine/AMP deaminase Ribosomal_S17 PF00366.15 EGD93413.1 - 0.0032 17.4 0.5 0.0055 16.7 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 PNPOx_C PF10590.4 EGD93413.1 - 0.14 11.7 0.2 0.27 10.7 0.2 1.5 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region AAA PF00004.24 EGD93414.1 - 7.8e-37 126.4 0.0 1.3e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EGD93414.1 - 4.5e-10 39.2 0.1 9.4e-06 25.4 0.0 3.0 3 0 0 3 3 2 2 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EGD93414.1 - 1.7e-05 24.9 0.1 0.00015 21.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGD93414.1 - 7.6e-05 22.6 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EGD93414.1 - 0.00013 21.1 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGD93414.1 - 0.00017 21.5 0.2 0.037 14.0 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EGD93414.1 - 0.0021 17.7 0.0 0.0081 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EGD93414.1 - 0.0029 17.0 0.0 0.0067 15.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EGD93414.1 - 0.0034 16.1 0.0 0.0064 15.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EGD93414.1 - 0.0052 15.9 0.1 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EGD93414.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGD93414.1 - 0.023 14.4 0.0 0.023 14.4 0.0 2.1 3 0 0 3 3 1 0 Part of AAA domain AAA_28 PF13521.1 EGD93414.1 - 0.028 14.3 0.0 0.43 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EGD93414.1 - 0.03 13.7 0.2 0.49 9.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EGD93414.1 - 0.03 15.1 0.4 0.1 13.4 0.0 2.1 2 1 0 2 2 1 0 AAA domain DUF815 PF05673.8 EGD93414.1 - 0.033 13.1 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EGD93414.1 - 0.098 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EGD93414.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGD93414.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGD93414.1 - 0.22 10.7 0.0 0.44 9.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Telomere_Sde2 PF13019.1 EGD93415.1 - 8.7e-64 214.0 0.0 2.9e-63 212.3 0.0 1.9 2 0 0 2 2 2 1 Telomere stability and silencing MMR_HSR1 PF01926.18 EGD93415.1 - 8.8e-05 22.4 0.0 0.00042 20.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase S10_plectin PF03501.10 EGD93416.1 - 5e-40 135.2 0.2 6e-40 135.0 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Peptidase_M20 PF01546.23 EGD93417.1 - 1.4e-21 76.9 0.2 1.9e-21 76.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGD93417.1 - 3.7e-06 26.6 0.0 9.1e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EGD93417.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 HIT PF01230.18 EGD93418.1 - 2.4e-22 79.3 0.1 3e-22 78.9 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGD93418.1 - 5e-13 49.3 0.0 7.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGD93418.1 - 0.0038 16.8 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.15 EGD93419.1 - 1.1e-38 132.2 0.0 2.1e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGD93419.1 - 2.5e-15 56.3 0.0 7.6e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGD93419.1 - 1.8e-09 37.6 0.0 3.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF755 PF05501.6 EGD93419.1 - 0.03 14.3 1.4 0.03 14.3 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DASH_Dam1 PF08653.5 EGD93420.1 - 2.9e-29 100.5 1.6 4.2e-29 100.0 1.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF2265 PF10023.4 EGD93420.1 - 0.14 11.2 0.4 0.18 10.8 0.3 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) CytochromB561_N PF09786.4 EGD93420.1 - 0.14 10.5 10.4 0.17 10.3 7.2 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF2139 PF09910.4 EGD93421.1 - 0.14 11.1 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) UCH PF00443.24 EGD93422.1 - 7.1e-63 212.2 0.6 1.1e-62 211.6 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD93422.1 - 3.9e-33 115.1 0.1 5.4e-33 114.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGD93422.1 - 6.6e-05 22.9 0.8 6.6e-05 22.9 0.5 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein APH PF01636.18 EGD93423.1 - 3.1e-08 33.6 0.0 5.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD93423.1 - 0.033 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Abhydrolase_2 PF02230.11 EGD93424.1 - 9.8e-19 67.6 0.0 1.2e-14 54.3 0.0 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGD93424.1 - 2.1e-05 24.3 0.0 2.7e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD93424.1 - 0.00037 20.4 0.1 0.0042 16.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGD93424.1 - 0.0019 17.6 0.0 0.0097 15.3 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EGD93424.1 - 0.09 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Rhomboid PF01694.17 EGD93425.1 - 2e-11 44.0 10.2 2e-11 44.0 7.1 1.5 2 0 0 2 2 2 1 Rhomboid family DUF3464 PF11947.3 EGD93425.1 - 0.15 11.5 0.1 0.38 10.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DER1 PF04511.10 EGD93425.1 - 0.42 10.0 3.7 1.1 8.7 2.5 1.6 1 1 0 1 1 1 0 Der1-like family Ytp1 PF10355.4 EGD93426.1 - 1.3e-112 375.4 7.3 1.3e-112 375.4 5.1 2.0 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EGD93426.1 - 2e-29 101.2 8.1 2e-29 101.2 5.6 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) DUF1440 PF07274.7 EGD93426.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1440) RTA1 PF04479.8 EGD93427.1 - 1.6e-41 142.2 0.1 2.5e-41 141.6 0.1 1.3 1 0 0 1 1 1 1 RTA1 like protein Pex24p PF06398.6 EGD93427.1 - 0.33 9.6 1.5 0.93 8.2 0.9 1.9 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF2157 PF09925.4 EGD93427.1 - 2.1 7.9 6.0 1.3 8.6 0.4 2.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2157) DUF1832 PF08870.6 EGD93428.1 - 0.019 14.6 0.1 1.7 8.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1832) Gaa1 PF04114.9 EGD93429.1 - 3e-98 329.7 5.3 3.7e-98 329.4 3.7 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.22 EGD93430.1 - 2.1e-10 40.8 0.1 4.6e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 PCI domain Methyltransf_31 PF13847.1 EGD93431.1 - 3.3e-14 52.7 0.0 4.4e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD93431.1 - 5.9e-14 52.1 0.0 7.3e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD93431.1 - 3.3e-12 46.7 0.0 7.5e-12 45.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD93431.1 - 3.6e-12 46.8 0.0 6.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD93431.1 - 3.1e-11 43.6 0.0 8.2e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD93431.1 - 1.5e-08 34.9 0.0 2.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD93431.1 - 3.3e-07 29.6 0.0 6.1e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGD93431.1 - 5.2e-05 23.2 0.0 0.00024 21.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGD93431.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EGD93431.1 - 0.029 13.2 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.9 EGD93431.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.10 EGD93431.1 - 0.1 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 EGD93431.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GMC_oxred_N PF00732.14 EGD93432.1 - 3.6e-62 210.1 0.0 5e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGD93432.1 - 3.2e-38 131.2 0.0 4.8e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EGD93432.1 - 1.2e-08 34.2 0.2 0.0001 21.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD93432.1 - 4.3e-07 29.1 0.0 0.0093 14.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EGD93432.1 - 0.00016 21.6 0.0 0.0007 19.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGD93432.1 - 0.0014 17.5 0.1 0.0021 17.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EGD93432.1 - 0.018 15.4 0.1 5.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD93432.1 - 0.059 12.4 0.1 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EGD93432.1 - 0.13 10.7 0.0 1.1 7.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_10 PF13460.1 EGD93435.1 - 7.4e-17 61.9 0.0 1.1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGD93435.1 - 6.3e-15 55.2 0.0 1.5e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD93435.1 - 5.4e-12 45.0 0.0 8.7e-12 44.3 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EGD93435.1 - 3e-11 43.0 0.0 4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EGD93435.1 - 4.8e-06 25.6 0.2 0.00086 18.2 0.1 3.0 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EGD93435.1 - 1.2e-05 24.3 0.0 0.03 13.2 0.0 2.4 2 1 0 2 2 2 2 RmlD substrate binding domain Saccharop_dh PF03435.13 EGD93435.1 - 0.0024 16.9 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EGD93435.1 - 0.0065 16.3 0.0 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase HIM1 PF08732.5 EGD93435.1 - 0.0085 14.6 0.0 0.012 14.0 0.0 1.2 1 0 0 1 1 1 1 HIM1 DDE_Tnp_1_3 PF13612.1 EGD93435.1 - 0.013 15.2 0.0 0.068 12.9 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain KR PF08659.5 EGD93435.1 - 0.061 12.9 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 KR domain fn3 PF00041.16 EGD93437.1 - 0.015 15.4 0.5 0.025 14.7 0.3 1.3 1 0 0 1 1 1 0 Fibronectin type III domain Plasmod_Pvs28 PF06247.6 EGD93437.1 - 0.11 12.0 0.1 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Plasmodium ookinete surface protein Pvs28 Pkinase PF00069.20 EGD93438.1 - 1.4e-25 89.9 0.0 7.3e-25 87.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93438.1 - 1.4e-14 53.7 0.0 4.6e-12 45.5 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase HEM4 PF02602.10 EGD93439.1 - 8.4e-31 106.9 0.0 1.1e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.20 EGD93440.1 - 5.4e-74 248.6 0.0 6.4e-74 248.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93440.1 - 1.1e-31 109.8 0.0 1.4e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD93440.1 - 0.0004 19.4 0.0 0.0015 17.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGD93440.1 - 0.0038 16.2 0.4 0.0065 15.5 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD93440.1 - 0.011 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGD93440.1 - 0.065 12.0 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sec23_trunk PF04811.10 EGD93441.1 - 6.4e-72 241.8 0.0 1.4e-71 240.6 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGD93441.1 - 1.8e-22 78.6 0.0 1.9e-21 75.3 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EGD93441.1 - 6.9e-18 63.9 4.3 1.4e-17 62.9 3.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EGD93441.1 - 6.9e-17 61.7 0.0 1.5e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EGD93441.1 - 3.3e-06 26.6 0.0 6.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Kinesin PF00225.18 EGD93442.1 - 6.5e-80 268.3 0.2 9.3e-80 267.8 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 EGD93442.1 - 0.0076 15.9 0.3 2.7 7.8 0.0 2.9 3 0 0 3 3 3 2 Helix-hairpin-helix motif TPR_12 PF13424.1 EGD93442.1 - 0.012 15.4 0.2 0.45 10.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.11 EGD93443.1 - 2.5e-24 85.6 47.0 7.1e-17 61.1 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGD93443.1 - 1.6e-10 39.9 13.5 1.6e-10 39.9 9.4 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein OapA_N PF08525.6 EGD93443.1 - 0.29 10.9 4.1 1 9.1 2.8 2.1 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif TSC22 PF01166.13 EGD93444.1 - 0.47 10.4 3.4 17 5.4 0.1 2.8 1 1 2 3 3 3 0 TSC-22/dip/bun family bZIP_2 PF07716.10 EGD93444.1 - 5.7 6.8 12.9 0.24 11.2 4.7 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Chromate_transp PF02417.10 EGD93445.1 - 2.2e-58 196.5 31.5 1.8e-32 112.2 7.1 2.4 2 1 0 2 2 2 2 Chromate transporter Peptidase_M43 PF05572.8 EGD93447.1 - 3.1e-15 56.0 0.4 6.3e-15 55.1 0.3 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EGD93447.1 - 2.3e-05 24.5 5.7 4.6e-05 23.5 4.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EGD93447.1 - 9.2e-05 22.0 3.1 0.00037 20.0 0.2 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EGD93447.1 - 0.00019 21.4 2.1 0.00032 20.6 1.5 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EGD93447.1 - 0.0042 17.5 1.8 0.017 15.6 1.3 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EGD93447.1 - 0.0046 16.3 2.5 0.005 16.1 0.2 1.9 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Peptidase_M7 PF02031.11 EGD93447.1 - 0.0096 15.6 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.4 EGD93447.1 - 0.061 12.1 1.1 0.079 11.8 0.1 1.6 2 0 0 2 2 2 0 Peptidase M66 Peptidase_M10 PF00413.19 EGD93447.1 - 0.08 12.6 0.2 0.12 12.1 0.1 1.3 1 1 0 1 1 1 0 Matrixin AIM24 PF01987.12 EGD93448.1 - 1.5e-45 155.2 0.0 1.9e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 EGD93448.1 - 0.025 15.0 0.5 0.086 13.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4402) ABC_membrane PF00664.18 EGD93449.1 - 2.7e-35 122.1 13.6 3.8e-35 121.6 9.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGD93449.1 - 4.7e-34 117.6 0.0 9.4e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGD93449.1 - 2.5e-07 30.9 0.0 0.003 17.5 0.0 2.6 2 1 1 3 3 2 2 AAA domain SMC_N PF02463.14 EGD93449.1 - 1.2e-05 24.7 0.0 0.0022 17.2 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGD93449.1 - 0.00013 22.0 0.0 0.0009 19.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EGD93449.1 - 0.00017 22.3 0.1 0.00049 20.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGD93449.1 - 0.00052 20.1 0.0 0.003 17.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGD93449.1 - 0.0018 18.1 0.0 0.027 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGD93449.1 - 0.0022 18.2 0.0 0.0062 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGD93449.1 - 0.0027 16.9 0.0 0.0058 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGD93449.1 - 0.0031 17.0 0.1 0.01 15.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EGD93449.1 - 0.024 14.1 0.1 0.12 11.7 0.0 2.0 1 1 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 EGD93449.1 - 0.024 14.5 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EGD93449.1 - 0.026 14.4 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EGD93449.1 - 0.027 13.0 0.0 0.24 9.9 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ATP-synt_ab PF00006.20 EGD93449.1 - 0.029 13.8 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 EGD93449.1 - 0.041 14.2 0.6 0.085 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 EGD93449.1 - 0.048 13.8 0.0 0.37 10.9 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGD93449.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGD93449.1 - 0.083 11.9 0.0 0.45 9.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.10 EGD93449.1 - 0.084 11.5 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2847 PF11009.3 EGD93449.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) DUF2013 PF09431.5 EGD93450.1 - 2e-50 170.1 2.5 2e-50 170.1 1.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Glyco_hydro_17 PF00332.13 EGD93451.1 - 2.8e-06 26.6 3.5 1.7e-05 23.9 0.3 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Aminotran_1_2 PF00155.16 EGD93452.1 - 1.6e-34 119.4 0.0 2.1e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II bcl-2I13 PF12201.3 EGD93452.1 - 0.099 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing Zn_clus PF00172.13 EGD93453.1 - 0.007 16.2 1.0 0.007 16.2 0.7 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ApoLp-III PF07464.6 EGD93453.1 - 0.17 11.9 0.6 0.35 10.8 0.2 1.6 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) ATP-grasp_4 PF13535.1 EGD93454.1 - 1.5e-23 83.4 0.0 1.1e-20 74.0 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGD93454.1 - 1.6e-08 34.2 0.0 2.9e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EGD93454.1 - 3.6e-07 29.2 0.0 0.0011 17.7 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EGD93454.1 - 0.0003 20.6 0.0 0.0071 16.2 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGD93454.1 - 0.0098 15.1 0.0 0.033 13.4 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 EGD93454.1 - 0.024 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Glucan_synthase PF02364.10 EGD93455.1 - 0 1460.3 0.0 0 1459.8 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EGD93455.1 - 2.8e-39 133.6 0.2 6.4e-39 132.4 0.2 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Nop53 PF07767.6 EGD93456.1 - 0.17 10.8 16.8 0.19 10.7 11.6 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SLX9 PF15341.1 EGD93456.1 - 0.23 11.8 9.7 0.3 11.5 6.7 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 PRP38_assoc PF12871.2 EGD93456.1 - 0.36 11.3 15.9 0.6 10.6 11.0 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PGA2 PF07543.7 EGD93456.1 - 1.4 8.7 14.1 1.6 8.5 9.8 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 TATR PF03430.8 EGD93456.1 - 1.4 7.4 5.7 1.4 7.4 4.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Asp-B-Hydro_N PF05279.6 EGD93456.1 - 2.7 7.7 11.0 2.9 7.6 7.6 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC45 PF02724.9 EGD93456.1 - 9 4.1 10.5 11 3.9 7.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_72 PF03198.9 EGD93457.1 - 2.4e-133 443.9 7.2 3.1e-133 443.6 5.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EGD93457.1 - 6.1e-27 93.9 4.0 2.3e-26 92.0 2.8 2.1 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EGD93457.1 - 2.3e-06 26.7 0.5 3.5e-06 26.1 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EGD93457.1 - 0.002 17.4 1.4 0.56 9.3 0.1 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) SprT-like PF10263.4 EGD93458.1 - 6.6e-46 155.8 0.4 1.1e-45 155.0 0.3 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_M30 PF10460.4 EGD93458.1 - 0.036 12.9 0.1 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 Peptidase M30 DUF1043 PF06295.7 EGD93458.1 - 0.33 10.6 2.6 1.6 8.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Mog1 PF04603.7 EGD93459.1 - 2.9e-15 56.4 0.0 2.1e-10 40.6 0.0 2.9 1 1 0 2 2 2 2 Ran-interacting Mog1 protein NYN PF01936.13 EGD93460.1 - 0.00037 20.7 0.0 0.0052 17.0 0.0 2.3 1 1 0 1 1 1 1 NYN domain HSP9_HSP12 PF04119.7 EGD93461.1 - 2.5e-25 88.3 5.5 2.5e-25 88.2 2.3 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 COG6 PF06419.6 EGD93462.1 - 1.3e-221 737.0 0.5 1.4e-221 736.9 0.4 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Transcrip_act PF04949.8 EGD93462.1 - 0.0032 17.1 0.2 0.018 14.6 0.1 2.3 2 1 0 2 2 2 1 Transcriptional activator COG2 PF06148.6 EGD93462.1 - 0.015 15.1 1.2 6.5 6.6 0.0 3.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NIF3 PF01784.13 EGD93463.1 - 2.5e-50 171.3 0.0 6.4e-50 169.9 0.0 1.6 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 EGD93464.1 - 5.1e-21 74.4 0.0 6.9e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Redoxin PF08534.5 EGD93465.1 - 7.1e-31 106.7 0.0 8.3e-31 106.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGD93465.1 - 3.5e-09 36.4 0.0 4.3e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.12 EGD93466.1 - 1.3e-37 128.1 0.2 1.3e-37 128.1 0.1 2.3 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 EGD93466.1 - 2.2e-21 75.9 0.0 2.2e-21 75.9 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain W2 PF02020.13 EGD93469.1 - 1.8e-16 59.8 0.9 1.8e-16 59.8 0.6 2.9 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EGD93469.1 - 4.6e-12 44.8 14.5 0.00013 21.3 1.9 3.5 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGD93469.1 - 7.8e-06 25.3 11.0 0.00056 19.4 2.8 2.8 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 EGD93469.1 - 0.00013 21.3 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase IBR PF01485.16 EGD93470.1 - 9.2e-23 79.8 46.7 5.3e-12 45.4 3.9 4.4 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 EGD93470.1 - 6.3e-06 26.1 7.8 6.3e-06 26.1 5.4 4.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 EGD93470.1 - 0.00062 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_2 PF13639.1 EGD93470.1 - 0.00081 19.1 8.0 0.00081 19.1 5.5 3.5 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EGD93470.1 - 0.0013 18.3 5.4 0.0013 18.3 3.7 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD93470.1 - 0.0028 17.3 9.2 0.0028 17.3 6.4 3.1 3 0 0 3 3 3 2 zinc-RING finger domain AceK PF06315.6 EGD93470.1 - 0.061 11.6 0.2 0.083 11.1 0.1 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Mito_carr PF00153.22 EGD93471.1 - 2.2e-70 232.4 6.8 1.4e-24 85.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PBP-Tp47_a PF14889.1 EGD93471.1 - 0.073 12.3 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Penicillin-binding protein Tp47 domain a tRNA-synt_1 PF00133.17 EGD93472.1 - 2.6e-36 124.8 0.0 8.6e-26 90.0 0.0 3.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EGD93472.1 - 4.9e-17 61.6 0.0 3.3e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGD93472.1 - 2.6e-11 43.5 0.0 7.1e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGD93472.1 - 3.4e-07 29.6 0.0 6.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EGD93472.1 - 0.013 14.1 0.0 0.12 10.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) L51_S25_CI-B8 PF05047.11 EGD93473.1 - 8.6e-14 51.0 0.0 1.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LRS4 PF10422.4 EGD93473.1 - 0.21 10.9 3.0 0.29 10.4 2.1 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF1751 PF08551.5 EGD93474.1 - 1.8e-28 98.7 0.5 3.9e-28 97.6 0.3 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EGD93474.1 - 4.2e-06 26.8 11.2 9e-06 25.7 7.8 1.5 1 0 0 1 1 1 1 Rhomboid family WD40 PF00400.27 EGD93475.1 - 2.1e-08 33.7 2.7 0.02 14.7 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.6 EGD93475.1 - 0.011 15.4 0.0 0.031 13.9 0.0 1.8 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 EGD93475.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 LisH Rif1_N PF12231.3 EGD93476.1 - 0.025 13.5 0.3 0.036 13.0 0.2 1.1 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal V_ATPase_I PF01496.14 EGD93476.1 - 0.17 9.6 1.8 0.23 9.2 1.0 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family AATF-Che1 PF13339.1 EGD93476.1 - 0.46 10.6 3.0 1.1 9.3 0.7 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Chorismate_bind PF00425.13 EGD93477.1 - 7.6e-71 238.4 0.0 1.1e-70 237.9 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EGD93477.1 - 1.6e-21 76.7 0.0 2.4e-18 66.5 0.0 3.4 3 1 1 4 4 4 2 Anthranilate synthase component I, N terminal region DUF1720 PF08226.6 EGD93478.1 - 0.00027 20.9 36.1 0.00027 20.9 25.0 5.7 2 2 2 4 4 4 2 Domain of unknown function (DUF1720) Pkinase PF00069.20 EGD93479.1 - 5.4e-11 42.1 0.0 2.9e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93479.1 - 1.4e-06 27.6 0.0 6.9e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGD93479.1 - 0.0036 17.0 0.1 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD93479.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT_2 PF13646.1 EGD93480.1 - 7.9e-07 29.2 0.0 0.003 17.8 0.1 3.3 2 1 1 3 3 3 2 HEAT repeats Adaptin_N PF01602.15 EGD93480.1 - 4.2e-05 22.0 0.3 0.00036 19.0 0.2 2.5 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EGD93480.1 - 0.00013 21.7 0.0 0.19 11.9 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat TPR_MLP1_2 PF07926.7 EGD93480.1 - 0.00099 18.8 4.5 0.0021 17.8 0.3 2.5 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.1 EGD93480.1 - 0.039 13.1 5.8 0.087 11.9 4.0 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 IncA PF04156.9 EGD93480.1 - 0.053 13.1 15.2 0.015 14.9 6.9 2.2 2 0 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 EGD93480.1 - 0.056 11.3 3.3 0.084 10.7 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 EGD93480.1 - 0.07 11.7 9.0 0.13 10.9 6.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 EGD93480.1 - 0.079 11.9 11.9 0.19 10.7 8.3 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Macoilin PF09726.4 EGD93480.1 - 0.11 10.7 7.8 0.24 9.6 5.4 1.5 1 0 0 1 1 1 0 Transmembrane protein Latarcin PF10279.4 EGD93480.1 - 0.19 11.9 3.1 5.4 7.2 3.1 2.6 3 1 0 3 3 3 0 Latarcin precursor HsbA PF12296.3 EGD93480.1 - 0.68 9.7 4.7 4.1 7.2 0.1 3.9 4 0 0 4 4 4 0 Hydrophobic surface binding protein A AAA_13 PF13166.1 EGD93480.1 - 2.7 6.3 7.7 0.33 9.3 1.9 1.7 2 0 0 2 2 2 0 AAA domain NYD-SP28_assoc PF14775.1 EGD93480.1 - 2.9 7.6 5.4 4.7 6.9 0.6 2.8 1 1 1 2 2 2 0 Sperm tail C-terminal domain HALZ PF02183.13 EGD93480.1 - 4.2 7.1 7.7 1.1 9.0 1.9 2.7 2 1 0 2 2 2 0 Homeobox associated leucine zipper TMF_DNA_bd PF12329.3 EGD93480.1 - 8.5 6.2 15.4 2.5 7.9 3.2 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Ribosomal_L7Ae PF01248.21 EGD93481.1 - 1e-20 72.9 0.3 1.7e-20 72.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1048 PF06304.6 EGD93481.1 - 0.032 14.5 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) Clat_adaptor_s PF01217.15 EGD93483.1 - 1.8e-42 144.4 0.0 2.9e-42 143.7 0.0 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MMR_HSR1 PF01926.18 EGD93484.1 - 2.3e-18 66.2 0.0 3.3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGD93484.1 - 6.2e-07 28.7 0.0 7.9e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EGD93484.1 - 2.4e-06 27.4 0.0 0.00016 21.5 0.0 2.4 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 EGD93484.1 - 1.4e-05 24.5 0.0 0.00013 21.4 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGD93484.1 - 0.00026 20.1 0.2 0.00068 18.8 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EGD93484.1 - 0.0015 17.8 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EGD93484.1 - 0.0022 17.2 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EGD93484.1 - 0.008 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EGD93484.1 - 0.0094 14.9 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.4 EGD93484.1 - 0.078 12.4 0.0 0.19 11.2 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.27 EGD93485.1 - 1.8e-54 179.7 15.0 3.3e-09 36.2 0.0 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EGD93485.1 - 2.5e-10 39.9 0.1 6e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD93485.1 - 2.9e-10 39.5 0.2 5.7e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EGD93485.1 - 4.4e-05 21.8 9.8 0.26 9.3 0.4 5.1 3 3 2 5 5 5 4 Nucleoporin Nup120/160 PRANC PF09372.5 EGD93485.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 PRANC domain PQQ_2 PF13360.1 EGD93485.1 - 0.18 11.1 2.5 1 8.7 0.1 2.6 3 0 0 3 3 3 0 PQQ-like domain HORMA PF02301.13 EGD93486.1 - 1.3e-50 171.8 0.1 2.9e-50 170.6 0.0 1.6 2 0 0 2 2 2 1 HORMA domain Nuc_sug_transp PF04142.10 EGD93488.1 - 4.5e-66 222.4 2.8 4.5e-66 222.4 2.0 1.6 1 1 1 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 EGD93488.1 - 0.00032 20.7 10.8 0.00032 20.7 7.5 2.8 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EGD93488.1 - 0.0029 17.7 7.1 0.0029 17.7 5.0 2.8 2 2 0 2 2 2 1 Multidrug resistance efflux transporter UAA PF08449.6 EGD93488.1 - 0.057 12.3 10.7 1.3 7.8 7.4 2.6 1 1 0 1 1 1 0 UAA transporter family Sec63 PF02889.11 EGD93489.1 - 1.3e-54 185.5 0.0 1.9e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EGD93489.1 - 1.4e-28 99.5 0.1 2.8e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD93489.1 - 2.9e-10 39.8 0.0 6.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD93489.1 - 3.4e-10 40.0 0.0 8.1e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EGD93489.1 - 3.4e-05 22.7 0.1 8.2e-05 21.5 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EGD93489.1 - 0.0053 16.8 0.0 0.018 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGD93489.1 - 0.015 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EGD93489.1 - 0.025 14.8 0.0 0.068 13.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EGD93489.1 - 0.073 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein LRR_1 PF00560.28 EGD93490.1 - 0.00014 21.4 1.2 1.5 9.1 0.1 4.1 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_8 PF13855.1 EGD93490.1 - 0.00033 20.3 0.3 0.004 16.8 0.0 2.6 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.1 EGD93490.1 - 0.0047 16.8 7.1 2.7 8.3 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.2 EGD93490.1 - 0.0062 16.1 0.9 0.033 13.8 0.5 2.2 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGD93490.1 - 0.35 11.2 3.1 6.2 7.4 0.2 3.6 3 0 0 3 3 3 0 Leucine rich repeat Acid_PPase PF12689.2 EGD93491.1 - 7.6e-68 227.4 0.0 8.8e-68 227.2 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.13 EGD93491.1 - 0.0011 18.6 0.0 0.0016 18.1 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EGD93491.1 - 0.0032 17.7 0.3 0.095 12.9 0.0 2.8 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hexapep PF00132.19 EGD93492.1 - 2e-09 36.4 9.7 0.0011 18.4 2.9 4.3 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGD93492.1 - 3.4e-06 26.4 1.9 0.0053 16.2 0.9 3.4 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase TPR_MLP1_2 PF07926.7 EGD93493.1 - 1.8e-31 108.6 27.7 1.8e-31 108.6 19.2 15.9 4 4 7 12 12 12 4 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EGD93493.1 - 0.00019 21.1 14.7 0.00019 21.1 10.2 22.0 12 7 10 25 25 25 6 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 EGD93493.1 - 0.0018 18.1 16.1 0.0018 18.1 11.2 15.6 4 4 11 16 16 16 3 Tropomyosin like TFIIE_beta PF02186.10 EGD93494.1 - 1.1e-06 28.5 0.0 3.7e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 TFIIE beta subunit core domain DHBP_synthase PF00926.14 EGD93495.1 - 2.5e-63 212.8 0.0 6.5e-63 211.4 0.0 1.6 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase F-box PF00646.28 EGD93496.1 - 1.5e-08 34.0 1.3 3e-08 33.0 0.9 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD93496.1 - 4.7e-07 29.4 1.9 9.6e-07 28.4 1.3 1.5 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 EGD93497.1 - 1.4e-60 204.6 0.0 8.4e-60 202.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93497.1 - 8.7e-26 90.5 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD93497.1 - 2.4e-10 39.8 0.0 3.2e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGD93497.1 - 0.0097 14.9 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD93497.1 - 0.11 12.1 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family UQ_con PF00179.21 EGD93498.1 - 1.7e-48 163.6 0.0 2e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGD93498.1 - 0.0002 21.2 0.3 0.00037 20.3 0.2 1.6 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EGD93498.1 - 0.0026 17.4 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGD93498.1 - 0.0036 16.9 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain Nucleos_tra2_C PF07662.8 EGD93499.1 - 2.4e-69 233.0 1.3 2.4e-69 233.0 0.9 3.2 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EGD93499.1 - 2.3e-22 79.0 4.3 2.3e-22 79.0 3.0 3.1 2 1 1 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Prenyltransf PF01255.14 EGD93501.1 - 5e-71 238.3 0.0 6.4e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase UbiA PF01040.13 EGD93502.1 - 7.2e-13 48.3 0.1 9.7e-13 47.9 0.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Glyco_transf_20 PF00982.16 EGD93503.1 - 7.1e-200 664.4 0.0 8.1e-200 664.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EGD93503.1 - 0.0099 15.3 0.4 0.036 13.5 0.1 2.1 2 1 0 2 2 2 1 Starch synthase catalytic domain MIT PF04212.13 EGD93503.1 - 0.29 11.0 2.4 17 5.3 0.0 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Lactamase_B PF00753.22 EGD93504.1 - 2.8e-21 76.0 0.9 4.1e-21 75.5 0.6 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGD93504.1 - 5.1e-05 22.8 0.2 6.4e-05 22.5 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGD93504.1 - 0.0012 18.5 0.1 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Aconitase PF00330.15 EGD93505.1 - 3.6e-175 582.9 0.0 7.9e-175 581.7 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGD93505.1 - 3.2e-45 153.4 0.0 5.7e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 EGD93506.1 - 1.5e-08 34.5 2.9 1.5e-08 34.5 2.0 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 EGD93506.1 - 0.0056 16.2 0.8 0.0083 15.6 0.2 1.7 2 0 0 2 2 2 1 U1 zinc finger zf-C2H2_2 PF12756.2 EGD93506.1 - 0.069 13.2 0.7 0.099 12.7 0.5 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EGD93506.1 - 6.7 7.0 6.3 1.7 8.9 1.0 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Mito_carr PF00153.22 EGD93507.1 - 4.3e-49 164.1 4.0 7.1e-19 67.3 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein SNF2_N PF00176.18 EGD93508.1 - 2.2e-66 223.6 0.0 2.9e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EGD93508.1 - 2.6e-61 206.8 0.8 4.8e-61 205.9 0.5 1.4 1 0 0 1 1 1 1 Rad54 N terminal ResIII PF04851.10 EGD93508.1 - 0.00017 21.5 0.0 0.00068 19.5 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EGD93508.1 - 0.094 11.5 0.0 0.2 10.4 0.0 1.5 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 AAA_34 PF13872.1 EGD93508.1 - 0.17 10.6 0.0 16 4.1 0.0 2.6 2 1 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 Vac14_Fig4_bd PF11916.3 EGD93509.1 - 7.7e-63 210.9 4.2 7.7e-63 210.9 2.9 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EGD93509.1 - 1.4e-45 153.6 0.1 4.7e-42 142.3 0.0 4.0 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EGD93509.1 - 1.5e-07 30.8 2.2 0.12 12.5 0.0 7.3 8 0 0 8 8 8 1 HEAT repeat HEAT_2 PF13646.1 EGD93509.1 - 3.6e-06 27.1 1.7 0.054 13.7 0.0 4.4 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EGD93509.1 - 7.5e-06 26.2 6.4 0.036 14.5 0.0 5.7 4 1 1 5 5 5 2 HEAT-like repeat APH PF01636.18 EGD93510.1 - 3.3e-13 49.9 0.0 3.6e-12 46.5 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGD93510.1 - 5.4e-06 25.3 0.1 0.0079 14.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.15 EGD93510.1 - 0.00089 18.4 0.0 0.002 17.3 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Gemin7 PF11095.3 EGD93510.1 - 0.042 13.5 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) Glyco_hydro_47 PF01532.15 EGD93512.1 - 1.9e-174 580.5 0.0 2.3e-174 580.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APG9 PF04109.11 EGD93513.1 - 5.4e-122 407.2 6.1 2.1e-117 392.1 3.1 2.2 2 0 0 2 2 2 2 Autophagy protein Apg9 AMP-binding PF00501.23 EGD93514.1 - 1.1e-164 547.7 0.0 1.7e-81 273.7 0.1 2.7 3 0 0 3 3 3 2 AMP-binding enzyme Condensation PF00668.15 EGD93514.1 - 1.1e-63 214.9 0.0 1.5e-33 115.9 0.0 2.9 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.20 EGD93514.1 - 1e-11 44.8 0.2 2.2e-07 31.0 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD93514.1 - 1.2e-08 35.7 0.0 0.0031 18.4 0.0 3.6 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain DUF2400 PF09674.5 EGD93514.1 - 0.069 12.8 0.0 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) RE_HpaII PF09561.5 EGD93514.1 - 0.28 10.3 0.1 0.49 9.5 0.1 1.3 1 0 0 1 1 1 0 HpaII restriction endonuclease SnoaL_2 PF12680.2 EGD93515.1 - 1.5e-05 25.3 0.0 2.9e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EGD93515.1 - 0.084 12.4 0.1 5.2 6.6 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Methyltransf_11 PF08241.7 EGD93516.1 - 1.9e-14 53.9 0.0 3.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD93516.1 - 6.6e-13 48.5 0.0 8.5e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD93516.1 - 5.8e-11 41.9 0.0 9.9e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGD93516.1 - 2e-10 40.9 0.0 3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD93516.1 - 1.9e-08 34.8 0.0 3.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD93516.1 - 5.3e-08 33.1 0.0 9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD93516.1 - 8.1e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD93516.1 - 2.2e-07 30.7 0.0 3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD93516.1 - 0.0005 19.5 0.0 0.0016 17.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 EGD93516.1 - 0.0045 16.0 0.0 0.0066 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 EGD93516.1 - 0.041 13.5 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.2 EGD93517.1 - 4e-12 46.5 0.0 1.2e-11 44.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD93517.1 - 1.1e-09 38.2 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD93517.1 - 3e-09 36.7 0.0 5.3e-08 32.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGD93517.1 - 0.0057 16.1 0.0 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 Putative esterase CENP-K PF11802.3 EGD93518.1 - 0.00033 19.9 0.2 0.13 11.4 0.0 2.5 2 1 0 2 2 2 2 Centromere-associated protein K AAA_13 PF13166.1 EGD93518.1 - 0.013 14.0 4.4 0.024 13.1 2.8 1.6 1 1 0 1 1 1 0 AAA domain DUF3829 PF12889.2 EGD93518.1 - 0.042 13.0 5.7 0.11 11.7 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3829) TMPIT PF07851.8 EGD93518.1 - 0.057 12.4 2.5 0.097 11.7 0.0 2.2 2 1 0 2 2 2 0 TMPIT-like protein Sec20 PF03908.8 EGD93518.1 - 0.12 12.1 1.3 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 Sec20 Syntaxin-6_N PF09177.6 EGD93518.1 - 0.18 12.1 15.9 0.64 10.4 0.9 4.2 2 1 1 4 4 4 0 Syntaxin 6, N-terminal FH2 PF02181.18 EGD93518.1 - 0.56 9.0 6.4 4.9 5.9 0.2 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain Spc7 PF08317.6 EGD93518.1 - 3.8 6.0 11.5 0.85 8.2 3.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein KH_1 PF00013.24 EGD93519.1 - 2.3e-40 136.0 3.1 2.7e-16 58.9 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGD93519.1 - 1.5e-30 104.2 10.0 2.2e-11 43.1 1.3 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EGD93519.1 - 2e-11 43.2 2.9 0.011 15.2 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGD93519.1 - 0.00027 20.5 0.2 1.8 8.2 0.0 3.1 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EGD93519.1 - 0.018 14.8 6.8 1.2 8.9 0.1 3.2 3 0 0 3 3 3 0 NusA-like KH domain AA_permease_2 PF13520.1 EGD93520.1 - 2.6e-52 177.7 41.8 3.3e-52 177.4 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD93520.1 - 5.2e-27 94.3 33.0 7.1e-27 93.8 22.9 1.1 1 0 0 1 1 1 1 Amino acid permease Raptor_N PF14538.1 EGD93522.1 - 0.0057 16.5 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Acetyltransf_1 PF00583.19 EGD93523.1 - 2.4e-09 37.0 0.0 4.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD93523.1 - 5.1e-07 29.7 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD93523.1 - 1.1e-05 25.2 0.0 0.0002 21.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD93523.1 - 2e-05 24.6 0.1 3.4e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EGD93523.1 - 0.011 14.9 0.0 0.041 13.1 0.0 1.7 2 0 0 2 2 2 0 MOZ/SAS family FR47 PF08445.5 EGD93523.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Methyltransf_18 PF12847.2 EGD93524.1 - 0.069 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 EGD93525.1 - 3.1e-14 52.4 0.3 5.2e-14 51.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAT1 PF09770.4 EGD93525.1 - 0.61 8.2 13.4 49 1.9 0.0 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Syntaxin-6_N PF09177.6 EGD93526.1 - 0.14 12.5 0.1 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Microtub_assoc PF07989.6 EGD93526.1 - 0.22 11.3 0.0 3.4 7.5 0.0 2.3 1 1 1 2 2 2 0 Microtubule associated Proteasome PF00227.21 EGD93527.1 - 4e-47 159.9 0.0 4.8e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EGD93527.1 - 1.3e-14 53.0 0.1 2.7e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Methyltransf_23 PF13489.1 EGD93529.1 - 2e-25 89.4 0.0 2.7e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD93529.1 - 7e-11 41.9 0.0 5.6e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD93529.1 - 1.6e-09 38.2 0.0 3.7e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD93529.1 - 2.5e-07 31.1 0.0 4.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD93529.1 - 5.1e-07 30.0 0.0 1.8e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGD93529.1 - 0.00014 21.0 0.3 0.00061 18.8 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EGD93529.1 - 0.0019 18.2 0.0 0.0055 16.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD93529.1 - 0.02 15.2 0.0 0.045 14.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EGD93529.1 - 0.023 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EGD93529.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EGD93529.1 - 0.026 13.6 0.0 0.18 10.8 0.0 2.2 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGD93529.1 - 0.12 11.7 0.0 4.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Peptidase_M3 PF01432.15 EGD93531.1 - 6.2e-121 404.6 0.0 8.6e-121 404.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 O-FucT PF10250.4 EGD93531.1 - 0.12 11.4 0.1 0.32 10.0 0.0 1.6 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase ApoO PF09769.4 EGD93532.1 - 2.6e-49 166.9 1.9 3.5e-49 166.5 0.1 2.0 3 0 0 3 3 3 1 Apolipoprotein O GRASP55_65 PF04495.9 EGD93533.1 - 7.9e-43 145.7 0.0 3.8e-41 140.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Methyltransf_15 PF09445.5 EGD93534.1 - 1.8e-49 167.4 0.0 2.3e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EGD93534.1 - 6.6e-10 39.0 0.0 9.5e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGD93534.1 - 1.6e-09 37.6 0.0 2.1e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 EGD93534.1 - 5.6e-09 35.8 0.0 7.6e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EGD93534.1 - 7.9e-08 31.9 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EGD93534.1 - 4.3e-07 30.5 0.0 5.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD93534.1 - 6.9e-06 25.7 0.0 9.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.14 EGD93534.1 - 0.0033 16.7 0.0 0.0048 16.2 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family MTS PF05175.9 EGD93534.1 - 0.0035 16.7 0.0 0.0047 16.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.12 EGD93534.1 - 0.0078 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.15 EGD93534.1 - 0.022 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Sigma54_activ_2 PF14532.1 EGD93534.1 - 0.038 14.0 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain PrmA PF06325.8 EGD93534.1 - 0.043 12.9 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DNA_methylase PF00145.12 EGD93534.1 - 0.059 12.4 0.0 0.074 12.1 0.0 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DUF3591 PF12157.3 EGD93535.1 - 2.7e-198 659.0 0.2 3.6e-198 658.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EGD93535.1 - 0.0026 17.4 2.8 0.0058 16.2 1.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGD93535.1 - 0.014 15.3 0.9 0.025 14.4 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Prok-E2_E PF14462.1 EGD93535.1 - 0.097 12.2 0.6 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family E Pkinase PF00069.20 EGD93536.1 - 4.1e-48 163.7 0.0 6.1e-28 97.6 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93536.1 - 8.6e-20 70.8 0.0 1.3e-12 47.3 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGD93536.1 - 0.052 13.2 1.5 0.065 12.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family UPF0172 PF03665.8 EGD93536.1 - 0.68 9.3 2.6 0.52 9.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) FKBP_C PF00254.23 EGD93537.1 - 6.3e-30 103.0 0.0 2.7e-29 101.0 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Daxx PF03344.10 EGD93537.1 - 0.44 8.9 42.9 0.11 10.9 12.6 2.1 2 0 0 2 2 2 0 Daxx Family IMS PF00817.15 EGD93538.1 - 3.7e-40 137.1 0.0 9.7e-40 135.7 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGD93538.1 - 1.1e-20 73.9 0.2 5.5e-20 71.5 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EGD93538.1 - 1.5e-11 44.2 5.8 3.6e-07 30.0 0.3 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) BRCT PF00533.21 EGD93538.1 - 3.5e-07 30.2 0.0 9.2e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EGD93538.1 - 0.00025 20.9 0.1 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 EGD93538.1 - 0.0022 17.8 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF1805 PF08827.6 EGD93538.1 - 0.03 14.1 0.0 0.28 10.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1805) HHH_5 PF14520.1 EGD93538.1 - 0.033 14.3 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF4066 PF13278.1 EGD93539.1 - 1.4e-31 109.0 0.0 1.7e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EGD93539.1 - 2.7e-15 56.1 0.0 3.5e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EGD93539.1 - 0.004 16.6 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EGD93539.1 - 0.054 13.0 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF4246 PF14033.1 EGD93540.1 - 4.4e-190 632.5 0.1 5.4e-190 632.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EGD93540.1 - 0.00072 19.7 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Aminotran_1_2 PF00155.16 EGD93541.1 - 2.1e-72 244.0 0.0 2.5e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OMPdecase PF00215.19 EGD93543.1 - 2.1e-75 253.0 0.0 2.4e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.13 EGD93544.1 - 6.5e-24 83.9 4.1 9.1e-24 83.5 2.8 1.2 1 0 0 1 1 1 1 MAPEG family MBOAT PF03062.14 EGD93545.1 - 1e-23 83.9 15.1 1e-23 83.9 10.5 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EGD93545.1 - 0.0054 16.7 2.7 0.016 15.2 1.9 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SieB PF14163.1 EGD93546.1 - 0.056 13.0 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B HTH_Tnp_Tc3_2 PF01498.13 EGD93547.1 - 3.9e-07 30.0 0.7 2.5e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EGD93547.1 - 7.2e-07 28.6 0.2 0.00075 19.0 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.1 EGD93547.1 - 7.4e-07 29.3 0.1 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.1 EGD93547.1 - 5.8e-06 25.7 1.0 0.0061 16.0 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.1 EGD93547.1 - 8.4e-06 26.5 0.3 5.1e-05 23.9 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EGD93547.1 - 6.8e-05 22.2 0.5 0.0052 16.2 0.0 2.8 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_20 PF12840.2 EGD93547.1 - 0.00014 21.5 0.0 0.38 10.5 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_28 PF13518.1 EGD93547.1 - 0.00036 20.4 0.2 0.091 12.7 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.1 EGD93547.1 - 0.00044 19.5 0.8 0.57 9.6 0.1 3.0 2 1 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.5 EGD93547.1 - 0.0059 16.1 0.1 0.057 13.0 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_AsnC-type PF13404.1 EGD93547.1 - 0.031 13.8 0.1 3.6 7.2 0.0 2.4 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_7 PF02796.10 EGD93547.1 - 0.033 14.0 4.8 0.21 11.4 1.7 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_WhiA PF02650.9 EGD93547.1 - 0.048 14.0 0.2 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 WhiA C-terminal HTH domain TrmB PF01978.14 EGD93547.1 - 0.058 13.0 0.1 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sigma70_r1_1 PF03979.9 EGD93547.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Sigma70_r4 PF04545.11 EGD93547.1 - 0.069 12.4 0.0 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_IS630 PF01710.11 EGD93547.1 - 0.078 12.6 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_21 PF13276.1 EGD93547.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 HTH-like domain HTH_psq PF05225.11 EGD93547.1 - 0.11 12.0 0.4 17 5.0 0.0 2.4 2 0 0 2 2 2 0 helix-turn-helix, Psq domain WD40 PF00400.27 EGD93548.1 - 7.6e-49 161.9 27.7 1.2e-08 34.5 1.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat RNase_PH PF01138.16 EGD93549.1 - 3.8e-18 66.0 0.0 8.3e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGD93549.1 - 3.4e-07 30.0 0.2 7.4e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 HAD PF12710.2 EGD93550.1 - 1e-19 71.4 0.0 2.7e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGD93550.1 - 2.6e-19 69.1 0.1 4.3e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGD93550.1 - 3.1e-15 57.1 0.0 3.4e-14 53.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD93550.1 - 3.9e-12 45.9 0.0 2e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGD93550.1 - 0.00053 19.6 0.2 0.0031 17.1 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGD93550.1 - 0.018 15.2 0.1 0.063 13.4 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DNA_pol_lambd_f PF10391.4 EGD93551.1 - 3.5e-20 71.3 1.0 6.3e-20 70.4 0.7 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EGD93551.1 - 9e-19 66.9 0.0 4.4e-18 64.7 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EGD93551.1 - 1.3e-17 63.8 0.0 1.1e-14 54.3 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase beta palm HHH_8 PF14716.1 EGD93551.1 - 1.9e-09 37.5 0.0 4.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Peptidase_S8 PF00082.17 EGD93553.1 - 3e-48 164.4 10.1 4.7e-48 163.7 7.0 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD93553.1 - 2.7e-16 59.8 0.2 5e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 NicO PF03824.11 EGD93554.1 - 2.6e-52 177.8 18.1 2.4e-49 168.1 6.4 2.5 3 0 0 3 3 3 2 High-affinity nickel-transport protein MIG-14_Wnt-bd PF06664.7 EGD93554.1 - 3.2 6.4 6.9 1 8.1 2.6 1.7 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Peptidase_M14 PF00246.19 EGD93555.1 - 2.4e-65 220.9 0.0 3.5e-65 220.3 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase SET PF00856.23 EGD93556.1 - 5.4e-15 56.0 0.2 2.2e-14 54.1 0.1 2.0 1 1 0 1 1 1 1 SET domain SAF PF08666.7 EGD93556.1 - 0.017 15.5 0.0 7.3 7.0 0.0 2.4 2 0 0 2 2 2 0 SAF domain zf-C3HC4_2 PF13923.1 EGD93557.1 - 3.5e-10 39.7 9.9 2.4e-05 24.2 0.9 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD93557.1 - 1.6e-05 24.6 10.4 0.00097 18.9 2.7 2.9 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 EGD93557.1 - 5.2e-05 22.8 11.5 5.4e-05 22.8 3.4 2.7 2 1 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.7 EGD93557.1 - 6.9e-05 22.1 1.8 6.9e-05 22.1 1.2 3.2 2 1 1 3 3 2 2 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EGD93557.1 - 0.00018 21.1 1.7 0.00018 21.1 1.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EGD93557.1 - 0.0024 17.4 8.5 0.003 17.1 0.7 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EGD93557.1 - 0.0057 16.5 16.2 0.15 11.9 5.3 4.1 2 2 1 3 3 3 2 FYVE zinc finger zf-C3HC4_3 PF13920.1 EGD93557.1 - 0.013 15.1 15.0 0.018 14.7 4.7 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SEP PF08059.8 EGD93557.1 - 0.034 14.4 0.0 0.081 13.2 0.0 1.6 1 0 0 1 1 1 0 SEP domain zf-C3HC4_4 PF15227.1 EGD93557.1 - 0.055 13.3 11.2 0.031 14.1 2.6 3.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING DUF1195 PF06708.6 EGD93557.1 - 0.062 12.7 0.2 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) UPF1_Zn_bind PF09416.5 EGD93557.1 - 0.077 12.5 3.6 4.7 6.7 0.1 2.5 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) IBR PF01485.16 EGD93557.1 - 0.1 12.5 9.1 2 8.3 0.4 3.8 3 0 0 3 3 3 0 IBR domain Prok-RING_4 PF14447.1 EGD93557.1 - 0.13 11.7 3.5 0.35 10.4 1.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Siva PF05458.7 EGD93557.1 - 0.52 9.8 5.7 0.11 12.0 0.8 1.9 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Sec7 PF01369.15 EGD93558.1 - 9.2e-37 126.5 0.1 1.5e-36 125.8 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EGD93558.1 - 2.7e-06 27.5 0.0 6.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGD93558.1 - 8e-05 22.7 0.0 0.00022 21.3 0.0 1.8 1 0 0 1 1 1 1 PH domain BTB PF00651.26 EGD93559.1 - 0.0011 18.8 0.1 0.041 13.8 0.0 2.6 3 0 0 3 3 3 1 BTB/POZ domain Endonuclease_NS PF01223.18 EGD93560.1 - 4.6e-60 202.8 0.0 5.9e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Zip PF02535.17 EGD93561.1 - 8.5e-26 90.6 12.9 1e-24 87.1 8.9 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter MFS_1_like PF12832.2 EGD93561.1 - 0.0011 18.7 1.1 0.0025 17.5 0.8 1.6 1 0 0 1 1 1 1 MFS_1 like family DUF2040 PF09745.4 EGD93562.1 - 8.3e-42 142.0 12.7 8.3e-42 142.0 8.8 3.9 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Sedlin_N PF04628.8 EGD93563.1 - 6.4e-39 132.8 0.0 7.7e-39 132.5 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EGD93563.1 - 0.0023 17.6 0.0 0.045 13.4 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family NLBH PF05211.7 EGD93563.1 - 0.052 12.7 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) Herpes_capsid PF06112.6 EGD93563.1 - 0.25 11.3 3.4 0.31 11.0 2.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3678 PF12435.3 EGD93563.1 - 0.56 9.8 6.8 5.5 6.6 3.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Isochorismatase PF00857.15 EGD93564.1 - 3.3e-24 85.7 0.0 1.8e-23 83.3 0.0 1.9 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.10 EGD93564.1 - 0.0014 19.1 0.0 0.0025 18.2 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Hexokinase_2 PF03727.11 EGD93565.1 - 4.9e-20 71.7 0.0 7.6e-18 64.5 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EGD93565.1 - 2e-19 69.7 0.0 9.6e-19 67.5 0.0 2.1 1 1 0 1 1 1 1 Hexokinase NUDE_C PF04880.8 EGD93567.1 - 4.3e-24 85.7 7.8 4.3e-24 85.7 5.4 4.1 4 1 0 4 4 4 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 EGD93567.1 - 0.00014 20.4 27.6 0.0002 19.9 19.1 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Zip PF02535.17 EGD93567.1 - 0.3 10.0 4.5 0.62 9.0 3.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter CCDC144C PF14915.1 EGD93567.1 - 0.38 9.6 26.0 6.2 5.6 18.1 2.3 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region ADIP PF11559.3 EGD93567.1 - 0.42 10.4 26.2 4.1 7.2 3.2 3.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EGD93567.1 - 2.3 7.7 32.4 1.5 8.3 12.6 2.7 2 1 1 3 3 3 0 IncA protein DUF1664 PF07889.7 EGD93567.1 - 3.6 7.3 7.9 0.36 10.6 1.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF904 PF06005.7 EGD93567.1 - 7.8 6.8 32.0 0.11 12.7 5.1 4.5 2 1 1 3 3 3 0 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 EGD93567.1 - 7.9 6.3 32.2 12 5.7 17.5 3.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ACC_central PF08326.7 EGD93568.1 - 7.6e-261 867.2 0.0 9.8e-261 866.8 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EGD93568.1 - 1.3e-181 604.3 0.0 2.3e-181 603.4 0.0 1.4 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EGD93568.1 - 7.7e-54 182.1 0.0 1.5e-53 181.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EGD93568.1 - 9e-24 83.7 0.1 1.7e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGD93568.1 - 8e-23 80.4 0.0 1.2e-19 70.2 0.0 3.1 3 0 0 3 3 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EGD93568.1 - 2e-14 52.9 0.0 5.5e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EGD93568.1 - 4.8e-11 42.7 0.0 1.2e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGD93568.1 - 1.9e-09 36.7 0.0 1e-07 31.0 0.0 2.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EGD93568.1 - 2.4e-05 23.8 0.0 6.6e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EGD93568.1 - 0.00024 21.0 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EGD93568.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 EGD93568.1 - 0.034 13.6 0.0 8.8 5.7 0.0 2.5 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Gryzun PF07919.7 EGD93568.1 - 0.39 8.9 0.0 0.69 8.1 0.0 1.3 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi DUF4487 PF14868.1 EGD93568.1 - 0.81 8.3 0.0 1.2 7.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) HeLo PF14479.1 EGD93569.1 - 0.11 12.2 0.2 0.62 9.7 0.1 2.0 1 1 0 1 1 1 0 Prion-inhibition and propagation RINGv PF12906.2 EGD93570.1 - 1.2e-15 57.2 10.4 2e-15 56.5 7.2 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EGD93570.1 - 0.099 12.4 8.4 0.18 11.6 5.8 1.4 1 0 0 1 1 1 0 Ring finger domain Ycf1 PF05758.7 EGD93570.1 - 0.21 9.2 0.3 0.49 8.0 0.0 1.6 2 0 0 2 2 2 0 Ycf1 zf-C3HC4_3 PF13920.1 EGD93570.1 - 0.23 11.1 5.4 0.38 10.4 3.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AIF-MLS PF14962.1 EGD93570.1 - 0.3 10.7 0.0 0.3 10.7 0.0 2.3 2 0 0 2 2 2 0 Mitochondria Localisation Sequence zf-Apc11 PF12861.2 EGD93570.1 - 0.34 10.7 3.6 0.76 9.6 2.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGD93570.1 - 1.4 8.5 6.9 2.4 7.7 4.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EGD93570.1 - 3.5 7.6 6.7 7.5 6.5 4.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain DUF788 PF05620.6 EGD93572.1 - 1.7e-41 141.9 0.0 1.9e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) TPR_1 PF00515.23 EGD93573.1 - 4.4e-39 130.5 11.5 4.2e-06 26.1 0.0 8.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 EGD93573.1 - 3.6e-36 122.6 26.0 1.4e-12 47.0 1.3 8.0 6 2 2 8 8 8 7 TPR repeat TPR_2 PF07719.12 EGD93573.1 - 8.2e-33 109.6 19.2 0.00051 19.7 0.0 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 EGD93573.1 - 7.6e-27 93.2 22.1 5.5e-21 74.4 0.2 5.1 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGD93573.1 - 8.7e-24 83.6 20.2 2.7e-10 40.6 0.4 8.3 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGD93573.1 - 1.4e-22 79.8 13.6 1.4e-07 31.7 0.3 7.1 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGD93573.1 - 2.7e-21 73.6 5.9 0.00015 21.2 0.4 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGD93573.1 - 4.2e-19 67.2 12.3 0.0047 17.4 0.1 9.9 7 1 3 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGD93573.1 - 8.3e-17 60.8 21.8 2.9e-05 23.9 0.1 7.6 4 2 3 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EGD93573.1 - 2e-13 49.3 14.5 0.0011 18.9 0.0 9.2 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD93573.1 - 9.9e-08 31.2 11.1 3.3 7.7 0.0 8.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGD93573.1 - 4.2e-07 29.9 13.9 0.56 10.7 0.1 7.7 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGD93573.1 - 0.0034 17.1 3.5 0.65 9.8 0.0 4.5 3 1 3 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.5 EGD93573.1 - 0.0057 15.4 0.1 0.34 9.6 0.0 2.3 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) FAT PF02259.18 EGD93573.1 - 0.029 13.3 1.9 0.085 11.8 0.1 2.5 2 1 0 2 2 2 0 FAT domain TPR_21 PF09976.4 EGD93573.1 - 0.67 9.8 5.6 11 5.8 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Acyltransferase PF01553.16 EGD93574.1 - 7.9e-31 106.2 0.0 1.3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ACPS PF01648.15 EGD93575.1 - 5.3e-12 45.5 0.0 3.4e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.14 EGD93577.1 - 8.1e-53 178.8 0.0 4.2e-42 143.9 0.0 2.1 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EGD93577.1 - 1e-08 34.9 0.0 1.2e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EGD93577.1 - 0.00023 20.6 0.0 0.0035 16.8 0.0 2.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EGD93577.1 - 0.00097 18.6 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EGD93577.1 - 0.0061 15.8 0.0 0.0096 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 EGD93577.1 - 0.056 13.1 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 RRM_1 PF00076.17 EGD93578.1 - 1.3e-14 53.5 0.0 1.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD93578.1 - 9.9e-11 41.4 0.0 1.6e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD93578.1 - 6.5e-07 29.1 0.1 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGD93579.1 - 0.012 15.4 0.2 0.12 12.3 0.1 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Rotamase PF00639.16 EGD93581.1 - 2.8e-23 82.4 0.1 3.8e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EGD93581.1 - 2.1e-16 60.2 0.0 2.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EGD93581.1 - 1.5e-09 37.5 0.2 3e-09 36.5 0.2 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EGD93581.1 - 9.8e-07 29.4 0.0 1.3e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain TFIIS_C PF01096.13 EGD93583.1 - 6.5e-15 54.4 2.8 6.5e-15 54.4 1.9 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGD93583.1 - 2.1e-11 43.3 0.8 2.1e-11 43.3 0.6 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 EGD93583.1 - 0.0083 16.4 8.2 0.011 16.0 1.2 2.3 2 0 0 2 2 2 1 Restriction alleviation protein Lar Ogr_Delta PF04606.7 EGD93583.1 - 0.017 14.7 1.8 0.017 14.7 1.3 2.2 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger GFA PF04828.9 EGD93583.1 - 0.075 12.9 10.5 0.24 11.3 0.1 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme C1_4 PF07975.7 EGD93583.1 - 0.86 9.6 13.3 0.22 11.5 1.4 2.6 2 1 0 2 2 2 0 TFIIH C1-like domain zf-ribbon_3 PF13248.1 EGD93583.1 - 0.95 8.7 9.6 0.92 8.8 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_3 PF14369.1 EGD93583.1 - 2.8 8.0 9.4 6.6 6.8 0.1 3.3 3 0 0 3 3 3 0 zinc-finger DZR PF12773.2 EGD93583.1 - 3.1 7.7 15.9 4.2 7.2 2.0 2.9 2 2 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EGD93583.1 - 4.7 7.2 10.9 12 5.9 0.1 3.8 4 0 0 4 4 4 0 Zinc ribbon domain Ribosomal_L14 PF00238.14 EGD93584.1 - 9.5e-46 154.5 1.5 1e-45 154.3 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.23 EGD93585.1 - 5.1e-09 36.6 0.0 1.5e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 SET domain HypA PF01155.14 EGD93585.1 - 0.045 13.4 0.2 0.045 13.4 0.1 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Med19 PF10278.4 EGD93587.1 - 0.089 12.4 0.7 0.089 12.4 0.5 1.8 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DEAD PF00270.24 EGD93588.1 - 5.5e-31 107.3 0.1 1.3e-30 106.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD93588.1 - 1.7e-16 59.8 0.0 4.3e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGD93588.1 - 0.00013 20.9 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGD93588.1 - 0.0014 18.5 0.2 0.013 15.3 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Anillin PF08174.6 EGD93589.1 - 1e-30 106.6 0.4 4.7e-30 104.4 0.3 2.3 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EGD93589.1 - 8.3e-08 32.3 0.0 3.2e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 PH domain DUF3439 PF11921.3 EGD93589.1 - 2.2 8.0 4.6 8.5 6.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PseudoU_synth_1 PF01416.15 EGD93590.1 - 2.3e-23 82.6 0.0 1.1e-10 41.8 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase ATP_bind_2 PF03668.10 EGD93590.1 - 0.021 13.8 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family TFIIE_alpha PF02002.12 EGD93591.1 - 1.4e-18 66.3 0.0 2.9e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_Crp_2 PF13545.1 EGD93591.1 - 0.013 15.2 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain zinc-ribbons_6 PF07191.7 EGD93591.1 - 0.06 13.1 0.2 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbons DUF4182 PF13790.1 EGD93591.1 - 0.065 13.0 2.0 0.3 10.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) zf-FPG_IleRS PF06827.9 EGD93591.1 - 0.082 12.5 1.1 7.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS TrkH PF02386.11 EGD93592.1 - 7.2e-109 363.5 18.2 3.3e-105 351.5 7.0 2.1 2 0 0 2 2 2 2 Cation transport protein NnrU PF07298.6 EGD93592.1 - 0.05 12.9 6.3 0.019 14.3 2.0 2.0 2 0 0 2 2 2 0 NnrU protein MFS_1 PF07690.11 EGD93593.1 - 1.3e-16 60.2 53.5 1.3e-16 60.2 37.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Ycf4 PF02392.11 EGD93593.1 - 1.5 8.0 5.1 3 7.1 3.5 1.6 1 0 0 1 1 1 0 Ycf4 PALP PF00291.20 EGD93594.1 - 1.6e-48 165.5 0.2 1.9e-48 165.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3517 PF12030.3 EGD93595.1 - 6.7e-109 363.4 0.7 1.4e-108 362.4 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.24 EGD93595.1 - 2.6e-48 164.4 0.1 4.2e-48 163.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD93595.1 - 6.3e-20 71.7 0.2 1.4e-19 70.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_P_pop3 PF08228.6 EGD93596.1 - 6.5e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 1 0 1 1 1 1 RNase P subunit Pop3 Hexapep PF00132.19 EGD93597.1 - 6.7e-13 47.5 8.9 4.9e-10 38.4 3.8 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EGD93597.1 - 3.2e-12 46.2 0.1 5.1e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EGD93597.1 - 1.1e-09 37.6 9.9 4.4e-09 35.7 2.8 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Ank_2 PF12796.2 EGD93598.1 - 1.9e-45 153.0 0.5 7.1e-15 55.1 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EGD93598.1 - 4.1e-44 146.2 6.8 4e-10 38.9 0.0 9.3 8 1 1 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 EGD93598.1 - 6.9e-38 128.3 10.7 8.6e-09 35.6 0.1 8.3 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD93598.1 - 5.4e-37 124.9 9.2 9.2e-10 38.4 0.1 7.3 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD93598.1 - 2.4e-30 101.5 6.2 5.1e-07 29.3 0.0 9.2 9 0 0 9 9 9 6 Ankyrin repeat AIRC PF00731.15 EGD93599.1 - 1.2e-59 199.9 1.6 2.3e-59 199.0 1.1 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EGD93599.1 - 1.7e-53 180.5 0.0 3.5e-53 179.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EGD93599.1 - 2.3e-09 37.2 0.1 1.3e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGD93599.1 - 0.00014 21.2 0.1 0.00051 19.3 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 EGD93599.1 - 0.0013 17.5 0.0 0.21 10.3 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon PrpR_N PF06506.6 EGD93599.1 - 0.0016 17.8 1.2 0.024 14.0 0.1 2.5 2 0 0 2 2 2 1 Propionate catabolism activator Dala_Dala_lig_C PF07478.8 EGD93599.1 - 0.007 15.7 0.0 0.52 9.6 0.0 2.4 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus CoA_binding_2 PF13380.1 EGD93599.1 - 0.051 13.7 1.7 14 5.8 0.0 3.4 2 1 1 3 3 3 0 CoA binding domain 2-Hacid_dh_C PF02826.14 EGD93599.1 - 0.077 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SCA7 PF08313.7 EGD93600.1 - 6.6e-34 115.3 0.6 6.6e-34 115.3 0.4 2.2 2 0 0 2 2 2 1 SCA7, zinc-binding domain Neugrin PF06413.6 EGD93600.1 - 0.2 11.4 6.7 0.32 10.8 4.6 1.4 1 0 0 1 1 1 0 Neugrin CDC45 PF02724.9 EGD93600.1 - 3.4 5.6 6.4 4.5 5.1 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein ATP-synt_Eps PF04627.8 EGD93600.1 - 4.8 6.8 5.5 10 5.7 3.8 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain mRNA_cap_enzyme PF01331.14 EGD93601.1 - 8.2e-52 175.6 0.8 1.1e-51 175.3 0.6 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EGD93601.1 - 3.8e-25 88.2 0.0 7.3e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EGD93601.1 - 1.1e-08 34.7 1.0 3.6e-07 29.7 0.7 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_M PF01068.16 EGD93602.1 - 2.2e-56 190.4 0.8 2.4e-44 151.1 0.1 2.7 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGD93602.1 - 5.5e-40 137.0 1.6 1.8e-38 132.1 0.4 2.4 1 1 1 2 2 2 2 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGD93602.1 - 4.8e-28 97.4 0.0 2.8e-27 94.9 0.0 2.4 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region CFEM PF05730.6 EGD93603.1 - 3e-10 39.7 4.5 4.3e-10 39.2 3.1 1.2 1 0 0 1 1 1 1 CFEM domain PT PF04886.7 EGD93603.1 - 0.00013 21.2 12.7 0.0031 16.8 4.4 2.9 2 0 0 2 2 2 2 PT repeat Catalase PF00199.14 EGD93604.1 - 1.2e-171 570.6 0.8 1.4e-171 570.4 0.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGD93604.1 - 0.00048 19.9 0.0 0.0017 18.1 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Brix PF04427.13 EGD93604.1 - 0.083 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Brix domain GMC_oxred_N PF00732.14 EGD93605.1 - 1.1e-47 162.5 0.0 1.5e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGD93605.1 - 1.3e-33 116.2 0.0 2.1e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EGD93605.1 - 0.0025 16.7 0.2 0.0042 16.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD93605.1 - 0.0042 17.0 0.1 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGD93605.1 - 0.0055 15.6 0.4 0.0088 14.9 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EGD93605.1 - 0.021 13.7 2.0 0.056 12.2 1.4 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EGD93605.1 - 0.028 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD93605.1 - 0.053 11.9 0.6 0.074 11.5 0.4 1.1 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EGD93605.1 - 0.07 11.7 0.5 0.1 11.1 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EGD93605.1 - 0.18 11.8 0.0 2.4 8.1 0.0 2.3 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD93605.1 - 0.31 10.0 2.0 0.5 9.3 1.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FPN1 PF06963.7 EGD93606.1 - 1.2e-113 379.8 13.1 7.7e-113 377.1 9.1 1.8 1 1 0 1 1 1 1 Ferroportin1 (FPN1) RNase_T PF00929.19 EGD93607.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Exonuclease eIF-5_eIF-2B PF01873.12 EGD93608.1 - 4.7e-39 132.8 0.0 7.4e-39 132.2 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EGD93608.1 - 2.4e-25 88.2 1.4 6.2e-25 86.9 0.6 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon HK PF02110.10 EGD93609.1 - 1.6e-77 260.0 0.3 1.6e-77 260.0 0.2 1.6 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EGD93609.1 - 7e-59 197.9 2.8 7e-59 197.9 1.9 1.5 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI NMO PF03060.10 EGD93609.1 - 0.00034 19.8 0.1 0.00072 18.8 0.1 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase QRPTase_C PF01729.14 EGD93609.1 - 0.00037 20.0 0.1 0.00082 18.9 0.1 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain PfkB PF00294.19 EGD93609.1 - 0.012 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EGD93609.1 - 0.013 14.6 0.0 0.035 13.3 0.0 1.7 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Isochorismatase PF00857.15 EGD93610.1 - 5.6e-27 94.7 0.0 7e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF4569 PF15133.1 EGD93611.1 - 0.022 14.1 0.1 0.023 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Frag1 PF10277.4 EGD93612.1 - 0.048 13.1 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family CDV3 PF15359.1 EGD93614.1 - 0.43 10.6 8.3 1.5 8.9 2.1 2.6 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Lipase_GDSL_2 PF13472.1 EGD93615.1 - 3.1e-22 79.5 0.0 4e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGD93615.1 - 2e-20 73.6 0.0 2.4e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Voltage_CLC PF00654.15 EGD93616.1 - 1.6e-93 313.5 22.1 3.2e-93 312.5 13.6 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel DHFR_1 PF00186.14 EGD93617.1 - 4.1e-18 65.4 0.0 3.8e-09 36.3 0.0 3.5 3 1 0 3 3 3 3 Dihydrofolate reductase Med22 PF06179.7 EGD93618.1 - 1e-21 76.9 1.4 1.3e-21 76.6 0.9 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex GPW_gp25 PF04965.9 EGD93618.1 - 0.029 13.8 0.7 0.063 12.8 0.1 1.7 2 0 0 2 2 2 0 Gene 25-like lysozyme Phi-29_GP16_7 PF06720.6 EGD93618.1 - 0.22 11.1 1.5 13 5.4 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 Cwf_Cwc_15 PF04889.7 EGD93620.1 - 6.5e-88 294.5 14.2 7.3e-88 294.3 9.8 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 EGD93620.1 - 0.00033 20.2 2.3 0.00047 19.7 1.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2890 PF11081.3 EGD93620.1 - 0.016 15.2 14.6 0.015 15.3 9.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) SDA1 PF05285.7 EGD93620.1 - 0.054 12.7 17.0 0.064 12.5 11.8 1.1 1 0 0 1 1 1 0 SDA1 IncA PF04156.9 EGD93620.1 - 1.5 8.3 9.1 2.1 7.9 6.3 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EGD93620.1 - 2.1 7.3 9.0 2.5 7.0 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3827 PF12877.2 EGD93620.1 - 3.2 5.7 8.1 4.3 5.3 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Tom37_C PF11801.3 EGD93620.1 - 6.3 6.6 6.0 9.7 6.0 4.2 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Herpes_UL43 PF05072.8 EGD93621.1 - 0.0093 14.7 0.2 0.01 14.5 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL43 protein Tmemb_170 PF10190.4 EGD93621.1 - 0.06 13.3 4.1 0.074 13.1 2.8 1.1 1 0 0 1 1 1 0 Putative transmembrane protein 170 DUF4233 PF14017.1 EGD93621.1 - 3.6 7.5 8.8 6.2 6.7 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) ICMT PF04140.9 EGD93623.1 - 2.9e-29 101.1 0.3 2.9e-29 101.1 0.2 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EGD93623.1 - 1.8e-13 50.5 3.8 1.8e-13 50.5 2.6 2.0 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EGD93623.1 - 1.6e-05 24.3 0.4 2.6e-05 23.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4229 PF14012.1 EGD93623.1 - 0.44 10.4 6.9 6.4 6.7 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Neugrin PF06413.6 EGD93624.1 - 2e-09 37.6 3.8 3.7e-09 36.7 2.7 1.5 1 1 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EGD93624.1 - 2e-06 27.8 12.1 4.8e-06 26.6 8.4 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_DeoR PF08220.7 EGD93624.1 - 0.033 13.7 0.0 0.085 12.4 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_7 PF02796.10 EGD93624.1 - 0.076 12.8 0.2 0.56 10.1 0.0 2.6 3 1 0 3 3 3 0 Helix-turn-helix domain of resolvase Rgp1 PF08737.5 EGD93625.1 - 1.1e-110 370.5 0.0 2.2e-110 369.5 0.0 1.5 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 EGD93625.1 - 0.00091 19.0 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EGD93625.1 - 0.0062 16.6 0.0 0.33 11.0 0.0 3.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Mob1_phocein PF03637.12 EGD93626.1 - 2.2e-70 235.8 0.1 2.7e-70 235.5 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 EGD93627.1 - 3.4e-38 131.1 1.4 5.3e-38 130.5 0.9 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit CAP-ZIP_m PF15255.1 EGD93628.1 - 0.036 14.0 0.2 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 WASH complex subunit CAP-Z interacting, central region Sugarporin_N PF11471.3 EGD93628.1 - 0.094 12.3 1.0 0.18 11.4 0.7 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Bromodomain PF00439.20 EGD93629.1 - 6.4e-14 51.6 0.0 1.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Diphthamide_syn PF01866.12 EGD93630.1 - 2.2e-115 385.1 0.0 2.6e-115 384.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HMGL-like PF00682.14 EGD93631.1 - 1.1e-37 130.0 0.0 3.5e-37 128.3 0.0 1.7 1 1 0 1 1 1 1 HMGL-like DUF1674 PF07896.7 EGD93632.1 - 2e-17 63.1 4.5 4e-17 62.1 3.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) MSA_2 PF00985.12 EGD93632.1 - 0.15 12.2 2.5 0.17 12.0 1.7 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family ORC6 PF05460.8 EGD93632.1 - 0.48 9.4 3.9 0.52 9.3 2.7 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Aminotran_3 PF00202.16 EGD93633.1 - 5.8e-97 324.5 0.0 7.3e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGD93633.1 - 3.6e-05 22.8 0.0 0.00012 21.1 0.0 1.8 1 1 1 2 2 2 1 Aminotransferase class I and II Abhydrolase_3 PF07859.8 EGD93634.1 - 7.8e-34 117.1 0.0 4.1e-23 82.0 0.0 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 EGD93634.1 - 0.094 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF2424 PF10340.4 EGD93634.1 - 0.28 9.7 0.0 0.48 8.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) CLN3 PF02487.12 EGD93635.1 - 1e-94 317.6 21.3 1.2e-86 291.0 8.4 2.9 1 1 1 2 2 2 2 CLN3 protein Rxt3 PF08642.5 EGD93636.1 - 2.1e-25 89.1 2.6 1.5e-24 86.4 0.0 2.8 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EGD93636.1 - 0.00039 20.3 0.0 0.0057 16.6 0.0 2.5 2 0 0 2 2 2 1 LCCL domain Carn_acyltransf PF00755.15 EGD93637.1 - 1.1e-182 608.3 0.0 1.2e-182 608.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase priB_priC PF07445.7 EGD93638.1 - 0.001 18.6 1.9 0.0018 17.7 0.1 2.0 2 0 0 2 2 2 1 Primosomal replication protein priB and priC bZIP_1 PF00170.16 EGD93638.1 - 0.014 15.3 0.3 0.014 15.3 0.2 1.9 2 0 0 2 2 2 0 bZIP transcription factor DUF2968 PF11180.3 EGD93638.1 - 0.053 12.9 0.3 0.053 12.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DivIVA PF05103.8 EGD93638.1 - 0.053 13.5 0.8 0.053 13.5 0.6 2.2 2 0 0 2 2 2 0 DivIVA protein DUF2046 PF09755.4 EGD93638.1 - 0.47 9.2 8.8 0.079 11.8 3.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Spc24 PF08286.6 EGD93638.1 - 4.1 7.1 7.5 17 5.1 1.2 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.6 EGD93638.1 - 5 7.1 5.1 6.1 6.8 1.0 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Spc34 PF08657.5 EGD93638.1 - 6.6 6.3 10.5 2.1 7.9 0.2 2.5 3 0 0 3 3 3 0 DASH complex subunit Spc34 MerR-DNA-bind PF09278.6 EGD93638.1 - 8.5 6.8 11.7 0.81 10.1 0.3 2.4 2 0 0 2 2 2 0 MerR, DNA binding Pyr_redox_2 PF07992.9 EGD93639.1 - 0.00071 19.5 0.0 0.11 12.3 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD93639.1 - 0.0011 19.0 0.0 0.55 10.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD93639.1 - 0.052 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGD93639.1 - 0.088 11.2 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.15 EGD93639.1 - 0.13 12.3 0.0 93 3.1 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Lectin_C PF00059.16 EGD93640.1 - 8.8e-05 23.1 2.2 0.00017 22.1 0.3 2.3 2 0 0 2 2 2 1 Lectin C-type domain Sec62 PF03839.11 EGD93641.1 - 1.6e-51 174.9 0.1 3e-51 174.0 0.1 1.4 1 0 0 1 1 1 1 Translocation protein Sec62 Macoilin PF09726.4 EGD93641.1 - 0.04 12.2 3.8 0.081 11.1 2.6 1.4 1 1 0 1 1 1 0 Transmembrane protein DUF3439 PF11921.3 EGD93641.1 - 0.49 10.1 10.0 0.26 11.0 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) MSA-2c PF12238.3 EGD93641.1 - 0.94 9.1 13.0 0.096 12.3 2.1 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c NST1 PF13945.1 EGD93641.1 - 4 7.4 19.1 7.5 6.5 1.1 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator Shisa PF13908.1 EGD93644.1 - 0.0094 16.1 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EGD93644.1 - 0.044 14.1 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cupin_1 PF00190.17 EGD93646.1 - 7.7e-25 87.0 0.0 6.8e-12 45.0 0.0 2.4 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EGD93646.1 - 1.3e-19 69.4 0.6 8.9e-11 41.1 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EGD93646.1 - 5.9e-07 28.7 0.1 0.0023 17.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EGD93646.1 - 0.0041 16.7 0.0 0.74 9.3 0.0 2.6 1 1 1 2 2 2 2 Cupin EcsB PF05975.7 EGD93647.1 - 0.082 11.3 0.4 0.12 10.7 0.3 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Ank_2 PF12796.2 EGD93648.1 - 4.6e-08 33.2 0.3 1.2e-06 28.7 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGD93648.1 - 6.7e-06 25.8 0.3 1.6 9.2 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 EGD93648.1 - 1.9e-05 24.2 0.8 0.019 14.7 0.1 3.4 2 1 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EGD93648.1 - 0.00089 19.7 0.0 0.091 13.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AAA_16 PF13191.1 EGD93648.1 - 0.023 14.6 0.0 0.061 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ClpB_D2-small PF10431.4 EGD93648.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_17 PF13207.1 EGD93648.1 - 0.06 14.1 0.1 0.18 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain SNAP PF14938.1 EGD93649.1 - 1.7e-108 362.0 15.5 2e-108 361.8 10.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EGD93649.1 - 3.9e-07 29.9 11.2 6.8e-05 22.7 2.8 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGD93649.1 - 0.00035 20.2 14.7 0.5 10.4 0.1 6.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGD93649.1 - 0.0019 18.4 4.7 0.23 11.8 0.6 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD93649.1 - 0.0027 17.3 5.5 16 5.6 0.0 5.8 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGD93649.1 - 0.0032 18.0 13.2 0.0087 16.7 1.5 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD93649.1 - 0.0055 16.3 12.0 0.45 10.2 0.4 4.2 1 1 3 4 4 4 3 TPR repeat TPR_14 PF13428.1 EGD93649.1 - 0.036 14.6 10.3 5.2 7.9 0.9 5.1 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGD93649.1 - 0.057 13.2 12.0 0.33 10.8 0.2 5.3 3 1 1 5 5 5 0 Tetratricopeptide repeat NSF PF02071.15 EGD93649.1 - 0.15 12.7 0.4 0.15 12.7 0.3 6.1 6 0 0 6 6 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_6 PF13174.1 EGD93649.1 - 0.88 10.1 16.2 3.4 8.3 0.1 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF726 PF05277.7 EGD93650.1 - 1.5e-114 382.5 0.2 1.5e-114 382.5 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Glu-tRNAGln PF02686.10 EGD93650.1 - 7.4e-05 22.4 1.2 0.00025 20.7 0.2 2.4 3 0 0 3 3 3 1 Glu-tRNAGln amidotransferase C subunit Abhydrolase_6 PF12697.2 EGD93650.1 - 0.00094 19.1 0.0 0.00094 19.1 0.0 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGD93650.1 - 0.018 15.2 0.2 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_1 PF00561.15 EGD93650.1 - 0.044 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD93650.1 - 0.059 13.1 0.4 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family TcdA_TcdB_pore PF12920.2 EGD93650.1 - 0.21 9.4 2.1 0.32 8.8 1.4 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain HlyIII PF03006.15 EGD93651.1 - 1.9e-36 125.5 12.2 2.6e-36 125.1 8.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF202 PF02656.10 EGD93651.1 - 0.099 12.8 0.3 7.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF663 PF04950.7 EGD93652.1 - 1.4e-96 323.0 0.0 2.5e-96 322.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EGD93652.1 - 9.8e-26 89.1 0.0 2.2e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain BING4CT PF08149.6 EGD93653.1 - 1.6e-40 136.4 0.1 1.4e-37 127.0 0.0 3.0 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 EGD93653.1 - 2.5e-05 23.9 0.0 0.0098 15.7 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF4427 PF14468.1 EGD93653.1 - 0.0063 16.2 0.5 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4427) cobW PF02492.14 EGD93654.1 - 3.2e-34 117.9 0.0 3.9e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EGD93654.1 - 1.9e-06 26.9 0.0 0.011 14.5 0.0 2.1 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 EGD93654.1 - 0.0078 16.1 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EGD93654.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGD93654.1 - 0.024 14.9 0.0 0.053 13.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGD93654.1 - 0.025 15.3 0.0 0.051 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGD93654.1 - 0.034 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.22 EGD93654.1 - 0.042 13.2 0.0 2.4 7.5 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.12 EGD93654.1 - 0.053 12.9 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein CbiA PF01656.18 EGD93654.1 - 0.056 12.8 0.1 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_21 PF13304.1 EGD93654.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGD93654.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LIM_bind PF01803.11 EGD93655.1 - 1.5e-53 181.3 0.0 1.5e-53 181.3 0.0 3.8 3 1 1 4 4 4 1 LIM-domain binding protein BRF1 PF07741.8 EGD93655.1 - 2.7 8.2 16.6 1.2 9.4 3.9 2.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain AAA PF00004.24 EGD93656.1 - 6.8e-39 133.0 0.0 7.6e-38 129.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD93656.1 - 6.8e-05 23.0 0.1 0.0018 18.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD93656.1 - 0.00013 22.0 0.1 0.013 15.5 0.0 2.9 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EGD93656.1 - 0.00013 21.0 0.0 0.0003 19.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EGD93656.1 - 0.00035 19.4 0.0 0.00073 18.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EGD93656.1 - 0.00052 19.7 0.0 0.0024 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGD93656.1 - 0.00069 20.4 0.1 0.0027 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGD93656.1 - 0.0014 18.4 0.0 0.0044 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGD93656.1 - 0.0034 16.5 0.1 0.008 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGD93656.1 - 0.0036 17.0 0.2 0.0098 15.6 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EGD93656.1 - 0.0047 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGD93656.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EGD93656.1 - 0.018 15.0 0.0 0.018 15.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EGD93656.1 - 0.021 14.9 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Pex14_N PF04695.8 EGD93656.1 - 0.03 14.3 2.7 0.035 14.1 0.2 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_24 PF13479.1 EGD93656.1 - 0.03 13.9 0.1 0.084 12.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGD93656.1 - 0.048 13.0 0.2 8.3 5.7 0.0 2.4 1 1 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 EGD93656.1 - 0.066 12.6 0.2 0.31 10.4 0.1 1.9 1 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EGD93656.1 - 0.087 12.4 0.1 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain DUF4337 PF14235.1 EGD93656.1 - 0.093 12.5 0.1 0.27 11.0 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4337) IPT PF01745.11 EGD93656.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase SHQ1 PF04925.10 EGD93656.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 SHQ1 protein Sigma54_activat PF00158.21 EGD93656.1 - 0.18 11.2 0.2 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 EGD93656.1 - 0.28 11.4 0.1 0.28 11.4 0.0 2.3 3 0 0 3 3 2 0 AAA domain Pkinase PF00069.20 EGD93657.1 - 5.3e-16 58.5 0.0 8.6e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93657.1 - 5e-09 35.6 0.0 2.7e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGD93657.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EGD93657.1 - 0.039 13.3 0.0 0.086 12.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 EGD93657.1 - 0.057 12.2 0.1 0.091 11.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TPR_12 PF13424.1 EGD93658.1 - 0.0013 18.6 4.7 1.6 8.7 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD93658.1 - 0.014 15.0 2.2 5.3 6.7 0.4 3.5 3 0 0 3 3 3 0 TPR repeat TPR_19 PF14559.1 EGD93658.1 - 0.019 15.2 6.9 0.37 11.1 1.4 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGD93658.1 - 0.028 14.3 2.6 12 6.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EGD93658.1 - 0.049 13.7 2.7 3.8 7.7 0.1 3.1 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGD93658.1 - 0.067 13.8 1.2 8 7.2 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4050 PF13259.1 EGD93660.1 - 1.1e-38 131.8 0.0 2e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Mus7 PF09462.5 EGD93661.1 - 8.6e-161 536.8 0.0 1.2e-160 536.3 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family PAPA-1 PF04795.7 EGD93663.1 - 7.7e-29 100.2 4.5 7.7e-29 100.2 3.1 2.6 4 0 0 4 4 4 1 PAPA-1-like conserved region NOA36 PF06524.7 EGD93663.1 - 1.8 7.7 20.8 1.8 7.7 3.8 2.3 2 0 0 2 2 2 0 NOA36 protein Pex14_N PF04695.8 EGD93664.1 - 3.4e-30 104.8 2.4 3.4e-30 104.8 1.6 2.6 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sigma70_ECF PF07638.6 EGD93664.1 - 0.074 12.7 0.2 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 ECF sigma factor Calcipressin PF04847.7 EGD93665.1 - 6.1e-32 110.6 0.4 1.1e-31 109.8 0.3 1.4 1 1 0 1 1 1 1 Calcipressin DUF3394 PF11874.3 EGD93667.1 - 0.049 13.1 0.0 0.054 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Uds1 PF15456.1 EGD93669.1 - 4.1e-31 107.5 4.2 4.1e-31 107.5 2.9 1.7 2 0 0 2 2 2 1 Up-regulated During Septation Spc7 PF08317.6 EGD93669.1 - 0.043 12.4 0.2 0.063 11.9 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 EGD93669.1 - 0.25 11.3 1.7 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.14 EGD93670.1 - 1.4e-44 151.5 3.4 2.1e-44 151.0 2.4 1.2 1 0 0 1 1 1 1 GrpE TPD52 PF04201.10 EGD93670.1 - 0.0029 17.3 1.5 0.0045 16.7 1.1 1.3 1 0 0 1 1 1 1 Tumour protein D52 family PEARLI-4 PF05278.7 EGD93670.1 - 0.063 12.6 2.5 0.096 12.0 1.7 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Focal_AT PF03623.8 EGD93670.1 - 0.066 12.7 0.0 0.15 11.5 0.0 1.7 1 1 0 1 1 1 0 Focal adhesion targeting region Bap31 PF05529.7 EGD93670.1 - 0.43 10.0 4.6 0.32 10.4 2.3 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Phage_GP20 PF06810.6 EGD93670.1 - 0.54 9.6 7.0 1.4 8.3 4.8 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 tRNA-synt_2d PF01409.15 EGD93671.1 - 3.6e-48 163.9 0.0 1.7e-26 92.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EGD93671.1 - 0.00046 20.2 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.22 EGD93672.1 - 3.9e-52 173.9 0.1 1.2e-18 66.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein COX6B PF02297.12 EGD93673.1 - 4e-20 71.6 7.1 4.8e-20 71.3 4.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EGD93673.1 - 0.0035 16.7 1.0 0.0061 15.9 0.7 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain CHCH PF06747.8 EGD93673.1 - 0.0087 15.9 0.9 0.022 14.6 0.7 1.7 1 1 0 1 1 1 1 CHCH domain ketoacyl-synt PF00109.21 EGD93673.1 - 0.018 14.4 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain UCR_hinge PF02320.11 EGD93673.1 - 0.08 12.8 0.2 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 EGD93673.1 - 0.63 9.9 5.2 1.4 8.8 1.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) RRM_1 PF00076.17 EGD93675.1 - 4.2e-16 58.3 0.0 5.8e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD93675.1 - 4.1e-11 42.6 0.0 5.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD93675.1 - 4.1e-09 36.1 0.0 5.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGD93676.1 - 2.7e-17 61.9 9.0 3e-05 23.7 0.0 6.6 5 1 1 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 EGD93676.1 - 5.5e-13 48.9 0.1 2.4e-12 46.8 0.0 2.2 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EGD93676.1 - 0.00044 20.0 0.1 0.0029 17.4 0.1 2.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 EGD93676.1 - 0.01 15.6 0.2 0.087 12.6 0.0 2.4 2 0 0 2 2 2 0 Prp18 domain Transp_cyt_pur PF02133.10 EGD93677.1 - 2.1e-23 82.5 27.7 1.6e-13 50.0 1.3 2.1 1 1 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1418 PF07214.7 EGD93677.1 - 1.8 8.2 5.7 2.1 8.0 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) ATE_C PF04377.10 EGD93678.1 - 9.6e-31 106.4 1.0 1.9e-30 105.5 0.7 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EGD93678.1 - 2.8e-22 78.3 3.6 5.6e-22 77.3 2.5 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 EGD93678.1 - 0.028 14.3 0.1 0.098 12.6 0.1 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Phage_Gp14 PF10666.4 EGD93678.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Phage protein Gp14 NUDIX PF00293.23 EGD93679.1 - 6.3e-18 64.7 0.2 7.4e-18 64.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain TraI_2 PF07514.6 EGD93679.1 - 0.02 13.6 0.2 0.029 13.1 0.1 1.2 1 0 0 1 1 1 0 Putative helicase RNA_pol_A_bac PF01000.21 EGD93680.1 - 1.4e-30 105.6 0.0 2.2e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGD93680.1 - 1e-10 40.5 0.0 1.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Baculo_PEP_C PF04513.7 EGD93681.1 - 0.087 12.6 5.7 0.45 10.3 0.1 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_C PF00034.16 EGD93684.1 - 2.2e-09 37.9 0.0 6.9e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EGD93684.1 - 6.4e-08 32.6 0.9 6.4e-08 32.6 0.6 2.3 2 1 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III CCP_MauG PF03150.9 EGD93684.1 - 0.016 15.4 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrom_C550 PF14495.1 EGD93684.1 - 0.025 14.0 0.1 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c-550 domain DUF793 PF05633.6 EGD93684.1 - 0.033 12.9 0.0 0.043 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Subtilosin_A PF11420.3 EGD93684.1 - 0.62 10.1 0.1 0.62 10.1 0.1 2.4 3 0 0 3 3 3 0 Bacteriocin subtilosin A Orbi_NS3 PF01616.11 EGD93685.1 - 0.041 12.8 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Orbivirus NS3 Ferritin-like PF12902.2 EGD93685.1 - 0.063 12.8 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Ferritin-like RNase_PH PF01138.16 EGD93686.1 - 5.9e-13 49.2 0.1 2.1e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Metallophos PF00149.23 EGD93688.1 - 2.1e-06 27.2 0.7 1.5e-05 24.4 0.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD93688.1 - 0.0042 16.9 0.0 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain dCMP_cyt_deam_1 PF00383.17 EGD93689.1 - 4.7e-09 35.8 0.0 5.6e-08 32.3 0.0 2.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EGD93689.1 - 3e-05 23.7 0.1 4.9e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Gp49 PF05973.9 EGD93689.1 - 0.036 14.0 0.1 0.13 12.2 0.0 2.0 2 1 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) DUF1666 PF07891.7 EGD93692.1 - 0.092 12.1 0.0 0.1 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) Stn1 PF10451.4 EGD93694.1 - 1.4e-12 47.0 0.3 2.9e-11 42.6 0.2 2.0 1 1 0 1 1 1 1 Telomere regulation protein Stn1 DUF2175 PF09943.4 EGD93694.1 - 0.25 11.4 1.6 0.59 10.2 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Vma12 PF11712.3 EGD93694.1 - 0.36 10.5 5.3 0.62 9.7 3.6 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1423 PF07227.6 EGD93694.1 - 1.1 7.9 7.1 0.31 9.6 3.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) SelP_N PF04592.9 EGD93695.1 - 2.1 7.6 9.8 4.4 6.6 6.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Abhydrolase_6 PF12697.2 EGD93696.1 - 3.9e-17 62.8 0.2 5.5e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD93696.1 - 2.2e-05 24.2 0.0 3.9e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD93696.1 - 0.001 18.6 0.0 0.0056 16.2 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold F-box-like PF12937.2 EGD93697.1 - 0.00044 19.9 0.1 0.0014 18.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.8 EGD93697.1 - 1.6 9.3 6.2 81 3.9 0.0 5.2 6 0 0 6 6 6 0 Leucine Rich Repeat APH PF01636.18 EGD93699.1 - 2.3e-12 47.1 0.0 3.2e-11 43.4 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGD93699.1 - 0.089 11.4 0.1 1.2 7.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Stc1 PF12898.2 EGD93700.1 - 3.1e-23 81.6 10.6 5.8e-23 80.7 7.4 1.5 1 0 0 1 1 1 1 Stc1 domain F-box PF00646.28 EGD93702.1 - 0.0053 16.3 1.1 0.015 14.9 0.1 2.2 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.2 EGD93702.1 - 0.0054 16.4 0.0 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like Daxx PF03344.10 EGD93705.1 - 0.013 14.0 5.7 0.013 14.0 3.9 1.0 1 0 0 1 1 1 0 Daxx Family U79_P34 PF03064.11 EGD93705.1 - 0.036 13.6 6.2 0.04 13.4 4.3 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Sporozoite_P67 PF05642.6 EGD93705.1 - 0.043 11.6 2.1 0.043 11.6 1.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2890 PF11081.3 EGD93705.1 - 0.051 13.6 5.4 0.057 13.4 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 EGD93705.1 - 0.093 10.6 4.0 0.097 10.5 2.8 1.1 1 0 0 1 1 1 0 Nop14-like family NESP55 PF06390.7 EGD93705.1 - 0.12 11.7 5.8 0.15 11.4 4.0 1.1 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF2514 PF10721.4 EGD93705.1 - 0.16 11.6 6.4 0.17 11.5 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) HSP90 PF00183.13 EGD93705.1 - 0.18 10.1 5.7 0.19 10.0 3.9 1.0 1 0 0 1 1 1 0 Hsp90 protein TEX19 PF15553.1 EGD93705.1 - 0.23 11.3 2.8 0.28 11.0 2.0 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF3682 PF12446.3 EGD93705.1 - 0.36 11.1 12.4 0.53 10.5 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Nucleoplasmin PF03066.10 EGD93705.1 - 0.81 9.1 6.6 1.1 8.8 4.6 1.1 1 0 0 1 1 1 0 Nucleoplasmin RNase_H2-Ydr279 PF09468.5 EGD93705.1 - 1 8.4 7.4 1.3 8.2 5.1 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Paf1 PF03985.8 EGD93705.1 - 1.7 7.3 9.4 1.9 7.1 6.5 1.0 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 EGD93705.1 - 1.7 6.5 4.3 1.8 6.5 3.0 1.0 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.3 EGD93705.1 - 1.9 7.1 8.4 2.2 6.9 5.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 EGD93705.1 - 3.1 7.6 6.9 3.4 7.4 4.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pkinase PF00069.20 EGD93706.1 - 1.3e-62 211.3 0.0 2.8e-62 210.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93706.1 - 1e-32 113.2 0.0 8.3e-32 110.2 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGD93706.1 - 0.05 12.3 0.0 0.071 11.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MbeB_N PF04837.7 EGD93707.1 - 0.065 13.3 0.4 4.3 7.4 0.0 2.5 2 0 0 2 2 2 0 MbeB-like, N-term conserved region OS-D PF03392.8 EGD93707.1 - 0.09 12.7 0.1 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D DnaJ PF00226.26 EGD93709.1 - 3e-22 78.1 2.5 5.8e-22 77.2 1.2 2.0 2 0 0 2 2 2 1 DnaJ domain Usp PF00582.21 EGD93711.1 - 5.1e-20 72.1 0.6 2.8e-13 50.2 0.2 2.7 2 0 0 2 2 2 2 Universal stress protein family DUF3716 PF12511.3 EGD93712.1 - 2.3e-12 46.3 1.1 3.4e-12 45.7 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Imm41 PF15583.1 EGD93713.1 - 0.099 12.4 0.0 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 41 DUF885 PF05960.6 EGD93713.1 - 0.12 11.5 0.0 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Peptidase_S10 PF00450.17 EGD93715.1 - 1.5e-72 245.0 0.1 4.3e-72 243.5 0.1 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGD93715.1 - 0.033 14.0 0.0 0.12 12.2 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family ATP-synt_ab PF00006.20 EGD93716.1 - 3.5e-61 206.4 0.0 4.7e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGD93716.1 - 1.8e-17 63.8 0.1 3.2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGD93716.1 - 8.1e-11 41.9 0.8 1.8e-10 40.9 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EGD93716.1 - 0.00013 21.7 0.3 0.00029 20.6 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain IncA PF04156.9 EGD93717.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 IncA protein Adeno_E3_CR2 PF02439.10 EGD93717.1 - 0.033 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1517 PF07466.6 EGD93717.1 - 1.1 8.2 3.6 1.4 7.8 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) Notch PF00066.12 EGD93717.1 - 1.1 9.6 10.0 0.097 12.9 2.7 2.3 2 0 0 2 2 2 0 LNR domain Paramecium_SA PF01508.11 EGD93717.1 - 1.7 8.8 11.4 5 7.4 7.9 1.7 1 1 0 1 1 1 0 Paramecium surface antigen domain Trp_syntA PF00290.15 EGD93718.1 - 3.7e-91 304.2 0.0 6.2e-91 303.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EGD93718.1 - 1.8e-43 148.9 1.5 3.6e-43 147.9 1.0 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.21 EGD93722.1 - 7e-24 83.8 0.6 1e-23 83.3 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGD93722.1 - 8.7e-09 36.3 0.2 3.8e-08 34.2 0.0 2.2 1 1 2 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD93722.1 - 2.7e-05 23.8 0.0 5.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EGD93722.1 - 0.023 14.7 0.2 0.056 13.4 0.1 1.7 1 0 0 1 1 1 0 NADH(P)-binding APH PF01636.18 EGD93723.1 - 3.3e-14 53.2 0.0 7.8e-14 51.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGD93723.1 - 0.0026 16.4 0.0 0.31 9.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Kdo PF06293.9 EGD93723.1 - 0.01 14.9 0.0 2 7.4 0.0 2.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGD93723.1 - 0.053 13.0 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EGD93723.1 - 0.092 12.0 0.0 7 5.9 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 EGD93723.1 - 0.1 11.7 0.0 0.63 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain DUF4407 PF14362.1 EGD93724.1 - 0.14 11.1 0.1 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HNH_2 PF13391.1 EGD93725.1 - 4.8e-11 42.2 0.0 1.6e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease GYF PF02213.11 EGD93728.1 - 4e-16 58.3 0.5 2.5e-15 55.7 0.1 2.5 2 0 0 2 2 2 1 GYF domain LMBR1 PF04791.11 EGD93728.1 - 8.5 4.8 3.0 13 4.1 2.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Aminotran_5 PF00266.14 EGD93729.1 - 6.4e-20 71.2 0.0 1.1e-19 70.4 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGD93729.1 - 0.00052 19.0 0.0 0.00074 18.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGD93729.1 - 0.0029 15.9 0.0 0.0041 15.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme zf-RING_2 PF13639.1 EGD93730.1 - 1.2e-14 53.8 20.7 1.2e-14 53.8 6.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGD93730.1 - 1.1e-11 44.1 11.2 6.2e-10 38.5 3.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD93730.1 - 4.9e-08 32.8 7.9 4.9e-08 32.8 5.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD93730.1 - 1.4e-07 31.5 5.0 1.4e-07 31.5 3.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGD93730.1 - 3e-07 30.0 14.8 6.2e-07 29.0 4.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD93730.1 - 3.7e-07 29.6 18.1 6.3e-07 28.9 6.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EGD93730.1 - 1.4e-06 28.1 11.2 0.0001 22.2 3.8 2.5 2 0 0 2 2 2 2 zinc-finger zf-Apc11 PF12861.2 EGD93730.1 - 0.00029 20.6 2.2 0.00029 20.6 1.5 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 EGD93730.1 - 0.00029 20.5 7.0 0.00031 20.3 0.2 2.3 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family Baculo_RING PF05883.6 EGD93730.1 - 0.006 16.4 4.3 0.018 14.8 0.9 2.2 2 0 0 2 2 2 1 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 EGD93730.1 - 0.038 13.5 13.8 0.1 12.1 3.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGD93730.1 - 0.071 12.9 13.2 1.4 8.8 0.5 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.2 EGD93730.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.7 2 1 1 3 3 3 0 Double zinc ribbon DUF1272 PF06906.6 EGD93730.1 - 0.22 11.3 8.9 1 9.2 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Prok-RING_1 PF14446.1 EGD93730.1 - 4 7.2 10.6 14 5.5 0.1 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 EGD93730.1 - 4.2 7.1 10.3 0.56 9.9 4.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger UPF0547 PF10571.4 EGD93730.1 - 4.3 7.1 9.3 12 5.6 0.5 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 PHD PF00628.24 EGD93730.1 - 8.1 6.2 18.3 0.26 11.0 5.1 2.7 2 1 1 3 3 3 0 PHD-finger Fis1_TPR_C PF14853.1 EGD93731.1 - 1.1e-25 89.2 0.3 1.8e-25 88.5 0.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EGD93731.1 - 5.6e-17 60.7 0.0 8.7e-17 60.1 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EGD93731.1 - 0.00078 19.1 1.6 0.0019 18.0 1.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD93731.1 - 0.022 15.4 0.1 0.042 14.5 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGD93731.1 - 2.2 8.0 6.7 0.2 11.3 1.6 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Spc24 PF08286.6 EGD93732.1 - 2.7e-41 139.9 2.4 7.8e-40 135.2 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Streptin-Immun PF11083.3 EGD93732.1 - 0.0023 17.8 2.4 0.0066 16.4 0.2 2.1 1 1 1 2 2 2 1 Lantibiotic streptin immunity protein V_ATPase_I PF01496.14 EGD93732.1 - 0.0038 15.1 2.8 0.0043 14.9 2.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family APG6 PF04111.7 EGD93732.1 - 0.0063 15.6 5.3 0.0081 15.2 3.7 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 MAP65_ASE1 PF03999.7 EGD93732.1 - 0.0089 14.6 4.3 0.012 14.2 3.0 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) WXG100 PF06013.7 EGD93732.1 - 0.014 15.3 2.7 0.1 12.5 0.1 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Prefoldin_2 PF01920.15 EGD93732.1 - 0.06 13.1 6.5 0.37 10.5 0.8 2.3 2 0 0 2 2 2 0 Prefoldin subunit FlxA PF14282.1 EGD93732.1 - 0.079 12.9 3.3 5.9 6.8 0.3 2.2 2 0 0 2 2 2 0 FlxA-like protein FlaC_arch PF05377.6 EGD93732.1 - 0.09 12.6 2.8 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Viral_P18 PF04521.8 EGD93732.1 - 0.13 11.6 7.3 0.32 10.4 0.5 2.3 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF342 PF03961.8 EGD93732.1 - 0.17 10.2 1.9 0.2 10.0 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin PF00804.20 EGD93732.1 - 0.22 11.7 8.9 0.14 12.3 3.9 2.0 1 1 1 2 2 2 0 Syntaxin DASH_Dad3 PF08656.5 EGD93732.1 - 0.22 11.2 3.7 1.9 8.2 0.8 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad3 Laminin_II PF06009.7 EGD93732.1 - 0.49 10.1 5.0 1.1 9.0 3.5 1.6 1 1 0 1 1 1 0 Laminin Domain II DUF972 PF06156.8 EGD93732.1 - 0.72 10.2 5.6 5.5 7.3 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2408 PF10303.4 EGD93732.1 - 0.73 9.9 4.1 1.5 8.9 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) TMF_DNA_bd PF12329.3 EGD93732.1 - 0.87 9.4 9.9 0.7 9.7 2.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF607 PF04678.8 EGD93732.1 - 0.95 9.3 6.8 2.9 7.7 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF607 TBPIP PF07106.8 EGD93732.1 - 1.5 8.3 6.7 1.5 8.3 1.6 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2937 PF11157.3 EGD93732.1 - 1.8 7.8 4.2 1.3 8.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF4140 PF13600.1 EGD93732.1 - 1.9 8.9 9.7 7.3 7.0 1.6 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ribosomal_L29 PF00831.18 EGD93732.1 - 2.2 8.0 7.1 9.7 5.9 0.4 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein DUF3847 PF12958.2 EGD93732.1 - 2.6 7.8 7.6 3.7 7.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) EAP30 PF04157.11 EGD93732.1 - 3.6 6.6 7.7 3.7 6.6 2.2 2.0 1 1 1 2 2 2 0 EAP30/Vps36 family DUF4200 PF13863.1 EGD93732.1 - 4.3 7.3 10.0 38 4.2 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) SlyX PF04102.7 EGD93732.1 - 4.6 7.6 6.2 14 6.1 0.4 2.6 2 1 0 2 2 2 0 SlyX Mnd1 PF03962.10 EGD93732.1 - 6.5 6.3 7.8 22 4.6 5.5 1.7 1 1 0 1 1 1 0 Mnd1 family DUF3431 PF11913.3 EGD93733.1 - 5.8e-84 281.0 0.0 7.5e-84 280.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF2034 PF10356.4 EGD93734.1 - 1.3e-37 128.7 0.0 5.7e-35 120.1 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EGD93734.1 - 2e-08 34.0 0.0 3.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.3 EGD93735.1 - 8.4e-53 178.2 17.8 2.9e-52 176.4 12.4 1.7 1 1 0 1 1 1 1 Subunit 21 of Mediator complex PAT1 PF09770.4 EGD93735.1 - 0.021 13.1 14.6 0.024 12.9 10.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1319 PF07028.6 EGD93735.1 - 0.05 13.8 0.6 0.087 13.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Spore_III_AB PF09548.5 EGD93735.1 - 0.052 13.3 0.5 0.052 13.3 0.3 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Med9 PF07544.8 EGD93735.1 - 0.067 12.9 7.1 0.044 13.5 2.8 2.3 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SPX PF03105.14 EGD93735.1 - 0.079 12.7 1.4 0.13 12.0 1.0 1.3 1 0 0 1 1 1 0 SPX domain RBD-FIP PF09457.5 EGD93735.1 - 0.24 11.2 4.5 0.12 12.1 1.1 2.1 2 0 0 2 2 2 0 FIP domain TFIIA PF03153.8 EGD93735.1 - 0.26 11.1 8.0 0.3 10.9 5.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EGD93735.1 - 0.52 9.6 9.7 0.62 9.4 6.7 1.1 1 0 0 1 1 1 0 Vta1 like Striatin PF08232.7 EGD93735.1 - 1.3 9.3 8.2 9.5 6.5 0.1 2.2 2 0 0 2 2 2 0 Striatin family SNF2_N PF00176.18 EGD93736.1 - 5.1e-63 212.6 0.1 7.4e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD93736.1 - 2.7e-08 33.5 0.1 9.8e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF896 PF05979.7 EGD93736.1 - 0.81 9.3 8.6 10 5.8 2.9 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) zf-RING_5 PF14634.1 EGD93736.1 - 2.2 8.0 4.1 4.3 7.1 2.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PI3_PI4_kinase PF00454.22 EGD93737.1 - 2.5e-39 135.1 0.0 4.6e-39 134.2 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.22 EGD93738.1 - 1.3e-15 56.4 2.4 2.5e-15 55.4 1.6 1.5 1 0 0 1 1 1 1 GATA zinc finger DivIVA PF05103.8 EGD93738.1 - 0.00065 19.7 2.7 0.0013 18.8 1.9 1.4 1 0 0 1 1 1 1 DivIVA protein TF_Zn_Ribbon PF08271.7 EGD93738.1 - 0.035 13.4 0.3 0.064 12.5 0.2 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Auto_anti-p27 PF06677.7 EGD93738.1 - 0.042 13.6 0.2 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF3461 PF11944.3 EGD93738.1 - 0.066 13.0 0.3 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) ArfGap PF01412.13 EGD93738.1 - 0.091 12.5 0.2 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.12 EGD93738.1 - 0.13 11.8 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain found in IF2B/IF5 DUF904 PF06005.7 EGD93738.1 - 0.19 12.0 4.0 0.34 11.2 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 EGD93738.1 - 0.3 10.6 6.1 0.48 9.9 4.2 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EGD93738.1 - 2.2 7.2 6.6 3.2 6.7 4.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AATF-Che1 PF13339.1 EGD93738.1 - 6.2 6.9 8.3 1.5 9.0 3.0 2.0 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Nodulin-like PF06813.8 EGD93739.1 - 1.5e-20 73.5 6.5 1.5e-20 73.5 4.5 1.9 2 1 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 EGD93739.1 - 4.3e-16 58.5 31.2 9.7e-13 47.5 7.2 2.6 2 1 0 3 3 3 2 Major Facilitator Superfamily Serinc PF03348.10 EGD93740.1 - 4e-150 500.2 15.2 2.6e-149 497.5 10.5 1.8 1 1 0 1 1 1 1 Serine incorporator (Serinc) FA_desaturase PF00487.19 EGD93740.1 - 0.0013 18.1 12.0 0.15 11.4 4.8 3.0 2 1 1 3 3 3 2 Fatty acid desaturase ATG27 PF09451.5 EGD93740.1 - 3.2 6.9 4.8 0.61 9.2 0.1 2.0 2 1 0 2 2 2 0 Autophagy-related protein 27 DNA_mis_repair PF01119.14 EGD93741.1 - 4.8e-21 74.4 0.0 3.3e-19 68.4 0.0 2.6 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EGD93741.1 - 8.3e-19 67.6 1.8 2.2e-15 56.5 1.1 3.0 3 0 0 3 3 3 2 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EGD93741.1 - 3.5e-06 26.7 0.0 8.8e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGD93741.1 - 0.00012 21.7 0.0 0.00028 20.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GCN5L1 PF06320.8 EGD93742.1 - 4.1e-10 39.5 1.2 5e-10 39.2 0.8 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) CagE_TrbE_VirB PF03135.9 EGD93742.1 - 0.012 15.4 0.3 0.012 15.4 0.2 1.1 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system DUF3552 PF12072.3 EGD93742.1 - 0.02 14.1 1.9 0.021 14.0 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Laminin_II PF06009.7 EGD93742.1 - 0.055 13.2 1.3 0.064 13.0 0.9 1.3 1 0 0 1 1 1 0 Laminin Domain II Nsp1_C PF05064.8 EGD93742.1 - 0.055 13.1 2.7 0.079 12.5 1.6 1.5 1 1 0 1 1 1 0 Nsp1-like C-terminal region GAS PF13851.1 EGD93742.1 - 0.062 12.4 1.7 0.073 12.2 1.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PilJ PF13675.1 EGD93742.1 - 0.066 13.5 1.7 0.095 13.0 1.2 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cellsynth_D PF03500.8 EGD93742.1 - 0.13 11.9 0.1 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Cellulose synthase subunit D DivIC PF04977.10 EGD93742.1 - 0.21 11.0 2.3 0.39 10.2 1.6 1.4 1 0 0 1 1 1 0 Septum formation initiator CHASE3 PF05227.8 EGD93742.1 - 0.26 10.9 5.0 0.89 9.2 2.6 2.2 1 1 0 1 1 1 0 CHASE3 domain DUF848 PF05852.6 EGD93742.1 - 0.44 10.3 4.4 0.63 9.8 3.0 1.3 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Syntaxin-6_N PF09177.6 EGD93742.1 - 0.59 10.5 4.6 6.1 7.3 1.9 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Sugar_tr PF00083.19 EGD93743.1 - 2.2e-81 273.7 28.8 2.5e-81 273.5 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD93743.1 - 7.6e-24 84.0 26.9 1.2e-22 80.1 17.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Nucleoplasmin PF03066.10 EGD93745.1 - 0.055 12.9 0.8 0.088 12.3 0.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin FTA2 PF13095.1 EGD93746.1 - 1.4e-69 233.8 0.0 1.7e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 WD40 PF00400.27 EGD93747.1 - 3.4e-24 83.8 18.3 8.7e-06 25.4 0.0 9.0 9 0 0 9 9 9 6 WD domain, G-beta repeat DUF3010 PF11215.3 EGD93747.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) SPO22 PF08631.5 EGD93749.1 - 6.7e-06 25.3 0.3 1.5e-05 24.2 0.2 1.6 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like Zn_clus PF00172.13 EGD93750.1 - 3.7e-06 26.7 10.6 6.8e-06 25.8 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SnoaL_2 PF12680.2 EGD93750.1 - 0.018 15.4 0.0 0.044 14.2 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain CENP-Q PF13094.1 EGD93751.1 - 1.3e-57 194.2 6.2 2.2e-57 193.5 4.3 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit BRE1 PF08647.6 EGD93751.1 - 0.016 15.1 7.0 0.048 13.6 4.8 1.8 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF904 PF06005.7 EGD93751.1 - 0.018 15.2 9.4 0.018 15.2 6.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF904) GAS PF13851.1 EGD93751.1 - 0.029 13.5 6.9 0.28 10.3 4.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 EGD93751.1 - 0.12 12.0 9.0 0.23 11.2 5.5 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EGD93751.1 - 0.14 11.7 5.5 0.17 11.4 3.8 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EGD93751.1 - 0.21 9.4 2.9 0.28 8.9 2.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3373 PF11853.3 EGD93751.1 - 0.31 9.5 1.3 0.38 9.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF2560 PF10834.3 EGD93751.1 - 0.31 11.0 2.7 5.6 7.0 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2560) APG6 PF04111.7 EGD93751.1 - 0.35 9.8 4.6 0.45 9.5 3.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_CLD_2 PF14197.1 EGD93751.1 - 0.67 9.9 17.8 4 7.4 3.7 3.6 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 DUF4337 PF14235.1 EGD93751.1 - 8 6.2 7.9 10 5.9 4.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) APH PF01636.18 EGD93752.1 - 2.7e-20 73.1 0.1 7.8e-19 68.3 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGD93752.1 - 9.6e-05 21.1 0.1 0.038 12.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.15 EGD93752.1 - 0.00013 21.2 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.20 EGD93752.1 - 0.0048 16.0 0.0 2.4 7.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Fructosamin_kin PF03881.9 EGD93752.1 - 0.012 14.6 0.0 0.34 9.8 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Ser_hydrolase PF06821.8 EGD93753.1 - 0.0049 16.4 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase DUF4342 PF14242.1 EGD93753.1 - 0.094 12.5 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) HLH PF00010.21 EGD93754.1 - 4.3e-05 23.1 0.0 0.00012 21.6 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Sporozoite_P67 PF05642.6 EGD93754.1 - 2.2 6.0 9.7 3.5 5.3 6.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2217 PF10265.4 EGD93754.1 - 7.8 5.1 7.2 15 4.1 5.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Cation_ATPase_C PF00689.16 EGD93755.1 - 0.0041 16.6 0.1 0.0081 15.7 0.1 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Semialdhyde_dhC PF02774.13 EGD93756.1 - 1.9e-37 128.9 0.0 2.7e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EGD93756.1 - 2.5e-30 105.2 0.0 9.8e-30 103.3 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EGD93756.1 - 0.0012 19.3 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EGD93756.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Peptidase_M35 PF02102.10 EGD93757.1 - 4.4e-106 354.5 4.6 5.1e-106 354.3 3.2 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGD93757.1 - 4.9e-05 23.8 0.0 9.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EGD93757.1 - 0.00015 21.2 0.3 0.0013 18.2 0.2 2.0 1 1 0 1 1 1 1 Putative peptidase family Polysacc_deac_1 PF01522.16 EGD93759.1 - 7.5e-28 96.6 0.0 1.4e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGD93759.1 - 0.026 13.4 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF1444 PF07285.6 EGD93760.1 - 0.036 13.3 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) CtaG_Cox11 PF04442.9 EGD93761.1 - 1.2e-59 200.4 0.1 1.6e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 BRCA2 PF00634.13 EGD93761.1 - 0.11 11.7 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 BRCA2 repeat Rep_fac_C PF08542.6 EGD93762.1 - 3.4e-21 75.0 0.0 9.6e-21 73.5 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGD93762.1 - 2.1e-11 43.7 0.0 3.8e-11 42.9 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EGD93762.1 - 8.8e-07 29.1 0.1 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD93762.1 - 1.6e-05 25.0 0.3 7.8e-05 22.8 0.2 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD93762.1 - 0.00076 19.5 0.6 0.021 14.8 0.4 2.3 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EGD93762.1 - 0.013 15.5 0.2 0.39 10.7 0.2 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EGD93762.1 - 0.017 15.4 0.1 0.037 14.3 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 EGD93762.1 - 0.017 14.5 0.2 0.95 8.8 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain SNF2_N PF00176.18 EGD93762.1 - 0.021 13.5 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_33 PF13671.1 EGD93762.1 - 0.026 14.3 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T4SS-DNA_transf PF02534.9 EGD93762.1 - 0.059 11.9 0.0 0.098 11.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer TK PF00265.13 EGD93762.1 - 0.081 12.4 0.6 0.37 10.3 0.4 1.9 1 1 0 1 1 1 0 Thymidine kinase Arch_ATPase PF01637.13 EGD93762.1 - 0.095 12.3 0.1 0.27 10.8 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase Methyltransf_31 PF13847.1 EGD93762.1 - 0.11 12.0 0.1 0.8 9.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_L16 PF00252.13 EGD93763.1 - 5.2e-28 97.4 0.1 8e-28 96.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.7 EGD93764.1 - 1.5e-56 190.4 0.3 9.2e-56 187.9 0.0 2.2 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EGD93764.1 - 1.1e-12 47.8 0.0 3.6e-12 46.2 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EGD93764.1 - 3.3e-09 37.0 1.3 4.7e-09 36.5 0.1 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD93764.1 - 1.4e-05 25.2 0.0 4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD93764.1 - 3.6e-05 24.5 0.3 0.00016 22.4 0.0 2.4 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.10 EGD93764.1 - 0.00081 18.1 0.0 0.0024 16.6 0.0 1.7 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EGD93764.1 - 0.0013 18.4 0.1 0.0036 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EGD93764.1 - 0.0023 17.0 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGD93764.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD93764.1 - 0.0076 16.2 0.0 0.034 14.1 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EGD93764.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EGD93764.1 - 0.029 13.8 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain PTCB-BRCT PF12738.2 EGD93764.1 - 0.04 13.7 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 twin BRCT domain AAA_18 PF13238.1 EGD93764.1 - 0.053 13.8 0.1 0.053 13.8 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 EGD93764.1 - 0.062 13.0 0.1 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EGD93764.1 - 0.066 12.8 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain NAD_binding_8 PF13450.1 EGD93765.1 - 3.4e-13 49.4 0.0 1.2e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGD93765.1 - 2.1e-06 27.1 0.6 9.7e-05 21.6 0.4 2.7 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EGD93765.1 - 0.001 18.0 0.0 0.064 12.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGD93765.1 - 0.002 17.8 0.0 0.065 12.9 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EGD93765.1 - 0.034 12.7 0.0 0.055 12.0 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.14 EGD93765.1 - 0.053 12.5 0.0 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EGD93765.1 - 0.061 13.7 0.0 8.4 6.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD93765.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Septin PF00735.13 EGD93767.1 - 2.4e-121 404.1 0.1 2.4e-121 404.1 0.1 1.7 2 0 0 2 2 2 1 Septin DUF258 PF03193.11 EGD93767.1 - 4e-06 26.1 0.1 2.8e-05 23.3 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGD93767.1 - 5.3e-06 26.3 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGD93767.1 - 0.00032 21.0 3.4 0.065 13.5 0.0 2.9 2 1 1 3 3 3 1 ABC transporter AAA_16 PF13191.1 EGD93767.1 - 0.0022 17.9 0.3 0.025 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 EGD93767.1 - 0.0026 17.2 0.4 0.16 11.3 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGD93767.1 - 0.0028 17.7 0.0 0.024 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EGD93767.1 - 0.0066 15.9 1.3 0.034 13.5 0.8 2.2 1 1 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 EGD93767.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 EGD93767.1 - 0.016 14.6 0.0 0.063 12.6 0.0 2.0 1 1 0 1 1 1 0 Ras family ATP_bind_1 PF03029.12 EGD93767.1 - 0.025 14.1 0.3 1.8 8.0 0.0 2.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 EGD93767.1 - 0.031 13.6 0.0 0.095 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EGD93767.1 - 0.049 14.1 0.4 0.23 11.9 0.0 2.3 3 0 0 3 3 2 0 Miro-like protein DUF2937 PF11157.3 EGD93767.1 - 0.056 12.7 4.1 0.12 11.7 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) FtsK_SpoIIIE PF01580.13 EGD93767.1 - 0.067 12.6 1.5 0.15 11.5 0.0 2.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family Strep_SA_rep PF06696.6 EGD93767.1 - 0.17 11.6 1.4 0.39 10.5 1.0 1.7 1 0 0 1 1 1 0 Streptococcal surface antigen repeat YlqD PF11068.3 EGD93767.1 - 0.35 10.9 11.7 0.76 9.8 8.1 1.5 1 0 0 1 1 1 0 YlqD protein Dynamin_N PF00350.18 EGD93767.1 - 0.4 10.4 7.4 9.3 6.0 0.0 3.6 3 1 0 3 3 3 0 Dynamin family Exonuc_VII_L PF02601.10 EGD93767.1 - 0.51 9.4 12.3 0.57 9.3 7.9 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.6 EGD93767.1 - 0.52 9.5 8.2 0.81 8.8 5.7 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase UPF0121 PF03661.8 EGD93769.1 - 3.2e-10 39.6 0.6 4.3e-10 39.2 0.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) 7TM_GPCR_Str PF10326.4 EGD93769.1 - 0.02 13.9 1.6 0.073 12.1 0.2 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str Mito_carr PF00153.22 EGD93770.1 - 2.3e-41 139.4 0.1 9.7e-20 70.0 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein CHCH PF06747.8 EGD93772.1 - 1.1e-06 28.4 5.3 1.8e-06 27.6 3.6 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EGD93772.1 - 0.027 14.6 1.5 0.062 13.4 1.0 1.7 1 0 0 1 1 1 0 GCK domain TPK_catalytic PF04263.11 EGD93773.1 - 7.5e-22 77.2 0.0 8.6e-21 73.7 0.0 2.0 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EGD93773.1 - 2.2e-18 65.7 0.1 3.7e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain HEAT PF02985.17 EGD93774.1 - 0.08 13.0 0.0 3 8.1 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat Upf2 PF04050.9 EGD93775.1 - 1.5e-57 194.1 21.0 1.5e-57 194.1 14.6 2.6 2 0 0 2 2 2 1 Up-frameshift suppressor 2 MIF4G PF02854.14 EGD93775.1 - 3.6e-56 189.8 0.0 2.3e-26 92.4 0.0 4.3 4 1 0 4 4 4 3 MIF4G domain CytoC_RC PF02276.13 EGD93775.1 - 0.035 13.2 0.1 0.55 9.2 0.0 2.2 2 0 0 2 2 2 0 Photosynthetic reaction centre cytochrome C subunit DUF1515 PF07439.6 EGD93776.1 - 0.0083 15.9 0.3 0.039 13.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1515) DUF4201 PF13870.1 EGD93776.1 - 0.043 13.2 0.4 0.077 12.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.4 EGD93776.1 - 0.048 13.5 1.0 0.19 11.5 0.5 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pyr_redox_3 PF13738.1 EGD93777.1 - 5.1e-28 98.5 0.0 7.6e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGD93777.1 - 2.3e-18 65.7 0.1 3e-17 62.0 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGD93777.1 - 5e-09 36.0 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EGD93777.1 - 1.1e-08 34.4 0.1 1.7e-06 27.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGD93777.1 - 4.3e-06 26.7 0.0 3.9e-05 23.6 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD93777.1 - 0.00016 20.7 0.0 0.00067 18.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EGD93777.1 - 0.0021 18.1 0.1 0.4 10.7 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EGD93777.1 - 0.0034 17.1 0.0 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EGD93777.1 - 0.0047 16.0 0.3 0.0087 15.1 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EGD93777.1 - 0.018 13.9 0.3 0.026 13.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 EGD93777.1 - 0.17 12.1 0.0 5.2 7.3 0.0 2.4 3 0 0 3 3 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 EGD93777.1 - 0.45 8.9 1.4 0.77 8.1 1.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_18 PF00704.23 EGD93778.1 - 2.2e-93 313.4 0.6 2.6e-93 313.2 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EGD93778.1 - 2.3e-12 46.5 0.0 4.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain Glyco_transf_8 PF01501.15 EGD93779.1 - 1.9e-27 96.1 0.0 2.3e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EGD93779.1 - 0.054 12.8 0.3 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 Mannosyltransferase putative APH PF01636.18 EGD93780.1 - 1.4e-11 44.5 0.0 2.7e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family SUN PF03856.8 EGD93783.1 - 3.9e-93 311.3 6.2 5.2e-93 310.9 4.3 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Fer4_10 PF13237.1 EGD93783.1 - 5.7 6.8 6.8 0.24 11.2 0.4 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Ribosomal_L1 PF00687.16 EGD93784.1 - 2.7e-50 170.7 0.1 2.7e-50 170.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family DUF2228 PF10228.4 EGD93784.1 - 0.84 9.1 3.5 2 7.8 2.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) ETF PF01012.16 EGD93785.1 - 1.2e-37 129.1 0.6 2.3e-37 128.2 0.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EGD93785.1 - 1.2e-34 117.7 0.1 2.9e-34 116.5 0.1 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Flagellin_IN PF07196.8 EGD93785.1 - 9 6.3 7.4 7.3 6.6 0.2 2.7 3 0 0 3 3 3 0 Flagellin hook IN motif Kdo PF06293.9 EGD93787.1 - 3.8e-06 26.1 0.0 8.4e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD93787.1 - 9.1e-05 22.2 0.2 9.1e-05 22.2 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGD93787.1 - 0.00014 21.1 0.0 0.00052 19.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.15 EGD93787.1 - 0.013 15.0 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EGD93787.1 - 0.042 13.1 0.0 0.093 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EGD93787.1 - 0.081 12.2 0.0 0.26 10.6 0.0 1.8 1 0 0 1 1 1 0 RIO1 family AAA PF00004.24 EGD93790.1 - 1e-11 45.1 0.0 1.9e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGD93790.1 - 5.5e-06 26.1 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGD93790.1 - 1.1e-05 24.6 0.0 2.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGD93790.1 - 1.3e-05 25.3 0.0 2.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EGD93790.1 - 1.9e-05 23.5 0.0 2.8e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EGD93790.1 - 5.4e-05 22.8 0.4 0.0002 21.0 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EGD93790.1 - 0.00012 22.0 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD93790.1 - 0.00042 21.1 0.1 0.0021 18.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGD93790.1 - 0.00094 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EGD93790.1 - 0.0028 17.5 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD93790.1 - 0.0059 16.6 0.0 0.028 14.4 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EGD93790.1 - 0.029 14.6 0.1 0.061 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGD93790.1 - 0.034 13.8 0.1 0.073 12.7 0.1 1.6 1 0 0 1 1 1 0 NTPase DUF1776 PF08643.5 EGD93790.1 - 0.045 12.8 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF258 PF03193.11 EGD93790.1 - 0.059 12.5 1.7 0.06 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 BicD PF09730.4 EGD93791.1 - 0.00019 19.9 2.2 0.00032 19.1 1.5 1.3 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Lebercilin PF15619.1 EGD93791.1 - 0.00044 19.7 1.3 0.16 11.3 0.0 3.0 1 1 1 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.16 EGD93791.1 - 0.00069 19.1 4.9 0.0012 18.4 3.4 1.3 1 0 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.6 EGD93791.1 - 0.0048 15.6 4.9 0.0091 14.6 3.4 1.4 1 1 0 1 1 1 1 Spc7 kinetochore protein Mating_N PF12731.2 EGD93791.1 - 0.021 14.6 2.3 0.06 13.2 0.5 2.4 1 1 1 2 2 2 0 Mating-type protein beta 1 Snapin_Pallidin PF14712.1 EGD93791.1 - 0.071 13.4 2.1 1.1 9.5 0.3 3.1 2 1 1 3 3 3 0 Snapin/Pallidin TMF_DNA_bd PF12329.3 EGD93791.1 - 0.081 12.7 4.4 4.3 7.2 0.2 3.3 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Matrilin_ccoil PF10393.4 EGD93791.1 - 0.09 12.1 4.4 12 5.3 0.0 4.2 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Tropomyosin PF00261.15 EGD93791.1 - 0.1 11.6 6.0 0.17 10.9 0.8 2.7 1 1 1 2 2 2 0 Tropomyosin Reo_sigmaC PF04582.7 EGD93791.1 - 0.13 11.4 9.7 0.22 10.6 4.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Cas_Csx9 PF09658.5 EGD93791.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) Phage_Mu_Gam PF07352.7 EGD93791.1 - 0.22 11.0 3.6 0.14 11.6 0.8 1.8 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Baculo_PEP_C PF04513.7 EGD93791.1 - 0.28 10.9 11.3 2.2 8.1 0.3 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 EGD93791.1 - 0.33 10.8 3.8 4.4 7.1 0.2 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Bacillus_HBL PF05791.6 EGD93791.1 - 0.64 9.3 7.2 1 8.7 2.5 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3533 PF12051.3 EGD93791.1 - 1.2 7.7 5.1 7.1 5.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) DUF4404 PF14357.1 EGD93791.1 - 3.1 8.2 7.1 4.9 7.6 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) SWIRM PF04433.12 EGD93792.1 - 1.9e-33 114.4 0.0 4.4e-33 113.2 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EGD93792.1 - 3.2e-07 30.2 0.1 6.1e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD93792.1 - 2.5e-05 24.2 0.1 6.7e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EGD93792.1 - 0.028 13.9 2.9 0.028 13.9 0.0 2.0 2 0 0 2 2 2 0 Zinc finger, ZZ type Vfa1 PF08432.5 EGD93792.1 - 3.7 7.5 15.5 2 8.4 3.6 3.2 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Myb_DNA-binding PF00249.26 EGD93793.1 - 0.005 16.8 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2457 PF10446.4 EGD93793.1 - 0.4 9.3 22.8 0.7 8.5 15.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Astro_capsid PF03115.9 EGD93793.1 - 0.63 8.2 9.2 1.1 7.4 6.3 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Pkinase_Tyr PF07714.12 EGD93794.1 - 3.9e-09 35.9 0.0 6.2e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD93794.1 - 5.8e-08 32.7 0.0 7.7e-06 25.8 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGD93794.1 - 5.2e-07 29.0 0.0 1.1e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EGD93794.1 - 0.0095 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGD93794.1 - 0.056 12.2 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EGD93794.1 - 0.12 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EGD93794.1 - 0.17 11.4 0.0 0.5 9.8 0.0 1.6 1 1 1 2 2 2 0 Choline/ethanolamine kinase ResIII PF04851.10 EGD93795.1 - 4.2e-23 82.1 0.0 9.5e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGD93795.1 - 3.4e-13 49.2 0.0 1.1e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD93795.1 - 1.8e-12 47.0 0.0 3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EGD93795.1 - 3.8e-05 22.8 0.0 6.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EGD93795.1 - 0.057 12.7 0.4 0.98 8.6 0.0 2.2 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain SNF2_N PF00176.18 EGD93795.1 - 0.074 11.8 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ank_2 PF12796.2 EGD93796.1 - 9.6e-16 57.9 0.0 1.6e-08 34.7 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGD93796.1 - 5.6e-15 54.3 0.6 0.00016 21.2 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EGD93796.1 - 2e-08 34.4 0.2 0.012 16.1 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD93796.1 - 1.6e-07 30.8 0.0 0.56 10.6 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGD93796.1 - 1.7e-05 24.8 0.1 6.1 7.2 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Glyco_transf_90 PF05686.7 EGD93798.1 - 6e-28 97.6 1.2 8.1e-28 97.2 0.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EGD93798.1 - 0.0031 17.7 0.1 0.0074 16.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 PGAP1 PF07819.8 EGD93799.1 - 3.3e-80 268.9 0.0 5.4e-80 268.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGD93799.1 - 2.4e-06 27.3 0.1 1.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD93799.1 - 2.3e-05 24.3 0.6 4.7e-05 23.3 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD93799.1 - 0.0004 20.0 0.0 0.00079 19.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EGD93799.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase LCAT PF02450.10 EGD93799.1 - 0.009 15.0 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EGD93799.1 - 0.015 14.5 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF915 PF06028.6 EGD93799.1 - 0.32 10.0 0.0 0.61 9.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_M28 PF04389.12 EGD93800.1 - 6.5e-25 87.9 0.1 1.7e-24 86.5 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGD93800.1 - 3.9e-06 26.5 0.0 5.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EGD93800.1 - 0.00019 20.2 0.0 0.0005 18.9 0.0 1.8 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase 4_1_CTD PF05902.8 EGD93800.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) fn3 PF00041.16 EGD93800.1 - 0.015 15.3 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain Nicastrin PF05450.10 EGD93800.1 - 0.075 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Nicastrin HlyIII PF03006.15 EGD93801.1 - 1.7e-10 40.6 4.8 9.7e-08 31.6 0.8 2.2 1 1 1 2 2 2 2 Haemolysin-III related NAD_binding_10 PF13460.1 EGD93803.1 - 1e-08 35.3 0.0 4.7e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGD93803.1 - 7.5e-05 22.0 0.2 0.00018 20.8 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 EGD93803.1 - 0.024 14.3 0.1 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 KR domain APG17 PF04108.7 EGD93806.1 - 1.1e-114 383.4 0.0 1.3e-114 383.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Tweety PF04906.8 EGD93806.1 - 0.017 13.5 1.1 0.31 9.4 0.0 2.5 3 0 0 3 3 3 0 Tweety WD40 PF00400.27 EGD93807.1 - 3.4e-63 207.4 19.0 4e-11 42.3 0.3 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EGD93807.1 - 1.5e-15 56.6 0.4 3.3e-15 55.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD93807.1 - 1.6e-11 43.5 0.4 3.7e-11 42.3 0.1 1.8 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 EGD93807.1 - 5.5e-10 37.9 11.7 0.00024 19.3 0.7 4.9 2 2 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGD93807.1 - 0.024 13.3 2.5 2.1 6.9 0.1 2.8 1 1 2 3 3 3 0 Nup133 N terminal like PRANC PF09372.5 EGD93807.1 - 0.041 13.8 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 PRANC domain DUF3186 PF11382.3 EGD93812.1 - 0.1 11.7 0.3 0.18 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) RIO1 PF01163.17 EGD93813.1 - 1.2e-72 243.2 0.1 1.2e-72 243.2 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EGD93813.1 - 1.6e-06 28.0 0.3 0.00057 19.6 0.1 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGD93813.1 - 0.00021 20.4 0.3 0.0024 16.9 0.2 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3464 PF11947.3 EGD93813.1 - 0.044 13.2 0.9 0.12 11.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Choline_kinase PF01633.15 EGD93813.1 - 0.05 13.1 1.0 0.099 12.2 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase SMC_N PF02463.14 EGD93814.1 - 3e-64 216.2 27.4 6.7e-64 215.1 19.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGD93814.1 - 2e-33 114.9 0.3 2.4e-32 111.4 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGD93814.1 - 2.7e-18 66.9 1.6 2.2e-09 37.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EGD93814.1 - 7.2e-13 49.3 27.3 7.2e-13 49.3 18.9 6.5 2 2 2 4 4 4 1 AAA domain AAA_15 PF13175.1 EGD93814.1 - 8.2e-11 41.5 24.5 4.2e-07 29.3 9.0 3.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EGD93814.1 - 0.00032 20.1 0.0 0.00073 19.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EGD93814.1 - 0.048 12.1 87.7 0.046 12.1 17.8 5.8 3 2 3 6 6 6 0 AAA domain Reo_sigmaC PF04582.7 EGD93814.1 - 0.074 12.2 24.3 0.73 8.9 2.3 4.8 3 1 1 4 4 4 0 Reovirus sigma C capsid protein FtsK_SpoIIIE PF01580.13 EGD93814.1 - 0.26 10.7 0.0 0.26 10.7 0.0 4.3 5 1 1 6 6 6 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EGD93814.1 - 0.39 11.0 0.0 0.39 11.0 0.0 6.1 4 2 0 4 4 4 0 ABC transporter DUF3605 PF12239.3 EGD93815.1 - 2.1e-58 196.6 0.4 2.5e-58 196.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Dfp1_Him1_M PF08630.5 EGD93815.1 - 0.043 13.5 0.0 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region FAD_binding_6 PF00970.19 EGD93816.1 - 8.6e-29 99.5 0.0 1.4e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGD93816.1 - 3.5e-27 95.1 0.0 6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EGD93816.1 - 1.5e-05 24.9 0.0 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EGD93816.1 - 0.0025 17.7 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF4176 PF13780.1 EGD93816.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) WD40 PF00400.27 EGD93817.1 - 1e-16 60.0 20.6 2.7e-06 27.0 0.6 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat tRNA-synt_1d PF00750.14 EGD93818.1 - 2.8e-77 259.9 9.2 8.3e-42 143.2 5.2 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EGD93818.1 - 7.4e-29 100.1 0.0 1.9e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EGD93818.1 - 3.5e-05 24.2 0.9 0.00012 22.5 0.0 2.3 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Snapin_Pallidin PF14712.1 EGD93818.1 - 0.047 13.9 0.8 0.23 11.8 0.1 2.2 2 0 0 2 2 2 0 Snapin/Pallidin Kelch_4 PF13418.1 EGD93820.1 - 5.1e-07 29.3 3.9 0.0064 16.2 0.1 4.8 4 1 0 4 4 4 2 Galactose oxidase, central domain SKG6 PF08693.5 EGD93820.1 - 7.1e-05 22.0 2.2 0.00014 21.1 1.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_3 PF13415.1 EGD93820.1 - 0.00013 22.0 3.0 3.1 8.0 0.1 4.3 3 0 0 3 3 3 2 Galactose oxidase, central domain DUF3246 PF11596.3 EGD93820.1 - 0.00033 20.0 0.7 0.00074 18.8 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Mid2 PF04478.7 EGD93820.1 - 0.002 17.5 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Kelch_2 PF07646.10 EGD93820.1 - 0.0028 17.3 1.2 0.62 9.9 0.0 4.0 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 EGD93820.1 - 0.0034 17.2 0.0 0.11 12.4 0.0 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 EGD93820.1 - 0.031 14.4 2.1 1.3 9.2 0.0 4.1 5 0 0 5 5 5 0 Kelch motif BPL_LplA_LipB PF03099.14 EGD93821.1 - 2.9e-10 40.2 0.0 8.5e-10 38.7 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 EGD93822.1 - 6.8e-132 439.1 0.0 7.9e-132 438.9 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Ima1_N PF09779.4 EGD93823.1 - 5.4e-43 146.6 7.5 1.3e-42 145.4 5.2 1.7 1 0 0 1 1 1 1 Ima1 N-terminal domain Zn_Tnp_IS1595 PF12760.2 EGD93823.1 - 3.6 7.4 10.7 0.38 10.6 2.8 2.6 3 0 0 3 3 3 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EGD93823.1 - 7.7 6.2 7.1 0.49 10.0 0.6 2.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DZR PF12773.2 EGD93823.1 - 9.3 6.1 7.3 19 5.1 0.4 2.6 2 1 0 2 2 2 0 Double zinc ribbon Alg14 PF08660.6 EGD93824.1 - 4.7e-40 137.3 0.0 6.2e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF3040 PF11239.3 EGD93825.1 - 0.035 14.1 0.5 0.085 12.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) PNK3P PF08645.6 EGD93827.1 - 1.4e-55 187.0 0.2 2.4e-55 186.3 0.0 1.5 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EGD93827.1 - 2e-30 105.5 0.0 7.8e-30 103.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGD93827.1 - 6.2e-09 35.4 1.6 2.1e-05 23.8 0.0 2.4 1 1 1 2 2 2 2 Chromatin associated protein KTI12 HAD_2 PF13419.1 EGD93827.1 - 0.0033 17.6 0.1 5.4 7.1 0.0 2.8 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.7 EGD93827.1 - 0.0072 15.4 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EGD93827.1 - 0.017 14.6 0.1 0.14 11.6 0.0 2.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EGD93827.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain CgtA PF06306.6 EGD93827.1 - 0.13 11.4 0.1 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) AAA_17 PF13207.1 EGD93827.1 - 0.2 12.4 0.6 0.66 10.8 0.2 2.1 2 1 0 2 2 2 0 AAA domain Med18 PF09637.5 EGD93828.1 - 3.7e-35 121.6 0.0 3.3e-17 62.8 0.0 2.0 1 1 1 2 2 2 2 Med18 protein DUF2638 PF10937.3 EGD93829.1 - 9.6e-41 139.3 0.3 1.1e-40 139.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF647 PF04884.9 EGD93830.1 - 5.1e-67 225.6 0.3 7.7e-67 225.1 0.2 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis RGS PF00615.14 EGD93833.1 - 5.5e-12 45.8 0.0 8.7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.20 EGD93835.1 - 8.1e-36 123.4 0.0 1e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93835.1 - 2.3e-14 53.1 0.0 3.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD93835.1 - 0.01 15.5 0.0 0.42 10.2 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family AICARFT_IMPCHas PF01808.13 EGD93836.1 - 1.8e-104 349.2 0.0 2.8e-104 348.5 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EGD93836.1 - 5e-25 87.2 0.0 9.4e-25 86.3 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Rtt106 PF08512.7 EGD93837.1 - 5.7e-28 96.7 0.0 1.3e-27 95.5 0.0 1.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like KOW PF00467.24 EGD93838.1 - 3.5e-08 32.8 0.6 7.1e-08 31.8 0.4 1.5 1 0 0 1 1 1 1 KOW motif Ras PF00071.17 EGD93839.1 - 3.5e-44 150.0 0.0 4.4e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD93839.1 - 1.1e-14 54.9 0.0 1.6e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD93839.1 - 2.2e-05 23.7 0.0 3.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGD93839.1 - 0.0045 16.2 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGD93839.1 - 0.041 13.0 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Podoplanin PF05808.6 EGD93840.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Podoplanin MGC-24 PF05283.6 EGD93840.1 - 0.0053 16.5 2.0 0.0053 16.5 1.4 1.7 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24) Pex14_N PF04695.8 EGD93840.1 - 0.017 15.1 0.3 0.017 15.1 0.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Syndecan PF01034.15 EGD93840.1 - 0.063 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Rab5ip PF07019.7 EGD93840.1 - 0.082 13.0 0.2 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) DUF4131 PF13567.1 EGD93840.1 - 0.096 12.0 0.1 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SOG2 PF10428.4 EGD93840.1 - 0.15 10.6 6.3 0.19 10.3 4.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein VSP PF03302.8 EGD93840.1 - 0.16 10.5 0.5 0.27 9.8 0.3 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.5 EGD93840.1 - 0.76 9.1 4.1 1.6 8.1 2.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Aldedh PF00171.17 EGD93841.1 - 1e-127 426.3 0.0 5.3e-96 321.7 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF1712 PF08217.6 EGD93842.1 - 7.6e-19 67.4 0.0 2.5e-18 65.7 0.0 1.9 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.14 EGD93843.1 - 1.5e-23 83.2 0.0 2.5e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase adh_short PF00106.20 EGD93844.1 - 9.9e-31 106.8 0.4 1.4e-30 106.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD93844.1 - 4.8e-21 75.6 0.1 5.7e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD93844.1 - 3.1e-12 46.5 0.3 4.2e-12 46.0 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD93844.1 - 0.00013 21.5 0.6 0.0005 19.5 0.2 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGD93844.1 - 0.05 12.4 0.0 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EGD93844.1 - 0.062 13.0 0.2 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EMP24_GP25L PF01105.19 EGD93845.1 - 6.1e-52 175.9 0.0 8.1e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_S46 PF10459.4 EGD93845.1 - 0.035 12.5 1.1 0.1 10.9 0.2 1.8 1 1 1 2 2 2 0 Peptidase S46 TMEMspv1-c74-12 PF11044.3 EGD93845.1 - 0.056 13.0 0.1 0.097 12.2 0.1 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PspB PF06667.7 EGD93845.1 - 0.062 13.2 0.6 0.13 12.1 0.4 1.6 1 0 0 1 1 1 0 Phage shock protein B Myb_DNA-bind_6 PF13921.1 EGD93846.1 - 0.044 13.9 0.8 0.18 11.9 0.0 2.5 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD93846.1 - 0.068 13.2 0.1 1.3 9.1 0.0 2.9 2 1 0 2 2 2 0 Myb-like DNA-binding domain V_ATPase_I PF01496.14 EGD93846.1 - 3.2 5.4 12.4 0.1 10.4 3.1 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EGD93846.1 - 7.3 6.1 10.4 0.1 12.2 1.1 2.1 2 1 0 2 2 2 0 IncA protein Meth_synt_2 PF01717.13 EGD93848.1 - 6.9e-144 478.7 0.0 1.3e-139 464.7 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EGD93848.1 - 1.5e-121 405.4 0.0 1.4e-110 369.4 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EGD93848.1 - 0.00055 18.9 0.0 0.13 11.1 0.0 2.7 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) LYTB PF02401.13 EGD93848.1 - 0.051 12.4 0.8 6.1 5.6 0.0 2.2 2 0 0 2 2 2 0 LytB protein Steroid_dh PF02544.11 EGD93849.1 - 6e-09 35.8 2.9 0.0046 16.7 0.1 4.0 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EGD93849.1 - 0.017 14.4 0.3 0.12 11.6 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Ufd2P_core PF10408.4 EGD93850.1 - 5.3e-186 619.5 14.8 6.5e-186 619.2 10.2 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EGD93850.1 - 1e-27 95.8 1.9 5e-27 93.6 0.3 2.6 2 0 0 2 2 2 1 U-box domain DUF1977 PF09320.6 EGD93852.1 - 1.6e-28 99.0 0.1 2.6e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EGD93852.1 - 2e-23 81.8 0.5 3.5e-23 81.0 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain ADP_ribosyl_GH PF03747.9 EGD93852.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF2416 PF10315.4 EGD93853.1 - 3e-06 27.4 0.6 2.2e-05 24.6 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2416) VIT1 PF01988.14 EGD93853.1 - 0.28 10.6 2.2 0.57 9.6 1.6 1.6 1 1 0 1 1 1 0 VIT family CTP_transf_2 PF01467.21 EGD93854.1 - 0.0078 16.2 0.0 0.014 15.4 0.0 1.5 2 0 0 2 2 2 1 Cytidylyltransferase Ydc2-catalyt PF09159.5 EGD93856.1 - 3.3e-94 315.4 0.0 4.1e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EGD93856.1 - 1.3e-05 25.0 0.0 0.94 9.3 0.0 3.3 3 0 0 3 3 3 2 Poxvirus A22 protein SAP PF02037.22 EGD93856.1 - 6.8e-05 22.2 0.5 0.00018 20.9 0.4 1.8 1 0 0 1 1 1 1 SAP domain Tcp11 PF05794.8 EGD93857.1 - 2.6e-78 263.7 0.0 4.4e-78 262.9 0.0 1.3 1 1 0 1 1 1 1 T-complex protein 11 Mito_fiss_reg PF05308.6 EGD93857.1 - 0.14 11.5 9.1 2.6 7.3 5.4 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Peptidase_S10 PF00450.17 EGD93858.1 - 1.1e-79 268.5 0.0 2.9e-79 267.1 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGD93858.1 - 0.0072 16.2 0.0 0.065 13.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family SOG2 PF10428.4 EGD93859.1 - 1.9e-100 336.6 2.4 1.9e-100 336.6 1.7 3.1 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 EGD93859.1 - 3.8e-17 61.4 4.2 3.2e-07 29.8 0.7 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD93859.1 - 3.9e-12 45.7 3.3 1.2e-06 28.1 0.3 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EGD93859.1 - 5.6e-09 34.8 7.7 0.038 14.0 0.1 6.0 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EGD93859.1 - 1.2e-05 24.6 4.6 3.4 8.2 0.1 6.0 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EGD93859.1 - 0.0039 17.0 4.5 0.68 10.1 0.1 5.0 4 1 0 4 4 4 1 Leucine Rich repeat ARID PF01388.16 EGD93859.1 - 0.12 12.2 0.1 0.69 9.7 0.0 2.3 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain MRP-S25 PF13741.1 EGD93860.1 - 4.4e-85 284.8 6.3 5.6e-85 284.4 4.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 PPR_2 PF13041.1 EGD93861.1 - 6.9e-10 38.7 0.8 0.0066 16.4 0.0 4.6 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 EGD93861.1 - 3.6e-08 33.0 6.3 0.33 11.3 0.0 6.5 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 EGD93861.1 - 3e-07 29.9 1.3 0.15 12.1 0.1 4.4 4 0 0 4 4 4 2 PPR repeat Helicase_C PF00271.26 EGD93862.1 - 8.9e-18 63.9 0.0 9.3e-15 54.2 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EGD93862.1 - 5.3e-17 61.8 0.0 3.6e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase KH_1 PF00013.24 EGD93863.1 - 4.2e-09 35.8 0.0 7.3e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EGD93863.1 - 3.4e-05 23.3 0.9 0.00034 20.1 0.1 2.8 2 0 0 2 2 2 1 KH domain ALS_ss_C PF10369.4 EGD93864.1 - 2.9e-19 68.5 0.0 7.3e-18 64.0 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EGD93864.1 - 5.2e-11 41.7 0.1 9.3e-11 40.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EGD93864.1 - 5.3e-09 35.7 0.2 1.1e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 EGD93864.1 - 0.019 14.6 0.1 6.7 6.5 0.0 2.5 2 0 0 2 2 2 0 ACT domain Cu-oxidase_3 PF07732.10 EGD93868.1 - 4.5e-42 142.5 0.1 1.9e-40 137.2 0.1 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGD93868.1 - 9.4e-38 128.8 8.9 1.2e-36 125.2 0.6 3.3 3 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EGD93868.1 - 6e-26 91.2 0.0 4.3e-25 88.4 0.0 2.2 2 1 0 2 2 2 1 Multicopper oxidase DUF3712 PF12505.3 EGD93869.1 - 2.4e-07 30.8 0.8 0.034 14.1 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) CD34_antigen PF06365.7 EGD93869.1 - 0.29 10.7 0.0 0.48 10.0 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family OTCace_N PF02729.16 EGD93870.1 - 3.5e-42 143.4 0.1 5.4e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EGD93870.1 - 6.2e-41 139.9 0.0 1e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3984 PF13136.1 EGD93871.1 - 1.1e-98 330.4 22.6 5.2e-98 328.2 15.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) Ndc1_Nup PF09531.5 EGD93872.1 - 3.5e-148 494.7 0.4 4e-148 494.5 0.3 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 EGD93873.1 - 6.3e-22 77.5 2.6 6.3e-22 77.5 1.8 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EGD93873.1 - 2.1e-17 62.5 1.8 2.1e-17 62.5 1.2 2.3 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EGD93873.1 - 0.00011 22.3 0.2 0.00011 22.3 0.1 2.5 2 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 EGD93873.1 - 0.00024 20.6 0.9 0.001 18.6 0.2 2.3 2 1 0 2 2 2 1 Synaptobrevin DUF334 PF03904.8 EGD93873.1 - 0.011 15.0 3.5 0.23 10.7 1.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF334) DUF552 PF04472.7 EGD93873.1 - 0.012 15.5 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF552) AAA_13 PF13166.1 EGD93873.1 - 0.025 13.0 6.9 0.035 12.6 4.8 1.2 1 0 0 1 1 1 0 AAA domain Herpes_US9 PF06072.6 EGD93873.1 - 0.036 13.8 0.3 0.069 12.9 0.2 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF883 PF05957.8 EGD93873.1 - 0.043 14.2 10.2 0.47 10.8 0.1 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF912 PF06024.7 EGD93873.1 - 0.11 12.5 0.3 0.33 11.0 0.2 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 EGD93873.1 - 0.21 11.8 1.5 0.86 9.9 0.0 2.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal T2SF PF00482.18 EGD93873.1 - 0.75 9.7 3.1 0.47 10.3 0.2 2.1 2 2 0 2 2 2 0 Type II secretion system (T2SS), protein F Cyto_heme_lyase PF01265.12 EGD93874.1 - 9.9e-76 254.7 0.0 2.8e-75 253.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase GHMP_kinases_N PF00288.21 EGD93876.1 - 1.2e-10 41.3 1.2 2.8e-10 40.0 0.8 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain IKI3 PF04762.7 EGD93877.1 - 0 1043.7 0.0 0 1043.5 0.0 1.0 1 0 0 1 1 1 1 IKI3 family DUF3465 PF11948.3 EGD93877.1 - 0.087 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) Apc4_WD40 PF12894.2 EGD93877.1 - 0.13 11.8 0.0 0.53 9.8 0.0 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_16 PF13432.1 EGD93877.1 - 3.3 8.5 6.1 0.34 11.6 0.4 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat COX7C PF02935.11 EGD93878.1 - 2.4e-15 56.0 2.2 3.9e-15 55.3 1.6 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.1 EGD93879.1 - 4.1e-103 344.1 0.7 6.7e-103 343.5 0.5 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EGD93879.1 - 2.8e-65 218.9 1.3 2.8e-65 218.9 0.9 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EGD93879.1 - 7.1e-22 77.6 0.1 2.8e-21 75.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD93879.1 - 1.3e-06 28.1 0.0 2.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD93879.1 - 0.0044 16.8 0.0 0.039 13.7 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EGD93879.1 - 0.028 13.3 0.0 0.068 12.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Cut8_C PF08559.5 EGD93880.1 - 1.8e-51 173.7 0.0 2.5e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EGD93880.1 - 3.9e-17 61.7 0.8 1.2e-16 60.2 0.6 1.9 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EGD93880.1 - 1.3e-10 41.0 2.1 2.6e-10 40.1 1.5 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Motile_Sperm PF00635.21 EGD93881.1 - 3.6e-25 87.7 0.3 5.8e-25 87.0 0.2 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain UBA PF00627.26 EGD93882.1 - 0.00038 20.1 0.0 0.00086 19.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2 PF00096.21 EGD93882.1 - 0.015 15.5 0.2 0.029 14.7 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Herpes_DNAp_acc PF04929.7 EGD93882.1 - 0.017 14.1 0.6 0.017 14.1 0.4 2.2 1 1 1 2 2 1 0 Herpes DNA replication accessory factor zf-C2H2_jaz PF12171.3 EGD93882.1 - 0.027 14.5 0.1 0.048 13.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding GATA PF00320.22 EGD93882.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 GATA zinc finger DUF3595 PF12166.3 EGD93882.1 - 0.22 10.2 3.1 0.27 10.0 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DIT1_PvcA PF05141.7 EGD93882.1 - 1.8 7.7 11.3 2.8 7.1 7.9 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF342 PF03961.8 EGD93882.1 - 1.9 6.8 20.8 2.7 6.3 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) zf-C2H2_2 PF12756.2 EGD93882.1 - 2.1 8.4 6.3 0.22 11.6 0.3 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) PLRV_ORF5 PF01690.12 EGD93882.1 - 3.1 6.8 18.2 4.3 6.3 12.6 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AAA_13 PF13166.1 EGD93882.1 - 4.5 5.6 24.5 6.8 5.0 17.0 1.3 1 0 0 1 1 1 0 AAA domain Rad52_Rad22 PF04098.10 EGD93883.1 - 1.5e-58 196.9 0.0 2.3e-58 196.2 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Aa_trans PF01490.13 EGD93885.1 - 1.2e-70 238.0 28.7 1.5e-70 237.7 19.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_S32 PF05579.8 EGD93886.1 - 0.00018 20.5 0.0 0.0016 17.4 0.0 2.2 3 0 0 3 3 3 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S64 PF08192.6 EGD93886.1 - 0.0063 14.9 0.1 0.012 13.9 0.0 1.3 1 1 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.1 EGD93886.1 - 0.033 14.1 0.0 0.17 11.9 0.0 2.2 2 1 0 2 2 2 0 Trypsin-like peptidase domain Y_phosphatase2 PF03162.8 EGD93888.1 - 1.7e-42 144.5 0.0 2.5e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EGD93888.1 - 4.2e-08 33.6 0.2 1.8e-07 31.5 0.0 2.0 2 1 1 3 3 3 1 Tyrosine phosphatase family DSPc PF00782.15 EGD93888.1 - 1.9e-05 24.2 0.0 2.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD93888.1 - 0.00063 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 EGD93888.1 - 0.088 11.5 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF1133 PF06576.6 EGD93888.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) TatD_DNase PF01026.16 EGD93890.1 - 3.6e-47 160.7 0.0 6.2e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.13 EGD93891.1 - 4.3e-109 364.6 0.0 5.5e-109 364.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EGD93891.1 - 1.3e-16 60.1 0.0 2.7e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ThiG PF05690.9 EGD93891.1 - 0.0011 18.1 0.0 0.043 12.8 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.10 EGD93891.1 - 0.0013 17.9 0.1 0.003 16.7 0.0 1.5 1 1 1 2 2 2 1 Nitronate monooxygenase Glu_synthase PF01645.12 EGD93891.1 - 0.0015 17.4 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EGD93891.1 - 0.053 12.3 2.3 0.067 12.0 0.0 2.3 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain SAP PF02037.22 EGD93893.1 - 3.4e-09 36.0 0.0 6.6e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain DUF4340 PF14238.1 EGD93893.1 - 0.04 13.6 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4340) PCMT PF01135.14 EGD93893.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNA_pol_Rpb1_5 PF04998.12 EGD93894.1 - 3.8e-87 292.0 0.0 1.7e-86 289.9 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EGD93894.1 - 9.5e-84 281.5 0.0 1.7e-83 280.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EGD93894.1 - 4.9e-67 225.0 0.0 9.4e-67 224.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGD93894.1 - 2e-34 118.6 0.0 4e-34 117.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EGD93894.1 - 1e-25 89.5 0.5 3.2e-25 87.9 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Asp PF00026.18 EGD93895.1 - 2.8e-70 237.0 1.3 3.4e-70 236.8 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGD93895.1 - 3e-06 27.2 0.0 9.4e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGD93895.1 - 4.1e-05 23.9 0.3 0.016 15.6 0.0 3.1 2 2 0 2 2 2 2 Aspartyl protease RVP PF00077.15 EGD93895.1 - 0.053 13.4 0.2 1.9 8.4 0.0 2.7 3 1 0 3 3 3 0 Retroviral aspartyl protease CarboxypepD_reg PF13620.1 EGD93896.1 - 0.059 13.4 1.8 0.39 10.8 0.2 2.3 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Vfa1 PF08432.5 EGD93897.1 - 3.4e-63 212.9 19.9 3.8e-63 212.8 13.8 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 EGD93897.1 - 0.00056 18.9 7.9 0.00066 18.7 5.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF4011 PF13195.1 EGD93897.1 - 0.022 14.7 5.3 0.029 14.3 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) MIP-T3 PF10243.4 EGD93897.1 - 0.05 12.0 29.7 0.062 11.7 20.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 IncA PF04156.9 EGD93897.1 - 0.067 12.7 6.8 0.098 12.2 4.7 1.3 1 0 0 1 1 1 0 IncA protein Ycf1 PF05758.7 EGD93897.1 - 0.078 10.6 14.5 0.086 10.5 10.0 1.0 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 EGD93897.1 - 0.11 12.3 16.5 0.17 11.7 11.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 EGD93897.1 - 0.18 11.7 11.1 0.24 11.3 7.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Herpes_Helicase PF02689.9 EGD93897.1 - 0.23 9.1 2.9 0.27 8.9 2.0 1.0 1 0 0 1 1 1 0 Helicase Raftlin PF15250.1 EGD93897.1 - 0.23 9.9 7.6 0.28 9.6 5.2 1.1 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.8 EGD93897.1 - 0.26 9.7 12.4 0.35 9.3 8.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF262 PF03235.9 EGD93897.1 - 0.36 10.7 6.7 0.42 10.5 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Daxx PF03344.10 EGD93897.1 - 0.39 9.1 20.2 0.47 8.8 14.0 1.1 1 0 0 1 1 1 0 Daxx Family Mnd1 PF03962.10 EGD93897.1 - 0.59 9.7 17.5 0.81 9.3 12.1 1.2 1 0 0 1 1 1 0 Mnd1 family Pox_Ag35 PF03286.9 EGD93897.1 - 0.66 9.4 21.2 0.91 9.0 14.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Atrophin-1 PF03154.10 EGD93897.1 - 0.94 7.5 19.4 1.5 6.8 13.5 1.4 1 0 0 1 1 1 0 Atrophin-1 family Caldesmon PF02029.10 EGD93897.1 - 1.1 7.5 30.1 1.5 7.1 20.9 1.1 1 0 0 1 1 1 0 Caldesmon DUF1510 PF07423.6 EGD93897.1 - 1.6 8.0 27.9 2.3 7.5 19.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EGD93897.1 - 1.6 6.6 21.2 2 6.3 14.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 EGD93897.1 - 2.1 7.4 10.6 2.8 7.0 7.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain UPF0560 PF10577.4 EGD93897.1 - 2.5 6.2 12.8 3 5.9 8.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Borrelia_P83 PF05262.6 EGD93897.1 - 2.5 6.2 22.6 2.9 6.0 15.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2413 PF10310.4 EGD93897.1 - 2.5 6.8 19.6 3.3 6.4 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4637 PF15470.1 EGD93897.1 - 2.9 7.4 12.3 4.9 6.7 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Zip PF02535.17 EGD93897.1 - 3.1 6.7 3.9 3.7 6.4 2.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NCKAP5 PF15246.1 EGD93897.1 - 3.3 7.0 21.0 4.6 6.5 14.6 1.2 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein CDC27 PF09507.5 EGD93897.1 - 3.4 6.8 30.0 4.1 6.5 20.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDHD PF02862.12 EGD93897.1 - 3.7 7.2 9.6 4.8 6.9 6.6 1.3 1 0 0 1 1 1 0 DDHD domain GCD14 PF08704.5 EGD93897.1 - 3.9 6.9 5.8 4.8 6.5 4.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit NARP1 PF12569.3 EGD93897.1 - 4.1 6.0 23.9 6.3 5.4 16.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ATP11 PF06644.6 EGD93897.1 - 5.4 6.4 15.6 6.9 6.0 10.8 1.3 1 0 0 1 1 1 0 ATP11 protein Phlebovirus_NSM PF07246.6 EGD93897.1 - 5.6 6.0 15.1 6.8 5.7 10.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M U79_P34 PF03064.11 EGD93897.1 - 9.9 5.6 22.0 7.7 5.9 14.3 1.6 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DSPc PF00782.15 EGD93898.1 - 3.6e-24 84.8 0.0 4.8e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD93898.1 - 0.018 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EGD93898.1 - 0.025 13.4 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 EGD93898.1 - 0.094 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-C2H2_4 PF13894.1 EGD93899.1 - 8.3e-05 22.6 21.6 0.012 15.8 2.8 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGD93899.1 - 0.0045 17.2 0.9 0.0045 17.2 0.6 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGD93899.1 - 0.0058 16.7 4.1 0.022 14.8 2.9 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding NosL PF05573.7 EGD93899.1 - 0.023 14.3 1.6 0.035 13.7 0.0 2.0 2 0 0 2 2 2 0 NosL zf-C2H2 PF00096.21 EGD93899.1 - 0.027 14.8 3.5 0.027 14.8 2.4 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF2614 PF11023.3 EGD93899.1 - 0.19 11.5 0.5 0.32 10.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) Cytochrome_C7 PF14522.1 EGD93899.1 - 6.8 6.4 15.4 1.6 8.4 7.9 2.1 2 1 0 2 2 2 0 Cytochrome c7 FA_desaturase PF00487.19 EGD93900.1 - 4e-29 101.8 7.8 7.5e-29 100.9 5.4 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EGD93900.1 - 2.2e-18 65.1 0.4 3.8e-18 64.4 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ABC1 PF03109.11 EGD93901.1 - 2.5e-32 111.3 0.0 4.5e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EGD93901.1 - 0.031 13.6 0.0 0.082 12.2 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Anp1 PF03452.9 EGD93902.1 - 5.8e-105 350.2 0.2 7.1e-105 349.9 0.1 1.1 1 0 0 1 1 1 1 Anp1 Recep_L_domain PF01030.19 EGD93903.1 - 3.2e-12 46.4 1.2 0.036 14.0 0.0 5.5 1 1 3 5 5 5 5 Receptor L domain Ecm33 PF12454.3 EGD93903.1 - 5.2e-11 42.2 0.8 1.6e-10 40.6 0.6 1.9 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein LRR_5 PF13306.1 EGD93903.1 - 0.0052 16.4 1.0 2.2 7.9 0.0 3.0 1 1 2 3 3 3 2 Leucine rich repeats (6 copies) HhH-GPD PF00730.20 EGD93904.1 - 1.6e-14 54.0 0.0 3.4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein UCR_14kD PF02271.11 EGD93905.1 - 1.1e-44 150.4 0.1 1.3e-44 150.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit PAS_3 PF08447.6 EGD93905.1 - 0.046 13.8 0.1 0.096 12.7 0.0 1.6 2 0 0 2 2 2 0 PAS fold Mito_carr PF00153.22 EGD93906.1 - 3.4e-66 219.0 0.0 4.8e-22 77.4 0.0 3.4 2 2 1 3 3 3 3 Mitochondrial carrier protein CHD5 PF04420.9 EGD93907.1 - 6.7e-58 194.8 1.8 8.1e-58 194.6 1.2 1.1 1 0 0 1 1 1 1 CHD5-like protein SUI1 PF01253.17 EGD93908.1 - 3.2e-14 52.4 0.0 8.9e-14 51.0 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 Trypsin PF00089.21 EGD93909.1 - 5.9e-09 35.8 0.0 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin Ank PF00023.25 EGD93910.1 - 5.4e-13 48.0 5.4 3.9e-06 26.3 1.4 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EGD93910.1 - 1.6e-11 44.3 0.1 3.3e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 EGD93910.1 - 1.8e-11 43.8 0.2 6e-11 42.1 0.2 1.9 1 0 0 1 1 1 1 IPT/TIG domain Ank_3 PF13606.1 EGD93910.1 - 7.3e-09 35.0 1.4 0.0025 17.9 0.4 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EGD93910.1 - 4.8e-08 32.9 2.0 1.3e-05 25.3 0.7 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGD93910.1 - 1.1e-07 32.2 1.0 3e-07 30.7 0.3 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Bap31 PF05529.7 EGD93910.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TRAPPC10 PF12584.3 EGD93911.1 - 3.7e-36 123.8 0.0 8e-36 122.7 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 EGD93911.1 - 0.019 14.4 0.1 0.036 13.5 0.1 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 G8 PF10162.4 EGD93911.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 G8 domain FA_desaturase PF00487.19 EGD93912.1 - 2.9e-24 85.9 13.9 4.5e-24 85.2 9.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EGD93912.1 - 1.5e-08 34.7 0.0 2.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Rad51 PF08423.6 EGD93913.1 - 1e-21 77.0 0.0 1.6e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EGD93913.1 - 3.1e-10 39.7 0.0 5.2e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGD93913.1 - 7.6e-07 28.4 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 KaiC DUF1254 PF06863.7 EGD93913.1 - 0.004 16.9 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1254) AAA_22 PF13401.1 EGD93913.1 - 0.0099 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.10 EGD93913.1 - 0.025 13.4 0.0 0.066 12.0 0.0 1.7 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain RecA PF00154.16 EGD93913.1 - 0.058 12.4 0.1 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 recA bacterial DNA recombination protein La PF05383.12 EGD93914.1 - 7.3e-18 64.1 0.0 1.5e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EGD93914.1 - 3.7e-05 23.2 0.1 0.00011 21.7 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD93914.1 - 8.3e-05 22.4 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rotamase PF00639.16 EGD93914.1 - 2.4 8.9 9.5 1.1 10.0 3.1 2.8 3 0 0 3 3 3 0 PPIC-type PPIASE domain Chitin_synth_2 PF03142.10 EGD93915.1 - 5.7e-23 81.0 2.0 5.7e-23 81.0 1.4 2.8 2 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EGD93915.1 - 1.8e-15 57.1 8.9 1.8e-15 57.1 6.2 2.8 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGD93915.1 - 2.2e-15 57.0 0.0 4.5e-15 56.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGD93915.1 - 0.013 15.2 0.0 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 HSP70 PF00012.15 EGD93916.1 - 2.9e-165 550.6 0.1 3.9e-165 550.2 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGD93916.1 - 3.6e-11 42.2 0.3 7.6e-11 41.1 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EGD93916.1 - 6.7e-05 22.7 0.6 0.036 13.9 0.0 3.5 3 1 0 3 3 3 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 EGD93916.1 - 0.056 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain NAM-associated PF14303.1 EGD93916.1 - 1.1 9.5 9.3 2.3 8.5 6.1 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Thiolase_N PF00108.18 EGD93917.1 - 8e-72 241.3 0.1 1.6e-71 240.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGD93917.1 - 2.7e-41 139.8 0.6 5.4e-41 138.8 0.4 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EGD93917.1 - 0.0025 17.4 0.2 0.4 10.3 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EGD93917.1 - 0.053 12.9 0.5 0.19 11.1 0.3 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain WLM PF08325.5 EGD93918.1 - 1.3e-45 155.5 0.0 1.9e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EGD93918.1 - 0.00012 21.9 0.2 0.00067 19.5 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 EGD93918.1 - 0.0075 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 SprT-like family LicD PF04991.8 EGD93919.1 - 2.8e-36 125.5 2.2 5.5e-35 121.3 1.6 2.0 1 1 0 1 1 1 1 LicD family HNH_2 PF13391.1 EGD93921.1 - 1.4e-08 34.3 0.0 3.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DASH_Ask1 PF08655.5 EGD93922.1 - 7.6e-32 108.9 0.4 1.4e-31 108.0 0.3 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 RhoGAP PF00620.22 EGD93923.1 - 2.7e-46 156.9 0.1 8.4e-46 155.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EGD93923.1 - 4e-14 52.4 18.7 1.8e-09 37.4 2.0 2.4 2 0 0 2 2 2 2 LIM domain zinc_ribbon_2 PF13240.1 EGD93923.1 - 0.89 9.1 0.0 0.89 9.1 0.0 4.1 3 1 2 5 5 5 0 zinc-ribbon domain 4HBT PF03061.17 EGD93925.1 - 0.018 15.1 0.3 0.046 13.8 0.2 1.8 1 1 0 1 1 1 0 Thioesterase superfamily Carn_acyltransf PF00755.15 EGD93926.1 - 8.1e-167 555.8 0.0 4.6e-166 553.3 0.0 1.8 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase JmjC PF02373.17 EGD93927.1 - 7.6e-38 129.2 1.2 1.4e-37 128.4 0.3 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EGD93927.1 - 1.1e-18 67.2 2.7 1.9e-18 66.4 1.8 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGD93927.1 - 1.4e-18 66.8 2.8 2.7e-18 65.9 1.9 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 EGD93927.1 - 7.3e-09 35.0 0.2 1.9e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 jmjN domain UQ_con PF00179.21 EGD93928.1 - 7.9e-24 83.6 0.0 1.3e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EGD93928.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 1 0 1 1 1 0 UEV domain AA_permease_2 PF13520.1 EGD93929.1 - 1e-57 195.6 48.8 1.4e-57 195.2 33.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD93929.1 - 6.4e-29 100.6 45.4 8.4e-29 100.2 31.5 1.1 1 0 0 1 1 1 1 Amino acid permease APH PF01636.18 EGD93930.1 - 9e-11 41.9 0.0 3.9e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD93930.1 - 0.00085 18.9 0.0 0.0018 17.8 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Cyclase PF04199.8 EGD93932.1 - 2.7e-09 36.9 0.0 4.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase PEP_mutase PF13714.1 EGD93933.1 - 2e-63 213.7 0.0 2.5e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MinE PF03776.9 EGD93933.1 - 0.056 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE MFS_1 PF07690.11 EGD93934.1 - 3.4e-33 114.8 27.6 6.3e-32 110.6 18.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF373 PF04123.8 EGD93934.1 - 0.022 13.8 0.1 0.046 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHDPS PF00701.17 EGD93935.1 - 3.3e-37 127.6 0.0 2.1e-36 125.0 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family zf-HC2 PF13490.1 EGD93935.1 - 0.14 12.1 0.2 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 Putative zinc-finger Ribonuc_L-PSP PF01042.16 EGD93936.1 - 1.3e-38 131.4 0.1 1.5e-38 131.2 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP QRPTase_C PF01729.14 EGD93936.1 - 0.0097 15.4 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain D-ser_dehydrat PF14031.1 EGD93937.1 - 1.6e-28 98.7 0.0 3.3e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EGD93937.1 - 1.2e-09 38.0 0.0 3.8e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain SpoIIIAH PF12685.2 EGD93939.1 - 0.024 14.1 2.2 0.03 13.8 1.5 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein PilX PF13681.1 EGD93939.1 - 0.033 14.6 0.4 0.05 14.0 0.3 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilX C-term Nup_retrotrp_bd PF10599.4 EGD93939.1 - 0.15 12.7 3.9 0.23 12.1 2.7 1.2 1 0 0 1 1 1 0 Retro-transposon transporting motif Herpes_DNAp_acc PF04929.7 EGD93939.1 - 0.19 10.6 6.6 0.23 10.3 4.5 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Spore_YhcN_YlaJ PF09580.5 EGD93939.1 - 5.6 7.0 14.5 9.6 6.2 10.1 1.4 1 1 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF3340 PF11818.3 EGD93939.1 - 6.8 6.6 11.0 5.7 6.8 6.4 1.7 1 1 1 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Velvet PF11754.3 EGD93940.1 - 3.1e-30 105.2 0.1 1.8e-29 102.8 0.0 2.1 1 1 1 2 2 2 1 Velvet factor PPTA PF01239.17 EGD93942.1 - 4.7e-05 22.5 1.6 0.28 10.6 0.5 2.4 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat FUSC PF04632.7 EGD93942.1 - 0.063 11.7 3.6 0.093 11.1 2.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AA_permease_2 PF13520.1 EGD93944.1 - 1.2e-45 155.8 50.7 1.5e-45 155.5 35.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD93944.1 - 1e-27 96.6 43.5 7e-27 93.8 30.2 1.9 1 1 0 1 1 1 1 Amino acid permease TRAM_LAG1_CLN8 PF03798.11 EGD93945.1 - 8.3e-38 129.9 22.5 8.3e-38 129.9 15.6 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EGD93945.1 - 3.8e-14 51.9 0.1 3.8e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein RRM_1 PF00076.17 EGD93946.1 - 2.5e-15 55.8 0.0 7e-15 54.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD93946.1 - 3.4e-10 39.7 0.0 6.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD93946.1 - 6.3e-07 29.1 0.1 1.2e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMN PF06003.7 EGD93947.1 - 5.2e-09 35.5 1.0 1.3e-07 31.0 0.1 2.1 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) Thiolase_C PF02803.13 EGD93948.1 - 9.5e-12 44.4 3.1 5.9e-11 41.8 0.0 2.7 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EGD93948.1 - 4.1e-08 32.7 0.1 3.7e-06 26.5 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EGD93948.1 - 8.7e-06 24.9 0.3 1.9e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EGD93948.1 - 0.0053 16.2 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 EGD93948.1 - 0.01 14.3 0.4 0.034 12.6 0.1 1.9 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) DUF3208 PF11482.3 EGD93948.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) YjgP_YjgQ PF03739.9 EGD93949.1 - 0.98 8.0 4.9 1.2 7.8 3.4 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Mito_carr PF00153.22 EGD93950.1 - 1.1e-42 143.6 4.8 3.2e-16 58.8 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein BRO1 PF03097.13 EGD93951.1 - 4.8e-112 374.4 0.0 6.4e-111 370.7 0.0 2.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EGD93951.1 - 2.5e-87 292.5 12.0 2.5e-87 292.5 8.3 1.9 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV zf-C4H2 PF10146.4 EGD93951.1 - 0.35 10.8 9.3 0.065 13.2 2.7 2.5 1 1 0 2 2 2 0 Zinc finger-containing protein bZIP_2 PF07716.10 EGD93952.1 - 9e-13 47.8 11.9 1.6e-12 47.0 8.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EGD93952.1 - 5.7e-07 29.4 11.1 9.7e-07 28.6 7.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAT1 PF09770.4 EGD93952.1 - 0.019 13.2 26.2 0.03 12.5 18.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.14 EGD93952.1 - 1 7.1 3.2 1.3 6.8 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.8 EGD93952.1 - 7.7 6.3 25.4 11 5.8 17.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-N PF05238.8 EGD93954.1 - 1.5e-116 389.7 0.1 1.9e-116 389.4 0.1 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DUF605 PF04652.11 EGD93954.1 - 0.19 11.0 5.9 0.35 10.2 4.1 1.4 1 0 0 1 1 1 0 Vta1 like zf-RING_2 PF13639.1 EGD93955.1 - 3.2e-06 26.8 2.5 3.2e-06 26.8 1.7 1.9 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EGD93955.1 - 2.2e-05 24.2 3.0 0.00011 22.0 0.4 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EGD93955.1 - 4.4e-05 23.3 5.0 0.0014 18.5 1.8 2.4 2 0 0 2 2 2 1 FANCL C-terminal domain SWIM PF04434.12 EGD93955.1 - 0.00011 21.6 0.2 0.0002 20.7 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-rbx1 PF12678.2 EGD93955.1 - 0.0038 17.3 1.2 0.0038 17.3 0.8 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger PHD PF00628.24 EGD93955.1 - 0.0063 16.1 3.7 0.013 15.1 2.6 1.6 1 0 0 1 1 1 1 PHD-finger RINGv PF12906.2 EGD93955.1 - 0.0089 16.0 4.3 0.019 14.9 3.0 1.6 1 0 0 1 1 1 1 RING-variant domain zf-CGNR PF11706.3 EGD93955.1 - 0.042 13.3 0.9 0.1 12.1 0.6 1.7 1 0 0 1 1 1 0 CGNR zinc finger PDE6_gamma PF04868.7 EGD93955.1 - 1.3 8.9 3.6 1.6 8.5 0.8 2.3 3 0 0 3 3 3 0 Retinal cGMP phosphodiesterase, gamma subunit zf-C3HC4_2 PF13923.1 EGD93955.1 - 2.7 8.0 6.4 1.1 9.3 2.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGD93955.1 - 8.7 6.0 9.3 0.35 10.5 2.4 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF974 PF06159.8 EGD93956.1 - 4.4e-72 242.5 0.0 5.4e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.16 EGD93957.1 - 2.7e-54 183.6 0.1 5.6e-54 182.6 0.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EGD93957.1 - 7.7e-20 70.7 0.3 1.6e-19 69.6 0.2 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EGD93957.1 - 9.4e-18 63.9 0.0 2.5e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.17 EGD93957.1 - 0.0021 17.7 4.7 0.0041 16.8 3.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 EGD93957.1 - 0.009 16.0 4.8 0.009 16.0 3.4 1.8 2 0 0 2 2 2 1 C1-like domain Vps39_2 PF10367.4 EGD93957.1 - 0.12 12.5 1.0 0.27 11.4 0.7 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 C1_2 PF03107.11 EGD93957.1 - 2.5 8.2 6.3 5 7.3 4.4 1.5 1 0 0 1 1 1 0 C1 domain PHD PF00628.24 EGD93957.1 - 2.8 7.7 8.6 2.3 7.9 4.5 2.0 1 1 1 2 2 2 0 PHD-finger RTA1 PF04479.8 EGD93958.1 - 2.4e-52 177.6 15.9 2.4e-52 177.6 11.0 1.8 2 0 0 2 2 2 1 RTA1 like protein DUF4173 PF13777.1 EGD93958.1 - 0.12 11.6 0.0 0.12 11.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) LHC PF00556.15 EGD93958.1 - 0.22 11.3 8.1 2.8 7.8 2.6 2.9 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit MBOAT_2 PF13813.1 EGD93961.1 - 8.6e-17 60.9 5.6 8.6e-17 60.9 3.9 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Fungal_trans_2 PF11951.3 EGD93962.1 - 0.0022 16.6 3.1 0.0024 16.5 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ninjurin PF04923.7 EGD93963.1 - 0.057 13.1 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Ninjurin Vicilin_N PF04702.7 EGD93963.1 - 0.071 12.7 3.6 0.11 12.1 2.5 1.2 1 0 0 1 1 1 0 Vicilin N terminal region Late_protein_L1 PF00500.13 EGD93963.1 - 0.094 11.2 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 L1 (late) protein HATPase_c_3 PF13589.1 EGD93965.1 - 9.4e-17 60.9 0.0 1.6e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EGD93965.1 - 1.7e-10 40.6 0.0 1.4e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EGD93965.1 - 5.3e-05 22.9 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RasGEF PF00617.14 EGD93966.1 - 8e-56 188.7 0.5 1.6e-55 187.8 0.3 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGD93966.1 - 3.2e-16 59.3 0.0 9.4e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EGD93966.1 - 1.6e-06 27.5 0.0 3.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGD93966.1 - 3.6e-05 23.0 0.0 8e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain ATPase_gene1 PF09527.5 EGD93967.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) FimP PF09766.4 EGD93968.1 - 0.0016 17.6 5.3 0.0016 17.6 3.7 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF2076 PF09849.4 EGD93968.1 - 0.023 14.7 9.3 0.024 14.7 6.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RED_N PF07808.8 EGD93968.1 - 0.033 13.4 3.8 0.034 13.3 2.6 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF3853 PF12964.2 EGD93968.1 - 0.034 13.9 0.4 0.051 13.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) Pex14_N PF04695.8 EGD93968.1 - 0.041 13.9 3.9 0.047 13.7 2.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TipAS PF07739.8 EGD93968.1 - 0.046 14.0 5.5 0.063 13.6 3.8 1.2 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain DUF2722 PF10846.3 EGD93968.1 - 0.054 12.5 8.2 0.067 12.2 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) ZU5 PF00791.15 EGD93968.1 - 0.062 12.9 0.5 0.099 12.3 0.3 1.4 1 0 0 1 1 1 0 ZU5 domain Activator_LAG-3 PF11498.3 EGD93968.1 - 0.086 11.5 23.5 0.098 11.3 16.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PAT1 PF09770.4 EGD93968.1 - 0.097 10.8 12.4 0.091 10.9 8.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EGD93968.1 - 0.14 10.3 21.3 0.15 10.2 14.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 EGD93968.1 - 0.17 11.2 6.1 0.21 10.8 4.2 1.2 1 0 0 1 1 1 0 Spt20 family FCP1_C PF09309.5 EGD93968.1 - 0.18 11.0 4.9 0.21 10.8 3.4 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF2381 PF09544.5 EGD93968.1 - 0.21 10.6 7.7 0.49 9.4 4.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2381) YqfQ PF14181.1 EGD93968.1 - 0.22 11.5 9.3 5.5 7.0 0.0 2.1 2 0 0 2 2 2 0 YqfQ-like protein YqzE PF14038.1 EGD93968.1 - 0.26 11.0 3.0 1.1 9.0 2.1 1.9 1 1 0 1 1 1 0 YqzE-like protein Prok-TraM PF09228.5 EGD93968.1 - 0.31 11.2 5.7 0.49 10.5 3.9 1.2 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM EIIBC-GUT_N PF03612.9 EGD93968.1 - 0.6 9.6 3.0 0.81 9.2 2.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4407 PF14362.1 EGD93968.1 - 1.1 8.1 8.9 1.4 7.7 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF912 PF06024.7 EGD93968.1 - 1.3 9.1 3.3 2 8.5 2.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Fe_bilin_red PF05996.7 EGD93968.1 - 1.6 8.1 9.1 2.2 7.7 6.3 1.1 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase OmpH PF03938.9 EGD93968.1 - 1.6 8.6 18.4 2.1 8.2 12.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pex16 PF08610.5 EGD93968.1 - 1.9 7.3 5.8 3.5 6.5 3.1 1.8 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) DUF945 PF06097.6 EGD93968.1 - 2.4 6.8 9.5 3.1 6.4 6.6 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) UPF0560 PF10577.4 EGD93968.1 - 4.5 5.3 10.5 5 5.2 7.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4175 PF13779.1 EGD93968.1 - 4.6 4.8 22.1 5.7 4.5 15.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) G0-G1_switch_2 PF15103.1 EGD93968.1 - 7.1 6.9 7.6 10 6.4 5.3 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 RAB3GAP2_N PF14655.1 EGD93968.1 - 8.1 5.3 8.7 9.9 5.0 6.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus GHMP_kinases_N PF00288.21 EGD93969.1 - 4.3e-14 52.3 0.0 1.1e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGD93969.1 - 0.00013 22.0 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal Med5 PF08689.5 EGD93970.1 - 3.6e-287 955.1 0.0 4.8e-287 954.7 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 BCDHK_Adom3 PF10436.4 EGD93970.1 - 0.026 14.0 0.6 1.5 8.3 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase ELFV_dehydrog_N PF02812.13 EGD93975.1 - 1.7e-45 153.7 0.0 2.1e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DPBB_1 PF03330.13 EGD93976.1 - 0.00067 19.6 0.6 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel MFS_1 PF07690.11 EGD93977.1 - 4.1e-10 38.9 32.9 4.1e-10 38.9 22.8 4.0 2 2 1 3 3 3 2 Major Facilitator Superfamily Chloroa_b-bind PF00504.16 EGD93977.1 - 0.19 12.0 2.0 0.25 11.6 0.1 2.2 2 0 0 2 2 2 0 Chlorophyll A-B binding protein Ribonuc_red_lgC PF02867.10 EGD93978.1 - 1.6e-214 713.4 0.0 2.4e-214 712.8 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EGD93978.1 - 8.4e-26 89.5 0.0 1.8e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EGD93978.1 - 9e-17 61.2 0.2 3.3e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain AAA_17 PF13207.1 EGD93980.1 - 1.1e-05 26.2 0.1 5.2e-05 24.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD93980.1 - 0.00014 22.1 0.1 0.014 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD93980.1 - 0.00076 19.5 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain PRK PF00485.13 EGD93980.1 - 0.00088 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 EGD93980.1 - 0.0023 16.8 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 EGD93980.1 - 0.0026 17.6 0.2 0.17 11.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGD93980.1 - 0.0042 17.2 0.0 0.0065 16.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGD93980.1 - 0.0058 16.3 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EGD93980.1 - 0.0067 15.5 1.2 0.094 11.8 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin Thymidylate_kin PF02223.12 EGD93980.1 - 0.035 13.4 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.1 EGD93980.1 - 0.042 13.9 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EGD93980.1 - 0.064 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 ArgK protein DUF2075 PF09848.4 EGD93980.1 - 0.16 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EGD93980.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Mur_ligase_M PF08245.7 EGD93982.1 - 1.2e-07 31.9 0.4 3.2e-07 30.5 0.3 1.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EGD93982.1 - 0.047 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Pkinase PF00069.20 EGD93983.1 - 1.3e-68 230.9 0.0 3.8e-68 229.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD93983.1 - 7.1e-51 172.7 0.0 1.7e-50 171.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD93983.1 - 0.0049 15.8 0.0 0.017 14.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like HEAT PF02985.17 EGD93983.1 - 0.049 13.7 0.4 1.2e+02 3.2 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat Peptidase_M24 PF00557.19 EGD93984.1 - 9.2e-47 159.2 0.0 1.1e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 FAA_hydrolase PF01557.13 EGD93984.1 - 0.0016 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TATR PF03430.8 EGD93984.1 - 0.094 11.3 2.9 0.12 10.9 2.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator TRAP_alpha PF03896.11 EGD93984.1 - 0.12 11.3 1.8 0.18 10.8 1.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pectinesterase PF01095.14 EGD93984.1 - 0.13 10.8 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase NST1 PF13945.1 EGD93984.1 - 0.21 11.6 4.0 0.33 10.9 2.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator CDC45 PF02724.9 EGD93984.1 - 0.64 7.9 4.9 0.87 7.5 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Cnd2 PF05786.9 EGD93984.1 - 0.8 8.1 9.3 1.2 7.5 6.5 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 DnaJ PF00226.26 EGD93985.1 - 2.8e-24 84.6 0.3 4.6e-24 83.9 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain YL1_C PF08265.6 EGD93985.1 - 0.089 12.3 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Porin_3 PF01459.17 EGD93986.1 - 1.1e-52 179.0 4.3 3.1e-51 174.2 3.0 2.1 1 1 0 1 1 1 1 Eukaryotic porin KdpC PF02669.10 EGD93986.1 - 0.049 13.3 0.6 0.078 12.6 0.4 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Asn_synthase PF00733.16 EGD93987.1 - 1e-65 221.7 0.0 1.4e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGD93987.1 - 1.9e-35 121.3 0.0 3.3e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGD93987.1 - 3.5e-27 94.9 0.0 6.5e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EGD93987.1 - 5.7e-08 32.2 0.0 1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EGD93987.1 - 0.00041 19.3 0.1 0.0039 16.1 0.0 2.0 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 EGD93987.1 - 0.0028 16.4 0.0 0.46 9.1 0.0 2.6 1 1 2 3 3 3 2 Glutamine amidotransferases class-II UQ_con PF00179.21 EGD93988.1 - 3.8e-46 155.9 0.0 4.3e-46 155.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD93988.1 - 2.8e-05 23.8 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B G-patch PF01585.18 EGD93989.1 - 5e-12 45.3 1.4 1e-11 44.4 1.0 1.5 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EGD93989.1 - 5.6e-06 26.1 0.1 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD93989.1 - 0.00012 21.5 0.0 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD93989.1 - 0.0016 18.3 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.23 EGD93990.1 - 1.7e-86 290.2 0.0 2e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD93990.1 - 3.3e-11 43.9 0.1 9.2e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EGD93990.1 - 0.00032 19.3 0.0 0.0022 16.6 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter YCII PF03795.9 EGD93991.1 - 2.4e-05 24.4 0.0 3.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Fungal_trans PF04082.13 EGD93992.1 - 2.8e-19 68.9 1.7 6.1e-19 67.8 1.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD93992.1 - 1e-06 28.5 13.8 1.8e-06 27.7 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGD93993.1 - 2.6e-11 42.7 0.0 9.2e-11 40.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Rad10 PF03834.9 EGD93994.1 - 7e-31 105.7 0.0 1.1e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EGD93994.1 - 0.0021 18.1 0.0 0.0049 17.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EGD93994.1 - 0.011 15.6 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.18 EGD93994.1 - 0.014 15.0 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Tape_meas_lam_C PF09718.5 EGD93994.1 - 0.049 13.5 0.9 0.26 11.2 0.1 2.4 2 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) PROL5-SMR PF15621.1 EGD93994.1 - 3.1 8.2 12.0 3.1 8.2 1.1 2.4 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family RRM_1 PF00076.17 EGD93995.1 - 2.7e-60 199.9 0.0 4.6e-19 67.8 0.0 5.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD93995.1 - 1.6e-42 143.3 0.0 1e-12 47.8 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD93995.1 - 1.6e-22 79.0 0.0 3e-06 26.9 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGD93995.1 - 0.00018 21.2 1.6 0.11 12.2 0.0 5.0 4 1 0 4 4 4 1 Limkain b1 NosL PF05573.7 EGD93995.1 - 0.036 13.7 0.0 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 NosL CSD PF00313.17 EGD93995.1 - 0.054 13.2 0.8 6.5 6.6 0.0 3.2 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain Cyt-b5 PF00173.23 EGD93996.1 - 2.8e-09 36.6 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gryzun PF07919.7 EGD93997.1 - 7.8e-118 394.1 0.2 1.1e-117 393.7 0.2 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EGD93997.1 - 1.2e-74 250.9 1.1 1e-66 224.9 1.0 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 EGD93997.1 - 0.0012 18.5 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF3656 PF12392.3 EGD93997.1 - 0.014 15.4 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Collagenase PhoD PF09423.5 EGD93998.1 - 8.7e-10 37.7 0.1 7.8e-07 28.0 0.1 2.2 2 1 0 2 2 2 2 PhoD-like phosphatase Rhomboid PF01694.17 EGD93999.1 - 2.2e-21 76.3 6.3 2.2e-21 76.3 4.4 1.7 2 0 0 2 2 2 1 Rhomboid family SlyX PF04102.7 EGD94000.1 - 0.11 12.8 1.2 5.3 7.4 0.4 2.3 2 0 0 2 2 2 0 SlyX Striatin PF08232.7 EGD94000.1 - 0.24 11.6 1.5 0.44 10.8 1.1 1.5 1 1 0 1 1 1 0 Striatin family NIF PF03031.13 EGD94001.1 - 3.2e-40 137.3 0.0 1.1e-37 129.0 0.0 2.3 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Aminotran_5 PF00266.14 EGD94002.1 - 3.2e-27 95.2 0.0 4e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGD94002.1 - 0.0045 15.9 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II adh_short PF00106.20 EGD94002.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EGD94002.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 KR domain B12-binding PF02310.14 EGD94002.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain Med9 PF07544.8 EGD94003.1 - 0.086 12.5 0.8 0.85 9.3 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HECT PF00632.20 EGD94004.1 - 1.1e-94 317.2 0.0 1.5e-94 316.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EGD94004.1 - 3.3e-32 109.9 28.3 5.6e-11 42.0 4.6 4.6 4 0 0 4 4 4 3 WW domain C2 PF00168.25 EGD94004.1 - 9.8e-17 60.5 0.0 2.5e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 EGD94005.1 - 9.6e-16 57.1 0.0 1.6e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD94005.1 - 1e-13 51.0 0.0 2.7e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD94005.1 - 1.1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 EGD94005.1 - 0.0056 14.5 0.3 0.0068 14.3 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Troponin PF00992.15 EGD94005.1 - 0.03 14.3 5.9 0.042 13.9 4.1 1.1 1 0 0 1 1 1 0 Troponin EMP24_GP25L PF01105.19 EGD94005.1 - 0.035 13.8 0.7 0.048 13.3 0.5 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CASP_C PF08172.7 EGD94005.1 - 0.036 13.0 0.1 0.049 12.6 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal GAS PF13851.1 EGD94005.1 - 0.063 12.4 2.0 0.085 12.0 1.4 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Flagellin_C PF00700.16 EGD94005.1 - 0.096 12.8 0.3 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Nup35_RRM_2 PF14605.1 EGD94005.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Med9 PF07544.8 EGD94005.1 - 0.12 12.0 1.0 0.21 11.3 0.7 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EGD94005.1 - 0.16 11.5 1.7 0.19 11.2 1.2 1.1 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EGD94005.1 - 0.8 10.0 5.0 1.3 9.3 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EGD94005.1 - 1.1 8.8 4.4 1.7 8.2 3.0 1.3 1 0 0 1 1 1 0 Septum formation initiator SUZ PF12752.2 EGD94006.1 - 1.4e-21 76.7 3.4 1.4e-21 76.7 2.4 3.0 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 EGD94006.1 - 1.4e-09 37.4 0.0 3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-CCHC_3 PF13917.1 EGD94007.1 - 4.9e-06 26.1 4.2 5.5e-06 26.0 1.1 2.6 2 0 0 2 2 2 1 Zinc knuckle cwf18 PF08315.7 EGD94008.1 - 1.1e-37 129.3 7.6 1.8e-37 128.6 5.3 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor PPR_2 PF13041.1 EGD94009.1 - 1.2e-21 76.3 0.2 7e-10 38.7 0.0 4.6 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.15 EGD94009.1 - 1.1e-14 53.3 0.0 0.00048 19.9 0.0 5.1 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.1 EGD94009.1 - 3.1e-14 51.9 3.0 0.038 14.2 0.0 6.0 6 0 0 6 6 6 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 EGD94009.1 - 1.6e-09 37.1 0.0 0.00021 20.7 0.0 4.0 4 0 0 4 4 4 2 PPR repeat TFIID-18kDa PF02269.11 EGD94010.1 - 2e-23 81.9 0.0 3.1e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 EGD94010.1 - 0.0023 18.0 0.0 0.0082 16.2 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 EGD94010.1 - 0.0089 16.2 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-S PF15630.1 EGD94010.1 - 0.033 14.3 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore component CENP-S JAB PF01398.16 EGD94011.1 - 5.5e-17 61.5 0.0 9.6e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGD94011.1 - 7.2e-15 55.0 0.1 1.3e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.8 EGD94011.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF1253 PF06862.7 EGD94012.1 - 3.7e-159 529.8 0.0 4.5e-159 529.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 EGD94012.1 - 0.00067 19.1 0.0 0.03 13.8 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase EamA PF00892.15 EGD94013.1 - 9.6e-19 67.6 23.1 6.3e-11 42.4 2.8 3.6 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EGD94013.1 - 0.00022 21.3 24.4 0.0024 18.0 3.5 3.3 2 1 0 3 3 3 2 Multidrug resistance efflux transporter CTP_transf_2 PF01467.21 EGD94014.1 - 1.1e-23 84.0 0.0 1.8e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase PP2C PF00481.16 EGD94015.1 - 2e-78 263.3 0.1 1.1e-77 260.8 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EGD94015.1 - 0.0018 17.7 0.3 0.0048 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C LpxD PF04613.9 EGD94015.1 - 0.042 13.3 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Nop14 PF04147.7 EGD94015.1 - 0.14 10.0 4.0 0.19 9.6 2.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGD94015.1 - 0.17 9.8 1.9 0.25 9.3 1.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Acetyltransf_1 PF00583.19 EGD94016.1 - 2.9e-15 56.0 0.3 5.2e-15 55.2 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD94016.1 - 2.4e-10 40.4 0.0 3.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD94016.1 - 2.4e-09 37.3 0.7 4e-09 36.5 0.3 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD94016.1 - 1.7e-08 34.1 0.1 2.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EGD94016.1 - 1.7e-06 27.9 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD94016.1 - 0.00029 20.6 0.0 0.00036 20.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD94016.1 - 0.0013 18.6 0.1 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EGD94016.1 - 0.024 14.2 0.2 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain P19Arf_N PF07392.7 EGD94016.1 - 0.2 11.8 1.7 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus Acetyltransf_6 PF13480.1 EGD94016.1 - 0.72 9.8 5.8 2.7 7.9 4.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZART1 PF12554.3 EGD94017.1 - 7.1e-27 92.6 1.4 8e-27 92.4 1.0 1.0 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SRP54_N PF02881.14 EGD94017.1 - 0.045 13.8 0.1 0.15 12.1 0.0 1.7 1 1 1 2 2 2 0 SRP54-type protein, helical bundle domain CUE PF02845.11 EGD94018.1 - 8e-12 44.4 0.0 1.8e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 CUE domain p47_phox_C PF08944.6 EGD94018.1 - 0.091 12.9 0.2 0.091 12.9 0.1 4.1 4 1 0 4 4 4 0 NADPH oxidase subunit p47Phox, C terminal domain HA2 PF04408.18 EGD94019.1 - 2.2e-21 75.7 0.0 4.5e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGD94019.1 - 2.6e-21 75.5 0.1 4.9e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGD94019.1 - 1.2e-12 47.5 0.0 4.5e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD94019.1 - 5.2e-05 22.7 0.2 0.00015 21.2 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGD94019.1 - 0.00022 21.3 0.1 0.00095 19.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EGD94019.1 - 0.011 14.7 0.1 0.03 13.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EGD94019.1 - 0.012 15.1 0.1 0.18 11.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EGD94019.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGD94019.1 - 0.042 13.5 0.1 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EGD94019.1 - 0.049 13.9 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 EGD94019.1 - 0.063 13.1 0.1 0.31 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGD94019.1 - 0.078 12.0 0.1 0.22 10.5 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 EGD94019.1 - 0.1 12.4 0.0 2.7 7.8 0.0 2.6 1 1 0 1 1 1 0 AAA domain PITH PF06201.8 EGD94020.1 - 2.1e-44 150.9 0.0 2.6e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.16 EGD94021.1 - 3.1e-30 104.7 9.5 3.8e-30 104.5 6.6 1.1 1 0 0 1 1 1 1 Snf7 MtaB PF12176.3 EGD94021.1 - 0.2 10.0 3.6 1.5 7.1 0.1 2.1 2 0 0 2 2 2 0 Methanol-cobalamin methyltransferase B subunit HSCB_C PF07743.8 EGD94021.1 - 0.21 12.0 11.9 1.8 9.0 0.3 2.8 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF2203 PF09969.4 EGD94021.1 - 1.4 9.1 6.3 1.7 8.9 0.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) AAA PF00004.24 EGD94022.1 - 3.5e-91 302.2 0.0 1e-45 155.1 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGD94022.1 - 1.7e-13 50.9 0.5 6.7e-05 22.9 0.0 4.2 3 2 1 4 4 3 2 AAA ATPase domain RuvB_N PF05496.7 EGD94022.1 - 6.6e-13 48.2 0.0 5.1e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGD94022.1 - 6.8e-12 45.6 0.1 0.0043 17.1 0.0 5.2 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 EGD94022.1 - 5.5e-11 43.3 0.0 5.7e-05 23.9 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EGD94022.1 - 7.4e-11 42.1 0.0 3.1e-05 23.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EGD94022.1 - 8.6e-11 42.0 0.0 0.00027 20.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EGD94022.1 - 5e-10 39.2 0.2 0.0012 18.6 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EGD94022.1 - 5.4e-10 38.6 0.0 0.00044 19.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 EGD94022.1 - 2.2e-09 37.2 0.0 0.002 18.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EGD94022.1 - 4.3e-09 35.5 0.0 0.00011 21.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EGD94022.1 - 5e-08 32.5 1.5 0.0072 16.0 0.1 3.5 2 2 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EGD94022.1 - 5.3e-08 33.0 0.0 0.0053 16.9 0.0 2.8 2 1 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EGD94022.1 - 1.4e-07 31.6 0.0 0.0029 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EGD94022.1 - 2.4e-07 30.3 0.5 0.027 13.9 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EGD94022.1 - 3.8e-07 30.4 0.0 0.015 15.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EGD94022.1 - 6.6e-07 28.6 1.8 0.019 14.1 0.0 2.8 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGD94022.1 - 7e-07 28.9 0.0 0.0025 17.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGD94022.1 - 1.9e-06 27.6 0.3 0.12 11.9 0.0 3.8 3 1 1 4 4 3 2 NACHT domain AAA_25 PF13481.1 EGD94022.1 - 6.8e-06 25.6 4.2 1.7 7.9 0.0 4.5 2 2 1 4 4 4 2 AAA domain Cytidylate_kin2 PF13189.1 EGD94022.1 - 3.3e-05 23.8 0.0 0.0085 16.0 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family ABC_tran PF00005.22 EGD94022.1 - 4e-05 23.9 0.0 0.15 12.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Sigma54_activ_2 PF14532.1 EGD94022.1 - 5.2e-05 23.3 0.0 0.44 10.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 EGD94022.1 - 6.6e-05 22.1 0.1 0.55 9.3 0.0 3.2 2 1 1 3 3 3 2 KaiC Sigma54_activat PF00158.21 EGD94022.1 - 7.2e-05 22.3 0.0 0.33 10.4 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 EGD94022.1 - 8.6e-05 21.8 0.0 0.2 10.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Arch_ATPase PF01637.13 EGD94022.1 - 0.0001 22.1 0.0 2.2 7.8 0.0 3.7 2 2 1 3 3 3 2 Archaeal ATPase SKI PF01202.17 EGD94022.1 - 0.00011 22.0 0.0 0.37 10.6 0.0 2.6 2 0 0 2 2 2 2 Shikimate kinase AFG1_ATPase PF03969.11 EGD94022.1 - 0.00039 19.3 0.0 0.14 10.9 0.0 2.7 2 1 0 2 2 2 1 AFG1-like ATPase ResIII PF04851.10 EGD94022.1 - 0.00048 20.0 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EGD94022.1 - 0.00053 18.9 0.0 0.27 10.0 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.10 EGD94022.1 - 0.00057 18.6 0.0 0.26 9.9 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 EGD94022.1 - 0.00073 19.1 0.0 0.49 9.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EGD94022.1 - 0.0013 17.6 0.0 0.046 12.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 EGD94022.1 - 0.0017 17.2 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EGD94022.1 - 0.0034 16.9 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EGD94022.1 - 0.0044 16.6 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EGD94022.1 - 0.0045 16.5 0.0 0.8 9.1 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 EGD94022.1 - 0.014 14.9 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 EGD94022.1 - 0.015 14.8 0.0 0.39 10.3 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 EGD94022.1 - 0.019 15.2 0.4 3.2 8.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain MSA-2c PF12238.3 EGD94022.1 - 0.021 14.4 0.5 0.062 12.9 0.3 1.7 1 1 0 1 1 1 0 Merozoite surface antigen 2c NTPase_1 PF03266.10 EGD94022.1 - 0.022 14.5 0.0 3.5 7.3 0.0 2.9 2 1 0 3 3 3 0 NTPase IPT PF01745.11 EGD94022.1 - 0.048 12.8 0.1 6.3 5.8 0.0 2.6 3 0 0 3 3 2 0 Isopentenyl transferase DUF2075 PF09848.4 EGD94022.1 - 0.071 12.0 0.0 4.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EGD94022.1 - 0.2 11.2 0.1 25 4.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain BOP1NT PF08145.7 EGD94023.1 - 4.8e-106 354.2 7.4 6.9e-106 353.7 5.1 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EGD94023.1 - 8e-27 92.1 10.9 2.5e-11 43.0 0.2 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat Zn_clus PF00172.13 EGD94024.1 - 4.1e-08 32.9 7.2 7.4e-08 32.1 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2197 PF09963.4 EGD94024.1 - 0.28 11.1 3.9 0.22 11.5 1.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Leo1 PF04004.8 EGD94025.1 - 3.1e-33 114.8 0.0 3.1e-33 114.8 0.0 2.0 2 0 0 2 2 2 1 Leo1-like protein Mob1_phocein PF03637.12 EGD94026.1 - 2.4e-29 102.2 2.1 6.3e-14 52.0 0.2 2.2 2 0 0 2 2 2 2 Mob1/phocein family IF-2B PF01008.12 EGD94027.1 - 7.8e-59 198.9 7.0 1e-48 165.7 2.4 3.0 2 1 0 2 2 2 2 Initiation factor 2 subunit family Ribosom_S12_S23 PF00164.20 EGD94028.1 - 2.7e-40 136.5 0.6 3.1e-40 136.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 THUMP PF02926.12 EGD94029.1 - 0.0092 15.8 0.6 0.014 15.3 0.4 1.2 1 0 0 1 1 1 1 THUMP domain EURL PF06937.6 EGD94029.1 - 0.53 9.6 3.2 0.36 10.1 0.7 1.7 2 0 0 2 2 2 0 EURL protein Ribosomal_L17 PF01196.14 EGD94031.1 - 1.3e-33 115.4 0.0 2.5e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 Metallophos_2 PF12850.2 EGD94032.1 - 1.3e-16 60.8 0.0 1.6e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGD94032.1 - 0.037 13.4 0.3 3.3 7.0 0.0 2.1 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase DUF202 PF02656.10 EGD94035.1 - 7.2e-13 48.5 4.5 7.2e-13 48.5 3.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4234 PF14018.1 EGD94035.1 - 0.022 14.4 0.8 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF2207 PF09972.4 EGD94035.1 - 0.057 12.0 0.7 0.059 11.9 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2615 PF11027.3 EGD94035.1 - 0.36 10.7 1.7 0.66 9.9 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Tctex-1 PF03645.8 EGD94036.1 - 6.2e-19 67.7 0.0 8.7e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family DERM PF14704.1 EGD94036.1 - 0.1 12.5 0.2 0.15 11.9 0.1 1.1 1 0 0 1 1 1 0 Dermatopontin WD40 PF00400.27 EGD94037.1 - 2.7e-44 147.4 21.5 1.9e-11 43.3 0.2 8.5 9 0 0 9 9 9 7 WD domain, G-beta repeat Nup160 PF11715.3 EGD94037.1 - 2.4e-06 25.9 2.8 0.1 10.7 0.2 4.5 5 0 0 5 5 5 4 Nucleoporin Nup120/160 Filament PF00038.16 EGD94038.1 - 0.0065 15.9 0.6 0.011 15.2 0.4 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF1318 PF07027.7 EGD94038.1 - 0.038 14.2 0.0 3.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) HNH_2 PF13391.1 EGD94039.1 - 5.3e-07 29.3 0.0 1.5e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease Rnk_N PF14760.1 EGD94039.1 - 0.13 12.4 0.8 0.57 10.3 0.1 2.3 2 0 0 2 2 2 0 Rnk N-terminus ketoacyl-synt PF00109.21 EGD94040.1 - 5.2e-76 255.4 0.0 1e-75 254.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGD94040.1 - 2.4e-43 148.7 0.0 3.7e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGD94040.1 - 2.4e-33 114.5 0.1 6.5e-33 113.1 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EGD94040.1 - 2.5e-31 109.6 0.0 5.5e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 EGD94040.1 - 2.3e-18 66.3 0.0 4.6e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EGD94040.1 - 7.2e-12 45.3 8.1 2.8e-06 27.4 0.3 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EGD94040.1 - 2e-05 24.5 0.1 0.00013 21.9 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD94040.1 - 0.0012 18.6 0.0 0.52 10.0 0.0 3.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 EGD94040.1 - 0.0012 17.8 0.0 0.0029 16.6 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Herpes_LAMP2 PF06126.6 EGD94040.1 - 0.47 8.7 1.8 0.75 8.1 1.3 1.2 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 FMO-like PF00743.14 EGD94041.1 - 2.7e-64 217.2 0.0 3.4e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGD94041.1 - 5.4e-21 75.5 0.0 6.8e-20 71.9 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD94041.1 - 3.7e-07 29.3 0.2 2.3e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGD94041.1 - 1.8e-05 24.5 0.0 0.0024 17.6 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGD94041.1 - 5.1e-05 23.2 0.0 0.00026 20.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.16 EGD94041.1 - 0.00066 19.3 0.0 0.094 12.2 0.0 2.4 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_8 PF13450.1 EGD94041.1 - 0.0011 18.9 0.0 0.0027 17.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EGD94041.1 - 0.0013 17.9 0.1 0.65 9.1 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EGD94041.1 - 0.0073 16.1 0.1 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGD94041.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EGD94041.1 - 0.038 14.2 0.0 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EGD94041.1 - 0.05 14.0 0.5 0.26 11.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD94041.1 - 0.09 11.6 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase IlvN PF07991.7 EGD94041.1 - 0.1 11.9 0.1 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain adh_short PF00106.20 EGD94042.1 - 7.1e-18 65.0 2.8 6.3e-16 58.7 2.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD94042.1 - 2.4e-08 34.0 0.0 0.001 18.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD94042.1 - 2.9e-08 33.5 0.5 5.1e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 EGD94042.1 - 0.013 14.4 0.1 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 EGD94042.1 - 0.074 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EGD94042.1 - 0.08 13.0 0.1 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 EGD94042.1 - 0.1 12.3 0.1 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EGD94042.1 - 0.16 11.5 0.3 0.24 11.0 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EGD94042.1 - 0.86 10.0 2.7 0.62 10.5 0.7 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fasciclin PF02469.17 EGD94043.1 - 2.5e-35 121.2 0.0 8.5e-22 77.5 0.1 2.3 2 0 0 2 2 2 2 Fasciclin domain Cu-oxidase_3 PF07732.10 EGD94044.1 - 6e-39 132.4 1.2 1.7e-38 130.9 0.3 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGD94044.1 - 3.2e-24 84.9 12.0 3.2e-21 75.2 0.3 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGD94044.1 - 6.2e-19 68.4 0.1 1.7e-18 67.0 0.0 1.8 1 1 0 1 1 1 1 Multicopper oxidase FXR1P_C PF12235.3 EGD94046.1 - 0.02 15.0 2.6 0.02 14.9 1.8 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Ribosomal_L19e PF01280.15 EGD94046.1 - 0.069 12.9 3.2 0.081 12.6 2.2 1.1 1 0 0 1 1 1 0 Ribosomal protein L19e DUF2968 PF11180.3 EGD94046.1 - 0.074 12.4 2.6 0.087 12.1 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF1633 PF07794.6 EGD94046.1 - 0.37 8.6 2.3 0.4 8.5 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Methyltransf_2 PF00891.13 EGD94047.1 - 1.5e-38 132.3 0.0 2.1e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGD94047.1 - 0.0036 17.0 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EGD94047.1 - 0.026 13.7 0.0 0.086 12.1 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.2 EGD94047.1 - 0.027 15.0 0.0 0.1 13.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGD94047.1 - 0.06 13.8 0.0 0.31 11.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.11 EGD94048.1 - 5.9e-40 137.0 46.7 1.9e-39 135.3 32.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD94048.1 - 1.7e-12 46.7 30.1 2.8e-10 39.3 5.4 3.2 2 1 0 2 2 2 2 Sugar (and other) transporter Bcl-2 PF00452.14 EGD94048.1 - 0.13 12.4 0.1 7.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family Fungal_trans PF04082.13 EGD94049.1 - 5.2e-17 61.5 2.2 1e-16 60.6 1.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD94049.1 - 5.1e-08 32.6 12.7 9.6e-08 31.8 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 EGD94050.1 - 3.2e-17 62.2 1.9 6.5e-17 61.2 1.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD94050.1 - 4.4e-06 26.5 0.0 1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like AflR PF08493.5 EGD94051.1 - 4.3e-07 29.2 4.3 4.3e-07 29.2 3.0 2.4 1 1 1 2 2 2 1 Aflatoxin regulatory protein AMOP PF03782.12 EGD94051.1 - 0.022 14.7 0.6 0.051 13.5 0.4 1.6 1 0 0 1 1 1 0 AMOP domain CTV_P13 PF06922.6 EGD94051.1 - 0.14 12.0 0.0 0.64 9.8 0.0 2.0 2 0 0 2 2 2 0 Citrus tristeza virus P13 protein VASP_tetra PF08776.6 EGD94051.1 - 0.14 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain p450 PF00067.17 EGD94053.1 - 7e-24 84.1 0.0 3.3e-22 78.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Transket_pyr PF02779.19 EGD94055.1 - 9.7e-43 145.7 0.0 1.6e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGD94055.1 - 4.2e-31 107.4 0.0 1.8e-30 105.4 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain DUF4200 PF13863.1 EGD94056.1 - 5.7 6.9 60.6 0.049 13.5 16.5 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4200) DUF21 PF01595.15 EGD94057.1 - 1.1e-30 106.3 0.1 1.6e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EGD94057.1 - 0.00013 21.6 0.5 0.077 12.8 0.0 2.7 2 0 0 2 2 2 2 CBS domain His_Phos_1 PF00300.17 EGD94058.1 - 1.9e-12 47.5 0.2 4e-12 46.4 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1799 PF08809.6 EGD94058.1 - 0.12 12.1 0.3 0.46 10.3 0.2 1.9 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) HECT PF00632.20 EGD94059.1 - 1.1e-16 60.8 0.0 2.9e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.2 EGD94060.1 - 6.2e-35 119.3 20.2 2.5e-30 104.5 2.1 3.7 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EGD94060.1 - 9.4e-08 32.0 9.5 6.7e-06 26.1 2.3 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGD94060.1 - 1.9e-07 31.0 5.4 8.2e-05 22.6 1.7 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding DUF2024 PF09630.5 EGD94060.1 - 0.00054 19.6 0.7 0.0087 15.7 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2024) zf-C2H2_6 PF13912.1 EGD94060.1 - 0.0047 16.7 0.1 0.0047 16.7 0.1 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger DUF693 PF05113.8 EGD94060.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF693) zf-C2H2 PF00096.21 EGD94060.1 - 0.58 10.6 18.9 0.3 11.5 0.2 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type Cytochrome_CBB3 PF13442.1 EGD94060.1 - 0.72 10.0 5.6 9.4 6.4 0.2 2.8 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III zf-C2H2_4 PF13894.1 EGD94060.1 - 0.88 10.0 15.6 5.4 7.5 0.3 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger AKAP95 PF04988.7 EGD94060.1 - 1.7 8.4 8.1 1.1 9.0 0.7 3.3 2 2 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Nucleo_P87 PF07267.6 EGD94061.1 - 2 7.0 7.4 3.2 6.3 5.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Abhydrolase_3 PF07859.8 EGD94062.1 - 1e-06 28.5 0.0 2.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD94062.1 - 0.00016 20.9 0.0 0.00027 20.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EGD94062.1 - 0.00076 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EGD94062.1 - 0.0032 17.2 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD94062.1 - 0.027 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 EGD94062.1 - 0.1 12.0 0.0 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 Putative esterase Pkinase PF00069.20 EGD94063.1 - 9.6e-71 237.9 0.0 1.1e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94063.1 - 1.6e-31 109.3 0.0 2e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD94063.1 - 0.00046 19.2 0.0 0.00074 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD94063.1 - 0.0026 17.5 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGD94063.1 - 0.033 13.0 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EGD94063.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL 2OG-FeII_Oxy_2 PF13532.1 EGD94064.1 - 1.4e-14 54.3 0.0 7.1e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Glyco_trans_2_3 PF13632.1 EGD94064.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 ZU5 PF00791.15 EGD94065.1 - 0.039 13.6 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 ZU5 domain zf-C2HC_2 PF13913.1 EGD94066.1 - 0.0033 17.0 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EGD94066.1 - 0.0076 16.3 0.1 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EGD94066.1 - 0.018 15.3 0.4 0.057 13.7 0.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD94066.1 - 0.084 13.2 0.4 0.2 12.0 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type FAD_binding_3 PF01494.14 EGD94067.1 - 1.7e-14 53.6 1.2 2.6e-07 30.0 0.0 3.1 2 1 0 3 3 3 2 FAD binding domain DAO PF01266.19 EGD94067.1 - 1.8e-05 23.8 3.6 0.003 16.5 0.1 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD94067.1 - 0.00016 20.6 0.3 0.00077 18.4 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Imm_superinfect PF14373.1 EGD94067.1 - 0.0014 18.1 1.5 0.0036 16.8 1.0 1.7 1 0 0 1 1 1 1 Superinfection immunity protein Pyr_redox_2 PF07992.9 EGD94067.1 - 0.024 14.4 0.2 0.23 11.3 0.1 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD94067.1 - 0.085 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 EGD94069.1 - 6.4e-43 146.8 41.2 6.4e-43 146.8 28.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD94069.1 - 4.6e-08 32.0 32.0 1.1e-07 30.7 20.7 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EGD94069.1 - 0.0017 16.6 6.2 0.0017 16.6 4.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PepSY_TM_2 PF13703.1 EGD94069.1 - 0.024 14.8 0.2 0.024 14.8 0.2 5.0 6 1 0 6 6 6 0 PepSY-associated TM helix Fungal_trans PF04082.13 EGD94070.1 - 1.2e-16 60.3 0.0 2.5e-16 59.3 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.21 EGD94071.1 - 5.1e-68 229.3 0.1 1.1e-67 228.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EGD94071.1 - 2.2e-46 157.8 0.0 4.1e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EGD94071.1 - 3.9e-46 157.8 0.1 1.1e-45 156.4 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EGD94071.1 - 4.9e-43 147.3 0.0 8.5e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGD94071.1 - 5e-38 130.6 0.0 1e-37 129.6 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGD94071.1 - 2.5e-29 101.5 0.1 9.4e-29 99.6 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EGD94071.1 - 1.2e-19 70.6 0.0 3.7e-19 69.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD94071.1 - 1e-12 48.3 0.0 2.8e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD94071.1 - 1.4e-12 47.6 0.0 3.3e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD94071.1 - 7.4e-10 38.6 0.0 1.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD94071.1 - 1.1e-08 35.5 0.0 3.5e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD94071.1 - 1.1e-06 27.9 0.0 2.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGD94071.1 - 6.1e-06 26.5 0.0 1.8e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGD94071.1 - 4.4e-05 23.6 0.3 0.00012 22.2 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGD94071.1 - 6.4e-05 22.0 0.2 0.00024 20.1 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 EGD94071.1 - 0.00033 20.6 0.0 0.001 19.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGD94071.1 - 0.0015 17.9 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 EGD94071.1 - 0.0073 15.7 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EGD94071.1 - 0.02 13.9 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.12 EGD94071.1 - 0.028 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.1 EGD94071.1 - 0.049 14.4 0.0 0.21 12.4 0.0 2.2 2 0 0 2 2 1 0 Methyltransferase domain AA_permease_2 PF13520.1 EGD94072.1 - 1.9e-54 184.8 48.1 2.3e-54 184.5 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD94072.1 - 1.2e-23 83.2 40.6 1.6e-23 82.8 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease Plasmod_dom_1 PF09715.5 EGD94072.1 - 0.058 13.3 1.2 0.27 11.1 0.8 2.3 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) DUF3237 PF11578.3 EGD94074.1 - 5e-08 32.3 0.0 1e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) DLH PF01738.13 EGD94076.1 - 4.1e-13 49.1 0.0 5.4e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGD94076.1 - 0.046 13.4 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD94076.1 - 0.046 13.2 0.2 0.13 11.7 0.0 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold Cu-oxidase_3 PF07732.10 EGD94077.1 - 2.5e-45 152.9 0.1 3.9e-44 149.1 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGD94077.1 - 1.4e-38 131.5 5.2 5.4e-35 119.9 0.1 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EGD94077.1 - 5.4e-32 110.8 0.1 1.7e-31 109.2 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase CHB_HEX_C_1 PF13290.1 EGD94078.1 - 2.4 7.9 5.2 4.8 7.0 0.6 3.0 3 1 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain LysM PF01476.15 EGD94079.1 - 2.5e-16 59.2 0.0 9.8e-08 31.7 0.0 3.3 3 0 0 3 3 3 3 LysM domain HTH_28 PF13518.1 EGD94079.1 - 0.05 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EGD94079.1 - 0.14 12.1 0.0 3.8 7.5 0.0 2.5 3 0 0 3 3 3 0 Transposase MFS_1 PF07690.11 EGD94080.1 - 9.5e-23 80.4 47.4 6.8e-15 54.6 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Cutinase PF01083.17 EGD94081.1 - 1.7e-11 44.1 0.0 1.6e-06 28.0 0.1 2.1 1 1 0 2 2 2 2 Cutinase Glyco_hydro_cc PF11790.3 EGD94083.1 - 1.7e-61 207.6 1.4 2e-61 207.4 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Peptidase_S8 PF00082.17 EGD94084.1 - 9.1e-53 179.2 3.3 1.3e-52 178.6 2.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EGD94084.1 - 3.1e-27 94.1 3.5 4.9e-27 93.5 0.7 2.5 3 0 0 3 3 3 1 Proprotein convertase P-domain DUF3328 PF11807.3 EGD94086.1 - 5.1e-30 104.7 5.7 6.5e-30 104.4 3.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EGD94087.1 - 6.9e-18 65.1 0.5 1.1e-17 64.4 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_2 PF00891.13 EGD94088.1 - 5e-38 130.6 0.1 6.7e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGD94088.1 - 1.2e-06 28.3 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD94088.1 - 4e-06 27.3 0.1 3.3e-05 24.4 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain CheR PF01739.13 EGD94088.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain MTS PF05175.9 EGD94088.1 - 0.033 13.5 0.0 0.072 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EGD94088.1 - 0.069 13.6 0.0 0.3 11.5 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain UDPG_MGDP_dh PF00984.14 EGD94088.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain DUF1998 PF09369.5 EGD94089.1 - 3.1e-11 43.6 0.1 3.5e-08 33.8 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1998) Pox_A9 PF04835.7 EGD94089.1 - 0.085 12.7 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 A9 protein conserved region Fungal_trans_2 PF11951.3 EGD94090.1 - 2.2e-10 39.7 6.9 9.7e-10 37.5 4.8 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD94090.1 - 7e-06 25.8 10.8 1.4e-05 24.8 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EGD94091.1 - 2e-18 66.2 29.5 6.4e-17 61.3 10.7 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD94091.1 - 3e-11 42.5 21.2 7.7e-11 41.2 6.6 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EGD94091.1 - 5.6e-06 24.8 7.5 0.00043 18.6 1.5 2.5 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) DUF3357 PF11837.3 EGD94091.1 - 0.39 10.5 3.5 1.8 8.4 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) AMP-binding PF00501.23 EGD94092.1 - 8.6e-48 162.7 0.0 1.4e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EGD94092.1 - 7.5e-15 54.9 0.1 1.5e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 EGD94092.1 - 2.9e-09 36.0 15.8 1.9e-06 27.0 0.1 6.9 8 1 0 8 8 8 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGD94092.1 - 3.2e-05 23.3 21.8 0.03 13.8 0.0 5.9 5 2 1 6 6 6 4 Hexapeptide repeat of succinyl-transferase AMP-binding_C PF13193.1 EGD94092.1 - 0.032 15.1 0.0 0.1 13.5 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain zf-RING_2 PF13639.1 EGD94093.1 - 6.9e-15 54.5 8.0 1.1e-14 53.9 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGD94093.1 - 2e-09 37.4 3.9 3.6e-09 36.6 2.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGD94093.1 - 3.7e-06 26.8 8.2 6e-06 26.1 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD94093.1 - 1e-05 25.1 8.1 1.6e-05 24.4 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD94093.1 - 5.8e-05 22.7 6.2 8.8e-05 22.1 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGD94093.1 - 9.1e-05 22.2 2.9 0.00024 20.9 2.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EGD94093.1 - 0.00016 21.2 4.9 0.00025 20.6 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EGD94093.1 - 0.009 16.0 9.4 0.014 15.3 6.5 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.1 EGD94093.1 - 0.034 13.8 2.4 0.088 12.5 1.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 EGD94093.1 - 0.084 12.4 3.6 0.16 11.5 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EGD94093.1 - 0.092 12.7 5.7 0.17 11.8 4.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 EGD94093.1 - 2.2 8.0 8.6 1.4 8.7 4.8 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EGD94093.1 - 4.3 7.4 6.8 7.4 6.6 4.7 1.4 1 0 0 1 1 1 0 RING-like domain ECM11 PF15463.1 EGD94094.1 - 8.4e-38 129.7 0.4 2.3e-37 128.3 0.0 2.0 2 0 0 2 2 2 1 Extracellular mutant protein 11 RNA_pol_I_TF PF04090.7 EGD94095.1 - 1.6e-06 27.5 0.0 0.0016 17.7 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor bZIP_Maf PF03131.12 EGD94096.1 - 1.1e-05 25.5 15.2 1.1e-05 25.5 10.6 2.9 1 1 1 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EGD94096.1 - 0.00012 21.8 11.9 0.00012 21.8 8.3 3.4 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 EGD94096.1 - 0.023 14.6 27.6 0.14 12.1 14.4 3.3 1 1 1 2 2 2 0 bZIP transcription factor DUF2205 PF10224.4 EGD94096.1 - 0.21 11.1 14.6 0.24 10.9 7.6 2.5 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) APG6 PF04111.7 EGD94096.1 - 1.3 7.9 17.5 2.8 6.9 12.2 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 EGD94096.1 - 1.6 8.3 18.3 1.1 8.9 10.9 1.9 1 1 0 1 1 1 0 Mnd1 family AAA_23 PF13476.1 EGD94096.1 - 5.9 7.1 11.9 11 6.3 8.2 1.4 1 0 0 1 1 1 0 AAA domain zf-CCCH PF00642.19 EGD94100.1 - 1.6e-11 43.6 26.4 0.0021 17.6 1.1 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TFIIF_beta PF02270.10 EGD94101.1 - 1.5e-88 297.1 8.6 1.8e-88 296.9 6.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DUF859 PF05895.7 EGD94101.1 - 0.17 10.1 0.1 0.21 9.8 0.1 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) PCI PF01399.22 EGD94102.1 - 3.7e-11 43.2 0.0 1e-10 41.8 0.0 1.7 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EGD94102.1 - 2.6e-07 30.1 0.0 5.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 NAD_binding_4 PF07993.7 EGD94103.1 - 3.9e-33 114.4 0.0 1.3e-32 112.7 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 EGD94103.1 - 3.5e-27 94.8 0.0 7.2e-26 90.5 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EGD94103.1 - 1.4e-12 47.5 0.0 2.5e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGD94103.1 - 7.5e-08 32.5 0.0 2.2e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EGD94103.1 - 0.018 13.9 0.0 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGD94103.1 - 0.081 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.17 EGD94104.1 - 4e-76 256.4 0.0 4.5e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EGD94105.1 - 3.9e-14 52.9 0.0 7.9e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD94105.1 - 3e-07 30.2 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD94106.1 - 3.1e-31 108.9 0.2 3.8e-31 108.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD94106.1 - 1.5e-25 90.0 1.2 2.4e-25 89.3 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD94106.1 - 1.3e-10 41.2 1.2 3.3e-10 39.9 0.8 1.7 1 1 0 1 1 1 1 KR domain Fungal_trans PF04082.13 EGD94107.1 - 3.1e-07 29.5 0.1 8.9e-07 28.0 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD94107.1 - 4.5e-07 29.6 8.2 4.5e-07 29.6 5.7 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl_transf_1 PF00698.16 EGD94108.1 - 5e-88 295.4 0.0 8.3e-88 294.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EGD94108.1 - 3.7e-78 262.5 0.6 8.9e-78 261.2 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EGD94108.1 - 7.6e-60 201.6 0.2 6.6e-59 198.6 0.0 2.5 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EGD94108.1 - 7.3e-49 165.8 1.7 3.7e-48 163.5 0.0 3.0 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGD94108.1 - 6.3e-43 145.3 0.7 1.8e-42 143.9 0.5 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EGD94108.1 - 3.9e-15 55.7 0.0 6.6e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EGD94108.1 - 7e-13 48.6 0.0 2.2e-11 43.8 0.0 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGD94108.1 - 2e-05 23.7 0.6 8.5e-05 21.6 0.4 2.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain MFS_1 PF07690.11 EGD94109.1 - 8.4e-24 83.9 30.1 1.1e-23 83.5 20.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PPV_E1_C PF00519.12 EGD94109.1 - 0.082 11.5 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase DUF1469 PF07332.6 EGD94109.1 - 4.6 6.9 8.6 0.4 10.4 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) WD40 PF00400.27 EGD94110.1 - 6.9e-14 51.1 2.9 0.14 12.0 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat FAD_binding_2 PF00890.19 EGD94112.1 - 1e-58 199.1 0.5 1.9e-58 198.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EGD94112.1 - 1.4e-20 72.8 0.2 4.9e-19 67.9 0.1 3.0 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EGD94112.1 - 1.1e-11 44.2 2.8 1.6e-10 40.4 1.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGD94112.1 - 1.1e-10 41.2 0.7 4.1e-10 39.3 0.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD94112.1 - 3.8e-09 36.4 1.3 1.9e-08 34.1 0.1 2.6 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGD94112.1 - 8.7e-06 24.4 1.0 5e-05 21.9 0.7 2.1 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EGD94112.1 - 2.6e-05 24.2 2.8 0.0045 16.8 1.5 2.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGD94112.1 - 7e-05 21.8 1.7 0.019 13.8 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EGD94112.1 - 0.0049 16.9 1.5 0.023 14.7 0.7 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGD94112.1 - 0.005 15.9 1.2 0.0098 14.9 0.8 1.5 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EGD94112.1 - 0.0052 15.9 0.4 3.1 6.7 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 EGD94112.1 - 0.007 15.4 0.1 0.017 14.2 0.1 1.7 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EGD94112.1 - 0.014 15.1 1.3 0.19 11.4 0.9 2.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding MSP1_C PF07462.6 EGD94112.1 - 0.35 9.2 4.5 0.55 8.5 3.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pyr_redox PF00070.22 EGD94112.1 - 0.85 10.0 4.0 3.8 7.9 0.6 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAH PF02671.16 EGD94113.1 - 3.8e-46 154.4 0.5 1.1e-17 63.4 0.2 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EGD94113.1 - 4.1e-41 138.8 0.1 1.2e-40 137.3 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Glyco_hydro_17 PF00332.13 EGD94114.1 - 0.00049 19.2 0.2 0.015 14.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 BLIP PF07467.6 EGD94114.1 - 0.013 15.1 0.2 0.033 13.8 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase inhibitor (BLIP) MFS_1 PF07690.11 EGD94115.1 - 3.3e-41 141.1 65.1 1.5e-39 135.7 45.0 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD94115.1 - 2.1e-16 59.5 9.9 2.1e-16 59.5 6.9 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EGD94115.1 - 1.3e-15 56.6 25.3 2.1e-15 55.9 17.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 EGD94115.1 - 0.0076 14.7 0.6 0.0076 14.7 0.4 2.9 4 0 0 4 4 4 2 Vacuole effluxer Atg22 like Sel1 PF08238.7 EGD94116.1 - 6.9e-33 112.3 36.2 3e-05 24.5 1.9 7.8 8 0 0 8 8 8 7 Sel1 repeat TPR_11 PF13414.1 EGD94116.1 - 0.13 11.9 4.7 0.83 9.3 0.6 3.3 2 1 1 3 3 3 0 TPR repeat Macoilin PF09726.4 EGD94116.1 - 3.1 5.9 13.3 5.4 5.1 9.2 1.3 1 0 0 1 1 1 0 Transmembrane protein Chitin_synth_2 PF03142.10 EGD94117.1 - 4.5e-294 975.7 0.1 7.1e-294 975.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EGD94117.1 - 3.9e-18 65.8 1.2 1.5e-17 63.9 0.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGD94117.1 - 1.2e-13 51.4 0.0 4.5e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EGD94117.1 - 1.1e-05 25.0 0.0 2.9e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EGD94117.1 - 2.1e-05 23.8 0.0 0.00024 20.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGD94117.1 - 0.012 15.3 0.0 0.051 13.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 Selenoprotein_S PF06936.6 EGD94117.1 - 0.084 12.4 2.8 0.69 9.4 2.2 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) RskA PF10099.4 EGD94118.1 - 0.041 13.6 1.8 0.044 13.5 0.4 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA WD40 PF00400.27 EGD94119.1 - 3.6e-09 36.1 0.1 5.8e-07 29.1 0.0 3.7 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF123 PF01986.11 EGD94119.1 - 0.0083 16.2 0.1 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF123 ATG22 PF11700.3 EGD94121.1 - 1e-130 436.4 31.9 1.2e-130 436.2 22.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Ras PF00071.17 EGD94122.1 - 7.8e-59 197.6 0.2 9e-59 197.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD94122.1 - 4.4e-19 69.1 0.1 7.8e-19 68.3 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGD94122.1 - 8.7e-15 54.3 0.1 1.1e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGD94122.1 - 1.3e-08 34.5 0.0 2.3e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGD94122.1 - 1.9e-07 30.4 0.0 2.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGD94122.1 - 4e-06 26.7 0.0 7.5e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGD94122.1 - 0.0079 16.3 0.1 0.81 9.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD94122.1 - 0.018 15.0 0.2 0.12 12.3 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EGD94122.1 - 0.025 13.7 0.2 0.086 12.0 0.0 1.9 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAT PF03417.11 EGD94122.1 - 0.068 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase AAA_14 PF13173.1 EGD94122.1 - 0.088 12.7 0.1 0.16 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain NPHI_C PF08469.5 EGD94122.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal Mitofilin PF09731.4 EGD94123.1 - 7e-153 510.3 16.5 1e-152 509.8 11.4 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Exonuc_VII_L PF02601.10 EGD94123.1 - 0.16 11.0 10.0 0.27 10.3 6.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pex14_N PF04695.8 EGD94123.1 - 4.3 7.3 12.0 0.059 13.4 0.6 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ATP-synt_B PF00430.13 EGD94123.1 - 5.2 6.8 22.0 6.1 6.6 5.6 2.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4363 PF14276.1 EGD94123.1 - 6 6.5 8.0 3.7 7.2 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) OmpH PF03938.9 EGD94123.1 - 9 6.2 18.5 7 6.5 11.4 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FimH_man-bind PF09160.5 EGD94125.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 FimH, mannose binding DSBA PF01323.15 EGD94127.1 - 1.7e-12 47.3 0.0 2.4e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Bromodomain PF00439.20 EGD94128.1 - 2.2e-23 81.9 0.2 3.9e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 EGD94128.1 - 1.6e-09 37.6 0.2 3.6e-09 36.5 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD94128.1 - 2.8e-09 36.9 0.3 8e-09 35.5 0.2 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD94128.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Methyltransf_16 PF10294.4 EGD94130.1 - 4.9e-48 162.8 0.0 7.2e-48 162.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EGD94130.1 - 4.1e-05 23.5 0.1 0.00012 22.1 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD94130.1 - 4.6e-05 23.0 0.1 0.0004 19.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGD94130.1 - 0.00083 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGD94130.1 - 0.0011 19.3 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD94130.1 - 0.0012 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD94130.1 - 0.0012 19.2 0.0 0.0045 17.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD94130.1 - 0.0053 17.3 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGD94130.1 - 0.024 13.7 0.1 0.039 13.0 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Orn_Arg_deC_N PF02784.11 EGD94131.1 - 2.5e-76 256.2 0.0 3.5e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EGD94131.1 - 1.5e-28 98.8 0.0 2.4e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EGD94131.1 - 0.011 14.9 0.0 0.025 13.8 0.0 1.5 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel cobW PF02492.14 EGD94132.1 - 9.4e-39 132.6 0.0 1.5e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EGD94132.1 - 0.0011 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EGD94132.1 - 0.008 15.9 0.0 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EGD94132.1 - 0.03 14.4 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGD94132.1 - 0.033 13.7 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Pox_A32 PF04665.7 EGD94132.1 - 0.07 12.4 0.1 0.16 11.1 0.0 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_29 PF13555.1 EGD94132.1 - 0.085 12.3 0.2 1.1 8.7 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EGD94132.1 - 0.091 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EGD94132.1 - 0.14 11.0 0.1 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SET PF00856.23 EGD94133.1 - 7.1e-06 26.4 0.1 3e-05 24.3 0.0 1.9 2 1 0 2 2 2 1 SET domain Glyco_transf_54 PF04666.8 EGD94134.1 - 1.7e-13 49.9 0.0 4.1e-10 38.8 0.0 3.1 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF2754 PF10953.3 EGD94134.1 - 0.0073 16.3 0.2 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2754) DUF3431 PF11913.3 EGD94135.1 - 1.7e-85 286.0 0.0 2.1e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Herpes_gE PF02480.11 EGD94136.1 - 0.15 10.3 0.1 0.19 9.9 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DNA_mis_repair PF01119.14 EGD94137.1 - 4.5e-11 42.2 0.0 1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 EGD94137.1 - 1.6e-09 37.4 0.0 4.1e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGD94137.1 - 8.4e-07 28.7 0.0 1.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase APH PF01636.18 EGD94138.1 - 1.5e-11 44.4 0.0 4.6e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.11 EGD94139.1 - 8.6e-32 110.2 29.3 8.6e-32 110.2 20.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily zf-DHHC PF01529.15 EGD94140.1 - 1.5e-36 125.4 0.6 2.5e-36 124.6 0.4 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF2254 PF10011.4 EGD94140.1 - 0.021 13.3 0.2 0.031 12.7 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Transglut_core3 PF13471.1 EGD94140.1 - 0.17 11.7 1.0 0.35 10.6 0.7 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily Acetyltransf_3 PF13302.1 EGD94141.1 - 1.4e-32 112.8 0.0 2e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD94141.1 - 0.00047 20.1 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EGD94141.1 - 0.043 13.6 0.0 0.08 12.8 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EGD94142.1 - 4.3e-73 245.6 0.2 8.2e-73 244.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94142.1 - 5.6e-45 153.4 0.0 9e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD94142.1 - 6.9e-07 28.5 0.0 1.4e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like POLO_box PF00659.13 EGD94142.1 - 2.8e-05 23.9 0.0 0.065 13.2 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 EGD94142.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.7 EGD94143.1 - 3.3e-33 114.2 0.9 7.8e-33 113.0 0.6 1.6 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Med11 PF10280.4 EGD94143.1 - 0.019 15.0 1.1 0.019 15.0 0.7 1.9 2 0 0 2 2 2 0 Mediator complex protein Myosin_head PF00063.16 EGD94144.1 - 2.9e-233 775.8 3.8 4.3e-233 775.3 2.7 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EGD94144.1 - 5.5e-45 153.1 0.0 1e-44 152.2 0.0 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EGD94144.1 - 9e-12 44.2 0.0 1.9e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGD94144.1 - 9.1e-10 37.8 0.0 3.6e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EGD94144.1 - 2.4e-09 36.6 0.0 6.8e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EGD94144.1 - 0.0017 18.4 0.0 0.0077 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain IQ PF00612.22 EGD94144.1 - 0.0041 16.6 7.3 0.48 10.2 0.7 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.7 EGD94144.1 - 0.012 14.9 0.4 1.7 7.9 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 EGD94144.1 - 0.023 13.8 0.0 0.053 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EGD94144.1 - 0.031 15.1 0.0 0.097 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 EGD94144.1 - 0.04 12.5 0.1 0.098 11.2 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 EGD94144.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGD94144.1 - 0.069 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EGD94144.1 - 0.14 11.8 0.0 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain p450 PF00067.17 EGD94147.1 - 1.3e-49 169.0 0.0 1.8e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EGD94148.1 - 4.4e-18 65.5 0.0 6.9e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD94148.1 - 8.1e-10 39.2 0.1 1.3e-08 35.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD94148.1 - 1.3e-09 37.8 0.0 1.4e-08 34.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD94148.1 - 5.8e-07 29.9 0.0 1.2e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD94148.1 - 6.8e-07 29.6 0.0 7.2e-06 26.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD94148.1 - 0.00099 19.4 0.0 0.0029 17.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGD94148.1 - 0.0048 16.3 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EGD94148.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGD94148.1 - 0.012 15.6 0.0 0.038 14.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EGD94148.1 - 0.018 14.1 0.0 0.047 12.7 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.9 EGD94148.1 - 0.045 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EGD94148.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4620 PF15399.1 EGD94149.1 - 0.05 13.7 0.1 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) ABC_membrane PF00664.18 EGD94150.1 - 3.9e-77 259.3 29.1 3.6e-40 138.1 7.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD94150.1 - 1.5e-60 203.4 0.0 3.7e-29 101.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGD94150.1 - 2e-15 56.6 6.6 1.4e-05 24.4 0.4 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGD94150.1 - 1.2e-09 37.5 1.5 0.00056 19.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EGD94150.1 - 4.3e-09 37.2 0.2 0.0058 17.4 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EGD94150.1 - 8.8e-09 35.7 4.3 0.0065 16.4 0.2 4.2 2 2 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EGD94150.1 - 1e-08 35.4 1.0 0.00079 19.5 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGD94150.1 - 2.1e-07 31.1 0.1 0.0012 18.9 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EGD94150.1 - 1.1e-06 28.2 0.2 0.013 14.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EGD94150.1 - 3.2e-06 26.4 0.3 0.1 11.8 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EGD94150.1 - 3.3e-06 27.4 0.4 0.12 12.7 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EGD94150.1 - 7.3e-06 25.6 5.3 0.22 10.9 0.1 4.1 4 0 0 4 4 4 2 AAA-like domain AAA_23 PF13476.1 EGD94150.1 - 1.2e-05 25.6 0.8 0.0034 17.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EGD94150.1 - 0.00012 20.7 2.9 0.087 11.3 0.6 3.4 3 0 0 3 3 3 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EGD94150.1 - 0.00077 19.3 0.1 0.34 10.8 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EGD94150.1 - 0.00083 19.2 0.6 0.68 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EGD94150.1 - 0.0019 17.7 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF3987 PF13148.1 EGD94150.1 - 0.0026 16.3 0.2 1.7 7.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) KaiC PF06745.8 EGD94150.1 - 0.0056 15.8 0.2 3 6.9 0.0 2.7 2 0 0 2 2 2 1 KaiC DUF87 PF01935.12 EGD94150.1 - 0.006 16.4 1.6 0.66 9.7 0.0 3.3 4 0 0 4 4 3 1 Domain of unknown function DUF87 MobB PF03205.9 EGD94150.1 - 0.0067 16.1 0.6 2.9 7.6 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EGD94150.1 - 0.0088 15.9 0.5 6.3 6.7 0.1 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.9 EGD94150.1 - 0.0091 15.7 0.2 0.79 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.15 EGD94150.1 - 0.012 15.2 1.1 6.5 6.3 0.0 3.1 3 0 0 3 3 3 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EGD94150.1 - 0.018 15.2 0.1 12 6.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EGD94150.1 - 0.02 15.1 0.0 1.2 9.3 0.0 3.4 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EGD94150.1 - 0.03 13.7 2.3 3.9 6.8 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein NACHT PF05729.7 EGD94150.1 - 0.038 13.6 0.2 23 4.6 0.0 3.3 3 0 0 3 3 3 0 NACHT domain Guanylate_kin PF00625.16 EGD94150.1 - 0.11 11.9 0.1 4.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase Zeta_toxin PF06414.7 EGD94150.1 - 0.12 11.4 0.1 15 4.6 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_14 PF13173.1 EGD94150.1 - 0.22 11.3 0.6 16 5.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.1 EGD94150.1 - 0.45 10.3 8.5 0.65 9.7 0.5 4.2 5 0 0 5 5 3 0 Part of AAA domain AAA_13 PF13166.1 EGD94150.1 - 1.7 6.9 3.0 21 3.3 0.1 2.9 3 0 0 3 3 3 0 AAA domain CbiA PF01656.18 EGD94150.1 - 3.5 6.9 4.5 27 4.0 0.1 3.0 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain MFS_1 PF07690.11 EGD94151.1 - 3.8e-30 104.8 53.0 3.8e-30 104.7 34.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 EGD94152.1 - 5.2e-45 153.8 0.0 6.3e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ric8 PF10165.4 EGD94154.1 - 1.7e-135 452.3 0.0 2.1e-135 451.9 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Polysacc_synt_4 PF04669.8 EGD94155.1 - 5.3e-25 87.8 1.5 2.9e-24 85.5 1.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Sugar_tr PF00083.19 EGD94156.1 - 2e-140 468.3 16.5 2.3e-140 468.1 11.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD94156.1 - 1.3e-27 96.4 27.2 6.9e-24 84.2 5.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EGD94156.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF2763 PF10961.3 EGD94156.1 - 1 9.8 3.9 9.9 6.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) Glyco_hydro_25 PF01183.15 EGD94157.1 - 3.8e-39 134.3 0.1 4.4e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 PsbR PF04725.7 EGD94157.1 - 0.056 13.4 0.2 0.15 12.1 0.2 1.8 1 1 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR Rif1_N PF12231.3 EGD94158.1 - 1.9e-129 431.9 0.5 1.9e-129 431.9 0.3 1.6 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal DIM PF08194.7 EGD94159.1 - 0.072 13.0 0.3 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 DIM protein S_layer_N PF05123.7 EGD94159.1 - 1.4 8.4 4.6 2.6 7.6 2.3 1.8 2 0 0 2 2 2 0 S-layer like family, N-terminal region Aldose_epim PF01263.15 EGD94160.1 - 1e-28 100.3 0.0 1.2e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase MFS_1 PF07690.11 EGD94161.1 - 2.2e-24 85.8 26.7 2.2e-24 85.8 18.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DAHP_synth_2 PF01474.11 EGD94163.1 - 1.4e-196 653.0 0.0 1.6e-196 652.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family PLA2_B PF01735.13 EGD94165.1 - 6.7e-195 647.9 0.2 7.8e-195 647.7 0.1 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF3742 PF12553.3 EGD94167.1 - 0.066 13.6 0.3 0.96 9.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) EphA2_TM PF14575.1 EGD94167.1 - 0.098 13.0 0.4 0.3 11.5 0.3 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SP_C-Propep PF08999.5 EGD94167.1 - 0.96 8.9 4.9 2.1 7.8 3.4 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF1510 PF07423.6 EGD94167.1 - 2.1 7.6 9.7 18 4.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) adh_short PF00106.20 EGD94169.1 - 7.1e-30 104.1 1.0 9e-30 103.7 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD94169.1 - 1.6e-29 103.3 0.0 1.9e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD94169.1 - 9.7e-18 64.4 0.4 1.4e-17 63.9 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD94169.1 - 0.0076 15.7 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1537 PF07005.6 EGD94169.1 - 0.02 14.5 0.4 1.5 8.4 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function, DUF1537 3H PF02829.9 EGD94169.1 - 0.13 12.2 0.1 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 3H domain Ribosomal_L18p PF00861.17 EGD94169.1 - 0.22 11.7 1.6 1.6 8.9 0.0 2.6 1 1 3 4 4 4 0 Ribosomal L18p/L5e family AIG2 PF06094.7 EGD94170.1 - 1e-10 42.0 0.2 1.4e-10 41.5 0.1 1.2 1 0 0 1 1 1 1 AIG2-like family Piwi PF02171.12 EGD94171.1 - 4.6e-71 239.2 0.0 6.7e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EGD94171.1 - 2.1e-12 46.2 0.1 4.5e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EGD94171.1 - 2e-08 33.6 0.0 4.8e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 PAZ domain Ribophorin_II PF05817.9 EGD94173.1 - 4.5e-17 61.5 1.4 7.9e-17 60.7 1.0 1.4 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF4622 PF15415.1 EGD94173.1 - 0.0056 15.5 0.0 0.0093 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4622) PufQ PF05398.6 EGD94173.1 - 0.28 11.2 1.7 3.3 7.7 0.0 2.8 3 0 0 3 3 3 0 PufQ cytochrome subunit DUF1049 PF06305.6 EGD94173.1 - 0.28 10.6 4.5 2.7 7.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) Lsm_interact PF05391.6 EGD94175.1 - 9.6 5.8 6.4 0.5 9.8 0.4 1.9 2 0 0 2 2 2 0 Lsm interaction motif EVE PF01878.13 EGD94176.1 - 2.7e-47 160.3 0.1 2.7e-47 160.3 0.1 2.2 2 1 1 3 3 3 1 EVE domain KIAA1328 PF15369.1 EGD94176.1 - 3.7 7.2 6.9 5 6.8 4.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 OCC1 PF15506.1 EGD94176.1 - 4.3 7.3 6.6 3 7.7 1.4 2.8 3 0 0 3 3 3 0 OCC1 family Methyltransf_PK PF05891.7 EGD94177.1 - 2.9e-66 222.9 0.0 4.6e-66 222.2 0.0 1.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.13 EGD94177.1 - 1.4e-07 30.9 0.0 2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGD94177.1 - 7.5e-05 23.2 0.1 0.00049 20.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD94177.1 - 0.00016 21.4 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD94177.1 - 0.0027 18.1 0.0 0.0078 16.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD94177.1 - 0.072 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EGD94177.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Aldedh PF00171.17 EGD94178.1 - 2.4e-183 609.6 3.2 2.7e-183 609.5 2.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGD94178.1 - 0.00072 18.8 0.0 0.0031 16.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Ski_Sno PF02437.12 EGD94180.1 - 0.06 12.9 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 SKI/SNO/DAC family bZIP_2 PF07716.10 EGD94181.1 - 3.3e-05 23.6 10.5 5.4e-05 22.9 7.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EGD94181.1 - 0.0064 16.4 6.3 0.013 15.4 4.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor His_Phos_2 PF00328.17 EGD94183.1 - 3.1e-53 181.3 0.0 3.6e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AhpC-TSA PF00578.16 EGD94185.1 - 7e-16 58.0 0.1 2.2e-08 33.8 0.0 2.3 1 1 1 2 2 2 2 AhpC/TSA family 1-cysPrx_C PF10417.4 EGD94185.1 - 9.6e-09 34.7 0.1 1.8e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EGD94185.1 - 0.0016 17.9 0.3 0.6 9.6 0.0 2.6 2 1 1 3 3 3 2 Redoxin Kelch_3 PF13415.1 EGD94186.1 - 7.7e-22 76.8 2.4 1.4e-10 41.0 0.0 5.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EGD94186.1 - 7.8e-19 67.1 0.9 1e-07 31.5 0.0 5.6 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EGD94186.1 - 4.3e-10 38.9 0.0 0.013 15.0 0.0 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 EGD94186.1 - 2.3e-09 37.0 2.6 0.11 12.6 0.3 5.5 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 EGD94186.1 - 2.4e-07 30.5 5.3 0.0084 16.0 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EGD94186.1 - 2.5e-05 23.8 8.7 0.0022 17.6 0.0 5.2 6 0 0 6 6 6 1 Kelch motif BTB PF00651.26 EGD94186.1 - 0.2 11.6 0.0 0.72 9.8 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain mRNA_triPase PF02940.10 EGD94187.1 - 1.2e-29 103.6 0.0 4.1e-18 65.9 0.0 2.4 1 1 1 2 2 2 2 mRNA capping enzyme, beta chain WD40 PF00400.27 EGD94188.1 - 2.4e-23 81.1 9.9 2.1e-08 33.7 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat TFIIA PF03153.8 EGD94188.1 - 2.4 7.9 21.3 4.7 6.9 14.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CTP_transf_2 PF01467.21 EGD94189.1 - 0.0004 20.4 0.9 0.28 11.2 0.2 2.5 2 1 0 2 2 2 2 Cytidylyltransferase DUF2697 PF10906.3 EGD94190.1 - 0.053 13.5 0.1 0.63 10.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2697) DUF4559 PF15112.1 EGD94190.1 - 0.15 11.2 0.3 0.19 10.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) F-box PF00646.28 EGD94192.1 - 0.087 12.5 1.3 0.24 11.0 0.1 2.3 2 0 0 2 2 2 0 F-box domain Zn_clus PF00172.13 EGD94193.1 - 2.2e-09 37.0 6.6 2.2e-09 37.0 4.6 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGD94193.1 - 8.6e-05 21.2 0.3 0.00012 20.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAM217 PF15344.1 EGD94193.1 - 0.13 11.8 0.8 0.19 11.2 0.6 1.2 1 0 0 1 1 1 0 FAM217 family UbiA PF01040.13 EGD94194.1 - 1.4e-29 103.0 19.7 1.4e-29 103.0 13.6 1.5 1 1 1 2 2 2 1 UbiA prenyltransferase family PQ-loop PF04193.9 EGD94195.1 - 5.9e-19 67.3 13.7 1.2e-12 47.2 1.1 3.1 3 0 0 3 3 3 2 PQ loop repeat DUF3464 PF11947.3 EGD94195.1 - 4.6 6.6 6.2 2.9 7.3 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Med8 PF10232.4 EGD94196.1 - 4e-40 137.7 0.7 5.1e-40 137.3 0.5 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 RCR PF12273.3 EGD94197.1 - 0.00025 21.5 0.8 0.00041 20.8 0.6 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.1 EGD94197.1 - 0.046 13.4 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.1 EGD94197.1 - 0.077 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) FAD_binding_4 PF01565.18 EGD94201.1 - 2.2e-22 79.0 0.3 3.7e-22 78.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD94201.1 - 0.012 15.4 0.0 0.071 13.0 0.0 2.2 2 0 0 2 2 2 0 Berberine and berberine like Abhydrolase_6 PF12697.2 EGD94202.1 - 1.7e-06 28.1 0.1 4.1e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD94202.1 - 1e-05 25.3 0.0 3.5e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGD94202.1 - 0.036 13.2 3.0 0.12 11.5 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EGD94202.1 - 0.037 13.8 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase TMF_TATA_bd PF12325.3 EGD94203.1 - 0.00036 20.2 7.4 0.00036 20.2 5.1 4.2 3 2 1 4 4 4 1 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 EGD94203.1 - 0.0028 16.9 2.3 0.012 14.8 0.1 2.1 2 0 0 2 2 2 1 Reovirus sigma C capsid protein IncA PF04156.9 EGD94203.1 - 0.0045 16.6 22.6 0.0052 16.4 4.1 3.1 3 0 0 3 3 3 2 IncA protein DNA_repr_REX1B PF14966.1 EGD94203.1 - 0.04 14.2 1.8 0.16 12.3 1.2 2.0 1 0 0 1 1 1 0 DNA repair REX1-B Spc7 PF08317.6 EGD94203.1 - 0.043 12.4 18.8 0.15 10.6 6.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3053 PF11254.3 EGD94203.1 - 0.12 11.6 4.6 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) DUF2730 PF10805.3 EGD94203.1 - 0.27 10.9 6.7 0.074 12.7 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Rbsn PF11464.3 EGD94203.1 - 0.31 10.6 5.2 0.14 11.7 0.2 2.7 2 0 0 2 2 2 0 Rabenosyn Rab binding domain Med4 PF10018.4 EGD94203.1 - 0.35 10.2 14.0 0.019 14.3 3.0 2.9 3 0 0 3 3 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3461 PF11944.3 EGD94203.1 - 0.67 9.7 7.6 0.25 11.1 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) Mod_r PF07200.8 EGD94203.1 - 0.9 9.4 20.4 0.2 11.5 4.2 3.9 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein MutS_IV PF05190.13 EGD94203.1 - 0.98 9.6 9.1 4.3 7.5 0.4 4.2 4 0 0 4 4 4 0 MutS family domain IV Seryl_tRNA_N PF02403.17 EGD94203.1 - 1.1 9.3 21.6 0.18 11.7 4.3 4.2 3 2 2 5 5 5 0 Seryl-tRNA synthetase N-terminal domain CorA PF01544.13 EGD94203.1 - 1.1 8.2 5.0 0.49 9.3 0.5 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1515 PF07439.6 EGD94203.1 - 1.4 8.7 10.0 0.084 12.6 1.9 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Nup54 PF13874.1 EGD94203.1 - 2.2 7.9 15.2 1.1 8.9 3.2 3.3 2 2 2 4 4 4 0 Nucleoporin complex subunit 54 Syntaxin-6_N PF09177.6 EGD94203.1 - 2.7 8.4 14.6 1.9 8.9 0.4 3.3 3 1 0 3 3 2 0 Syntaxin 6, N-terminal DUF342 PF03961.8 EGD94203.1 - 3.2 6.0 14.2 4.3 5.6 4.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) FliD_N PF02465.13 EGD94203.1 - 3.8 7.9 9.0 3.9 7.9 0.1 4.1 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 N-terminus DUF465 PF04325.8 EGD94203.1 - 4 7.2 10.9 0.86 9.3 2.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Allexi_40kDa PF05549.6 EGD94203.1 - 4.1 6.6 12.7 0.16 11.2 1.0 3.0 3 0 0 3 3 3 0 Allexivirus 40kDa protein DUF724 PF05266.9 EGD94203.1 - 4.9 6.7 16.0 0.56 9.7 4.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF724) SPX PF03105.14 EGD94203.1 - 6.2 6.5 12.1 22 4.7 8.4 2.0 1 1 0 1 1 1 0 SPX domain HR1 PF02185.11 EGD94203.1 - 6.3 6.6 16.4 2.3 8.0 2.7 3.8 3 1 1 4 4 4 0 Hr1 repeat DUF1664 PF07889.7 EGD94203.1 - 7.9 6.3 10.4 2 8.2 1.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PC_rep PF01851.17 EGD94204.1 - 1.7e-35 119.2 21.7 2.4e-09 36.9 0.0 9.9 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EGD94204.1 - 2.3e-19 69.4 0.5 8.7e-14 51.5 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EGD94204.1 - 1.3e-09 38.2 0.3 5.6e-06 26.6 0.0 4.3 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EGD94204.1 - 2e-08 33.5 0.1 1.1 9.4 0.0 5.2 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.11 EGD94204.1 - 0.0063 16.8 2.3 0.88 10.2 0.0 3.9 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat CDC45 PF02724.9 EGD94204.1 - 2.3 6.1 11.2 4.7 5.1 7.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.6 EGD94204.1 - 9.8 4.7 13.7 0.08 11.6 3.7 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Acyl-CoA_dh_1 PF00441.19 EGD94205.1 - 3.4e-41 140.8 0.4 5.5e-41 140.1 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGD94205.1 - 7e-20 70.2 0.1 1.2e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EGD94205.1 - 7.8e-18 65.0 0.0 1.8e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 EGD94205.1 - 3.9e-15 55.4 0.4 7.5e-15 54.5 0.3 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 EGD94205.1 - 5.1e-08 33.2 0.1 8.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CTD PF12815.2 EGD94206.1 - 3.6e-23 82.2 48.7 3.1e-22 79.2 21.9 3.6 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 EGD94206.1 - 2.1e-22 78.6 0.0 3.8e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EGD94206.1 - 2.2e-17 63.4 11.2 2.2e-17 63.4 7.8 3.8 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EGD94206.1 - 0.00018 21.1 12.6 0.011 15.4 1.1 4.1 4 0 0 4 4 4 2 KOW motif DUF1506 PF07405.6 EGD94206.1 - 0.081 12.9 0.2 1 9.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1506) CS PF04969.11 EGD94207.1 - 5.3e-08 33.2 0.0 6.6e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 CS domain Anoctamin PF04547.7 EGD94208.1 - 3.1e-115 385.4 8.3 3.8e-115 385.1 5.7 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Pex2_Pex12 PF04757.9 EGD94208.1 - 0.00091 18.7 0.0 0.0031 16.9 0.0 1.9 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region YMF19 PF02326.10 EGD94208.1 - 0.55 10.8 3.7 12 6.5 0.6 3.5 3 0 0 3 3 3 0 Plant ATP synthase F0 APH PF01636.18 EGD94209.1 - 2.8e-05 23.9 0.1 2.8e-05 23.9 0.1 3.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.1 EGD94209.1 - 0.00027 20.7 0.0 0.61 9.8 0.0 2.5 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.15 EGD94209.1 - 0.0021 17.6 1.2 0.0043 16.6 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase ERM PF00769.14 EGD94209.1 - 0.0025 17.3 28.2 0.0025 17.3 19.6 1.7 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Pkinase PF00069.20 EGD94209.1 - 0.055 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain APG6 PF04111.7 EGD94209.1 - 3.3 6.6 25.4 5.2 6.0 17.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Actin PF00022.14 EGD94211.1 - 1.3e-56 191.6 0.0 2.9e-32 111.5 0.0 2.2 2 0 0 2 2 2 2 Actin DASH_Dad4 PF08650.5 EGD94212.1 - 5.2e-29 99.9 4.8 6e-29 99.7 3.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 EGD94212.1 - 0.0078 15.8 1.7 0.01 15.5 1.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 GM_CSF PF01109.12 EGD94212.1 - 0.0082 16.0 0.4 0.011 15.7 0.3 1.2 1 0 0 1 1 1 1 Granulocyte-macrophage colony-stimulating factor DUF2443 PF10398.4 EGD94212.1 - 0.028 14.2 0.5 0.046 13.5 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2443) NHR2 PF08788.6 EGD94212.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 NHR2 domain like YL1_C PF08265.6 EGD94213.1 - 2.8e-17 61.9 0.2 4.9e-17 61.1 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Pol_alpha_B_N PF08418.5 EGD94213.1 - 0.24 10.8 4.5 0.31 10.5 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Got1 PF04178.7 EGD94214.1 - 1e-19 70.7 14.2 1.2e-19 70.5 9.9 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1616 PF07760.6 EGD94214.1 - 7.4 5.6 8.7 8.7 5.3 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Profilin PF00235.14 EGD94215.1 - 2.1e-39 134.3 0.0 2.4e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Profilin Sec63 PF02889.11 EGD94218.1 - 3.8e-149 496.1 0.0 3e-92 309.1 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EGD94218.1 - 1.1e-54 184.4 1.4 2.5e-28 98.6 1.1 3.1 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EGD94218.1 - 6.5e-17 61.9 0.0 7.9e-08 32.3 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGD94218.1 - 6e-16 58.0 0.0 3e-07 30.1 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGD94218.1 - 1.5e-07 31.5 1.6 0.0098 16.0 0.0 3.5 3 1 0 3 3 2 2 AAA domain SNF2_N PF00176.18 EGD94218.1 - 0.00037 19.3 0.5 0.21 10.3 0.1 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain PhoH PF02562.11 EGD94218.1 - 0.0018 17.5 0.0 0.51 9.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein FtsK_SpoIIIE PF01580.13 EGD94218.1 - 0.0027 17.2 0.6 0.029 13.8 0.2 2.7 2 1 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 EGD94218.1 - 0.0031 16.4 0.0 0.9 8.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein IstB_IS21 PF01695.12 EGD94218.1 - 0.011 15.1 0.0 5 6.4 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_10 PF12846.2 EGD94218.1 - 0.02 14.3 0.0 6.1 6.1 0.0 3.8 3 1 0 4 4 4 0 AAA-like domain AAA_25 PF13481.1 EGD94218.1 - 0.085 12.2 0.4 1.3 8.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain Longin PF13774.1 EGD94219.1 - 4.1e-14 51.9 0.0 6.4e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EGD94219.1 - 7.1e-14 51.1 0.2 1.1e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 EGD94219.1 - 0.019 14.7 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Pkinase PF00069.20 EGD94221.1 - 1.6e-25 89.7 0.0 3e-25 88.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94221.1 - 4.3e-05 22.7 0.3 0.053 12.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase MFS_1 PF07690.11 EGD94222.1 - 2.2e-24 85.8 70.6 6.6e-18 64.5 30.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGD94222.1 - 3.7e-06 26.8 15.9 0.061 13.3 2.6 4.0 4 1 1 5 5 5 3 Protein of unknown function (DUF1228) Ras PF00071.17 EGD94223.1 - 7.1e-36 123.0 0.0 7.7e-35 119.6 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGD94223.1 - 7.6e-16 58.6 0.0 1.4e-15 57.8 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD94223.1 - 2.3e-10 39.9 0.0 3.6e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.1 EGD94223.1 - 0.00072 19.5 0.1 0.007 16.3 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGD94223.1 - 0.0022 18.1 0.0 0.005 16.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EGD94223.1 - 0.0027 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGD94223.1 - 0.0037 17.2 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGD94223.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EGD94223.1 - 0.032 13.6 0.0 0.42 10.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EGD94223.1 - 0.052 12.7 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EGD94223.1 - 0.055 13.1 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 EGD94223.1 - 0.059 13.3 0.2 0.13 12.1 0.1 1.7 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 EGD94223.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EGD94223.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EGD94223.1 - 0.14 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain FMN_dh PF01070.13 EGD94224.1 - 1.3e-120 402.4 0.2 1.6e-120 402.2 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EGD94224.1 - 9.5e-21 73.3 0.0 1.8e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EGD94224.1 - 6.6e-06 25.2 0.0 1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EGD94224.1 - 1.5e-05 24.3 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGD94224.1 - 0.0026 16.7 2.0 0.0043 15.9 0.1 2.2 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EGD94224.1 - 0.0098 15.1 0.0 0.94 8.6 0.0 2.3 2 0 0 2 2 2 2 Histidine biosynthesis protein Metallophos PF00149.23 EGD94225.1 - 6.3e-11 42.0 6.2 1.3e-09 37.7 4.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD94225.1 - 1e-09 38.4 0.1 3.1e-09 36.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.1 EGD94225.1 - 0.22 9.7 0.0 0.32 9.2 0.0 1.1 1 0 0 1 1 1 0 MutL protein Pkinase PF00069.20 EGD94226.1 - 3.2e-40 137.9 0.1 4.2e-25 88.3 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94226.1 - 3e-13 49.4 0.0 7.6e-10 38.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Bud13 PF09736.4 EGD94227.1 - 3.2e-45 153.9 0.7 3.2e-45 153.9 0.5 3.0 2 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex PEP-utilisers_N PF05524.8 EGD94228.1 - 0.0059 16.3 0.1 0.0091 15.7 0.1 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal HAUS5 PF14817.1 EGD94228.1 - 0.018 13.5 0.5 0.024 13.1 0.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 FlaC_arch PF05377.6 EGD94228.1 - 0.052 13.4 0.7 0.12 12.2 0.5 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.6 EGD94228.1 - 0.11 12.3 2.9 0.21 11.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Bap31 PF05529.7 EGD94228.1 - 0.14 11.5 0.2 0.19 11.1 0.2 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DNA_binding_1 PF01035.15 EGD94229.1 - 1.3e-22 79.3 0.1 1.7e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Fungal_trans_2 PF11951.3 EGD94233.1 - 1.6e-96 323.2 1.7 1.8e-96 323.0 1.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD94233.1 - 7.3e-11 41.7 10.0 7.3e-11 41.7 6.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brr6_like_C_C PF10104.4 EGD94234.1 - 2.6e-44 150.0 0.5 3.4e-44 149.6 0.3 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Ninjurin PF04923.7 EGD94234.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ninjurin Nucleo_P87 PF07267.6 EGD94234.1 - 3.5 6.1 5.6 5.1 5.6 3.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AA_permease PF00324.16 EGD94235.1 - 3e-116 388.6 51.1 3.6e-116 388.3 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD94235.1 - 1.7e-30 105.9 53.5 2.2e-30 105.5 37.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD94236.1 - 2.4e-58 197.7 50.4 2.9e-58 197.4 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD94236.1 - 4.4e-11 41.7 45.7 5.8e-11 41.4 31.7 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.19 EGD94238.1 - 4.2e-16 58.7 0.0 5.9e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EGD94238.1 - 2.8e-08 34.0 0.0 3.3e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD94238.1 - 5.9e-08 32.3 0.0 9e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EGD94238.1 - 8.5e-08 32.2 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD94238.1 - 3.1e-05 24.0 0.0 5.3e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGD94238.1 - 0.0014 18.6 0.0 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD94238.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EGD94238.1 - 0.042 13.7 0.0 0.071 12.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GRIP PF01465.15 EGD94239.1 - 2.4e-15 55.7 0.2 4.9e-15 54.7 0.2 1.6 1 0 0 1 1 1 1 GRIP domain Reo_sigmaC PF04582.7 EGD94239.1 - 0.00075 18.7 56.7 0.05 12.7 5.8 7.0 4 2 3 7 7 7 5 Reovirus sigma C capsid protein Spc7 PF08317.6 EGD94239.1 - 0.0011 17.6 122.3 0.0084 14.7 10.7 7.4 3 2 4 7 7 7 4 Spc7 kinetochore protein MscS_porin PF12795.2 EGD94239.1 - 0.0055 16.0 16.2 0.0055 16.0 11.2 8.2 5 2 1 7 7 7 2 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.4 EGD94239.1 - 0.012 15.5 148.7 0.13 12.0 11.2 9.4 3 2 7 10 10 10 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 EGD94239.1 - 0.032 12.6 107.9 0.094 11.1 13.5 6.5 2 1 4 6 6 6 0 AAA domain IncA PF04156.9 EGD94239.1 - 0.038 13.5 149.3 0.065 12.8 11.7 9.7 3 3 5 8 8 7 0 IncA protein AATF-Che1 PF13339.1 EGD94239.1 - 0.043 13.9 0.5 0.043 13.9 0.3 9.6 4 2 4 8 8 6 0 Apoptosis antagonizing transcription factor Myosin_tail_1 PF01576.14 EGD94239.1 - 0.083 10.5 147.4 0.011 13.5 15.3 6.4 3 2 3 6 6 6 0 Myosin tail Filament PF00038.16 EGD94239.1 - 0.39 10.1 125.5 0.11 11.9 9.6 7.2 3 2 3 6 6 6 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 EGD94239.1 - 0.5 10.1 132.3 0.17 11.5 7.6 10.7 2 2 5 8 8 8 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.7 EGD94239.1 - 4.7 6.9 99.3 0.041 13.6 0.7 10.9 5 3 4 10 10 9 0 Plant protein of unknown function (DUF641) DUF4140 PF13600.1 EGD94239.1 - 7.3 7.1 0.0 7.3 7.1 0.0 15.1 6 2 8 15 15 12 0 N-terminal domain of unknown function (DUF4140) DUF2296 PF10058.4 EGD94240.1 - 9.8e-19 66.8 0.1 1.6e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) cNMP_binding PF00027.24 EGD94241.1 - 5.8e-42 141.4 0.1 9.6e-23 79.8 0.0 4.5 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EGD94241.1 - 9.3e-18 64.8 10.5 2.2e-17 63.6 4.7 2.9 2 1 0 2 2 2 1 Patatin-like phospholipase DAO PF01266.19 EGD94242.1 - 1.3e-41 142.7 0.0 1.5e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGD94242.1 - 0.00043 20.0 0.0 0.028 14.1 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGD94242.1 - 0.00086 19.2 0.0 0.56 10.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EGD94242.1 - 0.0017 17.4 0.0 0.0031 16.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_8 PF13450.1 EGD94242.1 - 0.0022 17.9 0.0 0.0067 16.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGD94242.1 - 0.027 14.5 0.0 8.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.2 EGD94242.1 - 0.027 14.3 0.1 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_33 PF10017.4 EGD94243.1 - 7.2e-23 80.8 0.0 1.4e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 EGD94243.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.3 EGD94244.1 - 4.5e-28 97.9 0.3 6.4e-28 97.4 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIB PF00382.14 EGD94244.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat zf-C2H2_4 PF13894.1 EGD94245.1 - 0.00011 22.2 1.6 0.23 11.8 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger HNH_2 PF13391.1 EGD94246.1 - 2.8e-05 23.7 0.0 8e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 HNH endonuclease ISN1 PF06437.6 EGD94247.1 - 6.6e-189 627.8 0.0 7.5e-189 627.6 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase eIF-5a PF01287.15 EGD94247.1 - 0.019 14.9 0.0 0.056 13.4 0.0 1.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RasGEF_N_2 PF14663.1 EGD94247.1 - 0.055 13.4 0.2 0.4 10.6 0.1 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Med17 PF10156.4 EGD94248.1 - 3.2e-116 388.3 2.3 3.9e-116 388.0 1.6 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.15 EGD94249.1 - 7e-170 563.2 0.1 4.2e-123 409.8 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase NAD_kinase PF01513.16 EGD94249.1 - 0.12 11.1 0.2 0.55 8.9 0.1 1.9 2 0 0 2 2 2 0 ATP-NAD kinase Glyco_hydro_76 PF03663.9 EGD94250.1 - 3.5e-155 516.9 7.6 4.3e-155 516.6 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EGD94250.1 - 0.00063 18.8 7.3 0.0042 16.1 0.0 3.1 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 MARVEL PF01284.18 EGD94251.1 - 1.3e-10 41.2 9.5 1.7e-10 40.9 6.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DnaJ PF00226.26 EGD94252.1 - 6.2e-05 22.6 0.0 0.00035 20.2 0.0 2.3 1 0 0 1 1 1 1 DnaJ domain OmpH PF03938.9 EGD94252.1 - 4.2 7.2 17.9 6.7 6.6 12.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Neur_chan_memb PF02932.11 EGD94252.1 - 4.2 7.1 8.4 6.9 6.4 5.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RRM_5 PF13893.1 EGD94253.1 - 3.8e-11 42.6 0.0 1e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD94253.1 - 2e-10 40.1 0.0 3.7e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD94253.1 - 1.5e-06 28.0 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD94253.1 - 0.0035 17.0 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.5 EGD94254.1 - 5.3e-28 96.7 0.1 8e-28 96.1 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EGD94254.1 - 3.2e-18 65.9 0.0 5.8e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD94254.1 - 1.9e-16 60.0 0.0 2.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD94254.1 - 1.9e-14 53.7 0.0 3.1e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD94254.1 - 6.6e-13 48.8 0.0 1.3e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD94254.1 - 3.9e-11 43.5 0.0 9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGD94254.1 - 4.4e-11 42.3 0.0 6.6e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EGD94254.1 - 5.4e-11 42.8 0.0 1.2e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD94254.1 - 2.2e-09 36.7 0.0 3.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGD94254.1 - 4e-09 36.5 0.0 9.8e-09 35.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EGD94254.1 - 5e-05 22.9 0.0 7.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EGD94254.1 - 7.2e-05 22.2 0.0 0.00035 19.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 EGD94254.1 - 0.00093 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EGD94254.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EGD94254.1 - 0.0071 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EGD94254.1 - 0.01 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 EGD94254.1 - 0.024 13.7 0.0 0.07 12.1 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_24 PF13578.1 EGD94254.1 - 0.037 14.8 0.0 0.12 13.1 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EGD94254.1 - 0.084 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Met_10 PF02475.11 EGD94254.1 - 0.12 11.8 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein zf-MYND PF01753.13 EGD94255.1 - 7.8e-08 32.0 10.7 7.8e-08 32.0 7.4 2.0 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EGD94255.1 - 1.4 8.6 15.0 0.19 11.4 6.5 2.4 2 0 0 2 2 2 0 HIT zinc finger Peptidase_S8 PF00082.17 EGD94256.1 - 5.1e-32 111.1 11.3 9.3e-32 110.2 7.8 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD94256.1 - 8.8e-15 55.0 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 MFS_1 PF07690.11 EGD94257.1 - 5.5e-44 150.3 52.2 6.1e-43 146.8 36.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD94257.1 - 2.3e-07 29.7 9.8 2.3e-07 29.7 6.8 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter DUF3377 PF11857.3 EGD94257.1 - 0.066 12.8 0.1 0.35 10.5 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) WTF PF03303.8 EGD94257.1 - 0.084 12.2 5.5 0.19 11.0 3.8 1.7 1 0 0 1 1 1 0 WTF protein Zn_clus PF00172.13 EGD94258.1 - 1.7e-08 34.2 9.3 3e-08 33.4 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.18 EGD94259.1 - 2.6e-51 174.6 0.0 1e-49 169.4 0.0 2.1 1 1 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EGD94259.1 - 7.2e-21 73.7 0.2 3.8e-20 71.4 0.0 2.2 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EGD94259.1 - 5.6e-08 32.4 1.2 0.00036 19.9 0.6 2.3 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EGD94259.1 - 0.02 15.1 0.0 0.056 13.7 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Tox-HDC PF15656.1 EGD94259.1 - 0.062 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature DUF229 PF02995.12 EGD94259.1 - 0.077 11.4 0.0 0.097 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Peptidase_C16 PF01831.12 EGD94259.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C16 family Amidohydro_1 PF01979.15 EGD94260.1 - 3.3e-39 135.4 0.0 4e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EGD94260.1 - 6.7e-07 28.8 0.0 0.00026 20.3 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family A_deaminase PF00962.17 EGD94260.1 - 3.1e-06 26.3 0.0 4.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 EGD94260.1 - 0.0017 18.4 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EGD94260.1 - 0.0027 17.4 0.0 0.0085 15.8 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Toxin_29 PF08116.6 EGD94260.1 - 0.029 14.1 0.3 0.086 12.6 0.2 1.8 1 0 0 1 1 1 0 PhTx neurotoxin family GDC-P PF02347.11 EGD94264.1 - 2.1e-170 567.0 0.0 2.6e-158 527.2 0.0 2.8 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EGD94264.1 - 5.3e-08 32.3 0.1 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGD94264.1 - 0.00056 18.7 0.1 0.0037 16.0 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_3 PF00202.16 EGD94264.1 - 0.011 14.6 0.0 0.021 13.6 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.12 EGD94264.1 - 0.023 13.7 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TMEM51 PF15345.1 EGD94265.1 - 9.8e-05 22.1 3.3 0.00012 21.9 1.4 1.9 1 1 0 1 1 1 1 Transmembrane protein 51 Pyridoxal_deC PF00282.14 EGD94266.1 - 2.6e-115 384.8 0.0 3.1e-115 384.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EGD94266.1 - 0.0027 16.8 0.0 0.0055 15.8 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Abhydrolase_6 PF12697.2 EGD94267.1 - 1.9e-19 70.4 0.1 2.2e-19 70.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD94267.1 - 5.6e-11 42.3 0.2 8e-11 41.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EGD94267.1 - 0.045 13.3 0.0 0.29 10.7 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase MBOAT_2 PF13813.1 EGD94268.1 - 2.2e-22 78.9 0.3 4.3e-22 77.9 0.2 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Glyco_hydro_65m PF03632.10 EGD94269.1 - 5.4e-82 275.4 1.1 3e-81 272.9 0.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EGD94269.1 - 1.5e-46 158.7 0.0 2.4e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 EGD94269.1 - 0.00018 21.5 0.4 0.00049 20.1 0.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain SMC_Nse1 PF07574.8 EGD94270.1 - 1.4e-40 139.1 0.0 1.7e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EGD94270.1 - 8.2e-11 41.7 9.3 1.6e-10 40.8 6.5 1.5 1 0 0 1 1 1 1 RING-like domain PaaX PF07848.7 EGD94270.1 - 0.0024 17.8 0.1 0.0064 16.4 0.1 1.7 1 0 0 1 1 1 1 PaaX-like protein zf-rbx1 PF12678.2 EGD94270.1 - 0.0041 17.1 2.8 0.007 16.4 2.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGD94270.1 - 0.0054 16.5 7.9 0.0095 15.7 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 EGD94270.1 - 0.0085 15.9 2.1 0.015 15.0 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Mrr_N PF14338.1 EGD94270.1 - 0.095 12.7 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Mrr N-terminal domain zf-HC5HC2H_2 PF13832.1 EGD94270.1 - 0.28 11.2 7.9 1.1 9.2 5.6 1.9 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 EGD94270.1 - 0.5 10.1 9.7 0.88 9.3 6.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Baculo_IE-1 PF05290.6 EGD94270.1 - 0.56 9.9 4.4 1.2 8.8 2.5 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 EGD94270.1 - 1.5 8.5 8.0 3 7.5 5.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 EGD94270.1 - 4.9 7.3 10.9 15 5.7 6.8 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain DAO PF01266.19 EGD94271.1 - 3.1e-38 131.5 0.6 4e-38 131.2 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGD94271.1 - 0.0041 17.4 0.0 0.047 14.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD94271.1 - 0.0073 16.3 0.1 0.017 15.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGD94271.1 - 0.011 15.6 0.0 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD94271.1 - 0.017 14.9 0.1 0.037 13.8 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF4066 PF13278.1 EGD94272.1 - 2.6e-32 111.3 0.0 3.3e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EGD94272.1 - 8.8e-17 60.9 0.0 1.2e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EGD94272.1 - 0.0003 20.3 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I APH PF01636.18 EGD94273.1 - 3e-12 46.8 0.0 1.1e-06 28.5 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family APH PF01636.18 EGD94274.1 - 5.4e-11 42.6 0.0 1.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD94274.1 - 1e-05 25.2 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGD94274.1 - 0.00034 19.8 0.0 0.24 10.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain CBM_19 PF03427.8 EGD94274.1 - 0.021 14.5 0.2 0.067 12.9 0.0 1.8 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) Fructosamin_kin PF03881.9 EGD94274.1 - 0.026 13.5 0.0 4.5 6.1 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase DUF1679 PF07914.6 EGD94274.1 - 0.075 11.6 0.1 2.1 6.8 0.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) AA_permease_2 PF13520.1 EGD94275.1 - 9.5e-69 231.9 31.5 1.2e-68 231.6 21.8 1.1 1 0 0 1 1 1 1 Amino acid permease DAP10 PF07213.6 EGD94275.1 - 0.058 13.1 1.4 1.3 8.8 0.3 2.6 2 0 0 2 2 2 0 DAP10 membrane protein IncA PF04156.9 EGD94275.1 - 0.28 10.7 1.7 0.98 8.9 1.2 1.9 1 0 0 1 1 1 0 IncA protein adh_short PF00106.20 EGD94276.1 - 3.6e-30 105.0 0.1 4.9e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD94276.1 - 1.7e-13 50.9 0.0 2.3e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD94276.1 - 2.6e-10 40.2 0.0 3.6e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD94276.1 - 2.7e-05 23.7 0.0 8.8e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EGD94276.1 - 0.00015 21.7 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 EGD94276.1 - 0.00018 21.6 0.0 0.00027 20.9 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGD94276.1 - 0.0057 15.3 0.0 0.008 14.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EGD94276.1 - 0.06 12.6 0.1 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family CBFD_NFYB_HMF PF00808.18 EGD94277.1 - 8.7e-19 67.3 0.5 1.5e-18 66.5 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGD94277.1 - 0.00073 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EGD94277.1 - 0.097 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated YolD PF08863.5 EGD94277.1 - 0.69 9.7 2.8 0.46 10.3 0.7 1.6 2 0 0 2 2 2 0 YolD-like protein Actin PF00022.14 EGD94278.1 - 1.6e-21 76.2 0.0 9.4e-20 70.3 0.0 2.7 2 1 0 2 2 2 1 Actin Methyltransf_32 PF13679.1 EGD94278.1 - 0.06 13.0 1.6 6.5 6.4 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain DDHD PF02862.12 EGD94278.1 - 0.5 10.1 2.5 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 DDHD domain Bystin PF05291.6 EGD94279.1 - 2.8e-126 420.5 0.0 4.1e-126 419.9 0.0 1.2 1 0 0 1 1 1 1 Bystin SPRY PF00622.23 EGD94280.1 - 0.00055 20.0 0.0 0.0035 17.4 0.0 2.3 3 0 0 3 3 3 1 SPRY domain Amidase PF01425.16 EGD94281.1 - 1.5e-114 383.2 0.1 2.6e-114 382.5 0.1 1.3 1 1 0 1 1 1 1 Amidase Snf7 PF03357.16 EGD94282.1 - 0.00029 20.2 8.1 0.00038 19.8 5.6 1.1 1 0 0 1 1 1 1 Snf7 DUF3829 PF12889.2 EGD94282.1 - 0.01 15.0 5.4 0.014 14.6 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) DUF4169 PF13770.1 EGD94282.1 - 0.25 11.3 6.8 0.12 12.3 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) bZIP_2 PF07716.10 EGD94284.1 - 1.8e-08 34.0 14.2 1.8e-08 34.0 9.9 2.7 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EGD94284.1 - 3.1e-05 23.8 16.9 0.00017 21.4 11.7 2.3 1 1 0 1 1 1 1 bZIP transcription factor Striatin PF08232.7 EGD94284.1 - 0.00021 21.5 8.2 0.00025 21.3 4.7 1.8 1 1 0 1 1 1 1 Striatin family bZIP_Maf PF03131.12 EGD94284.1 - 0.0098 16.1 11.9 0.0098 16.1 8.3 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF869 PF05911.6 EGD94284.1 - 0.012 13.9 5.8 0.019 13.2 4.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) CENP-H PF05837.7 EGD94284.1 - 0.027 14.6 2.5 0.027 14.6 1.7 2.2 1 1 0 2 2 2 0 Centromere protein H (CENP-H) APG6 PF04111.7 EGD94284.1 - 0.19 10.7 8.7 0.29 10.1 6.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.1 EGD94284.1 - 0.69 9.0 7.5 1.2 8.3 5.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 APH PF01636.18 EGD94286.1 - 2e-08 34.2 0.0 6e-08 32.7 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGD94286.1 - 0.00058 18.6 0.0 0.014 14.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Mvb12 PF09452.5 EGD94286.1 - 0.022 14.9 0.2 0.055 13.6 0.1 1.7 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 Fructosamin_kin PF03881.9 EGD94286.1 - 0.037 13.0 0.0 0.97 8.3 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Choline_kinase PF01633.15 EGD94286.1 - 0.056 13.0 0.2 15 5.0 0.0 3.0 3 0 0 3 3 3 0 Choline/ethanolamine kinase ADH_zinc_N PF00107.21 EGD94287.1 - 2e-11 43.5 0.0 5.4e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD94287.1 - 0.005 16.5 0.0 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EGD94287.1 - 0.0065 16.3 0.2 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD94287.1 - 0.0081 15.8 0.2 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Metallophos PF00149.23 EGD94288.1 - 1.7e-09 37.3 0.2 2.7e-09 36.7 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EGD94288.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain TetM_leader PF08076.6 EGD94288.1 - 0.077 12.5 1.2 0.21 11.1 0.8 1.7 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide Transket_pyr PF02779.19 EGD94289.1 - 4e-47 159.9 0.0 7e-47 159.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGD94289.1 - 1.4e-35 121.8 0.1 4.3e-35 120.3 0.1 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Glyco_hydro_43 PF04616.9 EGD94290.1 - 1.1e-59 201.8 3.6 1.3e-59 201.6 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 zf-C2H2 PF00096.21 EGD94291.1 - 0.0054 16.9 1.2 0.012 15.9 0.8 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 EGD94291.1 - 0.007 16.5 0.3 0.012 15.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EGD94291.1 - 0.012 15.9 0.4 0.027 14.8 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger UPF0240 PF06784.6 EGD94291.1 - 0.049 13.3 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) zf-C2H2_jaz PF12171.3 EGD94291.1 - 0.055 13.6 2.7 0.095 12.8 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGD94291.1 - 0.098 12.7 0.2 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EGD94291.1 - 0.11 12.3 0.2 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M48 PF01435.13 EGD94291.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M48 DUF1691 PF07950.6 EGD94292.1 - 1.5e-46 156.8 5.0 4.1e-31 107.1 2.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) TRM PF02005.11 EGD94293.1 - 6.7e-107 357.6 0.0 7e-92 308.2 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 EGD94293.1 - 0.00048 20.1 0.1 0.0013 18.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD94293.1 - 0.0007 19.2 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD94293.1 - 0.0034 17.9 0.0 0.0067 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGD94293.1 - 0.047 13.2 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.9 EGD94293.1 - 0.12 11.7 0.0 0.34 10.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain ketoacyl-synt PF00109.21 EGD94294.1 - 1.4e-19 70.5 0.0 2.8e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EGD94294.1 - 1.5e-19 70.7 0.0 3.6e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EGD94294.1 - 2e-18 66.2 0.1 4.2e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EGD94294.1 - 8.1e-12 45.0 0.0 2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EGD94294.1 - 9.8e-05 22.3 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD94294.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 KR domain Acyl_transf_1 PF00698.16 EGD94295.1 - 1.3e-86 290.8 0.0 5.3e-83 278.9 0.0 3.8 3 1 0 3 3 3 2 Acyl transferase domain MaoC_dehydratas PF01575.14 EGD94295.1 - 5.9e-40 135.4 0.1 3.4e-39 132.9 0.0 2.2 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 EGD94295.1 - 1.1e-31 108.3 0.6 2.8e-31 107.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EGD94295.1 - 1.2e-20 73.6 0.0 4.3e-20 71.8 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EGD94295.1 - 0.00034 19.8 0.2 0.03 13.4 0.0 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase SLR1-BP PF07333.7 EGD94296.1 - 0.0022 18.1 4.7 0.0026 17.9 3.3 1.1 1 0 0 1 1 1 1 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Gamma-thionin PF00304.15 EGD94296.1 - 0.0027 17.7 6.6 0.0032 17.4 4.5 1.1 1 0 0 1 1 1 1 Gamma-thionin family Myticin-prepro PF10690.4 EGD94296.1 - 0.025 14.5 3.5 0.029 14.4 2.4 1.0 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel DUF3586 PF12131.3 EGD94296.1 - 0.061 13.3 4.7 0.079 13.0 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) Toxin_17 PF08086.6 EGD94296.1 - 0.39 10.8 8.2 0.72 9.9 5.7 1.5 1 1 0 1 1 1 0 Ergtoxin family Toxin_3 PF00537.13 EGD94296.1 - 0.53 10.1 7.7 0.74 9.7 5.3 1.2 1 0 0 1 1 1 0 Scorpion toxin-like domain Defensin_2 PF01097.13 EGD94296.1 - 0.77 9.5 10.8 1.3 8.8 7.5 1.4 1 1 0 1 1 1 0 Arthropod defensin His_Phos_2 PF00328.17 EGD94297.1 - 1.2e-114 383.3 0.0 1.5e-114 382.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EGD94297.1 - 4.8e-05 22.9 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 EGD94298.1 - 5e-82 274.5 0.1 7.2e-82 274.0 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EGD94298.1 - 1.3e-19 69.2 27.1 0.00031 20.4 0.2 10.5 12 0 0 12 12 12 5 WD domain, G-beta repeat Nup160 PF11715.3 EGD94298.1 - 0.0052 14.9 1.1 1.8 6.6 0.6 3.1 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 EGD94298.1 - 0.031 13.7 0.1 16 5.0 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.5 EGD94298.1 - 0.13 10.7 0.2 0.35 9.2 0.0 1.8 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal P_proprotein PF01483.15 EGD94298.1 - 0.17 11.6 1.4 3 7.6 0.4 2.8 3 0 0 3 3 3 0 Proprotein convertase P-domain DUF383 PF04063.9 EGD94300.1 - 1.2e-72 243.5 0.2 8.7e-72 240.7 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EGD94300.1 - 2.2e-21 75.1 1.0 8.1e-21 73.3 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF384) ArgJ PF01960.13 EGD94300.1 - 0.064 11.6 0.1 0.1 10.9 0.1 1.2 1 0 0 1 1 1 0 ArgJ family Rep-A_N PF04057.7 EGD94301.1 - 0.0014 18.3 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain TPP1 PF10341.4 EGD94301.1 - 0.022 14.7 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD PAP_assoc PF03828.14 EGD94302.1 - 7.8e-08 32.1 0.0 1.9e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase TFIIF_alpha PF05793.7 EGD94303.1 - 8.6e-09 34.2 10.6 8.6e-09 34.2 7.3 3.5 1 1 2 3 3 3 3 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IBR PF01485.16 EGD94304.1 - 2.6e-11 43.1 42.9 1.6e-07 31.0 6.7 3.8 3 1 0 3 3 3 2 IBR domain XPG_I_2 PF12813.2 EGD94305.1 - 8.2e-70 235.0 0.0 1.2e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing Inositol_P PF00459.20 EGD94306.1 - 2.6e-68 230.2 0.0 3.1e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF676 PF05057.9 EGD94307.1 - 1.8e-37 128.7 0.0 8.4e-36 123.3 0.0 2.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DAGK_cat PF00781.19 EGD94307.1 - 2.3e-11 43.2 0.0 6.1e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Abhydrolase_5 PF12695.2 EGD94307.1 - 0.0012 18.6 0.1 0.0047 16.6 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EGD94307.1 - 0.0055 16.3 0.0 0.015 14.9 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 EGD94307.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.6 EGD94307.1 - 0.2 10.7 0.1 0.37 9.8 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Fcf1 PF04900.7 EGD94308.1 - 1.5e-39 134.1 2.7 1.7e-39 134.0 0.2 1.9 2 0 0 2 2 2 1 Fcf1 Ras PF00071.17 EGD94310.1 - 1.7e-32 112.0 0.0 2.1e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EGD94310.1 - 5.4e-05 22.5 0.0 6.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EGD94310.1 - 0.00011 22.6 0.0 0.00033 21.1 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EGD94310.1 - 0.017 14.5 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGD94310.1 - 0.022 14.0 0.4 0.032 13.5 0.0 1.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Ser_hydrolase PF06821.8 EGD94310.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase NCA2 PF08637.5 EGD94311.1 - 4.3e-80 268.7 0.1 2.3e-79 266.3 0.0 1.9 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Ribosomal_60s PF00428.14 EGD94311.1 - 0.0039 17.5 1.5 0.0076 16.6 1.0 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein Myc_N PF01056.13 EGD94311.1 - 0.094 11.8 0.4 0.15 11.1 0.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PBP_sp32 PF07222.7 EGD94311.1 - 0.14 11.2 1.5 0.26 10.4 1.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 FA_hydroxylase PF04116.8 EGD94312.1 - 5.6e-16 58.9 18.0 5.6e-16 58.9 12.5 1.8 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily AAA PF00004.24 EGD94313.1 - 8.5e-58 194.2 0.0 1.4e-40 138.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGD94313.1 - 8.6e-09 35.6 0.5 0.0011 18.9 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EGD94313.1 - 2.5e-06 27.6 1.7 0.085 12.9 0.0 3.7 3 1 1 4 4 3 2 AAA domain AAA_5 PF07728.9 EGD94313.1 - 9.3e-06 25.4 0.5 0.0038 16.9 0.1 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.13 EGD94313.1 - 1.8e-05 24.5 0.0 0.0041 16.7 0.0 3.1 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_28 PF13521.1 EGD94313.1 - 3.5e-05 23.8 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EGD94313.1 - 6.4e-05 22.8 0.0 0.068 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGD94313.1 - 0.00012 22.2 0.0 0.2 11.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.8 EGD94313.1 - 0.00012 20.9 0.3 0.0017 17.1 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 EGD94313.1 - 0.00017 21.0 2.1 3.4 7.0 0.1 3.8 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 EGD94313.1 - 0.00037 21.2 2.1 0.15 12.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_2 PF07724.9 EGD94313.1 - 0.00042 20.2 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EGD94313.1 - 0.00047 19.2 0.0 0.035 13.1 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EGD94313.1 - 0.0015 17.7 1.7 0.0088 15.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI CDC48_N PF02359.13 EGD94313.1 - 0.0016 18.3 0.0 0.048 13.5 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain DUF815 PF05673.8 EGD94313.1 - 0.0016 17.3 0.0 1.2 7.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Rad17 PF03215.10 EGD94313.1 - 0.0019 16.9 0.0 0.007 15.0 0.0 1.9 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EGD94313.1 - 0.0054 16.4 0.4 2.7 7.6 0.1 3.2 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 EGD94313.1 - 0.0055 16.1 0.0 0.75 9.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.7 EGD94313.1 - 0.008 15.8 0.6 4.8 6.8 0.1 3.1 3 1 0 3 3 3 1 NACHT domain AAA_30 PF13604.1 EGD94313.1 - 0.035 13.6 0.4 3 7.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.20 EGD94313.1 - 0.044 13.2 0.1 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activ_2 PF14532.1 EGD94313.1 - 0.059 13.4 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain MCM PF00493.18 EGD94313.1 - 0.086 11.6 0.1 12 4.6 0.0 2.4 2 0 0 2 2 2 0 MCM2/3/5 family AAA_24 PF13479.1 EGD94313.1 - 0.12 11.9 2.7 4.3 6.8 0.4 2.5 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EGD94313.1 - 0.14 11.8 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HNH_2 PF13391.1 EGD94314.1 - 5.8e-12 45.2 0.0 1.3e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease RRM_1 PF00076.17 EGD94315.1 - 1.6e-14 53.3 0.0 2.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD94315.1 - 1.1e-10 41.3 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD94315.1 - 7e-08 32.1 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EGD94315.1 - 0.0072 14.8 9.2 0.011 14.2 6.4 1.3 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 PI3_PI4_kinase PF00454.22 EGD94316.1 - 1.5e-48 165.2 0.1 3.6e-48 164.0 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EGD94316.1 - 4.7e-38 131.0 0.1 4.3e-37 127.9 0.0 2.2 2 0 0 2 2 2 1 FAT domain UME PF08064.8 EGD94316.1 - 1.8e-33 114.6 0.9 8.3e-33 112.5 0.1 2.8 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.15 EGD94316.1 - 2.3e-14 52.5 0.0 4.9e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 FATC domain TPR_14 PF13428.1 EGD94316.1 - 0.023 15.2 0.2 30 5.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Rad10 PF03834.9 EGD94316.1 - 0.027 14.1 0.1 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) TPR_19 PF14559.1 EGD94316.1 - 0.31 11.4 1.4 20 5.6 0.0 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat dCMP_cyt_deam_1 PF00383.17 EGD94317.1 - 2e-26 91.5 0.1 2.6e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EGD94317.1 - 0.0077 16.0 0.2 0.022 14.5 0.2 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase NADH_u_ox_C PF12853.2 EGD94318.1 - 1.5e-34 117.5 0.1 2.3e-34 116.9 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 EGD94318.1 - 7.4e-34 115.8 0.2 1.3e-33 115.0 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Swi3 PF07962.7 EGD94319.1 - 3e-29 100.4 0.1 6.1e-29 99.4 0.0 1.6 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 RCC1 PF00415.13 EGD94320.1 - 3.9e-61 203.0 14.4 8e-12 45.1 0.0 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGD94320.1 - 1.3e-40 136.1 38.4 9.5e-08 31.4 0.9 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RibD_C PF01872.12 EGD94321.1 - 6.1e-29 101.0 0.0 1.1e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 RibD C-terminal domain Nic96 PF04097.9 EGD94322.1 - 1.5e-211 703.7 0.0 1.9e-211 703.4 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 EGD94322.1 - 0.0069 16.6 24.8 0.0069 16.6 17.2 2.4 2 0 0 2 2 2 1 Nucleoporin FG repeat region COX16 PF14138.1 EGD94323.1 - 1.7e-31 108.1 0.1 2.4e-31 107.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Y_phosphatase PF00102.22 EGD94324.1 - 4.7e-66 222.4 0.0 7.1e-66 221.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EGD94324.1 - 3.3e-10 40.2 0.0 1.7e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 EGD94324.1 - 0.061 12.9 2.4 0.15 11.6 1.6 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EGD94324.1 - 0.19 11.9 0.2 0.57 10.4 0.1 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family F-box-like_2 PF13013.1 EGD94325.1 - 9.1e-07 28.5 0.5 3.2e-06 26.8 0.4 1.8 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.28 EGD94325.1 - 0.0018 17.8 2.2 0.0037 16.8 1.5 1.6 1 0 0 1 1 1 1 F-box domain RNA_pol_3_Rpc31 PF11705.3 EGD94325.1 - 0.8 9.6 14.7 1.3 8.9 10.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FGGY_C PF02782.11 EGD94327.1 - 1e-50 172.1 0.2 1.8e-50 171.3 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGD94327.1 - 4.6e-24 85.0 0.0 1.4e-21 76.9 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain AAA PF00004.24 EGD94330.1 - 1.1e-43 148.5 0.0 1.8e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGD94330.1 - 4.3e-08 32.9 0.0 1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGD94330.1 - 8e-08 32.3 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGD94330.1 - 3.7e-06 27.0 0.1 8.3e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGD94330.1 - 4.9e-06 26.7 0.1 0.00026 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD94330.1 - 7.3e-05 23.5 0.0 0.00016 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGD94330.1 - 7.9e-05 21.8 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGD94330.1 - 0.00014 21.5 0.1 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGD94330.1 - 0.00042 19.7 0.0 0.00079 18.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EGD94330.1 - 0.00088 18.0 0.0 0.0017 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EGD94330.1 - 0.0015 18.4 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGD94330.1 - 0.0017 18.2 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD94330.1 - 0.0025 16.9 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EGD94330.1 - 0.0026 17.3 0.0 0.0077 15.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGD94330.1 - 0.004 17.1 0.0 0.007 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGD94330.1 - 0.0069 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EGD94330.1 - 0.0077 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.1 EGD94330.1 - 0.0094 16.2 0.0 0.03 14.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 EGD94330.1 - 0.019 14.4 0.0 0.089 12.2 0.0 2.0 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.8 EGD94330.1 - 0.019 13.8 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EGD94330.1 - 0.021 14.2 0.1 0.082 12.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EGD94330.1 - 0.023 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGD94330.1 - 0.023 13.9 0.0 0.072 12.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 EGD94330.1 - 0.031 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EGD94330.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EGD94330.1 - 0.054 12.3 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EGD94330.1 - 0.08 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 EGD94330.1 - 0.092 12.8 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NACHT PF05729.7 EGD94330.1 - 0.11 12.2 0.0 0.56 9.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Na_Ca_ex PF01699.19 EGD94331.1 - 1.7e-30 105.4 24.6 5e-18 65.0 6.9 4.3 6 0 0 6 6 6 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EGD94331.1 - 3.9e-14 52.8 11.3 3.9e-14 52.8 7.9 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF307) Peptidase_S10 PF00450.17 EGD94332.1 - 1e-88 298.3 0.0 1.5e-88 297.7 0.0 1.2 1 1 0 1 1 1 1 Serine carboxypeptidase Choline_transpo PF04515.7 EGD94333.1 - 1.9e-102 342.4 19.9 1.9e-102 342.4 13.8 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter tRNA-synt_1g PF09334.6 EGD94334.1 - 1.8e-132 441.7 0.0 2.5e-132 441.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGD94334.1 - 6e-05 21.2 0.3 0.0028 15.7 0.0 3.1 2 2 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) HNH_2 PF13391.1 EGD94336.1 - 6.5e-15 54.6 0.0 1.6e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Alk_phosphatase PF00245.15 EGD94336.1 - 0.1 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Alkaline phosphatase Glyoxalase_2 PF12681.2 EGD94337.1 - 1.1e-08 35.6 0.0 1.3e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGD94337.1 - 0.047 13.6 0.0 0.35 10.8 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EMG1 PF03587.9 EGD94338.1 - 1e-77 260.0 0.0 1.2e-77 259.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase UPF0506 PF11703.3 EGD94339.1 - 0.0038 17.1 3.7 0.0056 16.6 2.5 1.2 1 0 0 1 1 1 1 UPF0506 Colipase-like PF15083.1 EGD94339.1 - 0.013 15.4 2.4 0.017 15.0 1.6 1.1 1 0 0 1 1 1 0 Colipase-like Toxin_29 PF08116.6 EGD94339.1 - 0.15 11.8 2.8 0.24 11.2 1.9 1.3 1 0 0 1 1 1 0 PhTx neurotoxin family DEC-1_N PF04625.8 EGD94339.1 - 0.16 10.6 7.4 0.3 9.7 5.2 1.4 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Toxin_18 PF08087.6 EGD94339.1 - 0.22 11.3 5.0 0.46 10.3 3.5 1.5 1 0 0 1 1 1 0 Conotoxin O-superfamily XPG_I PF00867.13 EGD94340.1 - 7.3e-29 99.6 0.4 2e-28 98.2 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EGD94340.1 - 5.8e-20 71.4 1.4 5.3e-17 61.9 0.0 2.9 2 1 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EGD94340.1 - 3.1e-05 24.1 0.4 0.00018 21.6 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF2229 PF09989.4 EGD94340.1 - 0.092 12.1 2.2 1.4 8.3 0.4 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) HXXSHH PF07586.6 EGD94340.1 - 0.17 10.7 3.3 0.35 9.7 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF4355 PF14265.1 EGD94340.1 - 5.7 6.8 21.5 1.6 8.6 10.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Linker_histone PF00538.14 EGD94341.1 - 2.7e-24 85.0 0.3 7.1e-24 83.7 0.2 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF650 PF04894.7 EGD94341.1 - 0.68 9.3 5.3 0.11 12.0 0.3 1.8 1 1 0 2 2 2 0 Archaeal protein of unknown function (DUF650) Pkinase PF00069.20 EGD94343.1 - 2.1e-11 43.4 0.0 3.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94343.1 - 0.00075 18.6 0.5 0.0064 15.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Oxidored_q4 PF00507.14 EGD94344.1 - 6.6e-15 54.7 2.7 6.6e-15 54.7 1.9 1.5 1 1 1 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Presenilin PF01080.12 EGD94344.1 - 0.06 12.1 0.1 0.061 12.1 0.1 1.0 1 0 0 1 1 1 0 Presenilin Ferric_reduct PF01794.14 EGD94344.1 - 0.075 13.1 0.1 0.093 12.8 0.1 1.1 1 0 0 1 1 1 0 Ferric reductase like transmembrane component zf-DHHC PF01529.15 EGD94344.1 - 6.9 6.0 6.1 7.5 5.9 4.3 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Pkinase PF00069.20 EGD94345.1 - 3.5e-21 75.5 0.0 3.4e-20 72.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94345.1 - 2.8e-07 29.8 0.0 1.1e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD94345.1 - 0.00023 20.2 0.0 0.09 11.7 0.0 2.5 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 EGD94345.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGD94345.1 - 0.037 13.0 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PhnH PF05845.7 EGD94345.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) PIP5K PF01504.13 EGD94346.1 - 9.2e-87 290.3 0.1 1.8e-86 289.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Apc1 PF12859.2 EGD94348.1 - 1.4e-28 99.1 0.3 5e-28 97.4 0.2 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EGD94348.1 - 2.8e-07 30.4 9.0 0.0058 16.8 0.1 4.8 5 0 0 5 5 5 3 Proteasome/cyclosome repeat Fungal_trans_2 PF11951.3 EGD94349.1 - 8.4e-61 205.6 0.2 1.4e-60 204.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EGD94350.1 - 5.6e-26 91.0 26.8 5.6e-26 91.0 18.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2053 PF09767.4 EGD94350.1 - 0.033 14.1 0.3 0.096 12.6 0.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2053) P5-ATPase PF12409.3 EGD94350.1 - 0.22 11.3 2.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 P5-type ATPase cation transporter RPAP1_C PF08620.5 EGD94354.1 - 7.2e-28 96.2 0.0 1.3e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EGD94354.1 - 9.5e-13 47.5 7.4 9.5e-13 47.5 5.1 1.9 1 1 1 2 2 2 1 RPAP1-like, N-terminal ABC2_membrane PF01061.19 EGD94355.1 - 1.5e-79 266.0 61.3 1.7e-41 141.7 15.8 3.2 4 1 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EGD94355.1 - 8.1e-40 136.2 0.0 1.5e-18 67.4 0.0 3.2 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.7 EGD94355.1 - 9.3e-34 115.1 9.2 9.1e-28 95.9 0.0 3.4 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EGD94355.1 - 1.7e-18 66.4 0.0 3.9e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EGD94355.1 - 9.2e-09 34.9 0.0 3.4e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EGD94355.1 - 3.7e-08 33.3 0.2 0.0013 18.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGD94355.1 - 2.2e-06 27.0 0.3 0.0015 17.9 0.1 2.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 EGD94355.1 - 5.8e-06 25.5 17.8 5.8e-06 25.5 12.3 3.6 3 1 1 4 4 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EGD94355.1 - 1.5e-05 24.2 0.1 0.00042 19.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EGD94355.1 - 1.7e-05 24.1 0.0 0.11 11.6 0.0 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGD94355.1 - 8.1e-05 23.4 0.0 0.033 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD94355.1 - 8.6e-05 22.5 0.2 0.0024 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EGD94355.1 - 0.00012 21.6 0.5 0.0011 18.3 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 EGD94355.1 - 0.00038 20.5 0.0 0.27 11.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EGD94355.1 - 0.00047 20.4 0.1 0.018 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGD94355.1 - 0.0013 18.9 0.2 0.16 12.0 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EGD94355.1 - 0.0014 18.9 0.0 0.14 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGD94355.1 - 0.0025 17.5 0.1 2.2 8.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 EGD94355.1 - 0.0049 16.8 0.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase PDR_assoc PF08370.6 EGD94355.1 - 0.0059 16.0 0.8 2.1 7.9 0.0 3.2 2 0 0 2 2 2 1 Plant PDR ABC transporter associated NACHT PF05729.7 EGD94355.1 - 0.0083 15.7 1.8 0.99 9.0 0.2 2.6 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 EGD94355.1 - 0.0099 16.3 0.0 4 7.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 EGD94355.1 - 0.018 15.2 0.1 3.6 7.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EGD94355.1 - 0.025 14.2 0.5 1.2 8.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EGD94355.1 - 0.049 13.8 0.0 21 5.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EGD94355.1 - 0.079 12.9 0.3 0.21 11.5 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGD94355.1 - 0.082 12.3 2.0 11 5.3 0.0 3.3 4 0 0 4 4 3 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EGD94355.1 - 0.09 12.2 0.1 4.6 6.6 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EGD94355.1 - 0.15 11.6 0.1 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EGD94355.1 - 0.29 10.0 0.0 5.9 5.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 EGD94355.1 - 0.42 9.3 0.2 6.7 5.4 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_15 PF13175.1 EGD94355.1 - 1 8.3 0.0 2.5 7.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain IDO PF01231.13 EGD94357.1 - 5.2e-06 25.1 1.1 4.9e-05 21.9 0.8 2.1 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase FAD_binding_3 PF01494.14 EGD94358.1 - 1.7e-12 47.0 0.5 1.1e-08 34.4 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGD94358.1 - 1.7e-06 27.2 0.1 0.00018 20.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD94358.1 - 9e-06 25.6 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGD94358.1 - 0.00026 19.7 0.0 0.032 12.8 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.1 EGD94358.1 - 0.00079 19.2 0.0 0.0089 15.8 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 EGD94358.1 - 0.0013 17.6 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 EGD94358.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.1 EGD94360.1 - 1.3e-18 67.2 0.1 2.5e-18 66.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD94360.1 - 2.2e-08 34.6 0.0 4.2e-07 30.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD94360.1 - 4.9e-07 30.1 0.0 1.2e-06 28.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD94360.1 - 5.2e-07 29.3 0.0 6.5e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD94360.1 - 8e-07 29.4 0.0 2e-05 24.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD94360.1 - 0.01 15.8 0.0 0.72 9.8 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EGD94360.1 - 0.011 14.8 0.0 0.61 9.0 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.14 EGD94360.1 - 0.042 13.8 0.0 0.097 12.6 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 EGD94360.1 - 0.12 11.7 0.0 0.89 8.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain IFRD PF05004.8 EGD94362.1 - 4.7e-30 104.7 6.0 6e-30 104.3 4.2 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 EGD94362.1 - 0.025 14.8 0.8 8.3 6.7 0.1 2.6 1 1 1 2 2 2 0 HEAT repeats ORC6 PF05460.8 EGD94362.1 - 0.55 9.2 9.0 0.047 12.7 2.3 1.9 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Corona_nucleoca PF00937.13 EGD94362.1 - 0.97 8.3 9.2 1.6 7.5 6.4 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Rep_4 PF05797.6 EGD94362.1 - 1.8 7.1 8.1 1.1 7.8 0.6 2.2 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) Pkinase PF00069.20 EGD94363.1 - 9.4e-60 201.9 0.0 1.2e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94363.1 - 5.1e-35 120.7 0.0 7e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD94363.1 - 0.0011 17.9 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGD94363.1 - 0.081 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EGD94363.1 - 0.12 12.1 0.0 0.4 10.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family SH2_2 PF14633.1 EGD94364.1 - 2.5e-85 285.0 0.0 2.5e-85 285.0 0.0 3.0 3 0 0 3 3 3 1 SH2 domain DLD PF14878.1 EGD94364.1 - 1.8e-35 121.5 5.3 1.8e-35 121.5 3.7 3.5 2 0 0 2 2 2 1 Death-like domain of SPT6 HHH_7 PF14635.1 EGD94364.1 - 1.1e-30 105.7 0.0 2.4e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EGD94364.1 - 1.3e-29 102.6 0.0 3.8e-29 101.1 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.1 EGD94364.1 - 1.2e-18 67.2 4.0 2.9e-17 62.7 2.7 2.8 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 EGD94364.1 - 2.2e-11 43.7 27.1 2.2e-11 43.7 18.8 4.2 5 1 0 5 5 5 1 Acidic N-terminal SPT6 HHH_3 PF12836.2 EGD94364.1 - 0.0001 22.1 0.0 0.00042 20.1 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif SH2 PF00017.19 EGD94364.1 - 0.00054 19.7 0.0 0.0015 18.3 0.0 1.8 1 0 0 1 1 1 1 SH2 domain DUF2716 PF10898.3 EGD94364.1 - 0.06 13.3 0.1 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) Acetyltransf_3 PF13302.1 EGD94365.1 - 7e-26 91.0 0.0 1.2e-25 90.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD94365.1 - 0.00027 20.9 0.0 0.0043 17.0 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGD94365.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein TBPIP PF07106.8 EGD94367.1 - 1.5e-32 112.5 7.2 1.8e-32 112.2 5.0 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 EGD94367.1 - 0.00078 19.8 4.0 0.0027 18.1 0.7 2.4 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) PspA_IM30 PF04012.7 EGD94367.1 - 0.0016 17.8 7.5 0.0016 17.8 5.2 1.9 1 1 1 2 2 2 1 PspA/IM30 family Penicillinase_R PF03965.11 EGD94367.1 - 0.0034 17.4 2.8 0.0041 17.2 1.2 1.7 1 1 0 2 2 2 1 Penicillinase repressor HutP PF09021.6 EGD94367.1 - 0.0071 16.5 0.7 0.015 15.5 0.2 1.7 1 1 1 2 2 2 1 HutP Transposase_22 PF02994.9 EGD94367.1 - 0.0095 14.4 5.1 0.01 14.3 3.6 1.1 1 0 0 1 1 1 1 L1 transposable element GreA_GreB_N PF03449.10 EGD94367.1 - 0.015 15.3 0.4 3.6 7.6 0.0 3.8 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal IncA PF04156.9 EGD94367.1 - 0.017 14.6 6.1 0.021 14.3 4.2 1.2 1 0 0 1 1 1 0 IncA protein Flexi_CP PF00286.15 EGD94367.1 - 0.037 13.7 0.8 0.31 10.7 0.1 2.3 1 1 1 2 2 2 0 Viral coat protein Viral_P18 PF04521.8 EGD94367.1 - 0.06 12.7 4.6 0.49 9.8 0.8 2.7 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein HTH_12 PF08461.5 EGD94367.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF3573 PF12097.3 EGD94367.1 - 0.18 10.4 1.6 0.21 10.1 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF1319 PF07028.6 EGD94367.1 - 0.19 11.9 7.4 2.9 8.1 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) FlxA PF14282.1 EGD94367.1 - 0.35 10.8 8.6 0.022 14.7 2.3 1.7 2 0 0 2 2 2 0 FlxA-like protein DUF3373 PF11853.3 EGD94367.1 - 0.37 9.2 3.9 0.54 8.7 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) TMF_DNA_bd PF12329.3 EGD94367.1 - 0.76 9.6 9.1 0.67 9.7 3.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIVA PF05103.8 EGD94367.1 - 0.77 9.8 6.0 0.85 9.6 0.8 2.4 1 1 1 2 2 2 0 DivIVA protein Ax_dynein_light PF10211.4 EGD94367.1 - 1.2 8.9 10.0 1.9 8.2 0.4 2.5 1 1 2 3 3 3 0 Axonemal dynein light chain DUF972 PF06156.8 EGD94367.1 - 1.2 9.4 5.1 11 6.4 3.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Sel1 PF08238.7 EGD94368.1 - 4.8e-12 46.0 4.2 3.1e-08 33.9 0.1 3.7 3 0 0 3 3 3 2 Sel1 repeat Mt_ATP-synt_B PF05405.9 EGD94368.1 - 0.14 11.6 0.4 0.21 11.0 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Helicase_C_2 PF13307.1 EGD94369.1 - 4.4e-54 182.9 0.0 2.1e-53 180.6 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EGD94369.1 - 1.9e-42 144.6 0.4 6.6e-42 142.8 0.2 1.9 1 1 0 1 1 1 1 DEAD_2 DEAD PF00270.24 EGD94369.1 - 0.072 12.5 0.0 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 EGD94369.1 - 0.12 12.5 0.1 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ribosomal_L18e PF00828.14 EGD94370.1 - 5.4e-36 123.8 0.0 7.1e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Abhydrolase_6 PF12697.2 EGD94371.1 - 9e-08 32.2 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD94371.1 - 1.8e-06 27.7 0.0 2.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGD94371.1 - 0.013 14.7 0.0 2.6 7.2 0.0 2.2 1 1 1 2 2 2 0 Prolyl oligopeptidase family PLDc PF00614.17 EGD94372.1 - 3e-17 61.7 1.0 2.3e-08 33.5 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EGD94372.1 - 2.8e-12 46.4 0.0 2e-07 30.7 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EGD94372.1 - 3.9e-10 39.5 1.1 8.6e-10 38.4 0.2 2.1 2 0 0 2 2 2 1 PX domain AA_permease PF00324.16 EGD94373.1 - 2.7e-46 157.9 18.0 4.3e-32 111.0 6.1 2.8 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EGD94373.1 - 2e-20 72.7 16.6 1.5e-17 63.2 2.9 2.5 2 1 1 3 3 3 2 Amino acid permease MtN3_slv PF03083.11 EGD94373.1 - 5.1 7.0 8.5 1.6 8.6 0.1 3.6 4 0 0 4 4 4 0 Sugar efflux transporter for intercellular exchange PH_7 PF15408.1 EGD94375.1 - 0.044 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Methyltransf_31 PF13847.1 EGD94376.1 - 6.2e-30 103.7 0.1 9.7e-30 103.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD94376.1 - 1.6e-16 60.5 0.2 8.1e-16 58.2 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD94376.1 - 9.7e-16 57.5 0.2 2.2e-15 56.4 0.1 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGD94376.1 - 2.2e-13 50.7 0.1 5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD94376.1 - 2.8e-13 50.0 0.1 8.8e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD94376.1 - 8.6e-11 41.8 0.0 1.6e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGD94376.1 - 2.4e-09 37.0 0.0 5e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EGD94376.1 - 4.8e-09 36.2 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD94376.1 - 1e-07 32.3 0.0 1.7e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGD94376.1 - 3.6e-07 29.6 0.4 6.1e-07 28.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGD94376.1 - 1.8e-06 27.4 0.1 3.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EGD94376.1 - 8e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGD94376.1 - 0.00011 21.3 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 EGD94376.1 - 0.0011 18.6 0.1 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.12 EGD94376.1 - 0.0012 17.9 0.1 0.0047 16.0 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase DOT1 PF08123.8 EGD94376.1 - 0.0016 17.7 1.4 0.003 16.8 0.4 1.9 2 1 0 2 2 2 1 Histone methylation protein DOT1 ADH_zinc_N PF00107.21 EGD94376.1 - 0.0056 16.2 0.1 0.16 11.5 0.0 2.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_15 PF09445.5 EGD94376.1 - 0.03 13.8 0.1 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.12 EGD94376.1 - 0.039 12.9 0.1 0.082 11.9 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase CmcI PF04989.7 EGD94376.1 - 0.086 12.1 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase GCD14 PF08704.5 EGD94376.1 - 0.14 11.6 0.0 1.8 7.9 0.0 2.0 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit bZIP_1 PF00170.16 EGD94377.1 - 0.04 13.8 6.9 0.056 13.3 4.5 1.5 1 1 0 1 1 1 0 bZIP transcription factor CCDC32 PF14989.1 EGD94377.1 - 0.098 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing 32 bZIP_2 PF07716.10 EGD94377.1 - 0.52 10.1 7.3 1.3 8.9 5.1 1.7 1 1 0 1 1 1 0 Basic region leucine zipper Peptidase_S41 PF03572.13 EGD94378.1 - 4.6e-09 35.9 0.0 1e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 VWA_2 PF13519.1 EGD94378.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Ras PF00071.17 EGD94379.1 - 2.7e-37 127.6 0.0 6.3e-24 84.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EGD94379.1 - 1.8e-10 41.3 0.0 3.8e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGD94379.1 - 0.0034 17.3 0.0 0.0062 16.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD94379.1 - 0.012 15.0 0.0 0.86 9.0 0.0 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.16 EGD94379.1 - 0.013 14.7 0.0 0.05 12.8 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family PRK PF00485.13 EGD94379.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zn_clus PF00172.13 EGD94380.1 - 6.1e-09 35.6 10.7 8.8e-09 35.1 7.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pacs-1 PF10254.4 EGD94380.1 - 0.9 8.1 3.6 1.7 7.2 2.5 1.5 1 1 0 1 1 1 0 PACS-1 cytosolic sorting protein Aldose_epim PF01263.15 EGD94381.1 - 2.3e-58 197.6 0.0 2.8e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Glyoxalase_2 PF12681.2 EGD94382.1 - 1.5e-11 44.8 0.0 1.7e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGD94382.1 - 0.0062 16.5 0.0 0.012 15.5 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SseB_C PF14581.1 EGD94382.1 - 0.15 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 SseB protein C-terminal domain QRPTase_C PF01729.14 EGD94383.1 - 5.7e-48 162.6 0.4 4.1e-25 88.2 0.0 2.1 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EGD94383.1 - 3.5e-25 87.6 0.0 8.9e-25 86.3 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain SWI-SNF_Ssr4 PF08549.5 EGD94383.1 - 0.017 13.4 0.4 0.021 13.1 0.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Mto2_bdg PF12808.2 EGD94384.1 - 3.9e-29 100.5 32.0 3.6e-19 68.5 14.0 9.8 10 2 1 11 11 11 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Microtub_assoc PF07989.6 EGD94384.1 - 6.4e-22 77.1 9.3 6.4e-22 77.1 6.4 7.2 7 1 1 8 8 8 1 Microtubule associated Reo_sigmaC PF04582.7 EGD94384.1 - 0.0013 17.9 2.6 0.0013 17.9 1.8 5.2 3 1 3 6 6 6 3 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EGD94384.1 - 0.0035 17.4 6.7 0.0035 17.4 4.6 7.9 3 1 6 10 10 10 4 Fibrinogen alpha/beta chain family Sec7 PF01369.15 EGD94385.1 - 2.4e-41 141.5 0.0 5.3e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EGD94385.1 - 7e-20 71.3 0.0 1.6e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Lzipper-MIP1 PF14389.1 EGD94385.1 - 0.036 14.1 0.3 0.096 12.8 0.2 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 COesterase PF00135.23 EGD94387.1 - 2.2e-34 119.0 0.0 2.9e-22 79.1 0.0 2.9 1 1 2 3 3 3 3 Carboxylesterase family UNC-50 PF05216.8 EGD94388.1 - 2.9e-70 236.0 1.7 4.7e-70 235.3 1.2 1.3 1 1 0 1 1 1 1 UNC-50 family FAD_binding_3 PF01494.14 EGD94390.1 - 1.7e-16 60.2 0.0 2.9e-06 26.5 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox PF00070.22 EGD94390.1 - 1.6e-07 31.5 0.0 0.00011 22.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD94390.1 - 3.4e-07 30.1 0.1 7.5e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD94390.1 - 2.4e-05 23.4 0.0 3.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD94390.1 - 0.0045 15.8 0.0 0.007 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGD94390.1 - 0.0056 16.5 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EGD94390.1 - 0.024 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.7 EGD94390.1 - 0.039 12.8 0.1 0.26 10.1 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EGD94390.1 - 0.044 13.4 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PQQ PF01011.16 EGD94390.1 - 0.047 13.2 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 PQQ enzyme repeat Shikimate_DH PF01488.15 EGD94390.1 - 0.078 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EGD94390.1 - 0.11 11.0 0.0 0.35 9.2 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 EGD94390.1 - 0.14 12.1 0.0 0.51 10.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EGD94390.1 - 0.18 11.2 0.1 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 EGD94392.1 - 2.7e-34 118.4 28.6 4.4e-34 117.7 19.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1049 PF06305.6 EGD94392.1 - 2.2 7.7 0.0 2.2 7.7 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF1049) PP28 PF10252.4 EGD94393.1 - 4.5e-30 103.5 22.7 4.5e-30 103.5 15.8 3.7 2 2 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 Daxx PF03344.10 EGD94393.1 - 0.61 8.5 31.9 0.85 8.0 22.1 1.2 1 0 0 1 1 1 0 Daxx Family DUF2887 PF11103.3 EGD94393.1 - 0.64 9.5 4.4 1.1 8.7 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) MFS_1 PF07690.11 EGD94394.1 - 4e-18 65.2 49.7 4.9e-18 64.9 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 EGD94395.1 - 4.6e-17 61.8 0.0 6.7e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGD94395.1 - 3.7e-06 26.5 0.0 6.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGD94395.1 - 1.3e-05 25.2 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGD94395.1 - 4.4e-05 23.5 0.0 0.00011 22.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD94395.1 - 0.00033 20.4 0.0 0.00058 19.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EGD94395.1 - 0.007 16.2 0.0 0.0088 15.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGD94395.1 - 0.016 15.3 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGD94395.1 - 0.018 15.0 0.0 0.061 13.2 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EGD94395.1 - 0.049 13.2 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_20 PF00982.16 EGD94396.1 - 1.4e-148 495.3 0.0 2.3e-148 494.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EGD94396.1 - 8e-89 296.5 0.0 1.5e-88 295.6 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase HAD PF12710.2 EGD94396.1 - 0.032 14.3 0.0 0.22 11.6 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.1 EGD94396.1 - 0.13 12.4 0.0 1.1 9.4 0.0 2.4 2 1 1 3 3 3 0 Glycosyl transferases group 1 Glyco_hydro_44 PF12891.2 EGD94397.1 - 0.0094 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase family 44 NTP_transf_2 PF01909.18 EGD94397.1 - 0.021 15.1 0.0 0.058 13.7 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain LETM1 PF07766.8 EGD94398.1 - 9.7e-07 28.0 2.8 0.00028 19.9 0.3 2.8 1 1 2 3 3 3 2 LETM1-like protein ZZ PF00569.12 EGD94399.1 - 4e-17 61.4 36.0 4.6e-07 29.2 5.9 3.6 3 0 0 3 3 3 3 Zinc finger, ZZ type Btz PF09405.5 EGD94401.1 - 4.4e-23 81.7 6.6 4.4e-23 81.7 4.6 2.6 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.17 EGD94402.1 - 4.7e-23 80.6 0.3 3.3e-15 55.4 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD94402.1 - 6.4e-21 74.1 0.0 6.6e-13 48.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD94402.1 - 4.1e-06 26.5 0.1 0.00032 20.4 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD94402.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ino80_Iec3 PF14612.1 EGD94403.1 - 1.6e-82 277.0 8.1 2.3e-82 276.5 5.6 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling ASFV_J13L PF05568.6 EGD94403.1 - 7.9 5.9 7.6 22 4.5 0.4 2.6 2 0 0 2 2 2 0 African swine fever virus J13L protein FAD_binding_4 PF01565.18 EGD94404.1 - 1.3e-15 57.0 1.3 3.1e-15 55.8 0.9 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD94404.1 - 4e-11 42.6 0.3 1.7e-10 40.6 0.1 2.2 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 EGD94404.1 - 0.055 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding GFA PF04828.9 EGD94405.1 - 9.7e-20 70.3 0.7 1.3e-19 69.9 0.5 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EGD94405.1 - 0.8 9.5 5.1 3.1 7.6 3.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon Dynamin_N PF00350.18 EGD94406.1 - 2.8e-31 108.5 0.1 6.8e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGD94406.1 - 1.2e-11 44.0 0.2 1.1e-10 40.7 0.1 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EGD94406.1 - 7.8e-06 25.8 0.0 6e-05 22.9 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EGD94406.1 - 0.00079 19.9 0.1 0.0032 17.9 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein GED PF02212.13 EGD94406.1 - 0.018 14.9 1.5 0.3 11.0 0.1 2.8 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_29 PF13555.1 EGD94406.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EGD94406.1 - 0.079 12.2 0.1 6.8 5.9 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_23 PF13476.1 EGD94406.1 - 7.5 6.8 9.6 1.1 9.4 1.5 2.9 1 1 1 2 2 2 0 AAA domain ECR1_N PF14382.1 EGD94407.1 - 8.4e-09 34.5 0.0 1.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EGD94407.1 - 0.0019 18.1 0.1 0.032 14.1 0.1 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Oxysterol_BP PF01237.13 EGD94408.1 - 8.9e-119 396.0 0.2 1.6e-118 395.2 0.0 1.5 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EGD94408.1 - 1e-39 134.4 0.9 3.8e-39 132.6 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EGD94408.1 - 0.00047 20.3 0.9 0.00085 19.4 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EGD94408.1 - 0.22 11.7 9.8 0.055 13.7 2.5 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain Plus-3 PF03126.13 EGD94409.1 - 1.3e-28 99.1 0.0 6.5e-28 96.9 0.0 2.2 3 0 0 3 3 3 1 Plus-3 domain COQ7 PF03232.8 EGD94410.1 - 3.3e-61 205.7 0.1 4.3e-61 205.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EGD94410.1 - 0.007 16.6 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 Rubrerythrin DUF1817 PF08847.6 EGD94410.1 - 0.11 12.0 0.1 3 7.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1817) Phytoreo_Pns PF05451.6 EGD94410.1 - 0.13 10.8 0.1 0.19 10.3 0.1 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 SUZ PF12752.2 EGD94410.1 - 0.15 12.5 1.5 0.28 11.7 1.0 1.4 1 0 0 1 1 1 0 SUZ domain LMWPc PF01451.16 EGD94411.1 - 6.5e-34 117.2 0.0 7.5e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Chitin_synth_1 PF01644.12 EGD94412.1 - 1.6e-80 268.6 0.0 2.3e-80 268.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGD94412.1 - 3.5e-31 106.7 0.0 7.1e-31 105.7 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGD94412.1 - 6.4e-21 74.3 2.3 7.3e-17 60.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EGD94412.1 - 4.5e-08 33.1 0.0 2.1e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGD94412.1 - 7.6e-06 25.7 13.7 7.6e-06 25.7 9.5 3.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Lipase_GDSL_2 PF13472.1 EGD94413.1 - 6.1e-19 68.8 0.7 2e-18 67.1 0.5 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family UPF0546 PF10639.4 EGD94414.1 - 1.7e-36 124.4 2.9 2.5e-35 120.7 2.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EGD94414.1 - 0.0049 16.9 3.8 0.0049 16.9 2.6 2.0 2 1 0 2 2 2 1 EamA-like transporter family DUF1211 PF06736.6 EGD94414.1 - 0.074 13.2 0.9 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) EmrE PF13536.1 EGD94414.1 - 0.61 10.3 9.5 0.027 14.6 2.6 1.8 2 1 0 2 2 2 0 Multidrug resistance efflux transporter PAT1 PF09770.4 EGD94416.1 - 0.32 9.2 12.5 0.36 9.0 8.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PhyH PF05721.8 EGD94417.1 - 1.2e-42 146.2 0.0 1.5e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3298 PF11738.3 EGD94417.1 - 0.093 13.2 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3298) UTP15_C PF09384.5 EGD94418.1 - 4e-50 169.3 0.0 7e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EGD94418.1 - 2.8e-23 80.8 5.3 3.7e-07 29.7 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EGD94418.1 - 2.3e-05 23.9 0.4 0.00058 19.3 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 EGD94418.1 - 0.068 11.2 1.3 0.31 9.1 0.6 2.1 1 1 0 1 1 1 0 Nucleoporin Nup120/160 LRS4 PF10422.4 EGD94418.1 - 0.4 10.0 2.2 0.3 10.4 0.2 1.7 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 C2 PF00168.25 EGD94419.1 - 2.4e-12 46.5 0.0 4.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain AAA_12 PF13087.1 EGD94420.1 - 5.9e-25 87.8 0.0 1.6e-19 70.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.1 EGD94420.1 - 9e-11 41.8 0.1 0.00046 19.8 0.0 2.6 1 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGD94420.1 - 0.0004 20.0 0.0 0.0038 16.9 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EGD94420.1 - 0.0041 16.6 0.0 0.31 10.5 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EGD94420.1 - 0.0072 15.6 0.0 0.048 12.9 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EGD94420.1 - 0.12 11.8 0.0 10 5.4 0.0 2.6 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain DUF2457 PF10446.4 EGD94420.1 - 4.7 5.8 9.9 7 5.2 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Fungal_trans PF04082.13 EGD94421.1 - 7.7e-13 47.9 0.4 1.2e-12 47.3 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD94421.1 - 1.8e-10 40.5 10.5 3.7e-10 39.5 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBR PF01485.16 EGD94422.1 - 9.9e-05 22.1 6.4 9.9e-05 22.1 4.5 5.4 5 1 0 5 5 5 2 IBR domain OTU PF02338.14 EGD94423.1 - 8.9e-13 48.8 0.0 1.5e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.3 EGD94423.1 - 0.016 15.4 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 UBX PF00789.15 EGD94423.1 - 0.16 12.0 0.4 1.8 8.6 0.3 2.4 1 1 0 1 1 1 0 UBX domain Bromodomain PF00439.20 EGD94424.1 - 2.1e-36 123.6 3.6 1.5e-19 69.6 0.2 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EGD94424.1 - 6.7e-16 58.1 0.8 1.4e-15 57.1 0.6 1.6 1 0 0 1 1 1 1 BAH domain Atg14 PF10186.4 EGD94424.1 - 0.081 11.8 3.6 0.15 10.9 2.5 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Nucleoplasmin PF03066.10 EGD94424.1 - 0.55 9.7 9.0 1.2 8.6 6.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin Nucleo_P87 PF07267.6 EGD94424.1 - 0.99 8.0 11.1 0.24 10.0 0.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 MRC1 PF09444.5 EGD94425.1 - 3.1e-38 131.3 18.8 3.1e-38 131.3 13.0 5.2 3 1 1 4 4 4 2 MRC1-like domain Hydrolase_like PF13242.1 EGD94427.1 - 8e-05 22.2 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EGD94427.1 - 0.01 16.0 0.3 1.2 9.2 0.1 3.2 3 2 0 3 3 3 0 Haloacid dehalogenase-like hydrolase MIF4G PF02854.14 EGD94428.1 - 1e-23 83.8 4.3 4.1e-22 78.6 2.6 2.3 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.12 EGD94428.1 - 7.1e-17 61.1 0.4 2.4e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.10 EGD94429.1 - 6.1e-25 86.9 0.1 7.8e-25 86.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Inp1 PF12634.2 EGD94430.1 - 1.1e-32 112.6 0.0 2.5e-32 111.5 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 EGD94431.1 - 0.019 14.4 16.5 4.6 6.6 11.4 3.1 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF1136 PF06582.7 EGD94432.1 - 0.035 13.7 0.3 0.07 12.8 0.2 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1136) Sugar_tr PF00083.19 EGD94433.1 - 6.6e-42 143.6 23.6 2.8e-28 98.7 4.4 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EGD94433.1 - 3.2e-22 78.7 24.9 1.6e-21 76.4 13.9 2.8 1 1 0 2 2 2 2 Major Facilitator Superfamily NADHdeh_related PF10125.4 EGD94435.1 - 0.04 13.0 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein DUF2841 PF11001.3 EGD94437.1 - 1.7e-27 95.7 0.0 2.5e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF4237 PF14021.1 EGD94438.1 - 1.4e-30 105.3 0.0 2.1e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4237) FmdA_AmdA PF03069.10 EGD94439.1 - 4e-137 456.8 0.0 1e-136 455.4 0.0 1.5 1 1 0 1 1 1 1 Acetamidase/Formamidase family Pro_isomerase PF00160.16 EGD94440.1 - 1.7e-38 132.2 0.2 3.5e-38 131.2 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EGD94440.1 - 1.7e-08 34.0 8.6 0.00073 19.1 1.1 2.4 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EGD94440.1 - 8.6e-06 25.2 6.0 7.2e-05 22.4 0.8 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGD94440.1 - 4.8e-05 22.7 0.5 4.8e-05 22.7 0.4 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD94440.1 - 0.0034 18.0 10.8 0.065 13.9 5.9 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGD94440.1 - 0.0076 16.1 6.5 0.06 13.2 3.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGD94440.1 - 0.084 12.6 0.2 0.084 12.6 0.1 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGD94440.1 - 0.13 12.1 3.6 0.89 9.4 1.2 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGD94440.1 - 0.18 12.5 6.0 0.3 11.8 0.8 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.11 EGD94441.1 - 7.1e-46 155.7 0.1 8e-46 155.6 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF29 PF01724.11 EGD94441.1 - 0.083 12.7 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF29 Not3 PF04065.10 EGD94442.1 - 2e-96 321.8 15.3 3e-96 321.2 10.6 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EGD94442.1 - 1.6e-38 131.5 5.9 4.3e-38 130.2 4.1 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Poty_PP PF08440.5 EGD94442.1 - 0.0025 16.9 0.8 0.0056 15.7 0.6 1.5 1 0 0 1 1 1 1 Potyviridae polyprotein DUF2373 PF10180.4 EGD94442.1 - 0.02 14.4 3.8 0.045 13.3 2.6 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 EGD94442.1 - 0.077 12.9 0.3 0.077 12.9 0.2 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Snapin_Pallidin PF14712.1 EGD94442.1 - 3.5 7.9 8.5 4.9 7.5 0.7 2.4 2 0 0 2 2 2 0 Snapin/Pallidin zf-C2H2_4 PF13894.1 EGD94444.1 - 0.00017 21.6 8.1 0.11 12.9 0.5 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD94444.1 - 0.0068 16.6 8.5 0.17 12.2 0.1 3.1 2 1 0 2 2 2 2 Zinc finger, C2H2 type APH PF01636.18 EGD94445.1 - 1.7e-15 57.4 0.0 4.9e-15 55.9 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family DNA_binding_1 PF01035.15 EGD94447.1 - 2.3e-23 81.7 0.0 3.3e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Rubella_Capsid PF05750.6 EGD94447.1 - 0.0031 16.9 0.2 0.0057 16.1 0.0 1.5 2 0 0 2 2 2 1 Rubella capsid protein Sugar_tr PF00083.19 EGD94448.1 - 3.6e-84 282.9 21.2 4.2e-84 282.7 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD94448.1 - 4.7e-19 68.3 49.0 2.2e-14 52.9 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGD94448.1 - 0.021 12.8 1.4 0.032 12.3 0.0 1.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 EGD94448.1 - 0.18 11.8 9.4 1.7 8.7 1.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) Pyr_redox_dim PF02852.17 EGD94449.1 - 4.8e-39 132.7 0.1 1.4e-38 131.2 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EGD94449.1 - 3.8e-29 102.0 10.6 3.5e-28 98.8 7.8 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD94449.1 - 7.2e-22 77.5 13.5 9e-21 74.0 0.8 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD94449.1 - 4e-11 42.6 6.1 9.3e-11 41.4 0.1 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD94449.1 - 2.3e-09 37.1 5.0 5.5e-05 23.1 0.4 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EGD94449.1 - 1.4e-08 34.0 13.1 2.6e-07 29.8 3.5 3.0 2 2 1 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EGD94449.1 - 2e-07 30.2 11.6 3.3e-07 29.5 1.8 2.9 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.19 EGD94449.1 - 4.8e-07 28.9 11.6 0.00032 19.7 0.1 3.4 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGD94449.1 - 1e-06 28.9 0.3 3.6e-06 27.1 0.1 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD94449.1 - 3e-06 25.9 10.4 0.00038 19.0 1.0 3.2 3 0 0 3 3 3 3 HI0933-like protein Thi4 PF01946.12 EGD94449.1 - 5.6e-06 25.6 3.9 0.00012 21.2 0.1 2.3 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 EGD94449.1 - 1.4e-05 24.7 1.7 0.0096 15.5 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EGD94449.1 - 0.00036 19.5 0.2 0.012 14.5 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EGD94449.1 - 0.009 15.1 7.7 0.11 11.4 1.0 2.4 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.1 EGD94449.1 - 0.018 13.9 0.2 0.065 12.1 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EGD94449.1 - 0.13 10.4 0.9 0.29 9.2 0.1 1.8 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.1 EGD94449.1 - 0.57 10.4 4.8 2.1 8.6 0.1 3.0 3 1 0 3 3 3 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 EGD94449.1 - 1.3 7.5 7.3 0.86 8.1 0.6 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 EGD94449.1 - 3.4 7.2 9.9 0.15 11.6 0.5 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PGM_PMM_I PF02878.11 EGD94451.1 - 2.3e-33 114.5 0.0 5.5e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EGD94451.1 - 1.8e-24 86.0 0.0 4.5e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EGD94451.1 - 2.5e-14 53.2 0.0 4.6e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EGD94451.1 - 3.7e-08 33.2 0.0 9.2e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AdoMet_MTase PF07757.8 EGD94451.1 - 0.045 13.8 0.0 17 5.5 0.0 2.7 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase FA_desaturase PF00487.19 EGD94452.1 - 4e-34 118.2 31.3 6.7e-34 117.4 21.7 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGD94452.1 - 1.4e-12 47.2 0.0 3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CUE PF02845.11 EGD94453.1 - 1.2e-10 40.5 0.1 2.7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 CUE domain GldM_N PF12081.3 EGD94453.1 - 0.025 14.1 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 GldM N-terminal domain GTP_cyclohydro2 PF00925.15 EGD94453.1 - 0.091 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase II Ribosomal_S10 PF00338.17 EGD94454.1 - 2e-28 98.0 0.5 2.4e-28 97.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH PF00642.19 EGD94455.1 - 7.5e-06 25.5 2.7 1.5e-05 24.5 1.9 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGD94455.1 - 0.093 12.7 2.1 0.29 11.2 1.5 1.9 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type ELYS PF13934.1 EGD94456.1 - 6e-77 258.3 0.1 7.8e-77 258.0 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 EGD94457.1 - 2.5e-69 232.8 30.4 1.1e-68 230.7 21.1 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGD94457.1 - 1.7e-28 98.9 0.3 1.3e-27 96.1 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGD94457.1 - 4.4e-11 43.2 11.0 2.9e-05 24.1 0.4 3.1 2 2 0 2 2 2 2 AAA domain Reo_sigmaC PF04582.7 EGD94457.1 - 0.00034 19.9 1.0 0.00034 19.9 0.7 5.2 3 2 2 6 6 6 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 EGD94457.1 - 0.00037 19.9 0.0 0.00078 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Filament PF00038.16 EGD94457.1 - 0.00049 19.6 14.2 0.00049 19.6 9.8 5.2 2 2 4 6 6 6 1 Intermediate filament protein ATG16 PF08614.6 EGD94457.1 - 0.0037 17.0 17.8 0.0037 17.0 12.3 8.1 3 2 6 9 9 7 2 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 EGD94457.1 - 0.0038 17.3 9.9 0.0038 17.3 6.9 6.9 3 2 6 9 9 8 2 Fibrinogen alpha/beta chain family CRCB PF02537.10 EGD94457.1 - 0.26 11.1 0.0 0.49 10.3 0.0 1.3 1 0 0 1 1 1 0 CrcB-like protein IncA PF04156.9 EGD94457.1 - 7.6 6.0 121.7 0.014 14.9 13.9 8.1 3 2 5 8 8 8 0 IncA protein Stm1_N PF09598.5 EGD94457.1 - 8.7 7.1 14.7 1.6 9.4 5.0 3.5 2 0 0 2 2 2 0 Stm1 Fungal_trans PF04082.13 EGD94458.1 - 7.2e-11 41.4 0.2 1.7e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD94458.1 - 4e-08 33.0 4.8 7.7e-08 32.1 3.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.9 EGD94458.1 - 1.3 6.9 5.6 1.8 6.4 3.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Suc_Fer-like PF06999.7 EGD94459.1 - 9.9e-47 159.8 0.0 1.3e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Ribonuc_L-PSP PF01042.16 EGD94460.1 - 2.3e-10 40.2 0.1 3.6e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.27 EGD94461.1 - 2.8e-10 39.6 4.3 0.0011 18.7 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat RNA_pol_N PF01194.12 EGD94462.1 - 2.3e-30 104.4 1.7 2.6e-30 104.2 1.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EGD94462.1 - 0.052 13.6 0.9 0.1 12.7 0.6 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Fer4_13 PF13370.1 EGD94463.1 - 0.25 11.7 3.1 8.7 6.8 0.3 4.0 3 2 0 3 3 3 0 4Fe-4S single cluster domain PBP1_TM PF14812.1 EGD94463.1 - 4 7.8 7.1 16 5.8 0.6 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sugar_tr PF00083.19 EGD94464.1 - 2.3e-107 359.3 27.5 2.7e-107 359.1 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD94464.1 - 5.7e-24 84.4 39.9 2.9e-15 55.8 8.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.1 EGD94465.1 - 3.8e-33 114.4 0.0 3.5e-31 108.1 0.0 2.4 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGD94465.1 - 3.7e-14 52.8 0.0 8.4e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EGD94466.1 - 1.4e-36 125.9 52.1 2.4e-36 125.2 34.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2254 PF10011.4 EGD94466.1 - 0.0025 16.3 0.0 0.0052 15.3 0.0 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) Sarcolipin PF05366.6 EGD94466.1 - 0.052 12.9 0.1 0.13 11.7 0.1 1.7 1 0 0 1 1 1 0 Sarcolipin DNA_primase_S PF01896.14 EGD94467.1 - 7.1e-54 181.5 0.0 1.6e-53 180.4 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit CDC27 PF09507.5 EGD94467.1 - 2.5 7.2 24.6 0.051 12.7 12.4 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MAM33 PF02330.11 EGD94468.1 - 2.8e-33 115.4 0.8 3.4e-33 115.1 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3567 PF12091.3 EGD94468.1 - 0.14 12.1 0.6 0.9 9.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3567) cobW PF02492.14 EGD94469.1 - 1.2e-47 161.7 6.1 4.6e-36 123.9 0.8 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EGD94469.1 - 8.7e-22 76.6 0.0 1.6e-17 63.0 0.0 2.9 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain AAA_33 PF13671.1 EGD94469.1 - 0.0031 17.4 0.0 0.079 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EGD94469.1 - 0.011 15.3 1.1 0.039 13.6 0.0 2.4 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EGD94469.1 - 0.022 15.0 0.2 0.097 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGD94469.1 - 0.029 14.4 0.3 0.13 12.4 0.2 2.2 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 EGD94469.1 - 0.036 12.8 0.4 1.2 7.8 0.0 2.3 2 0 0 2 2 2 0 ArgK protein T2SE PF00437.15 EGD94469.1 - 0.04 12.7 0.0 0.08 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EGD94469.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EGD94469.1 - 0.063 12.8 0.1 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EGD94469.1 - 0.086 11.9 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.13 EGD94469.1 - 0.093 12.2 0.1 0.27 10.7 0.0 1.8 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EGD94469.1 - 0.11 12.5 0.1 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain UPF0079 PF02367.12 EGD94469.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF2962 PF11176.3 EGD94470.1 - 2.6e-46 157.0 4.3 2.9e-46 156.8 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF4510 PF14971.1 EGD94470.1 - 0.032 14.4 2.7 2.6 8.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) XPG_I PF00867.13 EGD94471.1 - 2.9e-24 84.9 0.0 5.8e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGD94471.1 - 1e-23 83.4 0.0 1.4e-22 79.8 0.0 2.5 3 0 0 3 3 3 1 XPG N-terminal domain XPG_I_2 PF12813.2 EGD94471.1 - 0.0069 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.12 EGD94471.1 - 0.13 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Fig1 PF12351.3 EGD94472.1 - 2.7e-57 193.6 4.6 2.7e-57 193.6 3.2 1.9 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EGD94472.1 - 7.6e-09 35.4 8.4 2.2e-08 33.9 5.8 1.7 1 1 0 1 1 1 1 SUR7/PalI family FmdA_AmdA PF03069.10 EGD94472.1 - 0.097 11.3 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Acetamidase/Formamidase family MLTD_N PF06474.7 EGD94472.1 - 0.21 11.8 7.4 0.1 12.7 2.6 2.4 2 0 0 2 2 2 0 MltD lipid attachment motif DUF898 PF05987.8 EGD94472.1 - 0.32 9.8 13.1 0.023 13.6 4.7 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 EGD94472.1 - 0.44 10.7 10.0 0.31 11.2 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF2410 PF10307.4 EGD94475.1 - 4.5e-84 280.7 0.0 7e-84 280.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) zf-RING_2 PF13639.1 EGD94476.1 - 3.2e-08 33.2 8.0 5.6e-08 32.4 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGD94476.1 - 6.9e-06 25.9 9.5 1.1e-05 25.2 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD94476.1 - 2.4e-05 23.9 7.8 3.9e-05 23.2 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD94476.1 - 9.4e-05 21.9 8.3 0.00017 21.1 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD94476.1 - 0.0062 16.6 9.9 0.022 14.8 6.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGD94476.1 - 0.34 10.6 5.2 0.63 9.8 3.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Drc1-Sld2 PF11719.3 EGD94477.1 - 8.6e-84 282.0 22.3 9.8e-84 281.9 15.4 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein 2-oxoacid_dh PF00198.18 EGD94478.1 - 1.4e-80 269.8 0.0 2.6e-80 269.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGD94478.1 - 2.4e-16 59.1 1.5 2.4e-16 59.1 1.1 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme GCV_H PF01597.14 EGD94478.1 - 0.094 12.3 0.4 0.21 11.2 0.3 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein FAP PF07174.6 EGD94478.1 - 0.26 10.5 13.1 0.41 9.9 9.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF4551 PF15087.1 EGD94478.1 - 0.59 8.4 5.6 1 7.6 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Neisseria_TspB PF05616.8 EGD94478.1 - 3.4 5.9 11.9 5 5.3 8.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein MSA-2c PF12238.3 EGD94478.1 - 9.9 5.7 9.4 6.3 6.3 5.1 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Complex1_LYR PF05347.10 EGD94479.1 - 0.0003 20.5 0.5 0.00048 19.8 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGD94479.1 - 0.0012 19.0 0.2 0.002 18.2 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Histone PF00125.19 EGD94480.1 - 3.7e-24 84.6 0.0 4.6e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGD94480.1 - 4.3e-05 23.4 0.0 5.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4336 PF14234.1 EGD94480.1 - 0.15 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Histone PF00125.19 EGD94481.1 - 7.4e-17 61.2 0.2 1.1e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGD94481.1 - 0.059 13.4 0.0 0.059 13.4 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_C54 PF03416.14 EGD94482.1 - 3.1e-96 321.7 0.0 7.5e-96 320.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase family C54 R3H PF01424.17 EGD94483.1 - 6.8e-11 41.7 0.0 1.6e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EGD94483.1 - 3.8e-09 36.1 0.3 8.7e-09 35.0 0.2 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGD94483.1 - 0.0033 17.2 0.2 0.0033 17.2 0.1 3.2 5 0 0 5 5 5 1 DExH-box splicing factor binding site DnaJ PF00226.26 EGD94484.1 - 1.6e-26 91.8 0.3 1.6e-26 91.8 0.2 2.1 2 0 0 2 2 2 1 DnaJ domain zf-met PF12874.2 EGD94484.1 - 1.3e-12 47.4 7.5 3.3e-09 36.6 1.7 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGD94484.1 - 7.5e-12 45.0 9.8 1.4e-09 37.7 3.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGD94484.1 - 5.4e-10 39.2 6.3 0.00025 21.1 1.3 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EGD94484.1 - 4.1e-07 29.9 6.6 0.0052 17.0 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD94484.1 - 1.2e-05 25.2 4.1 0.046 14.0 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGD94484.1 - 0.00024 20.8 8.2 0.024 14.5 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger LIM PF00412.17 EGD94484.1 - 0.0094 16.0 2.2 0.65 10.1 0.3 2.4 2 0 0 2 2 2 1 LIM domain zf-BED PF02892.10 EGD94484.1 - 0.027 14.2 0.2 3.7 7.3 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger DUF3449 PF11931.3 EGD94484.1 - 0.076 12.5 5.4 0.098 12.1 1.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) DUF2175 PF09943.4 EGD94484.1 - 0.08 13.0 1.9 0.99 9.4 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) zf-H2C2_2 PF13465.1 EGD94484.1 - 0.11 12.7 1.7 2.4 8.6 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain AKAP95 PF04988.7 EGD94484.1 - 0.75 9.5 9.1 0.31 10.8 1.8 2.5 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Choline_kin_N PF04428.9 EGD94485.1 - 0.041 13.3 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 Choline kinase N terminus ACC_epsilon PF13822.1 EGD94485.1 - 4.3 7.7 0.0 4.3 7.7 0.0 3.2 4 0 0 4 4 4 0 Acyl-CoA carboxylase epsilon subunit YccV-like PF08755.6 EGD94486.1 - 2.1e-26 91.7 0.1 5.9e-26 90.3 0.0 1.8 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EGD94486.1 - 1.3e-13 50.7 0.0 3.3e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EGD94486.1 - 8.7e-06 25.3 0.0 2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD94486.1 - 0.00065 19.2 0.0 0.0016 18.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain 23S_rRNA_IVP PF05635.6 EGD94486.1 - 0.025 14.4 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein SPX PF03105.14 EGD94487.1 - 3.3e-35 122.1 0.0 4.8e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EGD94487.1 - 9.2e-07 28.6 10.5 9.2e-07 28.6 7.3 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EGD94487.1 - 5e-06 26.2 12.5 1.1e-05 25.1 8.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGD94487.1 - 5.2e-06 26.0 10.1 1.3e-05 24.8 7.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD94487.1 - 1.9e-05 24.2 10.8 4.8e-05 22.9 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD94487.1 - 2.2e-05 24.0 9.8 4.3e-05 23.0 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD94487.1 - 0.00012 22.0 12.4 0.00026 20.9 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGD94487.1 - 0.0079 16.0 3.4 0.018 14.9 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 EGD94487.1 - 0.011 15.6 1.0 0.024 14.5 0.7 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.1 EGD94487.1 - 0.019 14.5 3.1 0.019 14.5 2.2 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EGD94487.1 - 0.043 13.9 5.2 0.1 12.6 3.6 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EGD94487.1 - 0.048 13.3 10.7 0.13 11.9 7.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 EGD94487.1 - 0.082 12.4 10.0 0.16 11.4 6.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-P11 PF03854.9 EGD94487.1 - 0.34 10.3 8.1 8.3 5.9 5.8 2.3 1 1 1 2 2 2 0 P-11 zinc finger DUF3347 PF11827.3 EGD94487.1 - 0.8 9.6 3.7 0.54 10.2 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Peptidase_C12 PF01088.16 EGD94488.1 - 2.6e-63 213.0 0.1 3.9e-63 212.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 I-set PF07679.11 EGD94489.1 - 0.00073 19.3 0.0 0.3 10.9 0.0 3.9 5 0 0 5 5 5 1 Immunoglobulin I-set domain DUF1918 PF08940.6 EGD94489.1 - 0.0033 16.7 0.3 20 4.6 0.0 4.7 5 0 0 5 5 5 2 Domain of unknown function (DUF1918) Nrap PF03813.9 EGD94490.1 - 3.3e-296 984.8 0.0 3.8e-296 984.6 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Fibroin_P25 PF07294.6 EGD94490.1 - 0.06 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Fibroin P25 Cys_Met_Meta_PP PF01053.15 EGD94491.1 - 1e-32 112.9 0.0 1.3e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Asp_Glu_race PF01177.17 EGD94492.1 - 0.012 15.5 0.1 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase MRP-L20 PF12824.2 EGD94493.1 - 3.5e-58 196.1 2.8 4e-58 195.9 2.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EGD94493.1 - 0.0065 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Neugrin APH PF01636.18 EGD94494.1 - 9.3e-05 22.2 0.1 9.3e-05 22.2 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGD94494.1 - 0.00058 19.0 0.0 0.00099 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HSDR_N_2 PF13588.1 EGD94494.1 - 0.0019 17.9 0.0 0.7 9.7 0.0 2.4 1 1 1 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.15 EGD94494.1 - 0.0066 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 EGD94494.1 - 0.09 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Peptidase_M20 PF01546.23 EGD94496.1 - 4.7e-29 101.2 0.0 8.5e-29 100.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGD94496.1 - 1.6e-13 50.4 0.0 2.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain CobS_N PF12556.3 EGD94496.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal Methyltransf_25 PF13649.1 EGD94498.1 - 1.8e-11 44.2 0.0 4.1e-11 43.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD94498.1 - 4.4e-06 26.3 0.0 8e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD94498.1 - 5.5e-05 23.1 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD94498.1 - 0.0001 22.7 0.0 0.00023 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD94498.1 - 0.00011 22.6 0.0 0.00026 21.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD94498.1 - 0.00035 21.1 0.0 0.00086 19.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.20 EGD94499.1 - 3.4e-19 69.3 0.2 7e-19 68.3 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGD94499.1 - 1.2e-05 25.1 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGD94499.1 - 0.00043 19.2 0.0 0.00059 18.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EGD94499.1 - 0.063 13.0 0.2 0.063 13.0 0.2 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AMP-binding PF00501.23 EGD94500.1 - 2.1e-75 253.7 0.0 2.9e-75 253.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGD94500.1 - 7.2e-33 113.7 0.0 1.1e-31 109.8 0.0 2.2 2 0 0 2 2 2 1 Condensation domain PP-binding PF00550.20 EGD94500.1 - 1.2e-08 35.1 0.3 3.2e-08 33.7 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD94500.1 - 0.00013 22.7 0.0 0.00045 21.1 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.17 EGD94501.1 - 1.4e-66 224.9 0.0 1.8e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4296 PF14129.1 EGD94501.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) NmrA PF05368.8 EGD94502.1 - 3.4e-42 144.3 0.0 4.7e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD94502.1 - 4.3e-14 52.9 0.0 6.3e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EGD94502.1 - 0.00016 21.9 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGD94502.1 - 0.0069 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EGD94502.1 - 0.014 14.0 0.0 0.042 12.5 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EGD94502.1 - 0.015 15.7 0.2 0.1 13.0 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EGD94502.1 - 0.05 13.0 0.0 0.12 11.7 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.17 EGD94502.1 - 0.079 13.4 0.1 0.22 12.0 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EGD94502.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EGD94502.1 - 0.15 11.7 0.0 0.42 10.2 0.0 1.7 2 0 0 2 2 2 0 KR domain AMP-binding PF00501.23 EGD94503.1 - 5.6e-75 252.2 0.0 7.5e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EGD94503.1 - 1.5e-57 194.3 0.0 2.3e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EGD94503.1 - 4.8e-12 45.9 0.2 1e-11 44.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EGD94503.1 - 1.5e-09 37.6 0.0 9.5e-09 35.0 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD94503.1 - 1.8e-05 23.5 0.0 7e-05 21.6 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EGD94503.1 - 0.0011 19.8 0.0 0.0032 18.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_2 PF00891.13 EGD94504.1 - 3.6e-43 147.5 0.0 4.8e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EGD94504.1 - 7e-05 23.2 0.0 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD94504.1 - 0.076 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EGD94504.1 - 0.15 12.6 0.0 0.41 11.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGD94505.1 - 9.8e-10 38.7 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD94505.1 - 8.9e-07 29.3 0.0 1.6e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD94505.1 - 6e-06 26.6 0.0 1.5e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD94505.1 - 6.5e-06 26.6 0.1 1.7e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD94505.1 - 0.0001 21.9 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD94505.1 - 0.0003 20.8 0.2 0.001 19.0 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD94505.1 - 0.00045 19.9 0.0 0.003 17.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EGD94505.1 - 0.037 13.1 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MFS_1 PF07690.11 EGD94506.1 - 7.2e-47 159.7 29.7 1.8e-40 138.7 17.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGD94506.1 - 5.9e-06 25.9 1.8 0.56 10.0 0.0 4.1 2 2 1 3 3 3 2 MFS_1 like family OATP PF03137.15 EGD94506.1 - 2.1 6.2 9.3 2.2 6.2 0.0 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family UPRTase PF14681.1 EGD94507.1 - 1.5e-22 79.8 0.0 2.4e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.1 EGD94507.1 - 9.9e-08 32.3 0.0 2.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EGD94507.1 - 4.9e-06 25.7 0.0 9.1e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_17 PF13207.1 EGD94507.1 - 1.1e-05 26.2 0.0 4e-05 24.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EGD94507.1 - 7e-05 22.8 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain HAD PF12710.2 EGD94507.1 - 0.00027 21.1 0.0 0.00053 20.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Arch_ATPase PF01637.13 EGD94507.1 - 0.0023 17.6 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EGD94507.1 - 0.0035 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD94507.1 - 0.0039 16.2 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin SRP54 PF00448.17 EGD94507.1 - 0.0059 16.0 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain G-alpha PF00503.15 EGD94507.1 - 0.0071 15.0 0.0 0.0089 14.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit NB-ARC PF00931.17 EGD94507.1 - 0.008 15.0 0.1 0.03 13.1 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.1 EGD94507.1 - 0.0083 15.9 0.1 0.027 14.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGD94507.1 - 0.015 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 EGD94507.1 - 0.015 14.7 0.1 0.045 13.1 0.1 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EGD94507.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Hydrolase_3 PF08282.7 EGD94507.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA_14 PF13173.1 EGD94507.1 - 0.02 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EGD94507.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.7 EGD94507.1 - 0.032 13.8 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Virul_Fac PF10139.4 EGD94507.1 - 0.035 12.0 0.0 0.05 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor PduV-EutP PF10662.4 EGD94507.1 - 0.037 13.5 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.7 EGD94507.1 - 0.038 13.2 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein DUF258 PF03193.11 EGD94507.1 - 0.039 13.1 0.0 0.12 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 S6PP PF05116.8 EGD94507.1 - 0.042 13.1 0.4 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase SKI PF01202.17 EGD94507.1 - 0.048 13.5 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase AAA_28 PF13521.1 EGD94507.1 - 0.074 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hydrolase PF00702.21 EGD94507.1 - 0.083 13.2 0.0 0.39 11.1 0.0 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase AAA_5 PF07728.9 EGD94507.1 - 0.099 12.3 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PEPCK_ATP PF01293.15 EGD94507.1 - 0.11 11.0 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase PRK PF00485.13 EGD94507.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 EGD94507.1 - 0.14 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PRELI PF04707.9 EGD94508.1 - 5.1e-23 81.3 0.0 4e-20 71.9 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family Cyt_c_ox_IV PF12270.3 EGD94508.1 - 0.14 11.9 0.1 0.47 10.2 0.0 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV His_Phos_1 PF00300.17 EGD94509.1 - 5.4e-31 107.8 0.1 6.3e-31 107.6 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.20 EGD94510.1 - 1.5e-72 243.9 0.0 2e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94510.1 - 5.6e-37 127.2 0.0 7.7e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EGD94510.1 - 1.6e-11 44.2 0.0 3.4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EGD94510.1 - 3.1e-06 26.3 0.0 1.3e-05 24.3 0.0 1.8 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EGD94510.1 - 7.7e-05 22.1 0.2 0.00014 21.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EGD94510.1 - 0.0015 17.2 0.1 0.0022 16.6 0.1 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EGD94510.1 - 0.02 14.6 2.2 0.054 13.2 0.0 2.6 2 1 0 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGD94510.1 - 0.11 11.3 0.5 0.17 10.7 0.4 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EGD94510.1 - 0.16 10.7 0.3 0.25 10.0 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MARVEL PF01284.18 EGD94511.1 - 3.3e-23 82.1 8.5 4e-23 81.8 5.9 1.0 1 0 0 1 1 1 1 Membrane-associating domain Fig1 PF12351.3 EGD94511.1 - 1 9.2 5.8 0.61 9.9 2.8 1.5 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF2306 PF10067.4 EGD94511.1 - 2.1 8.5 5.6 4.9 7.3 1.5 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) DUF4551 PF15087.1 EGD94514.1 - 1.6 6.9 5.9 2.2 6.5 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) His_Phos_1 PF00300.17 EGD94517.1 - 1.9e-19 70.2 0.0 2.6e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M28 PF04389.12 EGD94518.1 - 7e-28 97.5 0.2 1.1e-27 96.8 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M28 NO_synthase PF02898.10 EGD94518.1 - 0.025 13.2 0.5 0.38 9.3 0.0 2.0 2 0 0 2 2 2 0 Nitric oxide synthase, oxygenase domain Peptidase_M20 PF01546.23 EGD94518.1 - 0.038 13.4 0.4 0.12 11.8 0.1 1.8 1 1 1 2 2 2 0 Peptidase family M20/M25/M40 FG-GAP_2 PF14312.1 EGD94518.1 - 0.67 10.0 3.6 3.1 7.8 0.1 2.8 3 0 0 3 3 3 0 FG-GAP repeat L_HGMIC_fpl PF10242.4 EGD94519.1 - 0.016 15.2 1.4 0.016 15.2 1.0 2.3 2 1 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein RRM_1 PF00076.17 EGD94520.1 - 3e-52 174.1 0.1 6.2e-20 70.5 0.1 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD94520.1 - 2e-44 149.4 0.0 1.5e-15 56.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD94520.1 - 7.8e-21 73.6 0.0 1.4e-06 28.0 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD94520.1 - 6.9e-07 28.9 0.0 0.00024 20.8 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.6 EGD94520.1 - 0.0082 15.6 0.0 0.6 9.6 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) TPR_14 PF13428.1 EGD94520.1 - 0.018 15.6 0.2 6.4 7.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Lsm_interact PF05391.6 EGD94520.1 - 0.28 10.6 1.8 0.45 10.0 0.1 2.2 2 0 0 2 2 2 0 Lsm interaction motif FRG2 PF15315.1 EGD94521.1 - 0.081 12.8 6.8 0.09 12.7 4.7 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 PBP1_TM PF14812.1 EGD94521.1 - 0.83 10.0 6.4 1 9.7 4.4 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Gag_spuma PF03276.9 EGD94521.1 - 6.9 4.8 8.5 7.4 4.7 5.9 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DEAD PF00270.24 EGD94523.1 - 3.8e-44 150.1 0.0 8.1e-44 149.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGD94523.1 - 2.1e-22 78.4 0.2 4.4e-22 77.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGD94523.1 - 3.2e-21 74.9 0.0 8.1e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGD94523.1 - 0.26 11.4 1.1 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain Ribosomal_L22 PF00237.14 EGD94524.1 - 2.2e-16 59.6 0.3 2.5e-08 33.7 0.1 2.4 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e Mrr_N PF14338.1 EGD94524.1 - 0.0069 16.4 1.7 0.0098 15.9 0.2 2.1 2 0 0 2 2 2 1 Mrr N-terminal domain DUF4054 PF13262.1 EGD94524.1 - 0.14 12.3 0.4 2.9 8.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) Oxysterol_BP PF01237.13 EGD94525.1 - 2.6e-51 174.1 0.0 2.3e-43 148.0 0.0 2.2 1 1 1 2 2 2 2 Oxysterol-binding protein AUX_IAA PF02309.11 EGD94525.1 - 1.4 8.6 5.8 0.58 9.8 2.3 1.5 2 0 0 2 2 2 0 AUX/IAA family Cnd1_N PF12922.2 EGD94526.1 - 3.7e-57 192.6 0.0 1.2e-56 190.9 0.0 2.0 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 EGD94526.1 - 5.8e-53 179.3 10.5 3.9e-51 173.4 1.3 3.3 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGD94526.1 - 5.7e-10 39.3 8.6 0.00011 22.3 0.0 6.0 4 2 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EGD94526.1 - 1.2e-07 31.2 9.9 0.23 11.6 0.0 7.1 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 EGD94526.1 - 8.2e-06 26.1 6.0 0.2 12.1 0.0 6.2 5 0 0 5 5 5 2 HEAT-like repeat DUF2435 PF10363.4 EGD94526.1 - 0.0001 22.1 0.1 6 6.8 0.0 4.6 3 1 1 4 4 4 2 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 EGD94526.1 - 0.026 14.5 2.0 17 5.4 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.2 EGD94526.1 - 0.42 9.5 10.0 0.053 12.5 1.1 3.6 4 2 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain Pkinase PF00069.20 EGD94527.1 - 1.5e-41 142.2 0.0 6.7e-25 87.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94527.1 - 3.2e-15 55.8 0.0 3.2e-11 42.8 0.0 2.1 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGD94527.1 - 0.00078 18.4 0.0 0.59 9.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGD94527.1 - 0.0053 16.5 0.1 0.41 10.3 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Toprim_N PF08275.6 EGD94527.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain PCMT PF01135.14 EGD94528.1 - 2.1e-61 207.1 0.0 2.6e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGD94528.1 - 5.6e-10 39.7 0.0 8.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD94528.1 - 1.7e-07 30.9 0.1 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD94528.1 - 3.4e-06 26.8 0.0 5.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD94528.1 - 6.9e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGD94528.1 - 7.9e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD94528.1 - 0.00037 20.9 0.0 0.00058 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD94528.1 - 0.0018 17.6 0.0 0.0033 16.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGD94528.1 - 0.0098 16.2 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD94528.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EGD94528.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 EGD94528.1 - 0.03 13.4 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EGD94528.1 - 0.031 13.3 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 EGD94528.1 - 0.045 14.5 0.1 0.2 12.5 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.6 EGD94528.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DnaJ PF00226.26 EGD94529.1 - 6.2e-25 86.7 1.5 1.7e-24 85.2 1.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 EGD94529.1 - 5e-22 77.3 3.3 3.2e-09 36.3 0.1 5.4 3 2 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 EGD94529.1 - 4.8e-19 66.6 1.9 0.00029 20.5 0.0 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGD94529.1 - 1.3e-17 62.5 0.9 8e-06 25.2 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGD94529.1 - 1.4e-15 56.3 0.4 0.045 14.3 0.1 7.3 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGD94529.1 - 1.8e-13 50.1 1.0 0.0018 18.0 0.0 4.8 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGD94529.1 - 7.9e-12 45.5 4.1 2.7e-05 24.7 0.1 5.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGD94529.1 - 6.4e-11 41.2 1.4 0.0089 15.7 0.0 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGD94529.1 - 5.2e-09 36.3 2.8 0.078 13.3 0.5 4.9 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGD94529.1 - 3e-07 30.1 3.0 0.032 14.4 0.0 6.3 6 2 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGD94529.1 - 3.4e-07 30.2 6.2 5.7 7.6 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 EGD94529.1 - 4.6e-05 23.4 5.4 0.43 10.7 0.0 4.8 4 2 4 8 8 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGD94529.1 - 0.00013 21.8 2.5 0.8 9.6 0.0 5.0 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD94529.1 - 0.0021 17.7 2.8 17 5.4 0.0 5.3 7 0 0 7 7 5 0 Tetratricopeptide repeat DUF3856 PF12968.2 EGD94529.1 - 0.016 15.0 3.4 6.2 6.6 0.0 4.1 4 2 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_20 PF14561.1 EGD94529.1 - 0.045 13.8 0.6 6.9 6.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGD94529.1 - 0.054 13.3 2.2 6.1 6.8 0.0 4.1 4 2 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat SLS PF14611.1 EGD94529.1 - 0.084 12.2 0.4 0.16 11.3 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator RF-1 PF00472.15 EGD94530.1 - 2.5e-33 114.2 0.9 6.1e-33 113.0 0.7 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EGD94530.1 - 7.5e-27 93.3 0.0 3.9e-26 91.0 0.0 2.1 2 0 0 2 2 2 1 PCRF domain HHA PF05321.6 EGD94530.1 - 0.31 11.1 2.7 14 5.8 0.0 3.1 3 0 0 3 3 3 0 Haemolysin expression modulating protein Abdominal-A PF12407.3 EGD94530.1 - 1.3 8.5 7.6 3 7.4 5.3 1.5 1 0 0 1 1 1 0 Homeobox protein Mito_carr PF00153.22 EGD94531.1 - 2.7e-59 196.8 3.9 1e-24 86.0 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Helicase_C PF00271.26 EGD94532.1 - 5.6e-24 83.8 0.1 9.1e-24 83.1 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD94532.1 - 9.3e-17 61.0 0.0 1.3e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2454 PF10521.4 EGD94532.1 - 0.065 12.2 1.1 0.27 10.1 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2454) CMS1 PF14617.1 EGD94532.1 - 0.072 12.1 0.1 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit COX14 PF14880.1 EGD94532.1 - 0.14 11.7 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly SMC_N PF02463.14 EGD94533.1 - 1.1e-22 80.3 2.1 4.1e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGD94533.1 - 5.9e-13 49.6 12.5 5.9e-13 49.6 8.6 4.5 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EGD94533.1 - 1.8e-08 34.7 0.2 4.9e-05 23.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGD94533.1 - 0.00025 20.8 0.0 0.00074 19.3 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EGD94533.1 - 0.00026 20.4 0.0 0.00093 18.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EGD94533.1 - 0.0004 19.5 0.1 0.0004 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 EGD94533.1 - 0.087 13.1 0.2 0.087 13.1 0.2 4.9 3 2 0 3 3 3 0 ABC transporter Reo_sigmaC PF04582.7 EGD94533.1 - 1.6 7.7 8.4 0.48 9.5 0.3 2.6 2 1 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 EGD94533.1 - 4 6.9 54.5 0.54 9.8 3.5 4.9 2 2 2 4 4 4 0 IncA protein NUDIX PF00293.23 EGD94534.1 - 4.1e-13 49.1 0.3 1.2e-12 47.5 0.2 1.7 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EGD94534.1 - 0.0032 16.8 0.0 0.026 13.9 0.0 2.1 2 1 0 2 2 2 1 NUDIX domain DUF3393 PF11873.3 EGD94536.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) SNARE PF05739.14 EGD94537.1 - 4e-17 61.6 0.5 4e-17 61.6 0.4 2.9 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 EGD94537.1 - 5.9e-16 58.5 4.7 2.3e-15 56.6 0.1 3.2 3 0 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 EGD94537.1 - 0.0072 15.8 4.2 0.015 14.8 0.2 2.5 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.7 EGD94537.1 - 0.065 13.4 2.9 7.9 6.8 0.1 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.4 EGD94537.1 - 0.31 10.9 3.1 17 5.3 0.0 3.3 4 0 0 4 4 4 0 Uncharacterized conserved protein Syntaxin-18_N PF10496.4 EGD94537.1 - 0.41 10.5 3.9 0.88 9.4 0.1 3.0 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus SUR7 PF06687.7 EGD94538.1 - 4.4e-09 36.2 0.0 5.8e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family AAA_10 PF12846.2 EGD94539.1 - 5.8e-07 29.2 0.1 0.0034 16.8 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EGD94539.1 - 0.006 16.0 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EGD94539.1 - 0.035 14.2 0.1 6.4 6.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 EGD94539.1 - 0.036 13.8 0.0 9.7 5.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 Glyco_hydro_18 PF00704.23 EGD94540.1 - 4.9e-17 62.3 2.6 3.3e-16 59.6 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 adh_short PF00106.20 EGD94541.1 - 2.3e-28 99.2 0.5 2.8e-28 98.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD94541.1 - 1.3e-12 47.7 0.1 2.2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD94541.1 - 3.3e-05 23.4 0.1 0.00015 21.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGD94541.1 - 7.7e-05 21.7 0.0 8.4e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.5 EGD94541.1 - 0.025 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EGD94541.1 - 0.036 13.8 0.1 0.091 12.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EGD94541.1 - 0.058 13.3 0.5 0.28 11.1 0.4 2.0 1 1 0 1 1 1 0 NADH(P)-binding Ion_trans_2 PF07885.11 EGD94542.1 - 6.4e-24 83.4 24.4 1.6e-14 53.3 5.2 3.3 3 0 0 3 3 3 2 Ion channel PTR2 PF00854.16 EGD94544.1 - 1e-28 100.2 9.2 1.4e-28 99.7 6.4 1.2 1 0 0 1 1 1 1 POT family ATP-grasp_4 PF13535.1 EGD94545.1 - 8.9e-20 71.1 0.0 1.6e-17 63.8 0.0 2.6 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGD94545.1 - 8.3e-08 31.8 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EGD94545.1 - 1.5e-05 23.8 0.0 0.0013 17.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EGD94545.1 - 0.00028 20.7 0.0 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGD94545.1 - 0.0004 19.7 0.0 0.0011 18.2 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RTA1 PF04479.8 EGD94547.1 - 2.5e-45 154.7 5.4 3.7e-45 154.1 3.8 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3040 PF11239.3 EGD94547.1 - 0.22 11.5 8.5 0.17 11.9 0.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) SecG PF03840.9 EGD94547.1 - 1.8 8.3 7.6 6.6 6.5 0.1 3.3 3 0 0 3 3 3 0 Preprotein translocase SecG subunit DctQ PF04290.7 EGD94547.1 - 1.9 8.2 19.5 6.1 6.6 3.2 3.2 2 1 2 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component PGG PF13962.1 EGD94547.1 - 2.5 7.7 10.5 0.051 13.1 1.2 2.5 2 2 1 3 3 3 0 Domain of unknown function NfeD PF01957.13 EGD94547.1 - 2.8 8.0 7.8 0.38 10.8 0.1 3.0 2 2 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF3433 PF11915.3 EGD94548.1 - 8.7e-30 102.7 22.8 6.3e-25 87.1 2.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Pkinase PF00069.20 EGD94549.1 - 8e-27 94.0 0.0 1.1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94549.1 - 1.5e-10 40.5 0.2 2.9e-09 36.3 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGD94550.1 - 1.1e-28 100.1 0.0 1.4e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94550.1 - 4.9e-11 42.1 0.0 5.9e-10 38.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.17 EGD94551.1 - 2.1e-10 40.0 0.0 0.0003 20.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 EGD94551.1 - 1.8e-09 37.2 3.1 4e-09 36.1 2.1 1.6 1 0 0 1 1 1 1 G-patch domain RRM_6 PF14259.1 EGD94551.1 - 2.9e-09 36.7 0.0 0.0016 18.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 EGD94551.1 - 4e-09 35.4 1.1 6.2e-09 34.7 0.8 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.2 EGD94551.1 - 0.00051 19.8 1.7 0.00051 19.8 1.2 2.2 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_5 PF13893.1 EGD94551.1 - 0.044 13.6 0.0 0.35 10.7 0.0 2.4 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad50_zn_hook PF04423.9 EGD94551.1 - 0.05 13.0 0.2 0.14 11.6 0.2 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif SLAC1 PF03595.12 EGD94554.1 - 1.3e-102 342.8 56.3 1.5e-102 342.6 39.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MoaE PF02391.12 EGD94555.1 - 4.1e-28 97.5 0.0 5e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SCO1-SenC PF02630.9 EGD94556.1 - 6.1e-53 178.9 0.0 8.1e-53 178.5 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 EGD94556.1 - 0.004 17.2 0.0 0.0067 16.5 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EGD94556.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family MFS_1 PF07690.11 EGD94558.1 - 1.1e-28 99.9 25.6 1.1e-28 99.9 17.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily HNH_2 PF13391.1 EGD94559.1 - 1.2e-11 44.2 0.1 2.7e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease ABC_tran PF00005.22 EGD94562.1 - 1.5e-52 177.4 0.0 3.9e-32 111.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGD94562.1 - 2.3e-24 86.2 20.7 1.2e-23 83.8 5.6 3.3 2 1 1 3 3 3 1 ABC transporter transmembrane region AAA_21 PF13304.1 EGD94562.1 - 3.8e-10 40.2 0.0 0.33 10.8 0.0 4.5 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EGD94562.1 - 1.4e-08 34.9 0.0 0.003 17.5 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EGD94562.1 - 3.1e-08 33.1 2.4 0.014 14.5 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGD94562.1 - 1.1e-07 31.2 0.7 0.011 15.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EGD94562.1 - 1.8e-06 28.0 1.5 0.094 12.8 0.0 3.9 3 2 0 3 3 3 2 AAA domain DUF87 PF01935.12 EGD94562.1 - 5.9e-06 26.2 7.9 0.00056 19.7 0.2 3.2 3 0 0 3 3 3 2 Domain of unknown function DUF87 Miro PF08477.8 EGD94562.1 - 1.7e-05 25.2 0.5 0.038 14.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EGD94562.1 - 1.8e-05 24.0 1.3 0.09 11.9 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGD94562.1 - 2.4e-05 23.8 0.1 0.11 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EGD94562.1 - 7.6e-05 21.7 1.7 0.18 10.7 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_10 PF12846.2 EGD94562.1 - 7.7e-05 22.2 0.7 0.18 11.2 0.4 2.4 2 0 0 2 2 2 2 AAA-like domain Dynamin_N PF00350.18 EGD94562.1 - 9.5e-05 22.2 0.6 0.03 14.1 0.0 2.6 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 EGD94562.1 - 0.00019 20.9 0.8 0.31 10.4 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 EGD94562.1 - 0.00043 20.6 0.7 0.88 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGD94562.1 - 0.00048 20.9 0.4 2.3 9.0 0.2 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EGD94562.1 - 0.0005 20.0 0.0 0.64 9.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EGD94562.1 - 0.0011 19.2 0.1 2.2 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EGD94562.1 - 0.0014 17.5 0.0 0.024 13.4 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain MobB PF03205.9 EGD94562.1 - 0.0027 17.4 0.5 0.72 9.5 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGD94562.1 - 0.0047 16.8 0.1 3.3 7.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGD94562.1 - 0.0057 15.7 0.3 0.89 8.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin SbcCD_C PF13558.1 EGD94562.1 - 0.0058 16.5 0.1 4.7 7.2 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.8 EGD94562.1 - 0.015 14.2 0.1 1.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EGD94562.1 - 0.016 14.3 0.2 0.99 8.5 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 EGD94562.1 - 0.017 14.6 0.6 2.9 7.3 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 EGD94562.1 - 0.018 14.6 0.7 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EGD94562.1 - 0.028 14.1 0.2 1 9.0 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 EGD94562.1 - 0.035 14.2 0.1 6.9 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase cobW PF02492.14 EGD94562.1 - 0.04 13.3 1.8 1.1 8.6 0.3 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 EGD94562.1 - 0.066 11.8 0.8 4.4 5.8 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Adeno_IVa2 PF02456.10 EGD94562.1 - 0.078 11.6 0.1 4.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_14 PF13173.1 EGD94562.1 - 0.11 12.4 0.1 11 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 EGD94562.1 - 0.16 11.3 1.5 25 4.2 0.0 3.0 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.4 EGD94562.1 - 0.74 8.3 4.7 3.7 6.0 0.1 3.0 4 0 0 4 4 4 0 Predicted ATPase of the ABC class DUF3459 PF11941.3 EGD94563.1 - 0.093 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) AMP-binding PF00501.23 EGD94564.1 - 5e-160 532.4 0.1 2e-77 260.3 0.0 5.2 4 2 2 6 6 6 4 AMP-binding enzyme Condensation PF00668.15 EGD94564.1 - 1.1e-106 356.1 0.0 1.7e-35 122.3 0.0 4.3 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 EGD94564.1 - 1.5e-24 85.9 0.2 2.2e-13 50.2 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD94564.1 - 6.4e-08 33.4 0.1 6.5e-05 23.7 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain HAUS5 PF14817.1 EGD94564.1 - 0.2 10.1 0.0 0.35 9.3 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Amidase PF01425.16 EGD94565.1 - 9.6e-39 133.4 0.9 1.8e-38 132.5 0.3 1.6 2 0 0 2 2 2 1 Amidase Amino_oxidase PF01593.19 EGD94566.1 - 7.7e-28 97.7 0.7 1.6e-26 93.3 0.5 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGD94566.1 - 1.5e-06 28.0 0.0 3.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGD94566.1 - 0.00081 19.5 0.1 0.0022 18.0 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_4 PF08386.5 EGD94567.1 - 1e-18 67.1 0.0 2.3e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EGD94567.1 - 1.7e-10 40.8 0.0 6e-09 35.7 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGD94567.1 - 0.00023 21.0 0.0 0.00058 19.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Beta-lactamase PF00144.19 EGD94568.1 - 1.8e-45 155.3 0.0 2.5e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EGD94568.1 - 2.5e-11 43.2 0.0 5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Ank_2 PF12796.2 EGD94569.1 - 3.5e-59 197.1 0.0 3.8e-17 62.4 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EGD94569.1 - 1.6e-50 166.4 0.1 8.7e-10 37.9 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EGD94569.1 - 7.8e-40 134.5 1.0 2.9e-09 37.1 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD94569.1 - 1.2e-36 121.0 0.0 1.3e-05 24.9 0.0 7.3 7 0 0 7 7 6 6 Ankyrin repeat Ank_5 PF13857.1 EGD94569.1 - 9.5e-35 117.8 1.1 1.9e-11 43.8 0.1 6.5 1 1 5 6 6 6 5 Ankyrin repeats (many copies) NACHT PF05729.7 EGD94569.1 - 2.9e-12 46.5 0.0 6e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGD94569.1 - 0.0001 22.3 0.0 0.00046 20.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EGD94569.1 - 0.0034 17.2 0.0 0.012 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGD94569.1 - 0.01 16.0 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EGD94569.1 - 0.011 14.5 0.0 0.031 13.1 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EGD94569.1 - 0.016 15.3 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 EGD94569.1 - 0.035 13.0 0.0 0.084 11.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EGD94569.1 - 0.036 14.2 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGD94569.1 - 0.039 13.6 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF2404 PF10296.4 EGD94569.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Zeta_toxin PF06414.7 EGD94569.1 - 0.16 11.0 0.3 0.73 8.8 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Torsin PF06309.6 EGD94569.1 - 0.19 11.6 0.0 0.46 10.3 0.0 1.6 1 0 0 1 1 1 0 Torsin Ank_2 PF12796.2 EGD94571.1 - 1.3e-105 345.8 16.1 1.2e-21 76.8 0.1 6.5 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EGD94571.1 - 2.8e-85 276.1 10.3 1.3e-06 27.8 0.0 14.3 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 EGD94571.1 - 1e-68 226.5 2.4 2.5e-12 46.9 0.0 9.3 7 2 2 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD94571.1 - 1.3e-61 203.2 4.0 7.3e-10 38.7 0.0 12.5 3 1 11 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD94571.1 - 1.9e-59 191.6 4.6 0.00066 19.6 0.0 13.6 13 0 0 13 13 13 12 Ankyrin repeat HbrB PF08539.6 EGD94572.1 - 1.8e-53 180.6 0.0 2.8e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Peptidase_S64 PF08192.6 EGD94575.1 - 0.0034 15.8 0.1 0.22 9.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S32 PF05579.8 EGD94575.1 - 0.0067 15.4 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Trypsin_2 PF13365.1 EGD94575.1 - 0.011 15.7 0.0 0.034 14.1 0.0 1.8 1 1 0 1 1 1 0 Trypsin-like peptidase domain Myb_DNA-bind_3 PF12776.2 EGD94576.1 - 0.00011 22.7 0.5 0.44 11.2 0.0 2.5 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD94576.1 - 0.00039 20.4 0.5 0.24 11.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EGD94576.1 - 0.028 14.2 2.3 0.28 11.1 0.1 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGD94576.1 - 0.039 14.0 2.2 0.22 11.6 1.6 2.2 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF2880 PF11082.3 EGD94576.1 - 8.7 6.3 11.5 2.9 7.8 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2880) AAA PF00004.24 EGD94577.1 - 8.7e-17 61.5 0.1 7.1e-16 58.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGD94577.1 - 5.2e-05 22.9 1.9 6.9e-05 22.5 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EGD94577.1 - 0.00019 21.1 0.0 0.00063 19.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGD94577.1 - 0.00025 21.2 0.4 0.0041 17.2 0.3 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD94577.1 - 0.0035 17.3 0.3 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EGD94577.1 - 0.029 14.2 0.1 0.029 14.2 0.1 2.8 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EGD94577.1 - 0.55 10.5 0.0 0.55 10.5 0.0 4.4 3 1 1 5 5 5 0 AAA domain Ldh_1_C PF02866.13 EGD94579.1 - 2.5e-44 151.0 0.0 3.7e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EGD94579.1 - 1e-41 142.0 0.0 1.5e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EGD94579.1 - 0.00093 17.9 0.0 0.0013 17.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EGD94579.1 - 0.025 13.8 0.0 0.35 10.1 0.1 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.19 EGD94579.1 - 0.12 12.7 0.2 0.75 10.1 0.0 2.5 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain V-SNARE_C PF12352.3 EGD94582.1 - 6.7e-16 58.1 1.0 6.7e-16 58.1 0.7 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EGD94582.1 - 7.7e-06 25.5 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Sec20 BAR_2 PF10455.4 EGD94582.1 - 0.0038 16.2 0.1 0.0049 15.8 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking HTH_DeoR PF08220.7 EGD94582.1 - 0.012 15.1 0.1 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Sigma70_r4 PF04545.11 EGD94582.1 - 0.022 14.0 0.1 0.048 12.9 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HNH_2 PF13391.1 EGD94583.1 - 6.5e-10 38.6 0.0 1.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease ATG11 PF10377.4 EGD94584.1 - 0.043 13.7 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 11 Glyco_hydro_18 PF00704.23 EGD94586.1 - 3.8e-33 115.3 1.8 6.5e-33 114.6 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EGD94586.1 - 7.4e-10 38.5 0.1 3.7e-06 26.7 0.1 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EGD94586.1 - 0.00069 19.5 4.1 0.00069 19.5 2.9 3.1 3 0 0 3 3 3 1 Chitin recognition protein HNH_2 PF13391.1 EGD94587.1 - 2.2e-10 40.1 0.1 1e-09 38.0 0.1 2.1 1 1 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.11 EGD94588.1 - 2.9e-30 105.1 51.3 9.3e-19 67.3 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD94588.1 - 4.4e-09 35.4 27.3 0.00037 19.2 9.3 2.7 1 1 1 2 2 2 2 Sugar (and other) transporter F-box-like PF12937.2 EGD94589.1 - 2.5e-06 27.0 0.1 5.8e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD94589.1 - 0.041 13.5 0.1 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 F-box domain DUF1214 PF06742.6 EGD94590.1 - 0.019 15.4 0.0 0.038 14.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1214) His_Phos_1 PF00300.17 EGD94591.1 - 5.3e-16 59.1 0.0 8.4e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LSM PF01423.17 EGD94592.1 - 7.4e-17 60.6 0.0 1.1e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGD94592.1 - 0.026 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain DSPc PF00782.15 EGD94593.1 - 6.1e-11 42.0 0.0 1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD94593.1 - 8.3e-06 25.3 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGD94593.1 - 0.015 15.5 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EGD94593.1 - 0.027 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.7 EGD94593.1 - 0.034 13.5 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PPR_3 PF13812.1 EGD94594.1 - 6.2e-22 75.9 4.0 0.014 15.6 0.0 9.5 10 0 0 10 10 10 5 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGD94594.1 - 4.1e-17 61.8 0.2 0.1 12.6 0.1 8.2 4 4 5 9 9 9 5 PPR repeat family PPR PF01535.15 EGD94594.1 - 5e-13 48.0 4.9 0.032 14.2 0.0 7.4 9 0 0 9 9 9 4 PPR repeat DUF3312 PF11768.3 EGD94594.1 - 0.011 14.0 0.0 0.018 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Dak1_2 PF13684.1 EGD94594.1 - 0.018 13.9 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Dihydroxyacetone kinase family TPR_9 PF13371.1 EGD94594.1 - 0.052 13.4 0.1 6.2 6.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_1 PF12854.2 EGD94594.1 - 0.85 9.1 2.9 12 5.4 0.0 3.3 4 0 0 4 4 4 0 PPR repeat PLA2_B PF01735.13 EGD94595.1 - 1.3e-27 96.1 0.0 1.8e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Exo70 PF03081.10 EGD94596.1 - 5e-75 252.6 0.0 9.4e-75 251.7 0.0 1.5 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Laminin_II PF06009.7 EGD94596.1 - 0.33 10.6 2.2 3.7 7.3 0.2 2.7 2 0 0 2 2 2 0 Laminin Domain II Ank_2 PF12796.2 EGD94597.1 - 2.4e-32 111.1 0.7 5e-14 52.4 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD94597.1 - 1.2e-26 92.5 10.3 9.1e-11 41.9 0.1 5.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD94597.1 - 2e-24 83.2 4.0 0.00013 21.9 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.25 EGD94597.1 - 2.6e-24 83.7 10.5 2.1e-05 24.0 0.1 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EGD94597.1 - 1.5e-20 72.7 1.0 3.1e-06 27.2 0.0 5.4 3 2 3 6 6 6 5 Ankyrin repeats (many copies) NACHT PF05729.7 EGD94597.1 - 3e-06 27.0 0.0 1e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EGD94597.1 - 0.00017 21.7 0.1 0.00068 19.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD94597.1 - 0.00064 19.7 1.0 0.039 13.9 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain SUI1 PF01253.17 EGD94597.1 - 0.18 11.6 0.1 0.57 10.0 0.0 1.8 2 0 0 2 2 2 0 Translation initiation factor SUI1 BCDHK_Adom3 PF10436.4 EGD94600.1 - 3.1e-29 101.5 0.0 3.7e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase STE2 PF02116.10 EGD94601.1 - 4.7e-77 258.8 21.6 5.2e-77 258.6 15.0 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Metallophos PF00149.23 EGD94602.1 - 7.7e-06 25.4 0.4 1.4e-05 24.6 0.2 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 EGD94604.1 - 8.7e-08 31.6 0.0 1.6e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EGD94604.1 - 2.2e-07 30.1 0.0 0.00057 19.0 0.0 2.9 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD94604.1 - 2.6e-07 30.6 0.0 0.00075 19.3 0.0 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EGD94604.1 - 0.0091 15.0 0.0 0.021 13.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EGD94604.1 - 0.027 13.8 0.0 0.95 8.7 0.0 2.7 3 0 0 3 3 3 0 RIO1 family Choline_kinase PF01633.15 EGD94604.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aldo_ket_red PF00248.16 EGD94605.1 - 1.2e-14 53.7 0.0 1.7e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 EGD94606.1 - 6.7e-53 178.2 1.9 8.1e-53 177.9 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.6 EGD94606.1 - 0.077 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Maf1 PF09174.5 EGD94607.1 - 9.3e-60 201.5 0.1 1.4e-59 200.9 0.1 1.2 1 0 0 1 1 1 1 Maf1 regulator IncA PF04156.9 EGD94608.1 - 2e-05 24.2 35.1 8.4e-05 22.2 4.0 4.5 3 1 1 4 4 4 2 IncA protein Tropomyosin_1 PF12718.2 EGD94608.1 - 0.00026 20.8 28.7 0.00026 20.8 19.9 5.2 5 1 1 6 6 6 2 Tropomyosin like Filament PF00038.16 EGD94608.1 - 0.066 12.6 53.3 0.04 13.3 23.1 4.1 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 EGD94608.1 - 1.4 7.9 21.1 0.21 10.7 4.3 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EGD94608.1 - 2.3 8.5 18.2 3.4 7.9 3.1 4.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein N2227 PF07942.7 EGD94609.1 - 2e-60 204.0 0.0 2.6e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EGD94609.1 - 0.0015 18.2 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 EGD94611.1 - 3.5e-25 89.2 0.0 4.2e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD94611.1 - 6.2e-08 32.5 0.0 8.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EGD94611.1 - 0.0038 16.0 0.0 0.049 12.4 0.0 2.0 1 1 1 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 EGD94611.1 - 0.0052 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 EGD94611.1 - 0.014 14.2 0.0 0.033 13.0 0.0 1.6 1 1 1 2 2 2 0 Chlorophyllase enzyme PGAP1 PF07819.8 EGD94611.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein COPIIcoated_ERV PF07970.7 EGD94612.1 - 4.8e-32 111.3 0.1 1.1e-30 106.8 0.0 2.2 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGD94612.1 - 8.3e-23 80.1 0.0 1.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) FlgD_ig PF13860.1 EGD94612.1 - 0.13 11.9 0.1 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 FlgD Ig-like domain Pkinase PF00069.20 EGD94613.1 - 3e-33 115.0 0.2 4.7e-33 114.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94613.1 - 3.4e-14 52.5 0.1 5e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD94613.1 - 0.17 11.5 0.0 0.87 9.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2561 PF10812.3 EGD94613.1 - 2.5 7.6 4.5 3.7 7.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Pex24p PF06398.6 EGD94614.1 - 3e-83 279.5 0.1 3.7e-83 279.2 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 EGD94614.1 - 0.0034 15.3 0.1 0.0053 14.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) ATP-synt_8 PF00895.15 EGD94614.1 - 1.8 8.7 7.2 28 4.9 4.1 3.2 2 1 0 2 2 2 0 ATP synthase protein 8 Nop16 PF09420.5 EGD94616.1 - 4e-53 179.8 6.1 4.7e-53 179.6 4.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zip PF02535.17 EGD94617.1 - 3.5e-57 193.8 11.6 2.5e-56 191.0 8.1 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Anp1 PF03452.9 EGD94618.1 - 2.2e-102 341.8 0.0 3.6e-102 341.1 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EGD94618.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Mito_carr PF00153.22 EGD94619.1 - 7e-55 182.7 0.4 5.6e-20 70.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HAD PF12710.2 EGD94620.1 - 0.075 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ank_2 PF12796.2 EGD94621.1 - 2.4e-74 245.7 5.9 2.5e-15 56.5 0.0 7.3 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD94621.1 - 2.8e-54 179.9 9.3 1.6e-09 37.7 0.0 10.5 5 2 6 11 11 11 10 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGD94621.1 - 2.9e-50 167.7 9.2 3.3e-09 37.0 0.1 11.3 3 1 8 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD94621.1 - 3.7e-48 156.6 3.7 0.0075 16.4 0.0 13.8 14 0 0 14 14 14 9 Ankyrin repeat Ank PF00023.25 EGD94621.1 - 5.4e-48 158.4 13.4 0.00044 19.9 0.1 13.8 13 1 0 13 13 13 10 Ankyrin repeat Chorismate_bind PF00425.13 EGD94622.1 - 5.1e-85 284.8 0.0 8.2e-85 284.2 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EGD94622.1 - 9.6e-38 129.5 0.0 1.5e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EGD94622.1 - 4.6e-11 42.8 0.0 1e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EGD94622.1 - 1e-08 34.9 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 MFS_1 PF07690.11 EGD94623.1 - 1.9e-36 125.5 26.8 2.9e-36 124.9 18.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DHDPS PF00701.17 EGD94625.1 - 2.1e-44 151.2 0.0 2.4e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2014 PF09427.5 EGD94626.1 - 6.6e-103 343.3 0.4 9.8e-103 342.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EGD94626.1 - 4e-18 64.8 1.9 8.1e-18 63.8 1.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain E1-E2_ATPase PF00122.15 EGD94627.1 - 1.1e-64 217.6 6.9 2.3e-64 216.5 4.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD94627.1 - 2.2e-31 108.7 4.4 2.2e-31 108.7 3.0 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD94627.1 - 2.5e-27 96.6 0.3 9.2e-23 81.7 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD94627.1 - 8.7e-18 63.5 0.1 6.4e-17 60.7 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGD94627.1 - 3.1e-13 49.4 0.0 6.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGD94627.1 - 2.1e-12 47.6 0.0 6.9e-12 45.9 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD94627.1 - 2e-05 24.3 1.5 2e-05 24.3 1.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNase_PH PF01138.16 EGD94628.1 - 0.055 13.7 0.1 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 Glyco_hydro_79n PF03662.9 EGD94628.1 - 0.079 11.5 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain Pro-kuma_activ PF09286.6 EGD94630.1 - 7.5e-36 123.2 0.0 1.3e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGD94630.1 - 2.1e-11 43.5 0.4 3e-11 42.9 0.3 1.4 1 1 0 1 1 1 1 Subtilase family NAD_kinase PF01513.16 EGD94631.1 - 1.5e-57 194.5 0.0 2.5e-56 190.5 0.0 2.1 1 1 0 1 1 1 1 ATP-NAD kinase DAO PF01266.19 EGD94632.1 - 1e-38 133.2 0.1 5.4e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EGD94632.1 - 0.025 13.5 0.0 0.18 10.6 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGD94632.1 - 0.16 11.7 0.1 0.58 9.9 0.0 2.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGD94632.1 - 0.2 11.7 0.9 0.35 10.9 0.1 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GAF_2 PF13185.1 EGD94633.1 - 2.3e-07 31.4 0.0 3.4e-07 30.8 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EGD94633.1 - 2.9e-05 24.2 0.0 3.1e-05 24.1 0.0 1.2 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EGD94633.1 - 0.0029 17.6 0.0 0.0035 17.4 0.0 1.4 1 1 0 1 1 1 1 GAF domain DEAD PF00270.24 EGD94634.1 - 6.4e-34 116.8 0.9 1.3e-32 112.5 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD94634.1 - 5.8e-22 77.3 0.2 1.4e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGD94634.1 - 0.063 13.4 0.1 0.3 11.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 EGD94634.1 - 0.082 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) SH3_9 PF14604.1 EGD94635.1 - 5.7e-24 83.4 0.5 1e-11 44.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EGD94635.1 - 9e-16 57.0 0.2 9.9e-07 28.0 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 EGD94635.1 - 5.3e-15 54.8 5.2 8.4e-15 54.2 3.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FCH PF00611.18 EGD94635.1 - 5.8e-15 55.2 0.0 5.8e-15 55.2 0.0 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 EGD94635.1 - 3.9e-07 29.4 0.0 0.00015 21.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Tup_N PF08581.5 EGD94635.1 - 5.1 7.3 13.2 0.032 14.4 1.4 2.9 3 0 0 3 3 3 0 Tup N-terminal Glyco_hydro_72 PF03198.9 EGD94636.1 - 2.7e-135 450.4 2.9 3.2e-135 450.1 2.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EGD94636.1 - 1.9e-07 30.6 0.4 7.2e-07 28.6 0.3 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Arf PF00025.16 EGD94637.1 - 8.5e-74 246.5 0.1 1e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGD94637.1 - 1.1e-11 44.2 0.0 1.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGD94637.1 - 1.2e-10 40.9 0.0 1.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EGD94637.1 - 2.5e-10 39.6 0.7 1.3e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGD94637.1 - 9.9e-09 34.6 0.0 1.2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGD94637.1 - 2.8e-08 34.2 0.0 3.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGD94637.1 - 3.7e-06 26.8 0.0 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD94637.1 - 1.3e-05 24.6 0.0 0.0019 17.6 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGD94637.1 - 0.007 15.6 0.5 0.034 13.4 0.3 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3986 PF13143.1 EGD94637.1 - 0.11 12.9 0.2 0.26 11.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Actin PF00022.14 EGD94638.1 - 1.1e-27 96.4 0.0 8.9e-27 93.5 0.0 2.4 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGD94638.1 - 5.6e-06 25.1 0.0 0.0065 15.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Paf1 PF03985.8 EGD94639.1 - 9.9e-40 136.5 3.0 8.1e-24 84.1 0.0 2.9 2 1 0 2 2 2 2 Paf1 LON PF02190.11 EGD94640.1 - 1e-21 77.5 0.0 1.5e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EGD94640.1 - 3.7e-11 42.8 26.8 4.4e-08 33.0 7.1 3.0 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGD94640.1 - 9.8e-11 41.3 21.6 8.7e-06 25.5 4.8 3.2 2 2 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EGD94640.1 - 4.4e-10 39.2 24.6 5e-08 32.6 6.7 2.8 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 EGD94640.1 - 4e-09 36.0 24.6 1.7e-07 30.8 5.5 2.9 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD94640.1 - 1.2e-08 34.4 22.2 7.5e-07 28.7 6.3 3.0 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD94640.1 - 1.9e-08 33.8 23.5 2e-07 30.5 5.3 2.6 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGD94640.1 - 3.3e-06 26.7 23.1 4.1e-05 23.2 1.3 3.6 3 0 0 3 3 3 2 RING-type zinc-finger U-box PF04564.10 EGD94640.1 - 7.6e-05 22.5 1.7 0.0096 15.8 0.1 3.1 3 0 0 3 3 3 1 U-box domain zf-P11 PF03854.9 EGD94640.1 - 0.00093 18.6 6.8 0.00093 18.6 4.7 2.6 2 0 0 2 2 2 1 P-11 zinc finger zf-rbx1 PF12678.2 EGD94640.1 - 0.0066 16.5 2.5 0.0066 16.5 1.7 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EGD94640.1 - 0.16 11.5 22.1 0.02 14.4 4.3 3.7 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EGD94640.1 - 0.85 9.3 8.5 0.96 9.1 0.9 2.5 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 EGD94640.1 - 2.1 7.9 14.6 2.2 7.9 1.8 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RICTOR_N PF14664.1 EGD94641.1 - 1.6e-136 454.7 0.6 3.4e-136 453.7 0.4 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EGD94641.1 - 7.9e-91 303.0 0.9 7.2e-88 293.3 0.2 4.2 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EGD94641.1 - 1.8e-43 147.0 0.0 7.3e-43 145.1 0.0 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EGD94641.1 - 9.7e-26 89.5 4.7 2.3e-24 85.1 0.1 4.6 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EGD94641.1 - 1.5e-09 37.4 12.8 5.1e-09 35.7 8.8 2.0 1 0 0 1 1 1 1 Hr1 repeat Arm PF00514.18 EGD94641.1 - 1.1 9.1 4.2 67 3.5 0.1 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Uricase PF01014.13 EGD94642.1 - 1.6e-76 254.9 0.3 1.8e-43 147.9 0.6 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 EGD94642.1 - 0.099 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.13 EGD94643.1 - 5.7e-40 136.3 0.0 7.2e-40 136.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.14 EGD94644.1 - 4.6e-38 130.1 0.3 5.2e-38 130.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 EGD94644.1 - 0.055 10.9 0.0 0.061 10.8 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein AAR2 PF05282.6 EGD94645.1 - 1.7e-80 270.6 0.0 3.4e-44 151.2 0.1 2.0 1 1 1 2 2 2 2 AAR2 protein DUF4604 PF15377.1 EGD94645.1 - 2.2 8.5 5.4 1.2 9.3 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Ribosomal_S11 PF00411.14 EGD94646.1 - 1e-40 138.2 0.4 1.3e-40 138.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PDH PF02153.12 EGD94647.1 - 1.2e-12 47.2 0.0 1.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EGD94647.1 - 8.2e-07 29.3 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EGD94647.1 - 5.7e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EGD94647.1 - 0.0015 17.7 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EGD94647.1 - 0.0029 17.0 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EGD94647.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGD94647.1 - 0.027 14.4 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Rossmann-like PF10727.4 EGD94647.1 - 0.087 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain IlvN PF07991.7 EGD94647.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Cytochrom_B561 PF03188.11 EGD94649.1 - 3.5e-09 36.6 14.2 6.7e-09 35.6 9.8 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EGD94649.1 - 0.0046 16.8 0.0 0.0084 16.0 0.0 1.5 1 0 0 1 1 1 1 DOMON domain DUF4229 PF14012.1 EGD94649.1 - 0.6 10.0 6.8 4.1 7.3 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) NfeD PF01957.13 EGD94649.1 - 2.9 8.0 7.8 0.9 9.6 0.3 2.3 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding RRM_6 PF14259.1 EGD94650.1 - 0.00054 19.8 0.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Paf67 PF10255.4 EGD94651.1 - 3.1e-156 520.3 0.0 3.6e-156 520.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EGD94651.1 - 0.019 14.8 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fe-S_biosyn PF01521.15 EGD94652.1 - 4.4e-10 39.4 0.0 2.5e-08 33.8 0.0 2.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Hemerythrin PF01814.18 EGD94653.1 - 4.8e-12 46.1 0.3 7.3e-12 45.5 0.2 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Lactamase_B PF00753.22 EGD94654.1 - 2.2e-10 40.5 0.0 3.7e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGD94654.1 - 0.00071 19.1 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Aminotran_5 PF00266.14 EGD94655.1 - 1.4e-09 37.1 0.0 3.2e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGD94655.1 - 0.00029 19.9 0.0 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1077 PF06417.7 EGD94656.1 - 2e-53 179.0 1.6 2.4e-53 178.7 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) CopD PF05425.8 EGD94656.1 - 0.079 13.1 0.4 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 Copper resistance protein D TMEM171 PF15471.1 EGD94656.1 - 0.29 9.8 7.9 0.53 9.0 5.5 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Methyltransf_2 PF00891.13 EGD94657.1 - 1.6e-28 99.5 0.1 4.6e-28 98.0 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase HTH_27 PF13463.1 EGD94657.1 - 0.13 12.5 0.1 0.62 10.4 0.0 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain MerC PF03203.9 EGD94658.1 - 1.5 9.1 8.5 0.47 10.8 1.0 2.5 2 1 0 2 2 2 0 MerC mercury resistance protein DUF3754 PF12576.3 EGD94658.1 - 1.9 8.1 4.9 0.28 10.8 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Adaptin_N PF01602.15 EGD94660.1 - 2.4e-122 408.9 8.3 2.7e-122 408.7 5.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGD94660.1 - 1.3e-17 64.2 3.8 4.9e-17 62.3 0.4 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGD94660.1 - 1.6e-16 60.3 5.2 1.5e-10 41.2 0.7 4.5 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EGD94660.1 - 5.2e-10 38.5 4.5 0.0051 16.7 0.0 5.5 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.18 EGD94660.1 - 2.9e-05 23.7 3.3 2.5 8.0 0.0 5.3 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EGD94660.1 - 2.9e-05 23.7 0.1 0.64 9.7 0.0 4.2 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 EGD94660.1 - 0.0017 17.7 2.0 2 7.7 0.0 3.1 2 1 0 2 2 2 2 CLASP N terminal HEAT_EZ PF13513.1 EGD94660.1 - 0.0017 18.7 9.5 0.37 11.3 0.0 6.1 6 1 1 7 7 7 1 HEAT-like repeat RIX1 PF08167.7 EGD94660.1 - 0.035 13.7 0.5 0.52 9.9 0.0 2.6 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis T_hemolysin PF12261.3 EGD94660.1 - 0.092 12.2 0.1 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Thermostable hemolysin SH3_2 PF07653.12 EGD94661.1 - 1.1e-10 40.7 0.0 2.4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGD94661.1 - 3.7e-10 39.0 0.1 7e-10 38.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD94661.1 - 1.6e-09 37.2 0.1 4.6e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain RPAP2_Rtr1 PF04181.8 EGD94662.1 - 1.7e-19 69.6 0.1 2.6e-19 69.0 0.1 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.13 EGD94663.1 - 1.5e-43 147.4 2.2 7.3e-43 145.2 1.5 1.8 1 1 0 1 1 1 1 Ribosomal S17 DUF1347 PF07079.6 EGD94663.1 - 0.025 12.7 0.0 0.029 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) Cryptochrome_C PF12546.3 EGD94663.1 - 0.038 14.6 0.1 0.052 14.2 0.0 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Mit_ribos_Mrp51 PF11709.3 EGD94664.1 - 5.3e-91 305.0 0.0 6.1e-91 304.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit FAT PF02259.18 EGD94665.1 - 7.4e-125 416.5 0.2 1.2e-124 415.8 0.1 1.4 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.3 EGD94665.1 - 3.5e-61 205.8 5.9 1.6e-58 197.2 1.1 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 EGD94665.1 - 1.4e-56 191.5 0.7 2.8e-56 190.6 0.5 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EGD94665.1 - 1e-39 134.6 2.8 4e-39 132.7 0.1 3.6 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EGD94665.1 - 3.4e-20 72.1 7.0 0.00013 22.1 0.0 8.7 7 3 1 9 9 9 5 HEAT repeats HEAT_EZ PF13513.1 EGD94665.1 - 1.1e-15 57.5 6.3 0.0012 19.2 0.0 12.2 10 1 3 13 13 13 3 HEAT-like repeat FATC PF02260.15 EGD94665.1 - 6.4e-15 54.2 0.2 1.5e-14 53.0 0.2 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EGD94665.1 - 6.4e-14 50.7 19.3 0.16 12.1 0.0 11.9 13 0 0 13 13 13 5 HEAT repeat UME PF08064.8 EGD94665.1 - 9.9e-05 22.2 4.7 10 6.1 0.0 6.8 5 2 2 7 7 7 2 UME (NUC010) domain Methyltransf_18 PF12847.2 EGD94667.1 - 3.9e-09 37.0 0.0 6.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD94667.1 - 7.8e-09 35.4 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD94667.1 - 3e-07 30.8 0.0 5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD94667.1 - 8.9e-07 29.3 0.0 3.3e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD94667.1 - 1.8e-06 27.5 0.0 2.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EGD94667.1 - 9.3e-06 25.6 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD94667.1 - 0.0016 18.1 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 EGD94667.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD94667.1 - 0.0031 17.5 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD94667.1 - 0.0036 16.7 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 EGD94667.1 - 0.035 12.9 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Pam16 PF03656.8 EGD94668.1 - 1.1e-35 122.1 0.2 1.3e-35 121.9 0.1 1.0 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.6 EGD94669.1 - 9.1e-97 324.0 0.8 1.2e-96 323.6 0.5 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DAHP_synth_1 PF00793.15 EGD94672.1 - 8.5e-97 323.0 0.0 1e-96 322.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2458 PF10454.4 EGD94673.1 - 6.3e-48 162.4 0.9 8.2e-48 162.0 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DUF1168 PF06658.7 EGD94673.1 - 0.15 11.5 2.3 0.28 10.6 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Ribosomal_L50 PF10501.4 EGD94675.1 - 1.8e-17 63.2 0.0 3.8e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S alpha-hel2 PF14456.1 EGD94675.1 - 0.12 11.0 0.7 0.19 10.4 0.5 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 SAP PF02037.22 EGD94675.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 SAP domain Rtf2 PF04641.7 EGD94676.1 - 1.4e-35 122.7 0.0 1.9e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EGD94676.1 - 1.5e-05 24.4 0.0 3.1e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit ApoO PF09769.4 EGD94676.1 - 0.0076 15.9 0.1 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Apolipoprotein O PRKCSH-like PF12999.2 EGD94677.1 - 2.7e-45 154.0 10.5 1.9e-41 141.5 7.2 2.6 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EGD94677.1 - 1e-27 96.4 0.5 2.8e-27 95.0 0.4 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EGD94677.1 - 8.9e-10 39.2 1.6 2.7e-09 37.7 1.1 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein HMG_box PF00505.14 EGD94677.1 - 0.017 15.3 2.4 0.043 14.0 1.6 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box CorA PF01544.13 EGD94677.1 - 0.04 12.9 2.9 0.071 12.1 2.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3450 PF11932.3 EGD94677.1 - 0.049 12.8 3.9 0.21 10.8 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Ax_dynein_light PF10211.4 EGD94677.1 - 0.089 12.6 7.7 0.075 12.8 3.7 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain AalphaY_MDB PF04611.7 EGD94677.1 - 0.12 12.2 0.6 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region Herpes_UL6 PF01763.11 EGD94677.1 - 0.19 9.8 1.8 0.33 9.0 1.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like V_ATPase_I PF01496.14 EGD94677.1 - 0.94 7.2 3.3 1.7 6.4 2.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 EGD94677.1 - 1 8.2 9.8 1.6 7.5 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pox_A_type_inc PF04508.7 EGD94677.1 - 1.4 8.9 6.0 1.6 8.7 0.3 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat GrpE PF01025.14 EGD94677.1 - 4.3 6.8 11.9 1.6 8.2 5.7 2.1 2 0 0 2 2 2 0 GrpE DUF724 PF05266.9 EGD94677.1 - 5.7 6.5 11.3 1.2 8.6 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PAP_assoc PF03828.14 EGD94679.1 - 1.2e-11 44.3 0.0 2.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EGD94679.1 - 1.4e-08 34.9 0.0 3.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Aldo_ket_red PF00248.16 EGD94680.1 - 3.2e-68 229.6 0.0 4.5e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S16 PF00886.14 EGD94680.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S16 FA_hydroxylase PF04116.8 EGD94681.1 - 4.6e-16 59.2 26.1 5.3e-16 59.0 16.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 EGD94682.1 - 3.3e-18 65.0 0.0 3.3e-18 65.0 0.0 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly Methyltransf_23 PF13489.1 EGD94683.1 - 1.2e-19 70.6 0.0 1.8e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD94683.1 - 1.4e-08 35.0 0.0 6.2e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD94683.1 - 4.3e-08 33.7 0.0 7.1e-07 29.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD94683.1 - 1.5e-07 31.1 0.0 1.6e-06 27.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD94683.1 - 8e-06 26.2 0.0 3.2e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD94683.1 - 0.00034 20.9 0.0 0.0012 19.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD94683.1 - 0.00041 19.5 0.0 0.0009 18.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EGD94683.1 - 0.03 13.8 0.0 0.076 12.5 0.0 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.10 EGD94683.1 - 0.057 12.5 0.0 0.16 11.0 0.0 1.7 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G HP_OMP_2 PF02521.9 EGD94683.1 - 0.1 11.1 0.0 0.17 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative outer membrane protein DUF1250 PF06855.7 EGD94683.1 - 0.13 11.8 2.4 9.3 5.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) HAD_2 PF13419.1 EGD94684.1 - 6.4e-22 78.6 0.0 7.6e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGD94684.1 - 7.2e-11 42.9 0.0 3.3e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGD94684.1 - 7.1e-10 39.3 0.0 9.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD94684.1 - 1.1e-09 37.8 0.1 3.3e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EGD94684.1 - 1.8e-07 31.0 0.0 0.0002 21.1 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EGD94684.1 - 0.002 17.7 0.1 0.39 10.3 0.0 2.9 3 0 0 3 3 3 1 Acid Phosphatase Hydrolase_3 PF08282.7 EGD94684.1 - 0.0043 16.6 0.0 0.13 11.7 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EGD94684.1 - 0.075 12.3 0.0 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Peptidase_M35 PF02102.10 EGD94685.1 - 5.3e-101 337.8 0.8 6.2e-101 337.6 0.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGD94685.1 - 5.2e-05 23.7 0.9 0.00011 22.7 0.6 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Glyco_hydro_32N PF00251.15 EGD94685.1 - 0.038 13.3 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Actin PF00022.14 EGD94686.1 - 1.3e-137 458.4 0.0 1.5e-137 458.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGD94686.1 - 0.053 12.1 0.0 11 4.5 0.0 2.9 3 0 0 3 3 3 0 MreB/Mbl protein ATG22 PF11700.3 EGD94687.1 - 5.3e-202 671.5 18.8 6.1e-202 671.3 13.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EGD94687.1 - 1.6e-06 27.1 49.0 0.0013 17.5 17.9 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Mpp10 PF04006.7 EGD94688.1 - 3.9e-92 309.5 76.6 1.3e-91 307.8 53.1 1.8 1 1 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.4 EGD94689.1 - 3.8e-48 163.2 0.0 4.9e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGD94689.1 - 0.0016 17.8 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EGD94689.1 - 0.0038 16.4 0.1 0.0062 15.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EGD94689.1 - 0.022 15.3 0.0 0.033 14.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EGD94689.1 - 0.025 13.9 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EGD94689.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AhpC-TSA PF00578.16 EGD94691.1 - 2e-22 79.1 0.0 3e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGD94691.1 - 3.6e-12 46.0 0.0 5.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin Spore_coat_CotO PF14153.1 EGD94691.1 - 0.0045 16.4 9.0 0.0071 15.8 5.7 1.7 2 0 0 2 2 2 1 Spore coat protein CotO AhpC-TSA_2 PF13911.1 EGD94691.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme SR-25 PF10500.4 EGD94691.1 - 0.39 10.1 14.7 0.61 9.5 10.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ycf1 PF05758.7 EGD94691.1 - 0.58 7.7 4.9 0.59 7.7 3.4 1.0 1 0 0 1 1 1 0 Ycf1 Paf1 PF03985.8 EGD94691.1 - 1 7.9 8.6 1.3 7.6 6.0 1.1 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.9 EGD94691.1 - 1.8 8.0 13.2 2.6 7.5 9.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NARP1 PF12569.3 EGD94691.1 - 1.8 7.2 16.1 2.5 6.7 11.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Daxx PF03344.10 EGD94691.1 - 2.4 6.5 13.1 2.8 6.3 9.1 1.0 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 EGD94691.1 - 7 6.4 18.6 9.8 5.9 12.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.5 EGD94691.1 - 9.7 5.2 23.3 12 5.0 16.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CH PF00307.26 EGD94692.1 - 3.5e-63 210.3 0.0 2.5e-19 69.3 0.2 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EGD94692.1 - 3.1e-07 30.4 1.0 2.1e-05 24.5 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 EGD94692.1 - 3.4e-05 23.4 0.0 2.7 7.7 0.0 4.1 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_1 PF00036.27 EGD94692.1 - 6.2e-05 22.0 1.3 0.18 11.1 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EGD94692.1 - 0.00043 19.9 0.9 0.019 14.8 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain Hydantoinase_B PF02538.9 EGD94693.1 - 7e-203 674.6 0.0 1.1e-202 674.0 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EGD94693.1 - 1.2e-85 287.2 1.1 2.5e-85 286.1 0.8 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGD94693.1 - 4.4e-57 192.4 1.5 9.5e-56 188.0 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DUF3237 PF11578.3 EGD94693.1 - 0.039 13.2 0.1 0.23 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3237) HSBP1 PF06825.7 EGD94693.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 PC4 PF02229.11 EGD94694.1 - 3.3e-22 77.4 0.1 5.5e-22 76.7 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) RNase_H2-Ydr279 PF09468.5 EGD94694.1 - 1.9 7.5 6.3 0.15 11.2 0.2 1.8 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) MIT PF04212.13 EGD94695.1 - 1.1e-07 31.6 0.2 2.7e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Ubiq_cyt_C_chap PF03981.7 EGD94696.1 - 2.9e-34 117.9 0.3 4.6e-34 117.2 0.2 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Peptidase_M24 PF00557.19 EGD94698.1 - 5e-56 189.5 0.0 6.6e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGD94698.1 - 1.2e-22 79.7 0.0 2.6e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TIP41 PF04176.8 EGD94700.1 - 8.1e-78 259.8 0.0 9.8e-78 259.5 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 EGD94701.1 - 1.6e-56 191.3 0.0 5.6e-39 133.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94701.1 - 3.2e-32 111.6 0.0 2.1e-19 69.6 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGD94701.1 - 9.1e-07 28.1 0.0 5.7e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGD94701.1 - 0.056 12.5 0.1 0.091 11.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M76 PF09768.4 EGD94702.1 - 1.8e-67 226.1 3.1 2.2e-67 225.8 2.2 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EGD94702.1 - 0.0021 17.7 0.6 0.0021 17.7 0.4 1.9 1 1 0 1 1 1 1 SprT-like family Tox-MPTase2 PF15638.1 EGD94702.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 PALP PF00291.20 EGD94703.1 - 7.9e-59 199.3 0.1 9.7e-59 199.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EGD94703.1 - 8.5e-07 28.6 0.0 1.2e-05 25.0 0.0 2.6 2 0 0 2 2 2 1 CBS domain SRPRB PF09439.5 EGD94704.1 - 4.2e-26 91.2 0.1 1.3e-24 86.3 0.1 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EGD94704.1 - 5.7e-07 28.9 0.0 0.0011 18.1 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGD94704.1 - 3.4e-05 23.7 0.0 6.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD94704.1 - 0.0079 16.6 0.1 0.076 13.5 0.1 2.6 2 1 0 2 2 1 1 Miro-like protein SRP54 PF00448.17 EGD94704.1 - 0.02 14.3 0.6 0.26 10.6 0.4 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EGD94704.1 - 0.02 14.8 0.2 0.035 14.0 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 EGD94704.1 - 0.044 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EGD94704.1 - 0.059 12.9 0.4 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EGD94704.1 - 0.094 12.8 0.2 0.19 11.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EGD94704.1 - 0.099 12.1 0.2 11 5.4 0.2 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 EGD94704.1 - 0.13 11.8 0.2 0.59 9.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 EGD94704.1 - 0.16 11.1 0.0 0.32 10.1 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region GPI-anchored PF10342.4 EGD94705.1 - 6.6e-10 39.3 0.1 1.4e-09 38.2 0.0 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 EGD94705.1 - 4.6e-07 30.1 3.3 1e-06 29.0 2.3 1.5 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 AA_kinase PF00696.23 EGD94706.1 - 7e-41 140.3 2.6 1e-40 139.8 1.8 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EGD94706.1 - 3.5e-12 45.8 0.1 4.6e-11 42.2 0.0 2.4 2 0 0 2 2 2 1 PUA domain Pkinase PF00069.20 EGD94707.1 - 3e-41 141.2 0.0 1.5e-40 138.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94707.1 - 4.7e-23 81.5 0.0 7.2e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD94707.1 - 0.0064 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGD94707.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 EGD94707.1 - 0.6 8.8 0.1 0.85 8.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AMP-binding PF00501.23 EGD94708.1 - 4.3e-249 825.8 0.0 2.8e-87 292.8 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EGD94708.1 - 2.2e-143 476.5 0.0 1.3e-36 126.0 0.0 5.4 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.20 EGD94708.1 - 2e-55 184.8 20.5 1.1e-09 38.3 0.2 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD94708.1 - 3.4e-22 79.1 0.0 3.3e-07 31.1 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EGD94708.1 - 8.1e-06 26.0 0.5 0.022 15.0 0.0 3.0 2 0 0 2 2 2 2 HxxPF-repeated domain WES_acyltransf PF03007.11 EGD94708.1 - 0.0082 15.7 0.0 17 4.8 0.0 3.7 3 0 0 3 3 3 1 Wax ester synthase-like Acyl-CoA acyltransferase domain K_oxygenase PF13434.1 EGD94709.1 - 5.5e-110 367.4 0.0 6.7e-110 367.2 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGD94709.1 - 2.8e-10 40.1 0.0 5.5e-09 35.9 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EGD94709.1 - 2.4e-09 37.5 0.0 6.2e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD94709.1 - 7.1e-07 29.3 0.0 3.5e-05 23.7 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.2 EGD94711.1 - 4.3e-40 135.9 0.0 1.3e-18 67.1 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 EGD94711.1 - 6.4e-38 129.8 8.0 6.4e-38 129.8 5.5 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.25 EGD94711.1 - 8.6e-33 110.5 0.7 5.3e-10 38.6 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EGD94711.1 - 1.8e-24 85.1 0.6 3.7e-07 30.1 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGD94711.1 - 1.3e-23 82.9 3.3 3.5e-08 33.7 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD94711.1 - 1.6e-22 77.2 2.4 2e-08 33.6 0.0 6.3 7 0 0 7 7 7 4 Ankyrin repeat FCP1_C PF09309.5 EGD94711.1 - 0.056 12.7 0.1 0.087 12.1 0.1 1.2 1 0 0 1 1 1 0 FCP1, C-terminal PWI PF01480.12 EGD94712.1 - 2.9e-05 24.0 0.0 6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 PWI domain OB_NTP_bind PF07717.11 EGD94713.1 - 6.9e-30 103.2 0.0 1.7e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGD94713.1 - 5.3e-26 90.6 0.0 5.4e-25 87.3 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGD94713.1 - 7.9e-13 48.0 0.0 1.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cyt-b5 PF00173.23 EGD94714.1 - 3.7e-18 65.0 0.1 4.2e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4291 PF14124.1 EGD94715.1 - 8.1e-76 253.6 0.1 9.1e-76 253.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Mcp5_PH PF12814.2 EGD94716.1 - 5.3e-49 165.2 0.6 1.1e-48 164.2 0.0 1.8 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3584 PF12128.3 EGD94716.1 - 0.073 10.3 12.1 0.1 9.9 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 EGD94716.1 - 5.5 6.7 15.2 2.5 7.8 4.8 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein AMP-binding PF00501.23 EGD94717.1 - 4.6e-77 259.1 0.0 5.5e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD94717.1 - 2.6e-15 57.1 0.1 9.9e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ras PF00071.17 EGD94719.1 - 4.2e-50 169.2 0.5 8.4e-49 165.0 0.3 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGD94719.1 - 1.4e-16 61.1 0.1 8.3e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGD94719.1 - 0.00018 20.8 0.0 0.0014 17.8 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGD94719.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGD94719.1 - 0.048 12.7 0.1 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 EGD94719.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EGD94719.1 - 0.15 11.3 0.2 2 7.6 0.0 2.3 2 1 1 3 3 3 0 Ferrous iron transport protein B Septin PF00735.13 EGD94719.1 - 0.16 10.9 0.7 0.24 10.3 0.0 1.6 2 0 0 2 2 2 0 Septin MFS_1 PF07690.11 EGD94720.1 - 3.1e-35 121.5 33.7 4.2e-35 121.0 23.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FlgH PF02107.11 EGD94722.1 - 0.044 13.3 0.3 0.048 13.2 0.2 1.1 1 0 0 1 1 1 0 Flagellar L-ring protein SHMT PF00464.14 EGD94723.1 - 3.7e-196 651.2 0.0 4.3e-196 651.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EGD94723.1 - 0.034 13.2 0.0 0.063 12.4 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Mor PF08765.6 EGD94723.1 - 0.043 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Mor transcription activator family MOSC PF03473.12 EGD94724.1 - 1.4e-15 56.8 0.0 2.2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EGD94724.1 - 2.5e-13 49.7 0.0 7.8e-13 48.1 0.0 1.8 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF2235 PF09994.4 EGD94725.1 - 5.5e-90 301.4 0.0 6.9e-90 301.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Patatin PF01734.17 EGD94726.1 - 3.1e-28 99.0 0.0 1.1e-27 97.3 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase Mg_trans_NIPA PF05653.9 EGD94727.1 - 6.7e-84 281.3 19.3 9.3e-84 280.9 13.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EGD94727.1 - 1.3e-06 28.6 3.7 1.3e-06 28.6 2.5 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EGD94727.1 - 1e-05 25.5 6.1 1e-05 25.5 4.2 3.2 3 1 1 4 4 4 1 EamA-like transporter family DUF1282 PF06930.7 EGD94727.1 - 8.4 6.0 23.5 0.39 10.3 10.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) PTCB-BRCT PF12738.2 EGD94728.1 - 0.00013 21.6 0.1 0.0004 20.1 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EGD94728.1 - 0.0014 18.7 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DivIC PF04977.10 EGD94729.1 - 0.29 10.6 2.9 0.53 9.8 2.0 1.4 1 0 0 1 1 1 0 Septum formation initiator KilA-N PF04383.8 EGD94730.1 - 0.00049 19.7 0.0 0.0061 16.1 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Gag_spuma PF03276.9 EGD94733.1 - 1.8 6.7 6.2 2.2 6.4 4.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein HA2 PF04408.18 EGD94734.1 - 8.8e-20 70.6 0.0 2.1e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGD94734.1 - 1.1e-11 44.3 0.1 2.6e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD94734.1 - 9.2e-10 38.2 0.0 1.8e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGD94734.1 - 1e-08 35.3 0.1 2.8e-07 30.7 0.1 2.8 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EGD94734.1 - 0.0021 17.0 0.0 0.0042 16.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 EGD94734.1 - 0.0027 18.0 0.6 0.0095 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EGD94734.1 - 0.0028 17.1 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 EGD94734.1 - 0.0056 16.1 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EGD94734.1 - 0.084 13.1 1.5 0.27 11.5 0.1 2.5 2 1 1 3 3 3 0 ABC transporter DUF3554 PF12074.3 EGD94735.1 - 4.8e-69 233.3 4.6 1.6e-68 231.6 1.3 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3554) HEAT PF02985.17 EGD94735.1 - 8.7e-35 115.6 35.8 0.051 13.6 0.0 22.6 24 0 0 24 24 24 9 HEAT repeat HEAT_2 PF13646.1 EGD94735.1 - 1.9e-30 104.9 46.5 1.6e-10 41.1 0.0 14.9 8 3 6 14 14 14 7 HEAT repeats HEAT_EZ PF13513.1 EGD94735.1 - 3.8e-22 78.1 56.4 6.6e-06 26.4 0.0 22.6 21 7 9 30 30 30 6 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGD94735.1 - 1.1e-13 51.3 0.1 0.11 12.8 0.0 8.3 6 1 2 8 8 8 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EGD94735.1 - 3.4e-09 36.8 2.0 0.29 10.9 0.0 8.3 8 1 1 10 10 10 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EGD94735.1 - 8e-08 31.9 0.1 2.3 7.5 0.0 7.1 5 1 3 8 8 8 4 CLASP N terminal ParcG PF10274.4 EGD94735.1 - 2.1e-07 31.0 7.3 0.15 11.9 0.0 6.8 6 1 1 7 7 7 2 Parkin co-regulated protein Ribosomal_L19e PF01280.15 EGD94736.1 - 2e-61 206.0 8.7 2e-61 206.0 6.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 EGD94736.1 - 0.025 13.7 0.8 0.028 13.6 0.6 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF4239 PF14023.1 EGD94736.1 - 0.034 13.5 1.6 0.049 12.9 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) S4 PF01479.20 EGD94736.1 - 0.25 10.8 1.4 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 S4 domain HTH_17 PF12728.2 EGD94736.1 - 0.53 10.5 2.8 14 6.0 0.1 3.2 2 1 1 3 3 3 0 Helix-turn-helix domain Zn_clus PF00172.13 EGD94742.1 - 1.3e-09 37.7 11.0 2.2e-09 37.0 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 EGD94742.1 - 0.88 9.1 4.5 1.8 8.1 3.2 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 adh_short PF00106.20 EGD94744.1 - 2.2e-23 83.0 2.9 1.7e-22 80.0 2.8 2.0 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGD94744.1 - 1.3e-10 41.2 3.5 2.3e-08 33.9 3.3 2.8 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 EGD94744.1 - 6e-10 39.3 0.0 8.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGD94744.1 - 3.5e-06 27.1 0.1 8.7e-06 25.8 0.1 1.9 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGD94744.1 - 0.0039 16.6 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGD94744.1 - 0.0059 15.5 0.0 0.0092 14.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain UPF0146 PF03686.8 EGD94744.1 - 0.038 13.7 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) 3Beta_HSD PF01073.14 EGD94744.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Herpes_U30 PF04523.8 EGD94745.1 - 1.6 6.1 0.2 3 5.1 0.2 1.4 1 0 0 1 1 1 0 Herpes virus tegument protein U30 CorA PF01544.13 EGD94746.1 - 5.6e-41 140.4 1.7 1.7e-40 138.9 1.2 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Vac7 PF12751.2 EGD94747.1 - 1.4e-147 491.6 3.3 1.4e-147 491.6 2.3 2.3 2 1 0 2 2 2 1 Vacuolar segregation subunit 7 RNA_pol_Rpc4 PF05132.9 EGD94747.1 - 0.49 10.3 8.5 0.14 12.1 3.3 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF3824 PF12868.2 EGD94750.1 - 0.00079 20.3 31.4 0.00079 20.3 21.8 10.9 2 1 9 11 11 11 2 Domain of unknwon function (DUF3824) DUF4366 PF14283.1 EGD94750.1 - 0.017 14.5 3.3 0.17 11.2 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) DUF2613 PF11021.3 EGD94750.1 - 0.055 13.1 0.2 0.29 10.8 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF4473 PF14747.1 EGD94750.1 - 1.1 9.5 5.3 3.3 7.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) LMBR1 PF04791.11 EGD94750.1 - 2.2 6.7 5.0 4.7 5.6 3.5 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein Amidohydro_1 PF01979.15 EGD94751.1 - 9.6e-11 41.9 2.9 3.3e-10 40.1 2.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGD94751.1 - 4.5e-08 32.7 0.1 2.3e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EGD94751.1 - 5.2e-08 32.5 3.4 9e-08 31.7 0.4 2.1 1 1 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGD94751.1 - 2e-05 24.7 3.2 0.00014 21.9 2.2 2.2 1 1 0 1 1 1 1 Amidohydrolase Abhydrolase_6 PF12697.2 EGD94753.1 - 5.3e-36 124.6 0.1 6e-36 124.4 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD94753.1 - 3.8e-19 68.8 0.0 3.2e-18 65.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD94753.1 - 7.3e-17 61.7 0.0 5.5e-16 58.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGD94753.1 - 6e-07 29.2 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EGD94753.1 - 1.7e-05 23.4 0.0 2.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.15 EGD94753.1 - 0.0004 20.6 0.0 0.00047 20.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EGD94753.1 - 0.00072 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein PetM PF08041.6 EGD94753.1 - 0.22 11.0 0.6 0.47 9.9 0.4 1.6 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 Fungal_trans PF04082.13 EGD94754.1 - 1.4e-18 66.7 0.3 3.4e-18 65.4 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD94754.1 - 5e-08 32.7 5.3 9.1e-08 31.8 3.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2_5_RNA_ligase2 PF13563.1 EGD94754.1 - 0.026 14.2 0.3 0.05 13.3 0.2 1.4 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Spore_YpjB PF09577.5 EGD94754.1 - 0.03 13.8 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Dickkopf_N PF04706.7 EGD94754.1 - 1.5 8.9 5.9 3.9 7.7 4.1 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Ribosomal_L44 PF00935.14 EGD94755.1 - 1.5e-34 117.7 11.8 2.3e-34 117.2 8.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 ubiquitin PF00240.18 EGD94756.1 - 2.6e-23 81.1 0.0 2.9e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGD94756.1 - 1.1e-14 53.8 0.0 1.2e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGD94756.1 - 7e-05 22.9 0.0 0.00022 21.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Ferritin_2 PF13668.1 EGD94757.1 - 1.7e-18 66.8 0.1 2.6e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain PilN PF05137.8 EGD94757.1 - 0.022 14.5 0.1 0.88 9.4 0.0 2.3 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) Rav1p_C PF12234.3 EGD94758.1 - 2e-271 901.7 0.0 2.5e-271 901.3 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EGD94758.1 - 0.0035 17.1 12.8 0.18 11.7 0.2 5.1 7 0 0 7 7 7 2 WD domain, G-beta repeat OPT PF03169.10 EGD94759.1 - 8.1e-159 529.9 20.0 9.4e-159 529.7 13.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 EGD94759.1 - 0.025 14.5 9.7 0.79 9.7 0.2 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) SH3_9 PF14604.1 EGD94760.1 - 7.7e-08 31.8 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGD94760.1 - 4.3e-06 26.0 0.0 6.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGD94760.1 - 1.7e-05 24.2 0.0 2.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain IncA PF04156.9 EGD94760.1 - 0.31 10.6 0.1 0.53 9.8 0.1 1.3 1 0 0 1 1 1 0 IncA protein Pkinase PF00069.20 EGD94762.1 - 1.9e-38 132.0 0.0 2.7e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94762.1 - 2.1e-13 49.9 0.0 3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD94762.1 - 0.00065 19.5 0.1 0.0074 16.0 0.0 2.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EGD94762.1 - 0.028 13.3 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PA28_alpha PF02251.13 EGD94762.1 - 0.12 12.5 0.1 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Kdo PF06293.9 EGD94762.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGD94762.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL muHD PF10291.4 EGD94763.1 - 2e-69 233.6 0.0 2.9e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EGD94763.1 - 2.2e-10 40.6 0.0 1e-09 38.4 0.0 2.1 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Laminin_II PF06009.7 EGD94763.1 - 0.012 15.4 2.3 0.046 13.4 1.6 2.1 1 0 0 1 1 1 0 Laminin Domain II Spc7 PF08317.6 EGD94763.1 - 0.08 11.5 4.5 0.14 10.7 3.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Muted PF14942.1 EGD94763.1 - 0.085 12.7 2.1 0.19 11.5 1.4 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DivIVA PF05103.8 EGD94763.1 - 2.2 8.3 7.9 0.23 11.5 1.8 2.2 2 1 0 2 2 2 0 DivIVA protein Peptidase_M20 PF01546.23 EGD94764.1 - 5.2e-27 94.5 0.0 9.4e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGD94764.1 - 3.3e-18 65.4 0.1 2.1e-17 62.8 0.1 2.2 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EGD94764.1 - 0.1 12.3 0.0 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M28 MAD PF05557.8 EGD94765.1 - 2.1e-51 174.9 82.0 3.2e-41 141.2 57.0 2.5 2 1 0 2 2 2 2 Mitotic checkpoint protein Bacillus_HBL PF05791.6 EGD94765.1 - 0.0026 17.1 6.3 0.0026 17.1 4.3 6.1 4 3 2 7 7 7 1 Bacillus haemolytic enterotoxin (HBL) Mto2_bdg PF12808.2 EGD94765.1 - 0.005 16.9 4.6 0.005 16.9 3.2 8.2 8 3 3 11 11 11 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Arginosuc_synth PF00764.14 EGD94766.1 - 2.6e-141 471.1 0.0 3.1e-141 470.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EGD94766.1 - 5.2e-06 26.1 0.0 7.2e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EGD94766.1 - 0.0029 16.9 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EGD94766.1 - 0.025 13.1 0.0 0.037 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase DNA_pol3_gamma3 PF12169.3 EGD94766.1 - 0.13 12.0 0.2 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III RNase_H2-Ydr279 PF09468.5 EGD94767.1 - 5 6.2 7.8 5.9 6.0 5.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RasGEF PF00617.14 EGD94768.1 - 9.8e-43 146.0 0.2 1.5e-42 145.4 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGD94768.1 - 8e-14 51.6 0.1 1.8e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Ank_2 PF12796.2 EGD94769.1 - 4.1e-18 65.4 0.3 3.2e-17 62.6 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGD94769.1 - 5.2e-15 54.4 0.0 1.1e-05 24.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGD94769.1 - 1.5e-11 44.0 0.0 7e-06 26.1 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DIL PF01843.14 EGD94769.1 - 6.8e-10 38.7 0.8 6.8e-10 38.7 0.6 2.1 2 1 0 2 2 2 1 DIL domain Ank_4 PF13637.1 EGD94769.1 - 1.4e-09 38.1 0.4 0.013 15.9 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD94769.1 - 2.5e-07 30.2 2.5 0.015 15.4 0.0 4.7 4 1 0 4 4 4 2 Ankyrin repeat BTB PF00651.26 EGD94771.1 - 1.7e-17 63.3 0.1 2.4e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 BTB/POZ domain SKG6 PF08693.5 EGD94772.1 - 6.2e-05 22.2 0.5 0.00012 21.2 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RabGAP-TBC PF00566.13 EGD94773.1 - 2.5e-34 118.6 0.0 4.6e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TPP_enzyme_N PF02776.13 EGD94774.1 - 3.3e-42 143.8 0.0 6.2e-42 142.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGD94774.1 - 9.8e-18 64.1 0.0 3.8e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGD94774.1 - 6.1e-16 58.4 0.0 1.3e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.1 EGD94774.1 - 0.13 11.2 0.0 0.69 8.7 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Mo25 PF08569.6 EGD94775.1 - 3.6e-125 417.4 0.0 4.2e-125 417.2 0.0 1.0 1 0 0 1 1 1 1 Mo25-like Methyltransf_31 PF13847.1 EGD94776.1 - 5.5e-11 42.2 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGD94776.1 - 5.4e-09 35.6 0.0 9e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EGD94776.1 - 3.2e-08 34.1 0.1 9.3e-08 32.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD94776.1 - 7e-08 32.8 0.0 1.6e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD94776.1 - 2.7e-06 27.4 0.0 4.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD94776.1 - 9e-06 25.1 0.1 1.6e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EGD94776.1 - 5e-05 23.0 0.0 9.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGD94776.1 - 0.0009 18.0 0.0 0.0013 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EGD94776.1 - 0.0014 18.9 0.0 0.0035 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EGD94776.1 - 0.0031 16.5 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.7 EGD94776.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EGD94776.1 - 0.031 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 EGD94776.1 - 0.036 13.5 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 EGD94776.1 - 0.039 13.5 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.15 EGD94776.1 - 0.04 12.9 0.1 0.2 10.7 0.0 2.1 3 0 0 3 3 3 0 Mycolic acid cyclopropane synthetase TehB PF03848.9 EGD94776.1 - 0.047 12.8 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 EGD94776.1 - 0.073 13.9 0.0 0.25 12.1 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Cir_N PF10197.4 EGD94777.1 - 0.0015 18.5 7.4 0.0015 18.5 5.1 4.7 5 1 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.24 EGD94778.1 - 7.6e-27 94.1 0.0 3.8e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EGD94778.1 - 3.3e-13 49.3 0.0 7.4e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EGD94778.1 - 8e-11 41.4 0.1 2.2e-09 36.8 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EGD94778.1 - 0.00016 21.5 0.0 0.0046 16.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGD94778.1 - 0.00044 19.9 0.2 0.0041 16.8 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 EGD94778.1 - 0.003 16.6 0.0 0.0071 15.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EGD94778.1 - 0.0035 16.1 0.0 0.0058 15.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EGD94778.1 - 0.0041 16.9 0.0 0.0098 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD94778.1 - 0.0049 17.6 0.0 0.016 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD94778.1 - 0.0089 16.0 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EGD94778.1 - 0.0099 15.5 0.2 0.027 14.1 0.0 1.8 2 0 0 2 2 1 1 NACHT domain AAA_22 PF13401.1 EGD94778.1 - 0.014 15.5 0.0 0.087 12.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGD94778.1 - 0.021 14.9 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EGD94778.1 - 0.028 14.1 0.0 0.078 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EGD94778.1 - 0.037 13.1 0.0 0.076 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EGD94778.1 - 0.038 13.3 0.0 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGD94778.1 - 0.054 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EGD94778.1 - 0.069 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGD94778.1 - 0.076 11.8 0.0 0.2 10.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain KxDL PF10241.4 EGD94780.1 - 5.3e-27 93.5 0.3 6.7e-27 93.2 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein HATPase_c PF02518.21 EGD94781.1 - 3.3e-21 75.0 0.6 6.5e-21 74.1 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGD94781.1 - 6.9e-19 67.9 0.1 1.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EGD94781.1 - 1.8e-16 59.9 0.0 5.8e-16 58.2 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EGD94781.1 - 3.2e-11 43.1 1.2 0.0018 18.3 0.1 3.9 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 EGD94781.1 - 6e-10 39.4 0.1 3.4e-06 27.3 0.0 4.0 3 1 0 3 3 3 1 PAS domain PAS_4 PF08448.5 EGD94781.1 - 7.9e-06 25.8 0.2 3.3e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 EGD94781.1 - 0.0019 17.9 3.4 0.23 11.2 0.0 3.7 4 0 0 4 4 4 1 PAS fold HATPase_c_2 PF13581.1 EGD94781.1 - 0.095 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain OmpH PF03938.9 EGD94781.1 - 1.4 8.8 18.3 6.2 6.7 9.8 2.9 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) F-protein PF00469.15 EGD94781.1 - 3.4 6.9 8.5 7.6 5.8 5.9 1.6 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef HATPase_c PF02518.21 EGD94782.1 - 1.5e-29 101.9 0.0 8.1e-29 99.5 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGD94782.1 - 2.5e-20 72.2 0.0 8.6e-20 70.5 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EGD94782.1 - 5.9e-20 71.3 0.1 1.9e-19 69.7 0.1 2.0 1 0 0 1 1 1 1 Response regulator receiver domain AAA_16 PF13191.1 EGD94782.1 - 3.8e-11 43.3 0.3 5.6e-10 39.5 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain GAF_2 PF13185.1 EGD94782.1 - 2.6e-10 40.9 0.0 7.6e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EGD94782.1 - 5.8e-08 33.0 0.0 1.7e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EGD94782.1 - 3e-07 29.8 0.0 1.4e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.1 EGD94782.1 - 6.3e-07 29.5 0.0 2e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.1 EGD94782.1 - 9.5e-06 25.3 0.2 2.8e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.1 EGD94782.1 - 0.0028 17.7 0.0 0.12 12.5 0.0 3.2 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EGD94782.1 - 0.0034 16.1 0.0 0.0068 15.2 0.0 1.4 1 0 0 1 1 1 1 ArgK protein NB-ARC PF00931.17 EGD94782.1 - 0.0034 16.2 0.0 0.14 11.0 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain AAA_35 PF14516.1 EGD94782.1 - 0.018 13.6 0.0 0.24 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain TPR_2 PF07719.12 EGD94782.1 - 0.049 13.5 2.9 6.1 7.0 0.1 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGD94782.1 - 0.11 12.1 1.5 0.52 9.9 0.2 2.7 2 0 0 2 2 2 0 TPR repeat Allantoicase PF03561.10 EGD94783.1 - 7e-89 295.0 0.0 1.8e-46 157.3 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Cytochrom_B561 PF03188.11 EGD94784.1 - 3.6e-16 59.2 1.8 3.6e-16 59.2 1.3 1.5 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4271 PF14093.1 EGD94784.1 - 0.0043 16.7 4.7 0.0043 16.7 3.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4271) Cytochrom_B_N PF00033.14 EGD94784.1 - 0.027 13.8 6.7 0.098 12.0 3.4 2.4 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 EGD94784.1 - 0.045 13.1 7.1 0.58 9.5 4.9 2.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PepSY_TM_1 PF13172.1 EGD94784.1 - 0.18 11.6 3.2 0.52 10.1 0.1 2.8 2 0 0 2 2 2 0 PepSY-associated TM helix DUF2306 PF10067.4 EGD94784.1 - 0.26 11.4 11.4 0.1 12.6 0.5 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) DUF1129 PF06570.6 EGD94784.1 - 0.35 10.1 4.5 0.67 9.2 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Bax1-I PF01027.15 EGD94784.1 - 1 8.8 13.2 7.1 6.1 9.0 2.0 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 PepSY_TM_2 PF13703.1 EGD94784.1 - 4.2 7.6 9.3 6.3 7.0 0.2 3.8 2 1 1 3 3 3 0 PepSY-associated TM helix DUF2427 PF10348.4 EGD94784.1 - 4.3 6.9 8.0 2.2 7.9 0.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) tRNA-synt_2b PF00587.20 EGD94785.1 - 2.2e-21 76.1 0.0 3.9e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGD94785.1 - 2.7e-08 33.7 3.2 5.7e-08 32.7 2.2 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 EGD94785.1 - 0.00096 17.6 5.1 0.0014 17.1 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DUF2205 PF10224.4 EGD94785.1 - 0.018 14.5 7.1 0.63 9.6 0.1 2.4 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) tRNA-synt_His PF13393.1 EGD94785.1 - 0.019 14.0 1.8 1.4 7.8 1.2 2.2 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Spc7 PF08317.6 EGD94785.1 - 0.023 13.3 2.5 0.036 12.7 1.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EGD94785.1 - 0.041 13.4 0.9 0.062 12.8 0.6 1.2 1 0 0 1 1 1 0 IncA protein Flagellar_rod PF05149.7 EGD94785.1 - 0.087 12.0 2.9 0.13 11.4 2.0 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein CorA PF01544.13 EGD94785.1 - 0.15 11.0 0.7 0.23 10.4 0.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2203 PF09969.4 EGD94785.1 - 0.16 12.2 0.7 0.44 10.7 0.5 1.8 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2203) Mnd1 PF03962.10 EGD94785.1 - 0.17 11.5 4.3 0.29 10.7 3.0 1.3 1 0 0 1 1 1 0 Mnd1 family TMF_DNA_bd PF12329.3 EGD94785.1 - 2 8.2 9.0 6.3 6.6 0.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EGD94785.1 - 7.7 6.0 6.8 3.7 7.0 0.2 2.3 1 1 0 2 2 2 0 Septum formation initiator APH PF01636.18 EGD94786.1 - 8e-09 35.5 0.0 3.7e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EGD94786.1 - 9.1e-06 24.8 0.0 0.0035 16.3 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase DUF1679 PF07914.6 EGD94786.1 - 0.001 17.8 0.0 0.0019 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EGD94786.1 - 0.066 12.3 0.0 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase ABC_membrane PF00664.18 EGD94788.1 - 2.8e-75 253.2 39.6 1.6e-39 135.9 13.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD94788.1 - 1.2e-68 229.6 0.1 5.6e-34 117.3 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EGD94788.1 - 7.7e-13 49.0 0.8 0.0045 16.9 0.0 4.7 5 0 0 5 5 5 3 AAA domain DUF258 PF03193.11 EGD94788.1 - 1.2e-09 37.5 0.0 0.00016 20.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGD94788.1 - 1.2e-09 37.4 0.4 0.00034 20.0 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EGD94788.1 - 2.9e-08 32.7 3.0 0.00096 17.8 0.0 4.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EGD94788.1 - 4.1e-08 33.4 1.6 0.0029 17.6 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EGD94788.1 - 6.1e-08 33.5 0.0 0.0043 17.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.14 EGD94788.1 - 2.5e-07 30.1 3.2 0.015 14.5 0.1 4.3 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EGD94788.1 - 5.8e-07 29.7 0.9 0.15 12.1 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGD94788.1 - 6.1e-06 25.7 0.0 0.083 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGD94788.1 - 2.6e-05 23.9 0.1 0.025 14.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGD94788.1 - 8.2e-05 22.5 0.1 0.15 11.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 EGD94788.1 - 0.00016 21.9 0.9 0.34 11.1 0.0 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EGD94788.1 - 0.0002 21.2 0.0 0.07 13.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 EGD94788.1 - 0.00031 20.4 0.0 0.14 11.8 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EGD94788.1 - 0.00048 20.1 0.6 2.1 8.2 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGD94788.1 - 0.0006 19.7 0.0 0.45 10.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EGD94788.1 - 0.00098 19.4 0.5 1.1 9.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EGD94788.1 - 0.0033 17.5 0.1 0.19 11.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_10 PF12846.2 EGD94788.1 - 0.0033 16.8 1.1 0.76 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain AAA_23 PF13476.1 EGD94788.1 - 0.013 15.8 6.0 0.93 9.7 0.1 2.9 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EGD94788.1 - 0.024 15.1 0.0 2.5 8.6 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 EGD94788.1 - 0.062 12.3 0.3 13 4.8 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin APS_kinase PF01583.15 EGD94788.1 - 0.094 12.3 0.2 2.5 7.7 0.1 2.8 2 1 0 2 2 2 0 Adenylylsulphate kinase TEX19 PF15553.1 EGD94788.1 - 0.45 10.3 1.9 0.88 9.4 1.3 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF3632 PF12311.3 EGD94789.1 - 1.2e-34 119.7 0.1 1.7e-34 119.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) AMP-binding PF00501.23 EGD94790.1 - 6.9e-28 97.1 0.2 1e-27 96.6 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD94790.1 - 0.0042 18.0 0.0 0.0085 17.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EGD94791.1 - 9.6e-10 37.4 0.0 1.1e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.11 EGD94792.1 - 3e-29 101.8 38.0 3e-29 101.8 26.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGD94792.1 - 0.014 14.9 2.8 0.037 13.5 1.9 1.8 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Gln-synt_C PF00120.19 EGD94793.1 - 1.4e-59 201.3 0.0 1.7e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EGD94793.1 - 2.3e-20 71.9 0.0 3.6e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Med1 PF10744.4 EGD94794.1 - 3.1e-54 184.2 0.1 3.6e-31 108.3 0.0 2.7 3 0 0 3 3 3 2 Mediator of RNA polymerase II transcription subunit 1 Ank_2 PF12796.2 EGD94795.1 - 1.6e-24 86.0 0.0 5e-09 36.3 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EGD94795.1 - 3.7e-20 70.6 0.1 0.00097 18.8 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EGD94795.1 - 1.7e-13 50.6 0.2 0.0045 17.4 0.1 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD94795.1 - 3.7e-11 42.8 1.4 0.0068 16.6 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD94795.1 - 6.6e-09 35.1 1.4 7.4 7.1 0.0 6.8 6 1 0 6 6 6 3 Ankyrin repeat F-box-like PF12937.2 EGD94795.1 - 0.025 14.3 0.2 0.061 13.0 0.2 1.7 1 0 0 1 1 1 0 F-box-like MACPF PF01823.14 EGD94796.1 - 1.2e-16 61.0 2.2 1.9e-16 60.4 1.6 1.2 1 0 0 1 1 1 1 MAC/Perforin domain DUF1344 PF07076.6 EGD94796.1 - 0.056 13.0 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) FecR PF04773.8 EGD94796.1 - 0.37 11.0 2.6 0.56 10.4 0.1 2.5 3 0 0 3 3 3 0 FecR protein zf-MYND PF01753.13 EGD94797.1 - 0.15 11.9 2.7 5.9 6.8 0.1 2.3 2 0 0 2 2 2 0 MYND finger DUF159 PF02586.9 EGD94799.1 - 1.4e-44 152.1 0.0 9.1e-27 93.9 0.0 2.2 1 1 1 2 2 2 2 Uncharacterised ACR, COG2135 TPR_12 PF13424.1 EGD94800.1 - 1.9e-08 34.1 9.4 0.038 13.9 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGD94800.1 - 6.6e-05 22.5 3.9 0.66 10.0 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGD94800.1 - 0.00021 20.7 4.5 0.12 12.0 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGD94800.1 - 0.0023 17.5 8.4 2.3 7.9 0.1 4.1 4 0 0 4 4 4 3 TPR repeat TPR_8 PF13181.1 EGD94800.1 - 0.025 14.3 5.7 9.6 6.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4071 PF13281.1 EGD94800.1 - 0.027 13.3 1.7 2 7.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) TPR_7 PF13176.1 EGD94800.1 - 0.073 12.8 10.3 23 5.1 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.1 EGD94800.1 - 0.096 11.8 7.5 3.7 6.6 1.7 3.1 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 EGD94800.1 - 0.17 12.2 7.0 0.52 10.6 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD94800.1 - 6.2 7.5 12.3 10 6.8 0.0 5.9 5 2 2 7 7 7 0 Tetratricopeptide repeat WD40 PF00400.27 EGD94801.1 - 6.5e-60 197.0 26.9 9.5e-12 44.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGD94801.1 - 0.00018 19.8 8.4 0.48 8.5 0.3 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGD94801.1 - 0.0072 14.6 0.0 0.62 8.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 EGD94801.1 - 0.029 14.0 0.1 41 3.9 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Sdh5 PF03937.11 EGD94802.1 - 4.2e-23 80.8 1.4 4.3e-23 80.7 0.1 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase EMP24_GP25L PF01105.19 EGD94803.1 - 2.7e-41 141.2 0.0 3.3e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MAD PF05557.8 EGD94803.1 - 0.07 11.2 0.2 0.091 10.8 0.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Dicty_REP PF05086.7 EGD94805.1 - 0.8 7.3 12.0 1.5 6.4 8.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 EGD94805.1 - 1.8 8.3 10.6 0.9 9.3 4.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) FAM176 PF14851.1 EGD94807.1 - 0.00049 19.7 0.5 0.0023 17.5 0.1 2.2 2 0 0 2 2 2 1 FAM176 family TRAP_alpha PF03896.11 EGD94807.1 - 0.17 10.8 4.0 0.31 9.9 2.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.7 EGD94807.1 - 0.35 10.1 13.9 0.5 9.5 9.6 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EGD94807.1 - 2.8 5.7 15.8 3.9 5.2 10.9 1.3 1 0 0 1 1 1 0 Nop14-like family UBN_AB PF14075.1 EGD94809.1 - 0.024 14.2 0.7 0.034 13.8 0.4 1.3 1 1 0 1 1 1 0 Ubinuclein conserved middle domain Neur_chan_memb PF02932.11 EGD94810.1 - 2.8 7.7 12.3 2.9 7.7 1.7 2.6 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region NDUFA12 PF05071.11 EGD94811.1 - 3.4e-13 49.9 0.9 3.4e-13 49.9 0.6 2.2 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF2076 PF09849.4 EGD94811.1 - 2.2 8.2 8.5 2.8 7.9 5.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CH PF00307.26 EGD94812.1 - 1e-10 41.5 0.0 1.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 EGD94812.1 - 0.07 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin PGA2 PF07543.7 EGD94813.1 - 0.28 10.9 6.3 1.3 8.8 3.2 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 ORMDL PF04061.9 EGD94816.1 - 2.1e-61 205.4 4.1 2.4e-61 205.2 2.9 1.0 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 EGD94816.1 - 0.46 10.1 4.6 0.41 10.2 0.9 1.9 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) zf-ribbon_3 PF13248.1 EGD94818.1 - 0.18 11.0 6.3 0.17 11.1 2.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain VESA1_N PF12785.2 EGD94818.1 - 0.43 9.4 12.4 0.72 8.7 8.6 1.3 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 zf-CCHC_2 PF13696.1 EGD94818.1 - 8.6 5.9 12.6 4 7.0 0.3 3.1 3 0 0 3 3 3 0 Zinc knuckle HAD_2 PF13419.1 EGD94819.1 - 3.5e-12 46.8 0.1 1.3e-11 45.0 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGD94819.1 - 1.3e-10 42.0 0.0 1.2e-06 29.1 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD94819.1 - 1.2e-08 34.5 0.1 1.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EGD94819.1 - 1.3e-05 25.4 0.0 2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EGD94819.1 - 0.024 14.5 0.1 0.18 11.6 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase APH PF01636.18 EGD94820.1 - 3.7e-11 43.2 0.0 8.7e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD94820.1 - 0.033 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 EGD94820.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.6 EGD94820.1 - 0.097 11.2 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) TRP PF06011.7 EGD94824.1 - 5.1e-103 344.9 22.1 3.6e-62 210.3 5.2 2.1 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGD94824.1 - 4.7e-34 117.4 0.1 7.7e-34 116.7 0.1 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 EGD94824.1 - 0.064 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 ML domain IncA PF04156.9 EGD94824.1 - 0.18 11.4 2.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 IncA protein Phage_holin_1 PF04531.8 EGD94824.1 - 8.1 6.5 7.6 0.71 9.9 0.0 3.0 2 1 1 3 3 3 0 Bacteriophage holin zf-U1 PF06220.7 EGD94825.1 - 4.9e-06 25.9 0.8 6.9e-06 25.5 0.6 1.2 1 0 0 1 1 1 1 U1 zinc finger p450 PF00067.17 EGD94826.1 - 1.7e-58 198.3 0.0 2.1e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HsbA PF12296.3 EGD94827.1 - 1.2e-14 54.2 0.0 1.8e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF3602 PF12223.3 EGD94829.1 - 5.1e-17 62.0 1.0 1.7e-10 41.0 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 EGD94829.1 - 0.57 9.8 3.5 20 4.7 0.1 3.0 1 1 1 3 3 3 0 GTP1/OBG Actin PF00022.14 EGD94830.1 - 3.5e-86 289.0 0.0 3e-59 200.4 0.0 2.0 1 1 1 2 2 2 2 Actin Glyco_tran_28_C PF04101.11 EGD94831.1 - 1.6e-18 66.9 0.0 4.5e-18 65.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EGD94831.1 - 0.008 15.4 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 MRP-S28 PF10213.4 EGD94832.1 - 8e-10 38.8 0.1 1.4e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein TMEM206 PF15122.1 EGD94834.1 - 0.06 12.2 0.1 0.082 11.8 0.1 1.1 1 0 0 1 1 1 0 TMEM206 protein family Glyco_hydro_3 PF00933.16 EGD94836.1 - 4.9e-95 317.9 0.0 8.3e-95 317.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGD94836.1 - 3e-53 180.6 0.8 3.2e-52 177.3 0.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGD94836.1 - 2.8e-11 43.2 0.0 5.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_47 PF01532.15 EGD94837.1 - 4.5e-156 520.0 0.0 5e-86 289.1 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EGD94837.1 - 0.0007 17.9 0.0 0.062 11.5 0.0 2.4 2 1 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) SKG6 PF08693.5 EGD94838.1 - 0.0015 17.8 0.0 0.0034 16.6 0.0 1.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Sensor PF13796.1 EGD94838.1 - 0.011 15.3 0.1 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Putative sensor DUF4622 PF15415.1 EGD94838.1 - 0.041 12.6 0.0 0.058 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4622) Fungal_trans PF04082.13 EGD94839.1 - 1.1e-24 86.7 0.0 2.9e-24 85.3 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD94839.1 - 5.4e-09 35.8 10.8 9.6e-09 35.0 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CIMR PF00878.13 EGD94840.1 - 6.9e-08 32.3 0.1 0.0002 21.1 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 EGD94840.1 - 6e-07 28.7 0.0 9.4e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 EGD94840.1 - 0.12 11.5 0.0 0.12 11.5 0.0 2.5 1 1 1 2 2 2 0 Autophagy-related protein 27 CDC45 PF02724.9 EGD94840.1 - 0.25 9.3 2.8 0.35 8.8 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein ERG4_ERG24 PF01222.12 EGD94841.1 - 2.9e-138 461.0 0.1 1.9e-137 458.3 0.1 1.8 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGD94841.1 - 0.00019 20.8 0.4 0.00043 19.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) A_deamin PF02137.13 EGD94842.1 - 1.3e-46 159.4 0.0 1.7e-45 155.8 0.0 2.0 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain APOBEC_N PF08210.6 EGD94842.1 - 0.0082 15.7 0.0 0.045 13.3 0.0 2.1 2 1 0 2 2 2 1 APOBEC-like N-terminal domain SF3b10 PF07189.6 EGD94844.1 - 1.5e-34 117.6 0.0 1.7e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) p450 PF00067.17 EGD94847.1 - 6.1e-41 140.4 0.0 9.3e-38 129.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 TAXi_C PF14541.1 EGD94847.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal p450 PF00067.17 EGD94848.1 - 7.6e-30 103.8 0.0 1.2e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NT-C2 PF10358.4 EGD94849.1 - 1.8e-11 43.7 0.0 2.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SLS PF14611.1 EGD94850.1 - 2.9e-53 180.3 0.0 4.6e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Myotub-related PF06602.9 EGD94851.1 - 7.2e-124 413.1 0.0 9.3e-124 412.7 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EGD94851.1 - 0.0001 22.5 0.3 0.0025 18.0 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGD94851.1 - 0.027 13.7 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_S3_C PF00189.15 EGD94852.1 - 1.1e-16 60.7 0.0 2.3e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EGD94852.1 - 2.6e-12 46.1 0.1 4.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EGD94852.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 B3_4 PF03483.12 EGD94853.1 - 1.1e-24 86.7 0.1 2.2e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EGD94853.1 - 2.6e-19 68.7 0.0 4e-16 58.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2740 PF10872.3 EGD94853.1 - 0.089 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) HEAT PF02985.17 EGD94854.1 - 2.5e-42 139.1 15.8 0.0028 17.6 0.1 12.0 13 0 0 13 13 13 11 HEAT repeat HEAT_2 PF13646.1 EGD94854.1 - 5.4e-32 109.9 4.6 1.9e-08 34.4 0.0 6.7 2 1 3 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 EGD94854.1 - 1.6e-11 44.2 9.7 0.00089 19.6 0.0 8.7 6 3 4 10 10 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGD94854.1 - 2.5e-10 40.5 2.9 0.00017 21.8 0.1 6.4 5 2 3 8 8 8 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EGD94854.1 - 1.9e-08 33.1 6.0 4.2e-07 28.6 0.8 3.6 2 1 2 4 4 4 2 Adaptin N terminal region Cnd3 PF12719.2 EGD94854.1 - 0.0046 15.9 0.5 0.03 13.3 0.2 2.3 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.3 EGD94854.1 - 0.0062 15.9 2.3 3.2 7.0 0.1 4.5 4 2 2 6 6 6 1 CLASP N terminal DUF2435 PF10363.4 EGD94854.1 - 0.008 16.0 4.3 2.4 8.0 0.2 4.1 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Arm PF00514.18 EGD94854.1 - 0.025 14.4 4.5 2.3 8.1 0.0 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EGD94854.1 - 0.25 11.1 6.1 3.9 7.2 0.1 4.4 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Glyco_transf_8 PF01501.15 EGD94855.1 - 2.3e-35 122.1 0.0 3.8e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Prok-E2_E PF14462.1 EGD94855.1 - 0.083 12.4 0.3 0.77 9.3 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family E Abhydrolase_6 PF12697.2 EGD94856.1 - 1.1e-22 81.0 0.1 2.7e-22 79.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD94856.1 - 9.4e-08 31.8 0.0 1.1e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD94856.1 - 5.7e-06 26.1 0.0 2.9e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 EGD94856.1 - 0.0036 17.1 0.9 0.0079 16.1 0.3 1.9 2 1 0 2 2 2 1 Epoxide hydrolase N terminus CDV3 PF15359.1 EGD94856.1 - 0.024 14.6 0.1 0.054 13.5 0.0 1.5 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Abhydrolase_2 PF02230.11 EGD94856.1 - 0.028 13.8 0.0 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Glyco_transf_90 PF05686.7 EGD94857.1 - 6.6e-16 57.9 10.4 1.4e-12 47.0 5.5 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 90 CDO_I PF05995.7 EGD94858.1 - 2.3e-40 137.6 0.1 2.7e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EGD94858.1 - 4.4e-08 32.7 0.1 5.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) TGS PF02824.16 EGD94859.1 - 2.9e-22 78.2 0.0 6.3e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EGD94859.1 - 1.2e-18 67.1 0.1 2.9e-18 65.9 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGD94859.1 - 2.7e-09 36.5 0.0 1.3e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGD94859.1 - 0.00032 20.5 0.1 0.061 13.1 0.0 2.3 2 0 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EGD94859.1 - 0.0006 19.2 0.1 3.7 6.9 0.0 3.6 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EGD94859.1 - 0.0052 15.5 0.1 0.012 14.4 0.1 1.6 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 EGD94859.1 - 0.03 14.8 0.1 0.085 13.3 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein Arf PF00025.16 EGD94859.1 - 0.11 11.6 0.3 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF3289 PF11692.3 EGD94860.1 - 0.016 14.5 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) SCIMP PF15050.1 EGD94860.1 - 8.1 6.3 8.1 19 5.1 0.1 2.5 2 1 0 2 2 2 0 SCIMP protein PXA PF02194.10 EGD94861.1 - 1.9e-40 138.4 0.3 6.8e-40 136.6 0.0 2.1 2 0 0 2 2 2 1 PXA domain MDFI PF15316.1 EGD94861.1 - 9.3 6.2 7.3 14 5.6 0.6 2.7 2 0 0 2 2 2 0 MyoD family inhibitor IU_nuc_hydro PF01156.14 EGD94862.1 - 4.4e-86 288.9 0.0 5.1e-86 288.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MR_MLE_C PF13378.1 EGD94863.1 - 7.7e-33 112.7 0.0 1.4e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EGD94863.1 - 1e-17 64.2 0.0 2.3e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EGD94863.1 - 1.3e-09 38.3 0.0 3.3e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Vac_ImportDeg PF09783.4 EGD94864.1 - 1.5e-45 154.8 0.6 7e-45 152.6 0.1 2.0 2 0 0 2 2 2 1 Vacuolar import and degradation protein Macoilin PF09726.4 EGD94864.1 - 2.3 6.4 6.0 3.5 5.7 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L7Ae PF01248.21 EGD94865.1 - 4.1e-27 93.5 0.6 5.3e-27 93.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EGD94865.1 - 0.03 13.9 0.1 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ank_2 PF12796.2 EGD94866.1 - 2e-27 95.3 0.3 4.1e-18 65.4 0.2 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD94866.1 - 2.1e-24 85.0 0.6 1.5e-10 40.9 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EGD94866.1 - 4e-22 76.8 0.4 2e-07 30.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EGD94866.1 - 1.9e-16 58.5 0.0 8e-06 25.6 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EGD94866.1 - 8.9e-15 54.7 0.1 5.2e-08 33.1 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Steroid_dh PF02544.11 EGD94867.1 - 1.1e-09 38.1 1.3 1.1e-09 38.1 0.9 2.3 1 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase 2OG-FeII_Oxy_2 PF13532.1 EGD94868.1 - 5.6e-13 49.1 0.0 2.2e-12 47.2 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGD94868.1 - 0.00012 22.2 0.0 0.00028 21.1 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SKG6 PF08693.5 EGD94870.1 - 0.015 14.6 0.5 0.015 14.6 0.3 2.1 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Rotamase_3 PF13616.1 EGD94871.1 - 3.7e-17 62.6 0.1 6e-17 61.9 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EGD94871.1 - 5.2e-16 59.1 0.0 8.4e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EGD94871.1 - 2.6e-05 24.8 0.0 3.7e-05 24.3 0.0 1.2 1 1 0 1 1 1 1 PPIC-type PPIASE domain UAA PF08449.6 EGD94872.1 - 2.6e-70 236.7 11.2 7.6e-70 235.2 7.8 1.6 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EGD94872.1 - 2e-07 30.3 0.2 0.0016 17.5 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 EGD94872.1 - 0.00023 21.1 10.1 0.00023 21.1 7.0 3.8 4 1 0 4 4 4 2 EamA-like transporter family EmrE PF13536.1 EGD94872.1 - 0.0019 18.4 7.3 0.0019 18.4 5.1 2.9 3 1 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EGD94872.1 - 1.1 8.8 23.1 0.22 11.1 7.3 3.1 2 2 0 2 2 2 0 Triose-phosphate Transporter family Sen15 PF09631.5 EGD94873.1 - 3.6e-10 39.9 0.0 1.2e-09 38.2 0.0 1.8 1 1 0 1 1 1 1 Sen15 protein PH PF00169.24 EGD94874.1 - 5.2e-07 29.8 0.0 1.3e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 EGD94874.1 - 0.0004 19.8 0.0 0.00093 18.6 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 EGD94874.1 - 0.0025 18.0 1.2 1.7 8.9 0.0 3.1 3 0 0 3 3 3 2 Pleckstrin homology domain Kri1 PF05178.7 EGD94875.1 - 3.9e-29 100.8 22.6 3.9e-29 100.8 15.6 5.3 5 1 0 5 5 5 1 KRI1-like family Kri1_C PF12936.2 EGD94875.1 - 3.2e-28 97.5 0.3 3.2e-28 97.5 0.2 4.7 3 2 2 5 5 5 1 KRI1-like family C-terminal Mito_carr PF00153.22 EGD94876.1 - 2.5e-67 222.6 5.3 9.8e-24 82.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Stb3 PF10330.4 EGD94878.1 - 8.6e-35 118.3 0.0 1.5e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein APH PF01636.18 EGD94880.1 - 7.6e-17 61.8 0.0 3.5e-16 59.6 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family XkdW PF09636.5 EGD94880.1 - 0.024 14.5 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 0 XkdW protein RIO1 PF01163.17 EGD94880.1 - 0.028 13.7 0.0 0.074 12.4 0.0 1.7 2 0 0 2 2 2 0 RIO1 family PTS_2-RNA PF01885.11 EGD94881.1 - 8.2e-64 214.3 0.0 1e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family zf-rbx1 PF12678.2 EGD94882.1 - 0.005 16.9 5.7 0.017 15.2 3.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger Nucleoporin_N PF08801.6 EGD94882.1 - 0.012 14.4 0.0 0.13 11.0 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like zf-RING_2 PF13639.1 EGD94882.1 - 1.8 8.4 12.0 0.035 13.9 2.1 2.7 2 1 0 2 2 2 0 Ring finger domain DUF2361 PF10153.4 EGD94883.1 - 2.5e-29 101.7 16.9 2.5e-29 101.7 11.7 2.5 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) DUF573 PF04504.9 EGD94883.1 - 0.0078 16.4 1.9 0.0078 16.4 1.3 2.6 2 1 2 4 4 4 1 Protein of unknown function, DUF573 LRR_6 PF13516.1 EGD94884.1 - 9e-12 43.7 20.8 0.012 15.6 0.1 7.9 9 0 0 9 9 9 4 Leucine Rich repeat F-box-like PF12937.2 EGD94884.1 - 2.3e-11 43.2 0.2 5.9e-11 41.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGD94884.1 - 5.6e-11 41.7 10.2 7e-06 25.5 0.7 5.5 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.28 EGD94884.1 - 8.2e-10 38.0 0.4 2.2e-09 36.7 0.3 1.8 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 EGD94884.1 - 5.3e-06 25.7 16.7 0.38 10.9 0.4 7.4 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_8 PF13855.1 EGD94884.1 - 6.9e-06 25.7 12.0 0.032 13.9 0.1 4.9 4 1 1 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 EGD94884.1 - 0.047 13.8 18.5 2.1 8.9 0.3 7.2 8 0 0 8 8 8 0 Leucine rich repeat PRANC PF09372.5 EGD94884.1 - 0.14 12.1 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 PRANC domain Pkinase PF00069.20 EGD94885.1 - 7.7e-58 195.6 0.0 1.2e-57 195.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94885.1 - 4e-20 71.9 0.0 6.8e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD94885.1 - 9.5e-06 24.7 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD94885.1 - 0.00019 21.2 0.1 0.00077 19.2 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGD94885.1 - 0.004 16.5 0.2 0.0093 15.3 0.2 1.5 1 1 0 1 1 1 1 RIO1 family PAS_9 PF13426.1 EGD94885.1 - 0.011 16.0 0.0 1.8 8.9 0.0 3.5 4 0 0 4 4 4 0 PAS domain PAS_8 PF13188.1 EGD94885.1 - 0.018 14.9 0.0 5 7.1 0.0 3.0 3 0 0 3 3 3 0 PAS domain Choline_kinase PF01633.15 EGD94885.1 - 0.073 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RabGAP-TBC PF00566.13 EGD94886.1 - 2.3e-34 118.7 1.6 6.9e-34 117.2 1.1 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RAP1 PF07218.6 EGD94886.1 - 5 5.0 8.3 6.9 4.6 5.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Yippee-Mis18 PF03226.9 EGD94889.1 - 3e-24 84.8 0.8 3.3e-24 84.7 0.5 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.4 EGD94889.1 - 0.0051 16.7 1.7 0.042 13.8 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) HNH_5 PF14279.1 EGD94889.1 - 0.017 15.1 2.5 0.23 11.5 0.1 2.2 1 1 0 2 2 2 0 HNH endonuclease DUF4451 PF14616.1 EGD94889.1 - 0.02 14.6 1.7 0.028 14.1 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Evr1_Alr PF04777.8 EGD94889.1 - 0.029 14.2 2.5 0.36 10.7 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family RIG-I_C-RD PF11648.3 EGD94889.1 - 0.029 14.2 2.7 0.061 13.1 1.8 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I Endonuclease_7 PF02945.10 EGD94889.1 - 0.033 13.8 2.4 0.067 12.9 1.6 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII DiS_P_DiS PF06750.8 EGD94889.1 - 0.1 12.4 0.4 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain DZR PF12773.2 EGD94889.1 - 0.11 12.3 0.7 0.24 11.2 0.5 1.5 1 1 0 1 1 1 0 Double zinc ribbon Elf1 PF05129.8 EGD94889.1 - 0.12 12.0 0.8 2.5 7.8 0.1 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Eapp_C PF10238.4 EGD94889.1 - 0.46 10.3 5.0 0.84 9.5 0.9 2.1 1 1 1 2 2 2 0 E2F-associated phosphoprotein ADH_N PF08240.7 EGD94890.1 - 2.7e-29 101.1 1.0 4.8e-29 100.3 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD94890.1 - 4.1e-21 74.8 0.0 6.4e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EGD94890.1 - 0.022 14.4 0.3 0.067 12.8 0.2 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Dehydratase_hem PF13816.1 EGD94891.1 - 7.6e-118 393.0 0.0 8.8e-118 392.8 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 EGD94891.1 - 1.2e-08 35.0 0.1 0.00076 19.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) KH_1 PF00013.24 EGD94892.1 - 7.4e-39 131.2 9.8 1.7e-15 56.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGD94892.1 - 2.3e-29 100.5 11.1 1.3e-11 43.8 0.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EGD94892.1 - 1.4e-10 40.5 7.4 0.00045 19.7 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGD94892.1 - 6e-09 35.4 3.2 0.054 13.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EGD94892.1 - 0.0011 18.7 4.1 0.89 9.4 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EGD94892.1 - 0.014 14.8 0.3 3.3 7.1 0.0 3.2 3 0 0 3 3 3 0 dUTPase Epimerase PF01370.16 EGD94893.1 - 1.1e-17 64.2 0.0 1.8e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD94893.1 - 9.1e-14 50.8 0.0 1.2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGD94893.1 - 9.9e-10 37.7 0.0 1.6e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGD94893.1 - 3.1e-08 33.8 0.4 1.9e-07 31.3 0.3 2.2 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EGD94893.1 - 6.7e-08 32.6 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD94893.1 - 1e-06 28.5 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGD94893.1 - 0.0013 17.6 0.0 0.0018 17.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EGD94893.1 - 0.014 14.6 0.3 0.057 12.6 0.1 2.0 2 1 0 2 2 2 0 NmrA-like family DSBA PF01323.15 EGD94894.1 - 4.5e-36 124.2 0.0 5e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EGD94894.1 - 0.0038 17.2 0.1 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Pkinase PF00069.20 EGD94895.1 - 1.7e-26 92.9 0.0 2.3e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94895.1 - 4.5e-08 32.4 0.0 6.5e-07 28.6 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase DUF604 PF04646.7 EGD94896.1 - 0.05 12.8 0.1 0.082 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 ABC2_membrane PF01061.19 EGD94897.1 - 1.4e-36 125.6 35.2 2.5e-32 111.7 5.0 4.8 4 1 2 6 6 6 3 ABC-2 type transporter ABC_tran PF00005.22 EGD94897.1 - 2.8e-21 76.2 0.1 7.1e-13 49.0 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EGD94897.1 - 2.2e-16 59.3 0.3 4.2e-12 45.6 0.0 3.2 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EGD94897.1 - 3.9e-07 30.0 0.4 3.3e-06 27.0 0.3 2.4 1 1 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EGD94897.1 - 0.0022 17.0 9.9 0.0022 17.0 6.9 2.3 2 1 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EGD94897.1 - 0.017 14.2 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGD94897.1 - 0.018 15.0 0.1 0.053 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.14 EGD94897.1 - 0.041 13.0 0.0 0.2 10.8 0.0 2.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD94897.1 - 0.045 13.7 0.1 13 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGD94897.1 - 0.083 12.4 0.1 0.65 9.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EGD94897.1 - 0.19 11.6 0.5 0.42 10.4 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGD94897.1 - 0.23 11.7 0.0 0.49 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.9 EGD94901.1 - 0.57 8.1 3.7 0.67 7.9 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGD94901.1 - 1.8 6.3 6.2 2.3 6.0 4.3 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EGD94901.1 - 2.6 7.2 8.0 5 6.2 4.5 1.8 2 0 0 2 2 2 0 NOA36 protein CENP-B_dimeris PF09026.5 EGD94901.1 - 9.8 6.4 13.7 1.4 9.1 5.8 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DSPc PF00782.15 EGD94904.1 - 2.6e-21 75.5 0.0 3.9e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD94904.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Beta-lactamase PF00144.19 EGD94905.1 - 1.1e-46 159.4 0.0 1.5e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EGD94905.1 - 1.5e-07 31.2 0.1 3.1e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) ABC_membrane PF00664.18 EGD94906.1 - 3.8e-82 275.7 39.8 3.6e-46 157.7 12.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD94906.1 - 2.1e-71 238.6 0.0 1.2e-34 119.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGD94906.1 - 4.4e-16 58.7 6.9 3e-05 23.3 0.1 4.5 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD94906.1 - 3.5e-13 50.1 0.5 0.00048 20.1 0.1 4.3 2 2 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EGD94906.1 - 9.1e-09 35.5 0.9 5e-05 23.3 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EGD94906.1 - 1.2e-08 33.9 0.6 0.0016 17.1 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EGD94906.1 - 7e-08 31.8 0.2 0.0095 15.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EGD94906.1 - 1.4e-07 30.7 0.0 0.006 15.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGD94906.1 - 1.3e-06 29.2 0.0 0.0011 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGD94906.1 - 1.7e-05 24.9 0.6 0.068 13.3 0.1 3.6 2 2 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGD94906.1 - 3.6e-05 22.9 0.3 0.34 9.9 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_5 PF07728.9 EGD94906.1 - 8.5e-05 22.2 0.2 0.3 10.8 0.0 3.9 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EGD94906.1 - 0.00014 22.1 1.1 13 5.9 0.1 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGD94906.1 - 0.00017 21.5 0.0 0.088 12.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EGD94906.1 - 0.00017 21.3 2.7 0.73 9.7 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EGD94906.1 - 0.00036 20.8 0.0 0.024 14.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EGD94906.1 - 0.00038 20.0 1.2 0.41 10.2 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.1 EGD94906.1 - 0.0014 18.5 0.1 1.7 8.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 EGD94906.1 - 0.0031 17.8 0.0 4.5 7.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 EGD94906.1 - 0.0035 16.9 0.0 0.54 9.7 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.8 EGD94906.1 - 0.0069 15.3 0.0 1.2 8.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 EGD94906.1 - 0.0071 16.3 1.2 0.74 9.7 0.1 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGD94906.1 - 0.0086 14.8 0.0 0.58 8.7 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_25 PF13481.1 EGD94906.1 - 0.011 15.2 0.1 1.2 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.1 EGD94906.1 - 0.011 14.2 0.0 0.094 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MobB PF03205.9 EGD94906.1 - 0.015 14.9 0.1 0.18 11.4 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EGD94906.1 - 0.023 14.5 0.3 15 5.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_15 PF13175.1 EGD94906.1 - 0.025 13.6 0.1 5.3 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EGD94906.1 - 0.03 14.2 0.1 2.2 8.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EGD94906.1 - 0.041 13.3 3.5 0.87 8.9 0.1 3.1 3 1 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 EGD94906.1 - 0.047 13.8 0.1 6.8 6.9 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 EGD94906.1 - 1.3 8.8 8.2 5.9 6.6 0.3 4.7 5 2 0 5 5 4 0 Dynamin family AMP-binding PF00501.23 EGD94907.1 - 2e-150 500.8 0.0 3.3e-76 256.3 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EGD94907.1 - 7.5e-119 396.0 0.0 1.2e-39 135.9 0.4 4.3 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EGD94907.1 - 9.4e-32 109.0 0.1 8.8e-12 45.1 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AATase PF07247.7 EGD94907.1 - 0.063 11.8 2.4 4.5 5.6 0.4 3.3 2 1 0 2 2 2 0 Alcohol acetyltransferase GH3 PF03321.8 EGD94907.1 - 0.12 10.8 0.0 16 3.8 0.0 2.7 3 0 0 3 3 3 0 GH3 auxin-responsive promoter HpaB PF03241.8 EGD94907.1 - 0.13 11.1 0.0 0.36 9.6 0.0 1.7 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Csm1 PF12539.3 EGD94907.1 - 0.14 12.6 0.3 11 6.5 0.0 2.9 2 0 0 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 Methyltransf_18 PF12847.2 EGD94908.1 - 1.4e-17 64.3 0.0 2.2e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD94908.1 - 6.9e-12 45.2 0.0 9.4e-11 41.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD94908.1 - 3.4e-05 23.8 0.0 5.8e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD94908.1 - 8.2e-05 22.3 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD94908.1 - 0.00019 21.8 0.0 0.00049 20.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD94908.1 - 0.0023 18.3 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD94908.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EGD94908.1 - 0.021 14.1 0.1 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.9 EGD94908.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EGD94909.1 - 0.00013 21.4 0.0 0.016 14.6 0.0 2.2 1 1 0 2 2 2 2 Putative methyltransferase zf-C2H2_4 PF13894.1 EGD94910.1 - 0.0099 16.1 1.7 0.03 14.6 1.2 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD94910.1 - 0.024 14.9 3.8 0.088 13.1 2.6 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type PHD PF00628.24 EGD94911.1 - 2.1e-09 36.8 9.9 4.5e-09 35.8 6.9 1.6 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EGD94911.1 - 2.7e-07 30.8 0.0 8.1e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Collagen PF01391.13 EGD94913.1 - 5.5e-07 29.0 9.6 1.4e-06 27.7 6.7 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) BAG PF02179.11 EGD94914.1 - 1.8e-07 31.1 0.0 3.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 BAG domain CDK2AP PF09806.4 EGD94914.1 - 1.6 8.8 10.3 0.3 11.2 2.7 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein LMBR1 PF04791.11 EGD94915.1 - 1e-36 126.5 1.2 1.5e-36 126.0 0.9 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein Ribosomal_60s PF00428.14 EGD94915.1 - 0.019 15.3 2.3 0.019 15.3 1.6 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Med15_fungi PF05397.7 EGD94916.1 - 2.1e-17 63.1 0.1 2.1e-17 63.1 0.1 6.9 7 1 1 8 8 8 1 Mediator complex subunit 15 Nuc_sug_transp PF04142.10 EGD94917.1 - 6e-08 32.0 2.6 1.1e-07 31.2 1.8 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EGD94917.1 - 5.6e-07 29.6 25.8 0.00016 21.7 4.0 3.4 2 1 1 3 3 3 3 EamA-like transporter family TPT PF03151.11 EGD94917.1 - 5e-06 26.2 15.5 0.00084 19.0 0.2 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EGD94917.1 - 0.00096 18.1 14.3 0.0052 15.7 9.9 1.9 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EGD94917.1 - 0.012 15.8 8.4 0.012 15.8 5.8 3.3 2 1 1 3 3 3 0 Multidrug resistance efflux transporter MBOAT PF03062.14 EGD94918.1 - 4.3e-35 121.3 10.8 4.3e-35 121.3 7.5 2.0 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Adaptin_N PF01602.15 EGD94919.1 - 2e-139 465.3 0.2 2.3e-139 465.1 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EGD94919.1 - 2e-20 73.2 0.0 4.2e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EGD94919.1 - 1.8e-08 34.5 0.8 0.011 15.9 0.0 4.5 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EGD94919.1 - 0.00025 20.8 1.1 13 6.1 0.0 4.9 4 1 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EGD94919.1 - 0.00097 19.5 0.3 6.9 7.2 0.0 4.5 3 0 0 3 3 3 1 HEAT-like repeat Arm PF00514.18 EGD94919.1 - 0.017 14.9 0.1 60 3.6 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 EGD94919.1 - 0.018 14.6 0.2 0.07 12.7 0.0 2.0 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 EGD94919.1 - 0.02 14.7 0.3 0.02 14.7 0.2 3.5 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.2 EGD94919.1 - 0.055 13.1 0.0 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus DnaJ PF00226.26 EGD94922.1 - 2.8e-21 75.0 1.2 5.8e-21 74.0 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain PRP38_assoc PF12871.2 EGD94922.1 - 0.00014 22.2 36.2 0.00014 22.2 25.1 5.7 4 1 1 5 5 5 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 EGD94922.1 - 0.00048 19.9 37.3 0.00048 19.9 25.9 3.9 3 1 0 3 3 3 1 Protein of unknown function (DUF1777) IgG_binding_B PF01378.12 EGD94923.1 - 0.1 12.4 0.3 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 B domain TraV PF09676.5 EGD94924.1 - 0.045 14.4 1.0 0.072 13.8 0.7 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Phage_tail_S PF05069.8 EGD94924.1 - 1.2 8.8 6.5 2.1 8.1 4.5 1.3 1 0 0 1 1 1 0 Phage virion morphogenesis family Peptidase_S49_N PF08496.5 EGD94924.1 - 9.6 5.9 9.0 15 5.3 6.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pyr_redox PF00070.22 EGD94926.1 - 2.3e-11 43.9 0.0 4.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD94926.1 - 9.6e-10 38.6 0.0 1.5e-08 34.8 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD94926.1 - 9.3e-06 25.8 0.1 3.1e-05 24.1 0.0 1.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD94926.1 - 3.6e-05 22.8 0.1 7.7e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EGD94926.1 - 0.00053 18.7 0.0 0.094 11.3 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.1 EGD94926.1 - 0.03 14.0 0.2 36 4.0 0.0 3.2 2 1 0 3 3 3 0 FAD-NAD(P)-binding Metallophos PF00149.23 EGD94927.1 - 1.9e-08 33.9 4.6 2.6e-07 30.2 2.7 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD94927.1 - 3.5e-08 33.4 0.1 7.5e-08 32.3 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.1 EGD94927.1 - 0.03 12.6 0.0 0.043 12.1 0.0 1.1 1 0 0 1 1 1 0 MutL protein Ribosomal_L13 PF00572.13 EGD94928.1 - 9.7e-28 96.7 0.0 1.7e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 AMP-binding PF00501.23 EGD94929.1 - 4e-70 236.3 0.0 4.7e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD94929.1 - 7.3e-14 52.4 0.1 1.4e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.15 EGD94929.1 - 0.0025 16.9 0.0 0.0053 15.8 0.0 1.5 1 0 0 1 1 1 1 LysR substrate binding domain LRR_4 PF12799.2 EGD94930.1 - 1.7e-11 43.4 7.1 0.078 12.6 0.0 7.1 3 2 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD94930.1 - 8.5e-11 41.4 14.5 0.01 15.5 1.3 6.3 3 1 3 6 6 6 4 Leucine rich repeat F-box-like PF12937.2 EGD94930.1 - 4e-10 39.2 1.5 4e-10 39.2 1.0 3.0 3 0 0 3 3 3 1 F-box-like LRR_1 PF00560.28 EGD94930.1 - 2e-06 27.0 19.9 3.4 8.0 0.0 10.5 7 4 1 8 8 8 1 Leucine Rich Repeat F-box PF00646.28 EGD94930.1 - 0.0015 18.1 8.5 0.0037 16.8 1.3 3.4 3 0 0 3 3 3 1 F-box domain Recep_L_domain PF01030.19 EGD94930.1 - 0.041 13.8 1.7 13 5.7 0.4 3.9 2 1 2 4 4 4 0 Receptor L domain Adeno_E4_34 PF04528.8 EGD94930.1 - 8.9 5.8 12.5 4.4 6.8 2.1 3.1 2 1 1 3 3 3 0 Adenovirus early E4 34 kDa protein conserved region Peptidase_M28 PF04389.12 EGD94931.1 - 1e-32 113.3 0.1 1.6e-32 112.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 ATP-synt_8 PF00895.15 EGD94931.1 - 0.034 14.3 0.1 0.034 14.3 0.0 5.2 6 2 1 7 7 7 0 ATP synthase protein 8 Med10 PF09748.4 EGD94933.1 - 2.8e-41 140.3 0.0 3.5e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 EGD94933.1 - 0.0095 15.5 0.0 0.022 14.3 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function, E. rectale Gene description (DUF3877) DUF3939 PF13075.1 EGD94933.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) FDX-ACB PF03147.9 EGD94933.1 - 0.13 12.4 0.1 5 7.3 0.0 2.3 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain Arch_ATPase PF01637.13 EGD94935.1 - 9e-05 22.2 0.1 0.00025 20.8 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 EGD94935.1 - 0.00028 21.1 0.0 0.035 14.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGD94935.1 - 0.00028 20.9 2.1 0.016 15.1 1.5 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGD94935.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EGD94935.1 - 0.022 13.6 0.0 0.048 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2859 PF11072.3 EGD94935.1 - 0.042 13.2 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) AAA_5 PF07728.9 EGD94935.1 - 0.072 12.8 0.0 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 EGD94935.1 - 0.095 13.1 0.0 0.44 11.0 0.0 2.2 1 1 0 1 1 1 0 Miro-like protein Metallophos_2 PF12850.2 EGD94936.1 - 1.3e-10 41.3 0.2 2.7e-10 40.2 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGD94936.1 - 4.7e-10 39.1 2.4 0.00021 20.7 0.4 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase FA_desaturase PF00487.19 EGD94937.1 - 0.077 12.4 0.0 0.093 12.1 0.0 1.0 1 0 0 1 1 1 0 Fatty acid desaturase CLU PF13236.1 EGD94938.1 - 1.6e-79 266.3 0.0 2.7e-79 265.6 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EGD94938.1 - 3.1e-55 186.6 0.0 8.7e-55 185.2 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EGD94938.1 - 7.5e-26 90.1 0.5 3.1e-25 88.1 0.2 2.1 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EGD94938.1 - 2.6e-25 88.1 3.0 9e-11 41.5 0.0 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EGD94938.1 - 1.3e-15 56.7 0.0 0.0021 17.9 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGD94938.1 - 9.8e-07 28.3 1.6 0.041 13.5 0.0 3.5 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EGD94938.1 - 8.6e-05 22.1 4.6 0.3 11.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGD94938.1 - 0.0005 19.6 0.9 0.6 10.0 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD94938.1 - 0.001 19.6 0.0 0.74 10.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGD94938.1 - 0.028 14.6 1.4 1.2e+02 3.2 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat FHIPEP PF00771.15 EGD94938.1 - 0.16 10.2 0.2 4.8 5.3 0.0 2.2 2 0 0 2 2 2 0 FHIPEP family Ferric_reduct PF01794.14 EGD94940.1 - 9.6e-18 64.4 11.4 9.6e-18 64.4 7.9 2.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EGD94940.1 - 2.2e-17 63.3 0.0 7.2e-15 55.2 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGD94940.1 - 5.6e-15 55.0 0.0 2.2e-14 53.1 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain GST_N_3 PF13417.1 EGD94941.1 - 3.6e-15 55.9 0.0 5.9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD94941.1 - 1.4e-11 44.2 0.0 2.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD94941.1 - 1.1e-10 41.2 0.0 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD94941.1 - 1.3e-10 41.3 0.0 2.7e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD94941.1 - 1.1e-09 38.0 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD94941.1 - 4e-08 33.6 0.3 7.2e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glyco_trans_1_2 PF13524.1 EGD94941.1 - 0.15 12.3 0.1 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 zf-CCHC PF00098.18 EGD94942.1 - 3.2e-11 42.5 10.0 3.9e-05 23.3 2.1 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EGD94942.1 - 2.8e-07 30.0 0.2 5.8e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EGD94942.1 - 2.6e-06 27.0 6.5 0.00059 19.5 1.9 2.6 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EGD94942.1 - 9.7e-05 21.9 0.2 0.00024 20.6 0.1 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EGD94942.1 - 0.00039 20.0 6.2 0.15 11.7 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EGD94942.1 - 0.01 15.4 9.7 0.43 10.2 0.5 2.9 3 0 0 3 3 3 0 Zinc knuckle DUF3716 PF12511.3 EGD94943.1 - 3.8e-05 23.1 0.4 6.4e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) C1_1 PF00130.17 EGD94943.1 - 0.074 12.7 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HCO3_cotransp PF00955.16 EGD94944.1 - 8.5e-69 232.5 14.0 2.2e-40 138.8 3.8 2.0 1 1 1 2 2 2 2 HCO3- transporter family DEAD PF00270.24 EGD94945.1 - 7.6e-40 136.1 0.0 2.1e-39 134.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD94945.1 - 5.3e-26 90.2 0.1 1e-25 89.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGD94945.1 - 0.00016 20.5 0.0 0.00027 19.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGD94945.1 - 0.018 14.8 0.0 0.06 13.1 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit FRG2 PF15315.1 EGD94945.1 - 0.09 12.7 1.2 0.17 11.8 0.9 1.4 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 tRNA-synt_1c PF00749.16 EGD94949.1 - 2.8e-97 325.1 0.0 3.8e-97 324.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGD94949.1 - 8.3e-21 74.4 0.0 1.4e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EGD94949.1 - 6.8e-07 29.7 0.0 1.8e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGD94949.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGD94949.1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1793 PF08760.6 EGD94950.1 - 1.8e-71 239.4 0.1 3.3e-71 238.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Stm1_N PF09598.5 EGD94952.1 - 1.6e-13 51.1 6.2 1.6e-13 51.1 4.3 4.7 3 1 0 3 3 3 1 Stm1 API5 PF05918.6 EGD94952.1 - 1.2 7.5 7.9 1.8 6.9 5.4 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TATR PF03430.8 EGD94952.1 - 3.9 6.0 7.7 4.8 5.6 5.3 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator bZIP_1 PF00170.16 EGD94953.1 - 3.7e-06 26.8 8.4 7.8e-06 25.7 5.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGD94953.1 - 0.0092 15.7 8.0 0.0092 15.7 5.5 2.1 3 0 0 3 3 3 1 Basic region leucine zipper GvpL_GvpF PF06386.6 EGD94953.1 - 0.14 11.7 1.7 0.24 10.9 1.2 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Glutaredoxin2_C PF04399.8 EGD94953.1 - 0.15 11.6 0.6 0.29 10.7 0.4 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF4407 PF14362.1 EGD94953.1 - 0.41 9.5 3.1 0.32 9.9 1.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_Maf PF03131.12 EGD94953.1 - 1 9.7 8.8 1.6 9.0 4.8 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Lgl_C PF08596.5 EGD94955.1 - 4.6e-121 403.9 0.0 6.9e-120 400.1 0.0 2.3 3 0 0 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EGD94955.1 - 0.0094 15.8 1.3 34 4.5 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat APH PF01636.18 EGD94956.1 - 0.00041 20.1 0.0 0.00059 19.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family THUMP PF02926.12 EGD94957.1 - 1.5e-07 31.4 0.0 2.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 THUMP domain TPP_enzyme_N PF02776.13 EGD94958.1 - 4.7e-34 117.3 0.0 6.8e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGD94958.1 - 5.4e-24 84.5 0.0 2.1e-23 82.6 0.0 2.0 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EGD94958.1 - 1.1e-14 54.3 0.0 2.6e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EGD94958.1 - 0.0013 17.5 0.0 0.0024 16.6 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component FmdA_AmdA PF03069.10 EGD94958.1 - 0.12 11.0 0.0 2.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Acetamidase/Formamidase family Bromodomain PF00439.20 EGD94959.1 - 1e-18 67.0 0.2 1e-18 67.0 0.1 2.3 3 0 0 3 3 3 1 Bromodomain Bromo_TP PF07524.8 EGD94959.1 - 1.6e-08 34.1 0.0 4.6e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated NADH_Oxid_Nqo15 PF11497.3 EGD94959.1 - 0.075 12.7 0.1 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 VanZ PF04892.7 EGD94960.1 - 4.4e-12 46.0 0.1 5.8e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 VanZ like family Y_phosphatase PF00102.22 EGD94961.1 - 1.8e-55 187.8 0.0 2.4e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGD94961.1 - 0.00061 19.8 0.0 0.0021 18.1 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EGD94961.1 - 0.0053 17.0 0.0 0.0099 16.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EGD94961.1 - 0.0066 16.0 0.1 0.019 14.5 0.1 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Piwi PF02171.12 EGD94962.1 - 8e-67 225.3 0.0 1.5e-66 224.4 0.0 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EGD94962.1 - 4.2e-15 55.2 1.0 7.5e-15 54.4 0.7 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EGD94962.1 - 1.1e-11 43.8 0.5 2.8e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PerB PF06590.6 EGD94962.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 PerB protein Herpes_US9 PF06072.6 EGD94964.1 - 0.018 14.8 3.3 0.018 14.8 2.3 1.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF2116 PF09889.4 EGD94964.1 - 0.79 9.5 3.4 1.4 8.7 2.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TSP_1 PF00090.14 EGD94966.1 - 0.12 12.5 0.2 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 Thrombospondin type 1 domain Sugar_tr PF00083.19 EGD94967.1 - 4.8e-71 239.6 15.8 3.7e-70 236.7 10.7 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD94967.1 - 8.1e-10 37.9 28.1 1.9e-09 36.7 19.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UAA PF08449.6 EGD94967.1 - 0.0019 17.1 0.3 0.004 16.1 0.2 1.4 1 0 0 1 1 1 1 UAA transporter family RNase_T PF00929.19 EGD94970.1 - 1e-26 94.1 0.0 1.2e-26 93.9 0.0 1.0 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.11 EGD94971.1 - 9.7e-34 115.8 0.1 1.4e-33 115.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EGD94971.1 - 7.7e-25 87.1 0.0 1.4e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EGD94971.1 - 1.1e-16 60.9 0.1 3.1e-16 59.5 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGD94971.1 - 1.8e-10 40.6 0.0 4.4e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.17 EGD94972.1 - 1.1e-10 42.0 0.0 2.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGD94972.1 - 0.0027 17.4 0.0 0.008 15.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain HMG_CoA_synt_C PF08540.5 EGD94974.1 - 6.1e-102 340.8 0.2 7.6e-102 340.5 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EGD94974.1 - 1.8e-94 314.1 0.1 3e-94 313.4 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 EGD94974.1 - 0.11 11.7 0.4 0.36 10.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) TFR_dimer PF04253.10 EGD94975.1 - 1.1e-26 92.8 0.1 1.9e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EGD94975.1 - 3.4e-12 46.4 0.0 6.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EGD94975.1 - 1.7e-08 34.1 0.1 3.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 PA domain TFIIB PF00382.14 EGD94976.1 - 1.8e-20 72.4 0.1 3.8e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGD94976.1 - 1.6e-10 40.1 1.0 1.6e-10 40.1 0.7 1.9 2 0 0 2 2 2 1 TFIIB zinc-binding DZR PF12773.2 EGD94976.1 - 0.055 13.2 1.3 0.28 11.0 0.1 2.2 2 0 0 2 2 2 0 Double zinc ribbon RB_B PF01857.15 EGD94976.1 - 0.099 12.1 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain DUF1610 PF07754.6 EGD94976.1 - 0.14 12.2 1.5 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.1 EGD94976.1 - 0.85 8.9 4.6 0.2 10.9 0.5 1.9 2 0 0 2 2 2 0 zinc-ribbon domain ATP_sub_h PF10775.4 EGD94977.1 - 4.2e-26 90.4 1.8 6.8e-26 89.7 1.2 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EGD94977.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Dscam_C PF12355.3 EGD94978.1 - 0.3 11.3 4.2 0.45 10.7 2.9 1.5 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Agouti PF05039.7 EGD94978.1 - 5.6 7.3 7.2 10 6.5 0.4 2.1 1 1 1 2 2 2 0 Agouti protein Remorin_N PF03766.8 EGD94978.1 - 6.9 6.5 10.0 2.1 8.1 1.9 2.3 2 0 0 2 2 2 0 Remorin, N-terminal region DUF1765 PF08578.5 EGD94979.1 - 2.4e-41 140.7 0.6 4.9e-41 139.7 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Surp PF01805.15 EGD94980.1 - 2e-16 59.3 0.0 3.8e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Surp module DUF3914 PF13053.1 EGD94980.1 - 0.043 13.9 0.1 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) NTF2 PF02136.15 EGD94981.1 - 6.2e-33 113.6 0.1 6.9e-33 113.5 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EGD94981.1 - 0.028 14.2 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Cg6151-P PF10233.4 EGD94982.1 - 6.5e-36 122.7 11.2 7.8e-36 122.4 7.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF454 PF04304.8 EGD94982.1 - 0.071 13.1 0.5 0.071 13.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Trep_Strep PF09605.5 EGD94982.1 - 0.93 9.1 9.4 0.089 12.4 0.5 2.1 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF2721 PF11026.3 EGD94982.1 - 1.5 8.4 11.1 0.22 11.1 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF3210 PF11489.3 EGD94983.1 - 5e-133 445.3 91.8 6.9e-114 382.0 49.6 3.2 3 1 1 4 4 4 2 Protein of unknown function (DUF3210) FAD_binding_4 PF01565.18 EGD94984.1 - 1.9e-22 79.2 2.5 3.1e-22 78.5 1.8 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD94984.1 - 1.5e-08 34.4 0.1 3.2e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF2951 PF11166.3 EGD94986.1 - 0.28 11.0 0.0 0.28 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) RdRP_1 PF00680.15 EGD94987.1 - 0.062 11.5 1.6 0.068 11.4 1.1 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF2489 PF10675.4 EGD94987.1 - 0.14 11.8 2.3 0.22 11.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Nucleo_P87 PF07267.6 EGD94987.1 - 0.77 8.3 7.1 0.81 8.2 4.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CCDC-167 PF15188.1 EGD94987.1 - 6.2 6.8 9.2 4.9 7.1 4.0 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 PQ-loop PF04193.9 EGD94988.1 - 5.5e-19 67.4 16.9 1e-11 44.1 2.5 3.7 4 0 0 4 4 4 2 PQ loop repeat Arteri_GP4 PF02497.10 EGD94988.1 - 0.041 13.7 0.1 0.095 12.6 0.1 1.5 1 1 0 1 1 1 0 Arterivirus glycoprotein TrbC PF04956.8 EGD94988.1 - 0.23 11.4 6.7 0.14 12.1 2.4 2.3 1 1 1 2 2 2 0 TrbC/VIRB2 family ATP-synt_8 PF00895.15 EGD94988.1 - 0.24 11.6 2.3 3.6 7.8 0.3 3.0 3 0 0 3 3 3 0 ATP synthase protein 8 OppC_N PF12911.2 EGD94988.1 - 0.74 9.2 5.1 1.4 8.3 0.0 3.1 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Ish1 PF10281.4 EGD94989.1 - 2.3e-75 248.1 18.4 6.1e-14 51.7 0.0 7.6 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EGD94989.1 - 5.1e-09 35.5 0.1 1.2 8.7 0.0 5.3 5 0 0 5 5 5 4 HeH/LEM domain SAP PF02037.22 EGD94989.1 - 1e-06 28.1 0.0 0.44 10.1 0.0 4.5 4 0 0 4 4 4 2 SAP domain Slx4 PF09494.5 EGD94989.1 - 2.6e-05 23.8 0.5 7.9 6.3 0.0 5.0 6 0 0 6 6 6 2 Slx4 endonuclease APC2 PF08672.6 EGD94989.1 - 0.006 16.8 2.9 30 4.9 0.0 5.6 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 LEM PF03020.10 EGD94989.1 - 0.026 13.9 0.0 52 3.4 0.0 4.0 4 0 0 4 4 4 0 LEM domain Recombinase PF07508.8 EGD94989.1 - 0.047 13.9 2.0 2.4 8.4 0.0 3.6 3 1 1 4 4 4 0 Recombinase Cyt-b5 PF00173.23 EGD94990.1 - 6.9e-15 54.6 0.0 9.5e-15 54.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fib_alpha PF08702.5 EGD94991.1 - 0.042 13.9 3.7 0.081 13.0 2.2 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Filament PF00038.16 EGD94991.1 - 0.074 12.5 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Intermediate filament protein Baculo_PEP_C PF04513.7 EGD94991.1 - 0.095 12.5 1.0 0.18 11.6 0.7 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DHC_N2 PF08393.8 EGD94991.1 - 0.15 10.5 0.4 0.21 10.0 0.3 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 TMA7 PF09072.5 EGD94992.1 - 8.1e-24 83.8 22.6 9.1e-24 83.7 15.7 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.20 EGD94993.1 - 1.8e-54 184.5 0.0 2.9e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94993.1 - 1.6e-23 83.0 0.0 1.1e-22 80.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGD94993.1 - 0.013 14.3 0.2 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EGD94993.1 - 0.038 12.9 0.0 0.87 8.4 0.0 2.5 2 1 0 2 2 2 0 Kinase-like Pkinase PF00069.20 EGD94999.1 - 5e-60 202.8 0.0 6.5e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD94999.1 - 1.6e-32 112.6 0.0 2e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD94999.1 - 0.001 18.1 0.0 0.0037 16.2 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EGD94999.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGD94999.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 EGD95000.1 - 8.2e-35 120.1 3.2 8.2e-35 120.1 2.3 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD95000.1 - 1.3e-26 93.8 0.6 2.2e-26 93.0 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD95000.1 - 6.2e-18 65.1 0.9 8.4e-18 64.6 0.6 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EGD95000.1 - 0.0038 16.9 0.8 0.0062 16.1 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_26 PF13659.1 EGD95000.1 - 0.018 15.0 0.1 0.039 13.9 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.16 EGD95000.1 - 0.029 14.2 0.5 0.077 12.8 0.3 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.16 EGD95000.1 - 0.039 13.3 0.2 0.053 12.9 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGD95000.1 - 0.085 11.7 0.6 0.27 10.0 0.4 1.9 1 1 0 1 1 1 0 RmlD substrate binding domain HlyIII PF03006.15 EGD95001.1 - 1.6e-59 201.0 14.3 1.9e-59 200.7 9.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related Trp_oprn_chp PF09534.5 EGD95001.1 - 6.9 6.2 9.7 7.9 6.0 2.1 3.1 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SAC3_GANP PF03399.11 EGD95002.1 - 0.0064 16.0 0.2 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF4129 PF13559.1 EGD95002.1 - 0.063 13.2 0.1 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) TPR_19 PF14559.1 EGD95003.1 - 2.1e-07 31.1 0.0 0.0043 17.3 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGD95003.1 - 2.9e-05 24.6 0.0 0.52 11.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD95003.1 - 8.6e-05 22.8 0.6 20 6.2 0.0 5.0 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD95003.1 - 0.0024 18.2 0.0 7.9 7.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGD95003.1 - 0.0059 16.5 0.1 4.4 7.3 0.0 3.1 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD95003.1 - 0.016 14.8 0.0 0.34 10.5 0.0 3.0 2 2 1 3 3 3 0 TPR repeat DUF4332 PF14229.1 EGD95003.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) TPR_4 PF07721.9 EGD95003.1 - 0.02 15.2 0.2 32 5.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.21 EGD95004.1 - 5.1e-34 117.3 0.0 6.3e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGD95004.1 - 2.6e-15 56.8 0.0 3.5e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EGD95004.1 - 3.6e-10 39.3 0.0 6.3e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGD95004.1 - 0.00048 19.4 0.0 0.0007 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF1749 PF08538.5 EGD95005.1 - 6.3e-91 304.4 0.0 7.1e-91 304.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EGD95005.1 - 4.8e-05 23.3 0.0 7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD95005.1 - 0.00042 20.0 0.0 0.00097 18.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EGD95005.1 - 0.0016 18.1 0.0 0.034 13.7 0.0 2.5 2 0 0 2 2 2 1 Serine hydrolase DUF900 PF05990.7 EGD95005.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) WD40 PF00400.27 EGD95006.1 - 3 7.8 9.4 46 4.1 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Vps35 PF03635.12 EGD95008.1 - 0 1014.8 0.3 0 1014.6 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 NST1 PF13945.1 EGD95009.1 - 7.5e-73 244.6 3.5 7.5e-73 244.6 2.4 4.6 3 1 1 4 4 4 1 Salt tolerance down-regulator Ras PF00071.17 EGD95010.1 - 3.7e-47 159.7 0.0 4.3e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD95010.1 - 2.3e-16 60.3 0.0 3.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD95010.1 - 2.4e-06 26.9 0.0 3.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGD95010.1 - 0.0033 16.6 0.0 0.0042 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGD95010.1 - 0.017 14.2 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGD95010.1 - 0.018 14.5 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MRP-L28 PF09812.4 EGD95011.1 - 6.4e-07 29.3 0.2 8.6e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RINGv PF12906.2 EGD95012.1 - 2.6e-06 27.3 5.3 6.1e-06 26.1 3.7 1.7 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EGD95012.1 - 3.4e-06 26.9 2.4 7.6e-06 25.7 1.7 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EGD95012.1 - 0.00085 19.1 3.7 0.0019 17.9 2.6 1.6 1 0 0 1 1 1 1 Ring finger domain PhnA_Zn_Ribbon PF08274.7 EGD95012.1 - 0.013 15.2 1.7 0.031 14.0 1.2 1.7 1 0 0 1 1 1 0 PhnA Zinc-Ribbon TPP_enzyme_C PF02775.16 EGD95013.1 - 2.9e-47 160.0 0.2 1.2e-46 158.1 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGD95013.1 - 5.9e-38 129.7 0.3 1.5e-37 128.3 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 EGD95013.1 - 2e-32 112.0 0.4 2.7e-30 105.1 0.0 3.2 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain GalKase_gal_bdg PF10509.4 EGD95014.1 - 1.1e-18 66.2 0.0 2.1e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EGD95014.1 - 4.8e-14 52.1 1.2 1.3e-13 50.8 0.8 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGD95014.1 - 7.4e-11 42.1 0.0 2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Crp PF00325.15 EGD95014.1 - 0.16 11.4 0.4 4.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family RNase_H2-Ydr279 PF09468.5 EGD95015.1 - 8.5e-68 228.7 10.9 5.1e-66 222.9 7.6 2.1 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Selenoprotein_S PF06936.6 EGD95015.1 - 6.8 6.1 9.8 0.32 10.5 2.1 2.0 2 0 0 2 2 2 0 Selenoprotein S (SelS) zf-primase PF09329.6 EGD95016.1 - 1.4e-19 69.4 0.6 2.4e-19 68.6 0.4 1.4 1 0 0 1 1 1 1 Primase zinc finger DASH_Duo1 PF08651.5 EGD95018.1 - 2.5e-29 100.6 0.2 4.2e-29 99.9 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 PEARLI-4 PF05278.7 EGD95018.1 - 0.019 14.3 4.4 0.039 13.3 3.0 1.5 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF745 PF05335.8 EGD95018.1 - 0.019 14.4 7.1 0.034 13.6 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) 3HCDH_N PF02737.13 EGD95018.1 - 0.21 11.2 4.3 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-synt_E PF05680.7 EGD95018.1 - 2.4 8.1 7.3 0.75 9.7 2.5 2.1 2 0 0 2 2 2 0 ATP synthase E chain Tic20 PF09685.5 EGD95019.1 - 3.6e-07 30.1 1.9 4.8e-07 29.7 1.3 1.2 1 0 0 1 1 1 1 Tic20-like protein SH3_1 PF00018.23 EGD95020.1 - 3.3e-13 48.7 0.0 6.9e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGD95020.1 - 1e-10 40.9 0.0 3.2e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EGD95020.1 - 1.2e-10 40.8 0.0 4.8e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain FCH PF00611.18 EGD95021.1 - 2.9e-21 75.4 0.0 9.5e-21 73.8 0.0 1.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Glyco_hydro_15 PF00723.16 EGD95021.1 - 0.0021 16.7 0.2 0.003 16.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Rapsyn_N PF10579.4 EGD95021.1 - 0.012 15.3 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region Feld-I_B PF09252.5 EGD95021.1 - 0.19 11.6 0.5 8.2 6.4 0.0 2.7 2 1 1 3 3 3 0 Allergen Fel d I-B chain Not1 PF04054.10 EGD95022.1 - 1.2e-138 462.0 0.3 1.2e-138 462.0 0.2 2.5 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EGD95022.1 - 1.8e-50 170.4 1.2 4.7e-50 169.1 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) TTL PF03133.10 EGD95023.1 - 2.2e-55 187.6 0.0 3.3e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EGD95023.1 - 4.6e-29 101.1 0.0 7.1e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 EGD95023.1 - 0.058 13.1 0.1 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EGD95023.1 - 0.1 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 EGD95023.1 - 0.19 11.1 0.0 2 7.7 0.0 2.1 1 1 1 2 2 2 0 D-ala D-ala ligase C-terminus ABC_tran PF00005.22 EGD95025.1 - 1.3e-33 116.2 0.0 2.2e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGD95025.1 - 4.3e-18 65.7 0.8 4.3e-18 65.7 0.5 2.1 2 1 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EGD95025.1 - 2.7e-05 23.5 0.1 0.0019 17.4 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD95025.1 - 0.00021 21.3 0.0 0.17 11.7 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGD95025.1 - 0.011 15.2 0.3 0.03 13.8 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EGD95025.1 - 0.011 16.0 0.5 0.038 14.3 0.3 1.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EGD95025.1 - 0.014 15.2 0.1 0.076 12.9 0.0 2.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EGD95025.1 - 0.041 13.0 0.0 0.085 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGD95025.1 - 0.042 14.0 0.0 0.15 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGD95025.1 - 0.064 12.6 0.1 0.11 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain Pex14_N PF04695.8 EGD95027.1 - 5.4e-40 136.5 0.0 5.4e-40 136.5 0.0 3.2 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.7 EGD95027.1 - 0.31 10.8 1.9 1.1 9.1 1.1 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 EGD95027.1 - 7.3 3.7 14.1 0.017 12.5 3.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Ndc80_HEC PF03801.8 EGD95028.1 - 3.4e-63 211.8 0.4 8.4e-63 210.5 0.3 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family Pkinase PF00069.20 EGD95030.1 - 9.4e-55 185.5 0.0 2.1e-54 184.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95030.1 - 1.3e-21 76.9 0.0 3.1e-21 75.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD95030.1 - 0.032 13.9 0.9 2.3 7.9 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family FolB PF02152.13 EGD95031.1 - 4.2e-23 81.6 0.2 8e-19 67.8 0.2 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase RRM_1 PF00076.17 EGD95032.1 - 1.3e-17 63.1 0.1 8.6e-08 31.7 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD95032.1 - 2.2e-12 46.6 0.0 5.3e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD95032.1 - 1.7e-11 43.9 0.0 0.00011 22.0 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGD95032.1 - 0.063 13.1 0.0 1.7 8.5 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif CSD PF00313.17 EGD95032.1 - 0.19 11.5 0.7 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain ETF_QO PF05187.8 EGD95033.1 - 2.5e-45 153.0 0.0 4.1e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EGD95033.1 - 4.1e-11 42.3 0.0 3.6e-05 22.8 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD95033.1 - 3e-05 23.9 0.0 7.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGD95033.1 - 3.1e-05 23.0 0.0 0.0021 16.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EGD95033.1 - 0.00019 20.6 0.0 0.00033 19.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGD95033.1 - 0.00059 20.1 0.0 0.94 9.9 0.0 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD95033.1 - 0.00079 18.0 0.1 0.0012 17.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 EGD95033.1 - 0.00085 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EGD95033.1 - 0.00087 18.4 0.3 0.0017 17.5 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 EGD95033.1 - 0.0014 17.3 0.0 0.025 13.2 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 EGD95033.1 - 0.0032 16.6 0.0 0.0071 15.4 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EGD95033.1 - 0.0038 17.1 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD95033.1 - 0.0093 16.0 0.0 0.044 13.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGD95033.1 - 0.076 11.9 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EGD95033.1 - 0.14 11.0 0.4 0.21 10.4 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TBP PF00352.16 EGD95034.1 - 3.9e-70 231.2 0.1 3.8e-35 119.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EGD95034.1 - 0.0001 22.2 0.0 0.41 10.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DAO PF01266.19 EGD95035.1 - 3.2e-56 190.7 0.3 4e-56 190.4 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGD95035.1 - 3.1e-07 30.4 0.1 0.00038 20.4 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGD95035.1 - 4.7e-06 25.5 0.4 0.019 13.6 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.17 EGD95035.1 - 5.3e-06 25.5 0.1 6.5e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EGD95035.1 - 7.4e-06 25.8 0.3 0.049 13.4 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGD95035.1 - 7e-05 22.7 0.0 0.00024 21.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EGD95035.1 - 0.001 18.1 0.2 0.4 9.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 EGD95035.1 - 0.0013 17.7 0.7 0.78 8.5 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EGD95035.1 - 0.0015 18.6 1.0 0.55 10.2 0.1 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGD95035.1 - 0.0031 16.4 0.1 0.066 12.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EGD95035.1 - 0.0036 17.6 0.0 0.0096 16.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EGD95035.1 - 0.039 13.0 0.0 1.4 7.9 0.0 2.6 3 0 0 3 3 3 0 GMC oxidoreductase MCPVI PF02993.9 EGD95035.1 - 0.043 13.9 0.3 0.089 12.9 0.0 1.6 2 0 0 2 2 2 0 Minor capsid protein VI SR-25 PF10500.4 EGD95035.1 - 2.8 7.3 6.9 4.1 6.8 3.8 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Methyltransf_23 PF13489.1 EGD95036.1 - 2.4e-17 63.1 0.0 3.5e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD95036.1 - 0.015 15.7 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGD95036.1 - 0.04 14.2 0.0 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGD95036.1 - 0.061 13.8 0.0 0.17 12.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain CENP-B_dimeris PF09026.5 EGD95037.1 - 0.12 12.6 6.2 0.35 11.1 4.3 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Zip PF02535.17 EGD95037.1 - 0.39 9.6 4.2 0.59 9.0 2.9 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter Cyclin_N PF00134.18 EGD95038.1 - 7.9e-16 57.7 0.1 1.6e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGD95038.1 - 6.2e-07 29.3 0.0 8.2e-05 22.5 0.0 2.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EGD95038.1 - 0.004 16.9 2.0 0.083 12.7 0.0 2.5 2 0 0 2 2 2 1 Transcription factor TFIIB repeat DUF4603 PF15376.1 EGD95038.1 - 0.98 6.5 8.7 1.5 5.9 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) SOG2 PF10428.4 EGD95038.1 - 1.7 7.1 19.6 1.4 7.5 10.6 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Macoilin PF09726.4 EGD95038.1 - 3.9 5.6 7.2 6 5.0 5.0 1.2 1 0 0 1 1 1 0 Transmembrane protein EAF PF09816.4 EGD95039.1 - 8.2e-18 64.3 0.0 8.2e-18 64.3 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Pep_M12B_propep PF01562.14 EGD95039.1 - 0.008 15.9 0.8 5.8 6.7 0.9 2.5 2 0 0 2 2 2 2 Reprolysin family propeptide Dor1 PF04124.7 EGD95040.1 - 1.3e-52 178.4 0.6 6.1e-43 146.5 0.4 2.5 1 1 1 2 2 2 2 Dor1-like family Vps51 PF08700.6 EGD95040.1 - 0.034 13.9 2.3 0.063 13.1 0.3 2.3 2 0 0 2 2 2 0 Vps51/Vps67 DUF4515 PF14988.1 EGD95040.1 - 0.051 13.2 0.2 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) RIC1 PF07064.8 EGD95040.1 - 0.09 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 RIC1 ApoLp-III PF07464.6 EGD95040.1 - 0.11 12.5 0.5 4.3 7.3 0.2 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Sec8_exocyst PF04048.9 EGD95040.1 - 0.12 12.0 1.9 0.19 11.3 0.5 1.9 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Snf7 PF03357.16 EGD95040.1 - 3.7 6.9 6.5 0.18 11.1 0.5 1.8 2 0 0 2 2 2 0 Snf7 His_Phos_1 PF00300.17 EGD95041.1 - 1.3e-33 116.3 0.0 2.4e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EGD95041.1 - 1.2e-05 24.7 0.0 2.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Nucleoplasmin PF03066.10 EGD95041.1 - 2.9 7.3 10.1 3.2 7.2 2.1 2.2 2 0 0 2 2 2 0 Nucleoplasmin YL1 PF05764.8 EGD95041.1 - 5 6.6 10.7 0.14 11.7 2.8 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Zn_clus PF00172.13 EGD95042.1 - 3.5e-07 30.0 6.7 3.5e-07 30.0 4.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGD95042.1 - 1.2e-05 24.1 3.3 2e-05 23.3 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 EGD95043.1 - 3e-12 46.9 0.0 5e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD95043.1 - 5.9e-07 29.3 0.0 8.1e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD95043.1 - 0.00084 18.9 0.1 0.0046 16.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD95043.1 - 0.02 14.0 0.1 6.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family COX6A PF02046.10 EGD95044.1 - 0.64 9.9 2.7 1 9.2 1.9 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIa Peptidase_M43 PF05572.8 EGD95046.1 - 3.8e-17 62.2 0.2 6.9e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EGD95046.1 - 9.5e-06 26.1 1.5 5.2e-05 23.7 1.0 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EGD95046.1 - 1.6e-05 24.8 2.6 4.1e-05 23.5 1.8 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EGD95046.1 - 0.00016 21.7 4.5 0.0003 20.9 3.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EGD95046.1 - 0.00038 20.0 5.9 0.0045 16.5 2.7 2.4 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EGD95046.1 - 0.006 16.3 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EGD95046.1 - 0.051 12.4 1.7 0.072 11.9 1.1 1.4 1 1 0 1 1 1 0 Peptidase M66 Astacin PF01400.19 EGD95046.1 - 0.087 12.2 0.1 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M7 PF02031.11 EGD95046.1 - 0.23 11.1 2.7 0.16 11.6 0.5 1.7 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M57 PF12388.3 EGD95046.1 - 0.24 10.6 2.4 0.16 11.2 0.5 1.5 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase MAM PF00629.18 EGD95047.1 - 0.28 10.9 1.3 8.6 6.1 0.7 2.4 2 0 0 2 2 2 0 MAM domain DUF747 PF05346.6 EGD95048.1 - 1.2e-125 418.9 9.3 1.7e-125 418.4 6.5 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family p450 PF00067.17 EGD95049.1 - 1.7e-70 237.8 0.0 2e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M20 PF01546.23 EGD95050.1 - 6.4e-22 77.9 0.0 3.1e-21 75.7 0.0 2.1 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EGD95050.1 - 1.2e-20 72.5 8.2 8.1e-06 25.5 0.0 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat M20_dimer PF07687.9 EGD95050.1 - 0.00021 21.0 0.0 0.00045 19.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain MtN3_slv PF03083.11 EGD95051.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange TraQ PF09679.5 EGD95052.1 - 0.017 15.0 0.5 0.091 12.6 0.0 2.2 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Dsh_C PF12316.3 EGD95052.1 - 7.4 6.6 20.1 3.2 7.8 5.2 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Tim17 PF02466.14 EGD95053.1 - 1.8e-34 118.5 6.9 2.2e-34 118.2 4.8 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Asparaginase_2 PF01112.13 EGD95054.1 - 9.4e-39 132.9 0.0 8.7e-38 129.8 0.0 2.4 1 1 0 1 1 1 1 Asparaginase p450 PF00067.17 EGD95055.1 - 1.3e-52 178.9 0.0 1.9e-29 102.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Peptidase_S8 PF00082.17 EGD95057.1 - 1.4e-46 158.9 8.7 2.2e-46 158.2 6.1 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD95057.1 - 1.4e-16 60.8 0.1 2.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Flavoprotein PF02441.14 EGD95058.1 - 1.4e-10 40.9 0.0 2.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.1 EGD95058.1 - 0.023 15.2 0.2 1.2e+02 3.4 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Dimer_Tnp_hAT PF05699.9 EGD95058.1 - 8.4 6.0 8.0 5.4 6.7 0.0 3.9 5 1 1 6 6 6 0 hAT family C-terminal dimerisation region MFS_1 PF07690.11 EGD95059.1 - 2.6e-45 154.6 45.7 2.6e-45 154.6 31.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD95059.1 - 1.7e-14 53.2 15.1 1.7e-14 53.2 10.5 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter RICTOR_V PF14668.1 EGD95059.1 - 0.0088 15.9 0.0 0.034 14.0 0.0 2.0 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 Cerato-platanin PF07249.7 EGD95060.1 - 5.3e-43 145.8 0.3 6.6e-43 145.5 0.2 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 EGD95060.1 - 0.0036 16.9 0.2 0.0057 16.3 0.1 1.6 1 1 0 1 1 1 1 Barwin family GLTT PF01744.15 EGD95060.1 - 0.32 10.4 3.4 0.48 9.8 0.7 2.2 2 0 0 2 2 2 0 GLTT repeat (6 copies) DUF1542 PF07564.6 EGD95061.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Sulfotransfer_3 PF13469.1 EGD95061.1 - 0.13 13.2 0.1 0.65 10.9 0.0 2.0 1 1 0 1 1 1 0 Sulfotransferase family D123 PF07065.9 EGD95062.1 - 0.0018 17.4 0.0 0.0049 15.9 0.0 1.7 1 1 0 1 1 1 1 D123 DUF4343 PF14243.1 EGD95062.1 - 0.03 14.1 0.0 0.09 12.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4343) DUF2011 PF09428.5 EGD95064.1 - 4.2e-41 139.9 6.5 6.8e-41 139.2 4.5 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) RR_TM4-6 PF06459.7 EGD95064.1 - 4.9 6.9 12.5 1.5 8.6 3.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SOBP PF15279.1 EGD95064.1 - 5.4 7.3 8.5 0.74 10.1 2.2 1.9 2 0 0 2 2 2 0 Sine oculis-binding protein LAMTOR PF15454.1 EGD95065.1 - 1.3e-18 67.0 1.0 2.5e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator UQ_con PF00179.21 EGD95067.1 - 9.8e-36 122.2 0.8 4.7e-35 120.0 0.2 1.9 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme Phtf-FEM1B_bdg PF12129.3 EGD95068.1 - 0.24 10.7 1.0 0.38 10.0 0.7 1.4 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Pox_P21 PF05313.7 EGD95068.1 - 6 6.0 10.5 0.22 10.7 1.0 2.7 3 0 0 3 3 3 0 Poxvirus P21 membrane protein APG12 PF04110.8 EGD95070.1 - 5e-27 93.9 0.0 7.4e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EGD95070.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 EGD95071.1 - 8.8e-105 349.5 1.7 1.1e-104 349.2 1.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EGD95071.1 - 6.3e-11 41.9 1.8 1.5e-10 40.6 1.2 1.7 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Peptidase_M20 PF01546.23 EGD95071.1 - 0.12 11.8 0.7 9.6 5.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 Dfp1_Him1_M PF08630.5 EGD95072.1 - 3.1e-36 123.8 0.1 8.7e-36 122.4 0.0 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EGD95072.1 - 1.3e-20 72.7 0.4 1.3e-20 72.7 0.3 1.7 2 0 0 2 2 2 1 DBF zinc finger BRCT PF00533.21 EGD95072.1 - 0.00081 19.4 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGD95072.1 - 0.0066 16.2 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain AMP_N PF05195.11 EGD95073.1 - 1.7e-35 121.3 0.0 3.3e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.19 EGD95073.1 - 2.2e-35 122.1 0.0 1.3e-32 113.0 0.0 2.5 1 1 0 1 1 1 1 Metallopeptidase family M24 FR47 PF08445.5 EGD95074.1 - 3.6e-09 36.2 0.1 1.7e-06 27.7 0.1 2.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EGD95074.1 - 3.8e-08 33.6 0.2 1.9e-07 31.3 0.1 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD95074.1 - 0.0011 19.0 0.2 0.0044 17.0 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGD95074.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD95074.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_zinc_N PF00107.21 EGD95075.1 - 1.4e-21 76.4 0.0 2.4e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGD95075.1 - 3e-11 44.2 0.0 6.4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD95075.1 - 8.2e-08 31.9 0.0 2.6e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyridox_ox_2 PF12900.2 EGD95076.1 - 6e-38 129.8 0.0 8.7e-38 129.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SIR2 PF02146.12 EGD95077.1 - 4.5e-36 124.2 0.0 3.2e-35 121.4 0.0 1.9 1 1 0 1 1 1 1 Sir2 family MFS_1 PF07690.11 EGD95078.1 - 5.4e-38 130.6 20.4 8e-21 74.1 3.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGD95078.1 - 9.1e-10 37.5 19.6 0.0015 16.9 1.0 3.0 3 0 0 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 EGD95078.1 - 6.4e-07 28.3 20.9 2.3e-06 26.4 14.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 EGD95078.1 - 0.0014 18.3 7.3 0.0082 15.9 0.8 2.9 3 0 0 3 3 3 2 MFS_1 like family MFS_3 PF05977.8 EGD95078.1 - 0.73 7.8 19.1 0.012 13.7 3.3 2.5 3 0 0 3 3 3 0 Transmembrane secretion effector OATP PF03137.15 EGD95078.1 - 4.3 5.2 13.8 2.6 5.9 3.0 3.9 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3938 PF13074.1 EGD95078.1 - 7.9 6.3 8.2 8.5 6.2 0.2 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3938) MFS_1 PF07690.11 EGD95079.1 - 8.9e-25 87.1 55.6 3.5e-23 81.8 32.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.20 EGD95080.1 - 9.3e-50 169.5 0.0 1.9e-49 168.5 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Toxin_48 PF15528.1 EGD95080.1 - 0.049 13.5 0.1 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Putative toxin 48 SNF2_N PF00176.18 EGD95082.1 - 1e-74 251.0 0.0 4.1e-74 249.0 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD95082.1 - 9.3e-11 41.4 0.0 2.7e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 EGD95082.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 PP2C_C PF07830.8 EGD95082.1 - 0.025 14.6 0.8 1 9.5 0.0 3.0 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Pkinase PF00069.20 EGD95083.1 - 1.6e-62 211.0 0.0 1.8e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95083.1 - 1.4e-33 116.0 0.0 1.8e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD95083.1 - 3.9e-06 26.0 0.0 6.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD95083.1 - 0.0032 17.2 0.4 0.0076 16.0 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD95083.1 - 0.0092 15.0 0.4 0.02 13.9 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EGD95083.1 - 0.1 11.3 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cellulase PF00150.13 EGD95084.1 - 2.5e-09 36.7 2.8 8.3e-09 35.0 0.0 2.2 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF3377 PF11857.3 EGD95084.1 - 0.24 11.0 0.3 0.7 9.5 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Pox_A14 PF05767.7 EGD95084.1 - 0.25 11.3 0.3 0.45 10.5 0.2 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Shisa PF13908.1 EGD95085.1 - 0.00086 19.5 0.5 0.0013 18.9 0.3 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Sigma_reg_N PF13800.1 EGD95085.1 - 0.05 13.6 0.1 0.074 13.0 0.1 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal CD99L2 PF12301.3 EGD95085.1 - 0.068 12.8 0.2 0.068 12.8 0.1 1.9 1 1 0 2 2 2 0 CD99 antigen like protein 2 Neur_chan_memb PF02932.11 EGD95085.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Collagen PF01391.13 EGD95085.1 - 0.26 10.8 6.9 0.15 11.6 1.9 2.2 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) CENP-Q PF13094.1 EGD95088.1 - 3.3e-05 23.9 9.9 4.1e-05 23.6 6.9 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit HALZ PF02183.13 EGD95088.1 - 0.0012 18.4 10.6 0.23 11.1 0.4 3.1 2 1 0 2 2 2 2 Homeobox associated leucine zipper DivIC PF04977.10 EGD95088.1 - 0.0022 17.4 16.3 0.11 11.9 4.3 2.5 1 1 1 2 2 2 2 Septum formation initiator ERM PF00769.14 EGD95088.1 - 0.011 15.3 16.2 0.016 14.7 11.2 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF4201 PF13870.1 EGD95088.1 - 0.011 15.1 7.6 0.012 15.0 4.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) D5_N PF08706.6 EGD95088.1 - 0.016 15.3 1.9 0.023 14.8 1.3 1.2 1 0 0 1 1 1 0 D5 N terminal like Rootletin PF15035.1 EGD95088.1 - 0.029 14.3 10.0 0.04 13.8 6.9 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Filament PF00038.16 EGD95088.1 - 0.033 13.6 10.0 0.045 13.2 6.9 1.3 1 0 0 1 1 1 0 Intermediate filament protein RelA_SpoT PF04607.12 EGD95088.1 - 0.043 13.8 0.3 0.072 13.0 0.2 1.4 1 0 0 1 1 1 0 Region found in RelA / SpoT proteins MAD PF05557.8 EGD95088.1 - 0.098 10.7 10.7 0.12 10.4 7.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Phage_GP20 PF06810.6 EGD95088.1 - 0.14 11.5 15.5 1.3 8.4 10.7 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF904 PF06005.7 EGD95088.1 - 0.15 12.3 15.9 6.1e+02 0.7 10.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Frigida PF07899.6 EGD95088.1 - 0.16 10.6 6.5 0.25 10.0 4.5 1.3 1 0 0 1 1 1 0 Frigida-like protein Mnd1 PF03962.10 EGD95088.1 - 0.18 11.4 9.1 0.22 11.1 6.3 1.3 1 0 0 1 1 1 0 Mnd1 family Rabaptin PF03528.10 EGD95088.1 - 0.19 11.6 8.8 0.93 9.4 6.3 2.0 1 1 1 2 2 2 0 Rabaptin APG6 PF04111.7 EGD95088.1 - 0.23 10.4 10.5 0.29 10.1 7.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CALCOCO1 PF07888.6 EGD95088.1 - 0.33 9.1 8.4 0.38 8.9 5.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TSC22 PF01166.13 EGD95088.1 - 0.55 10.2 6.2 1.5 8.8 0.3 2.7 1 1 2 3 3 3 0 TSC-22/dip/bun family IncA PF04156.9 EGD95088.1 - 0.6 9.6 10.3 1.9 8.0 7.1 1.7 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 EGD95088.1 - 0.9 9.9 13.1 3.8 7.9 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Ax_dynein_light PF10211.4 EGD95088.1 - 1.9 8.2 10.1 3.6 7.3 7.0 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain bZIP_2 PF07716.10 EGD95088.1 - 3.7 7.4 14.6 3.1 7.6 1.3 3.2 1 1 3 4 4 4 0 Basic region leucine zipper DUF724 PF05266.9 EGD95088.1 - 5.3 6.6 11.0 8.4 5.9 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.1 EGD95088.1 - 7.5 5.4 10.1 12 4.7 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Shugoshin_N PF07558.6 EGD95088.1 - 7.5 6.3 7.2 16 5.3 0.1 3.2 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF3232 PF11554.3 EGD95090.1 - 0.037 13.9 0.6 0.06 13.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) DUF1098 PF06497.6 EGD95090.1 - 0.071 13.1 1.5 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) AF0941-like PF14591.1 EGD95090.1 - 0.095 12.7 1.9 0.096 12.7 0.2 1.8 2 0 0 2 2 2 0 AF0941-like Med13_C PF06333.7 EGD95091.1 - 9.3e-93 311.0 0.2 1.5e-92 310.3 0.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EGD95091.1 - 3.1e-24 85.4 0.0 3.1e-24 85.4 0.0 2.1 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal NPIP PF06409.6 EGD95091.1 - 0.036 12.8 0.9 0.064 11.9 0.6 1.3 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) NUC153 PF08159.7 EGD95092.1 - 7.5e-11 41.4 0.3 1.7e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EGD95092.1 - 2e-05 24.2 0.0 0.22 11.4 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Sulfotransfer_3 PF13469.1 EGD95093.1 - 0.0013 19.6 0.0 0.0024 18.8 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family Lipase3_N PF03893.11 EGD95093.1 - 0.092 12.5 0.1 3.7 7.4 0.0 2.7 3 0 0 3 3 3 0 Lipase 3 N-terminal region SET PF00856.23 EGD95094.1 - 7.2e-15 55.6 0.7 1e-13 51.9 0.0 3.0 2 2 0 2 2 2 1 SET domain TPR_11 PF13414.1 EGD95094.1 - 2.1e-10 40.0 3.8 7.8e-06 25.4 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGD95094.1 - 0.00066 19.4 4.9 0.035 14.0 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD95094.1 - 0.003 18.2 2.6 0.35 11.6 0.1 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGD95094.1 - 0.0063 16.2 1.5 1.2 9.0 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGD95094.1 - 0.0077 16.7 0.0 0.063 13.9 0.0 2.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGD95094.1 - 0.015 14.8 3.2 0.31 10.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGD95094.1 - 0.04 13.8 1.8 0.11 12.4 1.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat FAD_binding_4 PF01565.18 EGD95095.1 - 6.1e-27 93.7 0.5 1.3e-26 92.7 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD95095.1 - 2.9e-05 23.8 0.0 6.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF4483 PF14825.1 EGD95095.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) ATG13 PF10033.4 EGD95096.1 - 1.1e-66 224.5 0.0 1.8e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 RCC1 PF00415.13 EGD95098.1 - 8.1e-25 86.7 0.2 2.1e-06 27.8 0.0 5.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EGD95098.1 - 1.1e-13 51.1 0.2 4.5e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 EGD95098.1 - 2.1e-09 36.7 2.5 4.6e-08 32.4 0.0 3.9 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 EGD95098.1 - 1.4e-06 28.6 0.2 0.00054 20.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD95098.1 - 0.0086 16.2 0.1 0.44 10.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EGD95098.1 - 0.013 15.8 0.0 4 7.8 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD95098.1 - 0.013 15.6 0.0 0.42 10.9 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 EGD95098.1 - 0.06 13.1 0.1 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat TCO89 PF10452.4 EGD95099.1 - 0.027 13.3 0.4 0.027 13.3 0.2 3.5 2 2 0 2 2 2 0 TORC1 subunit TCO89 VHS PF00790.14 EGD95100.1 - 1.7e-42 144.4 3.1 6.5e-42 142.5 0.2 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EGD95100.1 - 3.2e-16 58.9 1.9 5.7e-16 58.1 1.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EGD95100.1 - 4.3e-05 22.7 8.9 0.0044 16.4 0.8 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-DHHC PF01529.15 EGD95100.1 - 0.015 14.6 0.1 0.039 13.3 0.1 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase FYVE_2 PF02318.11 EGD95100.1 - 0.056 13.3 0.3 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger OrfB_Zn_ribbon PF07282.6 EGD95100.1 - 2 8.1 4.8 2.6 7.7 2.4 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain UCH PF00443.24 EGD95101.1 - 1.3e-58 198.3 0.1 1.9e-58 197.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD95101.1 - 1.4e-25 90.3 0.0 3.4e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EGD95101.1 - 0.0012 19.1 0.0 0.0031 17.8 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain TPR_8 PF13181.1 EGD95101.1 - 0.17 11.6 0.1 0.48 10.3 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Rep_fac-A_C PF08646.5 EGD95101.1 - 7.2 6.3 5.7 18 5.0 1.4 2.8 2 1 1 3 3 3 0 Replication factor-A C terminal domain HSP70 PF00012.15 EGD95102.1 - 1.2e-263 875.5 13.0 1.4e-263 875.3 9.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGD95102.1 - 2.3e-19 69.1 0.8 4.6e-18 64.9 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EGD95102.1 - 0.00044 19.4 2.5 0.18 10.8 0.2 3.3 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase DDR PF08841.5 EGD95102.1 - 0.0041 15.9 0.9 0.036 12.9 0.2 2.3 2 1 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EGD95102.1 - 0.043 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EGD95102.1 - 4.5 7.1 9.1 4.9 7.0 0.1 4.1 3 1 0 3 3 3 0 Cell division protein FtsA GTP_EFTU PF00009.22 EGD95103.1 - 2.2e-51 173.9 0.0 3.9e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EGD95103.1 - 1e-19 70.4 9.6 2e-19 69.5 6.7 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 EGD95103.1 - 3.5e-08 33.5 0.0 9.1e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGD95103.1 - 6.2e-08 32.6 0.0 1.9e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGD95103.1 - 1.3e-07 31.6 0.0 4e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EGD95103.1 - 0.00012 21.4 0.1 0.028 13.6 0.0 2.4 1 1 1 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EGD95103.1 - 0.00048 20.6 0.0 0.002 18.6 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 EGD95103.1 - 0.00069 19.0 0.2 0.014 14.8 0.0 2.3 1 1 1 2 2 2 1 Ras family FeoB_N PF02421.13 EGD95103.1 - 0.00071 18.8 0.1 0.032 13.5 0.1 3.1 2 1 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EGD95103.1 - 0.0021 17.2 0.1 0.005 15.9 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGD95103.1 - 0.0024 17.0 0.1 0.34 10.1 0.0 2.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MobB PF03205.9 EGD95103.1 - 0.033 13.8 0.0 0.15 11.7 0.0 2.1 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Cyt-b5 PF00173.23 EGD95104.1 - 3.3e-26 90.8 0.0 4.2e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain K_trans PF02705.11 EGD95105.1 - 6.6e-182 605.5 17.3 7.7e-182 605.3 12.0 1.0 1 0 0 1 1 1 1 K+ potassium transporter VHS PF00790.14 EGD95106.1 - 1.4e-36 125.2 1.5 2.3e-36 124.5 1.0 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EGD95106.1 - 1.9e-17 62.3 0.1 1.1e-16 59.9 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EGD95106.1 - 2.8e-16 58.8 0.2 6.2e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGD95106.1 - 1.1e-13 50.4 0.1 2.9e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain UIM PF02809.15 EGD95106.1 - 0.024 14.1 0.9 0.062 12.9 0.6 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF4598 PF15370.1 EGD95106.1 - 0.055 13.7 1.0 0.16 12.2 0.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4598) HEAT_2 PF13646.1 EGD95106.1 - 0.081 13.2 1.3 0.35 11.1 0.3 2.3 2 0 0 2 2 2 0 HEAT repeats DUF775 PF05603.7 EGD95106.1 - 5 6.5 8.6 0.27 10.7 0.9 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF775) Pkinase PF00069.20 EGD95107.1 - 1.5e-64 217.6 0.1 2.8e-64 216.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95107.1 - 1.1e-42 145.9 0.8 1.5e-42 145.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EGD95107.1 - 1.5e-20 73.3 0.4 1.5e-20 73.3 0.3 2.8 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EGD95107.1 - 2.2e-06 26.8 0.0 3.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD95107.1 - 0.016 14.9 0.1 0.2 11.3 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.7 EGD95107.1 - 0.033 13.4 1.3 0.047 12.9 0.0 1.8 2 0 0 2 2 2 0 DSHCT (NUC185) domain Kdo PF06293.9 EGD95107.1 - 0.066 12.2 0.1 0.15 11.1 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KH_1 PF00013.24 EGD95108.1 - 2.4e-94 308.9 12.6 1.6e-12 46.8 0.1 13.3 14 0 0 14 14 14 9 KH domain KH_3 PF13014.1 EGD95108.1 - 5.6e-67 220.5 19.0 2.6e-08 33.3 0.1 12.7 14 0 0 14 14 14 10 KH domain SLS PF14611.1 EGD95108.1 - 3.1e-10 39.8 1.0 0.011 15.1 0.0 6.7 6 3 1 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 EGD95108.1 - 2e-09 36.8 21.0 0.0044 16.5 0.4 8.3 9 1 0 9 9 9 4 KH domain eIF3_N PF09440.5 EGD95108.1 - 0.11 12.6 0.9 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain KH_5 PF13184.1 EGD95108.1 - 0.57 10.0 10.4 12 5.7 0.1 5.9 7 0 0 7 7 7 0 NusA-like KH domain UCH_1 PF13423.1 EGD95109.1 - 9.5e-75 251.7 1.0 1.3e-74 251.3 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EGD95109.1 - 5.8e-19 68.9 0.0 3.7e-17 63.0 0.0 2.5 2 0 0 2 2 2 1 Exonuclease UCH PF00443.24 EGD95109.1 - 6.4e-05 22.1 0.0 0.00042 19.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3632 PF12311.3 EGD95110.1 - 2e-10 40.7 0.1 7.6e-07 29.1 0.0 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF3632) MSC PF09402.5 EGD95111.1 - 1.8e-93 312.9 0.0 2.5e-93 312.4 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EGD95111.1 - 2.4e-16 58.9 0.1 4.7e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain LRR_4 PF12799.2 EGD95112.1 - 2.1e-54 180.3 67.5 2e-09 36.8 1.5 13.0 9 2 5 14 14 14 11 Leucine Rich repeats (2 copies) PP2C PF00481.16 EGD95112.1 - 5e-54 183.3 0.0 7.1e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 EGD95112.1 - 4.8e-44 147.9 63.6 3.2e-11 42.7 5.0 10.6 5 3 7 12 12 12 10 Leucine rich repeat Guanylate_cyc PF00211.15 EGD95112.1 - 3e-27 95.1 0.0 7.1e-27 93.9 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EGD95112.1 - 4.6e-24 80.7 59.4 0.033 14.1 0.1 18.9 18 1 0 18 18 18 8 Leucine Rich Repeat LRR_7 PF13504.1 EGD95112.1 - 5.5e-11 40.7 60.5 0.55 10.6 0.2 16.7 17 0 0 17 17 16 5 Leucine rich repeat RA PF00788.18 EGD95112.1 - 1.1e-08 35.4 0.0 3.2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ad_cyc_g-alpha PF08509.6 EGD95112.1 - 1.5e-07 30.6 0.1 1.5e-07 30.6 0.1 3.0 4 0 0 4 4 3 1 Adenylate cyclase G-alpha binding domain LRR_5 PF13306.1 EGD95112.1 - 4.2e-06 26.5 4.8 0.03 14.0 0.2 4.0 3 1 1 4 4 4 2 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EGD95112.1 - 1e-05 25.0 56.2 2.1 8.7 0.1 15.9 20 0 0 20 20 17 4 Leucine Rich repeat LRR_9 PF14580.1 EGD95112.1 - 5.2e-05 22.8 10.9 0.21 11.1 0.0 4.3 2 1 1 4 4 4 3 Leucine-rich repeat tRNA-synt_1b PF00579.20 EGD95113.1 - 2.4e-65 220.5 0.0 3e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pkinase PF00069.20 EGD95116.1 - 4.4e-08 32.6 0.0 6.1e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95116.1 - 0.01 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.9 EGD95116.1 - 0.036 13.1 0.0 0.1 11.6 0.0 1.7 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGD95116.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_hydro_16 PF00722.16 EGD95117.1 - 1.7e-43 148.1 0.2 1.7e-43 148.1 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 EGD95118.1 - 3.1e-36 124.8 25.4 4.8e-36 124.2 17.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FctA PF12892.2 EGD95118.1 - 0.15 12.8 0.8 0.28 11.9 0.6 1.4 1 0 0 1 1 1 0 T surface-antigen of pili S4 PF01479.20 EGD95120.1 - 6.5e-11 41.4 0.0 1.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EGD95120.1 - 2.9e-05 24.3 2.2 4.3e-05 23.8 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain PilP PF04351.8 EGD95120.1 - 0.02 14.7 0.1 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein, PilP ADH_zinc_N PF00107.21 EGD95121.1 - 4.5e-08 32.6 0.0 8.3e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGD95121.1 - 0.025 15.4 0.0 0.059 14.2 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD95121.1 - 0.1 12.3 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DIPSY PF11763.3 EGD95122.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal Lsm_interact PF05391.6 EGD95123.1 - 0.014 14.7 0.4 0.029 13.7 0.3 1.5 1 0 0 1 1 1 0 Lsm interaction motif DnaJ PF00226.26 EGD95125.1 - 2.3e-23 81.7 2.3 3.6e-23 81.0 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGD95125.1 - 7.4e-15 54.7 16.9 1.3e-14 53.9 11.7 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EGD95125.1 - 1.6e-09 37.5 0.0 4.3e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 DnaJ C terminal domain HypA PF01155.14 EGD95125.1 - 0.21 11.2 6.4 1.1 8.9 0.3 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EGD95125.1 - 5.3 6.9 12.6 7.4 6.4 1.4 2.2 1 1 1 2 2 2 0 Double zinc ribbon DUF4449 PF14613.1 EGD95126.1 - 0.00066 19.6 0.1 0.00066 19.6 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) NAAA-beta PF15508.1 EGD95126.1 - 0.093 13.0 0.1 15 6.0 0.0 3.6 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Kinesin PF00225.18 EGD95127.1 - 1.5e-25 89.6 0.1 2.1e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain SAM_PNT PF02198.11 EGD95127.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Ish1 PF10281.4 EGD95127.1 - 0.09 12.8 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Malic_M PF03949.10 EGD95128.1 - 2.5e-86 289.3 0.0 3.4e-86 288.9 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EGD95128.1 - 2.4e-64 216.2 0.0 4e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PTR2 PF00854.16 EGD95129.1 - 3.3e-54 184.0 14.8 8.5e-54 182.7 10.2 1.7 1 1 0 1 1 1 1 POT family DUF2730 PF10805.3 EGD95129.1 - 0.14 11.9 0.0 0.41 10.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) THOC7 PF05615.8 EGD95130.1 - 7.9e-39 133.1 10.9 7.9e-39 133.1 7.6 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 SSFA2_C PF14723.1 EGD95130.1 - 0.013 15.2 3.9 0.025 14.3 2.7 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus CCDC92 PF14916.1 EGD95130.1 - 0.018 14.5 2.0 0.022 14.3 0.2 2.0 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DUF1843 PF08898.5 EGD95130.1 - 0.093 12.7 0.5 0.093 12.7 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) CDC37_N PF03234.9 EGD95130.1 - 0.52 10.6 9.4 1.1 9.5 6.5 1.6 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding zf-C4H2 PF10146.4 EGD95130.1 - 0.7 9.8 14.9 0.075 13.0 3.3 2.5 1 1 2 3 3 3 0 Zinc finger-containing protein FUSC PF04632.7 EGD95130.1 - 1.9 6.8 8.2 2.4 6.4 5.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bacillus_HBL PF05791.6 EGD95130.1 - 4 6.7 8.8 7 5.9 0.2 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TBCA PF02970.11 EGD95131.1 - 4.8e-20 71.4 10.9 2.4e-12 46.7 1.6 2.1 2 0 0 2 2 2 2 Tubulin binding cofactor A Dynamin_M PF01031.15 EGD95131.1 - 0.0034 16.1 0.2 0.0059 15.4 0.1 1.5 1 1 1 2 2 2 1 Dynamin central region Rhabdo_ncap PF00945.13 EGD95131.1 - 0.0077 14.8 0.1 0.01 14.4 0.1 1.1 1 0 0 1 1 1 1 Rhabdovirus nucleocapsid protein IncA PF04156.9 EGD95131.1 - 0.0092 15.5 4.5 0.011 15.2 3.1 1.1 1 0 0 1 1 1 1 IncA protein Spc24 PF08286.6 EGD95131.1 - 0.14 11.8 5.0 1.3 8.7 0.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 AAA_23 PF13476.1 EGD95131.1 - 0.15 12.3 3.4 0.21 11.8 2.3 1.3 1 0 0 1 1 1 0 AAA domain Uds1 PF15456.1 EGD95131.1 - 0.21 11.5 4.7 0.39 10.7 2.8 1.8 1 1 0 1 1 1 0 Up-regulated During Septation Mnd1 PF03962.10 EGD95131.1 - 0.3 10.7 7.8 0.97 9.0 1.2 2.1 2 0 0 2 2 2 0 Mnd1 family CP12 PF02672.10 EGD95131.1 - 2.8 8.4 5.6 5.1 7.6 0.2 2.4 2 0 0 2 2 2 0 CP12 domain TMF_DNA_bd PF12329.3 EGD95131.1 - 3.6 7.4 15.9 2 8.2 1.6 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4337 PF14235.1 EGD95131.1 - 4.1 7.2 8.9 1.4 8.7 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF2203 PF09969.4 EGD95131.1 - 9.5 6.4 6.6 6 7.1 1.2 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Band_7 PF01145.20 EGD95133.1 - 2.9e-16 59.8 0.0 2.9e-16 59.8 0.0 2.5 2 1 0 2 2 2 1 SPFH domain / Band 7 family Sugar_tr PF00083.19 EGD95134.1 - 6e-80 269.0 24.6 6.8e-80 268.8 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD95134.1 - 5.1e-16 58.3 34.3 2.1e-12 46.4 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGD95134.1 - 1.7e-09 36.6 25.3 5.8e-05 21.6 2.1 3.3 2 1 1 3 3 3 3 MFS/sugar transport protein EBP PF05241.7 EGD95134.1 - 1.1 8.2 11.1 0.077 11.9 3.3 2.0 2 0 0 2 2 2 0 Emopamil binding protein DUF3246 PF11596.3 EGD95135.1 - 0.013 14.8 7.0 0.017 14.4 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF4611 PF15387.1 EGD95135.1 - 0.12 12.5 2.8 0.19 11.9 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cyto_heme_lyase PF01265.12 EGD95135.1 - 0.3 10.6 6.4 0.66 9.5 4.4 1.6 1 1 0 1 1 1 0 Cytochrome c/c1 heme lyase F-box-like PF12937.2 EGD95136.1 - 0.014 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EGD95136.1 - 0.016 14.8 0.0 0.048 13.3 0.0 1.8 1 0 0 1 1 1 0 F-box domain Stc1 PF12898.2 EGD95136.1 - 0.076 13.0 2.0 0.14 12.2 0.4 2.1 2 0 0 2 2 2 0 Stc1 domain Elongin_A PF06881.6 EGD95137.1 - 8.2e-23 80.8 1.8 1.5e-22 80.0 1.2 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Sfi1 PF08457.5 EGD95138.1 - 2.3e-143 478.6 83.7 8.6e-142 473.4 53.3 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein DUF454 PF04304.8 EGD95138.1 - 0.018 15.0 0.4 2.8 8.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF454) p450 PF00067.17 EGD95139.1 - 2.9e-74 250.2 0.0 4.4e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EGD95139.1 - 1.2e-33 116.4 0.0 2.1e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGD95139.1 - 6.3e-20 71.6 0.0 1.4e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EGD95139.1 - 1.3e-13 51.4 0.0 2.9e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EGD95139.1 - 0.0005 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.7 EGD95139.1 - 0.2 11.5 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain tRNA-synt_1 PF00133.17 EGD95140.1 - 2e-219 729.5 0.0 2.9e-219 729.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGD95140.1 - 1e-24 87.0 0.0 3.2e-24 85.4 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGD95140.1 - 1.5e-17 63.3 0.1 1.9e-07 30.1 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) Uso1_p115_head PF04869.9 EGD95141.1 - 3.6e-111 370.8 0.0 2.6e-110 368.0 0.0 2.4 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EGD95141.1 - 8.2e-05 22.5 35.9 8.2e-05 22.5 24.9 3.7 2 1 2 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2570 PF10828.3 EGD95141.1 - 0.0088 15.6 7.3 0.0088 15.6 5.0 3.6 2 1 2 4 4 4 2 Protein of unknown function (DUF2570) Spc7 PF08317.6 EGD95141.1 - 3.5 6.2 41.4 0.083 11.5 5.5 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein XRN_N PF03159.13 EGD95142.1 - 1.8e-97 325.4 9.6 3.5e-66 222.9 0.0 3.6 4 0 0 4 4 4 2 XRN 5'-3' exonuclease N-terminus EPSP_synthase PF00275.15 EGD95143.1 - 1.5e-131 438.6 0.0 5.7e-131 436.7 0.0 1.8 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EGD95143.1 - 3.6e-96 321.0 0.0 6e-96 320.3 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EGD95143.1 - 1.1e-59 201.8 0.0 2.1e-59 200.8 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EGD95143.1 - 3.2e-36 124.5 0.3 6.2e-36 123.6 0.0 1.7 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EGD95143.1 - 1.3e-25 89.2 0.0 3.9e-25 87.7 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EGD95143.1 - 1.1e-11 44.9 0.0 3.4e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EGD95143.1 - 1.1e-08 34.6 0.0 3.3e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EGD95143.1 - 0.018 15.8 0.1 0.13 13.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGD95143.1 - 0.047 13.9 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGD95143.1 - 0.088 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PPR_2 PF13041.1 EGD95144.1 - 1.4e-24 85.8 0.0 7.2e-17 61.1 0.0 3.2 2 1 1 3 3 3 3 PPR repeat family PPR_1 PF12854.2 EGD95144.1 - 2.8e-08 33.0 0.1 0.019 14.4 0.0 3.6 3 0 0 3 3 3 3 PPR repeat PPR_3 PF13812.1 EGD95144.1 - 3.7e-08 33.0 0.4 0.00064 19.8 0.0 5.1 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 EGD95144.1 - 1.3e-05 24.8 5.7 4.8e-05 23.0 0.0 4.1 5 0 0 5 5 5 1 PPR repeat Bac_small_YrzI PF09501.5 EGD95144.1 - 1.5 8.7 5.9 8.2 6.4 0.1 2.9 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) DEAD PF00270.24 EGD95145.1 - 1.5e-45 154.7 0.0 2.8e-44 150.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGD95145.1 - 5.9e-05 22.9 0.0 0.00026 20.8 0.0 2.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF2443 PF10398.4 EGD95145.1 - 0.018 14.8 0.1 0.037 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) AAA_19 PF13245.1 EGD95145.1 - 0.028 14.1 0.2 1.5 8.6 0.2 2.5 2 1 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EGD95145.1 - 0.17 11.9 1.6 3.1 7.9 0.3 2.9 1 1 0 2 2 2 0 AAA domain Phos_pyr_kin PF08543.7 EGD95146.1 - 6.5e-62 208.9 0.3 1e-57 195.1 0.3 2.2 1 1 1 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EGD95146.1 - 1.8e-42 145.4 0.2 2.9e-42 144.8 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EGD95146.1 - 3.1e-05 23.2 0.0 5.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribosomal_60s PF00428.14 EGD95151.1 - 0.12 12.8 3.1 0.14 12.5 2.1 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Herpes_capsid PF06112.6 EGD95152.1 - 0.29 11.1 8.8 0.34 10.9 6.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Sds3 PF08598.6 EGD95154.1 - 3.9e-44 150.6 19.0 3.4e-43 147.5 13.1 2.0 1 1 0 1 1 1 1 Sds3-like RRF_GI PF12614.3 EGD95154.1 - 0.18 11.6 3.9 0.61 9.9 2.4 2.0 2 0 0 2 2 2 0 Ribosome recycling factor Collagen PF01391.13 EGD95156.1 - 9e-17 60.3 96.9 5.4e-10 38.6 32.2 5.1 4 2 1 5 5 5 2 Collagen triple helix repeat (20 copies) CFEM PF05730.6 EGD95156.1 - 7.9e-06 25.6 1.0 7.9e-06 25.6 0.7 2.5 2 0 0 2 2 2 1 CFEM domain Pro-rich PF15240.1 EGD95160.1 - 0.0016 18.6 2.0 0.0022 18.1 1.4 1.2 1 0 0 1 1 1 1 Proline-rich SRRM_C PF15230.1 EGD95160.1 - 6.6 6.8 10.3 1.1 9.4 0.2 2.5 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus PilO PF04350.8 EGD95161.1 - 0.0046 16.8 1.0 0.012 15.5 0.2 2.0 1 1 1 2 2 2 1 Pilus assembly protein, PilO Baculo_PEP_C PF04513.7 EGD95161.1 - 0.015 15.0 0.7 0.015 15.0 0.5 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2752 PF10825.3 EGD95161.1 - 0.068 13.2 1.6 0.12 12.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) RCC1 PF00415.13 EGD95162.1 - 1e-48 163.3 0.1 3.5e-09 36.7 0.0 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGD95162.1 - 5.6e-33 111.8 29.2 1.2e-07 31.0 0.6 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat p450 PF00067.17 EGD95163.1 - 7.5e-28 97.2 0.0 1.2e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Sterol_MT_C PF08498.5 EGD95164.1 - 6.4e-23 80.4 0.2 1e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EGD95164.1 - 7.7e-20 71.1 0.0 1.4e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD95164.1 - 6.4e-19 68.0 0.0 8.6e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD95164.1 - 3.5e-14 52.8 0.0 5.3e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD95164.1 - 8.7e-14 51.1 0.0 1.5e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGD95164.1 - 2.5e-13 50.5 0.0 5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGD95164.1 - 4.2e-13 48.9 0.0 5.7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EGD95164.1 - 1.8e-12 47.5 0.0 3.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD95164.1 - 7.1e-11 42.4 0.0 1.5e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD95164.1 - 3.4e-08 33.5 0.0 1.2e-07 31.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGD95164.1 - 1.1e-06 28.3 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EGD95164.1 - 0.00024 20.5 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EGD95164.1 - 0.001 18.6 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 EGD95164.1 - 0.0014 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EGD95164.1 - 0.0043 16.4 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.6 EGD95164.1 - 0.011 15.2 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_24 PF13578.1 EGD95164.1 - 0.021 15.6 0.0 0.051 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EGD95164.1 - 0.051 12.5 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase BTB PF00651.26 EGD95165.1 - 3.6e-06 26.9 0.0 9.4e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_S24 PF00717.18 EGD95166.1 - 7.7e-08 31.8 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Macoilin PF09726.4 EGD95168.1 - 0.13 10.5 11.6 0.15 10.2 8.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Phage_tail PF04630.7 EGD95168.1 - 0.31 10.0 3.9 0.44 9.6 2.7 1.2 1 0 0 1 1 1 0 Phage major tail protein UQ_con PF00179.21 EGD95169.1 - 3.5e-41 139.8 0.0 4e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD95169.1 - 1.2e-07 31.4 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGD95169.1 - 0.031 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 EGD95169.1 - 0.063 13.1 0.2 0.099 12.5 0.1 1.5 1 1 0 1 1 1 0 RWD domain Acyl_transf_3 PF01757.17 EGD95170.1 - 3.3e-08 32.7 28.5 2.9e-06 26.3 0.4 3.0 1 1 2 3 3 3 2 Acyltransferase family CAP_N PF01213.14 EGD95171.1 - 8.5 5.5 11.8 10 5.3 8.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RabGAP-TBC PF00566.13 EGD95172.1 - 2.5e-36 125.1 0.4 4.4e-35 121.1 0.1 2.6 2 1 0 2 2 2 1 Rab-GTPase-TBC domain PAT1 PF09770.4 EGD95172.1 - 0.49 8.5 13.9 0.69 8.0 9.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BCS1_N PF08740.6 EGD95174.1 - 3.2e-54 183.3 0.4 4.3e-54 182.9 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGD95174.1 - 4e-13 49.7 0.0 2.4e-05 24.5 0.0 2.5 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGD95174.1 - 7e-05 22.8 0.0 0.00026 21.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EGD95174.1 - 0.00014 22.7 0.0 0.00033 21.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGD95174.1 - 0.00023 21.0 0.0 0.00076 19.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGD95174.1 - 0.0003 21.1 0.0 0.15 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGD95174.1 - 0.00059 19.9 0.0 0.0061 16.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EGD95174.1 - 0.0078 16.3 0.0 0.027 14.6 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_19 PF13245.1 EGD95174.1 - 0.0097 15.6 0.4 0.051 13.3 0.0 2.5 2 1 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EGD95174.1 - 0.01 15.2 0.0 0.038 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGD95174.1 - 0.017 14.6 0.0 0.054 13.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EGD95174.1 - 0.034 13.8 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EGD95174.1 - 0.041 12.8 0.0 0.29 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_11 PF13086.1 EGD95174.1 - 0.045 13.3 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGD95174.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 EGD95174.1 - 0.055 12.5 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF2735 PF10931.3 EGD95174.1 - 0.075 13.2 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) Miro PF08477.8 EGD95174.1 - 0.098 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Zeta_toxin PF06414.7 EGD95174.1 - 0.11 11.5 0.0 0.35 9.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.10 EGD95174.1 - 0.11 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 EGD95174.1 - 0.12 11.5 0.0 0.55 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Lactamase_B_2 PF12706.2 EGD95175.1 - 9e-12 44.9 0.0 4e-11 42.8 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGD95175.1 - 3.2e-08 33.4 0.0 7.6e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Cpn60_TCP1 PF00118.19 EGD95176.1 - 7.8e-163 542.5 0.7 8.9e-163 542.3 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-PARP PF00645.13 EGD95177.1 - 3.8e-21 75.1 0.2 3.8e-21 75.1 0.2 2.3 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Kinesin PF00225.18 EGD95178.1 - 7.9e-23 80.6 0.0 1.3e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.10 EGD95178.1 - 0.00017 21.3 0.4 0.00053 19.7 0.3 1.9 1 0 0 1 1 1 1 Basic region leucine zipper Herpes_UL6 PF01763.11 EGD95178.1 - 0.15 10.1 0.8 0.22 9.6 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like TPR_14 PF13428.1 EGD95179.1 - 0.06 14.0 2.5 16 6.4 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Daxx PF03344.10 EGD95179.1 - 3.3 6.0 74.4 0.18 10.2 31.8 2.2 2 0 0 2 2 2 0 Daxx Family ChAPs PF09295.5 EGD95180.1 - 1.1e-154 515.0 0.0 1.5e-154 514.5 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EGD95180.1 - 0.00018 21.0 0.1 0.042 13.4 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.1 EGD95180.1 - 0.00032 21.0 1.4 4.7 8.1 0.0 4.5 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGD95180.1 - 0.00041 20.0 0.1 0.81 9.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGD95180.1 - 0.00046 19.6 0.2 6.3 6.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EGD95180.1 - 0.00063 19.8 0.0 0.11 12.6 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGD95180.1 - 0.0024 17.6 0.4 0.82 9.5 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGD95180.1 - 0.042 13.7 0.6 3.1 7.8 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGD95180.1 - 0.069 13.4 0.0 5.6 7.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat CDC45 PF02724.9 EGD95180.1 - 0.11 10.4 5.2 0.16 9.9 3.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 EGD95180.1 - 0.12 11.9 5.2 0.46 10.0 3.3 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Daxx PF03344.10 EGD95180.1 - 0.83 8.0 11.1 1.2 7.5 7.7 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EGD95180.1 - 1.9 6.2 9.9 2.9 5.7 6.9 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EGD95180.1 - 7.9 5.0 15.2 12 4.4 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Exo5 PF09810.4 EGD95182.1 - 6.6e-91 304.8 0.0 1.4e-90 303.7 0.0 1.5 2 0 0 2 2 2 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EGD95182.1 - 0.0056 16.0 1.6 0.28 10.5 0.0 2.8 2 2 0 2 2 2 2 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.7 EGD95183.1 - 1.5e-15 56.6 1.2 1.5e-15 56.6 0.9 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Oxidored_q4 PF00507.14 EGD95183.1 - 0.0045 16.7 0.1 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Histone PF00125.19 EGD95184.1 - 3.3e-30 103.9 0.5 5.4e-30 103.3 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGD95184.1 - 2.7e-06 27.4 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EGD95184.1 - 0.0059 16.3 0.1 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.18 EGD95184.1 - 0.0081 16.2 0.2 0.026 14.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGD95185.1 - 2e-15 56.6 0.1 2.4e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EGD95185.1 - 0.00015 21.6 0.1 0.00021 21.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EGD95185.1 - 0.00015 21.8 0.1 0.00022 21.3 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGD95185.1 - 0.00049 20.1 0.1 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGD95185.1 - 0.033 13.9 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EGD95185.1 - 0.065 12.4 0.0 0.067 12.4 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EGD95185.1 - 0.15 11.8 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-C2H2 PF00096.21 EGD95188.1 - 6.4e-05 23.0 32.0 0.00035 20.7 0.9 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD95188.1 - 0.0027 17.9 1.3 0.0027 17.9 0.9 4.7 5 0 0 5 5 5 3 C2H2-type zinc finger Glyco_transf_22 PF03901.12 EGD95189.1 - 3.7e-87 293.0 15.7 4.3e-87 292.8 10.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HET PF06985.6 EGD95190.1 - 2.2e-09 37.5 0.0 4.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Gar1 PF04410.9 EGD95191.1 - 4.9e-45 152.7 0.2 4.9e-45 152.7 0.1 2.2 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region RRM_1 PF00076.17 EGD95193.1 - 3.1e-05 23.5 0.0 5.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD95193.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD95193.1 - 0.044 13.6 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_28 PF02636.12 EGD95194.1 - 5.1e-79 265.2 0.0 6.7e-79 264.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rhodanese PF00581.15 EGD95195.1 - 1.2e-10 41.6 0.0 1.5e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_S21 PF01165.15 EGD95196.1 - 7.1e-08 31.7 0.4 1.8e-07 30.5 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S21 PGI PF00342.14 EGD95198.1 - 7.2e-220 730.4 1.9 8.3e-220 730.2 1.3 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Urease_beta PF00699.15 EGD95198.1 - 0.024 14.4 0.1 0.051 13.4 0.1 1.5 1 0 0 1 1 1 0 Urease beta subunit PWI PF01480.12 EGD95201.1 - 7.1e-12 45.2 0.4 2.4e-11 43.5 0.3 2.0 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EGD95201.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_5 PF00266.14 EGD95202.1 - 1.2e-27 96.6 0.0 2e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MR_MLE_C PF13378.1 EGD95203.1 - 1.1e-18 67.2 0.0 3e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EGD95203.1 - 4.4e-14 52.7 0.1 1e-12 48.3 0.0 2.6 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EGD95203.1 - 2.5e-07 30.6 0.1 5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 EGD95203.1 - 0.0067 15.3 0.0 0.019 13.9 0.0 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus TIM21 PF08294.6 EGD95204.1 - 2.8e-39 134.0 0.0 3.5e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EGD95204.1 - 7.9e-07 28.5 0.0 1.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 HIG_1_N PF04588.8 EGD95204.1 - 0.019 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Hypoxia induced protein conserved region ArfGap PF01412.13 EGD95205.1 - 1.4e-35 121.5 0.5 2.5e-35 120.8 0.4 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pterin_bind PF00809.17 EGD95206.1 - 2.1e-65 220.0 0.0 3.7e-65 219.2 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EGD95206.1 - 1.3e-38 131.5 0.0 2.2e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) KdpC PF02669.10 EGD95206.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 K+-transporting ATPase, c chain NMO PF03060.10 EGD95207.1 - 2.5e-71 240.5 1.4 3e-71 240.2 1.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGD95207.1 - 5.2e-08 32.1 0.1 3.9e-07 29.2 0.1 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGD95207.1 - 2.1e-07 30.0 1.7 3.5e-07 29.3 1.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EGD95207.1 - 0.0007 18.6 0.3 0.0011 17.9 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EGD95207.1 - 0.0043 16.0 0.2 0.0067 15.3 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase eIF3g PF12353.3 EGD95208.1 - 2.3e-47 160.1 1.4 4.1e-47 159.2 1.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EGD95208.1 - 1.6e-17 62.8 0.2 2.7e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD95208.1 - 6.4e-13 48.4 0.1 1e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD95208.1 - 7.2e-07 28.9 0.1 1.3e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDT80_PhoG PF05224.7 EGD95211.1 - 2.9e-41 141.5 0.0 4.3e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family ELL PF10390.4 EGD95211.1 - 0.033 13.4 0.3 0.08 12.1 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL PHO4 PF01384.15 EGD95212.1 - 1.6e-76 257.0 10.0 2e-76 256.7 6.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family MFS_1 PF07690.11 EGD95213.1 - 3.4e-11 42.4 57.2 8.5e-08 31.2 12.6 2.7 2 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD95213.1 - 0.00029 19.5 11.9 0.00029 19.5 8.3 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter NRDE PF05742.7 EGD95214.1 - 8e-44 149.9 0.0 1.4e-43 149.1 0.0 1.4 1 1 0 1 1 1 1 NRDE protein BPL_N PF09825.4 EGD95215.1 - 3.1e-136 453.9 0.0 6.4e-136 452.9 0.0 1.5 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EGD95215.1 - 3.3e-15 56.2 0.0 7.4e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EGD95215.1 - 0.0001 21.8 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain CHCH PF06747.8 EGD95216.1 - 2.6e-06 27.1 4.6 3.3e-06 26.8 3.2 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EGD95216.1 - 0.012 15.3 2.1 0.017 14.8 1.2 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Toxin_25 PF08095.6 EGD95216.1 - 0.056 13.1 0.3 0.056 13.1 0.2 2.2 2 1 0 2 2 2 0 Hefutoxin family COX17 PF05051.8 EGD95216.1 - 0.14 12.2 0.3 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Mgm101p PF06420.7 EGD95217.1 - 5.7e-92 305.7 0.0 6.5e-92 305.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 eIF-1a PF01176.14 EGD95217.1 - 0.071 12.5 0.2 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 zf-RING_2 PF13639.1 EGD95218.1 - 1.2e-14 53.8 5.9 1.9e-14 53.2 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGD95218.1 - 5.9e-08 32.2 2.1 9.6e-08 31.5 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD95218.1 - 1.2e-07 31.5 4.5 2e-07 30.9 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD95218.1 - 1.9e-07 31.0 0.6 3.7e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGD95218.1 - 1.8e-06 27.5 2.0 3.3e-06 26.6 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD95218.1 - 3.8e-06 26.5 2.0 6.3e-06 25.8 1.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGD95218.1 - 0.00036 20.3 1.5 0.00072 19.3 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGD95218.1 - 0.004 16.6 2.3 0.0077 15.7 1.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.24 EGD95218.1 - 0.52 10.0 2.6 1.1 9.0 1.8 1.6 1 0 0 1 1 1 0 PHD-finger TMEM154 PF15102.1 EGD95218.1 - 0.53 9.9 0.0 0.53 9.9 0.0 2.6 3 0 0 3 3 3 0 TMEM154 protein family Prok-RING_1 PF14446.1 EGD95218.1 - 0.58 9.9 2.7 4 7.2 2.2 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 EGD95218.1 - 0.89 9.4 5.2 1.7 8.5 3.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EGD95218.1 - 2 8.4 6.4 3 7.8 2.6 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_3 PF14369.1 EGD95218.1 - 3.1 7.8 5.6 1.3 9.1 0.1 2.7 2 0 0 2 2 2 0 zinc-finger NLPC_P60 PF00877.14 EGD95219.1 - 0.0013 18.4 0.2 0.0021 17.8 0.1 1.3 1 0 0 1 1 1 1 NlpC/P60 family Paramecium_SA PF01508.11 EGD95219.1 - 3.9 7.7 12.2 15 5.9 8.5 2.0 1 1 0 1 1 1 0 Paramecium surface antigen domain Phage_lysozyme PF00959.14 EGD95220.1 - 2.7e-14 53.3 0.0 3.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme FAD_binding_2 PF00890.19 EGD95220.1 - 0.11 11.3 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Stanniocalcin PF03298.8 EGD95221.1 - 0.032 13.2 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Stanniocalcin family MS_channel PF00924.13 EGD95222.1 - 4.1e-19 68.7 0.4 9e-19 67.6 0.3 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EGD95222.1 - 0.035 13.4 0.3 0.11 11.7 0.2 2.0 1 0 0 1 1 1 0 EF hand Aminotran_1_2 PF00155.16 EGD95227.1 - 5.3e-77 259.2 0.0 6.1e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Chlorophyllase2 PF12740.2 EGD95228.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Syntaxin-18_N PF10496.4 EGD95229.1 - 4.5e-11 42.4 0.7 1.3e-10 40.9 0.1 2.1 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EGD95229.1 - 7e-06 25.6 1.5 3.5e-05 23.4 0.5 2.4 2 0 0 2 2 2 1 SNARE domain TPR_1 PF00515.23 EGD95230.1 - 6.7e-14 50.8 7.3 2.4e-07 30.0 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGD95230.1 - 2e-13 49.1 5.9 1.3e-05 24.6 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGD95230.1 - 5.2e-12 45.2 6.2 5.5e-10 38.7 0.3 3.2 3 0 0 3 3 3 2 TPR repeat PB1 PF00564.19 EGD95230.1 - 2.7e-08 33.3 0.1 5.3e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.1 EGD95230.1 - 4.2e-08 32.9 1.1 3.5e-05 23.6 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGD95230.1 - 6.8e-08 31.7 2.0 0.0033 17.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD95230.1 - 8.8e-07 28.2 1.1 3.1e-05 23.4 0.1 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGD95230.1 - 1.3e-05 25.2 0.2 2.2 8.8 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGD95230.1 - 4.2e-05 23.4 1.2 0.0025 17.8 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD95230.1 - 4.7e-05 23.9 2.0 0.0036 17.9 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGD95230.1 - 0.00033 20.4 0.2 1.1 9.2 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD95230.1 - 0.0038 17.7 3.7 0.077 13.6 0.0 3.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_5 PF12688.2 EGD95230.1 - 0.054 13.5 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Tetratrico peptide repeat Apc3 PF12895.2 EGD95230.1 - 0.082 13.0 3.5 0.17 12.0 0.1 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sod_Cu PF00080.15 EGD95231.1 - 8.4e-14 51.9 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EGD95231.1 - 1.7e-11 44.1 0.0 3.2e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Pkinase PF00069.20 EGD95232.1 - 4.6e-62 209.5 0.0 8.6e-62 208.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95232.1 - 2.6e-26 92.2 0.0 4.5e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD95232.1 - 0.01 14.8 0.0 0.01 14.8 0.0 1.6 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EGD95232.1 - 2.6 7.7 6.4 8 6.1 4.4 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Bd3614_N PF14442.1 EGD95233.1 - 0.17 11.8 5.2 0.54 10.2 3.6 2.0 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal RXT2_N PF08595.6 EGD95233.1 - 3.4 7.4 12.9 6.9 6.4 3.9 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal AMP-binding PF00501.23 EGD95234.1 - 2.5e-244 810.1 0.0 1.3e-84 284.0 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EGD95234.1 - 1.3e-127 424.8 0.0 4.7e-45 153.7 0.0 4.5 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.20 EGD95234.1 - 1.4e-36 124.5 2.8 1.1e-10 41.6 0.0 4.3 4 0 0 4 4 4 3 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 EGD95234.1 - 1.8e-36 125.3 0.0 3.6e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.1 EGD95234.1 - 1.3e-15 58.0 0.0 0.00011 23.0 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EGD95234.1 - 3.1e-09 36.6 0.0 8.6e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AATase PF07247.7 EGD95234.1 - 0.00074 18.1 0.1 7.3 5.0 0.0 5.0 3 3 0 3 3 3 1 Alcohol acetyltransferase 3Beta_HSD PF01073.14 EGD95234.1 - 0.15 10.7 0.0 0.29 9.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Usp PF00582.21 EGD95235.1 - 4.2e-20 72.3 0.1 9.4e-20 71.2 0.1 1.6 1 0 0 1 1 1 1 Universal stress protein family Med27 PF11571.3 EGD95236.1 - 4.2e-19 68.4 0.9 1.2e-18 66.9 0.3 2.0 2 0 0 2 2 2 1 Mediator complex subunit 27 Transposase_mut PF00872.13 EGD95236.1 - 0.068 11.7 0.0 1.2 7.6 0.0 2.0 1 1 1 2 2 2 0 Transposase, Mutator family DUF1510 PF07423.6 EGD95237.1 - 0.0074 15.6 2.4 0.011 15.1 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 EGD95237.1 - 0.11 12.0 3.8 0.18 11.2 2.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF3827 PF12877.2 EGD95237.1 - 1.1 7.2 5.8 1.4 6.8 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SNF2_N PF00176.18 EGD95238.1 - 1.2e-71 240.9 0.0 2e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD95238.1 - 4.2e-14 52.1 0.0 1e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGD95238.1 - 2.4e-06 26.5 0.0 7.3e-06 25.0 0.0 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Pkinase PF00069.20 EGD95240.1 - 3.2e-51 173.9 0.0 1.1e-50 172.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95240.1 - 2.6e-23 82.4 0.0 8e-23 80.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGD95240.1 - 0.00058 19.6 0.1 0.00058 19.6 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGD95240.1 - 0.0034 16.7 0.1 0.011 15.0 0.1 1.8 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 EGD95240.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) eIF-3c_N PF05470.7 EGD95241.1 - 7.4e-171 569.2 25.9 2.8e-137 458.3 1.8 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EGD95241.1 - 2.4e-13 50.3 3.4 3.3e-12 46.6 0.1 3.7 2 2 1 3 3 3 1 PCI domain Daxx PF03344.10 EGD95241.1 - 9.2 4.6 25.2 16 3.8 17.5 1.3 1 0 0 1 1 1 0 Daxx Family EAP30 PF04157.11 EGD95242.1 - 2.5e-56 190.3 0.0 3.1e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.2 EGD95242.1 - 0.097 12.3 0.4 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 MarR family Ribosomal_L30_N PF08079.7 EGD95243.1 - 9.3e-25 86.4 15.2 1.7e-24 85.6 10.6 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EGD95243.1 - 2e-18 65.7 2.7 3e-18 65.1 1.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_pol_B PF00136.16 EGD95244.1 - 2.4e-114 382.6 0.9 3.8e-114 382.0 0.6 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EGD95244.1 - 2e-66 222.9 1.3 2.8e-66 222.4 0.1 1.9 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EGD95244.1 - 5.3e-44 150.4 0.2 1.2e-43 149.2 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EGD95244.1 - 3.4e-25 87.6 11.0 3.4e-25 87.6 7.7 2.4 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal HSP70 PF00012.15 EGD95245.1 - 1.6e-262 871.8 16.0 1.8e-262 871.6 11.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGD95245.1 - 1.2e-14 53.6 6.2 8.7e-13 47.5 1.5 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EGD95245.1 - 0.00014 21.5 0.1 0.00037 20.1 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EGD95245.1 - 0.021 14.6 11.5 1.3 8.8 1.5 4.6 2 2 2 4 4 4 0 Cell division protein FtsA Hydantoinase_A PF01968.13 EGD95245.1 - 0.032 13.3 3.3 1.8 7.5 0.0 3.3 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DUF2415 PF10313.4 EGD95246.1 - 4.9e-16 58.1 0.0 1.3e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EGD95246.1 - 0.023 14.5 0.7 7.2 6.6 0.3 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF1646 PF07854.7 EGD95247.1 - 0.024 13.7 4.0 0.072 12.2 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1646) DSHCT PF08148.7 EGD95248.1 - 1.2e-60 203.8 0.7 2.1e-60 203.0 0.5 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EGD95248.1 - 9.2e-19 67.5 0.0 1.9e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD95248.1 - 2e-06 27.5 0.0 4.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD95248.1 - 0.11 12.3 0.0 1.8 8.3 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit BRCA2 PF00634.13 EGD95248.1 - 0.15 11.3 2.8 0.23 10.7 0.1 2.5 2 0 0 2 2 2 0 BRCA2 repeat IBN_N PF03810.14 EGD95249.1 - 1.5e-15 56.8 1.7 5.4e-13 48.6 0.0 5.1 6 0 0 6 6 6 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EGD95249.1 - 1.7e-07 31.4 0.0 0.0061 16.8 0.0 3.0 2 0 0 2 2 2 2 HEAT repeats Cse1 PF08506.5 EGD95249.1 - 7.6e-07 28.0 0.0 1.8e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 EGD95249.1 - 0.0001 22.2 2.2 0.0065 16.3 0.0 4.0 3 1 0 3 3 3 1 Exportin 1-like protein DUF2435 PF10363.4 EGD95249.1 - 0.0018 18.1 0.2 0.0094 15.8 0.1 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) GRIP PF01465.15 EGD95249.1 - 0.047 13.2 0.4 0.72 9.4 0.0 3.3 2 1 1 3 3 3 0 GRIP domain Vac14_Fab1_bd PF12755.2 EGD95249.1 - 0.053 13.9 0.2 1.4 9.3 0.0 3.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGD95249.1 - 0.066 13.7 2.3 1.6 9.3 0.0 4.4 5 0 0 5 5 5 0 HEAT-like repeat HEAT PF02985.17 EGD95249.1 - 0.15 12.2 0.5 2.7 8.2 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat RRM_1 PF00076.17 EGD95250.1 - 1.3e-08 34.2 0.0 3.1e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD95250.1 - 1.9e-07 30.9 0.0 3.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD95250.1 - 0.00063 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CENP-F_N PF10481.4 EGD95251.1 - 0.018 14.3 0.5 0.018 14.3 0.3 2.1 2 0 0 2 2 2 0 Cenp-F N-terminal domain PV-1 PF06637.6 EGD95251.1 - 0.13 10.8 3.7 0.086 11.3 0.8 1.8 2 0 0 2 2 2 0 PV-1 protein (PLVAP) BLVR PF06375.6 EGD95252.1 - 0.0079 16.0 14.0 0.0079 16.0 9.7 2.7 2 1 0 2 2 2 1 Bovine leukaemia virus receptor (BLVR) DbpA PF03880.10 EGD95253.1 - 0.002 17.7 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_5 PF13893.1 EGD95253.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAPS PF04499.10 EGD95253.1 - 5.7 5.4 7.4 8.7 4.8 5.1 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MFS_1 PF07690.11 EGD95255.1 - 6.2e-33 113.9 25.8 4.7e-32 111.0 7.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD95255.1 - 2.5e-09 36.2 7.7 2.5e-09 36.2 5.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Folate_carrier PF01770.13 EGD95255.1 - 0.063 11.7 4.4 0.27 9.6 0.2 2.2 2 0 0 2 2 2 0 Reduced folate carrier Kinetocho_Slk19 PF12709.2 EGD95256.1 - 4.4e-21 74.7 28.6 6.4e-21 74.2 4.3 4.5 3 1 2 5 5 5 2 Central kinetochore-associated IncA PF04156.9 EGD95256.1 - 0.0047 16.5 23.7 0.15 11.6 4.0 2.6 2 0 0 2 2 2 2 IncA protein WEMBL PF05701.6 EGD95256.1 - 1.4 7.3 43.2 4.1 5.7 29.9 1.7 1 1 0 1 1 1 0 Weak chloroplast movement under blue light GAS PF13851.1 EGD95256.1 - 1.8 7.6 29.6 3.4 6.8 8.2 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EGD95256.1 - 2.5 7.9 42.3 0.067 13.0 8.7 3.3 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EGD95256.1 - 4.2 7.1 18.2 0.19 11.5 3.6 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 EGD95256.1 - 5 5.4 24.9 0.47 8.8 5.1 2.5 1 1 0 2 2 2 0 AAA domain FAD_binding_3 PF01494.14 EGD95257.1 - 1.2e-11 44.2 0.1 4.3e-11 42.4 0.0 1.9 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EGD95257.1 - 9.7e-05 22.3 0.2 0.012 15.6 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGD95257.1 - 0.0001 21.3 0.6 0.075 11.9 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 EGD95257.1 - 0.00037 19.5 0.1 0.00085 18.3 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGD95257.1 - 0.0065 16.2 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 EGD95257.1 - 0.054 12.3 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Herpes_capsid PF06112.6 EGD95258.1 - 3.1 7.8 6.3 1.1 9.3 2.6 1.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Fungal_trans PF04082.13 EGD95259.1 - 4e-36 124.2 0.5 6.2e-36 123.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EGD95260.1 - 2.1e-06 26.6 22.1 3.4e-06 26.0 12.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EGD95260.1 - 0.00063 19.2 4.6 0.034 13.6 3.1 2.7 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 Ni_hydr_CYTB PF01292.15 EGD95260.1 - 0.12 11.7 6.6 0.24 10.7 4.6 1.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Amidohydro_4 PF13147.1 EGD95261.1 - 3.7e-13 50.1 0.2 2.4e-12 47.4 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGD95261.1 - 2.4e-12 47.1 0.0 1.7e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EGD95261.1 - 1.4e-07 31.0 0.1 3.5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGD95261.1 - 8.1e-07 28.7 0.1 9.9e-06 25.2 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase GMC_oxred_C PF05199.8 EGD95262.1 - 5.1e-38 130.6 0.0 7.1e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EGD95262.1 - 3.6e-36 124.8 0.0 6.9e-19 68.0 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase DAO PF01266.19 EGD95262.1 - 3.2e-05 22.9 0.1 0.0002 20.3 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD95262.1 - 7.5e-05 22.6 0.1 0.00026 20.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGD95262.1 - 7.8e-05 21.7 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EGD95262.1 - 0.0097 14.5 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EGD95262.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGD95262.1 - 0.051 12.4 0.0 0.089 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Aldedh PF00171.17 EGD95263.1 - 1.7e-160 534.4 0.4 2e-160 534.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glucosamine_iso PF01182.15 EGD95264.1 - 1.3e-25 90.3 0.0 1.9e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.16 EGD95265.1 - 8e-60 202.3 0.0 1.4e-59 201.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGD95265.1 - 1.2e-07 31.5 0.1 4e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 EGD95265.1 - 7.1e-06 25.9 0.0 2.5e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD95265.1 - 0.0059 16.7 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD95265.1 - 0.018 14.7 0.0 0.091 12.5 0.0 2.2 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 EGD95265.1 - 0.031 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.7 EGD95266.1 - 6.5e-33 114.2 3.2 7.6e-33 114.0 0.0 2.5 3 0 0 3 3 3 1 NDT80 / PhoG like DNA-binding family Hexokinase_1 PF00349.16 EGD95267.1 - 1.3e-34 119.3 0.0 2.1e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EGD95267.1 - 3.2e-31 108.4 0.0 7.9e-25 87.4 0.0 2.4 2 0 0 2 2 2 2 Hexokinase AATF-Che1 PF13339.1 EGD95267.1 - 0.036 14.2 1.7 0.086 12.9 1.2 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor p450 PF00067.17 EGD95268.1 - 2.5e-58 197.7 0.0 3.1e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Hep_59 PF07052.6 EGD95269.1 - 6.4e-23 81.1 0.1 6.4e-23 81.1 0.1 2.6 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 CRT10 PF08728.5 EGD95272.1 - 0.0012 17.0 1.0 0.0013 16.8 0.7 1.0 1 0 0 1 1 1 1 CRT10 RNA_pol_3_Rpc31 PF11705.3 EGD95272.1 - 6.2 6.6 8.1 10 5.9 5.5 1.4 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TRP PF06011.7 EGD95273.1 - 7.7e-130 433.3 8.5 1e-129 432.9 5.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGD95273.1 - 5.7e-31 107.4 0.3 9e-31 106.8 0.2 1.3 1 0 0 1 1 1 1 ML-like domain DUF3154 PF11351.3 EGD95273.1 - 0.024 14.4 1.9 1.7 8.3 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3154) IncA PF04156.9 EGD95273.1 - 1.1 8.8 11.7 4.9 6.6 0.0 3.2 3 0 0 3 3 3 0 IncA protein TFIIIC_sub6 PF10419.4 EGD95274.1 - 9.3e-05 21.8 0.2 0.00018 20.8 0.1 1.5 1 0 0 1 1 1 1 TFIIIC subunit Hyphal_reg_CWP PF11765.3 EGD95276.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal MFS_1 PF07690.11 EGD95278.1 - 3.5e-50 170.6 47.0 2.3e-45 154.8 33.9 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGD95278.1 - 1.7e-10 39.7 10.1 1.7e-10 39.7 7.0 2.3 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PET PF06297.9 EGD95279.1 - 0.066 12.8 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 PET Domain Myb_DNA-bind_6 PF13921.1 EGD95280.1 - 7.5e-31 106.0 4.1 2.1e-14 53.3 1.2 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD95280.1 - 4.1e-28 97.1 6.6 1.4e-09 37.8 0.3 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EGD95280.1 - 0.05 13.4 3.5 6.9 6.6 2.3 2.7 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.4 EGD95280.1 - 0.085 13.0 2.4 6.6 7.0 0.1 3.3 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PPR_3 PF13812.1 EGD95281.1 - 8.1e-16 56.9 0.6 3.8e-05 23.6 0.0 8.5 10 0 0 10 10 10 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGD95281.1 - 8.8e-13 48.0 0.8 0.0054 16.6 0.0 7.0 7 1 1 8 8 8 3 PPR repeat family PPR PF01535.15 EGD95281.1 - 9.4e-08 31.5 4.4 0.67 10.0 0.0 7.4 7 0 0 7 7 7 3 PPR repeat Ribosomal_S18 PF01084.15 EGD95282.1 - 7.3e-15 54.5 0.1 1.2e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Cro PF09048.5 EGD95282.1 - 0.027 14.0 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Cro WD40 PF00400.27 EGD95283.1 - 3.7e-51 169.2 26.2 1.3e-08 34.3 0.3 11.3 11 0 0 11 11 11 9 WD domain, G-beta repeat PD40 PF07676.7 EGD95283.1 - 0.021 14.5 0.2 44 3.8 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Peptidase_M36 PF02128.10 EGD95287.1 - 8.5e-158 525.1 5.7 1.1e-157 524.7 4.0 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGD95287.1 - 3.3e-13 48.8 2.2 6.4e-13 47.9 1.5 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EGD95287.1 - 0.0031 17.2 0.1 0.0094 15.7 0.0 1.8 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain MFS_1 PF07690.11 EGD95289.1 - 1.7e-26 92.7 39.0 1.7e-26 92.7 27.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3328 PF11807.3 EGD95290.1 - 9.3e-31 107.2 0.1 1.2e-30 106.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3357 PF11837.3 EGD95290.1 - 0.0082 15.9 0.0 0.083 12.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3357) DIM PF08194.7 EGD95291.1 - 0.021 14.7 1.0 0.032 14.1 0.7 1.3 1 0 0 1 1 1 0 DIM protein MarB PF13999.1 EGD95291.1 - 0.074 12.6 0.4 4.5 6.9 0.1 2.1 1 1 1 2 2 2 0 MarB protein DUF3328 PF11807.3 EGD95292.1 - 2.7e-27 95.8 0.0 3.2e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EGD95293.1 - 1.6e-42 145.6 2.1 1.9e-42 145.3 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3785 PF12653.2 EGD95293.1 - 0.062 13.1 0.3 0.1 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) Methyltransf_2 PF00891.13 EGD95294.1 - 3e-28 98.6 0.1 8.5e-28 97.1 0.1 1.7 1 1 0 1 1 1 1 O-methyltransferase DUF3744 PF12558.3 EGD95296.1 - 0.54 10.7 6.3 1.1 9.8 0.8 2.7 2 1 0 2 2 2 0 ATP-binding cassette cobalt transporter Carb_anhydrase PF00194.16 EGD95297.1 - 1.4e-23 83.2 0.0 2.6e-23 82.3 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Alk_phosphatase PF00245.15 EGD95299.1 - 1.5e-107 359.9 0.0 1.8e-107 359.6 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EGD95299.1 - 4.3e-07 29.5 0.0 2.2e-05 23.9 0.0 2.6 3 0 0 3 3 3 1 Metalloenzyme superfamily FUSC_2 PF13515.1 EGD95300.1 - 4e-29 101.1 10.9 4e-29 101.1 7.6 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 EGD95300.1 - 3.8e-09 35.5 11.3 1.4e-08 33.6 5.6 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein family ALMT PF11744.3 EGD95300.1 - 2.2e-05 23.3 22.5 0.0015 17.2 6.6 3.5 3 2 0 3 3 3 2 Aluminium activated malate transporter DUF2421 PF10334.4 EGD95300.1 - 0.00065 19.3 1.1 0.00088 18.9 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) SAGA-Tad1 PF12767.2 EGD95301.1 - 1.9e-60 204.6 0.0 2.7e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PRP1_N PF06424.7 EGD95302.1 - 8.4e-54 181.4 5.9 2.3e-53 180.0 4.1 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EGD95302.1 - 4.7e-28 95.1 26.4 0.018 15.6 0.2 14.3 6 4 10 16 16 15 10 Tetratricopeptide repeat TPR_19 PF14559.1 EGD95302.1 - 1e-27 96.2 6.6 1.7e-05 25.0 0.0 9.6 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 EGD95302.1 - 3.8e-18 65.6 15.8 0.023 15.3 0.1 8.8 8 1 2 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 EGD95302.1 - 1.7e-13 49.9 7.6 0.0011 18.5 0.0 7.9 6 2 3 9 9 9 2 TPR repeat TPR_2 PF07719.12 EGD95302.1 - 4.2e-10 38.7 10.0 0.23 11.4 0.0 8.9 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGD95302.1 - 4.1e-06 26.5 1.1 13 6.3 0.0 7.7 9 0 0 9 9 8 0 Tetratricopeptide repeat NARP1 PF12569.3 EGD95302.1 - 1.2e-05 24.3 7.6 0.024 13.4 0.0 5.4 3 1 2 6 6 6 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.1 EGD95302.1 - 1.4e-05 24.5 0.1 0.35 10.7 0.1 6.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGD95302.1 - 0.00013 21.3 0.8 0.75 9.5 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGD95302.1 - 0.0022 17.9 5.4 6 6.8 0.0 5.7 6 1 0 6 6 6 1 Tetratricopeptide repeat FAT PF02259.18 EGD95302.1 - 0.0034 16.4 10.4 0.48 9.3 0.6 3.5 1 1 2 3 3 3 2 FAT domain TPR_7 PF13176.1 EGD95302.1 - 0.027 14.2 3.1 14 5.7 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RrnaAD PF00398.15 EGD95303.1 - 3.1e-59 200.1 0.0 4.5e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EGD95303.1 - 2.3e-10 40.5 0.0 4.8e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD95303.1 - 6.6e-07 29.9 0.0 1.5e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD95303.1 - 4e-05 23.0 0.0 6.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EGD95303.1 - 4.4e-05 23.8 0.0 9.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGD95303.1 - 8.5e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EGD95303.1 - 0.00021 20.8 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGD95303.1 - 0.00026 20.1 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EGD95303.1 - 0.0005 19.3 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGD95303.1 - 0.00053 19.7 0.0 0.00095 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD95303.1 - 0.00095 19.6 0.0 0.0068 16.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EGD95303.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 EGD95303.1 - 0.019 14.1 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EGD95303.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EGD95303.1 - 0.032 13.3 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.7 EGD95303.1 - 0.043 12.6 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_25 PF13649.1 EGD95303.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RabGAP-TBC PF00566.13 EGD95304.1 - 7.1e-49 166.1 0.0 2.5e-48 164.3 0.0 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain AKAP2_C PF15304.1 EGD95305.1 - 0.29 10.7 9.2 0.33 10.5 6.4 1.0 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Herpes_TAF50 PF03326.8 EGD95305.1 - 1.2 8.0 12.3 1.3 7.9 8.5 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) PRCC PF10253.4 EGD95305.1 - 1.5 9.5 11.7 1.8 9.2 8.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Nucleo_P87 PF07267.6 EGD95305.1 - 1.5 7.3 5.0 1.6 7.3 3.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PAT1 PF09770.4 EGD95305.1 - 3.3 5.8 12.1 3.6 5.7 8.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2413 PF10310.4 EGD95305.1 - 4 6.1 7.3 4.4 6.0 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RRM_1 PF00076.17 EGD95306.1 - 5.4e-35 118.8 0.5 2.6e-16 58.9 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD95306.1 - 5.9e-26 90.2 0.1 2.3e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD95306.1 - 4.6e-10 39.1 0.1 0.0011 18.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGD95306.1 - 0.0029 17.4 1.0 3.3 7.6 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif Med15 PF09606.5 EGD95306.1 - 0.068 11.3 73.7 0.098 10.8 51.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MCRS_N PF13325.1 EGD95306.1 - 0.092 12.2 1.1 0.2 11.1 0.7 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Cupin_8 PF13621.1 EGD95308.1 - 4.2e-09 36.2 0.1 9.3e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EGD95308.1 - 4.9e-09 36.4 0.0 5.1e-08 33.1 0.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EGD95308.1 - 1.1e-08 34.6 7.9 1.1e-08 34.6 5.5 2.5 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.1 EGD95308.1 - 3.5 7.0 9.8 4 6.8 5.3 2.4 2 0 0 2 2 2 0 PHD-finger COG4 PF08318.7 EGD95309.1 - 7.3e-101 337.2 0.0 9.6e-101 336.8 0.0 1.1 1 0 0 1 1 1 1 COG4 transport protein FtsL PF04999.8 EGD95309.1 - 0.28 10.9 1.7 39 4.0 0.3 3.1 2 1 1 3 3 3 0 Cell division protein FtsL SIR2 PF02146.12 EGD95310.1 - 1.2e-56 191.2 0.0 1.8e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EGD95310.1 - 0.1 12.3 0.0 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Hexokinase_2 PF03727.11 EGD95311.1 - 8.1e-86 287.1 0.0 1.1e-85 286.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EGD95311.1 - 4.7e-75 251.4 0.0 6.3e-75 251.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Reprolysin_4 PF13583.1 EGD95311.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like WD40 PF00400.27 EGD95312.1 - 3.1e-06 26.8 1.6 1.3 9.0 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGD95312.1 - 0.19 10.4 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like DUF3661 PF12400.3 EGD95313.1 - 6.2e-39 133.0 6.5 9.1e-39 132.4 4.5 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein FixQ PF05545.6 EGD95313.1 - 1.8 8.2 4.5 5.9 6.6 3.1 1.9 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Mucin PF01456.12 EGD95313.1 - 2.9 7.6 19.8 5.2 6.8 13.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RRM_1 PF00076.17 EGD95314.1 - 7.2e-19 67.1 0.3 1.1e-18 66.5 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD95314.1 - 1.8e-13 50.2 0.0 2.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD95314.1 - 8.9e-10 38.2 0.1 1.4e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ammonium_transp PF00909.16 EGD95315.1 - 2.7e-115 385.0 28.8 3.1e-115 384.8 19.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family E1-E2_ATPase PF00122.15 EGD95316.1 - 7.1e-79 264.0 0.2 1.3e-78 263.1 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD95316.1 - 3.7e-45 153.7 0.2 3.7e-45 153.7 0.2 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD95316.1 - 3.4e-31 109.3 0.0 3.4e-30 106.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD95316.1 - 2.9e-22 77.8 0.0 7e-22 76.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGD95316.1 - 3.7e-16 59.8 0.0 9.4e-16 58.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD95316.1 - 1.2e-13 50.7 0.0 2.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGD95316.1 - 8.1e-06 25.5 1.4 0.00018 21.2 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 EGD95317.1 - 3.3e-39 133.2 0.0 5.3e-39 132.6 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EGD95317.1 - 8.8e-07 28.0 0.2 1.8e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EGD95317.1 - 0.0046 16.5 0.0 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 ScpA/B protein Zn_clus PF00172.13 EGD95321.1 - 0.0029 17.4 9.0 0.0029 17.4 6.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EGD95321.1 - 0.033 13.9 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 PAS fold Flavokinase PF01687.12 EGD95323.1 - 4.3e-33 113.8 0.0 6.9e-33 113.1 0.0 1.3 1 1 0 1 1 1 1 Riboflavin kinase DUF221 PF02714.10 EGD95324.1 - 2.3e-108 361.8 27.6 2.3e-108 361.8 19.1 2.0 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGD95324.1 - 2.4e-45 153.9 1.0 2.4e-45 153.9 0.7 3.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EGD95324.1 - 2e-14 53.2 0.8 5.8e-14 51.7 0.0 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EGD95324.1 - 8.8e-06 26.1 10.9 0.0014 19.0 0.9 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) AAA_13 PF13166.1 EGD95324.1 - 0.031 12.7 0.2 0.031 12.7 0.1 1.6 2 0 0 2 2 2 0 AAA domain SnoaL_2 PF12680.2 EGD95326.1 - 5.3e-06 26.7 0.0 9.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EGD95326.1 - 0.00015 21.3 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.13 EGD95326.1 - 0.055 12.7 0.0 0.87 8.8 0.0 2.4 2 1 1 3 3 3 0 Dienelactone hydrolase family Indigoidine_A PF04227.7 EGD95327.1 - 4.3e-118 393.8 0.9 6e-118 393.3 0.6 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EGD95327.1 - 8.7e-11 41.4 0.0 3.5e-05 23.0 0.0 3.2 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.9 EGD95328.1 - 4e-139 463.8 0.1 4.6e-139 463.6 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Ribosomal_L23eN PF03939.8 EGD95328.1 - 0.1 12.6 0.2 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain VTC PF09359.5 EGD95329.1 - 3.6e-101 337.9 0.4 5.2e-101 337.3 0.2 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EGD95329.1 - 4.7e-29 102.0 2.4 1.4e-15 57.8 0.3 3.1 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 EGD95329.1 - 1.9e-09 37.5 5.2 2.1e-09 37.4 2.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MCM PF00493.18 EGD95330.1 - 6.2e-140 465.6 0.0 8.2e-140 465.2 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGD95330.1 - 1.4e-25 90.0 0.0 6.4e-25 87.9 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGD95330.1 - 6.7e-06 25.4 0.0 0.00026 20.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGD95330.1 - 1.9e-05 24.4 0.1 0.00012 21.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGD95330.1 - 0.0037 16.8 0.0 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 EGD95330.1 - 0.1 11.2 5.0 0.038 12.6 0.3 2.1 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 EGD95331.1 - 4.4e-08 33.3 0.1 0.0093 16.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD95331.1 - 0.033 14.6 0.0 7.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) HeLo PF14479.1 EGD95332.1 - 9.3e-10 38.6 0.1 2.1e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation Band_7 PF01145.20 EGD95333.1 - 3e-24 85.9 3.3 4.3e-24 85.3 2.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.14 EGD95333.1 - 0.13 11.5 2.8 0.18 11.0 1.9 1.3 1 1 0 1 1 1 0 MraW methylase family CSTF2_hinge PF14327.1 EGD95334.1 - 5.7e-30 103.2 2.5 5.7e-30 103.2 1.8 2.2 2 1 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EGD95334.1 - 1.3e-19 69.6 0.0 2.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EGD95334.1 - 2.1e-17 62.1 7.2 2.1e-17 62.1 5.0 2.2 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_6 PF14259.1 EGD95334.1 - 3.6e-16 58.8 0.0 6.4e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD95334.1 - 2.7e-07 30.3 0.0 4.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 EGD95334.1 - 0.022 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 SWI-SNF_Ssr4 PF08549.5 EGD95334.1 - 0.069 11.4 11.1 0.11 10.8 7.7 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SNF2_N PF00176.18 EGD95335.1 - 2.6e-24 85.5 0.1 1.4e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 EGD95335.1 - 5.9e-19 68.3 0.0 1.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.26 EGD95335.1 - 0.00053 19.7 0.0 0.0041 16.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EGD95335.1 - 3.4 7.7 21.7 1.4 9.0 7.0 3.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD95335.1 - 7.7 6.3 28.5 0.34 10.6 8.2 2.8 2 0 0 2 2 2 0 zinc-RING finger domain 2Fe-2S_thioredx PF01257.14 EGD95336.1 - 3e-59 198.7 0.1 3.7e-59 198.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF4139 PF13598.1 EGD95337.1 - 2.2e-40 138.9 13.8 4.5e-19 68.9 0.0 4.2 3 1 1 4 4 4 3 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EGD95337.1 - 4.7e-09 36.6 0.0 4.7e-09 36.6 0.0 3.4 3 1 1 4 4 4 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.1 EGD95337.1 - 0.1 12.8 9.3 0.21 11.8 6.4 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region NOA36 PF06524.7 EGD95337.1 - 0.32 10.2 3.5 0.77 8.9 2.4 1.6 1 0 0 1 1 1 0 NOA36 protein V_ATPase_I PF01496.14 EGD95337.1 - 0.5 8.1 6.0 0.74 7.6 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YhzD PF14120.1 EGD95337.1 - 0.95 9.4 6.3 2.4 8.1 4.4 1.6 1 0 0 1 1 1 0 YhzD-like protein Sua5_yciO_yrdC PF01300.13 EGD95338.1 - 2.6e-54 183.1 0.0 4.5e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EGD95338.1 - 5e-26 91.2 0.0 9.5e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding FbpA PF05833.6 EGD95339.1 - 1e-34 119.8 10.6 2.1e-34 118.8 7.3 1.5 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 EGD95339.1 - 1.2e-33 115.1 0.0 5.2e-33 113.0 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 EGD95339.1 - 4.1e-16 58.6 0.0 1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) LRR19-TM PF15176.1 EGD95339.1 - 6.2 6.5 6.2 24 4.6 4.3 2.0 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Clat_adaptor_s PF01217.15 EGD95340.1 - 4.9e-14 52.2 0.0 1.1e-12 47.8 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain GrpE PF01025.14 EGD95341.1 - 0.91 9.0 4.5 0.35 10.3 1.0 1.8 2 0 0 2 2 2 0 GrpE TPR_MLP1_2 PF07926.7 EGD95342.1 - 0.00034 20.3 17.3 0.00034 20.3 12.0 3.0 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF948 PF06103.6 EGD95342.1 - 0.0037 17.1 1.6 0.0078 16.0 1.1 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DUF1515 PF07439.6 EGD95342.1 - 0.11 12.3 10.5 0.029 14.1 2.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Bacillus_HBL PF05791.6 EGD95342.1 - 0.66 9.3 8.1 0.29 10.4 2.8 2.2 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Laminin_II PF06009.7 EGD95342.1 - 1.6 8.4 10.9 5 6.8 7.6 1.8 1 0 0 1 1 1 0 Laminin Domain II ERM PF00769.14 EGD95342.1 - 2.4 7.6 32.3 0.55 9.7 1.1 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 EGD95342.1 - 3 5.5 7.9 5.4 4.7 5.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 EGD95342.1 - 4.1 7.3 11.5 13 5.7 1.1 4.0 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF3573 PF12097.3 EGD95342.1 - 5.2 5.5 5.0 2.4 6.6 1.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Phage_GP20 PF06810.6 EGD95342.1 - 5.4 6.4 26.9 0.038 13.4 9.6 3.4 3 1 0 3 3 3 0 Phage minor structural protein GP20 HAUS6_N PF14661.1 EGD95342.1 - 7.9 5.7 15.9 30 3.8 10.7 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Pyridoxal_deC PF00282.14 EGD95343.1 - 7.6e-18 64.1 0.0 1.1e-09 37.2 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Ribosomal_L16 PF00252.13 EGD95344.1 - 1.1e-30 106.0 0.1 1.6e-30 105.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e UBN2_2 PF14227.1 EGD95346.1 - 0.031 13.8 0.0 0.092 12.3 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type FAD_binding_2 PF00890.19 EGD95347.1 - 2.5e-84 283.5 0.2 3.4e-84 283.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGD95347.1 - 7.6e-12 44.7 2.1 8.4e-11 41.3 1.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGD95347.1 - 6.6e-11 41.9 3.0 4.1e-09 36.0 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGD95347.1 - 4.6e-08 32.5 0.2 0.0017 17.4 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EGD95347.1 - 5.2e-07 29.7 0.2 6e-06 26.2 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD95347.1 - 6.5e-07 29.2 0.9 1.8e-06 27.8 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGD95347.1 - 8.6e-06 24.4 2.0 1.5e-05 23.7 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EGD95347.1 - 5.3e-05 22.4 1.5 7.3e-05 21.9 0.3 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EGD95347.1 - 0.003 17.6 0.2 0.0083 16.1 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UPF0227 PF05728.7 EGD95347.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) GIDA PF01134.17 EGD95347.1 - 0.13 11.1 0.7 0.23 10.2 0.5 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AAA PF00004.24 EGD95348.1 - 1.7e-19 70.3 0.0 4.9e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGD95348.1 - 0.00023 21.2 0.0 0.00094 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGD95348.1 - 0.00024 21.9 0.5 0.0025 18.6 0.0 2.9 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 EGD95348.1 - 0.00032 20.9 0.9 0.0012 19.1 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EGD95348.1 - 0.00039 20.1 0.1 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EGD95348.1 - 0.00043 20.0 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGD95348.1 - 0.0013 18.8 0.5 0.013 15.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGD95348.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zot PF05707.7 EGD95348.1 - 0.0058 16.1 0.2 0.12 11.8 0.0 2.3 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_14 PF13173.1 EGD95348.1 - 0.0094 15.8 0.0 0.035 13.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 EGD95348.1 - 0.016 14.6 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 EGD95348.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGD95348.1 - 0.03 14.2 0.0 0.078 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGD95348.1 - 0.035 13.2 0.0 0.082 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EGD95348.1 - 0.057 13.3 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EGD95348.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain T2SE PF00437.15 EGD95348.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EGD95348.1 - 0.16 11.0 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 KaiC FA_hydroxylase PF04116.8 EGD95349.1 - 5e-17 62.3 12.5 5e-17 62.3 8.6 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HA2 PF04408.18 EGD95350.1 - 8.8e-18 64.2 1.0 1.7e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGD95350.1 - 2e-16 59.8 0.0 6e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGD95350.1 - 9.9e-13 47.7 0.0 4.6e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD95350.1 - 0.00017 21.1 0.0 0.00047 19.6 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 EGD95350.1 - 0.0024 17.3 0.0 0.0069 15.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGD95350.1 - 0.02 14.9 0.0 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGD95350.1 - 0.085 11.9 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 EGD95350.1 - 0.091 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zn_clus PF00172.13 EGD95351.1 - 3.6e-08 33.1 11.8 6.4e-08 32.3 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGD95351.1 - 0.0044 15.6 0.0 0.011 14.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.8 EGD95352.1 - 1.1e-18 67.5 2.1 2e-18 66.7 1.5 1.3 1 1 0 1 1 1 1 RTA1 like protein DUF950 PF06106.6 EGD95353.1 - 0.066 13.2 0.0 0.1 12.6 0.0 1.3 1 1 0 1 1 1 0 Staphylococcus protein of unknown function (DUF950) Phosducin PF02114.11 EGD95353.1 - 0.13 10.9 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosducin Fungal_lectin PF07938.7 EGD95354.1 - 3.5e-68 230.1 1.9 4.1e-68 229.9 1.3 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin TauD PF02668.11 EGD95355.1 - 3.7e-24 85.7 0.0 4.8e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TSSC4 PF15264.1 EGD95355.1 - 0.16 12.4 0.1 0.25 11.7 0.1 1.3 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 GAGA PF09237.6 EGD95356.1 - 0.086 12.4 0.1 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 GAGA factor FinO_N PF12602.3 EGD95356.1 - 0.088 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Fertility inhibition protein N terminal Complex1_LYR PF05347.10 EGD95357.1 - 1.7e-08 34.1 0.1 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGD95357.1 - 2.1e-06 27.8 0.0 3.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EGD95357.1 - 4.5e-05 23.8 0.0 5.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_26 PF13659.1 EGD95358.1 - 1.6e-16 60.3 0.0 2.4e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD95358.1 - 0.0067 15.8 1.8 0.94 8.8 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.1 EGD95358.1 - 0.018 14.6 0.0 0.044 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGD95358.1 - 0.044 14.2 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.17 EGD95359.1 - 9.8e-16 57.0 0.0 1.3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGD95359.1 - 0.00014 21.6 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Gar1 PF04410.9 EGD95359.1 - 0.082 12.3 0.1 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region API5 PF05918.6 EGD95359.1 - 0.34 9.3 15.0 0.43 9.0 10.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2763 PF10961.3 EGD95359.1 - 4.3 7.8 9.7 7.3 7.0 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) F-box-like PF12937.2 EGD95360.1 - 1.7e-05 24.4 0.9 4.8e-05 22.9 0.1 2.2 1 1 1 2 2 2 1 F-box-like F-box PF00646.28 EGD95360.1 - 0.003 17.1 0.1 0.0093 15.5 0.1 1.9 1 0 0 1 1 1 1 F-box domain zf-C2H2 PF00096.21 EGD95362.1 - 6.7e-05 23.0 4.6 0.076 13.3 0.4 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD95362.1 - 0.00011 22.2 3.4 0.056 13.8 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGD95362.1 - 0.047 13.9 0.1 0.23 11.8 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double domain EBV-NA3 PF05009.7 EGD95365.1 - 0.17 11.0 3.7 0.19 10.9 2.5 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF4407 PF14362.1 EGD95365.1 - 0.95 8.3 14.5 1.2 8.0 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NARP1 PF12569.3 EGD95365.1 - 1.5 7.4 19.7 0.87 8.2 12.6 1.3 1 1 0 1 1 1 0 NMDA receptor-regulated protein 1 FLO_LFY PF01698.11 EGD95365.1 - 2.9 6.6 11.5 3.2 6.5 8.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein U79_P34 PF03064.11 EGD95365.1 - 4.4 6.7 14.6 6.4 6.2 10.1 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC27 PF09507.5 EGD95365.1 - 4.9 6.2 23.3 5.3 6.1 16.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Adeno_terminal PF02459.10 EGD95365.1 - 4.9 5.1 7.3 5.2 5.1 5.1 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Zip PF02535.17 EGD95365.1 - 5.5 5.9 6.4 6.3 5.7 4.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GTP_EFTU PF00009.22 EGD95366.1 - 5.5e-10 38.9 0.0 1.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EGD95366.1 - 0.0078 16.5 0.0 0.025 14.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EGD95366.1 - 0.015 14.8 0.3 0.037 13.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGD95366.1 - 0.021 14.7 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EGD95366.1 - 0.037 13.4 0.1 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EGD95366.1 - 0.038 13.9 0.2 0.094 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EGD95366.1 - 0.049 13.9 0.1 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGD95366.1 - 0.055 12.6 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EGD95366.1 - 0.084 12.3 0.1 4.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 EGD95366.1 - 0.21 12.0 0.2 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein Pkr1 PF08636.5 EGD95367.1 - 5.4e-32 109.6 4.4 7.7e-32 109.1 3.1 1.2 1 0 0 1 1 1 1 ER protein Pkr1 Phage_Gp23 PF10669.4 EGD95367.1 - 0.18 11.9 0.6 0.52 10.4 0.4 1.7 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Cullin PF00888.17 EGD95368.1 - 6.8e-46 156.9 0.0 1.2e-45 156.1 0.0 1.3 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EGD95368.1 - 9.2e-22 77.0 0.1 2.3e-21 75.7 0.1 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 SNF2_N PF00176.18 EGD95369.1 - 3.8e-28 98.1 0.0 1.9e-27 95.8 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGD95369.1 - 7.6e-07 29.1 0.0 1.8e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGD95369.1 - 0.087 12.3 0.0 0.44 10.0 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF4139 PF13598.1 EGD95370.1 - 0.056 12.7 3.1 0.064 12.5 2.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) DUF390 PF04094.9 EGD95370.1 - 0.083 10.9 9.2 0.1 10.6 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Ribosomal_60s PF00428.14 EGD95370.1 - 0.18 12.2 10.9 0.23 11.9 7.6 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Endonuc_Holl PF10107.4 EGD95370.1 - 0.29 10.8 1.2 0.35 10.5 0.9 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF4230 PF14014.1 EGD95370.1 - 2.6 7.9 5.8 3.6 7.4 4.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4230) APH PF01636.18 EGD95371.1 - 0.0003 20.5 0.1 0.00057 19.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family F-box-like PF12937.2 EGD95372.1 - 1.1e-09 37.8 0.8 3.1e-09 36.4 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD95372.1 - 7.8e-07 28.5 0.5 2e-06 27.2 0.4 1.7 1 0 0 1 1 1 1 F-box domain Apc3 PF12895.2 EGD95372.1 - 0.091 12.9 0.1 0.25 11.4 0.2 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EGD95372.1 - 0.098 12.6 0.6 3 7.9 0.4 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGD95372.1 - 0.1 12.2 0.6 0.41 10.3 0.2 2.0 1 1 1 2 2 2 0 TPR repeat Gemini_AL2 PF01440.11 EGD95372.1 - 3.8 7.6 6.0 0.38 10.8 0.7 2.0 2 0 0 2 2 2 0 Geminivirus AL2 protein Mito_carr PF00153.22 EGD95373.1 - 3.4e-62 206.1 0.4 1.6e-21 75.8 0.2 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF4175 PF13779.1 EGD95374.1 - 0.43 8.2 30.4 0.59 7.7 21.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) eIF-3_zeta PF05091.7 EGD95374.1 - 0.97 7.9 18.2 0.016 13.8 7.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.7 EGD95374.1 - 1.3 8.8 8.6 2.6 7.8 5.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 EGD95374.1 - 1.6 8.4 18.8 0.015 15.1 5.5 2.4 2 1 0 2 2 2 0 DDHD domain Paramyxo_ncap PF00973.14 EGD95374.1 - 9.4 4.8 6.6 17 3.9 4.6 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein KAR9 PF08580.5 EGD95375.1 - 2.5e-119 399.5 0.0 2.5e-119 399.5 0.0 2.4 2 1 0 2 2 2 1 Yeast cortical protein KAR9 Tim17 PF02466.14 EGD95375.1 - 0.053 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family HALZ PF02183.13 EGD95375.1 - 1.7 8.3 3.6 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Med25_SD1 PF11235.3 EGD95376.1 - 2.2 8.5 6.4 0.41 10.9 1.3 1.9 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 DUF3449 PF11931.3 EGD95376.1 - 4.6 6.7 7.5 8 5.9 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) CRAL_TRIO PF00650.15 EGD95377.1 - 2.5e-28 98.5 0.0 3.7e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGD95377.1 - 1.1e-09 38.2 0.2 4e-09 36.4 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGD95377.1 - 0.0043 16.9 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Acylphosphatase PF00708.13 EGD95379.1 - 2.3e-19 69.3 0.1 2.5e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase AOX PF01786.12 EGD95380.1 - 1.4e-91 305.4 0.0 1.7e-91 305.2 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase adh_short PF00106.20 EGD95381.1 - 1.2e-25 90.3 0.0 1.6e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD95381.1 - 3.6e-25 89.1 0.0 4.5e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD95381.1 - 1.6e-07 31.1 0.0 2.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD95381.1 - 0.0068 15.8 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EGD95381.1 - 0.0097 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 EGD95381.1 - 0.035 13.2 0.1 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TMEMspv1-c74-12 PF11044.3 EGD95382.1 - 0.038 13.5 4.4 0.067 12.7 3.1 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein MBOAT PF03062.14 EGD95384.1 - 2.3e-47 161.7 11.7 4.4e-47 160.7 8.1 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family FA_desaturase PF00487.19 EGD95385.1 - 1.3e-33 116.4 22.5 2.3e-33 115.7 15.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGD95385.1 - 3.6e-09 36.2 0.0 7.8e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-HIT PF04438.11 EGD95388.1 - 2.7e-10 39.7 7.0 4e-10 39.1 4.9 1.3 1 0 0 1 1 1 1 HIT zinc finger Dopey_N PF04118.9 EGD95389.1 - 1.2e-122 408.5 0.0 2e-121 404.5 0.0 2.6 3 0 0 3 3 3 1 Dopey, N-terminal Mon1 PF03164.9 EGD95390.1 - 1.3e-116 389.6 0.0 1.7e-116 389.2 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 DEAD PF00270.24 EGD95391.1 - 9e-22 77.3 0.0 1.9e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD95391.1 - 1.9e-21 75.6 0.1 5.3e-18 64.6 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 EGD95391.1 - 2.2e-14 53.0 0.0 5e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EGD95391.1 - 4.9e-08 32.5 0.0 1.2e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 HRDC domain RHS_repeat PF05593.9 EGD95392.1 - 1.2 9.3 4.7 0.65 10.2 0.5 2.4 2 0 0 2 2 2 0 RHS Repeat MutS_V PF00488.16 EGD95393.1 - 1.3e-88 296.4 0.0 2.1e-88 295.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGD95393.1 - 2.9e-37 128.4 0.4 6.3e-37 127.3 0.3 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGD95393.1 - 6.3e-28 97.0 0.0 1.3e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EGD95393.1 - 4.3e-10 39.7 0.0 2.2e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EGD95393.1 - 4.7e-08 33.1 0.3 1.3e-07 31.7 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV LpxB PF02684.10 EGD95393.1 - 0.036 12.6 0.0 0.067 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Ribosomal_S28e PF01200.13 EGD95394.1 - 2.5e-33 113.6 0.7 2.6e-33 113.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.13 EGD95395.1 - 6.3e-51 172.1 0.0 9.3e-51 171.6 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EGD95395.1 - 2.2e-27 94.7 0.2 4.6e-27 93.7 0.2 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EGD95395.1 - 0.0072 15.9 0.0 0.024 14.2 0.0 1.8 1 1 0 1 1 1 1 NMT1/THI5 like AAA PF00004.24 EGD95396.1 - 9.1e-55 184.4 0.0 2e-43 147.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EGD95396.1 - 2.5e-29 101.1 0.3 5e-29 100.1 0.2 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EGD95396.1 - 3.4e-10 40.2 1.9 2.6e-05 24.3 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain NACHT PF05729.7 EGD95396.1 - 5.9e-07 29.3 0.3 0.00068 19.3 0.0 3.6 3 0 0 3 3 3 1 NACHT domain AAA_2 PF07724.9 EGD95396.1 - 7.9e-07 29.1 0.0 0.042 13.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EGD95396.1 - 6.6e-06 25.6 0.1 0.011 15.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EGD95396.1 - 2.2e-05 24.3 0.0 0.24 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGD95396.1 - 2.4e-05 24.5 0.7 0.74 9.9 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGD95396.1 - 3.1e-05 23.6 0.0 0.075 12.7 0.0 3.1 3 0 0 3 3 2 1 Part of AAA domain AAA_17 PF13207.1 EGD95396.1 - 3.1e-05 24.7 0.0 0.21 12.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EGD95396.1 - 3.7e-05 22.8 0.0 0.017 14.1 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EGD95396.1 - 0.00014 22.1 0.0 0.07 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGD95396.1 - 0.0003 19.9 0.0 0.71 8.9 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.9 EGD95396.1 - 0.00052 19.7 0.1 1.6 8.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EGD95396.1 - 0.00055 19.3 2.2 3.1 7.1 0.0 4.0 2 2 2 4 4 4 1 AAA domain UPF0079 PF02367.12 EGD95396.1 - 0.0027 17.3 0.2 0.13 11.9 0.0 3.0 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 EGD95396.1 - 0.0035 16.1 0.0 1.7 7.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 EGD95396.1 - 0.0043 16.9 0.0 0.4 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGD95396.1 - 0.0045 16.9 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EGD95396.1 - 0.0067 15.4 0.2 0.18 10.7 0.0 2.5 2 1 1 3 3 2 1 KAP family P-loop domain RNA_helicase PF00910.17 EGD95396.1 - 0.008 16.3 0.0 6.1 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Sigma54_activ_2 PF14532.1 EGD95396.1 - 0.015 15.3 0.0 3.1 7.8 0.0 3.1 3 0 0 3 3 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGD95396.1 - 0.016 14.3 0.4 0.86 8.7 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EGD95396.1 - 0.025 14.8 0.0 4.7 7.5 0.0 2.7 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 EGD95396.1 - 0.03 13.2 0.1 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EGD95396.1 - 0.057 12.9 0.2 0.28 10.6 0.0 2.3 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 EGD95396.1 - 0.074 12.1 0.1 12 4.9 0.0 2.5 2 0 0 2 2 2 0 KaiC SKI PF01202.17 EGD95396.1 - 0.086 12.7 0.0 4.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.11 EGD95396.1 - 0.12 11.6 0.1 13 4.9 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein APS_kinase PF01583.15 EGD95396.1 - 0.13 11.8 0.1 0.51 9.9 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF2075 PF09848.4 EGD95396.1 - 0.15 10.9 0.0 11 4.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EGD95396.1 - 0.16 11.3 0.5 6 6.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.21 EGD95396.1 - 0.19 11.1 0.0 8 5.9 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 EGD95396.1 - 0.22 11.3 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family Arch_ATPase PF01637.13 EGD95396.1 - 0.32 10.6 0.0 33 4.0 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase MCM PF00493.18 EGD95397.1 - 1.1e-135 451.7 0.0 2.1e-135 450.7 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGD95397.1 - 6.4e-27 94.4 0.0 2.4e-26 92.6 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGD95397.1 - 3.3e-07 29.6 0.0 4.8e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGD95397.1 - 2.6e-05 23.9 0.0 6.4e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGD95397.1 - 0.018 15.0 1.3 6.8 6.6 0.1 3.4 2 1 0 3 3 3 0 AAA ATPase domain Mg_chelatase_2 PF13335.1 EGD95397.1 - 0.022 15.1 0.1 0.1 13.0 0.0 2.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGD95397.1 - 0.074 12.6 0.0 0.22 11.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Nucleos_tra2_C PF07662.8 EGD95398.1 - 0.12 11.8 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus EGF_CA PF07645.10 EGD95399.1 - 5.5e-06 26.2 5.1 5.5e-06 26.2 3.6 1.7 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.2 EGD95399.1 - 0.0023 17.8 4.9 0.0023 17.8 3.4 2.1 2 1 0 2 2 2 1 EGF domain cEGF PF12662.2 EGD95399.1 - 0.0048 16.4 0.1 0.0048 16.4 0.1 2.2 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.22 EGD95399.1 - 0.0052 16.7 5.4 0.023 14.6 3.6 2.2 1 1 0 1 1 1 1 EGF-like domain FXa_inhibition PF14670.1 EGD95399.1 - 0.0067 16.5 4.8 0.0067 16.5 3.3 2.5 2 1 0 2 2 2 1 Coagulation Factor Xa inhibitory site MFS_1 PF07690.11 EGD95401.1 - 1.1e-39 136.1 30.7 2.1e-33 115.5 17.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGD95401.1 - 0.0066 14.5 6.6 0.13 10.2 2.9 2.7 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Paired_CXXCH_1 PF09699.5 EGD95403.1 - 0.017 14.5 0.4 0.031 13.7 0.3 1.4 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) SNF2_N PF00176.18 EGD95404.1 - 0.0009 18.1 0.0 0.0011 17.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain IBN_N PF03810.14 EGD95405.1 - 0.19 11.6 0.6 3.8 7.4 0.0 2.8 3 0 0 3 3 3 0 Importin-beta N-terminal domain AMP-binding PF00501.23 EGD95406.1 - 6.9e-90 301.4 0.0 8.5e-90 301.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD95406.1 - 4.3e-13 50.0 0.1 2.1e-12 47.8 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain LRR19-TM PF15176.1 EGD95407.1 - 0.058 13.0 0.0 0.071 12.7 0.0 1.3 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain CMAS PF02353.15 EGD95408.1 - 2.4e-56 190.8 0.0 3.2e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGD95408.1 - 1.7e-11 44.0 0.0 5.3e-11 42.4 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD95408.1 - 3.2e-07 30.7 0.0 6.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD95408.1 - 0.0015 18.9 0.0 0.0037 17.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD95408.1 - 0.0022 18.5 0.0 0.0055 17.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD95408.1 - 0.0046 16.9 0.0 0.018 15.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EGD95408.1 - 0.0096 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 EGD95408.1 - 0.017 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 EGD95408.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGD95408.1 - 0.073 13.4 0.0 0.18 12.2 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain PCMT PF01135.14 EGD95408.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Dicty_REP PF05086.7 EGD95409.1 - 0.35 8.5 6.1 0.47 8.1 4.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tropomyosin_1 PF12718.2 EGD95410.1 - 3.1e-46 156.7 35.8 4e-46 156.4 24.8 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EGD95410.1 - 1.5e-10 40.5 36.3 1.9e-06 27.1 10.9 2.1 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.1 EGD95410.1 - 0.00014 21.1 32.2 0.00072 18.8 15.7 2.1 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding KLRAQ PF10205.4 EGD95410.1 - 0.0005 20.0 10.7 0.0005 20.0 7.4 3.1 1 1 1 3 3 3 1 Predicted coiled-coil domain-containing protein AAA_13 PF13166.1 EGD95410.1 - 0.0016 17.0 22.2 0.0021 16.6 15.4 1.1 1 0 0 1 1 1 1 AAA domain CENP-F_leu_zip PF10473.4 EGD95410.1 - 0.0017 18.2 6.1 0.0017 18.2 4.2 3.3 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 EGD95410.1 - 0.0048 16.6 20.5 0.0052 16.5 5.6 2.1 1 1 1 2 2 2 1 Laminin Domain II Spc7 PF08317.6 EGD95410.1 - 0.0064 15.1 29.4 0.44 9.1 9.1 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein Med9 PF07544.8 EGD95410.1 - 0.011 15.4 6.9 0.011 15.4 4.8 3.5 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ADIP PF11559.3 EGD95410.1 - 0.011 15.5 33.5 0.16 11.8 7.5 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Meckelin PF09773.4 EGD95410.1 - 0.012 13.4 1.0 0.012 13.3 0.7 1.2 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) TMP_2 PF06791.8 EGD95410.1 - 0.015 14.9 4.0 0.012 15.2 2.0 1.5 1 1 1 2 2 2 0 Prophage tail length tape measure protein Sugarporin_N PF11471.3 EGD95410.1 - 0.017 14.7 2.6 0.017 14.7 1.8 3.6 3 2 1 4 4 2 0 Maltoporin periplasmic N-terminal extension TPR_MLP1_2 PF07926.7 EGD95410.1 - 0.028 14.1 34.7 0.2 11.4 5.3 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EGD95410.1 - 0.041 12.8 31.3 0.09 11.7 15.0 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 HATPase_c_2 PF13581.1 EGD95410.1 - 0.042 13.6 1.0 0.055 13.2 0.7 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain IncA PF04156.9 EGD95410.1 - 0.049 13.2 33.9 67 2.9 23.5 2.2 1 1 0 1 1 1 0 IncA protein Mod_r PF07200.8 EGD95410.1 - 0.08 12.8 28.1 0.37 10.6 13.7 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ATG16 PF08614.6 EGD95410.1 - 0.12 12.2 31.1 2.1 8.1 9.9 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EGD95410.1 - 0.14 11.3 4.5 1.5 7.9 0.3 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ERM PF00769.14 EGD95410.1 - 0.14 11.6 37.4 0.087 12.3 12.4 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3584 PF12128.3 EGD95410.1 - 0.15 9.3 29.7 0.18 9.0 20.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.4 EGD95410.1 - 0.17 12.0 23.0 0.56 10.3 0.6 3.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 EGD95410.1 - 0.29 11.5 27.4 0.18 12.1 7.8 2.9 1 1 1 2 2 1 0 Protein of unknown function (DUF972) Laminin_I PF06008.9 EGD95410.1 - 0.3 10.3 28.1 2.9 7.1 6.7 2.7 1 1 2 3 3 3 0 Laminin Domain I TMF_DNA_bd PF12329.3 EGD95410.1 - 0.33 10.8 37.1 0.18 11.6 10.3 3.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PilJ PF13675.1 EGD95410.1 - 0.35 11.1 14.6 1.6 9.0 4.9 2.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.7 EGD95410.1 - 0.35 10.6 17.0 0.27 11.0 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MCPsignal PF00015.16 EGD95410.1 - 0.61 9.5 14.6 2.7 7.4 7.3 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain bZIP_1 PF00170.16 EGD95410.1 - 0.62 10.0 26.8 0.81 9.6 0.6 4.3 1 1 3 4 4 4 0 bZIP transcription factor EzrA PF06160.7 EGD95410.1 - 0.63 8.1 25.1 0.27 9.3 4.8 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Filament PF00038.16 EGD95410.1 - 0.8 9.1 30.1 3.1 7.1 10.4 2.0 1 1 1 2 2 2 0 Intermediate filament protein APG6 PF04111.7 EGD95410.1 - 1.1 8.1 35.0 1.7 7.5 14.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF812 PF05667.6 EGD95410.1 - 1.4 7.3 30.6 0.74 8.2 4.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF4200 PF13863.1 EGD95410.1 - 1.4 8.8 37.8 1.6 8.6 15.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) IFT46_B_C PF12317.3 EGD95410.1 - 1.7 7.9 8.9 0.5 9.7 3.7 1.7 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Orbi_VP5 PF00901.12 EGD95410.1 - 1.7 6.7 21.0 2.2 6.3 14.5 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF1465 PF07323.7 EGD95410.1 - 2 7.9 17.9 0.57 9.7 4.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Fib_alpha PF08702.5 EGD95410.1 - 2.1 8.4 21.6 2.2 8.4 7.2 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 EGD95410.1 - 2.8 7.5 32.9 12 5.5 12.0 2.2 1 1 1 2 2 2 0 Mnd1 family Syntaxin-6_N PF09177.6 EGD95410.1 - 2.8 8.4 21.6 17 5.8 6.9 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Striatin PF08232.7 EGD95410.1 - 3 8.1 29.5 2.2 8.6 13.0 2.5 1 1 0 2 2 2 0 Striatin family Cep57_MT_bd PF06657.8 EGD95410.1 - 3.1 7.8 23.2 0.11 12.3 2.8 3.8 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF3287 PF11690.3 EGD95410.1 - 3.4 7.7 12.5 66 3.6 7.8 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) FUSC PF04632.7 EGD95410.1 - 3.8 5.8 7.1 3.9 5.7 5.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family BRCA-2_OB3 PF09104.5 EGD95410.1 - 4 7.2 7.9 8.8 6.1 0.5 3.3 1 1 3 4 4 4 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 FlaC_arch PF05377.6 EGD95410.1 - 4.9 7.1 20.8 3.8 7.4 0.1 4.3 3 1 0 4 4 4 0 Flagella accessory protein C (FlaC) MS_channel PF00924.13 EGD95410.1 - 5.3 6.3 5.3 9 5.5 3.7 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel Uds1 PF15456.1 EGD95410.1 - 5.4 7.0 27.7 13 5.7 15.2 3.0 1 1 1 2 2 2 0 Up-regulated During Septation Peptidase_S64 PF08192.6 EGD95410.1 - 6.4 4.9 13.3 7.4 4.7 9.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF724 PF05266.9 EGD95410.1 - 8.5 5.9 29.0 1.2 8.7 7.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Phage_GP20 PF06810.6 EGD95410.1 - 9 5.7 28.2 12 5.3 4.9 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Nup54 PF13874.1 EGD95410.1 - 9.1 5.9 27.1 7.9 6.1 6.4 3.2 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 SlyX PF04102.7 EGD95410.1 - 9.1 6.7 26.1 4.9 7.6 1.3 3.5 1 1 3 4 4 3 0 SlyX Nop25 PF09805.4 EGD95411.1 - 1e-37 129.2 9.2 1e-37 129.2 6.4 3.1 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Nop53 PF07767.6 EGD95411.1 - 4.1 6.2 37.8 1.4 7.8 4.1 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) ATP-synt_S1 PF05827.7 EGD95412.1 - 3.2e-48 164.4 0.6 1.2e-47 162.6 0.4 1.7 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Herpes_LMP1 PF05297.6 EGD95413.1 - 3.1 6.6 19.5 5.5 5.8 13.5 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sin_N PF04801.8 EGD95414.1 - 4.7e-30 104.7 1.8 1.3e-28 100.0 1.2 2.0 1 1 0 1 1 1 1 Sin-like protein conserved region RNA_pol PF00940.14 EGD95415.1 - 4.8e-164 545.6 0.0 7.9e-164 544.9 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EGD95415.1 - 1.6e-79 267.5 0.5 2.5e-79 266.8 0.3 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Gag_spuma PF03276.9 EGD95417.1 - 0.16 10.3 2.3 0.18 10.0 1.6 1.0 1 0 0 1 1 1 0 Spumavirus gag protein SR-25 PF10500.4 EGD95417.1 - 0.17 11.2 9.6 0.19 11.1 6.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein T2SI PF02501.12 EGD95418.1 - 0.036 14.0 2.3 0.064 13.2 1.6 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I Radical_SAM PF04055.16 EGD95419.1 - 3.8e-09 36.9 0.0 5.5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EGD95419.1 - 2.4e-06 27.7 0.0 4.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EGD95419.1 - 0.0007 19.6 0.1 0.0016 18.4 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fructosamin_kin PF03881.9 EGD95420.1 - 7.2e-31 107.2 0.0 8.7e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EGD95420.1 - 0.0085 15.8 0.1 0.013 15.1 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Nudix_N PF12535.3 EGD95420.1 - 0.059 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal WD40 PF00400.27 EGD95421.1 - 1.8e-08 33.9 4.5 0.00045 19.9 0.0 6.2 7 0 0 7 7 7 1 WD domain, G-beta repeat DUF676 PF05057.9 EGD95421.1 - 1.6e-05 24.3 0.0 7.5e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGD95421.1 - 0.00068 19.2 0.1 0.0034 17.0 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGD95421.1 - 0.029 14.2 0.0 0.084 12.7 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 EGD95422.1 - 1.3e-11 43.8 25.8 4.5e-07 28.9 2.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF92 PF01940.11 EGD95423.1 - 1.2e-61 207.7 5.7 1.6e-61 207.3 4.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 TPR_2 PF07719.12 EGD95425.1 - 2.8e-05 23.7 0.0 0.0085 15.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGD95425.1 - 0.0009 18.8 0.0 0.0023 17.5 0.0 1.8 1 1 0 1 1 1 1 TPR repeat TPR_12 PF13424.1 EGD95425.1 - 0.022 14.6 0.1 1.9 8.4 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGD95425.1 - 0.064 12.9 0.0 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGD95425.1 - 0.13 12.9 0.0 16 6.3 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Methyltransf_33 PF10017.4 EGD95426.1 - 3.5e-28 98.0 0.0 6.6e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EGD95426.1 - 1.4e-19 70.4 4.9 1.6e-18 66.9 3.4 2.1 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EGD95426.1 - 2.6e-06 27.7 3.4 6.8e-06 26.4 1.5 2.3 2 1 0 2 2 2 1 DinB superfamily Methyltransf_25 PF13649.1 EGD95426.1 - 0.1 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Aldedh PF00171.17 EGD95428.1 - 5e-133 443.8 0.0 5.6e-133 443.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGD95428.1 - 3.7e-07 29.2 0.2 5.3e-06 25.4 0.2 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Nop25 PF09805.4 EGD95429.1 - 0.014 15.4 6.4 0.042 13.9 4.4 1.7 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Lipase_GDSL_2 PF13472.1 EGD95430.1 - 2.3e-08 34.3 0.1 7.5e-08 32.7 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGD95430.1 - 8.4e-08 32.3 0.1 3e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TFIIA_gamma_N PF02268.11 EGD95431.1 - 2.1e-26 91.2 0.2 3e-26 90.7 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EGD95431.1 - 1.8e-25 88.5 3.0 2.5e-25 88.0 2.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit CENP-B_dimeris PF09026.5 EGD95433.1 - 0.08 13.1 1.3 0.14 12.4 0.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Hexokinase_1 PF00349.16 EGD95434.1 - 3.3e-27 95.1 0.0 7.6e-24 84.1 0.0 3.1 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EGD95434.1 - 1.5e-24 86.5 0.0 1.7e-22 79.8 0.0 2.2 2 0 0 2 2 2 2 Hexokinase SR-25 PF10500.4 EGD95434.1 - 0.022 14.2 1.4 0.037 13.5 0.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GILT PF03227.11 EGD95435.1 - 5.2e-10 39.1 3.1 7e-10 38.7 0.3 2.6 1 1 1 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Carla_C4 PF01623.12 EGD95436.1 - 7.8 6.3 8.1 0.22 11.2 1.0 1.9 1 1 1 2 2 2 0 Carlavirus putative nucleic acid binding protein MFS_1 PF07690.11 EGD95437.1 - 3.3e-32 111.5 24.9 3.3e-32 111.5 17.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EGD95437.1 - 0.13 12.1 7.5 1.8 8.3 0.3 2.8 2 0 0 2 2 2 0 MFS_1 like family Spc97_Spc98 PF04130.8 EGD95438.1 - 2.3e-76 257.2 0.0 3.7e-76 256.6 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3459 PF11941.3 EGD95438.1 - 0.014 15.5 0.1 0.043 13.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) ThiF PF00899.16 EGD95439.1 - 6.9e-54 181.3 0.0 4.2e-32 110.8 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 EGD95439.1 - 1.2e-39 133.7 4.5 2.2e-26 91.2 0.3 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 EGD95439.1 - 6.8e-37 126.4 0.0 1.5e-36 125.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 EGD95439.1 - 4e-25 86.9 1.6 2.5e-21 74.7 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Resolvase PF00239.16 EGD95439.1 - 0.13 12.1 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Resolvase, N terminal domain GST_N_2 PF13409.1 EGD95440.1 - 6.8e-22 77.2 0.0 1.5e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD95440.1 - 5.5e-13 48.5 0.0 1.2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGD95440.1 - 2e-06 27.9 0.1 0.00011 22.3 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD95440.1 - 4.8e-05 23.2 0.0 0.00014 21.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD95440.1 - 0.0069 16.8 0.0 0.017 15.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.22 EGD95441.1 - 1.5e-65 216.9 5.0 2.5e-22 78.3 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EGD95441.1 - 8.3e-24 83.5 5.8 2.1e-13 50.2 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EGD95441.1 - 2.2e-20 70.3 6.7 3.6e-05 22.7 0.7 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EGD95441.1 - 8.2e-16 57.3 2.5 9.7e-07 28.3 0.1 3.5 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EGD95441.1 - 2.4e-15 54.9 10.7 6.5e-05 22.4 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGD95441.1 - 2.9e-15 54.8 12.5 6.6e-06 25.2 1.0 4.4 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 EGD95441.1 - 8.4e-10 38.6 0.2 0.00015 21.7 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EGD95441.1 - 0.00082 19.0 4.1 0.24 11.1 0.3 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EGD95441.1 - 0.0029 17.2 0.1 2.8 7.6 0.0 2.6 2 0 0 2 2 2 2 EF hand Cyclin_N PF00134.18 EGD95442.1 - 5.9e-12 45.2 0.1 9.3e-12 44.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1772 PF08592.6 EGD95442.1 - 0.16 11.7 4.9 0.13 11.9 2.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF4452 PF14618.1 EGD95443.1 - 5.5e-64 214.9 3.2 5.5e-64 214.9 2.2 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4452) Rubella_E2 PF05749.6 EGD95443.1 - 2.3 7.3 10.9 0.08 12.1 2.7 1.9 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 SelP_N PF04592.9 EGD95443.1 - 7.3 5.9 22.1 6.2 6.1 13.8 1.8 2 0 0 2 2 2 0 Selenoprotein P, N terminal region AMP-binding_C_2 PF14535.1 EGD95444.1 - 0.1 12.6 1.8 0.13 12.2 1.3 1.2 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Chal_sti_synt_C PF02797.10 EGD95446.1 - 1.4e-18 67.2 0.0 2.6e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.14 EGD95446.1 - 2.4e-16 59.6 0.1 3.8e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III_C PF08541.5 EGD95446.1 - 0.00013 21.9 0.0 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AMP-binding PF00501.23 EGD95448.1 - 1.5e-203 675.8 0.1 1.1e-72 244.7 0.0 4.2 3 1 1 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EGD95448.1 - 7.5e-57 192.4 0.0 1.1e-20 73.6 0.0 4.4 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 EGD95448.1 - 4.9e-35 119.6 5.0 3.9e-12 46.2 0.0 4.4 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD95448.1 - 2.3e-13 50.8 0.0 0.00018 22.3 0.0 3.8 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EGD95449.1 - 2.2e-14 52.9 33.8 7.5e-11 41.3 17.0 4.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SNARE PF05739.14 EGD95450.1 - 8.7e-15 54.1 1.2 8.7e-15 54.1 0.9 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EGD95450.1 - 0.011 15.8 1.4 0.38 10.9 0.1 2.5 2 0 0 2 2 2 0 Syntaxin Spectrin PF00435.16 EGD95450.1 - 0.088 13.0 1.5 0.22 11.8 0.1 2.1 2 0 0 2 2 2 0 Spectrin repeat Not3 PF04065.10 EGD95450.1 - 0.091 12.0 0.7 2.4 7.3 0.1 2.1 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component TPR_MLP1_2 PF07926.7 EGD95450.1 - 0.34 10.6 3.0 0.29 10.8 0.5 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-TRAF PF02176.13 EGD95451.1 - 2.7e-10 40.4 35.1 6.7e-06 26.3 5.5 4.7 1 1 4 5 5 5 4 TRAF-type zinc finger zf-RING_2 PF13639.1 EGD95451.1 - 2.2e-06 27.4 15.2 2.2e-06 27.4 10.5 4.0 3 1 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EGD95451.1 - 0.00012 21.6 10.0 0.0006 19.4 7.0 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EGD95451.1 - 0.00016 21.3 13.1 0.00016 21.3 9.1 4.5 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD95451.1 - 0.00059 19.5 14.2 0.00059 19.5 9.8 3.5 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGD95451.1 - 0.0015 18.5 15.3 0.0015 18.5 10.6 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD95451.1 - 0.01 15.4 15.1 0.01 15.4 10.5 4.0 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGD95451.1 - 0.011 15.6 14.9 0.011 15.6 10.4 3.3 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING Sina PF03145.11 EGD95451.1 - 0.019 14.6 18.5 0.055 13.1 0.3 2.9 1 1 1 2 2 2 0 Seven in absentia protein family TSC22 PF01166.13 EGD95451.1 - 0.065 13.1 0.4 5 7.1 0.1 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family Fmp27_WPPW PF10359.4 EGD95451.1 - 0.078 11.3 0.1 0.11 10.8 0.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2730 PF10805.3 EGD95451.1 - 0.25 11.0 3.2 1.4 8.6 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Het-C PF07217.6 EGD95453.1 - 5.4e-280 929.8 0.0 6.5e-280 929.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Ank_2 PF12796.2 EGD95456.1 - 3.2e-54 181.2 0.1 1e-13 51.4 0.0 8.5 6 1 2 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EGD95456.1 - 2.7e-41 137.3 2.3 1.5e-06 27.7 0.1 12.1 13 1 0 13 13 13 6 Ankyrin repeat Ank_4 PF13637.1 EGD95456.1 - 3e-41 139.0 3.5 1.5e-06 28.5 0.0 11.6 10 2 2 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD95456.1 - 2.9e-37 122.9 3.5 0.0004 20.3 0.1 13.3 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.1 EGD95456.1 - 6.4e-34 115.2 5.2 3.3e-05 23.9 0.0 11.6 11 0 0 11 11 11 5 Ankyrin repeats (many copies) HEM4 PF02602.10 EGD95456.1 - 0.047 12.9 0.0 12 5.0 0.0 2.8 3 0 0 3 3 3 0 Uroporphyrinogen-III synthase HemD IBN_N PF03810.14 EGD95457.1 - 7.6e-11 41.7 0.6 7e-08 32.2 0.0 3.4 2 1 1 3 3 3 2 Importin-beta N-terminal domain Xpo1 PF08389.7 EGD95457.1 - 1.8e-05 24.6 0.3 0.00075 19.4 0.1 3.5 3 1 0 3 3 3 1 Exportin 1-like protein CAS_CSE1 PF03378.10 EGD95457.1 - 0.0011 17.3 0.0 0.0041 15.4 0.0 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Proteasom_PSMB PF10508.4 EGD95457.1 - 0.015 13.5 0.5 0.081 11.1 0.0 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit TraG_N PF07916.6 EGD95457.1 - 0.041 12.3 0.0 0.086 11.2 0.0 1.4 1 0 0 1 1 1 0 TraG-like protein, N-terminal region KSR1-SAM PF13543.1 EGD95457.1 - 0.07 12.9 0.2 9 6.1 0.0 2.8 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 HORMA PF02301.13 EGD95459.1 - 2.6e-22 79.3 0.0 3.4e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 HORMA domain IBR PF01485.16 EGD95460.1 - 1e-10 41.3 29.5 6.1e-08 32.4 4.8 3.6 3 0 0 3 3 3 3 IBR domain Pkinase PF00069.20 EGD95461.1 - 5.6e-13 48.6 0.0 3.9e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95461.1 - 0.003 16.6 0.1 0.026 13.6 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Kdo PF06293.9 EGD95461.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_7 PF13508.1 EGD95463.1 - 0.00015 21.8 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD95463.1 - 0.0019 18.0 0.0 0.0054 16.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD95463.1 - 0.0089 16.0 0.1 0.036 14.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGD95463.1 - 0.07 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 EGD95463.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2036 PF09724.4 EGD95464.1 - 6.2e-24 84.7 0.1 1.6e-23 83.4 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Anp1 PF03452.9 EGD95465.1 - 4.6e-119 396.5 0.0 4.6e-119 396.5 0.0 2.2 2 1 0 2 2 2 1 Anp1 DUF1675 PF07897.6 EGD95465.1 - 0.0058 16.5 20.1 0.0074 16.1 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1675) DUF2146 PF10220.4 EGD95465.1 - 3 5.7 18.8 5.5 4.8 13.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) tRNA_bind PF01588.15 EGD95466.1 - 1.3e-20 73.0 0.0 4.9e-19 67.9 0.0 2.5 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EGD95466.1 - 2.8e-10 40.5 0.0 6.6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGD95466.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RR_TM4-6 PF06459.7 EGD95466.1 - 0.6 9.9 4.2 0.99 9.2 2.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp PF00026.18 EGD95467.1 - 9.4e-64 215.6 0.1 1.1e-63 215.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGD95467.1 - 1.5e-08 35.0 0.4 0.00017 21.9 0.1 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EGD95467.1 - 6.4e-05 22.9 0.0 0.00079 19.4 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EGD95467.1 - 0.00043 20.0 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease FAD_binding_4 PF01565.18 EGD95467.1 - 0.085 12.3 1.0 0.74 9.2 0.0 2.9 4 0 0 4 4 4 0 FAD binding domain RVP PF00077.15 EGD95467.1 - 0.098 12.5 0.3 7.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease TAXi_C PF14541.1 EGD95467.1 - 0.1 12.1 0.2 1.3 8.5 0.1 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal ParA PF10609.4 EGD95468.1 - 2.4e-35 120.2 0.0 4.3e-35 119.4 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGD95468.1 - 3.9e-17 62.2 0.0 5.5e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGD95468.1 - 8.7e-07 29.0 0.0 6.6e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EGD95468.1 - 6.2e-06 25.4 0.3 0.00036 19.6 0.0 2.6 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EGD95468.1 - 0.00018 20.6 0.0 0.00035 19.7 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 EGD95468.1 - 0.0034 16.9 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGD95468.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGD95468.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EGD95468.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EGD95468.1 - 0.069 13.9 0.0 0.1 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGD95468.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zn_Tnp_IS1595 PF12760.2 EGD95468.1 - 0.093 12.5 0.1 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain RNA_helicase PF00910.17 EGD95468.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EGD95468.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGD95468.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PEMT PF04191.8 EGD95469.1 - 2.3e-58 194.8 11.3 9.7e-36 122.0 0.6 3.3 3 0 0 3 3 3 2 Phospholipid methyltransferase RNase_PH PF01138.16 EGD95470.1 - 2.5e-26 92.5 0.0 4.9e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Lactamase_B PF00753.22 EGD95471.1 - 7.3e-10 38.8 0.0 1.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGD95471.1 - 0.00024 20.7 0.1 0.0005 19.6 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Bim_N PF06773.6 EGD95472.1 - 0.13 12.0 0.2 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Bim protein N-terminus MFS_1 PF07690.11 EGD95474.1 - 3.3e-33 114.8 38.8 1.4e-24 86.5 8.6 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.8 EGD95474.1 - 0.0058 14.8 1.8 0.01 14.0 1.2 1.4 1 1 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 EGD95474.1 - 3.8 5.4 10.1 0.41 8.6 0.5 2.8 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ProRS-C_1 PF09180.6 EGD95475.1 - 1.5e-21 76.1 3.9 3.1e-21 75.0 2.3 1.9 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EGD95475.1 - 4.5e-21 75.1 0.1 7.1e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGD95475.1 - 7.6e-12 45.0 0.0 2.7e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain Cpn60_TCP1 PF00118.19 EGD95476.1 - 5.8e-143 477.0 14.6 6.7e-143 476.8 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 EGD95477.1 - 1.6e-20 72.1 12.6 1.1e-06 28.2 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EGD95477.1 - 0.00013 20.2 1.1 0.00024 19.3 0.1 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 S1 PF00575.18 EGD95478.1 - 7.2e-82 269.5 41.5 7.3e-17 61.2 0.2 12.6 12 0 0 12 12 12 11 S1 RNA binding domain TPR_16 PF13432.1 EGD95478.1 - 4e-07 30.5 0.0 0.74 10.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD95478.1 - 2.3e-06 27.7 0.1 0.88 10.3 0.1 4.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGD95478.1 - 5.9e-06 26.5 0.1 0.051 13.9 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.9 EGD95478.1 - 0.0018 18.0 12.9 0.019 14.7 0.0 4.6 2 2 1 4 4 4 2 Suppressor of forked protein (Suf) PPR PF01535.15 EGD95478.1 - 0.12 12.4 0.0 33 4.7 0.0 3.3 2 1 0 2 2 2 0 PPR repeat DUF3827 PF12877.2 EGD95480.1 - 0.77 7.7 8.1 0.95 7.4 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) NPR3 PF03666.8 EGD95480.1 - 2.5 6.5 8.3 2.9 6.3 5.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.9 EGD95480.1 - 6 4.7 11.2 7 4.5 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 EGD95480.1 - 7 6.4 8.5 10 5.9 5.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.5 EGD95480.1 - 7.4 4.8 8.2 7.8 4.7 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Phage_lysozyme PF00959.14 EGD95481.1 - 7.2e-12 45.5 0.0 1e-11 45.1 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme UreD PF01774.12 EGD95482.1 - 2.4e-51 174.1 0.0 4.4e-51 173.3 0.0 1.5 1 1 0 1 1 1 1 UreD urease accessory protein STAG PF08514.6 EGD95483.1 - 8.9e-37 125.3 0.3 8.9e-37 125.3 0.2 2.3 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.1 EGD95483.1 - 0.0031 17.7 0.1 0.59 10.4 0.1 3.5 2 1 0 3 3 3 1 HEAT repeats DUF3573 PF12097.3 EGD95483.1 - 0.081 11.5 0.2 0.24 9.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF422 PF04240.7 EGD95483.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF422) GFA PF04828.9 EGD95484.1 - 1.9e-15 56.5 3.3 2.8e-15 56.0 2.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Acatn PF13000.2 EGD95485.1 - 2.2e-147 491.8 22.3 6.8e-80 269.1 6.5 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.5 EGD95486.1 - 4.2e-27 94.2 0.1 2.4e-26 91.7 0.0 2.0 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component MreB_Mbl PF06723.8 EGD95488.1 - 0.19 10.2 0.2 0.27 9.7 0.2 1.1 1 0 0 1 1 1 0 MreB/Mbl protein DFP PF04127.10 EGD95491.1 - 7.7e-13 48.4 0.0 0.00022 20.9 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Polysacc_deac_1 PF01522.16 EGD95492.1 - 4.5e-20 71.5 0.0 7.5e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGD95492.1 - 0.0049 15.8 0.0 0.008 15.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.4 EGD95492.1 - 0.098 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF4388 PF14332.1 EGD95492.1 - 0.12 12.1 0.0 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) DEAD PF00270.24 EGD95493.1 - 1.5e-41 141.7 0.0 2.5e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD95493.1 - 8.7e-22 76.7 0.1 1.8e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGD95493.1 - 2.4e-05 23.3 0.0 3.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 EGD95493.1 - 0.02 13.3 0.0 1.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) ResIII PF04851.10 EGD95493.1 - 0.033 14.0 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF162 PF02589.10 EGD95493.1 - 0.11 12.0 0.0 0.76 9.2 0.0 2.4 4 0 0 4 4 4 0 Uncharacterised ACR, YkgG family COG1556 GDA1_CD39 PF01150.12 EGD95493.1 - 0.11 10.9 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Glyoxal_oxid_N PF07250.6 EGD95494.1 - 1.5e-40 138.7 0.0 4.4e-39 134.0 0.0 2.4 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EGD95494.1 - 4.7e-22 77.9 0.1 1.2e-21 76.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.14 EGD95494.1 - 0.0002 21.2 21.7 0.0002 21.2 15.0 2.3 2 0 0 2 2 2 1 Chitin recognition protein RCC1_2 PF13540.1 EGD95494.1 - 0.048 13.3 0.1 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Fumble PF03630.9 EGD95495.1 - 1.9e-136 454.4 2.2 2.2e-135 450.9 1.5 2.0 1 1 0 1 1 1 1 Fumble GPI2 PF06432.6 EGD95496.1 - 3.8e-115 384.0 6.4 4.8e-115 383.7 4.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF605 PF04652.11 EGD95496.1 - 3 7.1 10.9 3.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Vta1 like Miff PF05644.6 EGD95497.1 - 0.0007 19.3 6.7 0.0007 19.3 4.7 1.7 1 1 1 2 2 2 1 Mitochondrial and peroxisomal fission factor Mff DUF1618 PF07762.9 EGD95497.1 - 0.027 14.6 0.1 0.039 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1618) DUF1510 PF07423.6 EGD95497.1 - 0.39 10.0 12.3 0.97 8.7 7.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) AIF_C PF14721.1 EGD95497.1 - 1.1 9.4 6.8 9.3 6.4 3.7 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pox_Ag35 PF03286.9 EGD95497.1 - 1.4 8.3 19.6 0.16 11.5 9.5 1.9 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Ycf1 PF05758.7 EGD95497.1 - 3.1 5.3 10.2 3.6 5.1 7.0 1.1 1 0 0 1 1 1 0 Ycf1 ORC6 PF05460.8 EGD95497.1 - 3.7 6.5 14.6 2.9 6.8 9.3 1.3 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF4337 PF14235.1 EGD95497.1 - 9.9 5.9 8.6 18 5.1 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Glyco_hydro_18 PF00704.23 EGD95501.1 - 2.3e-19 70.0 0.3 7.3e-18 65.1 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 AA_permease_2 PF13520.1 EGD95504.1 - 4e-45 154.1 55.3 4.9e-45 153.8 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD95504.1 - 1.3e-23 83.1 48.7 1.6e-23 82.8 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD95506.1 - 1e-44 152.7 47.2 1.3e-44 152.4 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD95506.1 - 1.2e-29 102.9 42.1 1.7e-29 102.5 29.1 1.0 1 0 0 1 1 1 1 Amino acid permease Dynamin_N PF00350.18 EGD95507.1 - 3.2e-26 92.1 0.0 6.9e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGD95507.1 - 9.5e-16 57.4 1.6 8.8e-15 54.2 0.0 2.7 3 0 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.18 EGD95507.1 - 0.0023 17.8 0.0 0.014 15.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD95507.1 - 0.054 13.9 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein GED PF02212.13 EGD95507.1 - 0.37 10.7 9.6 0.33 10.8 0.5 4.5 4 1 1 5 5 5 0 Dynamin GTPase effector domain 5_nucleotid_C PF02872.13 EGD95510.1 - 1.4e-30 106.2 0.0 2.2e-29 102.4 0.0 2.2 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EGD95510.1 - 3.4e-06 26.5 1.3 1.2e-05 24.7 0.9 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FG-GAP PF01839.18 EGD95510.1 - 0.29 10.8 4.0 1.2 8.9 2.8 2.1 1 0 0 1 1 1 0 FG-GAP repeat TMEM154 PF15102.1 EGD95511.1 - 0.0016 18.2 0.0 0.0018 18.0 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family Protocadherin PF08374.6 EGD95511.1 - 0.0065 16.1 0.0 0.0075 15.9 0.0 1.1 1 0 0 1 1 1 1 Protocadherin DUF3357 PF11837.3 EGD95511.1 - 0.02 14.7 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DICT PF10069.4 EGD95511.1 - 0.093 12.2 0.0 2.9 7.4 0.0 2.0 2 0 0 2 2 2 0 Sensory domain found in DIguanylate Cyclases & Two-component systems Kinetochor_Ybp2 PF08568.5 EGD95511.1 - 0.13 10.4 0.0 0.15 10.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin DUF1049 PF06305.6 EGD95511.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Aldedh PF00171.17 EGD95512.1 - 7.4e-152 505.8 0.1 8.3e-152 505.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DMRL_synthase PF00885.14 EGD95512.1 - 0.092 12.4 0.0 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase Glyco_trans_2_3 PF13632.1 EGD95514.1 - 0.0029 17.3 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Gln-synt_C PF00120.19 EGD95518.1 - 2.4e-42 144.8 0.0 4.7e-42 143.9 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EGD95518.1 - 7e-26 91.3 0.0 1.3e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 EGD95519.1 - 2.6e-36 125.0 22.8 2.6e-36 125.0 15.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD95519.1 - 4.5e-13 48.5 11.4 4.5e-13 48.5 7.9 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EGD95519.1 - 0.00024 19.4 3.3 0.00039 18.7 2.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0016 PF01169.14 EGD95522.1 - 2.2e-39 133.4 25.3 3.2e-21 75.2 5.1 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2208 PF09973.4 EGD95522.1 - 0.0047 16.1 0.0 0.0085 15.3 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) DUF4614 PF15391.1 EGD95522.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) gp32 PF08804.5 EGD95523.1 - 0.0083 16.2 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 gp32 DNA binding protein like Myb_DNA-binding PF00249.26 EGD95524.1 - 0.00091 19.2 0.1 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Annexin PF00191.15 EGD95525.1 - 3.3e-13 49.3 6.7 0.0049 16.7 0.1 4.7 4 1 0 4 4 4 4 Annexin Ribosomal_L21e PF01157.13 EGD95526.1 - 4.5e-27 93.7 3.9 4.5e-27 93.7 2.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Ter PF05472.6 EGD95526.1 - 0.0085 15.2 0.5 0.01 14.9 0.4 1.1 1 0 0 1 1 1 1 DNA replication terminus site-binding protein (Ter protein) Nexin_C PF08628.7 EGD95526.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Sorting nexin C terminal Ribosomal_S4 PF00163.14 EGD95527.1 - 1.5e-30 105.4 1.5 2.5e-30 104.7 0.7 1.7 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EGD95527.1 - 8e-13 47.6 1.5 8e-13 47.6 1.1 2.3 3 0 0 3 3 3 1 S4 domain Amidoligase_2 PF12224.3 EGD95530.1 - 6.6e-13 48.8 0.0 2.2e-06 27.5 0.0 3.0 2 1 0 2 2 2 2 Putative amidoligase enzyme 4HBT_3 PF13622.1 EGD95530.1 - 4.6 6.8 7.1 0.36 10.5 1.2 1.9 2 0 0 2 2 2 0 Thioesterase-like superfamily DUF946 PF06101.6 EGD95532.1 - 4.1e-10 38.2 0.9 2.3e-08 32.4 0.3 2.0 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) NPP1 PF05630.6 EGD95532.1 - 0.068 12.9 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Septin PF00735.13 EGD95533.1 - 7.3e-34 117.0 0.0 1.2e-13 50.7 0.0 3.2 2 1 1 3 3 3 3 Septin Miro PF08477.8 EGD95533.1 - 0.011 16.2 0.0 0.03 14.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein TEX19 PF15553.1 EGD95533.1 - 0.024 14.4 1.6 0.054 13.3 1.1 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 AAA_23 PF13476.1 EGD95533.1 - 0.097 12.9 0.2 0.29 11.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EGD95533.1 - 0.41 10.4 2.1 0.58 9.9 0.0 2.4 3 0 0 3 3 3 0 Dynamin family Mito_carr PF00153.22 EGD95534.1 - 2e-76 251.8 1.5 1.3e-24 85.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1049 PF06305.6 EGD95534.1 - 0.04 13.4 0.0 5.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) SecE PF00584.15 EGD95537.1 - 4.3e-12 45.4 0.0 5.2e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_6 PF14259.1 EGD95538.1 - 7.5e-09 35.4 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD95538.1 - 1.6e-06 27.6 0.0 2.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD95538.1 - 0.0025 17.6 0.1 0.0052 16.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ndc1_Nup PF09531.5 EGD95538.1 - 1.2 7.4 6.3 1.5 7.1 4.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.9 EGD95538.1 - 1.7 8.3 16.9 3 7.4 11.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nucleo_P87 PF07267.6 EGD95538.1 - 2.2 6.8 10.8 3.7 6.1 7.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BAF1_ABF1 PF04684.8 EGD95538.1 - 5.8 5.6 21.9 8.5 5.1 15.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RR_TM4-6 PF06459.7 EGD95538.1 - 5.9 6.6 13.3 11 5.7 9.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DHHW PF14286.1 EGD95538.1 - 6.1 6.0 9.5 9.7 5.3 6.6 1.2 1 0 0 1 1 1 0 DHHW protein FYDLN_acid PF09538.5 EGD95538.1 - 7.7 7.1 10.0 2.2 8.8 4.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) WD40 PF00400.27 EGD95539.1 - 4e-25 86.7 16.7 2e-06 27.4 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGD95539.1 - 6.4e-06 24.7 1.9 0.018 13.3 0.0 3.9 3 1 0 4 4 4 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 EGD95539.1 - 0.00057 20.0 3.2 0.35 11.2 0.1 4.4 4 0 0 4 4 4 1 PQQ-like domain Nucleoporin_N PF08801.6 EGD95539.1 - 0.068 11.9 0.8 1.1 7.9 0.1 2.9 3 1 0 3 3 3 0 Nup133 N terminal like PD40 PF07676.7 EGD95539.1 - 0.28 10.8 0.0 0.28 10.8 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat CENP-T PF15511.1 EGD95539.1 - 0.36 10.0 8.4 0.56 9.3 5.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EGD95539.1 - 5.9 4.6 15.2 8 4.2 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family PX PF00787.19 EGD95540.1 - 1.3e-26 92.6 0.2 1.5e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 EGD95540.1 - 0.059 12.4 0.0 0.073 12.1 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus Myb_DNA-bind_6 PF13921.1 EGD95541.1 - 1.1e-14 54.2 0.2 1.6e-06 28.0 0.0 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD95541.1 - 5.8e-10 39.0 0.2 0.00012 22.0 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain RasGEF PF00617.14 EGD95543.1 - 0.0013 18.4 0.0 0.055 13.1 0.0 2.6 1 1 1 2 2 2 2 RasGEF domain UPF0139 PF03669.8 EGD95544.1 - 3.2e-05 23.3 0.3 3.8e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DNA_pol_B PF00136.16 EGD95545.1 - 3.4e-92 309.6 0.2 6.8e-92 308.6 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGD95545.1 - 1.5e-19 70.0 0.0 3e-11 42.7 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EGD95545.1 - 6.6e-18 64.4 8.7 6.6e-18 64.4 6.0 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Slu7 PF11708.3 EGD95546.1 - 4.6e-79 265.5 17.3 4.6e-79 265.5 12.0 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EGD95546.1 - 0.0099 15.5 0.6 0.022 14.4 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGD95546.1 - 1.7 8.1 5.2 3.5 7.2 3.6 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Toxin_60 PF15607.1 EGD95546.1 - 2.3 8.3 10.9 0.55 10.2 1.3 3.1 2 1 1 3 3 3 0 Putative toxin 60 Ribosomal_L37e PF01907.14 EGD95547.1 - 8.9e-24 83.0 6.0 1.5e-23 82.3 4.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EGD95547.1 - 0.012 15.3 1.0 0.021 14.6 0.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon Ribosomal_S14 PF00253.16 EGD95547.1 - 2.6 7.4 7.0 0.36 10.2 0.2 2.4 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e DUF2348 PF09807.4 EGD95548.1 - 2.1e-07 30.3 0.1 0.00014 21.0 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 EGD95548.1 - 0.097 11.7 0.0 0.37 9.8 0.0 1.7 2 0 0 2 2 2 0 KaiC RdRP PF05183.7 EGD95549.1 - 2.8e-191 637.1 0.2 4.1e-191 636.6 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 EGD95549.1 - 0.0046 16.5 0.0 0.014 14.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease PF00324.16 EGD95550.1 - 1.2e-134 449.2 42.9 1.5e-134 448.9 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD95550.1 - 4.3e-36 124.3 46.3 5.4e-36 124.0 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease Sulfate_transp PF00916.15 EGD95551.1 - 1.2e-79 267.3 8.9 2e-79 266.5 6.2 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGD95551.1 - 3.9e-30 103.3 2.5 3.9e-30 103.3 1.8 3.0 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGD95551.1 - 4.1e-08 32.6 0.0 8.4e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain FAD-oxidase_C PF02913.14 EGD95552.1 - 4.7e-57 193.1 0.0 6.2e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGD95552.1 - 4.5e-35 120.1 0.1 1.4e-34 118.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Ribosomal_S4e PF00900.15 EGD95553.1 - 8.3e-32 108.6 0.3 1.6e-31 107.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EGD95553.1 - 5.8e-19 67.6 4.9 1.2e-18 66.6 3.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EGD95553.1 - 6.2e-05 22.3 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EGD95553.1 - 0.011 15.4 0.9 0.011 15.4 0.6 3.1 4 0 0 4 4 4 0 KOW motif DUF3709 PF12493.3 EGD95554.1 - 0.052 13.2 0.2 0.093 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3709) MAT_Alpha1 PF04769.7 EGD95555.1 - 3e-31 108.3 0.0 4.8e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 DUF3525 PF12039.3 EGD95555.1 - 0.14 10.6 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) DUF3275 PF11679.3 EGD95555.1 - 0.33 10.5 4.5 0.56 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Glyco_hydro_72 PF03198.9 EGD95556.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase Exo_endo_phos_2 PF14529.1 EGD95557.1 - 1.9e-14 53.3 0.0 2.3e-13 49.8 0.0 2.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EGD95557.1 - 9.7e-12 45.3 0.0 1.7e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EGD95557.1 - 0.004 17.0 0.2 0.0097 15.8 0.1 1.6 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.10 EGD95558.1 - 7.2e-47 158.0 1.2 8.2e-47 157.9 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa I_LWEQ PF01608.12 EGD95559.1 - 5.4e-64 214.7 8.0 5.4e-64 214.7 5.5 5.5 5 1 0 6 6 6 1 I/LWEQ domain ANTH PF07651.11 EGD95559.1 - 4.3e-55 186.3 0.0 4.3e-55 186.3 0.0 2.8 2 1 0 2 2 2 1 ANTH domain Med15 PF09606.5 EGD95559.1 - 0.67 8.0 27.4 1.2 7.2 19.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FlaC_arch PF05377.6 EGD95559.1 - 8.6 6.3 11.8 6.5 6.7 0.1 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF2404 PF10296.4 EGD95560.1 - 4.2e-21 74.8 0.0 7.8e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Hemerythrin PF01814.18 EGD95561.1 - 1.7e-13 50.9 0.1 2.2e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain SKG6 PF08693.5 EGD95562.1 - 0.018 14.3 0.6 0.036 13.3 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mid2 PF04478.7 EGD95562.1 - 0.048 13.0 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF1510 PF07423.6 EGD95562.1 - 0.071 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Med12 PF09497.5 EGD95563.1 - 7.2e-28 96.3 0.1 2.4e-27 94.7 0.1 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 CIA30 PF08547.7 EGD95564.1 - 1.7e-37 128.7 0.0 4.2e-24 85.1 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SAICAR_synt PF01259.13 EGD95565.1 - 3.5e-84 281.7 0.0 4.4e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase DUF3439 PF11921.3 EGD95565.1 - 1.4 8.6 5.9 1.6 8.4 3.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Apc5 PF12862.2 EGD95566.1 - 5.7e-31 106.2 1.7 1e-30 105.3 0.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 EGD95566.1 - 3.7e-06 26.7 3.3 0.047 13.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGD95566.1 - 0.0035 17.6 2.9 0.029 14.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD95566.1 - 0.0047 17.5 0.3 0.97 10.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 EGD95566.1 - 0.027 14.4 0.1 0.18 11.7 0.0 2.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Cohesin_load PF10345.4 EGD95566.1 - 0.03 12.5 0.1 3.7 5.6 0.1 2.1 2 0 0 2 2 2 0 Cohesin loading factor TPR_7 PF13176.1 EGD95566.1 - 0.032 14.0 0.0 25 4.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGD95566.1 - 0.069 12.7 0.2 8.6 6.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGD95566.1 - 0.17 12.3 4.0 14 6.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3873 PF12989.2 EGD95566.1 - 0.18 11.9 2.1 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) SUI1 PF01253.17 EGD95567.1 - 4.9e-29 99.9 6.2 7e-29 99.4 4.3 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 EOS1 PF12326.3 EGD95568.1 - 5.8e-30 103.8 16.2 9.5e-25 86.9 8.1 2.2 1 1 1 2 2 2 2 N-glycosylation protein YesK PF14150.1 EGD95568.1 - 0.29 11.2 3.4 0.94 9.6 2.1 2.1 1 1 0 1 1 1 0 YesK-like protein MBA1 PF07961.6 EGD95569.1 - 3.3e-08 32.6 0.1 6.4e-08 31.7 0.1 1.4 1 1 0 1 1 1 1 MBA1-like protein SSF PF00474.12 EGD95570.1 - 4.5e-08 32.1 31.4 2.2e-07 29.8 21.8 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family RhoGAP PF00620.22 EGD95571.1 - 5e-48 162.5 0.0 1.2e-47 161.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EGD95571.1 - 7.6e-14 51.6 2.2 2e-13 50.3 0.2 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain HrpA_pilin PF09589.5 EGD95571.1 - 0.28 11.6 3.2 0.73 10.2 2.2 1.8 1 0 0 1 1 1 0 HrpA pilus formation protein DUF4407 PF14362.1 EGD95571.1 - 1.9 7.3 7.9 3.8 6.3 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABM PF03992.11 EGD95572.1 - 1.4e-13 50.7 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SchA_CurD PF04486.7 EGD95572.1 - 0.094 12.5 0.0 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 SchA/CurD like domain UPF0160 PF03690.8 EGD95575.1 - 0.059 12.7 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) AAA PF00004.24 EGD95579.1 - 2.3e-21 76.3 0.0 5.5e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGD95579.1 - 3.7e-05 24.5 2.4 0.00019 22.2 0.0 3.1 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.7 EGD95579.1 - 9.2e-05 21.5 0.0 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGD95579.1 - 0.00031 20.8 0.1 0.036 14.2 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EGD95579.1 - 0.00051 19.7 0.0 0.0019 17.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGD95579.1 - 0.00083 19.3 0.0 0.0028 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EGD95579.1 - 0.0037 17.5 0.0 0.0095 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGD95579.1 - 0.0049 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DEAD PF00270.24 EGD95579.1 - 0.059 12.8 0.0 3.4 7.1 0.0 2.3 1 1 0 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.16 EGD95579.1 - 0.082 12.0 0.1 0.23 10.5 0.1 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EGD95579.1 - 0.085 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EGD95579.1 - 0.099 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGD95579.1 - 0.13 12.0 0.5 0.47 10.2 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain L51_S25_CI-B8 PF05047.11 EGD95580.1 - 0.054 13.2 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Phospholip_B PF04916.8 EGD95581.1 - 0.012 13.8 0.0 0.013 13.6 0.0 1.1 1 0 0 1 1 1 0 Phospholipase B Nuc_rec_co-act PF08815.5 EGD95582.1 - 0.044 13.3 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Nuclear receptor coactivator DUF3304 PF11745.3 EGD95583.1 - 0.11 12.6 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3304) Pkinase PF00069.20 EGD95585.1 - 9.5e-05 21.6 0.1 0.00022 20.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 EGD95585.1 - 0.00094 18.2 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD95585.1 - 0.0023 17.6 0.1 0.0023 17.6 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EGD95585.1 - 0.022 14.0 0.0 0.057 12.7 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EGD95585.1 - 0.091 12.3 0.3 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase TMEM51 PF15345.1 EGD95588.1 - 0.28 10.8 3.6 0.31 10.6 2.5 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 APH PF01636.18 EGD95589.1 - 6.2e-11 42.4 0.0 1.3e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD95589.1 - 0.00064 19.3 0.0 0.0015 18.1 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3212 PF11486.3 EGD95589.1 - 0.055 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) MFS_1 PF07690.11 EGD95590.1 - 1.9e-45 155.1 43.8 1.9e-45 155.1 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD95590.1 - 0.00038 19.1 30.0 0.0026 16.4 20.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Radical_SAM PF04055.16 EGD95591.1 - 1.4e-23 83.9 0.1 2.7e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EGD95591.1 - 3.7e-22 78.1 0.0 1e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EGD95591.1 - 0.032 14.2 0.5 1.2 9.0 0.3 2.5 1 1 0 1 1 1 0 Flavodoxin Pro_dh PF01619.13 EGD95592.1 - 4.2e-39 134.3 3.0 5.7e-39 133.9 2.1 1.2 1 0 0 1 1 1 1 Proline dehydrogenase MAAL_N PF05034.8 EGD95592.1 - 0.044 13.5 0.1 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase N-terminus Aldedh PF00171.17 EGD95593.1 - 9.9e-98 327.4 0.0 1.1e-97 327.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OCD_Mu_crystall PF02423.10 EGD95594.1 - 2e-12 46.5 0.1 7.8e-06 24.8 0.2 2.9 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EGD95594.1 - 0.0004 20.4 0.0 0.012 15.6 0.0 2.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EGD95594.1 - 0.053 12.6 0.3 0.33 10.0 0.0 2.4 3 1 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rab_eff_C PF04698.7 EGD95594.1 - 0.11 10.6 0.2 0.18 9.9 0.2 1.2 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Zn_clus PF00172.13 EGD95595.1 - 1.7e-05 24.5 10.0 2.7e-05 23.9 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain USP8_interact PF08941.5 EGD95595.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 USP8 interacting Fungal_trans PF04082.13 EGD95595.1 - 0.57 9.0 2.8 3 6.6 0.1 2.6 3 0 0 3 3 3 0 Fungal specific transcription factor domain Amino_oxidase PF01593.19 EGD95596.1 - 6.8e-44 150.6 0.4 2.1e-42 145.7 0.3 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGD95596.1 - 1.6e-11 44.0 0.0 3.2e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD95596.1 - 1.7e-05 23.8 0.4 0.00023 20.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGD95596.1 - 3e-05 24.1 0.1 0.00091 19.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD95596.1 - 8e-05 22.9 0.1 0.00056 20.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD95596.1 - 0.00014 21.8 0.2 0.0085 15.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGD95596.1 - 0.00017 20.5 0.1 0.00025 20.0 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EGD95596.1 - 0.00032 19.8 0.9 0.00053 19.1 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGD95596.1 - 0.0019 16.7 0.2 0.0029 16.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EGD95596.1 - 0.0037 16.2 0.1 0.023 13.6 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EGD95596.1 - 0.0083 15.0 0.2 0.012 14.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EGD95596.1 - 0.013 15.2 0.1 0.021 14.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EGD95596.1 - 0.016 14.9 1.0 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EGD95596.1 - 0.053 12.6 0.1 0.087 11.9 0.1 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 EGD95596.1 - 0.22 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LEA_6 PF10714.4 EGD95597.1 - 0.2 11.5 3.5 0.34 10.7 0.9 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 PVL_ORF50 PF07768.6 EGD95597.1 - 0.27 11.2 1.3 0.48 10.4 0.9 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family Metallophos_2 PF12850.2 EGD95598.1 - 8.7e-07 28.9 0.0 3.6e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2183 PF09949.4 EGD95599.1 - 5.3e-32 109.7 0.0 1.4e-31 108.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.1 EGD95599.1 - 0.016 15.2 0.1 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain RPAP1_N PF08621.5 EGD95599.1 - 0.079 12.5 1.3 0.17 11.4 0.9 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal PI31_Prot_N PF11566.3 EGD95600.1 - 7.1e-24 84.1 0.0 9.3e-24 83.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EGD95600.1 - 3.6e-17 62.7 13.4 3.6e-17 62.7 9.3 2.4 2 0 0 2 2 2 1 PI31 proteasome regulator Metallophos PF00149.23 EGD95601.1 - 3.1e-44 150.7 0.8 3.8e-44 150.4 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short_C2 PF13561.1 EGD95602.1 - 3.6e-32 112.0 0.1 4.2e-32 111.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD95602.1 - 1.4e-29 103.1 0.7 1.8e-29 102.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD95602.1 - 2.8e-11 43.4 0.2 4e-11 42.9 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGD95602.1 - 0.00057 19.9 0.7 0.0038 17.2 0.5 2.0 2 0 0 2 2 2 1 NADH(P)-binding Pyr_redox PF00070.22 EGD95602.1 - 0.0057 17.0 0.5 0.014 15.7 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EGD95602.1 - 0.0063 16.6 0.3 0.011 15.8 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 EGD95602.1 - 0.014 14.4 0.2 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 EGD95602.1 - 0.016 14.3 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.5 EGD95602.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EGD95602.1 - 0.055 12.8 1.1 1.4 8.2 0.7 2.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3112 PF11309.3 EGD95603.1 - 7.2e-45 152.6 15.8 8.2e-45 152.4 1.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) PepSY_TM_3 PF13706.1 EGD95603.1 - 0.19 11.1 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 0 PepSY-associated TM helix TPR_11 PF13414.1 EGD95604.1 - 1.8e-14 53.1 1.5 1.2e-12 47.2 0.2 2.4 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EGD95604.1 - 8.2e-08 31.5 0.6 0.00029 20.3 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD95604.1 - 1.5e-05 24.7 0.3 4e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD95604.1 - 7.2e-05 22.2 0.1 0.087 12.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGD95604.1 - 8.3e-05 22.2 3.2 0.029 14.2 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat ELH PF02323.10 EGD95604.1 - 0.00094 18.3 0.4 0.0016 17.6 0.0 1.4 2 0 0 2 2 2 1 Egg-laying hormone precursor Apc3 PF12895.2 EGD95604.1 - 0.0041 17.2 0.4 0.0086 16.1 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4406 PF14359.1 EGD95604.1 - 0.014 15.4 0.3 1.5 8.9 0.0 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4406) TPR_14 PF13428.1 EGD95604.1 - 0.022 15.3 1.0 1.2 9.9 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGD95604.1 - 0.069 13.5 0.2 0.28 11.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 EGD95605.1 - 9.4e-28 97.0 0.0 1.4e-26 93.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95605.1 - 2.1e-13 49.9 0.0 2.5e-12 46.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase HAD_2 PF13419.1 EGD95606.1 - 6.6e-13 49.2 0.0 1e-12 48.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD95606.1 - 5.4e-05 22.8 0.1 0.00056 19.5 0.0 2.6 4 0 0 4 4 4 1 HAD-hyrolase-like Hydrolase PF00702.21 EGD95606.1 - 0.00014 22.3 0.0 0.00055 20.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase WD40 PF00400.27 EGD95610.1 - 6.1e-06 25.9 14.1 0.16 11.8 0.5 7.4 8 1 0 8 8 8 3 WD domain, G-beta repeat Nucleoporin_FG PF13634.1 EGD95611.1 - 1.2e-10 41.5 83.3 1.7e-05 25.0 25.9 3.1 1 1 1 2 2 2 2 Nucleoporin FG repeat region Lectin_N PF03954.9 EGD95611.1 - 0.019 14.3 0.4 0.46 9.8 0.0 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF724 PF05266.9 EGD95611.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.7 EGD95611.1 - 0.13 12.0 0.8 5.2 6.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cpn10 PF00166.16 EGD95613.1 - 3.9e-26 90.8 0.0 4.5e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Fip1 PF05182.8 EGD95614.1 - 8.5e-22 76.1 1.7 1.5e-21 75.3 1.2 1.4 1 0 0 1 1 1 1 Fip1 motif Daxx PF03344.10 EGD95614.1 - 0.8 8.1 6.3 1 7.7 4.4 1.1 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 EGD95614.1 - 1.1 8.7 8.2 2 7.9 5.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF2890 PF11081.3 EGD95614.1 - 1.1 9.2 6.8 2 8.4 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Prothymosin PF03247.9 EGD95614.1 - 1.4 9.1 16.2 2.4 8.3 11.2 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF605 PF04652.11 EGD95614.1 - 2.1 7.6 14.4 3 7.1 10.0 1.2 1 0 0 1 1 1 0 Vta1 like Lin-8 PF03353.10 EGD95614.1 - 2.9 7.1 6.9 4.1 6.5 4.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.7 EGD95614.1 - 4.3 5.1 11.7 5.3 4.8 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family XAP5 PF04921.9 EGD95615.1 - 6e-43 147.1 0.0 3.6e-42 144.5 0.0 2.1 2 1 0 2 2 2 1 XAP5, circadian clock regulator zf-RING_5 PF14634.1 EGD95616.1 - 1.3e-08 34.4 8.0 2.9e-08 33.2 5.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGD95616.1 - 3.7e-05 23.6 3.6 8.7e-05 22.4 2.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD95616.1 - 0.00014 21.5 7.0 0.00032 20.4 4.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGD95616.1 - 0.00032 20.3 4.2 0.00079 19.0 2.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Lge1 PF11488.3 EGD95616.1 - 0.0036 17.4 1.9 0.009 16.1 1.3 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 zf-C3HC4_3 PF13920.1 EGD95616.1 - 0.0055 16.3 6.3 0.012 15.2 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGD95616.1 - 0.0074 16.1 5.2 0.0094 15.8 2.8 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prefoldin PF02996.12 EGD95616.1 - 0.0084 15.7 1.2 0.015 14.9 0.8 1.5 1 0 0 1 1 1 1 Prefoldin subunit Sec23_helical PF04815.10 EGD95616.1 - 0.011 15.1 1.0 0.11 11.9 0.7 2.4 1 1 0 1 1 1 0 Sec23/Sec24 helical domain Apt1 PF10351.4 EGD95616.1 - 0.013 14.4 2.2 0.017 14.0 1.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-RING_6 PF14835.1 EGD95616.1 - 0.015 15.0 3.0 0.043 13.6 2.1 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4403 PF14356.1 EGD95616.1 - 0.037 12.3 0.3 0.74 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4403) DUF4482 PF14818.1 EGD95616.1 - 0.052 14.1 2.6 0.084 13.5 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) PilJ PF13675.1 EGD95616.1 - 0.053 13.8 1.0 0.088 13.1 0.7 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF87 PF01935.12 EGD95616.1 - 0.097 12.4 1.5 0.14 11.9 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF1664 PF07889.7 EGD95616.1 - 0.11 12.2 2.8 0.19 11.5 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4047 PF13256.1 EGD95616.1 - 0.19 11.6 3.7 0.31 10.9 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) zf-rbx1 PF12678.2 EGD95616.1 - 0.21 11.7 3.4 0.62 10.2 2.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger IncA PF04156.9 EGD95616.1 - 0.27 10.8 3.7 0.42 10.1 2.6 1.3 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EGD95616.1 - 0.29 11.4 6.7 0.48 10.7 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) TSC22 PF01166.13 EGD95616.1 - 0.31 11.0 2.8 0.73 9.8 1.8 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family Nup54 PF13874.1 EGD95616.1 - 0.51 10.0 6.3 0.83 9.3 4.4 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 zf-P11 PF03854.9 EGD95616.1 - 0.88 9.0 4.2 2.4 7.6 2.9 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-MIZ PF02891.15 EGD95616.1 - 1.1 8.8 5.6 2.5 7.6 3.8 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_3 PF13920.1 EGD95617.1 - 9.4e-09 34.8 12.2 1.6e-08 34.0 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Asp PF00026.18 EGD95618.1 - 4.3e-16 59.0 0.3 6.5e-16 58.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Syndecan PF01034.15 EGD95618.1 - 0.018 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Mid2 PF04478.7 EGD95618.1 - 0.035 13.5 0.7 0.13 11.6 0.1 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF1191 PF06697.7 EGD95618.1 - 0.15 10.8 0.0 0.33 9.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 EGD95618.1 - 0.79 9.0 8.4 2.5 7.4 5.8 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ThiF PF00899.16 EGD95621.1 - 3.2e-08 33.4 0.0 6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EGD95621.1 - 0.13 11.8 0.0 1.4 8.5 0.0 2.5 3 0 0 3 3 3 0 MoeZ/MoeB domain Rib_5-P_isom_A PF06026.9 EGD95622.1 - 2e-35 121.6 0.0 1e-33 116.0 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) ketoacyl-synt PF00109.21 EGD95623.1 - 3.3e-05 23.5 0.0 5.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain WD40 PF00400.27 EGD95624.1 - 1.3e-14 53.3 0.0 0.00087 19.0 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1961 PF09224.6 EGD95624.1 - 0.052 12.6 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) ATP_bind_1 PF03029.12 EGD95625.1 - 7.3e-76 254.8 0.0 8.9e-76 254.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EGD95625.1 - 0.00038 19.9 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 EGD95625.1 - 0.00049 20.9 1.3 0.0017 19.1 0.1 2.4 2 1 0 2 2 2 1 AAA domain CbiA PF01656.18 EGD95625.1 - 0.00098 18.5 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EGD95625.1 - 0.0011 17.7 0.0 0.0023 16.7 0.0 1.4 1 0 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 EGD95625.1 - 0.0044 16.9 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EGD95625.1 - 0.01 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.5 EGD95625.1 - 0.023 13.9 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EGD95625.1 - 0.038 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGD95625.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Fer4_NifH PF00142.13 EGD95625.1 - 0.052 12.7 0.2 0.19 10.9 0.1 1.9 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_19 PF13245.1 EGD95625.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EGD95625.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EGD95625.1 - 0.13 11.8 0.1 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGD95625.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 EGD95625.1 - 0.14 11.8 0.0 0.44 10.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNase_P_Rpp14 PF01900.14 EGD95626.1 - 7.6e-37 125.5 0.0 9.5e-37 125.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Citrate_synt PF00285.16 EGD95627.1 - 6.9e-18 64.4 0.0 4.3e-15 55.3 0.0 3.2 2 1 1 3 3 3 2 Citrate synthase CoA_binding PF02629.14 EGD95627.1 - 1.6e-17 63.7 0.1 5.9e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EGD95627.1 - 6.1e-13 48.6 0.1 1.1e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EGD95627.1 - 1.3e-05 24.8 0.0 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 EGD95628.1 - 7.2e-08 32.0 0.0 1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain CFEM PF05730.6 EGD95630.1 - 3.3e-16 58.8 7.9 4.6e-16 58.3 5.5 1.2 1 0 0 1 1 1 1 CFEM domain MGC-24 PF05283.6 EGD95630.1 - 0.28 10.9 14.2 0.36 10.5 9.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Rib_recp_KP_reg PF05104.7 EGD95630.1 - 1.5 9.3 8.2 2.1 8.8 5.7 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region MSA-2c PF12238.3 EGD95630.1 - 2.2 7.8 9.4 3 7.4 6.5 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Amidase PF01425.16 EGD95633.1 - 1.2e-85 288.0 0.0 1.4e-85 287.7 0.0 1.1 1 0 0 1 1 1 1 Amidase ORC6 PF05460.8 EGD95636.1 - 2.4e-49 168.3 0.2 3.1e-49 167.9 0.2 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Senescence_reg PF04520.8 EGD95636.1 - 0.00072 20.0 2.5 0.035 14.6 0.2 2.3 2 0 0 2 2 2 2 Senescence regulator DUF2419 PF10343.4 EGD95637.1 - 2.4e-137 456.9 0.0 2.8e-137 456.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) ThiF PF00899.16 EGD95638.1 - 3.5e-42 143.4 0.0 7.1e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EGD95638.1 - 5.2e-28 96.4 0.9 1.1e-27 95.4 0.6 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGD95638.1 - 3.5e-22 77.5 1.6 3.5e-22 77.5 1.1 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EGD95638.1 - 4.7e-22 77.9 0.4 1.1e-21 76.7 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EGD95638.1 - 0.00031 20.9 0.0 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EGD95638.1 - 0.007 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EGD95638.1 - 0.064 13.6 0.1 3.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FeoA PF04023.9 EGD95638.1 - 0.13 12.2 0.0 0.46 10.4 0.0 2.0 1 0 0 1 1 1 0 FeoA domain Glt_symporter PF03616.9 EGD95638.1 - 0.19 10.2 0.1 0.28 9.6 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter adh_short PF00106.20 EGD95639.1 - 5.9e-24 84.8 2.1 3e-23 82.5 1.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD95639.1 - 6.9e-11 42.3 0.1 1.1e-10 41.6 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD95639.1 - 1.3e-08 34.7 2.4 2.1e-07 30.8 1.7 2.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD95639.1 - 4.6e-05 22.9 0.1 0.00015 21.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGD95639.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EGD95639.1 - 0.0039 16.1 0.0 0.0065 15.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EGD95639.1 - 0.0067 16.5 0.3 0.46 10.5 0.0 2.9 2 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase APH PF01636.18 EGD95640.1 - 9.3e-07 28.8 1.9 1.1e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGD95640.1 - 1.9e-06 27.2 0.0 4.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EGD95640.1 - 0.0012 17.9 0.0 0.0029 16.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGD95640.1 - 0.0016 18.0 0.4 0.0069 15.9 0.0 2.2 3 0 0 3 3 3 1 Choline/ethanolamine kinase HSDR_N_2 PF13588.1 EGD95640.1 - 0.01 15.5 0.1 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) Skp1_POZ PF03931.10 EGD95641.1 - 4.9e-10 39.3 0.0 6.1e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain tRNA_int_end_N2 PF12928.2 EGD95642.1 - 1.2e-32 111.1 0.0 1.8e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EGD95642.1 - 0.005 16.3 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Arrestin_C PF02752.17 EGD95644.1 - 2.1e-15 57.0 0.0 7.7e-15 55.1 0.0 1.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.16 EGD95645.1 - 2.1e-34 118.9 0.0 2.5e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-ZPR1 PF03367.8 EGD95646.1 - 6.3e-100 331.0 0.0 6.1e-49 165.2 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 EGD95646.1 - 0.033 13.8 1.5 1.8 8.2 0.0 2.6 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-ISL3 PF14690.1 EGD95646.1 - 0.039 13.9 7.6 3.1 7.9 0.4 3.4 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 UPF0547 PF10571.4 EGD95646.1 - 0.12 12.0 9.8 3.3 7.4 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Cys_rich_KTR PF14205.1 EGD95646.1 - 0.39 10.2 3.2 0.99 8.9 0.1 2.6 3 0 0 3 3 3 0 Cysteine-rich KTR Elf1 PF05129.8 EGD95646.1 - 0.51 10.0 5.4 4.3 7.0 0.0 2.7 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zinc-ribbons_6 PF07191.7 EGD95646.1 - 0.96 9.2 4.2 2.6 7.9 0.1 2.8 2 1 0 2 2 2 0 zinc-ribbons Rpr2 PF04032.11 EGD95647.1 - 1.4e-09 37.6 2.0 2.9e-09 36.6 1.4 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF737 PF05300.6 EGD95647.1 - 4.3 7.2 8.7 2.1 8.2 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF737) DBR1 PF05011.8 EGD95648.1 - 2.9e-46 156.9 0.0 5.9e-46 155.9 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EGD95648.1 - 1.4e-08 34.4 2.8 2.4e-08 33.6 1.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase API5 PF05918.6 EGD95648.1 - 0.14 10.6 0.9 0.18 10.3 0.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2435 PF10363.4 EGD95649.1 - 1.3e-23 82.7 0.0 7e-23 80.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EGD95649.1 - 3.1e-09 36.1 0.0 7.5e-09 34.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DUF3837 PF12939.2 EGD95649.1 - 0.14 12.1 0.2 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) Polysacc_deac_1 PF01522.16 EGD95650.1 - 2.3e-27 95.0 0.0 4.6e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EGD95650.1 - 2e-06 27.6 41.2 1.3e-05 25.0 9.5 2.6 2 0 0 2 2 2 2 Chitin recognition protein FAD_binding_3 PF01494.14 EGD95652.1 - 8.2e-23 81.0 0.0 1.1e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGD95652.1 - 1.6e-10 40.4 1.6 0.00021 20.3 0.6 3.1 1 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGD95652.1 - 4.5e-06 26.9 0.9 0.0013 19.1 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD95652.1 - 0.00058 19.8 0.6 0.0013 18.7 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGD95652.1 - 0.0023 16.8 0.8 0.0041 16.0 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGD95652.1 - 0.027 14.3 0.2 0.09 12.6 0.2 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EGD95652.1 - 0.042 12.6 0.0 0.076 11.8 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.12 EGD95652.1 - 0.046 12.7 0.1 0.074 12.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 EGD95652.1 - 0.073 12.7 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EGD95652.1 - 0.13 11.7 0.4 0.34 10.3 0.2 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EGD95652.1 - 0.15 10.6 0.2 4.3 5.8 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase FAD_oxidored PF12831.2 EGD95652.1 - 0.17 10.9 0.4 0.3 10.1 0.3 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trypsin_2 PF13365.1 EGD95653.1 - 0.0005 20.0 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.4 EGD95653.1 - 0.14 10.5 0.3 0.24 9.7 0.0 1.4 2 0 0 2 2 2 0 Peptidase S46 Clathrin PF00637.15 EGD95654.1 - 3.8e-20 71.9 3.2 3.1e-17 62.5 0.8 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 EGD95654.1 - 7.3e-18 64.1 0.0 1.7e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 EGD95654.1 - 0.00034 20.2 6.1 0.00071 19.2 4.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGD95654.1 - 0.0017 18.1 6.3 0.0033 17.2 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGD95654.1 - 0.0031 17.4 5.6 0.0059 16.6 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 EGD95654.1 - 0.0092 15.6 0.1 0.044 13.4 0.0 2.2 2 0 0 2 2 1 1 TPR repeat TPR_14 PF13428.1 EGD95654.1 - 0.015 15.8 0.0 2.5 8.9 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-rbx1 PF12678.2 EGD95654.1 - 0.021 14.9 3.6 0.041 13.9 2.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGD95654.1 - 0.046 13.3 5.5 0.087 12.4 3.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.12 EGD95654.1 - 0.052 13.4 0.6 0.5 10.4 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_6 PF14835.1 EGD95654.1 - 0.11 12.2 1.2 0.25 11.1 0.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TPR_12 PF13424.1 EGD95654.1 - 0.14 12.1 5.7 0.96 9.4 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 EGD95654.1 - 0.17 11.5 5.6 0.34 10.6 3.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGD95654.1 - 0.44 10.4 2.3 1.3 8.9 1.6 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_8 PF13181.1 EGD95654.1 - 1.2 9.1 6.1 0.32 10.8 0.1 3.2 5 0 0 5 5 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGD95654.1 - 1.2 8.8 3.5 2.7 7.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short_C2 PF13561.1 EGD95655.1 - 3.6e-29 102.2 0.0 4.1e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD95655.1 - 2.1e-27 96.0 0.1 2.7e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD95655.1 - 4.5e-15 55.7 0.0 6e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 KR domain LktC PF06261.6 EGD95655.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 1 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC LRR_4 PF12799.2 EGD95657.1 - 1.8e-21 75.2 39.3 2e-07 30.4 3.2 9.1 4 2 7 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD95657.1 - 9e-19 66.9 43.4 1.2e-05 24.9 2.1 7.3 6 2 2 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 EGD95657.1 - 1.9e-09 36.2 41.1 0.75 10.0 0.8 14.0 13 2 2 15 15 15 4 Leucine Rich Repeat LRR_9 PF14580.1 EGD95657.1 - 2.5e-07 30.4 11.1 0.016 14.7 0.8 4.2 2 1 2 4 4 4 4 Leucine-rich repeat LRR_7 PF13504.1 EGD95657.1 - 9.5e-05 22.0 42.1 4.4 7.9 0.2 12.5 13 0 0 13 13 13 2 Leucine rich repeat LRR_6 PF13516.1 EGD95657.1 - 0.026 14.5 43.4 0.54 10.5 1.7 10.7 9 3 3 12 12 12 0 Leucine Rich repeat IPK PF03770.11 EGD95658.1 - 5.7e-57 192.5 2.0 6.1e-57 192.4 0.0 2.1 2 1 0 2 2 2 1 Inositol polyphosphate kinase Pam17 PF08566.5 EGD95658.1 - 0.031 13.9 0.1 0.094 12.4 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.11 EGD95660.1 - 4.8e-17 61.7 22.0 4.8e-17 61.7 15.3 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EGD95660.1 - 0.00066 19.0 14.2 0.0021 17.3 0.6 3.5 4 0 0 4 4 4 2 Nodulin-like ERCC4 PF02732.10 EGD95661.1 - 6.6e-15 55.1 0.0 6.6e-15 55.1 0.0 2.3 2 2 0 2 2 2 1 ERCC4 domain SspN PF08177.6 EGD95661.1 - 0.077 12.7 0.7 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 Small acid-soluble spore protein N family Mre11_DNA_bind PF04152.9 EGD95662.1 - 1.3e-57 194.5 0.4 2.4e-57 193.6 0.3 1.5 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EGD95662.1 - 5.8e-24 84.5 1.1 9.4e-24 83.9 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EGD95662.1 - 0.027 13.6 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily HNH_2 PF13391.1 EGD95663.1 - 2.8e-10 39.8 0.0 4.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Apc4_WD40 PF12894.2 EGD95664.1 - 0.045 13.2 0.1 0.1 12.0 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Snf7 PF03357.16 EGD95665.1 - 3.3e-20 72.1 14.9 3.7e-20 72.0 8.5 1.9 1 1 1 2 2 2 1 Snf7 DUF826 PF05696.6 EGD95665.1 - 0.048 13.7 1.0 0.12 12.5 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF826) BMFP PF04380.8 EGD95665.1 - 2 8.5 9.9 0.59 10.3 0.3 4.0 3 1 2 5 5 5 0 Membrane fusogenic activity MerR-DNA-bind PF09278.6 EGD95665.1 - 3.4 8.1 15.3 4.1 7.8 1.0 3.8 4 0 0 4 4 4 0 MerR, DNA binding CS PF04969.11 EGD95666.1 - 0.071 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 CS domain zf-CCCH PF00642.19 EGD95667.1 - 0.00012 21.6 1.2 0.00012 21.6 0.8 2.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_4 PF13894.1 EGD95668.1 - 0.049 13.9 3.2 3.2 8.2 1.0 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger KOW PF00467.24 EGD95669.1 - 2.1e-08 33.5 2.1 2.1e-08 33.5 1.5 1.7 2 0 0 2 2 2 1 KOW motif Synaptobrevin PF00957.16 EGD95670.1 - 6.9e-32 108.9 0.0 9.1e-32 108.5 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EGD95670.1 - 1.6e-25 88.4 0.1 2.3e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2628 PF10947.3 EGD95670.1 - 0.18 11.5 1.7 0.33 10.7 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Ion_trans PF00520.26 EGD95671.1 - 3e-06 26.6 23.9 1.9e-05 23.9 16.5 2.1 1 1 0 1 1 1 1 Ion transport protein Git3_C PF11970.3 EGD95672.1 - 0.066 12.9 0.1 0.43 10.3 0.0 2.3 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term NfeD PF01957.13 EGD95672.1 - 0.3 11.2 3.5 0.35 10.9 0.0 2.5 1 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding CPSase_L_D2 PF02786.12 EGD95673.1 - 4.3e-115 382.3 0.3 5.2e-84 280.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EGD95673.1 - 2e-47 159.9 0.0 4.3e-47 158.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EGD95673.1 - 1.8e-44 151.5 0.0 8.4e-44 149.3 0.0 2.2 3 0 0 3 3 3 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EGD95673.1 - 1.3e-42 144.8 0.0 2.6e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EGD95673.1 - 2.6e-40 137.0 0.0 6.5e-40 135.7 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EGD95673.1 - 8.8e-40 135.2 0.0 1.7e-18 66.7 0.0 3.0 3 0 0 3 3 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EGD95673.1 - 5.5e-36 124.0 0.3 1.5e-21 76.9 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain OTCace PF00185.19 EGD95673.1 - 1.4e-35 122.5 0.1 3.8e-35 121.0 0.1 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 EGD95673.1 - 8.1e-23 80.1 0.0 3.9e-22 77.9 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 EGD95673.1 - 3.5e-22 78.5 0.1 4.6e-10 38.7 0.0 4.2 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EGD95673.1 - 1.8e-16 60.1 0.5 6e-08 32.3 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EGD95673.1 - 7.3e-16 57.9 0.1 5.4e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EGD95673.1 - 1.1e-06 28.5 0.3 0.034 13.9 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 EGD95673.1 - 3.3e-06 26.6 0.0 0.0025 17.2 0.0 2.7 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Peptidase_C26 PF07722.8 EGD95673.1 - 1.5e-05 24.5 0.1 0.00034 20.1 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.14 EGD95673.1 - 0.0056 16.2 0.3 5.3 6.5 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 EGD95673.1 - 0.055 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family TrkA_N PF02254.13 EGD95673.1 - 0.075 13.0 0.1 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain ABC_tran PF00005.22 EGD95674.1 - 9.3e-20 71.3 0.0 8.8e-10 39.0 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGD95674.1 - 3e-07 30.7 1.8 0.0013 18.7 0.1 2.6 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EGD95674.1 - 0.00015 21.5 0.0 0.043 13.7 0.0 2.8 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF3584 PF12128.3 EGD95674.1 - 0.18 9.0 0.1 0.39 7.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_23 PF13476.1 EGD95674.1 - 0.3 11.4 0.8 0.55 10.5 0.6 1.4 1 0 0 1 1 1 0 AAA domain Vps51 PF08700.6 EGD95675.1 - 4.9e-16 58.3 1.9 4.9e-16 58.3 1.3 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 EGD95675.1 - 1.8e-05 24.6 2.0 7.5e-05 22.6 0.1 2.6 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.1 EGD95675.1 - 0.15 11.8 4.3 1.7 8.3 0.0 3.0 3 0 0 3 3 3 0 Exocyst complex component Sec5 Baculo_PEP_C PF04513.7 EGD95675.1 - 0.79 9.5 4.8 0.37 10.6 0.2 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 EGD95675.1 - 1.6 7.6 7.3 1.3 7.9 0.7 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MAS20 PF02064.10 EGD95676.1 - 9.9e-19 67.4 0.3 1.9e-18 66.5 0.2 1.4 1 1 0 1 1 1 1 MAS20 protein import receptor DUF3560 PF12083.3 EGD95676.1 - 0.039 14.0 3.0 0.061 13.3 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Glyco_hydro_72 PF03198.9 EGD95677.1 - 2.7e-119 397.8 0.1 3.6e-119 397.4 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EGD95677.1 - 2.3e-05 23.7 0.0 0.00054 19.2 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ank_2 PF12796.2 EGD95678.1 - 4.6e-98 321.7 0.4 5.5e-22 77.9 0.0 7.8 4 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EGD95678.1 - 4e-71 231.4 10.3 3.1e-09 36.1 0.0 15.6 17 0 0 17 17 17 11 Ankyrin repeat Ank_4 PF13637.1 EGD95678.1 - 1.1e-63 210.4 0.3 1.9e-14 53.7 0.0 11.1 7 3 4 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD95678.1 - 3.2e-59 190.9 2.1 1.4e-06 27.9 0.0 17.2 18 0 0 18 18 18 8 Ankyrin repeat Ank_5 PF13857.1 EGD95678.1 - 2e-50 167.6 7.3 1.4e-10 41.0 0.0 14.6 5 3 11 16 16 16 11 Ankyrin repeats (many copies) HeLo PF14479.1 EGD95678.1 - 7.9e-22 78.0 0.0 2.7e-21 76.2 0.0 1.8 1 1 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.7 EGD95678.1 - 1.7e-06 27.8 0.0 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGD95678.1 - 4.8e-05 23.4 0.0 0.00032 20.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGD95678.1 - 5.7e-05 23.2 0.0 0.00018 21.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGD95678.1 - 0.0028 17.8 0.0 0.0072 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 EGD95678.1 - 0.005 16.5 0.0 0.021 14.5 0.0 2.1 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EGD95678.1 - 0.0098 14.7 0.1 0.041 12.7 0.1 1.9 1 1 0 1 1 1 1 NB-ARC domain Shigella_OspC PF06128.6 EGD95678.1 - 0.021 14.3 0.2 3.8 6.9 0.0 3.3 2 1 0 3 3 3 0 Shigella flexneri OspC protein AAA_17 PF13207.1 EGD95678.1 - 0.03 15.1 0.0 0.12 13.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGD95678.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase ATP_bind_1 PF03029.12 EGD95678.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EGD95678.1 - 0.14 11.5 0.0 0.41 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain RRM_1 PF00076.17 EGD95679.1 - 1.4e-06 27.7 0.0 0.00046 19.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD95679.1 - 1.8e-05 24.5 0.0 0.0033 17.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EGD95679.1 - 2.1e-05 24.8 0.8 2.1e-05 24.8 0.6 2.7 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EGD95679.1 - 0.0023 17.7 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF908 PF06012.7 EGD95685.1 - 0.1 11.8 1.7 0.18 11.0 1.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Amino_oxidase PF01593.19 EGD95686.1 - 3.3e-66 224.2 0.4 1.3e-65 222.2 0.3 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGD95686.1 - 2.1e-08 34.0 0.0 4.6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGD95686.1 - 0.00016 21.8 0.4 0.0009 19.3 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD95686.1 - 0.00068 18.6 0.1 0.026 13.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGD95686.1 - 0.004 17.0 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGD95686.1 - 0.004 16.2 0.0 0.15 11.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EGD95686.1 - 0.004 17.5 0.2 0.17 12.3 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD95686.1 - 0.034 13.9 1.8 5.1 6.8 0.0 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EGD95686.1 - 0.042 12.9 0.0 0.084 11.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EGD95686.1 - 0.063 12.1 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.20 EGD95687.1 - 7.7e-15 55.2 0.1 1e-14 54.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD95687.1 - 1.2e-09 38.3 0.0 1.4e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD95687.1 - 0.00042 20.0 0.0 0.00063 19.4 0.0 1.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGD95687.1 - 0.044 12.9 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Permease PF02405.11 EGD95687.1 - 0.091 12.2 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Permease NmrA PF05368.8 EGD95687.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.11 EGD95688.1 - 9.2e-34 116.6 22.9 9.2e-34 116.6 15.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EGD95691.1 - 3.1e-48 164.2 0.2 3e-47 161.0 0.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD95691.1 - 9.7e-05 22.1 5.4 0.0002 21.1 3.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 EGD95693.1 - 9.5e-48 161.9 0.3 5.2e-26 91.5 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGD95693.1 - 5.4e-33 114.5 37.7 1.2e-25 90.4 11.7 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EGD95693.1 - 5.3e-13 49.5 4.5 0.00085 19.3 0.0 4.3 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EGD95693.1 - 7.6e-09 35.1 5.9 0.0022 17.2 0.1 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGD95693.1 - 6e-07 28.8 0.3 0.004 16.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGD95693.1 - 9.2e-07 29.3 0.4 0.00046 20.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EGD95693.1 - 2.2e-06 27.3 0.1 0.01 15.3 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain DUF258 PF03193.11 EGD95693.1 - 3.1e-06 26.4 0.3 0.0017 17.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGD95693.1 - 7.6e-06 26.0 2.5 0.04 13.8 0.1 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.1 EGD95693.1 - 3.3e-05 23.3 0.2 0.044 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EGD95693.1 - 4.1e-05 23.4 0.1 0.064 13.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EGD95693.1 - 0.00022 21.6 0.4 1 9.8 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EGD95693.1 - 0.00039 20.2 0.1 0.012 15.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA PF00004.24 EGD95693.1 - 0.00042 20.5 0.6 0.084 13.0 0.0 3.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD95693.1 - 0.00042 20.4 1.7 0.44 10.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EGD95693.1 - 0.00071 19.3 0.0 0.061 13.0 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase Zeta_toxin PF06414.7 EGD95693.1 - 0.0012 17.9 0.2 0.83 8.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin T2SE PF00437.15 EGD95693.1 - 0.0032 16.4 0.5 0.069 12.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EGD95693.1 - 0.0032 17.0 0.8 0.25 10.8 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 EGD95693.1 - 0.007 16.2 0.2 0.18 11.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 EGD95693.1 - 0.0071 15.1 1.2 1 8.0 0.0 2.4 2 0 0 2 2 2 1 ArgK protein DUF815 PF05673.8 EGD95693.1 - 0.0076 15.2 0.1 0.73 8.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EGD95693.1 - 0.0085 15.5 0.1 0.65 9.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EGD95693.1 - 0.0099 16.6 1.3 1.1 10.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.10 EGD95693.1 - 0.014 14.0 0.1 0.053 12.1 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein RNA_helicase PF00910.17 EGD95693.1 - 0.015 15.4 0.2 1.9 8.6 0.0 2.9 3 0 0 3 3 2 0 RNA helicase NB-ARC PF00931.17 EGD95693.1 - 0.016 14.0 2.8 0.12 11.2 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain AAA_18 PF13238.1 EGD95693.1 - 0.029 14.6 0.3 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGD95693.1 - 0.036 13.9 0.3 2.6 7.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.20 EGD95693.1 - 0.037 13.5 0.2 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.4 EGD95693.1 - 0.096 11.2 2.5 1.6 7.2 0.1 3.2 3 1 0 3 3 3 0 Predicted ATPase of the ABC class MobB PF03205.9 EGD95693.1 - 0.11 12.1 4.4 5.7 6.6 0.6 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EGD95693.1 - 0.12 12.1 1.0 0.53 10.0 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain NTPase_1 PF03266.10 EGD95693.1 - 0.14 11.8 2.9 7.8 6.1 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 EGD95693.1 - 0.16 11.5 0.7 20 4.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EGD95693.1 - 0.26 10.7 6.9 0.48 9.8 0.6 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 EGD95693.1 - 0.51 9.3 0.0 1 8.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 EGD95693.1 - 0.68 9.6 3.9 1.4 8.6 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 EGD95693.1 - 2.3 7.6 5.7 19 4.6 0.1 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein NACHT PF05729.7 EGD95693.1 - 5.6 6.5 9.4 0.68 9.5 0.5 3.2 3 0 0 3 3 3 0 NACHT domain AMP-binding PF00501.23 EGD95695.1 - 0 1419.1 0.0 7.7e-89 297.9 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 EGD95695.1 - 0 1288.1 0.0 6e-53 179.6 0.0 10.7 10 1 0 10 10 10 10 Condensation domain PP-binding PF00550.20 EGD95695.1 - 8.8e-72 237.3 5.0 3.8e-11 43.1 0.2 7.8 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD95695.1 - 4e-24 85.3 1.0 2.2e-06 28.5 0.1 5.9 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EGD95695.1 - 2e-09 36.4 0.6 0.0021 16.5 0.0 5.0 5 0 0 5 5 5 3 Transferase family HxxPF_rpt PF13745.1 EGD95695.1 - 0.00058 20.1 0.0 2 8.7 0.0 4.3 4 0 0 4 4 4 1 HxxPF-repeated domain Sucrose_synth PF00862.14 EGD95695.1 - 0.67 7.8 0.0 1.1 7.0 0.0 1.2 1 0 0 1 1 1 0 Sucrose synthase GMP_synt_C PF00958.17 EGD95697.1 - 2.8e-38 129.5 0.0 5.3e-38 128.6 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EGD95697.1 - 3.7e-38 130.9 0.0 7.2e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EGD95697.1 - 6.8e-11 41.5 0.1 1.4e-06 27.4 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EGD95697.1 - 1.3e-08 34.5 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 EGD95697.1 - 0.002 17.4 0.0 0.016 14.5 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EGD95697.1 - 0.0032 16.0 0.0 0.0071 14.9 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 EGD95697.1 - 0.0038 16.6 0.0 0.0076 15.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EGD95697.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.14 EGD95697.1 - 0.0089 15.1 0.1 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.14 EGD95697.1 - 0.049 13.4 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 EGD95697.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family BCIP PF13862.1 EGD95698.1 - 1.3e-71 240.0 0.1 1.7e-71 239.7 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein CM_2 PF01817.16 EGD95699.1 - 1.9e-06 27.8 0.2 0.00052 20.0 0.0 2.9 2 1 0 2 2 2 2 Chorismate mutase type II WD40 PF00400.27 EGD95700.1 - 8.1e-35 117.4 9.8 3.3e-10 39.4 0.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EGD95700.1 - 1.1e-06 27.1 8.1 0.043 11.9 0.1 4.8 3 2 0 3 3 3 3 Nucleoporin Nup120/160 APG6 PF04111.7 EGD95700.1 - 0.0073 15.3 0.5 0.011 14.8 0.3 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EGD95700.1 - 0.012 15.4 2.9 0.02 14.7 2.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 EGD95700.1 - 0.019 14.9 0.6 0.04 13.9 0.4 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain BBS2_Mid PF14783.1 EGD95700.1 - 0.023 14.4 0.1 0.59 9.9 0.0 3.3 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 EGD95700.1 - 0.064 12.7 0.2 0.4 10.1 0.0 2.1 1 1 0 2 2 2 0 PQQ-like domain Myosin_tail_1 PF01576.14 EGD95700.1 - 0.11 10.2 4.0 0.15 9.7 2.8 1.1 1 0 0 1 1 1 0 Myosin tail IncA PF04156.9 EGD95700.1 - 0.37 10.3 2.3 2.5 7.6 1.6 2.1 1 1 0 1 1 1 0 IncA protein Sad1_UNC PF07738.8 EGD95701.1 - 1.9e-13 50.3 0.0 9.7e-12 44.8 0.0 2.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal COX6A PF02046.10 EGD95701.1 - 0.28 11.0 2.5 0.75 9.7 1.7 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa Suf PF05843.9 EGD95701.1 - 4.3 6.9 14.0 6 6.5 2.9 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3439 PF11921.3 EGD95701.1 - 5.7 6.7 10.9 0.18 11.5 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Kinesin PF00225.18 EGD95702.1 - 5.3e-89 298.2 4.3 2.1e-88 296.2 0.0 3.2 3 0 0 3 3 3 1 Kinesin motor domain IncA PF04156.9 EGD95702.1 - 0.00084 18.9 5.6 0.00084 18.9 3.9 10.9 5 2 6 11 11 11 3 IncA protein Glycos_transf_1 PF00534.15 EGD95703.1 - 5.4e-30 104.0 0.0 4.3e-28 97.8 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGD95703.1 - 9.9e-12 44.9 0.0 1.1e-10 41.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EGD95703.1 - 1.8e-09 37.9 1.7 3.9e-09 36.8 1.2 1.6 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EGD95703.1 - 1.2e-07 31.9 0.1 0.00018 21.6 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGD95703.1 - 3.8e-05 23.8 0.0 8.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Peptidase_M19 PF01244.16 EGD95704.1 - 2.7e-107 358.4 0.0 3.2e-107 358.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF2498 PF10692.4 EGD95705.1 - 0.07 12.7 0.0 0.23 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) GDPD PF03009.12 EGD95705.1 - 0.13 11.7 0.0 0.42 10.0 0.0 1.8 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family GST_C PF00043.20 EGD95707.1 - 8.9e-16 57.6 0.0 1.9e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGD95707.1 - 2.4e-11 43.7 0.0 4.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD95707.1 - 4.3e-10 39.3 0.0 8.3e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD95707.1 - 7.3e-10 38.8 0.0 1.7e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD95707.1 - 2.6e-09 36.9 0.0 5.8e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGD95707.1 - 0.00035 20.9 0.0 0.0005 20.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aldedh PF00171.17 EGD95708.1 - 6.9e-146 486.2 1.4 1.1e-88 297.6 0.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGD95708.1 - 0.083 12.1 0.0 9.1 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Metallophos PF00149.23 EGD95709.1 - 3.3e-36 124.5 0.1 5.3e-31 107.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase 2OG-FeII_Oxy PF03171.15 EGD95710.1 - 4.9e-10 39.5 0.0 4.1e-09 36.6 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGD95710.1 - 2.3e-09 37.7 0.0 5.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ctr PF04145.10 EGD95711.1 - 1.7e-41 141.6 0.1 2.6e-41 141.0 0.1 1.3 1 0 0 1 1 1 1 Ctr copper transporter family RRM_1 PF00076.17 EGD95712.1 - 1.6e-08 34.0 0.0 4.5e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD95712.1 - 7.3e-07 29.0 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD95712.1 - 1.7e-06 27.8 0.0 3.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CrtC PF07143.6 EGD95713.1 - 4e-17 62.4 0.6 7.2e-13 48.5 0.0 2.1 2 0 0 2 2 2 2 Hydroxyneurosporene synthase (CrtC) zf-C2H2 PF00096.21 EGD95714.1 - 5.3e-11 42.1 13.7 7.9e-06 25.9 1.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD95714.1 - 1.7e-07 31.2 10.4 2.2e-06 27.6 1.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGD95714.1 - 4.7e-06 26.5 16.0 3.9e-05 23.6 0.2 3.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGD95714.1 - 0.0019 18.0 4.9 0.54 10.2 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD95714.1 - 0.0026 17.8 10.0 0.015 15.4 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EGD95714.1 - 0.0069 16.1 4.4 0.035 13.8 0.4 2.4 2 0 0 2 2 2 1 BED zinc finger zf-met PF12874.2 EGD95714.1 - 0.011 15.8 11.7 0.38 11.0 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF1631 PF07793.6 EGD95714.1 - 2.4 6.2 6.7 3.1 5.8 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) zf-C2HC_2 PF13913.1 EGD95714.1 - 5.4 6.8 10.1 0.49 10.1 1.3 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type p450 PF00067.17 EGD95716.1 - 3.3e-62 210.5 0.0 4.1e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DivIC PF04977.10 EGD95717.1 - 0.025 14.0 0.1 0.025 14.0 0.0 2.0 3 0 0 3 3 3 0 Septum formation initiator GATA PF00320.22 EGD95718.1 - 1e-15 56.7 1.1 1.9e-15 55.8 0.8 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EGD95718.1 - 0.15 11.3 0.2 0.33 10.3 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Metallophos PF00149.23 EGD95721.1 - 2.3e-07 30.4 2.6 4.2e-07 29.5 1.8 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD95721.1 - 1e-06 28.6 0.0 2e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_S8 PF00410.14 EGD95722.1 - 4.5e-25 87.9 0.1 6.4e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 DUF1995 PF09353.5 EGD95722.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1995) His_Phos_1 PF00300.17 EGD95723.1 - 2.6e-17 63.3 0.0 3.5e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ubiquitin PF00240.18 EGD95724.1 - 8.6e-06 25.0 0.0 1.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EGD95724.1 - 0.0019 18.3 0.0 0.0051 16.9 0.0 1.8 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain PS_Dcarbxylase PF02666.10 EGD95725.1 - 5.1e-81 270.8 0.0 1e-80 269.7 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase E1-E2_ATPase PF00122.15 EGD95726.1 - 4.8e-65 218.8 2.6 9.4e-65 217.8 1.8 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD95726.1 - 2e-33 115.4 7.6 2e-33 115.4 5.3 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD95726.1 - 6.9e-30 105.0 0.0 5.1e-28 98.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD95726.1 - 9.8e-17 60.1 0.0 2.2e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGD95726.1 - 1.4e-16 60.2 0.0 2.8e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGD95726.1 - 1.2e-11 45.1 0.0 3.1e-11 43.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD95726.1 - 7.5e-05 22.4 0.4 0.0024 17.5 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 EGD95726.1 - 0.008 15.7 0.9 0.017 14.7 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) APC10 PF03256.11 EGD95727.1 - 7.3e-43 146.4 0.0 2.2e-42 144.8 0.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Daxx PF03344.10 EGD95727.1 - 0.045 12.2 27.7 0.015 13.8 12.3 2.1 2 0 0 2 2 2 0 Daxx Family Tim54 PF11711.3 EGD95727.1 - 2.1 6.8 7.5 0.34 9.4 2.2 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Mpp10 PF04006.7 EGD95727.1 - 6.6 4.9 30.5 4.6 5.4 13.4 2.1 2 0 0 2 2 2 0 Mpp10 protein Iso_dh PF00180.15 EGD95728.1 - 4.4e-130 433.6 0.0 5e-130 433.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Methyltransf_23 PF13489.1 EGD95730.1 - 1e-19 70.8 0.0 1.6e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD95730.1 - 1.1e-08 35.6 0.0 9.5e-08 32.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD95730.1 - 4.8e-08 32.7 0.0 3.1e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD95730.1 - 3.8e-07 30.4 0.0 1.5e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD95730.1 - 3.3e-05 24.2 0.0 0.00025 21.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD95730.1 - 9.7e-05 22.6 0.0 0.00027 21.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD95730.1 - 0.0065 15.8 0.1 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGD95730.1 - 0.016 15.2 0.0 0.055 13.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EGD95730.1 - 0.019 14.9 0.0 0.032 14.2 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EGD95730.1 - 0.027 13.9 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 EGD95730.1 - 0.03 13.3 0.0 0.06 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EGD95730.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CDP-OH_P_transf PF01066.16 EGD95731.1 - 9.5e-17 61.1 7.1 1.8e-16 60.3 4.9 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PP2C PF00481.16 EGD95732.1 - 6.8e-33 114.1 0.0 9.1e-27 94.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGD95732.1 - 0.0014 18.1 0.0 0.0051 16.2 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C Serglycin PF04360.7 EGD95734.1 - 0.015 15.0 3.5 0.015 15.0 2.4 2.2 2 0 0 2 2 2 0 Serglycin DUF4559 PF15112.1 EGD95734.1 - 0.085 12.0 1.5 0.16 11.1 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) IncA PF04156.9 EGD95734.1 - 0.087 12.4 2.4 0.27 10.7 1.8 1.6 2 0 0 2 2 2 0 IncA protein MscS_porin PF12795.2 EGD95734.1 - 0.096 11.9 5.4 0.16 11.2 3.8 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain GrpE PF01025.14 EGD95734.1 - 0.6 9.6 3.4 7.5 6.0 1.3 2.7 2 1 1 3 3 3 0 GrpE RRM_1 PF00076.17 EGD95735.1 - 1.9e-40 136.2 0.4 2e-18 65.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD95735.1 - 1.3e-32 111.5 0.1 1.5e-17 63.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EGD95735.1 - 2e-30 104.9 0.5 8e-30 102.9 0.2 2.2 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EGD95735.1 - 1.3e-22 79.4 0.0 4.2e-09 36.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGD95735.1 - 0.029 14.1 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif MFS_1 PF07690.11 EGD95736.1 - 6.2e-37 127.1 42.3 1.8e-35 122.3 28.4 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD95736.1 - 3.3e-12 45.7 14.2 3.3e-12 45.7 9.8 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter DUF843 PF05814.6 EGD95736.1 - 0.0016 18.1 1.1 0.42 10.4 0.1 2.6 2 0 0 2 2 2 2 Baculovirus protein of unknown function (DUF843) DUF2561 PF10812.3 EGD95736.1 - 0.034 13.7 0.0 0.034 13.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) DUF4257 PF14074.1 EGD95736.1 - 0.074 12.7 2.3 0.59 9.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4257) OATP PF03137.15 EGD95736.1 - 1.8 6.5 15.2 0.029 12.4 1.6 2.9 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4231 PF14015.1 EGD95736.1 - 7.2 6.6 8.1 15 5.6 1.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Cyt-b5 PF00173.23 EGD95738.1 - 2.6e-19 68.8 0.3 4.5e-18 64.8 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EGD95738.1 - 7.5e-08 32.7 20.8 1.4e-07 31.9 12.5 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EGD95738.1 - 0.028 14.4 0.6 0.052 13.5 0.4 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region OMPdecase PF00215.19 EGD95740.1 - 1.5e-08 34.3 0.0 4.4e-07 29.5 0.0 2.5 2 1 1 3 3 3 2 Orotidine 5'-phosphate decarboxylase / HUMPS family Cu-oxidase_2 PF07731.9 EGD95741.1 - 2e-45 153.6 9.3 5.8e-41 139.2 0.4 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGD95741.1 - 1e-41 141.3 3.4 1e-38 131.6 0.3 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGD95741.1 - 2.1e-37 128.4 1.1 3.1e-33 114.9 0.2 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EGD95741.1 - 0.00066 19.5 0.0 4.1 7.3 0.0 3.5 2 1 0 2 2 2 2 Cupredoxin-like domain FTR1 PF03239.9 EGD95742.1 - 6.8e-82 274.8 11.9 8.4e-82 274.5 8.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4231 PF14015.1 EGD95742.1 - 0.0087 16.0 0.3 0.0087 16.0 0.2 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF4231) DUF3169 PF11368.3 EGD95742.1 - 0.011 14.9 0.6 0.011 14.9 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF2206 PF09971.4 EGD95742.1 - 0.024 13.4 1.3 0.15 10.8 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) DUF4293 PF14126.1 EGD95742.1 - 4.4 7.2 6.8 0.86 9.5 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Adap_comp_sub PF00928.16 EGD95744.1 - 1.9e-19 69.7 0.0 3.1e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGD95744.1 - 4.5e-08 32.9 0.1 7.2e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 EGD95744.1 - 0.0088 16.1 0.2 0.018 15.1 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.4 EGD95745.1 - 2.6e-11 43.1 0.0 4.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.9 EGD95748.1 - 6.1e-109 363.5 13.1 7.4e-109 363.3 9.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EGD95748.1 - 6e-06 26.4 4.2 6e-06 26.4 2.9 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EGD95748.1 - 8.9e-06 25.7 27.4 5.4e-05 23.2 5.7 3.3 2 1 1 3 3 3 2 EamA-like transporter family Acyl_transf_3 PF01757.17 EGD95748.1 - 0.0048 15.7 8.5 0.0048 15.7 5.9 2.2 1 1 1 2 2 2 1 Acyltransferase family Syja_N PF02383.13 EGD95749.1 - 1.2e-93 313.3 0.0 2.1e-93 312.5 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EGD95749.1 - 3.8e-38 129.4 0.0 6.6e-38 128.6 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase HEAT_EZ PF13513.1 EGD95750.1 - 1.2e-28 98.7 8.9 4.9e-13 49.1 0.0 10.8 8 2 3 11 11 11 2 HEAT-like repeat HEAT PF02985.17 EGD95750.1 - 1.8e-26 89.7 16.6 6.4e-05 22.6 0.0 11.7 14 0 0 14 14 13 4 HEAT repeat HEAT_2 PF13646.1 EGD95750.1 - 1e-24 86.6 3.8 3.5e-09 36.8 0.0 8.8 3 3 6 9 9 9 6 HEAT repeats Cnd1 PF12717.2 EGD95750.1 - 8.8e-10 38.7 0.2 0.0058 16.4 0.0 6.5 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EGD95750.1 - 1.9e-09 37.2 0.3 0.005 16.2 0.1 5.9 3 3 2 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EGD95750.1 - 5.4e-09 36.3 0.0 0.015 15.6 0.0 4.8 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Xpo1 PF08389.7 EGD95750.1 - 6.2e-06 26.1 0.2 0.00037 20.4 0.0 4.0 4 1 0 4 4 3 1 Exportin 1-like protein RIX1 PF08167.7 EGD95750.1 - 1.2e-05 25.0 2.2 0.061 12.9 0.0 5.1 4 1 2 6 6 6 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EGD95750.1 - 3.4e-05 22.7 6.4 1.2 7.8 0.0 5.0 4 2 0 5 5 5 3 RNAPII transcription regulator C-terminal Arm PF00514.18 EGD95750.1 - 8.3e-05 22.2 3.7 1.7 8.5 0.0 6.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EGD95750.1 - 0.00027 19.3 0.0 0.22 9.8 0.0 3.8 2 2 1 3 3 3 1 Adaptin N terminal region IBN_N PF03810.14 EGD95750.1 - 0.0052 16.6 1.4 0.14 12.1 0.0 3.8 3 1 0 3 3 2 1 Importin-beta N-terminal domain Dopey_N PF04118.9 EGD95750.1 - 0.01 14.6 0.3 0.03 13.0 0.0 1.9 2 0 0 2 2 2 0 Dopey, N-terminal Sec7_N PF12783.2 EGD95750.1 - 0.015 14.7 0.8 0.16 11.3 0.1 2.7 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DNA_alkylation PF08713.6 EGD95750.1 - 0.1 12.1 0.0 2.6 7.4 0.0 2.7 3 0 0 3 3 3 0 DNA alkylation repair enzyme HEAT_PBS PF03130.11 EGD95750.1 - 0.16 12.5 4.5 22 5.8 0.0 5.3 7 0 0 7 7 4 0 PBS lyase HEAT-like repeat CDC45 PF02724.9 EGD95750.1 - 0.63 8.0 2.0 0.96 7.4 1.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2846 PF11008.3 EGD95751.1 - 0.022 14.5 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) Fungal_trans_2 PF11951.3 EGD95753.1 - 1.5e-09 36.9 1.1 2.5e-09 36.2 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD95753.1 - 3.2e-07 30.1 15.5 5.9e-07 29.2 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_15 PF13429.1 EGD95753.1 - 0.16 11.0 2.1 0.49 9.4 0.4 2.1 1 1 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C12 PF01088.16 EGD95754.1 - 1.6e-69 233.3 0.0 3.5e-69 232.2 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ThiS-like PF14453.1 EGD95758.1 - 0.02 14.6 0.1 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 ThiS-like ubiquitin HRDC PF00570.18 EGD95758.1 - 0.07 12.8 1.0 0.55 9.9 0.6 2.1 2 0 0 2 2 2 0 HRDC domain MFS_1 PF07690.11 EGD95759.1 - 7.5e-27 93.9 33.4 1.1e-26 93.3 22.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Glycophorin_A PF01102.13 EGD95759.1 - 0.24 11.1 0.6 0.7 9.6 0.4 1.8 1 0 0 1 1 1 0 Glycophorin A Amidohydro_2 PF04909.9 EGD95760.1 - 3e-13 49.9 0.0 3.5e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 EGD95761.1 - 3.2e-27 95.0 0.1 5.5e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD95761.1 - 1.6e-10 40.6 7.7 2.9e-10 39.9 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.3 EGD95761.1 - 2.8 7.6 4.6 0.49 10.0 0.3 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension tRNA-synt_2b PF00587.20 EGD95762.1 - 7.7e-48 162.3 0.0 1.1e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGD95762.1 - 0.0002 21.2 0.0 0.0012 18.7 0.0 2.2 3 0 0 3 3 3 1 Anticodon binding domain ECH PF00378.15 EGD95763.1 - 1.2e-37 129.3 0.0 1.5e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pyr_redox_2 PF07992.9 EGD95764.1 - 2.6e-37 128.6 0.6 3.5e-37 128.2 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EGD95764.1 - 6.5e-30 103.3 0.2 2.7e-29 101.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EGD95764.1 - 7.2e-14 51.9 0.1 7.2e-14 51.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD95764.1 - 0.0003 20.9 0.1 0.0042 17.1 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGD95764.1 - 0.011 15.3 0.1 0.034 13.7 0.1 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 EGD95764.1 - 0.055 12.3 0.0 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EGD95764.1 - 0.17 10.7 2.4 0.56 9.0 0.3 2.7 3 1 1 4 4 4 0 Glucose inhibited division protein A Ank_2 PF12796.2 EGD95765.1 - 6.3e-10 39.2 0.2 5.6e-08 33.0 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD95765.1 - 6.6e-09 36.0 1.2 0.00017 21.9 0.0 3.5 3 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD95765.1 - 4.5e-07 29.9 0.1 0.0011 19.1 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EGD95765.1 - 1.6e-05 24.4 0.1 5.6 6.9 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EGD95765.1 - 0.012 15.7 0.3 10 6.7 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat Pkinase PF00069.20 EGD95767.1 - 1.3e-48 165.4 0.0 3.3e-46 157.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95767.1 - 1.3e-31 109.6 0.0 2.1e-30 105.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD95767.1 - 0.00047 19.2 0.0 0.00073 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGD95767.1 - 0.0042 15.9 0.1 0.0077 15.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EGD95767.1 - 0.051 12.3 0.0 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PINIT PF14324.1 EGD95767.1 - 0.57 10.2 2.3 1 9.4 1.6 1.3 1 0 0 1 1 1 0 PINIT domain Mem_trans PF03547.13 EGD95769.1 - 3.3e-56 190.2 0.4 3.9e-56 189.9 0.2 1.1 1 0 0 1 1 1 1 Membrane transport protein Choline_kinase PF01633.15 EGD95770.1 - 2.9e-60 203.4 0.0 6.1e-60 202.3 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EGD95770.1 - 3.5e-16 58.4 0.0 7.3e-16 57.3 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EGD95770.1 - 5.1e-07 29.6 0.4 5.1e-07 29.6 0.3 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Abhydrolase_2 PF02230.11 EGD95771.1 - 5.3e-24 84.8 0.1 1.7e-17 63.6 0.0 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGD95771.1 - 4.2e-06 26.8 0.5 3e-05 24.0 0.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD95771.1 - 4.6e-06 26.4 0.0 7.4e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGD95771.1 - 0.00045 19.7 0.0 0.00099 18.6 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EGD95771.1 - 0.0073 15.5 0.4 0.018 14.2 0.3 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_31 PF01055.21 EGD95772.1 - 5.9e-183 608.6 0.3 7.6e-183 608.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGD95772.1 - 1.8e-10 40.5 0.1 6e-10 38.8 0.1 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like DUF1470 PF07336.6 EGD95773.1 - 0.0073 16.6 3.0 0.3 11.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1470) Asp PF00026.18 EGD95774.1 - 1.4e-05 24.4 0.8 0.0003 20.1 0.6 2.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease IncA PF04156.9 EGD95774.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 EGD95775.1 - 1.2e-18 66.9 39.6 1e-12 47.4 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD95775.1 - 2.3e-15 56.1 24.6 1.2e-14 53.7 17.1 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_92 PF07971.7 EGD95776.1 - 4.6e-140 467.5 0.6 2.7e-137 458.4 0.4 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 ATP-synt_G PF04718.10 EGD95778.1 - 3.6e-28 98.2 0.0 1.5e-27 96.2 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF3813 PF12758.2 EGD95778.1 - 0.15 12.2 0.4 0.24 11.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) ADH_zinc_N PF00107.21 EGD95779.1 - 1.4e-17 63.4 0.0 2.6e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGD95779.1 - 4.1e-14 53.5 0.0 1e-13 52.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD95779.1 - 4.6e-09 35.9 0.0 3.1e-08 33.3 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_1 PF00561.15 EGD95780.1 - 5.5e-16 58.8 0.0 3.4e-15 56.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGD95780.1 - 1.4e-11 44.6 0.0 2.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD95780.1 - 0.033 13.9 0.0 0.18 11.5 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAP_central PF04928.12 EGD95781.1 - 1.4e-102 341.8 0.0 2e-102 341.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EGD95781.1 - 1.3e-49 167.7 0.0 2.5e-49 166.7 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EGD95781.1 - 6.2e-10 39.2 0.0 1.4e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 EGD95781.1 - 0.096 10.2 0.0 0.17 9.3 0.0 1.3 1 0 0 1 1 1 0 Nrap protein Glyco_transf_20 PF00982.16 EGD95782.1 - 1.6e-169 564.3 0.0 1.9e-169 564.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.1 EGD95782.1 - 0.00025 21.2 0.0 0.00065 19.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EGD95782.1 - 0.00082 18.8 0.1 0.0051 16.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EGD95782.1 - 0.004 16.6 0.4 0.0065 15.9 0.3 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain adh_short PF00106.20 EGD95783.1 - 3.6e-26 92.0 2.7 5.4e-26 91.5 1.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD95783.1 - 4.3e-23 82.3 0.7 6.8e-23 81.6 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD95783.1 - 3e-12 46.5 0.9 4.6e-12 45.9 0.6 1.3 1 0 0 1 1 1 1 KR domain Poxvirus_B22R_C PF13168.1 EGD95783.1 - 0.042 13.1 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Poxvirus B22R protein C-terminal DUF3391 PF11871.3 EGD95783.1 - 0.076 13.2 0.0 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) ACC_epsilon PF13822.1 EGD95783.1 - 0.12 12.7 0.2 0.53 10.6 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Amidase PF01425.16 EGD95784.1 - 9.2e-87 291.7 0.0 1.1e-86 291.4 0.0 1.0 1 0 0 1 1 1 1 Amidase Cation_efflux PF01545.16 EGD95785.1 - 1.2e-28 99.9 5.0 1.6e-28 99.6 3.4 1.1 1 0 0 1 1 1 1 Cation efflux family FlgN PF05130.7 EGD95785.1 - 0.047 13.9 2.2 0.12 12.6 1.6 1.6 1 0 0 1 1 1 0 FlgN protein MnhB PF04039.8 EGD95785.1 - 0.092 12.8 0.2 0.092 12.8 0.1 1.8 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter Sulfotransfer_3 PF13469.1 EGD95786.1 - 0.0003 21.7 0.5 0.00055 20.8 0.3 1.5 1 1 0 1 1 1 1 Sulfotransferase family Methyltransf_25 PF13649.1 EGD95787.1 - 9.2e-13 48.4 0.0 2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD95787.1 - 9.1e-08 32.4 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD95787.1 - 6.7e-07 29.1 0.0 2.7e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD95787.1 - 2.6e-05 23.8 0.0 5.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD95787.1 - 2.6e-05 24.7 0.0 4.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD95787.1 - 0.00019 21.4 0.0 0.0005 20.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD95787.1 - 0.00064 20.1 0.0 0.0039 17.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD95787.1 - 0.00089 18.4 0.0 0.0018 17.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_20 PF12147.3 EGD95787.1 - 0.023 13.5 0.0 0.079 11.8 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase HNF-1B_C PF04812.8 EGD95787.1 - 0.098 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus rve_2 PF13333.1 EGD95788.1 - 0.16 12.0 0.5 0.94 9.5 0.0 2.4 2 1 0 2 2 2 0 Integrase core domain 2_5_RNA_ligase2 PF13563.1 EGD95789.1 - 1.9e-33 115.3 0.1 4.2e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 EGD95789.1 - 3.5e-23 81.7 0.0 7.2e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase central domain DUF504 PF04457.7 EGD95789.1 - 5.5e-13 48.8 0.3 1.5e-12 47.4 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF504) Exo_endo_phos PF03372.18 EGD95789.1 - 1.5e-12 48.0 0.1 3e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PAP_RNA-bind PF04926.10 EGD95789.1 - 1.4e-05 24.6 0.0 2.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EGD95789.1 - 0.0002 21.6 0.0 0.001 19.3 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain LigT_PEase PF02834.11 EGD95789.1 - 0.027 14.4 0.0 0.1 12.5 0.0 2.0 1 0 0 1 1 1 0 LigT like Phosphoesterase RTC4 PF14474.1 EGD95789.1 - 0.19 11.6 0.0 6.5 6.7 0.0 2.5 2 0 0 2 2 2 0 RTC4-like domain He_PIG PF05345.7 EGD95790.1 - 0.0067 16.4 1.0 0.021 14.8 0.1 2.3 2 0 0 2 2 2 1 Putative Ig domain HNH_2 PF13391.1 EGD95793.1 - 3.4e-15 55.5 0.0 6.4e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Gon7 PF08738.5 EGD95794.1 - 1.1e-15 57.5 1.2 2e-15 56.6 0.8 1.3 1 1 0 1 1 1 1 Gon7 family Vps39_1 PF10366.4 EGD95795.1 - 1.7e-29 101.9 0.0 1.1e-28 99.4 0.0 2.5 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EGD95795.1 - 2.4e-23 82.3 0.0 1.9e-22 79.5 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EGD95795.1 - 3.8e-18 65.8 0.0 9.4e-18 64.5 0.0 1.6 1 1 0 1 1 1 1 CNH domain TPR_1 PF00515.23 EGD95795.1 - 0.001 18.5 0.0 23 4.7 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGD95795.1 - 0.052 13.1 0.2 37 4.0 0.0 4.2 4 1 0 4 4 4 0 TPR repeat TPR_19 PF14559.1 EGD95795.1 - 0.12 12.6 0.7 10 6.5 0.2 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat 6PF2K PF01591.13 EGD95796.1 - 4.9e-81 271.0 0.0 6.4e-81 270.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGD95796.1 - 1.4e-34 119.4 0.0 2.5e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EGD95796.1 - 1.1e-08 35.0 0.0 2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain APH PF01636.18 EGD95798.1 - 8.6e-19 68.2 0.0 1.8e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD95798.1 - 0.00029 20.5 0.0 0.0007 19.2 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGD95799.1 - 8e-24 84.1 0.0 1.2e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95799.1 - 5.1e-21 74.8 0.0 9.3e-21 74.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGD95799.1 - 0.0055 16.0 0.0 0.0081 15.5 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGD95799.1 - 0.014 15.1 0.2 5.3 6.7 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EGD95799.1 - 0.049 12.5 0.0 0.12 11.3 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.9 EGD95799.1 - 0.062 12.3 0.0 0.13 11.2 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rotamase PF00639.16 EGD95800.1 - 0.00027 21.6 0.6 0.00037 21.1 0.4 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain AD PF09793.4 EGD95800.1 - 0.042 13.6 1.3 0.071 12.9 0.9 1.4 1 0 0 1 1 1 0 Anticodon-binding domain CAF-1_p150 PF11600.3 EGD95800.1 - 0.057 12.7 11.7 0.071 12.4 8.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF883 PF05957.8 EGD95800.1 - 0.13 12.6 3.9 0.23 11.9 2.7 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.3 EGD95800.1 - 0.21 10.5 5.3 0.26 10.3 3.7 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Atg14 PF10186.4 EGD95800.1 - 0.26 10.2 1.9 0.32 9.8 1.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3391 PF11871.3 EGD95800.1 - 0.34 11.1 3.5 0.47 10.6 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Borrelia_P83 PF05262.6 EGD95800.1 - 1.4 7.1 8.5 1.6 6.8 5.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein YtxH PF12732.2 EGD95800.1 - 2.1 8.7 9.2 2 8.8 5.3 2.0 1 1 0 1 1 1 0 YtxH-like protein DUF4337 PF14235.1 EGD95800.1 - 3.5 7.4 6.2 5.7 6.7 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) 2-oxoacid_dh PF00198.18 EGD95801.1 - 2e-75 253.0 0.0 2.5e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGD95801.1 - 2.2e-17 62.4 0.4 2.2e-17 62.4 0.3 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EGD95801.1 - 1.6e-15 56.4 0.5 4.2e-15 55.1 0.3 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EGD95801.1 - 0.06 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like Sec7 PF01369.15 EGD95802.1 - 5.1e-63 212.1 0.1 1.4e-62 210.7 0.1 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EGD95802.1 - 9.5e-54 181.3 6.2 9.5e-54 181.3 4.3 2.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGD95802.1 - 3.8e-32 109.6 3.8 3.8e-31 106.4 0.1 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Pex14_N PF04695.8 EGD95803.1 - 0.0088 16.0 0.4 0.074 13.0 0.2 2.1 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region NAD_binding_7 PF13241.1 EGD95804.1 - 2.2e-32 111.3 0.2 3.5e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EGD95804.1 - 2.5e-28 97.1 0.0 3.9e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EGD95804.1 - 9.3e-16 56.5 0.1 1.7e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 EGD95804.1 - 0.037 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EGD95804.1 - 0.097 12.4 1.2 0.19 11.5 0.0 2.0 1 1 1 2 2 2 0 ThiF family ELFV_dehydrog PF00208.16 EGD95804.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pribosyltran_N PF13793.1 EGD95805.1 - 1e-44 150.9 0.2 9.1e-42 141.4 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGD95805.1 - 4.5e-34 117.8 0.1 3.7e-29 101.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGD95805.1 - 7.6e-08 32.1 0.3 1.7e-05 24.5 0.0 2.7 3 0 0 3 3 3 2 Phosphoribosyl transferase domain CbiJ PF02571.9 EGD95805.1 - 0.048 12.9 0.0 0.17 11.1 0.0 1.9 3 0 0 3 3 3 0 Precorrin-6x reductase CbiJ/CobK Isochorismatase PF00857.15 EGD95807.1 - 9e-21 74.5 0.0 1.1e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Methyltransf_10 PF05971.7 EGD95808.1 - 5.6e-71 239.1 0.0 7.3e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 EGD95808.1 - 1.6e-06 27.5 0.0 2.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGD95808.1 - 1.9e-05 24.6 0.0 3.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGD95808.1 - 0.0002 20.6 0.0 0.00034 19.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EGD95808.1 - 0.00068 20.1 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD95808.1 - 0.0033 17.8 0.0 0.011 16.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 EGD95808.1 - 0.0043 16.6 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 EGD95808.1 - 0.0059 16.2 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGD95808.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF633 PF04816.7 EGD95808.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF633) Methyltransf_25 PF13649.1 EGD95808.1 - 0.11 12.8 0.0 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Complex1_LYR_1 PF13232.1 EGD95809.1 - 1.3e-07 31.7 2.9 3e-07 30.5 2.0 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGD95809.1 - 7.7e-07 28.8 2.4 1.9e-06 27.5 1.7 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ank_4 PF13637.1 EGD95810.1 - 7.2e-13 48.6 0.7 1.5e-10 41.3 0.3 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGD95810.1 - 4.1e-08 33.4 1.5 0.00026 21.2 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD95810.1 - 7.6e-07 29.1 5.3 1.8e-05 24.7 0.2 3.5 3 2 0 3 3 3 1 Ankyrin repeats (many copies) KilA-N PF04383.8 EGD95810.1 - 0.0031 17.1 0.2 0.0031 17.1 0.1 2.5 2 1 0 2 2 2 1 KilA-N domain Ank_3 PF13606.1 EGD95810.1 - 0.0031 17.6 4.4 0.071 13.3 0.1 4.3 4 1 0 4 4 4 1 Ankyrin repeat Mtr2 PF10429.4 EGD95810.1 - 0.024 14.3 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 AceK PF06315.6 EGD95810.1 - 0.032 12.5 2.9 0.073 11.3 0.0 2.0 2 0 0 2 2 2 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Baculo_PEP_C PF04513.7 EGD95810.1 - 0.12 12.1 1.1 0.81 9.5 0.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 EGD95810.1 - 0.16 10.3 5.7 0.29 9.4 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ank PF00023.25 EGD95810.1 - 0.21 11.4 8.6 0.21 11.4 0.3 4.1 4 1 0 4 4 3 0 Ankyrin repeat Mnd1 PF03962.10 EGD95810.1 - 2.1 7.9 10.7 1.5 8.4 5.2 2.2 2 0 0 2 2 2 0 Mnd1 family Rick_17kDa_Anti PF05433.10 EGD95811.1 - 0.0015 18.1 23.9 0.0035 16.9 16.6 1.7 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EGD95811.1 - 0.26 10.9 21.1 0.8 9.3 14.6 2.0 1 0 0 1 1 1 0 Glycine zipper DUF1275 PF06912.6 EGD95812.1 - 2.3e-37 128.2 12.8 3.8e-37 127.5 8.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Oxidored_q6 PF01058.17 EGD95813.1 - 4.5e-07 29.5 0.0 6.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit TPR_11 PF13414.1 EGD95814.1 - 4.6e-09 35.7 4.6 1.7e-06 27.6 0.0 4.3 3 1 0 4 4 4 1 TPR repeat TPR_1 PF00515.23 EGD95814.1 - 0.00084 18.8 7.1 0.012 15.1 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGD95814.1 - 0.0038 17.1 6.7 1.2 9.1 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGD95814.1 - 0.017 15.3 3.3 0.96 9.8 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGD95814.1 - 0.02 14.7 0.0 0.02 14.7 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGD95814.1 - 0.16 12.6 0.0 0.16 12.6 0.0 5.5 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGD95814.1 - 0.35 10.7 0.0 0.35 10.7 0.0 4.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGD95814.1 - 0.48 10.8 4.4 9.4 6.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGD95814.1 - 0.97 10.1 0.0 0.97 10.1 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat ABC_tran PF00005.22 EGD95815.1 - 1.7e-35 122.2 0.0 1.5e-23 83.5 0.0 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGD95815.1 - 4.2e-12 46.6 0.0 0.00084 19.3 0.0 3.3 3 0 0 3 3 3 3 AAA domain SMC_N PF02463.14 EGD95815.1 - 5.7e-12 45.3 0.0 3.8e-07 29.5 0.0 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGD95815.1 - 1.5e-10 40.4 0.0 0.0007 19.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGD95815.1 - 4.7e-10 40.1 0.9 0.00021 21.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EGD95815.1 - 1.7e-08 33.7 0.1 7.7e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGD95815.1 - 5.4e-08 33.6 0.0 0.0012 19.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EGD95815.1 - 3.2e-07 30.4 0.1 0.0067 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EGD95815.1 - 7.4e-07 29.1 0.0 0.0099 15.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EGD95815.1 - 1.9e-06 28.0 0.0 0.032 14.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EGD95815.1 - 3.6e-06 26.6 0.0 0.13 11.6 0.0 3.1 3 0 0 3 3 3 2 AAA-like domain Miro PF08477.8 EGD95815.1 - 3.8e-06 27.3 0.0 0.014 15.9 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 EGD95815.1 - 3.8e-06 26.8 0.0 0.12 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGD95815.1 - 6.6e-06 26.4 0.2 0.21 11.8 0.0 3.2 3 0 0 3 3 2 2 AAA domain ArgK PF03308.11 EGD95815.1 - 7.3e-06 24.9 0.1 0.055 12.2 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_16 PF13191.1 EGD95815.1 - 8.7e-06 25.8 0.1 0.26 11.2 0.0 3.6 4 0 0 4 4 3 2 AAA ATPase domain NACHT PF05729.7 EGD95815.1 - 1.6e-05 24.5 0.0 0.025 14.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain PduV-EutP PF10662.4 EGD95815.1 - 1.7e-05 24.3 0.0 0.067 12.6 0.0 3.0 3 0 0 3 3 2 2 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EGD95815.1 - 2.3e-05 24.5 0.0 0.086 13.0 0.0 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EGD95815.1 - 3.3e-05 23.8 0.1 0.14 11.9 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 Dynamin_N PF00350.18 EGD95815.1 - 4.4e-05 23.3 0.0 0.0043 16.8 0.0 2.6 2 1 0 2 2 2 1 Dynamin family RNA_helicase PF00910.17 EGD95815.1 - 5.5e-05 23.3 0.0 0.38 10.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_13 PF13166.1 EGD95815.1 - 6.1e-05 21.6 0.3 0.87 7.9 0.0 3.5 3 1 0 3 3 3 2 AAA domain MobB PF03205.9 EGD95815.1 - 0.0001 22.0 0.1 0.59 9.8 0.0 3.2 3 1 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EGD95815.1 - 0.00025 20.9 0.0 1.6 8.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 EGD95815.1 - 0.00034 20.4 0.0 0.35 10.5 0.0 2.8 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 EGD95815.1 - 0.00078 18.9 0.1 1.1 8.6 0.0 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EGD95815.1 - 0.00096 18.7 0.0 2.3 7.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EGD95815.1 - 0.001 18.4 0.0 1.7 7.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.20 EGD95815.1 - 0.0015 18.1 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 EGD95815.1 - 0.0021 17.1 0.7 0.28 10.1 0.0 3.1 3 1 1 4 4 4 1 AAA ATPase domain ATP_bind_1 PF03029.12 EGD95815.1 - 0.0054 16.2 0.0 2.7 7.4 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SbcCD_C PF13558.1 EGD95815.1 - 0.0058 16.5 0.0 0.02 14.8 0.0 1.9 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit MutS_V PF00488.16 EGD95815.1 - 0.0085 15.5 0.1 0.87 8.9 0.0 2.3 2 0 0 2 2 2 1 MutS domain V Septin PF00735.13 EGD95815.1 - 0.012 14.6 0.4 1 8.2 0.0 2.8 3 0 0 3 3 3 0 Septin FtsK_SpoIIIE PF01580.13 EGD95815.1 - 0.012 15.1 1.3 1.5 8.2 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EGD95815.1 - 0.014 14.5 0.0 1.4 8.0 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGD95815.1 - 0.016 14.9 0.0 3.5 7.4 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 EGD95815.1 - 0.018 14.7 0.0 9 6.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EGD95815.1 - 0.018 13.9 0.1 2.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 EGD95815.1 - 0.022 13.6 0.0 0.33 9.7 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.8 EGD95815.1 - 0.032 13.1 0.0 6.3 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) G-alpha PF00503.15 EGD95815.1 - 0.034 12.8 0.0 0.64 8.6 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit IstB_IS21 PF01695.12 EGD95815.1 - 0.059 12.7 0.0 12 5.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein GTP_EFTU PF00009.22 EGD95815.1 - 0.073 12.4 0.1 5 6.5 0.0 2.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF1510 PF07423.6 EGD95816.1 - 0.0072 15.7 0.6 0.009 15.4 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) ABC2_membrane_3 PF12698.2 EGD95816.1 - 0.028 13.4 0.9 0.043 12.8 0.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Rifin_STEVOR PF02009.11 EGD95816.1 - 0.11 12.1 0.6 0.17 11.5 0.4 1.3 1 0 0 1 1 1 0 Rifin/stevor family HrpA_pilin PF09589.5 EGD95816.1 - 0.13 12.6 3.5 0.078 13.4 0.6 1.8 2 0 0 2 2 2 0 HrpA pilus formation protein DUF912 PF06024.7 EGD95816.1 - 0.16 12.0 5.4 1.1 9.3 2.9 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Spore_III_AF PF09581.5 EGD95816.1 - 3.4 7.4 5.2 1.7 8.4 1.7 1.8 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) UCH PF00443.24 EGD95817.1 - 2.7e-77 259.5 0.0 1.1e-76 257.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD95817.1 - 2.2e-18 66.7 0.0 8.1e-10 38.6 0.0 3.4 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EGD95817.1 - 2e-14 53.7 0.0 6.4e-14 52.1 0.0 2.0 1 0 0 1 1 1 1 DUSP domain PX PF00787.19 EGD95818.1 - 2.7e-19 69.0 0.0 1.1e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EGD95818.1 - 9.8e-12 44.6 6.1 1.6e-05 24.2 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like CDC27 PF09507.5 EGD95819.1 - 6.4 5.8 21.0 8.5 5.4 14.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2428 PF10350.4 EGD95820.1 - 1.1e-52 178.5 0.5 2.3e-52 177.5 0.3 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EGD95820.1 - 0.0035 17.2 0.6 4 7.7 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat Tim17 PF02466.14 EGD95821.1 - 6.8e-29 100.5 2.7 8.1e-29 100.2 1.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.20 EGD95823.1 - 3.1e-49 167.4 0.0 5.4e-49 166.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95823.1 - 2.8e-29 101.9 0.0 4.3e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD95823.1 - 0.0011 18.0 0.0 0.0034 16.3 0.0 1.8 1 1 0 1 1 1 1 Kinase-like ILVD_EDD PF00920.16 EGD95826.1 - 7.9e-202 671.2 0.7 9.3e-202 671.0 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family Lipase_3 PF01764.20 EGD95827.1 - 2.8e-19 69.1 0.0 6.5e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) RAI16-like PF10257.4 EGD95828.1 - 4.8e-80 269.1 0.1 7.9e-80 268.4 0.0 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF3597 PF12200.3 EGD95828.1 - 7.3 6.9 17.6 0.033 14.5 1.7 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3597) BTB PF00651.26 EGD95830.1 - 0.0025 17.7 0.0 0.007 16.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain CBFD_NFYB_HMF PF00808.18 EGD95831.1 - 5.2e-14 52.0 0.8 8.2e-14 51.4 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGD95831.1 - 2.2e-06 27.7 0.2 3.8e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.8 EGD95831.1 - 0.083 12.7 30.6 0.12 12.2 21.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EGD95831.1 - 0.53 8.4 55.5 0.66 8.1 38.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C3HC4_3 PF13920.1 EGD95832.1 - 0.004 16.7 9.6 0.007 16.0 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGD95832.1 - 0.49 10.2 5.5 0.85 9.4 3.8 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EGD95832.1 - 3.4 7.4 10.5 5.6 6.7 7.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF1900 PF08954.6 EGD95833.1 - 1.1e-49 167.4 0.0 8.7e-49 164.5 0.0 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EGD95833.1 - 8.2e-33 111.8 0.0 1.6e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EGD95833.1 - 6.7e-24 82.8 0.9 2.7e-06 27.0 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EGD95833.1 - 0.014 13.5 0.2 0.034 12.2 0.1 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Kinesin PF00225.18 EGD95834.1 - 2.2e-107 358.6 1.3 2.2e-107 358.6 0.9 2.2 2 1 0 2 2 2 1 Kinesin motor domain Sugar_tr PF00083.19 EGD95835.1 - 1e-82 278.1 22.9 1.2e-82 277.8 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD95835.1 - 5.5e-14 51.6 34.3 8.5e-14 51.0 17.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Peptidase_S8 PF00082.17 EGD95836.1 - 4e-43 147.5 14.1 6.6e-43 146.8 9.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD95836.1 - 2.3e-13 50.5 0.3 3.8e-13 49.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3553 PF12073.3 EGD95836.1 - 0.052 12.8 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) Nramp PF01566.13 EGD95837.1 - 1.9e-88 296.6 20.5 1.9e-88 296.6 14.2 1.8 3 0 0 3 3 3 1 Natural resistance-associated macrophage protein CAML PF14963.1 EGD95837.1 - 0.63 9.3 2.9 0.33 10.2 0.1 1.9 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Aminotran_4 PF01063.14 EGD95838.1 - 2.4e-23 82.8 0.0 3e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV TPR_11 PF13414.1 EGD95839.1 - 3.1e-52 174.0 29.8 7.2e-14 51.1 0.6 7.6 3 2 5 9 9 9 9 TPR repeat TPR_1 PF00515.23 EGD95839.1 - 1.4e-41 138.4 34.7 4.5e-06 26.0 0.1 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 EGD95839.1 - 1.2e-39 130.9 33.8 5.5e-05 22.7 0.1 11.6 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_16 PF13432.1 EGD95839.1 - 3.3e-27 94.5 25.2 5.3e-07 30.1 0.1 6.8 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGD95839.1 - 2.9e-26 91.2 32.9 3.7e-07 29.9 0.0 7.4 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 EGD95839.1 - 8.9e-19 66.0 18.5 0.026 14.6 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 EGD95839.1 - 1.4e-15 55.7 20.6 0.0099 15.6 0.5 10.0 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGD95839.1 - 8.8e-15 53.3 33.3 0.012 15.3 0.1 11.0 9 2 2 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGD95839.1 - 2.9e-14 52.2 24.0 0.019 15.5 0.8 10.5 3 3 8 11 11 11 4 Tetratricopeptide repeat TPR_9 PF13371.1 EGD95839.1 - 7.7e-14 51.3 17.4 1.2e-05 25.0 0.1 6.6 4 2 4 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGD95839.1 - 1.4e-13 50.9 26.6 2.3e-06 27.8 1.3 7.6 4 2 3 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 EGD95839.1 - 4.4e-11 42.7 22.4 0.0046 17.0 0.8 5.4 3 1 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 EGD95839.1 - 0.001 18.2 14.5 0.91 8.8 0.0 7.6 8 0 0 8 8 8 1 SHNi-TPR TPR_10 PF13374.1 EGD95839.1 - 0.0025 17.6 19.4 0.18 11.8 0.5 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF1510 PF07423.6 EGD95839.1 - 0.0042 16.4 2.6 0.0075 15.6 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TPR_6 PF13174.1 EGD95839.1 - 0.0053 17.1 28.7 4 8.1 0.6 9.6 11 0 0 11 11 9 2 Tetratricopeptide repeat Transglut_prok PF09017.5 EGD95839.1 - 0.037 13.1 1.4 0.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Microbial transglutaminase Sel1 PF08238.7 EGD95839.1 - 0.092 13.4 10.6 0.76 10.4 0.2 4.7 4 0 0 4 4 3 0 Sel1 repeat MAS20 PF02064.10 EGD95839.1 - 0.33 10.8 2.3 34 4.3 0.0 3.4 3 1 0 3 3 3 0 MAS20 protein import receptor TPR_3 PF07720.7 EGD95839.1 - 4.1 7.3 14.9 8.4 6.3 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat FHA PF00498.21 EGD95840.1 - 2.1e-10 40.5 0.2 4.1e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 FHA domain Sec1 PF00995.18 EGD95842.1 - 5.1e-152 507.4 0.0 5.9e-152 507.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PAT1 PF09770.4 EGD95843.1 - 0.00042 18.7 28.2 0.00042 18.7 19.6 2.1 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 HORMA PF02301.13 EGD95844.1 - 6.1e-49 166.3 0.0 7e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 HORMA domain GTP_EFTU PF00009.22 EGD95845.1 - 2.9e-48 163.8 0.0 4.4e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EGD95845.1 - 1.7e-39 134.0 3.1 2.6e-39 133.4 2.2 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EGD95845.1 - 1.3e-19 69.8 0.0 2.3e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.17 EGD95845.1 - 2.6e-05 23.6 0.0 0.00018 20.9 0.0 2.1 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 EGD95845.1 - 0.00016 21.5 0.0 0.00047 20.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.1 EGD95845.1 - 0.00094 18.9 0.0 0.0025 17.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EGD95845.1 - 0.0014 18.7 0.9 0.0023 17.9 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EGD95845.1 - 0.019 14.1 0.0 0.044 12.9 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit p450 PF00067.17 EGD95846.1 - 1.5e-31 109.4 0.0 2.2e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_18 PF12847.2 EGD95847.1 - 0.0041 17.6 0.0 5.5 7.6 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EGD95847.1 - 0.0048 17.3 0.0 0.62 10.5 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD95847.1 - 0.03 13.9 0.0 0.4 10.2 0.0 2.4 1 1 2 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGD95847.1 - 0.046 14.0 0.0 11 6.4 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EGD95847.1 - 0.06 13.0 0.1 0.13 12.0 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGD95847.1 - 0.13 12.7 0.0 1.7 9.2 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain DUF3328 PF11807.3 EGD95848.1 - 7.2e-29 101.0 0.4 9.6e-29 100.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3040 PF11239.3 EGD95848.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) FAD_binding_4 PF01565.18 EGD95850.1 - 1.4e-23 82.8 5.4 2.2e-23 82.2 3.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD95850.1 - 2.6e-08 33.6 0.0 4.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_S64 PF08192.6 EGD95851.1 - 0.00054 18.4 0.5 0.14 10.5 0.1 2.1 2 0 0 2 2 2 2 Peptidase family S64 Trypsin_2 PF13365.1 EGD95851.1 - 0.00067 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S29 PF02907.10 EGD95851.1 - 0.035 13.6 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Tbf5 PF06331.7 EGD95852.1 - 5.2e-15 54.9 0.1 6.5e-15 54.6 0.1 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 ECH PF00378.15 EGD95853.1 - 8.3e-41 139.7 0.0 1.2e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 2OG-FeII_Oxy_2 PF13532.1 EGD95854.1 - 1.8e-24 86.6 0.0 3.2e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 EGD95854.1 - 5.4e-21 75.2 0.0 2e-14 53.8 0.0 2.3 2 0 0 2 2 2 2 Isochorismatase family GST_N_3 PF13417.1 EGD95854.1 - 0.0015 18.7 0.0 0.0057 16.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain 2OG-FeII_Oxy PF03171.15 EGD95854.1 - 0.0047 17.1 0.0 0.0096 16.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_N_2 PF13409.1 EGD95854.1 - 0.0097 15.8 0.0 0.033 14.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD95854.1 - 0.019 15.0 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Glutaredoxin2_C PF04399.8 EGD95854.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain IlvN PF07991.7 EGD95855.1 - 5.4e-46 155.9 0.0 8.2e-46 155.3 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EGD95855.1 - 2e-44 151.0 0.0 3.5e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EGD95855.1 - 0.0065 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGD95855.1 - 0.13 12.6 0.3 0.38 11.2 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AIG2 PF06094.7 EGD95857.1 - 0.029 14.8 0.0 0.15 12.5 0.0 1.9 1 1 0 1 1 1 0 AIG2-like family PALP PF00291.20 EGD95858.1 - 5.7e-72 242.5 0.3 7.2e-72 242.2 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGD95858.1 - 0.00026 20.1 0.0 0.00045 19.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family CRS1_YhbY PF01985.16 EGD95858.1 - 0.061 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain Mitochondr_Som1 PF11093.3 EGD95861.1 - 1.2e-07 31.4 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 TAF8_C PF10406.4 EGD95862.1 - 1.8e-18 66.3 1.1 4.6e-18 65.0 0.7 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EGD95862.1 - 5.2e-06 26.0 0.1 1.2e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated DUF2695 PF10905.3 EGD95862.1 - 0.058 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Tir_receptor_C PF07489.6 EGD95862.1 - 0.081 12.6 12.4 0.17 11.5 8.6 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Dicty_REP PF05086.7 EGD95862.1 - 0.081 10.6 3.1 0.11 10.2 2.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 EGD95862.1 - 0.6 9.8 22.4 1.3 8.7 15.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 EGD95862.1 - 0.82 9.4 17.6 1.6 8.4 12.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Med3 PF11593.3 EGD95862.1 - 1.6 7.8 10.1 3.2 6.9 7.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sporozoite_P67 PF05642.6 EGD95862.1 - 6.7 4.4 9.7 9.9 3.8 6.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UQ_con PF00179.21 EGD95864.1 - 4.9e-35 120.0 0.0 6.3e-35 119.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD95864.1 - 0.046 13.4 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Chitin_synth_1 PF01644.12 EGD95865.1 - 1.2e-68 229.9 0.0 1.8e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGD95865.1 - 6.5e-28 96.2 0.0 1.2e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGD95865.1 - 6.6e-24 84.1 0.0 7.4e-19 67.5 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EGD95865.1 - 1.1e-11 44.7 0.1 1.1e-11 44.7 0.1 2.5 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGD95865.1 - 6.5e-07 29.3 0.0 2.5e-06 27.4 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase like family 2 AMP-binding PF00501.23 EGD95866.1 - 2e-48 164.8 0.0 2.7e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Opy2 PF09463.5 EGD95867.1 - 4.7e-09 36.1 19.8 8.2e-09 35.3 13.8 1.4 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.5 EGD95867.1 - 4.3e-05 22.7 0.1 4.3e-05 22.7 0.1 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EGD95867.1 - 0.037 12.3 5.0 0.09 11.0 0.0 2.2 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Dicty_REP PF05086.7 EGD95867.1 - 0.2 9.3 9.7 0.26 8.9 6.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 EGD95867.1 - 0.46 10.2 10.4 3.8 7.2 6.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Presenilin PF01080.12 EGD95867.1 - 8.6 5.0 7.6 13 4.5 5.3 1.3 1 0 0 1 1 1 0 Presenilin FLO_LFY PF01698.11 EGD95868.1 - 0.21 10.3 3.5 0.23 10.2 2.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PBP1_TM PF14812.1 EGD95868.1 - 6 7.2 11.9 14 6.1 8.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_11 PF08241.7 EGD95870.1 - 0.00015 22.1 0.0 0.00026 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD95870.1 - 0.0038 16.8 0.0 0.01 15.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD95870.1 - 0.0066 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EGD95870.1 - 0.022 14.0 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TehB PF03848.9 EGD95870.1 - 0.036 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_25 PF13649.1 EGD95870.1 - 0.063 13.6 0.0 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain HET PF06985.6 EGD95871.1 - 3.1e-18 66.2 7.2 1.4e-15 57.6 0.9 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ZZ PF00569.12 EGD95871.1 - 1.9e-13 49.7 26.6 2.3e-09 36.6 7.3 2.5 2 0 0 2 2 2 2 Zinc finger, ZZ type F-box PF00646.28 EGD95872.1 - 0.0017 17.9 0.2 0.036 13.7 0.0 2.8 2 0 0 2 2 2 1 F-box domain Phosphoesterase PF04185.9 EGD95874.1 - 1.9e-70 238.0 1.0 2.9e-70 237.3 0.7 1.2 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.10 EGD95875.1 - 6.1e-44 148.5 1.2 5.6e-42 142.2 0.1 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGD95875.1 - 7.3e-34 116.2 9.2 1.3e-33 115.3 1.5 3.1 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EGD95875.1 - 1.4e-14 54.2 0.0 1.9e-12 47.3 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase WW PF00397.21 EGD95876.1 - 1.5e-05 24.7 0.6 3.7e-05 23.4 0.4 1.7 1 0 0 1 1 1 1 WW domain CobD_Cbib PF03186.8 EGD95876.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 CobD/Cbib protein zf-C2H2_4 PF13894.1 EGD95877.1 - 2.7e-10 39.8 17.0 0.0021 18.2 1.8 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD95877.1 - 1.1e-09 38.0 24.1 0.0011 19.1 3.3 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD95877.1 - 2.4e-05 24.3 15.9 0.08 13.2 0.2 3.9 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGD95877.1 - 0.58 10.1 19.7 0.056 13.3 2.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zinc-ribbons_6 PF07191.7 EGD95877.1 - 2.5 7.9 10.1 0.18 11.5 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbons Pkinase PF00069.20 EGD95879.1 - 7e-18 64.7 0.0 2.4e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EGD95879.1 - 9.8e-18 63.3 2.2 8.2e-09 35.0 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 EGD95879.1 - 5.7e-10 38.4 10.6 0.039 14.0 0.1 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 EGD95879.1 - 3.5e-06 27.2 0.1 0.56 10.5 0.0 3.9 1 1 2 3 3 3 3 HEAT repeats DUF2454 PF10521.4 EGD95879.1 - 0.0052 15.8 0.5 0.019 14.0 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2454) Pkinase_Tyr PF07714.12 EGD95879.1 - 0.026 13.5 0.0 0.046 12.7 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase HEAT_EZ PF13513.1 EGD95879.1 - 0.16 12.5 3.7 0.74 10.3 0.2 3.5 4 0 0 4 4 4 0 HEAT-like repeat RabGAP-TBC PF00566.13 EGD95880.1 - 6.6e-42 143.3 0.0 1.5e-40 138.9 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Peptidase_M6 PF05547.6 EGD95881.1 - 5.6e-06 24.6 1.1 0.00068 17.8 0.4 2.2 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 Abhydrolase_4 PF08386.5 EGD95883.1 - 0.065 13.1 0.0 0.097 12.5 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein COesterase PF00135.23 EGD95885.1 - 4.4e-106 355.7 0.0 5.4e-106 355.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD95885.1 - 7.7e-07 28.8 0.0 2.5e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD95885.1 - 0.00018 20.8 0.0 0.00044 19.5 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGD95885.1 - 0.00043 20.2 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD95885.1 - 0.0043 16.8 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGD95885.1 - 0.043 12.6 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme SmpA_OmlA PF04355.8 EGD95885.1 - 0.053 13.1 0.3 5.4 6.6 0.0 2.5 2 0 0 2 2 2 0 SmpA / OmlA family DUF1749 PF08538.5 EGD95885.1 - 0.064 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF2562 PF10814.3 EGD95885.1 - 0.21 11.5 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) Nop14 PF04147.7 EGD95886.1 - 5.1e-277 921.2 22.2 6e-277 920.9 15.4 1.0 1 0 0 1 1 1 1 Nop14-like family HEAT_2 PF13646.1 EGD95887.1 - 0.004 17.3 0.2 0.0084 16.3 0.1 1.5 1 0 0 1 1 1 1 HEAT repeats PPR_3 PF13812.1 EGD95888.1 - 4.6e-11 42.0 0.0 0.18 12.2 0.0 7.2 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGD95888.1 - 3.2e-08 33.3 0.0 0.022 14.7 0.0 5.2 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.15 EGD95888.1 - 0.0009 19.0 1.2 4.7 7.4 0.0 5.5 6 0 0 6 6 6 1 PPR repeat ORC3_N PF07034.6 EGD95889.1 - 6.5e-39 133.8 0.0 1.7e-37 129.1 0.0 2.4 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Sec66 PF09802.4 EGD95890.1 - 3.7e-74 248.2 0.3 4.5e-74 247.9 0.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF1539 PF07560.6 EGD95890.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Duffy_binding PF05424.6 EGD95890.1 - 0.12 12.2 2.9 0.25 11.1 2.0 1.7 1 1 0 1 1 1 0 Duffy binding domain AAA PF00004.24 EGD95891.1 - 2.5e-46 157.1 0.1 1.2e-41 142.0 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EGD95891.1 - 9.2e-07 28.4 0.0 2.8e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 EGD95891.1 - 3.5e-06 27.1 0.0 4.3e-05 23.5 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EGD95891.1 - 1.1e-05 25.4 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.20 EGD95891.1 - 5.9e-05 22.9 0.0 0.00019 21.2 0.0 1.8 1 0 0 1 1 1 1 Bromodomain AAA_22 PF13401.1 EGD95891.1 - 0.00013 22.0 0.1 0.0024 18.0 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGD95891.1 - 0.00025 20.7 0.1 0.032 13.9 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EGD95891.1 - 0.00043 20.0 0.0 0.0015 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EGD95891.1 - 0.00094 18.6 0.0 0.0029 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGD95891.1 - 0.0023 17.8 0.0 0.01 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGD95891.1 - 0.0041 17.2 0.0 0.015 15.5 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_17 PF13207.1 EGD95891.1 - 0.0058 17.4 0.0 0.0058 17.4 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EGD95891.1 - 0.0061 16.4 0.0 0.022 14.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EGD95891.1 - 0.0066 15.2 0.0 0.018 13.8 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus Sigma54_activ_2 PF14532.1 EGD95891.1 - 0.008 16.2 0.0 0.09 12.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.22 EGD95891.1 - 0.024 14.9 0.0 0.082 13.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 EGD95891.1 - 0.038 13.1 0.0 0.081 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EGD95891.1 - 0.058 12.4 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EGD95891.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EGD95891.1 - 0.062 12.9 0.1 0.27 10.8 0.0 2.2 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EGD95891.1 - 0.063 12.7 0.0 3 7.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.6 EGD95891.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EGD95891.1 - 0.16 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 EGD95891.1 - 0.36 10.7 0.0 0.98 9.3 0.0 1.6 2 0 0 2 2 1 0 Torsin Cauli_AT PF03233.8 EGD95892.1 - 0.085 12.5 0.5 0.13 12.0 0.4 1.3 1 1 0 1 1 1 0 Aphid transmission protein CPSF_A PF03178.10 EGD95893.1 - 6.2e-96 321.2 0.0 1.1e-94 317.1 0.0 2.7 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EGD95893.1 - 0.0051 15.0 0.0 0.035 12.2 0.0 2.1 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term MFS_1 PF07690.11 EGD95894.1 - 8.6e-47 159.5 39.9 7.2e-43 146.6 28.2 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD95894.1 - 2.6e-13 49.3 10.4 2.6e-13 49.3 7.2 3.8 3 1 1 4 4 4 3 Sugar (and other) transporter PALP PF00291.20 EGD95895.1 - 9.5e-28 97.3 0.0 1.9e-26 93.0 0.0 2.1 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 EGD95895.1 - 1e-10 41.9 0.0 6.3e-10 39.3 0.0 2.3 2 1 0 2 2 2 1 Rhodanese-like domain Pkinase PF00069.20 EGD95896.1 - 5.6e-37 127.2 0.0 7e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95896.1 - 2.2e-26 92.5 0.0 2.9e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD95896.1 - 8e-05 22.4 0.1 0.018 14.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EGD95896.1 - 0.011 14.7 0.1 0.39 9.6 0.1 2.4 1 1 1 2 2 2 0 Kinase-like AAA_11 PF13086.1 EGD95898.1 - 3.9e-62 209.9 0.3 7.5e-62 208.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EGD95898.1 - 1.4e-57 194.2 0.0 5.4e-57 192.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGD95898.1 - 5e-15 55.0 1.5 3.6e-13 49.0 0.1 3.2 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 EGD95898.1 - 1.1e-12 47.9 0.0 9.2e-11 41.6 0.0 2.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EGD95898.1 - 1.3e-09 37.9 0.1 0.06 12.8 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EGD95898.1 - 5.5e-08 32.8 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EGD95898.1 - 2.1e-07 30.2 0.1 3e-06 26.4 0.1 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EGD95898.1 - 7.5e-06 26.1 0.1 0.00016 21.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.1 EGD95898.1 - 8.6e-06 25.4 0.0 0.0059 16.1 0.0 3.1 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 EGD95898.1 - 1.1e-05 24.5 0.0 0.1 11.4 0.0 2.5 2 0 0 2 2 2 2 PIF1-like helicase AAA_16 PF13191.1 EGD95898.1 - 3.6e-05 23.8 0.2 0.00023 21.2 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.9 EGD95898.1 - 4.7e-05 23.1 0.0 0.0042 16.7 0.0 3.2 2 1 0 2 2 2 1 Helicase T2SE PF00437.15 EGD95898.1 - 9e-05 21.5 0.0 0.0002 20.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD-helicase PF00580.16 EGD95898.1 - 0.00013 21.4 0.3 0.0011 18.2 0.3 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 EGD95898.1 - 0.00033 19.9 0.0 0.095 11.9 0.0 2.8 3 1 0 3 3 2 1 PhoH-like protein DEAD PF00270.24 EGD95898.1 - 0.00051 19.5 0.7 0.0029 17.1 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.9 EGD95898.1 - 0.00058 19.6 0.1 0.0017 18.1 0.0 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain TrwB_AAD_bind PF10412.4 EGD95898.1 - 0.00075 18.2 0.0 0.0016 17.1 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 EGD95898.1 - 0.0033 17.1 0.0 0.015 14.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EGD95898.1 - 0.0037 16.6 0.0 0.0089 15.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein UvrD_C_2 PF13538.1 EGD95898.1 - 0.0063 16.6 0.3 4.9 7.3 0.0 3.2 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA PF00004.24 EGD95898.1 - 0.0096 16.1 0.1 0.052 13.7 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.18 EGD95898.1 - 0.01 15.2 0.2 0.038 13.3 0.1 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain 4HB_MCP_1 PF12729.2 EGD95898.1 - 0.011 15.1 0.1 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_25 PF13481.1 EGD95898.1 - 0.035 13.4 0.0 0.1 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EGD95898.1 - 0.036 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EGD95898.1 - 0.039 13.3 0.0 0.9 8.9 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Herpes_ori_bp PF02399.10 EGD95898.1 - 0.043 11.7 0.0 0.064 11.2 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Zot PF05707.7 EGD95898.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_33 PF13671.1 EGD95898.1 - 0.053 13.3 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain TK PF00265.13 EGD95898.1 - 0.068 12.7 0.0 0.52 9.8 0.0 2.2 2 0 0 2 2 2 0 Thymidine kinase FtsK_SpoIIIE PF01580.13 EGD95898.1 - 0.068 12.6 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 EGD95898.1 - 0.075 12.9 0.0 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGD95898.1 - 0.11 13.2 0.9 0.42 11.4 0.2 2.4 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EGD95898.1 - 0.16 12.1 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase HhH-GPD PF00730.20 EGD95899.1 - 9.3e-20 70.9 0.0 2.6e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGD95899.1 - 9.7e-07 28.1 0.0 4.2e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif UQ_con PF00179.21 EGD95900.1 - 3.3e-39 133.5 0.0 4.1e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD95900.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Methyltransf_23 PF13489.1 EGD95901.1 - 9.2e-23 80.7 0.0 1.6e-22 79.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD95901.1 - 2.6e-09 37.6 0.1 7.2e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD95901.1 - 1.3e-08 34.5 0.0 3.5e-07 29.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD95901.1 - 1.9e-07 31.4 0.0 1e-06 29.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD95901.1 - 9e-07 29.3 0.0 2.2e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD95901.1 - 2.1e-05 24.8 0.0 9.5e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGD95901.1 - 0.00071 18.6 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGD95901.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EGD95901.1 - 0.032 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EGD95901.1 - 0.12 11.4 0.0 0.38 9.8 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EGD95901.1 - 0.16 11.5 0.0 4.9 6.6 0.0 2.2 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PT PF04886.7 EGD95902.1 - 1.7e-06 27.2 189.2 0.0019 17.4 24.9 9.3 3 2 3 6 6 6 4 PT repeat MBOAT_2 PF13813.1 EGD95904.1 - 4.5e-12 45.8 0.8 4.5e-12 45.8 0.6 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF1467 PF07330.7 EGD95904.1 - 0.88 9.3 6.4 2.9 7.7 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1467) p450 PF00067.17 EGD95905.1 - 2.2e-53 181.4 0.0 2.8e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EGD95906.1 - 2.4e-33 115.1 0.0 7.3e-33 113.5 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD95906.1 - 1.1e-08 35.9 0.0 2.8e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TFIID-31kDa PF02291.10 EGD95906.1 - 0.047 13.4 0.0 0.26 11.0 0.0 2.1 3 0 0 3 3 3 0 Transcription initiation factor IID, 31kD subunit Cu_amine_oxid PF01179.15 EGD95907.1 - 8.5e-175 581.4 0.4 1e-174 581.1 0.3 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EGD95907.1 - 4.7e-07 29.8 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EGD95907.1 - 0.00016 21.7 0.1 0.00029 20.8 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Tim17 PF02466.14 EGD95908.1 - 3.4e-23 82.0 0.8 4.7e-23 81.6 0.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family zf-RING_2 PF13639.1 EGD95910.1 - 5.9e-05 22.8 5.4 5.9e-05 22.8 3.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EGD95910.1 - 0.0038 17.3 3.6 0.0093 16.0 2.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGD95910.1 - 0.02 14.7 4.1 0.02 14.7 2.9 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EGD95910.1 - 0.16 12.0 9.7 0.049 13.6 3.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) COesterase PF00135.23 EGD95911.1 - 1.8e-74 251.4 0.7 8.4e-57 193.0 0.4 3.0 2 1 1 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD95911.1 - 1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_3 PF00933.16 EGD95913.1 - 9.3e-39 133.1 0.0 1.6e-38 132.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain LIM PF00412.17 EGD95914.1 - 8.8e-17 60.9 20.0 8.2e-12 45.0 2.5 3.3 3 1 0 3 3 3 2 LIM domain SRC-1 PF08832.5 EGD95914.1 - 6.3 7.6 8.1 0.43 11.3 1.2 2.4 2 0 0 2 2 2 0 Steroid receptor coactivator Peptidase_S10 PF00450.17 EGD95916.1 - 5.1e-75 253.1 0.3 7.1e-75 252.7 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Ribonucleas_3_3 PF14622.1 EGD95918.1 - 1.1e-06 28.5 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EGD95918.1 - 2.9e-05 24.4 0.0 0.00015 22.2 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain NAD_binding_5 PF07994.7 EGD95920.1 - 1.1e-112 376.3 0.3 1.4e-112 376.0 0.2 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EGD95920.1 - 1.9e-45 153.2 1.5 2.3e-45 152.9 0.4 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Amidase PF01425.16 EGD95922.1 - 8e-82 275.4 0.3 6.3e-80 269.1 0.2 2.1 1 1 0 1 1 1 1 Amidase RhoGAP PF00620.22 EGD95923.1 - 1.4e-38 131.8 0.0 2.2e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Med7 PF05983.6 EGD95923.1 - 0.092 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 MED7 protein L-fibroin PF05849.6 EGD95926.1 - 0.086 12.1 0.1 1.4 8.2 0.0 2.3 2 1 0 2 2 2 0 Fibroin light chain (L-fibroin) WD40 PF00400.27 EGD95927.1 - 1.8e-153 493.6 72.5 6.2e-14 51.2 0.1 14.0 14 0 0 14 14 13 13 WD domain, G-beta repeat Nup160 PF11715.3 EGD95927.1 - 4e-21 74.7 36.9 0.003 15.7 0.1 11.2 3 2 7 11 11 11 10 Nucleoporin Nup120/160 Ank_2 PF12796.2 EGD95927.1 - 8.4e-21 74.1 0.0 9.1e-08 32.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) NACHT PF05729.7 EGD95927.1 - 2.3e-19 69.6 0.0 4.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Ank PF00023.25 EGD95927.1 - 1e-12 47.1 0.3 0.00011 21.7 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EGD95927.1 - 8.7e-09 35.6 0.0 0.014 15.8 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD95927.1 - 1.2e-08 34.3 0.0 0.028 14.6 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGD95927.1 - 1.7e-08 34.4 0.0 0.011 16.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Nucleoporin_N PF08801.6 EGD95927.1 - 1.9e-07 30.2 22.6 0.028 13.1 0.6 6.6 2 2 3 6 6 6 3 Nup133 N terminal like HPS3_N PF14761.1 EGD95927.1 - 4.7e-05 22.9 0.0 1.2 8.4 0.0 3.7 4 0 0 4 4 4 1 Hermansky-Pudlak syndrome 3 AAA_16 PF13191.1 EGD95927.1 - 0.00088 19.3 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGD95927.1 - 0.0025 17.5 0.0 0.0063 16.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Cytochrom_D1 PF02239.11 EGD95927.1 - 0.0028 16.0 9.8 0.34 9.1 0.3 4.1 3 2 1 4 4 4 3 Cytochrome D1 heme domain Methyltransf_PK PF05891.7 EGD95928.1 - 2.2e-66 223.3 0.0 2.4e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.7 EGD95928.1 - 0.00015 22.1 0.1 0.00062 20.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD95928.1 - 0.0028 17.9 0.0 0.0096 16.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EGD95928.1 - 0.066 12.3 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_12 PF08242.7 EGD95928.1 - 0.079 13.4 0.0 0.25 11.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain APH PF01636.18 EGD95930.1 - 2.3e-09 37.3 0.0 9.2e-09 35.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGD95933.1 - 3.6e-27 95.1 0.0 4.5e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95933.1 - 1.4e-08 34.1 0.1 1.4e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase zf-Tim10_DDP PF02953.10 EGD95934.1 - 1.8e-16 59.1 4.5 2.4e-16 58.7 3.1 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Connexin PF00029.14 EGD95934.1 - 0.059 13.4 0.6 0.088 12.8 0.3 1.4 1 1 0 1 1 1 0 Connexin Vicilin_N PF04702.7 EGD95934.1 - 0.099 12.2 2.1 0.11 12.0 1.5 1.1 1 0 0 1 1 1 0 Vicilin N terminal region YqzH PF14164.1 EGD95934.1 - 0.14 12.0 1.1 0.37 10.7 0.4 2.0 2 1 0 2 2 2 0 YqzH-like protein ADH_N PF08240.7 EGD95935.1 - 7e-29 99.7 0.8 1.7e-28 98.5 0.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD95935.1 - 1.5e-17 63.3 0.2 2.8e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Amidase PF01425.16 EGD95936.1 - 3.7e-88 296.2 0.0 4.9e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 Amidase PIG-F PF06699.6 EGD95937.1 - 2.2e-52 177.7 7.3 2.7e-52 177.5 5.1 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2453 PF10507.4 EGD95937.1 - 0.058 13.2 0.0 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2453) DUF4470 PF14737.1 EGD95939.1 - 7.5e-23 80.1 0.1 1.8e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EGD95939.1 - 4.5e-11 42.4 10.5 9.2e-11 41.4 7.3 1.6 1 0 0 1 1 1 1 MYND finger GHL12 PF14882.1 EGD95940.1 - 0.083 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 NTP_transf_5 PF14907.1 EGD95940.1 - 0.12 11.6 0.6 12 5.1 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised nucleotidyltransferase LMBR1 PF04791.11 EGD95941.1 - 4.4e-13 48.6 4.0 4.4e-13 48.6 2.8 2.3 1 1 1 2 2 2 1 LMBR1-like membrane protein DUF4013 PF13197.1 EGD95941.1 - 0.0077 15.5 5.7 0.0077 15.5 3.9 4.3 3 2 1 4 4 4 2 Protein of unknown function (DUF4013) DUF2040 PF09745.4 EGD95941.1 - 0.057 13.2 0.4 0.21 11.4 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) ATS PF15445.1 EGD95942.1 - 0.0087 15.2 0.8 0.01 14.9 0.5 1.1 1 0 0 1 1 1 1 acidic terminal segments, variant surface antigen of PfEMP1 Atg14 PF10186.4 EGD95943.1 - 5.8e-91 304.5 0.0 6.9e-91 304.3 0.0 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 BBP1_C PF15272.1 EGD95943.1 - 0.024 14.1 3.8 0.038 13.5 2.6 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal IncA PF04156.9 EGD95943.1 - 0.16 11.5 2.6 0.25 10.8 1.8 1.3 1 0 0 1 1 1 0 IncA protein Prefoldin_2 PF01920.15 EGD95943.1 - 0.24 11.1 2.4 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Mnd1 PF03962.10 EGD95943.1 - 0.38 10.3 5.8 0.6 9.7 4.0 1.2 1 0 0 1 1 1 0 Mnd1 family Pkinase PF00069.20 EGD95945.1 - 2.5e-07 30.1 0.0 6.9e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95945.1 - 6.7e-07 28.6 0.0 1.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EGD95945.1 - 0.001 18.6 0.0 0.0043 16.6 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF2401 PF10287.4 EGD95946.1 - 1.6e-70 237.2 0.0 2.4e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EGD95946.1 - 5.5e-19 68.0 0.2 1.3e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Zip PF02535.17 EGD95947.1 - 2.2e-51 174.7 7.7 3e-51 174.3 5.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Epiglycanin_C PF14654.1 EGD95947.1 - 0.071 13.1 3.3 0.24 11.4 2.3 1.9 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Thiolase_N PF00108.18 EGD95948.1 - 3.3e-97 324.6 0.1 4.4e-97 324.1 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGD95948.1 - 2.7e-44 149.5 1.9 5.4e-44 148.5 0.8 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGD95948.1 - 1.7e-05 24.4 1.5 5.1e-05 22.8 1.0 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EGD95948.1 - 0.13 11.9 1.8 2.5 7.8 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LysM PF01476.15 EGD95949.1 - 1.5e-16 59.9 0.1 3.5e-06 26.7 0.0 4.4 4 0 0 4 4 4 4 LysM domain UPF0203 PF05254.7 EGD95949.1 - 0.0085 15.9 8.1 2.7 7.9 0.2 4.3 3 2 0 3 3 3 2 Uncharacterised protein family (UPF0203) CarbpepA_inh PF02977.10 EGD95949.1 - 0.014 15.0 5.2 14 5.3 0.0 5.0 5 0 0 5 5 5 0 Carboxypeptidase A inhibitor Phage_GPL PF05926.6 EGD95949.1 - 0.077 12.8 0.0 0.66 9.8 0.0 2.0 2 0 0 2 2 2 0 Phage head completion protein (GPL) GTP_EFTU PF00009.22 EGD95950.1 - 2.1e-43 147.9 0.0 3.3e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGD95950.1 - 4.8e-24 84.2 0.0 1.5e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EGD95950.1 - 2e-18 66.0 0.0 6.6e-18 64.3 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGD95950.1 - 1e-09 38.3 0.1 3.1e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGD95950.1 - 4.7e-07 29.5 0.0 1.2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EGD95950.1 - 5.9e-06 26.2 0.1 1.3e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD95950.1 - 0.0008 19.8 0.0 0.0022 18.4 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGD95950.1 - 0.075 12.2 0.1 0.87 8.7 0.1 2.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Chromate_transp PF02417.10 EGD95951.1 - 8.7e-54 181.6 33.8 2.1e-29 102.2 9.5 2.5 3 0 0 3 3 3 2 Chromate transporter adh_short_C2 PF13561.1 EGD95952.1 - 1.7e-22 80.3 0.0 3.3e-22 79.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD95952.1 - 9.9e-22 77.6 6.6 9.9e-22 77.6 4.5 2.0 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 EGD95952.1 - 1.5e-06 27.8 0.2 4.3e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EGD95952.1 - 0.00027 20.6 2.5 0.00062 19.4 1.2 2.2 1 1 1 2 2 2 1 KR domain Saccharop_dh PF03435.13 EGD95952.1 - 0.00046 19.2 0.1 0.00079 18.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EGD95952.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 EGD95952.1 - 0.019 14.9 1.2 0.065 13.2 0.1 2.2 2 1 0 2 2 2 0 NADH(P)-binding F420_oxidored PF03807.12 EGD95952.1 - 0.03 14.7 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EGD95952.1 - 0.031 13.1 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EGD95952.1 - 0.054 12.1 0.1 0.078 11.6 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 EGD95952.1 - 0.13 11.9 0.1 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF59 PF01883.14 EGD95953.1 - 1.1e-08 34.9 0.1 2.4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 Pheromone PF08015.6 EGD95953.1 - 0.68 10.8 2.9 1.9 9.3 0.0 2.7 2 1 0 2 2 2 0 Fungal mating-type pheromone Fungal_trans PF04082.13 EGD95954.1 - 3.2e-10 39.3 0.1 7.5e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD95954.1 - 2.1e-05 24.3 7.9 3.8e-05 23.5 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRF PF01765.14 EGD95956.1 - 5.3e-37 126.8 2.8 2.8e-36 124.4 1.9 1.9 1 1 0 1 1 1 1 Ribosome recycling factor HSP70 PF00012.15 EGD95957.1 - 1.1e-232 773.3 8.3 1.2e-232 773.1 5.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGD95957.1 - 5.7e-16 58.0 0.6 3.8e-15 55.3 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EGD95957.1 - 0.00017 21.2 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EGD95957.1 - 0.017 14.0 0.6 0.21 10.4 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Bromodomain PF00439.20 EGD95958.1 - 4.9e-29 100.0 1.2 2.7e-16 59.2 0.0 3.2 3 0 0 3 3 3 2 Bromodomain QRPTase_C PF01729.14 EGD95958.1 - 0.022 14.2 0.0 0.059 12.8 0.0 1.6 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Trypan_PARP PF05887.6 EGD95958.1 - 1.2 9.0 29.8 0.37 10.6 10.0 2.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CKS PF01111.14 EGD95959.1 - 1.2e-35 121.1 0.7 1.2e-35 121.1 0.5 1.4 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 EGD95959.1 - 0.21 11.6 1.1 0.64 10.1 0.3 2.2 2 0 0 2 2 2 0 APC 15 residue motif Thioredoxin_4 PF13462.1 EGD95960.1 - 4.2e-11 43.1 0.0 2e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EGD95960.1 - 0.27 10.7 4.1 0.73 9.3 0.1 2.5 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF3844 PF12955.2 EGD95962.1 - 1.9e-39 133.9 4.7 3.5e-39 133.0 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) zf-RING_2 PF13639.1 EGD95963.1 - 1.2e-13 50.6 6.6 1.9e-13 50.0 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGD95963.1 - 3e-08 33.1 4.0 5e-08 32.4 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD95963.1 - 4.7e-07 29.8 4.5 1e-06 28.7 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGD95963.1 - 1.8e-06 27.5 3.8 2.9e-06 26.8 2.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGD95963.1 - 6.4e-06 26.1 5.8 1.1e-05 25.3 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD95963.1 - 3.3e-05 23.4 2.6 5.7e-05 22.7 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGD95963.1 - 0.0024 17.6 3.2 0.0066 16.2 2.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGD95963.1 - 0.036 13.6 5.7 0.062 12.9 3.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGD95963.1 - 0.049 13.3 0.4 0.12 12.1 0.1 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGD95963.1 - 0.051 13.4 5.0 0.11 12.4 3.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 EGD95963.1 - 0.082 12.6 5.7 0.16 11.6 3.9 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EGD95963.1 - 0.45 10.4 3.6 1.4 8.8 2.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EGD95963.1 - 0.74 9.9 5.7 1.6 8.8 3.9 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 EGD95963.1 - 2.3 8.0 7.2 0.34 10.6 1.0 2.1 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 Pro_isomerase PF00160.16 EGD95965.1 - 3.7e-50 170.1 0.7 4.2e-50 169.9 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2c PF01411.14 EGD95966.1 - 3e-216 718.9 0.0 4.6e-216 718.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EGD95966.1 - 5.1e-18 64.6 0.6 1.5e-17 63.2 0.4 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EGD95966.1 - 7.6e-09 35.1 0.4 2.4e-08 33.5 0.3 2.0 1 0 0 1 1 1 1 DHHA1 domain DUF3752 PF12572.3 EGD95968.1 - 1.7e-43 148.3 13.6 1.7e-43 148.3 9.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Sigma70_ner PF04546.8 EGD95968.1 - 0.21 11.1 11.9 1.8 8.1 0.8 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Peptidase_S10 PF00450.17 EGD95969.1 - 5.8e-89 299.1 0.0 7.7e-89 298.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGD95969.1 - 0.0047 16.8 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PHO4 PF01384.15 EGD95970.1 - 0.11 11.1 3.2 0.15 10.6 2.2 1.1 1 0 0 1 1 1 0 Phosphate transporter family Peptidase_S8 PF00082.17 EGD95971.1 - 1.4e-43 149.1 0.8 2.6e-43 148.1 0.5 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD95971.1 - 7.1e-13 48.9 0.0 1.2e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 TBPIP_N PF15517.1 EGD95971.1 - 0.039 13.5 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 TBP-interacting protein N-terminus MIP PF00230.15 EGD95973.1 - 6.8e-58 195.8 3.9 8.8e-58 195.4 2.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.11 EGD95974.1 - 1.8e-71 239.8 0.6 4.1e-71 238.7 0.4 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGD95974.1 - 1.6e-67 227.3 0.0 2.4e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain APH PF01636.18 EGD95975.1 - 0.008 15.9 0.0 0.015 15.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGD95976.1 - 1.6e-28 99.5 0.0 4e-28 98.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95976.1 - 7.4e-15 54.7 0.0 1.8e-14 53.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PrgH PF09480.5 EGD95976.1 - 0.0091 14.9 0.2 0.013 14.3 0.1 1.1 1 0 0 1 1 1 1 Type III secretion system protein PrgH-EprH (PrgH) A_deaminase PF00962.17 EGD95977.1 - 1.3e-112 375.9 0.0 1.7e-112 375.5 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF883 PF05957.8 EGD95978.1 - 7.7 6.9 7.8 22 5.5 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Abhydrolase_6 PF12697.2 EGD95979.1 - 1.1e-24 87.6 0.0 1.3e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD95979.1 - 2.2e-10 40.4 0.0 4.2e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD95979.1 - 0.0073 15.8 0.0 0.39 10.2 0.0 2.7 2 1 1 3 3 3 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EGD95979.1 - 0.0077 15.8 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Peptidase_S9 PF00326.16 EGD95979.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2419 PF10343.4 EGD95979.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) F-box-like PF12937.2 EGD95981.1 - 5.8e-05 22.7 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD95981.1 - 0.00019 21.0 0.0 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain DUF3725 PF12523.3 EGD95981.1 - 0.27 11.3 0.0 0.55 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) RNase_P_p30 PF01876.11 EGD95982.1 - 4.8e-52 175.1 0.1 6.7e-52 174.7 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit p30 DUF4363 PF14276.1 EGD95983.1 - 0.011 15.4 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) p450 PF00067.17 EGD95983.1 - 0.048 12.1 0.0 0.12 10.8 0.0 1.9 1 1 0 1 1 1 0 Cytochrome P450 NmrA PF05368.8 EGD95984.1 - 2e-15 56.6 0.0 4.3e-15 55.6 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD95984.1 - 2.9e-08 33.9 0.0 4.7e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding MFS_1 PF07690.11 EGD95985.1 - 9.3e-30 103.5 71.5 7.4e-27 93.9 29.9 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD95985.1 - 6.2e-11 41.5 6.6 6.2e-11 41.5 4.6 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EGD95985.1 - 0.00017 19.9 11.2 0.00029 19.1 7.7 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4235 PF14019.1 EGD95985.1 - 0.17 11.7 2.5 2.2 8.2 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4235) Voltage_CLC PF00654.15 EGD95986.1 - 0.072 12.0 4.5 0.1 11.6 3.1 1.2 1 0 0 1 1 1 0 Voltage gated chloride channel Peptidase_M56 PF05569.6 EGD95986.1 - 0.87 8.4 6.5 0.21 10.5 1.5 1.9 1 1 1 2 2 2 0 BlaR1 peptidase M56 DUF4231 PF14015.1 EGD95986.1 - 3.8 7.5 6.6 2.4 8.1 2.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) AzlD PF05437.7 EGD95986.1 - 5.8 6.9 10.7 0.22 11.4 2.5 2.2 2 1 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) p450 PF00067.17 EGD95987.1 - 1.6e-59 201.7 0.0 2.1e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 EGD95988.1 - 3.1e-29 101.8 0.0 5.2e-29 101.1 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGD95988.1 - 0.0016 18.1 0.0 0.0037 17.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Dimerisation PF08100.6 EGD95988.1 - 0.012 15.4 0.1 0.051 13.4 0.0 2.3 2 0 0 2 2 2 0 Dimerisation domain AMP-binding PF00501.23 EGD95989.1 - 2e-53 181.3 0.0 3.1e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EGD95989.1 - 5.7e-27 95.4 0.0 4.9e-26 92.3 0.0 2.5 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EGD95989.1 - 3e-09 36.9 0.0 7.9e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EGD95989.1 - 4.1e-05 23.5 0.1 8.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD95989.1 - 0.0019 17.9 0.0 0.0047 16.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S51 PF03575.12 EGD95989.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S51 Methyltransf_2 PF00891.13 EGD95990.1 - 3.4e-39 134.4 0.0 4.8e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGD95990.1 - 0.00037 21.0 0.1 0.0012 19.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD95990.1 - 0.03 14.7 0.0 0.061 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGD95990.1 - 0.056 13.0 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EGD95991.1 - 5.9e-59 199.3 0.0 6.8e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95991.1 - 3.4e-20 72.1 0.0 4.7e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD95991.1 - 6.2e-09 35.9 0.1 0.00015 21.5 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD95991.1 - 0.01 15.3 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EGD95991.1 - 0.052 12.6 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD95991.1 - 0.064 12.2 0.0 0.13 11.1 0.0 1.5 2 0 0 2 2 2 0 Kinase-like V-ATPase_H_N PF03224.9 EGD95991.1 - 0.26 10.3 1.1 0.29 10.1 0.0 1.5 2 0 0 2 2 2 0 V-ATPase subunit H Pkinase PF00069.20 EGD95992.1 - 4.5e-16 58.7 0.0 8.4e-16 57.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD95992.1 - 0.00026 20.1 0.0 0.00037 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.1 EGD95994.1 - 0.01 15.7 0.0 0.059 13.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGD95994.1 - 0.022 14.4 0.2 1 9.0 0.0 2.8 2 0 0 2 2 2 0 TPR repeat tRNA-synt_1 PF00133.17 EGD95996.1 - 2.1e-216 719.6 0.2 9.9e-216 717.3 0.1 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGD95996.1 - 1.2e-34 119.2 0.5 1.2e-34 119.2 0.3 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGD95996.1 - 6.3e-18 64.6 0.6 3.1e-08 32.7 0.0 4.9 3 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EGD95996.1 - 1.3e-09 37.5 3.8 2.6e-06 26.8 0.0 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EGD95996.1 - 0.0035 16.5 0.1 0.24 10.4 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain PepSY PF03413.14 EGD95996.1 - 0.34 11.5 3.3 1.4 9.5 0.0 3.2 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain DnaJ PF00226.26 EGD95998.1 - 8.8e-19 67.0 0.6 2.9e-18 65.3 0.4 2.0 1 0 0 1 1 1 1 DnaJ domain Trypan_PARP PF05887.6 EGD95998.1 - 0.0005 19.9 16.1 0.0005 19.9 11.2 2.7 2 1 1 3 3 3 1 Procyclic acidic repetitive protein (PARP) zf-B_box PF00643.19 EGD95998.1 - 0.0081 16.0 2.4 0.017 15.0 1.7 1.5 1 0 0 1 1 1 1 B-box zinc finger zf-RING_5 PF14634.1 EGD95998.1 - 0.57 9.9 3.6 1.1 9.0 2.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Neisseria_TspB PF05616.8 EGD95998.1 - 1.2 7.3 20.2 2.3 6.4 14.0 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF1664 PF07889.7 EGD95998.1 - 2.7 7.7 7.2 3.3 7.5 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3431 PF11913.3 EGD96000.1 - 2.5e-79 265.8 0.0 3.3e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) SurE PF01975.12 EGD96002.1 - 3.3e-35 121.1 0.2 4.5e-35 120.7 0.2 1.1 1 0 0 1 1 1 1 Survival protein SurE zf-rbx1 PF12678.2 EGD96003.1 - 3.9e-12 46.1 0.6 7.1e-12 45.2 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGD96003.1 - 3.1e-09 36.5 7.8 2.9e-08 33.4 5.4 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGD96003.1 - 1.9e-07 30.5 0.2 4.2e-07 29.5 0.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD96003.1 - 2.1e-07 30.4 3.9 2.3e-06 27.1 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD96003.1 - 2e-05 24.5 1.7 2e-05 24.5 1.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD96003.1 - 0.00032 20.3 3.7 0.0023 17.6 2.9 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGD96003.1 - 0.0034 17.1 5.0 0.055 13.3 3.5 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF329 PF03884.9 EGD96003.1 - 0.0075 15.8 0.4 0.022 14.2 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF329) zf-RING_UBOX PF13445.1 EGD96003.1 - 0.23 11.1 5.6 0.92 9.2 3.9 2.1 1 1 0 1 1 1 0 RING-type zinc-finger Nop14 PF04147.7 EGD96003.1 - 0.47 8.3 16.4 0.67 7.8 11.3 1.2 1 0 0 1 1 1 0 Nop14-like family zf-RING_4 PF14570.1 EGD96003.1 - 1.7 8.2 4.5 0.51 9.9 1.0 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Nop25 PF09805.4 EGD96003.1 - 8.8 6.4 19.2 2.7 8.0 0.3 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) NOA36 PF06524.7 EGD96003.1 - 9 5.4 13.1 20 4.3 9.1 1.5 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.11 EGD96004.1 - 4.9e-21 74.8 35.1 3e-11 42.6 5.0 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.3 EGD96004.1 - 5.1e-11 41.7 4.0 2e-08 33.2 0.0 2.6 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 EGD96004.1 - 0.0003 19.3 17.7 0.0025 16.3 3.9 3.2 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EGD96004.1 - 0.0042 16.8 4.6 1.4 8.7 0.0 3.5 4 0 0 4 4 4 2 MFS_1 like family LacY_symp PF01306.14 EGD96004.1 - 0.015 13.8 11.9 0.027 13.0 1.3 3.2 3 0 0 3 3 3 0 LacY proton/sugar symporter BT1 PF03092.11 EGD96004.1 - 0.17 10.5 7.1 1.1 7.9 0.1 3.2 3 0 0 3 3 3 0 BT1 family ATP_transf PF09830.4 EGD96006.1 - 1.1e-21 76.4 0.1 2e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 EGD96006.1 - 0.034 14.6 0.0 0.077 13.5 0.0 1.6 1 0 0 1 1 1 0 HIT domain zf-C2H2_4 PF13894.1 EGD96007.1 - 0.002 18.3 16.3 0.072 13.4 0.0 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD96007.1 - 0.013 15.7 21.3 0.38 11.1 0.0 5.1 5 1 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EGD96007.1 - 0.062 13.2 1.0 2.4 8.1 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger CGGC PF08821.6 EGD96007.1 - 3.1 7.8 5.2 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 CGGC domain RPN7 PF10602.4 EGD96008.1 - 1.7e-53 180.6 0.1 2.8e-53 179.9 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EGD96008.1 - 2.4e-10 40.6 0.1 7.2e-10 39.1 0.1 1.9 1 0 0 1 1 1 1 PCI domain LEDGF PF11467.3 EGD96008.1 - 0.094 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) DSBA PF01323.15 EGD96009.1 - 1.3e-18 67.2 0.0 1.5e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Methyltransf_23 PF13489.1 EGD96009.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EGD96010.1 - 1.9e-18 66.9 0.0 2.5e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD96010.1 - 6.1e-07 29.2 0.0 9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD96010.1 - 1.6e-06 28.0 0.0 2.1e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGD96010.1 - 0.017 15.0 0.2 0.04 13.9 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EGD96010.1 - 0.042 13.6 0.5 0.95 9.2 0.4 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AA_kinase PF00696.23 EGD96010.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Amino acid kinase family LtrA PF06772.6 EGD96011.1 - 1.8e-17 63.2 20.4 1.8e-17 63.2 14.2 2.1 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) NTR2 PF15458.1 EGD96012.1 - 1.9e-75 253.3 23.3 3.3e-75 252.6 16.2 1.4 1 0 0 1 1 1 1 Nineteen complex-related protein 2 Nup54 PF13874.1 EGD96012.1 - 0.41 10.3 8.4 0.091 12.4 1.4 2.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Spc7 PF08317.6 EGD96012.1 - 7.9 5.0 12.8 0.052 12.1 2.2 2.0 2 1 0 2 2 2 0 Spc7 kinetochore protein LSM PF01423.17 EGD96013.1 - 1.2e-20 72.8 0.5 1.4e-20 72.6 0.4 1.0 1 0 0 1 1 1 1 LSM domain Peptidase_M1 PF01433.15 EGD96014.1 - 0.0012 17.9 0.0 4.1 6.3 0.0 3.4 4 0 0 4 4 4 2 Peptidase family M1 CDP-OH_P_transf PF01066.16 EGD96015.1 - 8.4e-17 61.3 6.5 8.4e-17 61.3 4.5 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PALP PF00291.20 EGD96016.1 - 2.7e-26 92.5 0.1 3.3e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 EGD96016.1 - 0.076 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 LytB protein DUF212 PF02681.9 EGD96016.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Divergent PAP2 family DUF4187 PF13821.1 EGD96017.1 - 2.6e-18 65.3 0.8 2.6e-18 65.3 0.5 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EGD96017.1 - 3.3e-10 39.5 2.6 9.9e-09 34.8 1.8 2.6 1 1 0 1 1 1 1 G-patch domain PH_4 PF15404.1 EGD96017.1 - 3.9 6.9 5.7 0.7 9.4 0.8 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3657 PF12394.3 EGD96020.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3657) Herpes_gE PF02480.11 EGD96020.1 - 0.046 11.9 0.0 0.06 11.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CPSase_L_D2 PF02786.12 EGD96021.1 - 1.2e-106 354.7 0.0 1.9e-83 278.9 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EGD96021.1 - 2.9e-42 143.2 0.1 6.4e-42 142.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EGD96021.1 - 1.3e-36 125.0 0.0 6.5e-17 61.6 0.0 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EGD96021.1 - 3.2e-36 124.7 0.0 9.4e-20 71.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGD96021.1 - 2.9e-22 78.8 0.0 1.9e-07 30.1 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EGD96021.1 - 6.3e-18 64.7 0.0 4.9e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGD96021.1 - 1e-14 54.4 0.1 1.4e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EGD96021.1 - 1.7e-09 37.4 0.0 3.2e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EGD96021.1 - 0.00022 21.1 0.0 0.47 10.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 EGD96021.1 - 0.00033 20.2 0.0 0.078 12.5 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EGD96021.1 - 0.001 18.3 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Pkinase PF00069.20 EGD96023.1 - 4.2e-07 29.3 0.0 8.4e-07 28.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96023.1 - 4.5e-07 29.2 0.0 6.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD96023.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGD96023.1 - 0.022 14.1 0.0 0.029 13.6 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EGD96023.1 - 0.045 12.8 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGD96023.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SET PF00856.23 EGD96024.1 - 2.4e-12 47.4 0.8 1.1e-11 45.3 0.1 2.4 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 EGD96024.1 - 3.8e-10 39.4 6.6 3.8e-10 39.4 4.6 2.1 2 0 0 2 2 2 1 MYND finger V-ATPase_G PF03179.10 EGD96024.1 - 1.7 8.9 5.9 0.34 11.2 1.1 1.9 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Ribosomal_S19 PF00203.16 EGD96025.1 - 1.3e-33 114.3 0.3 1.9e-33 113.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.14 EGD96026.1 - 5.8e-28 97.1 8.9 6.9e-28 96.8 6.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 EGD96026.1 - 0.065 11.3 0.6 0.063 11.4 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Sigma70_r1_1 PF03979.9 EGD96026.1 - 0.18 11.7 0.1 0.18 11.7 0.1 1.9 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 SPT2 PF08243.6 EGD96027.1 - 5.5e-09 36.3 11.6 5.5e-09 36.3 8.0 2.2 2 0 0 2 2 2 1 SPT2 chromatin protein Carb_kinase PF01256.12 EGD96028.1 - 3.7e-55 186.8 0.1 4.7e-54 183.2 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate kinase SRA1 PF07304.6 EGD96028.1 - 0.0081 15.9 0.3 1.6 8.4 0.0 2.5 2 0 0 2 2 2 2 Steroid receptor RNA activator (SRA1) zf-C2H2_4 PF13894.1 EGD96029.1 - 0.00013 22.0 38.8 0.41 11.0 0.2 7.2 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD96029.1 - 0.00054 20.1 40.4 0.044 14.1 0.5 6.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type Peptidase_S8 PF00082.17 EGD96030.1 - 5.5e-38 130.7 5.0 8.1e-38 130.1 3.4 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD96030.1 - 6.9e-12 45.7 0.2 1.2e-11 44.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 OEP PF02321.13 EGD96031.1 - 0.00034 20.2 3.1 0.00079 19.0 2.1 1.5 1 0 0 1 1 1 1 Outer membrane efflux protein zf-C2H2 PF00096.21 EGD96031.1 - 0.0012 19.1 25.5 0.14 12.5 0.3 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD96031.1 - 4 7.9 25.2 7.3 7.1 0.4 5.0 4 0 0 4 4 4 0 C2H2-type zinc finger Reo_sigmaC PF04582.7 EGD96032.1 - 0.0027 16.9 9.9 0.28 10.3 2.1 2.7 1 1 0 2 2 2 2 Reovirus sigma C capsid protein DUF4187 PF13821.1 EGD96032.1 - 3.2 7.4 5.7 1 8.9 0.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Methyltransf_16 PF10294.4 EGD96034.1 - 0.012 15.0 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Putative methyltransferase Peptidase_M36 PF02128.10 EGD96035.1 - 2.2e-157 523.7 7.0 2.8e-157 523.4 4.8 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGD96035.1 - 2.1e-13 49.5 0.9 4.7e-13 48.3 0.6 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 EGD96035.1 - 0.021 14.8 0.2 0.058 13.4 0.0 1.8 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M4_C PF02868.10 EGD96035.1 - 0.024 14.3 0.0 0.072 12.8 0.0 1.8 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Cys_Met_Meta_PP PF01053.15 EGD96036.1 - 6.8e-130 432.8 0.0 8.3e-130 432.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGD96036.1 - 7.1e-06 25.2 0.0 1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD96036.1 - 0.00021 20.5 0.1 0.00035 19.8 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGD96036.1 - 0.003 16.6 0.8 0.0092 15.0 0.6 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGD96036.1 - 0.0034 16.1 0.0 0.0073 15.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Crinivirus_P26 PF07416.6 EGD96036.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Crinivirus P26 protein RNA_pol_Rbc25 PF08292.7 EGD96037.1 - 8.7e-36 122.7 0.0 1.2e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EGD96037.1 - 5.5e-16 58.4 0.1 9.2e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.4 EGD96038.1 - 3.9e-12 45.4 11.2 3.9e-12 45.4 7.8 4.5 2 1 1 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EGD96038.1 - 1.1e-06 28.2 5.9 1.7e-06 27.5 4.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 EGD96039.1 - 5.6e-11 41.9 1.6 3.7e-07 29.6 0.0 3.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD96039.1 - 2.9e-08 33.5 0.1 4e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD96039.1 - 3.6e-08 33.1 0.0 0.0056 16.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 EGD96039.1 - 1.1e-06 27.5 29.1 2e-06 26.6 20.2 1.4 1 0 0 1 1 1 1 Daxx Family DUF572 PF04502.8 EGD96039.1 - 1.1 8.4 38.8 0.084 12.0 23.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) APH PF01636.18 EGD96040.1 - 4.7e-10 39.6 0.0 6.1e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD96040.1 - 0.006 16.1 0.1 0.012 15.1 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EGD96040.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 EGD96040.1 - 0.076 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Sds3 PF08598.6 EGD96042.1 - 4.7e-14 52.4 0.6 2e-13 50.3 0.5 3.5 3 1 0 3 3 3 2 Sds3-like Coiled-coil_56 PF09813.4 EGD96044.1 - 0.0025 17.7 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 EGD96045.1 - 2.1e-75 253.2 1.7 3.4e-75 252.5 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) SMN PF06003.7 EGD96045.1 - 0.082 11.9 2.5 0.18 10.8 1.7 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PCI_Csn8 PF10075.4 EGD96046.1 - 2.3e-15 56.6 0.0 3.4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 PCI PF01399.22 EGD96046.1 - 0.079 13.2 0.0 0.21 11.9 0.0 1.9 1 1 0 1 1 1 0 PCI domain SAC3_GANP PF03399.11 EGD96046.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family ATP-synt_E PF05680.7 EGD96047.1 - 1.6e-23 82.4 0.2 1.7e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF3752 PF12572.3 EGD96047.1 - 0.05 13.7 0.6 0.061 13.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Drf_GBD PF06371.8 EGD96047.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain WD40 PF00400.27 EGD96048.1 - 2.9e-17 61.8 7.9 7.5e-05 22.4 0.1 6.0 7 1 0 7 7 7 4 WD domain, G-beta repeat Ribosomal_60s PF00428.14 EGD96049.1 - 0.14 12.5 0.4 0.14 12.5 0.3 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein PMT PF02366.13 EGD96050.1 - 1.4e-82 276.8 16.4 2.1e-82 276.2 11.4 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGD96050.1 - 8.1e-21 74.4 0.7 6.1e-20 71.5 0.2 2.0 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 EGD96050.1 - 7.7 6.3 22.3 0.044 13.6 7.5 2.9 3 1 1 4 4 4 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Pirin PF02678.11 EGD96051.1 - 1.3e-31 108.5 0.1 2.8e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EGD96051.1 - 2.9e-25 88.3 0.0 9.4e-25 86.7 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EGD96051.1 - 8.7e-05 21.9 1.2 0.0015 18.0 0.7 2.4 2 1 0 2 2 2 1 Cupin domain GATase_4 PF13230.1 EGD96051.1 - 0.092 11.4 0.0 0.19 10.3 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferases class-II APH PF01636.18 EGD96052.1 - 1e-16 61.4 0.0 1.8e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD96052.1 - 0.00049 19.2 0.0 0.18 10.8 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGD96052.1 - 0.002 17.7 0.0 0.003 17.1 0.0 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EGD96052.1 - 0.066 12.5 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 EGD96052.1 - 0.097 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase STT3 PF02516.9 EGD96054.1 - 8.6e-134 447.1 40.6 8.5e-129 430.6 26.2 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PRKCSH PF07915.8 EGD96055.1 - 6.6e-19 68.4 0.1 6.6e-19 68.4 0.0 3.3 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein SHD1 PF03983.7 EGD96056.1 - 8.9e-36 121.3 0.1 1.6e-35 120.5 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 EGD96056.1 - 6e-33 111.9 4.9 5.4e-12 44.9 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 EGD96056.1 - 9.5e-30 101.9 7.0 6.5e-12 44.8 0.1 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EGD96056.1 - 3.7e-23 80.7 0.3 2e-08 33.5 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.6 EGD96056.1 - 0.0043 17.0 16.0 0.0043 17.0 11.1 6.5 2 1 3 5 5 5 1 Domain of unknown function (DUF1720) SH3_3 PF08239.6 EGD96056.1 - 0.012 15.7 1.5 0.7 10.1 0.1 3.3 3 0 0 3 3 3 0 Bacterial SH3 domain DUF4576 PF15144.1 EGD96057.1 - 0.41 10.3 1.7 0.67 9.6 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) CDC27 PF09507.5 EGD96057.1 - 3 6.9 25.3 4.3 6.4 17.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HSCB_C PF07743.8 EGD96058.1 - 2e-17 63.3 0.7 4.6e-17 62.2 0.1 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EGD96058.1 - 2.8e-10 39.7 0.0 1.1e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain 3Beta_HSD PF01073.14 EGD96059.1 - 2.5e-07 29.7 0.3 4.3e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGD96059.1 - 9.3e-06 25.2 0.6 5.6e-05 22.6 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGD96059.1 - 0.002 17.1 0.0 0.015 14.2 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGD96059.1 - 0.0025 17.8 0.5 0.057 13.4 0.3 2.7 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EGD96059.1 - 0.16 11.2 0.0 0.74 9.0 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family F-box-like PF12937.2 EGD96060.1 - 0.00014 21.5 0.4 0.00014 21.5 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGD96060.1 - 0.0029 17.2 1.1 0.0091 15.6 0.8 1.8 1 0 0 1 1 1 1 F-box domain ATP-synt_D PF01813.12 EGD96060.1 - 0.0031 17.1 0.2 0.0062 16.1 0.1 1.4 1 0 0 1 1 1 1 ATP synthase subunit D WD40 PF00400.27 EGD96061.1 - 1.4e-45 151.5 24.4 4.7e-10 38.9 0.6 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EGD96061.1 - 1.7e-14 52.8 0.8 2.8e-14 52.0 0.6 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 EGD96061.1 - 0.054 12.5 0.0 2.8 6.9 0.0 2.5 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 EGD96061.1 - 0.14 11.8 0.0 1.9 8.1 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A SpoIIE PF07228.7 EGD96062.1 - 1.3e-11 44.6 0.1 3.8e-10 39.7 0.1 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EGD96062.1 - 5.4e-08 32.4 0.1 1e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EGD96062.1 - 2.1e-06 27.3 0.0 0.0015 18.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C ComA PF02679.10 EGD96063.1 - 4.8e-81 271.3 0.0 5.6e-81 271.1 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) PWWP PF00855.12 EGD96064.1 - 1.5e-16 60.3 5.6 2.7e-15 56.3 3.8 3.1 1 1 0 1 1 1 1 PWWP domain OPT PF03169.10 EGD96065.1 - 2.5e-84 283.8 47.1 2.9e-84 283.6 32.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3632 PF12311.3 EGD96066.1 - 1.2e-22 80.5 0.0 2e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Pkinase PF00069.20 EGD96067.1 - 1.3e-35 122.8 0.0 2e-21 76.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96067.1 - 8.5e-12 44.6 0.0 5.2e-09 35.5 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGD96067.1 - 0.0049 15.8 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGD96067.1 - 0.0052 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family CAP_GLY PF01302.20 EGD96068.1 - 1.4e-16 59.9 0.3 4e-16 58.4 0.2 1.8 1 0 0 1 1 1 1 CAP-Gly domain Spc7 PF08317.6 EGD96068.1 - 0.0013 17.5 18.4 0.13 10.9 5.2 3.1 2 1 1 3 3 3 3 Spc7 kinetochore protein AAA_13 PF13166.1 EGD96068.1 - 0.23 9.8 14.1 1.6 7.0 5.9 2.0 1 1 1 2 2 2 0 AAA domain Sed5p PF11416.3 EGD96068.1 - 0.25 10.8 1.0 0.79 9.2 0.7 1.9 1 0 0 1 1 1 0 Integral membrane protein Sed5p DUF1664 PF07889.7 EGD96068.1 - 0.59 9.9 12.7 4.3 7.1 1.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PVL_ORF50 PF07768.6 EGD96068.1 - 0.73 9.8 4.6 0.19 11.7 0.2 2.2 1 1 1 2 2 2 0 PVL ORF-50-like family IncA PF04156.9 EGD96068.1 - 1.7 8.2 32.1 3.3 7.2 0.3 3.2 2 1 1 3 3 3 0 IncA protein Syntaxin-6_N PF09177.6 EGD96068.1 - 2 8.8 9.6 6.9 7.1 0.0 3.7 2 1 2 4 4 4 0 Syntaxin 6, N-terminal NPV_P10 PF05531.7 EGD96068.1 - 4.7 7.5 13.6 44 4.4 0.0 4.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein 3-HAO PF06052.7 EGD96069.1 - 1.2e-55 187.1 0.0 1.3e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EGD96069.1 - 4.7e-05 22.7 0.1 6.8e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EGD96069.1 - 0.0098 15.3 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EGD96069.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain RTC_insert PF05189.8 EGD96070.1 - 9.4e-33 112.3 0.0 1.7e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 EGD96070.1 - 1.3e-23 82.9 0.0 1.8e-22 79.2 0.0 2.0 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Avl9 PF09794.4 EGD96071.1 - 0.11 10.9 0.1 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Transport protein Avl9 Peptidase_S9 PF00326.16 EGD96072.1 - 5.3e-51 172.8 0.0 8.6e-51 172.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGD96072.1 - 2.6e-09 36.9 0.0 4.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD96072.1 - 7.4e-07 29.2 0.2 3.5e-06 27.0 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EGD96072.1 - 0.00021 19.9 0.0 0.043 12.2 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Sec63 PF02889.11 EGD96073.1 - 1.4e-191 635.4 0.1 9.3e-106 353.5 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EGD96073.1 - 6.1e-52 175.5 1.0 2.4e-30 105.2 0.0 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EGD96073.1 - 8.9e-15 54.9 0.0 2.4e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGD96073.1 - 3e-10 39.8 0.0 1.8e-09 37.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGD96073.1 - 1.5e-05 25.1 0.5 0.0018 18.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 EGD96073.1 - 0.00031 20.0 0.0 0.038 13.2 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_10 PF12846.2 EGD96073.1 - 0.0094 15.4 0.0 3.6 6.9 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EGD96073.1 - 0.016 14.7 0.0 0.079 12.4 0.0 2.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 EGD96073.1 - 0.023 13.5 0.0 1.5 7.6 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_19 PF13245.1 EGD96073.1 - 0.047 13.4 0.0 2.1 8.1 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain MutS_V PF00488.16 EGD96074.1 - 2.6e-84 282.3 0.0 4.2e-84 281.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGD96074.1 - 2.1e-38 132.1 3.2 4e-38 131.2 2.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGD96074.1 - 7.4e-15 54.9 0.0 1.9e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EGD96074.1 - 2.2e-09 37.5 0.0 6.1e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EGD96074.1 - 0.00011 22.3 0.1 0.0003 20.9 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EGD96074.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EGD96074.1 - 0.017 15.2 0.7 0.25 11.5 0.0 3.0 4 0 0 4 4 4 0 AAA domain AAA_14 PF13173.1 EGD96074.1 - 0.033 14.1 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGD96074.1 - 0.11 12.8 1.1 0.41 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain Ureidogly_hydro PF04115.7 EGD96075.1 - 6.5e-50 168.6 0.0 7.8e-50 168.4 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Catalase PF00199.14 EGD96076.1 - 7.9e-186 617.3 0.1 9.5e-186 617.0 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGD96076.1 - 6.4e-14 51.5 0.2 1.6e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Rer1 PF03248.8 EGD96077.1 - 2.8e-74 248.4 2.9 3.2e-74 248.3 2.0 1.0 1 0 0 1 1 1 1 Rer1 family ECH PF00378.15 EGD96078.1 - 1.2e-72 243.9 0.2 1.5e-72 243.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EGD96078.1 - 0.016 15.3 0.1 0.035 14.2 0.0 1.7 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region adh_short PF00106.20 EGD96080.1 - 2.5e-21 76.3 0.4 3.7e-21 75.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD96080.1 - 5.2e-10 39.2 0.2 6.8e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD96080.1 - 1.2e-09 38.2 0.4 1.6e-09 37.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGD96080.1 - 0.00033 20.1 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD96080.1 - 0.023 13.4 0.1 0.036 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BTB PF00651.26 EGD96081.1 - 6.3e-16 58.3 0.1 2.7e-15 56.3 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain A_deaminase PF00962.17 EGD96082.1 - 7.1e-44 150.0 0.0 2.4e-43 148.3 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Acetyltransf_10 PF13673.1 EGD96083.1 - 1.5e-10 41.2 0.1 9.3e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGD96083.1 - 4.7e-09 36.2 0.0 5.3e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD96083.1 - 8.2e-09 35.3 0.4 1.6e-08 34.4 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EGD96083.1 - 2.6e-05 24.0 0.0 0.00041 20.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD96083.1 - 0.025 14.3 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 EGD96083.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3419 PF11899.3 EGD96084.1 - 1.5e-151 504.4 0.0 2.6e-151 503.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_31 PF13847.1 EGD96084.1 - 1.7e-12 47.1 0.0 5.2e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD96084.1 - 3.5e-12 46.3 0.0 1.3e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD96084.1 - 4e-11 43.2 0.0 1.7e-10 41.2 0.0 2.2 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD96084.1 - 2.9e-10 40.7 0.0 1.4e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD96084.1 - 2.3e-09 37.6 0.0 7.7e-09 35.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD96084.1 - 7.2e-09 35.6 0.0 8.3e-08 32.2 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD96084.1 - 1.5e-08 34.0 0.0 2.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EGD96084.1 - 0.0004 19.9 0.0 0.00076 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EGD96084.1 - 0.0018 17.9 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGD96084.1 - 0.0023 16.9 0.0 0.15 11.1 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_28 PF02636.12 EGD96084.1 - 0.034 13.5 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF3355 PF11835.3 EGD96084.1 - 0.13 12.0 2.5 0.24 11.1 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) Pyr_redox_2 PF07992.9 EGD96084.1 - 0.16 11.8 0.0 0.6 9.9 0.0 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PAS_3 PF08447.6 EGD96085.1 - 7.8e-12 45.1 0.0 2.7e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EGD96085.1 - 3.1e-08 33.9 0.0 1.6e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 EGD96085.1 - 3.3e-06 27.0 0.0 7.5e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EGD96085.1 - 5.3e-06 26.1 0.0 0.00014 21.6 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EGD96085.1 - 0.00034 20.6 0.0 0.0016 18.4 0.0 2.1 2 0 0 2 2 2 1 PAS fold Lipase_3 PF01764.20 EGD96086.1 - 5e-06 26.1 0.0 9.4e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGD96086.1 - 0.0063 16.2 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EGD96086.1 - 0.04 13.6 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) VPS9 PF02204.13 EGD96087.1 - 3.6e-26 91.2 0.0 5.9e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Sel1 PF08238.7 EGD96088.1 - 1.9e-18 66.4 9.3 2e-07 31.3 0.4 3.6 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.1 EGD96088.1 - 0.0045 17.3 2.3 0.22 12.0 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD96088.1 - 0.63 10.7 3.4 0.99 10.1 0.3 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 EGD96089.1 - 1.4e-22 80.0 0.0 1.8e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96089.1 - 3.8e-09 36.0 0.0 0.0013 17.8 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Mt_ATP-synt_B PF05405.9 EGD96090.1 - 3.3e-50 169.7 9.6 4e-50 169.4 6.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 EGD96090.1 - 0.06 13.2 0.4 0.089 12.6 0.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) PBP_sp32 PF07222.7 EGD96090.1 - 0.21 10.7 6.2 0.31 10.1 4.3 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CBF PF03914.12 EGD96091.1 - 3.3e-46 156.7 0.2 7.3e-46 155.6 0.1 1.6 1 0 0 1 1 1 1 CBF/Mak21 family DUF2115 PF09888.4 EGD96091.1 - 0.036 14.1 0.0 0.13 12.3 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF727 PF05303.7 EGD96091.1 - 0.6 9.9 2.7 5.1 6.9 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF727) DUF964 PF06133.6 EGD96092.1 - 0.0013 18.7 4.3 0.091 12.7 0.7 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF964) GPI-anchored PF10342.4 EGD96093.1 - 2.4e-15 56.7 0.0 2.4e-15 56.7 0.0 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Herpes_BLLF1 PF05109.8 EGD96093.1 - 7.3 4.4 31.5 8.8 4.1 21.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF3632 PF12311.3 EGD96095.1 - 1.9e-43 148.4 1.1 2.5e-43 148.0 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Filament PF00038.16 EGD96096.1 - 0.69 9.3 31.9 2 7.8 12.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein ATG16 PF08614.6 EGD96096.1 - 0.85 9.4 35.2 0.48 10.2 11.8 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EGD96096.1 - 8.3 5.9 41.0 0.14 11.6 7.5 2.2 1 1 1 2 2 2 0 IncA protein MMS19_C PF12460.3 EGD96098.1 - 7.9e-124 413.5 16.1 7.9e-124 413.5 11.1 3.2 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EGD96098.1 - 1.2e-93 313.2 0.3 3.5e-92 308.3 0.0 3.2 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 EGD96098.1 - 2e-07 31.1 10.2 1 9.7 0.1 6.2 5 1 0 5 5 5 4 HEAT repeats HEAT PF02985.17 EGD96098.1 - 0.052 13.6 12.1 23 5.4 0.2 6.4 6 0 0 6 6 6 0 HEAT repeat Ipi1_N PF12333.3 EGD96098.1 - 0.066 13.1 3.6 26 4.8 0.0 4.6 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 EGD96098.1 - 0.079 13.4 13.4 29 5.3 0.0 7.3 7 1 0 7 7 7 0 HEAT-like repeat Fasciclin PF02469.17 EGD96099.1 - 0.0017 18.3 0.0 0.003 17.5 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain DUF106 PF01956.11 EGD96100.1 - 4.2e-54 182.5 1.5 5.2e-54 182.2 1.1 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 SPC25 PF06703.6 EGD96101.1 - 4.2e-42 143.4 0.2 4.8e-42 143.2 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) THF_DHG_CYH PF00763.18 EGD96102.1 - 3.6e-18 65.7 0.0 5.8e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EGD96102.1 - 1.1e-13 50.5 0.0 2.8e-09 36.2 0.0 2.8 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.20 EGD96103.1 - 1.2e-71 240.6 0.0 1.9e-71 240.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGD96103.1 - 2.1e-25 89.4 0.2 7.8e-25 87.5 0.1 2.1 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGD96103.1 - 1.8e-15 56.8 2.5 4.8e-15 55.5 1.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EGD96103.1 - 0.018 14.9 0.9 0.049 13.5 0.4 1.9 2 0 0 2 2 2 0 HAS barrel domain AAA_25 PF13481.1 EGD96103.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF962 PF06127.6 EGD96104.1 - 4.1e-26 90.7 0.0 7.1e-26 89.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.12 EGD96105.1 - 8.9e-14 51.3 0.1 1.4e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EGD96105.1 - 0.00052 20.0 0.0 0.00086 19.3 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain SnoaL PF07366.7 EGD96106.1 - 0.00044 19.8 0.3 0.02 14.4 0.0 2.9 2 1 0 2 2 2 1 SnoaL-like polyketide cyclase Fungal_trans PF04082.13 EGD96107.1 - 1.7e-15 56.6 0.1 3.1e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD96107.1 - 5.8e-07 29.3 12.4 1.3e-06 28.2 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 EGD96107.1 - 0.021 14.3 0.2 0.043 13.4 0.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 RRM_1 PF00076.17 EGD96108.1 - 4.2e-33 112.8 0.0 2.7e-18 65.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD96108.1 - 6.9e-24 83.6 0.0 1.2e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD96108.1 - 8e-14 51.2 0.0 9.6e-09 34.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGD96108.1 - 0.0085 15.9 0.1 0.08 12.8 0.0 2.4 2 1 0 2 2 2 1 RNA binding motif TPR_1 PF00515.23 EGD96109.1 - 1.1e-26 91.3 1.9 2.4e-09 36.3 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGD96109.1 - 1.5e-26 91.8 5.0 3.3e-11 42.6 0.1 4.5 2 2 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 EGD96109.1 - 1.1e-24 84.3 2.8 1.3e-07 30.9 0.0 6.0 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGD96109.1 - 1e-19 69.2 2.9 3.5e-05 24.0 0.0 5.7 4 1 2 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGD96109.1 - 2e-17 61.8 1.9 0.00081 19.4 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGD96109.1 - 5.4e-17 61.9 5.7 1.1e-05 25.9 0.0 4.8 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGD96109.1 - 1.4e-15 57.3 1.7 0.0004 20.6 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGD96109.1 - 2.3e-14 53.0 2.4 2.5e-08 33.7 0.1 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGD96109.1 - 2.6e-14 51.8 0.1 3.3e-05 23.3 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD96109.1 - 2.2e-11 42.6 2.1 0.00061 19.3 0.0 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 EGD96109.1 - 8.5e-11 41.8 0.5 0.0018 18.3 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGD96109.1 - 2.4e-09 36.9 1.1 0.0053 16.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGD96109.1 - 4e-07 30.0 2.1 1.6 9.3 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EGD96109.1 - 6e-07 29.5 0.4 0.00025 21.1 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EGD96109.1 - 0.0012 18.0 0.3 1 8.3 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 EGD96109.1 - 0.0018 18.0 0.0 3 7.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGD96109.1 - 0.0018 18.1 0.5 0.45 10.5 0.1 3.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TOM20_plant PF06552.7 EGD96109.1 - 0.036 13.6 0.1 3.7 7.0 0.0 3.0 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 MIT PF04212.13 EGD96109.1 - 0.046 13.5 1.3 2.7 7.9 0.3 3.8 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF4192 PF13830.1 EGD96109.1 - 1.1 8.8 7.0 1.4 8.4 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) TPP_enzyme_N PF02776.13 EGD96110.1 - 1.6e-44 151.4 0.2 3.3e-44 150.4 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGD96110.1 - 4.5e-33 113.9 0.0 8.4e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EGD96110.1 - 1.8e-18 66.5 0.0 4.2e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EGD96110.1 - 0.034 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit ERO1 PF04137.10 EGD96111.1 - 1.5e-133 445.2 0.1 2.9e-133 444.3 0.0 1.5 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) GST_C PF00043.20 EGD96112.1 - 1.8e-08 34.2 0.0 2.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD96112.1 - 1e-06 28.7 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGD96112.1 - 1.6e-06 28.2 0.0 5.6e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD96112.1 - 0.00043 20.2 0.0 0.00083 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD96112.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EGD96112.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Peroxin-13_N PF04088.8 EGD96113.1 - 1.2e-57 194.2 0.0 2.1e-57 193.5 0.0 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EGD96113.1 - 3.7e-09 35.9 0.0 6.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGD96113.1 - 7.5e-08 31.6 0.0 1.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD96113.1 - 2e-06 27.2 0.1 3.3e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Aminotran_5 PF00266.14 EGD96114.1 - 2.2e-30 105.6 0.0 3.4e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V APG6 PF04111.7 EGD96115.1 - 9.7e-129 428.9 0.4 1.2e-128 428.6 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF972 PF06156.8 EGD96115.1 - 0.024 14.9 1.4 0.055 13.8 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) YlqD PF11068.3 EGD96115.1 - 0.7 9.9 4.8 2.4 8.1 3.3 1.9 1 0 0 1 1 1 0 YlqD protein Scm3 PF10384.4 EGD96116.1 - 3.9e-24 83.8 0.1 6.6e-24 83.1 0.1 1.4 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-bind_6 PF13921.1 EGD96116.1 - 0.0002 21.3 2.0 0.23 11.6 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain PALP PF00291.20 EGD96117.1 - 1.4e-52 178.8 1.0 1.9e-52 178.3 0.7 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme rve PF00665.21 EGD96117.1 - 0.11 12.6 0.0 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain Methyltransf_28 PF02636.12 EGD96118.1 - 2e-37 128.9 0.0 3.5e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pathogen_betaC1 PF09593.5 EGD96118.1 - 0.14 11.9 0.3 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein Pal1 PF08316.6 EGD96119.1 - 2.6e-06 27.9 0.3 4.6e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Pal1 cell morphology protein Terpene_synth_C PF03936.11 EGD96120.1 - 1.3e-12 47.5 0.4 1.8e-12 47.0 0.3 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain HVSL PF09749.4 EGD96121.1 - 1.6e-75 253.2 0.0 1.9e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3807 PF12720.2 EGD96122.1 - 2.3e-37 128.8 3.3 2.7e-37 128.5 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) DUF4640 PF15480.1 EGD96123.1 - 0.044 13.3 1.3 0.048 13.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) Casc1 PF12366.3 EGD96123.1 - 0.09 12.2 0.3 0.094 12.2 0.2 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 SAS4 PF15460.1 EGD96126.1 - 2e-33 114.2 4.7 2e-33 114.2 3.3 2.3 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 TFIIF_alpha PF05793.7 EGD96126.1 - 0.0034 15.8 20.8 0.0058 15.0 14.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-B_dimeris PF09026.5 EGD96126.1 - 0.08 13.1 13.6 0.19 11.9 9.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain VID27 PF08553.5 EGD96126.1 - 0.56 8.3 11.1 0.87 7.7 7.7 1.4 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 EGD96126.1 - 0.58 8.0 23.0 0.96 7.2 15.9 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGD96126.1 - 1.1 7.1 15.7 2.2 6.1 10.9 1.4 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 EGD96126.1 - 5.5 5.8 12.3 11 4.9 8.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PX PF00787.19 EGD96127.1 - 1.5e-14 53.7 0.0 2.8e-14 52.8 0.0 1.4 2 0 0 2 2 2 1 PX domain Brix PF04427.13 EGD96129.1 - 4.2e-29 101.5 0.0 5.7e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain SH3_9 PF14604.1 EGD96130.1 - 2.1e-32 110.4 2.9 3.8e-16 58.3 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EGD96130.1 - 1.3e-29 101.3 4.3 1.1e-14 53.5 0.3 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EGD96130.1 - 6.3e-17 60.8 0.1 3.6e-08 32.7 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 EGD96130.1 - 2.3e-10 40.4 0.0 4.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Dynamin_M PF01031.15 EGD96131.1 - 1.8e-114 381.5 0.0 3.1e-114 380.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EGD96131.1 - 3.4e-56 189.6 1.1 1.8e-55 187.2 0.0 2.5 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 EGD96131.1 - 6.5e-32 109.2 1.0 1.6e-31 108.0 0.7 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGD96131.1 - 0.00033 20.6 0.4 0.0022 17.9 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD96131.1 - 0.0053 17.2 0.0 0.015 15.7 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein zf-CCHC_4 PF14392.1 EGD96131.1 - 0.12 12.0 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2 PF00096.21 EGD96132.1 - 0.0065 16.7 5.9 0.0065 16.7 4.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD96132.1 - 8.5 6.9 23.7 0.046 14.0 2.7 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger AAA PF00004.24 EGD96136.1 - 6.7e-48 162.2 0.0 8.4e-43 145.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGD96136.1 - 3.2e-06 27.9 0.0 0.0013 19.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGD96136.1 - 1.2e-05 24.8 0.1 0.00047 19.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGD96136.1 - 0.00012 22.2 0.0 0.0059 16.7 0.0 3.1 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EGD96136.1 - 0.00013 21.0 0.0 0.00042 19.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 EGD96136.1 - 0.00042 19.2 0.0 0.00078 18.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 EGD96136.1 - 0.00051 20.0 0.3 0.027 14.4 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 EGD96136.1 - 0.0014 18.8 0.1 0.013 15.6 0.0 2.6 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.12 EGD96136.1 - 0.0014 18.1 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EGD96136.1 - 0.0022 17.9 0.0 0.0066 16.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EGD96136.1 - 0.0026 17.0 0.0 0.083 12.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EGD96136.1 - 0.0046 16.6 0.1 0.027 14.2 0.0 2.4 2 0 0 2 2 1 1 Part of AAA domain TIP49 PF06068.8 EGD96136.1 - 0.0051 15.5 0.0 0.0089 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EGD96136.1 - 0.019 14.1 0.1 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGD96136.1 - 0.023 14.4 0.0 0.075 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EGD96136.1 - 0.025 13.6 0.0 0.067 12.2 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 EGD96136.1 - 0.027 14.7 0.0 0.094 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGD96136.1 - 0.037 13.8 0.0 0.27 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EGD96136.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGD96136.1 - 0.083 12.7 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.12 EGD96136.1 - 0.25 9.8 0.0 0.4 9.2 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase TPR_10 PF13374.1 EGD96137.1 - 4.4e-45 150.3 20.7 4.9e-11 42.1 0.1 7.6 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 EGD96137.1 - 3.2e-40 135.9 20.0 2.1e-16 59.5 0.9 5.6 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EGD96137.1 - 5.6e-14 50.8 18.5 0.00032 20.3 0.1 6.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGD96137.1 - 5e-13 48.4 20.2 0.00024 20.6 3.3 5.2 4 1 1 5 5 5 5 TPR repeat TPR_16 PF13432.1 EGD96137.1 - 8.2e-10 39.0 14.5 0.032 14.9 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGD96137.1 - 2.2e-09 36.4 19.8 0.00069 19.2 0.0 7.6 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGD96137.1 - 8e-09 34.7 17.2 4.1e-05 23.0 0.2 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD96137.1 - 4.5e-07 29.9 5.5 3e-05 24.0 0.2 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGD96137.1 - 1.1e-06 28.6 8.9 4.4 8.2 0.0 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGD96137.1 - 6.4e-05 22.8 7.0 0.77 10.1 0.2 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 EGD96137.1 - 0.00033 20.8 1.0 5 7.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Rab5-bind PF09311.6 EGD96137.1 - 0.0063 16.4 3.1 0.1 12.5 0.4 3.2 3 1 1 4 4 4 1 Rabaptin-like protein DUF386 PF04074.7 EGD96137.1 - 0.038 13.4 0.2 0.24 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF386) DUF627 PF04781.7 EGD96137.1 - 0.086 12.4 0.7 4.6 6.8 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF627) TPR_8 PF13181.1 EGD96137.1 - 0.2 11.5 16.5 14 5.7 0.1 6.7 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGD96137.1 - 0.84 10.0 15.5 1.3 9.4 1.0 4.4 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 EGD96137.1 - 1.6 8.5 4.6 0.86 9.4 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4243 PF14027.1 EGD96138.1 - 1.1e-78 265.0 0.8 1.3e-78 264.7 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) HECT_2 PF09814.4 EGD96140.1 - 3.1e-30 105.1 0.0 3.6e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF4403 PF14356.1 EGD96140.1 - 0.056 11.7 0.0 0.072 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) HECT_2 PF09814.4 EGD96141.1 - 5.6e-27 94.3 0.1 6.4e-27 94.1 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF1496 PF07383.7 EGD96141.1 - 0.043 13.0 0.1 0.5 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1496) CwfJ_C_2 PF04676.9 EGD96143.1 - 0.026 15.0 0.1 0.1 13.0 0.1 1.9 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 2 PI-PLC-X PF00388.14 EGD96144.1 - 1.1e-53 180.5 0.6 1.4e-39 134.7 0.0 2.5 2 0 0 2 2 2 2 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EGD96144.1 - 9e-37 125.6 0.0 1.8e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain DPPIV_N PF00930.16 EGD96146.1 - 8.2e-100 333.8 0.7 1.3e-99 333.1 0.5 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EGD96146.1 - 1.1e-56 191.4 5.2 1.1e-56 191.4 3.6 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGD96146.1 - 2.1e-09 37.2 0.0 6.4e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PBP1_TM PF14812.1 EGD96146.1 - 1.9e-07 31.2 0.0 4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S15 PF02129.13 EGD96146.1 - 9.5e-06 25.2 0.9 3.8e-05 23.2 0.4 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EGD96146.1 - 2.7e-05 24.1 0.0 0.00047 20.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGD96146.1 - 0.019 14.4 0.2 0.057 12.8 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 EGD96146.1 - 0.085 12.2 0.2 5.6 6.3 0.2 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FAD_binding_2 PF00890.19 EGD96147.1 - 1.9e-125 419.0 3.9 2.3e-125 418.7 2.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EGD96147.1 - 2.5e-47 159.9 1.3 3.8e-47 159.3 0.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EGD96147.1 - 4.7e-07 29.8 0.0 0.0015 18.4 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGD96147.1 - 6.3e-06 25.2 1.1 0.011 14.5 1.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EGD96147.1 - 1.2e-05 24.5 0.3 0.015 14.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EGD96147.1 - 9.3e-05 21.4 0.8 0.0019 17.1 0.6 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGD96147.1 - 0.0038 16.3 0.2 0.011 14.8 0.1 1.8 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGD96147.1 - 0.22 9.9 1.9 0.83 8.0 0.6 2.4 3 0 0 3 3 3 0 HI0933-like protein AAA PF00004.24 EGD96148.1 - 4.7e-41 140.0 0.0 8.2e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD96148.1 - 5e-06 26.6 0.0 0.00059 19.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGD96148.1 - 4.5e-05 23.1 0.1 0.00026 20.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGD96148.1 - 0.00018 21.5 0.0 0.00059 19.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGD96148.1 - 0.0002 21.4 0.0 0.00082 19.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EGD96148.1 - 0.0025 16.7 0.0 0.0045 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EGD96148.1 - 0.0032 18.2 0.1 0.013 16.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGD96148.1 - 0.009 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGD96148.1 - 0.0098 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EGD96148.1 - 0.017 15.1 0.1 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGD96148.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGD96148.1 - 0.036 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGD96148.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EGD96148.1 - 0.055 13.0 0.1 0.65 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EGD96148.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EGD96148.1 - 0.077 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EGD96148.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EGD96148.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Cpn60_TCP1 PF00118.19 EGD96149.1 - 2.4e-135 451.8 10.8 3e-135 451.5 7.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DeoC PF01791.4 EGD96149.1 - 0.04 13.2 1.4 1.4 8.1 0.1 3.0 3 0 0 3 3 3 0 DeoC/LacD family aldolase DUF3924 PF13062.1 EGD96149.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) P12 PF12669.2 EGD96150.1 - 0.013 15.6 0.6 0.013 15.6 0.4 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family Lysis_S PF04971.7 EGD96150.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Lysis protein S TMEM154 PF15102.1 EGD96150.1 - 0.15 11.7 4.6 0.71 9.5 2.9 2.4 1 1 0 1 1 1 0 TMEM154 protein family Ribosomal_L37 PF08561.5 EGD96151.1 - 1e-21 76.3 0.3 1.5e-21 75.6 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 NMT1 PF09084.6 EGD96152.1 - 4.8e-76 255.1 0.0 6.4e-76 254.7 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EGD96152.1 - 4.1e-09 36.1 0.1 0.0034 16.7 0.0 3.2 3 0 0 3 3 3 3 NMT1-like family RRM_1 PF00076.17 EGD96155.1 - 5.2e-40 134.9 0.0 3.7e-19 68.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD96155.1 - 1.1e-36 124.6 0.0 4.5e-19 68.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD96155.1 - 2.5e-22 78.4 0.0 8.7e-12 44.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EGD96155.1 - 0.004 15.6 54.7 0.0049 15.4 37.9 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Alg6_Alg8 PF03155.10 EGD96156.1 - 9.7e-129 430.2 19.0 1.9e-79 267.6 3.5 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family EpsG PF14897.1 EGD96156.1 - 0.22 10.3 8.5 0.063 12.1 3.4 1.8 1 1 1 2 2 2 0 EpsG family COX17 PF05051.8 EGD96157.1 - 3.6e-20 71.7 5.3 4.5e-20 71.3 3.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EGD96157.1 - 0.0064 16.2 3.0 0.026 14.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like LRR_6 PF13516.1 EGD96158.1 - 1e-11 43.6 4.7 0.17 12.0 0.0 7.9 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.2 EGD96158.1 - 2.7e-08 33.2 5.2 0.067 12.8 0.5 5.2 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGD96158.1 - 7.7e-05 22.2 8.5 38 4.8 0.0 7.4 8 1 1 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.1 EGD96158.1 - 0.00085 19.0 4.4 2.2 8.0 0.0 5.1 4 2 3 7 7 7 2 Leucine rich repeat LRR_7 PF13504.1 EGD96158.1 - 0.026 14.6 3.7 3.2e+02 2.3 0.0 6.5 8 0 0 8 8 7 0 Leucine rich repeat Nop14 PF04147.7 EGD96158.1 - 0.36 8.6 27.8 0.47 8.3 19.3 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.6 EGD96158.1 - 0.52 9.8 18.7 0.79 9.2 12.9 1.2 1 0 0 1 1 1 0 PPP4R2 Pox_RNA_Pol_19 PF05320.7 EGD96158.1 - 2.4 7.8 14.2 5.2 6.7 9.8 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PRTP PF01366.13 EGD96158.1 - 2.8 5.8 8.7 4.1 5.2 6.1 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Sigma70_ner PF04546.8 EGD96158.1 - 3.7 7.1 23.7 5.9 6.4 15.7 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Daxx PF03344.10 EGD96158.1 - 4.6 5.5 25.0 6.8 5.0 17.3 1.3 1 0 0 1 1 1 0 Daxx Family MBOAT_2 PF13813.1 EGD96159.1 - 8.7e-17 60.9 0.3 2.3e-16 59.6 0.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Sec10 PF07393.6 EGD96160.1 - 7.3e-234 778.1 0.0 8.6e-234 777.9 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 TFIIS_M PF07500.9 EGD96163.1 - 8.5e-29 99.9 0.9 8.5e-29 99.9 0.7 1.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EGD96163.1 - 1.2e-18 66.4 4.5 1.9e-18 65.8 3.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EGD96163.1 - 1.5e-14 53.1 0.4 3.6e-14 51.9 0.3 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Chordopox_A33R PF05966.7 EGD96163.1 - 0.025 13.3 0.0 0.065 12.0 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Baculo_LEF5_C PF11792.3 EGD96163.1 - 0.026 13.9 1.3 0.063 12.6 0.9 1.7 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Cytochrome_C554 PF13435.1 EGD96163.1 - 0.073 13.1 1.7 0.25 11.4 1.2 1.8 1 0 0 1 1 1 0 Cytochrome c554 and c-prime DAP10 PF07213.6 EGD96166.1 - 0.28 10.9 3.4 0.18 11.5 1.0 1.7 1 1 1 2 2 2 0 DAP10 membrane protein Macoilin PF09726.4 EGD96167.1 - 0.38 8.9 17.0 0.6 8.3 11.8 1.2 1 0 0 1 1 1 0 Transmembrane protein BNR PF02012.15 EGD96168.1 - 4.1e-07 28.8 25.5 0.92 9.5 0.0 9.6 10 0 0 10 10 10 5 BNR/Asp-box repeat BNR_2 PF13088.1 EGD96168.1 - 0.00015 21.1 0.9 0.66 9.2 0.0 4.6 4 2 2 6 6 6 2 BNR repeat-like domain DUF2167 PF09935.4 EGD96168.1 - 0.17 10.6 0.0 0.45 9.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) Transp_cyt_pur PF02133.10 EGD96169.1 - 2.8e-94 316.1 36.4 3.4e-94 315.8 25.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin dCMP_cyt_deam_1 PF00383.17 EGD96170.1 - 2.2e-16 59.3 0.8 2.6e-16 59.1 0.6 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EGD96170.1 - 3.7e-07 30.1 1.6 1e-06 28.7 0.1 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EGD96170.1 - 2.9e-05 23.5 3.4 0.00053 19.4 0.2 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Mito_carr PF00153.22 EGD96171.1 - 1.6e-63 210.4 1.8 5.2e-21 74.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.9 EGD96172.1 - 4.4e-39 133.0 31.7 5.5e-39 132.6 22.0 1.1 1 0 0 1 1 1 1 Cgr1 family CAF-1_p150 PF11600.3 EGD96172.1 - 0.16 11.3 27.2 0.19 11.0 18.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Metal_resist PF13801.1 EGD96172.1 - 1.5 8.8 8.7 1.9 8.4 6.0 1.2 1 0 0 1 1 1 0 Heavy-metal resistance DUF501 PF04417.7 EGD96172.1 - 4.2 7.2 8.0 6.4 6.6 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) TMPIT PF07851.8 EGD96172.1 - 9.5 5.1 6.5 11 5.0 4.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein SUI1 PF01253.17 EGD96174.1 - 2e-22 78.7 0.2 3.6e-22 77.9 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EGD96174.1 - 0.0028 17.5 0.1 0.0048 16.7 0.1 1.3 1 0 0 1 1 1 1 Transposon-encoded protein TnpV SRP14 PF02290.10 EGD96174.1 - 0.031 14.1 0.3 0.054 13.4 0.2 1.5 1 0 0 1 1 1 0 Signal recognition particle 14kD protein DUF1752 PF08550.5 EGD96176.1 - 6.6e-09 35.1 1.9 1.6e-08 33.9 1.3 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ELMO_CED12 PF04727.8 EGD96177.1 - 4.8e-49 166.1 0.2 8.6e-49 165.3 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EGD96177.1 - 1.1e-05 25.2 0.5 0.00013 21.7 0.3 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) FliD_N PF02465.13 EGD96177.1 - 0.04 14.2 0.1 0.16 12.3 0.1 2.0 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF4257 PF14074.1 EGD96177.1 - 0.075 12.6 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) Rad17 PF03215.10 EGD96178.1 - 4e-54 184.1 0.0 6.3e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EGD96178.1 - 0.00084 20.1 0.5 0.0033 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGD96178.1 - 0.00088 19.5 2.4 0.022 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGD96178.1 - 0.0015 18.2 0.0 0.0041 16.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EGD96178.1 - 0.0036 17.3 0.0 0.0083 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 EGD96178.1 - 0.004 16.7 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGD96178.1 - 0.0043 17.0 0.0 0.0043 17.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGD96178.1 - 0.0057 16.3 0.0 0.019 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EGD96178.1 - 0.0088 16.2 0.1 0.073 13.2 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EGD96178.1 - 0.011 14.6 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EGD96178.1 - 0.061 13.1 0.3 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGD96178.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGD96178.1 - 0.17 12.2 1.7 0.29 11.4 0.0 2.3 3 0 0 3 3 3 0 ABC transporter NB-ARC PF00931.17 EGD96178.1 - 0.2 10.4 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain UAA PF08449.6 EGD96179.1 - 1.5e-69 234.2 11.7 2.4e-69 233.5 8.1 1.3 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGD96179.1 - 0.00025 20.7 12.7 0.00025 20.7 8.8 3.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF791 PF05631.9 EGD96180.1 - 1.2e-63 214.9 5.4 1.8e-63 214.4 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EGD96180.1 - 1.6e-19 69.8 32.3 4.9e-19 68.2 10.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD96180.1 - 3.5e-12 45.6 3.9 3.5e-12 45.6 2.7 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 EGD96180.1 - 0.0093 15.7 0.2 0.083 12.6 0.0 2.6 2 0 0 2 2 2 1 MFS_1 like family Crystall_3 PF08964.5 EGD96181.1 - 0.062 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Beta/Gamma crystallin Hydrolase_6 PF13344.1 EGD96182.1 - 6.8e-21 74.0 0.0 2.3e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD96182.1 - 2.9e-16 58.9 0.0 7.3e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EGD96182.1 - 0.0055 16.9 0.0 1.2 9.2 0.0 2.9 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGD96182.1 - 0.014 15.8 0.0 0.44 10.9 0.0 2.9 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Apt1 PF10351.4 EGD96182.1 - 0.079 11.8 0.4 0.12 11.1 0.0 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Aldo_ket_red PF00248.16 EGD96183.1 - 4.9e-58 196.2 0.0 5.8e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TnpV PF14198.1 EGD96183.1 - 0.0062 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Transposon-encoded protein TnpV DUF3818 PF12825.2 EGD96184.1 - 2.9e-136 453.6 4.9 4.1e-136 453.1 3.4 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EGD96184.1 - 3.9e-43 146.3 0.2 8.1e-43 145.3 0.1 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EGD96184.1 - 1e-13 51.0 0.3 1.9e-12 46.9 0.0 3.0 2 1 0 2 2 2 1 PX domain zf-GRF PF06839.7 EGD96185.1 - 3.3e-11 42.9 4.2 5.9e-11 42.1 2.9 1.4 1 0 0 1 1 1 1 GRF zinc finger Met_10 PF02475.11 EGD96187.1 - 3.3e-67 225.9 0.0 4.8e-67 225.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein RNA_pol_Rpb4 PF03874.11 EGD96188.1 - 1.9e-23 82.7 2.7 2.3e-23 82.4 1.8 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF4102 PF13356.1 EGD96188.1 - 0.062 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) DUF2312 PF10073.4 EGD96188.1 - 0.13 11.6 0.7 0.42 9.9 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) AMP-binding PF00501.23 EGD96189.1 - 4.5e-69 232.8 0.0 6.6e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD96189.1 - 5.8e-10 39.9 0.0 1.1e-09 39.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RhoGAP PF00620.22 EGD96190.1 - 3.1e-33 114.5 0.1 6.1e-33 113.5 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EGD96190.1 - 4.5e-29 100.3 34.8 3.2e-12 46.3 4.6 5.0 5 0 0 5 5 5 4 LIM domain Nbl1_Borealin_N PF10444.4 EGD96191.1 - 4e-22 77.3 5.9 7.2e-22 76.5 4.1 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 EGD96192.1 - 2.1e-05 24.6 0.0 2.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EGD96192.1 - 0.00098 18.5 0.3 0.0028 17.1 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Phage_Gp23 PF10669.4 EGD96192.1 - 0.92 9.6 3.2 1.5 8.9 2.2 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Sybindin PF04099.7 EGD96193.1 - 3e-46 156.6 0.0 4.6e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EGD96193.1 - 3.1e-07 30.3 0.0 8.7e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region UQ_con PF00179.21 EGD96194.1 - 2.2e-36 124.3 0.0 3.8e-25 87.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD96194.1 - 3.8e-07 29.9 0.0 0.0033 17.1 0.0 2.3 2 0 0 2 2 2 2 Prokaryotic E2 family B RWD PF05773.17 EGD96194.1 - 0.00028 20.7 0.0 0.32 10.9 0.0 2.6 2 1 0 2 2 2 2 RWD domain FGE-sulfatase PF03781.11 EGD96197.1 - 1.9e-31 109.4 0.1 2.9e-31 108.7 0.1 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EGD96197.1 - 7.2e-08 32.8 0.3 1.4e-07 31.8 0.2 1.5 1 0 0 1 1 1 1 DinB superfamily Methyltransf_18 PF12847.2 EGD96197.1 - 2.6e-06 27.9 0.0 1.3e-05 25.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD96197.1 - 0.00039 20.7 0.0 0.0032 17.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD96197.1 - 0.0024 18.3 0.0 0.015 15.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain NAS PF03059.11 EGD96197.1 - 0.17 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein Gln-synt_C PF00120.19 EGD96198.1 - 1.8e-36 125.6 0.0 3.9e-36 124.5 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain IDO PF01231.13 EGD96199.1 - 2.4e-40 138.2 0.0 3.4e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase APH PF01636.18 EGD96200.1 - 2.7e-11 43.6 0.0 2.9e-10 40.2 0.0 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family SH3_8 PF13457.1 EGD96200.1 - 0.072 13.2 0.3 0.17 12.1 0.2 1.5 1 0 0 1 1 1 0 SH3-like domain DUF4208 PF13907.1 EGD96200.1 - 0.26 11.5 0.1 0.26 11.5 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) 3Beta_HSD PF01073.14 EGD96201.1 - 9.5e-47 159.0 0.0 1.2e-41 142.2 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGD96201.1 - 4.1e-17 62.4 0.0 5.1e-16 58.8 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGD96201.1 - 2e-12 46.5 0.0 2.6e-10 39.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EGD96201.1 - 2.6e-05 23.2 0.0 0.00012 21.1 0.0 2.0 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGD96201.1 - 8.7e-05 22.5 0.0 0.0018 18.3 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding HMG_CoA_synt_C PF08540.5 EGD96202.1 - 1e-96 323.7 3.2 1.2e-96 323.4 2.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EGD96202.1 - 4.5e-87 290.0 0.0 6.4e-87 289.5 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Pkinase PF00069.20 EGD96203.1 - 2.7e-61 207.0 0.0 8.9e-40 136.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96203.1 - 7.5e-29 100.5 0.0 5.1e-21 74.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EGD96203.1 - 9.6e-12 44.9 0.0 2.2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EGD96203.1 - 3.9e-08 32.5 0.1 4.8e-06 25.7 0.0 2.9 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EGD96203.1 - 5.6e-06 26.2 0.1 0.0056 16.4 0.1 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EGD96203.1 - 0.0045 16.0 0.0 0.0089 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 EGD96203.1 - 0.013 15.8 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAS PF00989.19 EGD96203.1 - 0.02 14.6 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 EGD96203.1 - 0.13 11.0 0.1 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 eIF-3_zeta PF05091.7 EGD96204.1 - 8.9e-187 621.8 0.0 1.1e-186 621.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) bZIP_1 PF00170.16 EGD96205.1 - 0.0024 17.7 4.4 0.0024 17.7 3.0 2.4 2 0 0 2 2 2 1 bZIP transcription factor Med9 PF07544.8 EGD96205.1 - 0.21 11.3 4.1 0.29 10.8 0.3 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_2 PF07716.10 EGD96205.1 - 4.4 7.1 12.8 0.48 10.2 3.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Nucleoplasmin PF03066.10 EGD96206.1 - 2.7 7.4 8.5 4.4 6.8 5.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Ins_P5_2-kin PF06090.7 EGD96207.1 - 1.1e-48 165.9 0.0 1.4e-46 159.0 0.0 2.1 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF4444 PF14563.1 EGD96207.1 - 0.019 14.3 0.1 0.067 12.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) Sec15 PF04091.7 EGD96208.1 - 3.6e-112 374.6 0.2 3.6e-112 374.6 0.1 2.7 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like COG2 PF06148.6 EGD96208.1 - 0.00087 19.1 5.0 0.00087 19.1 3.4 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2450 PF10475.4 EGD96208.1 - 0.0038 16.1 5.6 0.0098 14.8 3.9 1.7 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 EGD96208.1 - 0.044 13.5 6.5 0.077 12.7 1.7 2.9 3 0 0 3 3 3 0 Exocyst complex component Sec5 PMEI PF04043.10 EGD96208.1 - 0.13 12.2 1.8 0.18 11.6 0.4 1.8 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Sec8_exocyst PF04048.9 EGD96208.1 - 0.34 10.5 10.6 0.04 13.5 3.1 2.6 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain CBFD_NFYB_HMF PF00808.18 EGD96209.1 - 6.1e-19 67.8 0.5 1.1e-18 67.0 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGD96209.1 - 2.4e-12 46.8 0.1 3.7e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EGD96209.1 - 0.033 13.9 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TEA PF01285.13 EGD96209.1 - 0.06 12.5 0.8 0.098 11.7 0.5 1.4 1 0 0 1 1 1 0 TEA/ATTS domain family Fcf2 PF08698.6 EGD96211.1 - 3.8e-32 110.2 0.6 1.1e-31 108.7 0.4 1.8 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing DUF89 PF01937.14 EGD96211.1 - 0.029 13.1 0.0 0.045 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF89 PNP_UDP_1 PF01048.15 EGD96212.1 - 1.2e-51 174.9 0.1 1.7e-51 174.4 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S10 PF00338.17 EGD96213.1 - 1.1e-25 89.2 0.0 1.9e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e SAB PF04382.8 EGD96213.1 - 0.042 13.5 1.6 0.071 12.8 0.2 2.0 2 0 0 2 2 2 0 SAB domain DUF3579 PF12112.3 EGD96213.1 - 0.065 13.1 0.1 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3579) tRNA-synt_1b PF00579.20 EGD96214.1 - 1.5e-67 227.8 0.0 1.9e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TRL PF13146.1 EGD96214.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 TRL-like protein family SWIRM PF04433.12 EGD96218.1 - 2.4e-15 56.4 0.0 9.6e-15 54.4 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain CDC50 PF03381.10 EGD96219.1 - 2.1e-99 332.2 0.0 2.8e-99 331.7 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SPT16 PF08644.6 EGD96220.1 - 3.3e-59 199.1 0.1 7.9e-59 197.8 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EGD96220.1 - 9.6e-55 184.5 0.1 2.9e-54 182.9 0.1 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EGD96220.1 - 1.1e-24 87.1 0.0 1.7e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EGD96220.1 - 3.4e-19 68.5 0.0 9.4e-19 67.1 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like RST PF12174.3 EGD96220.1 - 0.2 11.5 1.2 0.42 10.4 0.8 1.5 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Mito_carr PF00153.22 EGD96221.1 - 9e-19 66.9 1.0 7e-12 44.8 0.0 3.3 3 0 0 3 3 3 2 Mitochondrial carrier protein Vma12 PF11712.3 EGD96222.1 - 0.072 12.7 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase GST_N_3 PF13417.1 EGD96223.1 - 1.9e-08 34.4 0.0 4.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD96223.1 - 3e-07 30.3 0.1 8.4e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD96223.1 - 8.6e-06 25.5 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD96223.1 - 0.00018 21.9 0.1 0.0003 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGD96223.1 - 0.00042 20.2 0.0 0.00083 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DBD_Tnp_Hermes PF10683.4 EGD96223.1 - 0.035 13.5 0.0 0.086 12.3 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain Sugar_tr PF00083.19 EGD96224.1 - 4.7e-101 338.5 16.1 5.6e-101 338.3 11.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD96224.1 - 8.5e-32 110.2 21.1 2e-31 108.9 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PMT PF02366.13 EGD96226.1 - 4e-84 281.8 17.4 4e-84 281.8 12.1 2.8 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGD96226.1 - 5.6e-39 133.6 0.1 7.7e-39 133.2 0.1 1.2 1 0 0 1 1 1 1 MIR domain CRISPR_Cse2 PF09485.5 EGD96228.1 - 0.04 13.9 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Rrp15p PF07890.7 EGD96228.1 - 0.097 12.7 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Rrp15p HLH PF00010.21 EGD96228.1 - 0.21 11.3 1.4 1.7 8.4 0.0 2.3 2 1 0 2 2 2 0 Helix-loop-helix DNA-binding domain Ras PF00071.17 EGD96230.1 - 9.8e-42 142.0 0.2 3.2e-36 124.1 0.0 3.1 3 0 0 3 3 3 3 Ras family Miro PF08477.8 EGD96230.1 - 1.9e-13 50.9 0.0 2.6e-10 40.8 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EGD96230.1 - 4.3e-09 35.8 0.0 3.6e-05 23.0 0.0 2.0 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Arf PF00025.16 EGD96230.1 - 1.1e-07 31.2 0.1 2.7e-07 29.9 0.1 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGD96230.1 - 2.8e-07 30.1 0.0 6.2e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGD96230.1 - 0.014 15.3 0.0 0.32 10.9 0.0 2.7 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EGD96230.1 - 0.042 13.9 0.1 0.31 11.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain DUF2201_N PF13203.1 EGD96230.1 - 0.065 12.3 0.1 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain AAA_16 PF13191.1 EGD96230.1 - 0.15 12.0 1.0 0.81 9.6 0.0 2.2 2 1 1 3 3 3 0 AAA ATPase domain FAM176 PF14851.1 EGD96230.1 - 0.34 10.5 3.2 0.57 9.8 2.2 1.2 1 0 0 1 1 1 0 FAM176 family Choline_transpo PF04515.7 EGD96232.1 - 9.8e-13 47.5 15.9 9.8e-13 47.5 11.0 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter Aldo_ket_red PF00248.16 EGD96235.1 - 3.2e-48 164.0 0.0 3.6e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 EGD96236.1 - 3.1e-122 408.3 0.0 3.9e-122 408.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF3296 PF11726.3 EGD96236.1 - 0.047 13.2 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) zf-CCHC PF00098.18 EGD96238.1 - 8.6e-44 145.4 55.1 2.7e-07 30.1 1.5 7.2 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EGD96238.1 - 7.1e-12 44.8 39.7 0.021 14.4 0.6 7.0 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EGD96238.1 - 0.00047 19.8 44.1 0.072 12.8 0.1 6.6 3 2 3 6 6 6 4 Zinc knuckle zf-CCHC_6 PF15288.1 EGD96238.1 - 0.026 14.2 42.1 0.19 11.4 0.3 6.8 3 2 4 7 7 7 0 Zinc knuckle F-box-like PF12937.2 EGD96239.1 - 2.8e-06 26.9 0.1 6.7e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD96239.1 - 4.4e-06 26.1 0.1 8.5e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EGD96239.1 - 0.0036 17.1 0.0 6.5 6.8 0.1 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat SAE2 PF08573.5 EGD96240.1 - 1.8e-23 83.0 2.8 3.2e-21 75.8 0.0 3.2 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus APG6 PF04111.7 EGD96240.1 - 0.0033 16.5 13.4 0.0051 15.9 9.3 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 EzrA PF06160.7 EGD96240.1 - 0.039 12.1 10.5 0.059 11.5 7.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Phage_GP20 PF06810.6 EGD96240.1 - 0.096 12.1 12.6 0.2 11.0 8.7 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 ATG16 PF08614.6 EGD96240.1 - 0.11 12.2 14.0 0.034 13.9 7.2 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Microtub_assoc PF07989.6 EGD96240.1 - 0.15 11.8 8.0 0.58 10.0 1.6 3.0 2 1 1 3 3 3 0 Microtubule associated Raffinose_syn PF05691.7 EGD96240.1 - 0.2 9.1 0.5 0.28 8.6 0.3 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 DUF4407 PF14362.1 EGD96240.1 - 0.3 10.0 5.2 0.53 9.1 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.6 EGD96240.1 - 0.42 10.5 2.2 0.49 10.3 0.4 1.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 EGD96240.1 - 0.7 9.4 8.7 0.35 10.3 3.8 2.0 1 1 1 2 2 2 0 Septum formation initiator TMPIT PF07851.8 EGD96240.1 - 1.3 8.0 7.0 2 7.4 4.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Snapin_Pallidin PF14712.1 EGD96240.1 - 1.5 9.1 9.8 5.1 7.4 1.3 2.6 1 1 1 2 2 2 0 Snapin/Pallidin DUF724 PF05266.9 EGD96240.1 - 1.5 8.3 10.0 3 7.4 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 EGD96240.1 - 1.5 6.5 2.5 2.2 6.0 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 EGD96240.1 - 3.6 7.4 16.1 5 7.0 4.6 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EGD96240.1 - 6.1 6.4 14.4 13 5.3 10.0 1.5 1 0 0 1 1 1 0 IncA protein Pex16 PF08610.5 EGD96241.1 - 1.3e-113 379.4 0.1 1.4e-113 379.2 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.13 EGD96242.1 - 7.8e-44 149.6 0.0 2.5e-41 141.5 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease HII CENP-C_C PF11699.3 EGD96243.1 - 2.5e-33 113.8 1.6 2.5e-33 113.8 1.1 2.0 2 0 0 2 2 2 1 Mif2/CENP-C like Mif2_N PF15624.1 EGD96243.1 - 2.5e-30 105.8 3.6 2.5e-30 105.8 2.5 3.7 3 1 0 3 3 3 2 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 EGD96243.1 - 2.1e-05 23.9 0.0 6.7e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 Cupin domain DUF2894 PF11445.3 EGD96243.1 - 0.81 9.9 5.3 0.47 10.6 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Ycf1 PF05758.7 EGD96243.1 - 4.2 4.9 7.2 5.5 4.5 5.0 1.3 1 0 0 1 1 1 0 Ycf1 CAP_GLY PF01302.20 EGD96244.1 - 4.2e-29 100.0 0.0 8.2e-29 99.1 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EGD96244.1 - 4.5e-16 58.8 0.0 8.9e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EGD96244.1 - 1.2e-06 27.7 0.0 6e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin family Methyltransf_11 PF08241.7 EGD96245.1 - 5.4e-12 46.0 0.0 9.4e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD96245.1 - 1.4e-07 31.3 0.0 3.7e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD96245.1 - 5e-06 26.1 0.0 6.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD96245.1 - 5e-05 23.7 0.0 9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD96245.1 - 5.6e-05 23.4 0.0 9.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD96245.1 - 0.001 19.6 0.0 0.0019 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EGD96245.1 - 0.077 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Myb_DNA-binding PF00249.26 EGD96247.1 - 2.1e-10 40.4 2.4 1.1e-07 31.8 0.1 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD96247.1 - 8.6e-08 32.1 5.1 0.00012 22.1 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Cofilin_ADF PF00241.15 EGD96249.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Herpes_U30 PF04523.8 EGD96249.1 - 0.14 9.5 0.0 0.17 9.3 0.0 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 UCH PF00443.24 EGD96251.1 - 9.3e-34 116.7 0.2 1.3e-33 116.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD96251.1 - 2.4e-22 79.7 0.1 4e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EGD96251.1 - 0.00027 20.3 3.4 0.025 13.8 0.2 3.1 2 1 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase IL22 PF14565.1 EGD96251.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor MitMem_reg PF13012.1 EGD96253.1 - 2.2e-39 134.0 0.4 4.2e-39 133.1 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EGD96253.1 - 7.8e-28 96.5 0.1 2.1e-27 95.1 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PGA2 PF07543.7 EGD96253.1 - 0.025 14.3 5.1 0.048 13.4 3.5 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 ADK PF00406.17 EGD96254.1 - 5.8e-61 204.7 0.1 7.4e-61 204.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EGD96254.1 - 1.8e-14 53.0 0.0 5.2e-14 51.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EGD96254.1 - 1.1e-05 25.2 0.0 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD96254.1 - 1.4e-05 25.8 0.1 2.7e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD96254.1 - 0.015 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGD96254.1 - 0.016 14.3 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Thymidylate_kin PF02223.12 EGD96254.1 - 0.13 11.6 0.1 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase Mucin PF01456.12 EGD96255.1 - 4.8 6.9 10.2 5.5 6.7 7.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein CFIA_Pcf11 PF11526.3 EGD96256.1 - 3.2e-05 23.9 2.1 3.2e-05 23.9 1.5 2.0 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.8 EGD96256.1 - 0.00063 19.9 0.0 0.0023 18.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.14 EGD96256.1 - 0.0022 17.6 0.0 0.0073 15.9 0.0 1.8 2 0 0 2 2 2 1 VHS domain RRN7 PF11781.3 EGD96256.1 - 0.063 12.7 2.2 0.68 9.4 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 MULE PF10551.4 EGD96256.1 - 0.15 12.2 0.0 15 5.8 0.0 2.4 2 0 0 2 2 2 0 MULE transposase domain zf-C2H2_6 PF13912.1 EGD96256.1 - 0.36 10.8 3.6 2.3 8.2 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ISL3 PF14690.1 EGD96256.1 - 1.6 8.7 3.9 0.73 9.9 0.4 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2HC_2 PF13913.1 EGD96256.1 - 2.7 7.7 4.9 13 5.5 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Inhibitor_I9 PF05922.11 EGD96257.1 - 0.00034 21.1 0.1 0.00056 20.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF3186 PF11382.3 EGD96257.1 - 0.0052 15.9 0.1 0.0059 15.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3186) HOOK PF05622.7 EGD96258.1 - 1.1e-21 76.3 33.0 1.1e-21 76.3 22.9 2.7 1 1 0 2 2 2 1 HOOK protein Coprogen_oxidas PF01218.13 EGD96259.1 - 4e-120 399.8 0.0 8.1e-120 398.8 0.0 1.5 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 EGD96260.1 - 2.9e-51 171.7 0.2 3.4e-51 171.5 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EGD96260.1 - 2.8e-06 27.4 0.0 3.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Mito_carr PF00153.22 EGD96262.1 - 3.8e-28 97.0 2.6 1e-14 53.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Apc15p PF05841.6 EGD96263.1 - 3.2e-22 79.5 0.0 3.2e-22 79.5 0.0 2.0 2 1 0 2 2 2 1 Apc15p protein SNARE PF05739.14 EGD96264.1 - 4.2e-08 32.7 0.8 5.4e-08 32.4 0.6 1.1 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EGD96264.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 CHZ PF09649.5 EGD96265.1 - 3.1e-13 48.7 0.3 3.1e-13 48.7 0.2 2.5 1 1 1 2 2 2 1 Histone chaperone domain CHZ HSP70 PF00012.15 EGD96266.1 - 2e-271 901.2 7.9 2.3e-271 901.0 5.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGD96266.1 - 1.5e-16 59.9 0.1 1.2e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EGD96266.1 - 0.0016 17.5 0.1 0.023 13.7 0.0 2.2 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EGD96266.1 - 0.0028 17.3 0.0 0.0077 15.8 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EGD96266.1 - 0.012 15.3 3.9 0.86 9.4 0.4 3.6 2 2 0 2 2 2 0 Cell division protein FtsA DUF1843 PF08898.5 EGD96266.1 - 2.7 8.0 5.8 1.2 9.2 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Fungal_trans PF04082.13 EGD96267.1 - 3.9e-25 88.1 0.8 6.1e-25 87.5 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD96267.1 - 0.01 15.6 13.4 0.017 15.0 9.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAX PF00292.13 EGD96267.1 - 0.017 14.8 0.8 0.11 12.2 0.7 1.9 2 0 0 2 2 2 0 'Paired box' domain DIOX_N PF14226.1 EGD96269.1 - 4.5e-30 104.5 0.1 1.1e-29 103.3 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGD96269.1 - 4e-17 62.3 0.0 6.9e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 EGD96270.1 - 1.1e-93 314.1 32.2 1.3e-93 313.9 22.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin McyA_C PF12593.3 EGD96270.1 - 0.037 13.7 0.1 0.078 12.7 0.1 1.5 1 0 0 1 1 1 0 Microcystin synthetase C terminal Glu_synthase PF01645.12 EGD96271.1 - 9.5e-159 528.1 0.0 1.7e-158 527.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EGD96271.1 - 1.1e-137 458.5 0.0 1.6e-137 458.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EGD96271.1 - 2.1e-119 398.0 0.0 3.5e-119 397.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EGD96271.1 - 1.6e-65 219.9 3.4 3.3e-65 218.8 2.3 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EGD96271.1 - 1.9e-22 78.9 0.0 4.9e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EGD96271.1 - 1.1e-16 61.2 0.0 3.5e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD96271.1 - 7e-11 42.5 1.1 0.00016 21.8 0.2 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD96271.1 - 8.8e-09 35.2 0.1 3.4e-08 33.3 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGD96271.1 - 1.6e-06 28.4 0.0 0.00089 19.6 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGD96271.1 - 3.9e-06 26.1 1.1 5.3e-06 25.7 0.2 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EGD96271.1 - 8.1e-06 24.9 1.3 0.00015 20.8 0.3 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD96271.1 - 2.7e-05 23.2 1.6 0.00018 20.4 0.6 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EGD96271.1 - 4.3e-05 22.7 0.3 9.3e-05 21.6 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGD96271.1 - 7e-05 21.4 0.4 7e-05 21.4 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EGD96271.1 - 0.0012 18.0 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGD96271.1 - 0.0025 16.9 0.1 0.0025 16.9 0.1 2.2 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 EGD96271.1 - 0.013 14.4 2.0 0.027 13.3 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EGD96271.1 - 0.02 14.4 0.2 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DJ-1_PfpI PF01965.19 EGD96271.1 - 0.044 13.2 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 1 0 DJ-1/PfpI family NAD_Gly3P_dh_N PF01210.18 EGD96271.1 - 0.093 12.4 0.1 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 EGD96271.1 - 0.11 12.7 2.0 6.5 7.0 0.1 2.8 3 0 0 3 3 2 0 Putative NAD(P)-binding MADF_DNA_bdg PF10545.4 EGD96271.1 - 0.19 11.9 0.6 0.54 10.4 0.4 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FMO-like PF00743.14 EGD96271.1 - 0.23 9.5 0.1 2.3 6.3 0.0 2.2 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like DUF3128 PF11326.3 EGD96272.1 - 2e-30 104.7 3.3 3.7e-30 103.8 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DUF605 PF04652.11 EGD96272.1 - 0.026 13.9 5.7 0.027 13.8 4.0 1.1 1 0 0 1 1 1 0 Vta1 like RNA12 PF10443.4 EGD96273.1 - 1.4e-154 514.7 0.3 2.1e-154 514.1 0.2 1.2 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EGD96273.1 - 0.00094 18.9 0.1 0.0064 16.2 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase DUF2487 PF10673.4 EGD96273.1 - 0.0039 16.9 0.0 0.0097 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) RRM_1 PF00076.17 EGD96273.1 - 0.008 15.7 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD96273.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 EGD96275.1 - 2.7e-06 26.1 0.0 0.0054 15.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 WD40 PF00400.27 EGD96276.1 - 4.1e-24 83.5 4.4 3.1e-10 39.5 0.0 8.1 7 1 1 8 8 8 4 WD domain, G-beta repeat DUF3639 PF12341.3 EGD96276.1 - 1.8e-09 37.3 1.2 1.8e-09 37.3 0.8 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 EGD96276.1 - 3.2e-09 36.0 0.2 1.4e-08 33.9 0.0 1.7 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 EGD96276.1 - 3.2e-05 23.7 0.6 0.00014 21.6 0.1 2.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EGD96276.1 - 0.00019 19.7 0.0 0.12 10.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) IKI3 PF04762.7 EGD96276.1 - 0.0011 16.8 0.2 0.0011 16.8 0.2 2.4 3 1 0 3 3 3 1 IKI3 family Apc4_WD40 PF12894.2 EGD96276.1 - 0.11 12.0 0.0 31 4.1 0.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_alpha_N PF12254.3 EGD96276.1 - 7.6 6.4 12.7 0.085 12.6 3.1 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal MFS_1 PF07690.11 EGD96278.1 - 3.3e-36 124.7 21.6 3.3e-36 124.7 14.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD96278.1 - 8.1e-06 24.6 8.8 8.1e-06 24.6 6.1 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter DUF791 PF05631.9 EGD96278.1 - 0.0024 16.6 1.4 0.0042 15.8 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) LacY_symp PF01306.14 EGD96278.1 - 0.0096 14.5 0.3 0.02 13.4 0.2 1.5 1 0 0 1 1 1 1 LacY proton/sugar symporter Sulfate_tra_GLY PF13792.1 EGD96278.1 - 0.016 14.8 3.1 0.016 14.8 2.1 3.3 3 1 0 3 3 3 0 Sulfate transporter N-terminal domain with GLY motif DUF1129 PF06570.6 EGD96278.1 - 0.4 9.9 3.2 10 5.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) DUF4298 PF14131.1 EGD96279.1 - 0.079 12.8 4.0 0.054 13.3 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DUF2347 PF09804.4 EGD96279.1 - 0.15 11.2 1.9 0.25 10.5 1.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) AAA_23 PF13476.1 EGD96279.1 - 0.48 10.7 7.5 0.81 9.9 5.2 1.3 1 0 0 1 1 1 0 AAA domain CBFD_NFYB_HMF PF00808.18 EGD96280.1 - 0.00088 19.2 0.1 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.1 EGD96280.1 - 0.058 13.3 0.2 0.12 12.3 0.2 1.7 1 1 0 1 1 1 0 Centromere kinetochore component W LpxB PF02684.10 EGD96280.1 - 0.093 11.3 0.1 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase VTC PF09359.5 EGD96281.1 - 3.8e-84 282.0 0.0 6.7e-84 281.2 0.0 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EGD96281.1 - 2.1e-22 80.1 5.7 7.5e-16 58.7 1.0 3.2 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 EGD96281.1 - 3.1e-10 40.1 1.7 3.1e-10 40.1 1.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) RAP1 PF07218.6 EGD96281.1 - 0.095 10.7 0.1 0.15 10.1 0.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-CpG_bind_C PF12269.3 EGD96281.1 - 0.26 10.7 1.3 0.56 9.6 0.6 1.6 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain 6PF2K PF01591.13 EGD96282.1 - 3.4e-46 157.1 0.0 5e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGD96282.1 - 2.8e-25 89.2 0.0 5.5e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF202 PF02656.10 EGD96283.1 - 0.00073 19.7 3.8 0.01 16.0 2.6 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF202) DUF3169 PF11368.3 EGD96283.1 - 0.045 12.9 0.2 0.054 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF998 PF06197.8 EGD96283.1 - 0.047 13.0 2.8 0.34 10.2 1.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF998) F-box PF00646.28 EGD96284.1 - 2.2e-06 27.1 0.0 4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD96284.1 - 5.6e-05 22.7 0.3 0.00013 21.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like FMN_dh PF01070.13 EGD96285.1 - 4.8e-101 338.1 0.0 6.5e-101 337.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EGD96285.1 - 4e-22 77.8 0.0 1.6e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 EGD96285.1 - 1.2e-06 27.6 0.3 0.0022 16.9 0.1 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EGD96285.1 - 8.7e-06 24.8 0.0 1.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ATP11 PF06644.6 EGD96285.1 - 0.0046 16.4 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 ATP11 protein NMO PF03060.10 EGD96285.1 - 0.042 12.9 2.3 0.097 11.8 0.1 2.2 1 1 1 2 2 2 0 Nitronate monooxygenase His_biosynth PF00977.16 EGD96285.1 - 0.062 12.5 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Cauli_VI PF01693.11 EGD96286.1 - 4.1e-34 116.3 4.8 2e-16 59.7 0.2 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EGD96286.1 - 4.5e-29 101.4 0.0 7.2e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 RNase H Na_H_Exchanger PF00999.16 EGD96288.1 - 7.9e-44 149.7 20.0 1e-43 149.3 13.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 7TM_GPCR_Srv PF10323.4 EGD96288.1 - 0.016 14.3 1.6 0.026 13.6 0.6 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv PhaG_MnhG_YufB PF03334.9 EGD96288.1 - 1.7 8.7 13.5 1.9 8.6 0.2 4.1 3 1 0 3 3 3 0 Na+/H+ antiporter subunit GFO_IDH_MocA PF01408.17 EGD96289.1 - 3.9e-17 62.8 0.0 6.2e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_23 PF13489.1 EGD96290.1 - 3.4e-17 62.6 0.0 6.1e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD96290.1 - 4.9e-09 35.9 0.0 2.4e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD96290.1 - 5.9e-09 36.4 0.0 5.5e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD96290.1 - 8.5e-08 32.5 0.0 4.6e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD96290.1 - 1.6e-06 28.4 0.0 3.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD96290.1 - 0.00018 21.4 0.0 0.0033 17.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGD96290.1 - 0.001 18.1 0.0 0.022 13.7 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EGD96290.1 - 0.0073 15.6 0.0 0.029 13.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 EGD96290.1 - 0.008 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EGD96290.1 - 0.0095 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EGD96290.1 - 0.023 15.0 0.0 0.055 13.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EGD96290.1 - 0.07 12.1 0.0 0.44 9.5 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EGD96290.1 - 0.074 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Ubie_methyltran PF01209.13 EGD96290.1 - 0.087 11.9 0.0 0.51 9.4 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family ERG4_ERG24 PF01222.12 EGD96291.1 - 2.9e-143 477.5 21.8 3.4e-143 477.2 15.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family zf-C3HC4_2 PF13923.1 EGD96292.1 - 6.4e-06 26.0 11.4 1.1e-05 25.3 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD96292.1 - 9.3e-06 25.2 9.4 1.8e-05 24.3 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD96292.1 - 7.7e-05 22.4 11.2 0.00016 21.4 7.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGD96292.1 - 0.00021 20.8 7.9 0.00035 20.1 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD96292.1 - 0.00046 19.8 7.2 0.00097 18.8 5.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGD96292.1 - 0.00049 19.9 9.1 0.0025 17.6 6.5 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD96292.1 - 0.45 10.2 9.1 1.1 9.0 6.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger UCH PF00443.24 EGD96293.1 - 5e-42 143.8 0.3 1.6e-37 129.0 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD96293.1 - 1.8e-20 73.5 0.0 3.8e-19 69.2 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DLH PF01738.13 EGD96294.1 - 6.8e-30 103.9 0.0 7.8e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGD96294.1 - 5.5e-06 26.2 0.0 7.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EGD96294.1 - 0.0041 16.8 0.0 0.095 12.3 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EGD96294.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2305 PF10230.4 EGD96294.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Chs3p PF12271.3 EGD96295.1 - 1.6e-102 342.4 7.8 2e-102 342.1 5.4 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit MpPF26 PF07666.6 EGD96295.1 - 0.015 15.1 4.1 0.015 15.1 2.8 3.0 3 2 1 4 4 4 0 M penetrans paralogue family 26 Lysis_S PF04971.7 EGD96295.1 - 0.023 14.3 0.1 0.089 12.4 0.0 2.0 1 0 0 1 1 1 0 Lysis protein S DUF202 PF02656.10 EGD96295.1 - 1.1 9.5 0.0 1.1 9.5 0.0 4.6 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Glyoxalase_2 PF12681.2 EGD96296.1 - 2.4e-09 37.7 0.1 3.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGD96296.1 - 4.9e-06 26.5 0.3 1.8e-05 24.7 0.2 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Imm32 PF15579.1 EGD96296.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 32 BC10 PF06726.7 EGD96297.1 - 3.9e-17 62.0 9.9 7.6e-17 61.0 6.9 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 EMP24_GP25L PF01105.19 EGD96298.1 - 4.8 6.8 6.2 52 3.4 1.1 3.2 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD dCMP_cyt_deam_1 PF00383.17 EGD96299.1 - 0.00021 20.8 0.0 0.00074 19.1 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Cyclin PF08613.6 EGD96300.1 - 7.2e-28 97.8 0.1 7.2e-28 97.8 0.1 2.4 2 2 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EGD96300.1 - 0.00027 20.5 0.0 0.00027 20.5 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIA PF03153.8 EGD96300.1 - 2.4 7.9 28.6 3.6 7.3 19.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Arm PF00514.18 EGD96301.1 - 2.1e-14 52.6 15.0 0.0012 18.5 0.3 8.4 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EGD96301.1 - 0.0084 16.1 14.3 1.2 9.4 0.1 6.8 7 0 0 7 7 7 2 HEAT repeat Ric8 PF10165.4 EGD96301.1 - 0.015 14.1 0.5 0.12 11.1 0.0 2.6 4 0 0 4 4 4 0 Guanine nucleotide exchange factor synembryn Fructosamin_kin PF03881.9 EGD96302.1 - 1.7e-74 250.4 0.0 7.1e-74 248.3 0.0 1.7 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EGD96302.1 - 2e-05 24.4 0.0 3.7e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3074 PF11274.3 EGD96302.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) GST_N_3 PF13417.1 EGD96303.1 - 2e-21 76.0 0.0 4.4e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD96303.1 - 1.8e-13 50.2 0.0 3.5e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD96303.1 - 0.017 15.2 0.0 0.044 13.9 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD96303.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-met PF12874.2 EGD96304.1 - 0.01 16.0 0.6 0.01 16.0 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EGD96304.1 - 0.01 16.1 3.8 0.074 13.4 0.1 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EGD96304.1 - 0.014 15.5 1.5 0.21 11.7 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF1610 PF07754.6 EGD96304.1 - 0.38 10.8 0.1 0.38 10.8 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1610) PhnA_Zn_Ribbon PF08274.7 EGD96304.1 - 0.46 10.3 5.0 7.8 6.3 3.6 2.3 1 1 0 1 1 1 0 PhnA Zinc-Ribbon zf-C2H2_6 PF13912.1 EGD96304.1 - 0.87 9.5 8.0 4.4 7.3 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-ribbon_3 PF13248.1 EGD96304.1 - 4.3 6.6 6.1 53 3.2 4.3 2.3 1 1 0 1 1 1 0 zinc-ribbon domain zf-C2H2_jaz PF12171.3 EGD96305.1 - 1e-05 25.5 42.8 0.019 15.1 0.6 7.2 5 2 2 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EGD96305.1 - 9.7e-05 22.4 40.5 0.032 14.5 0.4 7.4 6 1 1 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD96305.1 - 0.00041 20.5 47.3 0.0013 18.9 0.1 8.2 7 1 1 8 8 8 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EGD96305.1 - 0.0019 18.0 1.4 0.0019 18.0 1.0 6.2 6 0 0 6 6 6 1 C2H2-type zinc finger zf-met PF12874.2 EGD96305.1 - 0.0023 18.0 37.6 0.51 10.6 0.5 6.9 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EGD96305.1 - 0.033 14.2 37.4 0.93 9.6 4.9 4.3 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF1477 PF07346.6 EGD96305.1 - 0.21 11.6 7.1 2.3 8.3 0.2 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1477) Cyclin_N PF00134.18 EGD96306.1 - 4.7e-11 42.3 0.0 3.9e-09 36.1 0.0 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain CTP_transf_1 PF01148.15 EGD96307.1 - 4.9e-82 275.4 26.4 5.9e-82 275.2 18.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.3 EGD96308.1 - 7.1e-55 184.6 0.1 1.7e-54 183.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DUF1192 PF06698.6 EGD96308.1 - 0.0019 17.9 0.9 0.0052 16.5 0.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) DUF4164 PF13747.1 EGD96308.1 - 0.0093 16.0 0.6 0.0093 16.0 0.4 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) Takusan PF04822.8 EGD96308.1 - 0.27 11.0 5.9 0.048 13.4 0.6 2.3 2 0 0 2 2 2 0 Takusan CDC45 PF02724.9 EGD96309.1 - 0.3 9.0 15.7 0.29 9.1 10.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGD96309.1 - 0.32 8.8 21.8 0.29 8.9 15.1 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.6 EGD96309.1 - 2 7.8 23.0 2.4 7.6 15.9 1.1 1 0 0 1 1 1 0 PPP4R2 TAP42 PF04177.7 EGD96309.1 - 2.3 7.0 12.1 3.3 6.5 8.4 1.2 1 0 0 1 1 1 0 TAP42-like family Daxx PF03344.10 EGD96309.1 - 3.4 6.0 23.6 3.7 5.9 16.3 1.0 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EGD96309.1 - 6.9 5.8 21.2 6.4 5.9 14.7 1.0 1 0 0 1 1 1 0 SDA1 FA_desaturase PF00487.19 EGD96310.1 - 3.9e-18 65.8 25.4 3.9e-18 65.8 17.6 1.9 1 1 1 2 2 2 1 Fatty acid desaturase EI24 PF07264.6 EGD96310.1 - 0.00013 21.5 0.5 0.00013 21.5 0.4 1.7 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) GDPD PF03009.12 EGD96311.1 - 5.1e-18 65.5 0.0 6.9e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family adh_short PF00106.20 EGD96312.1 - 3.1e-13 49.9 0.0 5e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EGD96312.1 - 1.5e-05 24.7 0.0 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD96312.1 - 9.4e-05 21.9 0.0 0.33 10.3 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGD96312.1 - 0.00027 19.9 0.0 0.00092 18.2 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EGD96312.1 - 0.027 14.4 0.0 0.079 12.9 0.0 1.8 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGD96312.1 - 0.069 12.0 0.0 0.33 9.7 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EGD96313.1 - 8.6e-30 103.6 28.4 8.6e-30 103.6 19.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Prominin PF05478.6 EGD96313.1 - 0.049 11.1 0.2 0.072 10.6 0.1 1.2 1 0 0 1 1 1 0 Prominin PDGLE PF13190.1 EGD96313.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.7 3 0 0 3 3 3 0 PDGLE domain Methyltransf_26 PF13659.1 EGD96315.1 - 1.7e-11 44.1 0.0 2.1e-10 40.6 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD96315.1 - 5.8e-09 35.7 0.0 9.6e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD96315.1 - 7.6e-08 32.9 0.0 2.1e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD96315.1 - 2.9e-06 26.7 0.0 7.9e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGD96315.1 - 2.9e-05 24.3 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EGD96315.1 - 0.00026 20.1 0.0 0.00073 18.7 0.0 1.6 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_10 PF05971.7 EGD96315.1 - 0.00062 19.0 0.0 0.0016 17.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF890) PrmA PF06325.8 EGD96315.1 - 0.00099 18.3 0.0 0.0014 17.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EGD96315.1 - 0.0028 16.8 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AviRa PF11599.3 EGD96315.1 - 0.0049 15.9 0.1 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa UPF0020 PF01170.13 EGD96315.1 - 0.0058 16.2 0.0 0.12 11.9 0.0 2.4 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 EGD96315.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGD96315.1 - 0.095 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGD96315.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Asp PF00026.18 EGD96316.1 - 1.3e-66 225.0 0.1 1.7e-66 224.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGD96316.1 - 3.8e-09 36.7 0.3 9.7e-08 32.1 0.2 2.9 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGD96316.1 - 7.2e-06 26.4 1.3 0.0052 17.2 0.2 3.8 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 EGD96316.1 - 0.0024 17.4 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EGD96316.1 - 0.068 13.0 0.1 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SLX9 PF15341.1 EGD96317.1 - 0.037 14.4 0.7 0.054 13.9 0.5 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 zf-C2H2_4 PF13894.1 EGD96319.1 - 0.00068 19.7 3.8 0.0021 18.2 2.6 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD96319.1 - 0.0046 17.2 2.9 0.014 15.6 2.0 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD96319.1 - 0.0065 16.7 1.7 1 9.7 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain STAT_alpha PF01017.15 EGD96324.1 - 0.017 14.8 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF77 PF01910.12 EGD96326.1 - 1.6e-18 66.1 0.2 1.8e-18 65.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 TPR_8 PF13181.1 EGD96327.1 - 0.00029 20.4 0.2 0.25 11.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGD96327.1 - 0.0061 17.0 3.2 33 5.5 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGD96327.1 - 0.018 14.9 2.4 46 4.0 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGD96327.1 - 0.068 12.8 2.9 0.24 11.0 0.0 3.0 3 1 0 3 3 3 0 TPR repeat TPR_16 PF13432.1 EGD96327.1 - 0.069 13.8 5.0 21 5.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGD96327.1 - 0.22 11.1 2.6 5.5 6.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGD96327.1 - 0.27 11.2 6.3 2.9 8.0 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGD96327.1 - 0.5 10.2 2.8 15 5.6 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 EGD96327.1 - 1 9.2 6.7 8.2 6.3 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 EGD96327.1 - 1.4 9.6 6.7 3.5 8.4 0.9 3.4 2 1 0 2 2 2 0 Sel1 repeat TPR_19 PF14559.1 EGD96327.1 - 3.6 7.9 7.4 22 5.4 0.1 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat PH_10 PF15411.1 EGD96328.1 - 4.3e-12 46.2 0.0 5.3e-08 33.0 0.0 2.4 1 1 1 2 2 2 2 Pleckstrin homology domain VWA_3 PF13768.1 EGD96328.1 - 1.6e-08 34.3 0.0 1.3e-07 31.3 0.0 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EGD96328.1 - 4.1e-07 29.8 0.0 8.7e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EGD96328.1 - 1.7e-06 27.7 5.2 3.2e-06 26.8 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGD96328.1 - 9e-05 22.1 3.8 0.00015 21.4 2.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGD96328.1 - 0.00064 19.3 1.7 0.0011 18.5 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD96328.1 - 0.0037 17.2 4.8 0.0066 16.4 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD96328.1 - 0.017 15.2 1.7 0.033 14.2 1.2 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGD96328.1 - 0.023 14.3 4.4 0.041 13.5 3.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EGD96328.1 - 0.24 11.4 4.1 0.46 10.5 2.8 1.5 1 0 0 1 1 1 0 RING-like domain Ribosomal_L12 PF00542.14 EGD96329.1 - 3.9e-20 71.6 8.3 9.7e-19 67.1 3.9 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EGD96329.1 - 0.011 16.1 6.3 0.011 16.1 4.3 2.4 1 1 2 3 3 3 0 60s Acidic ribosomal protein DFP PF04127.10 EGD96329.1 - 0.043 13.4 0.4 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Cpn60_TCP1 PF00118.19 EGD96330.1 - 4.9e-131 437.6 2.0 5.7e-131 437.4 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nucleoplasmin PF03066.10 EGD96330.1 - 0.06 12.8 3.7 0.12 11.8 2.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin PORR PF11955.3 EGD96330.1 - 0.13 10.9 0.0 0.33 9.6 0.0 1.6 1 0 0 1 1 1 0 Plant organelle RNA recognition domain RXT2_N PF08595.6 EGD96330.1 - 0.58 9.9 3.7 1.7 8.4 2.6 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal E1_dh PF00676.15 EGD96331.1 - 3.3e-113 377.3 0.2 5e-113 376.7 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EGD96331.1 - 3.4e-05 22.9 0.0 5.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EGD96331.1 - 0.024 14.2 2.0 0.055 13.0 1.4 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain KRTAP7 PF15034.1 EGD96331.1 - 4.3 8.0 7.4 5.6 7.6 0.3 2.8 2 1 0 2 2 2 0 KRTAP type 7 family S4 PF01479.20 EGD96333.1 - 9.4e-16 56.9 0.0 2.3e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EGD96333.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 S4 domain PAP1 PF08601.5 EGD96333.1 - 0.08 12.6 10.9 1.5 8.4 6.0 2.1 2 0 0 2 2 2 0 Transcription factor PAP1 RasGAP PF00616.14 EGD96333.1 - 0.25 10.9 2.6 0.12 12.0 0.2 1.6 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase Dak2 PF02734.12 EGD96333.1 - 0.71 9.5 6.7 1.3 8.7 3.6 2.0 1 1 1 2 2 2 0 DAK2 domain NPV_P10 PF05531.7 EGD96333.1 - 0.91 9.8 3.5 2.5 8.4 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pex14_N PF04695.8 EGD96333.1 - 3 7.8 14.2 4.7 7.2 7.9 2.7 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Abhydrolase_6 PF12697.2 EGD96334.1 - 4.4e-32 111.8 0.7 5.6e-32 111.4 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD96334.1 - 1.4e-14 54.2 0.3 3.1e-13 49.8 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD96334.1 - 1.9e-14 53.6 0.0 2.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGD96334.1 - 2e-06 27.5 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 EGD96334.1 - 0.00033 20.1 0.1 0.0018 17.7 0.1 2.0 1 1 0 1 1 1 1 Putative esterase UPF0227 PF05728.7 EGD96334.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Thioesterase PF00975.15 EGD96334.1 - 0.019 15.1 0.0 0.031 14.4 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain Chlorophyllase PF07224.6 EGD96334.1 - 0.024 13.4 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_3 PF07859.8 EGD96334.1 - 0.059 12.9 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EGD96334.1 - 0.16 11.3 1.4 0.27 10.6 0.1 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region PAF-AH_p_II PF03403.8 EGD96334.1 - 0.19 9.9 0.2 2.9 6.0 0.0 2.0 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II APH PF01636.18 EGD96335.1 - 1.8e-07 31.1 1.9 1.9e-06 27.7 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family T2SK PF03934.8 EGD96335.1 - 0.089 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K AA_permease_2 PF13520.1 EGD96336.1 - 2.8e-65 220.5 42.9 3.8e-65 220.1 29.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD96336.1 - 2.3e-30 105.3 43.3 2.6e-30 105.2 21.4 2.3 1 1 1 2 2 2 2 Amino acid permease NAD_binding_1 PF00175.16 EGD96337.1 - 3.1e-06 27.6 0.0 0.00024 21.6 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGD96337.1 - 6e-06 26.3 0.0 1.6e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGD96337.1 - 0.054 13.4 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Aminotran_5 PF00266.14 EGD96338.1 - 1.2e-29 103.1 0.0 6.1e-19 68.0 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Aconitase PF00330.15 EGD96339.1 - 4.7e-71 239.6 0.5 1.1e-45 156.0 0.1 2.8 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGD96339.1 - 6.2e-23 81.3 0.0 1.4e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Peptidase_M22 PF00814.20 EGD96340.1 - 3.8e-84 282.3 0.0 4.6e-84 282.0 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Chrome_Resist PF09828.4 EGD96340.1 - 0.052 13.7 0.0 0.088 13.0 0.0 1.4 1 0 0 1 1 1 0 Chromate resistance exported protein SET PF00856.23 EGD96341.1 - 4.4e-16 59.6 0.0 8.7e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EGD96341.1 - 7.8e-07 29.0 1.4 1.6e-06 28.0 0.4 2.0 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding FAM178 PF14816.1 EGD96341.1 - 0.065 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 EPL1 PF10513.4 EGD96342.1 - 3.7e-31 108.5 5.0 1.6e-30 106.4 0.5 2.6 2 1 0 2 2 2 2 Enhancer of polycomb-like EF-hand_1 PF00036.27 EGD96343.1 - 8.1e-27 90.4 12.3 1.3e-07 30.4 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGD96343.1 - 2e-22 79.0 3.0 7.3e-12 45.2 0.4 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGD96343.1 - 1.4e-20 71.2 5.3 5e-05 22.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGD96343.1 - 2.2e-18 64.6 12.7 1.3e-06 27.4 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EGD96343.1 - 7.8e-15 54.2 14.5 1.1e-05 24.9 0.5 4.6 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGD96343.1 - 3.9e-06 26.8 0.0 0.0025 17.8 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EGD96343.1 - 4.4e-05 23.1 8.1 0.017 14.8 0.2 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EGD96343.1 - 0.013 15.3 0.1 0.48 10.3 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain Ribosomal_S9 PF00380.14 EGD96346.1 - 5.7e-35 120.1 0.6 9.5e-35 119.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 EGD96347.1 - 5.7e-48 161.0 0.2 9.2e-48 160.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EGD96347.1 - 4.4e-11 42.6 0.0 1.1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGD96347.1 - 1e-08 35.2 0.0 2.1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD96347.1 - 3.9e-08 33.3 0.0 1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD96347.1 - 9.9e-08 31.7 0.0 2.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD96347.1 - 3.1e-06 27.5 0.0 6.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGD96347.1 - 6e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2360 PF10152.4 EGD96347.1 - 0.029 14.6 0.1 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MCPVI PF02993.9 EGD96347.1 - 9.8 6.2 6.3 17 5.4 4.4 1.3 1 0 0 1 1 1 0 Minor capsid protein VI NIF PF03031.13 EGD96348.1 - 1.8e-24 86.2 2.0 4.6e-24 84.8 1.4 1.7 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Transposase_23 PF03017.9 EGD96348.1 - 0.022 14.2 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 TNP1/EN/SPM transposase DUF947 PF06102.7 EGD96349.1 - 1.9e-38 131.9 38.2 1.9e-38 131.9 26.4 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF947) DUF1509 PF07420.6 EGD96351.1 - 0.95 8.6 11.8 0.96 8.6 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) AMPKBI PF04739.10 EGD96354.1 - 4.3e-28 97.1 1.3 6.3e-28 96.6 0.1 2.0 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF4399 PF14347.1 EGD96354.1 - 0.018 15.0 0.2 0.17 11.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) Mannosyl_trans3 PF11051.3 EGD96356.1 - 1.2e-72 244.5 0.0 4.3e-72 242.7 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EGD96356.1 - 0.018 14.3 0.1 0.05 12.9 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 8 ABC1 PF03109.11 EGD96357.1 - 1.2e-33 115.6 0.0 3.1e-33 114.2 0.0 1.8 1 0 0 1 1 1 1 ABC1 family UreF PF01730.11 EGD96358.1 - 1.8e-13 50.8 4.3 3.5e-13 49.9 3.0 1.5 1 1 0 1 1 1 1 UreF BRE1 PF08647.6 EGD96359.1 - 3e-24 84.8 13.4 3e-24 84.8 9.3 6.4 5 1 0 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EGD96359.1 - 1.4e-09 37.8 10.7 2.4e-09 37.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD96359.1 - 6.9e-09 35.2 8.4 1.2e-08 34.4 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD96359.1 - 8e-08 31.8 10.8 1.5e-07 30.9 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD96359.1 - 2.3e-07 30.5 8.3 4.5e-07 29.5 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGD96359.1 - 2.7e-06 26.9 11.4 5.1e-06 26.1 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGD96359.1 - 1.1e-05 25.0 6.5 3.5e-05 23.4 4.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger Reo_sigmaC PF04582.7 EGD96359.1 - 6.2e-05 22.3 41.1 0.0033 16.6 1.1 4.6 2 1 3 5 5 5 3 Reovirus sigma C capsid protein zf-C3HC4_4 PF15227.1 EGD96359.1 - 0.0018 18.1 7.2 0.0034 17.2 5.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGD96359.1 - 0.0023 18.0 2.6 0.0063 16.5 1.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger DUF745 PF05335.8 EGD96359.1 - 0.0065 16.0 5.0 0.0065 16.0 3.5 5.6 3 2 3 6 6 4 1 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.4 EGD96359.1 - 0.012 15.4 9.1 0.012 15.4 6.3 6.3 2 2 4 6 6 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-RING_4 PF14570.1 EGD96359.1 - 0.032 13.8 7.6 0.17 11.4 5.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EGD96359.1 - 0.037 13.5 3.9 0.08 12.4 2.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 EGD96359.1 - 0.052 13.3 6.5 0.11 12.3 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Nse PF11789.3 EGD96359.1 - 0.12 11.8 6.1 0.32 10.5 4.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EGD96359.1 - 0.14 11.9 4.1 0.27 11.0 2.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.21 EGD96359.1 - 0.27 11.6 3.8 1.5 9.3 0.2 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type FYVE PF01363.16 EGD96359.1 - 1.3 9.0 12.6 21 5.0 8.2 2.5 1 1 1 2 2 2 0 FYVE zinc finger IncA PF04156.9 EGD96359.1 - 4.1 6.9 86.3 0.52 9.8 1.4 5.6 1 1 3 5 5 4 0 IncA protein Myosin_tail_1 PF01576.14 EGD96359.1 - 6.7 4.2 82.6 0.6 7.7 0.0 3.8 2 1 2 4 4 4 0 Myosin tail HALZ PF02183.13 EGD96359.1 - 10 5.9 31.1 1.8 8.3 0.2 6.5 6 0 0 6 6 5 0 Homeobox associated leucine zipper Myb_DNA-binding PF00249.26 EGD96360.1 - 8.4e-05 22.5 0.0 0.0013 18.7 0.0 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain FTZ PF03867.9 EGD96360.1 - 0.87 8.7 6.7 2.4 7.3 2.4 2.3 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region DUF1183 PF06682.7 EGD96361.1 - 6.8e-79 265.7 10.8 1.6e-78 264.5 7.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) DUF2404 PF10296.4 EGD96362.1 - 9e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ARD PF03079.9 EGD96363.1 - 2.9e-48 163.7 0.2 3.4e-48 163.5 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EGD96363.1 - 4.4e-09 35.6 0.1 7.1e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EGD96363.1 - 3.2e-05 23.6 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EGD96363.1 - 0.0049 16.3 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Cupin GIDA PF01134.17 EGD96364.1 - 4.5e-155 516.3 0.0 1.1e-154 515.1 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EGD96364.1 - 1.6e-16 60.1 0.0 4e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EGD96364.1 - 1.7e-08 34.6 0.3 3.2e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD96364.1 - 3e-06 26.5 0.4 4.4e-06 26.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EGD96364.1 - 2.5e-05 23.3 2.1 0.027 13.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD96364.1 - 0.0004 19.3 1.6 0.00079 18.3 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EGD96364.1 - 0.023 13.3 0.1 3.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 EGD96364.1 - 0.026 12.9 0.6 0.29 9.5 0.2 2.3 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EGD96364.1 - 0.035 13.6 0.2 0.07 12.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 EGD96364.1 - 0.12 12.4 0.0 0.5 10.3 0.0 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF3605 PF12239.3 EGD96365.1 - 1.2e-43 148.7 2.8 1.9e-43 148.0 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Sec1 PF00995.18 EGD96366.1 - 1.3e-152 509.3 0.0 1.5e-152 509.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family adh_short PF00106.20 EGD96367.1 - 2.2e-22 79.7 0.0 3.1e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD96367.1 - 7.4e-12 45.2 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD96367.1 - 1.3e-06 27.9 0.0 2.7e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGD96367.1 - 0.0002 21.4 0.0 0.0004 20.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGD96367.1 - 0.0005 19.0 0.0 0.00063 18.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGD96367.1 - 0.00053 18.9 0.0 0.00085 18.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EGD96367.1 - 0.0047 16.2 0.0 0.011 15.0 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EGD96367.1 - 0.006 15.3 0.0 0.0083 14.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Synaptonemal_3 PF15191.1 EGD96367.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 NAD_binding_8 PF13450.1 EGD96368.1 - 1.1e-13 50.9 0.2 2.2e-12 46.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD96368.1 - 1.3e-08 34.1 0.0 3.1e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGD96368.1 - 5.5e-08 32.9 0.1 0.0009 19.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGD96368.1 - 2.8e-06 26.4 0.2 5.1e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EGD96368.1 - 7.7e-06 25.2 0.0 0.002 17.2 0.0 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EGD96368.1 - 1.7e-05 23.5 0.5 0.00015 20.4 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EGD96368.1 - 3.8e-05 23.8 0.4 0.00065 19.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD96368.1 - 4.5e-05 22.6 0.0 8.9e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EGD96368.1 - 5.4e-05 23.5 0.2 0.13 12.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD96368.1 - 0.00052 19.2 0.3 0.0034 16.5 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGD96368.1 - 0.0018 17.0 0.1 0.0058 15.3 0.0 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EGD96368.1 - 0.0028 16.6 0.1 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EGD96368.1 - 0.0054 16.5 0.3 0.042 13.6 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EGD96368.1 - 0.025 13.6 0.2 0.073 12.1 0.1 1.8 2 1 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EGD96368.1 - 0.058 12.2 0.2 0.098 11.4 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 EGD96368.1 - 0.084 12.3 0.0 0.53 9.7 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.14 EGD96368.1 - 0.099 11.7 0.0 9.2 5.3 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Malic_M PF03949.10 EGD96368.1 - 0.19 11.2 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Tyr-DNA_phospho PF06087.7 EGD96369.1 - 9.4e-80 268.3 0.0 1.2e-79 268.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EGD96369.1 - 2.7e-06 27.1 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain Daxx PF03344.10 EGD96369.1 - 0.034 12.6 6.5 0.052 12.0 4.5 1.2 1 0 0 1 1 1 0 Daxx Family PTN_MK_N PF05196.8 EGD96369.1 - 0.5 10.3 3.4 7.1 6.6 0.1 2.8 3 0 0 3 3 3 0 PTN/MK heparin-binding protein family, N-terminal domain Ribosomal_60s PF00428.14 EGD96369.1 - 1.3 9.4 25.6 0.045 14.1 6.6 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein NOA36 PF06524.7 EGD96369.1 - 3.4 6.8 5.4 6 6.0 3.8 1.3 1 0 0 1 1 1 0 NOA36 protein 2-Hacid_dh_C PF02826.14 EGD96370.1 - 5.9e-55 185.1 0.0 7.7e-55 184.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD96370.1 - 4.9e-19 68.1 0.0 6.8e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGD96370.1 - 5.3e-08 32.8 0.1 9.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGD96370.1 - 0.00083 19.7 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.16 EGD96370.1 - 0.016 14.7 0.0 0.052 13.1 0.0 1.7 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EGD96370.1 - 0.039 13.4 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EGD96370.1 - 0.072 12.8 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.1 EGD96370.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain CFEM PF05730.6 EGD96371.1 - 9.2e-12 44.6 11.3 1.6e-11 43.8 7.8 1.3 1 0 0 1 1 1 1 CFEM domain YEATS PF03366.11 EGD96372.1 - 1.1e-05 25.0 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 YEATS family Ran_BP1 PF00638.13 EGD96373.1 - 4.6e-52 175.2 2.0 7.5e-52 174.5 1.4 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EGD96373.1 - 0.001 18.7 0.4 0.0064 16.1 0.3 2.0 1 1 0 1 1 1 1 WH1 domain eIF-3c_N PF05470.7 EGD96373.1 - 5.6 4.9 11.8 7.3 4.5 8.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC27 PF09507.5 EGD96373.1 - 6.4 5.8 23.6 8 5.5 16.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ATP-synt_B PF00430.13 EGD96374.1 - 0.028 14.2 4.5 0.06 13.1 3.1 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF883 PF05957.8 EGD96374.1 - 0.29 11.5 6.2 0.25 11.7 3.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EGD96374.1 - 0.96 8.9 7.8 5.4 6.4 5.4 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4096 PF13340.1 EGD96375.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) DUF3761 PF12587.3 EGD96375.1 - 7.3 6.7 11.9 14 5.8 0.1 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3761) Glyco_transf_15 PF01793.11 EGD96376.1 - 8.1e-132 439.1 6.1 1e-131 438.8 4.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PH PF00169.24 EGD96377.1 - 4.7e-26 91.0 1.9 1.5e-13 50.8 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 EGD96377.1 - 1.3e-12 47.9 4.1 2.4e-07 30.9 0.1 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 EGD96377.1 - 2.1e-10 40.8 4.3 0.00019 21.6 0.1 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.1 EGD96377.1 - 0.0008 19.4 0.0 0.015 15.3 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain UIM PF02809.15 EGD96377.1 - 0.029 13.9 1.8 0.06 12.9 1.3 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif DOT1 PF08123.8 EGD96378.1 - 1.1e-76 256.7 0.0 1.6e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EGD96378.1 - 3.7e-06 26.9 0.1 1.2e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD96378.1 - 0.001 18.6 0.0 0.0021 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD96378.1 - 0.0011 19.5 0.1 0.0023 18.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain NmrA PF05368.8 EGD96378.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family ATG16 PF08614.6 EGD96379.1 - 6.1e-44 150.1 17.6 7.2e-44 149.9 12.2 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.1 EGD96379.1 - 0.0021 17.0 9.8 0.0021 17.0 6.8 1.5 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region GvpG PF05120.7 EGD96379.1 - 0.035 13.9 2.0 0.035 13.9 1.4 2.0 1 1 0 1 1 1 0 Gas vesicle protein G Sec2p PF06428.6 EGD96379.1 - 0.069 13.0 12.0 0.18 11.6 8.3 1.7 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p SecD-TM1 PF13721.1 EGD96379.1 - 0.25 11.6 2.2 0.43 10.8 1.0 1.8 1 1 0 1 1 1 0 SecD export protein N-terminal TM region KIAA1430 PF13879.1 EGD96379.1 - 0.25 11.7 4.6 0.31 11.4 0.1 2.1 1 1 1 2 2 2 0 KIAA1430 homologue IncA PF04156.9 EGD96379.1 - 0.34 10.4 16.8 0.55 9.7 10.8 1.8 1 1 1 2 2 2 0 IncA protein DUF4201 PF13870.1 EGD96379.1 - 0.53 9.7 10.7 0.99 8.8 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Mnd1 PF03962.10 EGD96379.1 - 0.6 9.7 13.1 0.89 9.1 9.1 1.4 1 1 0 1 1 1 0 Mnd1 family V_ATPase_I PF01496.14 EGD96379.1 - 0.78 7.5 3.8 0.82 7.4 2.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup54 PF13874.1 EGD96379.1 - 1.7 8.2 12.4 0.93 9.1 1.9 2.5 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Laminin_II PF06009.7 EGD96379.1 - 2.6 7.8 7.9 6.2 6.5 0.7 2.3 1 1 1 2 2 2 0 Laminin Domain II MscS_porin PF12795.2 EGD96379.1 - 4.5 6.5 20.8 1.2 8.3 10.2 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain GAS PF13851.1 EGD96379.1 - 5.1 6.2 16.8 2.7 7.1 8.3 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF883 PF05957.8 EGD96379.1 - 6.9 7.1 12.3 0.3 11.5 0.8 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Ras PF00071.17 EGD96380.1 - 6.7e-56 188.1 0.2 8.1e-56 187.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD96380.1 - 4e-20 72.4 0.0 7e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD96380.1 - 8.5e-14 51.1 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGD96380.1 - 4.2e-08 32.6 0.1 5.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGD96380.1 - 9.4e-08 31.7 0.0 2.1e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGD96380.1 - 2.8e-07 30.5 0.0 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGD96380.1 - 0.00037 20.6 0.0 0.00066 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGD96380.1 - 0.00082 18.5 0.1 0.0017 17.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EGD96380.1 - 0.003 17.0 0.0 0.07 12.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EGD96380.1 - 0.0036 17.0 0.5 0.0098 15.6 0.1 1.8 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 EGD96380.1 - 0.0051 16.2 0.0 0.022 14.2 0.0 1.8 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EGD96380.1 - 0.0054 16.4 0.1 0.015 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EGD96380.1 - 0.0059 16.2 0.2 0.01 15.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EGD96380.1 - 0.0059 16.3 0.0 0.0096 15.6 0.0 1.4 1 0 0 1 1 1 1 NTPase Septin PF00735.13 EGD96380.1 - 0.0079 15.2 0.3 0.032 13.2 0.0 2.1 3 0 0 3 3 3 1 Septin ATP_bind_1 PF03029.12 EGD96380.1 - 0.0087 15.6 0.3 0.31 10.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.5 EGD96380.1 - 0.0099 15.1 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EGD96380.1 - 0.011 15.2 0.2 0.027 13.9 0.1 1.6 1 1 1 2 2 2 0 AAA-like domain MobB PF03205.9 EGD96380.1 - 0.015 15.0 0.1 0.033 13.8 0.1 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGD96380.1 - 0.018 14.9 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EGD96380.1 - 0.075 12.9 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EGD96380.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EGD96380.1 - 0.15 12.3 0.1 0.33 11.2 0.0 1.6 2 0 0 2 2 2 0 ABC transporter EamA PF00892.15 EGD96381.1 - 1.7e-09 37.7 31.4 6.8e-08 32.5 3.6 2.9 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EGD96381.1 - 2.3e-07 29.9 10.2 2.3e-07 29.9 7.0 1.9 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EGD96381.1 - 1.7e-06 27.2 12.6 5.2e-06 25.5 7.7 1.9 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.11 EGD96381.1 - 5.8e-05 22.7 30.3 0.00028 20.5 6.5 2.9 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 EGD96381.1 - 0.0004 20.5 2.8 0.0004 20.5 2.0 3.1 3 1 0 3 3 3 2 Multidrug resistance efflux transporter Spb1_C PF07780.7 EGD96382.1 - 5.7e-76 254.7 17.9 5.7e-76 254.7 12.4 3.4 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EGD96382.1 - 5.3e-56 188.5 9.2 5.3e-56 188.5 6.4 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EGD96382.1 - 7.4e-54 182.4 0.0 1.5e-53 181.4 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Zn_clus PF00172.13 EGD96384.1 - 3.4e-07 30.0 10.5 6.7e-07 29.1 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGD96384.1 - 0.00015 20.7 0.0 0.00027 19.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BiPBP_C PF06832.7 EGD96385.1 - 0.05 13.5 0.3 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family EF-hand_4 PF12763.2 EGD96386.1 - 0.00071 19.2 0.1 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.20 EGD96387.1 - 3.8e-70 235.9 0.0 4.8e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96387.1 - 1e-32 113.2 0.0 1.4e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGD96387.1 - 1.2e-08 35.3 2.8 3e-08 34.0 1.9 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGD96387.1 - 0.0043 16.0 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DNA_ligase_A_M PF01068.16 EGD96388.1 - 1.2e-47 161.8 0.1 4.9e-47 159.9 0.0 2.1 3 0 0 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGD96388.1 - 6.1e-36 123.8 0.0 1.5e-35 122.6 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGD96388.1 - 3.9e-17 62.4 0.0 1e-16 61.1 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EGD96388.1 - 1.6e-10 40.9 0.2 6.4e-07 29.4 0.1 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGD96388.1 - 0.031 14.1 0.0 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 twin BRCT domain mRNA_cap_enzyme PF01331.14 EGD96388.1 - 0.039 13.6 0.0 0.78 9.4 0.0 2.8 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain Fungal_trans PF04082.13 EGD96389.1 - 1.3e-44 152.0 0.1 2.3e-44 151.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD96389.1 - 3.8e-08 33.1 9.1 7.4e-08 32.1 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 EGD96389.1 - 0.019 14.6 4.2 0.047 13.3 2.9 1.7 1 0 0 1 1 1 0 PHD-finger Metallophos PF00149.23 EGD96390.1 - 8.3e-36 123.2 0.5 6.7e-29 100.7 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF4646 PF15496.1 EGD96392.1 - 5.6e-08 32.8 0.0 8.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) ALG3 PF05208.8 EGD96393.1 - 9.5e-128 426.5 22.9 1.1e-127 426.3 15.8 1.0 1 0 0 1 1 1 1 ALG3 protein CRPA PF05745.6 EGD96393.1 - 0.38 10.5 2.6 5.6 6.7 0.2 3.1 2 1 1 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) eIF-1a PF01176.14 EGD96394.1 - 4.8e-19 67.5 0.0 7.6e-19 66.9 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pkinase PF00069.20 EGD96395.1 - 2.8e-63 213.5 0.0 6e-63 212.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96395.1 - 1.5e-35 122.5 0.0 2.7e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EGD96395.1 - 1.4e-33 114.3 12.8 7.1e-19 67.3 3.2 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EGD96395.1 - 7.8e-21 73.5 27.6 1.9e-11 43.5 6.3 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EGD96395.1 - 2.9e-14 53.3 2.2 9.4e-14 51.6 1.5 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGD96395.1 - 0.019 13.9 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like C2 PF00168.25 EGD96395.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 C2 domain Uds1 PF15456.1 EGD96395.1 - 3 7.8 5.9 0.68 9.9 0.7 2.3 2 0 0 2 2 2 0 Up-regulated During Septation PHD_2 PF13831.1 EGD96395.1 - 4.3 6.7 15.4 7.3 5.9 2.0 2.6 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 EGD96395.1 - 7.7 6.4 19.2 2.1 8.2 3.6 2.6 1 1 1 2 2 2 0 FYVE-type zinc finger TFCD_C PF12612.3 EGD96397.1 - 2.8e-36 124.7 0.2 1.2e-35 122.7 0.1 2.1 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EGD96397.1 - 2.6e-05 23.9 0.3 2 8.6 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EGD96397.1 - 0.0018 18.5 3.3 1.2 9.4 0.2 4.3 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EGD96397.1 - 0.0069 16.8 5.0 1.7 9.2 0.0 4.6 4 0 0 4 4 4 2 HEAT-like repeat RRM_1 PF00076.17 EGD96398.1 - 4.1e-26 90.4 3.3 3e-12 45.9 0.2 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD96398.1 - 2.6e-16 59.3 0.1 1e-06 28.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD96398.1 - 3.7e-15 55.4 0.0 2.8e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-synt_D PF01813.12 EGD96399.1 - 7.1e-65 218.2 1.4 9.5e-65 217.8 1.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.1 EGD96399.1 - 0.026 14.4 2.1 0.026 14.4 1.4 1.9 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Viral_P18 PF04521.8 EGD96399.1 - 1.6 8.1 4.8 18 4.8 0.1 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TPR_14 PF13428.1 EGD96400.1 - 5.6e-12 45.1 11.2 2.9 8.7 0.0 10.7 11 2 2 13 13 12 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD96400.1 - 1.6e-11 43.9 0.2 1.4 8.9 0.0 7.8 7 1 1 8 8 7 1 Tetratricopeptide repeat Suf PF05843.9 EGD96400.1 - 4.9e-10 39.6 9.8 0.0078 15.9 0.2 5.6 3 1 2 5 5 5 4 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EGD96400.1 - 1.8e-09 37.7 0.0 0.092 13.0 0.0 6.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGD96400.1 - 2.4e-07 30.1 4.5 0.00093 18.3 0.5 4.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD96400.1 - 5.2e-07 29.2 1.5 7.7 6.2 0.0 7.0 8 1 1 9 9 8 2 TPR repeat TPR_2 PF07719.12 EGD96400.1 - 8.3e-06 25.3 12.8 1.1 9.3 0.0 7.4 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGD96400.1 - 1.6e-05 24.3 3.8 0.78 9.6 0.0 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EGD96400.1 - 2e-05 24.3 8.1 2.9 7.7 0.1 6.8 6 2 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_17 PF13431.1 EGD96400.1 - 0.00062 19.7 4.2 1.2 9.5 0.0 6.3 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD96400.1 - 0.00063 19.3 4.9 11 6.1 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGD96400.1 - 0.0019 17.7 0.0 3.6 7.3 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat HAT PF02184.11 EGD96400.1 - 0.0032 17.1 3.0 1.7 8.4 0.1 5.4 5 0 0 5 5 4 1 HAT (Half-A-TPR) repeat NRDE-2 PF08424.5 EGD96400.1 - 0.015 14.2 9.7 0.024 13.5 1.1 4.9 3 2 1 4 4 4 0 NRDE-2, necessary for RNA interference DUF1470 PF07336.6 EGD96400.1 - 0.073 13.3 3.1 3.5 7.9 2.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1470) TPR_6 PF13174.1 EGD96400.1 - 1.7 9.2 9.3 24 5.6 0.0 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat Sec7 PF01369.15 EGD96401.1 - 1.3e-57 194.5 0.0 2.3e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EGD96401.1 - 7.3e-22 77.5 1.3 9.2e-15 54.4 0.1 3.4 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal RhoGEF PF00621.15 EGD96403.1 - 3.5e-21 75.8 0.0 7.1e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 EGD96403.1 - 3.8e-05 23.2 0.0 7.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DivIVA PF05103.8 EGD96403.1 - 0.76 9.8 5.2 2.7 8.0 3.6 2.0 1 0 0 1 1 1 0 DivIVA protein Myosin_tail_1 PF01576.14 EGD96403.1 - 1 7.0 12.8 0.41 8.2 6.5 1.7 1 1 1 2 2 2 0 Myosin tail ATP_bind_3 PF01171.15 EGD96404.1 - 4.8e-42 143.5 0.0 1.8e-40 138.3 0.0 2.4 1 1 0 1 1 1 1 PP-loop family NAD_synthase PF02540.12 EGD96404.1 - 0.0091 14.9 0.0 0.069 12.0 0.0 2.2 2 0 0 2 2 2 1 NAD synthase Mito_carr PF00153.22 EGD96405.1 - 4e-46 154.6 1.7 4.4e-18 64.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.3 EGD96406.1 - 8.7e-92 308.0 0.0 2.7e-87 293.2 0.3 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EGD96406.1 - 4.5e-28 96.0 17.8 4e-07 29.6 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Pkinase PF00069.20 EGD96407.1 - 5.3e-58 196.1 0.0 1e-57 195.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96407.1 - 2.6e-21 75.8 0.0 4.1e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD96407.1 - 0.0024 16.9 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD96407.1 - 0.0039 16.9 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD96407.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L11 PF00298.14 EGD96408.1 - 1.1e-22 79.9 0.1 1.8e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EGD96408.1 - 6.7e-14 51.0 0.3 2.2e-13 49.4 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Svf1 PF08622.5 EGD96409.1 - 3.4e-123 410.7 0.0 4.3e-123 410.4 0.0 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EGD96409.1 - 0.022 14.0 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) DUF3853 PF12964.2 EGD96410.1 - 0.0048 16.6 0.3 0.0061 16.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3853) Histone PF00125.19 EGD96410.1 - 0.12 12.5 1.2 0.23 11.6 0.8 1.6 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Dynein_heavy PF03028.10 EGD96412.1 - 3.5e-85 286.5 1.6 4e-85 286.2 0.0 1.9 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EGD96412.1 - 1.4e-49 168.6 0.0 4.7e-49 166.9 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EGD96412.1 - 2.9e-44 150.6 0.1 2.6e-43 147.4 0.1 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EGD96412.1 - 5.5e-42 143.5 2.4 5e-41 140.4 0.2 2.9 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 EGD96412.1 - 8e-40 136.6 7.0 1.2e-39 136.0 4.9 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EGD96412.1 - 4.9e-34 117.0 0.0 4.3e-11 42.7 0.0 5.8 5 0 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EGD96412.1 - 1e-19 70.6 0.0 8.6e-19 67.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA PF00004.24 EGD96412.1 - 1.4e-12 47.9 0.0 0.00017 21.7 0.0 3.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD96412.1 - 1.9e-12 47.4 2.0 0.0047 17.0 0.0 5.5 6 0 0 6 6 4 3 AAA domain AAA_33 PF13671.1 EGD96412.1 - 4.5e-10 39.5 0.5 0.12 12.1 0.0 4.3 4 0 0 4 4 3 3 AAA domain AAA_16 PF13191.1 EGD96412.1 - 7.8e-08 32.5 4.7 0.075 13.0 0.0 6.3 4 1 0 5 5 5 1 AAA ATPase domain AAA_17 PF13207.1 EGD96412.1 - 3.1e-07 31.2 3.1 0.021 15.6 0.0 4.7 5 0 0 5 5 3 1 AAA domain AAA_18 PF13238.1 EGD96412.1 - 6.5e-07 29.7 8.3 0.025 14.8 0.0 5.1 6 0 0 6 6 3 2 AAA domain AAA_14 PF13173.1 EGD96412.1 - 1.3e-06 28.3 0.0 0.1 12.4 0.0 4.6 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 EGD96412.1 - 3.5e-06 26.1 0.0 0.04 12.8 0.0 3.0 3 0 0 3 3 3 2 Type II/IV secretion system protein ABC_tran PF00005.22 EGD96412.1 - 6e-06 26.5 0.5 1 9.6 0.0 4.7 4 0 0 4 4 3 2 ABC transporter Mg_chelatase PF01078.16 EGD96412.1 - 6.9e-06 25.3 1.0 0.26 10.4 0.0 3.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 EGD96412.1 - 1.9e-05 24.1 0.0 1.1 8.8 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EGD96412.1 - 0.0002 21.0 0.0 0.46 10.2 0.0 3.4 3 0 0 3 3 3 1 Part of AAA domain Zeta_toxin PF06414.7 EGD96412.1 - 0.00031 19.8 5.8 0.49 9.4 0.0 4.4 5 0 0 5 5 4 2 Zeta toxin DUF258 PF03193.11 EGD96412.1 - 0.00046 19.4 0.0 3.9 6.6 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EGD96412.1 - 0.00056 19.4 0.4 11 5.3 0.0 3.8 4 0 0 4 4 4 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EGD96412.1 - 0.00074 18.9 0.0 0.16 11.3 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.1 EGD96412.1 - 0.0011 18.4 0.0 0.23 10.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain 3-alpha PF03475.9 EGD96412.1 - 0.0045 16.6 0.2 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 3-alpha domain PduV-EutP PF10662.4 EGD96412.1 - 0.021 14.3 1.6 3.7 7.0 0.1 4.1 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EGD96412.1 - 0.024 14.7 0.1 14 5.9 0.0 3.7 3 0 0 3 3 3 0 RNA helicase ERM PF00769.14 EGD96412.1 - 0.031 13.8 25.9 0.84 9.1 0.6 2.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family MobB PF03205.9 EGD96412.1 - 0.037 13.7 0.4 6.2 6.5 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EGD96412.1 - 0.057 13.0 2.1 15 5.1 0.0 3.9 3 0 0 3 3 3 0 NACHT domain V_ATPase_I PF01496.14 EGD96412.1 - 0.99 7.1 14.8 2.5 5.8 10.3 1.7 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DHC_N1 PF08385.7 EGD96413.1 - 1.5e-177 591.5 8.1 1.5e-177 591.5 5.6 3.3 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EGD96413.1 - 3.3e-129 430.9 2.4 3.3e-129 430.9 1.7 3.6 4 0 0 4 4 4 2 Dynein heavy chain, N-terminal region 2 Ribonuclease_3 PF00636.21 EGD96414.1 - 1.9e-40 137.8 0.0 7.1e-20 71.5 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGD96414.1 - 1.5e-24 86.3 0.0 4e-13 49.4 0.0 3.5 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EGD96414.1 - 8.9e-22 76.6 0.2 8.4e-19 67.1 0.1 3.3 3 0 0 3 3 3 2 Dicer dimerisation domain ResIII PF04851.10 EGD96414.1 - 2.5e-14 53.5 0.3 5.3e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGD96414.1 - 7.3e-13 48.1 0.0 2e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD96414.1 - 2.6e-10 40.0 0.0 6.3e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 EGD96414.1 - 0.0055 17.2 0.1 0.64 10.6 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif DUF2075 PF09848.4 EGD96414.1 - 0.029 13.3 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TAP42 PF04177.7 EGD96415.1 - 7.1e-46 156.7 12.1 2.7e-45 154.8 5.5 2.0 1 1 1 2 2 2 2 TAP42-like family PilJ PF13675.1 EGD96415.1 - 4.7 7.5 8.2 1.7 8.9 0.5 2.9 1 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Lipase_GDSL_2 PF13472.1 EGD96416.1 - 2e-16 60.6 0.0 1e-15 58.3 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGD96416.1 - 5.7e-14 52.5 0.0 7.9e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PRP21_like_P PF12230.3 EGD96416.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Porphobil_deam PF01379.15 EGD96417.1 - 2.1e-78 262.1 0.0 2.7e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EGD96417.1 - 4.5e-18 65.1 0.5 8.4e-18 64.2 0.4 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF1534 PF07551.6 EGD96417.1 - 0.14 11.7 0.1 1.6 8.3 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1534) Lon_C PF05362.8 EGD96418.1 - 2.2e-69 232.8 0.2 4.5e-69 231.8 0.2 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EGD96418.1 - 3.3e-24 85.5 0.0 2.5e-23 82.7 0.0 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 EGD96418.1 - 1.4e-21 77.1 0.9 3.1e-21 75.9 0.0 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 EGD96418.1 - 4.6e-08 32.6 0.0 1.3e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EGD96418.1 - 6.7e-08 32.3 0.0 2.5e-07 30.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGD96418.1 - 3.8e-06 27.0 0.3 1.9e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EGD96418.1 - 5.8e-06 25.2 0.1 3e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 EGD96418.1 - 1.2e-05 24.8 0.0 3.2e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 EGD96418.1 - 2.3e-05 24.0 0.0 6.6e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGD96418.1 - 3e-05 24.8 0.0 0.00012 22.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGD96418.1 - 0.00012 21.7 0.1 0.00038 20.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EGD96418.1 - 0.00033 19.7 0.1 0.0013 17.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EGD96418.1 - 0.00041 20.3 0.0 0.0025 17.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGD96418.1 - 0.00043 20.4 0.1 0.0046 17.1 0.0 2.8 2 1 1 3 3 2 1 AAA domain Birna_VP4 PF01768.11 EGD96418.1 - 0.00073 18.6 0.0 0.0014 17.7 0.0 1.5 1 0 0 1 1 1 1 Birnavirus VP4 protein AAA_14 PF13173.1 EGD96418.1 - 0.00076 19.3 0.0 0.0034 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGD96418.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD96418.1 - 0.0026 16.8 0.0 0.0053 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EGD96418.1 - 0.0041 16.5 0.0 0.0099 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGD96418.1 - 0.01 16.0 0.0 0.045 13.9 0.0 2.2 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 EGD96418.1 - 0.014 14.9 0.0 0.043 13.4 0.0 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EGD96418.1 - 0.018 14.2 0.2 0.046 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EGD96418.1 - 0.021 14.5 0.0 0.067 12.8 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 EGD96418.1 - 0.024 14.2 0.2 0.059 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGD96418.1 - 0.027 14.7 1.0 0.058 13.7 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 EGD96418.1 - 0.031 13.7 0.7 0.71 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain PhoH PF02562.11 EGD96418.1 - 0.031 13.5 0.0 0.076 12.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 EGD96418.1 - 0.033 14.5 0.1 0.033 14.5 0.1 3.2 2 1 1 3 3 1 0 AAA domain NB-ARC PF00931.17 EGD96418.1 - 0.054 12.3 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_PrkA PF08298.6 EGD96418.1 - 0.055 12.1 0.1 0.15 10.7 0.0 1.6 1 1 0 1 1 1 0 PrkA AAA domain MobB PF03205.9 EGD96418.1 - 0.059 13.0 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activ_2 PF14532.1 EGD96418.1 - 0.068 13.2 0.1 0.37 10.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EGD96418.1 - 0.069 12.8 0.7 0.94 9.1 0.0 3.1 3 1 1 4 4 3 0 Archaeal ATPase AAA_11 PF13086.1 EGD96418.1 - 0.079 12.5 3.1 0.1 12.1 0.0 2.3 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGD96418.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.7 1 1 0 2 2 2 0 ABC transporter Striatin PF08232.7 EGD96418.1 - 6.2 7.1 8.1 2.2 8.5 0.2 2.3 2 0 0 2 2 2 0 Striatin family Ribosomal_L23 PF00276.15 EGD96419.1 - 1.7e-15 56.7 0.0 3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 RIO1 PF01163.17 EGD96420.1 - 9.7e-41 139.1 0.3 4.5e-28 97.8 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 EGD96420.1 - 2.2e-31 107.7 0.0 4.8e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EGD96420.1 - 2e-05 24.4 0.0 0.044 13.4 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGD96420.1 - 3.7e-05 22.8 0.0 0.001 18.1 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Chs3p PF12271.3 EGD96421.1 - 4e-139 462.5 14.9 4.6e-139 462.4 10.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Ribosomal_L18e PF00828.14 EGD96422.1 - 1.5e-17 64.2 0.1 2.7e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Pkinase PF00069.20 EGD96424.1 - 2.4e-48 164.5 0.0 3.5e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96424.1 - 9.1e-27 93.7 0.0 7e-26 90.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Zip PF02535.17 EGD96424.1 - 0.014 14.3 8.0 0.022 13.7 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EGD96424.1 - 1.2 8.4 16.6 2.1 7.6 11.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.4 EGD96424.1 - 7.8 4.6 5.6 11 4.1 3.9 1.2 1 0 0 1 1 1 0 Transmembrane protein CDC73 PF05179.9 EGD96425.1 - 0.038 13.3 8.9 0.046 13.0 6.2 1.0 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family DUF2215 PF10225.4 EGD96425.1 - 0.38 10.1 9.2 0.45 9.9 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Nucleo_P87 PF07267.6 EGD96425.1 - 0.93 8.0 13.0 1 7.9 9.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CRT10 PF08728.5 EGD96425.1 - 1.2 7.0 6.0 1.4 6.8 4.2 1.0 1 0 0 1 1 1 0 CRT10 SH3_1 PF00018.23 EGD96426.1 - 9.2e-06 24.9 0.0 1.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD96426.1 - 0.0011 18.4 0.0 0.0031 17.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain RCC1_2 PF13540.1 EGD96427.1 - 6.6e-12 44.7 3.8 4.5e-06 26.1 0.0 4.3 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EGD96427.1 - 4.1e-08 32.8 0.4 1.4e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGD96427.1 - 0.042 13.5 0.1 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 F-box domain DUF3688 PF12461.3 EGD96427.1 - 0.048 14.0 2.6 0.11 12.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3688) RCC1 PF00415.13 EGD96427.1 - 0.12 12.6 2.4 1.2 9.4 0.0 3.7 5 0 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat PQ-loop PF04193.9 EGD96429.1 - 6.9e-36 121.6 16.8 1e-18 66.5 1.3 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EGD96429.1 - 0.0013 18.5 7.6 0.03 14.1 0.1 2.9 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange 7TM_GPCR_Srsx PF10320.4 EGD96429.1 - 0.011 14.9 1.2 0.019 14.1 0.8 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Aminotran_1_2 PF00155.16 EGD96430.1 - 1.1e-63 215.3 0.0 1.6e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD96430.1 - 9.3e-05 21.6 0.1 0.00019 20.7 0.0 1.4 2 0 0 2 2 2 1 Beta-eliminating lyase Tmemb_18A PF09771.4 EGD96430.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 Transmembrane protein 188 AMP-binding PF00501.23 EGD96432.1 - 2.5e-40 138.1 0.0 3.4e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD96432.1 - 0.00069 20.5 0.3 0.002 19.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Peptidase_M16_C PF05193.16 EGD96433.1 - 2.7e-46 157.5 0.0 1.9e-45 154.7 0.0 2.3 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGD96433.1 - 7.9e-40 136.0 0.0 8.1e-39 132.7 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Abhydrolase_2 PF02230.11 EGD96434.1 - 1.1e-27 96.9 0.0 7e-18 64.8 0.0 2.5 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGD96434.1 - 8e-07 29.1 0.3 1.6e-06 28.1 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD96434.1 - 3.1e-05 23.7 0.1 5.1e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGD96434.1 - 0.00041 19.6 0.0 0.00071 18.8 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EGD96434.1 - 0.054 13.0 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Tom22 PF04281.8 EGD96435.1 - 1.2e-53 180.3 0.9 1.4e-53 180.1 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 YL1 PF05764.8 EGD96435.1 - 9.2 5.7 7.7 13 5.3 5.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF4211 PF13926.1 EGD96436.1 - 3.3e-45 153.2 0.1 8.2e-45 151.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) DUF4449 PF14613.1 EGD96437.1 - 1.6e-67 226.4 0.7 1.6e-67 226.4 0.5 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) Peptidase_M35 PF02102.10 EGD96438.1 - 5e-72 242.5 0.0 6e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGD96438.1 - 1.5e-06 28.7 0.0 2.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Ost4 PF10215.4 EGD96439.1 - 8 6.0 6.6 0.86 9.1 0.4 2.4 3 0 0 3 3 3 0 Oligosaccaryltransferase vWA-TerF-like PF10138.4 EGD96440.1 - 1.5e-07 31.4 0.0 2.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Pro-rich PF15240.1 EGD96440.1 - 0.0012 18.9 24.5 0.0012 18.9 17.0 3.4 2 1 1 3 3 3 1 Proline-rich VWA_2 PF13519.1 EGD96440.1 - 0.014 15.5 0.0 0.032 14.3 0.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain E1-E2_ATPase PF00122.15 EGD96441.1 - 1.3e-19 70.2 2.7 1.4e-19 70.0 0.0 2.5 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.21 EGD96441.1 - 4.2e-19 69.8 0.3 1.4e-13 51.8 0.2 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGD96441.1 - 1.2e-13 51.6 0.2 1.1e-12 48.4 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD96441.1 - 3.4e-12 46.1 0.0 1.1e-11 44.5 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGD96441.1 - 0.002 17.7 0.2 0.0066 16.0 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Homeobox PF00046.24 EGD96443.1 - 3.1e-20 71.5 2.5 6.5e-20 70.5 1.7 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EGD96443.1 - 6.5e-05 22.5 0.3 0.00019 21.0 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain PGP_phosphatase PF09419.5 EGD96444.1 - 9.8e-52 174.6 0.0 1.2e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EGD96444.1 - 2e-05 24.1 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EGD96444.1 - 0.00047 20.6 0.7 0.74 10.1 0.2 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF4571 PF15137.1 EGD96444.1 - 0.06 12.7 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) Streptin-Immun PF11083.3 EGD96444.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein LSM PF01423.17 EGD96445.1 - 5.4e-14 51.4 0.3 7.1e-14 51.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGD96445.1 - 0.045 13.6 0.1 0.072 13.0 0.1 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Adaptin_binding PF10199.4 EGD96446.1 - 6.1e-17 62.1 4.9 6.1e-17 62.1 3.4 1.8 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 PTPLA PF04387.9 EGD96447.1 - 5.1e-35 120.3 8.5 8.3e-26 90.3 0.1 2.9 1 1 1 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA SRP72 PF08492.7 EGD96448.1 - 2.2e-14 53.5 4.7 6e-14 52.1 3.2 1.7 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_19 PF14559.1 EGD96448.1 - 2.2e-06 27.8 3.4 0.022 15.0 0.0 4.9 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EGD96448.1 - 0.0021 18.1 0.4 2.2 8.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD96448.1 - 0.01 15.5 0.1 30 4.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGD96448.1 - 0.045 13.6 7.7 20 5.3 0.7 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGD96448.1 - 0.51 10.0 2.1 1.2e+02 2.5 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGD96448.1 - 1.2 9.0 4.1 1.4 8.8 0.0 3.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGD96448.1 - 5.9 6.8 7.7 14 5.6 0.2 4.6 5 2 2 7 7 7 0 Tetratricopeptide repeat Homeobox_KN PF05920.6 EGD96449.1 - 5.1e-19 67.6 1.1 1.2e-18 66.5 0.7 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EGD96449.1 - 0.00017 21.1 0.2 0.0003 20.3 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain FAD_binding_1 PF00667.15 EGD96450.1 - 2.4e-44 151.3 0.0 3.4e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EGD96450.1 - 1.3e-09 38.5 0.0 4.1e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Med20 PF08612.6 EGD96453.1 - 8.4e-58 195.1 0.0 1.1e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex EF-hand_1 PF00036.27 EGD96454.1 - 3.1e-41 135.5 11.5 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGD96454.1 - 9.2e-37 125.0 5.9 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EGD96454.1 - 1.5e-34 117.3 11.8 6.8e-16 57.6 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EGD96454.1 - 1.5e-30 102.3 6.8 3.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGD96454.1 - 1.8e-26 90.2 7.7 1.9e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EGD96454.1 - 1.2e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EGD96454.1 - 5.1e-10 39.0 1.5 0.00063 19.4 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGD96454.1 - 1.6e-08 34.5 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EGD96454.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EGD96454.1 - 5.8e-07 29.3 2.4 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EGD96454.1 - 0.00015 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EGD96454.1 - 0.0004 19.9 0.1 0.064 12.8 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 EGD96454.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EGD96454.1 - 0.0027 17.6 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 EGD96454.1 - 0.0059 16.9 1.4 1.8 8.9 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 EGD96454.1 - 0.025 14.9 0.4 8.4 6.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EGD96454.1 - 0.14 11.8 2.4 0.84 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 EGD96454.1 - 0.28 10.8 4.1 0.59 9.7 0.3 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 EGD96454.1 - 0.43 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 EGD96455.1 - 5.4e-18 64.4 2.4 1.9e-17 62.7 1.7 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EGD96455.1 - 1.5e-10 41.1 0.4 1.5e-10 41.1 0.2 2.4 2 1 0 2 2 2 1 Syntaxin DUF3357 PF11837.3 EGD96455.1 - 0.062 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) MCPsignal PF00015.16 EGD96455.1 - 0.12 11.8 6.8 0.046 13.2 0.9 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CTD_bind PF04818.8 EGD96456.1 - 5.4e-20 71.3 0.1 1.1e-19 70.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Clathrin_lg_ch PF01086.12 EGD96457.1 - 2.5e-69 233.6 3.0 2.9e-69 233.4 2.1 1.0 1 0 0 1 1 1 1 Clathrin light chain ATP-synt_B PF00430.13 EGD96457.1 - 2 8.2 7.3 3.1 7.6 5.0 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Acyl_transf_3 PF01757.17 EGD96458.1 - 2.2e-17 62.9 20.5 2.8e-17 62.6 14.2 1.0 1 0 0 1 1 1 1 Acyltransferase family DUF2953 PF11167.3 EGD96458.1 - 3.6 7.5 7.0 8.8 6.3 0.3 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2953) Mannosyl_trans3 PF11051.3 EGD96460.1 - 1.7e-69 234.2 0.0 5.1e-69 232.6 0.0 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative CDC37_N PF03234.9 EGD96461.1 - 1.4e-60 204.6 5.5 1.4e-60 204.6 3.8 2.4 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EGD96461.1 - 1.2e-45 155.0 0.5 3.1e-45 153.7 0.0 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EGD96461.1 - 3.3e-27 94.2 2.7 3.3e-27 94.2 1.8 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain MecA_N PF05223.6 EGD96461.1 - 0.013 15.5 0.7 0.013 15.5 0.5 2.5 3 0 0 3 3 3 0 NTF2-like N-terminal transpeptidase domain DUF77 PF01910.12 EGD96461.1 - 0.053 13.2 0.4 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF77 ABC_membrane PF00664.18 EGD96462.1 - 8e-41 140.2 12.5 1e-40 139.9 8.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGD96462.1 - 2.5e-35 121.7 0.0 7.7e-35 120.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EGD96462.1 - 6.8e-07 28.7 0.1 3.5e-05 23.1 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGD96462.1 - 0.00029 20.8 0.1 0.00029 20.8 0.1 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.1 EGD96462.1 - 0.00037 20.5 0.2 0.85 9.5 0.1 2.4 1 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGD96462.1 - 0.00086 19.4 0.2 0.0057 16.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGD96462.1 - 0.0014 18.0 0.6 0.0036 16.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGD96462.1 - 0.0049 17.6 0.0 0.012 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGD96462.1 - 0.0059 16.0 0.4 0.072 12.4 0.3 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGD96462.1 - 0.0097 15.3 0.1 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_10 PF12846.2 EGD96462.1 - 0.012 15.0 0.7 0.07 12.5 0.2 2.1 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 EGD96462.1 - 0.012 15.7 0.0 0.08 13.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EGD96462.1 - 0.013 15.5 0.1 0.27 11.2 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain ABC_ATPase PF09818.4 EGD96462.1 - 0.026 13.1 0.6 0.12 10.9 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.1 EGD96462.1 - 0.041 14.1 0.1 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGD96462.1 - 0.062 12.4 0.0 0.16 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EGD96462.1 - 0.095 12.4 0.1 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EGD96462.1 - 0.18 11.7 3.2 0.36 10.7 0.3 2.9 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Nucleoside_tran PF01733.13 EGD96463.1 - 8.9e-39 133.4 14.3 1.3e-37 129.6 8.3 2.9 1 1 1 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 EGD96463.1 - 5.2e-06 25.4 34.9 6.5e-05 21.8 7.1 2.8 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF843 PF05814.6 EGD96463.1 - 0.74 9.6 2.9 1.5 8.7 0.2 2.6 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) OST3_OST6 PF04756.8 EGD96463.1 - 4.2 6.8 8.4 1.6 8.2 0.7 3.2 2 2 1 3 3 3 0 OST3 / OST6 family Metallophos_2 PF12850.2 EGD96466.1 - 1.5e-10 41.1 0.0 3.2e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGD96466.1 - 2.5e-08 33.5 0.1 1.2e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3635 PF12330.3 EGD96467.1 - 4e-07 30.0 0.0 1.1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) APH PF01636.18 EGD96467.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2404 PF10296.4 EGD96468.1 - 0.00011 22.2 0.0 0.0004 20.4 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF1682 PF07946.9 EGD96469.1 - 3.2e-106 354.8 0.7 3.8e-106 354.5 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) PBP_sp32 PF07222.7 EGD96469.1 - 1.9 7.5 9.3 3 6.9 6.4 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 COX7a PF02238.10 EGD96470.1 - 0.039 13.6 0.2 0.067 12.9 0.1 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIa SYF2 PF08231.7 EGD96473.1 - 1e-53 181.5 16.3 1e-53 181.5 11.3 2.2 2 0 0 2 2 2 1 SYF2 splicing factor ARD PF03079.9 EGD96473.1 - 0.068 13.1 0.6 0.068 13.1 0.4 3.5 2 1 1 3 3 3 0 ARD/ARD' family NAD_binding_10 PF13460.1 EGD96474.1 - 3.6e-10 40.1 0.0 1.9e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGD96474.1 - 2.3e-08 33.7 0.0 6.8e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD96474.1 - 2.3e-06 26.5 0.0 1.1e-05 24.3 0.0 1.9 1 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGD96474.1 - 2.5e-05 24.2 0.1 0.00015 21.7 0.0 2.2 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EGD96474.1 - 0.00055 18.9 0.4 0.021 13.7 0.2 3.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EGD96474.1 - 0.017 14.3 0.0 0.034 13.3 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family KR PF08659.5 EGD96474.1 - 0.021 14.4 0.0 0.14 11.7 0.0 2.2 1 1 1 2 2 2 0 KR domain RmlD_sub_bind PF04321.12 EGD96474.1 - 0.026 13.4 0.0 0.064 12.1 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Pox_RNA_Pol_19 PF05320.7 EGD96474.1 - 0.03 14.0 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Polysacc_synt_2 PF02719.10 EGD96474.1 - 0.08 11.8 0.0 0.3 9.9 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein YEATS PF03366.11 EGD96475.1 - 1.5e-35 120.7 0.5 2.3e-35 120.1 0.3 1.2 1 0 0 1 1 1 1 YEATS family Cid2 PF09774.4 EGD96475.1 - 0.07 13.2 0.1 0.098 12.7 0.1 1.3 1 0 0 1 1 1 0 Caffeine-induced death protein 2 Rep_fac_C PF08542.6 EGD96476.1 - 1.3e-21 76.3 0.1 3.1e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGD96476.1 - 3.3e-11 43.1 0.0 2.7e-09 36.8 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EGD96476.1 - 4.2e-11 43.1 0.0 7.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGD96476.1 - 7e-07 29.1 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD96476.1 - 7e-06 26.1 0.0 0.00017 21.6 0.0 2.4 1 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EGD96476.1 - 1.1e-05 24.6 0.0 3e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EGD96476.1 - 1.5e-05 23.9 0.0 0.051 12.2 0.0 2.5 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EGD96476.1 - 2.1e-05 24.6 0.1 0.036 14.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EGD96476.1 - 2.3e-05 24.0 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EGD96476.1 - 0.00016 21.2 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EGD96476.1 - 0.00058 19.3 0.0 0.085 12.2 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain AAA_19 PF13245.1 EGD96476.1 - 0.0013 18.4 0.1 0.0042 16.8 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain DNA_pol3_delta PF06144.8 EGD96476.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DEAD PF00270.24 EGD96476.1 - 0.0018 17.8 0.1 0.19 11.2 0.0 2.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 EGD96476.1 - 0.0019 17.5 0.1 0.1 12.0 0.0 2.7 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EGD96476.1 - 0.0024 17.0 0.0 0.027 13.6 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EGD96476.1 - 0.0048 16.6 0.2 0.033 13.8 0.1 2.2 1 1 1 2 2 2 1 NTPase ArgK PF03308.11 EGD96476.1 - 0.0087 14.8 0.1 0.022 13.5 0.0 1.5 1 1 1 2 2 2 1 ArgK protein AAA_11 PF13086.1 EGD96476.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGD96476.1 - 0.019 15.2 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGD96476.1 - 0.027 13.9 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 EGD96476.1 - 0.044 12.9 0.0 0.093 11.9 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_31 PF13614.1 EGD96476.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain His_Phos_2 PF00328.17 EGD96477.1 - 1.2e-10 41.3 0.0 2.5e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1338 PF07063.8 EGD96478.1 - 1.5e-70 237.6 0.0 4.9e-69 232.7 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1338) BID PF06393.6 EGD96478.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 BH3 interacting domain (BID) DUF410 PF04190.8 EGD96480.1 - 2.6e-45 155.0 0.0 3e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RAI1 PF08652.6 EGD96481.1 - 3.2e-27 94.0 0.0 5.7e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease IPPT PF01715.12 EGD96482.1 - 1.5e-51 174.8 5.0 7.3e-48 162.7 3.5 3.1 1 1 0 1 1 1 1 IPP transferase AAA_33 PF13671.1 EGD96482.1 - 1.5e-05 24.8 0.1 0.064 13.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain IPT PF01745.11 EGD96482.1 - 4.5e-05 22.7 0.1 0.00014 21.1 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase AAA_17 PF13207.1 EGD96482.1 - 0.001 19.8 0.0 0.001 19.8 0.0 3.0 3 1 0 3 3 3 1 AAA domain zf-C2H2_jaz PF12171.3 EGD96482.1 - 0.0028 17.7 0.0 0.0053 16.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_25 PF13481.1 EGD96482.1 - 0.0049 16.2 0.2 0.038 13.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain zf-C2H2_2 PF12756.2 EGD96482.1 - 0.0052 16.8 0.5 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EGD96482.1 - 0.0069 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_18 PF13238.1 EGD96482.1 - 0.025 14.8 8.6 0.63 10.3 0.0 3.5 3 1 1 4 4 4 0 AAA domain AAA_19 PF13245.1 EGD96482.1 - 0.038 13.7 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain VASP_tetra PF08776.6 EGD96482.1 - 0.045 13.0 4.9 0.076 12.3 0.3 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain PhoH PF02562.11 EGD96482.1 - 0.06 12.5 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF87 PF01935.12 EGD96482.1 - 0.9 9.3 6.9 0.84 9.4 0.1 2.9 2 1 0 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EGD96482.1 - 8.9 6.5 8.9 28 4.9 0.1 2.9 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EGD96483.1 - 2.6e-05 24.5 0.0 9.9e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGD96483.1 - 0.00079 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EGD96483.1 - 0.061 12.5 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EGD96483.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.27 EGD96484.1 - 9.9e-60 196.4 32.9 2.6e-09 36.6 0.0 12.8 14 0 0 14 14 14 10 WD domain, G-beta repeat Urm1 PF09138.6 EGD96485.1 - 4.8e-34 116.3 0.0 5.6e-34 116.1 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EGD96485.1 - 0.031 14.6 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 ThiS family 6PF2K PF01591.13 EGD96486.1 - 6.6e-62 208.4 0.0 1e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGD96486.1 - 4.9e-21 75.4 0.4 7.3e-21 74.9 0.3 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EGD96486.1 - 0.00024 21.9 0.1 0.00081 20.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGD96486.1 - 0.006 16.4 0.0 0.028 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EGD96486.1 - 0.088 12.4 0.0 0.36 10.4 0.0 1.9 1 1 0 1 1 1 0 Adenylylsulphate kinase Porin_3 PF01459.17 EGD96487.1 - 2.6e-78 263.0 0.0 3e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 EGD96487.1 - 0.012 15.0 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.20 EGD96490.1 - 4.5e-62 209.5 0.0 6e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96490.1 - 5.3e-24 84.6 0.0 6.5e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD96490.1 - 9.9e-07 27.9 0.0 2.2e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGD96490.1 - 0.0017 18.1 0.2 0.019 14.6 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD96490.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 EGD96491.1 - 1.5e-81 272.4 0.5 3.7e-81 271.1 0.0 1.8 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 EGD96491.1 - 9.8e-59 198.6 0.1 1.5e-58 198.0 0.1 1.3 1 0 0 1 1 1 1 MIF4G like YadA_stalk PF05662.9 EGD96492.1 - 0.37 10.6 2.9 0.25 11.1 0.6 1.8 1 1 1 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin WD40 PF00400.27 EGD96493.1 - 1.9e-72 236.7 12.8 6.5e-12 44.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EGD96493.1 - 3.4e-26 91.2 10.1 5.1e-26 90.6 7.0 1.3 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EGD96493.1 - 4e-06 25.3 2.2 0.00024 19.5 0.2 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EGD96493.1 - 0.00062 19.5 0.0 0.04 13.6 0.0 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGD96493.1 - 0.0064 14.6 0.1 0.15 10.1 0.1 2.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 EGD96493.1 - 0.015 14.4 0.0 5.4 6.0 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EGD96493.1 - 0.022 13.5 0.1 1.4 7.6 0.0 3.2 2 1 0 2 2 2 0 Nup133 N terminal like MMS1_N PF10433.4 EGD96493.1 - 0.21 9.6 0.0 8.1 4.4 0.0 2.4 1 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term zf-C2H2 PF00096.21 EGD96495.1 - 4.3e-19 67.6 23.0 4.1e-05 23.6 0.7 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD96495.1 - 7.6e-19 66.9 21.9 5.8e-08 32.6 1.6 4.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGD96495.1 - 7.3e-15 54.1 19.1 0.0013 18.9 0.6 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EGD96495.1 - 8.2e-05 22.6 7.0 0.27 11.5 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type VCX_VCY PF15231.1 EGD96495.1 - 0.0085 16.5 1.0 0.0085 16.5 0.7 1.7 2 0 0 2 2 2 1 Variable charge X/Y family Zn-ribbon_8 PF09723.5 EGD96495.1 - 0.99 9.4 8.6 14 5.7 0.1 4.1 4 0 0 4 4 4 0 Zinc ribbon domain zf-LYAR PF08790.6 EGD96495.1 - 3.1 7.5 10.1 20 4.9 0.2 4.1 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Ogr_Delta PF04606.7 EGD96495.1 - 4.2 7.1 10.9 2.1 8.0 0.1 4.2 5 0 0 5 5 5 0 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.1 EGD96495.1 - 7.7 6.5 13.4 1.7 8.6 0.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger Mito_carr PF00153.22 EGD96496.1 - 1.4e-69 229.8 3.9 4.5e-22 77.5 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.7 EGD96497.1 - 1.6e-14 53.0 0.1 1.8e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 TOM7 family NUMOD3 PF07460.6 EGD96497.1 - 0.06 13.2 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) RRM_1 PF00076.17 EGD96498.1 - 5.3e-27 93.2 0.2 1.1e-15 56.9 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD96498.1 - 2.4e-13 49.6 0.1 5.1e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD96498.1 - 3.5e-12 46.1 0.1 2.9e-07 30.3 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGD96498.1 - 0.0059 16.3 0.3 0.48 10.2 0.1 2.2 2 0 0 2 2 2 1 Limkain b1 Cas_Cas2CT1978 PF09707.5 EGD96498.1 - 0.038 13.9 0.0 4.3 7.3 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) OB_RNB PF08206.6 EGD96498.1 - 0.14 11.7 0.1 9 5.8 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF2015 PF09435.5 EGD96499.1 - 3e-42 143.4 0.0 3.4e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 EGD96500.1 - 1.7e-35 121.9 0.1 2.1e-35 121.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.18 EGD96501.1 - 3.5e-44 150.0 0.0 5.4e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EGD96501.1 - 8.7e-39 133.0 0.0 1.2e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EGD96501.1 - 0.0004 19.1 0.0 0.00056 18.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EGD96501.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase TRAPP PF04051.11 EGD96502.1 - 1.9e-42 144.3 0.0 2.2e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Glyco_transf_90 PF05686.7 EGD96503.1 - 4.9e-18 64.9 7.2 2e-13 49.8 3.2 3.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 PINIT PF14324.1 EGD96504.1 - 1e-40 139.1 0.0 1.9e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EGD96504.1 - 1.1e-21 76.0 7.0 2.1e-21 75.1 4.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EGD96504.1 - 3.1e-07 29.7 0.4 8e-07 28.4 0.2 1.7 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 EGD96504.1 - 2.8e-05 23.5 2.2 5.9e-05 22.5 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.10 EGD96504.1 - 0.015 14.8 0.1 0.059 12.9 0.0 2.0 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger DUF2423 PF10338.4 EGD96505.1 - 5.4e-19 67.8 1.0 5.4e-19 67.8 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Phosphodiest PF01663.17 EGD96506.1 - 1.5e-19 70.5 1.1 7e-18 65.0 0.8 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EGD96506.1 - 0.004 16.5 0.1 0.0092 15.3 0.1 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EGD96506.1 - 0.032 13.4 0.0 0.36 9.9 0.0 2.1 2 0 0 2 2 2 0 Sulfatase AflR PF08493.5 EGD96508.1 - 0.023 13.7 0.3 0.044 12.8 0.2 1.5 1 0 0 1 1 1 0 Aflatoxin regulatory protein Melittin PF01372.12 EGD96509.1 - 0.12 11.7 1.3 0.16 11.3 0.1 1.9 2 0 0 2 2 2 0 Melittin Amidohydro_2 PF04909.9 EGD96510.1 - 3.3e-10 39.9 0.2 1.1e-09 38.3 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGD96510.1 - 1.2e-07 31.7 0.3 2.1e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.1 EGD96510.1 - 0.0057 16.8 0.2 0.039 14.1 0.1 2.3 2 1 1 3 3 3 1 CoA binding domain DnaJ-X PF14308.1 EGD96511.1 - 1.5e-74 249.6 5.4 1.5e-74 249.6 3.7 2.9 2 1 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EGD96511.1 - 6.3e-26 89.8 0.3 1.8e-25 88.4 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain Iron_permease PF04120.7 EGD96512.1 - 6.6 6.3 5.6 0.47 10.0 0.3 1.7 2 0 0 2 2 2 0 Low affinity iron permease IMS PF00817.15 EGD96513.1 - 1.7e-41 141.5 1.1 2.9e-41 140.7 0.3 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EGD96513.1 - 5.4e-14 52.2 0.1 1.1e-13 51.1 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EGD96513.1 - 3.4e-05 23.6 0.0 9.6e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Moricin PF06451.6 EGD96513.1 - 0.0087 15.5 0.4 3 7.3 0.0 3.0 3 0 0 3 3 3 2 Moricin FHA PF00498.21 EGD96514.1 - 1e-05 25.5 0.2 2e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 FHA domain Acetyltransf_10 PF13673.1 EGD96515.1 - 4.8e-07 29.9 0.0 1.6e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD96515.1 - 1.9e-05 24.6 1.0 3.1e-05 23.9 0.1 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD96515.1 - 3.9e-05 23.7 0.0 9.1e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD96515.1 - 0.038 13.8 0.0 0.08 12.7 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD96515.1 - 0.14 11.9 0.0 0.69 9.7 0.0 2.2 2 1 0 2 2 2 0 FR47-like protein Ferritin_2 PF13668.1 EGD96516.1 - 5.1e-13 49.1 0.1 8.4e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.19 EGD96517.1 - 5.1e-19 68.1 20.2 1.3e-10 40.4 3.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.20 EGD96519.1 - 1.3e-31 109.7 0.0 2e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96519.1 - 3.7e-11 42.5 0.0 6.9e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase AMP-binding PF00501.23 EGD96520.1 - 1.6e-77 260.6 0.0 2e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD96520.1 - 2.1e-10 41.3 0.3 4.6e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EGD96521.1 - 9e-40 136.4 25.7 9e-40 136.4 17.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sensor PF13796.1 EGD96521.1 - 7.4e-05 22.4 7.3 7.4e-05 22.4 5.1 3.7 2 1 0 3 3 3 1 Putative sensor MerE PF05052.7 EGD96521.1 - 0.22 11.5 7.1 0.054 13.4 2.0 2.2 2 0 0 2 2 2 0 MerE protein PepSY_TM_1 PF13172.1 EGD96521.1 - 2.5 7.9 6.5 0.51 10.1 0.3 3.0 2 0 0 2 2 2 0 PepSY-associated TM helix CoA_binding_2 PF13380.1 EGD96523.1 - 1.3e-26 93.0 0.0 1.7e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Methyltransf_11 PF08241.7 EGD96525.1 - 2.5e-22 79.1 0.0 4.4e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD96525.1 - 9.9e-14 51.5 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD96525.1 - 2e-13 50.9 0.0 3.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD96525.1 - 7.9e-13 48.2 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD96525.1 - 9.2e-13 48.2 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD96525.1 - 8.2e-11 42.2 0.0 2.1e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD96525.1 - 4.5e-09 35.7 0.0 4e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGD96525.1 - 8.9e-08 32.1 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD96525.1 - 0.0006 19.2 0.0 0.00098 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EGD96525.1 - 0.0027 16.8 0.0 0.0057 15.7 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.7 EGD96525.1 - 0.0035 16.2 0.0 0.0056 15.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.8 EGD96525.1 - 0.037 13.1 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 EGD96525.1 - 0.05 12.7 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MetW PF07021.7 EGD96525.1 - 0.089 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 EGD96525.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase tRNA_U5-meth_tr PF05958.6 EGD96525.1 - 0.18 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase HIT PF01230.18 EGD96526.1 - 7.4e-23 80.9 0.4 1.3e-22 80.1 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EGD96526.1 - 2e-06 28.0 0.0 3.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGD96526.1 - 0.0087 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Rad4 PF03835.10 EGD96527.1 - 2.6e-29 101.4 0.0 2.6e-29 101.4 0.0 2.4 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EGD96527.1 - 1.8e-28 98.0 0.1 3.1e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 EGD96527.1 - 2.3e-17 63.0 0.0 6.6e-17 61.5 0.0 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 EGD96527.1 - 6.3e-17 60.8 1.4 1.4e-16 59.7 0.1 2.2 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 EGD96527.1 - 0.0014 18.8 0.0 0.0067 16.6 0.0 2.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sigma70_ner PF04546.8 EGD96527.1 - 0.12 11.9 8.9 0.015 14.9 1.7 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region HD_3 PF13023.1 EGD96528.1 - 1e-46 158.7 0.1 1.3e-46 158.4 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EGD96528.1 - 0.0075 16.2 0.0 0.02 14.9 0.0 1.7 1 1 0 1 1 1 1 HD domain HATPase_c_4 PF13749.1 EGD96528.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal HAUS6_N PF14661.1 EGD96529.1 - 2.4e-65 220.3 0.1 2.4e-65 220.3 0.0 1.6 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus cobW PF02492.14 EGD96530.1 - 2.2e-45 154.2 0.3 3.6e-45 153.5 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EGD96530.1 - 7.9e-07 28.7 0.0 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Arch_ATPase PF01637.13 EGD96530.1 - 0.00028 20.6 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase ATP_bind_1 PF03029.12 EGD96530.1 - 0.00079 19.0 0.1 0.0028 17.2 0.0 1.9 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EGD96530.1 - 0.0022 18.2 0.1 0.014 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGD96530.1 - 0.0048 16.8 0.4 0.021 14.7 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.1 EGD96530.1 - 0.0088 15.6 0.0 3.3 7.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EGD96530.1 - 0.009 15.7 0.0 0.049 13.3 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain Auxin_BP PF02041.11 EGD96530.1 - 0.013 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Auxin binding protein UPF0079 PF02367.12 EGD96530.1 - 0.013 15.0 0.0 0.57 9.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 EGD96530.1 - 0.014 15.5 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGD96530.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EGD96530.1 - 0.024 13.5 0.1 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EGD96530.1 - 0.034 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EGD96530.1 - 0.036 13.9 0.1 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGD96530.1 - 0.065 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 EGD96530.1 - 0.066 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EGD96530.1 - 0.084 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.13 EGD96530.1 - 0.087 12.3 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 EGD96530.1 - 0.093 13.0 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EGD96530.1 - 0.1 11.3 0.1 1.2 7.8 0.0 2.4 3 0 0 3 3 3 0 ArgK protein DUF258 PF03193.11 EGD96530.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGD96530.1 - 0.15 11.6 0.2 0.86 9.1 0.0 2.3 3 0 0 3 3 2 0 P-loop containing region of AAA domain Mob1_phocein PF03637.12 EGD96531.1 - 5.1e-24 84.8 0.5 8.3e-24 84.2 0.0 1.5 2 0 0 2 2 2 1 Mob1/phocein family Pkinase PF00069.20 EGD96532.1 - 3.7e-11 42.6 0.1 3.6e-10 39.4 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96532.1 - 5.5e-10 38.7 0.0 4.3e-09 35.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Lon_C PF05362.8 EGD96535.1 - 1.3e-63 214.0 0.0 2.8e-63 212.9 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EGD96535.1 - 3.8e-22 78.8 0.0 1e-21 77.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 EGD96535.1 - 2.9e-14 53.2 1.4 3.8e-14 52.8 0.1 1.8 2 0 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 EGD96535.1 - 4.6e-07 29.6 0.0 9.6e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EGD96535.1 - 1.4e-06 27.8 0.0 3.7e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 EGD96535.1 - 2.2e-06 27.6 0.0 6e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGD96535.1 - 8.1e-06 26.0 0.0 0.00016 21.7 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EGD96535.1 - 1.7e-05 23.6 0.1 4.9e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 PrkA AAA domain AAA_17 PF13207.1 EGD96535.1 - 2.4e-05 25.1 0.2 0.00019 22.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD96535.1 - 2.7e-05 24.2 0.5 0.00055 19.9 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EGD96535.1 - 7.3e-05 21.9 0.1 0.00082 18.4 0.0 2.6 4 0 0 4 4 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EGD96535.1 - 0.0013 19.0 1.9 0.022 15.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGD96535.1 - 0.008 16.0 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EGD96535.1 - 0.0095 15.8 0.5 0.099 12.5 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase ATP-synt_ab PF00006.20 EGD96535.1 - 0.024 14.1 0.1 0.1 12.0 0.0 2.1 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 EGD96535.1 - 0.028 14.1 0.0 0.08 12.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EGD96535.1 - 0.03 13.5 0.0 0.068 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EGD96535.1 - 0.033 13.5 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EGD96535.1 - 0.044 13.1 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGD96535.1 - 0.045 13.4 0.1 0.71 9.5 0.0 2.6 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.17 EGD96535.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EGD96535.1 - 0.08 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Phage_connect_1 PF05135.8 EGD96535.1 - 0.099 12.8 0.6 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein ABC_tran PF00005.22 EGD96535.1 - 0.59 10.4 4.8 0.59 10.4 0.0 2.9 3 0 0 3 3 3 0 ABC transporter APH PF01636.18 EGD96537.1 - 2.5e-13 50.3 0.0 4.2e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD96537.1 - 0.0025 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase CTDII PF01556.13 EGD96538.1 - 2.1e-28 98.0 1.9 3e-21 75.0 0.1 3.5 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EGD96538.1 - 1.3e-23 82.4 0.7 2.8e-23 81.4 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGD96538.1 - 7.2e-10 38.7 21.1 7.2e-10 38.7 14.7 2.0 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 EGD96538.1 - 0.048 13.3 7.8 0.11 12.2 0.6 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family BRO1 PF03097.13 EGD96539.1 - 2.5e-129 431.3 0.3 2.5e-129 431.3 0.2 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EGD96539.1 - 5.6e-99 330.8 15.2 9.1e-99 330.1 10.6 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV SAP30_Sin3_bdg PF13867.1 EGD96540.1 - 2.9e-16 59.0 0.2 1.1e-15 57.2 0.1 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF4466 PF14725.1 EGD96540.1 - 0.016 14.5 0.1 0.016 14.5 0.1 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4466) F-box PF00646.28 EGD96541.1 - 1.8e-05 24.2 0.0 5.9e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD96541.1 - 0.0052 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EGD96541.1 - 0.13 12.2 0.7 0.45 10.5 0.1 2.1 2 0 0 2 2 2 0 PRANC domain zf-H2C2_2 PF13465.1 EGD96542.1 - 4.4e-07 29.8 23.8 8.4e-06 25.8 1.3 4.0 3 1 0 3 3 3 2 Zinc-finger double domain Dicty_REP PF05086.7 EGD96542.1 - 0.0015 16.4 4.4 0.0018 16.1 3.0 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Zip PF02535.17 EGD96542.1 - 0.0054 15.7 13.6 0.0054 15.7 9.4 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter DUF2782 PF11191.3 EGD96542.1 - 0.18 11.7 3.0 0.44 10.5 1.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2782) MOSC PF03473.12 EGD96543.1 - 1.2e-11 44.2 0.0 2.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EGD96543.1 - 1.1e-08 34.7 0.0 6.3e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Amidase PF01425.16 EGD96544.1 - 1.6e-72 244.8 0.0 2.4e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Amidase Rad51 PF08423.6 EGD96545.1 - 3.2e-08 32.8 0.0 8.5e-07 28.1 0.0 2.2 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EGD96545.1 - 4.4e-06 26.2 0.1 4.7e-05 22.8 0.0 2.5 3 1 0 3 3 3 1 AAA domain KaiC PF06745.8 EGD96545.1 - 6.3e-06 25.4 0.0 1.9e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 KaiC RecA PF00154.16 EGD96545.1 - 6.5e-05 22.1 0.0 0.00012 21.2 0.0 1.5 1 0 0 1 1 1 1 recA bacterial DNA recombination protein PhoH PF02562.11 EGD96545.1 - 0.00047 19.4 0.0 0.00077 18.7 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein Zot PF05707.7 EGD96545.1 - 0.0017 17.8 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.12 EGD96545.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_10 PF12846.2 EGD96545.1 - 0.011 15.2 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 EGD96545.1 - 0.012 15.3 0.1 0.021 14.5 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 EGD96545.1 - 0.015 15.5 0.5 0.042 14.1 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EGD96545.1 - 0.058 13.3 0.5 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EGD96545.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.4 EGD96545.1 - 0.069 11.6 0.0 0.069 11.6 0.0 1.7 2 0 0 2 2 2 0 RNA12 protein AAA_22 PF13401.1 EGD96545.1 - 0.085 13.0 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF3306 PF11748.3 EGD96545.1 - 1 10.0 7.1 1.6 9.3 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) FA_desaturase PF00487.19 EGD96547.1 - 1.5e-18 67.1 12.0 1.5e-18 67.1 7.5 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGD96547.1 - 2.9e-17 62.2 0.0 6.7e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_M3 PF01432.15 EGD96548.1 - 1.9e-165 551.3 0.4 2.7e-165 550.8 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M3 Nop14 PF04147.7 EGD96549.1 - 0.0027 15.7 2.1 0.003 15.5 1.5 1.1 1 0 0 1 1 1 1 Nop14-like family Mu-like_Com PF10122.4 EGD96549.1 - 0.11 11.5 0.7 2.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-DHHC PF01529.15 EGD96549.1 - 0.12 11.8 0.2 0.12 11.8 0.1 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase Yippee-Mis18 PF03226.9 EGD96549.1 - 0.12 12.4 0.0 9.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CDC45 PF02724.9 EGD96549.1 - 0.2 9.6 4.5 0.25 9.3 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.6 EGD96549.1 - 2 7.0 4.5 2.7 6.5 3.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2890 PF11081.3 EGD96549.1 - 8 6.4 11.9 0.1 12.6 3.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) EF-hand_7 PF13499.1 EGD96550.1 - 1.5e-14 53.9 0.1 1.3e-10 41.2 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EGD96550.1 - 1e-11 43.6 0.1 0.0017 18.0 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EGD96550.1 - 9.5e-10 37.0 0.0 0.0097 15.1 0.0 3.7 3 1 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EGD96550.1 - 9.6e-10 38.2 0.0 0.00015 21.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EGD96550.1 - 3.9e-07 29.5 0.2 0.00029 20.3 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EGD96550.1 - 0.034 13.5 0.6 3.6 7.0 0.1 3.4 3 0 0 3 3 3 0 EF hand DUF3216 PF11505.3 EGD96550.1 - 0.065 13.0 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) UPF0154 PF03672.8 EGD96550.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF805 PF05656.9 EGD96551.1 - 0.1 12.4 1.7 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF4131 PF13567.1 EGD96551.1 - 8.6 5.7 7.6 15 4.9 5.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Fungal_trans PF04082.13 EGD96552.1 - 2.5e-59 200.2 1.4 5.5e-59 199.1 0.6 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EGD96552.1 - 0.00027 21.1 14.9 0.0035 17.6 2.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD96552.1 - 0.00049 20.2 14.5 0.0038 17.4 1.9 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGD96552.1 - 0.085 13.1 10.4 0.16 12.2 2.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Glyco_transf_90 PF05686.7 EGD96554.1 - 2.1e-13 49.7 0.3 2.5e-12 46.1 0.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 90 Xpo1 PF08389.7 EGD96555.1 - 9.4e-29 100.2 0.2 2.2e-27 95.7 0.1 3.2 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EGD96555.1 - 0.00011 22.0 0.2 0.0023 17.8 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EGD96555.1 - 0.00078 19.6 0.1 0.034 14.4 0.0 3.1 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EGD96555.1 - 0.0077 16.2 0.0 4.6 7.5 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EGD96555.1 - 0.01 16.3 0.2 0.3 11.6 0.0 3.8 3 0 0 3 3 3 0 HEAT-like repeat DUF2267 PF10025.4 EGD96555.1 - 0.49 10.4 4.4 0.93 9.5 0.4 3.5 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2267) LSM PF01423.17 EGD96556.1 - 1.5e-14 53.2 0.4 1.8e-14 52.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain PhnA PF03831.9 EGD96556.1 - 0.11 11.9 0.0 0.81 9.1 0.0 2.1 2 0 0 2 2 2 0 PhnA protein 5-FTHF_cyc-lig PF01812.15 EGD96557.1 - 1.1e-30 106.8 0.0 1.8e-30 106.1 0.0 1.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.4 EGD96558.1 - 6.9e-87 290.2 0.0 7.9e-87 290.0 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal YqeY PF09424.5 EGD96559.1 - 3.2e-21 75.6 6.1 3.9e-21 75.3 4.2 1.1 1 0 0 1 1 1 1 Yqey-like protein Nucleoporin_C PF03177.9 EGD96560.1 - 7.7e-106 354.9 1.3 3.7e-92 309.7 2.1 2.1 1 1 1 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EGD96560.1 - 7.5e-86 288.5 0.1 9.6e-86 288.1 0.1 1.1 1 0 0 1 1 1 1 Nup133 N terminal like DUF2781 PF10914.3 EGD96561.1 - 2.1e-36 124.9 10.6 2.4e-36 124.7 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF619 PF04768.8 EGD96562.1 - 2.9e-52 176.5 0.0 6.6e-52 175.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Pyr_redox PF00070.22 EGD96563.1 - 2e-16 60.1 0.0 2e-12 47.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD96563.1 - 1.3e-13 51.3 0.3 1.2e-11 44.9 0.2 4.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD96563.1 - 7.3e-08 31.7 0.0 1.2e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EGD96563.1 - 7.8e-08 32.6 0.0 5e-05 23.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD96563.1 - 9.2e-06 25.6 0.0 0.0075 16.2 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGD96563.1 - 6.9e-05 22.6 0.6 0.24 11.1 0.0 3.9 3 1 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EGD96563.1 - 0.00011 21.2 0.0 0.21 10.4 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 EGD96563.1 - 0.00035 19.5 0.0 0.43 9.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EGD96563.1 - 0.00054 18.5 0.0 0.13 10.6 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein TrkA_N PF02254.13 EGD96563.1 - 0.00079 19.4 0.0 0.55 10.2 0.0 2.3 2 0 0 2 2 2 2 TrkA-N domain Trp_halogenase PF04820.9 EGD96563.1 - 0.00082 18.1 0.0 5.4 5.5 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EGD96563.1 - 0.0031 16.6 0.0 0.22 10.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 EGD96563.1 - 0.023 14.9 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF1188 PF06690.6 EGD96563.1 - 0.065 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) TPR_12 PF13424.1 EGD96564.1 - 3.4e-35 119.8 2.6 3.2e-10 39.7 0.1 5.9 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 EGD96564.1 - 1.1e-23 82.3 13.0 0.00078 19.2 0.0 8.5 9 0 0 9 9 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 EGD96564.1 - 2e-08 34.6 3.1 0.033 14.8 0.2 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD96564.1 - 2e-07 30.5 5.7 1.4 8.6 0.1 5.9 3 1 1 6 6 6 3 TPR repeat TPR_4 PF07721.9 EGD96564.1 - 1.1e-06 28.5 6.8 0.099 13.1 0.4 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.17 EGD96564.1 - 1.4e-06 27.3 0.0 4e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 EGD96564.1 - 5.7e-06 26.5 5.9 0.7 10.2 0.0 5.2 4 3 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGD96564.1 - 1.6e-05 24.4 5.5 14 5.9 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA_22 PF13401.1 EGD96564.1 - 2.6e-05 24.3 0.0 0.00012 22.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain TPR_1 PF00515.23 EGD96564.1 - 0.00021 20.7 0.6 4 7.2 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGD96564.1 - 0.0005 20.0 0.5 11 6.5 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGD96564.1 - 0.0029 17.2 6.1 44 4.2 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat NACHT PF05729.7 EGD96564.1 - 0.0087 15.7 0.0 0.036 13.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain DUF3427 PF11907.3 EGD96564.1 - 0.0089 15.0 1.3 0.015 14.3 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3427) TPR_14 PF13428.1 EGD96564.1 - 0.011 16.2 14.9 3.2 8.6 0.1 7.0 7 2 2 9 9 7 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 EGD96564.1 - 0.015 14.9 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase Arf PF00025.16 EGD96564.1 - 0.038 13.2 0.0 0.27 10.4 0.0 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_17 PF13207.1 EGD96564.1 - 0.042 14.6 0.1 0.71 10.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.1 EGD96564.1 - 0.15 11.6 0.0 0.43 10.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain TPR_6 PF13174.1 EGD96564.1 - 2.4 8.8 7.6 43 4.8 0.1 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat FlaC_arch PF05377.6 EGD96564.1 - 3.3 7.6 8.3 2.8 7.8 0.1 3.8 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) Arv1 PF04161.8 EGD96565.1 - 8.5e-40 136.8 0.3 4.2e-34 118.2 0.1 2.2 2 0 0 2 2 2 2 Arv1-like family Dabb PF07876.7 EGD96567.1 - 3.8e-16 59.3 0.0 4.2e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Pyrid_oxidase_2 PF13883.1 EGD96567.1 - 0.14 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Aminotran_3 PF00202.16 EGD96569.1 - 2e-89 299.7 0.0 2.4e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III BAR_2 PF10455.4 EGD96570.1 - 2.5e-46 157.8 0.7 6.4e-44 149.9 0.5 2.2 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EGD96570.1 - 4.5e-13 49.2 2.5 1.4e-12 47.6 1.7 1.7 1 1 0 1 1 1 1 BAR domain ATP-synt_B PF00430.13 EGD96570.1 - 0.33 10.7 4.0 0.46 10.2 0.5 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) CcmD PF04995.9 EGD96572.1 - 0.63 9.8 7.4 0.56 9.9 1.1 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Glyco_hydro_72 PF03198.9 EGD96573.1 - 4e-130 433.3 0.8 5e-130 433.0 0.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EGD96573.1 - 7.2e-24 84.0 0.4 1.7e-23 82.9 0.3 1.6 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EGD96573.1 - 0.00016 20.6 0.1 0.00038 19.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EGD96573.1 - 0.056 12.6 0.3 9.7 5.2 0.0 2.4 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) NAD_binding_2 PF03446.10 EGD96574.1 - 1.7e-25 89.7 0.0 3.7e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGD96574.1 - 9.9e-11 41.7 0.8 1.6e-10 41.0 0.5 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 EGD96574.1 - 1.1e-05 25.5 0.0 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EGD96574.1 - 1.2e-05 25.6 1.3 2.7e-05 24.5 0.1 2.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.21 EGD96574.1 - 0.14 11.7 1.4 12 5.4 0.0 2.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Vac7 PF12751.2 EGD96575.1 - 0.05 12.4 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Abhydrolase_6 PF12697.2 EGD96576.1 - 5.4e-21 75.5 0.7 1.1e-20 74.4 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD96576.1 - 7.9e-14 51.7 0.1 3.5e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD96576.1 - 5.9e-08 32.5 0.1 9.6e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGD96576.1 - 0.00018 21.8 0.0 0.00027 21.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EGD96576.1 - 0.0004 20.0 0.1 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S28 PF05577.7 EGD96576.1 - 0.022 13.3 0.0 0.032 12.7 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Thioredoxin PF00085.15 EGD96579.1 - 5.1e-59 196.4 0.0 3.4e-29 100.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EGD96579.1 - 2.2e-18 66.6 1.9 2.9e-18 66.2 0.7 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EGD96579.1 - 6e-15 55.4 0.5 2.5e-06 27.6 0.1 3.5 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGD96579.1 - 8.7e-12 44.9 0.0 5.2e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EGD96579.1 - 1.4e-10 41.1 0.0 0.0044 17.1 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EGD96579.1 - 7.4e-06 25.6 0.0 0.05 13.2 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.1 EGD96579.1 - 0.00016 21.5 0.0 0.3 10.8 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EGD96579.1 - 0.00042 19.8 0.2 0.12 11.9 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin Redoxin PF08534.5 EGD96579.1 - 0.0057 16.1 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 1 Redoxin Thioredoxin_4 PF13462.1 EGD96579.1 - 0.015 15.2 3.2 12 5.8 0.1 3.8 3 2 0 3 3 3 0 Thioredoxin Glutaredoxin PF00462.19 EGD96579.1 - 0.072 13.0 0.3 14 5.7 0.1 3.0 3 1 0 3 3 3 0 Glutaredoxin HSBP1 PF06825.7 EGD96580.1 - 9.5e-20 69.9 1.2 1.3e-19 69.4 0.8 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 EGD96580.1 - 0.00015 21.0 0.7 0.033 13.5 0.0 2.2 1 1 1 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.7 EGD96580.1 - 0.00051 20.2 1.5 0.00066 19.8 1.1 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 EGD96580.1 - 0.0015 18.3 0.5 0.0017 18.1 0.3 1.1 1 0 0 1 1 1 1 Laminin Domain II Baculo_PEP_C PF04513.7 EGD96580.1 - 0.0042 16.9 0.8 0.0051 16.6 0.5 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.10 EGD96580.1 - 0.019 14.1 0.3 0.021 14.0 0.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_I PF06008.9 EGD96580.1 - 0.022 14.1 2.3 0.024 13.9 1.6 1.0 1 0 0 1 1 1 0 Laminin Domain I PilJ PF13675.1 EGD96580.1 - 0.032 14.5 1.6 0.037 14.3 1.1 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term KfrA_N PF11740.3 EGD96580.1 - 0.048 14.1 0.5 0.053 13.9 0.4 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF4094 PF13334.1 EGD96580.1 - 0.056 13.8 1.3 0.068 13.5 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) MRP-S31 PF15433.1 EGD96580.1 - 0.057 12.8 1.1 0.056 12.8 0.7 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 YgbB PF02542.11 EGD96580.1 - 0.058 13.2 0.1 0.06 13.1 0.0 1.1 1 0 0 1 1 1 0 YgbB family Syntaxin-6_N PF09177.6 EGD96580.1 - 0.058 13.7 1.1 0.078 13.3 0.8 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal COG5 PF10392.4 EGD96580.1 - 0.064 13.2 0.3 0.078 12.9 0.2 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Hemagglutinin PF00509.13 EGD96580.1 - 0.069 11.2 1.2 0.075 11.1 0.9 1.0 1 0 0 1 1 1 0 Haemagglutinin TMF_DNA_bd PF12329.3 EGD96580.1 - 0.071 12.9 0.4 0.33 10.7 0.3 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Med9 PF07544.8 EGD96580.1 - 0.073 12.8 0.5 0.1 12.3 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Syntaxin PF00804.20 EGD96580.1 - 0.073 13.2 1.0 0.097 12.8 0.7 1.2 1 0 0 1 1 1 0 Syntaxin DUF2365 PF10157.4 EGD96580.1 - 0.082 12.7 0.2 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) DUF4164 PF13747.1 EGD96580.1 - 0.1 12.7 1.3 0.21 11.7 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF1664 PF07889.7 EGD96580.1 - 0.11 12.3 0.3 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Hormone_1 PF00103.15 EGD96580.1 - 0.12 11.7 0.1 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Somatotropin hormone family BLOC1_2 PF10046.4 EGD96580.1 - 0.12 12.5 0.7 0.25 11.5 0.5 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaG PF03646.10 EGD96580.1 - 0.14 12.3 1.3 0.15 12.1 0.9 1.2 1 0 0 1 1 1 0 FlaG protein tRNA_anti-like PF12869.2 EGD96580.1 - 0.14 11.6 0.5 0.16 11.4 0.3 1.0 1 0 0 1 1 1 0 tRNA_anti-like Tup_N PF08581.5 EGD96580.1 - 0.14 12.3 0.5 0.36 11.0 0.3 1.7 1 1 0 1 1 1 0 Tup N-terminal YvrJ PF12841.2 EGD96580.1 - 0.21 10.8 0.8 1.3 8.3 0.2 2.2 1 1 2 3 3 3 0 YvrJ protein family PspB PF06667.7 EGD96580.1 - 0.52 10.2 1.9 8.8 6.3 1.3 2.1 1 1 0 1 1 1 0 Phage shock protein B IncA PF04156.9 EGD96580.1 - 1 8.9 4.3 2.9 7.4 3.0 1.7 1 1 0 1 1 1 0 IncA protein Ebp2 PF05890.7 EGD96581.1 - 1.4e-89 300.0 15.6 1.4e-89 300.0 10.8 2.5 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 RNase_T PF00929.19 EGD96582.1 - 0.0028 17.9 0.0 0.014 15.6 0.0 2.0 2 0 0 2 2 2 1 Exonuclease DNMT1-RFD PF12047.3 EGD96582.1 - 0.071 12.8 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain E3_UbLigase_EDD PF11547.3 EGD96582.1 - 0.1 12.0 0.9 0.28 10.7 0.6 1.7 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD TATR PF03430.8 EGD96582.1 - 0.17 10.4 2.0 0.25 9.9 1.4 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Drc1-Sld2 PF11719.3 EGD96582.1 - 0.45 9.5 10.2 0.28 10.2 5.9 1.4 1 1 0 1 1 1 0 DNA replication and checkpoint protein TruB_N PF01509.13 EGD96583.1 - 2.4e-19 69.9 0.0 2e-18 66.9 0.0 2.3 2 1 1 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) OHCU_decarbox PF09349.5 EGD96587.1 - 4.7e-41 140.7 0.1 5.6e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase WD40 PF00400.27 EGD96588.1 - 2.3e-23 81.1 5.2 3.8e-07 29.7 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 EGD96588.1 - 0.019 13.1 0.6 1.9 6.4 0.5 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 IKI3 PF04762.7 EGD96588.1 - 0.11 10.3 0.0 6.7 4.3 0.0 2.0 1 1 1 2 2 2 0 IKI3 family Cytochrom_D1 PF02239.11 EGD96588.1 - 0.11 10.7 0.0 0.28 9.4 0.0 1.6 1 1 0 1 1 1 0 Cytochrome D1 heme domain CBM_19 PF03427.8 EGD96588.1 - 0.19 11.5 3.2 0.23 11.2 0.0 2.7 3 0 0 3 3 3 0 Carbohydrate binding domain (family 19) SRP9-21 PF05486.7 EGD96589.1 - 6.3e-29 99.5 0.6 9e-29 99.0 0.4 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.16 EGD96590.1 - 9.3e-120 398.8 1.8 1.1e-119 398.5 1.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Mito_carr PF00153.22 EGD96591.1 - 1.2e-56 188.3 4.0 2.6e-18 65.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EGD96592.1 - 2.5e-10 39.8 5.8 2.4e-06 27.2 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat MRG PF05712.8 EGD96592.1 - 0.04 12.8 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 MRG DUF1308 PF07000.6 EGD96593.1 - 3.4e-79 266.1 0.0 1.6e-78 263.9 0.0 1.8 1 1 1 2 2 2 2 Protein of unknown function (DUF1308) Syntaxin-18_N PF10496.4 EGD96593.1 - 0.036 13.8 0.1 0.091 12.6 0.1 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DUF3508 PF12018.3 EGD96593.1 - 0.044 12.7 0.2 0.091 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) Lung_7-TM_R PF06814.8 EGD96594.1 - 3.3e-73 246.2 19.7 4e-73 245.9 13.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4131 PF13567.1 EGD96594.1 - 5 6.5 10.7 2.1 7.7 1.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF2392 PF10288.4 EGD96595.1 - 5.3e-24 84.6 0.0 8.3e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DUF4112 PF13430.1 EGD96596.1 - 4.2e-35 119.8 0.2 5.5e-35 119.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.8 EGD96597.1 - 8.4e-37 124.9 1.7 1.5e-36 124.1 1.1 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EGD96597.1 - 5.6e-15 55.1 0.0 1.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GCV_T PF01571.16 EGD96599.1 - 3.5e-13 49.4 0.0 6.3e-13 48.5 0.0 1.4 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EGD96599.1 - 0.00035 20.5 0.0 0.00061 19.7 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Mei4 PF13971.1 EGD96600.1 - 0.012 14.6 0.1 0.022 13.7 0.1 1.5 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 DnaJ PF00226.26 EGD96601.1 - 9.9e-20 70.0 0.1 2.8e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 EGD96601.1 - 0.03 13.9 0.3 0.11 12.1 0.2 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIG-L PF02585.12 EGD96603.1 - 1.3e-27 96.8 0.0 2e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.2 EGD96604.1 - 7.2e-29 99.7 0.0 1.7e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 EGD96604.1 - 2e-05 24.4 1.3 0.04 13.8 0.1 3.2 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EGD96604.1 - 0.0001 22.2 0.1 0.0029 17.7 0.0 3.1 3 0 0 3 3 3 1 Pentatricopeptide repeat domain FCD PF07729.7 EGD96604.1 - 0.019 15.2 0.7 0.04 14.2 0.5 1.5 1 0 0 1 1 1 0 FCD domain PPR PF01535.15 EGD96604.1 - 0.031 14.2 0.3 8.5 6.6 0.0 3.5 3 0 0 3 3 3 0 PPR repeat DUF1216 PF06746.6 EGD96604.1 - 0.064 13.0 0.2 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) GTP_EFTU PF00009.22 EGD96605.1 - 5.8e-22 78.0 0.2 2.4e-21 76.0 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGD96605.1 - 9.5e-16 57.7 0.0 2.1e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain LSM PF01423.17 EGD96605.1 - 4.5e-12 45.3 0.2 1.4e-11 43.7 0.2 1.9 1 0 0 1 1 1 1 LSM domain GTP_EFTU_D2 PF03144.20 EGD96605.1 - 5.2e-07 29.6 1.5 5.2e-06 26.4 0.6 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EGD96605.1 - 0.0012 18.3 0.5 1 8.8 0.0 3.4 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EGD96605.1 - 0.0034 17.3 0.0 0.0077 16.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD96605.1 - 0.0046 17.4 0.1 0.032 14.7 0.1 2.5 1 1 0 1 1 1 1 Miro-like protein MobB PF03205.9 EGD96605.1 - 0.02 14.6 0.3 0.05 13.2 0.2 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EGD96605.1 - 0.025 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EGD96605.1 - 0.1 12.4 0.3 0.33 10.7 0.1 2.0 2 0 0 2 2 2 0 Dynamin family Lyase_1 PF00206.15 EGD96607.1 - 1e-21 77.4 0.1 1.9e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EGD96607.1 - 2.2e-15 56.3 0.0 6.7e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus SNF2_N PF00176.18 EGD96608.1 - 4.3e-70 235.8 0.0 5.9e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EGD96608.1 - 6.9e-23 80.6 0.0 1.4e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EGD96608.1 - 6.2e-13 48.4 0.0 1.4e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EGD96608.1 - 4.5e-06 26.5 12.9 9.2e-06 25.5 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD96608.1 - 0.00019 21.0 9.8 0.00036 20.1 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD96608.1 - 0.0012 18.6 10.9 0.003 17.3 7.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGD96608.1 - 0.0016 18.0 12.6 0.0033 17.0 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD96608.1 - 0.019 14.6 11.0 0.04 13.6 7.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGD96608.1 - 0.37 10.7 12.2 0.78 9.6 8.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD96608.1 - 0.95 9.2 8.8 3.1 7.5 6.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger SQS_PSY PF00494.14 EGD96609.1 - 1.7e-45 155.3 0.0 3.1e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase Soyouz_module PF14313.1 EGD96609.1 - 0.038 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) CorA PF01544.13 EGD96610.1 - 7.4e-26 90.8 5.0 4.6e-17 61.9 1.0 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Brr6_like_C_C PF10104.4 EGD96610.1 - 0.28 10.6 1.7 0.35 10.3 0.1 1.9 1 1 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain DNA_pol_A PF00476.15 EGD96611.1 - 3.8e-99 331.9 0.0 5.8e-99 331.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EGD96611.1 - 0.01 15.3 0.1 0.43 10.0 0.1 2.5 1 1 0 1 1 1 1 3'-5' exonuclease zf-C3HC4_3 PF13920.1 EGD96612.1 - 6.2e-10 38.6 4.5 9.2e-10 38.0 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD96612.1 - 8e-10 38.3 4.6 1.2e-09 37.7 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGD96612.1 - 2.4e-09 37.0 5.5 4.4e-09 36.2 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD96612.1 - 5.7e-09 35.4 4.2 1.7e-08 33.9 3.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD96612.1 - 2.9e-07 30.1 5.6 5.1e-07 29.3 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGD96612.1 - 1.4e-06 28.0 6.8 1.8e-05 24.5 5.3 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD96612.1 - 0.00015 21.3 5.5 0.00086 18.9 1.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGD96612.1 - 0.019 15.0 0.5 0.034 14.2 0.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 EGD96612.1 - 0.073 12.5 1.7 0.15 11.6 1.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.9 EGD96612.1 - 0.082 12.3 0.5 3.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF2616 PF11077.3 EGD96612.1 - 0.13 11.7 0.9 0.22 11.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) FANCL_C PF11793.3 EGD96612.1 - 0.14 12.1 3.1 0.66 9.9 2.3 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-Apc11 PF12861.2 EGD96612.1 - 0.28 11.0 3.6 1.8 8.4 2.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF776 PF05604.6 EGD96612.1 - 0.28 11.3 4.1 0.51 10.5 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF776) Prok-RING_4 PF14447.1 EGD96612.1 - 0.8 9.2 5.6 1.1 8.8 1.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.16 EGD96612.1 - 1.4 8.9 4.8 4.2 7.3 3.3 1.9 1 1 0 1 1 1 0 FYVE zinc finger DUF1644 PF07800.7 EGD96612.1 - 1.7 8.4 7.0 1.8 8.4 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_4 PF14570.1 EGD96612.1 - 3 7.4 7.8 17 5.0 5.6 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 EGD96612.1 - 6.1 6.4 7.6 53 3.4 0.2 2.4 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EGD96612.1 - 6.2 6.6 8.2 11 5.8 3.2 2.7 2 1 1 3 3 3 0 zf-RING of BARD1-type protein UPF0052 PF01933.13 EGD96613.1 - 2.4e-52 178.1 0.0 3.2e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 PI3_PI4_kinase PF00454.22 EGD96614.1 - 1.9e-44 151.8 0.1 4e-44 150.8 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EGD96614.1 - 2.5e-40 137.7 0.0 8e-40 136.1 0.0 2.0 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EGD96614.1 - 2.1e-08 33.4 0.1 5.2e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 FATC domain DUF3414 PF11894.3 EGD96615.1 - 0 1344.6 25.9 0 1344.3 17.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Cullin PF00888.17 EGD96616.1 - 7.9e-119 397.8 3.0 1e-118 397.4 2.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGD96616.1 - 1.8e-25 88.5 1.8 4.9e-25 87.1 1.3 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.6 EGD96616.1 - 0.0037 17.1 0.0 0.0095 15.7 0.0 1.7 1 0 0 1 1 1 1 HbrB-like HTH_34 PF13601.1 EGD96616.1 - 0.071 13.1 0.8 5.4 7.1 0.1 2.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain Dak1 PF02733.12 EGD96617.1 - 4.4e-113 377.1 2.3 6e-113 376.6 1.6 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EGD96617.1 - 1.4e-46 158.3 1.5 5.8e-46 156.3 0.3 2.2 2 0 0 2 2 2 1 DAK2 domain Rotamase PF00639.16 EGD96617.1 - 0.073 13.8 0.1 0.25 12.0 0.0 1.9 2 0 0 2 2 2 0 PPIC-type PPIASE domain LSM PF01423.17 EGD96618.1 - 1.3e-15 56.6 0.3 7.9e-14 50.9 0.0 2.1 2 0 0 2 2 2 2 LSM domain CAV_VP3 PF04771.7 EGD96618.1 - 0.083 12.8 0.1 2.9 7.8 0.0 2.2 1 1 1 2 2 2 0 Chicken anaemia virus VP-3 protein GATA PF00320.22 EGD96619.1 - 1.5e-05 24.2 4.7 0.0006 19.0 0.5 2.6 2 0 0 2 2 2 2 GATA zinc finger Rep_fac-A_3 PF08661.6 EGD96620.1 - 7.3e-24 83.7 0.0 8.8e-24 83.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 tRNA_anti-codon PF01336.20 EGD96620.1 - 0.13 12.1 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Glyco_hydro_16 PF00722.16 EGD96621.1 - 4.4e-44 149.9 1.4 7e-44 149.3 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1191 PF06697.7 EGD96621.1 - 0.069 11.9 0.0 0.095 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Prp19_bind PF06991.6 EGD96622.1 - 1.2e-28 100.1 24.6 1.2e-28 100.1 17.1 2.3 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain FXR1P_C PF12235.3 EGD96622.1 - 0.01 15.9 9.0 0.01 15.9 6.2 4.5 3 1 1 4 4 4 0 Fragile X-related 1 protein C terminal TRAPP PF04051.11 EGD96623.1 - 1.9e-34 118.3 0.0 2.4e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NAD_kinase PF01513.16 EGD96624.1 - 2e-72 243.3 0.0 2.5e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Matrix PF00661.16 EGD96626.1 - 0.13 10.5 0.0 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 Viral matrix protein BLVR PF06375.6 EGD96628.1 - 1.9 8.2 22.0 0.19 11.5 3.4 2.1 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) tRNA_synt_1c_R2 PF04557.10 EGD96628.1 - 4 8.1 11.5 7.1 7.3 2.4 2.2 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF1777 PF08648.7 EGD96628.1 - 4.3 7.0 25.0 5 6.8 17.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) FAM60A PF15396.1 EGD96628.1 - 5 6.8 11.5 6.8 6.3 8.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Las1 PF04031.8 EGD96630.1 - 5.6e-38 130.0 0.2 1.4e-37 128.7 0.1 1.7 1 1 0 1 1 1 1 Las1-like Lactamase_B PF00753.22 EGD96631.1 - 3.6e-29 101.8 5.4 4.6e-29 101.4 3.7 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGD96631.1 - 9.9e-06 25.2 0.4 1.4e-05 24.7 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 EGD96631.1 - 0.0094 15.2 0.1 0.02 14.2 0.0 1.5 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Peptidase_S24 PF00717.18 EGD96632.1 - 9.6e-10 37.9 0.1 1.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EGD96632.1 - 0.00011 21.7 0.0 0.0016 17.9 0.0 2.2 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 PBP PF01161.15 EGD96633.1 - 1.3e-10 41.2 0.0 2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF4615 PF15393.1 EGD96633.1 - 0.22 11.7 2.1 0.52 10.5 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4615) ABC_tran_2 PF12848.2 EGD96633.1 - 0.27 11.1 6.0 0.64 9.8 4.2 1.6 1 0 0 1 1 1 0 ABC transporter Ribosomal_L4 PF00573.17 EGD96634.1 - 1.4e-45 155.0 0.0 2e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Acyl-CoA_dh_1 PF00441.19 EGD96634.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Telomere_Sde2 PF13019.1 EGD96634.1 - 0.063 12.9 0.2 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Telomere stability and silencing ECH_C PF13766.1 EGD96635.1 - 1.3e-38 131.7 0.0 2.6e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EGD96635.1 - 6.4e-22 77.8 0.0 3.1e-21 75.6 0.0 2.0 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family RhoGAP PF00620.22 EGD96636.1 - 0.088 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain CBS PF00571.23 EGD96637.1 - 1e-25 89.2 7.5 1.4e-10 40.8 0.3 4.2 4 0 0 4 4 4 4 CBS domain CRAL_TRIO PF00650.15 EGD96638.1 - 4.5e-36 123.7 0.0 6.2e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGD96638.1 - 1e-11 44.7 0.0 3.8e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGD96638.1 - 2.3e-05 24.3 0.0 3.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 EGD96639.1 - 9.6e-61 205.5 0.2 1.2e-60 205.1 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EGD96639.1 - 2.2e-34 118.5 0.0 3.1e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Apc13p PF05839.6 EGD96640.1 - 3.1e-20 71.9 1.0 4.7e-17 61.7 0.0 2.2 1 1 0 2 2 2 2 Apc13p protein IF-2B PF01008.12 EGD96641.1 - 4.9e-70 235.7 0.1 6.3e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Kinesin PF00225.18 EGD96642.1 - 1.4e-112 375.7 0.0 2.3e-112 375.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Bacillus_HBL PF05791.6 EGD96642.1 - 0.01 15.1 5.0 0.022 14.1 0.0 2.6 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF1460 PF07313.7 EGD96642.1 - 0.017 14.3 1.5 0.034 13.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) DUF2422 PF10337.4 EGD96642.1 - 0.13 10.9 2.9 0.86 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) DUF972 PF06156.8 EGD96642.1 - 0.28 11.5 8.6 7.5 6.9 3.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF87 PF01935.12 EGD96642.1 - 2 8.1 10.1 0.73 9.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 EGD96642.1 - 3.1 5.5 8.0 4.8 4.8 5.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 EGD96642.1 - 9.4 5.8 14.3 4.1 7.0 7.8 1.9 2 0 0 2 2 2 0 Mnd1 family Peptidase_C97 PF05903.9 EGD96643.1 - 1.1e-39 135.5 0.0 2.8e-39 134.2 0.0 1.6 2 0 0 2 2 2 1 PPPDE putative peptidase domain PUL PF08324.6 EGD96643.1 - 2.2e-34 118.5 0.1 3.1e-34 118.0 0.1 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 EGD96643.1 - 7.6e-16 57.6 0.0 1.4e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGD96643.1 - 7.5e-05 22.8 0.1 0.00032 20.8 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain DUF2847 PF11009.3 EGD96643.1 - 0.0051 16.3 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Thioredoxin_3 PF13192.1 EGD96643.1 - 0.0053 16.5 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 EGD96643.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Redoxin PF08534.5 EGD96643.1 - 0.032 13.7 0.0 0.091 12.3 0.0 1.7 1 0 0 1 1 1 0 Redoxin T4_deiodinase PF00837.12 EGD96643.1 - 0.044 12.7 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase DSBA PF01323.15 EGD96643.1 - 0.046 13.2 0.0 1.1 8.7 0.0 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain AhpC-TSA PF00578.16 EGD96643.1 - 0.048 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family EF-hand_9 PF14658.1 EGD96644.1 - 0.0039 17.0 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EGD96644.1 - 0.063 12.9 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair Dak2 PF02734.12 EGD96644.1 - 0.069 12.8 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 DAK2 domain FIST_C PF10442.4 EGD96644.1 - 0.08 12.8 0.1 0.14 12.1 0.1 1.5 1 1 0 1 1 1 0 FIST C domain EF-hand_6 PF13405.1 EGD96644.1 - 0.14 12.0 0.0 18 5.5 0.0 3.4 3 1 0 3 3 3 0 EF-hand domain UCH PF00443.24 EGD96645.1 - 4e-33 114.6 0.0 5.6e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD96645.1 - 6.9e-10 38.8 0.0 1.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alb1 PF09135.6 EGD96646.1 - 1.1e-27 96.8 11.0 1.7e-27 96.2 7.6 1.3 1 0 0 1 1 1 1 Alb1 Vps16_N PF04841.8 EGD96647.1 - 1.7e-98 329.9 0.0 2.5e-98 329.3 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EGD96647.1 - 1.4e-83 280.4 0.2 2.3e-83 279.8 0.2 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region IGF2_C PF08365.6 EGD96649.1 - 0.25 11.1 2.8 7.3 6.4 0.0 2.7 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide Bestrophin PF01062.16 EGD96650.1 - 2.9e-45 154.4 0.0 5.1e-45 153.6 0.0 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FHA PF00498.21 EGD96651.1 - 2.2e-14 53.3 0.0 4e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EGD96651.1 - 3.7e-06 26.6 9.4 6.9e-06 25.7 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGD96651.1 - 0.0032 17.5 6.1 0.0064 16.5 4.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGD96651.1 - 0.0072 16.0 6.6 0.013 15.1 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD96651.1 - 0.0098 15.5 8.1 0.019 14.6 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGD96651.1 - 0.041 13.7 2.9 0.083 12.7 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EGD96651.1 - 0.11 12.5 9.9 0.2 11.7 6.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EGD96651.1 - 1.8 8.6 9.2 4.5 7.3 6.4 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EGD96651.1 - 2.2 8.2 6.5 5.4 6.9 4.6 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-H2C2_2 PF13465.1 EGD96651.1 - 4.7 7.6 7.2 0.28 11.5 0.4 2.5 3 0 0 3 3 3 0 Zinc-finger double domain Arm PF00514.18 EGD96653.1 - 5.6e-66 216.3 27.2 3.3e-11 42.5 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGD96653.1 - 3.5e-22 78.4 14.8 3.6e-07 30.3 0.4 7.6 3 2 3 7 7 7 6 HEAT repeats HEAT PF02985.17 EGD96653.1 - 7.8e-19 66.0 13.4 0.032 14.3 0.0 9.6 10 0 0 10 10 10 5 HEAT repeat Adaptin_N PF01602.15 EGD96653.1 - 4.5e-14 51.6 5.8 3.1e-08 32.4 0.1 2.6 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 EGD96653.1 - 2.2e-13 50.2 17.6 0.017 15.6 0.0 8.2 7 3 3 10 10 10 5 HEAT-like repeat KAP PF05804.7 EGD96653.1 - 2.9e-09 35.4 0.4 6.8e-09 34.2 0.1 1.7 1 1 1 2 2 2 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 EGD96653.1 - 1.9e-08 33.7 6.4 0.0001 21.4 2.5 3.1 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.9 EGD96653.1 - 5.3e-08 32.3 0.7 0.0021 17.2 0.3 3.1 2 1 1 3 3 3 2 V-ATPase subunit H HEAT_PBS PF03130.11 EGD96653.1 - 0.0013 19.0 8.7 1 10.0 0.4 6.6 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGD96653.1 - 0.017 15.5 0.1 0.47 10.8 0.0 2.9 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region EXOSC1 PF10447.4 EGD96654.1 - 4.4e-28 97.0 2.5 7.8e-28 96.2 1.8 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EGD96654.1 - 5.7e-15 54.3 0.1 9.1e-15 53.6 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region GTP_EFTU PF00009.22 EGD96655.1 - 2.2e-53 180.4 0.1 5.8e-53 179.1 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EGD96655.1 - 5e-15 55.1 0.0 1.2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EGD96655.1 - 1e-07 31.6 0.0 2.4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EGD96655.1 - 2e-06 27.8 0.0 7e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EGD96655.1 - 4e-06 26.3 0.0 0.00019 20.9 0.0 2.6 1 1 0 1 1 1 1 Elongation factor G, domain IV SET PF00856.23 EGD96655.1 - 0.0083 16.4 0.1 0.048 13.9 0.0 2.2 2 0 0 2 2 2 1 SET domain MMR_HSR1 PF01926.18 EGD96655.1 - 0.01 15.8 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4604 PF15377.1 EGD96656.1 - 3.3e-29 102.1 13.6 3.7e-29 101.9 9.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) CheD PF03975.8 EGD96656.1 - 0.054 13.2 0.1 0.073 12.8 0.1 1.3 1 0 0 1 1 1 0 CheD chemotactic sensory transduction Prp19 PF08606.6 EGD96657.1 - 1.3e-32 111.3 0.3 2.5e-32 110.4 0.2 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EGD96657.1 - 2.6e-13 49.2 11.7 1.5e-06 27.8 0.0 7.1 8 0 0 8 8 8 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EGD96657.1 - 4.8e-09 35.5 0.1 0.00033 19.5 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 EGD96657.1 - 5e-06 26.3 0.0 0.022 14.4 0.0 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGD96657.1 - 0.00049 18.5 0.5 0.12 10.5 0.0 2.3 1 1 0 2 2 2 2 Cytochrome D1 heme domain DUF3312 PF11768.3 EGD96657.1 - 0.038 12.2 0.0 0.061 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) zf-Nse PF11789.3 EGD96657.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit LdpA_C PF12617.3 EGD96657.1 - 0.1 11.8 0.0 0.74 9.0 0.0 2.3 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal DUF3804 PF12707.2 EGD96657.1 - 0.1 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) Cation_efflux PF01545.16 EGD96658.1 - 1.4e-82 277.0 0.0 2.5e-82 276.1 0.0 1.4 1 1 0 1 1 1 1 Cation efflux family DUF202 PF02656.10 EGD96659.1 - 2.6e-19 69.1 1.5 2.6e-19 69.1 1.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Methyltransf_11 PF08241.7 EGD96660.1 - 1.2e-15 57.7 0.0 2e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD96660.1 - 3.1e-14 52.9 0.0 4.2e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD96660.1 - 7.3e-14 51.6 0.0 9.9e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD96660.1 - 1.2e-13 51.6 0.1 2.1e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD96660.1 - 1.4e-12 47.9 0.0 2.4e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD96660.1 - 7.8e-11 42.0 0.4 1.8e-10 40.8 0.3 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD96660.1 - 7.2e-09 35.9 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD96660.1 - 8e-07 28.4 0.0 1.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGD96660.1 - 4.1e-06 26.2 0.0 6.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EGD96660.1 - 9.2e-06 25.3 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EGD96660.1 - 2.3e-05 23.5 0.0 3.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 EGD96660.1 - 0.00017 20.4 0.0 0.00029 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EGD96660.1 - 0.00039 19.5 0.0 0.00054 19.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 EGD96660.1 - 0.0026 17.1 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.14 EGD96660.1 - 0.0057 16.6 0.1 0.027 14.4 0.1 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EGD96660.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EGD96660.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DREV PF05219.7 EGD96660.1 - 0.064 12.1 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.1 EGD96660.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EGD96660.1 - 0.086 13.6 0.1 6.5 7.6 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain M16C_assoc PF08367.6 EGD96661.1 - 7.7e-57 191.9 0.1 2.9e-56 190.1 0.1 1.9 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EGD96661.1 - 5.1e-28 97.9 0.0 3.4e-14 52.9 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGD96661.1 - 6.2e-10 39.0 0.0 4.8e-09 36.1 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) zf-HC2 PF13490.1 EGD96661.1 - 0.11 12.4 0.4 8.4 6.4 0.1 2.6 2 0 0 2 2 2 0 Putative zinc-finger Taxilin PF09728.4 EGD96663.1 - 1.9e-103 345.8 50.1 1.9e-103 345.8 34.7 1.3 2 0 0 2 2 2 1 Myosin-like coiled-coil protein AAA_13 PF13166.1 EGD96663.1 - 0.025 13.0 36.6 0.18 10.2 9.5 2.2 2 0 0 2 2 2 0 AAA domain Laminin_I PF06008.9 EGD96663.1 - 0.72 9.1 36.4 0.099 11.9 8.6 2.8 1 1 1 2 2 2 0 Laminin Domain I DUF3584 PF12128.3 EGD96663.1 - 1.4 6.1 48.3 1.9 5.7 32.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF725 PF05267.7 EGD96663.1 - 1.9 8.3 9.4 0.14 12.0 2.3 2.2 2 2 0 2 2 2 0 Protein of unknown function (DUF725) TMF_TATA_bd PF12325.3 EGD96663.1 - 4.1 7.1 54.1 0.099 12.3 9.3 4.3 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.6 EGD96663.1 - 6.4 6.7 18.1 0.76 9.6 1.4 4.0 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 EGD96663.1 - 7.4 6.3 35.0 0.65 9.7 2.7 4.1 1 1 2 4 4 4 0 Laminin Domain II zf-C4H2 PF10146.4 EGD96663.1 - 8.4 6.3 35.2 0.058 13.4 6.2 3.1 2 1 1 3 3 3 0 Zinc finger-containing protein DUF3675 PF12428.3 EGD96663.1 - 10 6.4 10.2 2.7 8.2 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3675) NMO PF03060.10 EGD96664.1 - 8.9e-73 245.2 0.8 1e-72 245.0 0.5 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGD96664.1 - 8.3e-06 24.9 0.1 0.022 13.6 0.2 2.8 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGD96664.1 - 0.0024 16.8 2.7 0.0037 16.1 1.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ATP_synt_I PF03899.10 EGD96664.1 - 0.094 12.8 0.3 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 ATP synthase I chain DNA_pol_E_B PF04042.11 EGD96665.1 - 3.9e-38 130.8 0.0 9.8e-38 129.4 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Acetyltransf_3 PF13302.1 EGD96666.1 - 2.3e-29 102.4 0.0 1.4e-28 99.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGD96666.1 - 2.8e-05 24.0 0.2 0.62 9.9 0.0 3.1 2 1 1 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD96666.1 - 0.0006 19.5 0.1 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_4 PF13420.1 EGD96666.1 - 0.0011 18.9 0.0 0.01 15.7 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GlcNAc PF11397.3 EGD96666.1 - 0.098 11.7 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Ribosomal_L38e PF01781.13 EGD96667.1 - 1.2e-31 108.2 1.7 1.4e-31 108.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF1470 PF07336.6 EGD96668.1 - 0.0013 19.1 0.8 0.0014 18.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1470) Ish1 PF10281.4 EGD96668.1 - 0.0036 17.3 0.1 0.0056 16.7 0.0 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EGD96668.1 - 0.045 13.2 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 SAP domain SAM_2 PF07647.12 EGD96668.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) NTF2 PF02136.15 EGD96669.1 - 6.2e-09 36.2 0.3 2e-07 31.4 0.2 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EGD96669.1 - 0.0022 17.8 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 tRNA-synt_1g PF09334.6 EGD96670.1 - 5.6e-98 328.1 1.0 1e-84 284.5 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGD96670.1 - 3.7e-18 64.8 0.8 5.4e-12 44.5 0.0 3.8 2 2 2 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EGD96670.1 - 0.00031 19.9 0.1 0.033 13.2 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EGD96670.1 - 0.00084 19.1 0.0 0.0058 16.3 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA PALP PF00291.20 EGD96671.1 - 3.7e-54 184.0 0.1 1.3e-53 182.2 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PEP_mutase PF13714.1 EGD96671.1 - 0.062 12.5 0.1 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase AlaDh_PNT_C PF01262.16 EGD96671.1 - 0.096 12.2 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PPTA PF01239.17 EGD96672.1 - 1.7e-18 65.0 0.1 0.00015 20.9 0.0 3.7 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat Peptidase_M13_N PF05649.8 EGD96672.1 - 0.057 12.4 0.2 7.2 5.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M13 TPR_16 PF13432.1 EGD96672.1 - 0.28 11.8 5.7 8.9 7.1 0.2 3.3 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGD96672.1 - 0.81 10.5 3.6 1.2 10.0 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.21 EGD96673.1 - 1.1e-18 67.0 0.2 9.2e-18 64.0 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGD96673.1 - 1.4e-09 38.0 0.0 3.4e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EGD96673.1 - 0.0092 15.2 0.0 0.022 14.0 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature AA_permease PF00324.16 EGD96674.1 - 6.7e-53 179.7 32.9 8.2e-53 179.4 22.8 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 EGD96675.1 - 1.3e-82 277.4 34.1 1.6e-82 277.2 23.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3687 PF12459.3 EGD96675.1 - 0.19 11.0 3.0 0.78 9.0 2.1 2.1 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein LSM PF01423.17 EGD96676.1 - 1.1e-18 66.4 0.0 1.4e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 EGD96677.1 - 1.1e-22 79.5 0.0 1.5e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EGD96677.1 - 2e-21 75.4 0.1 7.2e-21 73.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 CPSase_L_D2 PF02786.12 EGD96679.1 - 1.4e-80 269.5 0.1 2.2e-80 268.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EGD96679.1 - 1.8e-66 223.3 0.0 2.9e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EGD96679.1 - 7e-36 122.6 0.1 1.5e-35 121.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGD96679.1 - 5.8e-31 106.6 0.0 1.9e-30 105.0 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EGD96679.1 - 2e-23 83.2 0.0 4e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EGD96679.1 - 2.2e-17 63.3 0.1 4.6e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EGD96679.1 - 3.4e-17 61.8 4.4 3.5e-17 61.7 2.0 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EGD96679.1 - 7.4e-17 61.0 0.0 2.6e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EGD96679.1 - 6.4e-10 38.5 3.5 3.6e-06 26.5 0.1 2.9 2 1 1 3 3 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EGD96679.1 - 2.9e-09 36.5 0.0 5.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EGD96679.1 - 1.2e-06 27.9 0.0 2.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EGD96679.1 - 2e-06 27.4 0.0 4.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EGD96679.1 - 0.00013 21.9 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 EGD96679.1 - 0.0024 17.0 0.0 1.4 8.0 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EGD96679.1 - 0.0039 17.4 0.2 0.066 13.5 0.1 2.9 2 1 1 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 EGD96679.1 - 0.015 14.6 0.0 0.065 12.5 0.1 2.0 2 0 0 2 2 2 0 HlyD family secretion protein DUF2118 PF09891.4 EGD96679.1 - 0.032 13.9 0.1 0.072 12.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF3572 PF12096.3 EGD96679.1 - 0.1 12.4 0.0 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) SUI1 PF01253.17 EGD96679.1 - 0.13 12.1 0.0 27 4.6 0.0 2.7 2 0 0 2 2 2 0 Translation initiation factor SUI1 Clathrin PF00637.15 EGD96680.1 - 2.6e-192 630.1 31.6 2.8e-34 117.7 0.4 7.4 6 1 1 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EGD96680.1 - 2.3e-28 97.8 0.2 8.9e-28 95.9 0.1 2.1 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EGD96680.1 - 9.6e-26 88.2 7.5 0.00019 21.4 0.0 7.7 7 0 0 7 7 7 6 Clathrin propeller repeat TPR_7 PF13176.1 EGD96680.1 - 0.0032 17.1 5.8 29 4.7 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Clathrin-link PF09268.5 EGD96680.1 - 0.0095 14.9 0.2 0.022 13.7 0.1 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_14 PF13428.1 EGD96680.1 - 0.043 14.4 7.0 44 5.0 0.0 7.5 12 0 0 12 12 12 0 Tetratricopeptide repeat Transformer PF06495.6 EGD96681.1 - 0.19 11.6 1.8 0.2 11.5 1.2 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein INSIG PF07281.7 EGD96682.1 - 6.1e-58 195.3 4.3 7.7e-58 195.0 3.0 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) DUF898 PF05987.8 EGD96682.1 - 0.092 11.6 2.5 0.2 10.5 1.6 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Plasmodium_Vir PF05795.6 EGD96683.1 - 1.4 8.0 9.3 0.57 9.3 1.3 2.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DEAD PF00270.24 EGD96684.1 - 8.4e-27 93.7 0.0 2.1e-12 46.8 0.0 3.2 2 1 1 3 3 3 3 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD96684.1 - 9.6e-15 54.2 0.0 1.8e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fungal_trans_2 PF11951.3 EGD96685.1 - 1e-05 24.3 0.0 7.5e-05 21.4 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.23 EGD96687.1 - 2.1e-110 369.9 0.0 2.7e-110 369.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD96687.1 - 4.4e-06 26.4 0.0 7.5e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD96687.1 - 0.00099 18.3 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Pro_isomerase PF00160.16 EGD96688.1 - 4e-47 160.3 0.7 5.2e-47 159.9 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.17 EGD96689.1 - 6.7e-22 77.9 0.1 8.5e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EGD96689.1 - 0.039 12.5 0.0 0.045 12.2 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) WD40 PF00400.27 EGD96690.1 - 9e-29 98.2 19.4 1.4e-07 31.0 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 EGD96690.1 - 8.7e-19 67.2 0.0 1.5e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Zw10 PF06248.8 EGD96691.1 - 2.5e-16 58.9 3.7 1.6e-15 56.3 2.4 2.1 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EGD96691.1 - 5.6e-06 25.7 2.3 6.2e-06 25.5 0.1 2.1 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Nop14 PF04147.7 EGD96691.1 - 6.3 4.5 21.8 0.014 13.3 8.1 1.5 2 0 0 2 2 2 0 Nop14-like family Peptidase_M16_C PF05193.16 EGD96692.1 - 2.7e-17 63.0 0.0 3.8e-14 52.7 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGD96692.1 - 5.3e-07 29.4 0.7 1.2e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RQC PF09382.5 EGD96692.1 - 0.023 14.3 0.1 0.37 10.5 0.0 2.8 4 0 0 4 4 4 0 RQC domain Ank_2 PF12796.2 EGD96693.1 - 1.3e-68 227.3 0.2 6.5e-17 61.6 0.0 4.9 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EGD96693.1 - 4.5e-47 155.5 6.6 0.00031 20.4 0.1 12.3 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.1 EGD96693.1 - 2.4e-46 155.3 0.4 3.1e-11 43.4 0.1 8.9 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD96693.1 - 4.9e-39 128.4 3.1 0.0042 17.1 0.0 12.2 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.1 EGD96693.1 - 5.4e-30 102.7 1.5 5.6e-09 35.9 0.0 9.0 2 2 8 10 10 10 9 Ankyrin repeats (many copies) NACHT PF05729.7 EGD96693.1 - 0.036 13.7 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 EGD96693.1 - 0.04 14.0 0.0 0.2 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF1843 PF08898.5 EGD96693.1 - 1.3 9.1 5.2 26 4.9 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Abhydrolase_6 PF12697.2 EGD96695.1 - 2e-10 40.9 1.2 3.9e-10 39.9 0.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD96695.1 - 1.6e-09 37.6 0.2 3.3e-09 36.6 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD96695.1 - 0.00037 20.1 0.4 0.00057 19.5 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD96695.1 - 0.036 13.2 0.2 7.6 5.6 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EGD96695.1 - 0.061 13.1 0.2 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 Putative lysophospholipase Fungal_trans PF04082.13 EGD96696.1 - 1.5e-19 69.9 0.2 2.9e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD96696.1 - 6.5e-09 35.5 11.9 1.3e-08 34.6 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EGD96697.1 - 5.9e-41 140.3 56.5 2.1e-40 138.5 36.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3482 PF11981.3 EGD96697.1 - 0.44 9.7 2.2 0.92 8.6 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Cu-oxidase_3 PF07732.10 EGD96698.1 - 1.6e-42 143.9 1.5 1.2e-41 141.1 0.3 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGD96698.1 - 3e-24 85.1 6.1 1.6e-17 63.3 0.6 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EGD96698.1 - 4.2e-15 55.9 0.0 2e-13 50.5 0.0 2.7 2 1 0 2 2 2 1 Multicopper oxidase Zn_clus PF00172.13 EGD96699.1 - 1.8e-06 27.7 9.8 1.8e-06 27.7 6.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EthD PF07110.6 EGD96700.1 - 1.6e-19 70.6 0.2 2.5e-19 69.9 0.2 1.3 1 0 0 1 1 1 1 EthD domain ketoacyl-synt PF00109.21 EGD96701.1 - 5e-63 212.9 0.3 5.7e-62 209.4 0.2 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGD96701.1 - 2.9e-46 158.2 0.0 3.7e-45 154.6 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGD96701.1 - 1.7e-31 108.5 0.6 7.6e-31 106.4 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EGD96701.1 - 4.5e-26 92.4 0.0 2.3e-25 90.1 0.0 2.3 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EGD96701.1 - 6.9e-16 58.2 4.3 2.8e-09 37.1 0.4 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EGD96701.1 - 1.7e-08 34.6 0.2 0.0001 22.2 0.0 2.9 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EGD96701.1 - 7.5e-07 28.3 0.1 1.6e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EGD96701.1 - 9.4e-07 28.6 0.0 0.035 13.8 0.0 2.9 2 0 0 2 2 2 2 Alpha/beta hydrolase family Histone PF00125.19 EGD96701.1 - 0.067 13.3 0.0 0.58 10.3 0.0 2.4 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF2048 PF09752.4 EGD96701.1 - 0.36 9.6 0.5 0.65 8.8 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Methyltransf_2 PF00891.13 EGD96702.1 - 6.1e-36 123.8 0.0 7.9e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGD96702.1 - 4.3e-05 24.0 0.0 8.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD96702.1 - 0.0026 18.1 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD96702.1 - 0.0044 16.7 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD96702.1 - 0.022 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M48 PF01435.13 EGD96703.1 - 1.4e-49 168.6 0.0 2.1e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.1 EGD96703.1 - 0.011 15.0 1.4 0.028 13.7 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Peptidase_M56 PF05569.6 EGD96703.1 - 0.021 13.8 1.8 0.097 11.6 0.3 2.3 2 1 0 2 2 2 0 BlaR1 peptidase M56 RNA_polI_A14 PF08203.6 EGD96704.1 - 0.0017 18.5 0.0 0.009 16.2 0.0 2.0 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 SDA1 PF05285.7 EGD96704.1 - 0.075 12.3 11.7 0.092 12.0 8.1 1.1 1 0 0 1 1 1 0 SDA1 Peptidase_S49_N PF08496.5 EGD96704.1 - 1.7 8.3 6.8 2.6 7.8 4.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ribosomal_L34 PF00468.12 EGD96705.1 - 1.2e-15 56.8 9.1 1.9e-15 56.2 6.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 GTP_EFTU PF00009.22 EGD96706.1 - 1.7e-38 131.9 0.0 2.7e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EGD96706.1 - 3.5e-36 123.1 0.1 7.3e-36 122.1 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EGD96706.1 - 1.2e-11 44.5 0.3 2.5e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGD96706.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGD96706.1 - 0.12 12.1 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 Dynamin family WD40 PF00400.27 EGD96707.1 - 1.2e-13 50.3 0.1 0.00017 21.3 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat HSA PF07529.8 EGD96708.1 - 2.2e-22 78.6 1.5 2.2e-22 78.6 1.1 3.1 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 EGD96708.1 - 4.4e-16 58.7 0.1 4.4e-16 58.7 0.1 2.8 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD96708.1 - 0.00019 21.3 0.1 0.00056 19.8 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain G-patch_2 PF12656.2 EGD96709.1 - 7.3e-29 99.4 0.0 3.5e-28 97.2 0.0 2.3 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 EGD96709.1 - 7.3e-05 22.4 0.5 0.00027 20.6 0.3 2.1 1 0 0 1 1 1 1 G-patch domain WD40 PF00400.27 EGD96710.1 - 1.8e-79 259.0 30.1 4.5e-09 35.8 0.2 12.8 13 2 0 13 13 13 11 WD domain, G-beta repeat Utp13 PF08625.6 EGD96710.1 - 4.3e-45 152.8 0.1 6.7e-45 152.1 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 EGD96710.1 - 3.5e-05 22.7 9.3 0.11 11.1 0.0 5.7 4 2 0 5 5 5 3 Nup133 N terminal like MMS1_N PF10433.4 EGD96710.1 - 0.00048 18.3 0.1 0.017 13.2 0.0 3.1 3 1 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Peptidase_S51 PF03575.12 EGD96711.1 - 0.33 10.7 2.4 0.73 9.5 1.6 1.5 1 0 0 1 1 1 0 Peptidase family S51 UCH PF00443.24 EGD96712.1 - 1.1e-21 77.2 0.0 3e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGD96712.1 - 7.3e-12 45.2 0.2 1.3e-11 44.4 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EGD96712.1 - 9.9e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TLD PF07534.11 EGD96713.1 - 2.6e-10 40.4 0.0 5.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 TLD Peptidase_C97 PF05903.9 EGD96714.1 - 0.0017 18.1 0.1 0.0024 17.6 0.1 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRRC37AB_C PF14914.1 EGD96714.1 - 0.0078 15.6 1.7 0.013 14.9 1.2 1.3 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain Arrestin_N PF00339.24 EGD96714.1 - 0.021 14.6 1.3 0.033 13.9 0.9 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain LRAT PF04970.8 EGD96714.1 - 0.064 13.2 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Vac_ImportDeg PF09783.4 EGD96714.1 - 0.068 12.6 2.9 1.6 8.1 1.1 2.1 1 1 1 2 2 2 0 Vacuolar import and degradation protein Proteasome PF00227.21 EGD96715.1 - 2.5e-29 101.9 0.0 2.8e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 EGD96716.1 - 2.2e-28 97.0 16.8 3.1e-07 30.0 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EGD96716.1 - 0.00097 17.3 2.2 1.6 6.7 0.1 3.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGD96716.1 - 0.0077 15.0 0.5 3.8 6.1 0.0 2.7 2 1 0 2 2 2 2 Nup133 N terminal like zf-RING_2 PF13639.1 EGD96717.1 - 7.9e-10 38.4 8.9 7.9e-10 38.4 6.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGD96717.1 - 5.9e-09 35.4 7.7 5.9e-09 35.4 5.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD96717.1 - 1.7e-08 34.3 9.3 1.7e-08 34.3 6.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD96717.1 - 2.6e-08 33.4 5.2 2.6e-08 33.4 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGD96717.1 - 2.5e-07 30.4 10.5 2.5e-07 30.4 7.3 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGD96717.1 - 1.7e-06 27.6 8.2 1.7e-06 27.6 5.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGD96717.1 - 3.5e-05 23.4 3.8 3.5e-05 23.4 2.7 1.9 2 0 0 2 2 2 1 RING-type zinc-finger DZR PF12773.2 EGD96717.1 - 0.12 12.1 14.0 2.5 7.9 0.8 2.9 2 1 0 2 2 2 0 Double zinc ribbon zf-Apc11 PF12861.2 EGD96717.1 - 0.75 9.6 9.7 0.051 13.4 2.8 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGD96717.1 - 0.87 9.7 12.0 0.18 11.9 5.0 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger Lin-8 PF03353.10 EGD96717.1 - 4 6.6 7.7 7.2 5.7 5.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-RING_6 PF14835.1 EGD96717.1 - 5.9 6.7 9.3 0.14 11.9 1.9 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein 2OG-FeII_Oxy_3 PF13640.1 EGD96718.1 - 0.0025 18.3 0.0 0.0048 17.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CHCH PF06747.8 EGD96719.1 - 3.8e-05 23.4 4.8 9.6e-05 22.1 3.1 1.8 1 1 1 2 2 2 1 CHCH domain DUF1903 PF08991.5 EGD96719.1 - 0.00056 20.0 1.9 0.00075 19.6 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) UPF0203 PF05254.7 EGD96719.1 - 0.0038 17.0 3.1 0.011 15.5 2.1 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EGD96719.1 - 0.3 10.8 4.7 0.95 9.2 0.4 2.5 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like NatB_MDM20 PF09797.4 EGD96720.1 - 2.8e-86 289.5 1.5 4.1e-86 288.9 1.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 EGD96720.1 - 2.9e-06 27.5 8.9 0.033 14.5 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD96720.1 - 0.00024 21.6 7.3 0.32 11.7 0.4 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Alpha-mann_mid PF09261.6 EGD96720.1 - 0.12 12.6 0.6 0.74 10.0 0.0 2.7 3 0 0 3 3 3 0 Alpha mannosidase, middle domain TPR_14 PF13428.1 EGD96720.1 - 0.3 11.8 9.1 48 5.0 0.2 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat Proteasome PF00227.21 EGD96721.1 - 6.8e-42 142.9 0.0 7.9e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 EGD96722.1 - 5.6e-25 87.0 1.1 3.4e-24 84.5 0.0 2.5 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EGD96722.1 - 5.7e-07 29.4 0.2 5.6e-06 26.3 0.0 2.7 3 0 0 3 3 3 1 UBX domain RBD PF02196.10 EGD96722.1 - 0.012 15.2 0.0 0.046 13.4 0.0 1.9 2 0 0 2 2 2 0 Raf-like Ras-binding domain Med12-LCEWAV PF12145.3 EGD96722.1 - 0.016 13.7 1.5 0.024 13.1 1.0 1.3 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Ribosomal_L36e PF01158.13 EGD96723.1 - 6.6e-38 128.6 7.3 7.5e-38 128.4 5.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.4 EGD96723.1 - 0.13 12.0 1.7 0.15 11.8 1.0 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 LemA PF04011.7 EGD96723.1 - 0.17 10.9 0.6 0.19 10.7 0.4 1.1 1 0 0 1 1 1 0 LemA family HATPase_c PF02518.21 EGD96724.1 - 3.8e-19 68.4 0.0 7.4e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGD96724.1 - 2.7e-13 49.8 0.4 6.3e-08 32.6 0.1 3.5 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EGD96724.1 - 0.00013 21.9 0.1 0.00013 21.9 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EGD96724.1 - 0.061 12.9 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase M20_dimer PF07687.9 EGD96725.1 - 4.9e-22 77.7 0.0 2.1e-21 75.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EGD96725.1 - 7.7e-18 64.6 2.8 3e-17 62.7 2.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EGD96725.1 - 0.00013 20.8 0.0 0.0011 17.8 0.0 2.3 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase DUF373 PF04123.8 EGD96725.1 - 0.046 12.7 0.4 0.076 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Glyco_hydro_47 PF01532.15 EGD96726.1 - 2e-159 531.0 0.0 2.4e-159 530.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA PF00004.24 EGD96727.1 - 5.3e-43 146.3 0.0 8.9e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGD96727.1 - 3.1e-07 30.5 0.0 5.7e-06 26.4 0.0 2.5 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.9 EGD96727.1 - 1.7e-06 27.8 0.0 4.2e-05 23.2 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGD96727.1 - 1.9e-06 27.8 0.0 6.6e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGD96727.1 - 2.4e-06 27.6 0.0 0.00088 19.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EGD96727.1 - 7.7e-06 25.1 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EGD96727.1 - 0.00032 19.6 0.0 0.00074 18.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EGD96727.1 - 0.00037 21.2 0.5 0.0014 19.4 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EGD96727.1 - 0.00045 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EGD96727.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD96727.1 - 0.0014 18.9 0.2 0.0074 16.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EGD96727.1 - 0.0015 17.3 0.0 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EGD96727.1 - 0.0016 18.2 0.0 0.0055 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGD96727.1 - 0.0031 16.9 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGD96727.1 - 0.004 16.3 0.0 0.0077 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EGD96727.1 - 0.005 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF4200 PF13863.1 EGD96727.1 - 0.0056 16.6 0.3 0.015 15.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_3 PF07726.6 EGD96727.1 - 0.007 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGD96727.1 - 0.0082 15.6 0.0 0.029 13.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EGD96727.1 - 0.0088 15.4 0.1 0.046 13.1 0.1 2.0 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGD96727.1 - 0.0099 16.0 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 EGD96727.1 - 0.019 14.5 0.1 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EGD96727.1 - 0.026 14.3 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EGD96727.1 - 0.026 14.4 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGD96727.1 - 0.028 13.5 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 KaiC Arch_ATPase PF01637.13 EGD96727.1 - 0.031 13.9 0.1 0.14 11.8 0.0 2.1 2 1 0 2 2 1 0 Archaeal ATPase UPF0079 PF02367.12 EGD96727.1 - 0.033 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EGD96727.1 - 0.036 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 EGD96727.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EGD96727.1 - 0.052 13.1 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.1 EGD96727.1 - 0.066 12.7 0.1 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EGD96727.1 - 0.083 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 EGD96727.1 - 0.16 12.2 3.0 2.7 8.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain IncA PF04156.9 EGD96727.1 - 0.17 11.4 1.8 0.33 10.5 1.2 1.3 1 0 0 1 1 1 0 IncA protein E1-E2_ATPase PF00122.15 EGD96728.1 - 6e-48 162.8 1.8 1.5e-47 161.6 1.3 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD96728.1 - 1.3e-43 148.5 4.0 1.3e-43 148.5 2.8 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD96728.1 - 9.8e-31 107.8 0.0 2.4e-30 106.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD96728.1 - 2.8e-18 65.6 0.0 6.1e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGD96728.1 - 4.5e-14 53.0 0.0 1.1e-13 51.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD96728.1 - 2.2e-12 46.2 0.0 4.7e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGD96728.1 - 0.00066 19.3 0.1 0.0019 17.8 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Enolase_C PF00113.17 EGD96730.1 - 6.1e-153 508.0 0.0 8e-153 507.6 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EGD96730.1 - 4.3e-57 191.7 0.4 7.1e-57 190.9 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 EGD96730.1 - 0.042 14.3 0.0 0.093 13.2 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain VSP PF03302.8 EGD96730.1 - 0.1 11.1 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein MR_MLE_C PF13378.1 EGD96730.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 Enolase C-terminal domain-like eIF3_subunit PF08597.5 EGD96731.1 - 8.7e-63 212.1 26.4 1e-62 211.8 18.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit TATR PF03430.8 EGD96731.1 - 4.5 5.7 16.3 0.41 9.2 7.4 1.7 2 0 0 2 2 2 0 Trans-activating transcriptional regulator UPF0029 PF01205.14 EGD96731.1 - 7.7 6.2 7.8 8.3 6.1 3.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein family UPF0029 14-3-3 PF00244.15 EGD96732.1 - 4.7e-114 379.3 3.0 6.1e-114 378.9 2.1 1.1 1 0 0 1 1 1 1 14-3-3 protein HisKA PF00512.20 EGD96732.1 - 0.07 13.1 0.4 12 5.9 0.0 2.9 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain TPR_7 PF13176.1 EGD96732.1 - 0.095 12.5 0.8 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4164 PF13747.1 EGD96732.1 - 0.16 12.1 2.1 0.77 9.9 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) TPR_12 PF13424.1 EGD96732.1 - 1.2 9.1 5.2 18 5.3 0.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short PF00106.20 EGD96733.1 - 1.6e-13 50.9 0.0 2.7e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD96733.1 - 0.00042 20.0 0.0 0.0007 19.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD96733.1 - 0.033 13.6 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family E1-E2_ATPase PF00122.15 EGD96734.1 - 5.7e-66 221.8 6.7 1e-63 214.5 4.8 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD96734.1 - 5.8e-46 156.3 7.8 5.8e-46 156.3 5.4 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD96734.1 - 5.7e-31 108.6 0.0 5.1e-30 105.4 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD96734.1 - 3.6e-20 71.2 0.0 1.3e-19 69.3 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGD96734.1 - 2.8e-19 68.8 0.0 6.1e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGD96734.1 - 5.5e-16 59.3 0.0 2e-15 57.4 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD96734.1 - 6e-08 32.5 1.6 9e-06 25.4 0.7 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGD96734.1 - 0.018 15.2 0.0 0.05 13.8 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Peptidase_S8 PF00082.17 EGD96735.1 - 5.7e-45 153.6 12.3 8.4e-45 153.0 8.5 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD96735.1 - 1.1e-16 61.0 0.3 2e-16 60.2 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 MBOAT_2 PF13813.1 EGD96737.1 - 2.2e-17 62.9 4.9 5.8e-17 61.5 3.4 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Macoilin PF09726.4 EGD96738.1 - 4.2 5.5 7.4 5.2 5.2 5.1 1.0 1 0 0 1 1 1 0 Transmembrane protein DnaJ PF00226.26 EGD96739.1 - 4.3e-19 68.0 3.3 7.1e-19 67.3 2.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2076 PF09849.4 EGD96739.1 - 0.00045 20.3 0.0 0.00055 20.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF456 PF04306.8 EGD96739.1 - 0.00066 19.7 0.5 0.00095 19.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) IFP_35_N PF07334.8 EGD96739.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF460 PF04312.8 EGD96739.1 - 0.088 12.3 0.4 0.16 11.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) DUF1183 PF06682.7 EGD96739.1 - 0.088 12.4 0.2 0.14 11.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Gly-zipper_OmpA PF13436.1 EGD96739.1 - 0.35 10.5 2.0 0.8 9.3 1.4 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 EGD96739.1 - 2.2 8.4 11.2 0.24 11.5 4.8 1.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide MFS_1 PF07690.11 EGD96741.1 - 5.7e-41 140.3 48.0 1.3e-40 139.2 33.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily EspB PF05802.6 EGD96741.1 - 0.056 12.3 1.0 0.093 11.6 0.7 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein PMM PF03332.8 EGD96742.1 - 1.2e-103 345.4 0.1 1.4e-103 345.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EGD96742.1 - 6.7e-06 25.8 0.0 2.3e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EGD96742.1 - 0.00079 18.5 0.1 0.0012 18.0 0.1 1.2 1 0 0 1 1 1 1 TMPIT-like protein DUF1640 PF07798.6 EGD96743.1 - 9.9e-64 214.6 4.9 1.2e-63 214.3 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) G-alpha PF00503.15 EGD96743.1 - 0.033 12.8 0.8 0.051 12.2 0.6 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Trypsin_2 PF13365.1 EGD96744.1 - 7.3e-16 58.2 0.0 1.3e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EGD96744.1 - 1.4e-05 24.8 0.0 2.9e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Trypsin Peptidase_C4 PF00863.14 EGD96744.1 - 0.00027 20.0 0.0 0.019 13.9 0.0 2.1 2 0 0 2 2 2 2 Peptidase family C4 Peptidase_S32 PF05579.8 EGD96744.1 - 0.044 12.7 0.0 0.73 8.7 0.0 2.0 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 DUF3812 PF12757.2 EGD96745.1 - 4.4e-31 107.4 3.1 4.4e-31 107.4 2.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3812) MFS_1 PF07690.11 EGD96746.1 - 4.4e-16 58.5 43.8 1.7e-14 53.3 30.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily HlyIII PF03006.15 EGD96746.1 - 0.019 14.3 15.6 0.013 14.9 1.1 3.5 1 1 3 4 4 4 0 Haemolysin-III related Sugar_tr PF00083.19 EGD96746.1 - 3.7 6.0 29.4 1.5e+02 0.6 20.4 2.6 1 1 0 1 1 1 0 Sugar (and other) transporter Pkinase PF00069.20 EGD96747.1 - 2e-67 227.0 0.0 2e-67 227.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96747.1 - 1.7e-41 142.0 0.0 2.5e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD96747.1 - 2.7e-10 39.7 0.0 2.8e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EGD96747.1 - 0.0018 17.4 0.4 0.015 14.3 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD96747.1 - 0.024 14.3 7.5 2 8.0 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 EGD96747.1 - 2 7.7 4.7 0.85 8.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Prenyltrans PF00432.16 EGD96748.1 - 1.1e-31 108.0 12.5 6.2e-08 32.0 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGD96748.1 - 1.8e-25 89.5 0.0 8.2e-19 68.0 0.0 3.8 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGD96748.1 - 4.1e-07 29.9 0.0 0.0017 18.3 0.0 3.7 2 1 2 4 4 4 2 Prenyltransferase-like Ilm1 PF10311.4 EGD96749.1 - 2.4e-20 72.6 0.0 8.9e-20 70.8 0.0 1.9 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 CFEM PF05730.6 EGD96751.1 - 9.3e-14 51.0 14.3 1.5e-13 50.2 9.9 1.4 1 0 0 1 1 1 1 CFEM domain MFS_1 PF07690.11 EGD96752.1 - 3.7e-18 65.3 31.6 8.9e-12 44.3 4.6 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.11 EGD96753.1 - 1.2e-10 40.6 40.3 1.2e-10 40.6 28.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGD96753.1 - 4.4e-08 32.7 7.2 4.4e-08 32.7 5.0 3.0 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 BcrAD_BadFG PF01869.15 EGD96754.1 - 2.1e-09 37.1 0.0 5e-09 35.8 0.0 1.7 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.1 EGD96754.1 - 7.4e-06 25.7 0.0 1.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 SIS domain SIS PF01380.17 EGD96754.1 - 1.7e-05 24.4 0.3 0.00012 21.6 0.0 2.4 2 0 0 2 2 2 1 SIS domain ADP_ribosyl_GH PF03747.9 EGD96755.1 - 5.7e-58 196.9 0.0 6.9e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF1772 PF08592.6 EGD96756.1 - 0.064 12.9 0.4 0.064 12.9 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) DnaJ PF00226.26 EGD96757.1 - 4.9e-12 45.4 0.4 1.7e-11 43.6 0.3 2.0 1 1 0 1 1 1 1 DnaJ domain PRA1 PF03208.14 EGD96758.1 - 1.2e-32 112.3 0.1 1.8e-32 111.7 0.1 1.2 1 0 0 1 1 1 1 PRA1 family protein TRAP_alpha PF03896.11 EGD96758.1 - 0.014 14.4 2.4 0.46 9.4 0.2 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Sarcoglycan_1 PF04790.8 EGD96758.1 - 0.31 10.1 1.1 0.49 9.5 0.7 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein SpoIIIAH PF12685.2 EGD96758.1 - 7 6.0 8.2 0.14 11.6 0.5 1.9 2 0 0 2 2 2 0 SpoIIIAH-like protein Frag1 PF10277.4 EGD96759.1 - 2.9e-37 128.2 12.3 3.4e-37 128.0 8.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4436 PF14494.1 EGD96759.1 - 0.029 13.6 1.4 0.049 12.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) DUF1980 PF09323.5 EGD96759.1 - 0.093 12.4 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Herpes_LMP1 PF05297.6 EGD96759.1 - 5.8 5.7 8.5 0.32 9.8 2.0 1.7 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) SNF2_N PF00176.18 EGD96763.1 - 4.6e-55 186.5 0.0 1.2e-54 185.1 0.0 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 EGD96763.1 - 2.1e-09 36.8 8.0 7.5e-09 35.1 5.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD96763.1 - 1.7e-08 34.1 9.5 4.4e-08 32.8 6.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGD96763.1 - 2.4e-07 30.6 10.1 6.6e-07 29.2 7.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD96763.1 - 4.8e-07 29.3 7.6 4.8e-07 29.3 5.3 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD96763.1 - 1.8e-05 24.7 6.1 5.5e-05 23.1 4.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGD96763.1 - 2.5e-05 23.9 7.9 6e-05 22.6 5.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.26 EGD96763.1 - 0.00032 20.5 0.0 0.00084 19.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 EGD96763.1 - 0.0018 18.1 7.7 0.0042 16.9 5.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD96763.1 - 0.0046 16.6 5.0 0.016 14.9 3.5 2.0 1 1 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.10 EGD96763.1 - 0.0089 15.8 0.0 0.04 13.7 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Baculo_IE-1 PF05290.6 EGD96763.1 - 0.13 11.9 2.7 0.39 10.4 1.8 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 EGD96763.1 - 0.17 11.4 7.4 0.44 10.1 5.1 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EGD96763.1 - 0.23 11.0 4.0 0.54 9.8 2.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Mito_carr PF00153.22 EGD96764.1 - 5.6e-67 221.5 0.6 9.3e-22 76.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1049 PF06305.6 EGD96764.1 - 0.031 13.7 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Ecm29 PF13001.2 EGD96765.1 - 1.5e-152 508.6 0.1 3.2e-151 504.2 0.0 3.1 3 1 0 3 3 3 1 Proteasome stabiliser HEAT_2 PF13646.1 EGD96765.1 - 4.1e-07 30.1 13.9 1.1 9.6 0.1 7.9 7 1 1 8 8 8 3 HEAT repeats HEAT PF02985.17 EGD96765.1 - 6.2e-07 28.9 1.9 1.3 9.3 0.0 9.3 12 0 0 12 12 12 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EGD96765.1 - 0.016 15.5 2.3 0.24 11.7 0.1 4.3 6 1 0 6 6 6 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGD96765.1 - 0.06 13.8 13.6 0.34 11.4 0.0 7.6 8 1 1 9 9 9 0 HEAT-like repeat Fungal_trans_2 PF11951.3 EGD96767.1 - 6.7e-22 77.6 1.5 1.7e-20 73.0 1.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain WW PF00397.21 EGD96768.1 - 5.3e-09 35.7 0.6 1.4e-08 34.4 0.4 1.8 1 0 0 1 1 1 1 WW domain Lipase_3 PF01764.20 EGD96769.1 - 7.3e-31 106.6 0.0 1.1e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 EGD96769.1 - 0.00066 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF2974 PF11187.3 EGD96769.1 - 0.046 13.0 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) GHMP_kinases_C PF08544.8 EGD96769.1 - 0.072 13.2 0.0 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 GHMP kinases C terminal WD40 PF00400.27 EGD96770.1 - 3.5e-23 80.5 9.6 7.5e-08 31.9 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Rax2 PF12768.2 EGD96770.1 - 0.0086 15.3 0.1 0.048 12.8 0.0 2.1 2 0 0 2 2 2 1 Cortical protein marker for cell polarity RRM_5 PF13893.1 EGD96771.1 - 2.5e-09 36.8 0.0 3.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD96771.1 - 2.5e-07 30.2 0.0 5.9e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD96771.1 - 8.9e-06 25.6 0.0 1.6e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2360 PF10152.4 EGD96771.1 - 0.16 12.2 1.0 0.19 11.9 0.7 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Autophagy_act_C PF03987.10 EGD96772.1 - 1e-09 38.4 0.1 6.2e-08 32.7 0.1 3.0 2 1 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Sulfatase PF00884.18 EGD96773.1 - 1.8e-77 260.5 0.0 2.3e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EGD96773.1 - 1.8e-05 23.3 0.0 2.4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 EGD96773.1 - 0.092 12.0 0.0 0.16 11.2 0.0 1.4 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EGD96773.1 - 0.14 11.5 0.0 2.1 7.6 0.0 2.4 2 1 0 2 2 2 0 Metalloenzyme superfamily MFS_1 PF07690.11 EGD96775.1 - 1.7e-32 112.5 67.4 7.2e-28 97.3 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD96775.1 - 6.2e-09 34.9 43.0 0.00027 19.6 13.2 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter Bac_rhodopsin PF01036.13 EGD96776.1 - 5.3e-36 123.9 20.3 6.1e-36 123.8 14.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein HSP20 PF00011.16 EGD96779.1 - 3.7e-18 65.2 0.1 2.7e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family TPP1 PF10341.4 EGD96779.1 - 0.042 13.8 0.0 0.092 12.7 0.0 1.7 1 1 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD Mif2_N PF15624.1 EGD96779.1 - 0.069 13.7 3.5 0.11 13.0 2.4 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Complex1_LYR PF05347.10 EGD96780.1 - 1.7e-17 62.9 1.7 2e-17 62.7 1.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGD96780.1 - 4.1e-15 55.7 1.5 4.9e-15 55.4 1.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like dDENN PF03455.14 EGD96780.1 - 0.073 13.1 0.6 0.1 12.7 0.4 1.2 1 0 0 1 1 1 0 dDENN domain Complex1_LYR_2 PF13233.1 EGD96780.1 - 0.089 13.2 0.2 0.11 13.0 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like FAA_hydrolase PF01557.13 EGD96781.1 - 1.3e-60 204.5 0.0 1.7e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Proteasome PF00227.21 EGD96782.1 - 8.8e-30 103.4 0.0 1.1e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HCNGP PF07818.8 EGD96783.1 - 9.3e-34 115.3 0.3 1.8e-33 114.4 0.2 1.5 1 0 0 1 1 1 1 HCNGP-like protein Ketoacyl-synt_C PF02801.17 EGD96783.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Proteasome PF00227.21 EGD96784.1 - 6.5e-32 110.3 0.1 1.5e-31 109.2 0.1 1.5 2 1 0 2 2 2 1 Proteasome subunit KH_1 PF00013.24 EGD96785.1 - 0.00035 20.1 1.2 0.0007 19.1 0.8 1.5 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.6 EGD96786.1 - 3.3e-145 484.4 0.1 3.9e-145 484.1 0.1 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins RhoGAP PF00620.22 EGD96787.1 - 2.1e-39 134.5 0.0 4.6e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EGD96787.1 - 4.6e-12 46.0 0.0 1.1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGD96787.1 - 1.2e-07 31.9 0.0 4.2e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain R_equi_Vir PF05526.6 EGD96787.1 - 0.0019 17.9 1.3 0.0069 16.0 0.9 2.0 1 0 0 1 1 1 1 Rhodococcus equi virulence-associated protein PH_8 PF15409.1 EGD96787.1 - 0.0097 15.9 0.0 0.034 14.1 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Dpoe2NT PF12213.3 EGD96787.1 - 0.057 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal DivIC PF04977.10 EGD96787.1 - 1.3 8.5 5.6 11 5.6 3.7 2.6 2 0 0 2 2 2 0 Septum formation initiator Erv26 PF04148.8 EGD96788.1 - 2.2e-89 298.4 0.3 2.6e-89 298.1 0.2 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 QueT PF06177.6 EGD96788.1 - 0.03 14.2 3.1 0.064 13.2 2.1 1.5 1 0 0 1 1 1 0 QueT transporter WBS_methylT PF12589.3 EGD96789.1 - 8.6e-18 64.6 3.5 1.5e-17 63.8 2.5 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EGD96789.1 - 2.1e-11 44.1 0.0 3.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD96789.1 - 9.2e-08 32.3 0.0 2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD96789.1 - 2.2e-06 27.3 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD96789.1 - 2.5e-05 24.6 0.0 6.1e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD96789.1 - 4.5e-05 24.0 0.0 0.0001 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD96789.1 - 6.3e-05 22.7 0.0 9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD96789.1 - 0.0003 20.7 0.0 0.00064 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGD96789.1 - 0.0004 19.9 0.0 0.00074 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EGD96789.1 - 0.002 17.2 0.0 0.018 14.1 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EGD96789.1 - 0.035 13.1 0.0 0.43 9.6 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase ACT_7 PF13840.1 EGD96789.1 - 0.16 11.4 0.1 0.34 10.4 0.1 1.5 1 0 0 1 1 1 0 ACT domain Iso_dh PF00180.15 EGD96790.1 - 1.1e-83 281.0 0.0 1.4e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NdhL PF10716.4 EGD96791.1 - 0.097 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit Peptidase_S46 PF10459.4 EGD96791.1 - 0.098 11.0 2.3 0.12 10.7 1.6 1.0 1 0 0 1 1 1 0 Peptidase S46 IFT20 PF14931.1 EGD96791.1 - 0.17 11.8 9.4 0.23 11.3 6.5 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 PspB PF06667.7 EGD96791.1 - 0.81 9.6 7.7 0.19 11.6 3.2 1.6 1 1 0 1 1 1 0 Phage shock protein B Proteasome PF00227.21 EGD96793.1 - 2.2e-45 154.3 0.3 4.1e-32 111.0 0.0 2.7 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 EGD96793.1 - 8.6e-12 44.1 0.9 1e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nucleoplasmin PF03066.10 EGD96793.1 - 0.36 10.3 12.7 0.55 9.7 8.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin Med17 PF10156.4 EGD96793.1 - 1.7 6.8 8.4 2.1 6.5 5.9 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex PBP1_TM PF14812.1 EGD96793.1 - 1.9 8.8 13.8 3.6 7.9 9.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 EGD96793.1 - 5.2 5.6 20.0 7.9 5.0 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DMRL_synthase PF00885.14 EGD96794.1 - 8e-45 152.0 0.1 1.5e-44 151.1 0.1 1.4 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Copper-fist PF00649.13 EGD96795.1 - 1.6e-22 78.4 1.5 1.6e-22 78.4 1.0 2.5 2 1 1 3 3 3 1 Copper fist DNA binding domain Zn_clus PF00172.13 EGD96796.1 - 2.2e-10 40.2 9.6 3.3e-10 39.6 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGD96796.1 - 0.016 14.1 0.2 0.03 13.1 0.2 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain F-box-like PF12937.2 EGD96797.1 - 1.4e-05 24.6 2.6 6.1e-05 22.6 1.8 2.1 1 1 0 1 1 1 1 F-box-like DUF812 PF05667.6 EGD96797.1 - 0.098 11.1 0.4 0.13 10.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Pyr_redox_3 PF13738.1 EGD96798.1 - 6.1e-23 81.9 0.0 1.1e-22 81.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGD96798.1 - 1.7e-13 49.6 0.0 1.3e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EGD96798.1 - 1e-10 41.0 0.0 2.5e-07 29.9 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGD96798.1 - 1.2e-09 38.3 0.0 3.1e-06 27.2 0.0 3.0 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD96798.1 - 5e-06 25.7 0.1 2.6e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EGD96798.1 - 8.8e-06 25.5 0.0 0.0077 16.0 0.0 2.7 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGD96798.1 - 0.00014 21.8 0.6 0.00062 19.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGD96798.1 - 0.00018 20.5 0.1 0.018 13.9 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.22 EGD96798.1 - 0.0018 18.6 1.9 0.54 10.7 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EGD96798.1 - 0.0028 17.8 0.0 0.43 10.8 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EGD96798.1 - 0.005 15.7 0.9 0.39 9.5 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EGD96798.1 - 0.01 14.7 0.8 0.094 11.6 0.0 2.8 3 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGD96798.1 - 0.025 13.6 0.6 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EGD96798.1 - 0.026 13.0 2.6 0.23 9.8 0.1 2.9 3 0 0 3 3 3 0 HI0933-like protein DUF4147 PF13660.1 EGD96798.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Arf PF00025.16 EGD96800.1 - 1.7e-73 245.5 0.1 2e-73 245.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGD96800.1 - 7.3e-12 44.9 0.0 8.2e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGD96800.1 - 1.3e-11 44.0 0.0 1.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGD96800.1 - 2.2e-11 43.3 0.0 2.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGD96800.1 - 5.3e-11 41.8 1.8 1.7e-07 30.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EGD96800.1 - 1.6e-06 28.5 0.0 2.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGD96800.1 - 7.4e-05 22.6 0.1 0.00031 20.6 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EGD96800.1 - 0.027 13.5 0.3 0.042 12.9 0.0 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase WD40 PF00400.27 EGD96801.1 - 2.2e-20 71.7 13.7 3.6e-06 26.6 0.4 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EGD96801.1 - 0.00047 19.9 0.0 0.012 15.3 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EGD96801.1 - 0.0015 16.4 0.0 0.0029 15.5 0.0 1.4 1 1 0 1 1 1 1 IKI3 family Vps16_N PF04841.8 EGD96801.1 - 0.055 11.9 0.0 3.3 6.1 0.0 2.1 1 1 0 2 2 2 0 Vps16, N-terminal region Cytochrom_D1 PF02239.11 EGD96801.1 - 0.067 11.4 0.0 0.11 10.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Lgl_C PF08596.5 EGD96801.1 - 0.087 11.2 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal DUF1273 PF06908.6 EGD96801.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) DUF2422 PF10337.4 EGD96802.1 - 9.4e-41 140.0 5.4 9.4e-41 140.0 3.8 3.5 3 2 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EGD96802.1 - 1.7e-10 40.9 11.3 1.7e-10 40.9 7.9 3.3 3 2 0 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EGD96802.1 - 1.5e-08 34.5 0.1 1.1e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EGD96802.1 - 0.23 10.0 14.7 0.4 9.2 6.8 3.1 2 2 0 2 2 2 0 Aluminium activated malate transporter Zds_C PF08632.5 EGD96803.1 - 9.3e-31 104.9 3.7 2e-30 103.9 1.2 2.2 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF500 PF04366.7 EGD96804.1 - 4.2e-45 152.2 0.1 2.2e-44 149.9 0.2 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EGD96804.1 - 9e-13 47.4 0.1 4e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EGD96804.1 - 2.6e-12 46.1 0.0 4.4e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGD96804.1 - 3.6e-12 45.5 0.0 8.2e-12 44.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Miro PF08477.8 EGD96805.1 - 7.3e-37 126.4 0.0 3.2e-19 69.5 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EGD96805.1 - 6.9e-35 118.6 0.0 1.4e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EGD96805.1 - 2e-31 107.1 0.2 3.3e-31 106.3 0.2 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EGD96805.1 - 4.2e-24 84.7 0.0 7.4e-14 51.4 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EGD96805.1 - 8.6e-10 38.5 0.0 0.00016 21.6 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EGD96805.1 - 4.6e-08 33.0 0.1 0.0016 18.5 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGD96805.1 - 6.3e-08 31.8 0.5 0.021 14.6 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EGD96805.1 - 8e-07 27.9 3.9 0.01 15.0 0.1 3.1 3 0 0 3 3 2 2 EF hand AAA_29 PF13555.1 EGD96805.1 - 1.4e-05 24.5 0.1 0.01 15.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EGD96805.1 - 1.5e-05 24.8 1.2 0.74 9.6 0.0 4.0 5 0 0 5 5 4 2 Dynamin family AAA_16 PF13191.1 EGD96805.1 - 2.1e-05 24.5 3.8 0.016 15.2 0.1 2.7 3 1 0 3 3 2 2 AAA ATPase domain EF-hand_10 PF14788.1 EGD96805.1 - 5.6e-05 22.7 1.5 0.01 15.4 0.1 2.4 2 0 0 2 2 2 1 EF hand AAA_22 PF13401.1 EGD96805.1 - 0.00011 22.3 0.0 0.82 9.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain EF-hand_8 PF13833.1 EGD96805.1 - 0.0004 19.9 0.2 0.22 11.1 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair MobB PF03205.9 EGD96805.1 - 0.00064 19.4 0.1 0.26 11.0 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EGD96805.1 - 0.0021 18.0 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EGD96805.1 - 0.0022 17.5 0.2 0.088 12.3 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EGD96805.1 - 0.0023 17.3 0.1 2.1 7.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain EF-hand_5 PF13202.1 EGD96805.1 - 0.0031 16.7 6.3 0.12 11.8 0.2 3.0 3 0 0 3 3 2 2 EF hand NACHT PF05729.7 EGD96805.1 - 0.0038 16.9 0.1 3.3 7.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain GTP_EFTU PF00009.22 EGD96805.1 - 0.004 16.6 0.0 3.1 7.1 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EGD96805.1 - 0.0048 16.7 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGD96805.1 - 0.0068 16.5 0.0 0.87 9.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 EGD96805.1 - 0.0097 16.2 0.0 5.9 7.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 EGD96805.1 - 0.0099 15.3 0.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 EGD96805.1 - 0.011 16.5 0.0 7.3 7.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGD96805.1 - 0.013 14.9 0.2 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.13 EGD96805.1 - 0.017 14.1 0.0 0.82 8.6 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_18 PF13238.1 EGD96805.1 - 0.02 15.1 0.6 11 6.4 0.1 2.9 2 2 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EGD96805.1 - 0.021 14.3 1.9 4.2 6.8 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EGD96805.1 - 0.022 14.3 0.1 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGD96805.1 - 0.046 12.9 0.1 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SMC_N PF02463.14 EGD96805.1 - 0.055 12.7 0.3 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF815 PF05673.8 EGD96805.1 - 0.057 12.3 0.1 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.14 EGD96805.1 - 0.07 12.5 0.8 1.7 8.0 0.0 3.2 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EGD96805.1 - 0.08 13.2 0.1 14 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EGD96805.1 - 0.084 12.6 0.3 22 4.7 0.0 2.9 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 EGD96805.1 - 0.087 11.5 0.6 2.5 6.7 0.0 2.2 2 0 0 2 2 2 0 ArgK protein MCM PF00493.18 EGD96805.1 - 0.12 11.1 0.0 2.8 6.6 0.0 2.2 2 0 0 2 2 2 0 MCM2/3/5 family AAA PF00004.24 EGD96805.1 - 0.13 12.4 0.5 13 5.9 0.1 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EGD96805.1 - 0.22 10.6 0.0 2.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Activator-TraM PF11657.3 EGD96806.1 - 0.074 12.5 0.3 0.098 12.1 0.2 1.2 1 1 0 1 1 1 0 Transcriptional activator TraM Fib_alpha PF08702.5 EGD96806.1 - 0.096 12.8 1.2 0.11 12.5 0.9 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Synaptobrevin PF00957.16 EGD96806.1 - 0.12 12.0 4.3 2.2 7.9 0.4 2.1 1 1 1 2 2 2 0 Synaptobrevin Smr PF01713.16 EGD96807.1 - 1.2e-10 41.4 1.7 1.5e-10 41.1 0.1 2.0 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.5 EGD96807.1 - 2.6e-10 40.1 4.1 2.6e-10 40.1 2.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) CUE PF02845.11 EGD96807.1 - 2.8e-08 33.0 0.1 1.7e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 CUE domain UBA PF00627.26 EGD96807.1 - 0.0082 15.9 0.1 0.088 12.6 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain TMF_DNA_bd PF12329.3 EGD96807.1 - 0.17 11.7 2.7 0.39 10.5 0.1 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding SelR PF01641.13 EGD96808.1 - 1.8e-50 169.7 0.1 2.1e-50 169.5 0.1 1.0 1 0 0 1 1 1 1 SelR domain NinF PF05810.7 EGD96808.1 - 0.014 15.1 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 NinF protein GFA PF04828.9 EGD96808.1 - 0.024 14.5 0.7 2.4 8.1 0.0 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2296 PF10058.4 EGD96808.1 - 0.046 13.4 0.2 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) TF_Zn_Ribbon PF08271.7 EGD96808.1 - 0.076 12.3 0.5 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding Yippee-Mis18 PF03226.9 EGD96808.1 - 0.078 13.0 1.4 0.75 9.8 1.0 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 EGD96808.1 - 0.17 11.7 2.7 9.5 6.1 0.1 2.4 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EGD96808.1 - 0.81 9.5 4.4 10 5.9 0.0 2.7 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.1 EGD96808.1 - 0.91 9.8 4.1 8.8 6.6 0.1 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-Mss51 PF13824.1 EGD96808.1 - 1.1 9.1 5.1 3.7 7.4 0.2 3.0 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 ArfGap PF01412.13 EGD96809.1 - 4.3e-40 136.1 2.6 6.8e-40 135.5 1.8 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GPI-anchored PF10342.4 EGD96810.1 - 9.2e-12 45.2 0.0 1.6e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DJ-1_PfpI PF01965.19 EGD96811.1 - 1.4e-07 31.0 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EGD96811.1 - 3.9e-07 29.4 0.0 5.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DUF3328 PF11807.3 EGD96812.1 - 0.014 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) ARID PF01388.16 EGD96813.1 - 4.4e-06 26.4 0.0 6.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Amidase PF01425.16 EGD96814.1 - 1e-66 225.6 0.1 6.5e-65 219.7 0.0 2.0 1 1 0 1 1 1 1 Amidase PEX11 PF05648.9 EGD96815.1 - 5.7e-70 235.0 0.2 6.4e-70 234.8 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sugar_tr PF00083.19 EGD96816.1 - 3.4e-31 108.3 29.1 1.6e-20 73.1 6.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGD96816.1 - 1.2e-18 67.0 63.5 8.9e-18 64.1 27.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PEPCK_ATP PF01293.15 EGD96817.1 - 4.8e-217 721.0 0.0 5.8e-217 720.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 EGD96817.1 - 0.09 12.6 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGD96817.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Telomere_Sde2 PF13019.1 EGD96818.1 - 0.027 14.1 0.4 0.039 13.6 0.2 1.4 1 0 0 1 1 1 0 Telomere stability and silencing Aminotran_1_2 PF00155.16 EGD96819.1 - 1.5e-38 132.7 0.0 2e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.4 EGD96820.1 - 3.2e-54 182.9 0.5 6.4e-54 182.0 0.3 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EGD96820.1 - 8.7e-12 45.2 0.0 1.9e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 EGD96820.1 - 0.04 13.7 3.1 0.12 12.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MIS13 PF08202.6 EGD96821.1 - 1.7e-43 148.7 4.7 1.7e-43 148.7 3.3 2.8 2 1 0 2 2 2 1 Mis12-Mtw1 protein family DivIC PF04977.10 EGD96821.1 - 0.02 14.3 0.1 0.055 12.9 0.0 1.8 1 0 0 1 1 1 0 Septum formation initiator Sugar_tr PF00083.19 EGD96822.1 - 3e-83 279.9 26.9 7.6e-83 278.5 18.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD96822.1 - 1.2e-32 113.0 43.5 1.8e-23 82.8 7.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 EGD96823.1 - 9.7e-56 188.9 0.8 3.2e-55 187.2 0.6 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Acyl_transf_1 PF00698.16 EGD96823.1 - 9.9e-48 163.0 0.0 1.9e-47 162.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.15 EGD96823.1 - 1.7e-39 135.4 0.0 2.9e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 EGD96823.1 - 8.8e-39 133.0 0.0 4.2e-37 127.5 0.0 2.6 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.21 EGD96823.1 - 1.4e-38 132.8 0.0 2.2e-28 99.4 0.0 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EGD96823.1 - 8.6e-30 103.9 0.0 2e-25 89.5 0.0 2.3 1 1 1 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EGD96823.1 - 1.4e-29 102.3 0.0 4.5e-29 100.7 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EGD96823.1 - 3.7e-29 101.8 0.0 9.2e-27 93.9 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EGD96823.1 - 7.6e-26 90.5 0.0 2.8e-25 88.6 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EGD96823.1 - 1e-18 67.3 0.1 1.9e-09 37.6 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EGD96823.1 - 3.5e-18 65.8 0.0 8.7e-17 61.4 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD96823.1 - 3.6e-11 43.0 0.0 1.3e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD96823.1 - 1.1e-09 38.9 0.0 6.1e-09 36.4 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD96823.1 - 2.4e-09 37.5 0.0 1.4e-08 35.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.16 EGD96823.1 - 4.2e-08 32.9 0.0 8e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 EGD96823.1 - 7.2e-08 32.1 0.0 5.8e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain HxxPF_rpt PF13745.1 EGD96823.1 - 3.3e-07 30.5 0.0 1.1e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain Ubie_methyltran PF01209.13 EGD96823.1 - 2.4e-05 23.5 0.0 6.9e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EGD96823.1 - 0.0026 17.2 0.0 0.0075 15.7 0.0 1.7 2 0 0 2 2 1 1 Putative methyltransferase Post_transc_reg PF13797.1 EGD96823.1 - 0.1 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Post-transcriptional regulator UvdE PF03851.9 EGD96824.1 - 3.4e-109 364.1 0.0 4.3e-109 363.8 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE ADH_zinc_N PF00107.21 EGD96826.1 - 5.1e-10 39.0 0.0 1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD96826.1 - 2.8e-07 30.2 1.8 8.3e-07 28.7 1.1 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.16 EGD96826.1 - 0.076 12.9 0.4 0.15 11.9 0.3 1.5 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit Pkinase PF00069.20 EGD96827.1 - 3.6e-64 216.4 0.0 4.4e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96827.1 - 2.5e-30 105.3 0.0 4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD96827.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-UBR PF02207.15 EGD96828.1 - 1.5e-16 59.8 3.9 1.5e-16 59.8 2.7 3.6 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.18 EGD96829.1 - 9.3e-135 448.6 0.0 1.4e-134 448.0 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EGD96829.1 - 1.9e-30 105.9 30.6 5e-30 104.5 21.2 1.7 1 0 0 1 1 1 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EGD96829.1 - 4.8e-18 65.8 0.1 1.1e-17 64.5 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGD96829.1 - 1.2e-07 31.1 0.1 7.3e-06 25.2 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGD96829.1 - 3.3e-06 26.8 0.0 6.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EGD96829.1 - 0.003 17.0 0.2 0.051 13.0 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EGD96829.1 - 0.0056 16.2 0.0 0.052 13.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) VHS PF00790.14 EGD96831.1 - 1.1e-29 102.8 0.1 6.4e-29 100.3 0.0 2.1 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EGD96831.1 - 2.1e-25 88.6 1.3 6.3e-25 87.0 0.9 1.8 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 EGD96831.1 - 1.5e-11 44.6 0.2 1.5e-11 44.6 0.1 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain DUF367 PF04034.8 EGD96834.1 - 2.4e-30 104.7 0.2 2.5e-23 82.0 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF367) RLI PF04068.10 EGD96834.1 - 2.5e-09 36.5 0.4 4.1e-09 35.8 0.2 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Treacle PF03546.9 EGD96834.1 - 0.004 15.9 3.9 0.004 15.9 2.7 1.5 1 1 0 1 1 1 1 Treacher Collins syndrome protein Treacle Peptidase_C37 PF05416.7 EGD96834.1 - 0.01 14.1 3.6 0.015 13.6 2.5 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF1293 PF06950.6 EGD96834.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1293) Daxx PF03344.10 EGD96834.1 - 1.6 7.1 12.1 2.1 6.7 8.4 1.2 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 EGD96834.1 - 3 6.7 12.6 4.2 6.3 8.7 1.2 1 0 0 1 1 1 0 BUD22 zf-H2C2 PF09337.5 EGD96835.1 - 3.2e-21 74.4 4.1 3.2e-21 74.4 2.8 1.9 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Acetyltransf_4 PF13420.1 EGD96835.1 - 0.0015 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD96835.1 - 0.003 17.5 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EGD96835.1 - 0.15 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cpn60_TCP1 PF00118.19 EGD96836.1 - 2.8e-100 336.2 7.0 1.1e-71 241.9 2.7 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family HSDR_N_2 PF13588.1 EGD96836.1 - 0.1 12.4 0.1 0.48 10.2 0.1 2.1 3 0 0 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) Peptidase_C14 PF00656.17 EGD96837.1 - 7.5e-69 232.1 0.0 9.3e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EGD96837.1 - 0.93 9.3 0.0 0.93 9.3 0.0 2.8 5 0 0 5 5 5 0 Raptor N-terminal CASPase like domain DUF605 PF04652.11 EGD96837.1 - 4 6.7 21.0 6.2 6.0 14.6 1.4 1 0 0 1 1 1 0 Vta1 like Sulfotransfer_3 PF13469.1 EGD96838.1 - 0.0019 19.1 0.5 0.0084 17.0 0.2 1.9 1 1 0 1 1 1 1 Sulfotransferase family LRR_6 PF13516.1 EGD96839.1 - 0.0016 18.3 8.1 10 6.5 0.0 6.0 6 0 0 6 6 6 1 Leucine Rich repeat F-box-like PF12937.2 EGD96839.1 - 0.0021 17.7 0.2 0.0072 16.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGD96839.1 - 0.028 14.0 11.1 4.9 6.8 0.0 4.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Deltaretro_Tax PF05599.6 EGD96839.1 - 0.039 14.2 1.1 0.097 12.9 0.8 1.7 1 0 0 1 1 1 0 Deltaretrovirus Tax protein LRR_1 PF00560.28 EGD96839.1 - 2.7 8.3 13.4 18 5.8 0.0 5.8 7 0 0 7 7 7 0 Leucine Rich Repeat Ribosomal_S26e PF01283.14 EGD96840.1 - 3.9e-50 168.8 8.2 4.8e-50 168.5 5.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 EGD96840.1 - 0.034 14.4 0.2 6.5 7.1 0.0 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain CBS PF00571.23 EGD96841.1 - 3.6e-41 138.6 6.9 1.1e-10 41.0 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EGD96841.1 - 2.4e-10 39.9 0.0 1e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 PB1 domain CW_binding_2 PF04122.7 EGD96841.1 - 0.06 13.5 1.9 0.18 12.0 0.2 2.6 3 1 0 3 3 3 0 Putative cell wall binding repeat 2 HEAT PF02985.17 EGD96842.1 - 1e-21 75.0 7.9 0.0045 16.9 0.0 11.3 12 0 0 12 12 12 5 HEAT repeat HEAT_2 PF13646.1 EGD96842.1 - 7.6e-21 74.1 8.9 4.7e-06 26.7 0.1 8.3 6 2 5 11 11 11 8 HEAT repeats HEAT_EZ PF13513.1 EGD96842.1 - 1e-16 60.8 15.4 7.3e-05 23.1 0.1 9.9 9 2 2 11 11 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGD96842.1 - 1.3e-09 38.3 0.0 0.083 13.2 0.0 5.9 3 2 2 6 6 6 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EGD96842.1 - 4.4e-07 28.9 0.1 0.013 14.2 0.0 4.7 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal RIX1 PF08167.7 EGD96842.1 - 2.3e-06 27.3 0.0 0.0089 15.7 0.0 4.6 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis Arm PF00514.18 EGD96842.1 - 1.6e-05 24.5 1.3 2.6 7.9 0.0 5.8 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EGD96842.1 - 2.9e-05 23.5 0.1 0.13 11.5 0.0 5.1 4 1 1 5 5 5 1 CLASP N terminal Proteasom_PSMB PF10508.4 EGD96842.1 - 0.00026 19.4 0.4 0.0011 17.4 0.0 2.3 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit DUF3385 PF11865.3 EGD96842.1 - 0.00038 20.4 1.2 9 6.2 0.0 4.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.15 EGD96842.1 - 0.00039 18.8 1.1 0.0094 14.3 0.1 3.4 3 1 1 4 4 4 1 Adaptin N terminal region Cnd1 PF12717.2 EGD96842.1 - 0.0023 17.8 0.2 0.33 10.7 0.0 4.0 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 EGD96842.1 - 0.0025 17.7 0.1 0.031 14.1 0.0 3.0 3 0 0 3 3 2 1 Importin-beta N-terminal domain V-ATPase_H_N PF03224.9 EGD96842.1 - 0.0075 15.4 0.8 0.18 10.9 0.0 3.2 3 1 0 3 3 3 1 V-ATPase subunit H DUF4042 PF13251.1 EGD96842.1 - 0.014 14.8 4.5 15 5.0 0.0 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) Aconitase PF00330.15 EGD96843.1 - 2.4e-156 520.8 0.0 1.1e-155 518.6 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGD96843.1 - 3.2e-41 140.5 0.0 5e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2408 PF10303.4 EGD96844.1 - 1.2e-56 190.5 0.1 5.5e-31 107.4 0.0 5.1 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) CARD PF00619.16 EGD96844.1 - 0.025 14.3 0.0 0.084 12.7 0.0 1.9 1 0 0 1 1 1 0 Caspase recruitment domain DUF3941 PF13081.1 EGD96844.1 - 0.093 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3941) Baculo_PEP_C PF04513.7 EGD96844.1 - 0.11 12.3 0.6 0.71 9.6 0.0 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_60s PF00428.14 EGD96845.1 - 6e-20 71.4 7.4 8.1e-20 71.0 5.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein PQ-loop PF04193.9 EGD96846.1 - 3e-40 135.5 4.6 2.2e-20 71.9 0.0 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF3796 PF12676.2 EGD96846.1 - 0.028 14.6 1.6 0.034 14.3 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) BCD PF15461.1 EGD96846.1 - 0.73 9.1 5.8 0.72 9.2 1.5 2.3 1 1 1 2 2 2 0 Beta-carotene 15,15'-dioxygenase DUF202 PF02656.10 EGD96846.1 - 8.2 6.7 7.0 27 5.0 0.0 3.4 4 1 0 4 4 4 0 Domain of unknown function (DUF202) Tcf25 PF04910.9 EGD96847.1 - 2.7e-88 296.3 0.2 4.3e-88 295.6 0.1 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF1754 PF08555.5 EGD96847.1 - 0.0077 16.8 3.3 0.0077 16.8 2.3 2.3 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) PP2C PF00481.16 EGD96848.1 - 1e-40 139.7 0.0 1.7e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EGD96848.1 - 0.00018 20.9 0.0 0.0004 19.8 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EGD96848.1 - 0.014 15.0 0.0 0.45 10.1 0.0 2.7 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) 60KD_IMP PF02096.15 EGD96849.1 - 5.6e-19 68.5 0.5 7e-19 68.2 0.3 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Antimicrobial19 PF08225.6 EGD96849.1 - 0.12 11.7 1.9 1.3 8.4 0.1 2.3 2 0 0 2 2 2 0 Pseudin antimicrobial peptide FA_desaturase PF00487.19 EGD96849.1 - 1.1 8.6 4.0 0.52 9.7 0.4 1.9 2 0 0 2 2 2 0 Fatty acid desaturase Methyltransf_23 PF13489.1 EGD96853.1 - 3.5e-17 62.5 0.0 5.1e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD96853.1 - 3.5e-06 27.5 0.0 7.3e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD96853.1 - 3.3e-05 24.2 0.0 0.0001 22.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD96853.1 - 3.7e-05 23.3 0.0 0.0001 21.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGD96853.1 - 0.0001 21.3 0.0 0.00024 20.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EGD96853.1 - 0.00025 21.4 0.0 0.00078 19.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD96853.1 - 0.00074 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGD96853.1 - 0.0013 19.1 0.0 0.01 16.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGD96853.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EGD96853.1 - 0.0047 16.0 0.0 0.0072 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EGD96853.1 - 0.0069 15.6 0.0 0.017 14.3 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_16 PF10294.4 EGD96853.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 EGD96853.1 - 0.02 14.8 0.0 0.033 14.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EGD96853.1 - 0.069 12.2 0.0 0.4 9.7 0.0 2.1 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EGD96853.1 - 0.081 11.9 0.0 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase WD40 PF00400.27 EGD96854.1 - 1.5e-15 56.3 3.3 1.1e-07 31.4 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EGD96854.1 - 2.2e-05 24.2 0.0 0.27 10.9 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGD96854.1 - 0.0061 14.9 0.0 0.011 14.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain RNA_pol_Rpb1_1 PF04997.7 EGD96855.1 - 1.9e-117 392.3 0.0 2.9e-117 391.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EGD96855.1 - 8.6e-76 254.8 0.0 1.9e-75 253.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGD96855.1 - 2.8e-68 229.0 0.0 6.3e-68 227.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EGD96855.1 - 7.2e-64 214.9 1.2 1.6e-63 213.8 0.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_4 PF05000.12 EGD96855.1 - 5.5e-38 129.0 0.2 1.1e-37 128.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.7 EGD96855.1 - 7.7e-37 126.0 10.3 9.6e-35 119.2 5.1 3.1 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.13 EGD96855.1 - 6e-28 97.5 0.0 1.4e-26 93.0 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_R PF05001.8 EGD96855.1 - 2.1e-10 39.7 196.9 0.029 14.4 7.1 14.9 12 2 2 15 15 15 11 RNA polymerase Rpb1 C-terminal repeat DUF3620 PF12281.3 EGD96856.1 - 8.4 6.0 8.7 0.52 9.9 2.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3620) Thg1C PF14413.1 EGD96857.1 - 5.7e-52 174.5 2.1 8.1e-52 174.0 1.5 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EGD96857.1 - 2.2e-49 166.5 0.0 3.4e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase fn3 PF00041.16 EGD96858.1 - 0.00061 19.8 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Leu_zip PF15294.1 EGD96858.1 - 0.034 13.2 27.5 0.05 12.6 19.1 1.2 1 0 0 1 1 1 0 Leucine zipper Reo_sigmaC PF04582.7 EGD96858.1 - 0.062 12.4 0.6 0.1 11.7 0.4 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein GAS PF13851.1 EGD96858.1 - 2.1 7.5 42.0 2.1 7.4 11.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding LNS2 PF08235.8 EGD96859.1 - 3.1e-70 234.7 0.0 5e-70 234.1 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EGD96859.1 - 9.9e-41 137.8 0.0 3.1e-40 136.2 0.0 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EGD96859.1 - 0.022 14.1 0.0 0.22 10.8 0.0 2.5 3 0 0 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) TFIID-31kDa PF02291.10 EGD96860.1 - 2.1e-29 101.9 0.0 8.8e-23 80.4 0.0 3.0 2 1 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit Cmc1 PF08583.5 EGD96861.1 - 1.9e-14 53.1 0.6 1.9e-14 53.1 0.4 1.8 2 1 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like Utp11 PF03998.8 EGD96862.1 - 2.9e-54 184.4 29.8 4e-54 184.0 20.7 1.2 1 0 0 1 1 1 1 Utp11 protein Histidinol_dh PF00815.15 EGD96863.1 - 8.3e-179 594.5 6.0 1.3e-178 593.8 4.2 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EGD96863.1 - 4.1e-25 87.1 0.1 8.5e-25 86.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EGD96863.1 - 1.9e-11 44.0 0.2 7.7e-11 42.1 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EGD96863.1 - 0.18 11.7 1.8 0.19 11.7 0.2 1.8 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Glyco_hydro_47 PF01532.15 EGD96865.1 - 1.5e-138 462.2 0.0 1.7e-138 462.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 VIT1 PF01988.14 EGD96866.1 - 0.0014 18.1 1.3 0.0024 17.3 0.9 1.3 1 0 0 1 1 1 1 VIT family Acetyltransf_3 PF13302.1 EGD96867.1 - 2.7e-18 66.4 0.0 6.5e-18 65.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD96867.1 - 2.6e-11 43.3 0.1 4.5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGD96867.1 - 0.00017 21.2 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EGD96867.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGD96867.1 - 0.087 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 EGD96868.1 - 4.8e-39 134.0 47.0 6.5e-39 133.6 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD96868.1 - 4.5e-22 78.0 41.0 9.5e-22 76.9 28.4 1.5 1 1 0 1 1 1 1 Amino acid permease YlaH PF14036.1 EGD96868.1 - 0.0018 18.2 2.9 0.0018 18.2 2.0 2.3 2 0 0 2 2 2 1 YlaH-like protein CBM_19 PF03427.8 EGD96868.1 - 0.068 12.9 0.6 0.2 11.4 0.4 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Acetyltransf_1 PF00583.19 EGD96871.1 - 8.8e-09 35.2 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD96871.1 - 2.6e-07 30.7 0.0 4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD96871.1 - 6.9e-06 26.1 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD96871.1 - 2e-05 24.2 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EGD96871.1 - 0.00046 20.0 0.2 0.1 12.4 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain CDC45 PF02724.9 EGD96872.1 - 4.9e-232 771.3 0.0 1e-231 770.3 0.0 1.9 1 1 0 1 1 1 1 CDC45-like protein PA14 PF07691.7 EGD96872.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 PA14 domain BUD22 PF09073.5 EGD96872.1 - 0.23 10.4 31.6 0.2 10.6 4.9 2.1 2 0 0 2 2 2 0 BUD22 DDRGK PF09756.4 EGD96872.1 - 0.45 9.8 13.3 0.86 8.9 9.2 1.4 1 0 0 1 1 1 0 DDRGK domain DUF3513 PF12026.3 EGD96872.1 - 0.86 9.1 4.2 1.7 8.1 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) FAM60A PF15396.1 EGD96872.1 - 4.1 7.1 8.6 0.13 11.9 1.2 1.8 2 0 0 2 2 2 0 Protein Family FAM60A Peptidase_C13 PF01650.13 EGD96873.1 - 4.1e-41 140.9 0.0 6.6e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family F-box-like PF12937.2 EGD96874.1 - 5.6e-07 29.1 0.3 1.2e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD96874.1 - 1.4e-06 27.8 0.6 1.4e-06 27.8 0.4 2.7 3 0 0 3 3 3 1 F-box domain Mito_fiss_reg PF05308.6 EGD96874.1 - 1.7 7.9 12.9 0.052 12.9 0.3 3.0 3 0 0 3 3 3 0 Mitochondrial fission regulator DUF1014 PF06244.7 EGD96875.1 - 5.6e-24 84.6 15.4 2.4e-23 82.6 10.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Toprim_4 PF13662.1 EGD96875.1 - 0.072 13.1 0.0 0.072 13.1 0.0 2.0 2 0 0 2 2 2 0 Toprim domain WD40 PF00400.27 EGD96876.1 - 6.8e-25 86.0 17.3 1.2e-08 34.4 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Abhydrolase_6 PF12697.2 EGD96877.1 - 7.7e-32 111.0 0.5 9.6e-32 110.6 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD96877.1 - 1.8e-08 34.2 0.3 3.4e-08 33.3 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EGD96878.1 - 2e-35 122.1 12.1 2e-34 118.8 7.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD96878.1 - 3.3e-10 39.1 1.9 6.6e-10 38.1 1.3 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter FGase PF05013.7 EGD96879.1 - 0.076 12.8 0.1 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase zf-DHHC PF01529.15 EGD96880.1 - 6.6e-41 139.5 8.3 1.7e-40 138.2 5.7 1.7 1 0 0 1 1 1 1 DHHC palmitoyltransferase UQ_con PF00179.21 EGD96881.1 - 4.5e-22 77.9 0.0 6.8e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGD96881.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain DUF1180 PF06679.7 EGD96881.1 - 0.016 15.1 0.3 0.032 14.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Rubredoxin PF00301.15 EGD96881.1 - 0.075 12.9 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Rubredoxin B-block_TFIIIC PF04182.7 EGD96882.1 - 5.2e-21 74.2 0.1 1.2e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 EGD96882.1 - 0.0057 16.2 2.1 0.012 15.2 0.1 2.7 2 0 0 2 2 2 1 MarR family RNA_pol_Rpc34 PF05158.7 EGD96882.1 - 0.17 11.0 0.0 2.6 7.1 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpc34 subunit Corona_M PF01635.13 EGD96883.1 - 0.88 8.4 5.8 0.29 10.0 1.8 1.8 1 1 0 1 1 1 0 Coronavirus M matrix/glycoprotein Fmp27 PF10344.4 EGD96884.1 - 9.5e-174 579.4 0.0 5.9e-173 576.8 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EGD96884.1 - 1.3e-153 512.2 0.0 3.3e-153 510.8 0.0 1.8 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EGD96884.1 - 1.6e-127 425.8 5.5 3.3e-127 424.7 3.8 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EGD96884.1 - 3.2e-52 176.5 0.0 8.4e-52 175.2 0.0 1.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EGD96884.1 - 2.8e-51 173.3 0.0 7.7e-51 171.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EGD96884.1 - 1.1e-26 93.2 0.0 4e-26 91.4 0.0 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain RNA_pol_Rpc4 PF05132.9 EGD96886.1 - 1.3e-29 102.7 0.0 1.3e-29 102.7 0.0 2.6 2 1 0 2 2 2 1 RNA polymerase III RPC4 HTH_32 PF13565.1 EGD96887.1 - 5.9e-07 30.1 6.6 6.1e-06 26.9 0.0 4.3 4 0 0 4 4 4 1 Homeodomain-like domain Pkinase PF00069.20 EGD96887.1 - 1.3e-06 27.7 0.0 0.00013 21.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain HTH_33 PF13592.1 EGD96887.1 - 0.00016 21.1 0.0 0.00042 19.7 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix Pkinase_Tyr PF07714.12 EGD96887.1 - 0.00062 18.9 0.2 0.032 13.3 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Zn_clus PF00172.13 EGD96888.1 - 0.00066 19.5 12.6 0.0014 18.5 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EGD96888.1 - 0.054 12.7 0.6 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 Histone chaperone domain CHZ DUF4349 PF14257.1 EGD96888.1 - 0.078 12.1 0.0 0.078 12.1 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4349) Cyclin_N PF00134.18 EGD96891.1 - 2.5e-43 146.6 0.4 5.3e-43 145.6 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGD96891.1 - 1.7e-21 76.3 3.3 5.3e-21 74.7 0.0 3.1 2 1 1 3 3 3 2 Cyclin, C-terminal domain DcpS_C PF11969.3 EGD96892.1 - 5e-15 55.7 1.9 3.1e-14 53.2 1.3 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EGD96892.1 - 7.7e-13 48.8 0.9 2.4e-12 47.2 0.6 1.8 1 1 0 1 1 1 1 HIT domain 2-Hacid_dh_C PF02826.14 EGD96893.1 - 8.5e-55 184.6 0.0 1.1e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD96893.1 - 6.4e-18 64.5 0.0 7.9e-18 64.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGD96893.1 - 2.6e-07 30.6 0.0 4.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EGD96893.1 - 0.0015 19.0 0.0 0.006 17.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EGD96893.1 - 0.0018 18.6 0.0 0.0037 17.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RRM_1 PF00076.17 EGD96895.1 - 1.9e-15 56.2 0.0 3.8e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD96895.1 - 3.3e-14 52.5 0.0 5.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD96895.1 - 5e-06 26.2 0.0 8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRP7 PF12923.2 EGD96895.1 - 0.13 12.3 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Sec2p PF06428.6 EGD96896.1 - 6.8e-10 38.7 12.9 6.8e-10 38.7 9.0 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p ATG16 PF08614.6 EGD96896.1 - 0.0014 18.4 9.1 0.0014 18.4 6.3 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) HSBP1 PF06825.7 EGD96896.1 - 0.006 16.1 2.1 0.13 11.9 0.3 2.4 2 0 0 2 2 2 1 Heat shock factor binding protein 1 FlhC PF05280.6 EGD96896.1 - 0.23 10.9 2.8 1 8.8 0.3 2.3 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) Phage_int_SAM_5 PF13102.1 EGD96896.1 - 0.33 10.9 6.1 0.3 11.1 0.3 2.2 2 0 0 2 2 2 0 Phage integrase SAM-like domain ECSIT PF06239.6 EGD96896.1 - 0.45 9.3 2.8 0.91 8.3 2.0 1.5 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway IncA PF04156.9 EGD96896.1 - 0.72 9.4 21.1 0.24 10.9 5.1 2.4 2 0 0 2 2 2 0 IncA protein Jnk-SapK_ap_N PF09744.4 EGD96896.1 - 3.1 7.7 13.3 2.5 8.0 5.3 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF2458 PF10454.4 EGD96896.1 - 5 6.9 9.7 0.27 11.1 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2458) Miff PF05644.6 EGD96896.1 - 5 6.6 15.9 2.3 7.8 8.9 1.7 1 1 1 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff Ribosomal_L32e PF01655.13 EGD96897.1 - 3.6e-48 162.1 1.3 4.6e-48 161.8 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 PseudoU_synth_2 PF00849.17 EGD96898.1 - 2.3e-24 86.1 0.0 4e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Glyco_tran_WecB PF03808.8 EGD96898.1 - 0.099 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family S4 PF01479.20 EGD96898.1 - 0.16 11.4 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 S4 domain 4HBT PF03061.17 EGD96899.1 - 1.1e-08 35.0 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EGD96899.1 - 0.00065 18.7 0.3 0.001 18.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.1 EGD96899.1 - 0.0099 16.3 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily CTDII PF01556.13 EGD96900.1 - 1.9e-23 82.1 0.2 1.6e-18 66.3 0.0 2.8 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EGD96900.1 - 1.6e-22 79.0 4.3 3.1e-22 78.0 3.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGD96900.1 - 3.1e-13 49.5 18.8 5.6e-13 48.7 13.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGD96900.1 - 0.033 13.8 5.7 0.9 9.2 0.5 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family YcfA PF07927.7 EGD96900.1 - 0.095 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 YcfA-like protein Malate_DH PF12434.3 EGD96900.1 - 0.17 11.5 0.5 0.38 10.4 0.4 1.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Cytochrom_c3_2 PF14537.1 EGD96900.1 - 0.64 10.3 5.5 1.4 9.3 3.7 1.7 1 1 0 1 1 1 0 Cytochrome c3 tRNA-synt_1c PF00749.16 EGD96901.1 - 4e-96 321.3 0.0 7.4e-96 320.5 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain MAP65_ASE1 PF03999.7 EGD96902.1 - 5.6e-76 256.4 5.0 5.6e-76 256.4 3.4 2.9 2 1 1 3 3 3 2 Microtubule associated protein (MAP65/ASE1 family) Seryl_tRNA_N PF02403.17 EGD96902.1 - 3.5 7.6 17.6 4.9 7.2 0.1 4.6 4 1 1 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Spectrin PF00435.16 EGD96902.1 - 4.2 7.6 11.9 1.7 8.9 0.3 3.9 3 1 1 4 4 4 0 Spectrin repeat TMF_TATA_bd PF12325.3 EGD96902.1 - 8.2 6.1 19.7 3.8 7.2 3.2 3.9 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Pkinase PF00069.20 EGD96903.1 - 1.5e-20 73.4 0.0 1.8e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96903.1 - 8.8e-18 64.3 0.0 1.6e-17 63.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD96903.1 - 0.00043 19.3 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGD96903.1 - 0.034 13.7 0.0 0.091 12.3 0.0 1.5 1 1 1 2 2 2 0 Choline/ethanolamine kinase JAB PF01398.16 EGD96904.1 - 3.9e-27 94.2 0.0 6.6e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EGD96904.1 - 2.8e-06 26.8 0.0 7.8e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain T2SM PF04612.7 EGD96905.1 - 0.04 13.7 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF1510 PF07423.6 EGD96905.1 - 0.05 12.9 0.0 0.06 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3301 PF11743.3 EGD96905.1 - 0.28 10.7 1.3 0.37 10.3 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3301) CRCB PF02537.10 EGD96906.1 - 2.2e-33 114.6 22.3 4.1e-21 75.0 4.1 3.9 4 0 0 4 4 4 3 CrcB-like protein UPRTase PF14681.1 EGD96907.1 - 7.2e-70 234.4 0.0 8.3e-70 234.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EGD96907.1 - 3.6e-07 29.9 0.0 1.1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Fungal_trans PF04082.13 EGD96909.1 - 6.8e-20 71.0 2.3 1.2e-19 70.2 1.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EGD96909.1 - 3.8e-07 30.0 14.2 0.00011 22.3 4.0 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EGD96909.1 - 0.0008 19.6 16.7 0.2 12.1 5.5 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type Mucin PF01456.12 EGD96909.1 - 0.0026 17.5 9.3 0.0081 15.9 6.4 1.8 1 0 0 1 1 1 1 Mucin-like glycoprotein zf-C2H2_4 PF13894.1 EGD96909.1 - 6.1 7.4 29.6 0.041 14.2 4.9 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger RasGEF PF00617.14 EGD96910.1 - 9.4e-64 214.5 0.0 1.7e-63 213.7 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGD96910.1 - 3.6e-25 88.0 0.1 7.8e-25 86.9 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EGD96910.1 - 1.4e-13 49.9 0.1 2.6e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD96910.1 - 3.6e-11 42.4 0.2 7.8e-11 41.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGD96910.1 - 4.3e-10 38.9 0.1 1e-09 37.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EGD96910.1 - 0.00091 19.0 0.0 0.0027 17.5 0.0 1.8 1 0 0 1 1 1 1 WW domain RHH_1 PF01402.16 EGD96910.1 - 0.26 11.2 2.0 0.4 10.6 0.1 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Arylsulfotran_2 PF14269.1 EGD96911.1 - 1.3e-111 372.5 0.4 1.9e-111 372.0 0.3 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EGD96911.1 - 1.1e-16 60.3 0.1 1.8e-15 56.4 0.1 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Pkinase PF00069.20 EGD96912.1 - 1.1e-35 123.0 0.0 1.4e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96912.1 - 7.6e-11 41.5 0.0 4.3e-09 35.8 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGD96912.1 - 0.038 12.7 0.1 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SPC25 PF06703.6 EGD96913.1 - 1.4 8.4 8.4 0.58 9.7 0.0 3.0 2 1 1 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) SIS PF01380.17 EGD96914.1 - 9.7e-50 167.5 0.1 6e-30 103.5 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EGD96914.1 - 3.8e-30 104.8 0.0 1.3e-19 70.1 0.0 2.5 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGD96914.1 - 7.8e-20 71.1 0.0 1.7e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EGD96914.1 - 1.9e-12 46.9 0.0 4.4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EGD96914.1 - 6.6e-08 31.5 0.0 1.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EGD96914.1 - 0.0026 17.4 0.0 0.35 10.5 0.0 2.6 2 0 0 2 2 2 1 SIS domain N-SET PF11764.3 EGD96915.1 - 3e-48 163.8 0.4 3e-48 163.8 0.3 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EGD96915.1 - 1.3e-25 88.4 0.3 2.4e-25 87.5 0.2 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EGD96915.1 - 1.5e-23 83.8 0.3 1.5e-23 83.8 0.2 2.9 3 1 0 3 3 3 1 SET domain RRM_1 PF00076.17 EGD96915.1 - 0.00014 21.4 0.0 0.00032 20.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD96915.1 - 0.18 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Trm112p PF03966.11 EGD96916.1 - 4.8e-15 55.6 0.1 6e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein DUF1451 PF07295.6 EGD96916.1 - 0.27 10.9 1.0 0.59 9.9 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) TF_Zn_Ribbon PF08271.7 EGD96916.1 - 0.64 9.3 2.9 0.36 10.1 0.3 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding Rad60-SLD PF11976.3 EGD96917.1 - 8.3e-25 86.2 0.9 4.1e-20 71.2 0.4 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGD96917.1 - 0.0016 17.8 0.3 0.09 12.1 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin family LSM PF01423.17 EGD96918.1 - 1.9e-18 65.7 0.0 2.2e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGD96918.1 - 0.0051 16.7 0.1 0.0058 16.5 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1106 PF06523.6 EGD96918.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) IF-2B PF01008.12 EGD96919.1 - 4.4e-70 235.8 0.7 5.2e-70 235.6 0.5 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family COG5 PF10392.4 EGD96920.1 - 0.035 14.0 0.1 0.047 13.6 0.1 1.2 1 1 0 1 1 1 0 Golgi transport complex subunit 5 AphA_like PF14557.1 EGD96920.1 - 0.15 11.5 0.8 0.17 11.3 0.5 1.1 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator DUF4238 PF14022.1 EGD96920.1 - 0.53 9.5 3.4 0.64 9.2 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) DUF4446 PF14584.1 EGD96920.1 - 2.7 7.8 4.7 0.82 9.4 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) IncA PF04156.9 EGD96920.1 - 2.7 7.5 8.5 3.2 7.3 5.9 1.2 1 0 0 1 1 1 0 IncA protein RP-C_C PF11800.3 EGD96920.1 - 2.9 7.5 5.5 3 7.4 3.8 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Vfa1 PF08432.5 EGD96920.1 - 5 7.1 12.4 5.6 6.9 8.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MbeB_N PF04837.7 EGD96920.1 - 5.2 7.2 6.8 2.1 8.4 0.4 2.3 2 0 0 2 2 2 0 MbeB-like, N-term conserved region XhlA PF10779.4 EGD96920.1 - 9.4 6.2 10.0 30 4.6 7.0 1.9 1 1 0 1 1 1 0 Haemolysin XhlA Pkinase PF00069.20 EGD96921.1 - 1.8e-15 56.8 0.0 4.1e-15 55.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96921.1 - 1.5e-11 43.9 0.0 3.2e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD96921.1 - 4.4e-05 22.5 0.0 5.9e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like GST_C PF00043.20 EGD96922.1 - 1.1e-14 54.1 0.2 2.1e-14 53.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGD96922.1 - 1.6e-12 47.4 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD96922.1 - 9.8e-10 38.4 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD96922.1 - 6.1e-09 35.7 0.0 2e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD96922.1 - 1.8e-08 34.1 0.1 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD96922.1 - 7.6e-06 26.3 0.4 1.1e-05 25.8 0.3 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EGD96922.1 - 0.022 15.1 0.0 0.048 14.0 0.0 1.6 1 1 0 1 1 1 0 MetRS-N binding domain RAMP4 PF06624.7 EGD96924.1 - 0.0013 18.2 0.1 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Adaptin_N PF01602.15 EGD96925.1 - 1.1e-78 264.8 0.0 2.4e-78 263.7 0.0 1.5 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EGD96925.1 - 0.0093 15.9 0.4 22 5.4 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EGD96925.1 - 0.086 12.6 2.5 0.61 9.9 0.1 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF4604 PF15377.1 EGD96925.1 - 0.63 10.2 22.2 0.34 11.1 12.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) TPR_14 PF13428.1 EGD96926.1 - 1.7e-07 31.2 1.8 0.075 13.6 0.0 4.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD96926.1 - 2e-07 30.5 1.1 0.00033 20.2 0.2 4.2 3 1 2 5 5 5 2 TPR repeat TPR_19 PF14559.1 EGD96926.1 - 3.4e-06 27.2 0.3 0.21 11.9 0.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGD96926.1 - 1.8e-05 24.5 0.0 0.094 12.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGD96926.1 - 6.9e-05 22.4 1.3 0.027 14.3 0.0 4.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGD96926.1 - 0.00018 21.0 0.1 0.017 14.8 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD96926.1 - 0.00061 20.3 3.4 1.9 9.2 0.0 4.6 2 1 3 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD96926.1 - 0.0019 18.0 1.3 3.1 7.7 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGD96926.1 - 0.031 13.9 0.0 0.41 10.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD96926.1 - 0.032 14.7 0.1 55 4.5 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 EGD96926.1 - 0.039 14.2 0.8 10 6.4 0.0 2.7 2 1 0 3 3 3 0 Bacterial transcriptional activator domain DUF3366 PF11846.3 EGD96926.1 - 0.053 13.3 0.0 5 6.9 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF3366) PPR_3 PF13812.1 EGD96926.1 - 0.077 13.3 0.0 0.32 11.3 0.0 2.1 2 0 0 2 2 1 0 Pentatricopeptide repeat domain Nucleoplasmin PF03066.10 EGD96927.1 - 4.5 6.7 13.4 12 5.4 9.3 1.6 1 0 0 1 1 1 0 Nucleoplasmin DUF940 PF06082.6 EGD96927.1 - 5.4 5.4 5.2 8.3 4.8 3.6 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Kinesin PF00225.18 EGD96929.1 - 5.5e-97 324.4 0.1 1e-96 323.5 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain DUF3899 PF13038.1 EGD96929.1 - 0.038 14.1 0.6 0.087 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) MoCF_biosynth PF00994.19 EGD96929.1 - 0.077 12.3 0.0 0.36 10.2 0.0 2.1 2 0 0 2 2 2 0 Probable molybdopterin binding domain Ank_2 PF12796.2 EGD96930.1 - 1.4e-107 352.2 12.5 5.2e-21 74.7 0.2 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EGD96930.1 - 1.1e-71 233.1 9.7 8.7e-09 34.7 0.0 12.1 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 EGD96930.1 - 5e-56 186.1 6.4 1.1e-09 38.5 0.1 9.7 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD96930.1 - 1.3e-54 176.6 4.1 7.8e-06 25.6 0.0 12.1 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.1 EGD96930.1 - 1.5e-47 158.5 8.0 3.7e-09 36.5 0.0 8.4 2 2 6 9 9 9 8 Ankyrin repeats (many copies) F-box-like PF12937.2 EGD96930.1 - 0.03 14.0 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 F-box-like gag-asp_proteas PF13975.1 EGD96930.1 - 0.12 12.2 0.0 0.51 10.1 0.0 2.2 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease NOGCT PF08155.6 EGD96932.1 - 0.0031 17.1 0.2 0.0076 15.9 0.1 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain DAGAT PF03982.8 EGD96933.1 - 3.3e-91 305.0 0.0 4.1e-91 304.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 EGD96933.1 - 0.042 13.4 3.7 0.093 12.3 2.6 1.5 1 0 0 1 1 1 0 Rer1 family G-patch PF01585.18 EGD96935.1 - 0.00048 19.8 0.0 0.016 14.9 0.0 2.6 2 0 0 2 2 2 1 G-patch domain CRT10 PF08728.5 EGD96935.1 - 0.6 8.0 5.9 0.69 7.8 4.1 1.1 1 0 0 1 1 1 0 CRT10 Asp-B-Hydro_N PF05279.6 EGD96935.1 - 0.78 9.5 22.7 1.1 9.0 15.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MIP-T3 PF10243.4 EGD96935.1 - 0.78 8.1 43.2 1.1 7.5 30.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Med19 PF10278.4 EGD96935.1 - 3.8 7.1 37.1 5.9 6.5 6.6 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 FCH PF00611.18 EGD96936.1 - 0.013 15.6 3.0 0.05 13.7 2.1 2.0 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Prominin PF05478.6 EGD96936.1 - 0.027 12.0 2.0 0.031 11.8 1.4 1.0 1 0 0 1 1 1 0 Prominin DUF1104 PF06518.6 EGD96936.1 - 0.043 13.9 0.9 0.043 13.9 0.6 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1104) Phage_GP20 PF06810.6 EGD96936.1 - 0.085 12.2 5.5 0.13 11.6 3.8 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 IncA PF04156.9 EGD96936.1 - 0.09 12.3 6.9 0.13 11.8 4.8 1.3 1 0 0 1 1 1 0 IncA protein DUF812 PF05667.6 EGD96936.1 - 0.3 9.5 10.2 0.34 9.3 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FliG_M PF14841.1 EGD96936.1 - 0.33 10.9 2.7 0.61 10.1 1.0 2.0 1 1 2 3 3 3 0 FliG middle domain Syja_N PF02383.13 EGD96937.1 - 1.1e-82 277.4 0.0 1.5e-82 276.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EGD96937.1 - 6.4e-14 52.4 0.5 4.3e-13 49.7 0.3 2.2 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 EGD96938.1 - 4e-63 212.9 0.0 4.8e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96938.1 - 7.5e-35 120.2 0.0 1.1e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD96938.1 - 0.099 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like IGR PF09597.5 EGD96939.1 - 2.1e-19 69.1 0.8 3.9e-19 68.3 0.6 1.5 1 0 0 1 1 1 1 IGR protein motif p450 PF00067.17 EGD96940.1 - 6.4e-69 232.6 0.0 8.3e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 K-box PF01486.12 EGD96940.1 - 0.069 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 K-box region Pkinase PF00069.20 EGD96941.1 - 8.6e-69 231.5 0.0 1.2e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96941.1 - 5e-36 124.1 0.0 6.7e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGD96941.1 - 4.7e-16 58.6 0.2 1.2e-15 57.3 0.1 1.8 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EGD96941.1 - 8.9e-07 28.1 0.0 2.4e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGD96941.1 - 0.0085 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EGD96941.1 - 0.01 14.7 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase PI3_PI4_kinase PF00454.22 EGD96942.1 - 1.6e-35 122.7 0.0 1.1e-34 119.9 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EGD96942.1 - 6.3e-24 84.1 0.1 1.4e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase PF00069.20 EGD96943.1 - 7.5e-22 77.7 0.0 1.3e-21 76.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96943.1 - 2.3e-05 23.5 0.0 4.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGD96943.1 - 0.018 13.8 0.3 0.025 13.4 0.2 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EGD96943.1 - 0.03 13.3 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ArfGap PF01412.13 EGD96945.1 - 8e-33 112.6 2.7 1e-32 112.3 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EGD96945.1 - 1.9e-12 47.2 0.1 5.7e-12 45.7 0.1 1.9 1 0 0 1 1 1 1 PH domain bact-PGI_C PF10432.4 EGD96945.1 - 0.038 13.6 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region LSM PF01423.17 EGD96947.1 - 1.1e-19 69.7 0.1 1.3e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ank_2 PF12796.2 EGD96948.1 - 2.4e-98 322.6 1.6 8.8e-16 58.0 0.0 7.0 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EGD96948.1 - 1.9e-51 169.3 11.4 4.7e-09 35.6 0.0 11.7 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 EGD96948.1 - 1e-49 166.0 6.9 2.7e-09 37.3 0.5 10.9 3 1 9 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD96948.1 - 1.4e-39 130.1 4.3 3.1e-05 23.7 0.0 12.8 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.1 EGD96948.1 - 3.2e-36 122.5 12.3 6e-07 29.5 0.0 9.0 5 2 6 11 11 11 8 Ankyrin repeats (many copies) gag-asp_proteas PF13975.1 EGD96948.1 - 0.03 14.1 0.1 3.4 7.5 0.0 3.5 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGD96948.1 - 0.032 14.7 0.3 10 6.6 0.0 4.3 4 1 0 4 4 4 0 Aspartyl protease RVP PF00077.15 EGD96948.1 - 0.036 13.9 0.1 17 5.4 0.0 3.8 3 1 1 4 4 4 0 Retroviral aspartyl protease Fungal_trans_2 PF11951.3 EGD96950.1 - 7.4e-30 103.8 0.3 1e-29 103.3 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD96950.1 - 1.4e-08 34.4 10.0 2.7e-08 33.5 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP1_TM PF14812.1 EGD96951.1 - 0.0043 17.3 3.4 0.0056 16.9 2.3 1.1 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal AF1Q PF15017.1 EGD96951.1 - 0.0071 16.2 2.1 0.0095 15.8 1.5 1.2 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator RXT2_N PF08595.6 EGD96951.1 - 0.014 15.2 1.2 0.014 15.1 0.8 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EGD96951.1 - 0.017 14.6 1.0 0.02 14.3 0.7 1.1 1 0 0 1 1 1 0 Nucleoplasmin Fucose_iso_N2 PF07882.7 EGD96951.1 - 0.022 14.4 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain FAM176 PF14851.1 EGD96951.1 - 0.046 13.4 0.1 0.049 13.3 0.0 1.1 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 EGD96951.1 - 0.07 13.3 2.7 0.08 13.1 1.8 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.1 EGD96951.1 - 0.12 11.5 1.3 0.11 11.6 0.9 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.4 EGD96951.1 - 0.13 10.9 6.8 0.14 10.8 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Herpes_LMP1 PF05297.6 EGD96951.1 - 0.78 8.6 5.4 0.95 8.3 3.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2076 PF09849.4 EGD96951.1 - 9.9 6.1 8.5 12 5.8 5.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) AA_permease PF00324.16 EGD96952.1 - 6.5e-138 460.0 37.3 8e-138 459.7 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD96952.1 - 6.3e-34 117.2 37.5 8.5e-34 116.8 26.0 1.1 1 0 0 1 1 1 1 Amino acid permease APH PF01636.18 EGD96953.1 - 1e-09 38.5 0.0 1.3e-06 28.3 0.0 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family DUF1679 PF07914.6 EGD96953.1 - 3e-05 22.8 0.1 0.24 9.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 EGD96953.1 - 0.0077 15.2 0.0 2.3 7.1 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase FCH PF00611.18 EGD96954.1 - 4.8e-15 55.5 0.1 2.7e-14 53.1 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EGD96954.1 - 5.6e-14 52.0 0.2 2.5e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 EGD96954.1 - 2.1e-08 33.7 0.0 4.1e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1053 PF06327.9 EGD96954.1 - 0.057 13.7 0.9 0.77 10.1 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) RTA1 PF04479.8 EGD96955.1 - 2e-13 50.3 0.3 2.7e-13 49.9 0.2 1.1 1 0 0 1 1 1 1 RTA1 like protein Asp-Al_Ex PF06826.7 EGD96955.1 - 0.035 13.5 0.4 0.069 12.6 0.2 1.4 1 0 0 1 1 1 0 Predicted Permease Membrane Region AAA_16 PF13191.1 EGD96956.1 - 1.6e-16 60.7 0.2 1.1e-14 54.8 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGD96956.1 - 1.2e-14 54.6 0.1 6.2e-14 52.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EGD96956.1 - 6.3e-14 52.3 0.0 1.6e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 EGD96956.1 - 1.3e-06 28.0 0.0 3.3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal NTPase_1 PF03266.10 EGD96956.1 - 0.00029 20.6 0.0 0.00051 19.7 0.0 1.4 1 0 0 1 1 1 1 NTPase NB-ARC PF00931.17 EGD96956.1 - 0.00032 19.6 0.0 0.00071 18.5 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain TIP49 PF06068.8 EGD96956.1 - 0.00056 18.7 0.0 0.00087 18.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Arch_ATPase PF01637.13 EGD96956.1 - 0.00057 19.6 0.0 0.0012 18.6 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 EGD96956.1 - 0.002 17.8 0.0 0.0046 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EGD96956.1 - 0.0029 17.3 0.0 0.0086 15.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain PIF1 PF05970.9 EGD96956.1 - 0.003 16.5 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase ABC_tran PF00005.22 EGD96956.1 - 0.0041 17.4 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 ABC transporter T2SE PF00437.15 EGD96956.1 - 0.0047 15.8 0.0 0.0096 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA12 PF10443.4 EGD96956.1 - 0.0056 15.2 0.0 0.0082 14.6 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein AAA_18 PF13238.1 EGD96956.1 - 0.0069 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGD96956.1 - 0.0083 16.2 0.1 0.024 14.8 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_17 PF13207.1 EGD96956.1 - 0.0083 16.9 0.0 0.015 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGD96956.1 - 0.0088 15.9 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGD96956.1 - 0.02 13.9 0.0 0.045 12.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KAP_NTPase PF07693.9 EGD96956.1 - 0.023 13.7 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain ArgK PF03308.11 EGD96956.1 - 0.026 13.2 0.0 0.047 12.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 EGD96956.1 - 0.027 14.4 0.0 0.076 12.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.4 EGD96956.1 - 0.043 12.7 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EGD96956.1 - 0.083 12.5 0.0 0.25 10.9 0.0 1.8 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 EGD96956.1 - 0.087 12.3 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain UBA_4 PF14555.1 EGD96957.1 - 1.6e-13 49.9 0.1 3.1e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EGD96957.1 - 1.9e-12 47.0 0.0 4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 EGD96957.1 - 4.5e-08 33.0 0.0 1.6e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 UBX domain DUF1299 PF06975.6 EGD96957.1 - 0.13 12.1 0.3 0.99 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) Pkinase PF00069.20 EGD96959.1 - 2.3e-69 233.4 0.0 3.2e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD96959.1 - 1.9e-50 171.3 0.0 2.8e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD96959.1 - 0.001 18.0 0.0 0.023 13.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like COesterase PF00135.23 EGD96960.1 - 2.1e-70 237.9 0.0 2.6e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD96960.1 - 2.4e-09 37.0 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD96960.1 - 0.055 12.6 0.1 0.11 11.6 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Fungal_trans PF04082.13 EGD96961.1 - 2.3e-24 85.7 0.0 3.3e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD96961.1 - 4.6e-08 32.8 12.1 8.2e-08 32.0 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 EGD96963.1 - 1.9e-21 76.0 0.0 3.6e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EGD96963.1 - 1.1e-10 41.8 0.0 2.4e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EGD96963.1 - 1.1e-09 38.3 0.0 1.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Beta-lactamase PF00144.19 EGD96964.1 - 1.8e-23 83.0 0.0 2.9e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase adh_short_C2 PF13561.1 EGD96965.1 - 8.3e-22 78.1 0.0 9.9e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD96965.1 - 1.8e-21 76.7 0.3 2.9e-21 76.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD96965.1 - 9.2e-06 25.4 0.2 1.4e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF3431 PF11913.3 EGD96966.1 - 4.8e-82 274.7 0.1 5.9e-82 274.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) FlxA PF14282.1 EGD96966.1 - 0.045 13.6 1.0 0.095 12.6 0.7 1.4 1 0 0 1 1 1 0 FlxA-like protein ox_reductase_C PF08635.5 EGD96970.1 - 0.081 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative oxidoreductase C terminal Amidohydro_2 PF04909.9 EGD96971.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.6 2 0 0 2 2 2 0 Amidohydrolase ADH_zinc_N PF00107.21 EGD96972.1 - 1.7e-24 85.8 0.3 2.4e-24 85.3 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD96972.1 - 4.1e-24 84.4 0.2 8.5e-24 83.4 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SWIM PF04434.12 EGD96973.1 - 2.5e-05 23.6 0.2 4.4e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger CENP-B_dimeris PF09026.5 EGD96973.1 - 0.86 9.8 8.7 1.1 9.5 5.1 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CobT PF06213.7 EGD96973.1 - 4.1 6.4 10.8 29 3.6 6.3 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT PPP4R2 PF09184.6 EGD96973.1 - 5.8 6.3 9.9 21 4.5 7.1 1.6 2 0 0 2 2 2 0 PPP4R2 SET PF00856.23 EGD96975.1 - 6.8e-07 29.7 0.3 7.5e-05 23.0 0.2 2.9 2 0 0 2 2 2 1 SET domain TPR_11 PF13414.1 EGD96975.1 - 4.6e-06 26.1 0.3 1.3e-05 24.7 0.2 1.7 1 0 0 1 1 1 1 TPR repeat TPR_9 PF13371.1 EGD96975.1 - 0.0068 16.2 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD96975.1 - 0.012 16.2 0.1 0.037 14.7 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat SAP PF02037.22 EGD96975.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 SAP domain Allexi_40kDa PF05549.6 EGD96976.1 - 0.13 11.5 0.0 0.13 11.5 0.0 2.8 3 0 0 3 3 3 0 Allexivirus 40kDa protein zf-H2C2_2 PF13465.1 EGD96977.1 - 5.5e-12 45.3 15.0 3.7e-05 23.7 0.8 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGD96977.1 - 3.1e-08 33.4 22.5 0.012 15.8 4.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD96977.1 - 2.4e-05 24.3 21.3 0.0085 16.3 4.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD96977.1 - 0.045 13.9 10.1 0.51 10.5 1.9 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EGD96977.1 - 0.18 11.9 7.6 0.34 11.0 5.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EGD96977.1 - 0.28 11.1 11.9 0.37 10.7 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DZR PF12773.2 EGD96977.1 - 1.1 9.1 5.3 10 6.0 3.6 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EGD96977.1 - 1.2 9.1 8.0 12 5.9 2.6 3.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 EGD96977.1 - 3.9 7.6 11.4 2.5 8.2 1.1 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.7 EGD96977.1 - 6.3 6.8 6.3 17 5.4 4.2 2.0 1 1 0 1 1 1 0 TFIIH C1-like domain DUF3074 PF11274.3 EGD96978.1 - 6.7e-13 48.6 0.0 3.6e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) Stk19 PF10494.4 EGD96979.1 - 1.4e-66 224.4 0.0 1.8e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Glyco_transf_20 PF00982.16 EGD96980.1 - 7.7e-157 522.5 0.1 1.2e-156 521.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EGD96980.1 - 5.9e-35 120.2 0.0 1.1e-33 116.1 0.0 2.3 1 1 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 EGD96980.1 - 0.015 14.8 0.7 0.066 12.7 0.3 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain 4HBT_3 PF13622.1 EGD96982.1 - 2e-55 188.3 0.0 2.3e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EGD96983.1 - 3.7e-05 23.7 0.0 5.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.14 EGD96983.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain PCI PF01399.22 EGD96985.1 - 3.7e-12 46.4 0.1 1.5e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 PCI domain DUF1690 PF07956.6 EGD96985.1 - 0.0062 16.5 2.2 0.014 15.4 1.5 1.5 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) RNase_P_Rpp14 PF01900.14 EGD96985.1 - 0.046 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Rpp14/Pop5 family DUF883 PF05957.8 EGD96985.1 - 0.18 12.1 9.4 0.9 9.9 3.1 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Ribosomal_S14 PF00253.16 EGD96986.1 - 2.8e-17 61.8 5.8 3e-17 61.7 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF1451 PF07295.6 EGD96986.1 - 0.16 11.7 0.4 0.16 11.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Prim_Zn_Ribbon PF08273.7 EGD96986.1 - 0.18 11.9 3.3 7.1 6.8 0.4 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase ADK PF00406.17 EGD96987.1 - 9.5e-41 139.1 0.1 2.8e-40 137.6 0.0 1.7 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EGD96987.1 - 5.3e-10 39.6 0.0 8.4e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD96987.1 - 6.8e-08 33.3 0.0 1.2e-07 32.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGD96987.1 - 5e-06 26.4 0.0 4.6e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EGD96987.1 - 0.0015 17.9 0.1 0.013 14.8 0.1 2.0 1 1 0 1 1 1 1 Thymidylate kinase MFS_1 PF07690.11 EGD96989.1 - 9.7e-30 103.4 29.6 1.4e-29 102.9 20.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2637 PF10935.3 EGD96989.1 - 2.1 8.2 6.8 6 6.7 4.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2637) DUF998 PF06197.8 EGD96989.1 - 2.4 7.4 23.1 3.3 6.9 9.0 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF998) MARVEL PF01284.18 EGD96991.1 - 0.015 15.1 0.4 0.015 15.1 0.3 1.9 2 0 0 2 2 2 0 Membrane-associating domain DUF3816 PF12822.2 EGD96991.1 - 0.12 12.2 2.5 0.17 11.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) Zip PF02535.17 EGD96991.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter GPI2 PF06432.6 EGD96991.1 - 0.18 11.1 3.5 6.2 6.0 0.9 2.2 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Hum_adeno_E3A PF05393.6 EGD96991.1 - 0.92 9.2 3.8 1.1 8.9 0.2 2.4 1 1 1 2 2 2 0 Human adenovirus early E3A glycoprotein Cnd2 PF05786.9 EGD96992.1 - 3.1e-237 789.6 4.7 3.9e-237 789.3 3.3 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Sigma70_ner PF04546.8 EGD96992.1 - 8.4 5.9 9.7 0.34 10.5 1.1 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Na_Ca_ex PF01699.19 EGD96993.1 - 8.8e-46 154.9 32.4 7e-24 84.0 8.7 2.7 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Vpu PF00558.14 EGD96993.1 - 0.75 9.3 2.0 9.6 5.8 0.0 2.6 2 0 0 2 2 2 0 Vpu protein EF-hand_4 PF12763.2 EGD96994.1 - 1.5e-24 85.7 0.0 1.2e-12 47.4 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EGD96994.1 - 1.8e-10 40.0 0.2 5.5e-10 38.5 0.1 1.9 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.6 EGD96994.1 - 1.2e-06 28.5 145.0 0.0005 20.0 24.4 6.7 3 2 2 5 5 5 4 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 EGD96994.1 - 8.2e-05 22.6 0.0 0.013 15.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGD96994.1 - 0.00039 19.5 0.0 0.13 11.5 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EGD96994.1 - 0.0067 16.0 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EGD96994.1 - 0.16 11.8 0.0 12 6.0 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain RNA_pol_L_2 PF13656.1 EGD96995.1 - 2.5e-23 81.2 0.0 3.6e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EGD96995.1 - 1.5e-11 43.2 0.0 2.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SIR2_2 PF13289.1 EGD96995.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 SIR2-like domain NMO PF03060.10 EGD96996.1 - 1.1e-38 133.2 4.6 9.6e-31 107.1 1.0 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EGD96996.1 - 1.6e-07 30.5 2.8 2.7e-07 29.7 2.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EGD96996.1 - 9.4e-05 21.4 0.4 0.071 11.9 1.5 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EGD96996.1 - 0.00052 19.0 1.3 0.0007 18.6 0.9 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase DUF506 PF04720.7 EGD96998.1 - 0.12 11.9 4.7 0.14 11.7 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Dicty_REP PF05086.7 EGD96998.1 - 0.16 9.7 3.7 0.18 9.5 2.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SOBP PF15279.1 EGD96998.1 - 2.7 8.2 5.5 3.3 7.9 3.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF972 PF06156.8 EGD96998.1 - 8.8 6.7 8.5 1.6 9.0 3.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) LRR_8 PF13855.1 EGD96999.1 - 9.7e-07 28.4 4.5 0.12 12.1 0.2 5.3 3 2 3 6 6 6 3 Leucine rich repeat LRR_4 PF12799.2 EGD96999.1 - 5.4e-06 25.8 0.4 0.42 10.2 0.2 5.0 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EGD96999.1 - 0.005 16.7 6.5 44 4.6 0.0 7.1 8 1 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.28 EGD96999.1 - 0.016 15.1 5.4 68 4.0 0.0 6.3 7 1 1 8 8 8 0 Leucine Rich Repeat BSP_II PF05432.6 EGD96999.1 - 0.16 11.1 9.1 0.24 10.6 6.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF966 PF06136.8 EGD96999.1 - 0.92 8.8 7.4 1.4 8.2 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mt_ATP-synt_B PF05405.9 EGD96999.1 - 3.4 7.0 11.3 6 6.3 7.8 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SNF2_N PF00176.18 EGD97000.1 - 6.2e-63 212.3 0.1 1e-62 211.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD97000.1 - 6.4e-12 45.1 0.0 1.6e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EGD97000.1 - 5.4e-05 22.7 11.5 5.4e-05 22.7 8.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD97000.1 - 0.00049 19.8 11.5 0.00049 19.8 8.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGD97000.1 - 0.0017 18.2 11.5 0.0017 18.2 7.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) C2 PF00168.25 EGD97001.1 - 2.5e-08 33.6 0.0 4.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pex2_Pex12 PF04757.9 EGD97002.1 - 3.8e-42 144.2 5.0 5.1e-42 143.8 3.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EGD97002.1 - 2.9e-11 42.9 9.8 4.7e-11 42.3 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGD97002.1 - 1.2e-10 40.9 7.6 1.8e-10 40.3 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD97002.1 - 1.9e-10 40.6 9.4 2.9e-10 39.9 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD97002.1 - 1.8e-09 37.1 5.7 2.6e-09 36.6 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD97002.1 - 5.3e-08 32.4 6.7 8.1e-08 31.8 4.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGD97002.1 - 3.4e-06 26.8 9.4 5.8e-06 26.0 6.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD97002.1 - 4e-06 26.4 2.3 4.5e-06 26.2 0.7 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGD97002.1 - 3.3e-05 23.9 7.4 7.5e-05 22.7 5.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EGD97002.1 - 0.0012 18.6 3.3 0.0021 17.8 2.3 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EGD97002.1 - 0.0063 16.3 3.0 0.011 15.5 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EGD97002.1 - 0.0092 15.4 4.8 0.017 14.6 3.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EGD97002.1 - 0.12 12.0 8.2 0.22 11.1 5.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 EGD97002.1 - 1.3 8.8 7.3 3.9 7.4 5.0 1.8 1 1 0 1 1 1 0 IBR domain EXS PF03124.9 EGD97003.1 - 2.3e-94 316.2 7.2 2.6e-94 316.0 5.0 1.0 1 0 0 1 1 1 1 EXS family DUF3431 PF11913.3 EGD97004.1 - 5.6e-85 284.3 1.2 6.8e-85 284.0 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) NIR_SIR PF01077.17 EGD97005.1 - 8.3e-52 174.7 0.0 1.3e-43 148.0 0.0 2.9 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EGD97005.1 - 8.9e-29 98.9 0.0 7.3e-14 51.1 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EGD97005.1 - 7.7e-28 97.2 0.0 1.5e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EGD97005.1 - 1.4e-05 24.6 0.7 4.4e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 EGD97006.1 - 1.4e-50 171.5 0.1 2.1e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Ras PF00071.17 EGD97007.1 - 6.8e-60 201.1 0.5 8.8e-60 200.7 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD97007.1 - 3.3e-20 72.7 0.1 5.3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD97007.1 - 4.5e-18 65.0 0.4 5.5e-18 64.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGD97007.1 - 2.1e-07 30.5 0.1 9.7e-07 28.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGD97007.1 - 7.4e-06 25.2 0.2 9e-06 24.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGD97007.1 - 9.5e-06 25.5 0.1 1.6e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGD97007.1 - 1.2e-05 24.5 0.1 1.9e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EGD97007.1 - 0.025 14.4 0.2 2.9 7.6 0.0 2.6 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 EGD97007.1 - 0.03 14.2 0.4 0.079 12.8 0.2 1.8 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EGD97007.1 - 0.073 12.7 0.1 0.25 11.0 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase CbiA PF01656.18 EGD97007.1 - 0.11 11.8 0.1 0.36 10.2 0.1 1.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP-synt_C PF00137.16 EGD97008.1 - 4e-27 93.8 25.8 3e-18 65.4 5.5 2.5 2 0 0 2 2 2 2 ATP synthase subunit C MoCF_biosynth PF00994.19 EGD97009.1 - 1.2e-50 170.6 0.1 1.5e-25 89.2 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EGD97009.1 - 2.3e-34 118.0 1.8 3.5e-34 117.4 1.3 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EGD97009.1 - 2.2e-18 65.9 0.1 5e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DDHD PF02862.12 EGD97010.1 - 1e-43 149.7 0.0 1.6e-41 142.6 0.0 2.8 2 1 0 2 2 2 1 DDHD domain Ribosomal_S9 PF00380.14 EGD97010.1 - 0.025 14.8 0.0 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S9/S16 Abhydrolase_6 PF12697.2 EGD97010.1 - 0.041 13.7 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD97010.1 - 0.067 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 EGD97012.1 - 2.1e-70 237.5 0.0 2.6e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGD97012.1 - 3e-38 131.0 0.0 5.3e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EGD97012.1 - 0.00044 19.2 0.0 0.0023 16.9 0.0 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGD97012.1 - 0.0074 16.6 0.0 0.023 15.0 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD97012.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGD97012.1 - 0.036 13.9 0.1 0.18 11.6 0.0 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EGD97012.1 - 0.05 13.0 0.0 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Toxin_51 PF15531.1 EGD97012.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 51 Lycopene_cycl PF05834.7 EGD97012.1 - 0.19 10.5 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EGD97012.1 - 0.23 9.8 0.0 0.39 9.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein LSM PF01423.17 EGD97013.1 - 2.3e-17 62.2 0.6 3e-17 61.9 0.4 1.2 1 0 0 1 1 1 1 LSM domain Myc_N PF01056.13 EGD97014.1 - 0.24 10.5 4.6 0.28 10.2 3.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PI3K_1B_p101 PF10486.4 EGD97014.1 - 0.51 7.8 3.2 0.57 7.6 2.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3778 PF12620.3 EGD97014.1 - 2.1 7.9 4.9 1.6 8.3 2.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3778) Nucleoplasmin PF03066.10 EGD97014.1 - 9.8 5.6 6.7 13 5.3 4.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin Ras PF00071.17 EGD97015.1 - 2.7e-47 160.1 0.0 3.4e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD97015.1 - 2.6e-11 44.0 0.0 4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD97015.1 - 0.00014 21.1 0.0 0.00031 20.0 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGD97015.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PAP2 PF01569.16 EGD97016.1 - 4.5e-17 61.9 2.6 4.5e-17 61.9 1.8 1.8 2 0 0 2 2 2 1 PAP2 superfamily Peptidase_C48 PF02902.14 EGD97018.1 - 2.2e-26 92.8 0.0 3.3e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3628 PF12300.3 EGD97019.1 - 0.07 13.1 8.7 0.12 12.3 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) LPP PF04728.8 EGD97021.1 - 0.001 18.8 3.1 0.07 12.9 0.2 3.5 1 1 2 3 3 3 1 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 EGD97021.1 - 0.0046 16.1 4.1 0.018 14.2 2.7 1.8 1 1 0 1 1 1 1 Reovirus sigma C capsid protein ADIP PF11559.3 EGD97021.1 - 0.0059 16.5 2.1 0.33 10.8 0.2 2.4 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Laminin_I PF06008.9 EGD97021.1 - 0.042 13.1 0.3 0.15 11.3 0.0 1.8 1 1 1 2 2 2 0 Laminin Domain I BicD PF09730.4 EGD97021.1 - 0.045 12.1 1.4 0.079 11.2 1.0 1.3 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D COG5 PF10392.4 EGD97021.1 - 0.052 13.5 1.2 0.33 10.9 0.8 2.4 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.7 EGD97021.1 - 0.056 13.2 0.2 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EGD97021.1 - 0.058 13.2 4.8 2.7 7.7 0.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) WEMBL PF05701.6 EGD97021.1 - 0.059 11.8 0.1 0.09 11.2 0.1 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 EGD97021.1 - 0.073 12.9 0.6 0.5 10.2 0.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 EGD97021.1 - 0.17 12.1 2.1 38 4.6 0.0 3.4 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.6 EGD97021.1 - 0.29 10.9 2.9 0.8 9.4 2.0 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) RasGAP_C PF03836.10 EGD97021.1 - 0.59 9.8 3.0 0.28 10.8 0.1 1.9 3 0 0 3 3 3 0 RasGAP C-terminus Fib_alpha PF08702.5 EGD97021.1 - 0.6 10.2 3.9 2 8.5 0.7 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Macoilin PF09726.4 EGD97021.1 - 0.65 8.2 6.5 0.031 12.5 0.5 1.6 2 0 0 2 2 2 0 Transmembrane protein Sulfotransfer_3 PF13469.1 EGD97022.1 - 0.0033 18.3 0.6 0.01 16.7 0.4 1.8 1 1 0 1 1 1 1 Sulfotransferase family Pepsin-I3 PF06394.8 EGD97022.1 - 0.11 12.2 0.3 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain DUF1542 PF07564.6 EGD97023.1 - 0.0036 17.2 0.1 0.0082 16.1 0.1 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1542) Sulfotransfer_3 PF13469.1 EGD97023.1 - 0.021 15.7 0.1 0.067 14.1 0.1 1.7 1 1 0 1 1 1 0 Sulfotransferase family adh_short PF00106.20 EGD97024.1 - 4.2e-29 101.6 0.0 6e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD97024.1 - 1.3e-24 87.3 0.1 1.5e-24 87.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD97024.1 - 1.7e-12 47.4 0.2 4.2e-12 46.0 0.1 1.6 1 1 0 1 1 1 1 KR domain zf-HIT PF04438.11 EGD97025.1 - 6.3e-10 38.5 10.8 1.1e-09 37.7 7.5 1.4 1 0 0 1 1 1 1 HIT zinc finger DENN PF02141.16 EGD97027.1 - 1.1e-37 129.5 0.0 2.1e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EGD97027.1 - 0.00015 21.6 0.0 0.00048 20.0 0.0 1.9 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 EGD97027.1 - 0.18 12.1 12.2 0.017 15.4 4.5 2.3 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TMF_TATA_bd PF12325.3 EGD97027.1 - 1.9 8.2 18.3 0.31 10.7 3.9 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DivIVA PF05103.8 EGD97027.1 - 3.3 7.7 14.1 0.67 10.0 4.4 2.7 1 1 1 2 2 2 0 DivIVA protein Git3 PF11710.3 EGD97028.1 - 1.2e-23 83.8 17.5 2.7e-23 82.5 12.1 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EGD97028.1 - 7.9e-10 38.3 0.5 7.9e-10 38.3 0.4 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term MOR2-PAG1_N PF14222.1 EGD97029.1 - 6.1e-224 744.8 0.0 1.1e-223 743.9 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EGD97029.1 - 9.9e-75 251.6 0.2 3.6e-57 194.0 0.0 2.8 1 1 1 2 2 2 2 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EGD97029.1 - 3.5e-40 137.5 11.7 7.6e-17 60.2 0.0 3.9 2 1 1 3 3 3 3 Cell morphogenesis central region FAD_binding_1 PF00667.15 EGD97030.1 - 1.9e-50 171.3 0.0 5e-50 169.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGD97030.1 - 4.4e-34 117.5 0.8 8.9e-34 116.5 0.5 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EGD97030.1 - 2.2e-23 82.8 0.0 2e-22 79.8 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EGD97030.1 - 0.01 15.8 0.1 0.26 11.2 0.0 2.6 2 0 0 2 2 2 0 Flavodoxin domain RRM_1 PF00076.17 EGD97031.1 - 5.6e-22 77.1 0.3 1.1e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD97031.1 - 3.2e-15 55.8 0.1 1.4e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD97031.1 - 1.5e-05 24.7 1.9 0.075 12.8 0.1 2.7 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAPS_reduct PF01507.14 EGD97032.1 - 4.5e-29 101.4 0.0 3.4e-27 95.3 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RPA_C PF08784.6 EGD97033.1 - 1e-12 48.3 0.1 3.5e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EGD97033.1 - 0.00034 20.4 0.0 0.002 17.9 0.0 2.1 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DEAD PF00270.24 EGD97034.1 - 2.7e-43 147.3 0.0 5.4e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD97034.1 - 1e-22 79.7 0.2 4.4e-22 77.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EGD97034.1 - 6.3e-20 70.7 3.0 2.3e-19 68.9 2.1 2.1 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Zn_clus PF00172.13 EGD97036.1 - 0.00025 20.8 10.5 0.00044 20.0 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3169 PF11368.3 EGD97037.1 - 0.12 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) AA_permease PF00324.16 EGD97038.1 - 1.4e-102 343.5 33.4 1.6e-102 343.3 23.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD97038.1 - 7.5e-36 123.5 38.1 8.7e-36 123.3 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 EGD97038.1 - 0.03 14.4 1.8 0.03 14.4 1.3 3.5 3 1 0 3 3 3 0 PrgI family protein DEAD PF00270.24 EGD97039.1 - 1.8e-45 154.4 0.1 3.3e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGD97039.1 - 1.7e-25 88.2 0.1 3.5e-25 87.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGD97039.1 - 2.7e-22 78.4 0.0 7.9e-22 76.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EGD97039.1 - 0.00046 20.1 0.2 0.0017 18.3 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.18 EGD97039.1 - 0.0024 16.7 0.0 0.0045 15.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGD97039.1 - 0.0031 17.3 0.0 0.0031 17.3 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DnaJ PF00226.26 EGD97040.1 - 1.1e-14 53.8 2.9 1.8e-14 53.2 0.6 2.3 2 0 0 2 2 2 1 DnaJ domain CT47 PF15623.1 EGD97040.1 - 0.71 9.5 8.7 1.1 8.9 6.0 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 MatE PF01554.13 EGD97041.1 - 2.5e-52 176.7 29.2 1.6e-29 102.6 7.8 2.3 2 0 0 2 2 2 2 MatE 2TM PF13239.1 EGD97041.1 - 4.5 7.3 10.7 1.1 9.3 1.1 3.1 3 0 0 3 3 3 0 2TM domain DUF202 PF02656.10 EGD97042.1 - 9.3e-20 70.6 1.2 9.3e-20 70.6 0.8 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF2499 PF10693.4 EGD97042.1 - 0.027 14.4 0.3 0.067 13.2 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2499) COX4_pro_2 PF07835.7 EGD97042.1 - 0.054 13.4 0.9 0.47 10.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV SPT16 PF08644.6 EGD97042.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF2427 PF10348.4 EGD97042.1 - 0.95 9.0 4.0 1.4 8.5 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) NUDIX PF00293.23 EGD97043.1 - 5.7e-29 100.4 0.0 7.9e-29 100.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_2 PF00152.15 EGD97045.1 - 4.6e-57 193.2 0.0 7.7e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGD97045.1 - 1e-07 31.6 0.0 3.1e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain CPSF100_C PF13299.1 EGD97047.1 - 1.4e-42 145.6 0.1 1.4e-42 145.6 0.1 2.1 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EGD97047.1 - 1.6e-28 99.1 0.0 4.5e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EGD97047.1 - 0.0016 18.2 0.0 0.0046 16.7 0.0 1.8 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EGD97047.1 - 0.0019 17.7 0.0 0.08 12.4 0.0 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGD97047.1 - 0.09 12.4 0.2 0.44 10.1 0.1 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily DUF1664 PF07889.7 EGD97049.1 - 0.022 14.5 0.3 0.19 11.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HemX PF04375.9 EGD97049.1 - 0.07 11.7 0.0 0.087 11.3 0.0 1.0 1 0 0 1 1 1 0 HemX Cytochrom_B562 PF07361.6 EGD97049.1 - 0.079 13.3 2.0 0.11 12.8 0.4 1.7 1 1 1 2 2 2 0 Cytochrome b562 Apolipoprotein PF01442.13 EGD97049.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EGD97049.1 - 0.64 10.4 4.5 0.49 10.8 1.4 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Frag1 PF10277.4 EGD97050.1 - 4.9e-43 147.1 6.5 4.9e-43 147.1 4.5 2.5 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family U3_assoc_6 PF08640.6 EGD97051.1 - 9.4e-29 99.0 2.1 1.4e-28 98.4 0.6 1.9 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EGD97051.1 - 0.00025 21.3 3.2 0.074 13.7 0.3 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EGD97051.1 - 0.0094 14.8 0.2 0.014 14.2 0.1 1.3 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_15 PF13429.1 EGD97051.1 - 0.0097 14.9 0.9 0.017 14.1 0.6 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Suf PF05843.9 EGD97051.1 - 0.0098 15.6 0.2 1.4 8.6 0.0 2.9 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) Tropomyosin_1 PF12718.2 EGD97051.1 - 0.11 12.3 0.2 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Tropomyosin like RF-1 PF00472.15 EGD97052.1 - 5.2e-16 58.4 0.8 8.4e-16 57.7 0.5 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 EGD97052.1 - 0.00091 19.3 0.1 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Aconitase PF00330.15 EGD97052.1 - 0.037 12.4 0.2 0.048 12.1 0.2 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) RRM_1 PF00076.17 EGD97053.1 - 7.3e-10 38.3 0.0 1.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD97053.1 - 2.1e-07 30.8 0.0 4.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1908 PF08926.6 EGD97053.1 - 0.0061 15.3 0.0 0.02 13.6 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1908) RRM_5 PF13893.1 EGD97053.1 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.12 EGD97054.1 - 1.6e-23 82.5 3.9 2e-23 82.1 2.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 EGD97054.1 - 0.093 12.8 0.3 0.13 12.3 0.2 1.3 1 1 0 1 1 1 0 Prolamin-like CHCH PF06747.8 EGD97054.1 - 0.17 11.8 2.8 1.5 8.8 0.5 2.5 2 1 0 2 2 2 0 CHCH domain SYS1 PF09801.4 EGD97055.1 - 1.6e-52 177.3 8.0 1.9e-52 177.1 5.6 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.7 EGD97055.1 - 0.018 14.7 2.8 0.018 14.7 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF485 COG5 PF10392.4 EGD97056.1 - 1.1e-37 128.9 1.3 3.3e-37 127.3 0.0 2.4 3 0 0 3 3 3 1 Golgi transport complex subunit 5 zf-C2H2_4 PF13894.1 EGD97058.1 - 3.7e-06 26.8 13.3 0.00058 20.0 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGD97058.1 - 7.2e-06 26.0 4.0 7.2e-06 26.0 2.8 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGD97058.1 - 8e-05 22.7 11.6 0.03 14.6 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type AMP-binding PF00501.23 EGD97060.1 - 6.3e-156 518.9 0.0 2.3e-80 270.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EGD97060.1 - 8e-76 254.7 0.1 2.5e-38 131.6 0.0 2.8 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EGD97060.1 - 1e-21 76.9 0.0 1.4e-11 44.4 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD97060.1 - 8e-10 39.5 0.0 5.2e-05 24.1 0.0 3.2 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EGD97060.1 - 0.32 9.4 0.0 10 4.5 0.0 2.8 3 0 0 3 3 3 0 GH3 auxin-responsive promoter MFS_1 PF07690.11 EGD97061.1 - 5.6e-38 130.5 51.8 5.6e-38 130.5 35.9 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD97061.1 - 2.2e-16 59.1 24.7 3.7e-16 58.4 17.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGD97061.1 - 2e-07 29.9 17.3 2e-07 29.9 12.0 3.1 3 1 0 3 3 3 2 Sugar (and other) transporter p450 PF00067.17 EGD97062.1 - 2.1e-56 191.4 0.0 2.4e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_33 PF10017.4 EGD97063.1 - 1.1e-22 80.3 0.0 1.5e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent MutS_V PF00488.16 EGD97064.1 - 1.2e-95 319.4 0.0 1.9e-95 318.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGD97064.1 - 1.3e-38 132.8 0.5 2.7e-38 131.8 0.3 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EGD97064.1 - 3.8e-23 82.0 0.2 2.3e-22 79.5 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.15 EGD97064.1 - 1.6e-16 60.3 0.0 1.1e-15 57.6 0.0 2.3 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EGD97064.1 - 8.3e-15 54.7 0.8 2.9e-14 52.9 0.6 2.0 1 0 0 1 1 1 1 MutS family domain IV Gpi1 PF05024.10 EGD97065.1 - 2.8e-61 206.4 10.5 3.3e-61 206.2 6.4 1.7 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.7 EGD97067.1 - 2.8e-29 100.7 2.7 3.4e-29 100.5 1.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EGD97067.1 - 0.00079 19.4 1.0 0.0017 18.3 0.7 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EGD97067.1 - 0.00081 19.1 3.7 0.2 11.4 0.1 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like ARL2_Bind_BART PF11527.3 EGD97067.1 - 0.012 15.4 0.3 0.013 15.2 0.2 1.2 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART UCR_hinge PF02320.11 EGD97067.1 - 0.045 13.6 1.3 2.6 8.0 0.1 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Meth_synt_1 PF08267.7 EGD97067.1 - 0.058 12.6 0.0 0.072 12.3 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain COX6B PF02297.12 EGD97067.1 - 1.1 9.3 6.9 1.1 9.3 0.5 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DNA_pol_A_exo1 PF01612.15 EGD97068.1 - 3.2e-41 140.7 0.5 5.1e-41 140.0 0.3 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 EGD97068.1 - 7.9e-12 44.7 0.5 2e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 HRDC domain PMC2NT PF08066.7 EGD97068.1 - 5.9e-10 39.3 2.3 1.2e-09 38.2 0.1 2.7 2 1 0 2 2 2 1 PMC2NT (NUC016) domain Zip PF02535.17 EGD97068.1 - 0.07 12.1 2.6 0.13 11.2 1.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Med3 PF11593.3 EGD97068.1 - 0.46 9.6 10.5 0.29 10.3 0.2 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal CDK5_activator PF03261.10 EGD97068.1 - 0.85 8.8 2.8 1.8 7.8 2.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SelP_N PF04592.9 EGD97068.1 - 1.7 7.9 10.0 3.3 7.0 6.9 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BAF1_ABF1 PF04684.8 EGD97068.1 - 2.8 6.6 31.1 0.018 13.9 14.0 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor RasGAP PF00616.14 EGD97069.1 - 3.4e-54 183.5 0.2 1.4e-53 181.5 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EGD97069.1 - 2.3e-32 111.6 5.8 2.3e-32 111.6 4.0 2.4 2 0 0 2 2 2 1 RasGAP C-terminus DUF1647 PF07801.6 EGD97069.1 - 0.3 10.5 3.9 0.12 11.8 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1647) DUF972 PF06156.8 EGD97069.1 - 5 7.5 12.1 17 5.7 2.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CRAL_TRIO PF00650.15 EGD97070.1 - 1e-38 132.3 0.0 1.4e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGD97070.1 - 2.6e-08 33.8 0.4 2.6e-08 33.8 0.3 3.0 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGD97070.1 - 5.9e-06 26.2 0.0 1.2e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain BSP_II PF05432.6 EGD97070.1 - 0.08 12.2 10.0 0.12 11.6 6.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RR_TM4-6 PF06459.7 EGD97070.1 - 0.29 11.0 6.6 0.41 10.4 4.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.5 EGD97070.1 - 7.7 6.4 14.1 15 5.5 9.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mis14 PF08641.7 EGD97071.1 - 7.8e-22 77.8 6.4 1.5e-21 76.9 4.4 1.6 1 1 0 1 1 1 1 Kinetochore protein Mis14 like UPF0515 PF15135.1 EGD97071.1 - 0.17 10.9 0.7 0.25 10.3 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Acetyltransf_1 PF00583.19 EGD97074.1 - 1.7e-18 66.3 0.0 2.5e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD97074.1 - 6.2e-12 45.5 0.0 9.5e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD97074.1 - 2e-11 43.5 0.0 3.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGD97074.1 - 4.4e-11 42.9 0.0 5.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGD97074.1 - 9.9e-09 35.4 0.0 1.8e-08 34.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGD97074.1 - 4.9e-08 32.9 0.0 7.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD97074.1 - 2.4e-06 27.4 0.1 6.1e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGD97074.1 - 0.00013 21.9 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD97074.1 - 0.00095 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.1 EGD97074.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase LCAT PF02450.10 EGD97075.1 - 5.2e-91 305.5 0.0 6.7e-91 305.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 EGD97075.1 - 0.0016 18.3 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 EGD97075.1 - 0.0036 16.6 0.1 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_5 PF12695.2 EGD97075.1 - 0.0068 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family HutD PF05962.6 EGD97075.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 HutD PGAP1 PF07819.8 EGD97075.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PAP2 PF01569.16 EGD97076.1 - 3.8e-12 45.9 6.8 3.8e-12 45.9 4.7 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EGD97076.1 - 4.2e-08 32.9 4.1 4.2e-08 32.9 2.8 2.1 2 1 0 2 2 2 1 PAP2 superfamily MFS_1 PF07690.11 EGD97078.1 - 1.9e-32 112.3 25.7 1.9e-32 112.3 17.8 2.4 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD97078.1 - 8.2e-32 110.3 25.6 7.5e-31 107.1 17.7 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.20 EGD97079.1 - 3.6e-06 26.3 0.0 7e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Plasmid_Txe PF06769.8 EGD97079.1 - 0.00029 20.5 0.0 0.00052 19.7 0.0 1.5 1 0 0 1 1 1 1 Plasmid encoded toxin Txe GHMP_kinases_C PF08544.8 EGD97079.1 - 0.093 12.9 0.0 7.6 6.8 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal DUF1768 PF08719.6 EGD97080.1 - 7e-50 168.8 0.0 8e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pkinase PF00069.20 EGD97081.1 - 2.4e-30 105.5 0.0 3.7e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97081.1 - 1.7e-07 30.6 0.0 0.0066 15.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase SpoIIIAH PF12685.2 EGD97082.1 - 0.021 14.3 0.2 0.023 14.1 0.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein TMEMspv1-c74-12 PF11044.3 EGD97082.1 - 0.033 13.7 0.7 0.12 11.9 0.1 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF1310 PF07006.6 EGD97082.1 - 0.045 13.2 1.9 0.065 12.7 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1310) DUF106 PF01956.11 EGD97082.1 - 0.13 11.8 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 GRP PF07172.6 EGD97082.1 - 0.17 12.3 0.9 0.32 11.4 0.6 1.6 1 1 0 1 1 1 0 Glycine rich protein family Chordopox_A13L PF05961.6 EGD97082.1 - 0.25 11.3 1.0 0.44 10.5 0.6 1.6 1 1 0 1 1 1 0 Chordopoxvirus A13L protein DUF4307 PF14155.1 EGD97082.1 - 0.39 10.5 6.1 4.9 6.9 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) DUF2275 PF10039.4 EGD97082.1 - 0.61 9.9 2.6 1.1 9.1 1.6 1.4 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2275) cNMP_binding PF00027.24 EGD97087.1 - 9.2e-42 140.7 0.0 2.6e-20 72.0 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 2OG-FeII_Oxy_3 PF13640.1 EGD97088.1 - 1.3e-10 41.6 0.0 2.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGD97088.1 - 2.3e-07 30.3 0.0 5.4e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGD97088.1 - 0.00012 22.2 0.0 0.0002 21.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fork_head PF00250.13 EGD97089.1 - 8e-17 61.0 0.1 1.5e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EGD97089.1 - 0.0005 20.1 0.0 0.00098 19.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain Snf7 PF03357.16 EGD97090.1 - 6.9e-32 110.1 18.4 6.9e-32 110.1 12.8 2.0 1 1 1 2 2 2 1 Snf7 NuA4 PF09340.5 EGD97090.1 - 1.6 8.4 4.5 0.46 10.1 0.3 2.4 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Allexi_40kDa PF05549.6 EGD97090.1 - 6 6.0 8.6 8.3 5.6 5.3 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein Ten1 PF12658.2 EGD97091.1 - 2.3e-40 137.1 0.0 2.7e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EGD97091.1 - 0.0017 17.9 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Kelch_5 PF13854.1 EGD97092.1 - 4.5e-19 67.9 9.1 3.4e-09 36.4 0.1 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 EGD97092.1 - 4.2e-13 48.8 11.1 0.0069 16.1 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EGD97092.1 - 1.4e-12 47.3 6.1 1e-05 25.5 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EGD97092.1 - 2.3e-10 40.2 7.7 0.0013 18.7 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EGD97092.1 - 1.1e-06 28.1 1.4 0.13 12.0 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EGD97092.1 - 4.6e-05 22.8 2.6 0.86 9.1 0.0 4.6 4 0 0 4 4 4 2 Kelch motif BCAS2 PF05700.6 EGD97093.1 - 8.1e-52 175.8 0.3 9e-52 175.7 0.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ceramidase_alk PF04734.8 EGD97094.1 - 6.5e-205 681.9 0.0 2.5e-204 680.0 0.0 1.7 2 0 0 2 2 2 1 Neutral/alkaline non-lysosomal ceramidase EI24 PF07264.6 EGD97096.1 - 4.4e-07 29.5 0.6 4.4e-07 29.5 0.4 2.3 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) HNH PF01844.18 EGD97097.1 - 0.00041 20.1 2.4 0.00078 19.2 1.7 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF1364 PF07102.7 EGD97097.1 - 0.057 13.3 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) GTP_EFTU PF00009.22 EGD97099.1 - 4.6e-37 127.2 4.2 3.1e-36 124.5 2.9 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGD97099.1 - 9.8e-26 89.7 2.3 1.5e-25 89.2 0.7 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EGD97099.1 - 2.7e-14 53.0 0.6 3.3e-06 27.1 0.0 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EGD97099.1 - 6.2e-09 35.3 0.0 5e-08 32.4 0.0 2.4 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EGD97099.1 - 5.2e-08 32.8 0.1 1.1e-07 31.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD97099.1 - 2e-06 28.2 0.1 6.4e-06 26.6 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD97099.1 - 8e-05 21.9 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGD97099.1 - 0.00012 21.3 0.1 0.00029 20.1 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EGD97099.1 - 0.0041 16.9 0.2 2.4 7.9 0.0 2.9 1 1 1 2 2 2 2 Dynamin family PduV-EutP PF10662.4 EGD97099.1 - 0.0072 15.8 0.1 0.019 14.4 0.1 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 EGD97099.1 - 0.016 14.5 0.2 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 Ras family FeoB_N PF02421.13 EGD97099.1 - 0.017 14.3 0.5 0.055 12.7 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU_D4 PF14578.1 EGD97099.1 - 0.067 12.8 4.3 0.48 10.1 0.1 3.4 3 1 0 3 3 3 0 Elongation factor Tu domain 4 Mito_carr PF00153.22 EGD97100.1 - 2.1e-58 194.0 0.1 3.9e-21 74.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.13 EGD97101.1 - 0.04 13.8 1.7 0.04 13.8 1.2 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain IMS_C PF11799.3 EGD97101.1 - 0.1 12.4 0.1 0.43 10.5 0.0 2.0 1 1 1 2 2 2 0 impB/mucB/samB family C-terminal domain Ribosomal_S2 PF00318.15 EGD97102.1 - 2.4e-49 167.4 0.0 5.7e-49 166.2 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S2 Gly_transf_sug PF04488.10 EGD97103.1 - 7.8e-12 45.5 0.2 1.7e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Acyl_transf_3 PF01757.17 EGD97105.1 - 1.3e-39 135.9 31.7 1.6e-39 135.7 22.0 1.1 1 0 0 1 1 1 1 Acyltransferase family Rick_17kDa_Anti PF05433.10 EGD97107.1 - 0.0027 17.3 15.8 0.0027 17.3 11.0 2.7 3 0 0 3 3 3 1 Glycine zipper 2TM domain SURF6 PF04935.7 EGD97109.1 - 8.1e-51 172.3 35.3 8.1e-51 172.3 24.5 4.1 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 EGD97109.1 - 1.1e-22 79.8 0.6 1.1e-22 79.8 0.4 8.4 6 2 0 7 7 7 1 60S ribosome biogenesis protein Rrp14 Fer4 PF00037.22 EGD97110.1 - 1.3e-13 49.8 16.5 5e-08 32.2 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EGD97110.1 - 1.1e-11 44.9 10.4 1.7e-11 44.2 7.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EGD97110.1 - 4.6e-10 40.1 7.2 0.0002 22.0 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EGD97110.1 - 2.4e-09 36.8 22.1 8.4e-08 31.8 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGD97110.1 - 2.6e-09 37.2 10.8 4.4e-09 36.4 7.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EGD97110.1 - 2e-08 33.9 21.9 6.1e-06 26.0 8.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGD97110.1 - 1.2e-07 31.2 14.7 0.00041 20.0 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EGD97110.1 - 1.2e-07 31.6 20.3 2.9e-05 24.0 7.9 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 EGD97110.1 - 2.3e-07 30.3 17.1 0.0012 18.6 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EGD97110.1 - 4.7e-06 26.4 12.7 0.00055 20.0 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EGD97110.1 - 9.8e-06 25.8 10.0 0.0011 19.2 7.7 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGD97110.1 - 6.7e-05 23.2 9.8 0.015 15.7 0.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EGD97110.1 - 0.0092 16.3 15.4 0.28 11.5 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EGD97110.1 - 0.017 15.7 13.5 0.2 12.2 1.0 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EGD97110.1 - 0.065 13.8 16.9 0.15 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EGD97110.1 - 0.14 12.2 4.9 0.29 11.2 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PCDO_beta_N PF12391.3 EGD97110.1 - 1.5 8.2 6.0 0.98 8.9 1.0 2.4 2 0 0 2 2 2 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal PP-binding PF00550.20 EGD97111.1 - 2.9e-11 43.4 0.4 4.5e-11 42.8 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EGD97111.1 - 5.5e-05 23.1 0.1 7.9e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EGD97111.1 - 0.0025 17.8 0.3 0.0039 17.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) GPP34 PF05719.6 EGD97112.1 - 1.4e-64 217.9 0.3 1.8e-64 217.5 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) ADH_zinc_N_2 PF13602.1 EGD97113.1 - 1.1e-21 78.0 0.0 2.1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD97113.1 - 0.002 17.8 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD97113.1 - 0.0044 16.5 0.0 0.0074 15.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2183 PF09949.4 EGD97114.1 - 6e-30 103.1 0.0 1.9e-29 101.5 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Myosin_tail_1 PF01576.14 EGD97115.1 - 0.032 11.9 3.3 0.079 10.6 0.0 2.0 2 0 0 2 2 2 0 Myosin tail CBS PF00571.23 EGD97118.1 - 8.6e-23 79.8 0.2 0.00028 20.6 0.0 5.4 5 0 0 5 5 5 5 CBS domain GCS PF03074.11 EGD97119.1 - 5.3e-154 512.7 0.0 8.8e-153 508.7 0.0 2.0 1 1 0 1 1 1 1 Glutamate-cysteine ligase UPF0278 PF08745.6 EGD97119.1 - 0.041 13.1 0.1 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 UPF0278 family DUF1560 PF07597.6 EGD97119.1 - 0.1 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) NDUF_B7 PF05676.8 EGD97120.1 - 2.4e-32 110.1 5.0 2.9e-32 109.8 3.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EGD97120.1 - 0.022 14.5 2.2 0.033 13.9 1.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ank_2 PF12796.2 EGD97121.1 - 8.3e-13 48.5 0.1 3.1e-09 37.0 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGD97121.1 - 1.4e-12 46.7 0.3 3.7e-10 39.1 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EGD97121.1 - 8.8e-10 38.5 0.7 3.7e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGD97121.1 - 3.2e-09 37.0 0.1 1.4e-06 28.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD97121.1 - 4.8e-09 35.5 0.1 2.9e-06 26.9 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.8 EGD97121.1 - 9.3e-05 22.0 0.1 0.00098 18.7 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain HALZ PF02183.13 EGD97121.1 - 1.9 8.2 4.9 11 5.8 0.5 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1510 PF07423.6 EGD97122.1 - 0.029 13.7 8.6 0.038 13.3 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4192 PF13830.1 EGD97122.1 - 0.33 10.5 3.4 0.43 10.1 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF1212 PF06738.7 EGD97125.1 - 4.6e-48 163.2 9.3 7.4e-45 152.7 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EGD97125.1 - 1.5e-26 92.8 32.5 5.3e-26 91.0 12.3 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF3815) Gag_spuma PF03276.9 EGD97128.1 - 3.3 5.9 6.4 4.2 5.5 4.4 1.0 1 0 0 1 1 1 0 Spumavirus gag protein PS_Dcarbxylase PF02666.10 EGD97129.1 - 4.7e-50 169.6 0.0 7.2e-50 169.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EGD97129.1 - 8.9e-33 111.9 0.2 6.3e-16 58.0 0.0 2.7 2 0 0 2 2 2 2 C2 domain EF-hand_5 PF13202.1 EGD97129.1 - 0.013 14.8 0.0 0.037 13.3 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 EGD97129.1 - 0.028 13.7 0.0 0.088 12.1 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 EGD97129.1 - 0.073 13.2 0.2 0.23 11.5 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain pair SprA-related PF12118.3 EGD97129.1 - 0.14 11.4 8.3 0.074 12.3 0.7 2.2 2 0 0 2 2 2 0 SprA-related family GATA PF00320.22 EGD97131.1 - 9.8e-13 47.2 0.7 2.1e-12 46.1 0.5 1.6 1 0 0 1 1 1 1 GATA zinc finger Spo12 PF05032.7 EGD97133.1 - 0.14 11.8 0.2 0.32 10.6 0.1 1.6 2 0 0 2 2 2 0 Spo12 family Macro PF01661.16 EGD97135.1 - 3.5e-33 113.9 0.0 6.4e-33 113.1 0.0 1.4 1 0 0 1 1 1 1 Macro domain Ank_2 PF12796.2 EGD97137.1 - 3.6e-12 46.4 0.2 4.8e-11 42.8 0.1 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGD97137.1 - 1.9e-10 40.0 0.4 4.2e-05 23.1 0.0 3.8 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EGD97137.1 - 6.1e-08 32.1 3.0 0.00058 19.8 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EGD97137.1 - 1e-05 25.8 0.2 2.9e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD97137.1 - 2.2e-05 24.5 0.1 2.2e-05 24.5 0.0 3.3 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Peptidase_S24 PF00717.18 EGD97138.1 - 0.00015 21.2 0.1 0.00083 18.9 0.1 2.1 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EGD97138.1 - 0.035 13.6 0.0 1.4 8.4 0.0 2.3 1 1 0 2 2 2 0 Signal peptidase, peptidase S26 AMP-binding PF00501.23 EGD97139.1 - 1.2e-95 320.3 0.0 2.2e-95 319.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EGD97139.1 - 3.6e-86 288.7 0.0 6.1e-86 288.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGD97139.1 - 8.4e-67 225.7 1.1 2.5e-66 224.2 1.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 EGD97139.1 - 3.1e-59 199.6 0.5 5.9e-58 195.5 0.1 3.1 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EGD97139.1 - 5.5e-54 182.5 0.2 5.6e-51 172.7 0.1 3.2 3 0 0 3 3 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 EGD97139.1 - 8.4e-45 152.6 0.0 9.1e-44 149.2 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGD97139.1 - 5.1e-40 136.0 0.5 1.5e-39 134.5 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EGD97139.1 - 7.8e-24 83.7 0.0 1.2e-12 47.8 0.0 3.3 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD97139.1 - 1.7e-12 48.1 0.0 8e-12 45.9 0.0 2.3 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EGD97139.1 - 6.2e-12 45.4 0.0 1e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD97139.1 - 2.8e-06 26.2 0.0 0.019 13.6 0.0 2.5 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EGD97139.1 - 7.5e-06 25.0 0.0 0.11 11.4 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGD97139.1 - 0.0002 21.4 0.8 0.036 14.0 0.0 3.1 3 0 0 3 3 3 1 NADH(P)-binding Thiolase_N PF00108.18 EGD97139.1 - 0.00065 18.7 0.3 0.0027 16.7 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain NmrA PF05368.8 EGD97139.1 - 0.029 13.6 0.4 0.1 11.8 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family PhyH PF05721.8 EGD97140.1 - 1.2e-18 67.9 0.0 2e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aminotran_1_2 PF00155.16 EGD97141.1 - 2.6e-18 66.1 0.0 3.3e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGD97141.1 - 0.013 14.2 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGD97141.1 - 0.2 10.6 0.2 1.6 7.7 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family NmrA PF05368.8 EGD97142.1 - 3.5e-12 46.0 0.0 8.5e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD97142.1 - 1.3e-08 35.0 0.1 4.1e-08 33.4 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGD97142.1 - 0.00011 21.7 0.0 0.00071 19.0 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EGD97142.1 - 0.00022 20.9 0.4 0.00036 20.2 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGD97142.1 - 0.0028 17.5 0.7 0.0053 16.6 0.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase GARS_N PF02844.10 EGD97142.1 - 0.051 14.0 0.1 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Sigma70_r1_1 PF03979.9 EGD97142.1 - 0.14 12.1 3.1 7.7 6.5 0.0 2.6 2 1 1 3 3 3 0 Sigma-70 factor, region 1.1 CUE PF02845.11 EGD97142.1 - 0.15 11.5 0.3 19 4.8 0.1 2.5 2 0 0 2 2 2 0 CUE domain AA_permease_2 PF13520.1 EGD97143.1 - 6e-33 114.0 53.9 7.4e-33 113.7 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD97143.1 - 8.2e-10 37.6 47.2 1e-09 37.2 32.7 1.1 1 0 0 1 1 1 1 Amino acid permease Tweety PF04906.8 EGD97143.1 - 0.24 9.7 3.2 0.18 10.2 0.6 2.0 2 0 0 2 2 2 0 Tweety PhyH PF05721.8 EGD97144.1 - 4.9e-22 79.0 0.0 6.2e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EGD97144.1 - 0.027 12.9 0.0 0.039 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Ank PF00023.25 EGD97145.1 - 7.3e-13 47.6 0.2 3.8e-07 29.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EGD97145.1 - 7.1e-12 45.5 0.0 4e-11 43.1 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGD97145.1 - 3.5e-11 42.2 0.1 7.4e-05 22.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGD97145.1 - 5.5e-11 42.6 0.5 1.3e-07 31.9 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD97145.1 - 9e-10 38.4 0.3 0.00027 21.0 0.1 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) MAGE PF01454.14 EGD97146.1 - 1.5e-42 145.1 0.0 2e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 MAGE family Xan_ur_permease PF00860.15 EGD97147.1 - 4.7e-21 74.7 26.0 4.1e-20 71.6 17.9 2.1 1 1 0 1 1 1 1 Permease family Sulfate_transp PF00916.15 EGD97147.1 - 2.2e-05 23.6 2.6 2.2e-05 23.6 1.8 2.3 1 1 2 3 3 3 1 Sulfate transporter family DUF973 PF06157.6 EGD97147.1 - 0.0069 15.3 0.7 0.014 14.4 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF973) Pal1 PF08316.6 EGD97148.1 - 7.8e-49 165.7 1.0 7.8e-49 165.7 0.7 2.3 2 0 0 2 2 2 1 Pal1 cell morphology protein Med31 PF05669.7 EGD97149.1 - 1.2e-27 95.6 0.0 1.4e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 SOH1 Fmp27_WPPW PF10359.4 EGD97149.1 - 0.0024 16.3 0.1 0.0031 15.9 0.1 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Tcf25 PF04910.9 EGD97149.1 - 0.0039 16.1 0.1 0.0041 16.1 0.1 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Aldolase_II PF00596.16 EGD97151.1 - 6.9e-44 149.6 0.2 8.8e-44 149.3 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PHD PF00628.24 EGD97153.1 - 1.4e-09 37.4 5.3 3e-09 36.4 3.7 1.5 1 0 0 1 1 1 1 PHD-finger Choline_kinase PF01633.15 EGD97153.1 - 0.049 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SRP-alpha_N PF04086.8 EGD97153.1 - 0.2 10.9 9.5 0.37 10.1 6.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Fungal_trans PF04082.13 EGD97154.1 - 3.2e-31 108.1 0.1 6e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD97154.1 - 5.7e-11 42.1 13.4 1.1e-10 41.2 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EGD97154.1 - 0.049 13.5 0.4 0.18 11.7 0.3 1.9 1 0 0 1 1 1 0 Gal4-like dimerisation domain Pkinase PF00069.20 EGD97155.1 - 4.7e-22 78.3 0.0 1.4e-21 76.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97155.1 - 0.0017 17.5 0.0 0.67 8.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_trans_2_3 PF13632.1 EGD97156.1 - 0.055 13.1 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DUF2413 PF10310.4 EGD97157.1 - 0.13 11.0 6.4 0.17 10.6 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Daxx PF03344.10 EGD97157.1 - 0.37 9.2 6.8 0.44 8.9 4.7 1.0 1 0 0 1 1 1 0 Daxx Family zf-H2C2_2 PF13465.1 EGD97158.1 - 2.3e-05 24.4 3.3 2.3e-05 24.4 2.3 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGD97158.1 - 3.6e-05 23.8 2.7 3.6e-05 23.8 1.9 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD97158.1 - 0.0019 18.4 0.7 0.0019 18.4 0.5 4.0 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD97158.1 - 0.0042 17.1 0.7 0.0042 17.1 0.5 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Fork_head PF00250.13 EGD97159.1 - 2.3e-36 123.6 2.1 5e-36 122.6 1.5 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EGD97159.1 - 1.1e-08 35.0 0.0 7.8e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 FHA domain DUF566 PF04484.7 EGD97160.1 - 0.9 8.9 3.3 1.5 8.2 2.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF2011 PF09428.5 EGD97161.1 - 0.68 9.8 7.6 0.82 9.5 5.2 1.5 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) Ribosomal_L24e PF01246.15 EGD97162.1 - 1.5e-27 95.2 3.0 3.6e-27 93.9 2.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e zf-C2HC5 PF06221.8 EGD97162.1 - 0.0094 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DnaJ PF00226.26 EGD97163.1 - 1.1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EGD97163.1 - 4.2e-06 26.5 0.2 9.2e-06 25.4 0.2 1.6 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 EGD97163.1 - 0.008 15.4 0.9 0.008 15.4 0.6 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3918) Pkinase PF00069.20 EGD97164.1 - 7e-63 212.1 0.0 9.5e-63 211.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97164.1 - 1.8e-26 92.7 0.0 2.8e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD97164.1 - 0.074 12.7 0.1 0.074 12.7 0.1 2.5 2 2 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EGD97164.1 - 0.088 11.8 0.1 0.24 10.4 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family G_glu_transpept PF01019.16 EGD97165.1 - 8.8e-147 489.6 0.0 1e-146 489.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase p450 PF00067.17 EGD97166.1 - 1.9e-28 99.2 0.0 7.2e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 Clusterin PF01093.12 EGD97168.1 - 0.017 13.9 1.5 0.028 13.2 1.0 1.3 1 0 0 1 1 1 0 Clusterin zf-C2H2_4 PF13894.1 EGD97169.1 - 0.078 13.3 0.3 0.25 11.7 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger ICL PF00463.16 EGD97170.1 - 1.7e-283 940.6 1.6 1.9e-283 940.4 1.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EGD97170.1 - 3.1e-12 46.2 0.0 9.5e-12 44.6 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.13 EGD97171.1 - 8.4e-189 628.4 0.1 1e-188 628.2 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EGD97171.1 - 3.4e-17 61.4 0.1 5.5e-17 60.7 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RHH_4 PF13467.1 EGD97171.1 - 0.11 12.3 0.0 2.7 7.9 0.0 2.7 3 0 0 3 3 3 0 Ribbon-helix-helix domain DUF4024 PF13216.1 EGD97171.1 - 0.12 12.2 0.3 0.22 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) adh_short PF00106.20 EGD97172.1 - 1.8e-26 93.0 0.0 2.9e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD97172.1 - 2.1e-26 93.1 0.0 2.6e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD97172.1 - 1.4e-07 31.3 0.0 2e-07 30.8 0.0 1.3 1 1 0 1 1 1 1 KR domain OTU PF02338.14 EGD97173.1 - 2.9e-16 60.1 0.3 1.6e-15 57.7 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGD97173.1 - 6.3e-07 29.0 0.4 0.00086 18.7 0.0 2.7 2 1 1 3 3 3 2 Peptidase C65 Otubain DUF3275 PF11679.3 EGD97173.1 - 0.61 9.6 4.2 0.68 9.5 2.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) RR_TM4-6 PF06459.7 EGD97173.1 - 3.6 7.4 10.1 0.66 9.8 4.4 1.6 1 1 1 2 2 2 0 Ryanodine Receptor TM 4-6 TPMT PF05724.6 EGD97174.1 - 7.2e-29 100.7 0.1 5.2e-28 97.9 0.1 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 EGD97174.1 - 8.6e-06 25.4 0.0 3.8e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD97174.1 - 0.00012 22.4 0.0 0.0002 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD97174.1 - 0.0012 18.8 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD97174.1 - 0.0075 16.6 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD97174.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.7 EGD97174.1 - 0.054 12.4 0.0 0.078 11.9 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein TehB PF03848.9 EGD97174.1 - 0.079 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MFS_1 PF07690.11 EGD97175.1 - 7.8e-48 162.9 39.1 2.6e-38 131.6 17.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD97175.1 - 8e-07 27.9 11.4 8e-07 27.9 7.9 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EGD97175.1 - 0.0054 14.8 10.8 0.51 8.3 0.2 3.6 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family HC2 PF07382.6 EGD97176.1 - 2.2e-11 44.0 1.8 2.2e-11 44.0 1.3 5.7 4 2 0 5 5 5 2 Histone H1-like nucleoprotein HC2 Aldedh PF00171.17 EGD97177.1 - 3.1e-83 279.6 0.0 3.7e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adap_comp_sub PF00928.16 EGD97178.1 - 6.8e-53 179.4 0.0 1.3e-52 178.4 0.0 1.5 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGD97178.1 - 0.00026 20.7 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4588 PF15251.1 EGD97180.1 - 8.7e-05 22.5 9.8 0.00032 20.7 6.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) DUF566 PF04484.7 EGD97180.1 - 9.2 5.6 7.8 15 4.9 5.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) SNF2_N PF00176.18 EGD97181.1 - 1.4e-81 273.6 0.3 2.2e-81 272.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EGD97181.1 - 1.2e-44 150.8 1.2 1.2e-44 150.8 0.9 2.2 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 EGD97181.1 - 6.1e-28 97.4 4.0 6.1e-28 97.4 2.7 4.1 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EGD97181.1 - 1.2e-14 53.9 0.0 3.6e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD97181.1 - 1.3e-08 34.8 0.1 2.8e-07 30.5 0.0 3.3 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EGD97181.1 - 1.9e-07 30.2 0.0 4.8e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EGD97181.1 - 4.7e-06 26.1 0.0 1.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EGD97181.1 - 0.0098 15.7 0.7 0.072 12.9 0.1 2.8 3 0 0 3 3 3 1 AAA domain DEAD_2 PF06733.10 EGD97181.1 - 0.02 14.2 0.1 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 SpoU_methylase PF00588.14 EGD97182.1 - 1.3e-25 89.9 0.0 2.9e-25 88.8 0.0 1.6 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EGD97182.1 - 2.3e-07 30.9 0.0 4.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.1 EGD97183.1 - 1.5e-71 239.2 10.4 3.6e-71 238.0 7.2 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EGD97183.1 - 1.1e-34 119.6 1.6 1.7e-34 118.9 1.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD97183.1 - 6.2e-13 48.4 0.0 1.8e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGD97183.1 - 9.2e-12 44.3 3.4 2.4e-11 42.9 2.4 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 EGD97183.1 - 7.4e-07 28.7 1.8 0.025 14.2 0.2 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EGD97183.1 - 0.00011 21.8 2.9 0.00011 21.8 2.0 3.8 3 1 0 3 3 3 1 PHD-finger DEAD_2 PF06733.10 EGD97183.1 - 0.0044 16.4 0.0 0.014 14.8 0.0 1.9 1 0 0 1 1 1 1 DEAD_2 SnAC PF14619.1 EGD97183.1 - 0.057 13.5 5.0 0.27 11.4 1.0 3.5 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex HMG-CoA_red PF00368.13 EGD97184.1 - 9.6e-153 508.2 9.6 1.2e-152 507.8 6.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EGD97184.1 - 1.3e-48 164.5 0.0 2.8e-48 163.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EGD97184.1 - 3.1e-13 49.4 4.4 3.2e-12 46.1 3.1 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EGD97184.1 - 6.6e-06 24.3 2.0 6.6e-06 24.3 1.4 1.3 2 0 0 2 2 2 1 Patched family CVNH PF08881.5 EGD97185.1 - 8.1e-28 96.7 0.5 9e-28 96.5 0.4 1.0 1 0 0 1 1 1 1 CVNH domain PBP1_TM PF14812.1 EGD97186.1 - 0.018 15.3 4.6 0.2 12.0 2.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GIT_SHD PF08518.6 EGD97187.1 - 3e-22 77.6 6.7 8.1e-13 47.4 0.6 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT APG6 PF04111.7 EGD97187.1 - 0.0045 16.0 8.0 0.0045 16.0 5.6 2.6 1 1 1 2 2 2 2 Autophagy protein Apg6 IncA PF04156.9 EGD97187.1 - 1.2 8.6 34.6 0.16 11.5 4.7 3.3 3 0 0 3 3 3 0 IncA protein Pro_isomerase PF00160.16 EGD97188.1 - 3.1e-36 124.9 0.3 4.2e-36 124.5 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CfAFP PF05264.6 EGD97188.1 - 0.06 13.1 0.3 0.094 12.4 0.2 1.3 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) RNase_PH PF01138.16 EGD97189.1 - 4.9e-29 101.3 0.2 1e-28 100.2 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 SNF2_N PF00176.18 EGD97190.1 - 1.2e-55 188.3 0.0 1.9e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EGD97190.1 - 5.2e-27 93.5 0.4 1.4e-26 92.1 0.3 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EGD97190.1 - 6.1e-14 51.6 0.0 2.4e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD97190.1 - 7.9e-05 22.5 1.2 0.00077 19.3 0.0 3.1 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGD97190.1 - 0.00034 20.1 0.0 0.00078 18.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ssu72 PF04722.8 EGD97191.1 - 7.6e-84 279.8 0.0 8.9e-84 279.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein PyrI_C PF02748.10 EGD97192.1 - 0.011 15.1 0.5 2 7.8 0.1 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CCHC PF00098.18 EGD97192.1 - 0.02 14.7 2.7 0.049 13.5 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle RAP1 PF07218.6 EGD97192.1 - 0.064 11.3 3.2 0.091 10.8 2.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-BED PF02892.10 EGD97192.1 - 0.12 12.1 3.8 6.3 6.6 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-CHCC PF10276.4 EGD97192.1 - 0.17 11.7 4.6 1.3 8.9 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger domain Acyl-CoA_dh_1 PF00441.19 EGD97193.1 - 4.9e-19 68.9 0.1 2.9e-18 66.4 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGD97193.1 - 1.4e-05 24.5 0.8 0.0001 21.7 0.6 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Oxysterol_BP PF01237.13 EGD97194.1 - 7.8e-88 294.3 0.0 9.9e-88 293.9 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF3605 PF12239.3 EGD97195.1 - 1.3e-54 184.3 4.9 9.3e-54 181.5 3.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) DUF4116 PF13475.1 EGD97195.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Isochorismatase PF00857.15 EGD97196.1 - 1.2e-25 90.4 0.0 1.7e-24 86.6 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family Hist_deacetyl PF00850.14 EGD97197.1 - 4.2e-76 256.2 0.2 6e-76 255.7 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.2 EGD97198.1 - 5.5e-24 84.4 3.6 9.3e-24 83.7 2.5 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EGD97198.1 - 1.9e-08 33.8 9.9 3.4e-08 33.0 6.9 1.4 1 0 0 1 1 1 1 PHD-finger DUF4200 PF13863.1 EGD97198.1 - 0.29 11.0 1.9 2.5 8.0 1.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) CCDC144C PF14915.1 EGD97198.1 - 7.5 5.3 8.7 0.089 11.6 0.8 1.5 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region RNA_pol_Rpc34 PF05158.7 EGD97199.1 - 2.3e-102 342.5 0.0 2.8e-102 342.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit PadR PF03551.9 EGD97199.1 - 0.076 12.7 0.1 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Rrf2 PF02082.15 EGD97199.1 - 0.08 13.0 0.1 0.87 9.7 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator TPR_11 PF13414.1 EGD97200.1 - 1.9e-50 168.3 27.7 2e-15 56.1 0.7 6.5 5 1 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 EGD97200.1 - 6.1e-38 126.9 25.8 1.7e-05 24.1 0.0 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EGD97200.1 - 6.5e-30 100.6 25.3 0.00019 21.0 0.1 10.0 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 EGD97200.1 - 5.6e-16 58.2 15.2 7.3e-08 32.2 0.2 5.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD97200.1 - 2.4e-15 56.7 16.9 0.0012 19.4 0.2 6.9 3 3 4 7 7 7 7 Tetratricopeptide repeat TPR_19 PF14559.1 EGD97200.1 - 6e-13 48.9 22.9 0.00063 20.0 0.2 6.4 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGD97200.1 - 2.7e-12 46.1 22.2 0.31 11.7 0.2 10.1 7 2 4 11 11 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGD97200.1 - 4.6e-11 41.6 15.6 0.052 13.3 0.2 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGD97200.1 - 2.3e-10 39.8 10.7 0.019 15.0 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGD97200.1 - 1.6e-07 31.0 9.4 0.0071 16.1 0.3 5.4 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD97200.1 - 1.3e-06 27.7 13.8 0.033 13.9 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD97200.1 - 0.00031 20.7 14.7 0.054 13.6 0.7 3.9 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EGD97200.1 - 0.3 11.6 22.7 3.4 8.3 0.0 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat VirionAssem_T7 PF11653.3 EGD97200.1 - 9.2 7.0 9.0 11 6.8 3.8 2.6 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein SHNi-TPR PF10516.4 EGD97200.1 - 10 5.4 10.0 12 5.2 0.1 5.3 7 0 0 7 7 7 0 SHNi-TPR C2 PF00168.25 EGD97201.1 - 1.2e-63 210.9 2.1 2.9e-17 62.2 0.0 5.6 5 0 0 5 5 5 5 C2 domain RRM_1 PF00076.17 EGD97203.1 - 1.6e-16 59.6 0.0 5.4e-12 45.1 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD97203.1 - 1.6e-14 53.5 0.0 1.1e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD97203.1 - 6e-14 51.6 0.0 5.3e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGD97203.1 - 0.00082 19.0 0.0 0.12 12.1 0.0 2.9 2 1 0 2 2 2 1 Limkain b1 UDPGP PF01704.13 EGD97204.1 - 5.3e-181 601.7 0.1 6.2e-181 601.4 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.8 EGD97204.1 - 0.064 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Pilus assembly protein, PilO zf-CCCH PF00642.19 EGD97206.1 - 8.1e-09 34.9 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EGD97206.1 - 5.2e-06 26.2 0.0 9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD97206.1 - 0.0003 20.3 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD97206.1 - 0.036 14.0 0.0 0.09 12.7 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4185 PF13810.1 EGD97207.1 - 4.5e-05 22.5 0.5 6.7e-05 21.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Kelch_5 PF13854.1 EGD97207.1 - 0.036 14.0 0.5 0.22 11.5 0.0 2.5 3 0 0 3 3 3 0 Kelch motif RNA_pol_L_2 PF13656.1 EGD97207.1 - 0.095 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Amidase PF01425.16 EGD97208.1 - 3e-84 283.4 0.0 5.4e-84 282.5 0.0 1.4 1 1 0 1 1 1 1 Amidase SepZ PF06066.6 EGD97208.1 - 0.062 13.3 0.2 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 SepZ MFS_1 PF07690.11 EGD97209.1 - 3.4e-15 55.6 26.4 5.3e-15 54.9 17.6 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily PhyH PF05721.8 EGD97210.1 - 8e-30 104.4 0.0 1e-29 104.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HNH_2 PF13391.1 EGD97212.1 - 4.1e-16 58.5 0.0 7.2e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Epimerase PF01370.16 EGD97213.1 - 9.3e-07 28.5 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 EGD97214.1 - 1.3e-05 24.9 12.1 2.4e-05 24.1 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FYVE PF01363.16 EGD97216.1 - 4.5e-19 68.0 0.8 4.5e-19 68.0 0.6 3.2 4 0 0 4 4 4 1 FYVE zinc finger zf-RING_2 PF13639.1 EGD97216.1 - 1.1e-08 34.7 5.2 1.1e-08 34.7 3.6 3.4 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EGD97216.1 - 0.00064 19.7 2.6 0.00064 19.7 1.8 3.4 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGD97216.1 - 0.0028 17.2 4.1 0.0028 17.2 2.8 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 EGD97216.1 - 0.71 9.7 8.2 0.07 13.0 0.4 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Elf1 PF05129.8 EGD97216.1 - 5 6.8 8.0 1.2 8.9 0.8 2.9 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zf-C3HC4_2 PF13923.1 EGD97216.1 - 9.6 6.3 24.8 0.061 13.3 3.2 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) TRP PF06011.7 EGD97217.1 - 4.6e-90 302.3 26.7 1.6e-89 300.5 18.5 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGD97217.1 - 1.1e-13 51.3 0.1 1.8e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Strabismus PF06638.6 EGD97217.1 - 2.9 6.0 6.8 5 5.3 4.7 1.2 1 0 0 1 1 1 0 Strabismus protein Cys_Met_Meta_PP PF01053.15 EGD97220.1 - 1.1e-60 205.0 0.0 4.8e-60 202.8 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EGD97220.1 - 0.00093 18.0 0.0 0.0018 17.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DUF2073 PF09846.4 EGD97220.1 - 0.015 14.8 0.0 0.87 9.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) DegT_DnrJ_EryC1 PF01041.12 EGD97220.1 - 0.025 13.6 0.1 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EGD97220.1 - 0.055 12.4 0.0 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II ThiS PF02597.15 EGD97221.1 - 0.00075 19.8 0.0 0.007 16.7 0.0 1.9 1 1 0 1 1 1 1 ThiS family GFA PF04828.9 EGD97222.1 - 2.1e-21 75.6 0.7 2.1e-21 75.6 0.5 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EGD97222.1 - 4.5 7.0 8.9 6.7 6.5 0.1 3.5 2 1 0 2 2 2 0 Nudix N-terminal Zn_clus PF00172.13 EGD97223.1 - 1.5e-08 34.3 4.5 3e-08 33.4 3.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGD97223.1 - 6e-08 31.8 0.3 1.4e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 EGD97224.1 - 1.6e-26 92.7 26.9 2.3e-26 92.2 18.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGD97224.1 - 1.4e-25 90.2 0.3 4.2e-25 88.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EGD97224.1 - 5.2e-10 39.7 0.1 8.7e-08 32.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGD97224.1 - 2.3e-05 23.8 0.2 0.00046 19.6 0.0 2.4 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 EGD97224.1 - 2.5e-05 23.5 0.1 4.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EGD97224.1 - 3.1e-05 23.3 0.1 6.9e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EGD97224.1 - 0.00013 21.1 0.2 0.021 13.8 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.1 EGD97224.1 - 0.00014 21.9 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGD97224.1 - 0.00082 19.0 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EGD97224.1 - 0.0014 18.8 0.1 0.0086 16.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EGD97224.1 - 0.0018 18.4 0.0 0.028 14.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EGD97224.1 - 0.0034 16.3 0.0 0.007 15.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EGD97224.1 - 0.0035 16.8 0.2 0.0077 15.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGD97224.1 - 0.0048 17.7 0.0 0.011 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGD97224.1 - 0.0053 16.2 0.0 0.075 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain cobW PF02492.14 EGD97224.1 - 0.0054 16.2 0.1 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EGD97224.1 - 0.0088 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 EGD97224.1 - 0.0095 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGD97224.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGD97224.1 - 0.02 15.2 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGD97224.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.10 EGD97224.1 - 0.031 12.9 0.0 0.05 12.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 EGD97224.1 - 0.032 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGD97224.1 - 0.036 13.7 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 EGD97224.1 - 0.044 13.4 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 EGD97224.1 - 0.045 13.6 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 EGD97224.1 - 0.052 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EGD97224.1 - 0.075 13.2 0.0 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF2304 PF10066.4 EGD97224.1 - 0.095 12.5 4.1 0.38 10.6 2.9 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) ABC2_membrane_3 PF12698.2 EGD97224.1 - 0.15 11.0 23.8 0.28 10.1 16.5 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein MMR_HSR1 PF01926.18 EGD97224.1 - 0.16 11.9 0.3 0.39 10.6 0.2 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EGD97224.1 - 0.19 12.0 1.1 0.63 10.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EGD97224.1 - 0.7 8.2 5.3 0.43 8.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain tRNA-synt_2 PF00152.15 EGD97225.1 - 2.8e-102 341.9 0.0 3.9e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGD97225.1 - 5.5e-05 22.9 0.0 9.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EGD97225.1 - 0.0029 17.2 0.2 0.0074 15.8 0.1 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) LRRCT PF01463.19 EGD97226.1 - 0.18 12.1 0.7 13 6.4 0.0 2.8 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain PUD PF03714.9 EGD97227.1 - 0.024 14.7 3.7 0.24 11.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial pullanase-associated domain PEP_mutase PF13714.1 EGD97228.1 - 8.9e-67 224.7 0.9 1e-66 224.5 0.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ABC_tran PF00005.22 EGD97229.1 - 7.7e-49 165.5 0.0 1.5e-31 109.4 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGD97229.1 - 3.7e-32 111.8 32.2 1.9e-17 63.5 10.5 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EGD97229.1 - 2.4e-12 46.5 0.0 0.0028 16.8 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGD97229.1 - 7.1e-08 33.0 0.6 1.6e-05 25.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGD97229.1 - 4e-05 23.0 0.1 0.38 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EGD97229.1 - 5.1e-05 22.3 0.0 0.016 14.1 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 EGD97229.1 - 5.2e-05 23.3 0.4 0.067 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EGD97229.1 - 0.00014 21.3 4.3 0.048 13.1 0.1 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EGD97229.1 - 0.00024 21.2 0.0 1.2 9.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EGD97229.1 - 0.00028 20.0 0.0 0.78 8.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 EGD97229.1 - 0.00035 20.6 1.8 1.5 8.7 0.0 3.9 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EGD97229.1 - 0.00054 19.9 0.0 0.21 11.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EGD97229.1 - 0.003 17.0 0.1 2.9 7.2 0.1 2.6 2 1 0 2 2 2 2 AAA-like domain Miro PF08477.8 EGD97229.1 - 0.0032 17.9 0.1 4.8 7.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein Zeta_toxin PF06414.7 EGD97229.1 - 0.0038 16.3 0.2 0.82 8.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.12 EGD97229.1 - 0.023 14.5 5.3 0.6 9.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_17 PF13207.1 EGD97229.1 - 0.044 14.6 0.2 5.8 7.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGD97229.1 - 0.046 13.1 0.0 7.6 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EGD97229.1 - 0.049 13.0 0.0 2 7.7 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.1 EGD97229.1 - 0.059 12.9 0.3 14 5.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 EGD97229.1 - 0.11 11.4 0.0 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Methyltransf_32 PF13679.1 EGD97229.1 - 0.25 11.0 0.0 0.52 9.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PhoD PF09423.5 EGD97230.1 - 3.1e-158 527.0 0.6 3.6e-158 526.8 0.4 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase LigD_N PF13298.1 EGD97231.1 - 1.4e-25 89.4 0.1 3.2e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Sulf_transp PF04143.9 EGD97232.1 - 1.4e-12 47.4 25.1 1e-08 35.0 5.3 3.8 4 0 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 EGD97232.1 - 2.3e-09 36.7 0.3 2.3e-09 36.7 0.2 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4341) Peptidase_M28 PF04389.12 EGD97233.1 - 5.1e-33 114.2 0.0 7.5e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Rhodanese PF00581.15 EGD97236.1 - 8.2e-10 39.0 0.0 1.4e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain HTH_22 PF13309.1 EGD97236.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 HTH domain MutS_V PF00488.16 EGD97237.1 - 2e-79 266.3 0.0 3.2e-79 265.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGD97237.1 - 5.4e-52 176.5 0.1 1.2e-51 175.4 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGD97237.1 - 1.8e-33 114.9 0.1 9.5e-33 112.5 0.1 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EGD97237.1 - 3.5e-16 59.1 2.7 8.2e-16 57.9 1.9 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EGD97237.1 - 2.2e-13 50.4 0.0 7.7e-13 48.6 0.0 2.0 1 0 0 1 1 1 1 MutS domain II SPT6_acidic PF14632.1 EGD97237.1 - 0.00048 20.2 11.1 0.00048 20.2 7.7 3.2 2 1 1 3 3 3 1 Acidic N-terminal SPT6 AAA_23 PF13476.1 EGD97237.1 - 0.024 14.9 0.1 0.024 14.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 EGD97237.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EGD97237.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.3 3 0 0 3 3 3 0 AAA domain tRNA-synt_1b PF00579.20 EGD97238.1 - 3.6e-72 242.9 0.0 5.1e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Raffinose_syn PF05691.7 EGD97239.1 - 4.8e-53 179.8 1.1 1.1e-39 135.6 0.0 4.0 3 1 1 4 4 4 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 EGD97239.1 - 8e-06 24.7 0.7 1.7e-05 23.6 0.1 1.8 1 1 1 2 2 2 1 Melibiase DUF1697 PF08002.6 EGD97239.1 - 0.16 12.0 0.3 0.56 10.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1697) Aldedh PF00171.17 EGD97240.1 - 4.5e-163 542.8 0.4 5.1e-163 542.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_S11 PF00411.14 EGD97240.1 - 0.067 13.3 0.1 0.2 11.8 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S11 RRN9 PF10680.4 EGD97241.1 - 5.3e-19 67.7 0.1 1.4e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2_4 PF13894.1 EGD97241.1 - 0.17 12.3 1.5 0.37 11.2 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Pescadillo_N PF06732.6 EGD97242.1 - 1.1e-113 379.1 0.0 1.1e-113 379.1 0.0 2.5 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 EGD97242.1 - 6.8e-06 26.1 0.0 0.00013 22.0 0.0 2.8 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.8 EGD97243.1 - 9.6e-120 399.9 25.4 1.1e-119 399.7 17.6 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Acetyltransf_1 PF00583.19 EGD97244.1 - 1.7e-15 56.8 0.0 2.7e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD97244.1 - 9.9e-06 25.6 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD97244.1 - 2.2e-05 24.0 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGD97244.1 - 4.8e-05 23.4 0.0 7.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGD97244.1 - 7.1e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGD97244.1 - 0.0015 18.6 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HIG_1_N PF04588.8 EGD97245.1 - 2.1e-22 78.6 0.2 3.6e-22 77.8 0.2 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region OPA3 PF07047.7 EGD97245.1 - 0.059 13.1 0.4 0.096 12.4 0.3 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF2681 PF10883.3 EGD97245.1 - 0.064 13.4 1.4 0.11 12.6 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Peptidase_S15 PF02129.13 EGD97245.1 - 0.1 11.9 0.3 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PALP PF00291.20 EGD97246.1 - 7.6e-75 251.9 0.5 9.3e-75 251.6 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EGD97246.1 - 1.4e-43 146.3 0.0 5.7e-21 73.9 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.13 EGD97247.1 - 4.5e-20 71.3 9.8 7.3e-20 70.6 6.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 EGD97247.1 - 0.079 12.2 0.4 0.16 11.2 0.2 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family GTP_EFTU PF00009.22 EGD97248.1 - 8.8e-56 188.3 0.3 1.6e-55 187.4 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EGD97248.1 - 3e-32 110.3 0.0 6.2e-32 109.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EGD97248.1 - 9.3e-31 105.8 0.0 1.9e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EGD97248.1 - 2.9e-24 84.7 0.0 7.8e-24 83.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGD97248.1 - 3.1e-12 46.4 0.1 9.3e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.12 EGD97248.1 - 0.048 13.2 0.1 0.2 11.1 0.1 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Abhydrolase_6 PF12697.2 EGD97249.1 - 1.3e-13 51.3 0.1 2.7e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD97249.1 - 2.6e-13 49.9 0.0 6.3e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGD97249.1 - 3.1e-05 23.6 0.0 4.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EGD97249.1 - 0.00012 21.7 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 EGD97249.1 - 0.0014 17.4 0.0 0.0022 16.7 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 EGD97249.1 - 0.014 15.2 0.1 0.033 14.0 0.0 1.6 1 1 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 EGD97249.1 - 0.11 11.7 0.0 0.25 10.5 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family TLD PF07534.11 EGD97251.1 - 1.7e-20 73.4 0.0 3e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 TLD NMT_C PF02799.10 EGD97252.1 - 9.1e-77 256.7 0.2 1.4e-76 256.0 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EGD97252.1 - 1.1e-76 256.0 0.1 2.3e-76 254.9 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 EGD97252.1 - 4.6e-06 26.4 0.0 1.5e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGD97252.1 - 0.0043 17.2 0.0 0.014 15.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGD97252.1 - 0.071 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mur_ligase_M PF08245.7 EGD97253.1 - 1.3e-07 31.8 0.4 1.3e-06 28.6 0.3 2.6 1 1 0 1 1 1 1 Mur ligase middle domain Syja_N PF02383.13 EGD97254.1 - 1.3e-90 303.4 0.0 1.6e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain FUN14 PF04930.10 EGD97254.1 - 0.15 12.3 0.1 1.8 8.8 0.0 2.6 3 0 0 3 3 3 0 FUN14 family zf-CCCH PF00642.19 EGD97255.1 - 1.1e-16 60.1 25.4 8.7e-07 28.4 0.5 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CBM_1 PF00734.13 EGD97255.1 - 0.22 11.1 1.2 5.3 6.8 0.0 2.8 2 0 0 2 2 2 0 Fungal cellulose binding domain zf-C3H1 PF10650.4 EGD97255.1 - 0.35 10.3 6.7 1.9 8.0 0.3 3.2 2 0 0 2 2 2 0 Putative zinc-finger domain CC PF04942.9 EGD97255.1 - 1.3 8.9 0.1 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 CC domain Glyco_hydro_18 PF00704.23 EGD97256.1 - 9.6e-81 271.8 0.0 1.1e-80 271.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_75 PF07335.6 EGD97257.1 - 4.3e-21 75.4 0.0 5e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF3712 PF12505.3 EGD97258.1 - 7.4e-33 113.2 4.2 2e-32 111.8 1.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) ASFV_J13L PF05568.6 EGD97258.1 - 0.08 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Sel1 PF08238.7 EGD97259.1 - 3.3e-14 52.9 12.3 1.4e-05 25.5 2.4 4.4 4 0 0 4 4 4 3 Sel1 repeat Glyco_hydro_18 PF00704.23 EGD97260.1 - 3.5e-24 85.9 0.2 8.4e-23 81.3 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Syndecan PF01034.15 EGD97261.1 - 0.057 13.0 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 EGD97261.1 - 0.36 11.2 0.0 0.36 11.2 0.0 2.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TFIIA PF03153.8 EGD97261.1 - 1.3 8.8 19.7 1.7 8.4 13.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myc_target_1 PF15179.1 EGD97261.1 - 8.2 5.9 10.0 63 3.0 6.9 2.0 1 1 0 1 1 1 0 Myc target protein 1 F-box PF00646.28 EGD97262.1 - 0.0088 15.6 1.8 0.012 15.2 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EGD97262.1 - 0.011 15.3 1.5 0.038 13.7 0.1 2.6 3 0 0 3 3 3 0 F-box-like YrzO PF14142.1 EGD97262.1 - 2.1 8.0 4.0 4.5 6.9 2.8 1.5 1 0 0 1 1 1 0 YrzO-like protein DUF1761 PF08570.5 EGD97263.1 - 0.66 9.9 10.1 0.18 11.8 1.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1761) RseC_MucC PF04246.7 EGD97263.1 - 0.85 9.1 4.4 6.2 6.4 0.5 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PgaD PF13994.1 EGD97263.1 - 4.4 6.7 10.1 8.5 5.8 3.1 2.7 2 1 0 2 2 2 0 PgaD-like protein DUF1776 PF08643.5 EGD97264.1 - 6.6e-87 291.4 0.0 7.9e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) WLM PF08325.5 EGD97265.1 - 3.4e-60 203.1 0.1 4.8e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EGD97265.1 - 0.00013 20.9 1.4 0.00013 20.9 1.0 3.1 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF45 PF01863.12 EGD97265.1 - 0.0018 18.1 1.7 0.0035 17.1 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 EGD97265.1 - 0.0024 17.5 1.3 0.029 14.0 0.1 2.3 2 0 0 2 2 2 1 SprT-like family Peptidase_M54 PF07998.6 EGD97265.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 DUF955 PF06114.8 EGD97265.1 - 0.077 12.7 0.4 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF955) C1_1 PF00130.17 EGD97265.1 - 0.46 10.2 8.7 7.6 6.3 4.6 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 EGD97265.1 - 0.63 9.8 7.5 3 7.7 1.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.20 EGD97266.1 - 2.8e-23 82.4 0.0 3.7e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97266.1 - 1.3e-06 27.7 0.0 0.0014 17.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Regulator_TrmB PF11495.3 EGD97267.1 - 0.09 11.7 0.2 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Trp_DMAT PF11991.3 EGD97268.1 - 1.7e-102 343.2 0.0 2.1e-102 343.0 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF1394 PF07159.7 EGD97268.1 - 0.14 11.2 0.0 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1394) FAD_binding_3 PF01494.14 EGD97269.1 - 1.1e-12 47.6 2.6 6.3e-11 41.9 1.8 2.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGD97269.1 - 4.4e-07 29.1 2.8 0.0043 16.0 1.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD97269.1 - 7.6e-07 28.3 0.8 1.8e-06 27.1 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGD97269.1 - 5.1e-05 21.9 0.8 0.0016 16.9 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EGD97269.1 - 0.0002 21.3 0.9 0.00057 19.8 0.6 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGD97269.1 - 0.0053 15.6 1.4 0.0055 15.6 0.3 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EGD97269.1 - 0.0063 15.6 0.4 0.0097 15.0 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EGD97269.1 - 0.0063 16.0 0.3 0.012 15.1 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.1 EGD97269.1 - 0.016 15.2 0.3 0.048 13.6 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AMP-binding PF00501.23 EGD97270.1 - 4.1e-72 242.8 0.1 6.5e-37 126.9 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EGD97270.1 - 5.7e-65 219.1 0.0 3.9e-36 124.4 0.0 3.1 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EGD97270.1 - 6e-27 93.7 0.2 3e-12 46.6 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD97270.1 - 1.2e-05 26.1 0.0 6.6e-05 23.7 0.0 2.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GRIP PF01465.15 EGD97270.1 - 0.16 11.4 0.0 0.43 10.1 0.0 1.8 1 0 0 1 1 1 0 GRIP domain Ribonuclease PF00545.15 EGD97271.1 - 1.1e-18 67.1 0.1 1.7e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 ribonuclease WD40 PF00400.27 EGD97272.1 - 8.2e-66 215.7 24.4 1.1e-07 31.4 0.1 11.6 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 EGD97272.1 - 1.7e-20 72.9 0.0 3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EGD97272.1 - 3.3e-06 25.5 3.7 0.023 12.8 0.0 5.4 5 1 1 6 6 6 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 EGD97272.1 - 0.0047 15.2 0.1 0.099 10.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Utp13 PF08625.6 EGD97272.1 - 0.033 13.8 0.7 0.061 12.9 0.0 1.7 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain P34-Arc PF04045.9 EGD97273.1 - 2.1e-100 335.0 0.0 2.5e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EGD97273.1 - 0.019 14.3 0.0 0.071 12.4 0.0 1.9 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Hemerythrin PF01814.18 EGD97273.1 - 0.14 12.3 2.0 5.9 7.0 0.3 2.2 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF4294 PF14127.1 EGD97274.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) PP2C PF00481.16 EGD97275.1 - 3.7e-05 23.2 0.0 0.13 11.6 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGD97275.1 - 0.00033 20.1 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EGD97275.1 - 0.0015 18.2 0.1 0.0071 16.0 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Fcf1 PF04900.7 EGD97276.1 - 3.1e-13 49.6 1.5 1.1e-05 25.4 0.0 3.4 3 1 0 3 3 3 2 Fcf1 Cmc1 PF08583.5 EGD97277.1 - 5.5e-18 64.5 6.8 6.5e-18 64.2 4.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Prolamin_like PF05617.6 EGD97277.1 - 0.065 13.3 0.2 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 Prolamin-like Gemini_AL2 PF01440.11 EGD97277.1 - 0.068 13.2 0.1 0.082 13.0 0.1 1.1 1 0 0 1 1 1 0 Geminivirus AL2 protein NDUF_B7 PF05676.8 EGD97277.1 - 0.23 10.9 2.2 0.32 10.4 1.6 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.6 EGD97277.1 - 0.3 11.2 3.8 0.41 10.8 1.9 1.7 1 1 1 2 2 2 0 GCK domain HECA PF15353.1 EGD97277.1 - 0.34 10.6 4.6 0.51 10.0 3.2 1.3 1 1 0 1 1 1 0 Headcase protein family homologue WD40 PF00400.27 EGD97278.1 - 1.1e-22 79.0 16.0 1.7e-07 30.8 0.3 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGD97278.1 - 0.056 12.1 0.0 2.1 7.0 0.0 2.8 3 0 0 3 3 3 0 Nup133 N terminal like RRN3 PF05327.6 EGD97283.1 - 1.2e-161 538.6 0.0 1.2e-161 538.6 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_3 PF07859.8 EGD97284.1 - 7.3e-41 140.0 0.3 6.5e-31 107.5 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 EGD97284.1 - 8.6e-11 41.2 0.0 1.5e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EGD97284.1 - 0.0031 17.2 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGD97284.1 - 0.03 13.7 0.1 0.065 12.6 0.1 1.5 1 1 0 1 1 1 0 Putative esterase DUF2974 PF11187.3 EGD97284.1 - 0.03 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) ORC6 PF05460.8 EGD97284.1 - 1 8.4 4.9 1.4 7.9 3.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) tRNA-synt_2 PF00152.15 EGD97285.1 - 5.2e-76 255.5 0.0 7e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EGD97285.1 - 7.5e-19 67.6 0.0 1.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA-synt_2d PF01409.15 EGD97285.1 - 0.00034 19.9 0.1 0.65 9.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EGD97285.1 - 0.00041 20.1 0.0 0.00081 19.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ank_2 PF12796.2 EGD97286.1 - 2.3e-36 123.9 0.4 1.3e-11 44.6 0.0 5.3 1 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EGD97286.1 - 1.5e-27 94.0 4.1 0.0001 21.9 0.0 8.7 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.1 EGD97286.1 - 1.1e-21 74.7 0.9 0.0075 16.4 0.0 9.0 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.1 EGD97286.1 - 1.4e-17 63.6 3.4 0.00086 19.7 0.0 6.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD97286.1 - 1.3e-14 53.9 4.4 0.00016 21.7 0.0 7.5 5 3 4 9 9 9 4 Ankyrin repeats (many copies) DUF3447 PF11929.3 EGD97286.1 - 0.012 15.4 0.0 6.6 6.6 0.0 4.3 4 2 1 5 5 5 0 Domain of unknown function (DUF3447) HLH PF00010.21 EGD97288.1 - 4.8e-14 51.7 0.3 4.8e-14 51.7 0.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Septin PF00735.13 EGD97289.1 - 7.3e-10 38.3 0.0 5e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 Septin MCM PF00493.18 EGD97289.1 - 0.0074 15.1 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family Zeta_toxin PF06414.7 EGD97289.1 - 0.0092 15.0 0.1 0.037 13.1 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 EGD97289.1 - 0.045 14.5 0.0 0.1 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGD97289.1 - 0.056 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 EGD97289.1 - 0.085 13.3 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 EGD97289.1 - 0.089 12.7 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.16 EGD97289.1 - 0.096 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EGD97289.1 - 0.14 11.6 0.7 0.57 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EGD97289.1 - 0.15 11.9 0.0 0.44 10.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase PNRC PF15365.1 EGD97289.1 - 0.17 11.8 2.0 1.2 9.1 0.3 2.9 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator DUF815 PF05673.8 EGD97289.1 - 0.18 10.7 0.1 0.3 9.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HSP90 PF00183.13 EGD97290.1 - 8.7e-255 846.1 34.0 1.1e-254 845.8 23.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EGD97290.1 - 1.9e-11 43.6 0.1 3.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGD97290.1 - 3.3e-10 39.7 0.3 3.3e-10 39.7 0.2 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EGD97290.1 - 0.036 13.8 0.2 0.14 11.9 0.1 2.0 1 0 0 1 1 1 0 Tumour suppressor protein NTF2 PF02136.15 EGD97291.1 - 6.1e-22 78.2 0.2 1e-21 77.5 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EGD97291.1 - 1.2e-08 34.4 0.1 2.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD97291.1 - 1.9e-06 27.7 0.0 3.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD97291.1 - 6.4e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGD97291.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif TPR_11 PF13414.1 EGD97294.1 - 5.1e-07 29.2 3.5 0.031 13.9 0.1 4.9 4 1 1 5 5 5 3 TPR repeat TPR_17 PF13431.1 EGD97294.1 - 0.0067 16.5 3.7 1.9 8.8 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.13 EGD97294.1 - 0.012 15.4 1.0 0.9 9.4 0.1 3.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 EGD97294.1 - 0.02 14.8 1.8 4.2 7.3 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGD97294.1 - 0.029 15.0 8.0 1.1 10.0 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGD97294.1 - 0.054 13.1 0.2 7.6 6.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGD97294.1 - 0.12 12.3 0.7 9.5 6.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGD97294.1 - 0.12 13.0 8.6 6.6 7.6 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat BAF1_ABF1 PF04684.8 EGD97294.1 - 4.9 5.8 11.6 1.7 7.4 6.3 1.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Nnf1 PF03980.9 EGD97295.1 - 3.9e-31 107.2 1.7 3.9e-31 107.2 1.1 1.6 2 0 0 2 2 2 1 Nnf1 NYD-SP28 PF14772.1 EGD97295.1 - 0.0096 16.0 2.5 0.0096 16.0 1.8 1.7 2 0 0 2 2 2 1 Sperm tail Apolipoprotein PF01442.13 EGD97295.1 - 0.011 15.2 3.5 0.011 15.2 2.4 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Nup54 PF13874.1 EGD97295.1 - 0.014 15.0 3.1 0.036 13.7 2.1 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF1887 PF09002.6 EGD97295.1 - 0.025 12.9 0.5 0.034 12.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) DUF4515 PF14988.1 EGD97295.1 - 0.051 13.2 5.7 0.052 13.2 3.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) FlgN PF05130.7 EGD97295.1 - 0.058 13.6 7.2 0.15 12.2 5.0 1.8 1 1 1 2 2 2 0 FlgN protein DUF948 PF06103.6 EGD97295.1 - 0.063 13.1 0.8 0.18 11.7 0.6 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Ded_cyto PF06920.8 EGD97295.1 - 0.088 12.1 1.0 0.13 11.5 0.2 1.5 2 0 0 2 2 2 0 Dedicator of cytokinesis bZIP_1 PF00170.16 EGD97295.1 - 0.12 12.3 8.0 0.28 11.1 2.5 2.5 2 0 0 2 2 2 0 bZIP transcription factor Microtub_assoc PF07989.6 EGD97295.1 - 0.14 12.0 1.5 0.37 10.6 1.1 1.7 1 0 0 1 1 1 0 Microtubule associated Mod_r PF07200.8 EGD97295.1 - 0.23 11.3 5.6 0.25 11.2 3.0 1.7 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMPIT PF07851.8 EGD97295.1 - 0.39 9.7 1.5 0.5 9.3 1.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein LUC7 PF03194.10 EGD97295.1 - 2.2 7.7 6.3 2.5 7.5 4.0 1.3 1 1 0 1 1 1 0 LUC7 N_terminus FlaC_arch PF05377.6 EGD97295.1 - 5.2 7.0 7.6 2.7 7.9 1.3 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) KfrA_N PF11740.3 EGD97295.1 - 5.7 7.4 13.5 8.1 6.9 5.1 2.8 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term Pkinase PF00069.20 EGD97296.1 - 4e-77 258.8 0.7 4.7e-77 258.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97296.1 - 2.4e-37 128.4 0.0 4.3e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD97296.1 - 0.0004 19.4 0.3 0.0036 16.3 0.0 2.4 1 1 2 3 3 3 1 Kinase-like APH PF01636.18 EGD97296.1 - 0.049 13.3 0.1 0.049 13.3 0.1 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Zip PF02535.17 EGD97296.1 - 0.087 11.8 0.0 0.099 11.6 0.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Choline_kinase PF01633.15 EGD97296.1 - 0.14 11.6 0.1 0.14 11.6 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase SelP_N PF04592.9 EGD97296.1 - 0.15 11.4 9.6 0.24 10.7 6.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SIR2 PF02146.12 EGD97297.1 - 2.9e-30 105.2 0.0 5.2e-30 104.4 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Gemini_C4 PF01492.12 EGD97297.1 - 0.18 11.5 1.1 0.37 10.5 0.8 1.4 1 0 0 1 1 1 0 Geminivirus C4 protein AATase PF07247.7 EGD97298.1 - 4.5e-22 78.2 0.0 1.9e-21 76.2 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EGD97298.1 - 0.0013 17.6 0.0 0.017 13.9 0.0 2.3 2 1 0 2 2 2 1 Condensation domain MRP-L27 PF09809.4 EGD97298.1 - 0.029 13.9 0.0 0.074 12.6 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L27 Cation_efflux PF01545.16 EGD97299.1 - 1e-58 198.7 0.3 1.3e-58 198.3 0.2 1.1 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 EGD97299.1 - 0.031 12.8 0.2 0.047 12.2 0.1 1.2 1 0 0 1 1 1 0 Cation transport protein UreE_C PF05194.7 EGD97299.1 - 0.16 12.0 19.3 3.3 7.8 0.3 2.5 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain FGGY_C PF02782.11 EGD97300.1 - 9e-31 107.0 0.0 2.2e-30 105.7 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGD97300.1 - 2.4e-19 69.6 0.0 2.9e-11 43.1 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.7 EGD97301.1 - 1.2e-37 129.1 0.7 1.2e-37 129.1 0.5 2.7 3 0 0 3 3 3 1 Exportin 1-like protein SEO_N PF14576.1 EGD97301.1 - 0.015 14.6 0.2 0.037 13.2 0.1 1.6 1 0 0 1 1 1 0 Sieve element occlusion N-terminus HEAT PF02985.17 EGD97301.1 - 0.023 14.7 0.5 40 4.6 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Esterase PF00756.15 EGD97302.1 - 1.6e-55 188.2 0.0 2e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EGD97302.1 - 2.8e-06 27.1 0.0 3.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGD97302.1 - 1.7e-05 24.1 0.0 2.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGD97302.1 - 7.9e-05 22.6 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGD97302.1 - 0.00037 19.4 0.0 0.00059 18.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.4 EGD97302.1 - 0.00091 18.5 0.0 0.037 13.2 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 EGD97302.1 - 0.0047 16.5 0.0 0.086 12.3 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EGD97302.1 - 0.0074 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EGD97302.1 - 0.0082 15.7 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 EGD97302.1 - 0.017 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EGD97302.1 - 0.019 14.5 0.0 0.12 11.9 0.0 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 EGD97302.1 - 0.087 11.2 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_C50 PF03568.12 EGD97303.1 - 1.5e-114 382.6 0.0 4.1e-114 381.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.2 EGD97303.1 - 0.00016 20.9 0.0 0.002 17.3 0.0 2.6 1 1 0 1 1 1 1 CHAT domain TPR_16 PF13432.1 EGD97303.1 - 0.19 12.4 1.9 1.1e+02 3.6 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGD97303.1 - 0.35 10.8 11.6 3.4 7.6 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGD97303.1 - 9.9 6.3 11.4 40 4.4 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Muted PF14942.1 EGD97304.1 - 0.021 14.7 1.8 0.027 14.3 1.2 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Syntaxin PF00804.20 EGD97304.1 - 0.03 14.5 2.2 0.044 13.9 1.5 1.2 1 0 0 1 1 1 0 Syntaxin YtpI PF14007.1 EGD97307.1 - 0.034 14.0 1.3 0.097 12.6 0.9 1.7 1 0 0 1 1 1 0 YtpI-like protein Zn_clus PF00172.13 EGD97308.1 - 0.034 14.0 2.9 0.034 14.0 2.0 1.6 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGD97309.1 - 1.5e-23 82.9 0.4 2.9e-23 82.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 EGD97310.1 - 1.2e-69 235.0 0.0 1.5e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RAM PF15320.1 EGD97311.1 - 0.14 12.4 0.9 1.2 9.4 0.0 2.0 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Terpene_synth_C PF03936.11 EGD97312.1 - 4.4e-18 65.4 0.0 8.9e-18 64.4 0.0 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain MFS_1 PF07690.11 EGD97313.1 - 2.3e-34 118.6 26.4 8.6e-28 97.0 3.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD97313.1 - 2.5e-08 32.9 6.0 2.5e-08 32.9 4.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EGD97313.1 - 0.00026 19.5 2.8 0.00026 19.5 1.9 2.4 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 EGD97313.1 - 0.0084 14.3 0.7 0.0084 14.3 0.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EGD97313.1 - 0.028 14.2 0.1 0.028 14.2 0.1 3.3 2 1 2 4 4 4 0 MFS_1 like family TFR_dimer PF04253.10 EGD97314.1 - 7.9e-18 64.2 0.0 1.3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EGD97314.1 - 1e-15 57.9 0.0 2.6e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EGD97314.1 - 3.3e-06 26.7 0.0 7.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C2H2_4 PF13894.1 EGD97315.1 - 0.00071 19.7 2.0 0.055 13.8 0.0 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD97315.1 - 0.0018 18.4 4.7 0.028 14.7 0.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD97316.1 - 0.05 13.9 0.3 1.7 9.1 0.0 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger TFIIA PF03153.8 EGD97319.1 - 1.8e-80 271.6 28.5 4.5e-80 270.3 19.8 1.6 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-C2H2_4 PF13894.1 EGD97320.1 - 9.8e-06 25.5 8.6 0.028 14.7 0.4 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGD97320.1 - 0.00049 20.2 9.3 0.011 15.9 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGD97320.1 - 0.00093 19.2 1.8 0.14 12.3 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Macoilin PF09726.4 EGD97320.1 - 0.028 12.7 7.3 0.06 11.6 5.0 1.4 1 0 0 1 1 1 0 Transmembrane protein zf-C2H2 PF00096.21 EGD97320.1 - 0.044 14.1 0.8 0.044 14.1 0.6 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type Bap31 PF05529.7 EGD97321.1 - 1e-65 220.8 0.4 1.2e-65 220.6 0.3 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 EGD97321.1 - 0.0038 17.0 1.4 0.0065 16.2 1.0 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 EGD97321.1 - 0.0063 16.2 0.1 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Phage_GP20 PF06810.6 EGD97321.1 - 0.011 15.1 2.9 0.016 14.6 2.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Spc7 PF08317.6 EGD97321.1 - 0.017 13.8 0.4 0.026 13.2 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 EGD97321.1 - 0.059 12.8 2.9 0.071 12.6 0.2 2.4 2 1 0 2 2 2 0 Septum formation initiator DUF4349 PF14257.1 EGD97321.1 - 0.11 11.7 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2404 PF10296.4 EGD97322.1 - 0.00016 21.7 0.0 0.0067 16.5 0.0 2.3 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) Pkinase PF00069.20 EGD97326.1 - 5.2e-63 212.6 0.0 9.3e-63 211.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97326.1 - 8.8e-35 120.0 0.0 8.6e-30 103.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGD97326.1 - 5.4e-05 22.3 0.0 0.036 13.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EGD97326.1 - 0.0011 18.3 0.1 0.0028 17.0 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EGD97326.1 - 0.0021 17.8 0.4 0.0084 15.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD97326.1 - 0.061 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TSA PF03249.8 EGD97326.1 - 0.21 10.0 2.6 0.54 8.7 1.8 1.6 1 0 0 1 1 1 0 Type specific antigen Senescence PF06911.7 EGD97327.1 - 4.9e-47 159.9 1.4 6.9e-47 159.4 1.0 1.2 1 0 0 1 1 1 1 Senescence-associated protein Stanniocalcin PF03298.8 EGD97328.1 - 0.00024 20.2 0.1 0.00026 20.0 0.0 1.1 1 0 0 1 1 1 1 Stanniocalcin family Acyl-CoA_dh_1 PF00441.19 EGD97329.1 - 2.1e-39 135.0 6.5 3.4e-39 134.3 4.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGD97329.1 - 2.1e-29 102.3 1.1 6.5e-29 100.7 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGD97329.1 - 2e-17 62.4 0.0 4e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGD97329.1 - 1.3e-13 51.3 3.2 2.5e-13 50.4 2.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EGD97329.1 - 0.081 12.2 0.0 0.36 10.1 0.0 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.6 EGD97329.1 - 0.11 12.1 0.0 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 Staphylococcal AgrD protein MFS_1 PF07690.11 EGD97330.1 - 1.4e-24 86.5 39.2 4.8e-20 71.5 6.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EGD97330.1 - 8.5e-07 27.4 1.7 1.4e-06 26.7 1.2 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector GWT1 PF06423.7 EGD97332.1 - 1.5e-40 138.4 2.8 1.5e-40 138.4 2.0 2.2 2 0 0 2 2 2 1 GWT1 Amidase PF01425.16 EGD97333.1 - 8.9e-81 271.9 0.2 1.1e-80 271.6 0.1 1.1 1 0 0 1 1 1 1 Amidase DUF3827 PF12877.2 EGD97333.1 - 0.14 10.2 0.0 0.19 9.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Sec63 PF02889.11 EGD97334.1 - 8.1e-31 107.3 0.1 9.4e-29 100.6 0.1 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EGD97334.1 - 1.8e-12 46.8 0.2 3.6e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 EGD97334.1 - 0.038 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Peptidase_M24 PF00557.19 EGD97336.1 - 1.2e-51 175.2 0.0 1.6e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGD97336.1 - 1.2e-23 83.0 0.0 2.6e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain NAD_binding_8 PF13450.1 EGD97336.1 - 0.089 12.8 0.0 4.6 7.3 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SPRY PF00622.23 EGD97339.1 - 2.1e-17 63.3 0.0 3.9e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Zip PF02535.17 EGD97339.1 - 1.2 8.0 5.0 2 7.3 3.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PDEase_II PF02112.10 EGD97340.1 - 1.5e-56 191.8 0.0 6.4e-27 94.3 0.0 3.3 3 1 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EGD97340.1 - 1.2e-05 25.0 0.0 3.2e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGD97340.1 - 0.002 17.8 0.5 0.0048 16.5 0.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Fungal_trans PF04082.13 EGD97341.1 - 8.1e-11 41.2 0.3 1.4e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD97341.1 - 1.8e-10 40.5 10.4 1.8e-10 40.5 7.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EGD97342.1 - 8e-18 64.9 0.0 1.2e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD97342.1 - 9.7e-09 35.1 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD97342.1 - 0.0089 15.8 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Zn_clus PF00172.13 EGD97343.1 - 5.1e-09 35.9 11.8 1.4e-08 34.5 8.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DNL PF05180.7 EGD97343.1 - 2.4 7.9 7.7 7.8 6.2 0.0 2.9 3 0 0 3 3 3 0 DNL zinc finger ALO PF04030.9 EGD97344.1 - 1.3e-89 300.1 0.1 2e-89 299.5 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EGD97344.1 - 2.5e-31 107.9 0.2 4e-31 107.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4045 PF13254.1 EGD97345.1 - 5.8e-114 381.6 42.3 3.8e-71 240.5 21.7 5.6 3 3 3 6 6 6 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EGD97345.1 - 5.3e-06 26.0 0.0 0.018 14.7 0.0 2.9 2 0 0 2 2 2 2 Gelsolin repeat Arf PF00025.16 EGD97346.1 - 2.9e-60 202.4 0.3 3.3e-60 202.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGD97346.1 - 1.9e-08 33.4 1.7 3.4e-06 25.9 0.2 2.7 2 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.17 EGD97346.1 - 3.7e-08 32.9 0.0 4.6e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGD97346.1 - 2.6e-07 30.0 0.0 3.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGD97346.1 - 2.2e-06 27.5 0.0 3.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD97346.1 - 1.8e-05 25.1 0.0 2.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EGD97346.1 - 4.3e-05 23.0 0.0 0.0012 18.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGD97346.1 - 0.0035 16.5 0.0 0.0048 16.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit HCV_NS1 PF01560.12 EGD97346.1 - 0.0048 15.4 0.0 0.0057 15.1 0.0 1.1 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein E2/NS1 Acetyltransf_4 PF13420.1 EGD97347.1 - 0.028 14.3 0.1 0.07 13.0 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DEAD PF00270.24 EGD97348.1 - 1.7e-43 148.0 0.1 4.4e-43 146.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD97348.1 - 5.4e-25 87.0 0.0 2.3e-24 85.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EGD97348.1 - 0.00015 20.3 1.0 0.00093 17.7 0.1 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF1253) HMGL-like PF00682.14 EGD97349.1 - 4.3e-67 226.2 0.0 6.9e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EGD97349.1 - 9.3e-21 74.0 0.0 1.8e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain AMP-binding PF00501.23 EGD97350.1 - 3.2e-57 193.7 0.9 1.9e-23 82.5 0.0 4.9 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 EGD97350.1 - 8.5e-09 36.0 0.0 2.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 EGD97350.1 - 0.0017 18.1 0.1 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Gas vesicle protein G Carb_anhydrase PF00194.16 EGD97351.1 - 4.4e-23 81.5 0.1 1.7e-22 79.6 0.1 1.8 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase RNR_inhib PF08591.5 EGD97352.1 - 7.5e-09 36.3 0.9 7.5e-09 36.3 0.6 1.6 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor SDA1 PF05285.7 EGD97353.1 - 6.2e-76 255.7 32.5 6.2e-76 255.7 22.5 2.2 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 EGD97353.1 - 7.4e-23 80.5 0.1 2.1e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 NUC130/3NT domain Ribosomal_S7 PF00177.16 EGD97354.1 - 8.4e-41 138.9 1.2 1e-40 138.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Methyltransf_23 PF13489.1 EGD97355.1 - 4e-15 55.8 0.0 7.3e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD97355.1 - 2.1e-06 27.4 0.0 9.9e-06 25.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD97355.1 - 4.9e-06 26.9 0.0 1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD97355.1 - 1.1e-05 25.7 0.0 7.6e-05 23.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD97355.1 - 2.5e-05 24.8 0.0 0.0003 21.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD97355.1 - 4.9e-05 23.6 0.0 0.00013 22.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGD97355.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 EGD97355.1 - 0.019 15.0 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EGD97355.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGD97355.1 - 0.18 11.1 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.17 EGD97356.1 - 3.7e-65 220.2 0.0 4.4e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EGD97357.1 - 1.5e-17 63.6 0.0 9.1e-17 61.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97357.1 - 4.9e-06 25.8 0.1 0.046 12.7 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Metallophos PF00149.23 EGD97358.1 - 1.1e-08 34.7 2.4 2e-08 33.8 1.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EGD97358.1 - 0.0028 17.6 0.0 0.011 15.7 0.0 1.9 1 1 0 2 2 2 1 5'-nucleotidase, C-terminal domain DmpG_comm PF07836.6 EGD97358.1 - 0.095 12.1 0.0 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 DmpG-like communication domain Pkinase PF00069.20 EGD97359.1 - 6.7e-23 81.1 0.0 1.1e-22 80.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97359.1 - 0.00092 18.3 0.4 0.011 14.8 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGD97359.1 - 0.064 12.9 0.7 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family 4HBT_3 PF13622.1 EGD97360.1 - 5.2e-44 150.9 1.0 6.6e-44 150.5 0.7 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EGD97360.1 - 5.9e-25 87.4 0.0 1.3e-11 44.2 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase DUF3445 PF11927.3 EGD97361.1 - 3.4e-60 203.5 0.0 4.8e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Lipase_GDSL_3 PF14606.1 EGD97361.1 - 0.063 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family HSP70 PF00012.15 EGD97364.1 - 1.1e-10 40.0 0.1 3.5e-09 35.1 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EGD97364.1 - 0.0048 16.5 0.2 0.0098 15.5 0.1 1.4 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EGD97364.1 - 0.091 11.3 0.0 0.27 9.7 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein N2227 PF07942.7 EGD97365.1 - 3.2e-87 291.9 0.0 5.4e-87 291.1 0.0 1.4 1 1 0 1 1 1 1 N2227-like protein HsdM_N PF12161.3 EGD97365.1 - 0.16 12.3 0.3 0.35 11.2 0.2 1.6 1 0 0 1 1 1 0 HsdM N-terminal domain Fungal_trans PF04082.13 EGD97368.1 - 1.5e-23 83.0 0.3 2.4e-23 82.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD97368.1 - 1.8e-05 24.5 12.8 1.8e-05 24.5 8.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin_2 PF01920.15 EGD97369.1 - 1.7e-10 40.5 4.1 4.4e-08 32.8 0.2 2.1 2 0 0 2 2 2 2 Prefoldin subunit Osmo_CC PF08946.5 EGD97369.1 - 0.033 14.2 1.5 0.072 13.1 1.1 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Vps52 PF04129.7 EGD97369.1 - 0.039 12.4 0.3 0.085 11.3 0.1 1.5 1 1 1 2 2 2 0 Vps52 / Sac2 family TBCA PF02970.11 EGD97369.1 - 0.041 13.9 3.6 0.064 13.3 0.2 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A TBPIP PF07106.8 EGD97369.1 - 0.055 13.0 1.8 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ORF6C PF10552.4 EGD97369.1 - 0.13 11.9 0.9 1.3 8.7 0.1 2.0 2 0 0 2 2 2 0 ORF6C domain KfrA_N PF11740.3 EGD97369.1 - 0.17 12.3 4.7 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term CENP-F_leu_zip PF10473.4 EGD97369.1 - 0.22 11.3 8.6 0.14 12.0 0.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 EGD97369.1 - 0.81 9.7 5.6 0.52 10.3 0.4 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Rho_Binding PF08912.6 EGD97369.1 - 2.9 8.2 8.6 0.35 11.1 0.8 2.1 2 0 0 2 2 2 0 Rho Binding DUF3847 PF12958.2 EGD97369.1 - 7.2 6.4 8.7 7.9 6.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) bZIP_1 PF00170.16 EGD97369.1 - 8.9 6.3 9.7 0.34 10.9 1.8 2.0 2 0 0 2 2 2 0 bZIP transcription factor ATG27 PF09451.5 EGD97370.1 - 2.8e-59 200.5 6.3 6.7e-59 199.3 4.4 1.8 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EGD97370.1 - 0.0037 17.0 0.1 0.79 9.4 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF1669 PF07894.7 EGD97370.1 - 0.11 11.6 0.2 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) Vfa1 PF08432.5 EGD97370.1 - 0.32 11.0 5.4 0.45 10.5 3.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1242 PF06842.7 EGD97370.1 - 1.1 8.8 5.1 0.39 10.2 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) KAAG1 PF15354.1 EGD97371.1 - 0.13 12.5 4.7 0.08 13.2 1.3 2.1 2 1 1 3 3 3 0 Kidney-associated antigen 1 AAA_2 PF07724.9 EGD97374.1 - 2.4e-44 151.2 0.0 1.6e-42 145.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGD97374.1 - 1.1e-26 93.5 0.0 8.2e-15 55.1 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EGD97374.1 - 3.9e-22 77.9 0.1 1.5e-21 76.0 0.0 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EGD97374.1 - 5.1e-16 59.2 4.6 2.4e-06 27.6 0.0 5.4 3 2 2 5 5 5 2 AAA ATPase domain AAA_5 PF07728.9 EGD97374.1 - 5.4e-15 55.3 1.1 3.7e-08 33.1 0.0 3.9 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGD97374.1 - 1.4e-13 51.1 0.4 5.8e-05 23.2 0.0 3.7 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EGD97374.1 - 4.2e-09 36.1 0.0 4.7e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 EGD97374.1 - 2.5e-08 34.7 1.7 0.0056 17.5 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EGD97374.1 - 6.7e-08 32.8 0.0 0.0062 16.8 0.0 3.7 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EGD97374.1 - 1.9e-07 30.6 0.0 0.022 14.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EGD97374.1 - 2.1e-07 30.6 0.0 0.013 15.2 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Clp_N PF02861.15 EGD97374.1 - 2.8e-07 30.3 4.1 0.0076 16.1 0.0 4.3 4 1 0 4 4 2 2 Clp amino terminal domain Arch_ATPase PF01637.13 EGD97374.1 - 5.3e-06 26.2 5.9 0.026 14.1 0.0 5.1 7 0 0 7 7 5 2 Archaeal ATPase AAA_28 PF13521.1 EGD97374.1 - 1.4e-05 25.1 0.6 0.5 10.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 EGD97374.1 - 1.7e-05 24.5 0.0 0.091 12.4 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGD97374.1 - 1.8e-05 24.6 0.0 0.18 11.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGD97374.1 - 3.2e-05 24.0 0.0 0.45 10.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 EGD97374.1 - 3.7e-05 23.0 0.0 0.11 11.6 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGD97374.1 - 8.1e-05 22.2 0.0 0.83 9.2 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EGD97374.1 - 0.00011 21.3 0.2 0.2 10.7 0.0 3.6 4 0 0 4 4 3 1 Zeta toxin MMR_HSR1 PF01926.18 EGD97374.1 - 0.00011 22.0 0.0 0.0015 18.5 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EGD97374.1 - 0.00024 20.5 0.0 0.78 9.1 0.0 3.3 2 1 1 3 3 3 2 AAA domain ABC_tran PF00005.22 EGD97374.1 - 0.00035 20.8 0.2 0.98 9.7 0.0 3.3 3 0 0 3 3 2 1 ABC transporter T2SE PF00437.15 EGD97374.1 - 0.0007 18.5 0.0 0.028 13.3 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein NTPase_1 PF03266.10 EGD97374.1 - 0.00078 19.1 0.1 0.095 12.4 0.0 3.4 3 0 0 3 3 3 1 NTPase AAA_10 PF12846.2 EGD97374.1 - 0.00083 18.8 0.7 0.25 10.7 0.0 3.8 3 2 1 4 4 4 1 AAA-like domain DUF258 PF03193.11 EGD97374.1 - 0.0011 18.2 0.0 0.43 9.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Torsin PF06309.6 EGD97374.1 - 0.0013 18.6 0.0 0.0048 16.7 0.0 1.9 2 0 0 2 2 2 1 Torsin AAA_29 PF13555.1 EGD97374.1 - 0.0016 17.9 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ResIII PF04851.10 EGD97374.1 - 0.0018 18.0 0.0 0.37 10.5 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EGD97374.1 - 0.0022 17.6 0.0 2.2 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EGD97374.1 - 0.0033 17.0 0.0 0.24 11.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.17 EGD97374.1 - 0.0067 15.8 0.0 1.2 8.5 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EGD97374.1 - 0.0092 15.5 0.1 7 6.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.1 EGD97374.1 - 0.031 14.2 0.0 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EGD97374.1 - 0.042 13.4 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 EGD97374.1 - 0.1 12.1 0.1 17 4.8 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 EGD97374.1 - 1.3 9.3 0.0 1.3 9.3 0.0 4.5 4 1 0 4 4 3 0 AAA domain SNF2_N PF00176.18 EGD97375.1 - 1.1e-69 234.5 0.0 1.4e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD97375.1 - 3.3e-12 46.0 0.0 6.8e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD97375.1 - 4.5e-05 23.3 0.0 0.00018 21.4 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1510 PF07423.6 EGD97376.1 - 0.00017 21.0 4.4 0.00019 20.8 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 EGD97376.1 - 0.0013 18.2 0.3 0.0018 17.7 0.2 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF1183 PF06682.7 EGD97376.1 - 0.02 14.5 0.0 0.022 14.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF2919 PF11143.3 EGD97376.1 - 0.068 13.0 0.0 0.081 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) Trypan_PARP PF05887.6 EGD97376.1 - 1.3 8.8 8.4 1.5 8.6 5.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NOA36 PF06524.7 EGD97376.1 - 3 7.0 20.5 3.6 6.7 14.2 1.1 1 0 0 1 1 1 0 NOA36 protein Spore_YtfJ PF09579.5 EGD97376.1 - 3.2 7.6 6.3 0.17 11.7 0.8 1.6 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) EBP PF05241.7 EGD97377.1 - 2.8e-65 218.9 12.8 3.4e-65 218.7 8.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2347 PF09804.4 EGD97378.1 - 7.2e-102 340.4 0.0 1.4e-101 339.5 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EGD97378.1 - 6e-50 169.7 3.3 9.4e-50 169.1 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 EGD97378.1 - 3.2e-07 29.1 0.0 0.0017 16.8 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 EGD97378.1 - 0.00044 19.9 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Barttin PF15462.1 EGD97378.1 - 0.021 14.4 0.9 0.047 13.3 0.7 1.5 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Spc7 PF08317.6 EGD97379.1 - 0.52 8.9 13.8 1 7.9 9.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Bacillus_HBL PF05791.6 EGD97379.1 - 1.1 8.6 7.7 0.15 11.4 2.4 1.6 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF342 PF03961.8 EGD97379.1 - 3.4 5.9 8.4 5.8 5.2 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Tubulin_3 PF14881.1 EGD97380.1 - 2.5e-82 274.6 0.1 4.1e-82 274.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EGD97380.1 - 4.1e-23 81.6 0.0 1.2e-22 80.1 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EGD97380.1 - 0.0034 17.2 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain HSP70 PF00012.15 EGD97383.1 - 1.2e-62 211.6 17.8 8.7e-62 208.8 1.9 2.8 3 0 0 3 3 3 2 Hsp70 protein FGGY_C PF02782.11 EGD97383.1 - 0.045 13.3 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain MFS_1 PF07690.11 EGD97384.1 - 2.4e-31 108.7 57.3 7.9e-30 103.7 38.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD97384.1 - 1.4e-08 33.8 14.8 1.4e-08 33.8 10.3 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter tRNA-synt_1c PF00749.16 EGD97386.1 - 6.4e-94 314.1 0.0 8.6e-94 313.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGD97386.1 - 2.1e-29 102.4 0.0 5.8e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain ATP-grasp_4 PF13535.1 EGD97389.1 - 3.1e-05 23.8 0.0 6.8e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGD97389.1 - 0.0003 20.2 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus PHTB1_C PF14728.1 EGD97390.1 - 0.065 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus GDPD PF03009.12 EGD97391.1 - 1.1e-23 84.1 0.0 3.3e-23 82.5 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EGD97391.1 - 7.4e-16 58.2 0.3 2.5e-06 27.7 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGD97391.1 - 9.6e-12 44.1 0.1 1.6e-06 27.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EGD97391.1 - 1.7e-11 44.3 0.7 1.5e-05 25.3 0.0 4.9 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD97391.1 - 1.2e-07 31.7 0.3 0.0018 18.4 0.1 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD97391.1 - 4.1e-06 26.5 0.0 0.022 14.9 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat SPX PF03105.14 EGD97391.1 - 0.0012 18.7 2.3 0.06 13.1 0.0 2.6 3 0 0 3 3 3 1 SPX domain DUF1509 PF07420.6 EGD97391.1 - 0.29 10.3 2.2 0.46 9.6 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Fe-S_assembly PF04384.8 EGD97392.1 - 0.011 16.1 0.0 0.014 15.7 0.0 1.1 1 0 0 1 1 1 0 Iron-sulphur cluster assembly Fungal_trans PF04082.13 EGD97394.1 - 7e-23 80.8 0.3 4.1e-21 75.0 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD97394.1 - 1.8e-07 30.9 8.0 2.9e-07 30.2 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain But2 PF09792.4 EGD97396.1 - 0.027 14.2 0.0 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin 3 binding protein But2 C-terminal domain MFS_1 PF07690.11 EGD97397.1 - 4.5e-45 153.8 35.4 4.5e-45 153.8 24.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD97397.1 - 2e-13 49.7 15.3 3.9e-13 48.8 10.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EGD97397.1 - 4.1e-05 21.9 1.1 4.1e-05 21.9 0.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF697 PF05128.7 EGD97397.1 - 2.6 7.5 4.6 7.9 5.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF697) Alpha-amylase PF00128.19 EGD97399.1 - 6.3e-31 107.9 0.1 2e-30 106.2 0.1 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EGD97399.1 - 2.9e-06 25.3 0.6 0.0028 15.5 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 3A PF00803.13 EGD97399.1 - 0.061 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family DEAD PF00270.24 EGD97400.1 - 1e-25 90.1 0.2 1.7e-24 86.1 0.1 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD97400.1 - 3.8e-21 74.7 0.1 8.6e-21 73.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD97400.1 - 0.00013 21.8 0.6 0.00041 20.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EGD97400.1 - 0.016 13.6 0.0 0.94 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Enkurin PF13864.1 EGD97400.1 - 5.2 7.3 9.3 1.9 8.7 3.2 2.5 2 0 0 2 2 2 0 Calmodulin-binding Ribonuc_L-PSP PF01042.16 EGD97401.1 - 1.1e-37 128.5 0.0 1.2e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GFA PF04828.9 EGD97403.1 - 0.0025 17.7 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme HLH PF00010.21 EGD97404.1 - 1e-08 34.6 0.1 4e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Spc7 PF08317.6 EGD97404.1 - 0.097 11.3 0.4 0.11 11.1 0.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein HNH_2 PF13391.1 EGD97405.1 - 9.3e-13 47.7 0.0 1.8e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Maf PF02545.9 EGD97406.1 - 1.4e-41 141.7 0.0 1.8e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein CybS PF05328.7 EGD97407.1 - 5.6e-50 168.3 0.0 6.8e-50 168.1 0.0 1.1 1 0 0 1 1 1 1 CybS Glyco_trans_1_4 PF13692.1 EGD97407.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 ADH_zinc_N PF00107.21 EGD97408.1 - 1.9e-21 75.9 0.0 3e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGD97408.1 - 7.1e-10 39.8 0.0 1.2e-09 39.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_M16 PF00675.15 EGD97410.1 - 9.6e-56 187.6 0.1 3.3e-55 185.9 0.1 1.9 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGD97410.1 - 5.2e-41 140.3 0.0 5.4e-40 137.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain MFS_1 PF07690.11 EGD97411.1 - 1e-32 113.2 61.3 1.5e-31 109.3 32.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Nitroreductase PF00881.19 EGD97412.1 - 6.8e-16 58.5 0.0 8.2e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Epimerase PF01370.16 EGD97413.1 - 9.4e-21 74.3 0.0 1.2e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD97413.1 - 3.4e-09 35.8 0.0 4.3e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGD97413.1 - 5.6e-07 29.7 0.0 8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGD97413.1 - 1.5e-05 25.0 0.0 3.2e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EGD97413.1 - 3e-05 23.0 0.1 0.1 11.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EGD97413.1 - 0.00089 18.2 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EGD97413.1 - 0.0024 17.5 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EGD97413.1 - 0.093 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Fibrillarin PF01269.12 EGD97414.1 - 1.1e-107 358.1 0.0 1.3e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EGD97414.1 - 1.2e-05 24.9 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EGD97414.1 - 0.038 13.5 0.1 0.061 12.8 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EGD97414.1 - 0.054 13.0 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3455 PF11937.3 EGD97415.1 - 9.3e-41 139.7 0.0 1.1e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) CASP_C PF08172.7 EGD97416.1 - 1.2e-87 293.0 1.0 1.2e-87 293.0 0.7 3.7 3 1 0 3 3 3 1 CASP C terminal Vps39_2 PF10367.4 EGD97417.1 - 2.5e-08 34.0 0.0 7.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EGD97417.1 - 0.1 11.9 0.0 13 5.0 0.0 2.4 2 0 0 2 2 2 0 CNH domain PALP PF00291.20 EGD97418.1 - 2.6e-48 164.8 1.3 2.9e-48 164.6 0.1 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 EGD97418.1 - 1.7e-24 86.3 0.0 3.6e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGD97418.1 - 1.3e-18 66.7 0.0 3.8e-18 65.2 0.0 1.9 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 EGD97418.1 - 0.0015 17.3 0.0 2.4 6.8 0.0 3.1 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.12 EGD97418.1 - 0.0085 15.8 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M28 UBA_4 PF14555.1 EGD97419.1 - 2e-11 43.2 0.0 3.7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EGD97419.1 - 2.6e-09 37.0 0.0 6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain DDHD PF02862.12 EGD97419.1 - 0.042 13.6 1.1 0.073 12.8 0.7 1.5 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 EGD97419.1 - 0.15 9.7 3.6 0.2 9.3 2.5 1.1 1 0 0 1 1 1 0 Ycf1 AAR2 PF05282.6 EGD97419.1 - 0.2 10.5 4.7 0.3 9.9 3.3 1.2 1 0 0 1 1 1 0 AAR2 protein Pkinase PF00069.20 EGD97420.1 - 1.9e-05 23.9 0.0 3.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LSM PF01423.17 EGD97421.1 - 2.2e-18 65.5 0.7 3e-18 65.1 0.5 1.2 1 0 0 1 1 1 1 LSM domain FimP PF09766.4 EGD97421.1 - 0.039 13.0 0.3 0.045 12.8 0.2 1.0 1 0 0 1 1 1 0 Fms-interacting protein SM-ATX PF14438.1 EGD97421.1 - 0.05 13.5 0.2 0.093 12.6 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF2201_N PF13203.1 EGD97421.1 - 1.1 8.4 4.4 1.2 8.2 3.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4175 PF13779.1 EGD97421.1 - 1.9 6.1 12.2 1.9 6.0 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Zn_clus PF00172.13 EGD97422.1 - 0.53 10.2 11.9 1.5 8.8 8.2 1.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FKBP_N PF01346.13 EGD97422.1 - 0.76 9.8 6.8 1.6 8.7 2.3 2.5 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Dioxygenase_C PF00775.16 EGD97423.1 - 3.4e-54 182.8 0.0 5e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EGD97423.1 - 7.8e-18 64.2 0.0 1.8e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EGD97423.1 - 0.034 14.2 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Ribosomal_L22 PF00237.14 EGD97424.1 - 2.9e-34 117.1 0.0 3.9e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e 2-Hacid_dh_C PF02826.14 EGD97425.1 - 6.3e-56 188.3 0.0 8.5e-56 187.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD97425.1 - 7.1e-18 64.3 0.0 7.9e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGD97425.1 - 0.001 18.9 0.2 0.0021 17.9 0.1 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EGD97425.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_N PF08240.7 EGD97426.1 - 1.9e-26 91.9 0.1 3.1e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD97426.1 - 3.6e-10 39.5 0.0 1.2e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.11 EGD97426.1 - 0.041 13.3 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EGD97426.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ldh_1_N PF00056.18 EGD97426.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 EGD97426.1 - 0.091 12.5 0.2 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 ThiF family Saccharop_dh PF03435.13 EGD97426.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase adh_short PF00106.20 EGD97427.1 - 1.1e-27 97.0 0.3 1.3e-27 96.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD97427.1 - 1.7e-15 57.4 0.1 2e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD97427.1 - 2.5e-11 43.5 0.2 3.7e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGD97427.1 - 7.3e-05 22.8 0.5 0.0034 17.4 0.4 2.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGD97427.1 - 0.00014 21.4 0.2 0.00027 20.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGD97427.1 - 0.005 16.5 0.1 0.015 15.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EGD97427.1 - 0.0087 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Fungal_trans PF04082.13 EGD97428.1 - 3.8e-11 42.3 1.1 8.1e-11 41.2 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD97428.1 - 5.8e-06 26.1 11.1 1e-05 25.3 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3939 PF13075.1 EGD97428.1 - 0.2 11.3 0.2 21 4.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3939) RP-C_C PF11800.3 EGD97428.1 - 6.1 6.4 6.4 14 5.2 4.4 1.6 1 1 0 1 1 1 0 Replication protein C C-terminal region DUF4614 PF15391.1 EGD97428.1 - 6.4 6.5 11.0 22 4.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) adh_short_C2 PF13561.1 EGD97430.1 - 1.8e-11 44.3 0.0 2e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_transf_5 PF08323.6 EGD97430.1 - 0.0037 16.7 0.0 0.0037 16.7 0.0 1.1 1 0 0 1 1 1 1 Starch synthase catalytic domain Gag_spuma PF03276.9 EGD97430.1 - 0.03 12.6 0.0 0.036 12.4 0.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein adh_short PF00106.20 EGD97430.1 - 0.1 12.4 0.2 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Ferric_reduct PF01794.14 EGD97431.1 - 5.3e-24 84.7 6.4 5.3e-24 84.7 4.5 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EGD97431.1 - 3.3e-16 59.5 0.1 1e-13 51.4 0.0 2.7 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGD97431.1 - 1.2e-12 47.5 0.0 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EGD97431.1 - 0.048 14.2 0.0 0.68 10.5 0.0 2.6 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF2374 PF09574.5 EGD97431.1 - 1.7 8.3 6.4 0.48 10.0 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) GAT PF03127.9 EGD97432.1 - 7.6e-15 54.7 0.2 2.7e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 EGD97432.1 - 0.032 13.8 0.3 0.18 11.4 0.0 2.3 3 0 0 3 3 3 0 VHS domain Pyr_redox_2 PF07992.9 EGD97433.1 - 1.3e-22 80.6 0.0 1.9e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD97433.1 - 2.7e-09 37.3 0.0 1.1e-08 35.3 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD97433.1 - 0.019 15.0 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD97433.1 - 0.06 13.1 0.5 0.69 9.6 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Fungal_trans_2 PF11951.3 EGD97437.1 - 8.8e-09 34.4 0.1 4.7e-06 25.4 0.2 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD97437.1 - 2.5e-07 30.4 10.0 5.3e-07 29.4 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Staphylcoagulse PF04022.7 EGD97438.1 - 6 6.3 6.4 5.5 6.4 0.4 2.6 2 1 1 3 3 3 0 Staphylocoagulase repeat Pectate_lyase_3 PF12708.2 EGD97440.1 - 1.9e-89 299.6 20.5 5.9e-70 235.8 6.5 3.1 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EGD97440.1 - 1.6e-06 27.4 4.0 0.00088 18.6 0.1 3.0 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Aminotran_1_2 PF00155.16 EGD97442.1 - 3.1e-09 36.2 0.0 0.00063 18.8 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class I and II MIP-T3 PF10243.4 EGD97443.1 - 0.77 8.1 2.9 0.99 7.7 2.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ribosomal_L10 PF00466.15 EGD97444.1 - 5.3e-16 58.3 0.0 1.3e-15 57.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 TIM PF00121.13 EGD97445.1 - 1.4e-89 299.3 0.6 1.6e-89 299.1 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF3860 PF12976.2 EGD97445.1 - 0.035 13.8 1.1 0.06 13.1 0.2 1.8 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) DUF3722 PF12519.3 EGD97446.1 - 8.8e-87 290.6 1.3 1.1e-86 290.2 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) YjeF_N PF03853.10 EGD97447.1 - 4.4e-33 114.2 0.1 6.6e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EGD97447.1 - 6.5e-09 36.2 0.9 6.5e-09 36.2 0.6 2.4 3 0 0 3 3 3 1 FDF domain Ribosomal_S5_C PF03719.10 EGD97447.1 - 0.084 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Pkinase PF00069.20 EGD97448.1 - 1.5e-18 66.9 0.2 3.2e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97448.1 - 4.9e-10 38.9 0.0 2.1e-07 30.2 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.17 EGD97448.1 - 2.9e-06 26.7 0.1 5e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pro_isomerase PF00160.16 EGD97449.1 - 1.3e-36 126.1 0.0 2.2e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EGD97449.1 - 7.9e-06 25.2 1.3 1.8e-05 24.0 0.1 2.0 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 EGD97449.1 - 0.00054 19.8 0.0 0.0023 17.8 0.0 2.0 1 1 0 1 1 1 1 U-box domain DFF40 PF09230.5 EGD97449.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa GMAP PF06540.6 EGD97450.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Galanin message associated peptide (GMAP) DUF2204 PF09970.4 EGD97450.1 - 0.1 12.0 0.2 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) PIF1 PF05970.9 EGD97453.1 - 2e-52 178.3 0.1 2e-47 161.8 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EGD97453.1 - 5.3e-18 65.3 0.0 1e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGD97453.1 - 5.1e-08 33.1 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 EGD97453.1 - 7.7e-05 20.6 0.1 0.00046 18.0 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA PF00004.24 EGD97453.1 - 0.00021 21.4 0.3 0.00068 19.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGD97453.1 - 0.00035 20.2 1.3 0.00084 19.0 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 EGD97453.1 - 0.00042 20.4 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_14 PF13173.1 EGD97453.1 - 0.0015 18.4 0.1 0.0071 16.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EGD97453.1 - 0.0018 17.8 0.1 0.46 9.9 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EGD97453.1 - 0.0024 17.9 0.4 0.058 13.3 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EGD97453.1 - 0.0053 16.4 0.1 0.018 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 EGD97453.1 - 0.0084 15.3 0.0 0.031 13.5 0.0 1.9 1 0 0 1 1 1 1 PhoH-like protein T2SE PF00437.15 EGD97453.1 - 0.022 13.6 0.0 0.045 12.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 EGD97453.1 - 0.033 13.1 1.9 0.042 12.8 0.0 2.3 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EGD97453.1 - 0.049 13.8 0.1 0.26 11.4 0.0 2.4 2 1 0 2 2 1 0 RNA helicase Arch_ATPase PF01637.13 EGD97453.1 - 0.1 12.2 0.6 0.45 10.1 0.4 2.0 1 1 0 1 1 1 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 EGD97453.1 - 0.11 11.0 1.5 0.15 10.6 0.1 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.2 EGD97453.1 - 0.17 10.9 0.0 0.36 9.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 PTCB-BRCT PF12738.2 EGD97454.1 - 1.7e-43 146.3 0.7 3.5e-20 71.6 0.1 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 EGD97454.1 - 5.6e-28 96.9 0.1 2.2e-11 43.7 0.1 4.0 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain Dynamin_N PF00350.18 EGD97455.1 - 1.4e-16 60.7 3.7 1.7e-16 60.4 0.1 2.9 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EGD97455.1 - 2.6e-10 40.2 0.1 1.7e-08 34.3 0.0 3.5 2 2 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD97455.1 - 2.5e-07 30.3 0.8 3e-06 26.7 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGD97455.1 - 0.01 16.3 0.1 0.66 10.4 0.1 2.9 1 1 0 1 1 1 0 Miro-like protein Glypican PF01153.14 EGD97455.1 - 0.034 12.7 0.0 0.063 11.8 0.0 1.4 1 0 0 1 1 1 0 Glypican AAA_29 PF13555.1 EGD97455.1 - 0.037 13.5 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EGD97455.1 - 0.049 13.9 0.2 0.39 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EGD97455.1 - 0.067 12.4 0.3 35 3.6 0.0 3.9 5 0 0 5 5 5 0 Ferrous iron transport protein B Snf7 PF03357.16 EGD97456.1 - 7.8e-36 123.0 17.5 2.8e-35 121.2 10.8 2.0 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 EGD97456.1 - 0.082 10.7 4.4 0.096 10.5 3.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ist1 PF03398.9 EGD97456.1 - 0.09 12.1 6.7 0.14 11.5 4.6 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway TPR_MLP1_2 PF07926.7 EGD97456.1 - 1.3 8.8 10.3 2.5 7.8 7.1 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PP2C PF00481.16 EGD97457.1 - 1.1e-63 215.0 1.3 1.6e-50 171.8 0.0 3.8 2 1 2 4 4 4 3 Protein phosphatase 2C Mhr1 PF12829.2 EGD97458.1 - 4.1e-30 103.4 0.2 1.1e-29 102.1 0.1 1.7 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination MRP-S26 PF14943.1 EGD97458.1 - 0.54 9.7 15.0 0.95 9.0 10.4 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Atg14 PF10186.4 EGD97459.1 - 2.1e-20 72.8 0.0 3.9e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 MRFAP1 PF15155.1 EGD97459.1 - 0.32 11.3 3.0 0.56 10.5 2.0 1.4 1 0 0 1 1 1 0 MORF4 family-associated protein1 Zn_clus PF00172.13 EGD97460.1 - 4.5e-07 29.6 14.8 7.7e-07 28.9 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EGD97461.1 - 3.2e-05 23.5 0.2 7.7e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like PalH PF08733.5 EGD97462.1 - 1.1e-99 333.6 0.1 6.5e-99 331.0 0.1 1.9 1 1 0 1 1 1 1 PalH/RIM21 TIP120 PF08623.5 EGD97464.1 - 1.3e-64 216.8 0.1 8.4e-62 207.7 0.0 3.7 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 EGD97464.1 - 4.5e-15 54.3 3.0 0.079 13.0 0.0 8.9 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 EGD97464.1 - 1.9e-14 53.7 9.4 0.055 13.7 0.0 7.6 6 1 0 6 6 6 4 HEAT repeats Adaptin_N PF01602.15 EGD97464.1 - 4.7e-06 25.2 0.4 1.2 7.3 0.1 5.3 4 2 1 5 5 5 2 Adaptin N terminal region Cnd1 PF12717.2 EGD97464.1 - 0.00036 20.4 0.1 0.0061 16.4 0.0 3.3 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EGD97464.1 - 0.00052 19.8 1.3 0.028 14.3 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 EGD97464.1 - 0.00077 19.8 0.0 5.6 7.4 0.0 5.8 6 2 0 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGD97464.1 - 0.027 14.9 20.3 10 6.7 0.0 10.9 11 2 3 14 14 13 0 HEAT-like repeat DRIM PF07539.7 EGD97464.1 - 0.041 13.2 0.2 2.4 7.5 0.0 3.3 3 0 0 3 3 3 0 Down-regulated in metastasis DUF3295 PF11702.3 EGD97464.1 - 0.046 12.7 0.1 0.074 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) HEAT_PBS PF03130.11 EGD97464.1 - 7.9 7.2 10.0 0.72 10.4 0.2 4.7 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Mitofilin PF09731.4 EGD97465.1 - 0.031 12.9 16.2 0.032 12.9 11.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GAGA_bind PF06217.7 EGD97465.1 - 6.6 6.5 11.7 9.1 6.1 8.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 EGD97465.1 - 8 5.7 21.5 10 5.4 14.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TRAM_LAG1_CLN8 PF03798.11 EGD97466.1 - 3.3e-36 124.6 17.9 5.9e-36 123.8 12.4 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EGD97466.1 - 8.9e-22 76.3 0.1 2.2e-21 75.1 0.0 1.8 2 0 0 2 2 2 1 TRAM1-like protein Sugar_tr PF00083.19 EGD97467.1 - 3.9e-104 348.7 17.4 4.7e-104 348.4 12.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD97467.1 - 2.2e-26 92.4 32.7 1e-25 90.2 15.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGD97467.1 - 7.2e-07 27.9 0.3 7.2e-07 27.9 0.2 3.6 4 0 0 4 4 4 2 MFS/sugar transport protein DUF791 PF05631.9 EGD97467.1 - 3.1e-06 26.1 0.9 6.2e-06 25.1 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) CLIP PF12032.3 EGD97468.1 - 0.014 15.4 0.2 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Regulatory CLIP domain of proteinases Transglut_core PF01841.14 EGD97469.1 - 4.8e-14 52.5 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily EDR1 PF14381.1 EGD97469.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Ras PF00071.17 EGD97470.1 - 5.5e-31 107.1 0.2 8e-31 106.6 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD97470.1 - 2.7e-20 73.0 0.1 1.2e-19 70.8 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGD97470.1 - 1.8e-06 27.3 0.1 3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGD97470.1 - 9.2e-05 21.6 0.2 9.2e-05 21.6 0.1 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region BaxI_1 PF12811.2 EGD97470.1 - 0.054 12.6 0.3 0.085 12.0 0.2 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like G-alpha PF00503.15 EGD97470.1 - 0.22 10.1 10.1 0.3 9.7 0.0 2.5 1 1 0 2 2 2 0 G-protein alpha subunit BAF1_ABF1 PF04684.8 EGD97470.1 - 7.7 5.2 11.8 12 4.5 8.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor WD40 PF00400.27 EGD97471.1 - 7.2e-27 92.2 6.5 7.4e-10 38.3 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGD97471.1 - 3.9e-19 68.3 0.0 7.8e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 EGD97471.1 - 0.00072 17.8 1.2 0.0017 16.6 0.1 1.8 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Vpu PF00558.14 EGD97471.1 - 0.27 10.8 1.7 0.53 9.8 1.2 1.4 1 0 0 1 1 1 0 Vpu protein PYST-C1 PF09690.5 EGD97472.1 - 0.062 12.9 1.7 0.14 11.8 1.2 1.5 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) Fungal_trans PF04082.13 EGD97475.1 - 6.5e-22 77.6 0.8 1.3e-21 76.6 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EGD97475.1 - 1.2e-09 37.9 13.9 4.6e-05 23.5 1.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD97475.1 - 5.6e-06 26.3 6.9 5.6e-06 26.3 4.8 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGD97475.1 - 0.0011 19.1 14.6 0.11 12.9 1.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger AAA PF00004.24 EGD97477.1 - 3.9e-08 33.5 2.9 2e-07 31.2 0.5 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EGD97477.1 - 1.5e-05 23.9 0.2 0.0011 17.7 0.1 3.1 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EGD97477.1 - 0.002 18.9 0.0 0.0052 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGD97477.1 - 0.0036 17.4 0.1 0.02 15.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD97477.1 - 0.0055 16.7 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EGD97477.1 - 0.037 13.7 0.0 0.091 12.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 EGD97477.1 - 0.17 10.5 0.1 0.27 9.8 0.1 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Tmemb_cc2 PF10267.4 EGD97479.1 - 0.01 14.4 2.4 0.013 14.1 1.7 1.3 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein GNT-I PF03071.10 EGD97479.1 - 0.051 12.1 0.8 0.062 11.8 0.5 1.1 1 0 0 1 1 1 0 GNT-I family Prefoldin_3 PF13758.1 EGD97479.1 - 0.054 13.2 1.6 0.14 11.9 0.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit RHH_2 PF03693.9 EGD97479.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0156) Nha1_C PF08619.5 EGD97480.1 - 7.2e-70 236.4 11.8 1.3e-69 235.6 8.2 1.3 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EGD97480.1 - 5.3e-64 216.1 19.0 6.3e-64 215.8 13.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EGD97480.1 - 0.093 12.6 2.9 0.17 11.8 0.2 2.6 2 0 0 2 2 2 0 YrhC-like protein DUF21 PF01595.15 EGD97480.1 - 3.7 6.8 8.6 0.38 10.0 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF21 SAM_2 PF07647.12 EGD97481.1 - 3.8e-15 55.4 0.0 6.3e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EGD97481.1 - 6.3e-15 55.4 0.0 1.4e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 EGD97481.1 - 3.1e-11 43.2 0.0 4.7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EnY2 PF10163.4 EGD97482.1 - 0.0026 17.6 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 Transcription factor e(y)2 AAA PF00004.24 EGD97483.1 - 5.6e-97 321.0 0.0 1.1e-47 161.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EGD97483.1 - 7.8e-20 70.6 1.0 2.1e-19 69.2 0.4 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EGD97483.1 - 2.5e-14 53.5 0.0 9.1e-08 32.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EGD97483.1 - 4.2e-13 48.8 0.0 1.7e-05 24.0 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EGD97483.1 - 6.8e-13 48.7 0.0 8.8e-06 25.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EGD97483.1 - 3.6e-11 43.9 0.0 0.00069 20.4 0.0 3.3 2 1 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EGD97483.1 - 3.7e-11 43.2 0.3 0.0035 17.4 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGD97483.1 - 5.8e-11 42.2 0.8 1.3e-05 24.9 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGD97483.1 - 3.8e-10 40.0 0.0 0.0006 19.8 0.0 3.7 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 EGD97483.1 - 6.7e-09 34.9 0.1 0.001 17.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EGD97483.1 - 3.6e-08 33.0 0.0 0.0048 16.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EGD97483.1 - 1.6e-07 30.9 1.6 0.0047 16.6 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain CDC48_2 PF02933.12 EGD97483.1 - 1.8e-07 30.6 0.0 4.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EGD97483.1 - 1.8e-07 31.0 0.0 0.007 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EGD97483.1 - 2.4e-07 30.0 0.0 0.0061 15.6 0.0 2.9 3 0 0 3 3 2 2 Zeta toxin Mg_chelatase PF01078.16 EGD97483.1 - 3.6e-07 29.5 0.4 0.028 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EGD97483.1 - 1e-06 28.2 10.5 0.019 14.3 0.0 4.9 4 2 2 6 6 4 2 AAA domain KaiC PF06745.8 EGD97483.1 - 1.2e-06 27.8 1.2 0.54 9.3 0.0 3.5 2 1 1 3 3 3 2 KaiC RNA_helicase PF00910.17 EGD97483.1 - 1.5e-06 28.2 0.0 0.023 14.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EGD97483.1 - 2.9e-06 27.5 0.0 0.066 13.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EGD97483.1 - 3.5e-06 26.9 0.0 0.0047 16.7 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EGD97483.1 - 8.5e-06 25.8 0.0 0.18 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EGD97483.1 - 1.6e-05 23.9 0.0 0.0058 15.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EGD97483.1 - 4e-05 23.9 0.0 0.22 11.8 0.0 3.3 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.11 EGD97483.1 - 4.3e-05 22.8 0.4 0.22 10.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 EGD97483.1 - 5.2e-05 22.9 0.4 0.14 11.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 EGD97483.1 - 5.5e-05 22.7 0.1 0.59 9.5 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EGD97483.1 - 6.8e-05 22.9 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EGD97483.1 - 8.8e-05 21.5 0.1 0.084 11.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EGD97483.1 - 0.00013 21.7 0.1 5.8 6.5 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase Bac_DnaA PF00308.13 EGD97483.1 - 0.00037 20.2 0.0 1.3 8.5 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein Vps4_C PF09336.5 EGD97483.1 - 0.00039 20.2 0.3 0.0019 18.0 0.1 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 EGD97483.1 - 0.00052 19.6 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EGD97483.1 - 0.0006 19.4 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EGD97483.1 - 0.00063 19.4 0.1 0.85 9.2 0.0 3.5 3 1 1 4 4 3 1 NACHT domain DUF2075 PF09848.4 EGD97483.1 - 0.0013 17.8 0.0 0.57 9.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EGD97483.1 - 0.0013 18.3 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EGD97483.1 - 0.0021 17.7 1.1 1 9.0 0.0 4.1 5 0 0 5 5 3 1 NTPase NB-ARC PF00931.17 EGD97483.1 - 0.004 16.0 0.1 0.59 8.9 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain Viral_helicase1 PF01443.13 EGD97483.1 - 0.0066 15.9 0.0 0.55 9.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase LXG PF04740.7 EGD97483.1 - 0.0097 15.7 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 1 LXG domain of WXG superfamily KAP_NTPase PF07693.9 EGD97483.1 - 0.017 14.1 0.0 0.81 8.6 0.0 2.7 2 1 0 3 3 3 0 KAP family P-loop domain T2SE PF00437.15 EGD97483.1 - 0.017 14.0 0.0 1.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.11 EGD97483.1 - 0.024 13.8 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_10 PF12846.2 EGD97483.1 - 0.058 12.8 1.1 10 5.4 0.0 3.6 3 1 0 4 4 4 0 AAA-like domain Cytidylate_kin2 PF13189.1 EGD97483.1 - 0.06 13.2 1.0 5.1 6.9 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase-like family Zot PF05707.7 EGD97483.1 - 0.083 12.3 0.1 25 4.2 0.0 3.8 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) SKI PF01202.17 EGD97483.1 - 0.09 12.6 0.0 9.1 6.1 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase eIF-1a PF01176.14 EGD97483.1 - 0.12 11.8 0.5 1.4 8.4 0.1 2.6 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 KTI12 PF08433.5 EGD97483.1 - 0.12 11.5 0.0 19 4.3 0.0 2.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 EGD97483.1 - 0.14 11.8 0.1 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF3217 PF11506.3 EGD97485.1 - 0.052 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3217) PsiF_repeat PF07769.9 EGD97486.1 - 0.061 12.8 0.1 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 psiF repeat PEX11 PF05648.9 EGD97488.1 - 6.1e-18 64.9 1.9 3e-15 56.1 0.2 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) DUF331 PF03889.8 EGD97490.1 - 0.21 10.9 1.3 0.36 10.1 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function Mpv17_PMP22 PF04117.7 EGD97491.1 - 3.6e-14 52.1 1.0 2.1e-11 43.3 0.3 2.2 2 0 0 2 2 2 2 Mpv17 / PMP22 family UPF0154 PF03672.8 EGD97491.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) SprT-like PF10263.4 EGD97492.1 - 2.3e-07 30.5 1.5 3.2e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 SprT-like family DUF2946 PF11162.3 EGD97492.1 - 0.035 14.3 6.4 0.073 13.2 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Cullin_binding PF03556.10 EGD97493.1 - 6.7e-30 103.6 3.2 9e-30 103.2 2.2 1.2 1 0 0 1 1 1 1 Cullin binding UPF0113 PF03657.8 EGD97494.1 - 5.7e-06 26.0 0.0 8.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 EGD97494.1 - 0.067 13.2 0.0 0.17 11.9 0.0 1.7 1 1 1 2 2 2 0 pre-rRNA processing and ribosome biogenesis PUA PF01472.15 EGD97494.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 PUA domain NOC3p PF07540.6 EGD97495.1 - 3.8e-33 113.6 0.3 3e-32 110.7 0.3 2.4 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 EGD97495.1 - 2.3e-32 111.7 0.0 6.6e-30 103.7 0.0 2.5 1 1 1 2 2 2 2 CBF/Mak21 family Adaptin_N PF01602.15 EGD97495.1 - 0.012 13.9 1.2 5.8 5.1 0.0 3.0 3 0 0 3 3 3 0 Adaptin N terminal region LTP_2 PF14368.1 EGD97495.1 - 0.06 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Probable lipid transfer DUF1349 PF07081.6 EGD97498.1 - 1.8e-19 69.7 0.0 6.3e-08 32.1 0.0 3.2 3 1 0 3 3 3 2 Protein of unknown function (DUF1349) Cript PF10235.4 EGD97499.1 - 2.3e-32 111.1 7.7 2.3e-32 111.1 5.3 1.7 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.2 EGD97499.1 - 0.00046 19.9 11.7 0.013 15.3 5.7 2.9 2 1 1 3 3 3 2 Double zinc ribbon Yippee-Mis18 PF03226.9 EGD97499.1 - 0.0033 17.4 2.4 0.019 15.0 1.7 2.0 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-ribbon_3 PF13248.1 EGD97499.1 - 0.0049 16.0 8.1 0.29 10.3 1.0 3.3 3 0 0 3 3 3 1 zinc-ribbon domain DUF1272 PF06906.6 EGD97499.1 - 0.74 9.7 7.8 0.27 11.1 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) LIM PF00412.17 EGD97499.1 - 2.2 8.4 11.3 2.5 8.2 0.1 3.6 3 1 0 3 3 3 0 LIM domain FYVE PF01363.16 EGD97499.1 - 4.9 7.1 12.1 8.9 6.2 4.7 2.4 1 1 1 2 2 2 0 FYVE zinc finger DUF2039 PF10217.4 EGD97499.1 - 8.1 6.5 18.5 2.9 7.9 7.8 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) MRP-L46 PF11788.3 EGD97500.1 - 1.1e-34 119.4 0.3 1.8e-34 118.7 0.2 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EGD97500.1 - 0.0029 17.2 0.0 0.0065 16.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain TFIIF_alpha PF05793.7 EGD97501.1 - 0.0014 17.0 16.5 0.0022 16.4 11.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF572 PF04502.8 EGD97501.1 - 0.078 12.1 18.9 0.15 11.2 13.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.2 EGD97501.1 - 0.09 10.4 10.6 0.13 9.9 7.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1777 PF08648.7 EGD97501.1 - 0.091 12.4 15.0 0.16 11.7 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF4407 PF14362.1 EGD97501.1 - 0.18 10.7 4.1 0.26 10.1 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAPS PF04499.10 EGD97501.1 - 0.29 9.6 11.4 0.53 8.8 7.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.6 EGD97501.1 - 1.1 7.3 16.4 1.6 6.8 11.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1266 PF06889.6 EGD97501.1 - 1.2 8.8 8.5 2.4 7.9 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) OmpH PF03938.9 EGD97501.1 - 1.7 8.5 15.3 3.4 7.5 10.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1682 PF07946.9 EGD97501.1 - 1.9 7.2 16.3 3.7 6.3 11.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CCDC66 PF15236.1 EGD97501.1 - 2 7.9 34.4 0.42 10.2 20.9 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 Zip PF02535.17 EGD97501.1 - 3.4 6.5 5.7 6.5 5.6 4.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.11 EGD97501.1 - 3.4 6.5 10.1 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF1675 PF07897.6 EGD97501.1 - 3.7 7.3 15.7 9.6 5.9 10.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SRP-alpha_N PF04086.8 EGD97501.1 - 4.7 6.4 24.0 8.1 5.7 16.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ycf1 PF05758.7 EGD97501.1 - 8.4 3.9 14.4 11 3.5 10.0 1.2 1 0 0 1 1 1 0 Ycf1 CAF1 PF04857.15 EGD97502.1 - 4.6e-48 163.8 0.0 5.9e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease HDA2-3 PF11496.3 EGD97502.1 - 0.036 12.8 0.0 0.072 11.8 0.0 1.4 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 DNA_pol_A_exo1 PF01612.15 EGD97502.1 - 0.1 12.0 0.0 0.67 9.4 0.0 2.4 3 1 0 3 3 3 0 3'-5' exonuclease Mito_carr PF00153.22 EGD97503.1 - 1.2e-67 223.5 1.8 5.4e-22 77.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.15 EGD97504.1 - 1.7e-18 66.7 0.0 7.2e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein PHF5 PF03660.9 EGD97505.1 - 2.8e-51 172.0 9.7 3.2e-51 171.8 6.7 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EGD97505.1 - 0.55 10.0 15.1 0.09 12.6 5.1 2.7 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EGD97505.1 - 2.8 7.7 16.6 6.9 6.4 0.5 3.0 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 EGD97505.1 - 3.5 5.1 5.3 3.6 5.1 3.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Pkinase PF00069.20 EGD97506.1 - 1.9e-21 76.3 0.0 3.5e-21 75.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97506.1 - 3.3e-11 42.7 0.0 7.1e-11 41.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD97506.1 - 0.0058 16.4 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD97506.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EGD97506.1 - 0.059 12.4 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Antimicrobial15 PF08110.7 EGD97506.1 - 0.085 12.9 0.5 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Ocellatin family ketoacyl-synt PF00109.21 EGD97507.1 - 5.5e-70 235.7 0.0 8.9e-70 235.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGD97507.1 - 2.9e-32 110.9 0.0 6.8e-32 109.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EGD97507.1 - 3.2e-30 105.5 0.0 7e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EGD97507.1 - 8.1e-22 77.3 0.0 2.1e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EGD97507.1 - 2.4e-13 50.3 0.0 5.9e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD97507.1 - 2.4e-11 43.4 0.0 6.2e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGD97507.1 - 1.5e-09 37.9 0.4 4.4e-09 36.4 0.2 1.9 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EGD97507.1 - 1.2e-08 34.8 0.0 8.2e-08 32.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD97507.1 - 2.2e-08 34.4 0.0 9.2e-08 32.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD97507.1 - 1.6e-06 28.4 0.0 4.3e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EGD97507.1 - 5.7e-06 25.9 0.0 1.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.13 EGD97507.1 - 1.1e-05 24.7 0.0 0.00048 19.3 0.0 3.3 4 0 0 4 4 4 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGD97507.1 - 1.5e-05 25.5 0.0 4.3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGD97507.1 - 3.8e-05 22.8 0.4 8.6e-05 21.6 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short PF00106.20 EGD97507.1 - 9.3e-05 22.3 0.0 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_32 PF13679.1 EGD97507.1 - 0.00011 21.9 0.0 0.00028 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 EGD97507.1 - 0.0017 17.3 0.1 0.027 13.3 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Methyltransf_26 PF13659.1 EGD97507.1 - 0.0022 17.9 0.0 0.0062 16.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EGD97507.1 - 0.0092 15.0 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase RmlD_sub_bind PF04321.12 EGD97507.1 - 0.018 13.9 0.0 4.8 5.9 0.0 3.0 3 0 0 3 3 3 0 RmlD substrate binding domain KR PF08659.5 EGD97507.1 - 0.044 13.4 0.1 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 KR domain Abhydrolase_5 PF12695.2 EGD97507.1 - 0.059 13.1 0.0 1.8 8.3 0.0 2.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family DXP_reductoisom PF02670.11 EGD97507.1 - 0.066 13.7 0.4 0.24 11.9 0.1 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NodS PF05401.6 EGD97507.1 - 0.19 11.0 0.0 0.44 9.9 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Terminase_4 PF05119.7 EGD97507.1 - 0.21 11.7 0.0 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Phage terminase, small subunit 3Beta_HSD PF01073.14 EGD97507.1 - 0.38 9.4 0.5 1.2 7.7 0.0 2.1 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family p450 PF00067.17 EGD97508.1 - 2.1e-56 191.3 0.0 2.7e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EGD97509.1 - 1.4e-37 129.2 49.1 7e-37 126.9 34.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD97509.1 - 5.7e-12 44.6 10.4 8.8e-12 44.0 7.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Myb_DNA-bind_6 PF13921.1 EGD97510.1 - 9.8e-26 89.6 12.3 1.2e-13 50.9 0.7 3.9 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD97510.1 - 2.2e-19 69.2 15.8 2.8e-09 36.8 0.4 4.1 4 0 0 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EGD97510.1 - 0.013 15.3 7.6 3.7 7.4 0.2 3.5 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.4 EGD97510.1 - 1.1 9.5 7.0 8.5 6.6 0.1 4.0 3 2 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DIOX_N PF14226.1 EGD97511.1 - 2.2e-28 99.1 0.0 3.7e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGD97511.1 - 2.8e-20 72.4 0.0 6.7e-20 71.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF2141 PF09912.4 EGD97511.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) Pinin_SDK_memA PF04696.8 EGD97512.1 - 9.5e-25 86.6 4.7 1.2e-24 86.3 2.9 1.4 1 1 0 1 1 1 1 pinin/SDK/memA/ protein conserved region Abhydrolase_6 PF12697.2 EGD97513.1 - 3e-11 43.6 0.0 3.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD97513.1 - 8.2e-06 25.5 0.0 2.6e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Saccharop_dh PF03435.13 EGD97514.1 - 1.2e-19 70.6 0.0 1.6e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EGD97514.1 - 0.018 15.3 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EGD97514.1 - 0.022 14.7 0.1 0.092 12.7 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding DapB_N PF01113.15 EGD97514.1 - 0.028 14.3 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF3150 PF11348.3 EGD97514.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Ribosomal_L37ae PF01780.14 EGD97515.1 - 1.1e-39 134.1 11.3 1.2e-39 134.0 7.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EGD97515.1 - 0.00091 18.9 2.4 0.0014 18.4 1.7 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 EGD97515.1 - 0.014 15.1 3.1 0.5 10.1 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger GCC2_GCC3 PF07699.8 EGD97515.1 - 0.034 13.7 0.2 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 NOB1_Zn_bind PF08772.6 EGD97515.1 - 0.098 12.4 3.7 0.73 9.7 2.6 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like A2L_zn_ribbon PF08792.5 EGD97515.1 - 0.11 11.9 2.1 0.42 10.1 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain NMDAR2_C PF10565.4 EGD97515.1 - 0.18 10.4 0.6 0.19 10.3 0.4 1.0 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus zf-Sec23_Sec24 PF04810.10 EGD97515.1 - 3 7.4 6.0 1.4 8.5 0.1 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger PHD PF00628.24 EGD97516.1 - 2.4e-09 36.7 8.5 2.4e-09 36.7 5.9 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EGD97516.1 - 2.8e-09 36.6 1.6 2.8e-09 36.6 1.1 3.5 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EGD97516.1 - 1.1e-06 28.6 0.7 1.1e-06 28.6 0.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGD97516.1 - 4.3e-06 26.6 1.4 4.3e-06 26.6 0.9 3.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD97516.1 - 4.3e-06 26.3 1.8 4.3e-06 26.3 1.3 2.8 2 2 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD97516.1 - 1.3e-05 24.7 3.4 1.3e-05 24.7 2.4 2.9 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD97516.1 - 5.3e-05 22.8 5.7 5.3e-05 22.8 4.0 3.1 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EGD97516.1 - 5.7e-05 22.3 3.7 0.00013 21.2 2.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-Apc11 PF12861.2 EGD97516.1 - 0.0004 20.1 0.3 0.0004 20.1 0.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EGD97516.1 - 0.011 15.2 2.8 0.023 14.2 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-PHD-like PF15446.1 EGD97516.1 - 0.016 14.5 1.3 0.016 14.5 0.9 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_UBOX PF13445.1 EGD97516.1 - 0.025 14.2 1.6 0.66 9.7 0.0 2.8 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 EGD97516.1 - 0.93 9.1 7.3 0.076 12.6 0.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ank_5 PF13857.1 EGD97517.1 - 3.3e-13 49.3 1.1 7.6e-09 35.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGD97517.1 - 2e-12 47.2 0.0 1.2e-11 44.8 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGD97517.1 - 2.9e-12 45.7 0.1 5.5e-10 38.5 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EGD97517.1 - 2.1e-09 36.6 0.0 1.2e-07 31.2 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EGD97517.1 - 1.1e-06 29.0 0.0 2.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD97518.1 - 6.4e-19 67.5 1.7 3.1e-09 36.7 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGD97518.1 - 1.1e-18 67.3 0.2 5.5e-07 29.8 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD97518.1 - 2.7e-16 59.5 0.2 1.1e-07 32.1 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EGD97518.1 - 2.9e-13 48.8 0.6 0.00033 20.3 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EGD97518.1 - 4.7e-12 44.9 0.3 0.042 14.0 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat Phlebovirus_G1 PF07243.6 EGD97518.1 - 0.0048 15.1 0.0 0.0061 14.7 0.0 1.1 1 0 0 1 1 1 1 Phlebovirus glycoprotein G1 UDPG_MGDP_dh_C PF03720.10 EGD97518.1 - 0.043 13.9 0.1 0.45 10.6 0.0 2.3 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain MFS_1 PF07690.11 EGD97519.1 - 5.9e-38 130.4 34.7 5.9e-38 130.4 24.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily HEAT_2 PF13646.1 EGD97520.1 - 3.4e-09 36.8 5.8 3.1e-06 27.3 0.4 4.2 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 EGD97520.1 - 0.00014 21.6 9.8 0.1 12.7 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EGD97520.1 - 0.00062 20.1 9.2 0.026 15.0 0.4 5.0 5 0 0 5 5 5 2 HEAT-like repeat CLASP_N PF12348.3 EGD97520.1 - 0.019 14.3 0.0 0.54 9.5 0.0 2.8 1 1 1 2 2 2 0 CLASP N terminal SNF5 PF04855.7 EGD97521.1 - 2.3e-76 256.4 0.4 4.4e-76 255.5 0.0 1.6 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Exo_endo_phos PF03372.18 EGD97522.1 - 2.4e-12 47.3 0.1 2.8e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EGD97522.1 - 0.00084 18.9 0.0 0.0018 17.8 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Peptidase_M24 PF00557.19 EGD97523.1 - 7e-13 48.6 0.0 8.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 S-antigen PF05756.6 EGD97523.1 - 0.55 10.2 3.6 1.2 9.1 2.5 1.6 1 0 0 1 1 1 0 S-antigen protein PHD PF00628.24 EGD97524.1 - 5.3e-18 64.4 16.1 1.2e-11 44.0 4.7 2.4 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 EGD97524.1 - 0.0026 17.0 5.9 0.7 9.1 1.5 3.1 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EGD97524.1 - 1.9 8.2 7.3 10 5.9 0.9 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EGD97524.1 - 2.2 7.6 9.3 1.9 7.8 1.0 3.2 3 0 0 3 3 3 0 PHD-finger Lectin_leg-like PF03388.8 EGD97525.1 - 7.9e-25 87.3 0.0 1.1e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family TMF_TATA_bd PF12325.3 EGD97525.1 - 0.0061 16.2 1.7 0.0097 15.6 1.1 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding ALMT PF11744.3 EGD97525.1 - 0.013 14.2 0.1 0.017 13.7 0.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TBPIP PF07106.8 EGD97525.1 - 0.071 12.6 1.6 0.11 12.0 1.1 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EGD97525.1 - 0.48 10.7 2.3 0.99 9.7 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) YlbD_coat PF14071.1 EGD97525.1 - 4 7.5 5.7 3.6 7.6 0.6 2.2 1 1 1 2 2 2 0 Putative coat protein Alg6_Alg8 PF03155.10 EGD97526.1 - 3.1e-140 468.1 28.1 4.1e-140 467.7 19.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.4 EGD97527.1 - 3.4e-24 84.9 0.1 1.2e-23 83.1 0.1 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EGD97527.1 - 3.8e-19 68.2 1.6 6.5e-19 67.4 1.1 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EGD97527.1 - 9.6e-12 44.3 0.7 2.3e-11 43.1 0.5 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EGD97527.1 - 4.3e-05 23.2 0.2 0.00012 21.8 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 EGD97527.1 - 0.001 18.8 0.2 0.0037 17.1 0.1 2.1 1 1 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Mito_carr PF00153.22 EGD97528.1 - 3.3e-59 196.5 2.5 1.2e-20 72.9 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Pex2_Pex12 PF04757.9 EGD97529.1 - 2.7e-55 187.2 2.5 3.5e-55 186.9 1.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EGD97529.1 - 1e-06 28.6 3.2 1.7e-06 27.9 1.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGD97529.1 - 1.6e-06 27.8 2.8 2.8e-06 27.0 1.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EGD97529.1 - 0.00051 19.8 2.6 0.0012 18.6 1.8 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGD97529.1 - 0.0028 17.2 1.4 0.0053 16.3 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD97529.1 - 0.093 12.4 0.6 0.19 11.4 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Oligomerisation PF02410.10 EGD97530.1 - 0.00051 20.0 0.0 0.41 10.7 0.1 2.6 2 0 0 2 2 2 2 Oligomerisation domain NMD3 PF04981.8 EGD97531.1 - 4.7e-74 248.4 4.0 6.8e-74 247.9 2.8 1.2 1 0 0 1 1 1 1 NMD3 family HypA PF01155.14 EGD97531.1 - 0.56 9.9 8.6 2.8 7.6 0.9 3.2 3 1 1 4 4 4 0 Hydrogenase expression/synthesis hypA family FYVE PF01363.16 EGD97531.1 - 1.2 9.1 9.2 5 7.0 4.0 2.4 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.2 EGD97531.1 - 8.5 6.2 11.4 1.5e+02 2.3 0.0 2.8 2 1 0 2 2 2 0 Double zinc ribbon RRM_1 PF00076.17 EGD97532.1 - 0.0038 16.8 0.0 0.98 9.0 0.0 2.8 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD97532.1 - 0.014 15.3 0.0 0.046 13.7 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3446 PF11928.3 EGD97532.1 - 0.071 13.3 2.0 0.15 12.2 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) RRM_5 PF13893.1 EGD97532.1 - 0.14 11.9 0.0 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1237 PF06824.6 EGD97533.1 - 1.8e-181 603.3 0.0 2.1e-181 603.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) CDC27 PF09507.5 EGD97534.1 - 7.3e-84 282.4 29.4 8.8e-84 282.2 20.4 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-C3HC4_2 PF13923.1 EGD97535.1 - 2e-08 34.1 24.9 1.3e-07 31.5 12.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD97535.1 - 1.7e-06 27.7 21.8 3.7e-06 26.6 11.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGD97535.1 - 2e-06 27.3 17.0 2e-06 27.3 11.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGD97535.1 - 2.1e-06 27.3 7.4 2.1e-06 27.3 5.1 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EGD97535.1 - 2.6e-06 26.9 13.9 2.6e-06 26.9 9.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD97535.1 - 4.4e-06 26.3 16.7 4.4e-06 26.3 11.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain SAP PF02037.22 EGD97535.1 - 2.2e-05 23.8 0.0 4.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.1 EGD97535.1 - 0.00028 20.6 20.2 0.00063 19.5 11.9 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.10 EGD97535.1 - 0.016 15.1 0.0 0.063 13.2 0.0 2.0 2 0 0 2 2 1 0 U-box domain Rad50_zn_hook PF04423.9 EGD97535.1 - 0.073 12.5 7.6 4.1 6.9 2.0 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Apc11 PF12861.2 EGD97535.1 - 0.16 11.8 5.2 0.41 10.5 3.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGD97535.1 - 0.34 10.6 21.4 0.072 12.8 9.4 3.0 3 0 0 3 3 3 0 RING-type zinc-finger zf-rbx1 PF12678.2 EGD97535.1 - 0.74 9.9 12.3 0.14 12.2 5.5 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger Mob_synth_C PF06463.8 EGD97535.1 - 1.6 8.3 10.2 0.4 10.3 4.6 1.7 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C Snf7 PF03357.16 EGD97536.1 - 6.2e-17 61.5 10.3 6.2e-17 61.5 7.2 2.1 1 1 1 2 2 2 1 Snf7 DUF1729 PF08354.5 EGD97536.1 - 0.098 12.4 0.2 0.29 10.9 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) TRAPPC-Trs85 PF12739.2 EGD97539.1 - 1.4e-121 406.0 0.1 4.8e-120 400.9 0.0 2.0 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit PolyA_pol PF01743.15 EGD97540.1 - 4e-23 81.9 0.0 9.1e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EGD97540.1 - 3.7e-07 29.5 0.0 9.4e-07 28.3 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EGD97540.1 - 0.00066 19.5 0.1 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative DUF2454 PF10521.4 EGD97541.1 - 6.3e-83 278.0 0.8 1.1e-82 277.2 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Syja_N PF02383.13 EGD97542.1 - 1e-90 303.7 0.0 1.8e-90 302.9 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain LIP PF03583.9 EGD97543.1 - 1.5e-81 273.7 0.0 1.9e-81 273.4 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 EGD97543.1 - 0.00044 20.1 0.0 0.00071 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_47 PF01532.15 EGD97544.1 - 6.9e-176 585.3 0.0 8.1e-176 585.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 IBV_3C PF03620.8 EGD97545.1 - 0.0044 16.9 0.3 0.016 15.0 0.1 2.0 2 0 0 2 2 2 1 IBV 3C protein DUF1772 PF08592.6 EGD97545.1 - 0.034 13.8 0.9 0.057 13.1 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Pkinase PF00069.20 EGD97546.1 - 2.7e-32 111.9 0.0 6.8e-19 68.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97546.1 - 5.4e-12 45.3 0.0 3.4e-05 23.0 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Fungal_trans_2 PF11951.3 EGD97547.1 - 3.4e-09 35.7 1.7 4.7e-08 32.0 0.6 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD97547.1 - 5.8e-08 32.5 9.9 9.8e-08 31.7 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol_B PF00136.16 EGD97548.1 - 2e-129 432.4 9.2 1.4e-118 396.6 4.5 2.1 1 1 1 2 2 2 2 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGD97548.1 - 6.1e-82 275.0 1.0 2.4e-81 273.1 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EGD97548.1 - 1e-24 86.3 2.6 2.9e-24 84.8 1.8 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EGD97548.1 - 3.4e-05 23.7 0.2 0.00013 21.8 0.1 2.1 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EGD97548.1 - 0.00079 19.0 0.1 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.17 EGD97548.1 - 0.0056 16.3 6.9 0.025 14.3 0.8 2.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AKNA PF12443.3 EGD97548.1 - 0.013 15.4 1.7 0.028 14.4 0.7 2.0 2 0 0 2 2 2 0 AT-hook-containing transcription factor FAD_binding_3 PF01494.14 EGD97549.1 - 7.6e-15 54.8 0.0 1.2e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGD97549.1 - 1e-05 24.6 0.0 3.4e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD97549.1 - 0.00013 21.9 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EGD97549.1 - 0.00016 20.8 1.5 0.0018 17.4 1.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EGD97549.1 - 0.0009 18.2 0.0 0.0021 17.0 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EGD97549.1 - 0.00092 17.7 0.0 0.0026 16.2 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EGD97549.1 - 0.00098 19.4 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD97549.1 - 0.0017 18.2 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGD97549.1 - 0.024 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 EGD97549.1 - 0.045 12.5 0.0 0.14 10.9 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase DUF1517 PF07466.6 EGD97549.1 - 0.09 11.7 0.2 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) MFS_1 PF07690.11 EGD97550.1 - 1.9e-29 102.5 43.3 2.2e-27 95.6 24.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily AATF-Che1 PF13339.1 EGD97551.1 - 3.2 7.9 8.6 1.1 9.4 1.8 2.6 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor pRN1_helical PF13010.1 EGD97553.1 - 0.085 12.4 0.5 0.16 11.5 0.3 1.5 1 1 0 1 1 1 0 Primase helical domain DUF3618 PF12277.3 EGD97553.1 - 0.97 9.5 5.3 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) zf-C2H2 PF00096.21 EGD97554.1 - 1e-06 28.7 28.0 0.062 13.6 0.1 6.3 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD97554.1 - 3e-06 27.1 21.4 0.45 10.9 0.1 6.5 7 0 0 7 7 7 3 C2H2-type zinc finger zf-met PF12874.2 EGD97554.1 - 8.2e-05 22.6 18.1 0.02 15.0 0.1 5.0 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGD97554.1 - 0.00014 21.9 11.4 0.028 14.5 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGD97554.1 - 0.014 15.2 8.4 0.21 11.5 0.0 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGD97554.1 - 0.8 9.8 22.4 4.4 7.4 0.0 5.1 2 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_5 PF13719.1 EGD97554.1 - 1.8 8.1 9.4 22 4.7 0.7 3.9 3 1 0 3 3 3 0 zinc-ribbon domain zf-CSL PF05207.8 EGD97554.1 - 2.1 7.9 10.1 0.81 9.2 0.1 2.7 2 1 0 2 2 2 0 CSL zinc finger zinc_ribbon_4 PF13717.1 EGD97554.1 - 2.6 7.8 9.8 24 4.7 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain zf-RING_2 PF13639.1 EGD97554.1 - 9.4 6.1 11.6 16 5.4 0.6 3.2 2 1 1 3 3 3 0 Ring finger domain Cyanate_lyase PF02560.9 EGD97555.1 - 1.2e-32 111.2 0.1 1.8e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_26 PF13443.1 EGD97555.1 - 3.3e-05 24.0 0.0 5.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_31 PF13560.1 EGD97555.1 - 0.0002 21.4 0.0 0.00032 20.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 EGD97555.1 - 0.015 15.1 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_19 PF12844.2 EGD97555.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GFA PF04828.9 EGD97556.1 - 3.4e-19 68.5 0.4 5.3e-19 67.9 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PLDc_2 PF13091.1 EGD97557.1 - 3.1e-14 52.8 0.0 3.4e-06 26.8 0.0 3.5 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EGD97557.1 - 6.1e-13 48.1 0.6 5e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EGD97557.1 - 0.12 11.3 0.1 0.59 9.0 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB DUF3317 PF11779.3 EGD97559.1 - 3.8e-05 23.0 3.9 6.5e-05 22.2 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Kinetochor_Ybp2 PF08568.5 EGD97560.1 - 2e-119 399.6 0.3 2.4e-119 399.4 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin GST_C_2 PF13410.1 EGD97561.1 - 0.00014 21.6 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD97561.1 - 0.00086 19.7 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGD97561.1 - 0.0044 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD97561.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Rhomboid PF01694.17 EGD97562.1 - 2.5e-35 121.6 8.6 2.5e-35 121.6 6.0 1.9 2 0 0 2 2 2 1 Rhomboid family Macoilin PF09726.4 EGD97566.1 - 0.31 9.2 2.7 0.36 9.0 1.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3439 PF11921.3 EGD97566.1 - 0.85 9.3 30.9 0.19 11.4 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF1681 PF07933.9 EGD97567.1 - 2.5e-47 160.4 0.1 6.9e-47 158.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) Sporozoite_P67 PF05642.6 EGD97567.1 - 0.0011 16.9 4.5 0.0021 15.9 3.1 1.4 1 1 0 1 1 1 1 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 EGD97567.1 - 0.022 14.3 6.4 0.057 12.9 1.0 2.2 2 0 0 2 2 2 0 Nucleoplasmin LAT PF15234.1 EGD97567.1 - 0.026 14.0 8.8 0.25 10.7 2.1 2.2 2 0 0 2 2 2 0 Linker for activation of T-cells Pox_Ag35 PF03286.9 EGD97567.1 - 0.22 11.0 6.5 2.4 7.6 0.1 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein BSP_II PF05432.6 EGD97567.1 - 0.31 10.2 14.4 0.2 10.8 2.5 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) SR-25 PF10500.4 EGD97567.1 - 0.46 9.9 16.9 0.1 12.0 9.4 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Tim54 PF11711.3 EGD97567.1 - 0.47 8.9 6.5 2.9 6.4 0.5 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 TT_ORF2 PF02957.10 EGD97567.1 - 1.1 9.9 5.4 0.73 10.5 0.5 2.1 2 0 0 2 2 2 0 TT viral ORF2 RNA_polI_A34 PF08208.6 EGD97567.1 - 3.4 7.2 15.0 0.8 9.3 2.3 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 RNA_pol_Rpc4 PF05132.9 EGD97567.1 - 4.2 7.3 9.1 9.7 6.1 0.5 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 TFIIF_alpha PF05793.7 EGD97567.1 - 4.3 5.5 12.0 0.6 8.4 3.6 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IF-2B PF01008.12 EGD97568.1 - 5.3e-51 173.2 0.0 2.6e-50 171.0 0.0 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 EGD97568.1 - 0.0038 16.8 0.0 0.36 10.4 0.0 2.3 2 0 0 2 2 2 2 DeoR C terminal sensor domain TPR_5 PF12688.2 EGD97568.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetratrico peptide repeat Nuf2 PF03800.9 EGD97569.1 - 4.8e-33 114.2 0.1 4.8e-33 114.2 0.0 2.5 3 2 0 3 3 3 1 Nuf2 family DUF3921 PF13060.1 EGD97569.1 - 0.044 13.6 0.2 0.25 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) Reo_sigmaC PF04582.7 EGD97569.1 - 0.26 10.4 9.9 0.42 9.7 2.7 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EGD97569.1 - 1.3 7.9 51.9 3.2 6.6 13.3 2.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EGD97569.1 - 4.8 5.7 47.8 5.2 5.6 10.5 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Spore_coat_CotO PF14153.1 EGD97570.1 - 0.01 15.3 1.7 0.0099 15.3 1.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF2126 PF09899.4 EGD97570.1 - 0.027 12.5 0.4 0.036 12.1 0.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) CDC45 PF02724.9 EGD97570.1 - 0.031 12.3 5.0 0.038 12.0 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 EGD97570.1 - 0.034 13.6 3.3 0.05 13.1 2.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nucleoplasmin PF03066.10 EGD97570.1 - 0.051 13.0 8.8 0.08 12.4 6.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin PTRF_SDPR PF15237.1 EGD97570.1 - 0.06 12.7 2.3 0.086 12.2 1.6 1.2 1 0 0 1 1 1 0 PTRF/SDPR family DUF1510 PF07423.6 EGD97570.1 - 0.21 10.9 9.2 0.3 10.4 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Synuclein PF01387.12 EGD97570.1 - 0.23 11.3 2.3 0.44 10.4 1.6 1.4 1 0 0 1 1 1 0 Synuclein DUF551 PF04448.7 EGD97570.1 - 0.25 12.1 3.7 4.1 8.2 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF551) Tfb4 PF03850.9 EGD97570.1 - 0.28 10.4 1.6 0.4 9.8 1.1 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 BTV_NS2 PF04514.7 EGD97570.1 - 0.32 9.8 5.6 0.45 9.3 3.9 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Daxx PF03344.10 EGD97570.1 - 0.32 9.4 14.3 0.43 8.9 9.9 1.1 1 0 0 1 1 1 0 Daxx Family RNA_pol_3_Rpc31 PF11705.3 EGD97570.1 - 0.34 10.7 11.3 0.5 10.2 7.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CobT PF06213.7 EGD97570.1 - 0.37 9.8 10.1 0.64 9.0 7.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Zip PF02535.17 EGD97570.1 - 0.49 9.3 3.6 0.63 8.9 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter WPP PF13943.1 EGD97570.1 - 0.52 10.5 3.7 0.22 11.7 0.7 1.7 2 1 1 3 3 1 0 WPP domain DUF3449 PF11931.3 EGD97570.1 - 0.6 9.5 7.5 0.91 8.9 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Nucleo_P87 PF07267.6 EGD97570.1 - 0.6 8.7 4.4 0.79 8.3 3.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PPP4R2 PF09184.6 EGD97570.1 - 0.7 9.3 11.7 0.88 9.0 8.1 1.1 1 0 0 1 1 1 0 PPP4R2 PBP1_TM PF14812.1 EGD97570.1 - 0.76 10.1 10.7 0.1 12.8 4.7 1.6 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 EGD97570.1 - 1.8 7.7 9.0 2.6 7.2 6.2 1.1 1 0 0 1 1 1 0 NOA36 protein VID27 PF08553.5 EGD97570.1 - 2 6.5 8.0 2.5 6.2 5.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2457 PF10446.4 EGD97570.1 - 2.1 6.9 14.5 2.9 6.5 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribosomal_60s PF00428.14 EGD97570.1 - 2.4 8.6 15.2 0.79 10.1 7.9 2.1 2 1 0 2 2 2 0 60s Acidic ribosomal protein RXT2_N PF08595.6 EGD97570.1 - 3.6 7.3 10.4 1.6 8.5 5.1 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal TRAP_alpha PF03896.11 EGD97570.1 - 3.6 6.4 9.3 5.4 5.9 6.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Adaptin_N PF01602.15 EGD97571.1 - 2e-98 329.9 0.0 2.4e-98 329.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EGD97571.1 - 6.4e-10 39.1 6.1 0.00033 20.8 0.0 5.0 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.17 EGD97571.1 - 1.2e-07 31.1 0.4 0.2 11.8 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EGD97571.1 - 0.00065 20.1 7.4 1.1 9.8 0.0 5.5 6 1 1 7 7 7 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EGD97571.1 - 0.0038 17.1 0.2 2 8.4 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EGD97571.1 - 0.029 14.2 0.1 12 5.6 0.0 3.4 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EGD97571.1 - 0.046 13.5 2.1 1.8 8.4 0.1 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat VHS PF00790.14 EGD97571.1 - 0.093 12.3 1.4 63 3.1 0.0 4.0 5 0 0 5 5 5 0 VHS domain Paf1 PF03985.8 EGD97571.1 - 0.49 9.0 0.0 0.49 9.0 0.0 2.4 2 0 0 2 2 2 0 Paf1 Metallophos PF00149.23 EGD97572.1 - 6.4e-07 28.9 0.1 8.5e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 EGD97573.1 - 9.4e-61 204.7 0.1 1e-60 204.5 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor GFA PF04828.9 EGD97574.1 - 4.9e-08 32.8 0.3 4.9e-08 32.8 0.2 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EGD97574.1 - 0.0027 17.1 0.1 0.0027 17.1 0.1 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 EGD97574.1 - 0.003 17.2 0.1 0.003 17.2 0.1 2.7 3 0 0 3 3 3 1 Nudix N-terminal zf-ribbon_3 PF13248.1 EGD97574.1 - 0.028 13.6 0.3 0.028 13.6 0.2 2.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-CSL PF05207.8 EGD97574.1 - 0.074 12.5 1.2 0.19 11.2 0.4 2.0 2 0 0 2 2 2 0 CSL zinc finger Cys_rich_CWC PF14375.1 EGD97574.1 - 0.079 12.8 0.5 0.079 12.8 0.4 1.9 2 0 0 2 2 2 0 Cysteine-rich CWC KilA-N PF04383.8 EGD97575.1 - 0.19 11.3 0.4 1.2 8.7 0.0 2.4 2 1 0 2 2 2 0 KilA-N domain Clp1 PF06807.9 EGD97576.1 - 4.5e-15 55.9 0.0 8.4e-14 51.7 0.0 2.5 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EGD97576.1 - 3e-07 30.2 0.0 4.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EGD97576.1 - 0.00011 21.8 0.0 0.0021 17.6 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EGD97576.1 - 0.0016 18.4 0.0 0.0073 16.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGD97576.1 - 0.026 14.8 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.4 EGD97576.1 - 0.079 12.4 0.0 0.49 9.8 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGD97576.1 - 0.16 11.2 0.0 0.39 9.9 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_35 PF14516.1 EGD97576.1 - 0.29 9.7 0.0 0.43 9.1 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain ADH_zinc_N PF00107.21 EGD97578.1 - 8.5e-30 102.9 0.0 1.4e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGD97578.1 - 1.8e-20 74.1 0.0 3.4e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD97578.1 - 1.4e-08 34.4 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Arb1 PF09692.5 EGD97579.1 - 2e-101 339.7 0.1 1.9e-65 221.2 0.0 2.0 1 1 1 2 2 2 2 Argonaute siRNA chaperone (ARC) complex subunit Arb1 PG_binding_1 PF01471.13 EGD97579.1 - 0.081 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative peptidoglycan binding domain IPK PF03770.11 EGD97580.1 - 1e-60 204.7 0.0 1.3e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_S19 PF00203.16 EGD97581.1 - 1.3e-21 75.9 0.0 1.5e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 EGD97582.1 - 2.5e-23 81.6 0.1 4e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 EGD97582.1 - 0.29 11.6 1.4 0.92 10.0 1.0 1.9 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TRF PF08558.5 EGD97583.1 - 2.4e-80 269.3 0.4 4.6e-80 268.4 0.3 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EGD97583.1 - 1.7e-05 24.7 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Zip PF02535.17 EGD97583.1 - 2.9 6.7 8.1 0.93 8.4 2.6 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter His_Phos_2 PF00328.17 EGD97584.1 - 1.6e-09 37.5 0.0 2.9e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HR1 PF02185.11 EGD97585.1 - 0.045 13.5 0.2 0.098 12.4 0.1 1.5 1 0 0 1 1 1 0 Hr1 repeat MFS_1 PF07690.11 EGD97586.1 - 8.1e-30 103.7 53.6 2.6e-26 92.1 38.3 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF997 PF06196.7 EGD97586.1 - 0.19 11.2 0.0 0.19 11.2 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF997) DUF4006 PF13179.1 EGD97586.1 - 1.1 8.8 5.2 0.32 10.5 0.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF4267 PF14087.1 EGD97588.1 - 2e-28 98.2 4.3 2.3e-28 98.0 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF998 PF06197.8 EGD97588.1 - 0.036 13.3 12.2 0.1 11.9 8.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Pkinase PF00069.20 EGD97589.1 - 5e-71 238.8 0.0 9.2e-71 238.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97589.1 - 1.2e-31 109.7 0.0 7e-23 81.0 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGD97589.1 - 4.8e-06 25.7 0.0 0.27 10.1 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EGD97589.1 - 0.027 13.5 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD97589.1 - 0.057 13.1 0.0 4.4 6.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nucleoplasmin PF03066.10 EGD97590.1 - 0.0026 17.2 0.6 0.0028 17.1 0.4 1.2 1 0 0 1 1 1 1 Nucleoplasmin Roughex PF06020.6 EGD97590.1 - 0.009 14.7 2.6 0.011 14.4 1.8 1.1 1 0 0 1 1 1 1 Drosophila roughex protein PBP1_TM PF14812.1 EGD97590.1 - 0.044 14.0 6.6 0.044 14.0 4.6 2.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 EGD97590.1 - 0.16 11.1 3.6 0.19 10.8 2.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DASH_Dad3 PF08656.5 EGD97591.1 - 3.9e-27 93.7 1.4 4.4e-27 93.5 1.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 Peptidase_M75 PF09375.5 EGD97591.1 - 0.035 13.4 0.2 0.036 13.3 0.1 1.1 1 0 0 1 1 1 0 Imelysin RINT1_TIP1 PF04437.8 EGD97591.1 - 0.057 11.9 0.5 0.07 11.6 0.4 1.0 1 0 0 1 1 1 0 RINT-1 / TIP-1 family Baculo_gp41 PF04700.7 EGD97591.1 - 0.077 12.4 0.1 0.085 12.2 0.1 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Ribosomal_S5_C PF03719.10 EGD97592.1 - 2.7e-20 71.4 0.1 3.2e-19 67.9 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EGD97592.1 - 9.9e-13 47.6 0.2 2.5e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain ISN1 PF06437.6 EGD97592.1 - 0.061 12.0 0.0 0.099 11.3 0.0 1.3 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase CRAL_TRIO PF00650.15 EGD97594.1 - 0.0049 16.3 0.0 0.013 14.9 0.0 1.8 1 1 0 1 1 1 1 CRAL/TRIO domain tRNA_U5-meth_tr PF05958.6 EGD97595.1 - 3.4e-16 58.8 0.1 3.2e-14 52.3 0.0 2.6 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EGD97595.1 - 1.4e-06 27.9 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 EGD97595.1 - 3.6e-05 23.4 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 TRAM domain Methyltransf_15 PF09445.5 EGD97595.1 - 0.00019 21.0 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EGD97595.1 - 0.00067 20.2 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD97595.1 - 0.0019 18.6 0.1 0.032 14.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD97595.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EGD97595.1 - 0.028 13.5 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGD97595.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Actin PF00022.14 EGD97596.1 - 5e-90 301.7 0.0 8.2e-90 301.0 0.0 1.3 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGD97596.1 - 0.00012 20.8 0.1 0.0038 15.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Asparaginase_2 PF01112.13 EGD97597.1 - 2e-37 128.6 5.8 7.3e-23 80.7 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.9 EGD97598.1 - 2.9e-110 367.8 0.0 3.7e-110 367.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C2HC5 PF06221.8 EGD97598.1 - 0.29 10.9 5.2 0.56 10.0 3.6 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF1180 PF06679.7 EGD97598.1 - 5.4 6.8 7.8 7.9 6.3 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) UNC45-central PF11701.3 EGD97599.1 - 2.9e-42 143.9 2.3 6.2e-39 133.1 0.2 3.7 4 0 0 4 4 4 2 Myosin-binding striated muscle assembly central Atx10homo_assoc PF09759.4 EGD97599.1 - 0.0025 17.5 0.0 1 9.1 0.0 3.0 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain PUL PF08324.6 EGD97599.1 - 0.0078 15.0 0.0 0.087 11.5 0.0 2.6 3 0 0 3 3 3 1 PUL domain Peptidase_S9 PF00326.16 EGD97599.1 - 0.17 11.1 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4286 PF14114.1 EGD97599.1 - 0.18 12.1 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Arm PF00514.18 EGD97599.1 - 0.37 10.7 13.8 11 6.0 0.0 7.4 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Trp_halogenase PF04820.9 EGD97600.1 - 1.1e-28 100.1 0.2 6.4e-14 51.4 0.0 2.8 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EGD97600.1 - 4e-08 32.7 0.0 1.4e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGD97600.1 - 7.4e-05 22.7 0.2 7.4e-05 22.7 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGD97600.1 - 0.00026 20.9 0.0 0.00063 19.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD97600.1 - 0.00027 19.9 0.3 0.00088 18.2 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGD97600.1 - 0.00036 19.7 0.8 0.0013 17.8 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EGD97600.1 - 0.0011 17.9 0.1 0.0024 16.8 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EGD97600.1 - 0.0021 16.6 0.1 0.004 15.6 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein TrkA_N PF02254.13 EGD97600.1 - 0.0077 16.2 0.1 2.7 8.0 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_3 PF13738.1 EGD97600.1 - 0.0099 15.9 0.0 0.021 14.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGD97600.1 - 0.01 14.7 1.0 0.024 13.4 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EGD97600.1 - 0.045 12.8 0.1 0.19 10.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EGD97600.1 - 0.11 12.9 0.1 0.39 11.1 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 EGD97601.1 - 3.9e-27 94.9 0.0 5.3e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGD97602.1 - 2.8e-71 240.4 0.0 5.1e-71 239.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 UPF0203 PF05254.7 EGD97602.1 - 0.036 13.9 0.5 4.8 7.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) KGG PF10685.4 EGD97602.1 - 0.28 11.1 1.2 0.54 10.2 0.8 1.4 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif Myf5 PF12232.3 EGD97603.1 - 0.089 13.4 1.6 0.14 12.7 1.1 1.3 1 0 0 1 1 1 0 Myogenic determination factor 5 AIG2_2 PF13772.1 EGD97605.1 - 7.5e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family MFS_1 PF07690.11 EGD97606.1 - 3.3e-45 154.3 45.3 3.3e-45 154.3 31.4 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD97606.1 - 1.4e-19 69.7 14.9 3.1e-19 68.6 10.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGD97606.1 - 2.7e-13 49.3 11.0 2.7e-13 49.3 7.6 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter DUF1422 PF07226.6 EGD97606.1 - 0.0013 18.4 0.5 0.0013 18.4 0.4 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1422) ABC_tran PF00005.22 EGD97607.1 - 3.1e-32 111.7 0.0 6e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGD97607.1 - 3.1e-18 66.1 15.7 4.9e-18 65.5 10.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EGD97607.1 - 2.7e-07 30.0 0.1 0.00048 19.4 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD97607.1 - 3.1e-07 30.6 0.0 0.0006 19.8 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGD97607.1 - 0.00041 19.8 0.2 0.0011 18.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGD97607.1 - 0.00086 19.4 0.2 0.0054 16.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGD97607.1 - 0.00094 18.6 0.3 0.0076 15.7 0.1 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EGD97607.1 - 0.0016 18.4 0.2 0.0047 16.9 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 EGD97607.1 - 0.0026 16.8 0.0 0.045 12.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 EGD97607.1 - 0.0033 17.3 0.2 0.063 13.1 0.2 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EGD97607.1 - 0.0068 16.7 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGD97607.1 - 0.008 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGD97607.1 - 0.022 14.1 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EGD97607.1 - 0.05 13.4 0.4 0.12 12.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 EGD97607.1 - 0.062 14.1 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGD97607.1 - 0.099 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.16 EGD97608.1 - 2.7e-41 141.7 0.0 3.2e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD97608.1 - 0.039 13.0 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase MBOAT_2 PF13813.1 EGD97609.1 - 1.2e-23 82.9 1.2 2.2e-23 82.1 0.8 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.17 EGD97610.1 - 6.9e-36 123.7 0.0 9.4e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.9 EGD97611.1 - 1.4e-19 70.7 0.0 1.9e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD97611.1 - 3.2e-05 23.7 0.4 0.21 11.3 0.2 3.4 2 2 2 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.19 EGD97611.1 - 0.00069 18.6 0.5 0.0016 17.4 0.0 1.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD97611.1 - 0.00099 18.0 0.1 0.0022 16.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGD97611.1 - 0.0012 18.7 0.4 0.0026 17.7 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGD97611.1 - 0.0033 17.5 0.5 1 9.3 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD97611.1 - 0.025 13.0 0.2 0.11 10.9 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 EGD97611.1 - 0.032 13.2 0.2 0.092 11.7 0.1 1.7 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EGD97611.1 - 0.034 13.0 0.0 0.066 12.0 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EGD97613.1 - 2.3e-12 47.2 0.0 2.9e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGD97613.1 - 0.00067 18.8 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EGD97613.1 - 0.00071 19.7 0.1 0.022 14.8 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGD97613.1 - 0.0015 17.4 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGD97613.1 - 0.0031 16.0 0.2 0.018 13.5 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EGD97613.1 - 0.0042 17.0 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGD97613.1 - 0.018 14.7 3.6 0.29 10.9 0.4 2.4 1 1 1 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 EGD97613.1 - 0.06 12.2 1.2 0.081 11.8 0.8 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EGD97613.1 - 0.064 13.5 0.0 0.18 12.0 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.17 EGD97613.1 - 0.067 12.0 0.1 0.24 10.2 0.0 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EGD97613.1 - 1 8.3 5.4 0.8 8.7 2.6 1.6 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGD97614.1 - 2.1e-15 57.1 0.0 2.8e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD97614.1 - 6e-05 22.1 0.1 0.00013 20.9 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EGD97614.1 - 8.3e-05 21.6 0.2 0.00032 19.6 0.1 1.8 1 1 1 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EGD97614.1 - 0.00014 20.6 0.0 0.00038 19.2 0.0 1.6 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EGD97614.1 - 0.00018 21.4 0.8 0.0005 20.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGD97614.1 - 0.00077 18.0 0.0 0.0046 15.4 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EGD97614.1 - 0.0015 18.3 0.0 2.2 8.0 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EGD97614.1 - 0.0023 16.8 0.0 0.0052 15.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EGD97614.1 - 0.0068 15.4 0.1 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGD97614.1 - 0.0098 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EGD97614.1 - 0.02 13.8 0.0 0.073 11.9 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EGD97614.1 - 0.088 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD97614.1 - 0.15 11.1 1.6 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Methyltransf_2 PF00891.13 EGD97615.1 - 3.9e-38 131.0 0.0 5.2e-38 130.6 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGD97615.1 - 0.00016 21.4 0.1 0.00038 20.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain GST_C PF00043.20 EGD97616.1 - 8.7e-07 28.8 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGD97616.1 - 4.9e-05 23.1 0.1 0.0001 22.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGD97616.1 - 7.6e-05 22.6 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGD97616.1 - 0.00017 21.7 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGD97616.1 - 0.0002 21.7 0.3 0.00032 21.1 0.2 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD97616.1 - 0.0035 17.4 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain p450 PF00067.17 EGD97617.1 - 4.6e-51 173.7 0.0 6.2e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M19 PF01244.16 EGD97618.1 - 6.1e-102 340.8 0.0 7.1e-102 340.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) HAS-barrel PF09378.5 EGD97618.1 - 0.041 13.7 0.0 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 HAS barrel domain DUF2113 PF09886.4 EGD97618.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) Stig1 PF04885.8 EGD97619.1 - 3.8e-35 121.0 201.2 5.3e-05 23.4 11.8 9.2 1 1 8 9 9 9 9 Stigma-specific protein, Stig1 AMP-binding PF00501.23 EGD97620.1 - 7.1e-84 281.5 0.0 1.1e-83 281.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGD97620.1 - 8.7e-44 149.5 0.0 9.2e-24 83.8 0.0 2.5 2 0 0 2 2 2 2 Condensation domain HxxPF_rpt PF13745.1 EGD97620.1 - 5.7e-08 32.9 0.0 4.9e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 HxxPF-repeated domain PP-binding PF00550.20 EGD97620.1 - 3.2e-06 27.3 0.0 8.8e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD97620.1 - 0.00051 20.9 0.2 0.0013 19.6 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Transp_cyt_pur PF02133.10 EGD97621.1 - 5.3e-80 269.1 32.0 2.4e-79 266.9 22.2 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin GFO_IDH_MocA PF01408.17 EGD97622.1 - 2.5e-16 60.2 0.1 4e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGD97622.1 - 0.00016 21.4 0.0 0.0014 18.3 0.0 2.4 2 1 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain ADSL_C PF10397.4 EGD97622.1 - 0.00092 19.1 0.2 0.42 10.6 0.0 2.3 2 0 0 2 2 2 2 Adenylosuccinate lyase C-terminus NAD_binding_3 PF03447.11 EGD97622.1 - 0.013 15.8 0.3 0.032 14.6 0.2 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 EGD97622.1 - 0.07 13.3 0.1 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Methyltransf_2 PF00891.13 EGD97623.1 - 1.5e-33 115.9 0.0 2e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGD97623.1 - 0.002 18.6 0.0 0.0082 16.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Rrf2 PF02082.15 EGD97623.1 - 0.019 15.1 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator DUF4131 PF13567.1 EGD97624.1 - 1 8.7 0.0 1 8.7 0.0 3.6 3 2 1 4 4 4 0 Domain of unknown function (DUF4131) GDPD PF03009.12 EGD97626.1 - 1.5e-64 217.9 0.0 4.1e-64 216.5 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EGD97626.1 - 4e-31 107.2 1.4 7.8e-13 48.5 0.5 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD97626.1 - 1.6e-27 95.3 1.1 8.6e-09 35.6 0.1 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EGD97626.1 - 5.9e-26 88.9 2.9 8.6e-07 28.4 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat SPX PF03105.14 EGD97626.1 - 6.8e-26 91.6 10.1 4.8e-15 56.0 2.3 3.8 3 1 0 3 3 3 2 SPX domain Ank_5 PF13857.1 EGD97626.1 - 5.7e-19 67.7 0.3 8.8e-07 28.9 0.0 4.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD97626.1 - 4.9e-15 54.1 1.8 0.003 17.6 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Plectin PF00681.15 EGD97626.1 - 0.024 14.1 0.1 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 Plectin repeat TAT_signal PF10518.4 EGD97626.1 - 0.13 12.3 0.2 2.7 8.2 0.1 2.5 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence PRMT5 PF05185.11 EGD97627.1 - 1.1e-163 545.2 0.0 1.4e-163 544.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 EGD97628.1 - 4.6e-25 87.6 0.0 1.1e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGD97628.1 - 8.8e-24 83.4 0.1 2.6e-23 81.9 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGD97628.1 - 2.6e-10 40.0 0.0 5.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD97628.1 - 8.3e-07 28.6 0.1 1.6e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGD97628.1 - 1.7e-05 24.9 0.2 6.9e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EGD97628.1 - 0.00036 20.0 0.1 0.0009 18.7 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EGD97628.1 - 0.0018 18.1 0.0 0.69 9.7 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EGD97628.1 - 0.002 17.8 0.1 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 EGD97628.1 - 0.021 13.7 0.0 0.041 12.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EGD97628.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGD97628.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain EF-hand_6 PF13405.1 EGD97630.1 - 5.9e-09 35.0 0.2 0.00052 19.6 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EGD97630.1 - 0.00085 19.4 1.0 0.0019 18.3 0.1 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGD97630.1 - 0.024 13.9 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 EF hand Met_10 PF02475.11 EGD97631.1 - 8e-05 22.3 0.1 0.00037 20.1 0.0 2.0 2 1 0 2 2 2 1 Met-10+ like-protein HpaP PF09483.5 EGD97632.1 - 0.027 14.4 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) MFS_1 PF07690.11 EGD97634.1 - 1.9e-22 79.4 44.1 3.7e-18 65.3 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 EGD97635.1 - 8.5e-09 34.9 1.6 9.1e-05 22.2 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EGD97635.1 - 0.00077 18.3 0.0 0.081 11.7 0.0 2.4 2 0 0 2 2 2 2 Coatomer WD associated region Apc4_WD40 PF12894.2 EGD97635.1 - 0.0038 16.6 0.1 4.5 6.8 0.0 3.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.17 EGD97635.1 - 0.0067 15.8 0.2 1.3 8.3 0.1 3.2 3 1 0 3 3 3 1 CNH domain CPSF_A PF03178.10 EGD97635.1 - 0.024 13.7 0.1 0.37 9.8 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region Kelch_4 PF13418.1 EGD97636.1 - 7.5e-14 51.2 24.1 5.7e-06 26.0 0.0 6.1 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EGD97636.1 - 5.9e-07 29.4 12.3 0.004 17.2 0.0 5.5 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EGD97636.1 - 0.0041 17.0 7.1 0.37 10.7 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EGD97636.1 - 0.04 13.7 10.5 2 8.2 0.6 4.7 5 0 0 5 5 5 0 Kelch motif LCM PF04072.9 EGD97636.1 - 0.089 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase Kelch_6 PF13964.1 EGD97636.1 - 2.2 8.5 10.3 31 4.9 0.0 4.5 4 1 0 4 4 4 0 Kelch motif DSPc PF00782.15 EGD97638.1 - 3.1e-28 98.0 0.0 2.1e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD97638.1 - 0.00011 21.5 0.0 0.00098 18.5 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DNA_mis_repair PF01119.14 EGD97640.1 - 2e-32 111.1 0.1 6e-32 109.5 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EGD97640.1 - 1.6e-14 53.7 0.0 3.2e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGD97640.1 - 1.9e-10 40.4 0.0 5.3e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OapA_N PF08525.6 EGD97641.1 - 0.3 10.8 1.6 0.65 9.8 1.1 1.6 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif PC_rep PF01851.17 EGD97642.1 - 8.8e-19 66.6 19.1 7.9e-05 22.6 0.1 8.3 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EGD97642.1 - 0.00018 21.7 0.6 1.1 9.5 0.0 4.1 3 1 0 3 3 3 2 HEAT repeats DUF106 PF01956.11 EGD97642.1 - 0.059 12.8 0.1 13 5.2 0.0 2.4 2 0 0 2 2 2 0 Integral membrane protein DUF106 TPR_5 PF12688.2 EGD97642.1 - 0.086 12.8 0.8 4.5 7.3 0.0 3.2 3 0 0 3 3 3 0 Tetratrico peptide repeat BTK PF00779.14 EGD97643.1 - 0.034 13.7 2.0 0.082 12.5 1.4 1.7 1 0 0 1 1 1 0 BTK motif Cyclin PF08613.6 EGD97645.1 - 6.3e-16 59.1 0.7 1.1e-15 58.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EGD97645.1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyr_redox_2 PF07992.9 EGD97648.1 - 4.7e-25 88.6 0.1 2.6e-14 53.6 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD97648.1 - 5.2e-13 49.1 0.0 2.7e-11 43.7 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD97648.1 - 0.00024 21.2 1.3 0.49 10.4 0.4 3.5 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase CAP_N PF01213.14 EGD97648.1 - 1.3 8.2 5.0 1.1 8.4 1.5 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF4381 PF14316.1 EGD97649.1 - 0.051 13.6 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1049 PF06305.6 EGD97649.1 - 0.06 12.8 0.6 0.1 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) HemY_N PF07219.8 EGD97649.1 - 0.18 11.3 0.4 0.27 10.8 0.3 1.2 1 0 0 1 1 1 0 HemY protein N-terminus ASFV_J13L PF05568.6 EGD97649.1 - 0.65 9.5 3.1 9.7 5.6 0.5 2.4 2 0 0 2 2 2 0 African swine fever virus J13L protein SKG6 PF08693.5 EGD97649.1 - 1.2 8.5 6.0 2 7.8 4.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Acetyltransf_1 PF00583.19 EGD97650.1 - 1e-08 35.0 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD97650.1 - 1.3e-08 34.8 0.1 2.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD97650.1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD97650.1 - 1.8e-05 24.4 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EGD97650.1 - 1.8e-05 24.5 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD97650.1 - 0.0021 17.8 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Arrestin_C PF02752.17 EGD97651.1 - 9e-18 64.6 0.0 7.7e-17 61.6 0.0 2.6 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGD97651.1 - 7.4e-09 35.5 0.1 7.6e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain RRM_1 PF00076.17 EGD97653.1 - 1.1e-48 162.7 0.0 1.2e-20 72.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD97653.1 - 3.3e-35 119.8 0.1 1.4e-13 50.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD97653.1 - 2e-19 69.1 0.0 7.8e-10 38.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cas_Cas2CT1978 PF09707.5 EGD97653.1 - 0.0046 16.8 0.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM_2 PF14605.1 EGD97653.1 - 0.0059 16.3 0.1 9.5 6.0 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EGD97653.1 - 0.0093 15.6 0.0 6.7 6.5 0.0 3.1 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PIG-Y PF15159.1 EGD97654.1 - 8.6 6.6 8.8 32 4.8 6.1 2.0 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y GATase_4 PF13230.1 EGD97655.1 - 2.2e-16 59.3 0.0 2.3e-14 52.7 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGD97655.1 - 1e-08 35.2 0.0 2.6e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EGD97655.1 - 3e-06 26.2 0.1 0.00022 20.0 0.3 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Kazal_2 PF07648.10 EGD97656.1 - 6.2e-09 35.6 2.3 9.4e-09 35.0 1.6 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EGD97656.1 - 1.2e-06 28.3 2.2 1.8e-06 27.8 1.5 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain GDC-P PF02347.11 EGD97656.1 - 0.13 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Dynamin_N PF00350.18 EGD97657.1 - 3.8e-25 88.6 1.8 7e-17 61.7 0.1 2.8 2 1 1 3 3 3 2 Dynamin family Dynamin_M PF01031.15 EGD97657.1 - 3.7e-10 39.0 0.3 7.4e-08 31.5 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region Miro PF08477.8 EGD97657.1 - 0.004 17.6 0.0 0.0089 16.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EGD97657.1 - 0.021 14.8 0.5 0.42 10.5 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain Ribosomal_S6 PF01250.12 EGD97658.1 - 1.2e-08 34.6 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 GCV_H PF01597.14 EGD97659.1 - 3.6e-39 133.2 0.4 3.9e-39 133.0 0.2 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EGD97659.1 - 0.0011 18.6 0.2 0.0016 18.1 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.17 EGD97659.1 - 0.0061 16.1 2.6 0.0065 16.0 0.6 2.0 2 1 0 2 2 2 1 Biotin-requiring enzyme zf-rbx1 PF12678.2 EGD97660.1 - 2.3e-09 37.1 1.5 4.3e-09 36.3 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGD97660.1 - 6.2e-09 35.5 10.2 1.2e-07 31.4 7.0 2.3 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGD97660.1 - 4.8e-07 29.3 3.5 1.5e-06 27.7 2.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGD97660.1 - 3.4e-06 26.6 6.0 1.5e-05 24.5 4.1 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD97660.1 - 4.6e-06 26.1 2.2 7.8e-06 25.4 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD97660.1 - 1.2e-05 25.1 3.1 1.2e-05 25.1 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.3 EGD97660.1 - 0.014 13.1 0.7 0.021 12.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-Apc11 PF12861.2 EGD97660.1 - 0.021 14.6 3.7 0.047 13.5 2.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EGD97660.1 - 1.5 8.8 5.8 4.2 7.4 2.4 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 EGD97660.1 - 5 7.2 6.6 0.73 9.9 1.5 1.9 2 0 0 2 2 2 0 RING-variant domain zf-RING_UBOX PF13445.1 EGD97660.1 - 6.6 6.5 9.1 0.15 11.8 0.8 2.4 2 1 1 3 3 3 0 RING-type zinc-finger Cation_efflux PF01545.16 EGD97661.1 - 2e-35 122.2 7.7 2.6e-35 121.8 5.3 1.1 1 0 0 1 1 1 1 Cation efflux family COMPASS-Shg1 PF05205.7 EGD97664.1 - 2.3e-11 43.9 1.4 9e-10 38.8 0.0 3.1 3 1 1 4 4 4 2 COMPASS (Complex proteins associated with Set1p) component shg1 Ribosomal_L27 PF01016.14 EGD97664.1 - 0.036 13.8 0.3 0.1 12.4 0.2 1.7 1 0 0 1 1 1 0 Ribosomal L27 protein IF4E PF01652.13 EGD97665.1 - 2.9e-33 114.7 0.3 3.6e-33 114.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4598 PF15370.1 EGD97666.1 - 1.5e-24 86.4 3.9 1.5e-24 86.4 2.7 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) CENP-B_dimeris PF09026.5 EGD97666.1 - 1.7 8.9 11.3 0.062 13.5 1.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GDA1_CD39 PF01150.12 EGD97667.1 - 1.4e-97 327.0 0.0 1.8e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family IF3_C PF00707.17 EGD97668.1 - 2.5e-14 52.7 1.4 4e-14 52.1 0.9 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 EGD97668.1 - 1e-07 31.7 1.7 1.3e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.1 EGD97668.1 - 7.9e-07 28.6 2.0 5.5e-06 25.8 1.4 2.0 1 1 0 1 1 1 1 Mitochondrial translation initiation factor FACT-Spt16_Nlob PF14826.1 EGD97668.1 - 0.028 13.9 0.2 0.051 13.0 0.1 1.4 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain GTP_EFTU PF00009.22 EGD97669.1 - 1.2e-60 204.2 0.0 1.6e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGD97669.1 - 3.1e-22 78.5 0.0 7.8e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGD97669.1 - 7.7e-18 64.3 1.9 1.9e-17 63.1 1.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGD97669.1 - 1.8e-05 24.6 0.0 3.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD97669.1 - 0.00044 20.7 0.0 0.0008 19.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EGD97669.1 - 0.00072 19.1 0.2 0.0018 17.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 EGD97669.1 - 0.03 13.8 0.1 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Hepatitis_core PF00906.15 EGD97669.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Hepatitis core antigen cobW PF02492.14 EGD97669.1 - 0.1 12.0 0.3 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Radical_SAM PF04055.16 EGD97670.1 - 4.4e-15 56.2 0.1 1.1e-14 54.8 0.1 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EGD97670.1 - 2.8e-08 33.7 0.1 6.3e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EGD97670.1 - 7.6e-08 32.5 0.1 1.5e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain bZIP_1 PF00170.16 EGD97673.1 - 0.00018 21.3 11.7 0.00037 20.3 8.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF4072 PF13284.1 EGD97673.1 - 0.036 14.2 2.2 0.55 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) PI3K_1B_p101 PF10486.4 EGD97673.1 - 0.099 10.1 1.0 0.13 9.8 0.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DivIC PF04977.10 EGD97673.1 - 0.1 12.0 1.0 0.24 10.9 0.7 1.6 1 0 0 1 1 1 0 Septum formation initiator APG6 PF04111.7 EGD97673.1 - 0.68 8.9 3.7 0.9 8.5 2.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 MFS_1 PF07690.11 EGD97674.1 - 3.5e-37 127.9 51.7 3.5e-37 127.9 35.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD97674.1 - 1.8e-14 52.9 22.0 2.9e-14 52.2 15.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 EGD97675.1 - 1.1e-05 24.5 0.0 6.8e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD97675.1 - 5.6e-05 22.9 8.6 0.00013 21.7 6.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EGD97677.1 - 1.3e-22 80.0 44.6 1.5e-21 76.5 29.9 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_hub_GP28 PF11110.3 EGD97677.1 - 0.16 11.6 0.7 0.28 10.8 0.5 1.4 1 0 0 1 1 1 0 Baseplate hub distal subunit RHD3 PF05879.7 EGD97678.1 - 4.7e-300 996.8 0.0 2e-185 617.9 1.2 2.0 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EGD97678.1 - 8.1e-08 31.6 0.1 1.5e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EGD97678.1 - 2.8e-06 27.2 0.1 5.3e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EGD97678.1 - 7.8e-05 22.6 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EGD97678.1 - 0.00016 21.7 0.1 0.00062 19.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EGD97678.1 - 0.00056 20.3 0.2 0.0017 18.8 0.1 1.9 2 0 0 2 2 2 1 Miro-like protein Septin PF00735.13 EGD97678.1 - 0.00058 18.9 0.1 0.0012 17.8 0.1 1.5 1 0 0 1 1 1 1 Septin Thr_synth_N PF14821.1 EGD97678.1 - 0.11 12.5 0.0 0.41 10.7 0.0 1.9 1 0 0 1 1 1 0 Threonine synthase N terminus DIM1 PF02966.11 EGD97679.1 - 6.2e-69 229.6 0.1 7.1e-69 229.4 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EGD97679.1 - 0.015 15.3 0.4 0.03 14.4 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.15 EGD97679.1 - 0.018 14.7 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin 4HBT_2 PF13279.1 EGD97680.1 - 3e-10 40.5 0.0 4.6e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily HIG_1_N PF04588.8 EGD97681.1 - 1.1e-06 28.2 0.3 1.1e-06 28.2 0.2 2.0 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Med26 PF08711.6 EGD97682.1 - 2.7e-11 42.7 0.1 5.1e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Tom5 PF10642.4 EGD97683.1 - 1e-16 60.2 0.1 1.1e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.1 EGD97684.1 - 4.6e-46 155.9 3.7 4.9e-46 155.8 0.4 2.4 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EGD97684.1 - 6.2e-08 32.8 39.8 6.2e-08 32.8 27.6 3.0 1 1 2 3 3 3 2 Nucleoporin FG repeat region Fib_alpha PF08702.5 EGD97684.1 - 0.034 14.2 0.7 0.034 14.2 0.5 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Uds1 PF15456.1 EGD97684.1 - 5.5 7.0 11.0 25 4.8 1.4 3.1 1 1 1 2 2 2 0 Up-regulated During Septation AAA PF00004.24 EGD97685.1 - 8.9e-15 55.0 0.0 2.6e-14 53.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGD97685.1 - 6e-11 42.6 0.0 6.3e-10 39.3 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGD97685.1 - 2.4e-08 34.1 0.0 1.6e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGD97685.1 - 1.1e-05 25.1 1.3 4e-05 23.2 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EGD97685.1 - 0.00059 20.6 0.0 0.0063 17.3 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EGD97685.1 - 0.00099 19.1 0.0 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGD97685.1 - 0.0017 17.9 0.0 0.0037 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EGD97685.1 - 0.0033 17.1 0.0 0.0097 15.5 0.0 1.8 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EGD97685.1 - 0.0064 15.5 0.0 0.04 12.9 0.0 2.1 2 0 0 2 2 2 1 KAP family P-loop domain Arch_ATPase PF01637.13 EGD97685.1 - 0.011 15.4 0.0 0.084 12.5 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 EGD97685.1 - 0.015 15.4 0.0 0.081 13.1 0.0 2.3 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.1 EGD97685.1 - 0.018 14.9 0.0 0.25 11.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 EGD97685.1 - 0.023 13.7 0.0 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Pol_alpha_B_N PF08418.5 EGD97685.1 - 0.029 13.9 5.7 0.045 13.2 0.6 2.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal BAH PF01426.13 EGD97685.1 - 0.039 13.6 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 BAH domain PIF1 PF05970.9 EGD97685.1 - 0.061 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Zot PF05707.7 EGD97685.1 - 0.081 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_32 PF13654.1 EGD97685.1 - 0.1 11.2 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGD97685.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 NTPase WD40 PF00400.27 EGD97686.1 - 7.2e-51 168.3 13.8 2.8e-10 39.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGD97686.1 - 0.0021 16.2 5.0 3.3 5.7 0.0 4.4 1 1 4 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EGD97686.1 - 0.054 12.9 0.6 8.9 5.6 0.0 2.6 2 1 0 2 2 2 0 PQQ-like domain Ank_2 PF12796.2 EGD97687.1 - 2.4e-49 165.5 1.2 8e-19 67.7 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD97687.1 - 2e-33 113.6 2.3 1.5e-09 37.7 0.0 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EGD97687.1 - 1.3e-31 106.7 0.4 8.5e-05 22.1 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EGD97687.1 - 3.7e-31 106.9 1.9 5.8e-09 36.2 0.0 4.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD97687.1 - 1.7e-27 92.7 0.4 0.0024 17.9 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Shal-type PF11601.3 EGD97687.1 - 0.038 13.4 0.3 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels TMF_TATA_bd PF12325.3 EGD97688.1 - 5.1e-42 142.4 13.2 5.1e-42 142.4 9.1 6.6 3 1 3 6 6 6 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EGD97688.1 - 2.4e-22 78.4 19.1 2.4e-22 78.4 13.2 8.6 5 3 2 7 7 7 1 TATA element modulatory factor 1 DNA binding V-ATPase_H_N PF03224.9 EGD97690.1 - 1.2e-79 267.6 0.0 1.8e-79 267.0 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EGD97690.1 - 2.3e-39 133.9 0.1 8.3e-39 132.1 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H HR1 PF02185.11 EGD97691.1 - 0.012 15.2 4.4 0.012 15.2 3.0 6.7 6 2 1 7 7 7 0 Hr1 repeat APH PF01636.18 EGD97692.1 - 7.6e-09 35.6 1.5 9e-09 35.4 0.3 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family HNH_2 PF13391.1 EGD97693.1 - 4.8e-11 42.2 0.1 1.4e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease Rnk_N PF14760.1 EGD97693.1 - 0.086 12.9 0.6 0.19 11.8 0.1 1.8 2 0 0 2 2 2 0 Rnk N-terminus Phage_int_SAM_1 PF02899.12 EGD97695.1 - 0.054 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain HSDR_N PF04313.9 EGD97696.1 - 0.037 13.7 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) F-box PF00646.28 EGD97697.1 - 0.0036 16.9 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD97697.1 - 0.079 12.6 0.1 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like His_Phos_1 PF00300.17 EGD97699.1 - 9.1e-08 32.3 0.3 1.4e-05 25.2 0.1 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Peptidase_M35 PF02102.10 EGD97700.1 - 1e-89 300.7 12.5 1.1e-51 175.5 4.4 2.0 1 1 1 2 2 2 2 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGD97700.1 - 1.7e-05 25.3 0.1 3.2e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EGD97700.1 - 0.0047 16.3 1.1 0.016 14.6 0.7 1.9 1 1 0 1 1 1 1 Putative peptidase family UPF0160 PF03690.8 EGD97703.1 - 4.4e-115 384.4 0.0 5e-115 384.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) 5_nucleotid_C PF02872.13 EGD97705.1 - 1.9e-35 122.1 0.0 3.2e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EGD97705.1 - 3e-09 36.5 0.0 4.8e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD97705.1 - 0.01 15.7 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_C1_2 PF03051.10 EGD97707.1 - 3.8e-135 450.7 0.0 4.8e-135 450.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EGD97707.1 - 1.4e-05 25.1 0.0 3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Papain family cysteine protease Kinesin PF00225.18 EGD97708.1 - 4.4e-112 374.0 0.4 4.4e-112 374.0 0.3 1.9 2 0 0 2 2 2 1 Kinesin motor domain Thiolase_N PF00108.18 EGD97709.1 - 3.3e-96 321.3 1.3 4.3e-96 320.9 0.9 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGD97709.1 - 2.3e-37 127.1 0.7 2.3e-37 127.1 0.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGD97709.1 - 0.00022 20.7 1.0 0.0004 19.9 0.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EGD97709.1 - 0.093 12.4 3.5 3 7.5 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Asp_protease_2 PF13650.1 EGD97710.1 - 0.015 15.8 0.2 0.029 14.8 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Helicase_C PF00271.26 EGD97711.1 - 8.4e-11 41.5 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EGD97711.1 - 0.019 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain UQ_con PF00179.21 EGD97713.1 - 1.2e-51 173.7 0.0 1.4e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD97713.1 - 3.3e-06 26.8 0.0 3.7e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGD97713.1 - 0.061 13.2 0.1 0.093 12.6 0.0 1.5 1 1 0 1 1 1 0 RWD domain Cation_efflux PF01545.16 EGD97714.1 - 8.6e-54 182.5 13.8 8.6e-54 182.5 9.5 3.4 3 0 0 3 3 3 1 Cation efflux family Neur_chan_memb PF02932.11 EGD97714.1 - 0.98 9.2 4.7 1.1 9.0 0.3 2.9 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Glyco_trans_1_4 PF13692.1 EGD97715.1 - 2.8e-23 82.5 0.2 1.6e-22 80.1 0.0 2.2 3 1 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGD97715.1 - 8e-11 42.3 1.1 1.2e-10 41.7 0.8 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain TFIIIC_delta PF12657.2 EGD97716.1 - 3.7e-43 147.2 0.2 7.4e-43 146.2 0.1 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EGD97716.1 - 2e-25 88.5 2.0 4e-25 87.5 1.4 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Mito_carr PF00153.22 EGD97717.1 - 2.1e-61 203.6 6.3 3.3e-21 74.7 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LtrA PF06772.6 EGD97718.1 - 3.1e-16 59.2 30.7 7.2e-16 58.0 16.1 3.0 2 1 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) DUF1772 PF08592.6 EGD97718.1 - 0.021 14.5 0.5 0.021 14.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2976 PF11190.3 EGD97718.1 - 0.022 14.2 0.7 0.022 14.2 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) HNH_2 PF13391.1 EGD97719.1 - 1.3e-12 47.2 0.2 3.4e-12 45.9 0.1 1.8 2 0 0 2 2 2 1 HNH endonuclease Ribosomal_L16 PF00252.13 EGD97720.1 - 8.7e-10 38.4 0.0 1.2e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e AA_permease PF00324.16 EGD97721.1 - 1.1e-60 205.3 27.6 7.7e-60 202.5 19.1 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD97721.1 - 4.4e-22 78.2 23.1 7.7e-22 77.4 15.8 1.5 1 1 1 2 2 2 1 Amino acid permease DUF2207 PF09972.4 EGD97721.1 - 0.82 8.1 10.5 0.053 12.1 1.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) UQ_con PF00179.21 EGD97723.1 - 8.8e-45 151.5 0.0 9.8e-45 151.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD97723.1 - 0.079 12.7 0.2 0.14 11.9 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EGD97723.1 - 0.16 11.8 1.4 0.38 10.6 1.0 1.8 1 1 0 1 1 1 0 RWD domain CFEM PF05730.6 EGD97724.1 - 1.6e-12 47.0 5.5 2.3e-12 46.5 3.8 1.2 1 0 0 1 1 1 1 CFEM domain APH PF01636.18 EGD97726.1 - 6.2e-16 58.8 0.0 1.4e-15 57.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGD97726.1 - 0.0017 17.0 0.0 0.04 12.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Amidoligase_2 PF12224.3 EGD97727.1 - 9.6e-16 58.1 0.0 4.1e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 Putative amidoligase enzyme MFS_1 PF07690.11 EGD97729.1 - 9.7e-12 44.2 40.2 1.4e-11 43.7 27.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGD97729.1 - 5.3e-08 32.5 6.0 5.3e-08 32.5 4.2 2.9 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Sas10_Utp3 PF04000.10 EGD97730.1 - 3.3e-18 65.6 1.7 9.9e-18 64.1 1.2 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Daxx PF03344.10 EGD97730.1 - 0.0038 15.8 16.2 0.0046 15.5 11.2 1.1 1 0 0 1 1 1 1 Daxx Family Ebola_NP PF05505.7 EGD97730.1 - 0.013 13.5 8.0 0.016 13.3 5.5 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein DUF913 PF06025.7 EGD97730.1 - 0.26 9.9 4.5 0.53 8.9 3.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CENP-B_dimeris PF09026.5 EGD97730.1 - 1.1 9.5 12.0 3.1 8.1 8.3 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EGD97730.1 - 1.9 7.6 11.1 3.4 6.8 7.7 1.4 1 0 0 1 1 1 0 NOA36 protein Hid1 PF12722.2 EGD97730.1 - 2.2 5.8 7.3 2.9 5.4 5.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleoplasmin PF03066.10 EGD97730.1 - 3.5 7.1 9.6 9.1 5.7 6.7 1.7 1 0 0 1 1 1 0 Nucleoplasmin DUF2151 PF10221.4 EGD97730.1 - 8.8 4.3 10.3 12 3.9 7.1 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator PrpR_N PF06506.6 EGD97731.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Propionate catabolism activator Pyr_redox_3 PF13738.1 EGD97732.1 - 4.7e-18 65.9 0.0 1.4e-17 64.4 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGD97732.1 - 1.3e-13 50.0 0.0 7.8e-13 47.4 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EGD97732.1 - 6.2e-13 49.0 0.0 4.9e-11 42.8 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD97732.1 - 3e-09 36.2 0.0 1e-06 27.9 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGD97732.1 - 2.2e-07 30.8 2.1 5.9e-06 26.2 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGD97732.1 - 5.5e-07 29.8 3.1 0.014 15.8 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD97732.1 - 8e-05 21.7 0.2 0.00044 19.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGD97732.1 - 0.00041 20.1 1.8 0.025 14.3 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EGD97732.1 - 0.0016 18.0 0.4 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EGD97732.1 - 0.0019 18.4 0.2 0.03 14.5 0.1 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EGD97732.1 - 0.002 18.2 0.1 0.32 11.1 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EGD97732.1 - 0.0032 17.1 0.3 0.0071 16.0 0.2 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EGD97732.1 - 0.03 13.1 0.2 0.03 13.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EGD97732.1 - 0.26 9.7 1.5 0.88 7.9 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.17 EGD97732.1 - 7.4 5.3 6.2 0.83 8.4 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NmrA PF05368.8 EGD97733.1 - 7.6e-07 28.6 0.0 9.4e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Med3 PF11593.3 EGD97735.1 - 2.5 7.2 5.8 3.3 6.8 4.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.11 EGD97737.1 - 1.8e-34 119.0 51.2 1.8e-34 119.0 35.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD97737.1 - 1.4e-20 73.0 13.7 1.8e-20 72.6 9.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGD97737.1 - 2.4e-12 46.1 9.9 2.4e-12 46.1 6.8 2.9 3 1 0 4 4 4 1 Sugar (and other) transporter DUF4407 PF14362.1 EGD97737.1 - 0.22 10.4 0.6 0.6 9.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.20 EGD97738.1 - 1.2e-08 34.4 0.0 2.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EGD97738.1 - 0.0097 15.2 0.0 0.025 13.9 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EGD97738.1 - 0.012 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase EMP70 PF02990.11 EGD97739.1 - 2.9e-181 603.4 2.3 2.9e-181 603.4 1.6 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 APH PF01636.18 EGD97740.1 - 4.6e-11 42.9 0.0 9.9e-11 41.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGD97740.1 - 0.00054 19.2 0.0 0.00095 18.3 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EGD97740.1 - 0.0088 14.7 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EGD97740.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EF-hand_7 PF13499.1 EGD97741.1 - 1e-29 102.4 4.8 2.8e-13 49.7 0.2 3.1 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 EGD97741.1 - 2.1e-26 89.1 9.6 3.4e-08 32.2 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EGD97741.1 - 8.5e-25 84.3 2.0 2.7e-06 26.7 0.0 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EGD97741.1 - 4.5e-18 63.6 15.4 1.3e-05 24.2 0.0 4.8 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.1 EGD97741.1 - 5.4e-15 54.7 15.0 3.2e-06 26.6 1.0 4.3 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EGD97741.1 - 3.9e-09 36.1 4.7 0.00093 18.9 0.1 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EGD97741.1 - 0.00026 20.8 0.3 0.36 10.7 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain EF-hand_10 PF14788.1 EGD97741.1 - 0.0033 17.0 1.0 1.5 8.5 0.0 3.9 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 EGD97741.1 - 0.0064 16.4 0.5 0.45 10.5 0.1 3.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.6 EGD97741.1 - 0.014 14.1 0.5 1 7.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Mad3_BUB1_II PF08171.6 EGD97741.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 EF-hand_2 PF09068.6 EGD97741.1 - 0.087 12.8 0.0 14 5.7 0.0 3.0 3 1 0 3 3 3 0 EF hand Med4 PF10018.4 EGD97742.1 - 2.3e-32 111.9 0.4 4.8e-32 110.8 0.2 1.6 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Ada3 PF10198.4 EGD97742.1 - 0.26 11.0 1.7 0.74 9.5 0.3 2.4 3 0 0 3 3 3 0 Histone acetyltransferases subunit 3 MFS_1 PF07690.11 EGD97743.1 - 7.2e-28 97.3 36.5 1.2e-27 96.5 24.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD97743.1 - 0.00089 17.5 2.9 0.0012 17.1 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EGF_2 PF07974.8 EGD97744.1 - 1.8 8.8 10.2 2.8 8.1 7.1 1.3 1 0 0 1 1 1 0 EGF-like domain RabGAP-TBC PF00566.13 EGD97745.1 - 9.2e-48 162.5 2.2 1e-47 162.3 0.0 2.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF1664 PF07889.7 EGD97745.1 - 1.1 9.0 7.1 0.16 11.7 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2570 PF10828.3 EGD97745.1 - 1.8 8.1 14.5 0.53 9.9 2.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) Acyl-CoA_dh_1 PF00441.19 EGD97746.1 - 4.5e-30 104.7 2.0 4.5e-30 104.7 1.4 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGD97746.1 - 7.8e-23 81.2 0.2 1.7e-22 80.1 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGD97746.1 - 1.5e-15 57.6 3.6 1.5e-15 57.6 0.7 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGD97746.1 - 1.9e-11 43.2 0.0 4.1e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Reticulon PF02453.12 EGD97747.1 - 9.4e-37 126.2 4.9 1.4e-36 125.6 3.4 1.2 1 0 0 1 1 1 1 Reticulon Pex24p PF06398.6 EGD97747.1 - 0.0044 15.8 4.9 0.0056 15.5 2.6 1.5 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin Phasin_2 PF09361.5 EGD97747.1 - 0.32 11.0 3.4 0.26 11.3 0.4 2.1 2 0 0 2 2 2 0 Phasin protein KAR9 PF08580.5 EGD97747.1 - 2.1 6.5 5.4 0.81 7.8 0.9 1.9 2 0 0 2 2 2 0 Yeast cortical protein KAR9 DNA_topoisoIV PF00521.15 EGD97749.1 - 2.1e-133 445.2 0.0 5e-133 444.0 0.0 1.7 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EGD97749.1 - 9.6e-35 119.3 3.5 2.8e-34 117.8 2.4 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EGD97749.1 - 5.4e-13 48.7 0.2 3.9e-12 46.0 0.0 2.6 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EGD97749.1 - 4.3e-11 42.5 0.0 1.2e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase INCENP_ARK-bind PF03941.10 EGD97750.1 - 1.1e-18 66.7 0.4 1.1e-18 66.7 0.2 2.1 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region PDZ_1 PF12812.2 EGD97751.1 - 1.6e-53 178.4 0.0 3.5e-34 116.5 0.0 3.3 3 0 0 3 3 3 2 PDZ-like domain PDZ_2 PF13180.1 EGD97751.1 - 1.5e-15 56.8 0.3 3.7e-06 26.7 0.0 4.2 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 EGD97751.1 - 1.2e-12 47.8 0.0 4.8e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EGD97751.1 - 4.5e-10 39.5 0.0 0.00021 21.3 0.0 3.6 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EGD97751.1 - 0.0017 18.0 0.1 0.15 11.8 0.1 3.5 4 0 0 4 4 4 1 Tricorn protease PDZ domain SSXT PF05030.7 EGD97752.1 - 2.2e-05 23.9 0.8 0.48 10.0 0.0 3.1 3 0 0 3 3 3 2 SSXT protein (N-terminal region) POX PF07526.6 EGD97752.1 - 0.72 10.0 0.1 0.72 10.0 0.0 2.3 2 1 1 3 3 3 0 Associated with HOX Tmemb_55A PF09788.4 EGD97752.1 - 3.9 6.5 7.4 0.24 10.4 1.1 1.8 2 0 0 2 2 2 0 Transmembrane protein 55A PAT1 PF09770.4 EGD97753.1 - 0.085 11.0 78.9 0.11 10.6 54.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ABC_membrane PF00664.18 EGD97754.1 - 7e-55 186.3 20.9 2.1e-41 142.1 7.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD97754.1 - 4.9e-50 169.3 0.0 2.3e-32 112.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGD97754.1 - 8.4e-11 41.5 0.3 0.00052 19.3 0.0 3.5 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD97754.1 - 2.5e-10 40.7 0.0 0.0015 18.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGD97754.1 - 6.9e-08 31.9 1.0 0.0041 16.6 0.1 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGD97754.1 - 1.4e-07 31.6 5.5 0.0039 17.1 0.0 3.4 3 1 1 4 4 3 2 AAA ATPase domain AAA_17 PF13207.1 EGD97754.1 - 4.4e-07 30.7 0.0 0.024 15.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain FAD_binding_4 PF01565.18 EGD97754.1 - 4.6e-07 29.3 1.5 1.4e-06 27.8 0.2 2.5 2 0 0 2 2 2 1 FAD binding domain DUF258 PF03193.11 EGD97754.1 - 1.5e-06 27.5 0.1 0.01 15.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EGD97754.1 - 1.9e-06 27.5 0.1 0.8 9.2 0.0 3.7 3 0 0 3 3 3 3 AAA domain AAA_22 PF13401.1 EGD97754.1 - 3.7e-06 27.1 2.2 0.087 12.9 0.0 3.8 3 1 0 3 3 3 2 AAA domain DUF87 PF01935.12 EGD97754.1 - 1.4e-05 25.0 0.0 0.0052 16.6 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_23 PF13476.1 EGD97754.1 - 0.0001 22.7 0.0 0.08 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGD97754.1 - 0.00017 21.4 0.0 0.94 9.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGD97754.1 - 0.00021 21.6 0.0 0.32 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EGD97754.1 - 0.0004 19.0 0.3 0.0004 19.0 0.2 1.8 2 0 0 2 2 1 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 EGD97754.1 - 0.00044 19.3 0.2 0.38 9.8 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_5 PF07728.9 EGD97754.1 - 0.00045 19.9 0.0 0.4 10.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EGD97754.1 - 0.00064 19.9 1.8 3.9 7.6 0.6 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGD97754.1 - 0.00096 18.6 1.9 1.2 8.5 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 EGD97754.1 - 0.005 16.3 1.6 3.9 6.8 0.1 3.5 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 EGD97754.1 - 0.026 14.4 0.0 5.3 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 EGD97754.1 - 0.028 14.1 0.2 8.6 6.0 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EGD97754.1 - 0.049 13.2 0.5 0.67 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 EGD97754.1 - 0.064 12.8 0.1 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 EGD97754.1 - 0.069 11.8 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EGD97754.1 - 0.085 13.0 0.1 3.3 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EGD97754.1 - 0.091 12.7 0.2 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EGD97754.1 - 0.1 12.5 1.8 4.7 7.2 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.17 EGD97754.1 - 0.19 10.5 0.1 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 EGD97754.1 - 0.28 10.1 0.0 1.1 8.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 EGD97755.1 - 2.5e-05 23.5 0.0 4.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain AAA_35 PF14516.1 EGD97755.1 - 0.13 10.8 0.0 0.23 10.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain p450 PF00067.17 EGD97757.1 - 1.6e-30 106.0 0.0 1.8e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EGD97758.1 - 1.1e-17 63.8 0.8 1.7e-17 63.1 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD97758.1 - 5.8e-06 26.1 10.2 1.3e-05 24.9 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EGD97758.1 - 1.9 8.7 10.0 5.2 7.3 7.0 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region TPR_11 PF13414.1 EGD97759.1 - 2.4e-10 39.8 5.9 1.1e-09 37.8 0.2 2.8 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EGD97759.1 - 7.3e-07 28.5 3.4 0.1 12.2 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF3808 PF10300.4 EGD97759.1 - 0.00018 20.2 0.3 0.00025 19.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 EGD97759.1 - 0.0014 18.4 4.5 0.2 11.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD97759.1 - 0.027 14.6 2.0 0.11 12.6 0.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Syntaxin PF00804.20 EGD97760.1 - 0.061 13.4 4.1 0.09 12.9 2.4 1.6 1 1 0 1 1 1 0 Syntaxin peroxidase PF00141.18 EGD97761.1 - 8.9e-48 162.7 0.0 1.3e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase HrcA PF01628.16 EGD97762.1 - 0.29 10.6 0.0 0.49 9.9 0.0 1.3 1 0 0 1 1 1 0 HrcA protein C terminal domain COesterase PF00135.23 EGD97763.1 - 6.6e-68 229.7 0.0 9.5e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD97763.1 - 7.8e-05 22.3 0.0 0.00034 20.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 EGD97764.1 - 4.1e-06 25.6 0.5 7.1e-06 24.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyridoxal_deC PF00282.14 EGD97765.1 - 1.8e-76 257.0 0.0 2.4e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGD97765.1 - 2.2e-05 23.3 0.0 3.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 EGD97765.1 - 0.043 12.3 0.0 0.062 11.8 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Peptidase_S8 PF00082.17 EGD97766.1 - 1.5e-42 145.6 2.5 1.8e-42 145.4 1.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD97766.1 - 9.9e-11 42.0 0.0 2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3043 PF11241.3 EGD97768.1 - 0.035 13.6 12.4 0.073 12.6 8.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) FancD2 PF14631.1 EGD97768.1 - 6.1 3.7 7.7 9.4 3.1 5.4 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Rsm1 PF08600.5 EGD97770.1 - 0.76 9.6 4.9 2.1 8.2 3.4 1.7 1 0 0 1 1 1 0 Rsm1-like BAF1_ABF1 PF04684.8 EGD97770.1 - 0.89 8.3 31.2 0.019 13.8 16.5 1.8 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor MgsA_C PF12002.3 EGD97770.1 - 2.5 7.7 6.7 4.5 6.9 4.6 1.3 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal SBDS_C PF09377.5 EGD97771.1 - 1.2e-36 125.1 0.0 5.6e-36 122.9 0.0 2.1 1 1 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EGD97771.1 - 2.7e-27 94.3 0.1 5.3e-27 93.4 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein NST1 PF13945.1 EGD97771.1 - 0.28 11.2 11.0 0.96 9.4 1.2 3.0 3 0 0 3 3 3 0 Salt tolerance down-regulator RAP1 PF07218.6 EGD97771.1 - 9.3 4.2 7.0 15 3.5 4.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S10 PF00450.17 EGD97772.1 - 1e-130 436.6 0.2 1.2e-130 436.3 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGD97772.1 - 0.0055 16.6 0.0 0.036 13.9 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Carbpep_Y_N PF05388.6 EGD97772.1 - 0.0072 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Ribosomal_S13 PF00416.17 EGD97773.1 - 2.2e-41 140.6 2.8 2.6e-41 140.3 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EGD97773.1 - 0.011 14.3 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EGD97773.1 - 0.067 13.2 0.3 0.3 11.1 0.0 2.1 2 1 0 2 2 2 0 Helix-hairpin-helix motif DUF1822 PF08852.6 EGD97773.1 - 0.095 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) LysM PF01476.15 EGD97775.1 - 1.2e-16 60.2 0.0 8.4e-08 31.9 0.0 2.9 3 0 0 3 3 3 2 LysM domain Cation_efflux PF01545.16 EGD97777.1 - 8.8e-39 133.2 3.3 1.7e-38 132.3 2.3 1.4 1 1 0 1 1 1 1 Cation efflux family MARVEL PF01284.18 EGD97777.1 - 0.00019 21.2 0.1 0.1 12.4 0.0 2.5 1 1 1 2 2 2 2 Membrane-associating domain Zip PF02535.17 EGD97777.1 - 0.012 14.6 8.5 0.018 14.0 5.9 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter EphA2_TM PF14575.1 EGD97777.1 - 0.098 13.0 0.3 4.1 7.8 0.0 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Metal_resist PF13801.1 EGD97777.1 - 0.27 11.2 1.1 0.54 10.2 0.4 1.8 1 1 1 2 2 2 0 Heavy-metal resistance Ion_trans PF00520.26 EGD97778.1 - 2.4e-07 30.2 15.3 2.4e-07 30.2 10.6 1.9 2 0 0 2 2 2 1 Ion transport protein zf-MYND PF01753.13 EGD97778.1 - 3.6e-06 26.7 8.1 6.6e-06 25.8 5.6 1.4 1 0 0 1 1 1 1 MYND finger DUF3357 PF11837.3 EGD97778.1 - 0.1 12.4 1.0 0.43 10.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) zf-HIT PF04438.11 EGD97778.1 - 1.5 8.5 5.5 2.5 7.8 3.8 1.4 1 0 0 1 1 1 0 HIT zinc finger Cyclin PF08613.6 EGD97780.1 - 3.4e-14 53.4 0.5 8.5e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EGD97780.1 - 0.0019 17.7 0.0 0.0042 16.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Aminotran_4 PF01063.14 EGD97781.1 - 2.1e-21 76.4 0.0 2.7e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Sugar_tr PF00083.19 EGD97782.1 - 9.4e-83 278.2 21.5 1.1e-82 278.0 14.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD97782.1 - 2.6e-14 52.7 41.5 5.8e-11 41.7 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CDC14 PF08045.6 EGD97785.1 - 1.9e-100 335.2 0.0 2.2e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Methyltransf_31 PF13847.1 EGD97786.1 - 9.8e-16 57.6 0.0 1.3e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD97786.1 - 1.2e-15 58.0 0.0 1.7e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD97786.1 - 1.9e-14 53.8 0.0 3.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD97786.1 - 1.9e-13 50.4 0.0 2.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD97786.1 - 6.7e-13 48.9 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD97786.1 - 2.7e-09 37.2 0.0 4.6e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD97786.1 - 1.3e-05 24.4 0.0 3.4e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGD97786.1 - 2.9e-05 23.5 0.0 0.00028 20.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EGD97786.1 - 4.5e-05 22.6 0.0 5.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EGD97786.1 - 0.00013 22.0 0.1 0.00031 20.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EGD97786.1 - 0.00087 18.8 0.1 0.0041 16.6 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TehB PF03848.9 EGD97786.1 - 0.00088 18.4 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 EGD97786.1 - 0.0026 16.8 0.0 0.0052 15.8 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EGD97786.1 - 0.0041 16.6 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_7 PF03492.10 EGD97786.1 - 0.044 12.5 0.0 0.077 11.7 0.0 1.4 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Methyltransf_32 PF13679.1 EGD97786.1 - 0.046 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 EGD97786.1 - 0.083 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 VBS PF08913.5 EGD97786.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.8 2 1 0 2 2 2 0 Vinculin Binding Site Methyltransf_8 PF05148.10 EGD97786.1 - 0.17 11.5 0.0 0.58 9.7 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase Pox_MCEL PF03291.11 EGD97786.1 - 0.18 10.6 0.0 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 mRNA capping enzyme DUF2731 PF10806.3 EGD97787.1 - 5.4e-06 26.6 0.1 1.8e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) Tom37 PF10568.4 EGD97787.1 - 0.0012 19.0 0.0 0.0056 16.9 0.0 2.1 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EGD97787.1 - 0.015 15.1 0.1 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 EGD97787.1 - 0.02 14.7 0.9 0.3 10.9 0.2 2.2 1 1 1 2 2 2 0 Tom37 C-terminal domain Complex1_LYR_2 PF13233.1 EGD97787.1 - 0.13 12.7 0.3 0.29 11.6 0.2 1.6 1 0 0 1 1 1 0 Complex1_LYR-like Copper-fist PF00649.13 EGD97788.1 - 4.6e-19 67.3 0.3 4.6e-19 67.3 0.2 2.2 2 0 0 2 2 2 1 Copper fist DNA binding domain SLD3 PF08639.5 EGD97788.1 - 0.68 8.4 7.1 0.96 8.0 4.9 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF543 PF04418.7 EGD97789.1 - 1.4e-25 88.9 0.0 1.6e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.4 EGD97790.1 - 1.7e-58 197.9 7.1 9.4e-58 195.4 0.0 3.1 3 0 0 3 3 3 2 Urb2/Npa2 family A_deaminase PF00962.17 EGD97791.1 - 2.2e-28 99.1 0.0 2.6e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase p450 PF00067.17 EGD97792.1 - 5.9e-77 259.1 0.0 7.2e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EGD97793.1 - 5.2e-50 165.6 11.0 1.2e-10 40.8 0.1 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EGD97793.1 - 0.00019 19.7 0.8 0.0014 16.9 0.0 2.5 3 1 0 3 3 3 1 Nucleoporin Nup120/160 zf-C2H2 PF00096.21 EGD97794.1 - 1.7e-05 24.9 8.6 0.0012 19.0 0.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD97794.1 - 8.4e-05 22.6 7.9 0.011 15.9 0.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger DUF4613 PF15390.1 EGD97794.1 - 0.072 11.2 0.2 0.083 11.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) zf-H2C2_2 PF13465.1 EGD97794.1 - 6.6 7.2 16.1 0.35 11.2 0.4 3.7 3 1 0 3 3 3 0 Zinc-finger double domain DSPc PF00782.15 EGD97795.1 - 1.7e-12 47.0 0.0 4.2e-12 45.8 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EGD97795.1 - 0.0023 16.8 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase SNF2_N PF00176.18 EGD97797.1 - 2.5e-69 233.3 0.0 5.2e-69 232.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD97797.1 - 3.2e-16 58.9 1.7 9.5e-16 57.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain End3 PF12761.2 EGD97798.1 - 2.8e-77 258.7 1.3 3.9e-77 258.3 0.9 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EGD97798.1 - 1.9e-51 172.1 0.1 3.7e-49 164.7 0.0 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EGD97798.1 - 1e-07 30.7 0.2 3.9e-07 28.8 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EGD97798.1 - 5.3e-06 25.9 0.2 2.8e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EGD97798.1 - 8.7e-06 25.1 0.1 0.00024 20.7 0.2 2.8 3 0 0 3 3 2 1 EF-hand domain EF-hand_7 PF13499.1 EGD97798.1 - 1.7e-05 24.8 0.2 0.00019 21.5 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 EGD97798.1 - 0.00078 18.6 1.0 0.0026 17.0 0.2 2.3 2 0 0 2 2 2 1 EF hand DUF4407 PF14362.1 EGD97798.1 - 0.0019 17.2 4.1 0.0029 16.6 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) NPV_P10 PF05531.7 EGD97798.1 - 0.013 15.7 0.2 0.19 11.9 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Rabaptin PF03528.10 EGD97798.1 - 0.024 14.5 6.7 0.14 12.0 4.4 2.5 2 1 0 2 2 1 0 Rabaptin Phage_GP20 PF06810.6 EGD97798.1 - 0.026 13.9 3.1 0.034 13.5 0.3 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Med9 PF07544.8 EGD97798.1 - 0.039 13.6 0.7 0.039 13.6 0.5 2.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 COG2 PF06148.6 EGD97798.1 - 0.19 11.6 3.3 1.3 8.8 0.4 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.3 EGD97798.1 - 0.19 11.5 6.0 0.45 10.3 0.6 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Laminin_I PF06008.9 EGD97798.1 - 0.2 10.9 8.4 0.9 8.7 5.8 2.1 1 1 0 1 1 1 0 Laminin Domain I Spc7 PF08317.6 EGD97798.1 - 0.54 8.8 7.2 2.4 6.7 5.1 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EGD97798.1 - 2.1 7.9 6.1 23 4.5 3.0 2.3 2 0 0 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 EGD97798.1 - 9.2 6.0 9.5 3.3 7.4 0.6 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Mit_KHE1 PF10173.4 EGD97799.1 - 9.8e-69 230.9 1.3 1.4e-68 230.4 0.9 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related MARVEL PF01284.18 EGD97800.1 - 0.0037 17.0 2.8 0.0082 15.9 1.9 1.5 1 0 0 1 1 1 1 Membrane-associating domain KcnmB2_inactiv PF09303.5 EGD97800.1 - 0.0042 16.8 0.4 0.014 15.1 0.3 1.9 1 0 0 1 1 1 1 KCNMB2, ball and chain domain Gag_spuma PF03276.9 EGD97800.1 - 0.04 12.2 7.5 0.064 11.5 5.2 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Ilm1 PF10311.4 EGD97800.1 - 0.051 13.0 0.3 0.098 12.1 0.2 1.5 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF1418 PF07214.7 EGD97800.1 - 0.53 9.9 2.7 0.39 10.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Cupin_1 PF00190.17 EGD97801.1 - 8e-11 41.5 0.1 1.2e-10 40.9 0.1 1.4 1 1 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EGD97801.1 - 3.9e-08 32.6 0.1 5.9e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Cupin domain ARD PF03079.9 EGD97801.1 - 0.00024 21.0 0.0 0.00033 20.6 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.2 EGD97801.1 - 0.0003 20.4 0.1 0.00037 20.1 0.1 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EGD97801.1 - 0.0018 17.9 0.1 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain FdtA PF05523.6 EGD97801.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 WxcM-like, C-terminal GPI PF06560.6 EGD97801.1 - 0.048 12.6 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) AMNp_N PF10423.4 EGD97801.1 - 0.076 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus Cullin PF00888.17 EGD97802.1 - 6.3e-197 655.7 6.9 9.4e-197 655.1 4.7 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGD97802.1 - 9.4e-28 95.8 3.3 9.4e-28 95.8 2.3 2.6 3 0 0 3 3 3 1 Cullin protein neddylation domain WGG PF10273.4 EGD97802.1 - 0.097 12.7 0.2 27 4.9 0.0 3.1 2 0 0 2 2 2 0 Pre-rRNA-processing protein TSR2 Kinase-PPPase PF03618.9 EGD97802.1 - 0.87 9.0 7.6 5.9 6.3 0.3 2.3 2 0 0 2 2 2 0 Kinase/pyrophosphorylase Avl9 PF09794.4 EGD97803.1 - 6.1e-146 485.7 0.0 9e-146 485.1 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EGD97803.1 - 1.4e-08 34.3 0.3 0.00047 19.8 0.0 2.7 1 1 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 EGD97803.1 - 1.9e-08 33.9 7.0 1.4e-07 31.1 0.2 3.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) APC_CDC26 PF10471.4 EGD97803.1 - 0.42 11.3 6.5 0.14 12.9 2.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Pkinase PF00069.20 EGD97804.1 - 3e-72 242.8 0.0 3.9e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97804.1 - 3.1e-32 111.6 0.0 3.9e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD97804.1 - 1.4e-05 24.2 0.1 5.6e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD97804.1 - 0.00013 21.0 0.0 0.016 14.1 0.0 2.2 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 EGD97804.1 - 0.00029 20.6 0.1 0.0015 18.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGD97804.1 - 0.038 13.3 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF1510 PF07423.6 EGD97806.1 - 0.0047 16.3 0.6 0.0054 16.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) FLO_LFY PF01698.11 EGD97806.1 - 0.0083 15.0 5.8 0.0089 14.9 4.1 1.1 1 0 0 1 1 1 1 Floricaula / Leafy protein IncA PF04156.9 EGD97806.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 IncA protein U79_P34 PF03064.11 EGD97806.1 - 0.012 15.1 6.4 0.015 14.8 4.5 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 BSMAP PF12280.3 EGD97806.1 - 0.031 14.1 0.5 0.034 14.0 0.3 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein Ctr PF04145.10 EGD97806.1 - 0.14 12.2 1.3 0.16 12.0 0.9 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Peptidase_S49_N PF08496.5 EGD97806.1 - 0.62 9.8 2.4 0.87 9.3 1.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.7 EGD97806.1 - 0.9 9.3 4.4 1.1 9.1 3.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CAF-1_p150 PF11600.3 EGD97806.1 - 1.2 8.4 27.6 1.6 8.0 19.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1777 PF08648.7 EGD97806.1 - 1.5 8.5 33.1 1.8 8.2 23.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DDHD PF02862.12 EGD97806.1 - 1.6 8.4 6.7 2 8.1 4.6 1.1 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.8 EGD97806.1 - 2.3 6.8 15.2 2.8 6.5 10.5 1.1 1 0 0 1 1 1 0 Paf1 MIP-T3 PF10243.4 EGD97806.1 - 3.6 5.9 23.5 4.5 5.6 16.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 YqfQ PF14181.1 EGD97806.1 - 4.3 7.3 7.4 5.7 6.9 5.1 1.1 1 0 0 1 1 1 0 YqfQ-like protein RNA_polI_A34 PF08208.6 EGD97806.1 - 5.5 6.6 12.7 7 6.2 8.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 zf-C2H2 PF00096.21 EGD97807.1 - 0.47 10.9 6.4 3.3 8.2 0.1 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.5 EGD97808.1 - 1.4e-64 217.9 0.0 5e-64 216.0 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 DUF243 PF03103.12 EGD97808.1 - 0.018 15.1 1.1 0.28 11.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF243) DUF3328 PF11807.3 EGD97809.1 - 3.6e-46 157.5 0.3 5.4e-46 157.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4343 PF14243.1 EGD97809.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) DUF1688 PF07958.6 EGD97810.1 - 0.086 11.3 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) Palm_thioest PF02089.10 EGD97812.1 - 4.3e-66 222.7 0.0 5.7e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 EGD97812.1 - 6.6e-05 22.8 0.0 7.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD97812.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD97812.1 - 0.0026 17.3 0.0 0.0056 16.2 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 EGD97812.1 - 0.0068 15.5 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Acetyltransf_1 PF00583.19 EGD97813.1 - 3.7e-10 39.7 0.0 6.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD97813.1 - 7e-07 29.3 0.1 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD97813.1 - 0.0041 17.2 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD97813.1 - 0.0066 16.1 0.0 0.025 14.3 0.0 2.0 2 1 0 2 2 2 1 FR47-like protein MOZ_SAS PF01853.13 EGD97813.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family DUF3638 PF12340.3 EGD97814.1 - 7.7e-104 345.6 0.1 1.2e-103 345.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EGD97814.1 - 1.1e-15 56.4 0.4 5.1e-14 51.1 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3645) CENP-L PF13092.1 EGD97815.1 - 8.2e-62 207.7 0.1 1.1e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Sulfate_transp PF00916.15 EGD97816.1 - 6.4e-50 169.7 6.2 6.4e-50 169.7 4.3 1.5 1 1 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 EGD97816.1 - 1.3e-15 56.7 0.0 2.3e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EGD97816.1 - 0.00086 19.2 0.0 0.0023 17.9 0.0 1.8 1 1 0 1 1 1 1 STAS domain EIF_2_alpha PF07541.7 EGD97817.1 - 1.8e-37 127.5 0.0 3.7e-37 126.5 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EGD97817.1 - 2.5e-13 49.8 0.9 4.8e-13 48.9 0.6 1.4 1 0 0 1 1 1 1 S1 RNA binding domain SPOC PF07744.8 EGD97817.1 - 0.0019 18.6 0.1 0.0099 16.3 0.0 2.0 2 0 0 2 2 2 1 SPOC domain PKD_channel PF08016.7 EGD97818.1 - 5.4e-08 31.6 18.7 5.1e-07 28.4 11.1 2.6 1 1 1 2 2 2 1 Polycystin cation channel DUF3782 PF12644.2 EGD97818.1 - 0.14 12.0 0.1 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) CAML PF14963.1 EGD97818.1 - 2.8 7.2 10.1 0.22 10.8 2.9 2.0 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand FYVE PF01363.16 EGD97819.1 - 7.1e-22 77.0 24.8 9.1e-17 60.7 4.0 3.2 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 EGD97819.1 - 1.4e-05 25.1 7.6 0.007 16.4 0.0 3.0 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding DUF3505 PF12013.3 EGD97819.1 - 0.012 15.8 3.3 0.037 14.2 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3505) Seryl_tRNA_N PF02403.17 EGD97819.1 - 0.039 13.9 1.4 0.11 12.4 1.0 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RE_BstXI PF09552.5 EGD97819.1 - 0.14 11.1 0.4 2 7.3 0.0 2.2 2 0 0 2 2 2 0 BstXI restriction endonuclease Fer4_21 PF14697.1 EGD97819.1 - 0.42 10.5 13.4 0.024 14.4 3.6 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain E1-E2_ATPase PF00122.15 EGD97820.1 - 2.1e-23 82.6 0.0 6.2e-23 81.0 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGD97820.1 - 7.3e-17 62.4 0.6 1.6e-16 61.4 0.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGD97820.1 - 2.7e-13 50.5 2.8 1.4e-12 48.2 1.9 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD97820.1 - 0.00021 21.1 0.0 0.00057 19.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGD97820.1 - 0.00039 20.0 0.3 0.0038 16.8 0.1 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EGD97820.1 - 0.042 13.1 0.1 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase AA_permease_2 PF13520.1 EGD97822.1 - 4.4e-60 203.4 51.4 5.4e-60 203.1 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD97822.1 - 5.2e-23 81.1 39.7 8.2e-23 80.4 27.5 1.2 1 0 0 1 1 1 1 Amino acid permease GLTP PF08718.6 EGD97823.1 - 5.1e-46 156.3 0.0 6.8e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Lebercilin PF15619.1 EGD97823.1 - 0.089 12.2 1.8 6.3 6.1 0.0 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BLVR PF06375.6 EGD97824.1 - 0.86 9.4 12.5 0.9 9.3 8.7 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 EGD97824.1 - 2.2 8.0 9.1 2.2 8.0 6.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MRL1 PF13003.2 EGD97824.1 - 3.1 7.6 7.0 3.1 7.6 4.8 1.0 1 0 0 1 1 1 0 Ribosomal protein L1 DUF3812 PF12757.2 EGD97824.1 - 6.9 6.6 12.0 7.4 6.5 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3812) DUF3915 PF13054.1 EGD97824.1 - 8 6.4 6.7 8.9 6.2 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF1682 PF07946.9 EGD97824.1 - 9 5.0 13.5 8.6 5.1 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PH_4 PF15404.1 EGD97825.1 - 1.2e-27 96.6 0.3 1.2e-27 96.6 0.2 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain Spo7_2_N PF15407.1 EGD97825.1 - 4.3e-19 67.7 0.0 1e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 EGD97825.1 - 1.2e-05 25.3 0.1 0.017 15.2 0.0 3.3 2 2 0 2 2 2 2 PH domain PH_6 PF15406.1 EGD97825.1 - 0.0017 18.4 0.1 0.18 11.8 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 EGD97825.1 - 0.041 14.0 0.0 0.61 10.2 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain NAD_binding_10 PF13460.1 EGD97826.1 - 2.1e-06 27.8 0.0 2.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGD97826.1 - 0.0006 19.1 0.0 0.0025 17.0 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EGD97826.1 - 0.027 14.4 0.1 0.078 12.9 0.0 1.9 2 1 0 2 2 2 0 TrkA-N domain TFIIS_C PF01096.13 EGD97827.1 - 7.4e-19 67.1 2.1 7.4e-19 67.1 1.4 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGD97827.1 - 2e-05 24.1 7.9 3.7e-05 23.3 2.1 3.0 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EGD97827.1 - 0.012 15.4 5.2 0.26 11.1 0.5 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 EGD97827.1 - 0.11 12.4 4.7 1.4 9.0 0.1 2.7 2 2 0 2 2 2 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.1 EGD97827.1 - 0.17 12.1 1.6 0.46 10.7 0.3 2.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Elf1 PF05129.8 EGD97827.1 - 0.21 11.2 2.4 2.8 7.7 0.1 2.5 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like IBR PF01485.16 EGD97827.1 - 0.26 11.1 7.6 1.8 8.5 0.2 2.9 2 1 0 2 2 2 0 IBR domain C1_3 PF07649.7 EGD97827.1 - 0.62 10.1 0.2 0.62 10.1 0.1 2.5 3 0 0 3 3 3 0 C1-like domain DZR PF12773.2 EGD97827.1 - 0.82 9.5 6.4 0.29 10.9 0.3 2.3 2 1 0 2 2 2 0 Double zinc ribbon Rubredoxin PF00301.15 EGD97827.1 - 1 9.2 7.4 3.9 7.4 0.1 3.4 3 0 0 3 3 3 0 Rubredoxin NOB1_Zn_bind PF08772.6 EGD97827.1 - 1.3 8.8 3.7 0.37 10.6 0.3 1.8 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_4 PF13717.1 EGD97827.1 - 2.8 7.7 11.9 13 5.5 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGD97827.1 - 2.8 7.5 11.4 17 5.1 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 EGD97827.1 - 3.3 7.2 7.9 0.48 9.9 1.1 2.7 2 1 0 2 2 2 0 InsA N-terminal domain zf-H2C2_2 PF13465.1 EGD97827.1 - 3.9 7.9 12.3 5.3 7.5 0.2 3.6 4 0 0 4 4 4 0 Zinc-finger double domain GTP_EFTU PF00009.22 EGD97828.1 - 4.7e-43 146.8 0.0 8.4e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGD97828.1 - 5.3e-37 125.9 0.1 1.9e-36 124.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGD97828.1 - 2e-17 63.0 1.7 5.3e-17 61.7 1.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EGD97828.1 - 1.2e-05 24.8 0.5 1.2e-05 24.8 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 PDZ PF00595.19 EGD97828.1 - 0.19 11.9 1.2 0.68 10.1 0.1 2.4 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Chalcone PF02431.10 EGD97829.1 - 1.1e-62 210.9 0.0 1.5e-62 210.5 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Glutaredoxin PF00462.19 EGD97830.1 - 1.8e-20 72.6 0.0 2.5e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EGD97830.1 - 0.033 14.3 0.0 0.07 13.3 0.0 1.5 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 EGD97830.1 - 0.045 14.0 0.1 0.072 13.3 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF1191 PF06697.7 EGD97833.1 - 0.03 13.1 0.0 0.058 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) PAT1 PF09770.4 EGD97833.1 - 0.061 11.5 6.2 0.074 11.2 4.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Adeno_E3_CR2 PF02439.10 EGD97833.1 - 1.8 8.1 4.4 3.8 7.1 3.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TFIIA PF03153.8 EGD97833.1 - 3.2 7.5 9.8 4.8 6.9 6.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EB1 PF03271.12 EGD97834.1 - 1.5e-17 63.3 0.5 2.8e-17 62.4 0.4 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EGD97834.1 - 2.3e-07 30.7 0.5 3.8e-07 30.1 0.3 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.11 EGD97834.1 - 0.0034 15.6 0.0 0.0049 15.1 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like ADH_zinc_N_2 PF13602.1 EGD97835.1 - 1.7e-12 48.3 0.0 2.7e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EGD97835.1 - 3.2e-11 42.8 0.0 5.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase WD40 PF00400.27 EGD97836.1 - 7.4e-40 133.4 7.8 1e-09 37.9 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.2 EGD97836.1 - 1.2e-09 37.7 0.1 2.5e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD97836.1 - 1.3e-05 24.6 0.1 2.7e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ PF01011.16 EGD97836.1 - 0.00037 19.8 0.0 3 7.5 0.0 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.1 EGD97836.1 - 0.00043 19.8 0.4 0.0031 17.0 0.1 2.4 2 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 EGD97836.1 - 0.015 13.4 0.9 2.5 6.1 0.0 3.2 2 1 0 2 2 2 0 Nucleoporin Nup120/160 STE PF02200.11 EGD97836.1 - 0.17 12.0 0.1 0.54 10.4 0.0 1.8 2 0 0 2 2 2 0 STE like transcription factor ADH_N PF08240.7 EGD97837.1 - 2.1e-26 91.8 4.3 3.8e-26 90.9 3.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD97837.1 - 2.6e-16 59.3 0.0 4.4e-15 55.3 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGD97837.1 - 0.00016 20.9 0.1 0.00029 20.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DHDPS PF00701.17 EGD97838.1 - 1.3e-35 122.4 0.0 4.1e-34 117.5 0.0 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.17 EGD97839.1 - 2.2e-08 34.6 0.2 8e-08 32.8 0.1 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold E1-E2_ATPase PF00122.15 EGD97840.1 - 4e-58 196.1 0.1 8.8e-58 195.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD97840.1 - 8e-46 155.8 8.2 8e-46 155.8 5.7 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD97840.1 - 5.4e-26 92.3 0.0 1.3e-25 91.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD97840.1 - 1.9e-16 59.7 0.0 3.9e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGD97840.1 - 1.1e-12 48.5 0.0 2.5e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD97840.1 - 7e-08 31.8 0.1 3.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGD97840.1 - 1.3e-05 24.9 0.0 0.00069 19.2 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EGD97840.1 - 0.054 13.4 0.0 0.054 13.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) P16-Arc PF04699.9 EGD97841.1 - 9.1e-59 197.8 0.0 1.1e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Methyltransf_11 PF08241.7 EGD97842.1 - 1.7e-08 34.8 0.0 3.4e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD97842.1 - 6.4e-07 29.2 0.0 1.2e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD97842.1 - 5.2e-05 23.6 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD97842.1 - 7.7e-05 22.3 0.0 0.00019 21.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD97842.1 - 0.0062 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGD97842.1 - 0.0082 16.4 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF2622 PF11080.3 EGD97842.1 - 0.12 12.2 0.0 0.82 9.5 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2622) Dynactin_p62 PF05502.8 EGD97843.1 - 7.2e-178 592.2 0.1 9e-178 591.9 0.1 1.1 1 0 0 1 1 1 1 Dynactin p62 family Ribosomal_S7e PF01251.13 EGD97844.1 - 2e-79 265.4 0.3 2.2e-79 265.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e XFP_N PF09364.5 EGD97845.1 - 8.6e-154 511.6 0.0 1.2e-153 511.2 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EGD97845.1 - 1e-67 227.5 0.0 1.7e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EGD97845.1 - 1.3e-67 226.8 0.0 2e-67 226.2 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Acetate_kinase PF00871.12 EGD97846.1 - 5.9e-89 298.2 0.0 5.8e-88 295.0 0.0 1.9 1 1 0 1 1 1 1 Acetokinase family Adeno_E1B_55K_N PF04623.7 EGD97847.1 - 0.093 13.2 0.4 0.12 12.9 0.3 1.1 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus Ras PF00071.17 EGD97849.1 - 2.1e-55 186.5 0.0 2.7e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD97849.1 - 4.7e-20 72.2 0.0 6.8e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD97849.1 - 4.9e-13 48.7 0.0 8e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGD97849.1 - 1.5e-05 24.2 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGD97849.1 - 1.7e-05 24.3 0.0 3.9e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGD97849.1 - 0.00031 20.6 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EGD97849.1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.20 EGD97850.1 - 1.1e-38 132.9 0.0 3.4e-38 131.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97850.1 - 7e-27 94.1 0.0 1.7e-26 92.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD97850.1 - 0.0011 17.9 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGD97850.1 - 0.02 13.9 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD97850.1 - 0.11 12.2 0.0 9.5 5.8 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Vfa1 PF08432.5 EGD97851.1 - 0.77 9.7 29.5 1.6 8.7 20.4 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF572 PF04502.8 EGD97851.1 - 3.1 6.9 36.2 5.2 6.1 25.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4098 PF13345.1 EGD97852.1 - 0.0061 16.4 0.0 0.55 10.2 0.0 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4098) Sugar_tr PF00083.19 EGD97853.1 - 2.5e-78 263.6 30.9 2.9e-78 263.4 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD97853.1 - 1.3e-12 47.1 40.9 5.2e-09 35.2 9.6 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGD97853.1 - 0.072 13.1 7.3 0.18 11.8 0.3 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) Dynamin_N PF00350.18 EGD97854.1 - 2.5e-17 63.2 0.0 4e-16 59.2 0.0 3.0 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EGD97854.1 - 1.7e-06 27.9 0.0 0.00013 21.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGD97854.1 - 0.00025 21.3 0.9 0.00089 19.5 0.0 2.4 2 1 0 2 2 2 1 ABC transporter Adeno_IVa2 PF02456.10 EGD97854.1 - 0.00072 18.3 0.0 0.0015 17.2 0.0 1.4 1 0 0 1 1 1 1 Adenovirus IVa2 protein DUF258 PF03193.11 EGD97854.1 - 0.0033 16.6 0.0 0.011 14.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EGD97854.1 - 0.004 17.6 0.0 0.018 15.5 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 EGD97854.1 - 0.044 14.6 0.0 0.38 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGD97854.1 - 0.074 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.11 EGD97854.1 - 0.098 11.7 0.1 0.098 11.7 0.1 2.7 4 0 0 4 4 4 0 AIG1 family ATP-grasp_2 PF08442.5 EGD97854.1 - 0.13 11.5 2.4 0.07 12.4 0.1 1.7 2 0 0 2 2 2 0 ATP-grasp domain DUF4451 PF14616.1 EGD97855.1 - 2.3e-32 111.3 0.5 4.1e-32 110.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) TPR_11 PF13414.1 EGD97856.1 - 1.4e-44 149.5 15.5 6e-17 61.0 0.8 5.8 3 2 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 EGD97856.1 - 1e-35 119.8 9.5 7e-07 28.5 0.0 7.6 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 EGD97856.1 - 1e-34 115.5 11.6 7.8e-07 28.5 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.26 EGD97856.1 - 4.2e-27 93.6 5.0 4.9e-27 93.4 0.7 3.1 4 0 0 4 4 3 1 DnaJ domain TPR_14 PF13428.1 EGD97856.1 - 1.5e-23 81.1 10.7 0.00036 20.8 0.0 9.2 3 3 6 9 9 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EGD97856.1 - 9.1e-23 80.3 9.8 9.4e-06 25.8 0.0 5.7 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGD97856.1 - 4.2e-22 78.2 19.2 4.5e-06 27.1 1.3 6.0 4 2 1 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGD97856.1 - 3.4e-20 70.5 9.6 0.0041 17.2 0.1 7.1 6 0 0 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 EGD97856.1 - 4.9e-16 58.6 3.0 1.1e-05 25.4 0.1 3.9 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGD97856.1 - 1.3e-15 57.0 13.1 1.3e-05 25.0 0.4 5.4 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGD97856.1 - 6.7e-14 50.5 9.8 0.022 14.5 0.0 7.4 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 EGD97856.1 - 5.2e-13 48.6 4.9 0.00077 19.2 0.0 5.0 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGD97856.1 - 1.6e-11 43.1 12.9 0.0032 17.1 0.0 7.7 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGD97856.1 - 1e-09 38.1 13.2 0.00065 19.9 0.0 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGD97856.1 - 1.9e-08 33.7 3.6 0.031 13.3 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.12 EGD97856.1 - 3e-06 27.5 3.5 0.001 19.3 0.2 3.9 3 1 0 3 3 3 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 EGD97856.1 - 3.5e-06 26.7 4.8 0.16 11.9 0.0 4.9 2 1 3 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 EGD97856.1 - 0.00013 22.0 5.9 6 7.0 0.1 4.8 3 2 1 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 EGD97856.1 - 0.00024 19.9 0.1 0.07 11.8 0.0 2.4 2 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_E PF04733.9 EGD97856.1 - 0.0011 18.2 0.4 6.3 5.9 0.0 3.2 3 0 0 3 3 3 0 Coatomer epsilon subunit TPR_10 PF13374.1 EGD97856.1 - 0.0013 18.6 12.3 1 9.3 0.0 6.0 7 0 0 7 7 5 1 Tetratricopeptide repeat MIT PF04212.13 EGD97856.1 - 0.027 14.3 3.4 0.84 9.5 0.1 4.2 2 2 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.9 EGD97856.1 - 0.35 11.4 0.0 0.35 11.4 0.0 5.7 6 0 0 6 6 4 0 Tetratricopeptide repeat HHH_8 PF14716.1 EGD97856.1 - 1.4 9.1 5.2 2.5 8.3 0.1 3.9 5 0 0 5 5 4 0 Helix-hairpin-helix domain Med3 PF11593.3 EGD97856.1 - 3.8 6.6 24.1 0.085 12.0 7.8 2.5 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal DUF3366 PF11846.3 EGD97856.1 - 9.7 6.0 8.3 5.6 6.7 0.5 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3366) ACBP PF00887.14 EGD97857.1 - 0.095 12.3 0.1 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Acyl CoA binding protein UPF0029 PF01205.14 EGD97859.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 DUF4508 PF14969.1 EGD97859.1 - 1.8 8.5 7.2 0.22 11.5 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) PI3_PI4_kinase PF00454.22 EGD97862.1 - 0.037 13.5 0.1 0.068 12.6 0.1 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase DUF3442 PF11924.3 EGD97865.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3442) APH PF01636.18 EGD97866.1 - 1.9e-09 37.6 0.1 2.2e-08 34.1 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGD97866.1 - 0.027 13.1 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Protoglobin PF11563.3 EGD97868.1 - 2.5e-50 170.2 0.0 2.9e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Protoglobin DUF1499 PF07386.6 EGD97868.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) CN_hydrolase PF00795.17 EGD97869.1 - 1.7e-25 89.4 0.0 4.9e-25 87.9 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EGD97869.1 - 2.7e-24 85.4 0.0 6.1e-24 84.2 0.0 1.5 1 1 0 1 1 1 1 NAD synthase Pkinase PF00069.20 EGD97871.1 - 8.1e-61 205.4 0.0 1e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97871.1 - 6.1e-35 120.5 0.0 8e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD97871.1 - 6.5e-09 35.1 0.0 9.6e-09 34.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGD97871.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec39 PF08314.6 EGD97872.1 - 1.4e-201 671.1 0.0 1.6e-201 670.9 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.4 EGD97873.1 - 0.00032 20.6 0.0 0.00038 20.3 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 EGD97873.1 - 0.00064 19.7 0.7 0.0016 18.5 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 EGD97873.1 - 0.0057 16.6 0.2 0.0083 16.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DnaJ PF00226.26 EGD97873.1 - 0.034 13.8 0.1 0.043 13.5 0.1 1.2 1 0 0 1 1 1 0 DnaJ domain DUF3535 PF12054.3 EGD97874.1 - 9.2e-150 499.1 0.0 9.8e-149 495.7 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EGD97874.1 - 6.7e-72 241.8 0.0 1.1e-71 241.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EGD97874.1 - 4.8e-17 60.4 11.1 0.0051 16.7 0.1 9.9 11 0 0 11 11 11 4 HEAT repeat Helicase_C PF00271.26 EGD97874.1 - 2.2e-14 53.0 0.0 6.4e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 EGD97874.1 - 4e-06 27.0 12.8 0.11 12.8 0.0 8.0 7 2 0 8 8 8 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EGD97874.1 - 4.6e-06 26.9 0.1 0.13 12.6 0.0 4.0 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGD97874.1 - 7e-06 26.3 7.3 1.5 9.4 0.0 7.7 8 0 0 8 8 8 1 HEAT-like repeat CLASP_N PF12348.3 EGD97874.1 - 0.00014 21.3 0.0 0.063 12.6 0.0 4.0 3 1 1 4 4 4 1 CLASP N terminal Erythro_esteras PF05139.9 EGD97876.1 - 1.2e-139 465.3 1.2 1.5e-139 465.0 0.8 1.1 1 0 0 1 1 1 1 Erythromycin esterase Scs3p PF10261.4 EGD97878.1 - 7.5e-62 208.4 1.9 9.4e-62 208.1 1.3 1.0 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DAP_B PF07930.7 EGD97878.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 D-aminopeptidase, domain B Zn_clus PF00172.13 EGD97879.1 - 0.0056 16.5 12.3 0.011 15.6 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EBP PF05241.7 EGD97880.1 - 4.7e-06 25.7 2.7 1.3e-05 24.3 1.9 1.9 1 1 0 1 1 1 1 Emopamil binding protein tRNA-synt_1e PF01406.14 EGD97881.1 - 1.4e-28 99.9 0.0 1.8e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.20 EGD97883.1 - 2.4e-12 46.5 0.0 3e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD97883.1 - 2.5e-12 46.4 0.0 9.8e-11 41.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PTP_N PF12453.3 EGD97884.1 - 2 8.1 6.8 0.31 10.6 2.2 1.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal Atg8 PF02991.11 EGD97886.1 - 1.5e-34 118.0 0.0 1.7e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EGD97886.1 - 0.0017 18.4 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Peptidase_S10 PF00450.17 EGD97887.1 - 2.2e-93 313.7 0.1 2.7e-93 313.3 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGD97887.1 - 0.024 14.5 0.0 0.83 9.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Guanylate_cyc_2 PF09778.4 EGD97887.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Guanylylate cyclase Methyltransf_16 PF10294.4 EGD97888.1 - 1.8e-14 53.6 0.0 2.4e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EGD97888.1 - 0.0003 20.5 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EGD97888.1 - 0.004 16.3 0.0 0.0065 15.6 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.12 EGD97888.1 - 0.031 13.2 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family PrmA PF06325.8 EGD97888.1 - 0.034 13.2 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EGD97888.1 - 0.062 13.8 0.0 0.093 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Antimicrobial_1 PF08018.6 EGD97888.1 - 0.14 12.0 0.7 0.53 10.2 0.2 2.0 2 0 0 2 2 2 0 Frog antimicrobial peptide MFS_1 PF07690.11 EGD97890.1 - 1.5e-38 132.4 31.8 4.6e-36 124.2 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD97890.1 - 3e-07 29.3 9.6 3e-07 29.3 6.7 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EGD97890.1 - 0.016 13.6 18.6 0.076 11.4 0.3 3.0 3 1 0 3 3 3 0 MFS/sugar transport protein Trp_oprn_chp PF09534.5 EGD97890.1 - 4.7 6.7 7.9 0.33 10.5 0.3 2.6 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) F-box PF00646.28 EGD97892.1 - 0.009 15.6 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD97892.1 - 0.025 14.2 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like AlaDh_PNT_N PF05222.10 EGD97893.1 - 1.8e-27 96.0 0.0 2.7e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EGD97893.1 - 1.5e-12 47.3 0.0 2.4e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain BAR PF03114.13 EGD97894.1 - 1.2e-63 214.7 7.5 1.5e-63 214.4 5.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EGD97894.1 - 5.2e-13 48.1 0.0 1.1e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD97894.1 - 3.2e-12 45.8 0.0 5.6e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGD97894.1 - 5.5e-08 32.1 0.0 1.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EGD97894.1 - 0.036 13.3 7.4 0.39 9.9 0.0 2.3 2 0 0 2 2 2 0 Vps5 C terminal like TMPIT PF07851.8 EGD97894.1 - 1.8 7.5 6.2 0.31 10.0 0.7 1.9 1 1 1 2 2 2 0 TMPIT-like protein APG6 PF04111.7 EGD97894.1 - 3.5 6.5 11.9 13 4.6 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Asp PF00026.18 EGD97895.1 - 6.9e-63 212.7 6.1 8.3e-63 212.5 4.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGD97895.1 - 0.00039 20.8 0.8 0.24 11.9 0.2 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EGD97895.1 - 0.0005 20.0 0.2 0.0017 18.3 0.1 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EGD97895.1 - 0.001 18.6 0.0 0.0026 17.3 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal AvrPphF-ORF-2 PF09143.5 EGD97895.1 - 0.061 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 AvrPphF-ORF-2 GST_N_3 PF13417.1 EGD97896.1 - 3.3e-17 62.4 0.0 7.5e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD97896.1 - 5.2e-15 55.3 0.0 1.1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD97896.1 - 9e-11 41.6 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD97896.1 - 1e-09 38.2 0.0 1.6e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD97896.1 - 0.0012 19.3 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGD97896.1 - 0.0091 15.8 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ERG4_ERG24 PF01222.12 EGD97897.1 - 9.9e-94 314.2 16.0 1.2e-93 314.0 11.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGD97897.1 - 0.0059 15.9 0.4 0.013 14.8 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) AAA_16 PF13191.1 EGD97898.1 - 0.0027 17.7 0.5 0.088 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain KaiC PF06745.8 EGD97898.1 - 0.074 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EGD97898.1 - 0.076 13.1 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATP_transf PF09830.4 EGD97899.1 - 5.1e-13 48.6 0.5 8.6e-13 47.8 0.0 1.7 2 0 0 2 2 2 1 ATP adenylyltransferase Copper-bind PF00127.15 EGD97900.1 - 0.0004 20.5 0.1 0.00069 19.8 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family LEA_6 PF10714.4 EGD97900.1 - 0.023 14.4 3.5 0.039 13.7 2.4 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 Cas_csx3 PF09620.5 EGD97900.1 - 0.035 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Cupredoxin_1 PF13473.1 EGD97900.1 - 0.064 13.1 0.2 0.3 10.9 0.1 1.9 1 1 1 2 2 2 0 Cupredoxin-like domain Aminotran_5 PF00266.14 EGD97901.1 - 4e-96 321.9 0.0 4.8e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGD97901.1 - 2.9e-08 33.1 0.0 4.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGD97901.1 - 8.8e-06 24.9 0.0 3.1e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EGD97901.1 - 0.0046 15.4 0.0 0.0066 14.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 EGD97901.1 - 0.072 11.3 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IDO PF01231.13 EGD97902.1 - 5.5e-155 515.9 0.0 6.3e-155 515.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.8 EGD97903.1 - 2.5e-36 124.0 0.0 4.1e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EGD97903.1 - 1.4e-20 72.6 0.0 1.4e-19 69.4 0.0 2.2 2 0 0 2 2 2 1 Vps23 core domain ADIP PF11559.3 EGD97903.1 - 0.004 17.0 1.7 0.0063 16.4 1.2 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 EGD97903.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Snapin_Pallidin PF14712.1 EGD97903.1 - 0.079 13.2 0.5 0.13 12.5 0.4 1.4 1 0 0 1 1 1 0 Snapin/Pallidin WEMBL PF05701.6 EGD97903.1 - 0.12 10.8 0.2 0.16 10.3 0.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 EGD97903.1 - 0.12 11.4 3.7 0.19 10.8 2.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein WD40 PF00400.27 EGD97904.1 - 7e-22 76.4 5.9 4.3e-05 23.2 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Pro_CA PF00484.14 EGD97907.1 - 1.7e-43 148.2 0.2 2.2e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase WSK PF03832.8 EGD97909.1 - 0.14 11.4 0.7 0.43 9.9 0.5 1.9 1 0 0 1 1 1 0 WSK motif Velvet PF11754.3 EGD97910.1 - 1.3e-56 191.4 0.5 9.1e-56 188.6 0.4 2.0 1 1 0 1 1 1 1 Velvet factor MOZ_SAS PF01853.13 EGD97912.1 - 1.5e-78 262.4 0.0 2.5e-78 261.6 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family PHD_2 PF13831.1 EGD97912.1 - 0.0026 17.0 5.3 0.01 15.1 3.6 2.1 1 0 0 1 1 1 1 PHD-finger zf-Sec23_Sec24 PF04810.10 EGD97912.1 - 0.045 13.3 0.1 0.045 13.3 0.1 2.6 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger PHD PF00628.24 EGD97912.1 - 0.12 12.0 16.6 0.038 13.6 8.7 2.2 2 0 0 2 2 2 0 PHD-finger HTH_45 PF14947.1 EGD97912.1 - 0.19 11.5 0.1 0.82 9.5 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix PetG PF02529.10 EGD97913.1 - 0.04 13.4 0.2 0.082 12.4 0.1 1.5 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Acetyltransf_2 PF00797.12 EGD97914.1 - 2.7e-40 138.4 0.0 3.8e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase LMSTEN PF07988.7 EGD97914.1 - 0.14 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 LMSTEN motif Methyltransf_6 PF03737.10 EGD97915.1 - 2.3e-24 85.9 0.1 3.6e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase NTP_transf_3 PF12804.2 EGD97915.1 - 0.08 13.0 0.0 0.97 9.4 0.0 2.1 1 1 0 2 2 2 0 MobA-like NTP transferase domain Thiolase_N PF00108.18 EGD97916.1 - 9.3e-78 260.8 1.3 9.3e-78 260.8 0.9 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGD97916.1 - 4e-44 148.9 0.2 7.8e-44 148.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain GFO_IDH_MocA PF01408.17 EGD97918.1 - 2e-20 73.4 0.2 4.6e-20 72.3 0.1 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DUF4470 PF14737.1 EGD97918.1 - 0.14 11.8 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4470) APH PF01636.18 EGD97919.1 - 1.5e-09 37.9 0.2 5.4e-09 36.1 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD97919.1 - 2e-06 27.5 0.0 2.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EGD97919.1 - 0.067 12.2 0.0 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Drf_GBD PF06371.8 EGD97920.1 - 2.4e-19 69.4 5.3 2.7e-17 62.7 3.7 2.5 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain CRM1_C PF08767.6 EGD97920.1 - 0.046 12.6 0.2 0.072 12.0 0.1 1.2 1 0 0 1 1 1 0 CRM1 C terminal Snf7 PF03357.16 EGD97921.1 - 3.2e-43 147.0 12.7 3.9e-43 146.7 8.8 1.1 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 EGD97921.1 - 0.00055 19.4 3.9 0.00055 19.4 2.7 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) DUF3584 PF12128.3 EGD97921.1 - 0.00062 17.2 4.3 0.00094 16.6 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF1395 PF07160.7 EGD97921.1 - 0.0047 16.4 4.6 0.074 12.5 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1395) NPV_P10 PF05531.7 EGD97921.1 - 0.0097 16.1 5.5 0.34 11.1 1.4 2.6 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.2 EGD97921.1 - 0.011 15.0 6.2 0.12 11.6 3.1 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.4 EGD97921.1 - 0.016 15.0 5.9 0.29 10.9 3.6 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.8 EGD97921.1 - 0.025 14.5 6.1 0.018 14.9 2.1 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 EGD97921.1 - 0.031 13.8 3.2 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 IncA protein DUF4140 PF13600.1 EGD97921.1 - 0.05 14.0 2.4 0.79 10.2 0.0 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.15 EGD97921.1 - 0.055 13.2 5.7 0.76 9.5 0.0 3.5 2 1 1 3 3 3 0 Prefoldin subunit Atg14 PF10186.4 EGD97921.1 - 0.12 11.3 5.4 0.17 10.8 3.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin PF02996.12 EGD97921.1 - 0.13 11.8 3.9 7.2 6.2 0.0 3.3 2 1 3 5 5 5 0 Prefoldin subunit PqqD PF05402.7 EGD97921.1 - 0.15 12.1 0.5 0.27 11.2 0.3 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Mnd1 PF03962.10 EGD97921.1 - 0.15 11.6 8.2 0.41 10.2 5.7 1.7 1 1 0 1 1 1 0 Mnd1 family BLOC1_2 PF10046.4 EGD97921.1 - 0.24 11.5 5.2 4.5 7.4 0.5 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 EGD97921.1 - 0.28 10.3 3.4 1.5 7.9 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Spc24 PF08286.6 EGD97921.1 - 0.79 9.4 5.4 3.6 7.3 0.2 3.0 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF4337 PF14235.1 EGD97921.1 - 1.4 8.7 6.3 0.53 10.1 0.9 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4337) Vps51 PF08700.6 EGD97921.1 - 1.7 8.5 6.3 1.9 8.3 0.3 3.1 3 0 0 3 3 3 0 Vps51/Vps67 FliD_N PF02465.13 EGD97921.1 - 2.5 8.5 7.2 22 5.4 2.8 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Uso1_p115_C PF04871.8 EGD97921.1 - 3.7 7.5 8.6 15 5.5 6.0 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region SAPS PF04499.10 EGD97922.1 - 1.6e-175 584.3 0.0 1.6e-175 584.3 0.0 1.9 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein Complex1_51K PF01512.12 EGD97924.1 - 3.1e-38 130.8 0.0 5.4e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EGD97924.1 - 4.9e-18 64.0 1.7 4.9e-18 64.0 1.1 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EGD97924.1 - 2.9e-09 36.6 0.0 6.9e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 SLBB domain TSA PF03249.8 EGD97924.1 - 0.57 8.6 3.0 0.98 7.8 2.0 1.3 1 0 0 1 1 1 0 Type specific antigen Nup96 PF12110.3 EGD97925.1 - 4.2e-86 288.6 0.0 6.4e-86 288.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EGD97925.1 - 4.7e-49 165.8 0.0 8.3e-49 165.0 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EGD97925.1 - 2.5e-20 72.7 212.7 8.9e-10 38.8 29.7 10.8 5 2 5 10 10 10 4 Nucleoporin FG repeat region zf-C3Hc3H PF13891.1 EGD97926.1 - 0.79 9.8 3.6 0.61 10.1 0.4 2.1 1 1 1 2 2 2 0 Potential DNA-binding domain AMP-binding PF00501.23 EGD97927.1 - 1.5e-94 316.7 0.1 1.9e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD97927.1 - 9.6e-23 80.9 1.7 2.4e-20 73.2 0.7 2.9 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain GET2 PF08690.5 EGD97928.1 - 0.00016 21.0 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 GET complex subunit GET2 Pol_alpha_B_N PF08418.5 EGD97928.1 - 1.4 8.4 3.9 2.2 7.7 2.7 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal C2 PF00168.25 EGD97929.1 - 8.4e-22 76.8 0.0 4.3e-14 52.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain CDC45 PF02724.9 EGD97930.1 - 0.32 8.9 2.3 0.44 8.5 1.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.2 EGD97930.1 - 9.4 5.6 8.1 3.9 6.9 3.7 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein IMS PF00817.15 EGD97932.1 - 4.5e-39 133.6 0.0 6.8e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGD97932.1 - 3.3e-09 36.7 0.1 1.5e-08 34.6 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain Reprolysin_4 PF13583.1 EGD97934.1 - 4.7e-60 202.6 1.0 8.4e-60 201.8 0.7 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EGD97934.1 - 5.7e-59 199.3 6.7 5.7e-59 199.3 4.7 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EGD97934.1 - 5.2e-41 140.5 1.4 5.2e-41 140.5 1.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EGD97934.1 - 2.1e-18 67.0 0.2 4.8e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EGD97934.1 - 3.9e-16 59.0 35.7 3.9e-16 59.0 24.7 4.2 3 2 1 4 4 4 1 Disintegrin Pep_M12B_propep PF01562.14 EGD97934.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Reprolysin family propeptide EF-hand_8 PF13833.1 EGD97935.1 - 9.9e-10 37.8 0.2 2e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 EGD97935.1 - 8.4e-09 35.4 1.0 1.2e-08 34.9 0.1 1.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGD97935.1 - 2.1e-07 29.7 1.1 0.00019 20.4 0.1 2.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EGD97935.1 - 1e-06 28.0 1.8 5.9e-06 25.7 0.1 2.6 3 0 0 3 3 3 1 EF-hand domain MgsA_C PF12002.3 EGD97936.1 - 2.3e-57 193.3 0.1 3.9e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EGD97936.1 - 5.5e-14 52.4 0.0 1.3e-13 51.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGD97936.1 - 1.1e-12 47.5 0.0 3.9e-12 45.7 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EGD97936.1 - 8.7e-06 25.0 0.1 0.042 13.0 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGD97936.1 - 2.3e-05 24.1 0.0 0.00067 19.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EGD97936.1 - 5.8e-05 22.6 0.0 0.003 17.0 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 EGD97936.1 - 0.00017 21.7 0.7 0.001 19.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EGD97936.1 - 0.00026 20.5 0.0 0.0007 19.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGD97936.1 - 0.00044 19.9 0.2 0.0025 17.5 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EGD97936.1 - 0.00098 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGD97936.1 - 0.001 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EGD97936.1 - 0.0015 18.5 0.1 0.074 13.0 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EGD97936.1 - 0.0043 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.10 EGD97936.1 - 0.012 15.4 0.2 2.3 8.0 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 EGD97936.1 - 0.014 16.2 0.1 0.038 14.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 EGD97936.1 - 0.014 14.1 0.0 0.049 12.3 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus AAA_30 PF13604.1 EGD97936.1 - 0.022 14.3 0.2 0.27 10.7 0.2 2.2 1 1 1 2 2 2 0 AAA domain DUF927 PF06048.6 EGD97936.1 - 0.03 13.5 0.2 0.055 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) PIF1 PF05970.9 EGD97936.1 - 0.03 13.2 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.1 EGD97936.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGD97936.1 - 0.064 12.9 0.0 4.9 6.7 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase NACHT PF05729.7 EGD97936.1 - 0.07 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EGD97936.1 - 0.088 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EGD97936.1 - 0.096 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 EGD97936.1 - 0.11 11.7 0.0 0.42 9.8 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.1 EGD97936.1 - 0.13 11.7 0.1 7.9 6.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 EGD97936.1 - 0.17 11.0 0.2 2 7.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF258 AAA_13 PF13166.1 EGD97936.1 - 0.27 9.6 0.1 0.43 8.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.16 EGD97937.1 - 1.9e-70 237.6 0.0 2.2e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD97937.1 - 3.1e-05 23.2 0.0 4.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EGD97937.1 - 0.0002 19.7 0.0 0.00047 18.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EGD97937.1 - 0.00045 19.0 0.0 0.0061 15.3 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGD97937.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family KH_1 PF00013.24 EGD97938.1 - 7.1e-42 140.8 8.7 3.3e-13 49.0 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGD97938.1 - 4.1e-34 115.6 4.4 7.9e-11 41.3 0.1 3.8 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EGD97938.1 - 1.3e-13 50.3 3.3 0.00025 20.5 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGD97938.1 - 9.2e-10 38.0 3.7 0.025 14.2 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EGD97938.1 - 8e-05 22.3 2.0 3.4 7.5 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain dUTPase PF00692.14 EGD97938.1 - 0.02 14.3 0.0 3.6 7.0 0.0 3.1 3 0 0 3 3 3 0 dUTPase DUF2587 PF10759.4 EGD97938.1 - 4.6 6.5 9.0 0.46 9.8 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2587) Amidoligase_2 PF12224.3 EGD97939.1 - 1.6e-18 67.2 0.0 2.2e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme HHH_3 PF12836.2 EGD97940.1 - 0.0014 18.5 0.0 1.5 8.8 0.0 2.8 3 0 0 3 3 3 2 Helix-hairpin-helix motif DUF3665 PF12427.3 EGD97940.1 - 0.11 11.8 0.0 21 4.5 0.0 2.7 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase Ald_Xan_dh_C2 PF02738.13 EGD97942.1 - 3.9e-201 669.1 0.3 5.1e-201 668.7 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EGD97942.1 - 1.9e-46 157.6 0.0 3.3e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EGD97942.1 - 1.3e-33 114.9 0.1 7.6e-33 112.5 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EGD97942.1 - 1.2e-28 99.3 0.0 2.7e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EGD97942.1 - 5e-28 96.8 0.0 1.2e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EGD97942.1 - 5.2e-09 35.7 0.6 1.3e-08 34.4 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF2505 PF10698.4 EGD97942.1 - 0.076 12.5 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) AMP-binding PF00501.23 EGD97943.1 - 3e-74 249.9 0.0 4.2e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EGD97943.1 - 2.1e-71 239.7 0.0 3.1e-71 239.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGD97943.1 - 1.3e-11 44.4 0.0 2.7e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGD97943.1 - 4.1e-11 42.9 0.0 9.7e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD97943.1 - 7.3e-08 33.2 0.0 2.4e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EGD97943.1 - 0.00013 20.7 0.0 0.00035 19.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGD97943.1 - 0.0064 16.5 0.0 0.2 11.6 0.0 2.6 1 1 0 1 1 1 1 NADH(P)-binding Condensation PF00668.15 EGD97943.1 - 0.0083 15.0 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Condensation domain RmlD_sub_bind PF04321.12 EGD97943.1 - 0.023 13.5 0.0 0.19 10.6 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain CaM_bdg_C0 PF10562.4 EGD97943.1 - 0.21 11.4 0.2 0.43 10.4 0.1 1.5 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit AAA_17 PF13207.1 EGD97944.1 - 4.1e-05 24.3 0.0 6.2e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGD97944.1 - 0.00028 21.1 0.0 0.00041 20.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PRK PF00485.13 EGD97944.1 - 0.00089 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EGD97944.1 - 0.0017 18.6 0.0 0.012 15.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGD97944.1 - 0.028 14.5 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EGD97944.1 - 0.044 13.3 0.3 0.087 12.3 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EGD97944.1 - 0.058 13.3 0.3 0.13 12.2 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGD97944.1 - 0.064 13.2 0.3 0.11 12.5 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain SNF2_N PF00176.18 EGD97945.1 - 1.3e-33 116.0 0.0 2.4e-30 105.3 0.0 2.5 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD97945.1 - 0.00041 20.1 0.0 0.001 18.8 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HMG_box PF00505.14 EGD97946.1 - 9.1e-22 77.1 0.1 1.8e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGD97946.1 - 1.3e-05 25.4 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain Ribosomal_S6e PF01092.14 EGD97947.1 - 1.1e-34 118.7 0.4 4.4e-30 103.9 0.1 2.6 1 1 1 2 2 2 2 Ribosomal protein S6e DUF2992 PF11208.3 EGD97947.1 - 0.34 10.8 9.1 0.49 10.2 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Pribosyltran_N PF13793.1 EGD97948.1 - 2e-47 159.7 0.5 1.3e-44 150.6 0.1 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGD97948.1 - 1.8e-43 148.4 1.0 1.4e-36 126.0 0.3 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGD97948.1 - 2e-14 53.3 0.6 2.4e-13 49.9 0.3 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGD97948.1 - 0.00087 18.5 0.2 0.0017 17.6 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF913 PF06025.7 EGD97949.1 - 3.1e-132 440.9 0.0 3.1e-132 440.9 0.0 4.4 5 1 1 6 6 6 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EGD97949.1 - 3.3e-95 318.8 0.0 6.9e-95 317.8 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EGD97949.1 - 4.4e-83 279.2 4.6 2.3e-82 276.9 3.2 2.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EGD97949.1 - 1.8e-33 114.6 8.4 1.8e-33 114.6 5.8 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) UBA PF00627.26 EGD97949.1 - 0.00014 21.6 0.0 0.00043 20.0 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain An_peroxidase PF03098.10 EGD97950.1 - 1.4e-100 337.1 0.0 2.4e-98 329.8 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EGD97950.1 - 2.3e-09 36.3 0.0 2.8e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Steroid_dh PF02544.11 EGD97952.1 - 2.5e-31 108.4 0.2 3.2e-31 108.1 0.2 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EGD97952.1 - 2.9e-06 26.7 0.3 3.8e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EGD97952.1 - 8.1e-06 25.9 0.3 1.9e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Halogen_Hydrol PF10112.4 EGD97952.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Glyco_transf_34 PF05637.7 EGD97953.1 - 3.8e-58 196.7 0.0 4.7e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EGD97953.1 - 0.06 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Ribosomal_L28 PF00830.14 EGD97954.1 - 1.7e-17 62.9 0.3 2.8e-17 62.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L28 family TIP49 PF06068.8 EGD97955.1 - 2.8e-186 619.0 0.2 3.2e-186 618.8 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EGD97955.1 - 1.9e-11 44.2 0.3 2.4e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGD97955.1 - 1.3e-10 40.7 0.9 2.5e-06 26.6 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGD97955.1 - 5.6e-06 26.4 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EGD97955.1 - 1.1e-05 25.5 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGD97955.1 - 0.0001 21.9 0.1 0.00028 20.5 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EGD97955.1 - 0.00017 21.5 0.1 0.00042 20.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGD97955.1 - 0.00081 19.1 0.2 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EGD97955.1 - 0.0011 18.1 0.2 0.0028 16.8 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EGD97955.1 - 0.0014 18.0 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EGD97955.1 - 0.0021 17.4 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGD97955.1 - 0.015 14.4 0.1 0.72 8.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EGD97955.1 - 0.016 14.3 0.5 0.096 11.7 0.0 2.3 3 0 0 3 3 3 0 KaiC DnaB_C PF03796.10 EGD97955.1 - 0.019 13.8 0.0 0.039 12.8 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.12 EGD97955.1 - 0.022 14.1 0.1 0.047 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 EGD97955.1 - 0.026 13.5 0.1 0.057 12.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EGD97955.1 - 0.031 14.5 0.3 0.24 11.7 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 EGD97955.1 - 0.054 14.3 0.0 0.14 13.0 0.0 1.9 2 1 0 2 2 1 0 AAA domain V-SNARE PF05008.10 EGD97956.1 - 4.7e-23 81.1 7.3 4.7e-23 81.1 5.0 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EGD97956.1 - 1.8e-14 53.5 1.1 1.8e-14 53.5 0.8 2.8 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus FUSC PF04632.7 EGD97956.1 - 0.026 12.9 3.8 0.037 12.4 2.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Effector_1 PF04518.7 EGD97956.1 - 0.03 13.3 1.4 0.036 13.0 1.0 1.2 1 0 0 1 1 1 0 Effector from type III secretion system Fusion_gly PF00523.13 EGD97956.1 - 0.063 11.3 1.9 2.5 6.0 0.1 2.2 2 0 0 2 2 2 0 Fusion glycoprotein F0 RHH_1 PF01402.16 EGD97956.1 - 0.18 11.7 2.8 0.35 10.8 0.6 2.4 1 1 1 2 2 2 0 Ribbon-helix-helix protein, copG family ApoLp-III PF07464.6 EGD97956.1 - 0.21 11.5 6.1 1.5 8.7 3.5 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF501 PF04417.7 EGD97956.1 - 2.3 8.0 8.4 2.1 8.1 1.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF501) Histone_HNS PF00816.16 EGD97956.1 - 2.7 8.5 6.7 0.3 11.6 1.4 1.7 2 0 0 2 2 2 0 H-NS histone family zf-C4H2 PF10146.4 EGD97956.1 - 3.3 7.6 6.4 0.91 9.4 1.5 1.8 1 1 1 2 2 2 0 Zinc finger-containing protein TBCA PF02970.11 EGD97956.1 - 3.6 7.7 8.7 1.3 9.1 1.8 2.6 2 1 2 4 4 4 0 Tubulin binding cofactor A DUF349 PF03993.7 EGD97956.1 - 4.4 7.5 8.3 31 4.8 2.4 2.8 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) DUF1542 PF07564.6 EGD97956.1 - 7.9 6.5 9.1 2.9 7.9 3.2 2.5 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1542) DUF2407_C PF13373.1 EGD97957.1 - 2.1e-43 147.5 0.1 3.1e-43 147.0 0.1 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EGD97957.1 - 1.2e-33 115.1 0.0 2e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EGD97957.1 - 0.00055 19.2 0.0 0.00097 18.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EGD97957.1 - 0.032 14.0 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Fe-S_biosyn PF01521.15 EGD97958.1 - 8.2e-11 41.8 0.0 1.7e-09 37.5 0.0 2.7 3 1 1 4 4 4 1 Iron-sulphur cluster biosynthesis 2OG-Fe_Oxy_2 PF10014.4 EGD97959.1 - 7.7e-48 162.4 0.1 9.1e-48 162.2 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase MFS_1 PF07690.11 EGD97960.1 - 3.6e-39 134.4 47.5 3.6e-39 134.4 32.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD97960.1 - 4.5e-14 51.8 13.1 4.5e-14 51.8 9.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter zf-DHHC PF01529.15 EGD97960.1 - 4.4 6.6 5.4 15 4.8 0.2 2.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF1741 PF08427.5 EGD97961.1 - 3.3e-81 272.2 0.9 1.1e-80 270.5 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) MRG PF05712.8 EGD97962.1 - 3e-56 189.4 0.0 4.6e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EGD97962.1 - 4.2e-07 29.5 2.3 4.2e-07 29.5 1.6 1.8 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Cnl2_NKP2 PF09447.5 EGD97963.1 - 5.9e-27 93.1 3.3 1e-26 92.3 2.3 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein ATG16 PF08614.6 EGD97963.1 - 0.0067 16.2 1.4 0.0082 15.9 1.0 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF972 PF06156.8 EGD97963.1 - 0.013 15.8 0.5 3.4 8.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 EGD97963.1 - 0.097 12.4 0.7 0.72 9.6 0.0 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper Ctf8 PF09696.5 EGD97965.1 - 1.7e-37 127.8 0.0 2.2e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Glyoxalase PF00903.20 EGD97966.1 - 6.9e-16 58.3 0.1 3.4e-14 52.9 0.0 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EGD97966.1 - 5.5e-09 35.9 0.0 3.1e-05 23.9 0.0 3.0 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGD97966.1 - 4.6e-07 30.4 0.0 0.0009 19.8 0.0 3.0 2 2 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EGD97966.1 - 8e-05 22.6 0.0 0.4 10.5 0.0 3.2 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EGD97966.1 - 0.00054 19.9 0.0 0.018 14.9 0.0 2.7 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Pectinesterase PF01095.14 EGD97966.1 - 0.077 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase DUF3813 PF12758.2 EGD97966.1 - 0.095 12.8 0.8 0.22 11.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) RabGAP-TBC PF00566.13 EGD97967.1 - 2.8e-50 170.7 0.4 2.8e-50 170.7 0.3 2.9 2 2 0 2 2 2 1 Rab-GTPase-TBC domain Tropomyosin_1 PF12718.2 EGD97967.1 - 5.8 6.7 36.5 0.21 11.4 6.4 3.2 2 1 1 3 3 3 0 Tropomyosin like PPTA PF01239.17 EGD97968.1 - 3.1e-35 118.0 13.6 1.5e-08 33.6 0.3 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat APH PF01636.18 EGD97970.1 - 9.6e-17 61.5 0.5 1.4e-16 60.9 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD97970.1 - 1.5e-05 24.6 0.1 2.3e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGD97970.1 - 0.0065 15.6 0.1 0.32 10.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF1679 PF07914.6 EGD97970.1 - 0.063 11.9 0.1 4.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) WD40 PF00400.27 EGD97971.1 - 3.1e-15 55.3 4.7 1.4e-08 34.2 0.0 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EGD97971.1 - 0.13 11.9 0.3 17 5.0 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Utp12 PF04003.7 EGD97972.1 - 1e-22 80.0 0.9 4.5e-22 78.0 0.3 2.3 3 0 0 3 3 3 1 Dip2/Utp12 Family DUF212 PF02681.9 EGD97972.1 - 0.31 10.7 1.4 0.67 9.6 1.0 1.5 1 0 0 1 1 1 0 Divergent PAP2 family Bromodomain PF00439.20 EGD97974.1 - 6.3e-19 67.6 0.1 2.1e-16 59.6 0.0 2.4 2 0 0 2 2 2 2 Bromodomain zf-CSL PF05207.8 EGD97975.1 - 1e-24 85.7 0.3 1.3e-24 85.4 0.2 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EGD97975.1 - 0.057 13.3 0.1 0.097 12.6 0.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Frataxin_Cyay PF01491.11 EGD97976.1 - 2.9e-20 72.1 0.0 9.7e-20 70.3 0.0 1.7 1 1 0 1 1 1 1 Frataxin-like domain DUF1192 PF06698.6 EGD97976.1 - 0.081 12.7 0.3 0.21 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) AKAP7_NLS PF10469.4 EGD97977.1 - 1.4e-16 60.8 0.0 2.4e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.8 EGD97979.1 - 6.2e-169 562.7 3.3 6.2e-169 562.7 2.3 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 Ribosomal_L30 PF00327.15 EGD97980.1 - 6.3e-14 51.2 0.2 9.5e-14 50.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pyridoxal_deC PF00282.14 EGD97981.1 - 4.1e-15 55.1 0.0 7.7e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 EGD97981.1 - 1.3e-05 24.3 0.1 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGD97981.1 - 3.7e-05 22.6 0.0 0.00021 20.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGD97981.1 - 0.0018 17.2 0.0 0.0038 16.2 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.16 EGD97982.1 - 4.4e-92 308.8 0.0 5e-92 308.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2140 PF09911.4 EGD97983.1 - 0.046 12.9 1.0 0.06 12.5 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF1344 PF07076.6 EGD97983.1 - 0.1 12.1 1.2 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) Hex_IIIa PF02455.11 EGD97983.1 - 0.77 8.3 10.4 0.81 8.3 7.2 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Med3 PF11593.3 EGD97983.1 - 0.95 8.6 8.2 0.42 9.8 4.6 1.3 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal DUF763 PF05559.6 EGD97983.1 - 1.4 7.7 6.7 1.7 7.4 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF4228 PF14009.1 EGD97983.1 - 2.2 8.3 15.2 2.6 8.1 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) CDC45 PF02724.9 EGD97983.1 - 8.7 4.2 13.2 10 3.9 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-H2C2_2 PF13465.1 EGD97984.1 - 5.7e-20 70.5 24.3 3.1e-07 30.3 0.9 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGD97984.1 - 1.8e-19 68.8 27.3 4.3e-05 23.5 1.2 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD97984.1 - 9.9e-12 44.3 31.4 0.0005 20.2 3.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD97984.1 - 0.00041 20.4 14.2 0.2 11.8 0.1 5.1 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGD97984.1 - 0.029 14.2 17.5 1.2 9.1 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 EGD97984.1 - 0.31 11.3 18.8 0.45 10.7 0.2 4.8 5 0 0 5 5 5 0 Zinc-finger of C2H2 type XPA_N PF01286.13 EGD97984.1 - 1.2 8.8 10.3 0.12 12.0 0.3 2.9 4 0 0 4 4 4 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 EGD97984.1 - 1.3 9.0 10.2 34 4.5 0.1 3.8 3 1 0 3 3 3 0 Zinc ribbon domain DUF2072 PF09845.4 EGD97984.1 - 1.3 8.9 3.7 0.54 10.1 0.7 1.7 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) Methyltransf_23 PF13489.1 EGD97985.1 - 1.3e-19 70.4 0.0 1.9e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD97985.1 - 5.1e-13 49.3 0.0 9.2e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD97985.1 - 7.7e-12 45.5 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD97985.1 - 2.2e-10 41.1 0.0 3.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD97985.1 - 6e-10 38.9 0.0 8.9e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD97985.1 - 7.2e-08 32.7 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD97985.1 - 2.2e-07 30.9 0.0 4.2e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGD97985.1 - 0.00087 18.4 0.0 0.18 10.8 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 EGD97985.1 - 0.08 13.7 0.0 0.15 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Prp18 PF02840.10 EGD97985.1 - 0.083 12.7 0.2 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Prp18 domain Milton PF12448.3 EGD97985.1 - 0.16 12.1 5.2 0.29 11.3 3.6 1.4 1 1 0 1 1 1 0 Kinesin associated protein Mito_fiss_reg PF05308.6 EGD97985.1 - 1.6 8.0 8.6 2.5 7.3 6.0 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator E1-E2_ATPase PF00122.15 EGD97988.1 - 8.7e-67 224.5 2.9 1.6e-66 223.6 2.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD97988.1 - 7.8e-33 113.5 3.6 7.8e-33 113.5 2.5 2.3 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD97988.1 - 3.6e-28 99.4 0.0 1.9e-27 97.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD97988.1 - 5e-24 84.0 0.0 1.1e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGD97988.1 - 1.2e-13 50.2 0.1 2.9e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGD97988.1 - 3.6e-12 46.8 0.0 2.2e-11 44.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD97988.1 - 1.6e-05 24.5 0.8 0.0011 18.6 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase BRAP2 PF07576.7 EGD97989.1 - 8.4e-25 86.4 0.0 1.5e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EGD97989.1 - 5.1e-20 71.3 4.0 1.5e-19 69.8 2.8 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EGD97989.1 - 2e-09 37.1 10.0 2e-09 37.1 6.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EGD97989.1 - 7.4e-05 22.3 7.2 7.4e-05 22.3 5.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD97989.1 - 0.00049 19.6 7.7 0.00049 19.6 5.3 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD97989.1 - 0.00079 19.0 5.7 0.00079 19.0 3.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD97989.1 - 0.0011 18.9 9.0 0.0011 18.9 6.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGD97989.1 - 0.0022 17.6 3.9 0.007 16.0 1.5 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGD97989.1 - 0.0023 18.0 5.2 0.0023 18.0 3.6 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGD97989.1 - 0.0077 16.0 5.3 0.019 14.7 3.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 EGD97989.1 - 0.063 13.1 2.9 0.19 11.5 2.0 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain CCDC155 PF14662.1 EGD97989.1 - 0.098 12.2 12.6 0.21 11.1 8.8 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Exonuc_VII_L PF02601.10 EGD97989.1 - 0.2 10.8 7.6 0.37 9.9 5.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.3 EGD97989.1 - 0.21 8.8 12.0 0.37 8.0 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HALZ PF02183.13 EGD97989.1 - 0.29 10.8 2.5 2.1 8.1 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-RING_6 PF14835.1 EGD97989.1 - 0.29 10.9 10.4 0.047 13.4 3.5 2.3 1 1 1 2 2 2 0 zf-RING of BARD1-type protein TLE_N PF03920.10 EGD97989.1 - 0.3 10.9 3.6 0.46 10.2 2.0 1.6 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain ApoO PF09769.4 EGD97989.1 - 0.4 10.3 2.2 0.34 10.5 0.1 1.9 2 0 0 2 2 2 0 Apolipoprotein O Prok-RING_4 PF14447.1 EGD97989.1 - 0.41 10.2 6.0 7.2 6.2 2.1 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF4200 PF13863.1 EGD97989.1 - 0.56 10.1 17.2 1.3 8.9 3.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 EGD97989.1 - 0.74 9.5 18.7 0.26 11.0 11.1 1.6 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein zf-RING_4 PF14570.1 EGD97989.1 - 1.4 8.5 6.2 3.7 7.1 4.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF904 PF06005.7 EGD97989.1 - 2 8.7 7.7 0.45 10.8 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF3449 PF11931.3 EGD97989.1 - 2.2 7.7 9.3 0.59 9.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) DUF1993 PF09351.5 EGD97989.1 - 2.4 8.0 7.4 1.9 8.3 1.8 2.7 3 1 1 4 4 3 0 Domain of unknown function (DUF1993) V_ATPase_I PF01496.14 EGD97989.1 - 6.7 4.4 7.5 11 3.7 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EGD97989.1 - 9 5.2 13.7 15 4.5 9.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 APH PF01636.18 EGD97990.1 - 2.1e-16 60.4 0.0 6.1e-16 58.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD97990.1 - 0.0013 18.3 0.2 0.0031 17.1 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGD97990.1 - 0.0085 15.2 0.0 0.019 14.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain DASH_Duo1 PF08651.5 EGD97991.1 - 0.015 14.8 1.6 0.026 14.0 0.3 1.8 1 1 1 2 2 2 0 DASH complex subunit Duo1 Vps23_core PF09454.5 EGD97991.1 - 0.063 12.9 2.9 0.17 11.5 0.3 2.3 2 1 0 2 2 2 0 Vps23 core domain ubiquitin PF00240.18 EGD97992.1 - 1.3e-102 335.2 16.4 6.6e-34 115.1 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EGD97992.1 - 6.7e-59 195.5 15.0 3.3e-19 68.3 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGD97992.1 - 1.1e-18 67.2 7.1 9.6e-05 22.5 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGD97992.1 - 3e-16 59.5 0.5 0.00072 19.2 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing DUF2407 PF10302.4 EGD97992.1 - 9e-11 41.8 0.8 0.066 13.4 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGD97992.1 - 9.8e-11 41.5 1.5 0.081 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EGD97992.1 - 6.9e-08 32.4 0.0 1 9.4 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EGD97992.1 - 5.7e-05 22.7 2.5 4.5 7.0 0.0 3.3 3 0 0 3 3 3 3 FlgD Ig-like domain TUG-UBL1 PF11470.3 EGD97992.1 - 0.00017 21.4 3.3 4.8 7.1 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 EGD97992.1 - 0.00017 21.2 0.7 7.7 6.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) Methyltrans_RNA PF04452.9 EGD97992.1 - 0.00039 19.5 0.2 0.83 8.7 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase IGR PF09597.5 EGD97992.1 - 0.00041 20.1 0.1 16 5.4 0.0 3.3 3 0 0 3 3 3 0 IGR protein motif Big_3_3 PF13750.1 EGD97992.1 - 0.00059 19.2 0.0 12 5.2 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 EGD97992.1 - 0.0048 15.2 8.7 2.4 6.3 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain USP7_C2 PF14533.1 EGD97992.1 - 0.0076 15.6 2.2 14 5.0 0.0 3.0 1 1 1 3 3 3 0 Ubiquitin-specific protease C-terminal ACT_4 PF13291.1 EGD97992.1 - 0.023 15.0 0.4 72 3.8 0.0 3.2 3 0 0 3 3 3 0 ACT domain DUF3861 PF12977.2 EGD97992.1 - 0.027 14.5 3.2 34 4.6 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) Tash_PEST PF07708.6 EGD97992.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif GABP-alpha PF11620.3 EGD97992.1 - 0.042 13.8 3.9 28 4.7 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain EMG1 PF03587.9 EGD97992.1 - 0.059 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase CTDII PF01556.13 EGD97992.1 - 0.067 13.0 10.9 4.1 7.3 0.3 3.5 1 1 2 3 3 3 0 DnaJ C terminal domain Sortase PF04203.8 EGD97992.1 - 0.14 11.7 1.6 23 4.5 0.0 3.0 1 1 2 3 3 3 0 Sortase family FERM_N PF09379.5 EGD97992.1 - 0.39 10.8 9.5 37 4.4 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 EGD97992.1 - 0.55 10.2 3.9 82 3.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) Zn_clus PF00172.13 EGD97993.1 - 0.0037 17.1 7.8 0.0083 16.0 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BMRF2 PF04633.7 EGD97993.1 - 0.33 9.8 0.7 2 7.3 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus BMRF2 protein CAF-1_p150 PF11600.3 EGD97993.1 - 1.7 7.9 5.7 3.8 6.8 3.9 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BAF1_ABF1 PF04684.8 EGD97993.1 - 8.7 5.0 27.6 1 8.1 7.4 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Prenyltrans PF00432.16 EGD97994.1 - 1.6e-32 110.7 37.3 8.6e-13 47.6 0.8 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGD97994.1 - 2.1e-25 89.2 1.1 4.7e-12 46.3 0.1 4.2 2 2 1 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGD97994.1 - 1.3e-05 25.2 0.5 0.31 11.0 0.1 4.0 3 2 0 3 3 3 2 Prenyltransferase-like BLVR PF06375.6 EGD97994.1 - 1.2 8.9 8.7 2 8.2 6.0 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RNase_H2-Ydr279 PF09468.5 EGD97994.1 - 4 6.5 10.4 5.6 6.0 7.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3464 PF11947.3 EGD97994.1 - 4.5 6.7 6.0 7.1 6.0 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Peptidase_S49_N PF08496.5 EGD97994.1 - 8.6 6.1 7.8 14 5.4 5.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal dsrm PF00035.20 EGD97995.1 - 4.8e-06 27.0 0.0 8.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EGD97995.1 - 0.00041 20.5 0.0 0.00068 19.8 0.0 1.3 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 DUF3246 PF11596.3 EGD97997.1 - 2.3 7.4 6.8 2.8 7.1 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Transglycosylas PF06737.9 EGD97998.1 - 0.043 14.1 0.0 0.05 13.9 0.0 1.1 1 0 0 1 1 1 0 Transglycosylase-like domain DUF4448 PF14610.1 EGD98000.1 - 5.9e-41 140.0 0.0 9.8e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1049 PF06305.6 EGD98000.1 - 0.079 12.4 0.5 0.17 11.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Alpha_GJ PF03229.8 EGD98000.1 - 1.4 9.2 15.4 4.4 7.6 8.2 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J Hpt PF01627.18 EGD98001.1 - 5.1e-15 55.2 0.0 8e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Opi1 PF08618.5 EGD98001.1 - 0.002 17.1 0.0 0.002 17.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Opi1 APH PF01636.18 EGD98003.1 - 3.2e-16 59.7 0.0 4.4e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD98003.1 - 0.00023 20.8 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EGD98003.1 - 0.006 15.2 0.0 0.0092 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) HMGL-like PF00682.14 EGD98004.1 - 5.7e-71 238.9 0.3 8.5e-71 238.3 0.2 1.3 1 0 0 1 1 1 1 HMGL-like PTH2 PF01981.11 EGD98006.1 - 1.5e-42 143.9 0.0 1.9e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 BSP_II PF05432.6 EGD98006.1 - 0.00091 18.5 2.3 0.0013 18.0 1.6 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.14 EGD98006.1 - 0.0038 17.5 1.1 0.0061 16.9 0.7 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_ner PF04546.8 EGD98006.1 - 0.015 14.8 1.4 0.02 14.5 1.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PP_M1 PF03012.9 EGD98006.1 - 0.045 13.0 0.1 0.059 12.7 0.1 1.1 1 0 0 1 1 1 0 Phosphoprotein Nop14 PF04147.7 EGD98006.1 - 0.066 11.1 3.6 0.075 10.9 2.5 1.0 1 0 0 1 1 1 0 Nop14-like family Sec23_trunk PF04811.10 EGD98006.1 - 0.098 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain PBP1_TM PF14812.1 EGD98006.1 - 0.12 12.7 5.1 0.21 11.9 3.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3245 PF11595.3 EGD98006.1 - 0.19 11.9 3.2 0.8 9.9 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Nucleoplasmin PF03066.10 EGD98006.1 - 0.21 11.0 10.5 0.35 10.3 7.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EGD98006.1 - 0.24 11.6 11.3 0.41 10.9 7.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EGD98006.1 - 0.68 9.1 6.1 1 8.5 4.2 1.2 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 EGD98006.1 - 0.77 8.8 4.5 1 8.4 3.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 EGD98006.1 - 0.93 7.9 6.1 1.2 7.5 4.2 1.1 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 EGD98006.1 - 3.7 7.3 11.5 4.9 6.9 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 EGD98006.1 - 6.8 5.3 12.0 9 4.8 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Spt5_N PF11942.3 EGD98006.1 - 7 7.3 16.6 12 6.6 11.5 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SART-1 PF03343.8 EGD98007.1 - 5.1e-143 477.6 47.7 6.1e-143 477.3 33.0 1.0 1 0 0 1 1 1 1 SART-1 family FeoC PF09012.5 EGD98007.1 - 0.028 14.1 1.1 8.8 6.1 0.0 3.0 3 0 0 3 3 3 0 FeoC like transcriptional regulator WD40 PF00400.27 EGD98008.1 - 2.7e-22 77.7 0.8 2.5e-06 27.1 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGD98008.1 - 0.0017 17.1 0.0 0.69 8.5 0.0 2.2 1 1 0 2 2 2 2 Nup133 N terminal like ELL PF10390.4 EGD98009.1 - 7.2e-06 25.4 0.0 7.2e-06 25.4 0.0 3.6 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.8 EGD98009.1 - 0.13 13.0 4.2 0.059 14.1 0.8 2.0 2 0 0 2 2 2 0 Occludin homology domain APH PF01636.18 EGD98010.1 - 5.3e-11 42.7 1.8 4.6e-10 39.6 1.2 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF155 PF02582.9 EGD98011.1 - 1e-57 194.8 0.0 2e-57 193.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Aldedh PF00171.17 EGD98012.1 - 6.2e-143 476.4 0.2 7.3e-143 476.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGD98012.1 - 0.13 11.5 0.1 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Pkinase PF00069.20 EGD98014.1 - 6.8e-26 90.9 0.0 9.1e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98014.1 - 1.2e-11 44.1 0.0 1.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1049 PF06305.6 EGD98015.1 - 0.014 14.8 0.4 0.033 13.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF2681 PF10883.3 EGD98015.1 - 0.046 13.9 0.1 0.093 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF2543 PF10820.3 EGD98015.1 - 0.096 12.7 0.8 0.18 11.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) YL1 PF05764.8 EGD98017.1 - 6.4e-58 196.1 25.7 6.4e-58 196.1 17.8 2.2 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 EGD98017.1 - 3.7e-12 45.5 0.2 5.9e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ecl1 PF12855.2 EGD98018.1 - 2.2e-12 46.0 8.0 3.3e-12 45.5 5.5 1.3 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EGD98018.1 - 0.58 10.0 7.2 0.97 9.3 5.0 1.3 1 0 0 1 1 1 0 MYND finger DUF2256 PF10013.4 EGD98018.1 - 4.2 7.1 7.4 0.39 10.5 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) tRNA-synt_2 PF00152.15 EGD98019.1 - 1.6e-74 250.6 0.0 2.7e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGD98019.1 - 1.4e-08 34.4 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Rep_fac-A_3 PF08661.6 EGD98019.1 - 0.1 12.4 0.0 0.54 10.1 0.0 2.2 2 1 0 2 2 2 0 Replication factor A protein 3 PUF PF00806.14 EGD98021.1 - 8e-29 97.4 0.0 1.2e-05 24.4 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EGD98021.1 - 2.9e-11 42.8 0.0 6e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD98021.1 - 2.8e-07 30.2 0.0 6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD98021.1 - 5.7e-07 29.4 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MT-A70 PF05063.9 EGD98022.1 - 1.3e-24 86.6 0.1 1.9e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 MT-A70 Spore_YunB PF09560.5 EGD98022.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein YunB (Spo_YunB) Methyltransf_26 PF13659.1 EGD98022.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C12 PF01088.16 EGD98023.1 - 1.5e-62 210.5 0.0 1.7e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Acyl_transf_1 PF00698.16 EGD98024.1 - 1.2e-79 267.9 0.7 2e-79 267.1 0.5 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EGD98024.1 - 2.7e-78 262.9 0.1 2.7e-78 262.9 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EGD98024.1 - 2.5e-58 196.7 0.1 8.3e-58 195.0 0.1 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGD98024.1 - 4.7e-48 163.2 0.1 4.7e-48 163.2 0.1 2.7 3 0 0 3 3 2 1 short chain dehydrogenase PS-DH PF14765.1 EGD98024.1 - 9.2e-48 162.9 2.1 1.9e-47 161.8 1.5 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EGD98024.1 - 4.1e-34 116.9 0.1 1.6e-33 115.0 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EGD98024.1 - 2.5e-23 82.0 0.8 2.5e-22 78.8 0.4 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thioesterase PF00975.15 EGD98024.1 - 4.8e-22 79.3 0.0 1e-21 78.2 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EGD98024.1 - 2.8e-11 43.7 0.2 2.8e-11 43.7 0.2 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family ADH_zinc_N_2 PF13602.1 EGD98024.1 - 1.6e-09 38.7 0.0 9e-09 36.2 0.0 2.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_5 PF12695.2 EGD98024.1 - 2e-07 30.8 0.0 2.1e-05 24.3 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family ADH_N PF08240.7 EGD98024.1 - 1.1e-06 28.4 0.1 2.6e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 EGD98024.1 - 3.1e-06 26.8 0.8 5.4e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGD98024.1 - 9.6e-05 22.5 0.0 0.00025 21.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGD98024.1 - 0.00032 19.7 0.2 0.00081 18.4 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 EGD98024.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGD98024.1 - 0.0027 17.7 3.3 0.34 10.9 0.1 3.0 2 1 0 2 2 2 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 EGD98024.1 - 0.0041 16.7 0.5 0.0095 15.5 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EGD98024.1 - 0.084 13.2 0.9 1.8 9.0 0.0 3.1 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase PGAP1 PF07819.8 EGD98024.1 - 0.093 12.3 0.0 0.36 10.3 0.0 2.0 1 0 0 1 1 1 0 PGAP1-like protein Phage_CII PF05269.6 EGD98024.1 - 0.17 11.9 0.0 0.59 10.1 0.0 1.9 2 0 0 2 2 1 0 Bacteriophage CII protein DcpS_C PF11969.3 EGD98025.1 - 1.8e-30 105.5 0.3 2.7e-30 104.9 0.2 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EGD98025.1 - 7.7e-29 100.3 0.0 1.3e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Alk_phosphatase PF00245.15 EGD98026.1 - 2.8e-57 194.3 0.2 4e-56 190.4 0.1 2.2 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EGD98026.1 - 6.6e-08 32.0 1.5 1.7e-07 30.7 0.3 2.0 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EGD98026.1 - 0.0001 21.7 0.1 0.00022 20.6 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EGD98026.1 - 0.00093 17.7 0.1 0.002 16.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) FTA4 PF13093.1 EGD98026.1 - 0.0066 15.9 0.1 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GPAT_N PF14829.1 EGD98026.1 - 0.021 14.4 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal RNase_H2_suC PF08615.6 EGD98027.1 - 5.1e-28 97.6 0.2 7.7e-28 97.0 0.0 1.4 2 0 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Peptidase_S24 PF00717.18 EGD98027.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase S24-like RNase_T PF00929.19 EGD98028.1 - 9.3e-28 97.5 0.0 1.6e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EGD98028.1 - 0.14 11.6 0.0 0.31 10.4 0.0 1.7 1 1 0 1 1 1 0 3'-5' exonuclease Nop53 PF07767.6 EGD98029.1 - 6.4e-110 367.7 37.6 9.2e-110 367.2 26.0 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Myb_Cef PF11831.3 EGD98030.1 - 8.7e-58 195.2 3.4 8.7e-58 195.2 2.3 3.5 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EGD98030.1 - 5.6e-20 71.1 3.8 4.2e-09 36.3 0.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD98030.1 - 2.1e-19 69.3 6.0 7.9e-13 48.3 1.1 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain MOZ_SAS PF01853.13 EGD98031.1 - 9.8e-84 279.2 0.0 1.4e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EGD98031.1 - 1.2e-23 82.5 0.0 2.7e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF1918 PF08940.6 EGD98031.1 - 0.018 14.3 0.0 0.073 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) CD24 PF14984.1 EGD98031.1 - 0.18 11.6 0.2 0.39 10.5 0.1 1.5 1 0 0 1 1 1 0 CD24 protein Orthopox_C10L PF07020.6 EGD98032.1 - 0.17 12.4 8.5 2.1 8.9 0.2 3.5 3 0 0 3 3 3 0 Orthopoxvirus C10L protein F1F0-ATPsyn_F PF10791.4 EGD98033.1 - 1.1e-37 128.1 0.2 1.2e-37 127.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EGD98033.1 - 0.0024 17.8 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.7 EGD98034.1 - 1.1e-35 121.5 1.5 1.6e-35 120.9 1.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Nipped-B_C PF12830.2 EGD98035.1 - 1.1e-52 178.4 9.1 1.4e-51 174.7 0.7 3.9 3 1 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EGD98035.1 - 2.8e-11 43.1 6.0 8.2e-11 41.6 1.5 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EGD98035.1 - 4.5e-05 23.1 1.0 0.26 11.4 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EGD98035.1 - 0.0082 16.0 4.9 0.22 11.3 0.3 3.8 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EGD98035.1 - 0.083 13.2 0.4 1.4 9.3 0.1 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EGD98035.1 - 0.2 9.9 10.4 0.45 8.7 4.2 3.4 3 1 0 3 3 3 0 Adaptin N terminal region Methyltransf_11 PF08241.7 EGD98036.1 - 4.3e-07 30.3 0.0 7.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD98036.1 - 0.00013 21.1 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGD98036.1 - 0.0032 17.7 0.0 0.009 16.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD98036.1 - 0.017 14.7 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain TFIIS_C PF01096.13 EGD98037.1 - 4.9e-15 54.8 2.1 4.9e-15 54.8 1.4 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGD98037.1 - 3.1e-06 26.7 0.5 3.1e-06 26.7 0.3 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Ribosomal_S27e PF01667.12 EGD98037.1 - 0.015 14.7 4.5 1.7 8.2 0.0 3.3 2 1 1 3 3 3 0 Ribosomal protein S27 RRN7 PF11781.3 EGD98037.1 - 0.025 14.0 7.6 1.1 8.8 0.1 4.0 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 RecR PF02132.10 EGD98037.1 - 0.038 13.4 1.1 0.038 13.4 0.8 2.0 2 0 0 2 2 2 0 RecR protein tRNA-synt_1f PF01921.13 EGD98037.1 - 0.041 12.5 0.2 0.06 12.0 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF2072 PF09845.4 EGD98037.1 - 0.056 13.3 1.8 1.5 8.7 0.0 2.2 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) Mu-like_Com PF10122.4 EGD98037.1 - 0.074 12.1 1.3 0.16 11.0 0.1 2.0 2 0 0 2 2 2 0 Mu-like prophage protein Com zinc_ribbon_2 PF13240.1 EGD98037.1 - 0.076 12.5 8.9 9.3 5.8 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGD98037.1 - 0.09 12.0 7.6 2.1 7.6 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Lar_restr_allev PF14354.1 EGD98037.1 - 0.097 12.9 6.9 0.56 10.5 0.5 3.1 1 1 2 3 3 3 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EGD98037.1 - 0.11 12.3 3.1 2.1 8.2 1.2 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 EGD98037.1 - 0.13 12.2 3.1 1.4 8.9 0.1 2.6 2 1 0 2 2 2 0 zinc-finger Rubredoxin PF00301.15 EGD98037.1 - 0.25 11.2 2.1 58 3.6 0.1 3.2 2 1 1 3 3 3 0 Rubredoxin Auto_anti-p27 PF06677.7 EGD98037.1 - 0.27 11.0 2.2 14 5.5 0.0 3.1 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NMD3 PF04981.8 EGD98037.1 - 0.33 10.0 4.0 1.7 7.7 2.7 2.0 1 1 0 1 1 1 0 NMD3 family zf-C4_Topoisom PF01396.14 EGD98037.1 - 0.38 10.3 4.6 1.3 8.5 0.2 3.1 2 2 1 3 3 3 0 Topoisomerase DNA binding C4 zinc finger OrfB_Zn_ribbon PF07282.6 EGD98037.1 - 0.46 10.1 7.4 1.2 8.8 0.2 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain ArfGap PF01412.13 EGD98037.1 - 0.94 9.2 3.4 7.7 6.3 0.0 2.3 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf XPA_N PF01286.13 EGD98037.1 - 1 9.1 4.2 40 4.0 0.0 3.2 3 0 0 3 3 3 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 EGD98037.1 - 1.1 9.2 0.1 1.1 9.2 0.1 3.1 3 1 1 4 4 4 0 Zinc ribbon domain DUF164 PF02591.10 EGD98037.1 - 1.2 9.0 5.1 11 5.9 0.1 3.2 2 1 1 3 3 3 0 Putative zinc ribbon domain IBR PF01485.16 EGD98037.1 - 1.5 8.7 7.0 2.4 8.0 0.1 2.8 2 1 0 2 2 2 0 IBR domain Rpr2 PF04032.11 EGD98037.1 - 1.8 8.4 6.6 0.31 10.9 0.2 2.5 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain NOB1_Zn_bind PF08772.6 EGD98037.1 - 2.4 8.0 6.4 20 5.1 0.1 3.0 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 EGD98037.1 - 3.5 7.5 12.0 0.43 10.4 0.5 2.7 2 1 0 2 2 1 0 Double zinc ribbon zf-IS66 PF13005.2 EGD98037.1 - 3.6 7.6 7.2 4.4 7.3 0.1 3.6 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 Zn_ribbon_recom PF13408.1 EGD98037.1 - 4.4 7.6 9.3 13 6.1 0.6 2.8 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain ADK_lid PF05191.9 EGD98037.1 - 5.6 6.7 7.7 10 5.8 0.3 3.1 3 0 0 3 3 3 0 Adenylate kinase, active site lid Nudix_N_2 PF14803.1 EGD98037.1 - 6.2 6.6 9.8 2 8.1 0.7 3.2 3 1 0 3 3 3 0 Nudix N-terminal zf-C2HC5 PF06221.8 EGD98037.1 - 6.3 6.6 6.8 1.2 8.9 0.2 2.4 3 0 0 3 3 2 0 Putative zinc finger motif, C2HC5-type HEAT_2 PF13646.1 EGD98038.1 - 8e-34 115.7 7.2 4.4e-15 55.7 0.1 3.6 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 EGD98038.1 - 1.6e-18 65.1 1.8 0.0027 18.0 0.0 6.5 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EGD98038.1 - 1.3e-07 31.8 10.8 0.0013 19.1 0.1 5.8 3 2 3 6 6 6 4 HEAT-like repeat HEAT PF02985.17 EGD98038.1 - 0.00013 21.7 4.0 6.7 7.0 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat Pyr_redox_2 PF07992.9 EGD98039.1 - 1.9e-18 67.0 0.0 3.8e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD98039.1 - 9.3e-11 41.9 0.0 1.5e-09 38.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EGD98039.1 - 1.4e-05 23.9 0.1 5.2e-05 22.2 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EGD98039.1 - 0.00018 20.6 0.1 0.00047 19.3 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EGD98039.1 - 0.0002 20.9 0.2 0.0007 19.2 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EGD98039.1 - 0.0015 18.6 0.0 0.0039 17.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Myc_N PF01056.13 EGD98039.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region EF-hand_4 PF12763.2 EGD98039.1 - 0.25 11.0 1.2 2.8 7.7 0.0 2.9 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand CLTH PF10607.4 EGD98040.1 - 5.3e-34 117.0 0.4 7.2e-34 116.5 0.3 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EGD98040.1 - 3e-09 36.3 0.1 6.6e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 LisH PRK PF00485.13 EGD98041.1 - 1.2e-55 188.0 0.0 1.6e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EGD98041.1 - 2.2e-08 34.9 0.0 5.3e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD98041.1 - 7.8e-06 26.2 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD98041.1 - 0.0024 17.0 0.0 0.0043 16.1 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin CPT PF07931.7 EGD98041.1 - 0.0027 17.3 0.0 0.0073 15.9 0.0 1.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein DUF87 PF01935.12 EGD98041.1 - 0.0054 16.5 0.0 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 EGD98041.1 - 0.027 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EGD98041.1 - 0.063 12.7 0.2 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 EGD98041.1 - 0.085 12.7 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGD98041.1 - 0.088 12.7 0.1 0.21 11.5 0.1 1.6 1 1 1 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EGD98041.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter NUC153 PF08159.7 EGD98042.1 - 5e-13 48.3 7.3 4.2e-12 45.4 0.1 3.8 3 0 0 3 3 3 1 NUC153 domain DUF4148 PF13663.1 EGD98042.1 - 0.045 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Npa1 PF11707.3 EGD98043.1 - 6.8e-95 317.8 1.1 1.5e-94 316.7 0.8 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal HA2 PF04408.18 EGD98045.1 - 6.4e-29 99.9 0.1 1.9e-28 98.4 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGD98045.1 - 9e-24 83.5 0.0 5.5e-23 80.9 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGD98045.1 - 3.2e-12 46.1 0.0 9.2e-12 44.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EGD98045.1 - 3.8e-10 39.7 0.9 1.1e-09 38.2 0.6 1.8 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EGD98045.1 - 7.2e-05 22.3 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EGD98045.1 - 0.00029 19.8 0.0 0.0007 18.5 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EGD98045.1 - 0.0081 16.3 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGD98045.1 - 0.012 15.3 0.3 0.068 12.9 0.1 2.2 2 0 0 2 2 2 0 Part of AAA domain RS4NT PF08071.7 EGD98045.1 - 0.08 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 RS4NT (NUC023) domain SUV3_C PF12513.3 EGD98046.1 - 1.1e-15 56.8 0.0 2.2e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EGD98046.1 - 3.5e-09 36.3 0.0 1.9e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TK PF00265.13 EGD98046.1 - 0.13 11.8 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 Thymidine kinase Sec1 PF00995.18 EGD98047.1 - 1.6e-129 433.1 0.0 1.9e-129 432.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.18 EGD98048.1 - 3.1e-08 33.2 0.6 7.5e-08 32.0 0.4 1.7 1 0 0 1 1 1 1 G-patch domain adh_short PF00106.20 EGD98049.1 - 7.8e-14 51.9 0.0 1.6e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD98049.1 - 2.4e-08 33.8 0.0 4.7e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD98049.1 - 0.00025 20.8 0.0 0.00082 19.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGD98049.1 - 0.0028 17.6 0.1 0.0087 16.0 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGD98049.1 - 0.029 13.8 0.1 0.041 13.3 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGD98049.1 - 0.15 11.8 3.9 0.16 11.7 0.2 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4235 PF14019.1 EGD98049.1 - 0.19 11.6 2.0 0.23 11.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) RNase_H2-Ydr279 PF09468.5 EGD98049.1 - 3.3 6.8 12.2 6.2 5.9 8.5 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Epimerase PF01370.16 EGD98050.1 - 1.9e-45 155.1 0.0 2.7e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EGD98050.1 - 4.2e-26 90.6 0.1 7.2e-26 89.9 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EGD98050.1 - 1.3e-15 56.8 0.0 1.9e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGD98050.1 - 3.9e-13 49.6 0.0 5.9e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGD98050.1 - 4.1e-12 45.6 0.0 7e-11 41.5 0.0 2.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGD98050.1 - 4.2e-12 45.5 0.0 6.2e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EGD98050.1 - 9.9e-09 35.1 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGD98050.1 - 1.4e-08 34.9 0.0 2.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGD98050.1 - 1.9e-07 30.2 0.0 5.1e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein DAO PF01266.19 EGD98050.1 - 0.00046 19.1 0.2 0.0017 17.3 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase adh_short_C2 PF13561.1 EGD98050.1 - 0.00047 20.0 0.0 0.00069 19.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_18 PF12847.2 EGD98050.1 - 0.003 18.1 0.0 2.3 8.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain NmrA PF05368.8 EGD98050.1 - 0.0031 16.8 0.0 0.0075 15.5 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EGD98050.1 - 0.0035 16.7 0.1 0.0066 15.8 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EGD98050.1 - 0.0087 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EGD98050.1 - 0.041 14.1 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EGD98050.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 EGD98051.1 - 2.3e-24 86.3 0.0 2.7e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGD98051.1 - 2.1e-10 40.2 0.0 3.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EGD98051.1 - 1.5e-06 27.8 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD98051.1 - 2.4e-05 23.1 0.0 3.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EGD98051.1 - 7.6e-05 21.8 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EGD98051.1 - 0.13 11.1 0.0 4.3 6.1 0.0 2.5 3 0 0 3 3 3 0 Male sterility protein PAT1 PF09770.4 EGD98052.1 - 9.1e-260 864.3 24.9 1e-259 864.1 17.3 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 EGD98053.1 - 9.4e-144 478.3 4.1 1.1e-143 478.1 2.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.20 EGD98054.1 - 2.5e-41 139.8 3.3 3.4e-41 139.4 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UMP1 PF05348.6 EGD98055.1 - 1.5e-23 83.2 0.1 1.7e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DUF3591 PF12157.3 EGD98055.1 - 0.081 11.3 0.1 0.1 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) Rad60-SLD_2 PF13881.1 EGD98056.1 - 1.8e-12 47.1 0.0 4.1e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGD98056.1 - 0.0012 18.9 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EGD98056.1 - 0.0017 17.7 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF3608 PF12257.3 EGD98057.1 - 7.7e-72 241.5 0.0 4.2e-71 239.1 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EGD98057.1 - 2.4e-30 104.0 1.3 4.7e-30 103.1 0.9 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FNIP_N PF14636.1 EGD98058.1 - 6e-28 97.9 0.1 6e-28 97.9 0.1 5.2 4 2 0 5 5 5 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 EGD98058.1 - 0.015 14.8 0.4 0.08 12.5 0.1 2.1 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain C9orf72-like PF15019.1 EGD98058.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 C9orf72-like protein family Helicase_C PF00271.26 EGD98059.1 - 1.3e-06 28.1 0.0 3.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Trypan_PARP PF05887.6 EGD98059.1 - 0.0013 18.5 19.5 0.0024 17.6 13.5 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) zf-C3HC4_3 PF13920.1 EGD98059.1 - 0.012 15.2 13.5 0.012 15.2 9.3 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD98059.1 - 0.057 13.4 19.3 0.049 13.6 8.1 2.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGD98059.1 - 0.19 11.4 7.4 0.43 10.3 5.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 EGD98059.1 - 0.32 10.6 12.1 1.3 8.7 8.5 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PLRV_ORF5 PF01690.12 EGD98059.1 - 1.9 7.5 7.3 2.9 6.9 5.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein zf-RING_5 PF14634.1 EGD98059.1 - 2.5 7.8 20.1 34 4.2 13.9 2.4 1 1 0 1 1 1 0 zinc-RING finger domain Neisseria_TspB PF05616.8 EGD98059.1 - 4.2 5.6 5.3 5.5 5.2 3.7 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein TPR_11 PF13414.1 EGD98060.1 - 3.8e-11 42.4 12.6 1.5e-06 27.7 0.1 4.6 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 EGD98060.1 - 1e-10 40.6 19.8 0.00017 21.2 0.0 6.4 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGD98060.1 - 6.9e-09 36.1 27.6 0.0006 20.4 0.1 6.3 6 1 1 7 7 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGD98060.1 - 1.6e-08 34.3 16.9 0.016 15.1 2.3 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGD98060.1 - 4.9e-08 32.2 9.0 0.00022 20.7 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGD98060.1 - 3.2e-07 29.6 0.4 0.06 13.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGD98060.1 - 1.2e-05 25.5 16.0 0.19 12.0 1.3 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGD98060.1 - 2.1e-05 24.7 18.5 0.12 13.0 0.1 8.3 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD98060.1 - 0.00011 21.7 5.2 0.75 9.7 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGD98060.1 - 0.03 14.7 16.6 6.5 7.4 0.1 6.4 8 0 0 8 8 7 0 Tetratricopeptide repeat Apc3 PF12895.2 EGD98060.1 - 0.043 13.9 5.4 1.7 8.8 0.4 4.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.7 EGD98060.1 - 0.061 12.9 0.0 0.22 11.1 0.0 1.9 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_17 PF13431.1 EGD98060.1 - 0.07 13.3 5.4 61 4.1 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGD98060.1 - 1.6 8.6 18.1 0.78 9.6 0.1 5.6 7 1 0 7 7 7 0 Tetratricopeptide repeat Pmp3 PF01679.12 EGD98061.1 - 1.9e-19 69.0 7.0 2.5e-19 68.6 4.9 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BAF1_ABF1 PF04684.8 EGD98061.1 - 0.89 8.3 14.4 1.2 7.9 10.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Totivirus_coat PF05518.6 EGD98061.1 - 1.7 6.3 7.1 2 6.1 5.0 1.0 1 0 0 1 1 1 0 Totivirus coat protein PAT1 PF09770.4 EGD98061.1 - 4.9 5.2 14.5 5.2 5.1 10.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SH3_9 PF14604.1 EGD98062.1 - 1e-07 31.4 0.2 2.6e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGD98062.1 - 0.00031 20.0 0.1 0.00058 19.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 EGD98062.1 - 0.032 13.5 2.3 0.059 12.6 1.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 EGD98062.1 - 0.07 12.7 0.2 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 EGD98062.1 - 0.072 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 EGD98062.1 - 0.13 11.8 0.1 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 EGD98062.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) DUF3485 PF11984.3 EGD98064.1 - 0.018 14.1 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) CcoS PF03597.10 EGD98064.1 - 0.31 10.5 2.8 0.54 9.7 1.9 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Fungal_trans PF04082.13 EGD98066.1 - 8.8e-23 80.4 0.0 1.9e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD98066.1 - 7e-05 22.6 7.8 0.00015 21.5 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_Ca_ex PF01699.19 EGD98067.1 - 7.7e-42 142.2 37.4 1.8e-22 79.4 7.4 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF4501 PF14946.1 EGD98067.1 - 0.1 12.0 0.0 0.43 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) GHMP_kinases_N PF00288.21 EGD98068.1 - 8.4e-15 54.5 1.1 1.9e-14 53.4 0.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGD98068.1 - 5.8e-07 29.6 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal MCM PF00493.18 EGD98069.1 - 8.8e-132 438.9 0.1 1.3e-131 438.3 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGD98069.1 - 4.7e-17 62.6 0.0 4.7e-17 62.6 0.0 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGD98069.1 - 7.1e-05 22.0 0.0 0.00038 19.6 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGD98069.1 - 0.0043 16.7 0.0 0.014 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGD98069.1 - 0.0087 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGD98069.1 - 0.014 14.9 0.0 0.036 13.5 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain EamA PF00892.15 EGD98070.1 - 7.2e-06 26.0 6.3 7.2e-06 26.0 4.4 1.8 1 1 1 2 2 2 1 EamA-like transporter family DUF914 PF06027.7 EGD98070.1 - 0.0001 21.2 0.1 0.00013 20.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UPF0546 PF10639.4 EGD98070.1 - 0.014 15.1 4.2 0.021 14.6 2.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 EmrE PF13536.1 EGD98070.1 - 0.016 15.4 4.3 0.016 15.4 3.0 1.7 1 1 1 2 2 2 0 Multidrug resistance efflux transporter Voltage_CLC PF00654.15 EGD98071.1 - 6.1e-86 288.6 24.3 6.1e-86 288.6 16.8 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EGD98071.1 - 2.1e-07 30.6 0.0 0.0002 21.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.18 EGD98072.1 - 4.9e-14 52.1 0.7 8.7e-14 51.3 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGD98072.1 - 0.0088 16.1 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 UCR_TM PF02921.9 EGD98073.1 - 1.1e-17 63.9 2.7 2.1e-17 63.0 1.9 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EGD98073.1 - 2.6e-16 58.9 0.0 4.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain She9_MDM33 PF05546.6 EGD98074.1 - 2.8e-93 311.2 10.0 3.7e-93 310.8 6.9 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EGD98074.1 - 0.0081 15.7 1.0 0.018 14.6 0.7 1.5 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein MBD_C PF14048.1 EGD98074.1 - 0.036 14.6 0.4 0.22 12.1 0.0 2.5 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 WHEP-TRS PF00458.15 EGD98074.1 - 0.21 11.2 1.6 3.4 7.4 1.1 2.5 1 1 0 1 1 1 0 WHEP-TRS domain DUF1395 PF07160.7 EGD98074.1 - 0.3 10.5 7.1 0.047 13.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) DUF1110 PF06533.7 EGD98074.1 - 4.4 7.0 6.4 1.4 8.7 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1110) Aminotran_1_2 PF00155.16 EGD98075.1 - 7.1e-40 137.0 0.0 8.2e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD98075.1 - 0.00076 18.7 0.0 0.0018 17.4 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_3 PF00202.16 EGD98075.1 - 0.019 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III RabGAP-TBC PF00566.13 EGD98075.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Zn_clus PF00172.13 EGD98076.1 - 1.8e-16 59.7 30.3 3.1e-08 33.4 7.1 2.7 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGD98076.1 - 2.6e-14 52.7 1.7 2.6e-14 52.7 1.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain PNPOx_C PF10590.4 EGD98077.1 - 8.2e-22 76.4 3.1 5.3e-21 73.8 1.4 2.4 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EGD98077.1 - 1e-10 41.4 0.0 6.5e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EGD98077.1 - 0.0044 17.2 0.1 0.042 14.1 0.1 2.2 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PPR_2 PF13041.1 EGD98078.1 - 1.2e-40 137.1 11.9 2.2e-09 37.1 0.0 13.5 11 3 2 14 14 14 9 PPR repeat family PPR_3 PF13812.1 EGD98078.1 - 7.6e-29 97.5 20.0 4.7e-05 23.3 0.0 14.1 15 0 0 15 15 15 6 Pentatricopeptide repeat domain PPR PF01535.15 EGD98078.1 - 1.1e-24 84.6 12.6 0.00041 20.1 0.0 13.2 14 0 0 14 14 14 5 PPR repeat PPR_1 PF12854.2 EGD98078.1 - 1.3e-17 62.9 0.9 7.2e-07 28.5 0.0 9.1 11 0 0 11 11 11 3 PPR repeat RPM2 PF08579.6 EGD98078.1 - 2.4e-08 34.1 0.4 2.7e-06 27.5 0.0 3.7 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 EGD98078.1 - 0.0012 17.7 0.1 1.6 7.5 0.0 3.4 3 0 0 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway F-box PF00646.28 EGD98079.1 - 2.3e-05 23.9 0.3 5.8e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD98079.1 - 0.0003 20.4 0.8 0.00066 19.3 0.5 1.6 1 0 0 1 1 1 1 F-box-like Peptidase_S41 PF03572.13 EGD98080.1 - 6.3e-12 45.2 0.0 1.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 Ribosomal_L7Ae PF01248.21 EGD98081.1 - 4.3e-17 61.4 0.1 1.1e-16 60.1 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EGD98081.1 - 0.004 17.0 0.4 0.012 15.4 0.3 1.8 1 1 0 1 1 1 1 RNase P subunit Pop3 DUF221 PF02714.10 EGD98082.1 - 4.4e-113 377.4 23.5 9.3e-113 376.3 10.6 2.7 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGD98082.1 - 2.6e-43 147.2 1.4 2.6e-43 147.2 1.0 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EGD98082.1 - 3.6e-28 97.2 0.0 7.1e-28 96.3 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EGD98082.1 - 1e-20 74.0 0.0 2.2e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EGD98082.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) EHN PF06441.7 EGD98085.1 - 2.9e-36 123.7 2.9 1.7e-35 121.3 0.2 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EGD98085.1 - 8.7e-16 58.4 2.5 3.5e-15 56.5 1.7 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD98085.1 - 2.3e-13 50.2 0.0 1.4e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold RSN1_TM PF13967.1 EGD98087.1 - 0.017 14.6 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport tRNA_NucTran2_2 PF13735.1 EGD98088.1 - 0.013 15.2 0.5 0.023 14.5 0.3 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative DUF2849 PF11011.3 EGD98088.1 - 0.25 11.6 2.2 0.72 10.1 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) Pyridox_oxase_2 PF12766.2 EGD98090.1 - 1.7e-23 82.8 0.0 2.9e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase LRR_9 PF14580.1 EGD98091.1 - 1.2e-50 171.4 0.3 1.8e-50 170.9 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EGD98091.1 - 1.5e-10 40.4 9.7 8.3e-05 22.1 0.4 3.9 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD98091.1 - 4.1e-08 32.8 10.3 3.4e-07 29.9 1.6 3.3 1 1 2 3 3 3 1 Leucine rich repeat HTH_38 PF13936.1 EGD98091.1 - 0.0034 16.9 0.4 0.0069 15.9 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain LRR_1 PF00560.28 EGD98091.1 - 0.0048 16.7 6.5 13 6.3 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich Repeat UPF0128 PF03673.8 EGD98091.1 - 0.069 12.4 0.5 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) LRR_7 PF13504.1 EGD98091.1 - 0.12 12.6 4.9 66 4.3 0.0 4.5 4 1 0 4 4 4 0 Leucine rich repeat GDA1_CD39 PF01150.12 EGD98092.1 - 6e-109 364.4 0.0 8e-109 364.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Acyltransferase PF01553.16 EGD98093.1 - 8.5e-16 57.5 0.0 2.1e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase PSD1 PF07587.6 EGD98093.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) Pantoate_ligase PF02569.10 EGD98094.1 - 7.9e-83 277.4 0.0 1.9e-82 276.1 0.0 1.6 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Glyco_hydro_100 PF12899.2 EGD98094.1 - 0.046 12.1 0.0 0.06 11.7 0.0 1.1 1 0 0 1 1 1 0 Alkaline and neutral invertase DEAD PF00270.24 EGD98095.1 - 1.9e-38 131.6 0.2 4.5e-38 130.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD98095.1 - 6.8e-20 70.7 0.0 2.2e-19 69.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EGD98095.1 - 7e-19 67.1 0.0 1.5e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EGD98095.1 - 0.0012 18.7 0.3 0.008 16.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit WD40 PF00400.27 EGD98096.1 - 6.8e-24 82.8 5.7 1.8e-05 24.3 0.2 6.4 7 1 0 7 7 7 5 WD domain, G-beta repeat DUF3423 PF11903.3 EGD98096.1 - 0.055 13.2 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3423) Fungal_trans_2 PF11951.3 EGD98097.1 - 9.4e-10 37.6 4.1 2.2e-08 33.1 0.2 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD98097.1 - 7.5e-06 25.7 10.1 1.9e-05 24.4 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 EGD98097.1 - 0.8 8.4 13.6 1.3 7.8 9.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MFS_1 PF07690.11 EGD98098.1 - 5.4e-44 150.3 56.6 5.1e-43 147.1 38.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD98098.1 - 9.5e-11 40.9 37.7 1.6e-07 30.2 14.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EGD98098.1 - 1.1e-05 23.9 23.0 1.6e-05 23.3 16.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GATase PF00117.23 EGD98099.1 - 3.2e-13 49.5 0.0 4.2e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGD98099.1 - 0.022 14.1 0.3 0.091 12.1 0.2 2.0 1 1 0 1 1 1 0 Peptidase C26 GATase_3 PF07685.9 EGD98099.1 - 0.044 13.3 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF775 PF05603.7 EGD98100.1 - 1.2e-62 210.9 0.0 1.4e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 EGD98101.1 - 1.1e-08 34.7 0.0 2.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain FlgM PF04316.8 EGD98101.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF1573 PF07610.6 EGD98101.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) RNA_pol_Rpb8 PF03870.10 EGD98102.1 - 3.4e-37 127.7 0.0 3.8e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 EGD98103.1 - 4e-122 407.5 0.0 4.4e-122 407.4 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 EGD98105.1 - 1.5e-15 56.7 0.0 2.9e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain MAT1 PF06391.8 EGD98105.1 - 0.0056 16.2 2.0 0.0077 15.8 1.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 NMU PF02070.10 EGD98105.1 - 0.025 14.0 0.5 0.96 9.0 0.0 2.4 2 0 0 2 2 2 0 Neuromedin U UPF0086 PF01868.11 EGD98106.1 - 1.1e-28 98.7 0.1 1.8e-28 97.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Copper-bind PF00127.15 EGD98107.1 - 0.01 16.0 0.1 0.029 14.5 0.1 1.7 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family DUF1325 PF07039.6 EGD98107.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 SGF29 tudor-like domain DUF605 PF04652.11 EGD98107.1 - 0.32 10.3 7.3 0.41 9.9 5.1 1.1 1 0 0 1 1 1 0 Vta1 like Tmemb_cc2 PF10267.4 EGD98107.1 - 3.5 6.1 5.7 4.2 5.8 3.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Ank_2 PF12796.2 EGD98108.1 - 1.2e-61 205.0 8.0 5.9e-13 48.9 0.0 6.2 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD98108.1 - 8.8e-45 150.3 10.6 8.5e-09 35.7 0.0 8.8 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD98108.1 - 4.9e-42 141.0 6.2 3.7e-10 39.7 0.0 6.1 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 EGD98108.1 - 7.2e-36 120.2 3.1 0.00026 20.6 0.0 10.5 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.1 EGD98108.1 - 1.1e-21 74.7 1.4 0.00039 20.3 0.0 9.5 11 0 0 11 11 11 3 Ankyrin repeat Trehalase_Ca-bi PF07492.6 EGD98108.1 - 1.9e-05 23.8 4.7 5.9 6.3 0.1 5.8 6 0 0 6 6 6 1 Neutral trehalase Ca2+ binding domain YscJ_FliF PF01514.12 EGD98108.1 - 0.041 13.0 0.3 0.94 8.5 0.0 3.1 3 1 1 4 4 4 0 Secretory protein of YscJ/FliF family MFS_1 PF07690.11 EGD98109.1 - 4.1e-28 98.1 29.6 6.5e-28 97.4 20.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FYVE_2 PF02318.11 EGD98111.1 - 0.0096 15.8 23.3 0.4 10.5 2.9 3.3 3 0 0 3 3 3 3 FYVE-type zinc finger zf-C3HC4 PF00097.20 EGD98111.1 - 0.019 14.6 38.3 0.26 10.9 5.4 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Siva PF05458.7 EGD98111.1 - 4 6.9 22.3 0.32 10.5 2.6 3.3 3 0 0 3 3 3 0 Cd27 binding protein (Siva) BAF1_ABF1 PF04684.8 EGD98111.1 - 5.5 5.7 8.5 8.5 5.0 5.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Cofilin_ADF PF00241.15 EGD98114.1 - 8.1e-10 38.6 0.0 1e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.19 EGD98115.1 - 4.2e-36 123.4 0.0 7.9e-36 122.6 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 EGD98116.1 - 1.9e-59 199.6 0.1 2.2e-59 199.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD98116.1 - 1.8e-18 67.1 0.0 2.6e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD98116.1 - 1.9e-07 30.5 0.0 2.1e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGD98116.1 - 1.6e-06 27.7 0.1 7.7e-06 25.4 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGD98116.1 - 0.00086 18.6 0.0 0.0014 17.8 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EGD98116.1 - 0.0023 17.8 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2075 PF09848.4 EGD98116.1 - 0.051 12.5 0.1 1.5 7.7 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 EGD98116.1 - 0.051 12.7 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 EGD98116.1 - 0.054 12.6 0.2 0.074 12.1 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 EGD98116.1 - 0.11 11.9 0.9 1.2 8.5 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 EGD98116.1 - 0.39 10.2 1.6 4.4 6.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein adh_short PF00106.20 EGD98117.1 - 6.8e-34 117.1 0.0 1.1e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD98117.1 - 1.4e-16 60.9 0.0 1.9e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD98117.1 - 3.6e-13 49.5 0.0 5.5e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EGD98117.1 - 5.3e-05 22.9 0.1 0.00014 21.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EGD98117.1 - 0.0021 17.0 0.1 0.0055 15.6 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGD98117.1 - 0.0026 17.2 0.1 0.0051 16.2 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Lin0512_fam PF09585.5 EGD98117.1 - 0.018 14.5 0.2 0.3 10.6 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) DUF1776 PF08643.5 EGD98117.1 - 0.085 11.9 0.0 0.18 10.9 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) GATA PF00320.22 EGD98119.1 - 4.7e-30 102.6 18.1 4.8e-16 57.8 3.5 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EGD98119.1 - 1.2e-07 30.9 3.0 0.0033 16.7 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 EGD98119.1 - 0.0038 17.1 1.6 0.49 10.3 0.1 2.7 2 0 0 2 2 2 1 Zinc ribbon domain DZR PF12773.2 EGD98119.1 - 0.016 15.0 11.8 0.15 11.8 0.3 3.2 2 1 0 2 2 2 0 Double zinc ribbon RRN7 PF11781.3 EGD98119.1 - 0.07 12.6 0.2 0.07 12.6 0.1 2.7 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ribbon_3 PF13248.1 EGD98119.1 - 0.36 10.0 10.8 1.2 8.4 1.7 3.0 2 2 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.7 EGD98119.1 - 0.96 9.2 6.8 2 8.2 0.4 2.6 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.6 EGD98119.1 - 6.8 6.4 13.6 1.4 8.6 0.2 3.2 3 0 0 3 3 3 0 Putative transposase DNA-binding domain COPI_assoc PF08507.5 EGD98120.1 - 5.6e-43 145.9 4.2 5.9e-43 145.8 2.9 1.0 1 0 0 1 1 1 1 COPI associated protein SPC12 PF06645.8 EGD98120.1 - 0.73 9.6 5.6 0.099 12.4 0.6 1.8 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3784 PF12650.2 EGD98120.1 - 5.4 7.0 9.3 0.17 11.8 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DAO PF01266.19 EGD98121.1 - 1e-24 87.1 0.2 7.9e-15 54.6 0.1 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGD98121.1 - 0.00086 19.6 0.1 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD98121.1 - 0.0016 18.4 0.1 0.0036 17.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EGD98121.1 - 0.058 13.6 0.0 0.1 12.8 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF1188 PF06690.6 EGD98121.1 - 0.069 12.2 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Saccharop_dh PF03435.13 EGD98121.1 - 0.069 12.1 0.2 0.13 11.1 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Thi4 PF01946.12 EGD98121.1 - 0.098 11.7 0.1 0.098 11.7 0.1 1.6 2 0 0 2 2 2 0 Thi4 family GMC_oxred_N PF00732.14 EGD98121.1 - 0.1 11.7 0.2 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 GMC oxidoreductase ApbA PF02558.11 EGD98121.1 - 0.11 11.9 0.2 0.29 10.5 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glyco_transf_54 PF04666.8 EGD98122.1 - 0.0088 14.8 0.0 0.22 10.2 0.0 2.1 2 0 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region FTCD PF02971.9 EGD98122.1 - 0.16 11.6 0.0 0.63 9.6 0.0 1.9 2 0 0 2 2 2 0 Formiminotransferase domain F-box-like PF12937.2 EGD98125.1 - 0.00078 19.1 0.8 0.0016 18.0 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD98125.1 - 0.0016 18.0 1.4 0.0032 17.0 1.0 1.5 1 0 0 1 1 1 1 F-box domain HNH_2 PF13391.1 EGD98127.1 - 0.00081 19.1 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease peroxidase PF00141.18 EGD98128.1 - 5.1e-51 173.3 0.0 7.9e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4366 PF14283.1 EGD98128.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) ERG2_Sigma1R PF04622.7 EGD98129.1 - 1.2e-65 220.7 0.2 1.3e-65 220.6 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein zf-CSL PF05207.8 EGD98130.1 - 1.3e-16 59.8 0.4 2e-16 59.1 0.3 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EGD98130.1 - 1.4e-15 56.7 0.0 2.5e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain PITH PF06201.8 EGD98131.1 - 1.9e-35 121.8 0.0 4.7e-35 120.6 0.0 1.7 1 1 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EGD98131.1 - 1e-24 86.2 0.0 2e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGD98131.1 - 9.7e-08 32.0 0.1 1.1e-06 28.6 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EGD98131.1 - 5e-05 23.2 0.3 0.00011 22.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGD98131.1 - 7.5e-05 22.8 0.1 0.00059 20.0 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EGD98131.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EGD98131.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.5 EGD98131.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Redoxin Phosducin PF02114.11 EGD98131.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Phosducin zf-C2H2 PF00096.21 EGD98133.1 - 4.7e-12 45.4 13.3 1.2e-06 28.4 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD98133.1 - 3.1e-09 36.5 11.0 0.00031 20.8 3.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD98133.1 - 1.9e-06 27.8 4.7 0.0028 17.7 0.6 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EGD98133.1 - 3.5e-06 27.0 14.4 7.9e-06 25.9 2.6 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 EGD98133.1 - 0.0019 18.3 11.0 0.0039 17.3 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGD98133.1 - 0.0034 17.2 0.6 0.0034 17.2 0.4 2.7 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGD98133.1 - 0.34 11.0 4.2 7.9 6.6 0.2 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.6 EGD98133.1 - 0.97 9.1 3.2 2.4 7.9 0.2 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-trcl PF13451.1 EGD98133.1 - 1 9.0 4.3 0.6 9.7 0.5 2.2 2 0 0 2 2 2 0 Probable zinc-binding domain ATP_bind_4 PF01902.12 EGD98134.1 - 1e-18 67.5 0.0 1.7e-05 24.2 0.0 4.2 3 1 0 3 3 3 3 ATP-binding region Ribonuc_L-PSP PF01042.16 EGD98134.1 - 2.7e-11 43.2 0.1 4.7e-06 26.3 0.0 3.9 3 1 0 3 3 3 2 Endoribonuclease L-PSP Pkinase PF00069.20 EGD98135.1 - 2.6e-09 36.6 0.0 4.7e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGD98135.1 - 1.6e-08 34.5 1.1 2.6e-05 24.0 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EGD98135.1 - 8.2e-08 31.6 0.0 3.8e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EGD98135.1 - 0.00088 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGD98135.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 EGD98135.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 EGD98135.1 - 0.16 11.5 0.0 0.69 9.4 0.0 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase CTP_transf_1 PF01148.15 EGD98137.1 - 5e-05 23.0 13.0 5e-05 23.0 9.0 3.6 2 2 0 2 2 2 1 Cytidylyltransferase family DUF3543 PF12063.3 EGD98138.1 - 3.3e-94 314.5 0.1 6e-94 313.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EGD98138.1 - 7.6e-62 208.7 0.0 3e-61 206.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98138.1 - 5.7e-42 143.5 0.0 2.7e-41 141.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PAZ PF02170.17 EGD98138.1 - 0.017 14.3 0.1 0.045 13.0 0.1 1.7 1 0 0 1 1 1 0 PAZ domain Kinase-like PF14531.1 EGD98138.1 - 0.028 13.3 0.0 2.4 7.0 0.0 2.5 3 0 0 3 3 3 0 Kinase-like APH PF01636.18 EGD98138.1 - 0.058 13.1 1.2 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family AA_permease_2 PF13520.1 EGD98139.1 - 7.7e-95 317.9 34.9 1e-94 317.5 24.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD98139.1 - 1.5e-23 82.9 31.8 3.5e-23 81.7 22.1 1.5 1 1 0 1 1 1 1 Amino acid permease Peptidase_M1 PF01433.15 EGD98140.1 - 2e-141 471.6 1.7 2.8e-141 471.1 1.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EGD98140.1 - 6.1e-93 311.6 0.8 2.4e-92 309.6 0.1 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGD98140.1 - 1.4e-20 73.6 0.5 2.5e-20 72.8 0.3 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DEAD PF00270.24 EGD98141.1 - 2.7e-40 137.6 0.0 2.1e-39 134.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD98141.1 - 7.2e-26 89.8 0.2 1.7e-25 88.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2984 PF11203.3 EGD98141.1 - 0.046 13.8 1.8 0.12 12.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) PRAI PF00697.17 EGD98141.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF3334 PF11813.3 EGD98141.1 - 0.22 11.0 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) DUF2986 PF11661.3 EGD98141.1 - 0.32 11.3 9.0 0.049 13.9 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) p450 PF00067.17 EGD98143.1 - 2.4e-21 75.8 0.1 7.3e-21 74.2 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 FAD_binding_4 PF01565.18 EGD98144.1 - 5.3e-20 71.3 5.9 4.3e-19 68.3 4.1 2.2 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD98144.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Suf PF05843.9 EGD98145.1 - 0.0033 17.1 2.7 0.01 15.5 0.1 2.7 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) FAT PF02259.18 EGD98145.1 - 0.0046 15.9 1.4 0.017 14.1 0.0 2.5 3 0 0 3 3 3 1 FAT domain TPR_19 PF14559.1 EGD98145.1 - 0.013 15.8 0.2 42 4.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGD98145.1 - 0.019 15.5 13.6 0.085 13.5 0.1 6.2 6 2 2 8 8 8 0 Tetratricopeptide repeat Fe_hyd_SSU PF02256.12 EGD98145.1 - 0.061 13.3 1.1 2 8.4 0.0 2.9 2 0 0 2 2 2 0 Iron hydrogenase small subunit TPR_16 PF13432.1 EGD98145.1 - 1.3 9.8 7.1 20 5.9 0.0 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat Aminotran_5 PF00266.14 EGD98147.1 - 5.1e-26 91.2 0.0 7.7e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EGD98147.1 - 3.4e-25 88.0 0.0 6.2e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EGD98147.1 - 1.6e-17 63.2 0.1 3.9e-17 61.9 0.0 1.7 2 0 0 2 2 2 1 MOSC domain MARVEL PF01284.18 EGD98148.1 - 0.00087 19.1 0.3 0.0016 18.2 0.2 1.4 1 0 0 1 1 1 1 Membrane-associating domain Kei1 PF08552.6 EGD98148.1 - 0.0034 17.0 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 SAGA-Tad1 PF12767.2 EGD98149.1 - 0.14 11.7 2.8 0.18 11.4 1.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Pap_E4 PF02711.9 EGD98149.1 - 2 9.2 6.1 2.9 8.7 4.2 1.2 1 0 0 1 1 1 0 E4 protein PAP2 PF01569.16 EGD98150.1 - 2.2e-19 69.4 0.9 3.5e-19 68.7 0.2 1.7 2 0 0 2 2 2 1 PAP2 superfamily Git3 PF11710.3 EGD98150.1 - 0.4 10.2 2.9 2.6 7.5 0.2 2.7 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 SLEI_Leptospira PF07620.6 EGD98152.1 - 0.17 11.7 0.8 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 SLEI But2 PF09792.4 EGD98153.1 - 6.8e-52 175.0 0.1 8.5e-52 174.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Lactamase_B PF00753.22 EGD98154.1 - 0.0019 17.9 0.1 0.017 14.7 0.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BTV_NS2 PF04514.7 EGD98155.1 - 0.37 9.6 4.0 0.49 9.2 2.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 NGP1NT PF08153.7 EGD98156.1 - 6.5e-49 165.1 0.1 9.9e-49 164.6 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EGD98156.1 - 1.1e-17 64.1 0.1 1.9e-14 53.6 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EGD98156.1 - 2.6e-05 23.5 0.0 0.0001 21.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGD98156.1 - 0.0033 17.2 0.6 0.29 10.9 0.0 3.5 3 1 1 4 4 4 1 Dynamin family DUF258 PF03193.11 EGD98156.1 - 0.005 16.0 0.0 0.0099 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 EGD98156.1 - 0.0079 15.4 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family SusD-like_3 PF14322.1 EGD98156.1 - 0.036 14.1 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Grp1_Fun34_YaaH PF01184.14 EGD98157.1 - 1.1e-48 165.3 6.8 1.5e-48 164.8 4.7 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family YrhC PF14143.1 EGD98157.1 - 3.1 7.8 7.9 1.9 8.4 3.7 2.0 1 1 1 2 2 2 0 YrhC-like protein DUF2207 PF09972.4 EGD98157.1 - 4 5.9 5.6 5 5.5 3.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) p450 PF00067.17 EGD98158.1 - 9.9e-77 258.4 0.0 1.2e-76 258.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TFIIE_alpha PF02002.12 EGD98158.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 TFIIE alpha subunit Pkinase PF00069.20 EGD98159.1 - 6.4e-41 140.2 0.0 2.6e-40 138.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98159.1 - 1.1e-28 99.9 0.0 1.6e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD98159.1 - 0.038 12.9 0.0 0.089 11.7 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 EGD98159.1 - 0.32 9.7 0.0 0.51 9.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Prefoldin_3 PF13758.1 EGD98160.1 - 1.1e-32 111.7 0.1 3.5e-32 110.0 0.0 1.9 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 EGD98160.1 - 1.3e-23 83.6 10.3 5.9e-21 75.2 0.2 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3835) Lzipper-MIP1 PF14389.1 EGD98160.1 - 0.007 16.4 0.3 0.8 9.8 0.0 2.9 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Prefoldin_2 PF01920.15 EGD98160.1 - 0.023 14.4 1.5 3.9 7.2 0.0 3.3 3 0 0 3 3 3 0 Prefoldin subunit MerR-DNA-bind PF09278.6 EGD98160.1 - 0.18 12.2 1.0 32 5.0 0.0 3.1 3 0 0 3 3 3 0 MerR, DNA binding Zip PF02535.17 EGD98161.1 - 2e-35 122.3 19.1 2e-35 122.3 13.2 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter MAT1 PF06391.8 EGD98162.1 - 1.7e-36 125.7 17.7 2.2e-36 125.3 12.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EGD98162.1 - 0.00013 21.5 3.7 0.00034 20.1 2.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD98162.1 - 0.00034 20.2 5.2 0.00069 19.2 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD98162.1 - 0.0039 17.1 5.8 0.009 16.0 4.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD98162.1 - 0.0087 15.7 7.1 0.057 13.1 5.3 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGD98162.1 - 0.016 15.0 5.9 0.032 14.0 4.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 EGD98162.1 - 0.018 14.6 5.3 0.084 12.4 1.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Rab5-bind PF09311.6 EGD98163.1 - 0.13 12.1 2.0 0.29 11.0 1.4 1.5 1 0 0 1 1 1 0 Rabaptin-like protein adh_short PF00106.20 EGD98164.1 - 1.6e-12 47.6 0.0 2.6e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD98164.1 - 0.001 18.7 0.1 0.0027 17.3 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EGD98164.1 - 0.0021 18.1 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EGD98164.1 - 0.034 13.9 0.0 0.048 13.4 0.0 1.4 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EGD98164.1 - 0.055 12.5 0.0 0.35 9.9 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) F-box-like PF12937.2 EGD98166.1 - 0.0002 21.0 0.1 0.00055 19.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like NHR2 PF08788.6 EGD98166.1 - 0.088 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 NHR2 domain like CoaE PF01121.15 EGD98167.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase PEX11 PF05648.9 EGD98168.1 - 4.2e-33 114.4 0.0 5.4e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Flavodoxin_1 PF00258.20 EGD98169.1 - 2.5e-11 43.7 0.0 3.8e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EGD98169.1 - 4.5e-09 35.9 0.0 5.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EGD98169.1 - 1.4e-07 31.2 0.0 1.8e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EGD98169.1 - 0.00013 22.0 0.0 0.00082 19.3 0.0 2.0 1 1 0 1 1 1 1 Flavodoxin domain Flavodoxin_4 PF12682.2 EGD98169.1 - 0.15 11.4 0.6 1.3 8.3 0.4 2.1 1 1 0 1 1 1 0 Flavodoxin NPL4 PF05021.10 EGD98170.1 - 3e-128 427.2 0.0 3.8e-128 426.9 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EGD98170.1 - 5.8e-70 233.6 0.2 8.9e-70 233.0 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region Kinesin PF00225.18 EGD98171.1 - 6.6e-14 51.3 0.0 1.4e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain TSC22 PF01166.13 EGD98171.1 - 0.051 13.5 0.7 0.15 12.0 0.5 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family MBD PF01429.14 EGD98172.1 - 0.14 11.7 0.2 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Methyl-CpG binding domain Tim17 PF02466.14 EGD98173.1 - 0.00036 20.5 4.2 0.00075 19.5 2.9 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Asp_Glu_race_2 PF14669.1 EGD98173.1 - 0.052 12.8 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative aspartate racemase gpUL132 PF11359.3 EGD98174.1 - 9.7 5.4 6.6 21 4.3 0.1 2.2 2 0 0 2 2 2 0 Glycoprotein UL132 SPC25 PF06703.6 EGD98175.1 - 0.28 10.7 2.8 2 8.0 0.3 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) cNMP_binding PF00027.24 EGD98176.1 - 9.8e-36 121.4 0.0 8.4e-20 70.3 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EGD98176.1 - 6.1e-13 47.3 12.3 0.071 13.2 0.0 9.6 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.28 EGD98176.1 - 5e-07 28.8 9.0 8.1 6.9 0.0 8.8 9 1 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.1 EGD98176.1 - 2.5e-06 27.1 0.3 0.017 14.8 0.5 5.1 4 1 1 5 5 5 1 Leucine rich repeat F-box-like PF12937.2 EGD98176.1 - 0.00025 20.6 1.8 0.00046 19.8 0.4 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGD98176.1 - 0.0031 17.1 0.7 0.0031 17.1 0.5 3.3 3 0 0 3 3 3 1 F-box domain LRR_7 PF13504.1 EGD98176.1 - 0.0082 16.1 14.2 45 4.9 0.0 8.2 8 0 0 8 8 8 0 Leucine rich repeat LRR_4 PF12799.2 EGD98176.1 - 0.051 13.2 6.6 0.67 9.6 0.0 5.0 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) Ste50p-SAM PF09235.5 EGD98176.1 - 0.096 12.7 3.4 8.1 6.5 0.4 3.9 3 2 0 3 3 3 0 Ste50p, sterile alpha motif Zn_clus PF00172.13 EGD98177.1 - 9.5e-08 31.8 7.8 1.5e-07 31.1 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RasGAP_C PF03836.10 EGD98177.1 - 0.032 13.9 0.0 0.032 13.9 0.0 2.1 2 0 0 2 2 2 0 RasGAP C-terminus DUF904 PF06005.7 EGD98177.1 - 0.032 14.5 0.0 0.032 14.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EGD98177.1 - 0.055 13.8 0.0 0.055 13.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF972) HALZ PF02183.13 EGD98177.1 - 0.092 12.4 1.3 0.18 11.5 0.2 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Shugoshin_N PF07558.6 EGD98177.1 - 0.28 10.9 2.3 0.61 9.8 1.5 1.7 1 1 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Slx4 PF09494.5 EGD98178.1 - 2.5e-27 94.4 0.6 4.6e-27 93.5 0.4 1.5 1 0 0 1 1 1 1 Slx4 endonuclease CGI-121 PF08617.5 EGD98179.1 - 7.5e-59 198.0 0.4 8.7e-59 197.7 0.3 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bax1-I PF01027.15 EGD98180.1 - 8.1e-30 103.9 11.2 8.1e-30 103.9 7.8 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 DUF2537 PF10801.3 EGD98180.1 - 0.17 12.0 6.1 3.2 7.9 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) Cutinase PF01083.17 EGD98182.1 - 1.6e-38 132.2 0.0 2e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.11 EGD98182.1 - 0.00057 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PE-PPE PF08237.6 EGD98182.1 - 0.082 12.3 0.1 0.3 10.4 0.1 1.9 1 1 0 1 1 1 0 PE-PPE domain RRM_1 PF00076.17 EGD98183.1 - 2e-15 56.1 0.0 3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD98183.1 - 6.1e-12 45.3 0.0 8.9e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD98183.1 - 1.5e-10 40.7 0.0 2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.9 EGD98184.1 - 1.1e-22 80.9 0.8 4.5e-15 55.8 0.0 2.7 3 1 0 3 3 3 2 Glycosyl hydrolase family 76 DUF2236 PF09995.4 EGD98185.1 - 1.8e-06 27.4 0.0 3.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) PigN PF04987.9 EGD98185.1 - 0.034 12.8 0.3 0.059 12.0 0.2 1.4 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF2205 PF10224.4 EGD98189.1 - 5.3e-25 86.7 0.2 9.5e-25 85.9 0.2 1.4 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Macoilin PF09726.4 EGD98189.1 - 0.0014 17.0 4.7 0.0017 16.7 3.3 1.0 1 0 0 1 1 1 1 Transmembrane protein DUF4201 PF13870.1 EGD98189.1 - 0.0079 15.6 0.4 0.011 15.1 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) CASP_C PF08172.7 EGD98189.1 - 0.019 14.0 0.9 0.019 14.0 0.7 2.1 2 0 0 2 2 2 0 CASP C terminal DUF972 PF06156.8 EGD98189.1 - 0.022 15.1 0.6 0.038 14.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 EGD98189.1 - 0.032 14.6 0.3 0.06 13.7 0.2 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Prefoldin PF02996.12 EGD98189.1 - 0.034 13.8 0.7 0.055 13.1 0.5 1.4 1 0 0 1 1 1 0 Prefoldin subunit DivIC PF04977.10 EGD98189.1 - 0.037 13.5 0.4 0.059 12.8 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator TFIIA PF03153.8 EGD98189.1 - 0.074 12.9 3.2 0.095 12.5 2.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF812 PF05667.6 EGD98189.1 - 0.08 11.4 2.2 0.087 11.3 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4208 PF13907.1 EGD98189.1 - 0.093 12.9 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) HALZ PF02183.13 EGD98189.1 - 0.26 11.0 1.6 2.4 7.9 0.0 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper Stm1_N PF09598.5 EGD98190.1 - 5.2 7.8 7.9 0.66 10.7 1.0 2.1 2 0 0 2 2 2 0 Stm1 APO_RNA-bind PF05634.6 EGD98191.1 - 0.022 13.9 1.7 0.027 13.6 1.1 1.3 1 1 0 1 1 1 0 APO RNA-binding Cache_2 PF08269.6 EGD98191.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 1 0 1 1 1 0 Cache domain 14-3-3 PF00244.15 EGD98193.1 - 1.8e-114 380.6 7.2 2.2e-114 380.4 5.0 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF3461 PF11944.3 EGD98193.1 - 0.096 12.5 2.7 0.5 10.2 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) IATP PF04568.7 EGD98194.1 - 5.6e-17 61.6 0.8 6.5e-17 61.3 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP BAG PF02179.11 EGD98194.1 - 0.048 13.7 0.5 0.061 13.4 0.4 1.2 1 0 0 1 1 1 0 BAG domain Vps5 PF09325.5 EGD98194.1 - 0.16 11.2 2.8 0.22 10.7 2.0 1.2 1 0 0 1 1 1 0 Vps5 C terminal like Nsp1_C PF05064.8 EGD98195.1 - 6.7e-43 145.0 3.7 6.7e-43 145.0 2.6 1.6 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EGD98195.1 - 0.00036 20.7 74.8 0.0034 17.5 21.2 4.6 1 1 3 4 4 3 2 Nucleoporin FG repeat region ParB PF08775.5 EGD98195.1 - 0.054 13.8 0.2 0.054 13.8 0.1 2.2 2 1 0 2 2 2 0 ParB family DUF4407 PF14362.1 EGD98195.1 - 0.12 11.2 6.6 0.2 10.5 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LOH1CR12 PF10158.4 EGD98195.1 - 0.15 11.8 0.7 0.91 9.3 0.0 2.2 2 0 0 2 2 2 0 Tumour suppressor protein ArsC PF03960.10 EGD98195.1 - 0.26 11.3 5.5 14 5.8 0.1 3.1 1 1 2 3 3 3 0 ArsC family Spc7 PF08317.6 EGD98195.1 - 0.55 8.8 12.7 0.33 9.5 0.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.2 EGD98195.1 - 0.58 9.9 11.2 0.059 13.2 3.4 2.0 1 1 1 2 2 2 0 Tropomyosin like DUF4200 PF13863.1 EGD98195.1 - 0.62 10.0 12.7 0.055 13.4 4.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.7 EGD98195.1 - 0.72 9.6 7.0 1.2 8.9 3.8 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 EGD98195.1 - 0.99 7.7 9.8 2 6.8 6.0 1.7 1 1 0 1 1 1 0 AAA domain MscS_porin PF12795.2 EGD98195.1 - 2.9 7.1 17.0 0.29 10.4 4.4 2.2 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain APG6 PF04111.7 EGD98195.1 - 3 6.8 10.8 6 5.8 7.5 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Syntaxin PF00804.20 EGD98195.1 - 3.1 8.0 6.7 71 3.6 4.6 2.3 1 1 0 1 1 1 0 Syntaxin MCPsignal PF00015.16 EGD98195.1 - 3.9 6.9 10.1 1.7 8.1 1.3 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CENP-Q PF13094.1 EGD98195.1 - 4.7 7.2 10.7 9.7 6.1 6.8 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FlaC_arch PF05377.6 EGD98195.1 - 5 7.1 6.9 6.1 6.8 0.2 2.5 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) V-SNARE PF05008.10 EGD98195.1 - 7.5 6.7 9.1 0.97 9.6 0.5 3.0 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Laminin_II PF06009.7 EGD98195.1 - 8.1 6.2 10.8 8.8 6.0 2.1 2.5 1 1 2 3 3 3 0 Laminin Domain II zf-MIZ PF02891.15 EGD98197.1 - 8.2e-11 41.2 0.1 2e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SH3_1 PF00018.23 EGD98198.1 - 8e-10 37.9 0.0 1.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD98198.1 - 3.8e-09 35.9 0.1 8.3e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 EGD98198.1 - 2.7e-08 33.5 0.1 5.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 EGD98198.1 - 0.00011 21.6 0.1 0.00021 20.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EGD98198.1 - 0.0032 17.6 0.1 0.006 16.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Gastrin PF00918.12 EGD98198.1 - 0.011 16.5 0.3 0.068 13.9 0.2 2.4 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Metallophos PF00149.23 EGD98199.1 - 4.7e-10 39.1 7.2 1.1e-09 38.0 5.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L14 PF00238.14 EGD98200.1 - 1.8e-30 105.1 0.0 2.1e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.14 EGD98201.1 - 1.2e-78 264.5 0.0 2e-78 263.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.16 EGD98202.1 - 5.5e-36 122.7 0.1 1.4e-35 121.4 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGD98202.1 - 5e-28 97.4 1.3 1e-27 96.4 0.9 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EGD98202.1 - 3.5e-09 36.1 0.0 1.1e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 EGD98202.1 - 0.028 14.1 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Swi5 PF07061.6 EGD98202.1 - 0.034 13.9 0.8 0.083 12.6 0.3 1.9 2 0 0 2 2 2 0 Swi5 NIF PF03031.13 EGD98204.1 - 2.4e-39 134.5 0.0 3.6e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EGD98204.1 - 0.072 13.2 0.4 0.28 11.3 0.0 2.1 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 EGD98205.1 - 3.2e-20 72.0 0.0 1.2e-19 70.2 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD98205.1 - 1.9e-06 27.6 6.3 3.8e-06 26.7 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EGD98207.1 - 0.00016 21.3 1.2 0.00041 20.0 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD98207.1 - 0.0053 16.3 1.4 0.011 15.4 1.0 1.5 1 0 0 1 1 1 1 F-box domain EspF PF04806.7 EGD98207.1 - 0.031 14.4 12.5 0.43 10.8 2.7 3.5 2 0 0 2 2 2 0 EspF protein repeat Fungal_trans PF04082.13 EGD98208.1 - 2.2e-12 46.4 0.7 4e-12 45.5 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD98208.1 - 7.4e-06 25.7 8.8 1.8e-05 24.5 6.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3133 PF11331.3 EGD98208.1 - 5.5 6.6 8.4 0.34 10.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) Pkinase PF00069.20 EGD98210.1 - 1.9e-69 233.7 0.0 2.9e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98210.1 - 4.8e-34 117.5 0.0 7.6e-33 113.6 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD98210.1 - 0.00078 18.4 0.3 0.72 8.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EGD98210.1 - 0.039 13.3 0.2 0.079 12.2 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 EGD98210.1 - 0.056 12.2 0.2 0.15 10.8 0.0 1.7 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.11 EGD98211.1 - 8.8e-28 97.0 34.8 1.4e-19 70.0 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD98211.1 - 6.5e-22 77.7 16.7 3.9e-21 75.1 11.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD98213.1 - 3.6e-13 48.9 18.7 3.6e-13 48.9 12.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD98213.1 - 0.00058 18.5 9.7 0.0011 17.6 6.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD98215.1 - 5.3e-06 25.3 12.3 5.9e-06 25.2 8.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD98215.1 - 0.039 12.5 10.4 0.044 12.3 7.2 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter DUF3789 PF12664.2 EGD98215.1 - 0.08 12.2 7.1 0.93 8.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) zf-ISL3 PF14690.1 EGD98216.1 - 0.078 13.0 2.4 0.86 9.6 0.3 2.6 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 M20_dimer PF07687.9 EGD98216.1 - 0.67 9.7 6.5 2 8.1 0.2 3.1 4 0 0 4 4 4 0 Peptidase dimerisation domain HAMP PF00672.20 EGD98217.1 - 8.9e-44 147.5 16.9 1.4e-09 37.9 0.4 6.9 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 EGD98217.1 - 9.9e-31 105.7 0.2 4.8e-30 103.5 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGD98217.1 - 2.3e-26 91.9 2.0 3.3e-24 85.0 0.2 3.1 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 EGD98217.1 - 5.1e-17 61.6 5.8 2.9e-16 59.2 0.0 4.5 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain NOD PF06816.8 EGD98217.1 - 0.03 13.4 0.1 0.87 8.7 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein Vps52 PF04129.7 EGD98217.1 - 0.032 12.7 3.8 3.2 6.1 0.1 3.8 4 0 0 4 4 4 0 Vps52 / Sac2 family Pox_A_type_inc PF04508.7 EGD98217.1 - 0.058 13.1 0.9 0.8 9.6 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat NAAA-beta PF15508.1 EGD98217.1 - 0.085 13.2 4.5 9.9 6.5 0.1 5.8 5 3 3 8 8 8 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Gp-FAR-1 PF05823.7 EGD98217.1 - 0.1 12.5 4.2 4.2 7.3 0.0 4.0 3 2 1 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) AAA_13 PF13166.1 EGD98217.1 - 0.3 9.4 25.8 0.69 8.3 0.9 4.1 1 1 2 4 4 4 0 AAA domain DUF948 PF06103.6 EGD98217.1 - 2.1 8.2 34.0 7.6 6.4 0.6 7.9 4 2 2 7 7 7 0 Bacterial protein of unknown function (DUF948) tRNA-synt_2d PF01409.15 EGD98218.1 - 1.6e-88 296.0 0.0 2.3e-88 295.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EGD98218.1 - 3.7e-06 25.9 0.6 0.0003 19.6 0.0 3.3 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EGD98218.1 - 0.0013 18.3 0.0 0.0076 15.8 0.0 2.1 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF2564 PF10819.3 EGD98218.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) Ribosomal_S21e PF01249.13 EGD98219.1 - 4.3e-29 100.2 0.2 8.8e-29 99.2 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.23 EGD98220.1 - 2.5e-13 49.8 0.0 1.4e-12 47.4 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.20 EGD98221.1 - 2e-134 447.9 3.4 2.4e-134 447.6 2.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EGD98221.1 - 1.4e-20 72.7 0.1 3.9e-10 39.3 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EGD98221.1 - 7.3e-08 31.6 0.9 1.5e-07 30.6 0.5 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EGD98221.1 - 3.3e-06 26.4 10.7 0.0019 17.4 5.8 2.6 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 EGD98221.1 - 8.7e-05 21.8 2.0 0.00023 20.5 1.4 1.6 1 1 0 1 1 1 1 Histidine biosynthesis protein PK PF00224.16 EGD98221.1 - 0.0014 17.3 0.0 0.0031 16.1 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Aldolase PF01081.14 EGD98221.1 - 0.0097 15.0 1.7 0.041 13.0 0.2 2.3 2 0 0 2 2 2 1 KDPG and KHG aldolase EAL PF00563.15 EGD98221.1 - 0.013 15.0 0.2 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 EAL domain ThiG PF05690.9 EGD98221.1 - 0.027 13.5 1.9 0.036 13.1 0.4 1.8 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DUF1273 PF06908.6 EGD98221.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) DHO_dh PF01180.16 EGD98221.1 - 0.77 8.6 4.7 0.59 9.0 0.2 2.4 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase RasGAP_C PF03836.10 EGD98222.1 - 1.1e-47 161.3 4.5 2.9e-47 159.9 3.1 1.8 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EGD98222.1 - 1.8e-41 142.0 0.0 4e-41 140.8 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 EGD98222.1 - 9.2e-13 48.1 0.0 6.2e-12 45.5 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 EGD98222.1 - 4.4e-10 38.2 40.9 0.23 11.2 0.0 14.8 16 1 1 17 17 17 4 IQ calmodulin-binding motif ENTH PF01417.15 EGD98223.1 - 4.7e-47 158.9 0.1 7.5e-47 158.2 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EGD98223.1 - 0.00049 18.9 0.0 0.00072 18.3 0.0 1.2 1 0 0 1 1 1 1 ANTH domain SH3_1 PF00018.23 EGD98224.1 - 5.1e-11 41.7 0.0 9.1e-11 40.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD98224.1 - 1.7e-10 40.3 0.0 2.9e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGD98224.1 - 1.7e-07 30.6 0.0 2.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.11 EGD98225.1 - 2.7e-26 92.1 50.1 3e-15 55.8 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGD98225.1 - 1.7e-10 39.8 13.6 1.7e-10 39.8 9.4 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein 7TM_GPCR_Srh PF10318.4 EGD98225.1 - 2e-05 23.5 1.3 2e-05 23.5 0.9 2.9 4 1 0 5 5 5 1 Serpentine type 7TM GPCR chemoreceptor Srh MFS_1_like PF12832.2 EGD98225.1 - 0.18 11.6 11.6 0.86 9.4 0.6 3.5 3 0 0 3 3 3 0 MFS_1 like family Pkinase PF00069.20 EGD98228.1 - 2.1e-65 220.4 0.0 3.4e-65 219.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98228.1 - 2.5e-35 121.7 0.0 4.6e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD98228.1 - 2.3e-08 33.3 0.0 6.4e-08 31.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGD98228.1 - 0.00014 21.7 0.0 0.0035 17.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGD98228.1 - 0.0082 15.0 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 EGD98228.1 - 0.089 12.1 0.3 0.18 11.1 0.2 1.4 1 0 0 1 1 1 0 RIO1 family RRM_1 PF00076.17 EGD98229.1 - 1.1e-17 63.4 0.1 1.6e-08 34.0 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD98229.1 - 3.8e-16 58.8 0.0 1.5e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD98229.1 - 1.3e-13 50.5 0.1 1.2e-09 37.8 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGD98229.1 - 0.0081 15.9 0.7 0.12 12.1 0.0 2.7 2 1 1 3 3 3 1 RNA binding motif Tubulin PF00091.20 EGD98230.1 - 1.9e-71 240.3 0.0 3.1e-71 239.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGD98230.1 - 1.8e-49 166.9 0.2 3e-49 166.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EGD98230.1 - 9.2e-06 25.6 0.0 2.4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EGD98230.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Aldedh PF00171.17 EGD98231.1 - 4.4e-106 354.9 0.0 5.6e-106 354.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2236 PF09995.4 EGD98232.1 - 1e-07 31.5 0.1 1.5e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) AGT PF11440.3 EGD98232.1 - 0.021 13.7 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Methyltransf_31 PF13847.1 EGD98233.1 - 2.6e-11 43.3 0.0 3.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD98233.1 - 9.6e-09 35.1 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD98233.1 - 9e-08 32.5 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD98233.1 - 1.9e-07 31.6 0.0 5.5e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD98233.1 - 2e-05 25.0 0.0 3.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD98233.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EGD98233.1 - 0.027 13.5 0.0 0.062 12.4 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CheR PF01739.13 EGD98233.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.1 EGD98233.1 - 0.03 14.6 0.0 0.085 13.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Isochorismatase PF00857.15 EGD98234.1 - 1.4e-33 116.2 0.1 4.4e-33 114.6 0.0 1.7 2 0 0 2 2 2 1 Isochorismatase family Iso_dh PF00180.15 EGD98234.1 - 5.5e-13 48.5 0.0 9.2e-08 31.4 0.0 2.4 2 1 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase TK PF00265.13 EGD98234.1 - 0.01 15.3 0.0 0.058 12.9 0.0 2.1 2 0 0 2 2 2 0 Thymidine kinase Methyltransf_25 PF13649.1 EGD98235.1 - 3.5e-11 43.3 0.1 8.4e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD98235.1 - 7.1e-07 29.0 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD98235.1 - 8.4e-06 25.4 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD98235.1 - 1.5e-05 25.3 0.0 2.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD98235.1 - 4e-05 24.0 0.0 5.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD98235.1 - 0.0021 18.6 0.0 0.0032 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD98235.1 - 0.053 12.6 0.0 0.069 12.2 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Abhydrolase_6 PF12697.2 EGD98236.1 - 1.7e-11 44.4 0.0 2.1e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD98236.1 - 6.5e-08 32.4 0.0 8.9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Aminotran_1_2 PF00155.16 EGD98236.1 - 0.085 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Rad60-SLD PF11976.3 EGD98238.1 - 8.1e-22 76.7 0.2 1e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGD98238.1 - 9.4e-10 37.7 0.1 1.2e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 EGD98238.1 - 0.07 12.8 0.2 0.12 12.1 0.1 1.4 1 1 1 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) DUF1903 PF08991.5 EGD98239.1 - 7.5e-23 80.4 8.2 8.5e-23 80.2 5.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EGD98239.1 - 0.011 15.6 6.4 0.018 14.9 4.4 1.4 1 0 0 1 1 1 0 CHCH domain Nup84_Nup100 PF04121.8 EGD98240.1 - 7.4e-60 202.4 2.1 2.6e-58 197.3 1.5 2.8 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 PEP-utilizers_C PF02896.13 EGD98240.1 - 0.15 10.9 0.0 0.32 9.8 0.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Nop14 PF04147.7 EGD98240.1 - 1 7.2 19.3 1.9 6.3 13.3 1.4 1 0 0 1 1 1 0 Nop14-like family E1-E2_ATPase PF00122.15 EGD98242.1 - 1.4e-58 197.6 3.2 3.5e-58 196.3 2.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD98242.1 - 4.1e-45 153.5 4.7 4.1e-45 153.5 3.3 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD98242.1 - 1.4e-26 94.2 0.0 3.4e-26 93.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGD98242.1 - 1.4e-12 48.1 0.0 3.5e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD98242.1 - 5.6e-08 32.6 0.1 1.3e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGD98242.1 - 2.7e-06 26.7 0.1 2e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGD98242.1 - 1.1e-05 25.1 0.6 4.4e-05 23.1 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EGD98242.1 - 0.0027 17.6 0.3 0.2 11.6 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3325) OPA3 PF07047.7 EGD98243.1 - 0.019 14.7 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) TEX19 PF15553.1 EGD98243.1 - 1.5 8.6 4.5 0.29 10.9 0.4 1.7 2 0 0 2 2 2 0 Testis-expressed protein 19 RR_TM4-6 PF06459.7 EGD98243.1 - 4.4 7.1 10.7 5.4 6.8 7.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nucleo_P87 PF07267.6 EGD98243.1 - 6.9 5.2 8.6 8.7 4.8 5.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Agouti PF05039.7 EGD98243.1 - 7.5 6.9 7.9 5.5 7.3 0.9 2.3 2 0 0 2 2 2 0 Agouti protein Ligase_CoA PF00549.14 EGD98244.1 - 5.9e-34 116.8 2.3 6.4e-18 64.8 0.1 2.2 2 0 0 2 2 2 2 CoA-ligase Succ_CoA_lig PF13607.1 EGD98244.1 - 8.5e-11 41.6 0.3 1.1e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain 4HBT PF03061.17 EGD98245.1 - 7.2e-11 42.0 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily V-ATPase_C PF03223.10 EGD98246.1 - 1.3e-118 396.1 0.0 1.4e-118 396.0 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 EGD98246.1 - 0.081 13.2 0.7 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain APS_kinase PF01583.15 EGD98247.1 - 7.5e-52 175.1 0.0 1.2e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EGD98247.1 - 3.8e-06 26.8 1.1 1.9e-05 24.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGD98247.1 - 4e-06 27.1 0.9 2.1e-05 24.8 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGD98247.1 - 0.00017 22.4 0.2 0.00017 22.4 0.1 2.4 1 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGD98247.1 - 0.0014 18.1 0.9 0.0033 16.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EGD98247.1 - 0.015 14.7 0.7 0.28 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGD98247.1 - 0.038 14.3 2.0 0.058 13.6 0.0 2.3 3 1 0 3 3 3 0 ABC transporter AAA_14 PF13173.1 EGD98247.1 - 0.038 13.8 0.1 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EGD98247.1 - 0.089 11.9 0.2 0.29 10.2 0.0 1.9 2 1 0 2 2 2 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 EGD98247.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 EGD98247.1 - 0.3 11.0 7.3 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.12 EGD98247.1 - 1 8.7 4.2 0.32 10.3 0.1 2.4 3 1 0 3 3 3 0 Thymidylate kinase GCV_T PF01571.16 EGD98248.1 - 7.4e-55 185.5 0.0 1e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EGD98248.1 - 2.7e-19 68.9 0.5 8.3e-19 67.4 0.2 1.9 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain Aa_trans PF01490.13 EGD98249.1 - 1.5e-26 92.8 34.1 2.6e-26 92.0 23.7 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Shisa PF13908.1 EGD98249.1 - 5.1 7.2 5.5 30 4.7 0.4 3.1 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Ank_2 PF12796.2 EGD98250.1 - 2e-42 143.4 0.1 7.2e-18 64.7 0.0 3.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD98250.1 - 4.2e-29 100.3 1.4 3.4e-10 40.1 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EGD98250.1 - 3e-26 89.8 1.3 0.00031 20.3 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EGD98250.1 - 1.9e-21 75.5 0.2 9.7e-08 32.0 0.0 5.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD98250.1 - 3.4e-21 73.1 4.1 0.0013 18.7 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat DUF3902 PF13042.1 EGD98250.1 - 0.016 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) NPR1_like_C PF12313.3 EGD98251.1 - 0.065 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal GreA_GreB_N PF03449.10 EGD98253.1 - 0.0065 16.4 3.4 3.1 7.9 0.0 4.3 4 0 0 4 4 4 1 Transcription elongation factor, N-terminal Fe-ADH_2 PF13685.1 EGD98253.1 - 0.12 11.6 1.0 0.19 10.9 0.1 1.7 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase Reo_sigmaC PF04582.7 EGD98253.1 - 0.61 9.2 7.2 0.46 9.6 0.5 2.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein TnpV PF14198.1 EGD98254.1 - 0.3 11.0 3.4 0.29 11.0 0.8 2.2 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Guanylate_kin PF00625.16 EGD98256.1 - 1.1e-45 155.3 0.0 1.2e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase Vac_ImportDeg PF09783.4 EGD98257.1 - 1.3e-68 229.9 1.4 1.8e-68 229.5 1.0 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Ebola_NP PF05505.7 EGD98257.1 - 7.1 4.5 8.4 8.9 4.2 5.8 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Mago_nashi PF02792.9 EGD98258.1 - 5.9e-74 246.5 0.4 7.6e-74 246.1 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.15 EGD98259.1 - 9.8e-94 314.5 11.9 9.8e-94 314.5 8.2 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EGD98259.1 - 1.6e-61 205.7 0.1 8.7e-61 203.3 0.0 2.3 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EGD98259.1 - 4.2e-61 204.7 1.1 9.8e-61 203.5 0.7 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EGD98259.1 - 3.4e-12 46.4 8.9 7.6e-08 32.5 0.0 4.4 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.2 EGD98259.1 - 3.8e-06 26.8 11.8 0.0054 16.6 0.0 4.1 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EGD98259.1 - 1.4e-05 25.4 4.8 0.0008 19.8 0.1 4.8 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.17 EGD98259.1 - 0.00024 20.9 1.1 0.41 10.8 0.0 4.7 5 0 0 5 5 4 1 HEAT repeat DUF1542 PF07564.6 EGD98259.1 - 0.0057 16.6 2.4 0.021 14.8 1.7 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1542) RE_Alw26IDE PF09665.5 EGD98259.1 - 0.0072 15.1 2.4 1.4 7.5 0.2 2.9 2 1 0 2 2 2 2 Type II restriction endonuclease (RE_Alw26IDE) AP4E_app_platf PF14807.1 EGD98259.1 - 0.041 14.1 0.1 0.18 12.0 0.1 2.2 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Arm PF00514.18 EGD98259.1 - 0.1 12.4 0.7 9.9 6.1 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF1180 PF06679.7 EGD98260.1 - 0.099 12.5 0.4 5.2 6.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) NfeD PF01957.13 EGD98260.1 - 0.28 11.3 0.1 0.28 11.3 0.1 2.6 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding DAGK_cat PF00781.19 EGD98262.1 - 3.1e-24 84.8 0.1 5.3e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pkinase PF00069.20 EGD98263.1 - 7.7e-78 261.2 0.0 1.4e-77 260.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98263.1 - 2.5e-41 141.4 0.0 6.6e-41 140.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EGD98263.1 - 3.6e-17 61.5 0.2 6.1e-17 60.8 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EGD98263.1 - 1.6e-06 27.3 0.0 3.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD98263.1 - 2.1e-05 23.6 0.0 0.00012 21.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGD98263.1 - 0.002 17.8 0.1 0.038 13.7 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 EGD98263.1 - 0.0052 16.0 0.1 0.0087 15.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 EGD98263.1 - 0.0088 15.4 0.4 0.024 13.9 0.3 1.7 1 1 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EGD98263.1 - 0.018 14.4 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1604 PF07713.8 EGD98264.1 - 7.6e-42 141.0 10.2 3.6e-40 135.6 1.9 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EGD98264.1 - 8.1e-08 31.9 1.5 1.7e-07 30.9 0.4 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EGD98264.1 - 0.026 14.3 0.4 0.026 14.3 0.3 3.5 2 1 1 3 3 3 0 DExH-box splicing factor binding site SLT_2 PF13406.1 EGD98264.1 - 0.033 13.0 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase SLT domain ubiquitin PF00240.18 EGD98265.1 - 3.2e-05 23.2 0.0 5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGD98265.1 - 0.003 17.1 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Nop52 PF05997.7 EGD98266.1 - 1.2e-48 165.4 0.3 2.8e-39 134.8 0.5 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 TAN PF11640.3 EGD98266.1 - 0.081 12.6 0.1 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair NOT2_3_5 PF04153.13 EGD98266.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family SET PF00856.23 EGD98267.1 - 1.3e-21 77.6 0.1 4.7e-21 75.7 0.1 2.0 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EGD98267.1 - 1.7e-12 47.4 4.0 1.7e-12 47.4 2.8 1.9 2 0 0 2 2 2 1 Pre-SET motif Ion_trans PF00520.26 EGD98270.1 - 1e-105 351.3 83.4 4.3e-32 110.9 5.0 5.1 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.27 EGD98270.1 - 0.0033 16.6 0.0 0.013 14.7 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EGD98270.1 - 0.045 13.6 0.0 0.37 10.8 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 EGD98270.1 - 0.089 12.9 0.0 0.35 11.0 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair Proteasom_Rpn13 PF04683.8 EGD98271.1 - 4.4e-28 97.2 0.0 6.6e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ribosomal_L6e PF01159.14 EGD98272.1 - 2.3e-34 117.9 0.0 3.7e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e FA_hydroxylase PF04116.8 EGD98273.1 - 4.9e-11 43.0 15.1 4.9e-11 43.0 10.5 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.20 EGD98274.1 - 4.9e-23 81.8 0.0 6.5e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD98274.1 - 4e-11 42.8 0.0 1.1e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD98274.1 - 3.4e-05 23.7 0.0 5.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGD98274.1 - 9.9e-05 22.4 1.0 0.00031 20.7 0.2 2.2 2 2 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 EGD98274.1 - 0.00066 19.7 0.1 0.0024 17.9 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EGD98274.1 - 0.0013 18.2 0.0 0.0024 17.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGD98274.1 - 0.0046 16.7 1.4 0.0058 16.3 0.2 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EGD98274.1 - 0.0059 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_transf_4 PF13439.1 EGD98274.1 - 0.011 15.4 0.2 0.066 12.9 0.2 2.0 1 1 0 1 1 1 0 Glycosyltransferase Family 4 NAD_binding_7 PF13241.1 EGD98274.1 - 0.028 14.6 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Saccharop_dh PF03435.13 EGD98274.1 - 0.034 13.1 0.1 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EGD98274.1 - 0.11 12.1 0.1 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sas10 PF09368.5 EGD98275.1 - 8.3e-29 99.5 6.8 8.3e-29 99.5 4.7 3.1 3 1 1 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EGD98275.1 - 4e-14 52.5 0.1 1.7e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family MutS_V PF00488.16 EGD98276.1 - 3.6e-56 190.2 0.0 8.7e-56 188.9 0.0 1.6 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGD98276.1 - 2.3e-25 89.5 0.0 4.6e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EGD98276.1 - 0.0057 16.7 0.1 0.023 14.8 0.0 2.1 2 0 0 2 2 2 1 MutS family domain IV AAA PF00004.24 EGD98276.1 - 0.082 13.1 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EGD98277.1 - 4.9e-46 156.7 0.0 2.4e-44 151.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EGD98277.1 - 4e-26 90.7 0.1 1.5e-25 88.9 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EGD98277.1 - 7.6e-18 64.9 0.0 4.7e-09 36.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGD98277.1 - 1.2e-12 47.7 0.1 1.3e-07 31.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGD98277.1 - 1.2e-10 41.7 12.6 0.00011 22.2 0.0 5.7 4 2 1 6 6 6 3 AAA ATPase domain AAA_22 PF13401.1 EGD98277.1 - 2.2e-09 37.5 0.9 0.00063 19.8 0.0 3.4 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EGD98277.1 - 7.2e-08 32.0 0.3 0.0002 20.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 EGD98277.1 - 1.1e-05 25.3 0.1 0.24 11.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EGD98277.1 - 2.6e-05 23.7 0.0 0.1 12.0 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein NACHT PF05729.7 EGD98277.1 - 2.7e-05 23.9 0.3 0.17 11.5 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.1 EGD98277.1 - 7.8e-05 22.9 2.7 0.082 13.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EGD98277.1 - 0.00011 21.8 0.0 0.0073 16.0 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 EGD98277.1 - 0.00014 21.5 0.1 0.11 12.1 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EGD98277.1 - 0.00017 21.3 7.2 0.12 12.0 0.1 4.6 3 2 0 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 EGD98277.1 - 0.00019 20.9 0.5 0.085 12.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGD98277.1 - 0.00023 21.1 2.3 0.05 13.5 0.0 3.6 3 1 0 4 4 3 1 AAA domain AAA_17 PF13207.1 EGD98277.1 - 0.00024 21.9 4.9 0.52 11.1 0.0 3.8 4 1 0 4 4 2 2 AAA domain SRP54 PF00448.17 EGD98277.1 - 0.00086 18.7 0.1 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 EGD98277.1 - 0.00088 17.9 0.1 0.14 10.7 0.0 2.5 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 EGD98277.1 - 0.0036 16.4 0.1 1.5 7.9 0.1 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EGD98277.1 - 0.0038 17.3 0.1 1.7 8.8 0.0 2.8 2 1 0 2 2 2 1 RNA helicase ResIII PF04851.10 EGD98277.1 - 0.0041 16.9 4.0 2.2 8.0 0.0 3.5 3 1 0 4 4 3 2 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EGD98277.1 - 0.0072 16.6 1.0 0.56 10.4 0.0 3.0 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.1 EGD98277.1 - 0.0091 15.8 0.1 6.1 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGD98277.1 - 0.0097 15.0 0.0 0.34 9.9 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin PduV-EutP PF10662.4 EGD98277.1 - 0.01 15.3 0.0 0.57 9.6 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EGD98277.1 - 0.014 14.9 2.1 0.23 11.0 0.0 3.6 5 0 0 5 5 4 0 AAA domain AAA_24 PF13479.1 EGD98277.1 - 0.018 14.5 0.0 0.86 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EGD98277.1 - 0.021 13.7 0.3 0.59 9.0 0.1 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF815) Miro PF08477.8 EGD98277.1 - 0.024 15.1 0.1 2.5 8.5 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EGD98277.1 - 0.027 13.6 0.1 3.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 UvrD-helicase PF00580.16 EGD98277.1 - 0.029 13.6 2.3 0.35 10.1 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ERM PF00769.14 EGD98277.1 - 0.054 13.0 10.8 0.098 12.1 7.5 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ATP_bind_1 PF03029.12 EGD98277.1 - 0.068 12.7 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EGD98277.1 - 0.07 12.5 1.4 0.5 9.7 0.0 2.9 3 1 0 3 3 3 0 AAA-like domain UPF0079 PF02367.12 EGD98277.1 - 0.088 12.4 0.1 21 4.7 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 HisKA_2 PF07568.7 EGD98277.1 - 0.28 11.0 1.5 0.89 9.4 0.6 2.2 2 0 0 2 2 2 0 Histidine kinase OEP PF02321.13 EGD98277.1 - 10 5.6 12.4 24 4.4 8.6 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein EF1_GNE PF00736.14 EGD98278.1 - 6.6e-31 105.8 1.3 1.2e-30 104.9 0.9 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EGD98278.1 - 1.9e-07 31.0 1.8 1.9e-07 31.0 1.3 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EGD98278.1 - 0.023 15.1 0.0 0.061 13.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGD98278.1 - 0.043 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4604 PF15377.1 EGD98278.1 - 0.13 12.4 2.4 0.2 11.8 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) MMgT PF10270.4 EGD98279.1 - 1e-28 99.8 0.0 1.2e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter DUF4612 PF15389.1 EGD98281.1 - 0.81 10.3 13.5 2.4 8.7 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) RNB PF00773.14 EGD98282.1 - 2.6e-77 260.2 0.1 2.3e-76 257.1 0.0 2.3 2 0 0 2 2 2 1 RNB domain BLVR PF06375.6 EGD98283.1 - 3.1 7.6 9.8 5.4 6.8 6.8 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Hid1 PF12722.2 EGD98284.1 - 2.9 5.4 16.9 3.3 5.2 11.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LMBR1 PF04791.11 EGD98284.1 - 3.8 5.9 14.2 38 2.6 9.8 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF3425 PF11905.3 EGD98285.1 - 1.3e-15 57.5 0.6 2.7e-15 56.4 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EGD98285.1 - 0.017 15.0 17.6 0.089 12.7 12.2 1.9 1 1 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 EGD98285.1 - 0.063 12.7 0.7 0.12 11.8 0.4 1.5 1 1 0 1 1 1 0 Septum formation initiator GBP_C PF02841.9 EGD98285.1 - 0.57 9.3 5.3 0.78 8.8 3.7 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Glyco_hydro_17 PF00332.13 EGD98287.1 - 9.7e-22 77.3 0.0 7.9e-21 74.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Myb_DNA-bind_6 PF13921.1 EGD98288.1 - 0.00015 21.7 1.4 0.0011 19.0 0.4 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD98288.1 - 0.0037 17.2 1.9 0.031 14.3 0.6 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF4194 PF13835.1 EGD98288.1 - 0.019 14.4 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) ANT PF03374.9 EGD98288.1 - 0.077 13.0 0.1 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain MADF_DNA_bdg PF10545.4 EGD98288.1 - 0.12 12.5 2.7 0.17 12.1 0.5 2.2 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GcrA PF07750.6 EGD98288.1 - 0.49 10.5 5.2 0.18 11.9 0.5 2.3 2 1 0 2 2 2 0 GcrA cell cycle regulator Totivirus_coat PF05518.6 EGD98288.1 - 2.5 5.8 6.8 3.4 5.3 4.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein FGF-BP1 PF06473.7 EGD98288.1 - 5.9 6.4 7.8 0.39 10.2 1.2 1.9 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) EMP24_GP25L PF01105.19 EGD98289.1 - 1.4e-45 155.2 0.1 1.7e-45 155.0 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NUDE_C PF04880.8 EGD98289.1 - 0.065 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PSI PF01437.20 EGD98290.1 - 2.7e-05 24.2 7.2 4.8e-05 23.4 5.0 1.5 1 0 0 1 1 1 1 Plexin repeat GRP PF07172.6 EGD98290.1 - 0.00058 20.2 8.7 0.00086 19.7 6.0 1.2 1 0 0 1 1 1 1 Glycine rich protein family P12 PF12669.2 EGD98290.1 - 0.0048 17.0 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 2 Virus attachment protein p12 family DUF1183 PF06682.7 EGD98290.1 - 0.012 15.2 0.2 0.014 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) GRA6 PF05084.8 EGD98290.1 - 0.12 11.8 1.3 0.18 11.2 0.9 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DUF533 PF04391.7 EGD98290.1 - 0.7 9.2 2.8 0.98 8.7 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF533) DUF3237 PF11578.3 EGD98291.1 - 1.4e-35 121.8 0.0 1.6e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Metallophos PF00149.23 EGD98292.1 - 1.1e-08 34.7 1.1 2.3e-08 33.7 0.8 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TilS_C PF11734.3 EGD98292.1 - 0.003 16.7 0.3 2.9 7.1 0.1 3.6 3 0 0 3 3 3 2 TilS substrate C-terminal domain TPR_6 PF13174.1 EGD98293.1 - 0.025 14.9 1.2 7.2 7.3 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat VWA_3 PF13768.1 EGD98296.1 - 4.9e-24 84.7 0.0 1.2e-23 83.5 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 EGD98296.1 - 6e-19 67.8 0.0 1.3e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EGD98296.1 - 2e-07 31.2 0.0 3.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EGD98296.1 - 2.2e-05 23.8 0.0 6.2e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 EGD98296.1 - 0.0051 15.9 0.0 0.0051 15.9 0.0 2.0 3 0 0 3 3 3 1 VWA domain containing CoxE-like protein DUF2201 PF09967.4 EGD98296.1 - 0.0081 16.1 0.0 0.041 13.9 0.0 2.1 2 0 0 2 2 2 1 VWA-like domain (DUF2201) CSTF_C PF14304.1 EGD98296.1 - 0.032 13.5 0.0 0.34 10.2 0.0 2.4 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal VWA PF00092.23 EGD98296.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain LANC_like PF05147.8 EGD98297.1 - 7.6e-28 97.0 0.0 2.3e-25 88.9 0.0 2.6 2 1 1 3 3 3 2 Lanthionine synthetase C-like protein CBF PF03914.12 EGD98298.1 - 3.1e-50 169.8 0.1 1.4e-49 167.7 0.1 2.2 1 0 0 1 1 1 1 CBF/Mak21 family Prok-E2_C PF14459.1 EGD98298.1 - 0.036 14.1 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family C tRNA-synt_2b PF00587.20 EGD98299.1 - 6.6e-32 110.4 0.0 1e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGD98299.1 - 5.3e-10 39.1 0.0 1.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain Prefoldin PF02996.12 EGD98300.1 - 1.4e-22 79.6 0.1 1.8e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4611 PF15387.1 EGD98301.1 - 0.065 13.3 2.4 0.19 11.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) KH_3 PF13014.1 EGD98301.1 - 0.093 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 KH domain CHCH PF06747.8 EGD98302.1 - 1.5e-06 27.9 11.0 4.6e-05 23.1 3.8 2.4 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 EGD98302.1 - 0.015 15.0 8.2 1.9 8.3 0.0 3.0 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like CAP PF00188.21 EGD98303.1 - 3.6e-16 59.7 8.8 4.8e-16 59.3 6.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Thioredox_DsbH PF03190.10 EGD98304.1 - 2e-69 232.5 0.0 5.1e-69 231.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EGD98304.1 - 1.5e-07 31.3 0.0 8.5e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like WD40 PF00400.27 EGD98305.1 - 7.8e-18 63.6 20.1 8.9e-06 25.4 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGD98305.1 - 0.026 13.2 0.0 0.11 11.2 0.0 1.9 2 1 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 EGD98305.1 - 0.079 11.0 0.1 0.17 9.9 0.1 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 DUF1902 PF08972.6 EGD98305.1 - 0.34 10.4 4.3 0.89 9.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) LSM14 PF12701.2 EGD98306.1 - 3.2e-32 110.2 0.0 8.3e-32 108.8 0.0 1.8 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EGD98306.1 - 1e-16 61.3 4.4 1e-16 61.3 3.1 3.2 3 1 0 3 3 3 1 FDF domain SM-ATX PF14438.1 EGD98306.1 - 0.022 14.6 0.0 0.064 13.1 0.0 1.8 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.6 EGD98306.1 - 0.27 9.7 15.0 0.21 10.0 5.6 2.1 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) ACBP PF00887.14 EGD98307.1 - 3.3e-28 97.1 0.0 1.1e-27 95.5 0.0 1.9 1 0 0 1 1 1 1 Acyl CoA binding protein CDC45 PF02724.9 EGD98307.1 - 0.069 11.1 2.1 0.081 10.9 1.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 EGD98307.1 - 0.13 10.0 2.2 0.16 9.7 1.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TraP PF07296.6 EGD98307.1 - 0.2 10.5 0.9 0.33 9.9 0.6 1.3 1 0 0 1 1 1 0 TraP protein DUF2890 PF11081.3 EGD98307.1 - 0.29 11.1 12.6 0.062 13.3 5.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) GP41 PF00517.12 EGD98307.1 - 0.84 9.1 6.1 0.059 12.9 0.7 1.6 2 0 0 2 2 2 0 Retroviral envelope protein DUF1754 PF08555.5 EGD98307.1 - 1.5 9.4 9.0 1.6 9.4 4.3 2.1 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) LZ_Tnp_IS66 PF13007.2 EGD98307.1 - 3.3 8.4 8.9 2.2 8.9 4.7 1.9 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain Glyco_transf_15 PF01793.11 EGD98308.1 - 1.6e-138 461.1 8.2 1.9e-138 460.9 5.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 EGD98309.1 - 1.1e-61 208.7 8.6 1.6e-61 208.2 6.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EGD98309.1 - 0.00016 19.9 1.2 0.00045 18.4 0.3 2.1 2 1 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 GATase_5 PF13507.1 EGD98310.1 - 1.2e-94 316.0 0.0 2.1e-94 315.2 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EGD98310.1 - 1.1e-44 152.1 0.3 3.9e-21 75.6 0.1 2.6 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EGD98310.1 - 7.3e-27 93.4 0.1 1.2e-25 89.5 0.0 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain MFS_1 PF07690.11 EGD98311.1 - 2e-44 151.7 28.8 2e-44 151.7 20.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD98311.1 - 1e-06 27.3 3.3 1.7e-06 26.5 2.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.4 EGD98311.1 - 0.0081 15.8 0.4 0.038 13.7 0.3 2.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2178) Herpes_US9 PF06072.6 EGD98311.1 - 1.6 8.6 4.3 14 5.5 0.4 3.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 zf-C3H1 PF10650.4 EGD98312.1 - 2.5e-07 30.0 0.3 3.9e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain DUF4091 PF13320.1 EGD98312.1 - 0.41 10.5 1.7 0.91 9.4 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) Myosin_head PF00063.16 EGD98313.1 - 8.2e-247 820.6 0.4 3.7e-246 818.5 0.0 2.5 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EGD98313.1 - 1.3e-30 105.9 271.9 4.4e-23 80.9 51.9 6.1 3 2 2 5 5 5 4 Myosin tail Myosin_N PF02736.14 EGD98313.1 - 0.00011 21.7 0.0 0.0003 20.3 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ADIP PF11559.3 EGD98313.1 - 0.00029 20.7 12.5 0.00029 20.7 8.7 17.8 5 4 13 20 20 20 4 Afadin- and alpha -actinin-Binding AAA_19 PF13245.1 EGD98313.1 - 0.068 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 EGD98313.1 - 2.2 7.3 81.8 0.29 10.2 4.2 9.4 4 3 3 9 9 9 0 Reovirus sigma C capsid protein Isy1 PF06246.7 EGD98314.1 - 2.6e-86 289.1 0.0 3.5e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 Isy1-like splicing family MMR_HSR1 PF01926.18 EGD98315.1 - 9.4e-13 48.1 0.0 1.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGD98315.1 - 5.1e-05 22.5 0.0 8.9e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EGD98315.1 - 0.0008 18.7 0.3 0.0019 17.4 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_15 PF13175.1 EGD98315.1 - 0.0043 16.1 0.0 0.0061 15.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EGD98315.1 - 0.0052 16.4 0.1 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EGD98315.1 - 0.006 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD98315.1 - 0.01 16.6 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EGD98315.1 - 0.012 15.0 0.0 0.038 13.4 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 EGD98315.1 - 0.029 14.8 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 EGD98315.1 - 0.032 14.3 0.0 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EGD98315.1 - 0.037 12.7 0.1 0.059 12.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 EGD98315.1 - 0.061 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 NTPase Arf PF00025.16 EGD98315.1 - 0.084 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Septin PF00735.13 EGD98315.1 - 0.13 11.2 0.0 0.3 10.0 0.0 1.6 2 0 0 2 2 2 0 Septin HCO3_cotransp PF00955.16 EGD98316.1 - 1.7e-49 168.8 16.9 6.1e-27 94.4 1.8 2.1 1 1 1 2 2 2 2 HCO3- transporter family PI3Ka PF00613.15 EGD98317.1 - 2.4e-59 199.6 0.2 3.7e-59 199.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EGD98317.1 - 2.4e-43 148.2 0.0 1.6e-41 142.3 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EGD98317.1 - 7.5e-29 100.3 0.0 1.2e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.5 EGD98318.1 - 5.7e-32 109.6 0.0 2.1e-31 107.8 0.0 2.0 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EGD98318.1 - 2.7e-17 62.3 0.1 1e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE Aida_N PF08910.5 EGD98318.1 - 0.11 12.7 0.3 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Aida N-terminus DUF3776 PF12618.3 EGD98318.1 - 2 8.9 9.5 36 4.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3776) DUF4336 PF14234.1 EGD98319.1 - 1.9e-14 53.5 0.1 2.6e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) DUF386 PF04074.7 EGD98319.1 - 0.095 12.2 0.0 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF386) MARVEL PF01284.18 EGD98320.1 - 5.6e-10 39.2 11.2 8.8e-10 38.5 7.7 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF202 PF02656.10 EGD98320.1 - 0.27 11.4 3.1 0.74 10.0 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) ThiF PF00899.16 EGD98322.1 - 4.4e-36 123.7 0.0 7.7e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family Glyco_hydro_17 PF00332.13 EGD98322.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 TrkA_N PF02254.13 EGD98322.1 - 0.014 15.4 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EGD98322.1 - 0.024 14.0 0.1 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CRISPR_assoc PF08798.6 EGD98322.1 - 0.054 13.2 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Saccharop_dh PF03435.13 EGD98322.1 - 0.058 12.3 1.4 0.32 9.9 0.9 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase DAO PF01266.19 EGD98322.1 - 0.063 12.1 0.2 0.19 10.6 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EGD98322.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EGD98322.1 - 0.13 11.5 0.1 0.42 9.9 0.1 1.8 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 EGD98322.1 - 0.2 10.4 0.4 0.36 9.6 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Clathrin PF00637.15 EGD98323.1 - 1.4e-18 66.9 0.0 6e-18 64.8 0.0 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 EGD98323.1 - 6.7e-07 28.9 1.9 0.24 11.3 0.0 4.4 4 1 0 4 4 4 2 WD domain, G-beta repeat zf-RING_5 PF14634.1 EGD98323.1 - 0.0058 16.3 0.2 0.0058 16.3 0.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Vps39_1 PF10366.4 EGD98323.1 - 0.13 12.3 0.2 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-RING_2 PF13639.1 EGD98323.1 - 0.19 11.5 4.4 0.086 12.6 0.8 2.2 2 0 0 2 2 2 0 Ring finger domain Coatomer_WDAD PF04053.9 EGD98323.1 - 0.46 9.2 0.1 4.3 6.0 0.0 2.0 2 0 0 2 2 2 0 Coatomer WD associated region BUD22 PF09073.5 EGD98323.1 - 1.3 8.0 6.7 2.4 7.1 4.7 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EGD98323.1 - 2.1 6.1 6.9 4.1 5.2 4.8 1.3 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 EGD98323.1 - 8.7 6.1 10.6 0.75 9.5 3.2 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF155 PF02582.9 EGD98324.1 - 2.4e-44 151.3 0.0 3.6e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 zf-H2C2_2 PF13465.1 EGD98325.1 - 7.8e-12 44.8 5.5 3.5e-05 23.8 0.1 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EGD98325.1 - 2.9e-07 30.4 17.9 0.00082 19.5 3.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD98325.1 - 4.4e-05 23.5 13.1 0.031 14.5 1.7 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGD98325.1 - 0.0086 15.9 7.7 0.24 11.3 1.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 EGD98325.1 - 0.23 11.2 7.6 0.19 11.5 3.6 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 EGD98325.1 - 8.2 6.7 8.6 0.59 10.3 1.5 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ubiquitin PF00240.18 EGD98326.1 - 1.7e-34 117.0 1.1 2.8e-34 116.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EGD98326.1 - 7.5e-28 96.1 1.9 1.6e-27 95.0 1.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EGD98326.1 - 7.9e-20 70.3 0.8 1.4e-19 69.5 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGD98326.1 - 9.6e-06 25.7 0.2 4.3e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGD98326.1 - 0.00016 21.4 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EGD98326.1 - 0.00077 19.3 0.5 0.0017 18.2 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGD98326.1 - 0.0035 17.4 0.5 0.0048 17.0 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 EGD98326.1 - 0.0091 15.8 0.5 0.015 15.1 0.4 1.3 1 0 0 1 1 1 1 IBR domain DUF2207 PF09972.4 EGD98326.1 - 0.038 12.5 0.3 0.041 12.4 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2870 PF11069.3 EGD98326.1 - 0.064 13.2 0.2 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EGD98326.1 - 0.13 10.5 2.3 2.3 6.4 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Glyco_hydro_18 PF00704.23 EGD98327.1 - 2.5e-97 326.4 4.0 2.9e-97 326.2 2.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PTR2 PF00854.16 EGD98328.1 - 2.6e-49 167.9 15.6 1.3e-48 165.7 10.8 2.0 1 1 0 1 1 1 1 POT family DUF3619 PF12279.3 EGD98329.1 - 0.03 14.3 0.8 0.052 13.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Proteasome PF00227.21 EGD98330.1 - 9.6e-48 161.9 0.0 1.3e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGD98330.1 - 5.1e-13 48.0 0.3 9e-13 47.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SCP2 PF02036.12 EGD98330.1 - 0.03 14.6 0.0 0.076 13.3 0.0 1.6 2 0 0 2 2 2 0 SCP-2 sterol transfer family DUF3650 PF12368.3 EGD98330.1 - 0.85 9.1 3.6 0.41 10.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) DUF2373 PF10180.4 EGD98331.1 - 5.7e-22 77.0 0.0 1.1e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) ATP_sub_h PF10775.4 EGD98331.1 - 0.78 9.5 6.7 4.5 7.0 1.3 2.6 2 0 0 2 2 2 0 ATP synthase complex subunit h Spc97_Spc98 PF04130.8 EGD98332.1 - 4.5e-117 391.6 0.0 6.6e-117 391.0 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family FSA_C PF10479.4 EGD98332.1 - 0.15 10.0 0.0 0.23 9.4 0.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Pkinase PF00069.20 EGD98334.1 - 2.7e-63 213.5 0.0 4e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98334.1 - 3.2e-43 147.6 0.0 4.9e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD98334.1 - 1.2e-09 37.5 0.0 1e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EGD98334.1 - 0.0032 16.5 0.0 0.006 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RepL PF05732.6 EGD98334.1 - 0.048 12.8 0.1 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) WTF PF03303.8 EGD98334.1 - 3.6 6.9 4.2 2.9 7.2 0.1 2.2 2 0 0 2 2 2 0 WTF protein Rad9 PF04139.8 EGD98335.1 - 1.3e-57 194.8 0.0 1.5e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EGD98335.1 - 0.0004 19.2 0.0 0.0025 16.6 0.0 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 RCC1 PF00415.13 EGD98336.1 - 7.8e-34 115.6 6.3 2.6e-07 30.7 0.4 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGD98336.1 - 6.6e-18 63.8 19.7 4.3e-07 29.3 0.2 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Mannitol_dh_C PF08125.8 EGD98337.1 - 5e-46 156.8 0.0 6.6e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EGD98337.1 - 1.5e-07 31.4 2.0 2e-07 31.0 0.6 1.8 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain Sec34 PF04136.10 EGD98339.1 - 1e-28 100.0 0.1 2.7e-28 98.6 0.1 1.7 1 0 0 1 1 1 1 Sec34-like family SYCE1 PF15233.1 EGD98339.1 - 0.1 12.5 0.1 0.84 9.5 0.0 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 NifW PF03206.9 EGD98339.1 - 0.21 11.7 1.1 12 6.0 0.0 3.1 3 0 0 3 3 3 0 Nitrogen fixation protein NifW Trypsin_2 PF13365.1 EGD98340.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain Pkinase PF00069.20 EGD98342.1 - 1.3e-14 54.0 0.0 2.5e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98342.1 - 6e-11 41.9 0.0 2.9e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD98342.1 - 0.22 10.4 0.0 0.42 9.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Aldose_epim PF01263.15 EGD98344.1 - 2.6e-48 164.6 0.2 3.4e-48 164.3 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase BRCT PF00533.21 EGD98344.1 - 0.069 13.3 0.1 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Rogdi_lz PF10259.4 EGD98345.1 - 0.088 11.8 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Actin PF00022.14 EGD98346.1 - 9.7e-25 86.7 0.0 2.5e-21 75.5 0.0 2.3 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EGD98346.1 - 0.089 11.3 0.0 0.3 9.6 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein XPG_I PF00867.13 EGD98347.1 - 1.2e-21 76.5 0.1 2.8e-21 75.3 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGD98347.1 - 7.5e-08 32.5 0.0 1.8e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain CTP_transf_1 PF01148.15 EGD98348.1 - 4.8e-15 55.9 7.3 6.7e-15 55.4 5.1 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family DEAD PF00270.24 EGD98349.1 - 1.6e-35 122.0 0.0 7.2e-35 119.9 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGD98349.1 - 1.6e-19 69.2 0.0 3.2e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGD98349.1 - 2e-19 69.2 0.0 8e-19 67.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD98349.1 - 0.0022 17.8 0.2 0.014 15.2 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGD98349.1 - 0.022 14.5 0.2 0.1 12.3 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EGD98349.1 - 0.078 13.1 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ribosomal_S15 PF00312.17 EGD98351.1 - 1.7e-15 56.4 1.0 5.6e-15 54.8 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_S2 PF00318.15 EGD98352.1 - 1.5e-42 145.2 0.0 1.5e-21 76.5 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Amidoligase_2 PF12224.3 EGD98353.1 - 3e-11 43.4 0.1 5.6e-10 39.2 0.0 2.1 1 1 0 1 1 1 1 Putative amidoligase enzyme PseudoU_synth_1 PF01416.15 EGD98354.1 - 5.6e-29 100.6 0.0 3.6e-22 78.7 0.0 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase PIG-H PF10181.4 EGD98355.1 - 1.6e-27 94.9 0.9 2.6e-27 94.2 0.1 1.8 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component ubiquitin PF00240.18 EGD98356.1 - 0.00051 19.3 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF1777 PF08648.7 EGD98356.1 - 0.003 17.3 43.3 0.0044 16.7 30.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) YukD PF08817.5 EGD98356.1 - 0.05 14.1 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD MIP-T3 PF10243.4 EGD98356.1 - 2.8 6.3 23.9 3.5 5.9 16.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pribosyl_synth PF14572.1 EGD98357.1 - 6.7e-41 140.0 2.4 1.9e-36 125.5 0.6 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EGD98357.1 - 9.5e-33 112.3 0.0 3.1e-32 110.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EGD98357.1 - 5.4e-11 42.3 0.1 1.4e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGD98357.1 - 0.00016 20.9 0.2 0.00026 20.2 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase vATP-synt_AC39 PF01992.11 EGD98358.1 - 6.1e-110 367.5 0.0 6.9e-110 367.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.13 EGD98359.1 - 4.3e-55 185.1 0.6 1e-54 183.9 0.4 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGD98359.1 - 3.2e-27 94.1 0.1 5.6e-27 93.3 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGD98359.1 - 7.6e-22 77.2 1.1 7.6e-22 77.2 0.8 3.0 3 0 0 3 3 3 1 NOP5NT (NUC127) domain Orexin_rec2 PF03827.8 EGD98359.1 - 0.082 12.9 0.3 0.88 9.6 0.0 2.4 2 0 0 2 2 2 0 Orexin receptor type 2 RNA_pol_Rpb4 PF03874.11 EGD98360.1 - 1.7e-07 31.2 0.4 0.0052 16.7 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb4 COG7 PF10191.4 EGD98361.1 - 0.026 12.4 0.0 0.064 11.1 0.0 1.6 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) PARP PF00644.15 EGD98363.1 - 7.4e-11 41.8 0.3 1.4e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EGD98363.1 - 2.4e-08 33.5 0.0 4.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGD98363.1 - 0.0024 17.7 0.1 0.0072 16.2 0.0 1.8 2 0 0 2 2 2 1 RWD domain Prok-E2_B PF14461.1 EGD98363.1 - 0.086 12.6 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B Aft1_HRA PF11786.3 EGD98364.1 - 8.8e-22 77.1 12.5 8.8e-22 77.1 8.6 2.8 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.3 EGD98364.1 - 1.4e-17 64.4 2.3 1.4e-17 64.4 1.6 4.6 2 1 1 4 4 4 1 Aft1 HRR domain Aft1_OSA PF11785.3 EGD98364.1 - 1.3e-10 41.6 3.3 1.3e-10 41.6 2.3 2.9 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 EGD98364.1 - 4.1e-08 33.0 10.9 6.9e-08 32.3 7.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGD98364.1 - 0.00067 19.4 9.8 0.0013 18.5 6.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EGD98364.1 - 0.038 14.2 4.7 0.074 13.3 3.2 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor TMF_DNA_bd PF12329.3 EGD98364.1 - 3.6 7.4 7.3 0.25 11.1 1.3 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Transthyretin PF00576.16 EGD98365.1 - 5e-20 71.4 0.0 2.3e-11 43.5 0.0 2.1 2 0 0 2 2 2 2 HIUase/Transthyretin family NAD_binding_6 PF08030.7 EGD98366.1 - 2.3e-17 63.3 0.0 3.4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGD98366.1 - 0.00023 20.9 0.0 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 EGD98366.1 - 0.0021 18.6 0.0 0.36 11.4 0.0 2.3 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain Ferric_reduct PF01794.14 EGD98367.1 - 6.9e-14 52.0 17.7 6.8e-13 48.7 12.2 2.4 1 1 0 1 1 1 1 Ferric reductase like transmembrane component ArsA_ATPase PF02374.10 EGD98368.1 - 8.6e-114 379.6 0.0 9.9e-114 379.4 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EGD98368.1 - 8.5e-17 61.2 0.1 1.3e-16 60.5 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGD98368.1 - 3.1e-08 33.7 0.0 2.1e-05 24.5 0.0 3.2 3 1 1 4 4 4 1 AAA domain Fer4_NifH PF00142.13 EGD98368.1 - 5.9e-06 25.6 0.1 1.3e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EGD98368.1 - 1.5e-05 24.5 0.3 0.00051 19.5 0.0 2.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain MipZ PF09140.6 EGD98368.1 - 0.018 14.1 0.1 0.054 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase MipZ YhjQ PF06564.7 EGD98368.1 - 0.025 13.9 0.0 0.063 12.6 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein PhoH PF02562.11 EGD98368.1 - 0.041 13.1 0.0 0.095 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 EGD98368.1 - 0.043 12.6 0.0 0.082 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 EGD98368.1 - 0.043 13.2 0.2 0.12 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGD98368.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EGD98368.1 - 0.1 12.3 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain eIF3_N PF09440.5 EGD98371.1 - 1.3e-47 161.2 2.2 3.1e-47 160.0 1.5 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EGD98371.1 - 9.3e-14 51.6 0.1 3e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EGD98371.1 - 0.0069 16.1 0.0 0.022 14.5 0.0 1.8 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 Img2 PF05046.9 EGD98372.1 - 3.4e-27 94.4 0.0 5.1e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.16 EGD98373.1 - 4e-17 61.8 0.0 1.3e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.20 EGD98375.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF504 PF04457.7 EGD98375.1 - 0.055 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF504) R3H PF01424.17 EGD98376.1 - 8.7e-12 44.5 0.0 7.5e-11 41.5 0.1 2.3 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.12 EGD98376.1 - 1e-05 25.3 57.6 0.00038 20.3 12.6 13.6 14 1 0 14 14 14 7 NF-X1 type zinc finger zf-LYAR PF08790.6 EGD98377.1 - 1.8e-14 53.1 3.8 4.3e-14 51.9 2.6 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Evr1_Alr PF04777.8 EGD98378.1 - 2.8e-11 43.1 0.0 4.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family MFS_1 PF07690.11 EGD98379.1 - 6.8e-20 71.0 60.2 1.2e-17 63.6 38.2 3.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD98379.1 - 1.2e-08 33.7 29.8 1.4e-08 33.4 10.9 2.2 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGD98379.1 - 1.3e-05 23.9 38.9 4.3e-05 22.2 11.0 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGD98380.1 - 2.6e-47 161.2 36.5 2.6e-47 161.2 25.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD98380.1 - 9e-11 41.0 10.1 9e-11 41.0 7.0 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EGD98380.1 - 3.1e-06 25.6 1.8 3.1e-06 25.6 1.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pho86 PF11124.3 EGD98380.1 - 0.045 12.7 0.5 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 GFA PF04828.9 EGD98381.1 - 1.6e-11 43.9 0.9 1.4e-06 28.1 0.0 2.2 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Acetyltransf_1 PF00583.19 EGD98382.1 - 1.1e-06 28.5 0.0 1.8e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD98382.1 - 8.4e-06 25.8 0.0 1.5e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD98382.1 - 1.1e-05 25.5 0.0 0.0002 21.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD98382.1 - 8.3e-05 22.4 0.1 0.00037 20.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EGD98382.1 - 0.0072 16.2 0.0 0.081 12.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD98382.1 - 0.036 13.8 0.0 0.36 10.6 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_1 PF00583.19 EGD98383.1 - 0.019 14.9 0.0 0.11 12.5 0.0 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD98383.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD98383.1 - 0.027 14.3 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD98383.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S10 PF00450.17 EGD98384.1 - 3.9e-82 276.6 0.0 5.6e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase PTCB-BRCT PF12738.2 EGD98385.1 - 2.5e-13 49.6 0.0 4.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EGD98385.1 - 4.7e-08 33.0 0.0 8.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 EGD98385.1 - 0.00088 18.9 0.0 0.0025 17.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 EGD98385.1 - 0.0017 18.4 0.0 0.0045 17.0 0.0 1.8 1 1 0 1 1 1 1 Fibronectin type III domain DUF605 PF04652.11 EGD98385.1 - 2.2 7.5 17.6 3.4 6.9 12.2 1.3 1 0 0 1 1 1 0 Vta1 like ERCC4 PF02732.10 EGD98386.1 - 1.3e-23 83.3 0.0 8.8e-23 80.6 0.0 2.4 2 0 0 2 2 2 1 ERCC4 domain eIF-1a PF01176.14 EGD98387.1 - 1.2e-28 98.2 0.1 1.7e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.18 EGD98389.1 - 1.3e-28 98.9 0.0 2e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EGD98389.1 - 0.0045 16.5 1.7 0.016 14.7 0.1 2.5 2 0 0 2 2 2 1 WH2 motif CorA PF01544.13 EGD98390.1 - 5.3e-09 35.5 0.0 8.8e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UPF0104 PF03706.8 EGD98390.1 - 0.045 13.0 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) CAP59_mtransfer PF11735.3 EGD98392.1 - 2.4e-67 226.6 0.0 3.6e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 SEN1_N PF12726.2 EGD98393.1 - 6.1e-217 722.1 6.2 8.1e-217 721.7 4.3 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EGD98393.1 - 2.4e-68 230.2 2.1 2.4e-68 230.2 1.4 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EGD98393.1 - 7.5e-61 205.0 0.0 1.6e-60 203.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGD98393.1 - 1e-11 44.4 0.1 3.8e-11 42.5 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGD98393.1 - 7.2e-09 35.4 0.1 1e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 EGD98393.1 - 1.1e-07 31.4 2.0 8.3e-06 25.3 0.1 3.1 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EGD98393.1 - 1.2e-07 31.4 0.1 0.012 15.1 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase zf-CCHC PF00098.18 EGD98393.1 - 0.00025 20.8 8.8 0.0067 16.3 0.7 2.9 2 0 0 2 2 2 2 Zinc knuckle T2SE PF00437.15 EGD98393.1 - 0.005 15.7 0.0 0.013 14.3 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EGD98393.1 - 0.0054 16.5 0.0 0.026 14.3 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCHC_5 PF14787.1 EGD98393.1 - 0.0054 16.1 7.5 0.18 11.3 0.1 2.8 1 1 1 2 2 2 2 GAG-polyprotein viral zinc-finger AAA_22 PF13401.1 EGD98393.1 - 0.037 14.1 0.8 5.6 7.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.1 EGD98393.1 - 0.059 12.7 0.0 0.18 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGD98393.1 - 0.18 12.1 4.6 0.053 13.8 0.3 2.3 2 0 0 2 2 2 0 AAA domain HAD PF12710.2 EGD98394.1 - 8.5e-13 48.9 0.1 1.9e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGD98394.1 - 1.6e-12 46.9 0.0 4.6e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGD98394.1 - 1.3e-11 45.3 1.0 1.6e-09 38.5 0.7 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD98394.1 - 0.00078 19.3 0.1 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGD98394.1 - 0.02 14.4 0.2 0.048 13.2 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase vATP-synt_E PF01991.13 EGD98397.1 - 2e-56 190.4 11.1 2.3e-56 190.2 7.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.1 EGD98397.1 - 0.014 15.4 5.4 6.8 6.8 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) Scaffolding_pro PF11418.3 EGD98397.1 - 1.2 9.4 5.4 0.68 10.2 1.3 2.1 2 0 0 2 2 2 0 Phi29 scaffolding protein Mg_trans_NIPA PF05653.9 EGD98398.1 - 9.6e-16 57.6 8.9 9.9e-10 37.8 0.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EGD98398.1 - 5.6e-06 26.4 1.2 5.6e-06 26.4 0.8 3.1 4 0 0 4 4 4 2 EamA-like transporter family UAA PF08449.6 EGD98398.1 - 0.0011 17.9 0.2 0.0022 16.9 0.1 1.4 1 0 0 1 1 1 1 UAA transporter family TMEM61 PF15105.1 EGD98398.1 - 0.021 14.3 0.1 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 TMEM61 protein family Multi_Drug_Res PF00893.14 EGD98398.1 - 0.021 15.2 5.4 0.068 13.6 0.1 2.8 2 0 0 2 2 2 0 Small Multidrug Resistance protein Lactonase PF10282.4 EGD98399.1 - 4.4e-85 285.7 0.0 5.4e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 EGD98399.1 - 0.11 12.4 0.0 0.99 9.3 0.0 2.6 3 0 0 3 3 3 0 WD domain, G-beta repeat SRF-TF PF00319.13 EGD98400.1 - 1.5e-23 81.7 0.2 2.2e-23 81.2 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 EGD98400.1 - 0.19 9.7 0.8 0.19 9.7 0.0 1.4 2 0 0 2 2 2 0 CDC45-like protein Tetraspannin PF00335.15 EGD98401.1 - 1e-08 34.7 3.1 1.4e-08 34.3 2.2 1.1 1 0 0 1 1 1 1 Tetraspanin family HGWP PF03578.10 EGD98401.1 - 0.53 9.6 2.9 1.8 7.9 1.7 2.1 2 0 0 2 2 2 0 HGWP repeat PepSY_TM_2 PF13703.1 EGD98401.1 - 0.56 10.4 4.3 0.86 9.8 0.5 2.6 3 0 0 3 3 3 0 PepSY-associated TM helix PGPGW PF09656.5 EGD98401.1 - 0.74 9.1 4.7 0.44 9.8 0.2 2.4 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) YjgP_YjgQ PF03739.9 EGD98401.1 - 4 6.0 5.9 0.32 9.6 0.6 1.6 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family DZR PF12773.2 EGD98402.1 - 0.16 11.8 2.2 14 5.5 0.1 2.6 2 1 0 2 2 2 0 Double zinc ribbon Acetyltransf_1 PF00583.19 EGD98403.1 - 0.00031 20.7 0.0 0.04 13.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family NAD_binding_6 PF08030.7 EGD98404.1 - 1.2e-19 70.7 0.0 4.1e-19 69.0 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGD98404.1 - 3e-16 59.2 0.0 6.6e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGD98404.1 - 3.1e-16 59.5 9.3 3.1e-16 59.5 6.4 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EGD98404.1 - 0.0018 18.8 0.0 2.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 EGD98404.1 - 0.15 12.1 10.7 0.21 11.7 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) RNase_PH PF01138.16 EGD98405.1 - 2.9e-17 63.2 0.7 1.3e-15 57.8 0.5 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_A22B PF04258.8 EGD98406.1 - 5e-38 131.2 0.0 1.5e-37 129.6 0.0 1.7 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EGD98406.1 - 4.2e-05 22.8 3.4 0.00015 20.9 2.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) Pro_isomerase PF00160.16 EGD98407.1 - 3.4e-52 176.7 0.0 3.8e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GDI PF00996.13 EGD98408.1 - 5.2e-40 137.0 0.0 7e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor B9-C2 PF07162.6 EGD98408.1 - 0.021 14.6 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein DUF604 PF04646.7 EGD98409.1 - 3.6e-07 29.6 0.0 5.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EGD98409.1 - 0.00069 18.9 0.0 0.0018 17.5 0.0 1.6 1 1 0 1 1 1 1 Fringe-like Phospholip_A2_3 PF09056.6 EGD98411.1 - 2.4e-36 124.3 3.9 2.9e-36 124.0 2.7 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 zf-C2HC5 PF06221.8 EGD98412.1 - 7.8e-20 70.3 5.6 1.3e-19 69.7 3.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Hexokinase_2 PF03727.11 EGD98413.1 - 2.2e-67 226.8 0.0 2.9e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EGD98413.1 - 6.6e-64 215.0 0.0 1.3e-63 214.0 0.0 1.5 1 0 0 1 1 1 1 Hexokinase Redoxin PF08534.5 EGD98414.1 - 9.5e-37 125.7 0.0 1.1e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGD98414.1 - 3.6e-13 49.2 0.0 4.4e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family POP1 PF06978.6 EGD98415.1 - 1.2e-64 217.4 15.0 2.4e-64 216.4 10.4 1.5 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EGD98415.1 - 3.2e-31 107.0 2.0 8.8e-31 105.6 1.4 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain DUF1690 PF07956.6 EGD98416.1 - 1.5e-29 102.8 1.9 3.4e-14 53.0 0.6 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Rootletin PF15035.1 EGD98416.1 - 0.053 13.4 3.4 0.13 12.1 0.2 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DAO PF01266.19 EGD98417.1 - 2.4e-18 66.1 0.0 3.6e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGD98417.1 - 0.012 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGD98417.1 - 0.017 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 EGD98419.1 - 2e-71 240.2 0.0 3.3e-71 239.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98419.1 - 4.8e-33 114.3 0.0 5.3e-32 110.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD98419.1 - 7.8e-06 25.0 0.0 1.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGD98419.1 - 0.00094 18.3 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD98419.1 - 0.0048 16.6 0.0 0.022 14.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD98419.1 - 0.12 11.8 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Zn_clus PF00172.13 EGD98420.1 - 6.8e-09 35.4 7.3 9.8e-09 34.9 5.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3328 PF11807.3 EGD98421.1 - 6.9e-18 65.1 0.5 1.1e-17 64.4 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_2 PF00891.13 EGD98422.1 - 6.8e-45 153.1 0.1 8.8e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGD98422.1 - 3.9e-07 29.9 0.0 7.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD98422.1 - 4e-06 27.3 0.1 3.4e-05 24.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain CheR PF01739.13 EGD98422.1 - 0.0013 18.0 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_31 PF13847.1 EGD98422.1 - 0.0091 15.5 0.0 0.052 13.1 0.0 2.2 3 1 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 EGD98422.1 - 0.034 13.5 0.0 0.079 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EGD98422.1 - 0.069 13.6 0.0 0.32 11.5 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain UDPG_MGDP_dh PF00984.14 EGD98422.1 - 0.13 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Myb_DNA-binding PF00249.26 EGD98423.1 - 1.7e-34 117.5 4.2 1.6e-11 44.0 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD98423.1 - 1.5e-31 108.2 8.1 3.6e-14 52.6 0.0 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGD98423.1 - 0.0022 18.0 10.8 0.15 12.1 0.1 3.9 3 2 0 3 3 3 2 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 EGD98423.1 - 0.0056 16.5 0.9 0.51 10.2 0.0 2.6 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.1 EGD98423.1 - 0.023 14.5 10.2 12 5.8 0.1 5.5 5 1 2 7 7 7 0 Myb/SANT-like DNA-binding domain FAD_binding_4 PF01565.18 EGD98424.1 - 1.1e-25 89.7 0.1 1.7e-25 89.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD98424.1 - 0.00047 19.9 0.1 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like PsbT PF01405.12 EGD98424.1 - 0.017 14.6 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre T protein adh_short PF00106.20 EGD98425.1 - 4.3e-27 95.0 0.4 4.7e-27 94.9 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD98425.1 - 3.2e-14 53.2 0.0 3.6e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD98425.1 - 4.5e-11 42.7 0.2 6.2e-11 42.2 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGD98425.1 - 2.4e-06 27.6 0.3 2.8e-06 27.4 0.2 1.3 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EGD98425.1 - 0.0015 18.3 0.1 0.0035 17.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 EGD98425.1 - 0.0059 15.6 0.4 0.0082 15.1 0.2 1.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase DUF1776 PF08643.5 EGD98425.1 - 0.0065 15.6 0.0 0.025 13.7 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) eIF-6 PF01912.13 EGD98425.1 - 0.01 14.9 0.1 0.18 10.9 0.1 2.0 2 0 0 2 2 2 0 eIF-6 family Epimerase PF01370.16 EGD98425.1 - 0.011 15.2 0.1 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KdpC PF02669.10 EGD98425.1 - 0.035 13.7 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain 3HCDH_N PF02737.13 EGD98425.1 - 0.047 13.3 0.2 0.067 12.8 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Telomere_Sde2_2 PF13297.1 EGD98425.1 - 0.069 12.4 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Telomere stability C-terminal AA_permease PF00324.16 EGD98426.1 - 1.3e-115 386.5 38.1 1.5e-115 386.3 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD98426.1 - 2e-29 102.3 42.4 2.6e-29 102.0 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3675 PF12428.3 EGD98426.1 - 2.3 8.5 4.8 5.4 7.3 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) HTH_23 PF13384.1 EGD98427.1 - 2.5e-06 26.9 0.2 6.4e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EGD98427.1 - 3.5e-06 27.1 0.7 7.6e-06 26.0 0.3 1.7 1 1 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.7 EGD98427.1 - 4.1e-05 22.9 0.1 0.00054 19.3 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Mucin PF01456.12 EGD98427.1 - 0.00011 22.0 6.3 0.00013 21.7 4.3 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein HTH_38 PF13936.1 EGD98427.1 - 0.00011 21.6 0.6 0.00011 21.6 0.4 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.10 EGD98427.1 - 0.00096 18.9 0.3 0.21 11.4 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase GerE PF00196.14 EGD98427.1 - 0.0025 17.0 0.0 0.0052 16.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_28 PF13518.1 EGD98427.1 - 0.0062 16.5 1.7 0.0062 16.5 1.2 2.4 3 1 0 3 3 2 1 Helix-turn-helix domain HTH_31 PF13560.1 EGD98427.1 - 0.0078 16.3 0.7 0.025 14.7 0.5 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 EGD98427.1 - 0.025 13.8 0.2 0.088 12.1 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_3 PF01381.17 EGD98427.1 - 0.085 12.7 0.7 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix HTH_Tnp_1 PF01527.15 EGD98427.1 - 0.089 12.7 0.6 0.39 10.7 0.1 2.3 2 1 0 2 2 2 0 Transposase DNA_binding_1 PF01035.15 EGD98427.1 - 0.093 12.4 0.1 5.5 6.8 0.0 2.3 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF3439 PF11921.3 EGD98427.1 - 5.5 6.7 10.8 11 5.7 7.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) KGG PF10685.4 EGD98428.1 - 1.2e-26 92.0 22.3 1.4e-11 43.9 2.0 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Aminotran_5 PF00266.14 EGD98429.1 - 1.3e-17 63.6 0.0 1.5e-16 60.1 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V UNC-93 PF05978.11 EGD98430.1 - 1.3e-05 24.7 2.2 1.3e-05 24.7 1.5 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 WD40 PF00400.27 EGD98431.1 - 2.7e-65 214.0 14.9 2.7e-13 49.2 0.4 8.3 8 1 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EGD98431.1 - 5.6e-08 31.3 0.0 0.045 11.8 0.0 4.2 2 2 1 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.7 EGD98431.1 - 0.0033 17.0 1.8 3.3 7.4 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.6 EGD98431.1 - 0.011 14.7 0.1 0.48 9.2 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Nbas_N PF15492.1 EGD98431.1 - 0.043 12.9 0.4 11 5.0 0.0 3.3 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 EGD98431.1 - 0.17 10.0 0.0 0.36 8.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Exo_endo_phos PF03372.18 EGD98432.1 - 1.6e-15 57.7 0.2 2.4e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thi4 PF01946.12 EGD98433.1 - 1.3e-99 331.9 0.0 1.6e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EGD98433.1 - 1.8e-07 30.3 0.1 2.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGD98433.1 - 2.7e-05 23.2 0.2 4.8e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGD98433.1 - 3e-05 23.9 0.1 0.00015 21.7 0.1 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGD98433.1 - 0.0012 18.6 0.1 0.0042 16.8 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGD98433.1 - 0.0047 16.8 0.1 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD98433.1 - 0.0076 16.3 0.0 0.0099 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGD98433.1 - 0.05 12.4 0.2 0.14 10.9 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EGD98433.1 - 0.061 12.3 0.1 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EGD98433.1 - 0.064 11.8 0.2 0.089 11.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 EGD98433.1 - 0.15 11.0 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ACC_epsilon PF13822.1 EGD98434.1 - 9.3 6.6 9.3 1.9 8.9 0.6 2.8 2 1 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Ppx-GppA PF02541.11 EGD98435.1 - 2.4e-39 135.2 0.0 1.7e-38 132.4 0.0 1.9 1 1 0 1 1 1 1 Ppx/GppA phosphatase family LINES_C PF14695.1 EGD98435.1 - 0.094 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Lines C-terminus Proteasome PF00227.21 EGD98436.1 - 5.1e-48 162.8 0.1 6.1e-48 162.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 EGD98436.1 - 0.087 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Pil1 PF13805.1 EGD98437.1 - 4e-85 285.2 0.2 5.1e-85 284.9 0.2 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3452 PF11934.3 EGD98437.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) SWI-SNF_Ssr4 PF08549.5 EGD98438.1 - 2e-221 736.9 13.5 2.2e-221 736.7 9.3 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) RNA_pol_Rpb2_6 PF00562.23 EGD98439.1 - 2.1e-116 388.8 0.0 2.8e-116 388.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGD98439.1 - 6.7e-34 116.5 0.0 9.5e-34 116.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGD98439.1 - 1.4e-27 96.3 0.0 2.5e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EGD98439.1 - 5.3e-24 83.7 0.0 1.1e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EGD98439.1 - 5.4e-24 83.8 0.1 1.5e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EGD98439.1 - 4.1e-15 55.7 0.0 2.9e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EGD98439.1 - 0.00046 20.1 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Acyl_transf_1 PF00698.16 EGD98441.1 - 3.5e-63 213.8 0.0 1.3e-62 212.0 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain ketoacyl-synt PF00109.21 EGD98441.1 - 1.1e-58 198.6 0.0 2.6e-58 197.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EGD98441.1 - 1.3e-55 187.9 0.0 5.8e-55 185.7 0.0 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EGD98441.1 - 1.6e-55 188.4 0.0 2.5e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGD98441.1 - 2.5e-43 147.8 0.5 1.1e-42 145.8 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EGD98441.1 - 5.8e-19 67.9 0.0 1.7e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EGD98441.1 - 2.4e-14 53.6 0.0 6e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ketoacyl-synt_C PF02801.17 EGD98441.1 - 1.5e-12 47.3 0.0 4.2e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_23 PF13489.1 EGD98441.1 - 2.4e-12 46.8 0.0 5.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGD98441.1 - 3.5e-12 47.3 0.0 1.4e-11 45.4 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EGD98441.1 - 8.4e-10 38.4 0.0 1.9e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD98441.1 - 7e-09 36.0 0.0 1.7e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD98441.1 - 3e-08 34.2 0.0 1.7e-07 31.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 EGD98441.1 - 1.6e-06 27.8 0.0 5.2e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 EGD98441.1 - 0.00015 21.0 0.0 0.00032 19.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EGD98441.1 - 0.00045 20.4 0.0 0.0017 18.6 0.0 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.4 EGD98441.1 - 0.0063 15.9 0.0 0.064 12.7 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EGD98441.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Rsm22 PF09243.5 EGD98441.1 - 0.065 12.2 0.0 0.17 10.8 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 Arf PF00025.16 EGD98442.1 - 1.3e-43 148.2 0.0 1.6e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGD98442.1 - 4.8e-20 71.5 0.0 5.4e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD98442.1 - 1.1e-10 42.0 0.0 1.9e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGD98442.1 - 1.1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGD98442.1 - 1.5e-06 27.5 0.0 1.8e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGD98442.1 - 1.9e-06 27.1 0.0 2.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EGD98442.1 - 3.1e-05 22.8 0.0 6.8e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 G-protein alpha subunit Dynamin_N PF00350.18 EGD98442.1 - 0.00029 20.6 0.1 0.01 15.6 0.1 2.2 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 EGD98442.1 - 0.028 13.7 0.3 0.079 12.2 0.0 1.8 2 1 0 2 2 2 0 Ferrous iron transport protein B RCR PF12273.3 EGD98443.1 - 6.5e-22 78.4 9.4 6.5e-22 78.4 6.5 1.6 2 0 0 2 2 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.1 EGD98443.1 - 2.7e-05 24.4 0.4 3.8e-05 23.9 0.3 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF1183 PF06682.7 EGD98443.1 - 0.00019 21.1 1.1 0.0002 21.0 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF2868 PF11067.3 EGD98443.1 - 0.0097 15.0 0.2 0.011 14.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2868) DUF4131 PF13567.1 EGD98443.1 - 0.011 15.1 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TMEM51 PF15345.1 EGD98443.1 - 0.012 15.3 0.1 0.019 14.6 0.1 1.3 1 1 0 1 1 1 0 Transmembrane protein 51 DUF4051 PF13260.1 EGD98443.1 - 0.023 14.0 1.9 0.037 13.3 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) DUF3328 PF11807.3 EGD98443.1 - 0.027 14.1 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Rhabdo_glycop PF00974.13 EGD98443.1 - 0.049 11.8 0.5 0.066 11.4 0.4 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Herpes_UL37_2 PF07413.6 EGD98443.1 - 0.063 12.0 0.0 0.076 11.7 0.0 1.1 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 SLAC1 PF03595.12 EGD98443.1 - 0.067 11.8 0.6 0.08 11.5 0.4 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel GP41 PF00517.12 EGD98443.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Tetraspannin PF00335.15 EGD98443.1 - 0.16 11.1 0.0 0.16 11.1 0.0 1.4 2 0 0 2 2 2 0 Tetraspanin family Herpes_UL73 PF03554.8 EGD98443.1 - 0.21 11.4 0.8 0.41 10.5 0.6 1.4 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein LSR PF05624.9 EGD98443.1 - 0.22 11.2 3.2 0.32 10.7 2.2 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) WBP-1 PF11669.3 EGD98443.1 - 4.9 7.2 7.0 12 6.0 4.9 1.7 1 1 0 1 1 1 0 WW domain-binding protein 1 PepSY_TM PF03929.11 EGD98443.1 - 8.9 6.9 7.6 49 4.6 5.3 2.1 1 1 0 1 1 1 0 PepSY-associated TM helix Corona_S2 PF01601.11 EGD98444.1 - 0.17 9.9 16.1 0.24 9.4 11.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Podoplanin PF05808.6 EGD98444.1 - 1.2 8.6 3.5 9.3 5.7 0.5 2.3 2 0 0 2 2 2 0 Podoplanin MFS_1 PF07690.11 EGD98445.1 - 1.2e-10 40.7 48.8 1.4e-10 40.4 25.9 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF106 PF01956.11 EGD98445.1 - 8.8 5.8 7.2 0.94 8.9 0.1 2.5 2 1 1 3 3 3 0 Integral membrane protein DUF106 CwfJ_C_1 PF04677.10 EGD98447.1 - 7.3e-25 86.9 0.0 1.2e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EGD98447.1 - 1e-24 86.8 0.2 2.2e-24 85.7 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Toxin_38 PF14866.1 EGD98447.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Potassium channel toxin DRIM PF07539.7 EGD98448.1 - 2.5e-41 140.3 0.0 1.3e-40 138.1 0.0 2.4 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 EGD98448.1 - 0.0085 16.0 7.5 1.5 9.1 0.0 6.6 8 0 0 8 8 8 1 HEAT repeat zf-DNL PF05180.7 EGD98449.1 - 1.1e-27 95.5 0.2 2.2e-27 94.5 0.2 1.5 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 EGD98449.1 - 0.00082 18.8 0.1 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 CSL zinc finger TFIIS_C PF01096.13 EGD98449.1 - 0.0074 15.8 1.0 1.1 8.8 0.1 2.4 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) Elf1 PF05129.8 EGD98449.1 - 0.077 12.6 0.3 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 EGD98449.1 - 0.38 10.4 2.3 0.69 9.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EGD98449.1 - 0.6 9.9 5.9 1.8 8.4 0.5 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGD98449.1 - 0.63 9.6 2.5 0.79 9.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain E7 PF00527.13 EGD98449.1 - 1.1 9.4 3.2 7.5 6.7 2.2 2.2 1 1 0 1 1 1 0 E7 protein, Early protein Cullin PF00888.17 EGD98450.1 - 1.7e-127 426.4 6.7 1.7e-127 426.4 4.6 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EGD98450.1 - 2.6e-28 97.6 0.7 1e-27 95.7 0.3 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF1737 PF08410.5 EGD98450.1 - 0.012 15.3 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Sld5 PF05916.6 EGD98451.1 - 0.0015 18.7 0.1 0.0021 18.3 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein Rhodanese PF00581.15 EGD98452.1 - 2.8e-13 50.2 0.0 5.5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DUF92 PF01940.11 EGD98453.1 - 0.0059 15.7 0.6 0.0074 15.4 0.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 NfeD PF01957.13 EGD98453.1 - 0.027 14.5 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF4050 PF13259.1 EGD98453.1 - 0.038 13.9 2.1 0.042 13.7 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) OAD_gamma PF04277.8 EGD98453.1 - 0.045 14.1 0.1 0.058 13.7 0.1 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Picorna_P3A PF06363.6 EGD98453.1 - 0.055 13.4 0.9 0.077 13.0 0.6 1.3 1 0 0 1 1 1 0 Picornaviridae P3A protein RSN1_TM PF13967.1 EGD98453.1 - 0.058 12.9 0.2 0.076 12.5 0.2 1.1 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport BatD PF13584.1 EGD98453.1 - 0.064 11.8 0.6 0.073 11.6 0.4 1.0 1 0 0 1 1 1 0 Oxygen tolerance TRM13 PF05206.9 EGD98453.1 - 0.075 12.2 0.8 0.079 12.1 0.6 1.1 1 0 0 1 1 1 0 Methyltransferase TRM13 EphA2_TM PF14575.1 EGD98453.1 - 0.097 13.0 0.6 0.12 12.7 0.4 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OSTbeta PF15048.1 EGD98453.1 - 0.1 12.6 0.5 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Conotoxin PF02950.12 EGD98453.1 - 0.16 12.8 0.9 0.31 11.8 0.6 1.6 1 1 0 1 1 1 0 Conotoxin TMEM154 PF15102.1 EGD98453.1 - 0.16 11.6 0.1 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.6 EGD98453.1 - 0.21 11.2 1.2 0.21 11.1 0.8 1.2 1 0 0 1 1 1 0 Protocadherin TMEMspv1-c74-12 PF11044.3 EGD98453.1 - 0.22 11.1 5.5 0.46 10.0 3.8 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein SART-1 PF03343.8 EGD98453.1 - 0.82 7.9 10.7 0.95 7.7 7.4 1.0 1 0 0 1 1 1 0 SART-1 family Gon7 PF08738.5 EGD98453.1 - 2.3 8.2 6.3 3.9 7.5 4.4 1.3 1 0 0 1 1 1 0 Gon7 family YajC PF02699.10 EGD98453.1 - 2.7 7.7 8.2 18 5.0 5.7 2.0 1 1 0 1 1 1 0 Preprotein translocase subunit DUF1049 PF06305.6 EGD98453.1 - 6.8 6.2 7.6 1.3 8.5 2.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Iso_dh PF00180.15 EGD98454.1 - 2.8e-83 279.7 0.0 3.3e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DNA_pol_phi PF04931.8 EGD98455.1 - 1.9e-68 231.0 16.6 1.9e-61 207.9 11.5 2.2 2 0 0 2 2 2 2 DNA polymerase phi TPT PF03151.11 EGD98456.1 - 8.2e-29 100.2 13.7 8.2e-29 100.2 9.5 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EGD98456.1 - 0.00012 21.1 23.1 0.00012 21.1 16.0 1.9 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.15 EGD98456.1 - 0.013 15.5 38.6 0.018 15.0 9.8 3.1 2 2 1 3 3 3 0 EamA-like transporter family UcrQ PF02939.11 EGD98456.1 - 0.05 13.4 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 UcrQ family AD PF09793.4 EGD98457.1 - 6e-24 83.7 0.1 1.6e-23 82.3 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain Menin PF05053.8 EGD98457.1 - 0.16 10.1 2.0 0.21 9.7 1.4 1.2 1 0 0 1 1 1 0 Menin RRM_1 PF00076.17 EGD98458.1 - 5.7e-18 64.3 0.0 9.3e-18 63.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD98458.1 - 1.7e-10 40.6 0.0 3.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD98458.1 - 0.001 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EGD98458.1 - 0.15 11.5 0.2 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain 6PGD PF00393.14 EGD98459.1 - 4.2e-118 393.7 0.0 5.3e-115 383.6 0.0 2.1 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGD98459.1 - 3e-51 173.5 0.0 4.3e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGD98459.1 - 0.074 13.1 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 EGD98459.1 - 0.13 12.3 0.1 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Esterase_phd PF10503.4 EGD98459.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase DNA_pol3_beta PF00712.14 EGD98459.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain Peptidase_C15 PF01470.12 EGD98460.1 - 2.7e-15 56.7 0.0 3.8e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Pyroglutamyl peptidase AA_permease PF00324.16 EGD98465.1 - 4.2e-110 368.3 38.2 5.2e-110 368.0 26.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD98465.1 - 3.5e-28 98.3 41.0 4.2e-28 98.0 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease HET PF06985.6 EGD98466.1 - 7.5e-26 90.9 1.0 2.2e-21 76.4 0.3 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EGD98466.1 - 3.5e-20 72.1 0.0 2.7e-10 40.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD98466.1 - 7.5e-08 32.3 0.1 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGD98466.1 - 1.3e-07 31.9 0.1 0.0017 18.7 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EGD98466.1 - 3.5e-07 29.7 0.0 0.0012 18.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EGD98466.1 - 0.0029 17.6 0.0 0.12 12.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat AP_endonuc_2 PF01261.19 EGD98467.1 - 3.1e-25 88.7 0.0 4.6e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.7 EGD98468.1 - 8.1e-44 148.4 0.7 1.7e-43 147.4 0.1 1.8 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EGD98468.1 - 2e-14 53.3 0.0 4.7e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_II PF08171.6 EGD98468.1 - 3.7e-05 23.5 0.0 0.00032 20.5 0.0 2.6 1 1 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.12 EGD98468.1 - 0.00052 19.1 0.0 0.0019 17.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase CDC45 PF02724.9 EGD98469.1 - 0.26 9.2 3.5 0.29 9.1 2.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGD98469.1 - 1.8 6.3 7.4 2.2 6.0 5.1 1.0 1 0 0 1 1 1 0 Nop14-like family Toxin_29 PF08116.6 EGD98469.1 - 4 7.2 7.0 7.2 6.4 0.5 2.7 2 0 0 2 2 2 0 PhTx neurotoxin family Hexokinase_2 PF03727.11 EGD98470.1 - 3.4e-25 88.6 0.0 3e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EGD98470.1 - 1.1e-24 86.9 0.0 1.6e-12 47.2 0.0 2.6 2 1 0 2 2 2 2 Hexokinase Lipoprotein_19 PF13617.1 EGD98470.1 - 0.2 11.2 1.7 0.49 10.0 0.3 2.1 2 0 0 2 2 2 0 YnbE-like lipoprotein DUF3237 PF11578.3 EGD98471.1 - 2.8e-07 29.9 0.0 3.3e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ADH_N PF08240.7 EGD98472.1 - 5.5e-21 74.3 1.8 1.2e-20 73.2 1.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD98472.1 - 0.0001 21.8 0.1 0.00036 20.0 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 EGD98474.1 - 2.2e-12 46.4 1.1 3.4e-12 45.7 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD98474.1 - 1.9e-09 37.2 9.5 3.9e-09 36.2 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mur_ligase_M PF08245.7 EGD98475.1 - 1.3e-08 35.1 0.7 1.5e-06 28.4 0.1 2.9 2 1 0 2 2 2 2 Mur ligase middle domain TPR_12 PF13424.1 EGD98476.1 - 9e-12 44.7 1.4 0.00033 20.5 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGD98476.1 - 2.6e-10 39.2 0.4 0.007 16.0 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD98476.1 - 3.8e-10 39.4 0.1 0.34 11.6 0.0 5.4 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD98476.1 - 6.5e-10 38.5 0.3 0.016 14.8 0.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EGD98476.1 - 8.2e-09 34.7 1.7 0.083 12.8 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGD98476.1 - 1.9e-08 34.4 0.0 0.036 14.3 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.17 EGD98476.1 - 4.9e-08 32.1 0.0 8.3e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.1 EGD98476.1 - 1.2e-06 27.8 5.2 0.43 10.4 0.1 4.9 6 0 0 6 6 4 3 Tetratricopeptide repeat DUF676 PF05057.9 EGD98476.1 - 3.6e-05 23.1 0.0 7.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGD98476.1 - 4.1e-05 23.2 0.0 0.00084 18.9 0.0 2.4 2 0 0 2 2 2 1 PGAP1-like protein TPR_1 PF00515.23 EGD98476.1 - 0.00016 21.1 0.5 0.64 9.7 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD98476.1 - 0.00021 21.3 0.0 0.51 10.4 0.0 3.1 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.1 EGD98476.1 - 0.00048 20.2 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.1 EGD98476.1 - 0.0032 18.1 0.2 35 5.2 0.0 4.2 4 1 0 4 4 3 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EGD98476.1 - 0.047 13.5 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPR_10 PF13374.1 EGD98476.1 - 0.048 13.5 0.0 31 4.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD98476.1 - 0.054 13.9 1.4 64 4.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_3 PF13812.1 EGD98476.1 - 0.096 13.0 0.2 40 4.8 0.0 4.2 4 0 0 4 4 3 0 Pentatricopeptide repeat domain Zot PF05707.7 EGD98476.1 - 0.14 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) TPR_17 PF13431.1 EGD98476.1 - 0.44 10.8 1.6 73 3.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 EGD98476.1 - 0.63 10.1 5.5 29 4.9 0.0 4.5 6 0 0 6 6 5 0 PPR repeat zf-UBR PF02207.15 EGD98477.1 - 2e-14 53.0 19.7 2e-14 53.0 13.6 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EGD98477.1 - 9.8e-05 22.0 0.0 0.00024 20.7 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UCR_UQCRX_QCR9 PF05365.7 EGD98478.1 - 3.2e-26 90.7 0.9 3.6e-26 90.5 0.7 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 EGD98479.1 - 2e-13 49.6 1.9 3.6e-13 48.8 1.3 1.4 1 0 0 1 1 1 1 Mago binding Mitofilin PF09731.4 EGD98479.1 - 0.075 11.6 11.3 0.083 11.5 7.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Amino_oxidase PF01593.19 EGD98480.1 - 2e-16 60.1 0.1 6.9e-16 58.3 0.1 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGD98480.1 - 1.8e-13 50.3 0.1 6.2e-13 48.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD98480.1 - 3.3e-08 32.8 0.1 1.7e-07 30.4 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGD98480.1 - 0.00028 20.1 0.3 0.00047 19.3 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGD98480.1 - 0.00038 20.2 0.0 0.0019 18.0 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGD98480.1 - 0.00057 19.8 0.1 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD98480.1 - 0.00092 17.7 0.1 0.0043 15.5 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EGD98480.1 - 0.0014 17.5 0.2 0.0025 16.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EGD98480.1 - 0.0015 18.9 0.1 0.097 13.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD98480.1 - 0.003 16.6 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EGD98480.1 - 0.0041 17.2 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGD98480.1 - 0.036 12.2 0.4 0.11 10.6 0.0 1.8 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like UDPG_MGDP_dh_N PF03721.9 EGD98480.1 - 0.13 11.6 0.1 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 EGD98480.1 - 0.13 11.0 0.1 0.75 8.5 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A zf-CCCH_2 PF14608.1 EGD98481.1 - 1e-06 28.5 51.1 4.1e-06 26.5 7.2 5.6 5 1 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EGD98481.1 - 0.0061 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Glyco_hydro_20 PF00728.17 EGD98482.1 - 4.7e-78 262.8 0.0 6e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EGD98482.1 - 2.6e-18 66.9 0.0 9e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EGD98482.1 - 0.00034 21.1 0.0 0.00085 19.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.17 EGD98483.1 - 1e-59 202.2 0.0 3.8e-43 147.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 2-Hacid_dh_C PF02826.14 EGD98485.1 - 1.8e-46 157.5 0.0 2.9e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD98485.1 - 9.9e-37 125.3 0.0 1.5e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 EGD98485.1 - 0.0067 16.7 0.0 0.023 15.0 0.0 1.9 2 0 0 2 2 2 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 EGD98485.1 - 0.01 15.3 1.9 0.56 9.7 0.7 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ACT PF01842.20 EGD98485.1 - 0.061 12.8 2.2 0.18 11.3 0.0 2.8 3 0 0 3 3 3 0 ACT domain Fe-ADH PF00465.14 EGD98486.1 - 5.4e-103 344.4 0.0 7.2e-103 344.0 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGD98486.1 - 4.2e-17 62.2 0.0 2e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EGD98486.1 - 0.00088 18.7 0.1 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Ank_2 PF12796.2 EGD98487.1 - 8.5e-81 266.3 14.3 2.5e-18 66.1 0.3 7.1 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EGD98487.1 - 2.1e-78 254.4 18.9 1.4e-09 37.2 0.0 12.1 12 0 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.1 EGD98487.1 - 1.4e-61 203.8 16.7 5.8e-12 45.7 0.1 8.4 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD98487.1 - 2.2e-58 188.3 17.1 1.1e-06 28.2 0.0 12.2 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.1 EGD98487.1 - 1.7e-50 167.9 18.8 8.9e-08 32.1 0.0 9.7 4 1 7 11 11 11 10 Ankyrin repeats (many copies) Saccharop_dh PF03435.13 EGD98487.1 - 0.028 13.4 0.5 3.8 6.3 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase DUF2370 PF10176.4 EGD98487.1 - 0.24 10.6 1.9 0.4 9.9 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Glyco_hydro_2_N PF02837.13 EGD98488.1 - 1.3e-09 37.8 0.0 2.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EGD98488.1 - 2.4e-09 37.6 0.6 5.6e-08 33.2 0.0 2.9 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 CARDB PF07705.6 EGD98488.1 - 0.12 12.4 0.1 0.39 10.7 0.1 1.8 1 0 0 1 1 1 0 CARDB DNA_circ_N PF07157.7 EGD98488.1 - 0.15 12.2 0.0 19 5.4 0.0 3.0 4 0 0 4 4 4 0 DNA circularisation protein N-terminus Kin17_mid PF10357.4 EGD98489.1 - 2.6e-46 156.3 1.5 2.6e-46 156.3 1.0 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EGD98489.1 - 1.7e-05 24.8 0.3 1.7e-05 24.8 0.2 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGD98489.1 - 1.7e-05 24.8 0.8 4.3e-05 23.5 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type MTBP_mid PF14919.1 EGD98489.1 - 0.0026 16.5 1.0 0.0035 16.0 0.7 1.2 1 0 0 1 1 1 1 MDM2-binding zf-C2H2_2 PF12756.2 EGD98489.1 - 0.013 15.5 3.2 0.017 15.2 0.3 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Glyoxalase PF00903.20 EGD98490.1 - 1.9e-37 128.0 0.1 3.1e-18 65.9 0.1 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGD98490.1 - 6.7e-31 107.0 0.1 2.8e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EGD98490.1 - 4.1e-18 65.3 0.0 4.5e-08 33.0 0.0 3.8 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EGD98490.1 - 6.4e-07 29.4 0.0 0.019 14.8 0.0 2.9 2 1 1 3 3 3 2 Glyoxalase-like domain CppA_N PF14506.1 EGD98490.1 - 0.12 12.0 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 CppA N-terminal PH PF00169.24 EGD98492.1 - 0.12 12.6 0.0 0.4 10.9 0.0 1.9 1 1 0 1 1 1 0 PH domain Spore_III_AB PF09548.5 EGD98492.1 - 1.3 8.7 3.4 20 4.8 0.0 2.7 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Arrestin_C PF02752.17 EGD98493.1 - 1.7e-17 63.8 0.0 5.1e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGD98493.1 - 6.2e-15 55.3 0.0 4.7e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EGD98493.1 - 0.13 11.7 0.0 0.41 10.1 0.0 1.8 1 0 0 1 1 1 0 Arrestin_N terminal like DUF3322 PF11795.3 EGD98494.1 - 0.088 12.4 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Hexapep PF00132.19 EGD98495.1 - 2.1e-06 26.9 9.4 0.00026 20.3 2.1 4.2 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGD98495.1 - 1.7e-05 24.3 2.0 0.0016 17.9 0.3 2.7 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EGD98495.1 - 0.017 13.6 0.2 0.023 13.2 0.1 1.1 1 0 0 1 1 1 0 L-fucokinase An_peroxidase PF03098.10 EGD98496.1 - 5.5e-95 318.7 0.0 1.4e-92 310.8 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EGD98496.1 - 2.2e-08 33.0 0.0 1e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.4 EGD98497.1 - 6.6e-105 350.4 0.1 8.6e-105 350.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) GPI-anchored PF10342.4 EGD98498.1 - 0.099 13.1 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MARVEL PF01284.18 EGD98499.1 - 7.8e-05 22.5 12.5 0.00015 21.6 8.7 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF4231 PF14015.1 EGD98499.1 - 0.098 12.6 6.2 0.083 12.8 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PGA2 PF07543.7 EGD98500.1 - 3.6e-34 117.5 1.5 4.1e-34 117.3 1.0 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 CCD PF07860.6 EGD98500.1 - 0.0032 16.9 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 WisP family C-Terminal Region Remorin_C PF03763.8 EGD98500.1 - 1.1 8.7 8.4 0.14 11.6 0.7 2.0 1 1 0 2 2 2 0 Remorin, C-terminal region CENP-S PF15630.1 EGD98501.1 - 9.5e-31 105.8 0.0 1.2e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EGD98501.1 - 3.7e-06 26.4 0.0 4.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EGD98501.1 - 0.0061 16.2 0.0 0.012 15.2 0.0 1.5 1 1 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 EGD98501.1 - 0.0085 15.8 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit MMS1_N PF10433.4 EGD98502.1 - 3.7e-77 259.5 0.1 4e-76 256.1 0.0 2.2 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EGD98502.1 - 1.4e-61 208.3 0.1 9.8e-61 205.5 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region PQQ_2 PF13360.1 EGD98502.1 - 0.026 13.9 0.6 2.5 7.4 0.0 3.3 3 1 0 3 3 3 0 PQQ-like domain PQQ_3 PF13570.1 EGD98502.1 - 0.66 10.3 4.1 10 6.5 0.2 4.5 5 0 0 5 5 5 0 PQQ-like domain NAD_binding_2 PF03446.10 EGD98503.1 - 1.8e-36 125.4 0.0 2.7e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGD98503.1 - 1.5e-29 102.5 0.0 2.4e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EGD98503.1 - 3.6e-07 30.5 0.0 1.3e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EGD98503.1 - 9.8e-05 21.5 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EGD98503.1 - 0.00035 21.0 0.0 0.00074 20.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ABC_membrane PF00664.18 EGD98504.1 - 1.3e-80 270.7 38.2 2e-43 148.8 11.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD98504.1 - 1.9e-63 212.8 0.0 3.3e-33 114.8 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGD98504.1 - 9.3e-16 57.7 4.4 5.5e-06 25.7 0.5 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD98504.1 - 8.5e-14 52.1 0.6 0.00061 19.8 0.0 4.6 3 2 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EGD98504.1 - 1.7e-09 37.9 0.7 9.9e-05 22.3 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EGD98504.1 - 1.5e-08 33.9 0.0 0.0032 16.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGD98504.1 - 5.6e-08 33.6 0.0 0.0026 18.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EGD98504.1 - 9.2e-08 31.0 0.4 0.0017 16.9 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Rad17 PF03215.10 EGD98504.1 - 4e-07 29.1 0.1 0.0035 16.0 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EGD98504.1 - 7.5e-07 29.3 4.9 0.022 14.8 0.0 4.2 4 1 0 4 4 3 2 AAA domain AAA PF00004.24 EGD98504.1 - 9.3e-07 29.1 0.3 0.14 12.3 0.0 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EGD98504.1 - 3e-06 26.6 1.0 0.002 17.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 EGD98504.1 - 4.1e-06 26.1 0.0 0.025 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 EGD98504.1 - 2.4e-05 24.0 0.1 0.45 10.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EGD98504.1 - 2.8e-05 24.4 0.3 0.044 14.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGD98504.1 - 4.2e-05 23.0 1.3 0.085 12.2 0.1 3.4 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.1 EGD98504.1 - 0.00023 20.8 0.0 0.72 9.6 0.0 4.1 4 0 0 4 4 3 1 Part of AAA domain ATP-synt_ab PF00006.20 EGD98504.1 - 0.00023 20.7 0.2 0.14 11.6 0.0 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 EGD98504.1 - 0.00026 20.7 0.0 1.8 8.2 0.0 3.4 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EGD98504.1 - 0.00055 19.8 1.1 0.53 10.2 0.1 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EGD98504.1 - 0.0011 18.1 0.0 0.16 11.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 EGD98504.1 - 0.002 18.0 0.0 0.7 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGD98504.1 - 0.002 18.0 0.2 0.75 9.7 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.1 EGD98504.1 - 0.0026 17.7 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EGD98504.1 - 0.0037 16.9 0.0 6.9 6.3 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EGD98504.1 - 0.005 17.2 11.2 0.0079 16.5 0.0 3.4 3 0 0 3 3 2 1 AAA domain PRK PF00485.13 EGD98504.1 - 0.0076 15.8 0.0 3 7.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 EGD98504.1 - 0.012 15.8 0.0 4.2 7.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.17 EGD98504.1 - 0.017 14.5 0.0 2.9 7.2 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 EGD98504.1 - 0.04 13.8 0.1 3 7.8 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF3987 PF13148.1 EGD98504.1 - 0.061 11.8 6.3 0.34 9.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) IstB_IS21 PF01695.12 EGD98504.1 - 0.37 10.1 2.6 9.2 5.6 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein Pterin_4a PF01329.14 EGD98507.1 - 1.2e-20 72.9 0.0 1.5e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase WSC PF01822.14 EGD98508.1 - 8e-37 125.0 33.3 3.4e-19 68.5 8.7 2.6 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.18 EGD98508.1 - 3.1e-22 79.1 0.2 5.8e-22 78.3 0.2 1.4 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.13 EGD98508.1 - 0.013 15.4 0.1 0.042 13.8 0.1 1.8 1 0 0 1 1 1 0 Photosystem I psaG / psaK Flg_new PF09479.5 EGD98508.1 - 0.046 13.7 0.9 0.59 10.2 0.0 3.1 3 0 0 3 3 3 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Glyco_trans_2_3 PF13632.1 EGD98509.1 - 6.3e-50 169.5 0.9 6.3e-50 169.5 0.6 2.8 2 1 1 3 3 3 1 Glycosyl transferase family group 2 DUF3471 PF11954.3 EGD98509.1 - 0.0085 15.9 0.0 0.025 14.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) Glycos_transf_2 PF00535.21 EGD98509.1 - 0.088 12.4 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_hydro_16 PF00722.16 EGD98510.1 - 1.2e-21 76.7 0.2 2.2e-20 72.7 0.0 2.5 1 1 2 3 3 3 1 Glycosyl hydrolases family 16 WSC PF01822.14 EGD98511.1 - 2.5e-48 161.9 45.0 5e-19 68.0 7.4 3.3 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.6 EGD98511.1 - 9e-28 96.9 0.0 1e-26 93.5 0.0 2.5 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EGD98511.1 - 8.2e-22 77.1 0.0 1.5e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.10 EGD98511.1 - 0.036 13.8 0.0 0.37 10.6 0.0 2.8 2 0 0 2 2 2 0 Kelch motif MFS_1 PF07690.11 EGD98512.1 - 4.2e-14 52.0 70.5 1.1e-08 34.2 17.0 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EGD98512.1 - 7e-05 21.2 27.4 0.0001 20.6 19.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-H2C2_2 PF13465.1 EGD98513.1 - 2.1e-08 34.0 12.5 2.5e-06 27.4 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGD98513.1 - 1.9e-07 30.9 13.9 4.8e-05 23.3 4.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD98513.1 - 0.00025 21.2 16.8 0.0047 17.1 4.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EGD98513.1 - 0.00028 20.9 4.6 0.016 15.3 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EGD98513.1 - 0.0011 19.0 8.6 0.0019 18.2 5.6 1.8 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.2 EGD98513.1 - 0.04 13.7 1.5 0.077 12.8 1.1 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-met PF12874.2 EGD98513.1 - 0.047 13.9 5.3 0.49 10.6 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EGD98513.1 - 0.067 12.9 1.2 0.067 12.9 0.8 2.8 3 0 0 3 3 3 0 BED zinc finger zf-C2HC_2 PF13913.1 EGD98513.1 - 0.6 9.8 8.5 2.6 7.8 0.8 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 EGD98513.1 - 1.9 8.6 5.2 6.5 6.9 0.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) APG5 PF04106.7 EGD98514.1 - 9.5e-67 224.2 0.0 1.1e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg5 Zip PF02535.17 EGD98515.1 - 0.37 9.7 10.4 0.44 9.4 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 EGD98515.1 - 0.48 9.2 10.6 0.61 8.8 7.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SelP_N PF04592.9 EGD98515.1 - 3 7.1 14.8 4.2 6.6 10.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1466 PF07326.6 EGD98515.1 - 5.6 6.1 13.4 8.6 5.5 9.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1466) MFS_1 PF07690.11 EGD98516.1 - 5.4e-18 64.8 55.9 3e-17 62.3 36.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGD98516.1 - 0.017 14.9 0.6 0.017 14.9 0.4 2.7 2 0 0 2 2 2 0 MFS_1 like family Arrestin_N PF00339.24 EGD98519.1 - 3.8e-16 59.2 0.0 4.6e-14 52.4 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain SHR3_chaperone PF08229.6 EGD98521.1 - 1.2e-78 262.5 0.0 1.5e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 MLANA PF14991.1 EGD98521.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A DUF1212 PF06738.7 EGD98524.1 - 0.4 10.1 1.7 0.34 10.3 0.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) DUF4199 PF13858.1 EGD98525.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Peptidase_M28 PF04389.12 EGD98526.1 - 4e-29 101.6 0.1 6.1e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGD98526.1 - 0.027 14.0 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 FG-GAP_2 PF14312.1 EGD98526.1 - 0.083 12.9 0.9 2.8 7.9 0.6 2.8 1 1 0 1 1 1 0 FG-GAP repeat DUF1257 PF06868.6 EGD98526.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) Glyco_hydro_81 PF03639.8 EGD98527.1 - 1.6e-179 598.3 2.3 1.3e-171 572.0 0.4 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 81 Utp14 PF04615.8 EGD98529.1 - 3.6e-210 699.9 59.7 3.6e-210 699.9 41.4 2.7 1 1 2 3 3 3 1 Utp14 protein MRP-L27 PF09809.4 EGD98530.1 - 1.4e-12 47.2 0.2 2e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HECT PF00632.20 EGD98531.1 - 7.7e-84 281.5 0.0 1.4e-83 280.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EGD98531.1 - 0.033 13.8 0.2 0.033 13.8 0.1 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif RRM_1 PF00076.17 EGD98532.1 - 4.8e-81 266.3 5.5 1.5e-22 78.9 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD98532.1 - 1.5e-55 185.0 0.3 2.1e-15 56.4 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD98532.1 - 8.1e-42 140.8 0.3 6.5e-11 41.9 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EGD98532.1 - 2.1e-28 97.7 1.1 9.4e-28 95.6 0.2 2.5 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EGD98532.1 - 1.9e-05 24.3 0.1 7.7 6.3 0.0 5.0 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EGD98532.1 - 2.8e-05 23.7 1.4 2.7 7.7 0.0 3.8 3 0 0 3 3 3 3 Limkain b1 CbiG_mid PF11761.3 EGD98532.1 - 0.00019 21.5 0.0 2.8 8.2 0.0 3.7 3 0 0 3 3 3 2 Cobalamin biosynthesis central region OB_RNB PF08206.6 EGD98532.1 - 0.059 12.8 2.3 9.5 5.8 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Fe-ADH PF00465.14 EGD98533.1 - 7e-67 225.6 0.7 8.2e-67 225.4 0.5 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGD98533.1 - 7.4e-20 71.3 0.0 1.2e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EGD98533.1 - 0.0011 17.9 0.1 0.42 9.4 0.0 2.3 2 1 0 2 2 2 2 3-dehydroquinate synthase KfrA_N PF11740.3 EGD98533.1 - 0.011 16.1 0.1 6.7 7.1 0.0 2.7 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term Peripla_BP_6 PF13458.1 EGD98533.1 - 0.017 14.5 0.1 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein DAO PF01266.19 EGD98534.1 - 8.7e-36 123.5 0.4 2.7e-33 115.3 0.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD98534.1 - 1.5e-05 24.9 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGD98534.1 - 0.00013 22.0 0.1 0.00018 21.6 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD98534.1 - 0.0012 17.9 1.6 0.002 17.2 1.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGD98534.1 - 0.002 17.2 0.2 0.014 14.5 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EGD98534.1 - 0.0039 16.9 0.0 0.0091 15.7 0.0 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EGD98534.1 - 0.0095 14.8 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGD98534.1 - 0.01 15.7 0.1 0.013 15.4 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD98534.1 - 0.013 14.6 0.2 0.04 13.0 0.0 1.7 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 EGD98534.1 - 0.035 13.7 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EGD98534.1 - 0.037 14.4 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EGD98534.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase Vps52 PF04129.7 EGD98535.1 - 1.1e-123 413.4 2.6 1.3e-123 413.1 1.8 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EGD98535.1 - 1e-07 30.5 5.1 1.6e-07 29.9 3.5 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Nup54 PF13874.1 EGD98535.1 - 0.067 12.8 0.1 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 COG2 PF06148.6 EGD98535.1 - 0.077 12.8 1.1 0.19 11.5 0.1 2.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RIH_assoc PF08454.6 EGD98535.1 - 0.15 11.6 2.0 0.26 10.9 0.5 2.1 2 0 0 2 2 2 0 RyR and IP3R Homology associated eIF-5a PF01287.15 EGD98536.1 - 7e-25 86.7 0.6 1e-24 86.2 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EGD98536.1 - 3e-05 23.5 0.9 6.6e-05 22.4 0.6 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EGD98536.1 - 0.0022 17.7 0.4 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain RRN7 PF11781.3 EGD98537.1 - 2.2e-06 27.0 5.2 4.2e-06 26.1 3.6 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Ribosomal_L40e PF01020.12 EGD98538.1 - 2.3e-20 71.9 7.9 4.5e-20 70.9 5.5 1.5 1 1 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 EGD98538.1 - 1e-18 66.4 0.0 1.4e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGD98538.1 - 2.2e-07 30.4 0.0 3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Yip1 PF04893.12 EGD98539.1 - 1.5e-15 57.1 16.8 3e-15 56.1 11.7 1.5 1 1 0 1 1 1 1 Yip1 domain RabGAP-TBC PF00566.13 EGD98540.1 - 1.4e-26 93.3 0.2 4.5e-26 91.6 0.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain IGF2_C PF08365.6 EGD98541.1 - 5.8 6.7 6.9 1.7 8.4 2.5 1.9 2 1 0 2 2 2 0 Insulin-like growth factor II E-peptide MMS1_N PF10433.4 EGD98542.1 - 9.1e-131 436.4 0.0 2.4e-130 435.0 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EGD98542.1 - 1.8e-05 24.0 0.0 0.00015 21.0 0.0 2.0 1 1 0 1 1 1 1 CPSF A subunit region Lgl_C PF08596.5 EGD98542.1 - 0.12 10.8 0.0 4.9 5.5 0.0 2.7 3 0 0 3 3 3 0 Lethal giant larvae(Lgl) like, C-terminal GTP_EFTU PF00009.22 EGD98543.1 - 1e-32 113.1 0.0 6.6e-32 110.4 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGD98543.1 - 6.2e-20 71.1 0.1 1.7e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EGD98543.1 - 1.2e-11 44.4 0.7 1.2e-09 38.0 0.0 3.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGD98543.1 - 2.6e-06 27.3 0.0 1.1e-05 25.3 0.0 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD98543.1 - 0.0013 19.1 0.0 0.0072 16.8 0.0 2.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EGD98543.1 - 0.0018 17.8 0.0 0.0084 15.7 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EGD98543.1 - 0.0051 16.3 0.0 0.015 14.8 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Rhodanese PF00581.15 EGD98544.1 - 5.9e-12 45.9 0.0 1.2e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain p450 PF00067.17 EGD98545.1 - 2.6e-53 181.1 0.0 3.7e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase_2 PF12681.2 EGD98546.1 - 2.6e-08 34.4 0.0 3.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGD98546.1 - 0.0039 17.1 0.0 0.04 13.8 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PPR_3 PF13812.1 EGD98548.1 - 8.4e-20 69.3 4.3 0.00013 21.9 0.0 9.5 9 0 0 9 9 9 5 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGD98548.1 - 9.5e-20 70.3 4.9 3.9e-09 36.3 0.0 6.3 4 2 2 6 6 6 5 PPR repeat family PPR PF01535.15 EGD98548.1 - 5.3e-19 66.8 2.2 2.8e-05 23.7 0.0 8.5 8 0 0 8 8 8 5 PPR repeat PPR_1 PF12854.2 EGD98548.1 - 2.1e-07 30.2 0.0 0.16 11.4 0.0 5.5 6 0 0 6 6 6 2 PPR repeat MCM PF00493.18 EGD98549.1 - 5.4e-130 433.0 0.3 7.8e-130 432.4 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGD98549.1 - 3.3e-17 63.0 0.0 1.2e-16 61.2 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGD98549.1 - 9.8e-07 28.1 0.0 1.2e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGD98549.1 - 0.0038 16.8 0.0 0.0088 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGD98549.1 - 0.08 12.4 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Spo7 PF03907.8 EGD98550.1 - 2.9e-65 219.7 0.0 4.7e-65 219.1 0.0 1.3 1 1 0 1 1 1 1 Spo7-like protein YL1 PF05764.8 EGD98550.1 - 0.078 12.5 5.3 0.17 11.4 3.7 1.5 1 1 0 1 1 1 0 YL1 nuclear protein DUF1180 PF06679.7 EGD98550.1 - 5.2 6.9 7.0 0.71 9.7 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Abhydrolase_6 PF12697.2 EGD98551.1 - 2.6e-28 99.4 0.1 8.4e-28 97.7 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD98551.1 - 4.8e-16 59.0 0.0 5.9e-12 45.6 0.0 2.9 2 2 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD98551.1 - 2.4e-14 53.2 0.0 2.1e-11 43.7 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EGD98551.1 - 6.2e-05 22.5 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EGD98551.1 - 0.00016 22.0 0.2 0.0055 16.9 0.1 2.9 2 1 0 2 2 2 1 Thioesterase domain Chlorophyllase2 PF12740.2 EGD98551.1 - 0.00059 18.8 0.0 0.00095 18.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF915 PF06028.6 EGD98551.1 - 0.0011 18.1 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 EGD98551.1 - 0.0025 17.2 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 EGD98551.1 - 0.0031 17.1 0.0 0.0096 15.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGD98551.1 - 0.004 16.9 0.0 0.015 15.1 0.0 2.0 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 EGD98551.1 - 0.0078 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase PF07224.6 EGD98551.1 - 0.0081 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.11 EGD98551.1 - 0.0091 15.4 0.0 3.5 7.0 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 EGD98551.1 - 0.026 14.1 0.0 0.3 10.6 0.0 2.5 3 0 0 3 3 3 0 Serine hydrolase Peptidase_S9 PF00326.16 EGD98551.1 - 0.043 13.0 0.0 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family TatD_DNase PF01026.16 EGD98552.1 - 1.5e-37 129.2 0.0 2.5e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase TPP_enzyme_N PF02776.13 EGD98553.1 - 1.5e-38 131.9 0.0 8.3e-38 129.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGD98553.1 - 5.3e-21 74.7 0.1 1e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGD98553.1 - 3.3e-20 72.2 0.0 2e-19 69.6 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain NTP_transf_3 PF12804.2 EGD98553.1 - 0.077 13.0 0.9 2.3 8.2 0.3 3.2 2 1 0 2 2 2 0 MobA-like NTP transferase domain DEK_C PF08766.6 EGD98554.1 - 2.2e-17 62.5 0.7 2.9e-17 62.1 0.5 1.2 1 0 0 1 1 1 1 DEK C terminal domain Chitin_synth_2 PF03142.10 EGD98555.1 - 4.1e-229 761.3 0.0 5.7e-229 760.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EGD98555.1 - 6.3e-69 232.7 0.0 4.3e-68 230.0 0.0 2.2 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EGD98555.1 - 2.5e-22 78.4 0.0 3.1e-12 46.1 0.0 2.5 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EGD98555.1 - 2.6e-15 56.6 5.7 2.6e-15 56.6 4.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGD98555.1 - 7.5e-15 55.3 0.0 7e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGD98555.1 - 1.6e-06 27.5 0.0 4.8e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGD98555.1 - 0.0007 19.3 0.0 0.076 12.6 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 EGD98557.1 - 1.9e-254 844.9 0.4 2.8e-254 844.4 0.3 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EGD98557.1 - 9.6e-180 599.0 0.0 1.3e-179 598.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EGD98557.1 - 4.4e-18 64.8 0.0 9.9e-13 47.7 0.0 3.3 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EGD98557.1 - 9.1e-17 60.5 2.0 2.8e-16 59.0 1.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EGD98557.1 - 2e-15 57.0 5.5 2e-15 57.0 3.8 1.8 2 0 0 2 2 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGD98557.1 - 1.5e-14 54.3 0.1 2e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGD98557.1 - 6.9e-05 22.6 0.0 0.0047 16.6 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGD98557.1 - 0.00074 18.8 0.3 0.0053 16.0 0.2 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 AAA_16 PF13191.1 EGD98557.1 - 0.0039 17.2 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EGD98557.1 - 0.021 14.0 0.0 0.41 9.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGD98557.1 - 0.11 12.5 0.1 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain KH_1 PF00013.24 EGD98558.1 - 7.9e-25 86.2 0.3 1.6e-06 27.6 0.1 6.6 7 0 0 7 7 7 5 KH domain KH_3 PF13014.1 EGD98558.1 - 3.1e-21 74.5 3.7 0.00068 19.2 0.0 6.7 7 0 0 7 7 7 5 KH domain PAT1 PF09770.4 EGD98558.1 - 0.087 11.0 30.3 0.12 10.5 21.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EGD98558.1 - 0.32 10.8 10.5 0.52 10.1 7.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HAD_2 PF13419.1 EGD98559.1 - 3.2e-28 99.1 0.8 3.9e-28 98.8 0.6 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD98559.1 - 3.1e-06 26.7 0.0 5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like TATR PF03430.8 EGD98560.1 - 0.21 10.1 1.5 0.33 9.5 1.1 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Dynactin PF12455.3 EGD98561.1 - 3.8e-95 317.9 1.3 3.8e-95 317.9 0.9 3.7 3 1 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 EGD98561.1 - 3e-19 68.4 0.1 5.4e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Beta_elim_lyase PF01212.16 EGD98562.1 - 1.9e-82 276.6 0.1 2.3e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EGD98562.1 - 4.2e-08 32.5 0.0 7.6e-08 31.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGD98562.1 - 4.2e-06 25.7 0.1 9.7e-06 24.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGD98562.1 - 0.00013 21.1 0.0 0.041 12.9 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EGD98562.1 - 0.002 16.5 0.1 0.0047 15.2 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 EGD98562.1 - 0.052 12.0 0.0 0.079 11.4 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Solute_trans_a PF03619.11 EGD98564.1 - 5.1e-98 327.7 7.9 6.7e-98 327.3 5.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha GTP_EFTU PF00009.22 EGD98566.1 - 2.9e-62 209.4 0.1 4e-62 209.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGD98566.1 - 6.3e-35 119.3 0.0 2.1e-34 117.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EGD98566.1 - 3.4e-21 74.9 0.0 1e-20 73.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EGD98566.1 - 3.3e-12 46.0 0.0 9.6e-12 44.5 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EGD98566.1 - 1e-05 25.4 0.0 3e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EGD98566.1 - 0.0052 16.8 0.0 0.068 13.2 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RRM_6 PF14259.1 EGD98567.1 - 2.6e-10 40.1 0.0 2e-09 37.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD98567.1 - 1e-08 34.6 0.1 9.1e-06 25.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EGD98567.1 - 2.1e-07 30.9 0.1 4.1e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 EGD98567.1 - 5.6e-07 29.3 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD98567.1 - 7.3e-05 22.4 0.0 0.00072 19.2 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EGD98567.1 - 0.00017 21.1 1.1 0.0003 20.3 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 EGD98567.1 - 2.3 8.1 9.9 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif adh_short PF00106.20 EGD98568.1 - 3.4e-09 36.8 0.0 4.7e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD98568.1 - 0.0074 16.0 0.0 0.0083 15.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.11 EGD98569.1 - 2.2e-41 141.7 16.6 4.7e-41 140.6 11.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD98569.1 - 7.5e-11 41.2 13.2 1.3e-10 40.4 9.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EGD98569.1 - 3.3e-07 29.0 9.3 3.3e-07 29.0 6.4 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein NfeD PF01957.13 EGD98569.1 - 0.004 17.2 10.1 0.1 12.7 0.1 3.8 4 0 0 4 4 4 2 NfeD-like C-terminal, partner-binding DUF4131 PF13567.1 EGD98569.1 - 6 6.2 14.9 5.9 6.2 1.8 3.3 2 2 0 2 2 2 0 Domain of unknown function (DUF4131) DUF663 PF04950.7 EGD98571.1 - 2.5e-92 309.0 0.0 2.5e-92 309.0 0.0 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EGD98571.1 - 1.4e-26 91.8 0.0 2.9e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EGD98571.1 - 2.1e-07 30.5 0.0 2e-05 24.0 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGD98571.1 - 2.8e-05 24.2 0.0 7.2e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD98571.1 - 0.00011 22.2 0.1 0.00042 20.3 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.24 EGD98571.1 - 0.00014 22.0 0.0 0.00035 20.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EGD98571.1 - 0.00057 19.5 0.3 0.0014 18.3 0.2 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EGD98571.1 - 0.00073 19.4 0.0 0.002 18.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EGD98571.1 - 0.0011 19.8 0.0 0.0011 19.8 0.0 4.3 4 1 1 5 5 2 1 AAA domain Miro PF08477.8 EGD98571.1 - 0.0014 19.0 0.0 0.0048 17.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EGD98571.1 - 0.002 17.6 0.0 0.0084 15.5 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 EGD98571.1 - 0.0027 17.4 0.3 0.0053 16.4 0.2 1.4 1 0 0 1 1 1 1 NTPase AAA_33 PF13671.1 EGD98571.1 - 0.0042 16.9 0.1 0.018 14.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EGD98571.1 - 0.0048 16.5 0.2 0.011 15.3 0.2 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EGD98571.1 - 0.0057 15.5 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 EGD98571.1 - 0.007 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase cobW PF02492.14 EGD98571.1 - 0.0074 15.7 0.1 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EGD98571.1 - 0.0077 15.8 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 EGD98571.1 - 0.0087 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGD98571.1 - 0.012 15.0 0.0 0.051 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGD98571.1 - 0.014 15.6 0.0 0.014 15.6 0.0 3.1 3 0 0 3 3 1 0 AAA domain ABC_tran PF00005.22 EGD98571.1 - 0.016 15.4 1.7 0.027 14.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 EGD98571.1 - 0.042 13.5 0.8 0.081 12.6 0.1 1.8 2 0 0 2 2 1 0 Part of AAA domain AAA_5 PF07728.9 EGD98571.1 - 0.048 13.4 0.2 0.15 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EGD98571.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_11 PF13086.1 EGD98571.1 - 0.1 12.1 3.3 0.71 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EGD98571.1 - 0.14 11.7 0.1 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.12 EGD98571.1 - 0.14 11.6 0.1 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Aminotran_1_2 PF00155.16 EGD98572.1 - 8.1e-39 133.5 0.0 1.1e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD98572.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DUF1989 PF09347.5 EGD98575.1 - 7.3e-45 152.3 0.1 1e-44 151.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Abhydrolase_6 PF12697.2 EGD98576.1 - 1.9e-23 83.5 0.0 2.5e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD98576.1 - 6.7e-09 35.6 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD98576.1 - 1.1e-07 31.6 0.0 3.2e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGD98576.1 - 0.008 15.6 0.0 4.3 6.7 0.0 3.0 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 EGD98576.1 - 0.0095 15.7 0.0 0.043 13.6 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase NADH_Oxid_Nqo15 PF11497.3 EGD98576.1 - 0.034 13.8 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 DUF3425 PF11905.3 EGD98577.1 - 1.4e-22 80.0 0.0 2.4e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EGD98577.1 - 0.0018 18.2 8.9 0.0031 17.4 6.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGD98577.1 - 0.11 12.3 7.0 0.22 11.3 4.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Inhibitor_I9 PF05922.11 EGD98578.1 - 0.03 14.8 0.0 0.04 14.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 BCDHK_Adom3 PF10436.4 EGD98579.1 - 1.3e-43 148.3 0.1 1.8e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGD98579.1 - 1.1e-14 54.0 0.0 7e-14 51.4 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGD98579.1 - 0.0056 16.4 0.0 0.022 14.5 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain Lactamase_B_2 PF12706.2 EGD98580.1 - 4.9e-20 71.9 1.2 6.6e-20 71.4 0.8 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGD98580.1 - 3.7e-10 39.7 2.5 2.2e-09 37.2 1.7 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGD98580.1 - 0.35 10.5 9.4 6.2 6.4 5.5 2.8 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily ketoacyl-synt PF00109.21 EGD98581.1 - 1.3e-46 159.1 6.8 1.5e-24 86.9 1.0 3.0 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGD98581.1 - 7.6e-34 116.1 0.4 1.8e-33 114.9 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EGD98581.1 - 2.6e-06 26.6 0.1 5.9e-05 22.1 0.1 2.6 3 0 0 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGD98581.1 - 0.026 13.9 0.4 0.026 13.9 0.3 2.9 2 2 0 2 2 2 0 Thiolase, C-terminal domain Arginase PF00491.16 EGD98582.1 - 2.5e-85 286.1 0.4 3.1e-85 285.8 0.3 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EGD98582.1 - 0.00099 19.3 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 UPF0489 domain Ras PF00071.17 EGD98583.1 - 1.3e-52 177.4 0.0 1.5e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD98583.1 - 1.5e-16 60.9 0.0 2.4e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD98583.1 - 4.3e-06 26.0 0.0 6.1e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF1349 PF07081.6 EGD98584.1 - 1.6e-22 79.7 0.0 1e-19 70.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1349) MFS_1 PF07690.11 EGD98585.1 - 3.5e-21 75.3 39.5 9.1e-20 70.6 27.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1435 PF07256.7 EGD98585.1 - 0.0044 16.9 3.2 0.14 12.1 0.3 3.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1435) DUF2530 PF10745.4 EGD98585.1 - 0.015 15.2 0.4 0.085 12.8 0.1 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2530) COX6A PF02046.10 EGD98585.1 - 0.16 11.8 0.2 1.3 8.9 0.0 2.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIa p450 PF00067.17 EGD98586.1 - 1.3e-47 162.4 0.0 1.7e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Vint PF14623.1 EGD98587.1 - 7.3e-55 184.8 0.0 2.3e-54 183.2 0.0 1.9 2 0 0 2 2 2 1 Hint-domain Vwaint PF14624.1 EGD98587.1 - 6.6e-31 106.2 0.0 1.3e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 EGD98587.1 - 7e-19 68.5 0.0 1.3e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGD98587.1 - 6.5e-17 61.8 0.0 1.1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EGD98587.1 - 6.3e-14 51.9 0.0 2.9e-10 40.0 0.0 3.3 3 0 0 3 3 3 2 von Willebrand factor type A domain ABC_membrane PF00664.18 EGD98588.1 - 2.1e-92 309.4 27.4 1.7e-47 162.1 6.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD98588.1 - 2.8e-67 225.2 0.0 5.2e-33 114.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGD98588.1 - 1.5e-13 50.5 0.3 0.00015 21.0 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD98588.1 - 4.5e-12 46.5 0.2 0.067 13.1 0.0 4.3 2 2 2 4 4 4 3 AAA domain AAA_16 PF13191.1 EGD98588.1 - 3.6e-08 33.6 2.3 0.00016 21.7 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EGD98588.1 - 5.1e-08 33.7 0.0 0.0062 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGD98588.1 - 1.9e-07 30.5 3.1 0.00057 19.3 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EGD98588.1 - 7.5e-07 28.0 0.2 0.039 12.5 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EGD98588.1 - 8.3e-07 28.3 0.0 0.037 13.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGD98588.1 - 7.1e-06 26.1 0.5 0.15 12.2 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EGD98588.1 - 0.00014 21.5 0.8 1.2 8.7 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EGD98588.1 - 0.00016 22.0 0.0 0.58 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGD98588.1 - 0.0003 20.5 0.4 0.12 12.1 0.0 3.2 4 0 0 4 4 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGD98588.1 - 0.00043 20.1 0.1 1 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EGD98588.1 - 0.00084 19.5 0.5 1.3 9.2 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGD98588.1 - 0.00092 18.6 0.4 1.3 8.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGD98588.1 - 0.001 18.7 0.2 2.3 8.0 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain SRP54 PF00448.17 EGD98588.1 - 0.0018 17.7 0.1 1.9 7.8 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 EGD98588.1 - 0.0019 18.0 3.3 0.35 10.8 0.5 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EGD98588.1 - 0.002 18.0 0.0 5.2 6.9 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.1 EGD98588.1 - 0.0032 17.8 0.1 0.67 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGD98588.1 - 0.0038 16.3 0.2 1 8.4 0.0 2.7 3 0 0 3 3 2 1 Zeta toxin MobB PF03205.9 EGD98588.1 - 0.0085 15.8 0.1 6 6.5 0.0 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EGD98588.1 - 0.0086 16.0 0.6 3 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EGD98588.1 - 0.011 15.1 0.3 9.9 5.4 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain G-alpha PF00503.15 EGD98588.1 - 0.023 13.4 0.0 1.2 7.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Rad17 PF03215.10 EGD98588.1 - 0.024 13.3 0.0 0.17 10.5 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 EGD98588.1 - 0.026 13.3 0.3 4.3 6.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.18 EGD98588.1 - 0.058 13.3 0.4 20 5.2 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase KaiC PF06745.8 EGD98588.1 - 0.1 11.7 0.5 7 5.6 0.0 2.4 2 0 0 2 2 2 0 KaiC ATP-synt_ab PF00006.20 EGD98588.1 - 0.1 12.0 1.6 2.7 7.4 0.0 3.6 4 1 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EGD98588.1 - 0.11 12.6 0.4 7.1 6.8 0.0 2.9 3 0 0 3 3 2 0 RNA helicase PRK PF00485.13 EGD98588.1 - 0.14 11.6 0.2 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.1 EGD98588.1 - 0.18 10.8 0.0 4.3 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain X PF00739.14 EGD98589.1 - 0.00039 20.3 0.8 0.072 13.0 0.0 2.2 2 0 0 2 2 2 2 Trans-activation protein X CBFNT PF08143.6 EGD98589.1 - 0.068 14.2 6.3 0.068 14.2 4.4 2.0 2 0 0 2 2 2 0 CBFNT (NUC161) domain CAP59_mtransfer PF11735.3 EGD98590.1 - 6.9e-74 248.1 0.0 9.2e-74 247.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 3-alpha PF03475.9 EGD98590.1 - 0.18 11.5 2.5 0.5 10.1 0.5 2.4 2 0 0 2 2 2 0 3-alpha domain Pentapeptide_4 PF13599.1 EGD98591.1 - 0.17 11.7 0.9 0.37 10.6 0.1 1.8 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Mitofilin PF09731.4 EGD98591.1 - 1.1 7.8 10.6 1.6 7.2 7.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF605 PF04652.11 EGD98595.1 - 0.8 9.0 7.3 0.84 8.9 5.1 1.2 1 0 0 1 1 1 0 Vta1 like GST_N PF02798.15 EGD98596.1 - 2.2e-13 50.1 0.0 4.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGD98596.1 - 7.6e-13 48.5 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD98596.1 - 2.9e-11 43.1 0.0 7e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD98596.1 - 9.9e-11 41.4 0.0 2.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD98596.1 - 8.9e-09 35.7 0.0 1.3e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGD98596.1 - 3.2e-06 26.9 0.0 7.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain APH PF01636.18 EGD98597.1 - 6e-06 26.1 0.0 0.00041 20.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGD98597.1 - 0.0065 15.5 0.0 0.0096 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGD98597.1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family HSDR_N PF04313.9 EGD98598.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.5 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF1762 PF08574.5 EGD98599.1 - 2.3e-14 53.5 7.3 2.3e-14 53.5 5.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) RRM_1 PF00076.17 EGD98600.1 - 2.8e-40 135.8 0.0 7.8e-12 44.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD98600.1 - 1.6e-38 130.4 0.0 1.2e-09 37.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD98600.1 - 8e-19 67.2 0.0 0.00024 20.9 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EGD98600.1 - 1.4e-11 43.8 6.3 1.4e-11 43.8 4.4 2.6 2 0 0 2 2 2 1 Putative RRM domain RRM_3 PF08777.6 EGD98600.1 - 2.5e-05 24.0 0.0 0.095 12.5 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 EGD98600.1 - 0.032 14.2 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain HD PF01966.17 EGD98601.1 - 0.0004 20.3 0.0 0.00082 19.3 0.0 1.6 1 1 0 1 1 1 1 HD domain DIOX_N PF14226.1 EGD98602.1 - 2.4e-19 69.9 0.0 3.4e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGD98602.1 - 3e-18 65.9 0.0 5.1e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF723 PF05265.8 EGD98602.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF723) Pkinase PF00069.20 EGD98603.1 - 2e-27 96.0 0.0 2.6e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98603.1 - 6.1e-25 87.7 0.0 9.3e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD98603.1 - 0.00014 21.0 0.0 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD98603.1 - 0.0015 17.5 0.0 0.0033 16.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGD98603.1 - 0.0079 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGD98603.1 - 0.014 14.7 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EGD98603.1 - 0.037 13.6 1.0 0.24 10.9 0.6 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase YukC PF10140.4 EGD98603.1 - 0.073 11.6 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC RecR PF02132.10 EGD98604.1 - 0.036 13.5 1.0 0.56 9.6 0.1 2.2 2 0 0 2 2 2 0 RecR protein Dynein_light PF01221.13 EGD98605.1 - 2.7e-35 120.2 6.2 6.9e-35 118.9 4.3 1.5 1 1 0 1 1 1 1 Dynein light chain type 1 DUF2681 PF10883.3 EGD98605.1 - 0.44 10.7 2.1 0.74 10.0 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) RRM_1 PF00076.17 EGD98606.1 - 6.7e-73 240.2 0.2 6.8e-19 67.2 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD98606.1 - 5e-59 196.2 0.1 2.6e-12 46.5 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD98606.1 - 9e-31 105.5 0.0 2.5e-07 30.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGD98606.1 - 2e-08 33.8 0.2 0.38 10.5 0.0 5.4 5 0 0 5 5 5 3 Limkain b1 Nup35_RRM_2 PF14605.1 EGD98606.1 - 5.8e-06 25.9 0.0 0.029 14.1 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.7 EGD98606.1 - 0.063 13.2 0.0 9.5 6.3 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif 2 Rota_NS53 PF00981.12 EGD98606.1 - 0.15 10.6 0.1 0.22 10.1 0.1 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Aldo_ket_red PF00248.16 EGD98607.1 - 1.2e-53 181.8 0.0 1.4e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L25p PF01386.14 EGD98608.1 - 0.098 12.7 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L25p family Pkinase PF00069.20 EGD98609.1 - 3.3e-11 42.8 0.0 3.9e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98609.1 - 0.03 13.3 0.0 0.046 12.7 0.0 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase NIF PF03031.13 EGD98610.1 - 8.5e-52 175.0 0.6 1.3e-51 174.3 0.4 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DNase_NucA_NucB PF14040.1 EGD98610.1 - 0.059 13.5 4.8 0.12 12.5 0.1 2.6 2 0 0 2 2 2 0 Deoxyribonuclease NucA/NucB LRR_4 PF12799.2 EGD98611.1 - 1.7e-37 126.4 43.0 4.7e-11 42.0 1.6 7.5 3 1 4 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD98611.1 - 7.7e-21 73.6 51.9 7.7e-07 28.7 4.7 5.1 1 1 5 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 EGD98611.1 - 3.8e-13 47.4 36.9 0.15 12.1 0.9 10.8 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_7 PF13504.1 EGD98611.1 - 2.5e-12 44.8 21.2 2.3 8.7 0.9 10.0 9 1 0 9 9 9 4 Leucine rich repeat LRR_6 PF13516.1 EGD98611.1 - 6.3e-12 44.2 27.8 0.35 11.0 0.2 10.0 5 3 5 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.1 EGD98611.1 - 8.1e-11 41.7 14.8 0.00011 21.8 3.0 3.5 1 1 3 4 4 4 4 Leucine-rich repeat DUF4340 PF14238.1 EGD98611.1 - 0.032 13.9 0.5 0.21 11.2 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4340) WHIM3 PF15614.1 EGD98611.1 - 0.3 10.9 3.1 6.9 6.5 1.1 2.8 2 1 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 ABC_membrane_2 PF06472.10 EGD98612.1 - 7.5e-91 304.1 0.0 1.6e-90 303.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGD98612.1 - 4.5e-18 65.8 0.0 8e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EGD98612.1 - 0.00066 19.1 0.0 0.074 12.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EGD98612.1 - 0.0023 17.9 0.0 0.0078 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EGD98612.1 - 0.021 15.1 4.0 0.25 11.6 2.8 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EGD98612.1 - 0.025 14.8 0.5 0.4 10.8 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EGD98612.1 - 0.041 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ALIX_LYPXL_bnd PF13949.1 EGD98612.1 - 0.044 12.7 0.2 0.07 12.0 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AAA_16 PF13191.1 EGD98612.1 - 0.047 13.6 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EGD98612.1 - 0.082 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain SMC_N PF02463.14 EGD98612.1 - 0.092 11.9 0.1 3.1 6.9 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Sigma54_activat PF00158.21 EGD98612.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Clr2 PF10383.4 EGD98613.1 - 8.4e-20 71.1 0.0 1.6e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 2OG-FeII_Oxy PF03171.15 EGD98614.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SAD_SRA PF02182.12 EGD98615.1 - 1.6e-19 69.7 0.0 3e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain FAST_1 PF06743.10 EGD98615.1 - 0.05 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 CLTH PF10607.4 EGD98616.1 - 4e-27 94.6 0.0 7.7e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EGD98616.1 - 1.9e-16 59.5 1.9 6.5e-16 57.7 1.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EGD98616.1 - 1.8e-05 24.1 0.4 2.9e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EGD98616.1 - 0.00047 19.9 0.7 0.00087 19.0 0.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGD98616.1 - 0.00073 19.2 0.5 0.0014 18.2 0.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGD98616.1 - 0.002 17.7 0.6 0.0036 16.9 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD98616.1 - 0.0024 17.8 1.4 0.0046 16.9 0.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD98616.1 - 0.025 14.2 1.2 0.057 13.0 0.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGD98616.1 - 0.48 10.3 3.3 0.35 10.7 0.9 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING PG_binding_1 PF01471.13 EGD98617.1 - 0.0042 17.0 0.0 0.85 9.6 0.0 3.5 4 0 0 4 4 4 2 Putative peptidoglycan binding domain zf-Tim10_DDP PF02953.10 EGD98618.1 - 5.5e-24 83.2 2.6 7.2e-24 82.8 1.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.4 EGD98618.1 - 0.57 9.8 0.1 0.57 9.8 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase tRNA-synt_2 PF00152.15 EGD98619.1 - 2.7e-80 269.6 0.0 3.4e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGD98619.1 - 1.8e-09 37.2 0.0 4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGD98619.1 - 2.4e-05 23.6 0.0 0.0082 15.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EGD98619.1 - 0.044 13.3 0.0 8.6 5.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) BTB PF00651.26 EGD98620.1 - 6.4e-08 32.5 0.0 9.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 EGD98620.1 - 0.0077 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain PCI PF01399.22 EGD98621.1 - 1.1e-09 38.5 0.0 2.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.9 EGD98621.1 - 0.051 12.9 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Ribosomal_L18ae PF01775.12 EGD98622.1 - 4.2e-59 197.8 1.4 5.2e-59 197.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain NAD_binding_1 PF00175.16 EGD98623.1 - 2e-30 105.5 0.0 3e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGD98623.1 - 7.8e-23 80.4 0.0 1.7e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGD98623.1 - 1.6e-08 34.5 0.0 2.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HMG_box PF00505.14 EGD98624.1 - 2.6e-12 46.8 2.6 1e-11 44.9 1.8 2.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGD98624.1 - 1.6e-07 31.6 2.4 1.6e-07 31.6 1.6 2.3 2 0 0 2 2 2 1 HMG-box domain Amidohydro_1 PF01979.15 EGD98625.1 - 2.7e-63 214.6 1.2 1.4e-62 212.3 0.4 2.0 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.15 EGD98625.1 - 2.1e-53 179.5 1.1 4.6e-53 178.4 0.8 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EGD98625.1 - 2.3e-40 136.4 0.2 2.9e-39 132.9 0.0 2.2 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EGD98625.1 - 1.6e-29 101.8 0.0 3.2e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EGD98625.1 - 2.3e-06 27.3 3.8 6.6e-06 25.8 2.7 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGD98625.1 - 9.8e-05 21.7 0.1 0.0021 17.3 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family Lactamase_B_2 PF12706.2 EGD98626.1 - 5e-12 45.7 0.0 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGD98626.1 - 1.1e-06 28.4 0.0 2.4e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.9 EGD98626.1 - 9.3e-06 25.6 0.0 3.8e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Zip PF02535.17 EGD98627.1 - 0.0053 15.8 2.5 0.0063 15.5 1.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter NicO PF03824.11 EGD98627.1 - 0.026 13.8 4.5 0.037 13.3 3.1 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Ax_dynein_light PF10211.4 EGD98627.1 - 0.074 12.8 0.3 0.21 11.3 0.0 1.9 3 0 0 3 3 3 0 Axonemal dynein light chain BAF1_ABF1 PF04684.8 EGD98627.1 - 0.39 9.5 15.6 0.72 8.6 10.8 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NPR2 PF06218.6 EGD98628.1 - 1.7e-134 448.7 0.0 3.2e-134 447.8 0.0 1.4 2 0 0 2 2 2 1 Nitrogen permease regulator 2 Afi1 PF07792.7 EGD98628.1 - 0.27 11.2 1.1 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ada3 PF10198.4 EGD98629.1 - 2.2e-43 147.1 1.1 2.5e-43 146.9 0.0 1.7 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 zf-RING_2 PF13639.1 EGD98630.1 - 8.1e-12 44.7 8.7 1.4e-11 43.9 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGD98630.1 - 2.8e-06 27.2 5.4 5.7e-06 26.2 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD98630.1 - 3.5e-06 26.6 3.1 6.4e-06 25.7 2.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD98630.1 - 1.2e-05 24.8 3.7 2.1e-05 24.0 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD98630.1 - 2e-05 24.5 2.3 4e-05 23.6 1.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGD98630.1 - 0.00028 20.4 5.2 0.00046 19.7 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGD98630.1 - 0.0045 16.7 2.0 0.0095 15.7 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGD98630.1 - 0.061 13.0 1.5 0.1 12.3 0.3 2.0 1 1 0 1 1 1 0 RING-type zinc-finger DUF1049 PF06305.6 EGD98630.1 - 0.2 11.1 1.2 0.49 9.9 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) zf-C3HC4_4 PF15227.1 EGD98630.1 - 0.34 10.8 4.4 0.71 9.7 3.0 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 EGD98630.1 - 4.5 6.8 6.5 0.52 9.8 0.9 2.1 2 0 0 2 2 2 0 P-11 zinc finger FRG1 PF06229.7 EGD98631.1 - 1.2e-56 191.2 0.1 1.6e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EGD98631.1 - 0.043 13.9 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Fascin domain Toxin-deaminase PF14424.1 EGD98631.1 - 0.11 12.4 1.0 0.2 11.6 0.7 1.4 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases ADH_zinc_N PF00107.21 EGD98632.1 - 5.5e-16 58.3 0.0 7.9e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD98632.1 - 3.9e-09 36.2 0.9 1.3e-08 34.5 0.5 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGD98632.1 - 0.00038 21.3 0.0 0.00066 20.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EGD98632.1 - 0.0063 16.7 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Gp_dh_N PF00044.19 EGD98632.1 - 0.013 15.4 0.0 0.037 13.9 0.0 1.7 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EGD98632.1 - 0.015 15.9 0.0 0.028 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Saccharop_dh PF03435.13 EGD98632.1 - 0.018 14.0 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase FAD_binding_3 PF01494.14 EGD98632.1 - 0.037 13.0 0.6 0.059 12.4 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 EGD98632.1 - 0.065 13.0 0.5 11 5.8 0.0 2.3 1 1 1 2 2 2 0 ThiF family THDPS_N_2 PF14805.1 EGD98632.1 - 0.096 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal NADH_4Fe-4S PF10589.4 EGD98632.1 - 0.83 8.8 4.4 0.22 10.7 0.7 1.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region HECT PF00632.20 EGD98633.1 - 8e-69 232.2 0.0 1.1e-68 231.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) E2 PF08199.6 EGD98633.1 - 0.2 11.2 0.0 0.2 11.2 0.0 3.4 4 0 0 4 4 4 0 Bacteriophage E2-like protein Ribosomal_L15e PF00827.12 EGD98634.1 - 2.1e-90 301.3 13.6 2.4e-90 301.2 9.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Codanin-1_C PF15296.1 EGD98634.1 - 0.14 12.0 0.2 0.26 11.1 0.1 1.5 1 1 0 1 1 1 0 Codanin-1 C-terminus WD40 PF00400.27 EGD98636.1 - 1.2e-37 126.4 9.0 1.9e-09 37.0 0.3 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat EF-hand_1 PF00036.27 EGD98637.1 - 8e-14 49.8 3.5 1.3e-06 27.2 0.3 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EGD98637.1 - 5e-12 45.7 2.6 2.1e-11 43.8 1.4 2.4 2 0 0 2 2 2 1 EF-hand domain pair ZZ PF00569.12 EGD98637.1 - 1.9e-11 43.2 4.6 3.5e-11 42.4 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.1 EGD98637.1 - 7.3e-10 37.8 4.3 0.00039 20.0 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EGD98637.1 - 5e-08 32.4 5.0 0.0012 18.3 0.2 4.0 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 EGD98637.1 - 5.2e-06 25.5 5.4 0.005 16.1 0.2 3.0 3 0 0 3 3 3 2 EF hand C1_3 PF07649.7 EGD98637.1 - 1.1 9.3 6.5 2 8.5 4.5 1.5 1 0 0 1 1 1 0 C1-like domain MFS_1 PF07690.11 EGD98638.1 - 3.2e-50 170.8 67.4 7.4e-49 166.3 33.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD98638.1 - 2.1e-13 49.6 11.7 2.1e-13 49.6 8.1 3.6 2 1 2 5 5 5 2 Sugar (and other) transporter Peptidase_M24 PF00557.19 EGD98639.1 - 7.4e-45 153.0 0.0 8.9e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EGD98639.1 - 0.0027 17.5 6.3 0.0027 17.5 4.4 2.2 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EGD98639.1 - 1.8 8.2 4.8 4.2 7.0 3.3 1.7 1 0 0 1 1 1 0 HIT zinc finger FAD_binding_3 PF01494.14 EGD98640.1 - 6.1e-15 55.1 0.0 1.5e-13 50.5 0.0 2.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGD98640.1 - 0.00014 20.9 0.0 0.00087 18.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGD98640.1 - 0.00057 19.8 0.0 0.0026 17.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD98640.1 - 0.00072 18.7 1.7 0.0052 15.9 0.4 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD98640.1 - 0.0013 18.7 0.1 0.0073 16.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGD98640.1 - 0.0014 19.0 0.0 0.066 13.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD98640.1 - 0.0025 16.3 0.0 0.0042 15.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EGD98640.1 - 0.0026 16.6 0.0 0.0058 15.5 0.0 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.5 EGD98640.1 - 0.004 16.0 0.0 0.0086 14.9 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase Sugar_tr PF00083.19 EGD98642.1 - 1.1e-77 261.5 23.7 1.3e-77 261.3 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD98642.1 - 7.7e-13 47.8 39.8 6.9e-10 38.1 24.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S8 PF00410.14 EGD98643.1 - 1.9e-23 82.6 0.0 3.6e-23 81.8 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 PIP5K PF01504.13 EGD98646.1 - 2.1e-63 213.7 0.6 4.3e-63 212.7 0.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase ATP-synt_F6 PF05511.6 EGD98646.1 - 0.046 13.6 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Cpn60_TCP1 PF00118.19 EGD98647.1 - 2.5e-29 102.2 0.0 3.7e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EGD98647.1 - 4.3e-15 55.3 4.1 4.3e-15 55.3 2.9 2.1 2 0 0 2 2 2 1 FYVE zinc finger XPC-binding PF09280.6 EGD98647.1 - 0.21 11.0 1.9 0.53 9.7 1.3 1.7 1 0 0 1 1 1 0 XPC-binding domain C1_1 PF00130.17 EGD98647.1 - 4.9 6.9 11.7 0.021 14.5 1.8 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPP1 PF10341.4 EGD98648.1 - 5.6e-15 55.2 0.0 1.2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD DUF1769 PF08588.5 EGD98653.1 - 1.1e-25 89.2 0.2 2.4e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Iso_dh PF00180.15 EGD98654.1 - 2.9e-97 325.7 0.0 7e-97 324.4 0.0 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ICMT PF04140.9 EGD98654.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PK PF00224.16 EGD98656.1 - 1.2e-171 570.0 4.8 1.5e-171 569.7 3.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EGD98656.1 - 4.8e-32 109.9 0.0 1.4e-31 108.4 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EGD98656.1 - 1.8e-05 23.7 0.5 5.4e-05 22.1 0.2 1.7 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EGD98656.1 - 0.0013 17.7 0.1 0.023 13.5 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain SUR7 PF06687.7 EGD98657.1 - 2.5e-30 105.6 0.3 3.1e-30 105.3 0.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family KAR9 PF08580.5 EGD98659.1 - 0.59 8.3 7.1 0.89 7.7 4.9 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ribosomal_S17 PF00366.15 EGD98660.1 - 3.9e-30 103.6 0.9 5.8e-30 103.1 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 EGD98661.1 - 2.1e-289 962.6 40.6 2.9e-289 962.1 28.1 1.2 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EGD98661.1 - 2.1e-109 365.1 0.8 2.1e-109 365.1 0.6 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein Pil1 PF13805.1 EGD98662.1 - 8.4e-154 510.4 0.2 1.1e-153 510.1 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EGD98662.1 - 0.047 13.0 1.8 0.078 12.2 0.6 1.7 1 1 1 2 2 2 0 FAM92 protein XPG_N PF00752.12 EGD98663.1 - 7.4e-35 119.2 0.0 1.8e-34 118.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EGD98663.1 - 3.8e-24 84.5 0.0 9.3e-24 83.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EGD98663.1 - 0.00091 19.4 0.0 0.0032 17.6 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.11 EGD98663.1 - 0.035 14.2 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family WD40 PF00400.27 EGD98664.1 - 1.5e-19 69.0 18.8 7.8e-10 38.2 0.3 9.3 11 0 0 11 11 11 6 WD domain, G-beta repeat Metallophos PF00149.23 EGD98666.1 - 3.3e-42 144.1 0.2 4.4e-42 143.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mito_fiss_reg PF05308.6 EGD98666.1 - 0.21 10.9 3.0 0.32 10.3 2.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator WD40 PF00400.27 EGD98667.1 - 1.3e-30 104.1 11.4 3.3e-07 29.9 0.0 7.9 8 1 1 9 9 9 5 WD domain, G-beta repeat eIF2A PF08662.6 EGD98667.1 - 3.1e-05 23.7 0.1 0.017 14.8 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 EGD98667.1 - 0.00023 20.6 0.5 0.00089 18.7 0.4 2.1 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EGD98667.1 - 0.17 11.5 5.9 6.3 6.5 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Microtub_bind PF13931.1 EGD98668.1 - 0.042 13.9 0.0 0.042 13.9 0.0 2.7 3 0 0 3 3 3 0 Kinesin-associated microtubule-binding F-box-like PF12937.2 EGD98670.1 - 0.0028 17.3 0.3 0.0072 16.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD98670.1 - 0.09 12.4 0.1 0.26 10.9 0.1 1.8 1 0 0 1 1 1 0 F-box domain PRANC PF09372.5 EGD98670.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Grp1_Fun34_YaaH PF01184.14 EGD98671.1 - 1.2e-73 246.8 18.6 1.6e-73 246.5 12.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ANTH PF07651.11 EGD98672.1 - 1.4e-34 119.0 0.4 2.2e-18 65.9 0.0 2.2 1 1 1 2 2 2 2 ANTH domain ENTH PF01417.15 EGD98672.1 - 7.5e-10 38.7 0.0 3.6e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 ENTH domain DUF3024 PF11225.3 EGD98673.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) DUF3275 PF11679.3 EGD98673.1 - 4.3 6.9 6.7 3.7 7.1 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) Memo PF01875.12 EGD98674.1 - 9e-60 201.8 0.0 1.2e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Rad4 PF03835.10 EGD98676.1 - 9.4e-11 41.3 0.4 1.5e-10 40.6 0.3 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain SR-25 PF10500.4 EGD98676.1 - 3.5 7.0 10.1 5.9 6.2 3.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3772 PF12607.3 EGD98676.1 - 5.3 6.7 7.2 1.3 8.7 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) F-box PF00646.28 EGD98677.1 - 0.15 11.7 0.6 0.28 10.8 0.4 1.5 1 0 0 1 1 1 0 F-box domain WD40 PF00400.27 EGD98678.1 - 7e-15 54.2 6.0 0.006 16.4 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EGD98678.1 - 1.6e-05 24.5 0.2 9.6e-05 21.9 0.1 2.3 2 0 0 2 2 2 1 PQQ-like domain Lactonase PF10282.4 EGD98678.1 - 0.042 12.9 0.0 0.12 11.4 0.0 1.7 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Cyclin_C PF02984.14 EGD98682.1 - 5.4e-12 45.6 1.8 1.4e-11 44.3 1.2 1.6 1 1 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 EGD98682.1 - 0.0095 15.4 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain START PF01852.14 EGD98682.1 - 0.037 13.3 0.0 0.078 12.2 0.0 1.5 1 1 0 1 1 1 0 START domain Acyl_transf_3 PF01757.17 EGD98684.1 - 7.5e-05 21.7 11.2 0.00018 20.4 7.6 1.7 1 1 0 1 1 1 1 Acyltransferase family Caps_synth_CapC PF14102.1 EGD98684.1 - 0.077 13.1 0.1 0.077 13.1 0.1 1.8 2 0 0 2 2 2 0 Capsule biosynthesis CapC Pyr_redox_2 PF07992.9 EGD98685.1 - 6.5e-15 55.5 0.0 9.4e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD98685.1 - 0.0027 16.2 0.0 0.016 13.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EGD98685.1 - 0.019 14.0 0.0 0.041 12.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 EGD98685.1 - 0.024 13.5 0.1 1.8 7.4 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGD98685.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGD98685.1 - 0.051 13.3 1.9 2.3 7.9 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 EGD98685.1 - 0.055 12.3 1.3 4.7 5.9 0.1 2.4 1 1 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EGD98685.1 - 0.09 12.8 0.3 4.2 7.3 0.2 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGD98685.1 - 0.11 11.4 0.2 0.39 9.7 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain FKBP_C PF00254.23 EGD98689.1 - 2.9e-33 113.7 0.0 3.5e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyt-b5 PF00173.23 EGD98690.1 - 1.3e-16 60.1 0.0 2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Beta-lactamase PF00144.19 EGD98691.1 - 4.7e-26 91.5 0.1 6.6e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Zip PF02535.17 EGD98692.1 - 3.3e-59 200.4 7.5 3.8e-59 200.2 5.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF872 PF05915.7 EGD98692.1 - 0.15 11.8 0.8 3.5 7.5 0.1 3.0 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Tom37_C PF11801.3 EGD98693.1 - 2e-37 128.6 0.0 3.5e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EGD98693.1 - 5.4e-26 90.6 0.0 4e-25 87.8 0.0 2.4 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein Cupin_8 PF13621.1 EGD98694.1 - 7.4e-22 78.0 0.0 1.7e-21 76.8 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGD98694.1 - 5.6e-05 22.5 0.0 0.00019 20.8 0.0 1.7 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 EGD98694.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.6 EGD98694.1 - 0.013 14.9 0.0 0.031 13.7 0.0 1.7 1 0 0 1 1 1 0 Cupin domain PsbT PF01405.12 EGD98696.1 - 0.18 11.3 2.3 0.37 10.4 1.6 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre T protein bZIP_1 PF00170.16 EGD98697.1 - 0.0068 16.3 7.1 0.012 15.5 4.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGD98697.1 - 0.019 14.7 6.2 0.029 14.1 4.3 1.2 1 0 0 1 1 1 0 Basic region leucine zipper SEEEED PF14797.1 EGD98697.1 - 0.051 13.7 1.2 0.1 12.7 0.8 1.4 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Chitin_bind_3 PF03067.10 EGD98698.1 - 0.14 12.4 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Chitin binding domain Aminotran_4 PF01063.14 EGD98699.1 - 2.4e-29 102.4 0.0 3.8e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 EGD98700.1 - 5.2e-18 65.1 0.0 1.3e-17 63.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98700.1 - 1.4e-09 37.3 0.0 4.1e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_M49 PF03571.10 EGD98701.1 - 3.1e-232 771.5 0.0 5e-232 770.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M49 DUF533 PF04391.7 EGD98702.1 - 0.019 14.3 1.2 0.038 13.3 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) SNF5 PF04855.7 EGD98704.1 - 1.5e-80 270.2 0.0 1.9e-80 269.8 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EGD98704.1 - 0.017 14.4 5.1 0.048 13.0 3.5 1.9 1 0 0 1 1 1 0 GATA zinc finger BHD_1 PF10403.4 EGD98705.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 WD40 PF00400.27 EGD98707.1 - 5.6e-49 162.3 28.7 3.7e-13 48.7 0.5 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EGD98707.1 - 4e-06 26.6 14.7 0.0041 16.8 1.7 4.1 2 2 3 5 5 5 2 Transcription factor IIIC subunit delta N-term Ank_2 PF12796.2 EGD98708.1 - 3e-36 123.6 2.7 1.1e-12 48.0 0.0 4.2 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD98708.1 - 8.6e-30 102.5 5.1 8.3e-10 38.9 0.0 6.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) SPX PF03105.14 EGD98708.1 - 2.4e-25 89.8 5.0 1.6e-18 67.5 1.0 2.4 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 EGD98708.1 - 7.9e-25 85.3 9.1 0.00081 19.0 0.0 8.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 EGD98708.1 - 3.7e-18 63.8 7.7 0.0015 18.5 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 EGD98708.1 - 3.5e-14 52.4 8.8 0.0019 18.4 0.0 6.5 3 1 4 7 7 7 6 Ankyrin repeats (many copies) GDPD PF03009.12 EGD98708.1 - 2.4e-07 30.5 0.0 0.0083 15.6 0.0 2.9 2 1 1 3 3 3 2 Glycerophosphoryl diester phosphodiesterase family SKG6 PF08693.5 EGD98709.1 - 1.4e-08 33.9 5.3 3e-08 32.8 3.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EGD98709.1 - 2e-05 24.1 0.0 4.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EGD98709.1 - 0.0025 17.5 0.1 0.011 15.3 0.1 2.1 1 1 0 1 1 1 1 TMEM154 protein family ASFV_J13L PF05568.6 EGD98709.1 - 0.013 15.0 0.9 0.013 15.0 0.6 2.9 3 2 0 3 3 2 0 African swine fever virus J13L protein Adeno_E3_CR2 PF02439.10 EGD98709.1 - 0.093 12.2 1.1 0.17 11.4 0.8 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 EGD98709.1 - 0.098 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FTHFS PF01268.14 EGD98709.1 - 0.2 9.6 0.2 0.29 9.0 0.2 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase DUF2207 PF09972.4 EGD98709.1 - 0.25 9.8 0.0 0.34 9.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Herpes_gE PF02480.11 EGD98709.1 - 0.26 9.5 0.0 0.26 9.5 0.0 2.6 1 1 2 3 3 3 0 Alphaherpesvirus glycoprotein E Rifin_STEVOR PF02009.11 EGD98709.1 - 0.7 9.4 5.8 0.95 9.0 3.4 1.5 1 1 1 2 2 2 0 Rifin/stevor family MLANA PF14991.1 EGD98709.1 - 7.3 6.6 0.0 7.3 6.6 0.0 3.5 3 1 0 3 3 2 0 Protein melan-A SKG6 PF08693.5 EGD98710.1 - 0.0026 17.0 0.8 0.0049 16.1 0.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sugar_tr PF00083.19 EGD98711.1 - 7.3e-98 328.0 22.8 2.3e-97 326.4 15.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD98711.1 - 2.3e-30 105.5 21.4 2.3e-30 105.5 14.9 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily PspC PF04024.7 EGD98711.1 - 0.028 13.9 3.6 0.028 13.8 0.1 2.9 2 0 0 2 2 2 0 PspC domain MFS_1 PF07690.11 EGD98712.1 - 5.8e-39 133.8 39.5 5.8e-39 133.8 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Guanylate_kin PF00625.16 EGD98713.1 - 2.3e-21 76.0 0.0 2.9e-12 46.4 0.0 2.0 1 1 1 2 2 2 2 Guanylate kinase AAA_22 PF13401.1 EGD98713.1 - 5.7e-05 23.2 0.0 7.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD98713.1 - 0.00011 22.9 0.1 0.00019 22.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD98713.1 - 0.00027 20.9 0.0 0.00031 20.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EGD98713.1 - 0.0006 19.0 0.0 0.00087 18.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EGD98713.1 - 0.0031 17.7 0.9 0.0054 17.0 0.1 1.8 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGD98713.1 - 0.019 14.9 0.0 0.032 14.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 EGD98713.1 - 0.082 12.5 0.0 0.1 12.2 0.0 1.3 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EGD98713.1 - 0.086 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 EGD98713.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.3 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EGD98714.1 - 5.5e-46 156.2 0.9 3.9e-22 79.0 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EGD98714.1 - 2.9e-21 75.1 6.8 2.9e-21 75.1 4.7 3.7 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.1 EGD98714.1 - 5.5e-16 59.3 3.8 0.0007 19.6 0.0 5.0 6 0 0 6 6 6 3 AAA domain SMC_N PF02463.14 EGD98714.1 - 1.7e-11 43.7 0.2 0.0057 15.9 0.0 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGD98714.1 - 2e-08 35.1 0.8 0.0087 16.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EGD98714.1 - 1.6e-06 28.2 1.2 0.0073 16.3 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 EGD98714.1 - 2.4e-06 27.4 0.0 0.066 13.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EGD98714.1 - 1e-05 24.8 0.1 0.052 12.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGD98714.1 - 1.3e-05 25.3 0.1 0.1 12.7 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EGD98714.1 - 1.6e-05 24.3 0.1 0.18 11.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EGD98714.1 - 1.7e-05 25.2 0.4 0.06 13.8 0.0 3.2 3 0 0 3 3 2 2 Miro-like protein AAA_33 PF13671.1 EGD98714.1 - 4.5e-05 23.3 0.1 0.48 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGD98714.1 - 0.0001 22.5 5.9 0.23 11.7 0.0 4.0 5 0 0 5 5 3 2 AAA domain MobB PF03205.9 EGD98714.1 - 0.00011 21.9 0.1 0.51 10.0 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 EGD98714.1 - 0.00026 20.1 12.6 0.92 8.4 0.0 5.3 4 2 2 6 6 6 2 AAA ATPase domain AAA_10 PF12846.2 EGD98714.1 - 0.00035 20.0 0.1 1 8.7 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain AAA_28 PF13521.1 EGD98714.1 - 0.00046 20.1 2.2 0.44 10.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 EGD98714.1 - 0.00051 19.6 0.0 0.03 13.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EGD98714.1 - 0.00081 19.0 0.3 0.9 9.1 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA PF00004.24 EGD98714.1 - 0.0018 18.4 0.1 0.97 9.6 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EGD98714.1 - 0.002 18.4 20.5 0.021 15.1 0.0 4.7 5 0 0 5 5 5 2 AAA domain Dynamin_N PF00350.18 EGD98714.1 - 0.0047 16.7 7.5 0.83 9.4 0.0 3.9 4 1 0 4 4 4 1 Dynamin family Zeta_toxin PF06414.7 EGD98714.1 - 0.0055 15.8 1.8 0.43 9.6 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin Peripla_BP_3 PF13377.1 EGD98714.1 - 0.0059 16.6 0.0 4.4 7.2 0.0 2.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain ArgK PF03308.11 EGD98714.1 - 0.0067 15.2 3.9 0.54 8.9 0.0 2.7 3 0 0 3 3 3 2 ArgK protein SbcCD_C PF13558.1 EGD98714.1 - 0.007 16.2 0.3 5 7.1 0.1 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EGD98714.1 - 0.012 15.8 0.1 7.6 6.7 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_14 PF13173.1 EGD98714.1 - 0.013 15.3 0.1 7.6 6.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EGD98714.1 - 0.015 15.0 0.1 1.8 8.2 0.0 2.9 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 EGD98714.1 - 0.023 14.2 0.1 4.8 6.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EGD98714.1 - 0.042 13.2 0.5 2.8 7.3 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EGD98714.1 - 0.042 13.3 0.1 10 5.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 EGD98714.1 - 0.084 12.6 0.5 14 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF2346 PF09803.4 EGD98714.1 - 8.8 6.2 9.2 0.36 10.7 1.5 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) DUF1409 PF07197.7 EGD98715.1 - 0.083 12.9 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) DUF1279 PF06916.8 EGD98717.1 - 2.7e-28 98.1 0.0 3.7e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L3 PF00297.17 EGD98718.1 - 2.1e-37 128.9 3.3 1.4e-36 126.2 2.3 1.9 1 1 0 1 1 1 1 Ribosomal protein L3 Coa1 PF08695.5 EGD98719.1 - 4e-42 142.4 0.0 4.9e-42 142.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 PigN PF04987.9 EGD98720.1 - 0.0089 14.7 1.9 0.011 14.4 0.1 1.7 1 1 1 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) DUF4231 PF14015.1 EGD98720.1 - 0.042 13.8 0.7 0.15 12.0 0.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) JmjC PF02373.17 EGD98721.1 - 1e-07 32.1 0.8 2.3e-06 27.8 0.5 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EGD98721.1 - 0.00012 22.1 7.0 0.00012 22.1 4.9 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EGD98721.1 - 0.0078 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain UbiA PF01040.13 EGD98722.1 - 8.6e-34 116.9 19.9 1.1e-33 116.5 13.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Flavoprotein PF02441.14 EGD98723.1 - 2.2e-38 130.8 0.0 2.8e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Pkinase PF00069.20 EGD98724.1 - 3.8e-05 22.9 0.0 4.4e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Glutaredoxin PF00462.19 EGD98725.1 - 3.8e-15 55.6 0.0 6.8e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Phasin PF05597.6 EGD98726.1 - 0.091 12.5 0.1 0.091 12.5 0.0 2.5 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CTP_transf_2 PF01467.21 EGD98727.1 - 3.2e-18 66.2 0.1 6.3e-16 58.8 0.0 3.0 3 0 0 3 3 3 2 Cytidylyltransferase PRELI PF04707.9 EGD98729.1 - 6.3e-45 152.5 0.4 7.3e-45 152.3 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family PXA PF02194.10 EGD98730.1 - 6.3e-36 123.6 0.0 1.4e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 EGD98730.1 - 3.4e-18 65.7 0.0 7.6e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 EGD98730.1 - 7.9e-11 41.7 0.0 1.9e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.22 EGD98731.1 - 6.6e-75 246.9 0.9 5.7e-24 83.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EGD98732.1 - 3.7e-12 45.7 0.0 5.4e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD98732.1 - 1.5e-07 31.1 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD98732.1 - 3.1e-07 30.2 0.0 4.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD98732.1 - 0.002 17.8 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EGD98732.1 - 9.8 4.5 18.2 13 4.0 12.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sedlin_N PF04628.8 EGD98733.1 - 6.7e-24 84.2 0.0 8.1e-24 83.9 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Ribosomal_L18e PF00828.14 EGD98734.1 - 7.1e-27 94.3 0.1 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Aldedh PF00171.17 EGD98735.1 - 7.6e-10 37.7 7.0 3.8e-09 35.4 3.2 2.5 2 1 0 2 2 2 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGD98735.1 - 0.025 13.8 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) UDPG_MGDP_dh_N PF03721.9 EGD98735.1 - 0.066 12.5 0.4 0.14 11.5 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PCI PF01399.22 EGD98736.1 - 1.7e-07 31.5 0.0 4.2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain NifU_N PF01592.11 EGD98737.1 - 2.1e-48 163.4 0.0 2.7e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Oxidored_q6 PF01058.17 EGD98738.1 - 7.6e-11 41.7 0.1 1.7e-05 24.4 0.1 2.3 1 1 1 2 2 2 2 NADH ubiquinone oxidoreductase, 20 Kd subunit UDG PF03167.14 EGD98739.1 - 9.2e-26 90.1 0.1 1.4e-25 89.5 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Mucin PF01456.12 EGD98739.1 - 5.3 6.8 26.1 0.18 11.5 11.2 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein UCH PF00443.24 EGD98741.1 - 3.1e-43 147.8 0.0 6.5e-43 146.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGD98741.1 - 1.7e-23 82.5 19.7 9.9e-20 70.4 1.1 3.3 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EGD98741.1 - 8.5e-20 71.3 0.0 1.7e-13 50.6 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EGD98741.1 - 2.5e-14 52.6 0.6 3.6e-07 29.8 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.1 EGD98741.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain FtsJ PF01728.14 EGD98742.1 - 3.4e-60 203.1 0.0 4.1e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EGD98742.1 - 8.8e-06 25.3 0.0 0.081 12.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EGD98742.1 - 0.00011 21.9 0.0 0.00024 20.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD98742.1 - 0.002 18.6 0.0 0.0048 17.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD98742.1 - 0.15 12.5 0.0 15 6.1 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain ThiF PF00899.16 EGD98743.1 - 1.2e-26 93.2 0.0 1.9e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EGD98743.1 - 0.0031 17.6 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EGD98743.1 - 0.012 15.0 0.0 0.063 12.7 0.0 2.1 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EGD98743.1 - 0.052 12.7 0.0 0.26 10.4 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain dCMP_cyt_deam_1 PF00383.17 EGD98744.1 - 3e-27 94.2 2.1 4.6e-27 93.6 1.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 EGD98744.1 - 0.016 14.9 0.2 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase AAA_17 PF13207.1 EGD98744.1 - 0.029 15.2 0.0 0.073 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGD98744.1 - 0.088 13.1 0.0 0.37 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain CoaE PF01121.15 EGD98744.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase His_biosynth PF00977.16 EGD98745.1 - 2.7e-46 157.6 0.7 9.7e-46 155.8 0.5 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EGD98745.1 - 1.7e-31 109.1 0.0 2.7e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EGD98745.1 - 7e-12 45.3 0.0 2.6e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EGD98745.1 - 3.8e-10 39.5 0.0 8.8e-10 38.3 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain BPL_N PF09825.4 EGD98745.1 - 0.01 14.6 0.0 1.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal DJ-1_PfpI PF01965.19 EGD98745.1 - 0.031 13.7 0.0 0.081 12.3 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S51 PF03575.12 EGD98745.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 DNA_pol_E_B PF04042.11 EGD98746.1 - 8.9e-49 165.5 0.1 1.3e-48 165.0 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SHNi-TPR PF10516.4 EGD98747.1 - 4.7e-17 60.9 2.9 8.4e-15 53.7 0.4 2.7 2 0 0 2 2 2 2 SHNi-TPR TPR_12 PF13424.1 EGD98747.1 - 5e-08 32.7 6.0 0.00041 20.2 0.3 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD98747.1 - 3.1e-06 26.7 6.6 7.2e-05 22.3 0.3 3.0 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 EGD98747.1 - 0.00099 19.7 0.2 0.00099 19.7 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGD98747.1 - 0.13 12.2 0.7 1.1 9.3 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF972 PF06156.8 EGD98747.1 - 6.8 7.0 7.3 33 4.8 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Yippee-Mis18 PF03226.9 EGD98748.1 - 4.5e-22 77.8 0.1 5.9e-22 77.5 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EGD98748.1 - 0.0056 16.5 1.3 0.031 14.1 0.9 1.9 1 1 0 1 1 1 1 C-terminal domain of RIG-I Sorting_nexin PF03700.8 EGD98748.1 - 0.045 13.8 0.1 0.086 12.9 0.1 1.4 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain Thioredoxin PF00085.15 EGD98749.1 - 2.2e-56 187.9 8.6 1.1e-27 95.7 0.0 4.5 4 0 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.1 EGD98749.1 - 1.1e-49 168.7 5.1 1.1e-40 139.3 1.1 3.5 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGD98749.1 - 1.8e-10 40.7 0.8 0.0019 18.2 0.0 4.0 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EGD98749.1 - 2.1e-10 40.5 0.0 0.00036 20.4 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EGD98749.1 - 1e-08 35.3 4.5 0.0032 17.6 0.1 4.0 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EGD98749.1 - 2.1e-07 30.6 0.1 0.002 17.8 0.0 3.0 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 EGD98749.1 - 2.5e-05 23.8 2.4 0.06 12.8 0.0 3.1 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.1 EGD98749.1 - 0.044 13.7 4.1 7.5 6.5 0.1 3.6 3 1 0 3 3 3 0 Thioredoxin Med14 PF08638.6 EGD98750.1 - 4.2e-33 114.2 0.0 7.4e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 DWNN PF08783.6 EGD98751.1 - 1.5e-09 37.6 1.4 0.00022 21.0 0.1 2.6 1 1 1 2 2 2 2 DWNN domain zf-CCHC_2 PF13696.1 EGD98751.1 - 1.8e-05 24.0 7.0 5.7e-05 22.5 4.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGD98751.1 - 0.0012 18.6 1.5 0.0012 18.6 1.0 2.0 2 0 0 2 2 2 1 Zinc knuckle DUF3905 PF13045.1 EGD98751.1 - 0.021 14.5 1.4 4.9 6.9 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3905) zf-CCHC_3 PF13917.1 EGD98751.1 - 0.044 13.5 1.9 0.062 13.0 0.2 2.1 2 0 0 2 2 2 0 Zinc knuckle DUF1272 PF06906.6 EGD98751.1 - 0.044 13.6 3.2 0.12 12.2 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) FYVE_2 PF02318.11 EGD98751.1 - 0.14 12.0 1.7 0.36 10.7 1.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4 PF00097.20 EGD98751.1 - 1.5 8.5 8.0 3.6 7.3 5.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGD98751.1 - 3.8 7.4 9.1 11 6.0 6.3 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGD98751.1 - 4.3 7.4 13.1 0.42 10.6 4.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Nucleoporin_C PF03177.9 EGD98752.1 - 5.7e-108 361.9 7.8 7.3e-108 361.6 5.4 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EGD98752.1 - 3.3e-47 161.2 0.0 4.9e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like HABP4_PAI-RBP1 PF04774.10 EGD98753.1 - 0.00015 22.2 2.4 0.00021 21.7 1.7 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family OST3_OST6 PF04756.8 EGD98754.1 - 6.1e-22 77.8 2.5 8.8e-22 77.3 1.7 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EGD98754.1 - 0.022 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin GAS PF13851.1 EGD98755.1 - 9.2e-06 24.9 14.6 2.2e-05 23.7 10.1 1.6 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EGD98755.1 - 0.0055 16.1 7.8 0.032 13.7 0.0 3.1 2 1 0 2 2 2 1 Septum formation initiator Phlebovirus_NSM PF07246.6 EGD98755.1 - 0.0078 15.3 7.3 0.0078 15.3 5.0 1.7 2 0 0 2 2 2 1 Phlebovirus nonstructural protein NS-M DUF2968 PF11180.3 EGD98755.1 - 0.011 15.1 17.3 0.26 10.6 2.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) ADIP PF11559.3 EGD98755.1 - 0.044 13.6 21.5 0.032 14.1 4.7 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.16 EGD98755.1 - 0.05 13.5 0.4 0.05 13.5 0.3 3.1 2 1 0 3 3 2 0 bZIP transcription factor Tropomyosin_1 PF12718.2 EGD98755.1 - 0.12 12.2 14.1 0.36 10.6 9.7 1.9 1 1 0 1 1 1 0 Tropomyosin like CENP-F_leu_zip PF10473.4 EGD98755.1 - 0.13 12.1 20.1 2.1 8.1 13.5 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NYD-SP28_assoc PF14775.1 EGD98755.1 - 0.26 11.0 1.8 20 4.9 0.2 3.0 1 1 2 3 3 3 0 Sperm tail C-terminal domain HALZ PF02183.13 EGD98755.1 - 0.28 10.9 0.1 0.28 10.9 0.0 3.7 3 1 1 4 4 4 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 EGD98755.1 - 0.49 9.5 11.1 0.19 10.8 5.9 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein KxDL PF10241.4 EGD98755.1 - 0.62 10.0 7.9 1.4 8.8 5.3 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein DMPK_coil PF08826.5 EGD98755.1 - 0.97 9.3 11.6 0.62 10.0 3.2 3.0 2 1 0 2 2 2 0 DMPK coiled coil domain like TMPIT PF07851.8 EGD98755.1 - 1.2 8.1 5.9 2.2 7.2 4.1 1.5 1 0 0 1 1 1 0 TMPIT-like protein BLOC1_2 PF10046.4 EGD98755.1 - 1.5 9.0 9.1 2.3 8.4 3.4 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 EGD98755.1 - 1.7 9.0 15.6 5 7.5 3.3 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EGD98755.1 - 1.8 8.8 19.7 1.2 9.5 2.3 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF904) IncA PF04156.9 EGD98755.1 - 2.1 7.9 21.6 7.8 6.0 15.0 1.9 1 1 0 1 1 1 0 IncA protein DUF1843 PF08898.5 EGD98755.1 - 2.6 8.1 6.0 0.43 10.6 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) APG6 PF04111.7 EGD98755.1 - 2.8 6.8 16.8 1.5 7.8 9.2 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Pox_A_type_inc PF04508.7 EGD98755.1 - 3.2 7.7 5.5 46 4.1 0.2 4.2 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat Tnp_P_element PF12017.3 EGD98755.1 - 5 6.2 9.4 3.5 6.8 0.8 2.4 1 1 1 2 2 2 0 Transposase protein IFP_35_N PF07334.8 EGD98755.1 - 5.4 7.0 8.4 13 5.8 0.0 4.0 3 1 1 4 4 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Laminin_II PF06009.7 EGD98755.1 - 5.5 6.7 16.2 0.25 11.0 6.8 2.1 2 1 0 2 2 2 0 Laminin Domain II FUSC PF04632.7 EGD98755.1 - 6.4 5.0 5.2 8.5 4.6 3.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Complex1_LYR PF05347.10 EGD98756.1 - 4.2e-08 32.8 0.1 7.1e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGD98756.1 - 0.00012 22.2 0.2 0.00019 21.5 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like zinc_ribbon_6 PF14599.1 EGD98757.1 - 5.9e-25 86.8 0.5 8.8e-25 86.2 0.4 1.3 1 0 0 1 1 1 1 Zinc-ribbon Rrn6 PF10214.4 EGD98758.1 - 3.8e-101 339.4 1.1 4.9e-101 339.0 0.8 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 EGD98759.1 - 1.8e-23 82.3 0.1 3.1e-22 78.3 0.0 2.5 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF4140 PF13600.1 EGD98759.1 - 0.15 12.5 5.2 2.7 8.4 4.7 2.3 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 EGD98759.1 - 0.24 10.3 14.2 0.34 9.8 9.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2450 PF10475.4 EGD98759.1 - 0.48 9.2 8.9 0.67 8.7 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Cortex-I_coil PF09304.5 EGD98759.1 - 0.84 9.7 18.8 2.2 8.3 4.3 2.5 1 1 1 2 2 2 0 Cortexillin I, coiled coil FUSC PF04632.7 EGD98759.1 - 0.95 7.8 6.8 1.1 7.6 4.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF334 PF03904.8 EGD98759.1 - 1.2 8.3 9.0 1.7 7.9 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) CDC37_N PF03234.9 EGD98759.1 - 6.4 7.0 14.4 80 3.4 10.0 2.1 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding WD40 PF00400.27 EGD98760.1 - 8.6e-33 111.0 12.4 4.8e-12 45.2 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EGD98760.1 - 0.00018 21.3 0.1 0.056 13.1 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGD98760.1 - 0.00062 18.1 0.0 0.0016 16.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nbas_N PF15492.1 EGD98760.1 - 0.00088 18.4 0.3 1.8 7.5 0.0 3.4 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EGD98760.1 - 0.0011 17.2 0.8 0.23 9.5 0.0 2.9 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EGD98760.1 - 0.0091 16.2 0.5 1.6 9.0 0.0 3.7 3 1 0 3 3 3 1 PQQ-like domain Hira PF07569.6 EGD98760.1 - 0.025 13.7 0.0 8.1 5.5 0.0 3.0 2 1 1 3 3 3 0 TUP1-like enhancer of split Nucleoporin_N PF08801.6 EGD98760.1 - 0.07 11.8 0.4 0.49 9.0 0.0 2.1 1 1 0 2 2 2 0 Nup133 N terminal like FG-GAP_2 PF14312.1 EGD98760.1 - 0.1 12.6 0.3 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 FG-GAP repeat Ribosomal_L32p PF01783.18 EGD98761.1 - 1.1e-12 47.8 6.3 1.6e-12 47.4 4.4 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family DZR PF12773.2 EGD98761.1 - 0.002 17.8 0.7 0.0031 17.2 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon Zn_Tnp_IS91 PF14319.1 EGD98761.1 - 0.017 14.5 0.5 0.029 13.8 0.4 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain OrfB_Zn_ribbon PF07282.6 EGD98761.1 - 0.04 13.5 1.6 0.073 12.7 1.0 1.6 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.7 EGD98761.1 - 0.047 13.4 0.4 0.073 12.8 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbons PolC_DP2 PF03833.8 EGD98761.1 - 0.083 10.5 0.3 0.092 10.3 0.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-ribbon_3 PF13248.1 EGD98761.1 - 0.12 11.6 5.1 0.26 10.5 3.5 1.6 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EGD98761.1 - 0.33 10.9 3.4 3.8 7.5 0.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Atg14 PF10186.4 EGD98761.1 - 0.91 8.4 4.4 0.33 9.8 1.4 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 zf-XS PF03470.9 EGD98761.1 - 5.6 7.1 8.7 16 5.6 0.1 3.2 3 0 0 3 3 3 0 XS zinc finger domain Septin PF00735.13 EGD98762.1 - 1.7e-112 375.0 0.7 2e-112 374.7 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EGD98762.1 - 6.5e-07 29.3 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGD98762.1 - 4.1e-06 26.0 0.0 7e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EGD98762.1 - 3.4e-05 23.0 0.0 6.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGD98762.1 - 0.00055 19.7 0.5 1.2 8.8 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EGD98762.1 - 0.00092 18.6 0.4 0.017 14.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EGD98762.1 - 0.0041 16.5 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EGD98762.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGD98762.1 - 0.013 15.7 0.3 0.029 14.6 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EGD98762.1 - 0.015 15.6 0.0 0.025 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGD98762.1 - 0.015 14.1 0.1 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 EGD98762.1 - 0.016 14.1 0.1 0.072 11.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.1 EGD98762.1 - 0.044 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 EGD98762.1 - 0.045 12.8 0.1 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 EGD98762.1 - 0.053 12.9 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EGD98762.1 - 0.1 12.1 0.1 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.2 EGD98762.1 - 0.12 11.4 0.0 12 4.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 Guanylate_kin PF00625.16 EGD98763.1 - 1.1e-62 210.7 0.0 1.3e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 EGD98763.1 - 1.5e-07 31.6 0.0 2.8e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGD98763.1 - 4.8e-06 27.3 0.2 3.3e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGD98763.1 - 1.4e-05 25.2 0.1 4.4e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGD98763.1 - 1.4e-05 25.0 0.1 7.6e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD98763.1 - 1.6e-05 25.2 0.8 0.0003 21.0 0.6 2.3 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EGD98763.1 - 1.7e-05 24.7 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGD98763.1 - 0.00036 19.7 0.0 0.00063 18.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EGD98763.1 - 0.00069 19.9 0.0 0.0015 18.8 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.1 EGD98763.1 - 0.0011 18.8 0.0 0.0026 17.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGD98763.1 - 0.0013 18.6 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGD98763.1 - 0.0019 17.9 0.2 0.0048 16.6 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain AAA_29 PF13555.1 EGD98763.1 - 0.004 16.6 0.1 0.0082 15.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 EGD98763.1 - 0.0049 17.3 0.0 0.0088 16.5 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arch_ATPase PF01637.13 EGD98763.1 - 0.0049 16.5 0.0 0.006 16.3 0.0 1.4 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EGD98763.1 - 0.0053 16.4 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EGD98763.1 - 0.0078 16.3 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.1 EGD98763.1 - 0.011 15.3 0.0 0.034 13.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_10 PF12846.2 EGD98763.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 EGD98763.1 - 0.019 15.1 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGD98763.1 - 0.019 14.6 0.1 0.11 12.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EGD98763.1 - 0.022 15.0 0.1 0.055 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EGD98763.1 - 0.025 13.5 0.0 0.054 12.3 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.4 EGD98763.1 - 0.032 13.2 0.0 0.096 11.6 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EGD98763.1 - 0.034 13.8 0.1 0.071 12.8 0.0 1.8 1 1 0 1 1 1 0 NTPase AAA_25 PF13481.1 EGD98763.1 - 0.041 13.2 0.1 0.37 10.1 0.0 2.3 2 1 1 3 3 3 0 AAA domain KAP_NTPase PF07693.9 EGD98763.1 - 0.043 12.8 0.0 0.043 12.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain cobW PF02492.14 EGD98763.1 - 0.065 12.6 0.0 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.10 EGD98763.1 - 0.085 11.5 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 EGD98763.1 - 0.086 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGD98763.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 EGD98763.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 EGD98763.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Adeno_IVa2 PF02456.10 EGD98763.1 - 0.16 10.5 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein GRAB PF10375.4 EGD98764.1 - 2.1e-07 30.3 0.3 4.4e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EGD98764.1 - 0.0027 16.9 13.1 0.019 14.1 4.3 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EGD98764.1 - 0.032 14.0 14.0 1.4 8.7 4.9 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 EGD98764.1 - 0.42 7.8 51.2 5.7 4.1 35.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) FliJ PF02050.11 EGD98764.1 - 0.63 10.0 49.3 0.066 13.2 13.4 3.7 1 1 2 3 3 3 0 Flagellar FliJ protein GAS PF13851.1 EGD98764.1 - 1.6 7.8 53.0 0.17 11.0 4.3 3.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 EGD98764.1 - 2.8 8.0 28.7 0.85 9.7 1.3 3.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 EGD98764.1 - 3.7 7.8 13.0 9.1 6.6 0.1 4.5 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 EGD98764.1 - 5.3 6.7 55.2 3 7.5 8.0 4.9 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein BSMAP PF12280.3 EGD98765.1 - 0.24 11.2 2.7 0.27 11.1 1.8 1.0 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF4337 PF14235.1 EGD98765.1 - 1.2 8.9 4.3 1.6 8.5 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF814 PF05670.8 EGD98766.1 - 1.3e-12 47.4 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DAO PF01266.19 EGD98768.1 - 6.6e-48 163.4 0.0 1.3e-47 162.4 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGD98768.1 - 4.5e-09 35.8 0.8 4.7e-06 25.9 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD98768.1 - 4.6e-09 35.6 1.1 0.00041 19.3 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EGD98768.1 - 3.7e-05 23.6 0.3 0.0023 17.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGD98768.1 - 0.0004 19.3 0.3 0.013 14.4 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EGD98768.1 - 0.00086 19.0 0.1 0.002 17.8 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EGD98768.1 - 0.0067 15.3 0.0 0.11 11.3 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGD98768.1 - 0.0082 16.1 0.3 0.026 14.5 0.2 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGD98768.1 - 0.01 14.3 0.3 0.018 13.5 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EGD98768.1 - 0.014 15.7 0.1 0.059 13.7 0.1 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGD98768.1 - 0.035 13.1 0.0 0.29 10.1 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_10 PF13460.1 EGD98768.1 - 0.053 13.5 0.2 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 NADH(P)-binding Thi4 PF01946.12 EGD98768.1 - 0.08 12.0 0.3 0.89 8.5 0.1 2.1 2 0 0 2 2 2 0 Thi4 family p450 PF00067.17 EGD98769.1 - 3.5e-64 217.0 0.0 4e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DASH_Dad2 PF08654.5 EGD98770.1 - 6.2e-27 93.6 0.5 7.4e-27 93.3 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 NPV_P10 PF05531.7 EGD98770.1 - 0.019 15.1 0.9 0.031 14.5 0.6 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 EGD98770.1 - 0.02 14.9 1.8 0.021 14.8 0.6 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.7 EGD98770.1 - 0.036 13.8 0.3 0.043 13.6 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 EGD98770.1 - 0.057 13.1 0.2 0.079 12.7 0.2 1.2 1 0 0 1 1 1 0 Laminin Domain II Shugoshin_N PF07558.6 EGD98771.1 - 4.1e-16 58.4 1.2 7.9e-16 57.4 0.8 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EGD98771.1 - 5.6e-09 35.2 9.6 5.6e-09 35.2 6.7 3.2 4 0 0 4 4 4 1 Shugoshin C terminus PPI_Ypi1 PF07491.6 EGD98772.1 - 6.2e-21 73.7 6.0 1.7e-20 72.3 4.2 1.8 1 1 0 1 1 1 1 Protein phosphatase inhibitor PBP1_TM PF14812.1 EGD98772.1 - 0.74 10.1 3.8 1.2 9.5 2.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.8 EGD98772.1 - 0.75 9.3 6.7 0.86 9.1 4.6 1.3 1 1 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 EGD98772.1 - 2.2 6.1 4.5 2.2 6.1 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein ALAD PF00490.16 EGD98773.1 - 4e-118 394.0 0.0 4.6e-118 393.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Hexapep PF00132.19 EGD98774.1 - 4.6e-14 51.1 5.2 4.3e-08 32.3 0.5 3.5 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EGD98774.1 - 6.5e-12 45.2 0.0 1.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.13 EGD98774.1 - 2.8e-10 39.9 8.8 4.9e-10 39.1 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.1 EGD98774.1 - 1.1e-08 34.4 4.9 2.1e-06 27.1 0.4 2.7 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase FAD_binding_3 PF01494.14 EGD98775.1 - 2.1e-16 59.9 0.0 2.8e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EGD98775.1 - 0.00041 19.2 0.0 0.00068 18.5 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EGD98775.1 - 0.00092 18.2 0.1 0.75 8.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EGD98775.1 - 0.02 13.9 1.0 0.14 11.1 0.3 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGD98775.1 - 0.021 14.8 0.1 0.062 13.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGD98775.1 - 0.06 12.1 1.4 0.13 11.0 0.6 1.7 2 0 0 2 2 2 0 FAD binding domain CRM1_C PF08767.6 EGD98776.1 - 8.8e-134 445.4 4.9 8.8e-134 445.4 3.4 3.0 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 EGD98776.1 - 3.7e-42 143.7 9.5 7.1e-42 142.8 4.6 3.1 2 1 1 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EGD98776.1 - 7.1e-12 45.0 0.2 3.1e-11 43.0 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain HD_assoc PF13286.1 EGD98776.1 - 0.027 14.7 3.5 8.9 6.6 0.2 4.3 4 0 0 4 4 4 0 Phosphohydrolase-associated domain CIAPIN1 PF05093.8 EGD98777.1 - 2.7e-35 120.4 3.6 2.7e-35 120.4 2.5 1.7 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Myc_N PF01056.13 EGD98777.1 - 0.031 13.4 0.2 0.044 12.9 0.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Rft-1 PF04506.8 EGD98778.1 - 4.9e-81 272.7 13.1 5.9e-81 272.4 9.1 1.0 1 0 0 1 1 1 1 Rft protein Rep_fac-A_C PF08646.5 EGD98779.1 - 2.6e-48 163.4 7.2 2.1e-46 157.2 3.1 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EGD98779.1 - 5.3e-20 71.0 0.1 1.3e-19 69.8 0.0 1.7 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EGD98779.1 - 1.3e-13 50.5 0.1 2.4e-08 33.7 0.0 4.0 3 1 1 4 4 4 3 OB-fold nucleic acid binding domain DUF2293 PF10056.4 EGD98780.1 - 1.1e-27 95.7 0.1 2.4e-27 94.7 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) DUF605 PF04652.11 EGD98781.1 - 2.3 7.5 7.8 2.5 7.4 5.4 1.2 1 0 0 1 1 1 0 Vta1 like MHYT PF03707.11 EGD98782.1 - 1.2e-08 34.8 17.4 6.1e-06 26.2 0.9 3.7 3 0 0 3 3 3 2 Bacterial signalling protein N terminal repeat Pax2_C PF12403.3 EGD98782.1 - 0.019 14.6 0.0 0.051 13.2 0.0 1.8 1 0 0 1 1 1 0 Paired-box protein 2 C terminal HMA PF00403.21 EGD98783.1 - 1.3e-14 54.0 0.3 1.6e-14 53.7 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Vps4_C PF09336.5 EGD98783.1 - 0.093 12.6 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AHSP PF09236.5 EGD98783.1 - 0.11 12.6 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein Tcp11 PF05794.8 EGD98784.1 - 1.5e-48 165.6 0.4 3.7e-43 147.8 0.3 2.2 2 0 0 2 2 2 2 T-complex protein 11 PXA PF02194.10 EGD98785.1 - 1e-45 155.5 0.0 6.5e-45 152.9 0.0 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EGD98785.1 - 2.1e-29 101.9 0.0 6.8e-29 100.2 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 EGD98785.1 - 4.5e-19 68.3 0.1 1.1e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.14 EGD98785.1 - 4.3e-11 42.9 0.0 1.1e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.27 EGD98787.1 - 3.9e-27 93.1 4.7 2.9e-07 30.1 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat tRNA-synt_1g PF09334.6 EGD98788.1 - 2e-140 467.9 0.0 2.6e-140 467.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGD98788.1 - 1.2e-08 33.4 0.0 5.5e-05 21.3 0.0 3.8 3 1 1 4 4 4 3 tRNA synthetases class I (I, L, M and V) BRF1 PF07741.8 EGD98788.1 - 0.028 14.6 7.0 0.059 13.5 4.9 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Elongin_A PF06881.6 EGD98788.1 - 0.57 10.5 8.4 0.2 12.0 3.7 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A NARP1 PF12569.3 EGD98788.1 - 3.5 6.2 8.0 5.5 5.6 5.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Yae1_N PF09811.4 EGD98789.1 - 1.2e-05 24.7 3.4 2e-05 23.9 2.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal WD40 PF00400.27 EGD98790.1 - 2.7e-50 166.5 23.7 1.4e-12 46.9 0.0 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGD98790.1 - 0.00014 21.3 0.0 0.48 9.9 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EGD98790.1 - 0.12 11.1 0.4 0.2 10.3 0.3 1.3 1 0 0 1 1 1 0 Coatomer WD associated region bZIP_1 PF00170.16 EGD98792.1 - 3e-06 27.0 10.3 2.6e-05 24.0 6.8 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EGD98792.1 - 2.1e-05 24.2 9.8 4.1e-05 23.2 6.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Macoilin PF09726.4 EGD98792.1 - 0.0017 16.7 1.4 0.0017 16.7 0.9 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF972 PF06156.8 EGD98792.1 - 0.05 13.9 0.6 0.096 13.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) FRG2 PF15315.1 EGD98792.1 - 0.089 12.7 6.9 0.16 11.9 4.8 1.4 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Corona_nucleoca PF00937.13 EGD98792.1 - 1 8.2 8.9 1.5 7.6 6.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Striatin PF08232.7 EGD98792.1 - 8.7 6.6 11.3 0.3 11.3 0.3 2.3 1 1 1 2 2 2 0 Striatin family RRM_1 PF00076.17 EGD98793.1 - 4.4e-24 83.8 0.0 6.1e-24 83.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD98793.1 - 2.3e-17 62.7 0.0 3e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD98793.1 - 5.4e-11 42.1 0.9 6.5e-11 41.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGD98793.1 - 0.027 14.2 0.1 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif ChaC PF04752.7 EGD98794.1 - 5.4e-49 166.5 0.1 7e-48 162.9 0.1 2.0 1 1 0 1 1 1 1 ChaC-like protein RHS PF03527.9 EGD98794.1 - 0.048 13.4 0.1 13 5.6 0.0 2.5 2 0 0 2 2 2 0 RHS protein EF-hand_8 PF13833.1 EGD98795.1 - 8.5e-20 70.1 10.8 4e-10 39.1 0.1 4.2 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 EGD98795.1 - 1.5e-19 67.7 11.1 2.2e-07 29.6 0.1 4.3 3 1 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EGD98795.1 - 2.4e-16 59.6 3.8 4e-05 23.6 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EGD98795.1 - 2.7e-16 57.9 4.3 0.00032 20.3 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EGD98795.1 - 1.8e-13 49.1 10.7 5.3e-05 22.3 0.3 4.1 3 1 0 3 3 3 3 EF hand G6PD_C PF02781.11 EGD98796.1 - 1.7e-124 414.4 0.0 2.5e-124 413.9 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EGD98796.1 - 4.1e-26 92.3 0.0 9.1e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Paf1 PF03985.8 EGD98798.1 - 0.021 13.6 2.2 0.02 13.6 1.5 1.0 1 0 0 1 1 1 0 Paf1 Daxx PF03344.10 EGD98798.1 - 0.097 11.1 3.0 0.093 11.2 2.1 1.0 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 EGD98798.1 - 0.44 10.0 5.7 0.57 9.6 3.9 1.1 1 0 0 1 1 1 0 Nucleoplasmin VID27 PF08553.5 EGD98798.1 - 1.3 7.1 5.0 1.4 7.0 3.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein MFS_1 PF07690.11 EGD98799.1 - 4e-45 154.0 55.8 4.4e-44 150.6 38.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD98799.1 - 1e-18 66.9 20.7 2.1e-18 65.9 14.4 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGD98799.1 - 4e-11 42.1 14.9 4e-11 42.1 10.3 3.5 3 2 1 4 4 4 2 Sugar (and other) transporter YfdX PF10938.3 EGD98801.1 - 0.0072 15.9 0.0 0.0086 15.7 0.0 1.1 1 0 0 1 1 1 1 YfdX protein CBS PF00571.23 EGD98802.1 - 0.00023 20.8 0.0 0.76 9.6 0.0 3.3 2 1 0 2 2 2 2 CBS domain Mito_carr PF00153.22 EGD98803.1 - 1.3e-50 169.0 8.8 6.8e-20 70.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S10 PF00450.17 EGD98805.1 - 2.3e-08 33.6 0.0 3.2e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2207 PF09972.4 EGD98805.1 - 0.019 13.5 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RNA_Me_trans PF04252.8 EGD98806.1 - 2.5e-34 118.4 0.0 2.9e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.12 EGD98807.1 - 1.8e-21 75.8 0.1 3.7e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region ICE2 PF08426.5 EGD98808.1 - 2.3e-136 454.6 18.6 2.7e-136 454.4 12.9 1.0 1 0 0 1 1 1 1 ICE2 ABC_membrane_2 PF06472.10 EGD98808.1 - 0.37 9.8 3.8 0.52 9.3 0.1 2.3 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 Fungal_trans PF04082.13 EGD98809.1 - 2.6e-16 59.2 0.5 8.8e-16 57.5 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD98809.1 - 3.5e-07 29.9 17.5 7.1e-07 29.0 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ctr PF04145.10 EGD98809.1 - 0.028 14.4 1.6 0.079 13.0 1.1 1.8 1 0 0 1 1 1 0 Ctr copper transporter family G0-G1_switch_2 PF15103.1 EGD98809.1 - 0.14 12.4 3.7 0.29 11.3 2.6 1.6 1 0 0 1 1 1 0 G0/G1 switch protein 2 MCPVI PF02993.9 EGD98809.1 - 0.21 11.6 9.6 0.37 10.9 6.7 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Hid1 PF12722.2 EGD98809.1 - 1.7 6.2 13.0 2.5 5.6 9.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3533 PF12051.3 EGD98809.1 - 7.2 5.2 10.6 3 6.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) Peptidase_M41 PF01434.13 EGD98810.1 - 3.9e-75 251.9 0.0 9.1e-75 250.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGD98810.1 - 6e-42 142.9 0.0 1.8e-41 141.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EGD98810.1 - 6.7e-09 35.9 1.1 1.7e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.1 EGD98810.1 - 0.00037 20.6 0.3 0.21 11.7 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 EGD98810.1 - 0.0015 18.3 0.1 0.0076 15.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EGD98810.1 - 0.0032 16.8 0.2 0.029 13.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EGD98810.1 - 0.0034 17.1 0.2 0.011 15.4 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGD98810.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 EGD98810.1 - 0.015 14.0 0.1 0.03 13.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_16 PF13191.1 EGD98810.1 - 0.017 15.1 1.7 0.092 12.7 0.1 2.8 2 1 0 3 3 3 0 AAA ATPase domain RuvB_N PF05496.7 EGD98810.1 - 0.021 13.8 0.0 0.051 12.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGD98810.1 - 0.035 14.9 0.6 0.16 12.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGD98810.1 - 0.076 12.9 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pex14_N PF04695.8 EGD98810.1 - 0.27 11.2 9.1 0.12 12.4 0.7 3.1 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1295 PF06966.7 EGD98811.1 - 1.2e-39 135.9 7.8 1.8e-39 135.4 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4181 PF13789.1 EGD98811.1 - 0.021 14.7 0.7 0.021 14.7 0.5 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4181) ICMT PF04140.9 EGD98811.1 - 0.21 11.8 2.7 0.24 11.6 0.0 2.4 2 2 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.15 EGD98812.1 - 1.1e-88 297.7 0.0 1.4e-88 297.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EGD98812.1 - 3e-15 56.0 0.0 5.8e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DUF730 PF05325.6 EGD98813.1 - 0.0052 16.5 0.7 0.088 12.6 0.1 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF730) Glyco_hydro_48 PF02011.10 EGD98813.1 - 0.028 12.5 0.3 0.042 11.9 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 Baculo_PEP_C PF04513.7 EGD98813.1 - 0.034 13.9 21.0 0.38 10.5 3.1 4.9 1 1 5 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.7 EGD98813.1 - 0.055 13.8 14.8 4.7 7.6 0.0 6.8 4 3 0 5 5 5 0 SlyX DUF4149 PF13664.1 EGD98814.1 - 1.9e-25 88.8 0.8 1.9e-25 88.8 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ku PF02735.11 EGD98815.1 - 1.4e-23 83.4 0.0 2.4e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EGD98815.1 - 8e-22 77.7 0.0 2.3e-21 76.2 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EGD98815.1 - 1.5e-14 53.9 0.1 4.6e-14 52.3 0.1 1.8 1 0 0 1 1 1 1 Ku C terminal domain like PX PF00787.19 EGD98816.1 - 2.6e-16 59.3 0.0 7.8e-16 57.8 0.0 1.7 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 EGD98816.1 - 7.1e-08 32.0 3.4 1.5e-07 30.9 2.3 1.6 1 0 0 1 1 1 1 SNARE domain SIP1 PF04938.7 EGD98817.1 - 1.9e-06 27.4 0.0 0.00026 20.4 0.0 2.6 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) tRNA-synt_2 PF00152.15 EGD98818.1 - 4.2e-68 229.6 0.2 4.2e-68 229.6 0.2 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGD98818.1 - 1.2e-06 28.3 0.0 2.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Sin_N PF04801.8 EGD98818.1 - 0.033 13.0 5.2 0.049 12.4 3.6 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region eIF3_subunit PF08597.5 EGD98818.1 - 1.5 8.3 13.9 2.3 7.7 9.6 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Hydrolase_6 PF13344.1 EGD98819.1 - 1.2e-24 86.1 0.0 2.1e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD98819.1 - 1e-13 50.7 0.0 7.3e-13 48.0 0.0 2.3 2 1 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EGD98819.1 - 0.0014 18.8 0.0 1.6 8.9 0.0 2.9 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase DUF4567 PF15131.1 EGD98819.1 - 0.04 14.0 0.1 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4567) F-box-like PF12937.2 EGD98820.1 - 7.9e-11 41.5 0.4 2e-10 40.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD98820.1 - 0.058 13.0 0.4 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.2 EGD98820.1 - 0.058 13.0 0.2 15 5.3 0.0 3.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) COP-gamma_platf PF08752.5 EGD98821.1 - 9.8e-62 207.2 1.4 2e-61 206.2 1.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Adaptin_N PF01602.15 EGD98821.1 - 1.1e-58 198.8 0.0 1.5e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EGD98821.1 - 1.3e-08 34.9 0.0 1.5e-05 25.1 0.0 3.0 1 1 2 3 3 3 2 HEAT repeats Alpha_adaptin_C PF02296.11 EGD98821.1 - 0.00055 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain HEAT_EZ PF13513.1 EGD98821.1 - 0.0038 17.6 0.8 0.013 15.9 0.5 2.0 1 0 0 1 1 1 1 HEAT-like repeat HEAT PF02985.17 EGD98821.1 - 0.0045 16.9 5.3 0.3 11.2 0.2 3.6 4 0 0 4 4 4 2 HEAT repeat HEAT_PBS PF03130.11 EGD98821.1 - 0.058 13.8 0.2 1.3 9.7 0.1 3.3 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat MRP-S35 PF10246.4 EGD98821.1 - 0.09 12.7 0.1 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 Adaptin_N PF01602.15 EGD98822.1 - 6.3e-41 140.2 0.1 8.7e-41 139.8 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EGD98822.1 - 0.00054 20.1 0.1 0.17 12.1 0.1 2.9 2 1 1 3 3 3 2 HEAT repeats Phosducin PF02114.11 EGD98823.1 - 3.8e-15 55.3 0.1 4.6e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Phosducin bZIP_1 PF00170.16 EGD98824.1 - 7.8e-06 25.7 13.1 1.3e-05 25.0 9.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EGD98824.1 - 0.016 15.5 10.7 0.027 14.7 7.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor TMF_TATA_bd PF12325.3 EGD98824.1 - 0.019 14.7 3.6 0.033 13.9 2.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 EGD98824.1 - 0.062 13.6 0.4 0.14 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EGD98824.1 - 0.081 12.7 15.6 0.093 12.5 10.1 1.6 1 1 1 2 2 2 0 Basic region leucine zipper Glutaredoxin2_C PF04399.8 EGD98824.1 - 0.091 12.3 1.5 0.16 11.5 1.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GAS PF13851.1 EGD98824.1 - 0.22 10.7 6.6 0.31 10.2 4.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Bap31 PF05529.7 EGD98824.1 - 5.4 6.4 5.8 7.5 5.9 4.0 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like IncA PF04156.9 EGD98824.1 - 7.2 6.1 5.9 0.75 9.3 1.2 1.5 2 0 0 2 2 2 0 IncA protein Pkinase PF00069.20 EGD98825.1 - 3.1e-38 131.4 0.0 3.9e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98825.1 - 9.6e-14 51.0 0.0 1.3e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD98825.1 - 2.8e-05 23.9 0.0 0.0017 18.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kelch_5 PF13854.1 EGD98826.1 - 6.7e-37 124.8 5.3 1.4e-09 37.6 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EGD98826.1 - 1.2e-31 108.1 14.4 6.7e-08 32.1 0.9 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EGD98826.1 - 2.1e-31 107.3 29.8 2.5e-08 33.8 0.4 7.0 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_1 PF01344.20 EGD98826.1 - 7e-30 102.3 3.8 8.7e-12 44.3 0.2 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EGD98826.1 - 2.1e-24 84.6 9.5 6.6e-11 41.8 0.5 6.3 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EGD98826.1 - 3.7e-23 80.3 7.6 9.3e-09 34.7 0.2 6.4 6 0 0 6 6 6 4 Kelch motif Vac_Fusion PF02346.11 EGD98826.1 - 4.5 6.7 14.2 21 4.6 0.0 5.9 5 1 1 6 6 6 0 Chordopoxvirus fusion protein DUF4396 PF14342.1 EGD98828.1 - 3.1e-45 153.7 1.9 4.1e-45 153.3 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Raptor_N PF14538.1 EGD98829.1 - 2.4e-62 209.3 0.0 4.5e-62 208.4 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EGD98829.1 - 6e-07 29.1 6.8 0.31 11.0 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT PF02985.17 EGD98829.1 - 0.00035 20.3 0.7 0.33 11.1 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 EGD98829.1 - 0.0064 16.7 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 HEAT repeats Atx10homo_assoc PF09759.4 EGD98829.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain DUF1546 PF07571.8 EGD98829.1 - 0.047 13.7 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) zf-RING_2 PF13639.1 EGD98831.1 - 2.6e-14 52.7 5.7 4.1e-14 52.1 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EGD98831.1 - 2.9e-11 42.9 0.0 7.3e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EGD98831.1 - 1.6e-09 37.6 5.3 2.5e-09 36.9 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD98831.1 - 5.1e-09 36.1 2.1 9.7e-09 35.2 1.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGD98831.1 - 1.5e-08 34.1 4.0 2.5e-08 33.4 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD98831.1 - 3.3e-08 33.0 3.3 5e-08 32.4 2.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD98831.1 - 9.3e-08 31.6 3.1 1.5e-07 31.0 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGD98831.1 - 0.0012 18.5 1.1 0.0023 17.7 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGD98831.1 - 0.013 15.1 3.4 0.028 14.1 2.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGD98831.1 - 0.025 14.4 2.5 0.054 13.3 1.8 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EGD98831.1 - 0.049 13.6 2.7 0.12 12.3 1.9 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain DUF2029 PF09594.5 EGD98831.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) RINGv PF12906.2 EGD98831.1 - 0.056 13.5 4.4 0.11 12.6 3.0 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EGD98831.1 - 0.3 10.6 3.1 0.52 9.9 2.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EGD98831.1 - 0.89 9.2 3.4 1.6 8.4 2.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EGD98831.1 - 2.2 8.3 3.8 4.3 7.4 2.7 1.5 1 0 0 1 1 1 0 RING-like domain EI24 PF07264.6 EGD98832.1 - 4.5e-05 22.9 10.0 0.0002 20.9 6.9 1.9 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Nif11 PF07862.6 EGD98832.1 - 0.1 12.5 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function Chitin_bind_1 PF00187.14 EGD98833.1 - 0.0052 16.7 18.9 0.013 15.4 13.1 1.8 1 1 0 1 1 1 1 Chitin recognition protein FAD_binding_3 PF01494.14 EGD98835.1 - 1.4e-13 50.6 0.0 3.7e-13 49.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGD98835.1 - 4.3e-06 25.8 0.2 2.9e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD98835.1 - 4e-05 23.5 0.0 0.00011 22.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGD98835.1 - 0.0011 17.7 0.9 0.0013 17.4 0.1 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EGD98835.1 - 0.012 15.5 0.2 0.027 14.3 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1967 PF09269.6 EGD98835.1 - 0.038 13.6 1.0 0.14 11.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) FAD_oxidored PF12831.2 EGD98835.1 - 0.15 11.0 0.7 0.25 10.3 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EGD98835.1 - 0.17 10.7 0.2 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FHA PF00498.21 EGD98837.1 - 4.2e-16 58.8 0.0 7.7e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain ERM PF00769.14 EGD98837.1 - 0.051 13.1 22.0 0.22 11.0 6.4 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family CENP-Q PF13094.1 EGD98837.1 - 0.51 10.3 27.2 0.19 11.7 4.0 3.3 4 0 0 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit GrpE PF01025.14 EGD98837.1 - 3 7.3 19.0 0.1 12.1 4.0 2.4 2 0 0 2 2 2 0 GrpE MscS_porin PF12795.2 EGD98837.1 - 7.4 5.8 28.7 0.092 12.0 4.8 2.6 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Romo1 PF10247.4 EGD98838.1 - 3.7e-28 97.5 13.9 5.2e-28 97.0 9.6 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_YMGG PF13441.1 EGD98838.1 - 0.21 11.1 2.5 0.3 10.6 1.4 1.6 1 1 0 1 1 1 0 YMGG-like Gly-zipper LysM PF01476.15 EGD98839.1 - 3.3e-24 84.5 0.2 1.4e-07 31.2 0.0 3.2 3 0 0 3 3 3 3 LysM domain HTH_23 PF13384.1 EGD98839.1 - 0.049 13.2 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain Palm_thioest PF02089.10 EGD98839.1 - 0.056 12.3 0.6 11 4.9 0.0 2.7 2 1 1 3 3 3 0 Palmitoyl protein thioesterase Pex14_N PF04695.8 EGD98839.1 - 2.6 8.1 7.8 0.56 10.2 1.8 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LRR_8 PF13855.1 EGD98841.1 - 7.8e-09 35.1 1.5 1.9e-08 33.9 0.5 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 EGD98841.1 - 4e-08 32.7 0.5 4e-08 32.7 0.3 2.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGD98841.1 - 4.6e-06 25.9 1.7 1.1 9.5 0.1 4.2 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EGD98841.1 - 0.0051 16.7 2.9 4.3 7.9 0.0 3.9 4 0 0 4 4 4 2 Leucine rich repeat Arb2 PF09757.4 EGD98842.1 - 1.4e-32 112.5 0.0 2.3e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Hpr_kinase_N PF02603.11 EGD98842.1 - 0.089 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase N terminus Ribosomal_S14 PF00253.16 EGD98843.1 - 2.9e-17 61.7 0.2 1.3e-16 59.6 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e ATP-synt_J PF04911.7 EGD98844.1 - 2.5e-13 49.2 0.1 3.3e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase j chain DASH_Spc19 PF08287.6 EGD98845.1 - 1.9e-49 167.2 3.1 2.5e-49 166.8 2.1 1.2 1 0 0 1 1 1 1 Spc19 COG2 PF06148.6 EGD98845.1 - 0.046 13.5 0.1 0.046 13.5 0.1 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.3 EGD98845.1 - 1.7 8.4 7.9 3 7.7 1.6 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding IFP_35_N PF07334.8 EGD98845.1 - 8.8 6.3 6.4 6.7 6.7 1.5 2.5 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4164 PF13747.1 EGD98845.1 - 8.8 6.5 10.2 6.8 6.8 0.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Rsm22 PF09243.5 EGD98846.1 - 7.3e-29 100.6 0.0 4.3e-28 98.1 0.0 2.1 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Lsr2 PF11774.3 EGD98846.1 - 0.096 12.6 3.4 5.1 7.0 0.4 2.5 2 0 0 2 2 2 0 Lsr2 INTS2 PF14750.1 EGD98846.1 - 0.12 9.9 0.0 0.16 9.4 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 BNR_2 PF13088.1 EGD98847.1 - 4.2e-34 118.1 0.2 5.1e-34 117.8 0.1 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.1 EGD98847.1 - 4.7e-10 39.0 0.0 6.7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 EGD98847.1 - 1.4 9.0 11.6 1.2 9.2 2.3 4.0 3 0 0 3 3 3 0 BNR/Asp-box repeat Rogdi_lz PF10259.4 EGD98848.1 - 1.4e-74 250.6 0.0 1.6e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Mito_fiss_reg PF05308.6 EGD98848.1 - 0.01 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator HSP70 PF00012.15 EGD98849.1 - 4.7e-85 285.7 0.8 4.7e-85 285.7 0.5 2.0 1 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EGD98849.1 - 3e-11 42.4 0.7 4.6e-11 41.9 0.5 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Nucleoplasmin PF03066.10 EGD98849.1 - 0.0057 16.1 1.6 0.013 14.9 1.1 1.6 1 0 0 1 1 1 1 Nucleoplasmin CENP-B_dimeris PF09026.5 EGD98849.1 - 0.015 15.5 2.2 0.034 14.3 1.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PilM_2 PF11104.3 EGD98849.1 - 0.026 13.3 0.3 0.61 8.9 0.0 2.7 1 1 1 2 2 2 0 Type IV pilus assembly protein PilM; Sigma70_ner PF04546.8 EGD98849.1 - 0.29 10.7 6.1 0.2 11.2 2.3 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region FAM176 PF14851.1 EGD98849.1 - 0.96 9.1 4.7 0.21 11.2 0.9 1.7 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.1 EGD98849.1 - 2 8.7 6.7 4 7.8 4.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UAA PF08449.6 EGD98850.1 - 1.3e-09 37.4 21.3 1.6e-09 37.1 14.7 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGD98850.1 - 2.4e-08 33.7 5.8 2.4e-08 33.7 4.0 2.7 1 1 1 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGD98850.1 - 0.0027 17.7 31.7 0.004 17.2 5.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF1077 PF06417.7 EGD98850.1 - 0.034 13.4 5.8 0.47 9.8 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1077) SBP_bac_1 PF01547.20 EGD98850.1 - 0.06 13.0 0.1 10 5.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Tad PF13400.1 EGD98850.1 - 1.2 9.1 4.4 10 6.2 0.7 3.4 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like Rpp20 PF12328.3 EGD98851.1 - 2e-45 153.9 7.5 3.6e-45 153.1 5.2 1.4 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EGD98851.1 - 2.8e-18 65.2 0.9 5.5e-18 64.3 0.7 1.5 1 1 0 1 1 1 1 Alba Cauli_AT PF03233.8 EGD98851.1 - 0.19 11.4 1.2 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Aphid transmission protein CrtC PF07143.6 EGD98852.1 - 0.15 11.3 0.0 0.72 9.0 0.0 1.8 2 0 0 2 2 2 0 Hydroxyneurosporene synthase (CrtC) PhzC-PhzF PF02567.11 EGD98854.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein Retinal PF15449.1 EGD98855.1 - 0.0012 16.6 4.3 0.0014 16.3 3.0 1.0 1 0 0 1 1 1 1 Retinal protein Pacs-1 PF10254.4 EGD98855.1 - 0.14 10.7 0.1 0.17 10.4 0.1 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein UDP-g_GGTase PF06427.6 EGD98857.1 - 1e-67 227.5 0.0 2.3e-67 226.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EGD98857.1 - 0.00022 20.6 0.0 0.00047 19.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Amidohydro_1 PF01979.15 EGD98858.1 - 2.8e-21 76.5 0.0 1.7e-20 73.9 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGD98858.1 - 4.1e-16 59.8 0.0 4.1e-10 40.1 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EGD98858.1 - 1.1e-08 34.7 0.0 2.6e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGD98858.1 - 6.3e-05 22.3 0.0 0.22 10.6 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Glyco_hydro_26 PF02156.10 EGD98858.1 - 0.018 14.5 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 Vma12 PF11712.3 EGD98859.1 - 7.8e-37 126.1 0.0 1.2e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP_synt_I PF03899.10 EGD98859.1 - 0.2 11.8 1.3 0.28 11.3 0.1 1.7 2 0 0 2 2 2 0 ATP synthase I chain Prefoldin PF02996.12 EGD98860.1 - 4.4e-31 107.0 0.1 6.4e-31 106.5 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EGD98860.1 - 0.0015 18.2 0.5 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 Prefoldin subunit DMPK_coil PF08826.5 EGD98860.1 - 0.039 13.8 3.2 0.68 9.8 0.5 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like Mon1 PF03164.9 EGD98860.1 - 0.089 11.3 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 IncA PF04156.9 EGD98860.1 - 0.19 11.3 2.0 0.44 10.1 0.2 2.0 2 0 0 2 2 2 0 IncA protein Glyco_transf_28 PF03033.15 EGD98861.1 - 2.7e-26 91.9 0.0 5.6e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EGD98861.1 - 0.0029 16.2 0.0 0.0043 15.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Prenylcys_lyase PF07156.9 EGD98862.1 - 1.3e-41 142.7 0.0 9.9e-41 139.8 0.0 2.1 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EGD98862.1 - 5e-11 42.4 0.0 1.2e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGD98862.1 - 4.7e-08 32.5 0.0 8.7e-07 28.3 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EGD98862.1 - 0.00025 20.8 0.0 0.034 13.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EGD98862.1 - 0.00073 18.5 0.1 0.014 14.3 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGD98862.1 - 0.0047 16.0 0.2 0.13 11.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EGD98862.1 - 0.0073 16.1 0.2 0.068 13.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_18 PF00704.23 EGD98864.1 - 1.1e-69 235.5 0.1 1.9e-69 234.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DNase_NucA_NucB PF14040.1 EGD98864.1 - 0.031 14.4 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB LysM PF01476.15 EGD98865.1 - 0.0058 16.4 0.0 1.5 8.7 0.0 3.6 4 0 0 4 4 4 2 LysM domain CENP-B_dimeris PF09026.5 EGD98866.1 - 0.041 14.1 7.5 0.099 12.8 5.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_S49_N PF08496.5 EGD98866.1 - 0.26 11.0 0.5 0.37 10.5 0.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sigma70_ner PF04546.8 EGD98866.1 - 0.71 9.4 7.8 1.1 8.8 5.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 EGD98866.1 - 1.1 7.0 8.3 1.5 6.6 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family PDCD2_C PF04194.8 EGD98867.1 - 1.4e-50 171.1 0.4 4.1e-50 169.5 0.0 1.9 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain PCI_Csn8 PF10075.4 EGD98868.1 - 3.4e-43 146.8 0.0 4.7e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EGD98868.1 - 3.9e-22 78.8 0.1 5.2e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Folliculin PF11704.3 EGD98869.1 - 2.3e-44 150.9 0.0 6.5e-44 149.4 0.0 1.8 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport Clp1 PF06807.9 EGD98870.1 - 0.00093 19.0 0.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 AAA_10 PF12846.2 EGD98870.1 - 0.0042 16.5 0.0 0.0082 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain DUF3095 PF11294.3 EGD98870.1 - 0.0061 15.6 0.0 0.0097 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3095) AAA_33 PF13671.1 EGD98870.1 - 0.0064 16.3 0.1 0.088 12.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EGD98870.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGD98870.1 - 0.038 13.9 1.3 0.24 11.3 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EGD98870.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EGD98870.1 - 0.06 13.4 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGD98870.1 - 0.097 12.0 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EGD98870.1 - 0.28 10.1 0.0 1.3 7.9 0.0 1.9 2 0 0 2 2 2 0 Septin RNA_polI_A34 PF08208.6 EGD98871.1 - 3.4e-19 69.3 0.0 3.4e-19 69.3 0.0 2.3 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 SDA1 PF05285.7 EGD98871.1 - 0.0093 15.2 3.6 0.013 14.8 2.5 1.1 1 0 0 1 1 1 1 SDA1 TFIIF_alpha PF05793.7 EGD98871.1 - 0.054 11.8 11.6 0.072 11.4 8.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ndc1_Nup PF09531.5 EGD98871.1 - 0.13 10.7 7.1 0.14 10.5 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.9 EGD98871.1 - 0.63 8.0 6.3 0.73 7.7 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Suf PF05843.9 EGD98871.1 - 1.2 8.7 5.6 1.8 8.2 3.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nop14 PF04147.7 EGD98871.1 - 2.3 6.0 10.7 3.3 5.5 7.4 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 EGD98871.1 - 2.4 7.4 12.5 3.4 6.9 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Macoilin PF09726.4 EGD98871.1 - 9.5 4.3 8.4 13 3.9 5.8 1.2 1 0 0 1 1 1 0 Transmembrane protein SHMT PF00464.14 EGD98872.1 - 4.2e-207 687.2 0.0 5e-207 687.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EGD98872.1 - 5.7e-06 25.5 0.0 1.9e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGD98872.1 - 5.3e-05 22.1 0.0 7.7e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V IL3 PF02059.10 EGD98872.1 - 0.015 15.2 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 Interleukin-3 Beta_elim_lyase PF01212.16 EGD98872.1 - 0.016 14.3 0.0 0.039 13.0 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase DUF3040 PF11239.3 EGD98872.1 - 0.035 14.1 0.2 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) AHH PF14412.1 EGD98872.1 - 0.063 13.2 0.5 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Med9 PF07544.8 EGD98873.1 - 1.1e-22 79.5 0.0 2.1e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 AAA_27 PF13514.1 EGD98873.1 - 0.094 10.3 0.1 0.12 10.0 0.1 1.0 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 EGD98873.1 - 0.13 12.7 0.3 0.21 12.0 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc42p PF11544.3 EGD98873.1 - 0.13 12.1 0.1 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Spindle pole body component Spc42p Med21 PF11221.3 EGD98873.1 - 0.89 9.5 5.1 0.87 9.5 0.1 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Metalloenzyme PF01676.13 EGD98874.1 - 3e-72 243.0 0.0 3.5e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EGD98874.1 - 5.9e-71 238.3 0.0 7.9e-71 237.9 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EGD98874.1 - 1.7e-06 27.5 0.0 4e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGD98874.1 - 0.00033 19.9 0.0 0.011 14.8 0.0 2.5 2 1 0 2 2 2 1 Sulfatase Alk_phosphatase PF00245.15 EGD98874.1 - 0.0097 14.6 0.0 0.061 12.0 0.0 1.9 2 0 0 2 2 2 1 Alkaline phosphatase Prefoldin_2 PF01920.15 EGD98875.1 - 6e-23 80.6 18.1 8.3e-23 80.1 12.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EGD98875.1 - 1.5e-06 27.8 7.5 2.3e-06 27.3 5.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 EGD98875.1 - 0.0003 20.4 21.7 0.019 14.5 15.0 2.0 1 1 0 1 1 1 1 IncA protein Prefoldin PF02996.12 EGD98875.1 - 0.00085 18.9 1.2 0.00085 18.9 0.9 2.4 2 1 0 2 2 2 1 Prefoldin subunit DUF972 PF06156.8 EGD98875.1 - 0.0013 19.0 9.9 0.038 14.3 0.3 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF972) Spc24 PF08286.6 EGD98875.1 - 0.006 16.2 17.2 0.014 15.1 4.9 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.2 EGD98875.1 - 0.01 15.6 18.1 0.23 11.2 5.5 2.1 2 0 0 2 2 2 0 Tropomyosin like Taxilin PF09728.4 EGD98875.1 - 0.011 14.8 11.7 0.023 13.8 2.6 2.0 2 0 0 2 2 2 0 Myosin-like coiled-coil protein SlyX PF04102.7 EGD98875.1 - 0.029 14.7 0.6 0.029 14.7 0.4 2.8 2 1 1 3 3 3 0 SlyX AAA_27 PF13514.1 EGD98875.1 - 0.033 11.8 12.9 0.037 11.7 9.0 1.0 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 EGD98875.1 - 0.036 12.7 13.1 0.045 12.4 9.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Rab5-bind PF09311.6 EGD98875.1 - 0.047 13.5 14.2 0.17 11.7 0.8 2.2 2 0 0 2 2 2 0 Rabaptin-like protein DUF2100 PF09873.4 EGD98875.1 - 0.051 13.0 3.8 0.067 12.6 2.6 1.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) MscS_porin PF12795.2 EGD98875.1 - 0.066 12.5 16.5 0.23 10.7 0.9 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Tropomyosin PF00261.15 EGD98875.1 - 0.066 12.3 15.9 0.062 12.3 1.7 2.0 2 0 0 2 2 2 0 Tropomyosin Myosin_tail_1 PF01576.14 EGD98875.1 - 0.074 10.7 15.2 0.27 8.9 4.4 2.0 2 0 0 2 2 2 0 Myosin tail HDV_ag PF01517.13 EGD98875.1 - 0.081 12.6 2.6 0.16 11.6 1.8 1.5 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen NPV_P10 PF05531.7 EGD98875.1 - 0.086 13.1 11.8 1.3 9.3 2.4 2.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Scaffolding_pro PF11418.3 EGD98875.1 - 0.094 13.0 5.7 1.5 9.1 1.2 2.2 1 1 1 2 2 2 0 Phi29 scaffolding protein DUF3166 PF11365.3 EGD98875.1 - 0.095 13.1 7.6 0.13 12.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) Snapin_Pallidin PF14712.1 EGD98875.1 - 0.1 12.8 9.9 0.12 12.6 0.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin CCDC144C PF14915.1 EGD98875.1 - 0.15 10.9 14.7 0.55 9.0 2.2 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region CENP-F_leu_zip PF10473.4 EGD98875.1 - 0.15 11.9 14.3 0.93 9.3 1.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.4 EGD98875.1 - 0.18 11.7 5.9 2.4 8.1 0.8 2.1 1 1 0 2 2 2 0 Golgi transport complex subunit 5 FliJ PF02050.11 EGD98875.1 - 0.19 11.7 15.9 0.7 9.9 0.3 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DegS PF05384.6 EGD98875.1 - 0.2 10.8 9.5 0.46 9.6 1.6 2.2 2 0 0 2 2 2 0 Sensor protein DegS DUF3584 PF12128.3 EGD98875.1 - 0.21 8.8 12.8 0.28 8.4 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.4 EGD98875.1 - 0.23 11.6 10.4 0.55 10.3 1.6 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lzipper-MIP1 PF14389.1 EGD98875.1 - 0.25 11.4 17.6 0.071 13.2 2.9 3.0 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Mnd1 PF03962.10 EGD98875.1 - 0.25 10.9 17.3 0.45 10.1 4.8 2.0 1 1 1 2 2 2 0 Mnd1 family DUF4201 PF13870.1 EGD98875.1 - 0.33 10.3 13.4 0.5 9.7 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Ded_cyto PF06920.8 EGD98875.1 - 0.38 10.0 9.7 1.4 8.1 0.5 2.0 2 0 0 2 2 2 0 Dedicator of cytokinesis DUF4463 PF14703.1 EGD98875.1 - 0.39 11.2 5.1 0.74 10.3 3.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) Apc4 PF12896.2 EGD98875.1 - 0.48 9.6 4.1 3.1 7.0 1.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 ERp29 PF07749.7 EGD98875.1 - 0.51 11.0 6.8 1.9 9.1 4.7 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Kinetocho_Slk19 PF12709.2 EGD98875.1 - 0.53 10.3 14.8 1.2 9.2 0.5 3.1 2 1 1 3 3 3 0 Central kinetochore-associated COG2 PF06148.6 EGD98875.1 - 0.56 10.0 9.3 1.1 9.0 1.5 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 T2SM PF04612.7 EGD98875.1 - 0.61 9.8 6.0 0.4 10.4 1.4 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M YgaB PF14182.1 EGD98875.1 - 0.64 10.2 17.1 0.18 12.0 3.1 2.4 2 1 0 2 2 2 0 YgaB-like protein CALCOCO1 PF07888.6 EGD98875.1 - 0.79 7.9 11.6 1.1 7.5 8.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like WEMBL PF05701.6 EGD98875.1 - 0.8 8.0 17.1 2.3 6.6 11.9 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Laminin_II PF06009.7 EGD98875.1 - 0.81 9.4 12.0 1.1 9.0 0.8 2.1 1 1 0 2 2 2 0 Laminin Domain II TMPIT PF07851.8 EGD98875.1 - 0.83 8.6 9.7 1.1 8.2 6.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.10 EGD98875.1 - 0.84 9.1 23.6 0.64 9.5 2.1 3.2 2 1 1 3 3 3 0 Septum formation initiator GAS PF13851.1 EGD98875.1 - 0.92 8.6 16.8 0.38 9.9 4.6 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CorA PF01544.13 EGD98875.1 - 1 8.3 7.2 0.19 10.7 0.5 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Pox_F11 PF04943.7 EGD98875.1 - 1 8.1 4.4 1.5 7.5 3.1 1.3 1 1 0 1 1 1 0 Poxvirus F11 protein Occludin_ELL PF07303.8 EGD98875.1 - 1.1 10.0 10.2 1.9 9.2 2.6 2.2 1 1 1 2 2 2 0 Occludin homology domain FemAB PF02388.11 EGD98875.1 - 1.1 7.8 15.8 0.42 9.2 4.5 2.0 1 1 1 2 2 2 0 FemAB family TMF_TATA_bd PF12325.3 EGD98875.1 - 1.1 8.9 17.9 1 9.1 5.0 2.1 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Prominin PF05478.6 EGD98875.1 - 1.1 6.6 6.6 1.3 6.4 4.6 1.0 1 0 0 1 1 1 0 Prominin DUF4164 PF13747.1 EGD98875.1 - 1.2 9.3 12.3 1.3 9.2 4.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) MtrG PF04210.8 EGD98875.1 - 1.2 8.8 4.4 1.1 9.0 1.1 2.3 2 1 0 2 2 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G APG6 PF04111.7 EGD98875.1 - 1.4 7.9 19.6 0.76 8.7 4.8 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 LLC1 PF14945.1 EGD98875.1 - 1.5 9.1 4.7 15 5.9 0.6 2.1 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Rootletin PF15035.1 EGD98875.1 - 1.5 8.7 14.7 2.8 7.9 10.2 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Hemagglutinin PF00509.13 EGD98875.1 - 1.7 6.6 4.2 0.38 8.8 0.4 1.6 2 0 0 2 2 2 0 Haemagglutinin Uds1 PF15456.1 EGD98875.1 - 1.7 8.6 8.9 3.6 7.6 6.1 1.7 1 1 0 1 1 1 0 Up-regulated During Septation DUF3847 PF12958.2 EGD98875.1 - 1.7 8.4 14.2 1.5 8.6 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) EzrA PF06160.7 EGD98875.1 - 1.8 6.6 16.7 0.16 10.0 3.1 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3571 PF12095.3 EGD98875.1 - 1.9 8.7 8.3 5.5 7.3 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) End3 PF12761.2 EGD98875.1 - 2.1 7.9 11.8 3.7 7.1 8.2 1.3 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF948 PF06103.6 EGD98875.1 - 2.2 8.1 9.0 1.4 8.8 0.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-H PF05837.7 EGD98875.1 - 2.4 8.3 10.5 2.5 8.3 1.2 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.7 EGD98875.1 - 2.6 7.8 20.7 4.9 6.8 11.8 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DASH_Dad3 PF08656.5 EGD98875.1 - 2.7 7.7 6.3 6.7 6.4 1.6 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 ERM PF00769.14 EGD98875.1 - 2.9 7.3 19.1 6.2 6.2 13.3 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Dor1 PF04124.7 EGD98875.1 - 3 6.2 8.4 0.68 8.3 2.1 1.8 1 1 0 2 2 2 0 Dor1-like family ACCA PF03255.9 EGD98875.1 - 3.1 7.3 7.8 2.4 7.7 0.6 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2968 PF11180.3 EGD98875.1 - 3.2 7.1 17.2 1.4 8.2 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) AAA_13 PF13166.1 EGD98875.1 - 3.2 6.0 17.8 0.17 10.3 2.5 2.0 1 1 1 2 2 2 0 AAA domain Peptidase_S49_N PF08496.5 EGD98875.1 - 3.4 7.4 10.5 5.5 6.7 7.1 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF1664 PF07889.7 EGD98875.1 - 4.3 7.1 11.4 6.7 6.5 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 EGD98875.1 - 5.1 6.7 12.7 1.6 8.4 1.3 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Sas10_Utp3 PF04000.10 EGD98875.1 - 5.3 7.3 7.7 15 5.8 2.6 2.5 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Vpu PF00558.14 EGD98875.1 - 5.9 6.5 6.2 0.36 10.4 0.5 1.9 2 1 0 2 2 2 0 Vpu protein TBPIP PF07106.8 EGD98875.1 - 6 6.3 17.7 2.8 7.4 2.3 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PspA_IM30 PF04012.7 EGD98875.1 - 6 6.1 18.6 36 3.6 12.9 1.8 1 1 0 1 1 1 0 PspA/IM30 family Allexi_40kDa PF05549.6 EGD98875.1 - 6.1 6.0 6.1 11 5.2 0.8 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF342 PF03961.8 EGD98875.1 - 6.5 5.0 13.9 37 2.5 9.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Osmo_CC PF08946.5 EGD98875.1 - 6.5 6.8 12.8 0.066 13.2 2.6 2.3 2 1 0 2 2 1 0 Osmosensory transporter coiled coil DUF4140 PF13600.1 EGD98875.1 - 6.5 7.2 15.3 6.8 7.2 0.6 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF904 PF06005.7 EGD98875.1 - 7 7.0 15.3 3.4 8.0 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF4200 PF13863.1 EGD98875.1 - 8 6.4 21.1 4 7.4 2.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) AAA PF00004.24 EGD98876.1 - 3.8e-43 146.8 0.0 6.1e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EGD98876.1 - 8e-26 89.7 0.1 3.7e-25 87.5 0.1 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EGD98876.1 - 1.5e-22 79.2 2.0 3.2e-22 78.1 0.9 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EGD98876.1 - 1.2e-05 26.1 0.0 6.7e-05 23.7 0.0 2.2 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 EGD98876.1 - 1.7e-05 23.9 0.0 3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGD98876.1 - 1.9e-05 24.5 0.0 5.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGD98876.1 - 3.2e-05 23.4 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EGD98876.1 - 3.2e-05 23.9 0.0 0.00035 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGD98876.1 - 3.4e-05 23.9 0.2 0.0021 18.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGD98876.1 - 5.8e-05 22.8 0.0 0.00033 20.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EGD98876.1 - 0.00019 20.3 0.0 0.00027 19.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EGD98876.1 - 0.00022 20.7 0.3 0.2 11.0 0.1 3.2 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.1 EGD98876.1 - 0.00022 21.2 0.0 0.0012 18.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EGD98876.1 - 0.00044 20.1 0.0 0.00087 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGD98876.1 - 0.00061 18.7 0.0 0.0055 15.6 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 EGD98876.1 - 0.0022 17.6 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGD98876.1 - 0.0027 17.8 0.0 0.0095 16.0 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_18 PF13238.1 EGD98876.1 - 0.0037 17.5 0.0 0.018 15.3 0.0 2.2 3 0 0 3 3 1 1 AAA domain Arch_ATPase PF01637.13 EGD98876.1 - 0.012 15.3 0.1 0.17 11.5 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase KaiC PF06745.8 EGD98876.1 - 0.013 14.5 0.0 7.3 5.6 0.0 2.9 2 1 1 3 3 3 0 KaiC NACHT PF05729.7 EGD98876.1 - 0.018 14.7 0.0 0.32 10.6 0.0 2.2 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.10 EGD98876.1 - 0.021 14.6 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGD98876.1 - 0.026 14.2 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EGD98876.1 - 0.03 13.4 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EGD98876.1 - 0.033 13.4 0.1 0.093 11.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.7 EGD98876.1 - 0.038 13.0 0.1 0.18 10.8 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin Peptidase_M28 PF04389.12 EGD98876.1 - 0.041 13.6 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M28 Parvo_NS1 PF01057.12 EGD98876.1 - 0.058 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 EGD98876.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Torsin Sigma54_activ_2 PF14532.1 EGD98876.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EGD98876.1 - 0.12 11.7 0.0 0.38 10.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain TPR_1 PF00515.23 EGD98876.1 - 0.15 11.7 0.6 0.52 10.0 0.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_28 PF13521.1 EGD98876.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 EGD98876.1 - 0.16 11.3 0.0 0.4 10.0 0.0 1.7 1 0 0 1 1 1 0 Guanylate kinase Microtub_assoc PF07989.6 EGD98877.1 - 1.7e-25 88.6 6.1 1.7e-25 88.6 4.2 11.7 8 3 5 14 14 14 2 Microtubule associated PACT_coil_coil PF10495.4 EGD98877.1 - 1.9e-09 37.2 1.2 7e-09 35.4 0.9 2.1 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TMF_DNA_bd PF12329.3 EGD98877.1 - 7.9e-09 35.2 14.7 7.9e-09 35.2 10.2 16.0 8 5 7 16 16 16 3 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EGD98877.1 - 0.0085 15.9 15.9 0.0085 15.9 11.0 11.2 3 2 8 11 11 11 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EGD98877.1 - 0.027 12.1 204.0 0.033 11.9 46.8 5.1 2 1 2 5 5 5 0 Myosin tail SGT1 PF07093.6 EGD98878.1 - 1.9e-103 346.9 20.7 9.1e-96 321.5 13.3 3.0 1 1 1 2 2 2 2 SGT1 protein eIF-1a PF01176.14 EGD98878.1 - 0.1 12.0 0.1 1.2 8.5 0.0 2.5 3 0 0 3 3 3 0 Translation initiation factor 1A / IF-1 AMMECR1 PF01871.12 EGD98880.1 - 1.8e-38 131.3 0.0 3.9e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 AMMECR1 Pkinase PF00069.20 EGD98882.1 - 1.2e-69 234.4 0.0 2e-69 233.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD98882.1 - 1.7e-28 99.3 0.0 2.3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD98882.1 - 5.3e-07 28.8 0.0 1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD98882.1 - 0.00027 20.7 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD98882.1 - 0.0011 18.1 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGD98882.1 - 0.036 13.4 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF1744 PF08490.7 EGD98883.1 - 8.4e-143 475.7 1.0 1.2e-142 475.2 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EGD98883.1 - 1.4e-65 221.2 0.4 1.4e-65 221.2 0.3 2.3 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EGD98883.1 - 1.6e-24 86.5 0.0 2.4e-23 82.6 0.1 2.4 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EGD98883.1 - 3.7e-10 39.6 0.1 1.1e-09 38.1 0.1 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EGD98883.1 - 1.6e-05 24.7 0.2 7.5e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily DUF3767 PF12597.3 EGD98884.1 - 2e-35 121.0 0.1 4.6e-35 119.8 0.0 1.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3767) Nop PF01798.13 EGD98886.1 - 1.1e-59 200.0 0.0 2.2e-59 199.0 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGD98886.1 - 1.1e-25 89.2 0.2 2.5e-25 88.0 0.2 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGD98886.1 - 1.4e-20 73.2 0.1 1.4e-20 73.2 0.1 3.1 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RP-C_C PF11800.3 EGD98886.1 - 1.1 8.8 9.7 9.3 5.8 0.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region DDHD PF02862.12 EGD98886.1 - 1.2 8.9 6.5 2.1 8.1 4.5 1.6 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 EGD98886.1 - 2.4 8.0 14.2 4.3 7.2 9.8 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Cpn60_TCP1 PF00118.19 EGD98887.1 - 3e-149 497.7 1.2 3.4e-149 497.5 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.13 EGD98888.1 - 4.2e-55 185.9 0.2 1.3e-51 174.5 0.1 2.1 2 0 0 2 2 2 2 MOZ/SAS family RRM_1 PF00076.17 EGD98889.1 - 1.1e-13 50.6 0.0 1.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD98889.1 - 3.4e-10 39.7 0.0 6.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD98889.1 - 2.2e-05 24.1 0.0 4.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.1 EGD98890.1 - 4.6e-54 183.5 44.8 5.5e-54 183.3 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD98890.1 - 7.1e-20 70.7 36.9 9.8e-20 70.3 25.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.4 EGD98890.1 - 2.6 6.5 9.2 16 3.9 0.6 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Sec23_trunk PF04811.10 EGD98891.1 - 2.4e-44 151.5 0.0 3.7e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGD98891.1 - 1.2e-19 69.6 0.0 2.4e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGD98891.1 - 5.3e-18 65.3 0.0 1.5e-17 63.8 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGD98891.1 - 9.7e-17 60.2 5.5 1.9e-16 59.3 3.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGD98891.1 - 5.6e-07 29.1 0.0 1.2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Fe-ADH PF00465.14 EGD98891.1 - 0.066 11.8 0.1 0.14 10.7 0.0 1.4 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase DUF3954 PF13128.1 EGD98891.1 - 1.1 8.7 3.0 14 5.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3954) Bys1 PF04681.7 EGD98892.1 - 2e-06 27.6 0.2 2.5e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thaumatin PF00314.12 EGD98892.1 - 1.2e-05 24.9 0.8 0.081 12.3 0.0 2.3 1 1 1 2 2 2 2 Thaumatin family Dicty_spore_N PF04562.7 EGD98892.1 - 0.016 15.4 0.1 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Dictyostelium spore coat protein, N terminus ABC_tran PF00005.22 EGD98893.1 - 1.5e-49 167.8 0.1 6.5e-25 88.0 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EGD98893.1 - 2.1e-47 161.0 33.4 5.6e-26 91.0 9.5 2.4 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 EGD98893.1 - 1.5e-15 57.9 6.4 2.5e-08 34.2 1.1 4.5 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EGD98893.1 - 2.3e-10 41.1 0.2 1.5e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EGD98893.1 - 1.1e-09 37.8 0.1 0.22 10.5 0.0 4.1 4 0 0 4 4 4 3 AAA ATPase domain SMC_N PF02463.14 EGD98893.1 - 9.8e-09 34.7 0.7 0.0082 15.4 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EGD98893.1 - 1e-07 31.2 1.9 0.013 14.6 0.9 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGD98893.1 - 9.1e-07 28.4 0.7 0.064 12.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EGD98893.1 - 1e-06 28.3 0.2 0.065 12.9 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 EGD98893.1 - 1.8e-06 28.0 0.1 0.069 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EGD98893.1 - 5.3e-06 27.2 0.1 0.079 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGD98893.1 - 9.3e-06 25.0 3.8 0.082 12.4 0.4 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain NACHT PF05729.7 EGD98893.1 - 1e-05 25.2 0.4 0.022 14.3 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 EGD98893.1 - 1e-05 25.6 0.5 0.098 12.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EGD98893.1 - 1.2e-05 25.1 0.0 0.0029 17.3 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 EGD98893.1 - 0.00025 21.2 0.9 0.86 9.8 0.1 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGD98893.1 - 0.00026 21.0 0.5 0.19 11.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EGD98893.1 - 0.00045 19.7 2.1 0.14 11.6 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EGD98893.1 - 0.00086 19.4 0.2 0.77 9.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 EGD98893.1 - 0.0028 17.9 0.7 2.7 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EGD98893.1 - 0.0032 17.1 1.6 0.63 9.7 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EGD98893.1 - 0.0036 17.8 0.7 1.6 9.2 0.1 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_5 PF07728.9 EGD98893.1 - 0.0073 16.0 0.3 5.8 6.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EGD98893.1 - 0.0085 15.9 0.4 4.2 7.3 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 EGD98893.1 - 0.009 14.9 0.1 1.6 7.5 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 EGD98893.1 - 0.011 15.1 6.6 1 8.6 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EGD98893.1 - 0.012 15.4 0.1 0.91 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGD98893.1 - 0.013 15.0 0.2 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EGD98893.1 - 0.023 14.3 0.7 4.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EGD98893.1 - 0.026 13.6 1.3 5 6.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.7 EGD98893.1 - 0.028 13.7 1.3 4.2 6.5 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_24 PF13479.1 EGD98893.1 - 0.043 13.4 0.5 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EGD98893.1 - 0.045 12.7 0.2 2.9 6.8 0.1 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus ATP-synt_ab PF00006.20 EGD98893.1 - 0.062 12.7 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 EGD98893.1 - 0.071 12.8 1.0 11 5.7 0.2 2.8 3 0 0 3 3 3 0 NTPase IstB_IS21 PF01695.12 EGD98893.1 - 0.086 12.2 0.6 0.78 9.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.4 EGD98893.1 - 0.13 11.7 0.6 16 4.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 EGD98893.1 - 0.18 11.2 0.9 4.7 6.6 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.4 EGD98893.1 - 0.25 10.2 0.4 12 4.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.13 EGD98893.1 - 0.26 10.8 0.9 11 5.4 0.2 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 EGD98893.1 - 0.49 10.3 3.3 2.5 8.0 0.3 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fungal_trans_2 PF11951.3 EGD98894.1 - 5.7e-67 225.9 0.2 8e-67 225.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD98894.1 - 1.2e-09 37.8 10.0 2.2e-09 37.0 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EGD98894.1 - 0.18 11.5 6.6 0.62 9.9 4.6 2.0 1 0 0 1 1 1 0 AT hook motif DUF2434 PF10361.4 EGD98896.1 - 4e-121 403.6 5.7 4.9e-121 403.3 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) DUF2700 PF10912.3 EGD98896.1 - 0.04 13.9 0.2 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2700) Baculo_IE-1 PF05290.6 EGD98896.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) N_methyl_2 PF13544.1 EGD98897.1 - 0.39 10.2 0.0 0.39 10.2 0.0 2.1 2 0 0 2 2 2 0 Type IV pilin N-term methylation site GFxxxE Carn_acyltransf PF00755.15 EGD98901.1 - 0.15 10.1 0.1 0.23 9.5 0.1 1.2 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase DUF2461 PF09365.5 EGD98902.1 - 2.6e-17 62.9 0.4 2.6e-17 62.9 0.3 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) Sporozoite_P67 PF05642.6 EGD98902.1 - 0.3 8.9 6.9 0.41 8.4 4.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FadA PF09403.5 EGD98902.1 - 2.7 8.0 6.8 0.58 10.1 0.2 2.2 2 0 0 2 2 2 0 Adhesion protein FadA TYW3 PF02676.9 EGD98903.1 - 5e-65 218.4 0.0 7.2e-65 217.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 ARPC4 PF05856.7 EGD98905.1 - 1.5e-75 252.2 3.5 1.7e-75 252.0 2.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.24 EGD98906.1 - 1.1e-54 185.3 0.6 1.5e-54 184.9 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD98906.1 - 4e-17 62.5 6.2 1.7e-16 60.5 4.3 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EGD98906.1 - 1.8e-11 43.2 0.0 4.1e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EGD98906.1 - 0.069 13.4 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain RILP PF11461.3 EGD98906.1 - 0.55 10.4 0.0 0.55 10.4 0.0 3.4 3 1 0 3 3 3 0 Rab interacting lysosomal protein 4HBT PF03061.17 EGD98907.1 - 1e-06 28.7 0.0 2.5e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EGD98907.1 - 0.017 15.0 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) WD40 PF00400.27 EGD98908.1 - 2.2e-14 52.6 11.1 9.4e-05 22.1 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.17 EGD98908.1 - 0.00096 19.0 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-C3HC4_2 PF13923.1 EGD98908.1 - 0.023 14.7 12.0 0.063 13.3 8.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UQ_con PF00179.21 EGD98909.1 - 5.9e-47 158.6 0.0 6.7e-47 158.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD98909.1 - 0.00022 21.0 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGD98909.1 - 0.0096 15.6 0.1 0.019 14.6 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EGD98909.1 - 0.01 15.6 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain Ribosomal_L24e PF01246.15 EGD98910.1 - 3.9e-31 106.7 0.3 3.9e-31 106.7 0.2 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e EVC2_like PF12297.3 EGD98910.1 - 0.18 10.3 3.7 0.22 10.1 2.6 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Ribosomal_S30 PF04758.9 EGD98911.1 - 1.4e-29 101.5 7.8 1.6e-29 101.3 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Acetyltransf_7 PF13508.1 EGD98912.1 - 1.3e-10 41.2 0.2 1.9e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD98912.1 - 6.9e-10 38.8 0.1 1.3e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EGD98912.1 - 0.00014 22.0 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD98912.1 - 0.0098 15.7 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Thiolase_C PF02803.13 EGD98912.1 - 0.12 11.7 0.0 3.9 6.9 0.0 2.6 3 0 0 3 3 3 0 Thiolase, C-terminal domain DUF4115 PF13464.1 EGD98913.1 - 0.021 14.4 0.0 0.055 13.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4115) Lyase_1 PF00206.15 EGD98914.1 - 6.5e-106 354.0 0.0 1e-105 353.4 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EGD98914.1 - 1.5e-22 79.3 0.0 3.4e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Abhydrolase_3 PF07859.8 EGD98915.1 - 2.4e-49 167.8 0.1 3.2e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD98915.1 - 0.00011 21.4 0.0 0.00026 20.2 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EGD98915.1 - 0.001 17.8 0.4 0.003 16.3 0.3 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EGD98915.1 - 0.0071 16.1 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EGD98915.1 - 0.025 13.8 0.1 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase AP_endonuc_2 PF01261.19 EGD98915.1 - 0.096 11.9 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel FMO-like PF00743.14 EGD98916.1 - 6.2e-99 331.6 0.0 8.2e-99 331.1 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGD98916.1 - 2.1e-23 83.4 0.0 5e-23 82.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD98916.1 - 5.3e-10 38.7 0.0 1.4e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGD98916.1 - 1.1e-08 35.0 0.0 3.2e-05 23.7 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGD98916.1 - 2.6e-05 24.1 0.0 6.7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGD98916.1 - 0.00061 19.7 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD98916.1 - 0.0024 18.2 0.5 0.13 12.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 EGD98917.1 - 2.8e-68 230.5 0.0 3.4e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 EGD98918.1 - 3.4e-89 299.3 33.4 4.1e-89 299.0 23.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD98918.1 - 4.9e-18 64.7 28.5 1.1e-17 63.6 19.7 1.5 1 1 0 1 1 1 1 Amino acid permease Myb_DNA-binding PF00249.26 EGD98919.1 - 2.1e-27 94.9 8.6 2.8e-10 40.0 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD98919.1 - 2.3e-27 94.8 11.6 5.6e-15 55.1 0.4 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGD98919.1 - 0.023 14.8 11.7 0.33 11.1 0.5 3.7 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Complex1_30kDa PF00329.14 EGD98920.1 - 4.7e-36 123.1 0.1 8.3e-36 122.3 0.1 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.1 EGD98921.1 - 5.5e-19 67.4 13.4 1.1e-18 66.5 9.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EGD98921.1 - 5.3e-05 22.8 7.2 9.2e-05 22.0 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 EGD98921.1 - 0.00019 20.9 0.0 0.00045 19.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 EGD98921.1 - 0.0018 18.0 5.0 0.0035 17.0 3.4 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_5 PF13893.1 EGD98921.1 - 0.0035 17.1 0.0 0.0087 15.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EGD98921.1 - 0.19 11.4 12.7 0.37 10.4 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD98921.1 - 1.2 9.2 11.9 2.3 8.3 8.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) E1_dh PF00676.15 EGD98922.1 - 3.4e-90 301.8 0.3 4.1e-90 301.5 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EGD98922.1 - 0.00047 19.7 0.2 0.0017 17.9 0.1 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 EGD98922.1 - 0.00054 18.8 1.6 0.0011 17.8 0.0 1.8 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 EGD98922.1 - 0.01 14.7 0.0 0.027 13.3 0.0 1.5 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.5 EGD98922.1 - 0.052 12.0 0.0 0.15 10.6 0.0 1.7 2 0 0 2 2 2 0 XFP N-terminal domain DUF217 PF02697.9 EGD98922.1 - 0.14 12.3 1.1 12 6.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 Ubie_methyltran PF01209.13 EGD98923.1 - 2.6e-77 259.0 0.0 4.4e-77 258.3 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGD98923.1 - 7.3e-15 54.8 0.0 9.7e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD98923.1 - 2.7e-13 50.2 0.0 4.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD98923.1 - 1.4e-10 41.5 0.0 2.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD98923.1 - 1.5e-09 38.0 0.0 3.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD98923.1 - 1.1e-08 35.6 0.0 1.9e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD98923.1 - 1.8e-08 34.3 0.0 2.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD98923.1 - 3.8e-05 23.6 0.0 8.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EGD98923.1 - 0.044 13.4 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_24 PF13578.1 EGD98923.1 - 0.12 13.2 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SIS PF01380.17 EGD98924.1 - 2.7e-12 46.4 0.0 1.1e-11 44.5 0.0 2.0 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EGD98924.1 - 1.8e-05 24.4 0.0 4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 SIS domain CheX PF13690.1 EGD98924.1 - 0.12 12.2 1.1 4.6 7.1 0.1 2.8 3 0 0 3 3 3 0 Chemotaxis phosphatase CheX RNA_pol_L_2 PF13656.1 EGD98924.1 - 0.14 11.5 0.0 0.37 10.2 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain BUD22 PF09073.5 EGD98925.1 - 1.3e-90 304.5 22.1 1.6e-90 304.2 15.3 1.1 1 0 0 1 1 1 1 BUD22 PNP_UDP_1 PF01048.15 EGD98926.1 - 1.5e-36 125.5 0.0 1.9e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Glyco_hydro_3 PF00933.16 EGD98927.1 - 4.9e-66 222.7 0.0 5.2e-64 216.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGD98927.1 - 7.2e-55 185.9 0.1 3.1e-54 183.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGD98927.1 - 2.2e-18 65.9 0.2 4.2e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF572 PF04502.8 EGD98928.1 - 2e-51 175.1 0.3 3.7e-51 174.2 0.2 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF572) PTPA PF03095.10 EGD98929.1 - 2.3e-110 368.4 0.0 2.7e-110 368.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein AAA_13 PF13166.1 EGD98931.1 - 0.00011 20.9 36.9 0.00011 20.9 25.6 6.0 1 1 4 5 5 5 2 AAA domain Filament PF00038.16 EGD98931.1 - 0.00031 20.3 164.8 0.084 12.3 37.0 4.9 2 1 3 5 5 5 3 Intermediate filament protein CENP-F_leu_zip PF10473.4 EGD98931.1 - 0.00074 19.3 25.3 0.00074 19.3 17.6 9.3 2 1 6 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 EGD98931.1 - 0.0083 15.9 33.4 0.0083 15.9 23.1 9.3 2 1 7 9 9 9 5 Tropomyosin like DUF3584 PF12128.3 EGD98931.1 - 8.6 3.5 182.7 0.0016 15.8 30.2 5.1 1 1 4 5 5 5 0 Protein of unknown function (DUF3584) Rad4 PF03835.10 EGD98932.1 - 1.1e-35 122.1 0.0 2.2e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EGD98932.1 - 6.7e-28 96.2 0.0 3.2e-27 94.0 0.0 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EGD98932.1 - 2.3e-19 68.6 0.1 4.6e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EGD98932.1 - 5.9e-15 55.3 0.3 5.9e-15 55.3 0.2 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EGD98932.1 - 0.038 14.2 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 Transglutaminase-like superfamily SapC PF07277.6 EGD98932.1 - 0.24 10.7 0.0 0.43 9.8 0.0 1.3 1 0 0 1 1 1 0 SapC BSD PF03909.12 EGD98934.1 - 5.1e-16 58.1 0.8 1.4e-15 56.7 0.6 1.8 1 0 0 1 1 1 1 BSD domain Suf PF05843.9 EGD98934.1 - 0.088 12.5 1.8 0.13 12.0 1.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EGD98934.1 - 3.3 7.8 5.3 1.4 8.9 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat USP7_ICP0_bdg PF12436.3 EGD98935.1 - 5.5e-40 137.1 0.0 9.1e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 EGD98935.1 - 8.1e-36 123.5 0.2 1.1e-35 123.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD98935.1 - 8.8e-16 58.1 0.0 1.6e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EGD98935.1 - 1e-07 32.2 0.1 4.2e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 MATH domain Ran-binding PF05508.6 EGD98936.1 - 1.7e-104 348.9 0.0 3.3e-91 305.3 0.0 2.1 1 1 1 2 2 2 2 RanGTP-binding protein CTP_transf_2 PF01467.21 EGD98937.1 - 4.4e-26 91.8 0.0 5.9e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase GTP_EFTU PF00009.22 EGD98938.1 - 3.5e-42 143.9 0.0 5.1e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGD98938.1 - 4.9e-21 74.7 0.1 9.7e-21 73.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGD98938.1 - 1e-08 35.1 0.3 2.4e-08 33.9 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGD98938.1 - 0.0036 17.2 0.0 0.0089 15.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGD98938.1 - 0.025 13.2 0.2 0.054 12.1 0.1 1.6 1 0 0 1 1 1 0 G-protein alpha subunit Aminotran_1_2 PF00155.16 EGD98939.1 - 3e-40 138.2 0.0 3.8e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGD98939.1 - 0.052 12.2 0.0 0.64 8.6 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGD98939.1 - 0.07 11.4 0.0 0.1 10.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.16 EGD98940.1 - 1.8e-42 145.3 0.0 8.4e-22 77.4 0.0 2.4 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EGD98940.1 - 1.2e-32 113.1 0.0 1.9e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain BATS PF06968.8 EGD98941.1 - 9.8e-28 95.8 0.0 3.3e-27 94.1 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EGD98941.1 - 4.5e-16 59.4 0.0 8.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily GST_N_3 PF13417.1 EGD98943.1 - 8.4e-10 38.7 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD98943.1 - 1.2e-09 38.0 0.0 2.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD98943.1 - 8.1e-08 32.3 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD98943.1 - 2.1e-06 27.6 0.1 4.7e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGD98943.1 - 0.00066 19.5 0.2 0.0012 18.7 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD98943.1 - 0.0028 18.1 0.0 0.0047 17.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.13 EGD98944.1 - 1.4e-48 165.2 0.0 2e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EGD98944.1 - 6e-25 87.3 0.0 1.2e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.8 EGD98945.1 - 1.5e-158 527.6 0.0 1.8e-158 527.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase TPR_17 PF13431.1 EGD98946.1 - 0.0069 16.5 0.2 0.098 12.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGD98946.1 - 0.021 14.4 0.6 0.19 11.4 0.1 2.3 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 EGD98946.1 - 0.11 13.1 0.7 0.5 11.1 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase PF00903.20 EGD98947.1 - 6.8e-25 87.5 0.9 1e-17 64.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EGD98947.1 - 2e-15 56.7 0.2 7.1e-08 32.4 0.2 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGD98947.1 - 1.6e-12 47.9 0.0 1.8e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EGD98947.1 - 1.1e-07 31.9 0.1 0.00096 19.1 0.1 2.9 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EGD98947.1 - 0.00022 21.1 0.2 0.0043 17.0 0.2 2.4 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal COX15-CtaA PF02628.10 EGD98948.1 - 5.4e-79 265.2 7.0 7.7e-79 264.6 4.8 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PQ-loop PF04193.9 EGD98948.1 - 0.047 13.2 0.6 11 5.6 0.1 3.0 2 0 0 2 2 2 0 PQ loop repeat Prok-RING_2 PF14445.1 EGD98949.1 - 0.093 12.6 5.6 0.16 11.9 3.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-RING_4 PF14570.1 EGD98949.1 - 0.12 11.9 4.1 0.25 10.9 2.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RanBP PF00641.13 EGD98949.1 - 0.62 9.2 9.8 0.016 14.2 2.3 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others tRNA-synt_2 PF00152.15 EGD98950.1 - 7.9e-91 304.3 0.6 1.1e-90 303.8 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGD98950.1 - 4.2e-12 45.7 0.0 1.2e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGD98950.1 - 3.5e-06 26.3 0.1 0.0071 15.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) SUKH-3 PF14433.1 EGD98950.1 - 0.073 12.8 0.1 8.6 6.1 0.0 2.5 2 0 0 2 2 2 0 SUKH-3 immunity protein Dynamin_N PF00350.18 EGD98951.1 - 5.4e-24 84.8 0.0 2.3e-23 82.8 0.0 2.1 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGD98951.1 - 3.5e-06 26.0 0.0 0.00042 19.1 0.0 2.8 3 0 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.18 EGD98951.1 - 0.00071 19.5 0.0 0.018 14.9 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EGD98951.1 - 0.0014 19.1 0.0 0.0046 17.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 EGD98951.1 - 0.1 11.9 0.1 0.26 10.6 0.1 1.7 1 0 0 1 1 1 0 Ras family NTP_transferase PF00483.18 EGD98952.1 - 5.3e-29 101.2 0.0 7e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EGD98952.1 - 2.6e-09 36.1 8.7 1.1e-06 27.8 0.1 3.9 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EGD98952.1 - 5.4e-08 33.0 0.0 8.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EGD98952.1 - 0.0085 15.6 0.0 0.028 13.9 0.0 1.7 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.1 EGD98952.1 - 0.091 12.3 3.6 0.25 10.9 0.0 3.0 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Glycos_transf_2 PF00535.21 EGD98952.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Bys1 PF04681.7 EGD98953.1 - 3.1e-12 46.4 0.1 3.5e-12 46.3 0.1 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Pyridox_oxidase PF01243.15 EGD98956.1 - 1.5e-08 34.5 0.0 0.0008 19.3 0.0 2.9 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 EGD98956.1 - 2e-06 27.8 0.0 0.00044 20.3 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain zf-RING_2 PF13639.1 EGD98957.1 - 6.3e-09 35.5 3.9 1e-08 34.8 2.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGD98957.1 - 1.5e-05 25.0 1.7 3.9e-05 23.6 1.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGD98957.1 - 0.00018 21.3 0.8 0.00028 20.6 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EGD98957.1 - 0.0012 18.7 1.3 0.0026 17.7 0.9 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EGD98957.1 - 0.02 14.8 0.2 0.049 13.6 0.1 1.6 1 0 0 1 1 1 0 zinc-finger zf-C3HC4_3 PF13920.1 EGD98957.1 - 0.04 13.5 2.7 0.35 10.5 1.7 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Atx10homo_assoc PF09759.4 EGD98958.1 - 2.6e-30 104.1 1.6 5.8e-30 103.0 0.3 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain zf-DHHC PF01529.15 EGD98959.1 - 5.3e-31 107.3 5.5 9e-31 106.5 3.8 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase LRV_FeS PF05484.6 EGD98959.1 - 0.37 10.3 4.1 0.68 9.5 2.8 1.4 1 0 0 1 1 1 0 LRV protein FeS4 cluster Rap1_C PF11626.3 EGD98960.1 - 3.2e-24 84.6 0.1 8.8e-23 80.0 0.0 2.4 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EGD98960.1 - 1.5e-19 69.5 0.8 1.5e-19 69.5 0.6 2.8 2 1 1 3 3 3 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EGD98960.1 - 5.6e-09 36.4 7.0 6.2e-06 26.7 0.2 3.1 3 1 0 3 3 3 2 Rap1, DNA-binding BRCT PF00533.21 EGD98960.1 - 0.044 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Chromo_shadow PF01393.14 EGD98961.1 - 2.1e-13 49.8 0.0 1.8e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 EGD98961.1 - 4.2e-13 48.7 0.1 1.1e-12 47.4 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DNA_pol_phi PF04931.8 EGD98961.1 - 5.9 4.5 11.5 6.4 4.4 8.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cpn60_TCP1 PF00118.19 EGD98962.1 - 4.1e-148 494.0 3.3 4.7e-148 493.8 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 EGD98962.1 - 0.014 15.3 2.5 4.4 7.2 0.0 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain DUF3295 PF11702.3 EGD98966.1 - 5.1e-123 411.7 38.9 5.1e-123 411.7 27.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EGD98966.1 - 7.9e-12 44.5 2.3 1.8e-11 43.3 1.6 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ParBc PF02195.13 EGD98966.1 - 0.028 14.5 0.2 0.65 10.1 0.0 3.1 4 0 0 4 4 4 0 ParB-like nuclease domain Polysacc_deac_1 PF01522.16 EGD98969.1 - 3.9e-21 74.9 0.0 2.2e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide deacetylase RWD PF05773.17 EGD98970.1 - 0.0028 17.5 0.1 0.37 10.7 0.0 2.5 2 0 0 2 2 2 2 RWD domain zf-DNA_Pol PF08996.5 EGD98970.1 - 0.0087 15.4 2.7 2.1 7.6 0.2 2.3 2 0 0 2 2 2 2 DNA Polymerase alpha zinc finger DUF2183 PF09949.4 EGD98970.1 - 0.15 11.9 0.0 3.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) zf-CHY PF05495.7 EGD98970.1 - 6.3 7.0 12.5 11 6.3 0.2 3.8 3 0 0 3 3 3 0 CHY zinc finger Pox_MCEL PF03291.11 EGD98972.1 - 3.1e-56 190.6 0.0 2.2e-53 181.2 0.0 3.7 1 1 0 1 1 1 1 mRNA capping enzyme Rsm1 PF08600.5 EGD98972.1 - 1.7e-23 82.2 0.0 1.3e-22 79.4 0.0 2.7 1 0 0 1 1 1 1 Rsm1-like zf-C3HC PF07967.8 EGD98972.1 - 4.6e-21 74.9 2.2 4.3e-19 68.6 0.1 4.2 3 1 1 4 4 4 1 C3HC zinc finger-like zf-Nse PF11789.3 EGD98972.1 - 3e-20 71.4 1.8 5.6e-20 70.6 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Methyltransf_12 PF08242.7 EGD98972.1 - 2.8e-08 34.1 2.9 2.5e-07 31.1 0.0 4.0 3 2 1 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD98972.1 - 9.8e-07 29.1 0.0 0.12 12.8 0.0 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EGD98972.1 - 1.2e-05 25.8 0.0 3.6e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD98972.1 - 0.00022 20.8 0.0 0.19 11.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain zf-RING_2 PF13639.1 EGD98972.1 - 0.00023 20.9 0.8 0.00052 19.7 0.6 1.7 1 0 0 1 1 1 1 Ring finger domain Methyltransf_25 PF13649.1 EGD98972.1 - 0.00076 19.8 0.0 0.0029 17.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EGD98972.1 - 0.00084 18.3 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family zf-RING_UBOX PF13445.1 EGD98972.1 - 0.0025 17.5 1.2 0.0087 15.7 0.9 2.1 1 0 0 1 1 1 1 RING-type zinc-finger Mito_carr PF00153.22 EGD98973.1 - 7.3e-41 137.7 0.9 7.5e-21 73.6 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3611 PF12263.3 EGD98973.1 - 0.03 13.7 0.5 0.056 12.8 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3611) Meiotic_rec114 PF03525.9 EGD98975.1 - 8.1e-05 21.2 0.0 0.0037 15.8 0.0 2.4 2 0 0 2 2 2 2 Meiotic recombination protein rec114 HS1_rep PF02218.10 EGD98975.1 - 0.014 15.2 1.9 0.031 14.1 1.3 1.5 1 0 0 1 1 1 0 Repeat in HS1/Cortactin Transp_cyt_pur PF02133.10 EGD98976.1 - 8.6e-39 133.3 7.6 1.3e-19 70.1 0.7 2.9 1 1 2 3 3 3 3 Permease for cytosine/purines, uracil, thiamine, allantoin Tfb2 PF03849.9 EGD98977.1 - 5.3e-136 453.0 0.0 6.2e-136 452.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EGD98977.1 - 6.7e-06 25.8 0.0 4.4e-05 23.2 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SinI PF08671.5 EGD98977.1 - 0.019 14.3 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 Anti-repressor SinI PhzC-PhzF PF02567.11 EGD98979.1 - 1.9e-42 145.4 0.5 5.2e-42 144.0 0.4 1.6 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein TIMELESS PF04821.9 EGD98980.1 - 3e-90 302.0 0.4 8.2e-90 300.6 0.0 2.0 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 EGD98980.1 - 9.7e-40 137.0 11.6 7.9e-37 127.4 0.0 3.6 2 1 1 3 3 3 3 Timeless protein C terminal region 3HCDH_N PF02737.13 EGD98981.1 - 4.3e-52 176.3 0.8 5.7e-52 175.9 0.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EGD98981.1 - 2e-34 117.8 0.0 4.4e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGD98981.1 - 3.4e-05 23.7 0.4 8.4e-05 22.4 0.2 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EGD98981.1 - 0.00021 20.7 0.1 0.0095 15.3 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EGD98981.1 - 0.00022 20.9 0.1 0.00034 20.3 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EGD98981.1 - 0.0023 16.9 0.1 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGD98981.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EGD98981.1 - 0.0088 14.9 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase F420_oxidored PF03807.12 EGD98981.1 - 0.021 15.2 1.5 0.071 13.5 0.9 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 EGD98981.1 - 0.039 14.3 0.1 0.094 13.1 0.0 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EGD98981.1 - 0.061 12.4 0.9 0.67 9.0 0.6 2.1 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGD98981.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 EGD98981.1 - 0.076 12.8 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Actin PF00022.14 EGD98984.1 - 5.5e-104 347.7 0.0 6.4e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGD98984.1 - 0.13 10.8 0.0 2.4 6.6 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein GCIP PF13324.1 EGD98985.1 - 1.7e-10 40.6 1.9 2.6e-10 40.0 1.3 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.8 EGD98985.1 - 0.0052 16.4 0.9 0.0096 15.5 0.7 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region RXT2_N PF08595.6 EGD98985.1 - 0.036 13.8 1.3 0.081 12.7 0.9 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal LRR_4 PF12799.2 EGD98986.1 - 3.1e-33 112.8 48.7 6.3e-08 32.0 0.7 11.1 8 2 3 12 12 12 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD98986.1 - 1.8e-28 98.0 44.5 2.5e-07 30.3 1.6 8.3 5 2 1 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 EGD98986.1 - 1.8e-14 51.5 38.6 0.13 12.3 0.0 16.1 15 2 2 17 17 17 4 Leucine Rich Repeat LRR_7 PF13504.1 EGD98986.1 - 1.7e-11 42.3 38.6 0.35 11.2 0.1 15.4 17 0 0 17 17 17 4 Leucine rich repeat LRR_6 PF13516.1 EGD98986.1 - 1.7e-05 24.3 35.9 1.1 9.5 0.1 12.6 15 0 0 15 15 15 2 Leucine Rich repeat LRR_9 PF14580.1 EGD98986.1 - 0.00066 19.2 11.5 0.078 12.5 0.2 3.6 2 1 0 3 3 3 3 Leucine-rich repeat TMF_TATA_bd PF12325.3 EGD98987.1 - 0.012 15.3 8.8 0.024 14.3 6.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Mto2_bdg PF12808.2 EGD98987.1 - 0.22 11.6 6.1 0.2 11.7 1.2 2.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GrpE PF01025.14 EGD98987.1 - 0.51 9.8 7.5 5.5 6.4 0.3 2.4 2 0 0 2 2 2 0 GrpE IncA PF04156.9 EGD98987.1 - 3.1 7.3 10.4 8.9 5.8 7.2 1.7 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 EGD98987.1 - 3.1 6.6 11.4 6.2 5.6 7.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_L13e PF01294.13 EGD98988.1 - 1e-66 223.8 3.6 1.4e-66 223.3 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e DUF4404 PF14357.1 EGD98989.1 - 0.0041 17.4 2.7 2.6 8.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4404) Oxidored-like PF09791.4 EGD98990.1 - 4.5e-26 90.0 4.0 9.4e-26 89.0 2.8 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal KAP PF05804.7 EGD98991.1 - 0.0029 15.5 0.0 0.018 12.9 0.0 1.9 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) Glyco_hydro_81 PF03639.8 EGD98991.1 - 0.22 9.4 0.1 0.31 8.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 DPM3 PF08285.6 EGD98992.1 - 1.5e-29 101.6 0.2 1.6e-29 101.5 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Yip1 PF04893.12 EGD98992.1 - 0.042 13.3 2.2 0.054 13.0 1.5 1.0 1 0 0 1 1 1 0 Yip1 domain Pribosyltran PF00156.22 EGD98993.1 - 1.8e-09 37.3 0.1 6e-09 35.6 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SR-25 PF10500.4 EGD98995.1 - 0.0012 18.3 6.0 0.0013 18.2 4.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.5 EGD98995.1 - 0.63 9.8 4.1 0.87 9.3 2.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal YqfQ PF14181.1 EGD98995.1 - 0.65 10.0 3.8 0.3 11.1 1.4 1.5 2 0 0 2 2 2 0 YqfQ-like protein RNase_H2-Ydr279 PF09468.5 EGD98995.1 - 1.7 7.7 8.8 2.2 7.4 6.1 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF788 PF05620.6 EGD98995.1 - 7.4 6.3 5.7 10 5.9 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) HSF_DNA-bind PF00447.12 EGD98996.1 - 2.5e-36 123.9 0.9 5.2e-36 122.9 0.3 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Phage_P2_GpE PF06528.7 EGD98997.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage P2 GpE MSA-2c PF12238.3 EGD98997.1 - 7.2 6.2 8.7 16 5.0 6.0 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF3245 PF11595.3 EGD98998.1 - 1.1e-40 139.2 10.1 1.7e-40 138.7 7.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) DUF4611 PF15387.1 EGD98998.1 - 0.46 10.6 5.1 0.48 10.6 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) ATP-grasp_2 PF08442.5 EGD98999.1 - 6.6e-74 247.6 0.4 1.2e-73 246.8 0.3 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EGD98999.1 - 3.3e-25 88.4 0.7 1.4e-24 86.4 0.2 2.1 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 EGD98999.1 - 6.7e-06 25.4 0.5 1.4e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EGD98999.1 - 0.003 17.1 1.5 0.55 9.7 0.1 2.6 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.1 EGD98999.1 - 0.0041 16.7 0.3 1.1 8.8 0.0 2.5 1 1 1 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_4 PF13535.1 EGD98999.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Spore-coat_CotZ PF10612.4 EGD98999.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Spore coat protein Z adh_short PF00106.20 EGD99000.1 - 2.2e-20 73.2 0.0 3.4e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD99000.1 - 2e-15 57.2 0.0 2.5e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EGD99000.1 - 0.00037 19.7 0.0 0.0057 15.8 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGD99000.1 - 0.0019 18.2 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 EGD99000.1 - 0.046 13.2 0.2 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Beta-lactamase PF00144.19 EGD99001.1 - 2.9e-43 148.1 0.0 3.5e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EGD99001.1 - 0.12 11.5 0.1 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Peptidase_S8 PF00082.17 EGD99002.1 - 3.3e-41 141.2 12.6 4.3e-41 140.9 8.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD99002.1 - 3.3e-19 69.2 0.0 5.7e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 GARS_C PF02843.11 EGD99002.1 - 0.08 13.1 0.9 20 5.4 0.0 2.9 1 1 1 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain DUF4090 PF13319.1 EGD99002.1 - 0.12 12.3 0.3 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4090) SLAC1 PF03595.12 EGD99005.1 - 2.8e-77 259.6 51.2 3.2e-77 259.3 35.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TraP PF07296.6 EGD99005.1 - 0.4 9.6 2.1 0.43 9.5 0.2 1.8 2 0 0 2 2 2 0 TraP protein ABC1 PF03109.11 EGD99006.1 - 1.4e-22 79.9 0.0 4.2e-13 49.2 0.0 2.6 1 1 0 2 2 2 2 ABC1 family APH PF01636.18 EGD99006.1 - 0.044 13.5 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EGD99006.1 - 0.061 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family DUF2238 PF09997.4 EGD99006.1 - 0.15 11.4 0.1 0.68 9.3 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) HA2 PF04408.18 EGD99007.1 - 8.6e-16 57.8 0.0 7.5e-14 51.5 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGD99007.1 - 3.2e-06 26.9 0.0 7.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EGD99007.1 - 0.0065 16.2 0.0 0.047 13.5 0.0 2.5 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EGD99007.1 - 0.021 14.9 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EGD99007.1 - 0.032 13.7 0.1 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Miro PF08477.8 EGD99007.1 - 0.071 13.5 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 EGD99007.1 - 0.082 12.0 0.1 0.19 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SSB PF00436.20 EGD99008.1 - 3.3e-14 52.5 0.0 4.6e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family EFG_II PF14492.1 EGD99008.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Elongation Factor G, domain II STE3 PF02076.10 EGD99009.1 - 1.8e-93 312.7 13.9 2.2e-93 312.4 9.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor Pex24p PF06398.6 EGD99009.1 - 0.021 13.6 2.4 0.045 12.5 1.6 1.6 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin IncA PF04156.9 EGD99010.1 - 0.047 13.2 5.1 0.096 12.2 3.5 1.6 1 1 0 1 1 1 0 IncA protein CCDC-167 PF15188.1 EGD99010.1 - 0.24 11.3 1.4 0.55 10.2 1.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Exo_endo_phos PF03372.18 EGD99011.1 - 7.6e-16 58.7 0.0 1.6e-15 57.7 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EGD99011.1 - 0.11 12.1 0.1 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain DCP1 PF06058.8 EGD99012.1 - 5.9e-16 58.6 0.0 5.3e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 Dcp1-like decapping family DUF1299 PF06975.6 EGD99012.1 - 0.0077 16.0 0.5 0.015 15.1 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1299) DUF2305 PF10230.4 EGD99013.1 - 1.3e-71 241.1 0.0 1.5e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 EGD99013.1 - 2.6e-05 24.0 0.0 0.00012 21.8 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD99013.1 - 0.00063 19.6 0.1 0.00096 19.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGD99013.1 - 0.0058 16.2 0.0 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EGD99013.1 - 0.027 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EGD99013.1 - 0.038 13.6 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) Thioesterase PF00975.15 EGD99013.1 - 0.057 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain DUF3089 PF11288.3 EGD99013.1 - 0.06 12.4 0.1 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) SMK-1 PF04802.10 EGD99014.1 - 1.8e-73 246.1 0.4 3.3e-73 245.3 0.3 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Utp14 PF04615.8 EGD99014.1 - 0.33 9.0 20.9 0.49 8.4 14.5 1.2 1 0 0 1 1 1 0 Utp14 protein DUF1510 PF07423.6 EGD99015.1 - 0.065 12.6 22.1 0.079 12.3 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 EGD99015.1 - 0.2 10.6 27.4 0.22 10.5 19.0 1.0 1 0 0 1 1 1 0 BUD22 DUF262 PF03235.9 EGD99015.1 - 0.45 10.4 4.1 0.46 10.4 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF262 DHHW PF14286.1 EGD99015.1 - 0.6 9.3 5.6 0.7 9.1 3.9 1.0 1 0 0 1 1 1 0 DHHW protein SpoIIIAH PF12685.2 EGD99015.1 - 0.87 9.0 10.4 1.2 8.5 7.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Zip PF02535.17 EGD99015.1 - 1.8 7.4 7.8 2.3 7.1 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.7 EGD99015.1 - 3 5.6 38.3 3.6 5.4 26.5 1.0 1 0 0 1 1 1 0 Nop14-like family PLRV_ORF5 PF01690.12 EGD99015.1 - 4.5 6.3 11.7 4.9 6.1 8.1 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein MIP-T3 PF10243.4 EGD99015.1 - 4.5 5.6 31.6 5.2 5.4 21.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mpp10 PF04006.7 EGD99015.1 - 4.7 5.4 35.8 5.1 5.3 24.8 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF914 PF06027.7 EGD99016.1 - 1.5e-102 342.9 20.1 1.9e-102 342.5 13.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EGD99016.1 - 8.5e-06 25.8 10.2 8.5e-06 25.8 7.1 2.5 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EGD99016.1 - 0.017 15.3 10.4 0.017 15.3 7.2 3.3 2 2 1 3 3 3 0 Multidrug resistance efflux transporter TPT PF03151.11 EGD99016.1 - 0.07 12.7 25.6 0.25 10.9 7.6 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family COQ7 PF03232.8 EGD99018.1 - 0.017 14.5 0.2 0.023 14.1 0.1 1.1 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 CASP_C PF08172.7 EGD99018.1 - 0.032 13.2 1.9 0.035 13.1 1.3 1.1 1 0 0 1 1 1 0 CASP C terminal Prog_receptor PF02161.10 EGD99018.1 - 0.17 10.7 1.0 0.23 10.2 0.7 1.2 1 0 0 1 1 1 0 Progesterone receptor Tom37_C PF11801.3 EGD99018.1 - 0.24 11.2 1.2 0.26 11.1 0.8 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain SAE2 PF08573.5 EGD99018.1 - 0.85 10.3 7.5 1.3 9.8 5.2 1.3 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus TATR PF03430.8 EGD99018.1 - 1.6 7.2 5.3 1.9 7.0 3.7 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Peptidase_S49_N PF08496.5 EGD99018.1 - 1.9 8.2 6.8 3 7.6 4.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OmpH PF03938.9 EGD99018.1 - 2.2 8.2 8.9 2.9 7.8 6.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RNA_GG_bind PF10258.4 EGD99018.1 - 2.3 7.9 7.3 0.92 9.2 0.2 2.7 1 1 2 3 3 3 0 PHAX RNA-binding domain DUF4337 PF14235.1 EGD99018.1 - 2.6 7.8 6.1 3.6 7.4 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) COX16 PF14138.1 EGD99018.1 - 6.4 7.0 7.3 11 6.2 5.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF3007 PF11460.3 EGD99018.1 - 7.4 6.7 5.5 10 6.2 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) PAP_assoc PF03828.14 EGD99020.1 - 8e-18 64.1 0.1 1.9e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EGD99020.1 - 2.1e-06 27.9 0.0 4.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain SE PF08491.5 EGD99021.1 - 2.9e-93 311.6 0.0 3.6e-93 311.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EGD99021.1 - 6.5e-10 38.4 0.2 7.9e-07 28.2 0.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGD99021.1 - 2.8e-09 36.4 0.6 3.8e-08 32.7 0.1 2.3 2 1 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 EGD99021.1 - 1.1e-06 27.7 2.1 4.1e-05 22.6 1.7 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGD99021.1 - 2.5e-05 24.2 0.0 5.6e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD99021.1 - 0.0002 20.5 0.1 0.00026 20.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EGD99021.1 - 0.00035 19.5 0.2 0.00088 18.2 0.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EGD99021.1 - 0.00052 19.9 0.9 0.0011 18.9 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGD99021.1 - 0.00077 18.6 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.15 EGD99021.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EGD99021.1 - 0.0012 19.1 0.2 0.0064 16.8 0.2 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD99021.1 - 0.0013 17.2 0.3 0.0031 16.0 0.2 1.6 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EGD99021.1 - 0.0026 16.7 0.7 0.0052 15.7 0.5 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 EGD99021.1 - 0.008 15.6 0.3 0.029 13.8 0.2 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EGD99021.1 - 0.02 13.5 0.2 0.32 9.5 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 EGD99021.1 - 0.022 14.5 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GDI PF00996.13 EGD99021.1 - 0.077 11.2 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor 3HCDH_N PF02737.13 EGD99021.1 - 0.19 11.3 0.1 0.29 10.7 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PPR_3 PF13812.1 EGD99022.1 - 2.7e-07 30.3 0.5 0.0017 18.5 0.0 5.6 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.15 EGD99022.1 - 4.2e-07 29.4 0.3 0.025 14.5 0.0 5.2 4 0 0 4 4 4 1 PPR repeat PPR_2 PF13041.1 EGD99022.1 - 0.00047 20.0 0.1 0.65 10.0 0.0 4.4 4 0 0 4 4 4 1 PPR repeat family PPR_1 PF12854.2 EGD99022.1 - 0.0016 17.8 0.0 2.5 7.6 0.0 3.4 3 0 0 3 3 3 2 PPR repeat TPR_19 PF14559.1 EGD99022.1 - 0.0025 18.0 0.1 1.4 9.2 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGD99022.1 - 0.027 15.1 0.1 11 6.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3720 PF12517.3 EGD99022.1 - 0.086 13.5 0.3 0.086 13.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) YwhD PF08741.5 EGD99022.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 YwhD family MFS_1 PF07690.11 EGD99023.1 - 9.5e-28 96.9 18.5 5.2e-20 71.4 6.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2269 PF10027.4 EGD99023.1 - 5.9e-05 22.8 3.5 0.00081 19.1 0.2 2.7 2 0 0 2 2 2 1 Predicted integral membrane protein (DUF2269) ATG22 PF11700.3 EGD99023.1 - 0.0086 14.6 24.5 0.23 9.9 4.7 2.6 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like HemY_N PF07219.8 EGD99023.1 - 0.11 12.0 2.1 3 7.4 0.1 3.1 3 0 0 3 3 3 0 HemY protein N-terminus SPC12 PF06645.8 EGD99023.1 - 0.44 10.3 4.7 0.63 9.8 0.7 3.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Ferrochelatase PF00762.14 EGD99024.1 - 2.5e-91 305.9 0.0 2.9e-91 305.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.11 EGD99025.1 - 2.4e-38 131.5 0.0 5e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EGD99025.1 - 1.8e-29 102.7 0.0 2.7e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EGD99025.1 - 5.3e-15 55.7 1.5 1.4e-14 54.4 1.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EGD99025.1 - 9.2e-14 50.5 0.0 2e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 EGD99025.1 - 0.0015 17.9 0.2 0.0015 17.9 0.1 1.9 2 0 0 2 2 2 1 HeH/LEM domain Toprim_3 PF13362.1 EGD99025.1 - 0.12 12.5 0.0 2.9 8.2 0.0 2.7 2 1 1 3 3 3 0 Toprim domain Adap_comp_sub PF00928.16 EGD99026.1 - 3.9e-84 281.8 0.0 5.2e-84 281.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGD99026.1 - 4.3e-05 23.2 0.3 7.3e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Erf4 PF10256.4 EGD99027.1 - 4.2e-34 116.9 0.0 6.1e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Lipase_3 PF01764.20 EGD99028.1 - 0.00034 20.2 0.0 0.00051 19.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.7 EGD99028.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_6 PF12697.2 EGD99028.1 - 0.018 14.8 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.3 EGD99028.1 - 0.028 13.5 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF2974 PF11187.3 EGD99028.1 - 0.059 12.7 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EGD99028.1 - 0.097 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 EGD99028.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) zf-C2H2_jaz PF12171.3 EGD99029.1 - 5.4e-14 51.8 15.4 7.2e-07 29.1 0.4 4.1 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGD99029.1 - 3.8e-13 49.1 15.6 2.8e-07 30.5 0.6 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EGD99029.1 - 1.2e-12 47.3 15.6 0.0055 16.9 0.2 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD99029.1 - 3.6e-11 42.5 15.6 0.0044 17.2 0.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGD99029.1 - 2.6e-09 37.0 14.5 0.0081 16.2 0.4 4.1 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EGD99029.1 - 2.4e-06 27.5 15.0 0.87 9.9 0.0 4.9 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGD99029.1 - 7.2e-06 25.7 11.2 0.015 15.1 0.1 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-DBF PF07535.7 EGD99029.1 - 0.0022 17.6 7.8 0.13 11.9 0.1 3.4 2 1 1 3 3 3 1 DBF zinc finger SprT-like PF10263.4 EGD99029.1 - 0.023 14.3 4.2 0.042 13.4 2.9 1.5 1 0 0 1 1 1 0 SprT-like family C1_1 PF00130.17 EGD99029.1 - 0.04 13.6 5.0 1.3 8.7 0.3 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Di19 PF05605.7 EGD99029.1 - 0.062 13.4 0.2 0.062 13.4 0.2 3.4 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Peptidase_M4 PF01447.13 EGD99029.1 - 0.074 13.1 0.2 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain Zn_Tnp_IS1 PF03811.8 EGD99029.1 - 0.091 12.2 12.0 0.52 9.8 2.9 3.0 3 0 0 3 3 3 0 InsA N-terminal domain zf-DNA_Pol PF08996.5 EGD99029.1 - 0.18 11.1 7.6 0.27 10.5 1.0 2.7 1 1 1 3 3 3 0 DNA Polymerase alpha zinc finger zf-AN1 PF01428.11 EGD99029.1 - 0.29 11.0 15.3 4 7.3 0.3 4.6 5 0 0 5 5 5 0 AN1-like Zinc finger Rpr2 PF04032.11 EGD99029.1 - 0.3 10.9 4.1 4.7 7.1 0.4 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.5 EGD99029.1 - 0.32 10.9 18.5 13 5.8 4.2 4.6 3 1 0 3 3 3 0 Zinc ribbon domain HypA PF01155.14 EGD99029.1 - 0.62 9.7 6.6 35 4.1 4.6 2.3 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_2 PF13639.1 EGD99029.1 - 0.86 9.4 6.0 1.8 8.4 2.1 2.7 2 0 0 2 2 2 0 Ring finger domain C1_4 PF07975.7 EGD99029.1 - 1.3 9.0 13.0 9.7 6.2 1.7 3.1 1 1 2 3 3 3 0 TFIIH C1-like domain zf-3CxxC PF13695.1 EGD99029.1 - 2 8.6 10.5 9.8 6.4 7.3 2.1 1 1 0 1 1 1 0 Zinc-binding domain Cyto_heme_lyase PF01265.12 EGD99030.1 - 1.4e-78 264.1 0.0 1.7e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Pol_alpha_B_N PF08418.5 EGD99030.1 - 6.3 6.2 6.2 9.2 5.7 4.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Fungal_trans_2 PF11951.3 EGD99031.1 - 4.6e-07 28.7 0.1 1.1e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain UQ_con PF00179.21 EGD99032.1 - 6.2e-25 87.2 0.1 8.8e-25 86.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.18 EGD99033.1 - 1.4e-39 136.4 0.1 2e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.12 EGD99034.1 - 1.3e-06 28.0 13.7 0.00011 21.7 5.7 2.3 2 0 0 2 2 2 2 Yip1 domain TFIIA PF03153.8 EGD99035.1 - 1.5 8.6 22.5 1.8 8.3 15.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 EGD99035.1 - 7.1 4.7 12.9 8.2 4.5 8.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4584 PF15223.1 EGD99036.1 - 1.5 7.9 6.8 2.7 7.1 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4584) DUF2796 PF10986.3 EGD99036.1 - 3.1 7.7 9.0 5.1 7.0 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) UFD1 PF03152.9 EGD99037.1 - 7.5e-26 90.3 0.0 2e-23 82.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 HD_2 PF12917.2 EGD99037.1 - 0.2 11.4 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DPPIV_N PF00930.16 EGD99038.1 - 1.3e-110 369.3 6.5 2.1e-110 368.6 4.5 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EGD99038.1 - 1.8e-38 131.8 2.8 3.3e-38 131.0 1.9 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGD99038.1 - 9.1e-06 25.4 0.0 2.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD99038.1 - 0.0023 17.8 0.0 0.0071 16.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S8 PF00082.17 EGD99039.1 - 7.2e-40 136.8 12.5 1e-39 136.3 8.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD99039.1 - 4.5e-14 52.7 0.1 9.1e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 YadA_stalk PF05662.9 EGD99039.1 - 2.9 7.8 8.4 3.2 7.6 0.9 3.0 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin MAPEG PF01124.13 EGD99040.1 - 1.6e-09 37.4 3.7 2.2e-09 37.0 2.5 1.4 1 1 0 1 1 1 1 MAPEG family MARVEL PF01284.18 EGD99041.1 - 7.5e-07 29.0 11.6 1.2e-06 28.4 8.1 1.3 1 1 0 1 1 1 1 Membrane-associating domain CytB6-F_Fe-S PF08802.5 EGD99041.1 - 3.2 7.8 7.2 0.24 11.4 1.1 2.0 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit EmrE PF13536.1 EGD99041.1 - 6.7 6.9 10.0 21 5.3 3.7 2.3 2 1 0 2 2 2 0 Multidrug resistance efflux transporter RNB PF00773.14 EGD99042.1 - 2.7e-56 191.2 0.0 5.6e-55 186.9 0.0 2.2 1 1 0 1 1 1 1 RNB domain DUF3148 PF11347.3 EGD99042.1 - 0.097 12.2 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) CTNNBL PF08216.6 EGD99044.1 - 4.7e-34 116.2 0.3 4.7e-34 116.2 0.2 2.7 4 0 0 4 4 4 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 EGD99044.1 - 0.012 15.8 0.5 0.36 11.1 0.1 3.0 1 1 1 2 2 2 0 HEAT repeats Drf_GBD PF06371.8 EGD99044.1 - 0.07 12.4 0.4 0.71 9.2 0.0 2.7 3 0 0 3 3 3 0 Diaphanous GTPase-binding Domain DUF4200 PF13863.1 EGD99044.1 - 2.6 8.0 7.2 0.93 9.4 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) RNA_pol_Rpb2_6 PF00562.23 EGD99045.1 - 7.3e-124 413.4 0.2 1.7e-123 412.1 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGD99045.1 - 1.4e-60 203.7 0.0 2.2e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGD99045.1 - 2.4e-47 160.8 0.0 4.2e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EGD99045.1 - 2.7e-30 104.4 0.0 5.8e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EGD99045.1 - 3e-24 84.5 0.4 7e-24 83.4 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EGD99045.1 - 6.9e-24 83.5 0.3 1.9e-23 82.1 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EGD99045.1 - 1.3e-22 79.3 1.1 1.8e-22 78.8 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 Nucleopor_Nup85 PF07575.8 EGD99048.1 - 5.9e-17 61.0 2.1 2.7e-10 39.1 0.0 3.4 3 1 0 3 3 3 2 Nup85 Nucleoporin ADH_zinc_N PF00107.21 EGD99050.1 - 1.1e-11 44.3 0.0 1.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD99050.1 - 6.8e-07 29.0 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGD99050.1 - 2.6e-06 28.3 0.0 4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGD99050.1 - 0.0024 17.0 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPR_11 PF13414.1 EGD99051.1 - 8e-25 86.2 19.6 2.3e-06 27.1 0.4 7.3 6 1 2 8 8 7 5 TPR repeat TPR_17 PF13431.1 EGD99051.1 - 2.8e-17 61.4 9.8 0.0076 16.3 0.0 8.4 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGD99051.1 - 1.1e-16 60.9 11.6 0.0038 17.5 0.1 7.7 7 1 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGD99051.1 - 5.3e-12 45.2 11.2 0.32 11.7 0.0 9.0 4 2 5 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGD99051.1 - 5.3e-10 39.6 17.9 0.00012 22.6 0.4 7.6 6 1 3 9 9 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGD99051.1 - 6.8e-10 38.0 16.1 0.014 15.1 0.4 8.3 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGD99051.1 - 7.2e-10 38.0 26.5 0.01 15.6 0.3 9.9 10 0 0 10 10 9 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD99051.1 - 1.7e-08 34.4 17.0 0.002 18.1 1.3 5.8 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGD99051.1 - 1.7e-08 34.2 23.5 0.041 13.8 1.0 7.8 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGD99051.1 - 1.2e-07 31.0 26.4 0.093 12.3 0.4 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGD99051.1 - 0.0001 21.8 14.0 1.8 8.5 0.1 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGD99051.1 - 0.0022 17.7 5.4 0.095 12.5 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EGD99051.1 - 0.014 15.6 0.6 0.5 10.6 0.0 3.1 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation BTAD PF03704.12 EGD99051.1 - 0.015 15.6 0.8 0.094 13.0 0.1 2.4 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_20 PF14561.1 EGD99051.1 - 0.02 14.9 2.9 3.5 7.7 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 EGD99051.1 - 0.096 11.4 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 EGD99051.1 - 0.11 12.4 10.4 0.29 11.1 0.2 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat NARP1 PF12569.3 EGD99051.1 - 0.21 10.3 1.7 11 4.6 0.0 3.0 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 RPN7 PF10602.4 EGD99051.1 - 0.3 10.4 4.3 8.6 5.7 0.1 3.6 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_4 PF07721.9 EGD99051.1 - 7.1 7.3 13.6 0.72 10.4 0.1 4.7 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF3336 PF11815.3 EGD99052.1 - 2.3e-47 160.1 2.0 3.9e-47 159.4 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EGD99052.1 - 5.1e-21 75.5 0.2 1.5e-20 74.0 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase DUF1690 PF07956.6 EGD99052.1 - 0.057 13.4 0.2 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) LRR_4 PF12799.2 EGD99055.1 - 3.3e-05 23.4 0.0 0.0016 17.9 0.0 3.0 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGD99055.1 - 0.035 14.1 0.0 6.3 7.2 0.0 3.5 2 1 1 3 3 3 0 Leucine Rich Repeat SelP_N PF04592.9 EGD99055.1 - 2.8 7.2 41.2 1.3 8.3 4.8 3.5 3 0 0 3 3 3 0 Selenoprotein P, N terminal region Metallophos PF00149.23 EGD99057.1 - 6.7e-45 152.9 0.2 8.2e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arf PF00025.16 EGD99058.1 - 5.8e-64 214.5 0.0 6.4e-64 214.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGD99058.1 - 2.6e-09 36.2 0.1 9.4e-06 24.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EGD99058.1 - 1.6e-08 34.0 0.0 2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EGD99058.1 - 3.7e-07 30.6 0.0 4.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGD99058.1 - 1.5e-06 28.1 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EGD99058.1 - 0.00016 21.1 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGD99058.1 - 0.0012 17.9 0.0 0.0013 17.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGD99058.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EGD99058.1 - 0.11 11.9 0.1 4.7 6.6 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF3435 PF11917.3 EGD99060.1 - 4.4e-67 226.6 1.9 5.2e-40 137.4 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) DUF2457 PF10446.4 EGD99062.1 - 1.1e-141 472.7 37.4 1.1e-141 472.7 25.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) CDC45 PF02724.9 EGD99062.1 - 0.0055 14.7 26.9 0.028 12.4 14.3 2.2 2 0 0 2 2 2 2 CDC45-like protein DUF1510 PF07423.6 EGD99062.1 - 2 7.7 36.1 0.046 13.0 18.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF1206 PF06724.6 EGD99063.1 - 0.026 14.2 0.4 0.045 13.5 0.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Doppel PF11466.3 EGD99063.1 - 2.2 7.9 5.1 12 5.5 1.5 2.1 1 1 1 2 2 2 0 Prion-like protein Doppel CH PF00307.26 EGD99065.1 - 8.6e-06 25.7 0.0 0.046 13.7 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGD99065.1 - 0.0014 18.1 0.0 0.37 10.4 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain IQ PF00612.22 EGD99065.1 - 0.0072 15.8 1.4 0.022 14.3 1.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif HAP2-GCS1 PF10699.4 EGD99065.1 - 0.1 12.5 1.1 0.19 11.6 0.7 1.4 1 0 0 1 1 1 0 Male gamete fusion factor Ank_2 PF12796.2 EGD99066.1 - 2.4e-41 139.9 5.5 1.5e-12 47.6 0.2 4.7 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EGD99066.1 - 9.3e-31 104.0 0.0 9.1e-06 25.2 0.0 8.5 8 2 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EGD99066.1 - 4.1e-27 94.0 3.3 7.2e-05 23.1 0.1 6.3 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD99066.1 - 1.9e-23 81.9 5.2 7e-09 35.6 0.5 5.5 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD99066.1 - 5.1e-18 63.3 1.5 0.023 14.8 0.0 8.4 9 1 0 9 9 9 4 Ankyrin repeat Vezatin PF12632.2 EGD99067.1 - 1.2e-54 185.0 0.4 2.5e-54 184.0 0.2 1.5 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Polysacc_synt_C PF14667.1 EGD99067.1 - 0.017 14.9 5.9 0.027 14.2 4.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain MatE PF01554.13 EGD99067.1 - 0.018 14.6 0.1 4.3 6.9 0.1 2.2 1 1 1 2 2 2 0 MatE PCNA_C PF02747.10 EGD99068.1 - 8.3e-53 177.6 0.0 3.4e-52 175.7 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 EGD99068.1 - 9.8e-46 154.3 3.8 1.8e-45 153.4 2.6 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 EGD99068.1 - 2.6e-07 30.0 0.0 3.3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EGD99068.1 - 2.4e-05 23.2 0.2 0.00024 20.0 0.0 1.9 1 1 1 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 EGD99068.1 - 0.064 12.1 0.1 2.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Hus1-like protein LXG PF04740.7 EGD99068.1 - 0.13 12.0 0.1 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily Fungal_trans_2 PF11951.3 EGD99069.1 - 6.9e-19 67.7 0.2 2.9e-14 52.4 0.8 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD99069.1 - 3.7e-07 29.9 11.9 7.9e-07 28.8 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dicty_REP PF05086.7 EGD99069.1 - 0.58 7.8 0.7 0.82 7.3 0.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Asp_protease PF09668.5 EGD99070.1 - 4.3e-61 203.9 0.2 7.1e-61 203.2 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EGD99070.1 - 2.6e-11 43.8 0.1 1.1e-10 41.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.18 EGD99070.1 - 7.8e-11 41.2 0.0 1.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EGD99070.1 - 1e-07 31.5 0.0 2.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 EGD99070.1 - 4.3e-06 26.7 0.0 7.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGD99070.1 - 4.7e-06 26.3 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Rad60-SLD PF11976.3 EGD99070.1 - 0.00041 19.9 0.0 0.001 18.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.15 EGD99070.1 - 0.00053 19.8 0.0 0.0015 18.3 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 EGD99070.1 - 0.0029 17.0 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UN_NPL4 PF11543.3 EGD99070.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.1 EGD99070.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Acetyltransf_1 PF00583.19 EGD99071.1 - 2.4e-08 33.9 0.0 3.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD99071.1 - 1.2e-07 31.8 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD99071.1 - 0.00024 20.7 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EGD99071.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD99071.1 - 0.023 14.8 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nucleoplasmin PF03066.10 EGD99071.1 - 0.031 13.8 0.7 0.057 12.9 0.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin Acetyltransf_8 PF13523.1 EGD99071.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Osteopontin PF00865.13 EGD99071.1 - 1.2 8.3 12.1 1.8 7.7 8.4 1.2 1 0 0 1 1 1 0 Osteopontin PBP1_TM PF14812.1 EGD99071.1 - 1.3 9.3 5.6 2.7 8.3 3.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 EGD99071.1 - 3.4 6.3 12.6 5 5.7 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOGCT PF08155.6 EGD99072.1 - 6.8e-30 102.5 1.1 1.4e-29 101.4 0.8 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EGD99072.1 - 1.2e-26 92.2 0.6 3.1e-26 90.9 0.4 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EGD99072.1 - 1e-14 54.4 0.0 2.3e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGD99072.1 - 8.7e-08 31.5 0.0 3.2e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EGD99072.1 - 2.9e-05 24.5 0.0 8.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EGD99072.1 - 0.0055 16.5 0.0 2.2 8.0 0.0 2.7 1 1 1 2 2 2 2 Dynamin family DUF506 PF04720.7 EGD99072.1 - 0.036 13.6 3.1 0.41 10.2 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF506) AAA_16 PF13191.1 EGD99072.1 - 0.079 12.9 1.0 1.5 8.7 0.0 3.2 3 1 1 4 4 4 0 AAA ATPase domain E1_DerP2_DerF2 PF02221.10 EGD99073.1 - 7.1e-25 87.8 0.1 8.4e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EGD99073.1 - 2.8e-05 24.1 0.0 0.00016 21.7 0.0 1.9 1 1 0 1 1 1 1 ML-like domain Glyco_hydro_61 PF03443.9 EGD99073.1 - 0.073 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 ATP-synt_F PF01990.12 EGD99074.1 - 4.1e-31 107.2 0.1 4.7e-31 107.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 EGD99074.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 DUF2418 PF10332.4 EGD99075.1 - 9.1e-35 118.9 0.3 1.5e-34 118.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) NADH-u_ox-rdase PF10785.4 EGD99075.1 - 0.13 12.5 0.1 12 6.2 0.0 3.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit MTHFR PF02219.12 EGD99077.1 - 6.5e-116 386.4 0.0 9.5e-116 385.8 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1804 PF08822.6 EGD99077.1 - 0.042 13.5 0.2 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) DUF3734 PF12536.3 EGD99078.1 - 0.094 12.8 0.3 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 Patatin phospholipase Tom37_C PF11801.3 EGD99078.1 - 0.17 11.7 1.7 0.21 11.4 1.2 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain PBP1_TM PF14812.1 EGD99078.1 - 0.39 11.0 8.0 0.6 10.4 4.8 1.8 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3959 PF13105.1 EGD99078.1 - 1.8 7.8 7.7 2.2 7.5 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Pribosyltran PF00156.22 EGD99079.1 - 1.8e-14 53.4 0.2 3.4e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GTP_cyclohydro2 PF00925.15 EGD99079.1 - 0.059 12.6 0.0 0.57 9.4 0.0 2.0 2 0 0 2 2 2 0 GTP cyclohydrolase II Aconitase PF00330.15 EGD99080.1 - 4.4e-184 612.3 0.0 5.4e-184 612.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGD99080.1 - 1.4e-44 151.3 0.0 2.6e-44 150.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Glycos_transf_4 PF00953.16 EGD99081.1 - 1.2e-32 112.9 10.7 1.2e-32 112.9 7.4 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 4 WD40 PF00400.27 EGD99082.1 - 1.2e-20 72.5 5.6 3.4e-06 26.7 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat SWIRM PF04433.12 EGD99084.1 - 5.8e-17 61.5 0.0 1.5e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 EGD99084.1 - 2.4e-09 36.5 4.4 4.3e-09 35.7 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EGD99084.1 - 4.1e-08 33.1 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain PG_binding_1 PF01471.13 EGD99084.1 - 0.0091 15.9 0.0 0.034 14.1 0.0 2.0 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Pkinase PF00069.20 EGD99085.1 - 3.6e-70 236.0 0.0 4.8e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD99085.1 - 6.1e-33 113.9 0.0 8.5e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGD99085.1 - 1.1e-08 35.4 0.1 1.1e-08 35.4 0.1 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGD99085.1 - 0.00058 18.9 0.0 0.00091 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Coatomer_WDAD PF04053.9 EGD99086.1 - 9.7e-170 565.1 0.0 2.3e-169 563.9 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EGD99086.1 - 1.3e-46 154.8 6.9 2.2e-10 40.0 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EGD99086.1 - 0.0032 15.6 4.4 0.08 11.0 0.1 3.7 3 1 2 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EGD99086.1 - 0.0058 16.3 0.0 3.6 7.4 0.0 3.3 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region ETC_C1_NDUFA5 PF04716.9 EGD99087.1 - 7e-23 79.9 1.3 2.4e-22 78.1 0.1 2.4 2 0 0 2 2 2 1 ETC complex I subunit conserved region DUF1192 PF06698.6 EGD99087.1 - 0.08 12.7 0.5 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Thioredoxin PF00085.15 EGD99088.1 - 2.9e-43 145.7 0.0 3.7e-25 87.6 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EGD99088.1 - 4.9e-15 55.7 0.0 4.5e-06 26.5 0.0 4.2 3 1 1 4 4 4 4 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGD99088.1 - 2.6e-06 27.4 0.2 0.0051 16.9 0.0 3.7 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGD99088.1 - 5.8e-06 26.4 2.3 0.046 13.9 0.1 4.6 3 2 0 3 3 3 2 Thioredoxin-like domain HyaE PF07449.6 EGD99088.1 - 0.00031 20.6 0.0 0.38 10.6 0.0 2.8 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 EGD99088.1 - 0.00039 20.3 0.7 0.0072 16.3 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EGD99088.1 - 0.0063 16.2 0.0 0.16 11.8 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain DAO PF01266.19 EGD99089.1 - 3.7e-43 147.8 0.2 4.9e-43 147.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 EGD99089.1 - 0.005 16.6 0.0 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 ThiF family NAD_binding_8 PF13450.1 EGD99089.1 - 0.0094 15.9 0.0 0.034 14.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGD99089.1 - 0.026 14.3 0.1 0.077 12.7 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGD99089.1 - 0.04 13.8 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGD99089.1 - 0.043 12.6 1.0 0.073 11.9 0.7 1.4 1 1 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EGD99089.1 - 0.32 10.7 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TadE PF07811.7 EGD99089.1 - 1 9.2 4.8 0.28 11.0 0.6 2.0 2 0 0 2 2 2 0 TadE-like protein MFS_1 PF07690.11 EGD99090.1 - 1.5e-27 96.2 28.3 1.5e-27 96.2 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HNH_2 PF13391.1 EGD99091.1 - 9.9e-08 31.6 0.0 2.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease CRF PF00473.12 EGD99091.1 - 0.13 12.3 0.4 0.61 10.2 0.1 2.2 2 0 0 2 2 2 0 Corticotropin-releasing factor family Na_Ca_ex PF01699.19 EGD99092.1 - 3.4e-43 146.5 36.7 1e-22 80.2 7.2 2.8 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF3810 PF12725.2 EGD99092.1 - 0.13 11.1 1.0 0.23 10.3 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DUF1352 PF07086.7 EGD99092.1 - 1.5 8.4 5.2 0.67 9.5 1.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1352) Ribosomal_S7 PF00177.16 EGD99093.1 - 7e-29 100.3 0.0 1.3e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF1013 PF06242.6 EGD99093.1 - 0.079 12.9 0.5 0.37 10.7 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1013) Peptidase_S28 PF05577.7 EGD99095.1 - 9.5e-53 179.3 0.0 5.2e-52 176.8 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EGD99095.1 - 0.032 13.4 0.1 0.077 12.1 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family SPX PF03105.14 EGD99096.1 - 1.4e-46 159.5 0.2 3.1e-46 158.3 0.1 1.6 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EGD99096.1 - 1.5e-27 96.6 43.0 2.3e-27 96.0 29.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EGD99096.1 - 2.6e-11 42.6 24.9 2.6e-11 42.6 17.3 2.5 1 1 2 3 3 3 3 Citrate transporter DUF3290 PF11694.3 EGD99096.1 - 0.23 11.2 0.0 0.23 11.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) Ribonuclease_T2 PF00445.13 EGD99097.1 - 1.6e-44 151.8 0.8 1.6e-44 151.8 0.5 1.4 2 0 0 2 2 2 1 Ribonuclease T2 family DUF1792 PF08759.6 EGD99097.1 - 0.0019 17.8 0.4 0.0028 17.2 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1792) Tissue_fac PF01108.12 EGD99097.1 - 0.41 10.4 4.9 1.4 8.6 0.1 2.4 1 1 1 2 2 2 0 Tissue factor Ribosomal_S8e PF01201.17 EGD99098.1 - 2.1e-48 163.8 1.8 2.4e-48 163.6 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DUF4557 PF15101.1 EGD99099.1 - 0.63 9.8 4.2 0.97 9.2 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) NmrA PF05368.8 EGD99100.1 - 2.6e-16 59.5 0.0 3.4e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.20 EGD99100.1 - 0.065 13.1 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Glyco_hydro_20 PF00728.17 EGD99101.1 - 6.1e-97 324.9 0.0 7.5e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EGD99101.1 - 4.3e-20 72.6 0.0 2.4e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EGD99101.1 - 5.8e-06 26.8 0.0 1.2e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF2664 PF10867.3 EGD99101.1 - 0.14 12.8 0.2 6.1 7.5 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) DOCK-C2 PF14429.1 EGD99102.1 - 3e-28 98.6 0.0 1.2e-27 96.7 0.0 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EGD99102.1 - 2.6e-14 52.9 0.8 5.3e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 Dedicator of cytokinesis SH3_1 PF00018.23 EGD99102.1 - 2.4e-05 23.6 0.0 6.1e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD99102.1 - 0.00053 19.5 0.1 0.0047 16.4 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EGD99102.1 - 0.056 12.9 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Sec3-PIP2_bind PF15277.1 EGD99103.1 - 5.3e-31 106.3 0.2 1e-30 105.3 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.4 EGD99103.1 - 4.1e-25 88.0 0.4 7.3e-25 87.2 0.3 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 Tir_receptor_C PF07489.6 EGD99103.1 - 0.3 10.7 10.6 0.59 9.8 7.4 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Mucin PF01456.12 EGD99103.1 - 0.64 9.7 18.4 2.1 8.1 12.8 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 EGD99103.1 - 1.1 9.0 14.6 2.5 7.8 10.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 EGD99103.1 - 3.1 5.6 14.6 4.5 5.1 10.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 EGD99103.1 - 4.4 4.9 9.3 6.2 4.4 6.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SRP40_C PF05022.7 EGD99104.1 - 1.7e-22 79.6 0.1 4.3e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 SRP40, C-terminal domain F-box-like PF12937.2 EGD99105.1 - 7.7e-07 28.7 0.6 2e-06 27.4 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD99105.1 - 8.9e-06 25.2 0.1 2.2e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain Lactonase PF10282.4 EGD99105.1 - 0.037 13.0 0.0 0.083 11.9 0.0 1.4 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller HNH_2 PF13391.1 EGD99106.1 - 2.1e-11 43.4 0.0 5.3e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease p450 PF00067.17 EGD99107.1 - 6e-48 163.5 0.0 6.3e-47 160.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF1903 PF08991.5 EGD99108.1 - 0.079 13.1 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) DUF1992 PF09350.5 EGD99109.1 - 4.3e-18 64.9 0.2 1.3e-17 63.3 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) MTBP_mid PF14919.1 EGD99109.1 - 0.064 11.9 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 MDM2-binding Gate PF07670.9 EGD99110.1 - 0.052 13.4 0.2 0.58 10.0 0.2 2.3 1 1 0 1 1 1 0 Nucleoside recognition Methyltransf_25 PF13649.1 EGD99112.1 - 0.0013 19.0 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF2610 PF11020.3 EGD99112.1 - 0.1 12.3 0.0 6 6.7 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2610) Acetyltransf_8 PF13523.1 EGD99115.1 - 3.6e-32 111.3 0.0 5.2e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_C28 PF05408.6 EGD99115.1 - 0.18 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase ATP_bind_3 PF01171.15 EGD99116.1 - 1.4e-11 44.2 0.0 2.3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EGD99116.1 - 0.0023 18.2 0.0 0.0063 16.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 EGD99116.1 - 0.012 15.0 1.2 0.012 15.0 0.9 2.4 3 0 0 3 3 3 0 RecR protein zf-UBR PF02207.15 EGD99116.1 - 0.098 12.3 6.9 0.38 10.4 0.7 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) SBF PF01758.11 EGD99117.1 - 2.3e-50 170.6 13.1 2.3e-50 170.6 9.1 2.3 2 1 0 2 2 2 1 Sodium Bile acid symporter family Cyclin_N PF00134.18 EGD99120.1 - 1e-10 41.2 0.0 2.8e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 EGD99120.1 - 1.6e-08 35.1 0.0 3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin AKAP2_C PF15304.1 EGD99120.1 - 6.1 6.3 12.7 0.065 12.8 2.0 2.0 1 1 0 2 2 2 0 A-kinase anchor protein 2 C-terminus DUF1777 PF08648.7 EGD99120.1 - 7.7 6.2 15.6 1.4e+02 2.0 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) Complex1_LYR_2 PF13233.1 EGD99121.1 - 1.1e-20 73.9 0.2 1.4e-20 73.7 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF3071 PF11268.3 EGD99121.1 - 0.031 14.0 1.0 0.033 13.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) zf-HIT PF04438.11 EGD99122.1 - 1.4e-09 37.4 7.9 2e-09 36.9 5.5 1.3 1 0 0 1 1 1 1 HIT zinc finger PRK PF00485.13 EGD99122.1 - 0.15 11.5 0.1 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family zf-B_box PF00643.19 EGD99122.1 - 0.27 11.1 7.7 0.48 10.3 5.3 1.3 1 0 0 1 1 1 0 B-box zinc finger API5 PF05918.6 EGD99122.1 - 1.5 7.2 5.1 2 6.8 3.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Tnp_zf-ribbon_2 PF13842.1 EGD99122.1 - 9.7 6.6 11.6 18 5.8 8.0 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon RasGEF PF00617.14 EGD99123.1 - 2.3e-45 154.6 0.1 3.8e-45 153.9 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGD99123.1 - 3.1e-13 49.7 0.0 8.2e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EGD99123.1 - 1.3e-09 38.5 0.0 2.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EGD99123.1 - 0.0056 16.0 0.0 0.018 14.4 0.0 1.8 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.1 EGD99123.1 - 0.016 15.1 0.4 0.38 10.7 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.12 EGD99123.1 - 0.026 14.0 0.2 1 8.8 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EGD99123.1 - 0.069 12.5 0.3 3.1 7.1 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain Nfu_N PF08712.6 EGD99124.1 - 2.4e-25 87.9 0.0 7.1e-25 86.4 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EGD99124.1 - 8.1e-23 79.9 0.1 2e-22 78.7 0.0 1.7 2 0 0 2 2 2 1 NifU-like domain PSP1 PF04468.7 EGD99125.1 - 5.1e-31 106.5 1.3 8e-31 105.8 0.9 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rotavirus_VP3 PF06929.6 EGD99125.1 - 0.29 8.9 0.4 0.44 8.3 0.3 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein Tis11B_N PF04553.7 EGD99125.1 - 2.2 8.5 6.6 13 6.0 0.3 2.6 2 0 0 2 2 2 0 Tis11B like protein, N terminus Cornichon PF03311.9 EGD99126.1 - 4.5e-54 182.0 11.8 5.1e-54 181.8 8.2 1.0 1 0 0 1 1 1 1 Cornichon protein MFS_1 PF07690.11 EGD99127.1 - 2.7e-19 69.0 35.1 2.7e-19 69.0 24.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EGD99127.1 - 9.7e-08 30.5 2.1 2e-07 29.5 1.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector TerC PF03741.11 EGD99127.1 - 0.0012 18.3 0.2 0.0012 18.3 0.1 2.6 2 1 0 2 2 2 1 Integral membrane protein TerC family ABC2_membrane PF01061.19 EGD99128.1 - 3.4e-37 127.6 18.8 5.8e-37 126.9 13.1 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGD99128.1 - 5.7e-27 94.6 0.1 1.1e-26 93.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGD99128.1 - 9.9e-10 38.8 0.1 7.7e-09 35.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EGD99128.1 - 4.7e-09 35.7 20.0 1.6e-08 33.9 13.9 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein hEGF PF12661.2 EGD99128.1 - 4.3e-05 23.3 22.5 0.01 15.8 1.9 3.9 3 0 0 3 3 3 2 Human growth factor-like EGF AAA_25 PF13481.1 EGD99128.1 - 6.6e-05 22.4 0.0 0.01 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain EGF_2 PF07974.8 EGD99128.1 - 0.00038 20.5 11.4 0.00038 20.5 7.9 3.9 4 0 0 4 4 3 2 EGF-like domain AAA_15 PF13175.1 EGD99128.1 - 0.0011 18.1 0.0 0.64 8.9 0.0 2.3 1 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EGD99128.1 - 0.0021 17.5 0.1 0.0051 16.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 EGD99128.1 - 0.0042 16.6 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 EGD99128.1 - 0.0076 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGD99128.1 - 0.0085 16.2 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EGD99128.1 - 0.017 15.4 0.1 0.041 14.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGD99128.1 - 0.02 15.7 0.0 0.041 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EGD99128.1 - 0.023 14.1 0.1 0.06 12.7 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 EGD99128.1 - 0.026 13.7 0.1 0.14 11.4 0.1 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF1212 PF06738.7 EGD99128.1 - 0.033 13.6 1.3 0.079 12.4 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) AAA_33 PF13671.1 EGD99128.1 - 0.038 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGD99128.1 - 0.039 13.9 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EGD99128.1 - 0.039 14.2 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGD99128.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glycophorin_A PF01102.13 EGD99128.1 - 0.16 11.7 1.4 0.39 10.4 0.0 2.5 2 0 0 2 2 1 0 Glycophorin A Aminotran_1_2 PF00155.16 EGD99129.1 - 8.3e-43 146.7 0.0 1e-42 146.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD99129.1 - 3.9e-08 32.7 0.0 7.7e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGD99129.1 - 9.7e-07 27.8 0.0 1.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGD99129.1 - 6e-06 24.7 0.0 9.1e-06 24.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGD99129.1 - 1.1e-05 24.6 0.0 2.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 EGD99129.1 - 0.17 10.5 0.0 0.5 8.9 0.0 1.7 1 1 0 2 2 2 0 Allinase Peptidase_M36 PF02128.10 EGD99130.1 - 4.9e-160 532.4 11.7 7.1e-160 531.9 8.1 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGD99130.1 - 1.4e-11 43.6 2.9 2.7e-11 42.7 2.0 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif AMP-binding PF00501.23 EGD99131.1 - 2.9e-71 240.0 0.0 4.4e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD99131.1 - 4.4e-11 43.5 0.1 9.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lyase_1 PF00206.15 EGD99132.1 - 2.8e-85 286.2 0.0 4.7e-85 285.5 0.0 1.4 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EGD99132.1 - 1.7e-26 92.0 0.0 4.7e-26 90.6 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Sulfatase PF00884.18 EGD99133.1 - 3.9e-22 78.8 0.2 7.6e-22 77.8 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EGD99133.1 - 1e-06 28.3 0.0 2.4e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EGD99133.1 - 0.0045 15.4 0.0 0.007 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) JmjC PF02373.17 EGD99134.1 - 7e-06 26.2 0.0 1.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ZZ PF00569.12 EGD99134.1 - 1.5e-05 24.3 8.7 1.5e-05 24.3 6.0 2.6 2 1 0 2 2 2 1 Zinc finger, ZZ type Baculo_IE-1 PF05290.6 EGD99134.1 - 0.051 13.3 7.7 0.032 13.9 1.1 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Cupin_2 PF07883.6 EGD99134.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain zf-4CXXC_R1 PF10497.4 EGD99134.1 - 9 6.4 14.9 0.035 14.2 2.7 2.3 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Polyketide_cyc PF03364.15 EGD99136.1 - 9.1e-20 70.9 0.0 1.7e-19 70.0 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Sod_Fe_C PF02777.13 EGD99137.1 - 6e-17 61.4 0.0 2.1e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Orthoreo_P10 PF07204.6 EGD99138.1 - 0.046 13.4 0.2 0.61 9.8 0.0 2.5 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 PIG-S PF10510.4 EGD99139.1 - 3.4e-151 504.4 9.3 2.8e-137 458.5 1.9 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein PQQ_2 PF13360.1 EGD99140.1 - 7e-07 28.9 0.5 0.0011 18.5 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain WD40 PF00400.27 EGD99140.1 - 0.0019 18.0 4.5 0.57 10.1 0.1 4.7 4 2 0 4 4 4 1 WD domain, G-beta repeat TLP-20 PF06088.6 EGD99140.1 - 0.013 15.1 2.2 0.02 14.5 1.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nucleoplasmin PF03066.10 EGD99140.1 - 0.013 14.9 2.0 0.023 14.2 1.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin Tom37_C PF11801.3 EGD99140.1 - 0.066 13.0 0.8 0.1 12.4 0.6 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain CDC45 PF02724.9 EGD99140.1 - 2 6.3 7.7 2.7 5.9 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Fe-ADH PF00465.14 EGD99142.1 - 3.2e-67 226.7 2.9 3.6e-67 226.5 2.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGD99142.1 - 3.5e-12 46.1 1.0 5e-12 45.6 0.7 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Diphthamide_syn PF01866.12 EGD99143.1 - 7e-52 176.5 0.0 2.4e-51 174.8 0.0 1.8 2 1 0 2 2 2 1 Putative diphthamide synthesis protein DUF1923 PF09083.5 EGD99143.1 - 0.045 13.2 0.1 13 5.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) Methyltransf_12 PF08242.7 EGD99146.1 - 4.9e-15 55.8 0.0 2.1e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD99146.1 - 9.3e-12 45.2 0.0 2.1e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD99146.1 - 6.1e-10 39.0 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD99146.1 - 5.2e-09 35.8 0.0 8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD99146.1 - 1.5e-08 35.1 0.0 4.3e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD99146.1 - 8.9e-08 32.4 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD99146.1 - 1.9e-07 31.1 0.1 7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD99146.1 - 3.6e-05 23.0 0.0 5.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 EGD99146.1 - 0.00017 20.6 0.0 0.02 13.9 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.9 EGD99146.1 - 0.00099 18.5 0.1 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EGD99146.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 EGD99146.1 - 0.0024 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.1 EGD99146.1 - 0.0076 17.0 0.0 0.018 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.3 EGD99146.1 - 0.027 13.1 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) FmrO PF07091.6 EGD99146.1 - 0.06 12.3 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) CMAS PF02353.15 EGD99146.1 - 0.071 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 EGD99146.1 - 0.095 12.3 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase Sugar_tr PF00083.19 EGD99147.1 - 2e-120 402.4 21.4 3.5e-120 401.6 14.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD99147.1 - 8.3e-24 83.9 46.0 6e-15 54.8 10.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily HlyIII PF03006.15 EGD99148.1 - 3.2e-58 196.7 23.4 3.9e-58 196.4 16.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related GlnD_UR_UTase PF08335.6 EGD99148.1 - 0.32 10.8 5.2 0.52 10.1 0.4 2.2 1 1 1 2 2 2 0 GlnD PII-uridylyltransferase Planc_extracel PF07595.7 EGD99148.1 - 0.5 10.1 8.1 3 7.6 0.1 2.8 2 0 0 2 2 2 0 Planctomycete extracellular FimP PF09766.4 EGD99149.1 - 5.5e-28 98.0 10.8 7e-28 97.7 7.5 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 EGD99149.1 - 3.5e-05 23.7 12.9 0.0045 16.9 0.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) DUF948 PF06103.6 EGD99149.1 - 0.016 15.0 3.5 4.7 7.1 0.0 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) K-box PF01486.12 EGD99149.1 - 0.016 14.9 0.7 0.016 14.9 0.5 3.2 2 2 1 3 3 3 0 K-box region Flagellin_N PF00669.15 EGD99149.1 - 0.057 13.2 0.9 0.057 13.2 0.6 2.1 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region IncA PF04156.9 EGD99149.1 - 0.22 11.1 14.8 0.81 9.2 1.1 2.1 2 0 0 2 2 2 0 IncA protein RNase_E_G PF10150.4 EGD99149.1 - 0.49 9.5 4.9 0.18 11.0 1.3 1.6 2 0 0 2 2 2 0 Ribonuclease E/G family DUF972 PF06156.8 EGD99149.1 - 0.71 10.2 10.1 0.89 9.9 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF349 PF03993.7 EGD99149.1 - 0.76 9.9 9.5 0.13 12.4 3.5 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) BLOC1_2 PF10046.4 EGD99149.1 - 1.7 8.8 7.0 1.4 9.1 0.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DIE2_ALG10 PF04922.7 EGD99150.1 - 8.9e-63 212.5 17.3 2.8e-32 112.2 1.2 3.1 2 2 0 2 2 2 2 DIE2/ALG10 family Sld5 PF05916.6 EGD99151.1 - 9.1e-27 93.4 0.0 1.6e-26 92.7 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein CUE PF02845.11 EGD99152.1 - 1.6e-10 40.2 0.0 2.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain SMC_N PF02463.14 EGD99153.1 - 3.1e-70 235.8 0.0 1.3e-69 233.7 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGD99153.1 - 4.4e-22 78.2 1.2 4.7e-21 74.9 0.2 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGD99153.1 - 9.2e-13 48.8 7.3 1.5e-05 25.1 0.0 3.7 3 0 0 3 3 3 2 AAA domain MscS_porin PF12795.2 EGD99153.1 - 0.00011 21.6 18.6 0.00011 21.6 12.9 5.6 3 2 2 6 6 6 2 Mechanosensitive ion channel porin domain AAA_29 PF13555.1 EGD99153.1 - 0.00081 18.8 0.1 0.002 17.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 EGD99153.1 - 0.0029 16.8 8.1 0.0029 16.8 5.6 7.1 3 2 3 6 6 6 2 Growth-arrest specific micro-tubule binding ABC_tran PF00005.22 EGD99153.1 - 0.058 13.6 0.1 0.058 13.6 0.0 5.4 4 2 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 EGD99153.1 - 0.2 10.8 33.1 0.54 9.3 1.4 5.7 3 2 5 8 8 8 0 Reovirus sigma C capsid protein GDI PF00996.13 EGD99154.1 - 1e-181 604.0 0.0 1.3e-181 603.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EGD99154.1 - 0.052 13.5 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.8 EGD99155.1 - 9.2e-21 73.5 0.2 1.5e-20 72.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) NOT2_3_5 PF04153.13 EGD99156.1 - 3.3e-33 114.4 0.1 3.3e-33 114.4 0.1 2.4 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family 4HBT PF03061.17 EGD99157.1 - 1.2e-10 41.4 0.1 1.7e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EGD99157.1 - 4.7e-05 23.2 0.1 7.9e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily CDC73 PF05179.9 EGD99158.1 - 7.4e-40 137.0 0.4 6.6e-39 133.9 0.4 2.4 2 1 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family X PF00739.14 EGD99158.1 - 0.22 11.4 0.1 0.22 11.4 0.0 2.5 3 1 0 3 3 3 0 Trans-activation protein X AA_permease PF00324.16 EGD99159.1 - 7.3e-75 252.1 24.6 8.2e-75 251.9 17.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD99159.1 - 1.5e-14 53.3 23.6 1.7e-14 53.1 16.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EGD99159.1 - 0.0056 16.4 3.1 0.0056 16.4 2.2 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1772) Abhydrolase_6 PF12697.2 EGD99160.1 - 4.9e-18 65.8 0.6 2.5e-17 63.5 0.4 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD99160.1 - 8.3e-08 32.1 0.0 3.5e-06 26.8 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD99160.1 - 9.6e-07 28.5 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tmemb_cc2 PF10267.4 EGD99160.1 - 0.088 11.3 3.8 0.2 10.1 2.7 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Glutaredoxin PF00462.19 EGD99161.1 - 3.2e-12 46.2 0.0 4.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Ribosomal_L6 PF00347.18 EGD99162.1 - 1.2e-22 80.1 6.6 1e-10 41.9 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 RXT2_N PF08595.6 EGD99163.1 - 8.7e-30 103.4 0.1 8.7e-30 103.4 0.1 3.0 3 1 1 4 4 4 1 RXT2-like, N-terminal PEMT PF04191.8 EGD99164.1 - 4.6e-33 113.5 2.4 1.1e-32 112.2 1.0 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF924 PF06041.6 EGD99165.1 - 1.5e-47 161.7 0.1 1.8e-47 161.5 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) SUR7 PF06687.7 EGD99166.1 - 6.3e-40 137.0 8.4 9.3e-40 136.4 5.8 1.3 1 0 0 1 1 1 1 SUR7/PalI family Acetyltransf_1 PF00583.19 EGD99168.1 - 4.4e-14 52.2 0.0 6.5e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGD99168.1 - 3.2e-07 29.9 0.0 5.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGD99168.1 - 0.00027 21.0 0.0 0.00041 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD99168.1 - 0.0034 17.2 0.1 0.0062 16.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGD99168.1 - 0.0079 16.3 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SR-25 PF10500.4 EGD99169.1 - 2.9e-05 23.6 16.1 2.9e-05 23.6 11.2 2.9 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein TelA PF05816.6 EGD99169.1 - 0.0005 18.8 4.5 0.0005 18.8 3.1 2.1 3 0 0 3 3 3 1 Toxic anion resistance protein (TelA) Sigma70_ner PF04546.8 EGD99169.1 - 0.0043 16.6 1.2 0.0043 16.6 0.9 3.1 3 0 0 3 3 3 1 Sigma-70, non-essential region DUF4646 PF15496.1 EGD99169.1 - 0.019 15.0 1.6 0.14 12.2 1.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) Macoilin PF09726.4 EGD99169.1 - 0.29 9.3 33.3 1 7.5 23.1 1.8 1 1 0 1 1 1 0 Transmembrane protein Sipho_Gp157 PF05565.6 EGD99169.1 - 0.42 10.1 13.2 0.15 11.6 6.4 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 V_ATPase_I PF01496.14 EGD99169.1 - 2.8 5.6 4.3 5.8 4.6 3.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Golgin_A5 PF09787.4 EGD99169.1 - 5.4 5.4 31.6 0.032 12.7 7.2 3.0 3 0 0 3 3 3 0 Golgin subfamily A member 5 OmpH PF03938.9 EGD99169.1 - 6.2 6.7 36.6 1.8 8.5 10.9 3.5 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) Plasmodium_Vir PF05795.6 EGD99169.1 - 6.4 5.8 10.8 13 4.8 0.0 2.8 3 0 0 3 3 3 0 Plasmodium vivax Vir protein Pkinase PF00069.20 EGD99170.1 - 1e-09 37.9 0.0 1.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EGD99170.1 - 1.6e-08 33.9 2.2 0.1 12.6 0.0 5.4 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EGD99170.1 - 4.2e-06 27.0 0.2 0.16 12.5 0.0 3.7 3 0 0 3 3 3 2 HEAT-like repeat Pkinase_Tyr PF07714.12 EGD99170.1 - 9.4e-06 24.8 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EGD99170.1 - 0.00061 20.0 0.2 0.3 11.4 0.1 4.1 2 1 1 4 4 4 1 HEAT repeats Kinase-like PF14531.1 EGD99170.1 - 0.026 13.4 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Cnd1 PF12717.2 EGD99170.1 - 0.043 13.6 0.0 0.21 11.4 0.0 2.0 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EGD99170.1 - 0.056 11.7 0.0 1.6 6.9 0.0 2.0 1 1 2 3 3 3 0 Adaptin N terminal region CoA_trans PF01144.18 EGD99170.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase Ribonuclease PF00545.15 EGD99171.1 - 8.1e-06 25.8 0.2 1.4e-05 25.0 0.1 1.4 1 1 0 1 1 1 1 ribonuclease LsmAD PF06741.8 EGD99172.1 - 2.7e-26 91.4 5.9 2.7e-26 91.4 4.1 2.1 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 EGD99172.1 - 3.6e-13 49.2 0.0 9.7e-13 47.8 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain AIP3 PF03915.8 EGD99173.1 - 5.5e-153 509.8 3.8 5.5e-153 509.8 2.7 1.6 2 0 0 2 2 2 1 Actin interacting protein 3 Lectin_N PF03954.9 EGD99173.1 - 0.015 14.6 0.1 0.015 14.6 0.1 2.5 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF3138 PF11336.3 EGD99173.1 - 0.057 11.6 0.7 0.1 10.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1664 PF07889.7 EGD99173.1 - 4.7 7.0 8.6 0.31 10.8 0.4 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Granulin PF00396.13 EGD99174.1 - 0.012 15.6 4.2 0.012 15.6 2.9 6.2 3 3 2 5 5 5 0 Granulin DUF3761 PF12587.3 EGD99174.1 - 0.31 11.1 4.2 0.11 12.5 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3761) Mito_fiss_reg PF05308.6 EGD99174.1 - 1.1 8.5 10.7 1.8 7.8 7.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator ACOX PF01756.14 EGD99175.1 - 2.7e-35 121.4 0.0 5.4e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EGD99175.1 - 4.5e-30 104.5 0.7 9.1e-30 103.5 0.5 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EGD99175.1 - 1.1e-11 44.0 0.3 3e-11 42.6 0.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EGD99175.1 - 7.6e-08 32.5 0.0 0.00042 20.4 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain ESSS PF10183.4 EGD99176.1 - 6e-27 94.1 0.0 6.9e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RNB PF00773.14 EGD99177.1 - 2e-94 316.5 0.1 3.9e-94 315.5 0.1 1.5 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EGD99177.1 - 1.9e-11 44.1 0.7 5.6e-11 42.6 0.2 2.1 2 0 0 2 2 2 1 PIN domain MFS_1 PF07690.11 EGD99178.1 - 4.9e-21 74.8 48.8 1.3e-12 47.1 12.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LIM PF00412.17 EGD99179.1 - 1.1e-27 95.8 20.6 1.2e-10 41.3 2.0 4.0 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.1 EGD99179.1 - 0.014 15.6 0.6 0.057 13.6 0.0 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Methyltransf_4 PF02390.12 EGD99180.1 - 8e-48 162.1 0.0 3.3e-47 160.0 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGD99180.1 - 5.9e-05 23.6 0.0 0.0001 22.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD99180.1 - 0.0034 17.4 0.0 0.012 15.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD99180.1 - 0.011 15.3 0.0 0.026 14.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGD99180.1 - 0.011 16.1 0.0 0.041 14.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EGD99180.1 - 0.016 14.5 0.0 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EGD99180.1 - 0.016 15.6 0.0 0.054 13.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 EGD99180.1 - 0.03 13.3 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.7 EGD99180.1 - 0.035 14.5 0.0 1.6 9.2 0.0 3.1 4 0 0 4 4 4 0 Methyltransferase domain ESCRT-II PF05871.7 EGD99181.1 - 1.9e-51 173.6 0.6 2.9e-51 173.0 0.3 1.4 1 1 1 2 2 2 1 ESCRT-II complex subunit BRCT PF00533.21 EGD99182.1 - 5.9e-35 119.2 0.1 1.2e-07 31.7 0.0 6.5 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGD99182.1 - 3.3e-29 100.5 0.2 2.7e-17 62.3 0.3 5.4 6 0 0 6 6 6 4 twin BRCT domain Abhydrolase_6 PF12697.2 EGD99183.1 - 5e-22 78.9 0.0 1e-21 77.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD99183.1 - 0.00025 20.8 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD99183.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold IL8 PF00048.15 EGD99183.1 - 0.12 12.3 0.5 0.26 11.2 0.3 1.6 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like Ndr PF03096.9 EGD99183.1 - 0.14 10.5 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family Ceramidase PF05875.7 EGD99184.1 - 3.4e-105 350.9 10.6 4e-105 350.6 7.3 1.0 1 0 0 1 1 1 1 Ceramidase Oxidored_q2 PF00420.19 EGD99184.1 - 0.22 11.1 3.7 0.21 11.1 0.7 2.1 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF788 PF05620.6 EGD99184.1 - 0.91 9.3 2.7 0.41 10.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF788) YqhR PF11085.3 EGD99184.1 - 0.93 9.0 7.5 5.1 6.6 0.1 2.4 2 1 0 2 2 2 0 Conserved membrane protein YqhR Toxin_29 PF08116.6 EGD99185.1 - 0.13 12.0 0.7 0.13 12.0 0.5 3.4 4 0 0 4 4 4 0 PhTx neurotoxin family Nodulin_late PF07127.6 EGD99185.1 - 0.23 11.6 6.7 2.5 8.3 0.7 3.0 2 1 1 3 3 3 0 Late nodulin protein FOLN PF09289.5 EGD99185.1 - 1.4 8.8 6.6 0.43 10.4 0.4 3.2 2 1 1 3 3 3 0 Follistatin/Osteonectin-like EGF domain RTA1 PF04479.8 EGD99187.1 - 4.9e-13 49.0 9.7 1.9e-12 47.1 6.7 1.8 1 1 0 1 1 1 1 RTA1 like protein Claudin_3 PF06653.6 EGD99187.1 - 0.059 13.0 4.9 0.15 11.7 3.4 1.8 1 0 0 1 1 1 0 Tight junction protein, Claudin-like TMEM125 PF15109.1 EGD99187.1 - 0.072 13.1 1.6 0.18 11.8 1.1 1.7 1 0 0 1 1 1 0 TMEM125 protein family BTB PF00651.26 EGD99189.1 - 6.4e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain HAD PF12710.2 EGD99190.1 - 1.7e-11 44.6 0.0 2.3e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EGD99190.1 - 7.6e-05 22.1 0.0 0.00046 19.5 0.0 2.0 1 1 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 EGD99190.1 - 9.3e-05 22.7 0.0 0.00038 20.7 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EGD99190.1 - 0.00032 19.9 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase HECT PF00632.20 EGD99191.1 - 1.9e-83 280.2 0.0 9e-83 278.0 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 EGD99191.1 - 0.012 15.6 0.5 0.83 9.9 0.1 3.7 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.18 EGD99191.1 - 0.019 14.7 5.8 8.8 6.3 0.1 5.7 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EGD99191.1 - 0.024 12.9 0.1 0.024 12.9 0.0 2.2 3 0 0 3 3 3 0 Adaptin N terminal region F-box-like PF12937.2 EGD99193.1 - 0.03 14.0 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 F-box-like MIP-T3 PF10243.4 EGD99194.1 - 0.00018 20.1 17.4 0.00018 20.1 12.1 2.1 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 FAM24 PF15193.1 EGD99194.1 - 0.049 13.8 0.7 17 5.6 0.1 2.9 2 0 0 2 2 2 0 FAM24 family COesterase PF00135.23 EGD99195.1 - 2.4e-94 316.9 0.0 1.3e-92 311.2 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD99195.1 - 1.9e-09 37.4 0.0 4.6e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD99195.1 - 0.033 13.9 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3185 PF11381.3 EGD99195.1 - 0.12 12.1 1.5 0.32 10.7 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) F-actin_cap_A PF01267.12 EGD99196.1 - 5.2e-91 304.4 0.0 5.8e-91 304.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DGF-1_C PF11040.3 EGD99197.1 - 0.081 12.8 0.6 0.28 11.0 0.4 1.9 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Med7 PF05983.6 EGD99200.1 - 1.3e-46 158.3 0.0 1.7e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 MED7 protein Prenyltransf PF01255.14 EGD99200.1 - 0.066 12.3 0.1 0.098 11.7 0.1 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase HEAT_2 PF13646.1 EGD99201.1 - 1.7e-20 73.0 1.2 3.1e-05 24.1 0.0 8.3 5 3 1 8 8 8 5 HEAT repeats HEAT PF02985.17 EGD99201.1 - 4.4e-20 69.9 5.8 0.00016 21.4 0.1 9.2 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.1 EGD99201.1 - 3.8e-17 62.2 4.3 0.0023 18.3 0.0 11.2 10 4 3 13 13 11 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGD99201.1 - 1.4e-07 31.8 0.0 1.4 9.3 0.0 6.3 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EGD99201.1 - 8.1e-07 29.0 3.4 0.077 12.8 0.1 4.6 5 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 EGD99201.1 - 6.2e-06 26.1 0.0 0.33 10.9 0.0 5.0 5 0 0 5 5 5 2 UME (NUC010) domain MMS19_C PF12460.3 EGD99201.1 - 2.5e-05 23.1 0.6 0.0018 17.0 0.0 3.6 3 2 0 3 3 3 1 RNAPII transcription regulator C-terminal IBN_N PF03810.14 EGD99201.1 - 4.8e-05 23.1 1.7 0.00018 21.3 0.2 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain ParcG PF10274.4 EGD99201.1 - 0.00034 20.5 0.1 0.039 13.8 0.0 2.9 2 0 0 2 2 2 1 Parkin co-regulated protein CLASP_N PF12348.3 EGD99201.1 - 0.001 18.4 0.9 0.24 10.7 0.0 4.3 5 1 0 5 5 5 1 CLASP N terminal Xpo1 PF08389.7 EGD99201.1 - 0.039 13.8 0.6 2.5 8.0 0.0 4.2 5 1 0 5 5 4 0 Exportin 1-like protein Cohesin_HEAT PF12765.2 EGD99201.1 - 0.044 13.7 0.0 1 9.4 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DUF1839 PF08893.5 EGD99201.1 - 0.078 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) Patched PF02460.13 EGD99202.1 - 6.9e-75 252.4 6.5 3.9e-74 250.0 4.5 1.9 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EGD99202.1 - 3.2e-52 176.0 5.7 3.2e-52 176.0 4.0 3.0 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EGD99202.1 - 2e-07 30.0 8.1 2e-07 30.0 5.6 3.6 4 1 0 4 4 4 1 MMPL family DUF2433 PF10360.4 EGD99203.1 - 3.7e-53 179.3 0.0 6e-53 178.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.23 EGD99203.1 - 0.001 18.5 0.0 0.0026 17.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD99203.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2360 PF10152.4 EGD99203.1 - 7.2 6.8 18.8 0.12 12.6 0.7 3.5 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) PAP1 PF08601.5 EGD99204.1 - 9.1e-56 190.0 40.4 4.7e-55 187.6 24.5 3.3 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EGD99204.1 - 1.8e-08 34.1 8.1 3.9e-08 33.1 5.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor SlyX PF04102.7 EGD99204.1 - 0.011 16.0 0.3 0.026 14.8 0.2 1.6 1 0 0 1 1 1 0 SlyX bZIP_2 PF07716.10 EGD99204.1 - 0.013 15.2 11.1 0.013 15.2 7.7 2.2 2 1 1 3 3 3 0 Basic region leucine zipper COG7 PF10191.4 EGD99204.1 - 0.022 12.7 0.1 0.032 12.1 0.1 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF16 PF01519.11 EGD99204.1 - 0.024 14.8 2.0 0.046 13.9 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 bZIP_Maf PF03131.12 EGD99204.1 - 0.15 12.3 10.1 0.36 11.1 7.0 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 EGD99204.1 - 0.15 11.6 3.5 0.25 10.9 2.4 1.3 1 0 0 1 1 1 0 IncA protein XhlA PF10779.4 EGD99204.1 - 0.35 10.8 3.1 0.87 9.5 2.2 1.7 1 0 0 1 1 1 0 Haemolysin XhlA DUF4537 PF15057.1 EGD99205.1 - 0.0071 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.6 EGD99205.1 - 0.036 13.6 0.5 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 SGF29 tudor-like domain Fis1_TPR_C PF14853.1 EGD99205.1 - 0.17 11.7 0.2 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TRAUB PF08164.7 EGD99206.1 - 7.9e-33 112.4 0.1 2.6e-32 110.7 0.0 2.0 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EGD99206.1 - 3.6e-30 104.7 1.0 3.6e-30 104.7 0.7 2.6 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor ParA PF10609.4 EGD99207.1 - 1.9e-32 110.9 0.4 3.7e-32 110.0 0.0 1.7 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EGD99207.1 - 1.3e-12 47.4 0.0 2.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGD99207.1 - 0.00012 22.0 0.0 0.00086 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EGD99207.1 - 0.029 13.4 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ ArsA_ATPase PF02374.10 EGD99207.1 - 0.19 10.7 0.3 3.9 6.4 0.1 2.5 2 1 1 3 3 3 0 Anion-transporting ATPase Abhydrolase_3 PF07859.8 EGD99208.1 - 1e-33 116.7 0.0 2.6e-25 89.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EGD99208.1 - 3.4e-15 55.5 0.0 9.1e-15 54.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGD99208.1 - 0.054 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 EGD99208.1 - 0.066 11.9 0.0 7.1 5.2 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family WGG PF10273.4 EGD99209.1 - 4.7e-30 103.5 0.1 8.3e-30 102.7 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF4255 PF14065.1 EGD99209.1 - 0.0051 16.2 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4255) NOA36 PF06524.7 EGD99209.1 - 0.092 11.9 4.4 0.12 11.6 3.1 1.1 1 0 0 1 1 1 0 NOA36 protein Herpes_UL49_2 PF04823.7 EGD99209.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein RRP7 PF12923.2 EGD99209.1 - 0.43 10.5 3.1 0.2 11.6 0.6 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Trypan_PARP PF05887.6 EGD99209.1 - 8 6.2 8.6 15 5.4 6.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Tht1 PF04163.7 EGD99210.1 - 3.1e-07 29.1 12.4 4.3e-06 25.4 6.3 2.6 2 1 0 2 2 2 2 Tht1-like nuclear fusion protein Spore_IV_A PF09547.5 EGD99210.1 - 0.014 14.1 0.2 0.021 13.5 0.1 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) TFIID_20kDa PF03847.8 EGD99210.1 - 0.05 13.8 0.0 1.6 9.0 0.0 2.8 2 1 0 2 2 2 0 Transcription initiation factor TFIID subunit A Fez1 PF06818.10 EGD99210.1 - 0.16 11.9 7.0 0.14 12.1 4.0 1.5 1 1 0 1 1 1 0 Fez1 Reo_sigmaC PF04582.7 EGD99210.1 - 0.63 9.1 10.4 0.36 9.9 3.2 2.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EGD99210.1 - 0.7 9.7 15.1 1.3 8.7 1.4 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L6 PF00347.18 EGD99211.1 - 1.8e-22 79.5 0.0 2e-12 47.4 0.0 2.5 3 0 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 EGD99212.1 - 5.4e-52 176.7 0.5 1e-51 175.8 0.4 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family VHS PF00790.14 EGD99213.1 - 2.3e-26 92.1 0.0 4.2e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EGD99213.1 - 0.00014 21.7 0.9 0.00035 20.4 0.5 1.8 1 1 0 1 1 1 1 GAT domain ENTH PF01417.15 EGD99213.1 - 0.00026 20.8 0.1 0.00097 18.9 0.0 1.9 2 0 0 2 2 2 1 ENTH domain RPN7 PF10602.4 EGD99213.1 - 0.045 13.1 1.2 0.096 12.0 0.9 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 adh_short_C2 PF13561.1 EGD99214.1 - 4.4e-15 56.1 0.3 2e-13 50.6 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD99214.1 - 2.9e-09 37.0 9.5 1.2e-07 31.8 2.1 3.1 1 1 1 2 2 2 2 short chain dehydrogenase FHA PF00498.21 EGD99214.1 - 0.068 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 FHA domain KR PF08659.5 EGD99214.1 - 0.1 12.2 7.0 0.64 9.6 0.4 2.6 2 1 0 2 2 2 0 KR domain AdoHcyase_NAD PF00670.16 EGD99214.1 - 0.12 12.1 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF2945 PF11160.3 EGD99215.1 - 6.5e-21 73.9 0.2 8.2e-21 73.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) CP2 PF04516.10 EGD99217.1 - 2.6e-69 232.8 0.0 3.8e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor DEAD PF00270.24 EGD99218.1 - 1.6e-43 148.0 0.0 4.8e-43 146.5 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD99218.1 - 6.3e-22 77.2 0.0 1.4e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EGD99218.1 - 0.00013 20.5 0.0 0.024 13.0 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1253) SNF2_N PF00176.18 EGD99218.1 - 0.00016 20.6 0.0 0.00034 19.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGD99218.1 - 0.00026 20.8 0.2 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGD99218.1 - 0.039 14.1 0.2 0.18 11.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.2 EGD99219.1 - 4.1e-52 174.4 0.0 1.4e-20 73.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGD99219.1 - 2.1e-36 121.8 0.0 1.2e-07 31.2 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EGD99219.1 - 5.2e-35 119.2 0.0 5.3e-09 36.3 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD99219.1 - 1.6e-29 98.9 0.0 3.1e-05 23.7 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EGD99219.1 - 5.6e-22 77.2 0.0 9.6e-05 22.5 0.0 5.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) AAA_16 PF13191.1 EGD99219.1 - 1.2e-05 25.4 0.2 5.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EGD99219.1 - 2e-05 24.3 0.0 6.3e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EGD99219.1 - 0.045 12.7 0.0 0.47 9.3 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain Rad52_Rad22 PF04098.10 EGD99219.1 - 0.066 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein AAA_10 PF12846.2 EGD99219.1 - 0.075 12.4 0.0 0.25 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 EGD99219.1 - 0.084 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsJ PF01728.14 EGD99220.1 - 7.1e-63 211.8 0.0 8.8e-63 211.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EGD99220.1 - 0.015 15.8 0.0 0.42 11.2 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain NSP13 PF06460.7 EGD99220.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Coronavirus NSP13 FAD_binding_1 PF00667.15 EGD99221.1 - 1.3e-53 181.7 0.0 1.9e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EGD99221.1 - 1e-11 45.3 0.0 3.9e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain GAS PF13851.1 EGD99224.1 - 0.0076 15.4 3.1 0.0097 15.1 2.1 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cast PF10174.4 EGD99224.1 - 0.016 13.2 5.1 0.022 12.8 3.5 1.3 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Spc97_Spc98 PF04130.8 EGD99224.1 - 0.094 11.0 0.2 0.1 10.8 0.1 1.0 1 0 0 1 1 1 0 Spc97 / Spc98 family Seryl_tRNA_N PF02403.17 EGD99224.1 - 0.12 12.4 3.1 0.15 12.0 2.2 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rho_Binding PF08912.6 EGD99224.1 - 0.25 11.6 3.6 2.9 8.2 2.4 2.4 1 1 0 1 1 1 0 Rho Binding Ketoacyl-synt_C PF02801.17 EGD99225.1 - 4.9e-29 100.6 0.1 1.5e-28 99.0 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Beta-lactamase PF00144.19 EGD99225.1 - 3.8e-18 65.5 0.0 1.2e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase ketoacyl-synt PF00109.21 EGD99225.1 - 4.9e-18 65.5 0.2 9.8e-18 64.5 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.20 EGD99225.1 - 1.6e-05 25.0 0.1 4.6e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Acyl_transf_1 PF00698.16 EGD99225.1 - 6e-05 22.5 0.1 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Thiolase_N PF00108.18 EGD99225.1 - 0.0011 18.0 0.0 0.0034 16.4 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EGD99225.1 - 0.12 11.9 0.5 0.59 9.8 0.1 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MFS_1 PF07690.11 EGD99226.1 - 1.2e-45 155.8 50.9 6.6e-38 130.3 14.8 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD99226.1 - 6.6e-17 61.2 13.4 6.6e-17 61.2 9.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EGD99226.1 - 2.6e-09 35.8 7.7 2.6e-09 35.8 5.3 2.3 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EGD99226.1 - 0.005 15.0 9.0 0.017 13.2 2.1 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Proteasome PF00227.21 EGD99227.1 - 1.5e-60 203.7 0.1 1.8e-60 203.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGD99227.1 - 2.9e-14 52.0 0.4 6.9e-14 50.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EGD99227.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FF PF01846.14 EGD99228.1 - 6.6e-12 45.1 6.1 1.3e-09 37.8 0.0 3.8 3 0 0 3 3 3 2 FF domain WW PF00397.21 EGD99228.1 - 5.5e-09 35.7 6.9 1.2e-08 34.5 2.1 2.7 2 0 0 2 2 2 1 WW domain BPL_N PF09825.4 EGD99228.1 - 0.14 10.9 3.8 0.24 10.1 2.6 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal AKNA PF12443.3 EGD99229.1 - 0.088 12.8 4.3 0.13 12.3 2.3 1.8 1 1 0 1 1 1 0 AT-hook-containing transcription factor TFIIS_M PF07500.9 EGD99231.1 - 2.3e-21 75.9 0.0 5e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EGD99231.1 - 5.8e-19 68.7 0.0 1.1e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EGD99231.1 - 2.8e-10 39.7 11.5 4.9e-10 38.9 7.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EGD99231.1 - 0.025 13.8 4.5 0.041 13.1 3.1 1.4 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.1 EGD99231.1 - 0.031 14.5 4.8 0.13 12.4 3.3 2.1 1 1 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx LUC7 PF03194.10 EGD99232.1 - 1e-71 241.4 0.1 1.3e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DASH_Duo1 PF08651.5 EGD99232.1 - 0.072 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 TelA PF05816.6 EGD99232.1 - 0.073 11.7 0.3 0.11 11.1 0.2 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) AAA_13 PF13166.1 EGD99232.1 - 0.093 11.1 0.6 0.13 10.7 0.4 1.2 1 0 0 1 1 1 0 AAA domain GRP PF07172.6 EGD99232.1 - 0.32 11.4 20.0 0.54 10.7 13.9 1.3 1 0 0 1 1 1 0 Glycine rich protein family Gpi16 PF04113.9 EGD99233.1 - 2.1e-233 775.4 0.0 2.7e-233 775.1 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component VMA21 PF09446.5 EGD99234.1 - 7.7e-11 41.7 5.4 9.9e-11 41.4 3.7 1.2 1 0 0 1 1 1 1 VMA21-like domain Silic_transp PF03842.8 EGD99234.1 - 0.12 10.3 0.0 0.13 10.3 0.0 1.0 1 0 0 1 1 1 0 Silicon transporter DUF2406 PF10295.4 EGD99235.1 - 3.5e-21 75.4 0.1 3.5e-21 75.4 0.0 3.7 4 0 0 4 4 4 1 Uncharacterised protein (DUF2406) Ribosomal_L35Ae PF01247.13 EGD99236.1 - 4.9e-30 103.1 4.2 1.9e-28 98.0 0.7 2.0 1 1 1 2 2 2 2 Ribosomal protein L35Ae SRF-TF PF00319.13 EGD99237.1 - 1.3e-23 81.9 0.2 2.2e-23 81.2 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1708 PF08101.6 EGD99238.1 - 1.2e-148 495.4 0.0 1.6e-148 495.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF45 PF01863.12 EGD99238.1 - 0.015 15.1 1.4 0.015 15.1 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF45 DUF3602 PF12223.3 EGD99239.1 - 5.2e-16 58.7 12.8 3e-13 49.9 2.3 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 EGD99239.1 - 0.77 9.4 6.5 1.8 8.2 0.2 2.6 2 1 0 3 3 3 0 GTP1/OBG FAD_binding_4 PF01565.18 EGD99244.1 - 2e-17 62.9 1.3 3.4e-17 62.2 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD99244.1 - 0.0025 17.6 0.6 0.0074 16.1 0.4 1.8 1 0 0 1 1 1 1 Berberine and berberine like ERG4_ERG24 PF01222.12 EGD99245.1 - 7.1e-146 486.1 16.4 8.4e-146 485.8 11.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family GTP1_OBG PF01018.17 EGD99246.1 - 1.1e-34 119.3 2.6 2.5e-25 88.9 1.9 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EGD99246.1 - 5.6e-21 74.6 0.0 1.5e-20 73.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGD99246.1 - 8.5e-08 31.6 0.0 1.8e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EGD99246.1 - 0.0053 15.5 0.1 0.22 10.2 0.0 2.2 2 0 0 2 2 2 1 ArgK protein ABC_tran PF00005.22 EGD99246.1 - 0.082 13.2 2.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 EGD99246.1 - 0.17 11.6 0.1 6.9 6.4 0.0 2.6 1 1 1 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 EGD99246.1 - 0.18 11.1 0.0 12 5.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain UQ_con PF00179.21 EGD99247.1 - 3.8e-10 39.3 0.1 7.5e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGD99247.1 - 0.045 13.6 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 RWD domain 2OG-FeII_Oxy_2 PF13532.1 EGD99249.1 - 3.8e-34 118.2 0.2 6e-34 117.5 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.11 EGD99249.1 - 4.6e-06 26.0 0.0 9.8e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain zf-GRF PF06839.7 EGD99249.1 - 0.0015 18.3 8.5 0.0031 17.3 5.9 1.5 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 EGD99249.1 - 0.053 13.8 0.1 0.22 11.8 0.1 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Cupin_8 PF13621.1 EGD99250.1 - 7.7e-35 120.5 0.0 1.6e-34 119.5 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGD99250.1 - 1.3e-06 27.9 0.0 0.00088 18.6 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 EGD99250.1 - 0.0088 16.2 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EGD99250.1 - 0.077 12.5 0.0 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 Cupin domain PLA2_B PF01735.13 EGD99250.1 - 0.19 9.8 0.0 0.28 9.2 0.0 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Homeobox_KN PF05920.6 EGD99251.1 - 2.3e-14 52.7 0.3 6.6e-14 51.3 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.11 EGD99251.1 - 3.9e-05 23.3 0.0 0.00015 21.4 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Homeobox PF00046.24 EGD99251.1 - 0.00026 20.5 0.1 0.00053 19.5 0.0 1.6 1 0 0 1 1 1 1 Homeobox domain HA PF03457.9 EGD99251.1 - 0.012 15.6 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 Helicase associated domain Fungal_trans PF04082.13 EGD99252.1 - 2.6e-29 101.8 0.0 6.3e-29 100.6 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD99252.1 - 3.2e-08 33.3 13.3 5.2e-08 32.6 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 EGD99252.1 - 2.4 7.4 28.2 0.28 10.5 13.3 2.5 2 0 0 2 2 2 0 Vta1 like DnaJ PF00226.26 EGD99253.1 - 1.2e-21 76.2 1.4 2.4e-21 75.2 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain Adenylsucc_synt PF00709.16 EGD99254.1 - 5.6e-81 272.3 0.0 6.2e-81 272.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ank_2 PF12796.2 EGD99255.1 - 4.1e-53 177.6 28.5 1.2e-09 38.3 0.0 12.5 4 4 9 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 EGD99255.1 - 3.2e-38 127.6 40.8 0.017 14.9 0.0 20.8 22 1 0 22 22 22 13 Ankyrin repeat Ank_4 PF13637.1 EGD99255.1 - 3.8e-23 81.4 20.8 0.0092 16.4 0.0 13.9 12 3 1 13 13 13 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD99255.1 - 1.4e-20 72.8 12.0 0.18 12.0 0.0 12.5 12 1 1 13 13 13 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD99255.1 - 4.9e-16 57.2 19.0 1.2 9.6 0.0 18.4 22 1 1 23 23 23 3 Ankyrin repeat DEAD PF00270.24 EGD99256.1 - 1.2e-40 138.7 0.1 1.8e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD99256.1 - 4.1e-19 68.2 0.5 8.1e-19 67.2 0.3 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD99256.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Aldolase_II PF00596.16 EGD99257.1 - 1.7e-44 151.6 0.1 2.3e-44 151.1 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Diacid_rec PF05651.8 EGD99257.1 - 0.14 11.5 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Putative sugar diacid recognition PLAC8 PF04749.12 EGD99258.1 - 4e-20 72.3 13.6 4.9e-20 72.0 9.4 1.1 1 0 0 1 1 1 1 PLAC8 family Abhydrolase_3 PF07859.8 EGD99260.1 - 2.3e-33 115.5 0.0 4.7e-33 114.5 0.0 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EGD99260.1 - 0.0017 18.6 0.0 0.0021 18.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EGD99260.1 - 0.005 16.5 0.0 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD99260.1 - 0.0052 16.6 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGD99260.1 - 0.096 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Nol1_Nop2_Fmu PF01189.12 EGD99261.1 - 7.9e-37 127.1 0.0 1.3e-15 57.5 0.0 4.1 2 1 2 4 4 4 4 NOL1/NOP2/sun family Ubie_methyltran PF01209.13 EGD99261.1 - 0.18 10.9 0.0 0.71 8.9 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF3816 PF12822.2 EGD99262.1 - 0.0099 15.7 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3816) DUF2968 PF11180.3 EGD99264.1 - 0.0034 16.7 10.5 0.0034 16.7 7.3 4.4 2 1 3 5 5 5 1 Protein of unknown function (DUF2968) APG6 PF04111.7 EGD99264.1 - 0.081 11.9 49.5 0.01 14.8 12.7 3.2 2 1 1 3 3 3 0 Autophagy protein Apg6 KxDL PF10241.4 EGD99264.1 - 0.13 12.1 14.5 0.26 11.2 0.1 4.1 2 1 0 3 3 3 0 Uncharacterized conserved protein Spectrin PF00435.16 EGD99264.1 - 0.22 11.8 34.4 0.03 14.5 6.3 3.7 3 1 0 3 3 3 0 Spectrin repeat MscS_porin PF12795.2 EGD99264.1 - 0.93 8.7 49.9 0.21 10.8 9.4 3.5 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Occludin_ELL PF07303.8 EGD99264.1 - 2.9 8.6 35.1 0.23 12.2 6.7 4.4 2 1 2 4 4 4 0 Occludin homology domain Reo_sigmaC PF04582.7 EGD99264.1 - 5.7 6.0 11.8 0.4 9.8 1.4 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EGD99264.1 - 6.1 6.6 20.9 1.7 8.4 2.3 3.9 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EGD99264.1 - 7.1 6.4 16.3 1.3 8.8 2.3 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_Rpb5_C PF01191.14 EGD99265.1 - 9.1e-31 105.2 0.2 1.6e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EGD99265.1 - 1.3e-30 105.6 0.0 2e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EGD99265.1 - 0.0008 19.2 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease AMP-binding PF00501.23 EGD99267.1 - 5.6e-46 156.7 0.0 7.7e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD99267.1 - 6.1e-05 23.8 0.0 0.00014 22.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-C2H2_jaz PF12171.3 EGD99268.1 - 1.7e-07 31.1 0.3 3.5e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGD99268.1 - 2.9e-06 27.2 0.5 7.5e-06 25.9 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EGD99268.1 - 0.0023 18.1 0.4 0.0046 17.2 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EGD99268.1 - 0.093 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) EVC2_like PF12297.3 EGD99268.1 - 0.12 11.0 5.3 0.17 10.4 3.6 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein BIR PF00653.16 EGD99269.1 - 3.3e-40 136.3 7.9 4e-20 71.9 0.1 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Mmp37 PF09139.6 EGD99270.1 - 6.3e-137 456.0 0.0 7.6e-137 455.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Aminotran_1_2 PF00155.16 EGD99272.1 - 2.9e-63 214.0 0.0 3.4e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGD99272.1 - 0.005 15.1 0.1 0.011 14.0 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EGD99272.1 - 0.016 13.9 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V TFIID-18kDa PF02269.11 EGD99273.1 - 1.7e-30 104.6 0.4 1.9e-29 101.2 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TP_methylase PF00590.15 EGD99274.1 - 7.8e-21 74.7 0.1 1.2e-20 74.1 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Clat_adaptor_s PF01217.15 EGD99276.1 - 1.7e-54 183.4 2.3 2e-54 183.1 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AMP-binding PF00501.23 EGD99277.1 - 3.1e-59 200.4 0.0 4e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD99277.1 - 0.0026 18.6 0.0 0.007 17.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DAHP_synth_2 PF01474.11 EGD99279.1 - 2.2e-74 250.3 0.4 4.2e-50 170.3 0.1 2.0 2 0 0 2 2 2 2 Class-II DAHP synthetase family Peptidase_S28 PF05577.7 EGD99280.1 - 3.4e-56 190.6 0.5 5.7e-56 189.9 0.4 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Ist1 PF03398.9 EGD99282.1 - 1.9e-30 105.4 0.5 1.6e-14 53.6 0.9 2.1 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway zf-C3HC4 PF00097.20 EGD99283.1 - 9.8e-09 34.7 8.3 2e-07 30.5 5.7 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD99283.1 - 2e-08 33.8 3.2 7.2e-08 32.0 2.2 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGD99283.1 - 2.6e-08 33.5 4.3 2.6e-08 33.5 3.0 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGD99283.1 - 6.8e-07 28.8 6.0 1.8e-06 27.4 4.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD99283.1 - 5.8e-06 26.2 9.5 8e-05 22.5 6.6 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGD99283.1 - 0.00094 18.8 0.9 0.00094 18.8 0.6 2.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGD99283.1 - 0.0036 17.1 2.1 0.0036 17.1 1.4 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-CCCH PF00642.19 EGD99283.1 - 0.01 15.4 15.8 0.069 12.8 0.9 3.4 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-Apc11 PF12861.2 EGD99283.1 - 0.031 14.1 1.4 1.4 8.8 0.3 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger YyzF PF14116.1 EGD99283.1 - 0.037 13.9 0.2 6.6 6.7 0.0 2.7 2 0 0 2 2 2 0 YyzF-like protein zf-rbx1 PF12678.2 EGD99283.1 - 0.14 12.2 7.8 1.4 9.0 3.4 2.9 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_6 PF14835.1 EGD99283.1 - 0.32 10.8 5.0 0.23 11.2 1.5 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein SUN PF03856.8 EGD99284.1 - 4.7e-77 258.6 13.0 6.6e-77 258.1 9.0 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF572 PF04502.8 EGD99284.1 - 6.5 5.8 8.8 9.4 5.3 6.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) LCM PF04072.9 EGD99285.1 - 1.3e-22 80.2 0.0 2.1e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase zf-RING_2 PF13639.1 EGD99286.1 - 2.8e-07 30.2 10.3 6.1e-07 29.1 7.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGD99286.1 - 9.9e-06 25.5 3.3 2.5e-05 24.2 2.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGD99286.1 - 0.00018 21.2 4.1 0.00043 20.0 2.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EGD99286.1 - 0.0012 18.7 6.9 0.0027 17.6 4.8 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 EGD99286.1 - 0.0043 16.6 13.0 0.0093 15.6 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD99286.1 - 0.037 14.0 12.7 0.09 12.8 8.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EGD99286.1 - 0.4 10.7 10.2 0.87 9.6 7.1 1.6 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EGD99286.1 - 0.42 10.3 8.7 0.15 11.8 3.9 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Nse PF11789.3 EGD99286.1 - 1.5 8.3 5.7 4.1 7.0 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 EGD99286.1 - 1.7 8.6 9.6 4.2 7.4 6.6 1.7 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EGD99286.1 - 4.9 6.8 7.9 13 5.5 5.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1227 PF06777.6 EGD99287.1 - 1e-60 203.6 0.4 2.9e-60 202.1 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EGD99287.1 - 4.2e-51 172.7 0.2 7.3e-51 172.0 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EGD99287.1 - 8.9e-45 152.6 0.0 2.3e-44 151.2 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 EGD99287.1 - 7.8e-05 22.2 0.0 0.021 14.3 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EGD99287.1 - 7.9e-05 21.5 0.0 0.00043 19.1 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGD99287.1 - 0.00049 19.9 0.5 0.0038 17.0 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EGD99287.1 - 0.008 15.7 0.1 0.008 15.7 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGD99287.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EGD99287.1 - 0.086 12.0 0.6 1.4 8.1 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein U1snRNP70_N PF12220.3 EGD99287.1 - 0.096 13.0 1.2 0.34 11.2 0.8 1.9 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Stomoxyn PF11585.3 EGD99287.1 - 0.21 11.3 0.1 0.87 9.4 0.1 2.0 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn RNA_pol_Rpb1_5 PF04998.12 EGD99288.1 - 1.1e-86 290.5 0.0 3.1e-86 289.0 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGD99288.1 - 3.8e-62 209.1 0.1 8.5e-62 207.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGD99288.1 - 1.2e-34 119.2 0.0 4.6e-33 114.1 0.0 2.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EGD99288.1 - 5.1e-27 95.0 2.4 1.1e-18 67.6 0.0 2.7 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EGD99288.1 - 1.6e-17 63.1 0.0 6.4e-17 61.2 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Glyco_hydro_20b PF02838.10 EGD99288.1 - 0.051 14.1 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 PRP3 PF08572.5 EGD99289.1 - 9.1e-72 241.0 3.3 1.5e-71 240.3 2.3 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EGD99289.1 - 2.2e-39 134.0 0.4 2.2e-39 134.0 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Fungal_trans PF04082.13 EGD99290.1 - 1.5e-07 30.6 0.5 3.9e-07 29.2 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD99290.1 - 1.3e-06 28.2 10.5 1.9e-06 27.6 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERCC4 PF02732.10 EGD99291.1 - 6e-30 103.8 0.1 1.2e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EGD99291.1 - 0.0002 21.4 0.1 0.03 14.4 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain E1-E2_ATPase PF00122.15 EGD99292.1 - 3.7e-53 179.9 0.0 1.2e-52 178.2 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGD99292.1 - 2.1e-35 123.1 0.3 3.9e-35 122.2 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EGD99292.1 - 1e-33 115.2 4.4 2.4e-09 37.1 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EGD99292.1 - 2e-18 67.2 0.0 3.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD99292.1 - 2.7e-05 23.8 1.0 0.00074 19.1 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Borrelia_REV PF03978.8 EGD99292.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Equine_IAV_S2 PF06502.6 EGD99293.1 - 0.047 13.5 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein TFIIB PF00382.14 EGD99294.1 - 1.1e-30 105.2 0.5 2.7e-17 62.3 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EGD99294.1 - 2.9e-24 85.1 2.5 4.1e-24 84.6 0.0 2.7 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EGD99294.1 - 0.00044 19.5 2.6 0.00094 18.4 1.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EGD99294.1 - 0.00096 18.7 0.1 0.53 9.8 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain RRN7 PF11781.3 EGD99294.1 - 0.032 13.7 0.1 0.069 12.6 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 IBR PF01485.16 EGD99294.1 - 0.34 10.7 2.6 0.62 9.9 1.8 1.4 1 0 0 1 1 1 0 IBR domain TPT PF03151.11 EGD99296.1 - 3.2e-27 95.0 11.4 3.2e-27 95.0 7.9 3.2 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EGD99296.1 - 2.4e-07 30.0 21.2 4.9e-06 25.6 14.7 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGD99296.1 - 0.69 9.9 32.1 2 8.4 7.4 3.2 3 1 0 3 3 3 0 EamA-like transporter family RNase_H PF00075.19 EGD99299.1 - 3.9e-11 43.4 0.0 4.6e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EGD99299.1 - 5e-09 35.8 0.1 0.0024 17.6 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase-like RNase_H PF00075.19 EGD99300.1 - 2.9e-16 60.0 0.6 3.8e-16 59.6 0.4 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EGD99300.1 - 3.7e-07 29.8 3.9 5.7e-05 22.8 2.7 2.8 1 1 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.19 EGD99301.1 - 3.5e-12 46.8 0.0 4.2e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 RNase H YyzF PF14116.1 EGD99301.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 YyzF-like protein NAD_binding_8 PF13450.1 EGD99302.1 - 5.8e-09 35.8 0.0 1.5e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGD99302.1 - 1.1e-06 28.0 0.0 0.00019 20.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EGD99302.1 - 0.0002 21.4 0.2 0.00046 20.3 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD99302.1 - 0.0043 16.9 0.0 0.048 13.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD99302.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EGD99302.1 - 0.052 12.4 0.0 0.1 11.4 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGD99302.1 - 0.054 12.5 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGD99302.1 - 0.057 12.4 0.1 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EGD99302.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 EGD99302.1 - 0.12 12.0 0.6 0.9 9.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding BLVR PF06375.6 EGD99304.1 - 0.39 10.5 6.5 0.6 9.9 4.5 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Pkinase PF00069.20 EGD99305.1 - 9.5e-65 218.3 0.0 1.2e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD99305.1 - 3.3e-31 108.2 0.0 5.5e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD99305.1 - 2.1e-05 23.7 0.0 3.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD99305.1 - 0.00028 19.9 0.1 0.0014 17.6 0.0 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EGD99305.1 - 0.0049 16.6 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4360 PF14273.1 EGD99306.1 - 2.1e-38 131.7 0.2 2.6e-38 131.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SNARE PF05739.14 EGD99307.1 - 0.0044 16.6 0.6 0.36 10.5 0.0 2.3 2 0 0 2 2 2 2 SNARE domain Pneumovirus_M2 PF06436.6 EGD99307.1 - 0.14 11.3 0.1 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) Sugar_tr PF00083.19 EGD99308.1 - 5.1e-98 328.5 24.9 6.4e-98 328.2 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD99308.1 - 6.2e-21 74.4 29.3 2.7e-15 55.9 2.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.3 EGD99308.1 - 0.035 13.5 5.5 0.084 12.3 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF1228 PF06779.9 EGD99308.1 - 0.052 13.5 7.6 0.99 9.4 0.6 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) zf-CCHC PF00098.18 EGD99310.1 - 7.4e-52 170.9 100.6 1.6e-07 30.8 1.6 11.3 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_3 PF13917.1 EGD99310.1 - 3e-07 30.0 76.7 0.022 14.5 0.6 11.1 3 3 8 11 11 11 8 Zinc knuckle zf-CCHC_4 PF14392.1 EGD99310.1 - 1.1e-05 25.0 74.6 0.17 11.5 0.2 11.1 10 1 1 11 11 11 8 Zinc knuckle zf-CCHC_2 PF13696.1 EGD99310.1 - 0.026 13.9 52.8 0.093 12.2 0.7 9.0 6 3 4 10 10 10 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGD99310.1 - 0.36 10.5 84.4 0.056 13.1 2.2 10.5 8 2 2 10 10 10 0 Zinc knuckle DUF846 PF05832.7 EGD99311.1 - 1.1e-48 164.5 9.7 1.3e-48 164.2 6.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Acyl-CoA_dh_1 PF00441.19 EGD99312.1 - 2.2e-31 109.0 0.1 3e-31 108.5 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGD99312.1 - 4.8e-20 72.2 0.0 1.1e-19 71.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGD99312.1 - 4.9e-17 61.1 0.5 9.3e-17 60.2 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGD99312.1 - 0.0066 16.6 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Bombinin PF05298.6 EGD99312.1 - 0.058 12.8 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Bombinin ECH PF00378.15 EGD99313.1 - 2.4e-41 141.4 0.0 3.2e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Phageshock_PspD PF09584.5 EGD99313.1 - 0.24 11.1 1.2 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 Phage shock protein PspD (Phageshock_PspD) HpcH_HpaI PF03328.9 EGD99314.1 - 1.2e-41 141.9 0.0 1.9e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EGD99314.1 - 4.6e-12 45.4 0.0 6.9e-05 21.8 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Glycoprotein_G PF00802.14 EGD99315.1 - 9.3 5.3 9.1 1.2 8.2 3.2 1.7 1 1 1 2 2 2 0 Pneumovirus attachment glycoprotein G Glyco_transf_90 PF05686.7 EGD99316.1 - 5.3e-17 61.5 3.0 1.4e-10 40.4 1.3 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF3437 PF11919.3 EGD99316.1 - 0.012 15.3 0.5 0.11 12.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Oxidored_molyb PF00174.14 EGD99318.1 - 4.7e-40 136.7 0.0 7.8e-40 136.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EGD99318.1 - 6.9e-37 126.0 0.2 1.6e-36 124.8 0.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 EGD99318.1 - 1.9e-25 89.5 0.0 9.8e-25 87.2 0.0 2.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGD99318.1 - 1.1e-22 80.0 0.0 2e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EGD99318.1 - 1.4e-17 63.2 0.1 4.3e-17 61.6 0.1 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EGD99318.1 - 0.0018 18.2 0.3 0.13 12.1 0.0 2.9 2 1 0 3 3 3 1 Ferric reductase NAD binding domain HTH_38 PF13936.1 EGD99318.1 - 0.061 12.8 0.0 0.21 11.1 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain CAP59_mtransfer PF11735.3 EGD99319.1 - 7e-83 277.5 0.0 9.8e-83 277.0 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF346 PF03984.8 EGD99321.1 - 4e-17 61.3 53.3 0.00089 18.6 3.1 7.2 7 0 0 7 7 7 6 Repeat of unknown function (DUF346) Toxin_42 PF15522.1 EGD99321.1 - 1.4e-05 24.4 0.0 17 4.4 0.0 6.2 7 0 0 7 7 7 1 Putative toxin 42 DUF1724 PF08350.5 EGD99321.1 - 0.0064 15.9 9.7 0.43 10.1 0.0 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF1724) Stap_Strp_toxin PF01123.15 EGD99321.1 - 0.01 16.3 0.0 27 5.3 0.0 5.0 6 1 1 7 7 7 0 Staphylococcal/Streptococcal toxin, OB-fold domain DUF3147 PF11345.3 EGD99321.1 - 0.078 13.0 1.9 1.3e+02 2.6 0.0 5.0 7 0 0 7 7 7 0 Protein of unknown function (DUF3147) DUF2510 PF10708.4 EGD99321.1 - 1.1 8.7 51.9 0.11 11.9 0.5 6.4 6 0 0 6 6 6 0 Protein of unknown function (DUF2510) SNARE_assoc PF09335.6 EGD99322.1 - 6.4e-11 42.5 5.3 6.4e-11 42.5 3.7 2.6 2 1 1 3 3 3 1 SNARE associated Golgi protein 7tm_1 PF00001.16 EGD99322.1 - 0.015 14.4 0.1 0.031 13.3 0.1 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) HAMP PF00672.20 EGD99322.1 - 0.37 11.0 2.9 0.53 10.4 0.0 2.7 3 0 0 3 3 3 0 HAMP domain Amino_oxidase PF01593.19 EGD99323.1 - 1e-89 301.6 0.0 2.8e-89 300.2 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EGD99323.1 - 9e-11 41.7 0.0 2.1e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EGD99323.1 - 1.5e-07 31.3 0.1 3.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EGD99323.1 - 0.00044 20.4 4.9 0.00044 20.4 1.3 2.5 2 1 0 2 2 2 1 HMG (high mobility group) box DAO PF01266.19 EGD99323.1 - 0.002 17.0 0.3 0.034 13.0 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGD99323.1 - 0.066 13.2 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD99323.1 - 0.1 12.4 0.6 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD99323.1 - 0.15 11.8 0.4 1.5 8.5 0.0 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGD99324.1 - 5.3e-27 95.0 0.3 7.1e-27 94.6 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD99324.1 - 1e-15 57.8 0.2 3.9e-13 49.5 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD99324.1 - 4.9e-09 36.5 0.1 9.5e-05 22.5 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD99324.1 - 3.2e-05 23.1 0.4 9.1e-05 21.6 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 EGD99324.1 - 4.4e-05 23.6 0.0 0.015 15.5 0.0 2.6 1 1 1 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EGD99324.1 - 0.00018 21.4 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EGD99324.1 - 0.0055 15.6 0.0 0.62 8.9 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EGD99324.1 - 0.0076 16.3 0.1 2.8 8.0 0.0 2.7 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EGD99324.1 - 0.011 14.6 4.1 1.3 7.8 0.1 3.6 2 2 2 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGD99324.1 - 0.024 13.6 0.3 3.1 6.7 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 EGD99324.1 - 0.1 11.4 4.5 0.28 9.9 0.2 2.9 2 2 0 3 3 3 0 FAD binding domain GIDA PF01134.17 EGD99324.1 - 0.16 10.8 8.0 2.2 7.0 0.2 3.8 3 1 1 5 5 5 0 Glucose inhibited division protein A DUF3799 PF12684.2 EGD99325.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) APH PF01636.18 EGD99326.1 - 2.5e-14 53.5 0.0 3.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD99326.1 - 1.7e-10 40.8 0.0 3.3e-10 39.9 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGD99326.1 - 2e-05 23.8 0.0 0.00035 19.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain DUF2116 PF09889.4 EGD99327.1 - 0.0068 16.1 1.0 0.012 15.3 0.7 1.4 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) p450 PF00067.17 EGD99330.1 - 1.9e-41 142.1 0.0 2.3e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGD99331.1 - 9.6e-44 149.6 0.0 1.1e-43 149.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 EGD99332.1 - 1.1e-07 31.4 0.4 8.5e-05 21.9 0.1 2.6 2 1 0 2 2 2 2 Terpene synthase family, metal binding domain Prenyltrans_1 PF13243.1 EGD99332.1 - 4e-07 30.0 0.0 0.0074 16.2 0.0 3.1 2 1 0 2 2 2 2 Prenyltransferase-like Prenyltrans_2 PF13249.1 EGD99332.1 - 4.5e-06 27.0 0.1 0.016 15.6 0.0 3.8 2 1 1 3 3 3 2 Prenyltransferase-like p450 PF00067.17 EGD99333.1 - 6.5e-45 153.4 0.0 8.5e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EGD99335.1 - 2.4e-21 75.6 0.0 4.3e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD99335.1 - 0.0016 18.3 0.1 0.006 16.4 0.0 2.0 1 0 0 1 1 1 1 Berberine and berberine like Na_Ca_ex PF01699.19 EGD99336.1 - 3.8e-22 78.4 26.9 2.6e-11 43.2 7.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein IncA PF04156.9 EGD99336.1 - 0.32 10.5 0.0 0.32 10.5 0.0 2.3 2 0 0 2 2 2 0 IncA protein p450 PF00067.17 EGD99337.1 - 2.3e-26 92.3 0.0 1.4e-16 60.0 0.0 3.0 1 1 2 3 3 3 3 Cytochrome P450 LysM PF01476.15 EGD99339.1 - 5.2e-09 35.8 0.0 8.2e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 LysM domain DUF3357 PF11837.3 EGD99340.1 - 4.7 7.1 6.3 3.2 7.6 0.8 2.4 2 1 0 3 3 3 0 Domain of unknown function (DUF3357) ADH_zinc_N_2 PF13602.1 EGD99341.1 - 2.1e-11 44.8 0.0 5.4e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD99341.1 - 4.7e-11 42.4 0.0 7.9e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD99341.1 - 9.2e-07 28.4 0.0 2.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DIOX_N PF14226.1 EGD99343.1 - 4.4e-22 78.7 0.0 1e-21 77.6 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGD99343.1 - 2.7e-12 46.8 0.1 4.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp_Glu_race PF01177.17 EGD99344.1 - 1.8e-23 83.6 0.7 2.1e-23 83.3 0.5 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.6 EGD99344.1 - 0.00082 18.7 0.0 0.38 10.0 0.0 2.2 2 0 0 2 2 2 2 AroM protein Pantoate_transf PF02548.10 EGD99344.1 - 0.036 13.1 0.2 1.4 8.0 0.0 2.1 1 1 0 2 2 2 0 Ketopantoate hydroxymethyltransferase MFS_1 PF07690.11 EGD99345.1 - 1.2e-42 145.9 34.6 4.3e-39 134.2 17.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.1 EGD99347.1 - 3.1e-19 69.6 0.0 5.3e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGD99347.1 - 3.1e-14 53.0 0.0 5.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ketoacyl-synt PF00109.21 EGD99348.1 - 2.5e-74 249.9 0.0 4.7e-74 249.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGD99348.1 - 9.3e-44 150.0 2.4 9.8e-44 149.9 0.0 2.3 2 1 1 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGD99348.1 - 7.9e-33 112.8 0.6 7.9e-33 112.8 0.4 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EGD99348.1 - 2.1e-13 50.3 0.1 6.5e-13 48.7 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGD99348.1 - 6.5e-05 22.0 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EGD99348.1 - 0.02 14.6 0.2 0.21 11.3 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family Trp_DMAT PF11991.3 EGD99349.1 - 1.9e-79 267.5 0.0 2.3e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Orexin PF02072.10 EGD99349.1 - 0.0041 16.9 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Prepro-orexin DUF4060 PF13269.1 EGD99349.1 - 0.046 13.6 0.1 6.4 6.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4060) FAD_binding_3 PF01494.14 EGD99350.1 - 7.5e-14 51.5 0.9 5.3e-12 45.4 0.6 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGD99350.1 - 0.0016 17.4 0.0 0.024 13.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EGD99350.1 - 0.0046 16.0 0.0 1.4 7.8 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGD99350.1 - 0.0052 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGD99350.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lactamase_B PF00753.22 EGD99351.1 - 6.1e-20 71.7 0.5 2.5e-19 69.7 0.4 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGD99351.1 - 0.00057 19.4 0.1 0.001 18.6 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGD99351.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Zn_clus PF00172.13 EGD99352.1 - 1.2e-07 31.4 7.1 2.3e-07 30.6 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGD99352.1 - 1.6e-05 23.8 0.2 5e-05 22.3 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-PHD-like PF15446.1 EGD99352.1 - 0.027 13.7 1.4 0.048 12.9 1.0 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Metallophos PF00149.23 EGD99353.1 - 4.5e-10 39.2 2.0 2.4e-07 30.3 0.3 3.1 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Tyrosinase PF00264.15 EGD99355.1 - 7.1e-51 173.4 2.8 7.1e-51 173.4 2.0 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase Fungal_trans PF04082.13 EGD99356.1 - 1.8e-24 86.0 3.0 2.8e-24 85.4 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S8e PF01201.17 EGD99357.1 - 1.1e-28 99.9 0.5 2.5e-28 98.8 0.4 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e RIB43A PF05914.7 EGD99358.1 - 0.006 15.2 0.7 0.008 14.8 0.5 1.1 1 0 0 1 1 1 1 RIB43A Pkinase PF00069.20 EGD99359.1 - 6.2e-49 166.4 0.0 9.1e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD99359.1 - 6.8e-18 64.6 0.0 1.1e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGD99359.1 - 0.00015 21.1 0.2 0.00042 19.7 0.1 1.7 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EGD99359.1 - 0.00023 20.2 0.0 0.00035 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD99359.1 - 0.0019 18.0 0.3 0.33 10.6 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD99359.1 - 0.074 12.1 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PWI PF01480.12 EGD99360.1 - 7.4e-30 102.8 0.1 1.2e-29 102.2 0.1 1.3 1 0 0 1 1 1 1 PWI domain PepSY_TM_3 PF13706.1 EGD99361.1 - 0.0058 16.0 0.3 0.011 15.1 0.2 1.4 1 0 0 1 1 1 1 PepSY-associated TM helix C8 PF08742.6 EGD99361.1 - 0.015 15.5 1.0 0.039 14.1 0.7 1.7 1 0 0 1 1 1 0 C8 domain DUF4366 PF14283.1 EGD99361.1 - 0.041 13.3 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3611 PF12263.3 EGD99361.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) CFEM PF05730.6 EGD99361.1 - 0.18 11.6 4.3 0.32 10.8 3.0 1.4 1 0 0 1 1 1 0 CFEM domain L27 PF02828.11 EGD99362.1 - 0.025 14.2 0.1 0.5 10.0 0.0 2.2 2 0 0 2 2 2 0 L27 domain FAA_hydrolase PF01557.13 EGD99363.1 - 1.7e-52 178.0 0.0 2.2e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family VASP_tetra PF08776.6 EGD99364.1 - 0.00049 19.3 1.3 0.66 9.3 0.0 2.4 2 0 0 2 2 2 2 VASP tetramerisation domain DUF3584 PF12128.3 EGD99364.1 - 0.004 14.5 5.8 0.0056 14.0 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 EGD99364.1 - 0.013 15.3 0.9 0.065 13.0 0.1 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CDC37_N PF03234.9 EGD99364.1 - 0.019 15.3 4.0 4.8 7.4 1.7 2.5 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding Mis14 PF08641.7 EGD99364.1 - 0.035 14.1 4.0 0.078 13.0 2.8 1.6 1 0 0 1 1 1 0 Kinetochore protein Mis14 like HTH_1 PF00126.22 EGD99364.1 - 0.048 13.3 0.8 0.18 11.5 0.5 2.0 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Apolipoprotein PF01442.13 EGD99364.1 - 0.2 11.1 8.3 0.033 13.6 2.5 2.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain IncA PF04156.9 EGD99364.1 - 0.55 9.8 11.2 2.8 7.4 7.7 2.1 1 1 0 1 1 1 0 IncA protein DUF883 PF05957.8 EGD99364.1 - 0.55 10.6 2.7 1.4 9.4 0.8 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mnd1 PF03962.10 EGD99364.1 - 5.9 6.5 8.6 0.54 9.9 0.4 2.5 2 1 1 3 3 3 0 Mnd1 family DEAD PF00270.24 EGD99365.1 - 1.5e-43 148.2 1.4 2.9e-43 147.2 0.7 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD99365.1 - 1.3e-27 95.4 0.2 3.7e-27 93.9 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD99365.1 - 0.00062 19.6 0.1 0.0015 18.3 0.1 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EGD99365.1 - 0.0017 17.9 0.4 0.005 16.4 0.1 1.8 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.1 EGD99365.1 - 0.0097 14.9 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EGD99365.1 - 0.014 15.1 0.1 0.041 13.6 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EGD99365.1 - 0.019 15.1 0.1 0.066 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EGD99365.1 - 0.06 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain tRNA-synt_1b PF00579.20 EGD99365.1 - 0.083 12.0 0.0 0.44 9.6 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.9 EGD99365.1 - 0.096 12.4 0.2 0.59 9.8 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 EGD99365.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Helicase Cupin_8 PF13621.1 EGD99366.1 - 9.7e-16 58.0 0.0 8.9e-15 54.8 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EGD99366.1 - 3.4e-09 36.9 0.1 9.4e-08 32.3 0.1 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 EGD99366.1 - 7.7e-07 28.7 0.0 1.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD99366.1 - 0.00068 19.2 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Ctr PF04145.10 EGD99367.1 - 4.2e-33 114.4 0.6 6.4e-33 113.8 0.4 1.3 1 1 0 1 1 1 1 Ctr copper transporter family DUF1469 PF07332.6 EGD99367.1 - 1.6 8.5 5.1 4.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) NuA4 PF09340.5 EGD99368.1 - 2.7e-27 94.1 0.1 5.1e-27 93.3 0.1 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Pol_alpha_B_N PF08418.5 EGD99368.1 - 3.3 7.1 8.5 8.1 5.8 4.6 2.0 1 1 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Glyco_hydro_38 PF01074.17 EGD99369.1 - 1.9e-90 302.8 0.6 4.3e-90 301.6 0.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EGD99369.1 - 1.2e-68 231.9 0.0 2.3e-68 231.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EGD99369.1 - 1.2e-24 86.3 0.0 2.2e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain NUDIX PF00293.23 EGD99371.1 - 4.4e-11 42.5 0.0 1.5e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain TRM13 PF05206.9 EGD99371.1 - 0.07 12.3 0.0 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase TRM13 GHL12 PF14882.1 EGD99371.1 - 0.074 13.1 0.4 0.17 11.9 0.3 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 LETM1 PF07766.8 EGD99372.1 - 3e-104 347.8 0.1 5.3e-104 346.9 0.1 1.4 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EGD99372.1 - 0.00017 21.0 0.0 0.3 10.6 0.0 3.1 3 0 0 3 3 3 2 SAP domain DUF2838 PF10998.3 EGD99373.1 - 3.3e-41 139.6 10.7 3.3e-41 139.6 7.4 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) Exonuc_VII_L PF02601.10 EGD99373.1 - 0.22 10.6 1.7 0.32 10.1 1.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.9 EGD99373.1 - 2.4 8.0 7.0 0.62 9.9 2.2 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ank_2 PF12796.2 EGD99377.1 - 2.3e-29 101.5 0.0 3.9e-17 62.3 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGD99377.1 - 6.8e-21 72.9 3.9 1.6e-08 33.9 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EGD99377.1 - 4.2e-20 71.7 0.4 7.8e-06 26.2 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD99377.1 - 5e-19 67.8 3.3 7.4e-06 26.0 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD99377.1 - 2.9e-17 61.0 0.7 3.3e-05 23.7 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat SMC_N PF02463.14 EGD99378.1 - 8.1e-60 201.7 0.0 2.2e-37 128.4 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGD99378.1 - 5.2e-31 107.1 0.6 3.4e-30 104.4 0.0 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGD99378.1 - 3.4e-11 43.6 16.8 5.4e-06 26.5 0.1 4.8 3 2 2 5 5 5 2 AAA domain AAA_23 PF13476.1 EGD99378.1 - 4.7e-11 43.3 17.2 4.7e-11 43.3 11.9 6.4 3 2 2 5 5 3 1 AAA domain AAA_29 PF13555.1 EGD99378.1 - 2.6e-08 33.2 0.0 5.7e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4200 PF13863.1 EGD99378.1 - 0.00017 21.5 4.2 0.00017 21.5 2.9 9.0 4 3 5 9 9 5 3 Domain of unknown function (DUF4200) SbcCD_C PF13558.1 EGD99378.1 - 0.0014 18.4 0.1 0.0095 15.8 0.0 2.6 2 0 0 2 2 1 1 Putative exonuclease SbcCD, C subunit ATG16 PF08614.6 EGD99378.1 - 0.0082 15.9 3.2 0.0082 15.9 2.2 7.4 4 2 4 8 8 7 2 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EGD99378.1 - 0.0096 15.1 28.7 0.0084 15.3 2.3 4.9 4 1 2 6 6 6 4 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EGD99378.1 - 0.019 14.7 0.4 0.019 14.7 0.3 8.0 5 2 2 7 7 7 0 TPR/MLP1/MLP2-like protein Patched PF02460.13 EGD99378.1 - 4.3 5.1 6.7 8.3 4.1 4.6 1.4 1 0 0 1 1 1 0 Patched family NPV_P10 PF05531.7 EGD99378.1 - 7.5 6.8 41.7 7.4 6.9 0.2 8.8 7 1 1 8 8 8 0 Nucleopolyhedrovirus P10 protein WH1 PF00568.18 EGD99379.1 - 0.083 12.6 0.1 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 WH1 domain Pex14_N PF04695.8 EGD99379.1 - 0.095 12.7 0.9 0.2 11.7 0.4 1.8 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region E3_binding PF02817.12 EGD99380.1 - 1.4e-09 37.4 0.0 2.2e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 e3 binding domain Abhydrolase_2 PF02230.11 EGD99381.1 - 8.2e-21 74.4 0.0 6.8e-15 55.0 0.0 3.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGD99381.1 - 0.00021 21.0 0.0 0.00044 20.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family HNH_2 PF13391.1 EGD99382.1 - 6.4e-16 57.8 0.1 1.1e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease WD40 PF00400.27 EGD99383.1 - 3.5e-37 124.9 5.9 9.8e-08 31.6 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGD99383.1 - 1.8e-08 34.3 0.1 0.0031 17.2 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A ATPgrasp_ST PF14397.1 EGD99383.1 - 0.055 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Peptidase_M18 PF02127.10 EGD99384.1 - 8.3e-162 538.5 0.0 9.4e-162 538.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Sugar_tr PF00083.19 EGD99385.1 - 2.6e-38 131.7 12.0 5.2e-32 110.9 5.6 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGD99385.1 - 1.2e-27 96.6 26.5 1.1e-23 83.5 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGD99385.1 - 0.0058 14.7 0.0 0.013 13.6 0.0 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family HTH_38 PF13936.1 EGD99385.1 - 0.19 11.2 2.3 0.41 10.2 1.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Hydrolase_6 PF13344.1 EGD99386.1 - 5.8e-29 99.9 0.0 9.5e-29 99.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD99386.1 - 3e-13 49.2 0.0 7.1e-13 48.0 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EGD99386.1 - 9e-13 49.1 0.0 1.4e-12 48.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGD99386.1 - 2.4e-07 31.1 0.0 0.00015 22.0 0.1 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EGD99386.1 - 0.044 13.1 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD PF12710.2 EGD99386.1 - 0.071 13.2 1.2 1.6 8.8 0.8 2.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Mhr1 PF12829.2 EGD99387.1 - 0.026 14.3 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination DUF1746 PF08508.5 EGD99388.1 - 5e-41 139.2 0.4 7.2e-41 138.7 0.3 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CLP_protease PF00574.18 EGD99389.1 - 2.5e-70 235.8 0.0 3.2e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease DHDPS PF00701.17 EGD99389.1 - 0.011 14.4 0.0 0.019 13.6 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Rep_fac_C PF08542.6 EGD99390.1 - 3.6e-12 46.0 0.0 7.3e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EGD99390.1 - 4.3e-12 46.3 0.0 1.3e-11 44.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EGD99390.1 - 9.3e-10 38.3 0.0 6.7e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.10 EGD99390.1 - 1.1e-08 34.3 0.2 1.2e-05 24.1 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EGD99390.1 - 1.1e-05 24.6 0.0 2.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EGD99390.1 - 5.4e-05 22.8 0.0 7.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGD99390.1 - 0.00022 21.3 0.2 0.015 15.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EGD99390.1 - 0.0019 17.1 0.0 0.0039 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EGD99390.1 - 0.0033 17.4 0.2 0.16 11.9 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EGD99390.1 - 0.0041 16.8 0.0 0.015 15.0 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EGD99390.1 - 0.0053 15.7 0.0 0.013 14.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 EGD99390.1 - 0.0053 16.2 0.0 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EGD99390.1 - 0.013 14.6 0.0 0.57 9.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EGD99390.1 - 0.02 14.4 1.6 0.027 14.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EGD99391.1 - 1.2e-42 145.9 51.1 1.2e-42 145.9 35.4 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD99391.1 - 4.2e-11 41.7 16.9 4.2e-11 41.7 11.7 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGD99391.1 - 9e-11 40.9 33.3 3.1e-10 39.2 12.0 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Sec20 PF03908.8 EGD99392.1 - 4.9e-16 58.2 2.8 1.3e-15 56.8 1.9 1.8 1 0 0 1 1 1 1 Sec20 MRP_L53 PF10780.4 EGD99393.1 - 1.5e-12 47.3 0.1 2e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.14 EGD99394.1 - 8.6e-51 171.4 0.1 1.1e-50 171.1 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.12 EGD99395.1 - 1e-41 142.7 0.0 2e-41 141.8 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_M28 PF04389.12 EGD99396.1 - 4.2e-35 121.1 0.0 7.2e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EGD99396.1 - 7.8e-17 60.8 0.2 1.8e-16 59.6 0.2 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 EGD99396.1 - 0.013 14.2 0.0 0.32 9.7 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase SNF2_N PF00176.18 EGD99397.1 - 4.7e-58 196.3 0.1 6.9e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD99397.1 - 2e-15 56.4 0.0 5.3e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD99397.1 - 1.7e-07 31.2 0.0 4.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGD99397.1 - 7.6e-07 28.7 0.0 1.9e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1508 PF07411.7 EGD99398.1 - 0.14 11.6 0.2 0.31 10.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) VIT1 PF01988.14 EGD99400.1 - 9.8 5.5 8.5 0.27 10.7 0.6 2.1 1 1 0 2 2 2 0 VIT family TRAM_LAG1_CLN8 PF03798.11 EGD99401.1 - 3.9e-33 114.6 15.6 7.9e-33 113.6 10.8 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EGD99401.1 - 3.9e-23 80.7 1.9 4.2e-23 80.6 0.1 2.0 2 1 0 2 2 2 1 TRAM1-like protein Hira PF07569.6 EGD99402.1 - 6.3e-77 257.6 0.0 1.4e-76 256.5 0.0 1.6 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 EGD99402.1 - 1e-40 136.1 21.4 1.5e-07 31.0 0.0 9.0 9 0 0 9 9 9 8 WD domain, G-beta repeat HIRA_B PF09453.5 EGD99402.1 - 2.4e-10 39.6 0.1 6.4e-10 38.3 0.1 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EGD99402.1 - 9e-06 25.2 2.6 1.6 8.4 0.0 5.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EGD99402.1 - 0.005 14.7 0.0 0.013 13.3 0.0 1.6 1 0 0 1 1 1 1 IKI3 family TFIIIC_delta PF12657.2 EGD99402.1 - 0.025 14.2 0.9 0.57 9.8 0.4 3.0 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term YchF-GTPase_C PF06071.8 EGD99403.1 - 1.8e-32 110.9 0.2 3.5e-32 110.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EGD99403.1 - 1.2e-12 47.8 0.0 2e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGD99403.1 - 0.00051 19.3 0.0 0.0012 18.1 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EGD99403.1 - 0.0021 17.8 0.0 0.0076 16.0 0.0 2.0 2 1 0 2 2 2 1 TGS domain AAA_14 PF13173.1 EGD99403.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGD99403.1 - 0.04 14.2 0.1 16 5.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EGD99403.1 - 0.087 12.5 0.5 3.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EGD99403.1 - 0.089 12.6 0.1 2.3 8.0 0.0 2.5 1 1 1 3 3 3 0 Dynamin family PUA PF01472.15 EGD99404.1 - 9.4e-14 50.9 0.4 1.4e-13 50.3 0.2 1.3 1 0 0 1 1 1 1 PUA domain RIC1 PF07064.8 EGD99405.1 - 8.3e-79 264.6 0.0 1.2e-78 264.1 0.0 1.2 1 0 0 1 1 1 1 RIC1 TPR_11 PF13414.1 EGD99406.1 - 1.4e-19 69.4 6.1 2.1e-16 59.2 1.5 2.4 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGD99406.1 - 3.7e-13 48.3 6.4 0.00092 18.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGD99406.1 - 4.5e-13 48.1 4.2 0.0001 21.7 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGD99406.1 - 3.5e-10 40.2 17.2 3e-07 30.9 2.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGD99406.1 - 1.2e-07 31.3 0.7 0.0082 16.2 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD99406.1 - 4.6e-06 26.0 0.3 3.1 7.8 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGD99406.1 - 1.4e-05 24.8 3.5 0.017 15.0 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD99406.1 - 2.1e-05 24.7 6.8 0.026 15.1 0.3 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGD99406.1 - 8.1e-05 22.4 2.1 0.00047 19.9 0.3 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat XPC-binding PF09280.6 EGD99406.1 - 0.00014 21.2 5.6 0.00014 21.1 2.7 1.9 2 0 0 2 2 2 1 XPC-binding domain TPR_8 PF13181.1 EGD99406.1 - 0.00019 20.9 2.3 1.3 8.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGD99406.1 - 0.00025 21.3 2.1 0.00072 19.8 0.6 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.12 EGD99406.1 - 0.054 13.8 0.7 1.1 9.5 0.2 2.6 3 0 0 3 3 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 EGD99406.1 - 0.64 10.6 6.6 6.5 7.4 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Tim44 PF04280.10 EGD99407.1 - 5e-34 117.4 0.0 1.3e-33 116.0 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain VPS9 PF02204.13 EGD99409.1 - 3.8e-17 62.2 0.1 9.1e-17 60.9 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 EGD99409.1 - 3.3e-15 55.7 0.6 1.7e-11 43.9 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGD99409.1 - 2.6e-09 37.3 0.0 1.8e-05 25.0 0.0 3.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGD99409.1 - 1.6e-08 33.9 0.1 0.81 10.1 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EGD99409.1 - 1.7e-08 34.7 0.1 0.013 16.0 0.0 5.0 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EGD99409.1 - 4e-06 26.3 0.2 0.044 13.6 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat PX PF00787.19 EGD99409.1 - 1.1e-05 25.1 0.7 1.1e-05 25.1 0.5 1.9 2 0 0 2 2 2 1 PX domain U79_P34 PF03064.11 EGD99410.1 - 0.23 10.9 9.9 0.43 10.0 6.9 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Inhibitor_I78 PF11720.3 EGD99411.1 - 5.7e-16 57.9 0.0 7.3e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EGD99411.1 - 0.00044 20.3 0.1 0.00061 19.8 0.0 1.5 1 1 0 1 1 1 1 Potato inhibitor I family Nefa_Nip30_N PF10187.4 EGD99412.1 - 9.4e-28 96.3 10.4 9.4e-28 96.3 7.2 1.9 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 EGD99412.1 - 0.0073 15.3 1.4 0.009 15.0 0.9 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF2570 PF10828.3 EGD99412.1 - 0.72 9.4 4.0 0.79 9.3 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) CK_II_beta PF01214.13 EGD99414.1 - 2e-73 245.8 0.1 3.1e-73 245.1 0.1 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Nucleoplasmin PF03066.10 EGD99414.1 - 1.3 8.5 10.6 2.4 7.6 7.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin E1-E2_ATPase PF00122.15 EGD99415.1 - 1.8e-46 158.0 3.1 1.8e-46 158.0 2.2 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGD99415.1 - 9.4e-27 94.8 0.3 1.6e-26 94.0 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGD99415.1 - 9.2e-13 48.7 0.0 2.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EGD99415.1 - 1.3e-08 34.8 0.0 3.2e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EGD99415.1 - 1.8e-05 24.4 0.1 0.14 11.7 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.1 EGD99415.1 - 0.0049 17.0 0.1 0.015 15.4 0.1 1.9 1 0 0 1 1 1 1 CoA binding domain Fungal_trans_2 PF11951.3 EGD99416.1 - 7.7e-33 113.6 1.3 1.8e-16 59.7 0.3 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD99416.1 - 3.7e-07 29.9 10.7 8.2e-07 28.8 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 EGD99417.1 - 1.4e-07 31.3 0.3 7.3e-07 28.9 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD99417.1 - 0.00092 18.9 2.7 0.0019 17.9 1.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD99417.1 - 0.00095 19.1 0.8 0.0012 18.7 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGD99417.1 - 0.011 16.0 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF3089 PF11288.3 EGD99417.1 - 0.033 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Chlorophyllase2 PF12740.2 EGD99417.1 - 0.11 11.3 0.1 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme NmrA PF05368.8 EGD99418.1 - 5.6e-12 45.4 0.0 6e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD99418.1 - 1.9e-07 31.2 0.0 2.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EGD99418.1 - 0.00012 21.2 0.0 0.00017 20.7 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EGD99418.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Peptidase_S10 PF00450.17 EGD99419.1 - 1.6e-100 337.2 0.1 4.9e-100 335.5 0.1 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGD99420.1 - 1.2e-25 90.7 0.2 1.9e-25 90.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD99420.1 - 1.2e-25 90.4 0.0 1.8e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD99420.1 - 1.3e-12 47.6 0.0 5.3e-12 45.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EGD99420.1 - 5.1e-05 23.1 0.0 9.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 EGD99420.1 - 6e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase FSH1 PF03959.8 EGD99420.1 - 0.033 13.6 0.0 0.53 9.6 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Esterase PF00756.15 EGD99420.1 - 0.037 13.4 0.1 0.13 11.6 0.0 2.0 1 1 0 1 1 1 0 Putative esterase HemX PF04375.9 EGD99420.1 - 0.049 12.2 0.8 0.07 11.7 0.6 1.1 1 0 0 1 1 1 0 HemX AXE1 PF05448.7 EGD99420.1 - 0.065 11.7 0.0 5.5 5.3 0.0 2.5 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) Ndr PF03096.9 EGD99420.1 - 0.11 10.8 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family PAT1 PF09770.4 EGD99421.1 - 2.5 6.2 21.9 3 5.9 15.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Period_C PF12114.3 EGD99421.1 - 5.3 6.5 14.6 4.6 6.8 3.6 2.2 2 0 0 2 2 2 0 Period protein 2/3C-terminal region DUF605 PF04652.11 EGD99421.1 - 7 5.9 25.3 8.5 5.6 17.5 1.0 1 0 0 1 1 1 0 Vta1 like DUF221 PF02714.10 EGD99422.1 - 8.4e-88 294.3 25.2 3.1e-87 292.4 15.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGD99422.1 - 5.3e-44 149.5 2.5 5.3e-44 149.5 1.7 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EGD99422.1 - 2.6e-30 104.1 0.4 1.4e-28 98.6 0.1 2.6 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EGD99422.1 - 5.8e-15 55.5 0.4 9.7e-15 54.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Rubella_E2 PF05749.6 EGD99422.1 - 0.035 13.3 0.0 0.094 11.9 0.0 1.7 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 zf-C3HC4_3 PF13920.1 EGD99423.1 - 2.4e-05 23.8 9.3 2.4e-05 23.8 6.4 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Tudor-knot PF11717.3 EGD99423.1 - 0.063 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain MutS_V PF00488.16 EGD99424.1 - 1.8e-74 250.1 0.3 2.8e-74 249.4 0.2 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGD99424.1 - 2e-33 115.9 1.1 6.3e-33 114.2 0.8 1.9 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EGD99424.1 - 3.8e-13 49.4 0.4 1.6e-11 44.2 0.1 2.8 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 EGD99424.1 - 1.4e-11 44.5 0.2 5.3e-11 42.7 0.2 2.0 1 0 0 1 1 1 1 MutS domain II AAA_30 PF13604.1 EGD99424.1 - 0.071 12.6 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EGD99425.1 - 1.4e-84 275.2 24.4 9.3e-16 57.0 0.2 8.6 9 0 0 9 9 9 8 WD domain, G-beta repeat Nup160 PF11715.3 EGD99425.1 - 3.1e-08 32.2 7.2 0.035 12.2 0.0 5.6 4 2 0 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EGD99425.1 - 1.1e-07 31.8 0.1 0.069 12.8 0.0 3.8 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.7 EGD99425.1 - 5.6e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 EGD99425.1 - 0.043 13.7 0.1 1.1 9.2 0.0 2.9 3 1 0 3 3 3 0 Siderophore-interacting FAD-binding domain PD40 PF07676.7 EGD99425.1 - 0.059 13.0 0.5 5.9 6.6 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Rav1p_C PF12234.3 EGD99425.1 - 0.12 10.5 0.0 1.7 6.6 0.0 2.4 3 0 0 3 3 3 0 RAVE protein 1 C terminal Sec10 PF07393.6 EGD99426.1 - 1.5e-152 509.3 0.1 1.9e-152 508.9 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EGD99426.1 - 5.7e-05 22.7 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD99426.1 - 6.8e-05 22.4 0.2 0.0002 20.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain RINT1_TIP1 PF04437.8 EGD99426.1 - 0.025 13.1 0.5 0.056 11.9 0.0 1.7 2 0 0 2 2 2 0 RINT-1 / TIP-1 family AAA PF00004.24 EGD99427.1 - 2.4e-31 108.6 0.0 4.9e-31 107.6 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGD99427.1 - 1.7e-06 28.8 0.0 1.4e-05 25.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGD99427.1 - 4.5e-06 26.8 0.0 1.4e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD99427.1 - 6.8e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 EGD99427.1 - 3.8e-05 23.3 0.0 7.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD99427.1 - 7.3e-05 23.0 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGD99427.1 - 8.5e-05 22.0 0.0 0.0012 18.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EGD99427.1 - 0.0001 22.1 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGD99427.1 - 0.00014 21.5 0.0 0.00034 20.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 EGD99427.1 - 0.00028 20.5 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EGD99427.1 - 0.0005 20.2 0.1 0.0015 18.6 0.0 1.9 2 0 0 2 2 1 1 RNA helicase Arch_ATPase PF01637.13 EGD99427.1 - 0.00083 19.1 0.1 0.019 14.6 0.1 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 EGD99427.1 - 0.0014 18.5 0.0 0.0023 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGD99427.1 - 0.0015 17.5 0.1 0.015 14.3 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus UPF0079 PF02367.12 EGD99427.1 - 0.0024 17.4 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EGD99427.1 - 0.0027 17.4 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EGD99427.1 - 0.0076 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EGD99427.1 - 0.008 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGD99427.1 - 0.0095 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EGD99427.1 - 0.0098 15.8 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EGD99427.1 - 0.013 14.6 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EGD99427.1 - 0.029 13.3 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KTI12 PF08433.5 EGD99427.1 - 0.049 12.8 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MobB PF03205.9 EGD99427.1 - 0.05 13.2 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EGD99427.1 - 0.054 12.5 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 EGD99427.1 - 0.055 13.0 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EGD99427.1 - 0.079 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_11 PF13086.1 EGD99427.1 - 0.095 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EGD99427.1 - 0.13 11.2 0.0 0.52 9.2 0.0 1.6 1 1 1 2 2 2 0 KAP family P-loop domain PhoH PF02562.11 EGD99427.1 - 0.16 11.1 0.0 0.9 8.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_13 PF13166.1 EGD99427.1 - 0.19 10.1 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Cytochrom_C1 PF02167.10 EGD99428.1 - 1.3e-80 270.1 0.0 1.8e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family SbcCD_C PF13558.1 EGD99428.1 - 0.0014 18.5 0.2 0.0028 17.5 0.1 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Cytochrome_CBB3 PF13442.1 EGD99428.1 - 0.085 13.0 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AIG2_2 PF13772.1 EGD99429.1 - 2.6e-06 27.4 0.0 2.4e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family Pax2_C PF12403.3 EGD99431.1 - 0.019 14.6 0.3 0.039 13.6 0.2 1.5 1 0 0 1 1 1 0 Paired-box protein 2 C terminal DAHP_synth_1 PF00793.15 EGD99432.1 - 1.3e-99 332.3 0.1 1.6e-99 332.0 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MFS_1 PF07690.11 EGD99433.1 - 1.8e-20 72.9 26.6 1.8e-20 72.9 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2929 PF11151.3 EGD99433.1 - 0.035 14.1 0.7 0.21 11.6 0.5 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2929) DUF221 PF02714.10 EGD99434.1 - 2e-97 325.9 21.1 3.8e-97 325.0 14.6 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGD99434.1 - 2.6e-39 134.3 1.2 2.6e-39 134.3 0.9 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGD99434.1 - 4e-24 84.9 0.8 7.1e-24 84.1 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Anoctamin PF04547.7 EGD99434.1 - 0.00092 17.9 1.5 0.00092 17.9 1.1 2.1 3 0 0 3 3 3 1 Calcium-activated chloride channel hDGE_amylase PF14701.1 EGD99435.1 - 2.2e-133 445.2 0.1 2e-130 435.4 0.0 2.2 1 1 1 2 2 2 2 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EGD99435.1 - 1.1e-116 389.5 0.2 2.2e-116 388.6 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EGD99435.1 - 1.6e-85 286.4 0.0 2.9e-85 285.5 0.0 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EGD99435.1 - 1.7e-26 91.8 0.0 4e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme NAD_Gly3P_dh_N PF01210.18 EGD99436.1 - 4.7e-46 156.3 0.0 7.6e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EGD99436.1 - 4.2e-42 143.3 0.1 7.8e-42 142.5 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Pox_VLTF3 PF04947.9 EGD99436.1 - 0.022 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like SLX9 PF15341.1 EGD99437.1 - 8.1e-37 126.3 3.5 1e-36 126.0 2.4 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 NAD_kinase PF01513.16 EGD99437.1 - 0.017 13.8 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Pilin_PilA PF14245.1 EGD99437.1 - 0.1 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Type IV pilin PilA ThiF PF00899.16 EGD99438.1 - 3.4e-34 117.5 0.1 2.1e-33 115.0 0.1 2.1 1 1 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EGD99438.1 - 1.3e-24 85.5 0.1 2.3e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EGD99438.1 - 1.1e-11 45.0 0.0 2.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EGD99438.1 - 0.0047 17.0 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EGD99438.1 - 0.0091 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FlxA PF14282.1 EGD99438.1 - 0.013 15.3 3.6 0.026 14.4 2.5 1.5 1 0 0 1 1 1 0 FlxA-like protein DAO PF01266.19 EGD99438.1 - 0.015 14.2 0.9 0.019 13.9 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EGD99438.1 - 0.017 15.3 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EGD99438.1 - 0.074 12.0 0.7 0.11 11.5 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain YlqD PF11068.3 EGD99438.1 - 0.11 12.5 1.9 0.2 11.6 1.3 1.3 1 0 0 1 1 1 0 YlqD protein DivIC PF04977.10 EGD99438.1 - 0.28 10.7 3.1 0.49 9.9 2.2 1.3 1 0 0 1 1 1 0 Septum formation initiator HR1 PF02185.11 EGD99438.1 - 0.6 9.8 4.3 1.5 8.6 3.0 1.7 1 0 0 1 1 1 0 Hr1 repeat DPBB_1 PF03330.13 EGD99439.1 - 4.1e-10 39.5 0.1 1.7e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGD99439.1 - 0.075 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Barwin family MARVEL PF01284.18 EGD99439.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain Bac_export_3 PF01313.14 EGD99439.1 - 0.35 10.5 3.6 0.57 9.8 2.5 1.2 1 0 0 1 1 1 0 Bacterial export proteins, family 3 MFS_1 PF07690.11 EGD99440.1 - 0.0051 15.5 0.1 0.0053 15.5 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PMP1_2 PF08114.6 EGD99440.1 - 0.0077 15.6 3.6 0.012 15.0 1.8 1.8 1 1 0 1 1 1 1 ATPase proteolipid family DUF3611 PF12263.3 EGD99440.1 - 0.017 14.5 0.5 0.021 14.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) 5TM-5TMR_LYT PF07694.7 EGD99440.1 - 0.019 14.2 0.9 0.085 12.1 0.1 1.9 2 0 0 2 2 2 0 5TMR of 5TMR-LYT DUF975 PF06161.6 EGD99440.1 - 0.057 13.1 0.1 0.067 12.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF975) NfeD PF01957.13 EGD99440.1 - 0.064 13.4 0.9 0.11 12.6 0.7 1.5 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF202 PF02656.10 EGD99440.1 - 0.064 13.4 2.3 0.15 12.2 1.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Bac_Ubq_Cox PF01654.12 EGD99440.1 - 0.086 11.2 1.5 0.1 10.9 1.0 1.0 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase DUF3487 PF11990.3 EGD99440.1 - 1.5 8.2 5.3 12 5.3 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) NAD_binding_11 PF14833.1 EGD99442.1 - 6.4e-41 139.2 0.8 7.4e-26 90.6 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EGD99442.1 - 2.4e-37 128.2 0.1 4.9e-37 127.2 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EGD99442.1 - 0.00017 21.2 0.1 0.00034 20.3 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGD99442.1 - 0.00078 19.8 0.1 0.004 17.5 0.0 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EGD99442.1 - 0.011 15.1 0.1 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EGD99442.1 - 0.073 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EGD99442.1 - 0.1 11.9 0.1 9.2 5.5 0.0 2.3 1 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F_bP_aldolase PF01116.15 EGD99443.1 - 2.3e-83 279.6 0.0 2.6e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Fer2_3 PF13085.1 EGD99444.1 - 6.3e-32 109.6 0.0 1.1e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EGD99444.1 - 1.1e-09 38.5 5.9 1.1e-09 38.5 4.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EGD99444.1 - 1e-08 35.0 4.2 1e-08 35.0 2.9 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGD99444.1 - 0.00013 22.2 1.0 0.00013 22.2 0.7 2.8 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGD99444.1 - 0.00039 20.1 3.0 0.00039 20.1 2.1 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGD99444.1 - 0.00067 19.8 4.2 0.038 14.2 0.3 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EGD99444.1 - 0.0025 18.1 4.4 0.0025 18.1 3.1 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EGD99444.1 - 0.0042 16.8 0.3 0.0042 16.8 0.2 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain RTA1 PF04479.8 EGD99445.1 - 1.2e-49 168.8 4.5 1.6e-49 168.4 3.1 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2636 PF11120.3 EGD99445.1 - 0.2 11.2 1.7 0.21 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Velvet PF11754.3 EGD99447.1 - 1.5e-73 246.7 0.0 1.5e-73 246.7 0.0 1.7 2 0 0 2 2 2 1 Velvet factor TFIIA PF03153.8 EGD99447.1 - 3.2 7.5 22.4 1.1 9.0 1.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Git3 PF11710.3 EGD99448.1 - 1.4e-27 96.5 7.7 2.8e-27 95.5 5.4 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EGD99448.1 - 1.2e-09 37.8 1.3 3.6e-09 36.2 0.0 2.4 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EGD99448.1 - 4.3e-08 32.6 4.6 4.3e-08 32.6 3.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EGD99448.1 - 0.0012 17.7 6.9 0.0019 17.1 4.8 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor GPDPase_memb PF10110.4 EGD99448.1 - 0.08 12.3 2.6 0.085 12.2 0.3 2.1 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Podoplanin PF05808.6 EGD99449.1 - 1.4 8.4 0.0 1.4 8.4 0.0 3.5 3 1 0 3 3 3 0 Podoplanin UPF0370 PF13980.1 EGD99450.1 - 0.022 14.5 2.1 0.4 10.5 0.9 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) DnaJ_CXXCXGXG PF00684.14 EGD99451.1 - 0.0064 16.5 5.1 3.3 7.8 0.1 3.1 3 0 0 3 3 3 2 DnaJ central domain zf-TFIIB PF13453.1 EGD99451.1 - 0.84 8.8 7.2 7 5.9 0.6 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger HhH-GPD PF00730.20 EGD99452.1 - 7.2e-09 35.9 0.0 7.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4332 PF14229.1 EGD99452.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Fasciclin PF02469.17 EGD99453.1 - 3.4e-33 114.3 0.0 3e-18 66.0 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain G_glu_transpept PF01019.16 EGD99454.1 - 2.6e-160 534.2 0.0 3e-160 534.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase AAA PF00004.24 EGD99456.1 - 1.7e-45 154.4 0.1 6.5e-45 152.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGD99456.1 - 3.7e-09 36.4 0.1 1.1e-08 34.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGD99456.1 - 4.4e-08 33.2 0.0 9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGD99456.1 - 4.1e-07 30.1 0.0 1.5e-06 28.3 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EGD99456.1 - 8.5e-07 29.1 0.6 0.001 19.2 0.0 2.7 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 EGD99456.1 - 2.9e-06 26.3 0.0 5e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EGD99456.1 - 7.2e-05 22.7 0.0 0.00087 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGD99456.1 - 0.00025 20.1 0.1 0.0008 18.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGD99456.1 - 0.00026 20.9 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD99456.1 - 0.00057 20.7 0.0 0.0019 19.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EGD99456.1 - 0.00072 19.2 0.3 0.056 13.1 0.0 2.9 3 0 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 EGD99456.1 - 0.0011 18.1 0.1 0.0037 16.3 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EGD99456.1 - 0.0014 18.3 0.2 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EGD99456.1 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EGD99456.1 - 0.0021 16.8 0.0 0.0037 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 EGD99456.1 - 0.0029 17.3 0.0 0.0091 15.7 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 EGD99456.1 - 0.0037 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EGD99456.1 - 0.0043 16.6 0.0 0.038 13.6 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EGD99456.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGD99456.1 - 0.0061 15.7 0.0 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EGD99456.1 - 0.0064 16.0 0.5 0.018 14.6 0.0 1.9 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.1 EGD99456.1 - 0.0087 15.6 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EGD99456.1 - 0.0089 15.7 0.1 0.059 13.0 0.0 2.2 1 1 1 2 2 2 1 Archaeal ATPase IstB_IS21 PF01695.12 EGD99456.1 - 0.0094 15.3 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EGD99456.1 - 0.012 15.0 2.2 0.074 12.4 0.1 2.6 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.1 EGD99456.1 - 0.013 15.0 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 EGD99456.1 - 0.019 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 EGD99456.1 - 0.025 13.7 0.4 0.45 9.5 0.0 2.4 3 0 0 3 3 2 0 KaiC AAA_18 PF13238.1 EGD99456.1 - 0.028 14.7 0.1 0.097 12.9 0.0 2.0 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 EGD99456.1 - 0.045 13.2 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 EGD99456.1 - 0.057 13.7 0.1 0.81 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 EGD99456.1 - 0.063 12.0 0.2 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activ_2 PF14532.1 EGD99456.1 - 0.093 12.7 0.0 0.3 11.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EGD99456.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 EGD99456.1 - 0.16 11.5 0.0 0.46 10.0 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.12 EGD99456.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.18 EGD99457.1 - 1.6e-108 362.6 0.6 2e-108 362.4 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGD99457.1 - 2.2e-11 43.9 0.3 1.2e-10 41.6 0.1 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGD99457.1 - 1.7e-06 28.4 0.3 0.021 15.3 0.0 3.3 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EGD99457.1 - 5.7e-06 25.9 0.0 7.4e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal NIF PF03031.13 EGD99458.1 - 7.3e-28 97.2 0.1 1.4e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EGD99458.1 - 2.8e-12 46.2 0.2 5.8e-12 45.2 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EGD99458.1 - 6.1e-10 39.1 0.0 2.8e-09 36.9 0.0 2.2 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl_2 PF13533.1 EGD99458.1 - 0.022 14.4 0.0 5.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Biotin-lipoyl like MARVEL PF01284.18 EGD99460.1 - 0.00021 21.1 15.9 0.00035 20.3 10.9 1.5 1 1 0 1 1 1 1 Membrane-associating domain Arginase PF00491.16 EGD99461.1 - 4e-77 259.2 0.7 4.6e-77 259.0 0.5 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.10 EGD99462.1 - 2.3e-97 325.3 0.0 3e-97 324.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EGD99462.1 - 9.7e-24 83.7 0.0 1.6e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 GatB domain DUF4484 PF14831.1 EGD99463.1 - 1.2 9.2 5.0 5.1 7.1 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4484) ECH PF00378.15 EGD99466.1 - 6.6e-50 169.5 0.0 8.2e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pox_P21 PF05313.7 EGD99466.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein AAA_16 PF13191.1 EGD99467.1 - 7.9e-07 29.2 0.8 4.9e-05 23.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EGD99467.1 - 1.7e-05 23.8 0.0 2.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain PGAP1 PF07819.8 EGD99467.1 - 0.0001 21.9 0.1 0.00049 19.7 0.1 2.0 1 1 1 2 2 2 1 PGAP1-like protein AAA_22 PF13401.1 EGD99467.1 - 0.00035 20.7 0.0 0.0013 18.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.9 EGD99467.1 - 0.00054 19.3 0.2 0.0011 18.2 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EGD99467.1 - 0.0022 17.8 1.9 0.019 14.8 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family AAA_33 PF13671.1 EGD99467.1 - 0.0055 16.5 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD99467.1 - 0.0057 15.7 0.0 0.0057 15.7 0.0 1.9 3 0 0 3 3 2 1 Zeta toxin AAA_17 PF13207.1 EGD99467.1 - 0.018 15.8 0.0 0.048 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGD99467.1 - 0.081 12.0 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EGD99467.1 - 0.084 12.5 0.0 0.69 9.5 0.0 2.4 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EGD99467.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain YcxB PF14317.1 EGD99467.1 - 0.22 10.7 0.1 0.62 9.3 0.1 1.8 1 0 0 1 1 1 0 YcxB-like protein DUF883 PF05957.8 EGD99469.1 - 0.25 11.7 5.7 0.53 10.7 3.9 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FHA PF00498.21 EGD99470.1 - 5.4e-12 45.6 0.0 1.2e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain MFS_1 PF07690.11 EGD99471.1 - 4.9e-30 104.4 31.3 4.9e-30 104.4 21.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EGD99472.1 - 1.2e-32 113.0 2.9 1.5e-32 112.6 2.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ PF00226.26 EGD99473.1 - 8.5e-08 31.8 0.1 1.7e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_3 PF07859.8 EGD99474.1 - 7e-36 123.7 0.0 1.6e-34 119.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGD99474.1 - 0.00039 19.1 0.6 0.003 16.2 0.4 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) DUF89 PF01937.14 EGD99474.1 - 0.049 12.4 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 CAP_N PF01213.14 EGD99478.1 - 8.2 5.6 12.6 20 4.3 8.7 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HMG_box PF00505.14 EGD99479.1 - 1.2e-24 86.3 0.5 1.8e-24 85.7 0.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGD99479.1 - 2.5e-19 69.4 0.9 3.6e-19 68.9 0.6 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EGD99479.1 - 0.00065 19.4 0.4 0.00065 19.4 0.3 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 EGD99479.1 - 0.0016 18.6 0.9 0.0042 17.2 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) Bac_luciferase PF00296.15 EGD99479.1 - 0.078 12.0 0.6 0.088 11.9 0.4 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase p450 PF00067.17 EGD99480.1 - 1.2e-23 83.4 0.0 3e-23 82.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Homoserine_dh PF00742.14 EGD99481.1 - 5.8e-51 172.6 0.0 7.6e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EGD99481.1 - 4.5e-11 43.1 0.0 9.6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.1 EGD99482.1 - 4e-06 26.8 0.1 4e-06 26.8 0.1 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4078) HTH_Tnp_Tc3_2 PF01498.13 EGD99483.1 - 1.5e-13 50.6 0.2 3e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EGD99483.1 - 6.5e-08 32.7 0.2 4.1e-07 30.1 0.0 2.1 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EGD99483.1 - 8.4e-05 22.0 0.6 0.00018 21.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EGD99483.1 - 9.1e-05 22.3 0.2 0.00034 20.5 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EGD99483.1 - 0.0002 20.7 0.1 0.42 10.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_7 PF02796.10 EGD99483.1 - 0.00069 19.4 0.2 0.032 14.0 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_Tnp_IS630 PF01710.11 EGD99483.1 - 0.0066 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.1 EGD99483.1 - 0.012 15.1 0.2 0.12 11.9 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain Terminase_5 PF06056.7 EGD99483.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) ATG11 PF10377.4 EGD99484.1 - 1e-40 138.6 2.1 2.2e-40 137.5 0.0 2.9 3 0 0 3 3 3 1 Autophagy-related protein 11 APG17 PF04108.7 EGD99484.1 - 5.4e-08 32.0 0.1 5.4e-08 32.0 0.0 5.0 3 2 0 4 4 4 1 Autophagy protein Apg17 AAA_13 PF13166.1 EGD99484.1 - 3.6e-05 22.4 18.1 3.6e-05 22.4 12.6 4.7 2 1 2 4 4 4 3 AAA domain ERM PF00769.14 EGD99484.1 - 0.0024 17.4 12.4 0.0024 17.4 8.6 6.3 6 3 0 6 6 6 1 Ezrin/radixin/moesin family Lipoprotein_3 PF00938.12 EGD99484.1 - 0.81 9.5 7.1 0.1 12.3 0.3 2.9 3 0 0 3 3 3 0 Lipoprotein CENP-F_leu_zip PF10473.4 EGD99484.1 - 3.4 7.5 80.3 0.071 12.9 15.2 7.2 6 1 1 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 EGD99484.1 - 5.2 6.8 49.0 0.025 14.3 4.6 7.0 6 2 2 8 8 8 0 Laminin Domain II CENP-H PF05837.7 EGD99485.1 - 3.5e-22 78.5 8.9 3.5e-22 78.5 6.2 2.2 2 0 0 2 2 2 1 Centromere protein H (CENP-H) IncA PF04156.9 EGD99485.1 - 1.2 8.7 18.9 0.11 12.0 4.5 2.2 2 0 0 2 2 2 0 IncA protein AAA_11 PF13086.1 EGD99485.1 - 3.9 6.9 7.2 5.5 6.5 4.9 1.3 1 1 0 1 1 1 0 AAA domain DUF4591 PF15261.1 EGD99486.1 - 0.0035 17.6 0.3 0.0065 16.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4591) Pex19 PF04614.7 EGD99487.1 - 4e-60 203.5 24.2 4e-60 203.5 16.8 2.1 1 1 1 2 2 2 1 Pex19 protein family DUF4327 PF14217.1 EGD99487.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4327) Gluconate_2-dh3 PF13618.1 EGD99487.1 - 0.04 14.0 10.2 1.2 9.3 1.4 3.4 2 2 1 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 ASF1_hist_chap PF04729.8 EGD99488.1 - 4.4e-68 227.7 0.0 7.1e-68 227.0 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF4407 PF14362.1 EGD99488.1 - 0.27 10.1 3.7 0.36 9.7 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop14 PF04147.7 EGD99488.1 - 9.2 4.0 25.2 12 3.6 17.5 1.1 1 0 0 1 1 1 0 Nop14-like family Suf PF05843.9 EGD99489.1 - 7.1e-89 298.2 0.0 7.1e-89 298.2 0.0 3.7 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EGD99489.1 - 0.00016 22.0 0.0 0.064 13.9 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat HAT PF02184.11 EGD99489.1 - 0.00027 20.5 0.0 0.0011 18.6 0.0 2.1 1 0 0 1 1 1 1 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 EGD99489.1 - 0.0039 17.8 0.0 0.35 11.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Plasmodium_Vir PF05795.6 EGD99489.1 - 0.19 10.9 0.0 0.4 9.8 0.0 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Oxysterol_BP PF01237.13 EGD99490.1 - 5.1e-88 294.9 0.0 6.4e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Kinesin-relat_1 PF12711.2 EGD99490.1 - 0.012 15.9 0.2 0.038 14.3 0.0 1.8 2 0 0 2 2 2 0 Kinesin motor RTA1 PF04479.8 EGD99491.1 - 3.4e-30 105.1 5.9 5.8e-30 104.4 4.1 1.3 1 0 0 1 1 1 1 RTA1 like protein CUE PF02845.11 EGD99492.1 - 2e-10 39.9 0.0 3.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain ELK PF03789.8 EGD99492.1 - 0.024 14.4 0.2 0.045 13.5 0.2 1.3 1 0 0 1 1 1 0 ELK domain HIRAN PF08797.6 EGD99492.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 HIRAN domain DUF4199 PF13858.1 EGD99492.1 - 1.6 8.6 2.0 3.5 7.5 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2866 PF11065.3 EGD99493.1 - 0.071 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) PCNP PF15473.1 EGD99494.1 - 0.12 12.7 2.9 0.32 11.2 2.3 1.4 2 0 0 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family Spp-24 PF07448.6 EGD99494.1 - 0.2 11.6 0.1 0.2 11.6 0.0 2.1 1 1 1 2 2 2 0 Secreted phosphoprotein 24 (Spp-24) DUF3446 PF11928.3 EGD99494.1 - 1 9.5 19.4 2.1 8.5 13.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Phosphoprotein PF00922.12 EGD99494.1 - 2.2 7.4 8.1 2.6 7.2 5.6 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Asp-B-Hydro_N PF05279.6 EGD99495.1 - 3.8 7.2 23.7 5 6.8 16.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SOBP PF15279.1 EGD99495.1 - 5.1 7.3 16.5 6.1 7.1 11.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CDC27 PF09507.5 EGD99495.1 - 6.4 5.8 39.2 8.8 5.4 27.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Glypican PF01153.14 EGD99495.1 - 10 4.6 9.0 14 4.1 6.3 1.2 1 0 0 1 1 1 0 Glypican UCH PF00443.24 EGD99496.1 - 4.7e-40 137.4 0.0 2.9e-33 115.1 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD99496.1 - 3.1e-11 43.2 0.8 1.2e-09 38.1 0.6 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rubredoxin PF00301.15 EGD99496.1 - 0.15 11.9 0.8 2.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin DUF605 PF04652.11 EGD99496.1 - 0.19 11.0 17.8 0.29 10.5 12.3 1.2 1 0 0 1 1 1 0 Vta1 like zinc_ribbon_4 PF13717.1 EGD99496.1 - 0.78 9.4 8.0 10 5.9 1.6 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGD99496.1 - 0.87 9.2 7.2 9.4 5.9 1.5 2.9 3 0 0 3 3 3 0 zinc-ribbon domain F_bP_aldolase PF01116.15 EGD99498.1 - 3.3e-97 325.0 0.0 3.7e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Tankyrase_bdg_C PF15327.1 EGD99499.1 - 0.00099 19.3 5.0 0.0013 18.9 3.5 1.2 1 0 0 1 1 1 1 Tankyrase binding protein C terminal domain SMN PF06003.7 EGD99499.1 - 0.12 11.5 1.3 0.12 11.4 0.9 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) FCP1_C PF09309.5 EGD99499.1 - 0.15 11.3 11.7 0.19 10.9 8.1 1.2 1 0 0 1 1 1 0 FCP1, C-terminal XAP5 PF04921.9 EGD99499.1 - 0.17 11.4 7.0 0.21 11.1 4.9 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator CDC45 PF02724.9 EGD99499.1 - 0.18 9.8 8.3 0.2 9.6 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.7 EGD99499.1 - 0.71 7.8 5.9 0.79 7.7 4.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Med17 PF10156.4 EGD99499.1 - 0.95 7.6 4.4 0.91 7.7 3.1 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex PBP1_TM PF14812.1 EGD99499.1 - 1.2 9.5 11.9 1.4 9.3 5.4 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Prog_receptor PF02161.10 EGD99499.1 - 1.4 7.6 7.9 1.7 7.4 5.5 1.1 1 0 0 1 1 1 0 Progesterone receptor Stm1_N PF09598.5 EGD99499.1 - 4.9 7.9 9.2 8.8 7.1 6.4 1.6 1 1 0 1 1 1 0 Stm1 TBX PF12598.3 EGD99499.1 - 5.2 7.5 16.3 0.95 9.8 8.0 1.8 2 0 0 2 2 2 0 T-box transcription factor Vfa1 PF08432.5 EGD99499.1 - 5.9 6.8 11.0 1.1 9.2 4.7 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 EGD99499.1 - 6.2 4.3 5.8 5.4 4.5 4.0 1.1 1 0 0 1 1 1 0 Ycf1 RNA_pol_Rpc4 PF05132.9 EGD99499.1 - 7.8 6.4 9.4 3.7 7.5 4.1 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 Prothymosin PF03247.9 EGD99499.1 - 9.8 6.3 27.9 17 5.6 14.7 2.0 2 0 0 2 2 2 0 Prothymosin/parathymosin family DUF221 PF02714.10 EGD99500.1 - 1.1e-91 307.0 20.5 1.6e-91 306.5 14.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGD99500.1 - 5.2e-39 133.3 0.6 5.2e-39 133.3 0.4 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGD99500.1 - 8.8e-17 61.4 0.0 1.9e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3445 PF11927.3 EGD99503.1 - 4.4e-80 268.6 0.0 5.4e-80 268.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Mid2 PF04478.7 EGD99504.1 - 3.6e-05 23.2 0.1 6.8e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4366 PF14283.1 EGD99504.1 - 0.0082 15.5 0.0 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) SKG6 PF08693.5 EGD99504.1 - 0.022 14.0 0.9 0.068 12.4 0.7 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ilm1 PF10311.4 EGD99504.1 - 0.098 12.1 0.3 0.14 11.6 0.2 1.2 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 EphA2_TM PF14575.1 EGD99504.1 - 0.11 12.9 0.9 0.44 10.9 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Menin PF05053.8 EGD99504.1 - 5.6 5.0 6.7 7.1 4.6 4.7 1.1 1 0 0 1 1 1 0 Menin EXS PF03124.9 EGD99505.1 - 1.3e-94 317.1 33.7 1.6e-94 316.7 23.4 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EGD99505.1 - 1.3e-41 143.2 0.2 1.7e-41 142.8 0.2 1.1 1 0 0 1 1 1 1 SPX domain HAD_2 PF13419.1 EGD99506.1 - 5.3e-10 39.7 0.0 1.4e-09 38.4 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGD99506.1 - 3.3e-08 34.2 0.0 1.5e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD99506.1 - 1.8e-07 30.7 0.0 6.5e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 HAD-hyrolase-like Abhydrolase_5 PF12695.2 EGD99507.1 - 2.1e-07 30.7 0.0 4.3e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EGD99507.1 - 0.00063 18.4 0.0 0.0014 17.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.6 EGD99507.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Zn_clus PF00172.13 EGD99508.1 - 1.6e-09 37.5 10.5 2.8e-09 36.7 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGD99508.1 - 0.015 13.9 1.3 0.019 13.5 0.9 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Multi_ubiq PF14452.1 EGD99508.1 - 0.083 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Multiubiquitin Abhydrolase_2 PF02230.11 EGD99509.1 - 3.4e-21 75.6 0.0 4.3e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGD99509.1 - 9.7e-09 35.4 0.1 1.2e-08 35.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD99509.1 - 1.3e-05 25.0 0.1 1.9e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family KfrA_N PF11740.3 EGD99510.1 - 0.0015 19.0 0.4 0.23 11.9 0.1 2.7 2 0 0 2 2 2 1 Plasmid replication region DNA-binding N-term PDEase_I_N PF08499.7 EGD99510.1 - 0.0024 17.7 0.4 0.089 12.6 0.1 2.5 1 1 1 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal UPF0118 PF01594.11 EGD99510.1 - 0.061 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF20 Metallophos PF00149.23 EGD99511.1 - 1.1e-40 139.2 1.3 1.8e-40 138.5 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HSP70 PF00012.15 EGD99513.1 - 8.3e-07 27.3 0.0 1.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein Phage_GP20 PF06810.6 EGD99514.1 - 0.029 13.7 1.4 0.049 13.0 1.0 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 P22_AR_C PF10548.4 EGD99514.1 - 0.086 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P22AR C-terminal domain Voldacs PF03517.8 EGD99515.1 - 3.6e-08 33.3 3.2 3.6e-08 33.3 2.2 1.9 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling LIP PF03583.9 EGD99517.1 - 7.9e-75 251.7 0.0 1e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Opi1 PF08618.5 EGD99520.1 - 1.4e-89 301.0 7.7 5.1e-53 180.5 2.5 3.7 2 1 2 4 4 4 3 Transcription factor Opi1 RdRP PF05183.7 EGD99521.1 - 1.5e-135 453.1 0.0 2e-135 452.7 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AA_permease PF00324.16 EGD99522.1 - 1.1e-123 413.1 41.7 1.3e-123 412.8 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD99522.1 - 8.2e-36 123.4 43.2 9.9e-36 123.1 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease Gtr1_RagA PF04670.7 EGD99524.1 - 7.6e-91 303.3 0.1 9.3e-91 303.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EGD99524.1 - 6.5e-08 32.0 0.0 9.9e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGD99524.1 - 2.1e-07 30.4 0.0 3.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD99524.1 - 6.7e-06 26.6 0.0 1.5e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGD99524.1 - 8.4e-06 25.7 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EGD99524.1 - 0.0017 17.8 0.5 0.0053 16.2 0.2 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EGD99524.1 - 0.0023 17.4 0.0 0.0042 16.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF815 PF05673.8 EGD99524.1 - 0.012 14.5 0.1 0.021 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EGD99524.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NikR_C PF08753.6 EGD99524.1 - 0.055 13.3 0.2 7.2 6.5 0.0 2.6 2 0 0 2 2 2 0 NikR C terminal nickel binding domain DUF258 PF03193.11 EGD99524.1 - 0.065 12.4 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EGD99524.1 - 0.12 11.7 0.2 0.31 10.4 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain AIG1 PF04548.11 EGD99524.1 - 0.27 10.2 1.0 0.41 9.7 0.3 1.9 2 1 0 2 2 2 0 AIG1 family G-alpha PF00503.15 EGD99524.1 - 0.58 8.7 3.4 1.8 7.1 1.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit zf-RanBP PF00641.13 EGD99526.1 - 2e-19 68.3 8.4 6.6e-10 37.9 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RNase_T PF00929.19 EGD99526.1 - 2.1e-07 31.3 0.0 3.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.17 EGD99526.1 - 2.9e-07 30.0 0.0 7.2e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD99526.1 - 4.9e-05 23.2 0.0 0.00037 20.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HasA PF06438.7 EGD99526.1 - 0.12 11.7 1.3 0.2 11.0 0.9 1.3 1 0 0 1 1 1 0 Heme-binding protein A (HasA) DZR PF12773.2 EGD99526.1 - 3.8 7.4 9.5 0.92 9.3 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon Cnd3 PF12719.2 EGD99527.1 - 1.8e-95 319.3 0.0 1e-94 316.9 0.0 2.1 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EGD99527.1 - 5.9e-11 42.4 4.7 1.3e-06 28.6 0.1 4.5 2 2 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 EGD99527.1 - 5e-06 26.8 5.0 0.063 13.7 0.1 5.1 4 1 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EGD99527.1 - 2.5e-05 23.9 5.1 0.1 12.7 0.0 5.8 7 0 0 7 7 7 1 HEAT repeat MMS19_N PF14500.1 EGD99527.1 - 0.033 13.4 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II RICTOR_N PF14664.1 EGD99527.1 - 0.041 12.4 0.6 0.67 8.4 0.1 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term PALP PF00291.20 EGD99528.1 - 1.8e-61 208.0 0.1 2.2e-61 207.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Oxidored_molyb PF00174.14 EGD99529.1 - 1.7e-53 180.4 0.0 2.4e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EGD99529.1 - 1.9e-29 101.9 1.0 4.6e-29 100.7 0.7 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_3_4 PF13754.1 EGD99529.1 - 0.061 13.6 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) BNR PF02012.15 EGD99529.1 - 0.11 12.4 1.7 0.48 10.4 0.2 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat Tim17 PF02466.14 EGD99530.1 - 1.6e-50 170.4 6.3 2.3e-50 169.9 4.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.1 EGD99530.1 - 0.018 14.6 4.9 0.018 14.6 3.4 2.6 3 0 0 3 3 3 0 Glycine zipper Gly-zipper_OmpA PF13436.1 EGD99530.1 - 0.085 12.5 6.3 0.96 9.1 2.1 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 EGD99530.1 - 5.9 7.0 17.2 17 5.6 8.9 2.8 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF4048 PF13257.1 EGD99531.1 - 3.6e-83 279.1 18.5 3.6e-83 279.1 12.8 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4048) CAP59_mtransfer PF11735.3 EGD99532.1 - 2.1e-72 243.2 0.0 2.9e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF4131 PF13567.1 EGD99532.1 - 0.059 12.7 0.3 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RicinB_lectin_2 PF14200.1 EGD99535.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like DUF3108 PF11306.3 EGD99535.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) Phage_terminase PF10668.4 EGD99537.1 - 0.096 12.4 0.1 0.096 12.4 0.0 1.8 2 0 0 2 2 2 0 Phage terminase small subunit Pkinase PF00069.20 EGD99538.1 - 5.2e-72 242.1 0.0 7.4e-72 241.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD99538.1 - 4.7e-48 163.5 0.0 7.2e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD99538.1 - 1.7e-05 23.9 0.0 0.00016 20.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGD99538.1 - 0.042 13.5 0.0 5.4 6.6 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family FAD-oxidase_C PF02913.14 EGD99539.1 - 2.3e-60 204.0 0.0 3.3e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGD99539.1 - 1.7e-35 121.4 0.3 3.3e-35 120.5 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.16 EGD99540.1 - 5.4e-59 199.3 0.0 6.7e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_M19 PF01244.16 EGD99540.1 - 0.11 11.4 0.0 0.69 8.7 0.0 2.0 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) Proteasome PF00227.21 EGD99541.1 - 4.2e-52 176.2 0.1 5.4e-52 175.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGD99541.1 - 1.2e-07 30.8 1.5 1.4e-07 30.6 0.0 2.0 2 1 0 2 2 2 1 Proteasome subunit A N-terminal signature TRIQK PF15168.1 EGD99542.1 - 0.16 11.9 0.1 0.18 11.7 0.1 1.2 1 1 0 1 1 1 0 Triple QxxK/R motif-containing protein family ERG4_ERG24 PF01222.12 EGD99543.1 - 6.1e-148 492.9 9.8 6.9e-148 492.7 6.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGD99543.1 - 5e-05 22.7 0.1 0.00015 21.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Exo_endo_phos PF03372.18 EGD99544.1 - 5.8e-24 85.3 0.0 1.2e-23 84.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.1 EGD99544.1 - 0.11 12.2 0.1 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EGD99544.1 - 3.9 7.8 5.6 8 6.8 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain FMO-like PF00743.14 EGD99545.1 - 4.4e-18 64.7 0.3 3.8e-16 58.3 0.0 3.0 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGD99545.1 - 1.4e-17 64.3 0.0 4.7e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD99545.1 - 4.4e-06 25.8 0.0 0.00021 20.3 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGD99545.1 - 0.002 18.1 1.2 0.0033 17.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGD99545.1 - 0.018 14.9 0.0 1.1 9.0 0.0 2.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD99545.1 - 0.075 12.8 0.0 1.2 8.8 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding APH PF01636.18 EGD99546.1 - 6.2e-20 71.9 0.0 8.4e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD99546.1 - 1.2e-06 28.2 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGD99546.1 - 0.00056 19.1 0.0 0.06 12.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.17 EGD99546.1 - 0.0021 17.4 0.0 0.076 12.3 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.9 EGD99546.1 - 0.0047 15.9 0.1 0.11 11.4 0.0 2.1 2 0 0 2 2 2 1 Fructosamine kinase Kdo PF06293.9 EGD99546.1 - 0.015 14.3 0.0 0.51 9.3 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EGD99546.1 - 0.063 12.3 0.0 0.63 9.0 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase DUF1679 PF07914.6 EGD99546.1 - 0.14 10.8 0.0 0.47 9.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 EGD99546.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase UPF0047 PF01894.12 EGD99548.1 - 2.1e-42 143.6 0.0 2.4e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 GFA PF04828.9 EGD99549.1 - 6.9e-06 25.9 3.1 0.00018 21.3 2.2 2.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ECH PF00378.15 EGD99550.1 - 3.2e-47 160.7 0.0 4e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EGD99550.1 - 0.031 14.0 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 zf-CHCC PF10276.4 EGD99551.1 - 7.5e-16 57.6 1.9 1.2e-15 57.0 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger domain MPP6 PF10175.4 EGD99552.1 - 0.092 13.1 0.7 22 5.5 0.0 3.0 2 1 1 3 3 3 0 M-phase phosphoprotein 6 CoaE PF01121.15 EGD99553.1 - 4.3e-43 146.8 0.0 5.9e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EGD99553.1 - 0.00021 22.0 0.0 0.0006 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD99553.1 - 0.062 13.6 0.2 0.26 11.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain 2TM PF13239.1 EGD99553.1 - 0.064 13.3 0.2 0.064 13.3 0.2 1.7 2 0 0 2 2 2 0 2TM domain NUDIX_2 PF13869.1 EGD99554.1 - 3.5e-61 205.8 0.0 1.9e-46 157.7 0.0 2.1 1 1 1 2 2 2 2 Nucleotide hydrolase DUF4316 PF14195.1 EGD99554.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) APH PF01636.18 EGD99555.1 - 6.5e-12 45.6 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD99555.1 - 0.077 12.5 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_M16_C PF05193.16 EGD99556.1 - 2.8e-34 118.4 0.2 9.2e-23 80.8 0.0 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGD99556.1 - 3.9e-32 111.0 2.7 4.1e-21 75.2 0.2 4.3 4 0 0 4 4 4 2 Insulinase (Peptidase family M16) MFS_1 PF07690.11 EGD99559.1 - 1.4e-33 116.0 39.1 1.4e-33 116.0 27.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD99560.1 - 5.9e-94 315.1 18.3 8e-88 294.9 7.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGD99560.1 - 5.3e-19 68.1 20.6 2.6e-18 65.8 11.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD99560.1 - 0.008 14.4 1.5 0.0086 14.3 0.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TPR_19 PF14559.1 EGD99560.1 - 0.027 14.8 0.1 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_3 PF05977.8 EGD99560.1 - 0.033 12.2 2.2 0.043 11.9 1.0 1.4 1 1 0 1 1 1 0 Transmembrane secretion effector Hist_deacetyl PF00850.14 EGD99561.1 - 3.1e-94 315.7 0.1 2.1e-93 313.0 0.0 2.0 1 1 1 2 2 2 1 Histone deacetylase domain Arb2 PF09757.4 EGD99561.1 - 5.2e-49 166.0 0.7 8.5e-49 165.3 0.5 1.4 1 0 0 1 1 1 1 Arb2 domain WzyE PF06899.6 EGD99561.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 WzyE protein Gp_dh_C PF02800.15 EGD99562.1 - 3.1e-74 247.6 0.0 5.2e-74 246.9 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EGD99562.1 - 1.7e-59 200.1 0.2 3.3e-59 199.1 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EGD99562.1 - 0.0022 17.8 0.0 0.0072 16.2 0.0 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EGD99562.1 - 0.029 14.8 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.14 EGD99562.1 - 0.1 11.7 0.0 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pho88 PF10032.4 EGD99564.1 - 4e-78 261.0 0.8 4.6e-78 260.8 0.5 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF2576 PF10845.3 EGD99564.1 - 0.061 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Histone PF00125.19 EGD99565.1 - 1.3e-21 76.5 0.1 1.6e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGD99565.1 - 0.00043 20.2 0.0 0.00061 19.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HSF_DNA-bind PF00447.12 EGD99567.1 - 6.4e-30 103.3 0.3 1.6e-29 102.0 0.2 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 EGD99567.1 - 0.058 13.1 0.1 0.058 13.1 0.1 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding R3H PF01424.17 EGD99570.1 - 3.4e-10 39.4 0.0 7.6e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EGD99570.1 - 1.2e-06 28.4 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD99570.1 - 1.8e-05 24.2 0.1 3.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD99570.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 EGD99571.1 - 2.4e-37 128.5 0.0 3.8e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.1 EGD99571.1 - 0.033 14.4 0.3 0.033 14.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Lin-8 PF03353.10 EGD99571.1 - 0.044 13.0 2.6 0.064 12.5 1.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist XAP5 PF04921.9 EGD99571.1 - 0.16 11.5 1.4 0.23 10.9 1.0 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator His_Phos_2 PF00328.17 EGD99572.1 - 1.8e-13 50.5 0.0 1.2e-11 44.6 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Peptidase_M19 PF01244.16 EGD99573.1 - 3.3e-103 344.9 0.0 3.8e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) AAA PF00004.24 EGD99574.1 - 2.2e-16 60.2 0.3 4.3e-16 59.3 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EGD99574.1 - 5.1e-15 55.2 0.1 1.3e-14 53.9 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGD99574.1 - 1.8e-13 50.4 0.0 5.3e-13 48.9 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EGD99574.1 - 3.9e-11 42.3 0.0 4.8e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EGD99574.1 - 5.4e-07 29.8 0.2 2.2e-05 24.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGD99574.1 - 1.6e-06 27.7 0.0 4.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EGD99574.1 - 2.2e-06 27.7 0.1 0.00013 21.9 0.0 2.7 3 1 0 4 4 3 1 AAA ATPase domain DNA_pol3_delta PF06144.8 EGD99574.1 - 4.5e-06 26.2 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit TIP49 PF06068.8 EGD99574.1 - 5.8e-06 25.2 0.0 0.017 13.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus RuvB_N PF05496.7 EGD99574.1 - 5.9e-06 25.5 0.1 6.3e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 EGD99574.1 - 1.4e-05 24.7 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGD99574.1 - 1.4e-05 24.8 0.1 5.4e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EGD99574.1 - 2e-05 24.2 0.2 5.2e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGD99574.1 - 5.5e-05 23.0 0.0 0.00014 21.8 0.0 1.7 1 1 1 2 2 1 1 AAA domain DUF815 PF05673.8 EGD99574.1 - 0.00011 21.1 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 EGD99574.1 - 0.00025 20.6 0.1 0.00085 18.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EGD99574.1 - 0.00069 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EGD99574.1 - 0.0019 17.6 0.0 0.0049 16.3 0.0 1.6 2 0 0 2 2 1 1 Sigma-54 interaction domain PhoH PF02562.11 EGD99574.1 - 0.0021 17.3 0.1 0.6 9.3 0.0 2.3 1 1 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 EGD99574.1 - 0.0037 16.7 0.0 0.069 12.6 0.0 2.4 2 1 1 3 3 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EGD99574.1 - 0.0061 15.5 0.0 0.0097 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EGD99574.1 - 0.0077 15.6 0.0 0.029 13.7 0.0 2.0 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EGD99574.1 - 0.0081 15.6 0.1 3.9 6.8 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EGD99574.1 - 0.0084 16.4 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EGD99574.1 - 0.011 15.1 0.0 0.25 10.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 EGD99574.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EGD99574.1 - 0.023 14.5 0.0 0.45 10.3 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EGD99574.1 - 0.025 14.2 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EGD99574.1 - 0.031 15.0 0.0 0.062 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGD99574.1 - 0.032 13.6 0.0 0.4 10.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGD99574.1 - 0.041 13.0 0.1 0.21 10.7 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI MiaE PF06175.6 EGD99574.1 - 0.049 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) RNA_helicase PF00910.17 EGD99574.1 - 0.057 13.5 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TAFII28 PF04719.9 EGD99574.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region SNF2_N PF00176.18 EGD99574.1 - 0.1 11.3 0.0 2.6 6.7 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain P21-Arc PF04062.9 EGD99575.1 - 1.3e-80 269.2 0.0 1.5e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NmrA PF05368.8 EGD99576.1 - 1.2e-17 63.9 0.0 1.6e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD99576.1 - 6.9e-16 58.7 0.1 1.3e-15 57.9 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EGD99576.1 - 9.4e-07 28.1 0.1 1.2e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EGD99576.1 - 1.2e-06 28.4 0.2 2.2e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EGD99576.1 - 3.2e-06 27.4 0.1 5.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EGD99576.1 - 1.5e-05 23.8 0.1 2.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGD99576.1 - 3.5e-05 23.3 0.1 5.4e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EGD99576.1 - 4.6e-05 23.4 0.7 0.00011 22.2 0.5 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 EGD99576.1 - 0.0017 17.3 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein ApbA PF02558.11 EGD99576.1 - 0.0017 17.8 0.1 0.0026 17.2 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.10 EGD99576.1 - 0.0095 14.8 0.1 0.012 14.4 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EGD99576.1 - 0.017 15.0 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EGD99576.1 - 0.038 12.8 0.1 0.063 12.1 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.5 EGD99576.1 - 0.093 12.3 0.1 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 KR domain Gp_dh_N PF00044.19 EGD99576.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CoA_binding PF02629.14 EGD99576.1 - 0.11 12.9 0.8 0.53 10.8 0.7 2.0 2 0 0 2 2 2 0 CoA binding domain Pkinase PF00069.20 EGD99577.1 - 0.076 12.1 0.0 0.14 11.3 0.0 1.4 2 0 0 2 2 2 0 Protein kinase domain APH PF01636.18 EGD99578.1 - 2.5e-09 37.2 0.0 6e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGD99578.1 - 0.086 11.9 0.1 2.5 7.0 0.0 2.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EGD99579.1 - 1.2e-13 50.8 0.0 2.5e-12 46.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD99579.1 - 3.4e-06 26.3 0.0 8e-05 21.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD99579.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M35 PF02102.10 EGD99580.1 - 8.1e-102 340.5 14.5 9.1e-102 340.3 10.1 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGD99580.1 - 3.6e-07 30.7 2.3 4.6e-07 30.4 0.5 1.9 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EGD99580.1 - 0.0044 16.4 3.9 0.022 14.1 2.7 1.9 1 1 0 1 1 1 1 Putative peptidase family Aldo_ket_red PF00248.16 EGD99587.1 - 1.3e-38 132.5 0.1 6.3e-38 130.2 0.0 1.7 1 1 1 2 2 2 1 Aldo/keto reductase family Rsd_AlgQ PF04353.8 EGD99587.1 - 0.013 15.2 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ CDC45 PF02724.9 EGD99588.1 - 3.8 5.4 21.7 0.17 9.8 3.4 2.2 2 0 0 2 2 2 0 CDC45-like protein Ribosomal_S19e PF01090.14 EGD99589.1 - 2.7e-49 166.1 0.3 1.9e-48 163.4 0.2 1.9 1 1 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.2 EGD99590.1 - 5e-21 75.6 0.5 9.2e-21 74.7 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD99590.1 - 1.1e-11 44.6 0.0 1e-10 41.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD99590.1 - 8.5e-09 35.3 0.0 8.5e-08 32.0 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold DSPc PF00782.15 EGD99590.1 - 2.4e-07 30.3 0.0 7.2e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF2305 PF10230.4 EGD99590.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 EGD99590.1 - 0.00061 19.4 0.1 0.0014 18.2 0.1 1.5 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.8 EGD99590.1 - 0.0013 18.3 0.2 0.0034 17.0 0.2 1.6 1 1 0 1 1 1 1 PGAP1-like protein Y_phosphatase PF00102.22 EGD99590.1 - 0.003 16.9 0.0 0.0083 15.4 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGD99590.1 - 0.023 14.7 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Thioesterase PF00975.15 EGD99590.1 - 0.054 13.7 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain LCAT PF02450.10 EGD99590.1 - 0.08 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 EGD99590.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.3 EGD99590.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Y_phosphatase3 PF13350.1 EGD99590.1 - 0.17 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family ILVD_EDD PF00920.16 EGD99591.1 - 3.1e-203 675.9 2.8 3.5e-203 675.7 2.0 1.0 1 0 0 1 1 1 1 Dehydratase family InvH PF04741.7 EGD99591.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein DUF1772 PF08592.6 EGD99592.1 - 3e-22 78.8 0.3 7.7e-22 77.5 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Pex2_Pex12 PF04757.9 EGD99593.1 - 4.5e-40 137.4 1.0 6.4e-40 136.9 0.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 EGD99593.1 - 0.019 14.5 2.5 0.051 13.2 1.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGD99593.1 - 0.022 14.6 5.6 0.022 14.6 3.9 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD99593.1 - 0.3 10.8 4.8 1.2 8.9 0.4 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EGD99593.1 - 0.37 10.8 9.4 1.9 8.6 4.3 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBN_N PF03810.14 EGD99594.1 - 7.9e-13 48.1 0.0 3.6e-12 46.0 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EGD99594.1 - 0.00023 21.1 1.3 0.013 15.3 0.0 3.5 3 1 0 4 4 4 1 Exportin 1-like protein Cellulase PF00150.13 EGD99595.1 - 7.4e-15 54.8 0.1 7.4e-15 54.8 0.0 1.8 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) GST_N_3 PF13417.1 EGD99596.1 - 5.9e-11 42.4 0.1 6.9e-10 39.0 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD99596.1 - 3.9e-08 33.1 0.1 6.5e-07 29.2 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD99596.1 - 4.8e-08 32.7 0.3 1.1e-07 31.6 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGD99596.1 - 0.0047 16.8 0.0 0.0078 16.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GPI-anchored PF10342.4 EGD99597.1 - 2.7e-24 85.4 0.0 5.9e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_transf_90 PF05686.7 EGD99598.1 - 8.3e-37 126.8 4.7 2.4e-36 125.2 3.3 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EGD99598.1 - 0.0053 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pex14_N PF04695.8 EGD99601.1 - 0.22 11.5 0.8 0.25 11.4 0.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF16 PF01519.11 EGD99602.1 - 0.0042 17.2 5.0 0.0095 16.1 3.5 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF16 Fib_alpha PF08702.5 EGD99602.1 - 7.3 6.7 7.2 34 4.5 2.4 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Gly_transf_sug PF04488.10 EGD99603.1 - 9.7e-10 38.7 0.8 2.3e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif MAP7 PF05672.6 EGD99603.1 - 0.012 15.0 26.0 0.019 14.3 18.0 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Caps_synth PF05704.7 EGD99603.1 - 0.023 13.8 0.0 0.023 13.8 0.0 2.1 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein AAA_23 PF13476.1 EGD99603.1 - 0.035 14.4 6.2 0.057 13.7 4.3 1.3 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.6 EGD99603.1 - 0.11 10.7 13.5 0.15 10.3 9.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Atg14 PF10186.4 EGD99603.1 - 0.25 10.2 10.4 0.36 9.7 7.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RR_TM4-6 PF06459.7 EGD99603.1 - 0.59 9.9 13.0 1.3 8.8 9.0 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HAUS6_N PF14661.1 EGD99603.1 - 0.99 8.7 11.5 15 4.8 8.5 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF1510 PF07423.6 EGD99603.1 - 1.3 8.3 18.7 2.5 7.4 13.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 EGD99603.1 - 5.1 4.6 11.7 7.1 4.2 8.1 1.1 1 0 0 1 1 1 0 Ycf1 CENP-I PF07778.6 EGD99603.1 - 5.4 5.0 6.2 3.9 5.5 1.8 2.0 1 1 1 2 2 2 0 Mis6 DDHD PF02862.12 EGD99603.1 - 6.9 6.3 8.2 13 5.4 5.7 1.4 1 0 0 1 1 1 0 DDHD domain DUF4407 PF14362.1 EGD99603.1 - 6.9 5.5 15.5 0.16 10.8 4.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2462 PF09495.5 EGD99604.1 - 2e-21 76.5 12.4 2.8e-21 76.0 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) DUF2413 PF10310.4 EGD99605.1 - 1.9e-140 468.5 0.0 2.2e-140 468.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 EGD99605.1 - 0.033 14.2 0.1 0.099 12.6 0.1 1.8 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain MSA-2c PF12238.3 EGD99605.1 - 1 8.9 3.8 2.4 7.7 2.7 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c OB_NTP_bind PF07717.11 EGD99607.1 - 1.3e-24 86.1 0.0 7.3e-23 80.5 0.0 2.6 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGD99607.1 - 3.6e-24 84.7 0.0 1.8e-23 82.4 0.0 2.3 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGD99607.1 - 5.5e-14 51.7 0.0 1.9e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD99607.1 - 1.6e-06 27.7 0.1 4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EGD99607.1 - 0.00021 20.2 0.0 0.0015 17.5 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 EGD99607.1 - 0.00061 19.9 0.1 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EGD99607.1 - 0.0014 18.5 0.0 0.69 9.7 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EGD99607.1 - 0.0064 15.5 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EGD99607.1 - 0.0067 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 KaiC SRP54 PF00448.17 EGD99607.1 - 0.011 15.1 0.2 0.033 13.6 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EGD99607.1 - 0.011 15.5 0.2 0.073 12.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGD99607.1 - 0.045 14.0 0.4 0.69 10.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain Flavi_DEAD PF07652.9 EGD99607.1 - 0.049 13.3 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Glug PF07581.7 EGD99607.1 - 0.07 13.3 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 The GLUG motif NACHT PF05729.7 EGD99607.1 - 0.075 12.6 1.5 0.73 9.4 0.1 2.5 3 0 0 3 3 3 0 NACHT domain DAD PF02109.11 EGD99608.1 - 5.3e-40 136.0 2.9 4.7e-39 132.9 2.0 1.9 1 1 0 1 1 1 1 DAD family Tmemb_14 PF03647.8 EGD99609.1 - 4.8e-22 78.1 8.6 7.3e-22 77.5 6.0 1.3 1 0 0 1 1 1 1 Transmembrane proteins 14C RTC4 PF14474.1 EGD99610.1 - 1.1e-36 125.4 0.1 1.9e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain DUF726 PF05277.7 EGD99611.1 - 5e-129 430.1 2.2 8.6e-129 429.3 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) NUDIX PF00293.23 EGD99612.1 - 2.3e-07 30.5 0.1 6e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain Baculo_PP31 PF05311.6 EGD99612.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Metallophos PF00149.23 EGD99613.1 - 7.1e-12 45.1 0.2 4.3e-11 42.5 0.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD99613.1 - 1.9e-09 37.5 0.0 3.7e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EGD99613.1 - 0.0024 17.0 0.0 0.0071 15.5 0.0 1.6 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily Mito_carr PF00153.22 EGD99614.1 - 5.7e-75 247.1 0.6 1e-25 89.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 EGD99614.1 - 6.4e-13 47.4 3.5 2.8e-07 29.8 0.1 5.9 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.1 EGD99614.1 - 7.7e-12 45.1 5.4 1e-08 35.1 0.7 4.0 3 2 2 5 5 5 2 EF-hand domain pair EF-hand_1 PF00036.27 EGD99614.1 - 4.6e-11 41.1 10.5 3.9e-07 28.9 0.1 5.6 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.1 EGD99614.1 - 4.8e-10 38.9 2.5 0.079 12.5 0.0 4.9 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EGD99614.1 - 7.1e-07 28.2 8.4 3.4e-05 22.9 0.1 4.9 5 0 0 5 5 5 1 EF hand EF-hand_9 PF14658.1 EGD99614.1 - 0.076 12.9 0.0 9.1 6.2 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain Pyr_redox_3 PF13738.1 EGD99616.1 - 1.6e-24 87.0 0.0 2.6e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGD99616.1 - 4.4e-12 44.9 0.1 9.9e-11 40.5 0.0 2.5 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGD99616.1 - 2.2e-11 43.6 0.1 7.8e-08 32.2 0.0 3.2 2 1 1 3 3 3 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGD99616.1 - 7.1e-07 29.2 0.0 3.7e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD99616.1 - 9e-07 28.1 0.0 0.0036 16.2 0.0 3.2 3 1 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EGD99616.1 - 1.2e-05 24.4 0.2 4.1e-05 22.6 0.0 1.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EGD99616.1 - 0.00012 22.4 0.1 0.2 12.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD99616.1 - 0.00017 21.4 0.4 0.85 9.3 0.2 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EGD99616.1 - 0.0022 17.1 0.2 0.031 13.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 EGD99616.1 - 0.0041 17.2 0.0 0.46 10.5 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EGD99616.1 - 0.013 14.3 0.0 0.25 10.1 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EGD99616.1 - 0.049 12.5 0.0 1.5 7.6 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 EGD99616.1 - 0.16 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_transf_25 PF01755.12 EGD99617.1 - 9.2e-06 25.4 0.0 3.7e-05 23.4 0.0 1.9 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Consortin_C PF15281.1 EGD99619.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Consortin C-terminus Peptidase_M22 PF00814.20 EGD99620.1 - 3.1e-45 154.7 0.0 1.6e-40 139.3 0.0 3.5 2 1 0 2 2 2 2 Glycoprotease family zf-HC5HC2H_2 PF13832.1 EGD99623.1 - 4.9e-33 113.4 3.5 4.9e-33 113.4 2.4 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGD99623.1 - 4.9e-28 97.1 1.2 4.9e-28 97.1 0.8 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EGD99623.1 - 1.7e-24 86.8 0.0 1.7e-24 86.8 0.0 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 EGD99623.1 - 5.4e-14 51.2 3.2 5.4e-14 51.2 2.2 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EGD99623.1 - 5.1e-08 32.4 25.1 7.4e-08 31.9 6.9 2.7 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.20 EGD99623.1 - 0.014 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Bromodomain RRM_1 PF00076.17 EGD99624.1 - 2e-19 68.9 0.0 3.1e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD99624.1 - 7.1e-18 64.3 0.0 1.1e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD99624.1 - 9.7e-12 44.5 0.0 1.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dpy-30 PF05186.8 EGD99625.1 - 1.9e-14 52.8 0.0 2.7e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif VRR_NUC PF08774.6 EGD99626.1 - 1.1e-17 63.9 0.0 4.4e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 VRR-NUC domain Ribosomal_S13_N PF08069.7 EGD99627.1 - 1.5e-29 101.5 0.1 1.9e-29 101.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain PAX PF00292.13 EGD99627.1 - 0.0082 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 'Paired box' domain Chromate_transp PF02417.10 EGD99628.1 - 3.3e-48 163.4 31.9 7.7e-25 87.4 8.2 2.5 3 0 0 3 3 3 2 Chromate transporter Oxidored_q2 PF00420.19 EGD99628.1 - 1.5 8.4 9.5 0.48 10.0 0.2 3.3 2 2 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4490 PF14892.1 EGD99630.1 - 0.0079 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) 7tm_2 PF00002.19 EGD99631.1 - 0.02 13.9 11.0 0.046 12.7 7.4 1.8 1 1 1 2 2 2 0 7 transmembrane receptor (Secretin family) DUF3082 PF11282.3 EGD99631.1 - 0.022 14.8 1.9 0.036 14.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) SdpI PF13630.1 EGD99631.1 - 0.42 10.3 10.0 0.44 10.2 0.1 4.0 3 1 1 4 4 4 0 SdpI/YhfL protein family RRM_1 PF00076.17 EGD99632.1 - 7.5e-30 102.3 0.1 8.4e-13 47.7 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD99632.1 - 4.8e-22 77.7 0.0 1.3e-05 25.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD99632.1 - 4.7e-17 61.5 0.0 3.9e-08 33.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EGD99632.1 - 6.2 5.1 12.5 8.5 4.7 8.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 OGG_N PF07934.7 EGD99633.1 - 2e-17 63.2 0.2 4.4e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EGD99633.1 - 2e-15 57.0 0.0 3.2e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGD99633.1 - 0.00072 19.1 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif NMT PF01233.14 EGD99633.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Pyr_redox_3 PF13738.1 EGD99634.1 - 2.1e-25 90.0 0.0 2.5e-22 79.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGD99634.1 - 9.3e-12 43.9 1.7 1.3e-10 40.1 0.6 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.19 EGD99634.1 - 1.3e-10 40.7 0.0 0.00011 21.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGD99634.1 - 2e-09 37.6 0.0 2e-05 24.5 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD99634.1 - 3.8e-09 35.9 1.8 1e-05 24.6 0.0 3.5 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGD99634.1 - 1.3e-08 34.7 0.7 4.8e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGD99634.1 - 2e-05 24.4 0.0 0.093 12.5 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.12 EGD99634.1 - 0.00052 19.1 0.0 0.019 14.0 0.0 2.5 3 0 0 3 3 3 1 Thi4 family Mqo PF06039.10 EGD99634.1 - 0.0024 16.1 0.0 0.37 8.8 0.0 2.3 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.17 EGD99634.1 - 0.0026 16.6 0.2 0.13 11.0 0.0 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EGD99634.1 - 0.045 12.2 0.2 7.3 4.9 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.7 EGD99634.1 - 0.051 12.4 0.0 3.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein APH PF01636.18 EGD99635.1 - 1.5e-07 31.3 1.6 2.2e-07 30.8 0.1 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Zn_clus PF00172.13 EGD99636.1 - 2.1e-08 33.8 11.7 4e-08 33.0 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGD99636.1 - 2.1e-06 26.6 2.2 3.7e-06 25.7 1.5 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Rax2 PF12768.2 EGD99637.1 - 1.9e-102 342.2 3.3 2.1e-92 309.3 0.0 5.3 5 1 1 6 6 6 4 Cortical protein marker for cell polarity SSrecog PF03531.9 EGD99638.1 - 6.5e-70 234.9 1.1 3e-68 229.4 0.8 2.9 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EGD99638.1 - 6.4e-28 96.5 0.2 2.5e-27 94.6 0.1 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SAP PF02037.22 EGD99639.1 - 4e-12 45.3 0.1 9.6e-12 44.1 0.1 1.7 1 0 0 1 1 1 1 SAP domain CCT_2 PF09425.5 EGD99639.1 - 0.09 12.3 5.8 2.8 7.5 0.8 2.7 2 0 0 2 2 2 0 Divergent CCT motif MRL1 PF13003.2 EGD99640.1 - 0.084 12.6 0.2 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L1 DUF3464 PF11947.3 EGD99640.1 - 0.14 11.6 0.9 0.19 11.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Methyltransf_11 PF08241.7 EGD99641.1 - 0.0015 18.9 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EGD99641.1 - 0.03 13.3 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF3455 PF11937.3 EGD99642.1 - 1.1e-18 67.8 0.0 1.5e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) SF3b1 PF08920.5 EGD99643.1 - 4.1e-41 140.4 0.5 4.1e-41 140.4 0.4 2.4 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EGD99643.1 - 3.1e-14 52.9 4.5 0.011 16.0 0.0 7.2 5 3 2 7 7 7 5 HEAT repeats HEAT PF02985.17 EGD99643.1 - 1.1e-10 40.6 9.5 1 9.6 0.0 9.4 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 EGD99643.1 - 1.2e-08 35.1 5.7 0.53 10.8 0.0 7.1 5 2 2 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGD99643.1 - 1.3e-05 25.4 0.2 1.1 9.6 0.0 5.5 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.7 EGD99643.1 - 0.0054 16.1 0.4 4.1 6.7 0.0 3.8 4 0 0 4 4 4 1 NUC173 domain CLASP_N PF12348.3 EGD99643.1 - 0.0091 15.3 0.2 1 8.6 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal CRM1_C PF08767.6 EGD99643.1 - 0.071 12.0 0.8 0.29 9.9 0.0 2.3 3 0 0 3 3 3 0 CRM1 C terminal Sec1 PF00995.18 EGD99644.1 - 1.3e-131 439.9 0.0 1.6e-131 439.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family V-SNARE_C PF12352.3 EGD99645.1 - 1.1 9.3 7.1 0.077 13.0 0.6 2.3 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus zf-C2H2 PF00096.21 EGD99646.1 - 2.6e-10 39.9 11.2 1.1e-05 25.4 3.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD99646.1 - 4.4e-09 36.1 23.5 4.6e-06 26.6 0.2 3.8 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGD99646.1 - 1.5e-07 31.2 8.0 0.00012 22.1 1.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EGD99646.1 - 2.2e-06 27.6 2.9 2.1e-05 24.5 0.9 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGD99646.1 - 3e-05 24.0 6.6 0.00011 22.1 1.5 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGD99646.1 - 0.00039 20.2 7.3 0.0079 16.0 1.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EGD99646.1 - 0.14 11.8 4.0 6.2 6.6 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 EGD99646.1 - 0.37 10.5 5.5 0.1 12.3 0.6 2.1 2 0 0 2 2 2 0 BED zinc finger APC_CDC26 PF10471.4 EGD99646.1 - 0.6 10.8 12.6 1.5 9.6 8.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 NinG PF05766.7 EGD99646.1 - 0.92 9.2 8.6 3 7.5 0.7 2.3 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein DUF4175 PF13779.1 EGD99646.1 - 2.4 5.7 11.4 3.2 5.3 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 EGD99646.1 - 5.6 6.6 7.8 1.6 8.3 3.6 1.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) MDM1 PF15501.1 EGD99647.1 - 0.012 14.5 5.3 0.013 14.4 3.7 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 Selenoprotein_S PF06936.6 EGD99647.1 - 0.12 11.8 9.2 0.14 11.6 6.4 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) Ydc2-catalyt PF09159.5 EGD99647.1 - 0.2 11.1 3.8 0.21 11.0 2.6 1.1 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Cytotoxic PF09000.5 EGD99647.1 - 3.5 7.7 11.3 0.82 9.7 4.5 2.0 1 1 1 2 2 2 0 Cytotoxic CKAP2_C PF15297.1 EGD99648.1 - 0.049 12.4 0.1 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus YL1 PF05764.8 EGD99648.1 - 0.18 11.4 4.3 0.2 11.2 3.0 1.0 1 0 0 1 1 1 0 YL1 nuclear protein FAD_binding_2 PF00890.19 EGD99651.1 - 1.5e-45 155.7 0.1 1e-44 153.0 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EGD99651.1 - 2.9e-09 36.5 0.1 2.5e-08 33.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EGD99651.1 - 8.3e-09 34.8 0.8 1.6e-07 30.5 0.6 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGD99651.1 - 1.6e-06 26.9 2.6 0.00073 18.1 0.1 3.2 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.9 EGD99651.1 - 4e-06 26.8 0.0 0.00099 19.0 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD99651.1 - 1.3e-05 25.3 0.2 0.00094 19.2 0.2 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGD99651.1 - 0.00073 18.6 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGD99651.1 - 0.002 18.1 0.1 0.0085 16.1 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EGD99651.1 - 0.0029 16.5 0.3 0.0029 16.5 0.2 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 EGD99651.1 - 0.0037 16.3 0.1 0.0071 15.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EGD99651.1 - 0.032 13.1 0.1 0.057 12.3 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EGD99651.1 - 0.049 13.1 0.1 0.094 12.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.13 EGD99652.1 - 4e-25 88.1 0.1 6.9e-25 87.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD99652.1 - 2.7e-08 33.5 11.6 5.4e-08 32.6 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Telomere_reg-2 PF10193.4 EGD99653.1 - 4.6e-30 104.2 0.0 1.2e-29 102.9 0.0 1.8 1 0 0 1 1 1 1 Telomere length regulation protein ThiF PF00899.16 EGD99654.1 - 7.3e-37 126.2 0.1 1.7e-36 125.0 0.0 1.6 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EGD99654.1 - 2.5e-29 100.8 0.1 4.3e-29 100.0 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EGD99654.1 - 2e-24 84.9 0.2 3.8e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGD99654.1 - 1.9e-14 52.7 2.2 1.9e-14 52.7 1.5 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 EGD99654.1 - 0.00034 20.1 0.0 0.00069 19.1 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain UBA_e1_C PF09358.5 EGD99654.1 - 0.004 17.2 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain Ecm33 PF12454.3 EGD99654.1 - 0.042 13.7 2.3 0.092 12.6 1.6 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein RNA_pol_A_bac PF01000.21 EGD99655.1 - 2.5e-27 95.2 0.0 4.6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGD99655.1 - 6.5e-13 47.6 0.0 8.6e-13 47.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.14 EGD99656.1 - 5.3e-133 442.1 0.0 7.1e-133 441.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit UQ_con PF00179.21 EGD99657.1 - 5.5e-25 87.4 0.0 6.2e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD99657.1 - 9.7e-06 25.3 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGD99657.1 - 4.3e-05 23.3 0.0 5.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain MKT1_C PF12246.3 EGD99658.1 - 8.8e-76 254.1 0.0 1.3e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EGD99658.1 - 3.5e-30 104.1 0.1 8.1e-30 102.9 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EGD99658.1 - 8.1e-13 48.2 0.0 1.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region DIOX_N PF14226.1 EGD99659.1 - 1.5e-16 60.9 0.0 1.8e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal zf-MYND PF01753.13 EGD99660.1 - 3.6e-08 33.1 21.0 8.1e-08 32.0 14.5 1.6 1 0 0 1 1 1 1 MYND finger PAT1 PF09770.4 EGD99660.1 - 0.068 11.4 20.3 0.082 11.1 14.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 EGD99660.1 - 0.19 10.1 5.8 0.22 9.8 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_60s PF00428.14 EGD99660.1 - 0.76 10.2 6.0 2 8.8 1.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein SOG2 PF10428.4 EGD99660.1 - 2.3 6.7 15.2 2.8 6.5 10.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SR-25 PF10500.4 EGD99660.1 - 2.4 7.5 14.5 4.6 6.6 10.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2638 PF10937.3 EGD99660.1 - 3.1 8.8 14.1 0.18 12.8 6.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) Presenilin PF01080.12 EGD99660.1 - 3.7 6.2 4.5 5 5.8 3.1 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.8 EGD99660.1 - 6.5 6.5 16.8 8 6.2 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HLH PF00010.21 EGD99662.1 - 2.7e-12 46.1 0.0 8.2e-12 44.6 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mito_carr PF00153.22 EGD99663.1 - 5.4e-69 227.9 1.3 8.2e-25 86.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Dna2 PF08696.6 EGD99664.1 - 8e-69 231.1 0.0 1.4e-68 230.3 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EGD99664.1 - 2.2e-52 177.3 0.0 4.5e-52 176.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGD99664.1 - 2.9e-41 141.6 0.1 2.3e-21 76.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 EGD99664.1 - 1.6e-13 50.6 0.0 3.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 EGD99664.1 - 6.9e-12 45.2 0.0 1.7e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.1 EGD99664.1 - 2.7e-10 39.8 0.2 7.4e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 EGD99664.1 - 8.6e-10 38.7 0.0 3.4e-07 30.3 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 EGD99664.1 - 5.5e-07 29.3 0.5 0.18 11.3 0.0 4.0 4 0 0 4 4 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EGD99664.1 - 6.6e-05 22.6 0.0 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 EGD99664.1 - 0.00055 19.3 0.8 0.0012 18.2 0.1 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 EGD99664.1 - 0.00074 19.0 0.2 0.0016 17.9 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.9 EGD99664.1 - 0.0019 17.9 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF911 PF06023.7 EGD99664.1 - 0.0019 17.4 0.0 0.0092 15.2 0.0 2.0 1 1 0 1 1 1 1 Archaeal protein of unknown function (DUF911) CbiA PF01656.18 EGD99664.1 - 0.0022 17.4 0.0 0.0048 16.3 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 EGD99664.1 - 0.0027 17.1 0.0 0.0062 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EGD99664.1 - 0.0035 17.8 0.0 0.0084 16.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EGD99664.1 - 0.0056 16.6 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EGD99664.1 - 0.0067 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 EGD99664.1 - 0.014 14.3 0.2 0.047 12.6 0.2 1.8 1 1 0 1 1 1 0 PIF1-like helicase DUF87 PF01935.12 EGD99664.1 - 0.042 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA PF00004.24 EGD99664.1 - 0.051 13.7 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EGD99664.1 - 0.087 12.5 0.2 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 EGD99664.1 - 0.1 12.7 0.1 0.34 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGD99664.1 - 0.1 12.0 0.1 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EGD99664.1 - 0.15 11.7 0.0 0.41 10.3 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase ArgK PF03308.11 EGD99664.1 - 0.16 10.7 0.1 0.32 9.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein NB-ARC PF00931.17 EGD99664.1 - 0.18 10.6 0.3 1.5 7.5 0.1 2.4 3 0 0 3 3 3 0 NB-ARC domain Ribonuc_P_40 PF08584.6 EGD99665.1 - 7.1e-85 284.4 0.0 8.5e-85 284.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.27 EGD99666.1 - 2.5e-37 125.4 11.3 5.3e-09 35.6 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGD99666.1 - 1.8e-07 29.8 0.0 0.0018 16.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EGD99666.1 - 3.7e-05 23.5 0.0 0.051 13.2 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGD99666.1 - 0.028 12.5 0.1 2 6.4 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 EGD99666.1 - 0.064 12.9 1.0 16 5.1 0.0 3.3 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term DPPIV_N PF00930.16 EGD99666.1 - 0.064 11.8 0.0 0.26 9.8 0.0 1.9 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Apc4_WD40 PF12894.2 EGD99666.1 - 0.071 12.6 0.0 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain FlgD_ig PF13860.1 EGD99666.1 - 0.13 11.9 0.6 1.5 8.5 0.0 2.6 3 0 0 3 3 3 0 FlgD Ig-like domain IKI3 PF04762.7 EGD99666.1 - 0.35 8.6 0.5 8.4 4.0 0.0 2.4 2 1 0 3 3 3 0 IKI3 family Fungal_trans PF04082.13 EGD99667.1 - 7.3e-19 67.6 0.1 1.3e-18 66.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD99667.1 - 7e-10 38.6 9.6 1.6e-09 37.5 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L2_C PF03947.13 EGD99668.1 - 4.6e-45 152.5 3.1 5.6e-34 116.7 1.0 2.4 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGD99668.1 - 4.3e-25 87.4 0.4 9e-25 86.4 0.3 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 EGD99669.1 - 2.2e-46 156.5 0.1 3.3e-44 149.5 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGD99669.1 - 1.9e-31 108.4 0.1 4.1e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain HIT PF01230.18 EGD99670.1 - 2.2e-16 60.1 0.0 7.3e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EGD99670.1 - 1.7e-06 28.2 0.0 3.9e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGD99670.1 - 0.13 11.9 2.7 0.33 10.6 0.0 2.3 3 0 0 3 3 3 0 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.13 EGD99671.1 - 3.9e-12 46.1 0.0 6.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EGD99671.1 - 1.4e-09 37.9 0.0 5.6e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.11 EGD99671.1 - 0.00059 19.0 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.10 EGD99671.1 - 0.078 12.4 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase DUF2985 PF11204.3 EGD99673.1 - 9.1e-29 99.0 6.3 1.7e-28 98.1 3.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) LTXXQ PF07813.7 EGD99673.1 - 0.00049 20.5 0.4 0.00049 20.5 0.2 2.5 2 0 0 2 2 2 1 LTXXQ motif family protein DUF1726 PF08351.6 EGD99673.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) Peptidase_S49_N PF08496.5 EGD99673.1 - 3.8 7.2 9.1 4 7.2 4.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal APH PF01636.18 EGD99674.1 - 0.00016 21.4 0.0 0.00016 21.4 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGD99674.1 - 0.00023 20.3 0.0 0.00047 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EGD99674.1 - 0.00039 19.5 0.0 0.00092 18.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HSDR_N_2 PF13588.1 EGD99674.1 - 0.066 13.0 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.15 EGD99674.1 - 0.072 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Dysbindin PF04440.11 EGD99674.1 - 0.65 9.7 6.6 0.56 9.9 2.6 2.3 2 0 0 2 2 2 0 Dysbindin (Dystrobrevin binding protein 1) SIR2 PF02146.12 EGD99675.1 - 7.3e-60 201.7 0.0 1e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EGD99675.1 - 1.1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EGD99675.1 - 0.0013 18.4 0.2 0.92 9.2 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain TPR_19 PF14559.1 EGD99676.1 - 3.2e-12 46.5 1.7 1.8e-06 28.1 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD99676.1 - 6.7e-12 45.1 0.0 1.3e-07 31.4 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGD99676.1 - 1.3e-11 43.5 0.0 7e-05 22.4 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD99676.1 - 4.5e-11 42.2 0.0 1.3e-06 27.9 0.0 3.6 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.1 EGD99676.1 - 1.3e-09 37.8 1.1 0.15 12.8 0.0 5.5 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGD99676.1 - 4.5e-09 35.5 0.0 0.00026 20.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD99676.1 - 1.7e-07 31.7 0.0 2.7 8.7 0.0 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGD99676.1 - 4.6e-07 29.1 0.0 1.7e-05 24.2 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGD99676.1 - 1.3e-05 24.9 0.7 0.84 9.5 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGD99676.1 - 8.8e-05 22.3 0.3 0.059 13.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD99676.1 - 0.00011 21.7 0.0 0.013 15.2 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EGD99676.1 - 0.0012 18.9 0.0 0.15 12.1 0.0 3.1 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 EGD99676.1 - 0.02 14.1 0.6 1.4 8.2 0.0 2.7 2 0 0 2 2 2 0 SHNi-TPR TPR_17 PF13431.1 EGD99676.1 - 0.025 14.7 0.0 24 5.4 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 EGD99676.1 - 0.035 14.0 0.0 1.8 8.5 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGD99676.1 - 0.13 12.7 0.4 5.2 7.7 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat C_GCAxxG_C_C PF09719.5 EGD99676.1 - 0.13 12.0 0.0 0.5 10.1 0.0 1.9 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) RWD PF05773.17 EGD99677.1 - 2.9e-23 81.9 0.7 2.9e-23 81.9 0.5 1.5 2 0 0 2 2 2 1 RWD domain DUF1485 PF07364.7 EGD99677.1 - 0.00027 20.2 0.0 0.0029 16.8 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1485) RNase_H2-Ydr279 PF09468.5 EGD99677.1 - 0.0091 15.2 0.8 0.01 15.0 0.6 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Pyridox_oxidase PF01243.15 EGD99678.1 - 3.7e-05 23.6 0.0 6.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GST_C PF00043.20 EGD99679.1 - 3.8e-17 62.0 0.1 6.6e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD99679.1 - 2.4e-14 53.2 0.0 4.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGD99679.1 - 2.7e-11 43.5 0.0 4.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD99679.1 - 4.7e-11 42.5 0.0 9.9e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD99679.1 - 2.3e-09 37.0 0.3 8.9e-09 35.1 0.1 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD99679.1 - 9.5e-05 22.8 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Complex1_LYR_1 PF13232.1 EGD99680.1 - 8.3e-13 48.3 2.3 8.4e-13 48.3 0.1 2.1 2 1 1 3 3 3 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGD99680.1 - 1.6e-09 37.4 0.2 4.7e-09 35.8 0.1 1.9 1 0 0 1 1 1 1 Complex 1 protein (LYR family) YflT PF11181.3 EGD99680.1 - 0.073 13.2 0.3 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Heat induced stress protein YflT UQ_con PF00179.21 EGD99681.1 - 7.8e-18 64.2 0.0 8.4e-18 64.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGD99681.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain Sec7_N PF12783.2 EGD99682.1 - 7.1e-40 136.1 5.9 7.1e-40 136.1 4.1 4.1 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGD99682.1 - 0.00015 21.1 0.1 0.019 14.5 0.0 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Antimicrobial19 PF08225.6 EGD99682.1 - 0.21 11.0 1.2 0.46 9.9 0.0 2.3 2 0 0 2 2 2 0 Pseudin antimicrobial peptide Vps26 PF03643.10 EGD99683.1 - 9.7e-129 427.9 0.1 1.2e-128 427.7 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EGD99683.1 - 0.0032 17.2 0.4 3.3 7.5 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 EGD99683.1 - 0.056 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF432) AAA_33 PF13671.1 EGD99684.1 - 2.8e-12 46.7 0.0 9.3e-12 45.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD99684.1 - 1.2e-11 45.0 0.0 2.4e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 EGD99684.1 - 4.9e-11 42.7 0.0 1.7e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 EGD99684.1 - 1.2e-10 42.2 0.0 1.6e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EGD99684.1 - 3.2e-06 26.1 0.0 4.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EGD99684.1 - 6.2e-05 23.1 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGD99684.1 - 9.6e-05 22.2 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EGD99684.1 - 0.00018 21.4 0.0 0.0061 16.4 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_22 PF13401.1 EGD99684.1 - 0.00019 21.6 0.1 0.00036 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EGD99684.1 - 0.00044 19.9 0.0 0.00089 18.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EGD99684.1 - 0.00045 19.9 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EGD99684.1 - 0.0012 18.7 0.0 0.0025 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGD99684.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EGD99684.1 - 0.0055 16.7 0.2 0.024 14.5 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.15 EGD99684.1 - 0.007 16.0 0.0 0.022 14.4 0.0 1.8 1 1 0 1 1 1 1 Adenylylsulphate kinase T2SE PF00437.15 EGD99684.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 EGD99684.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EGD99684.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase PRK PF00485.13 EGD99684.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.11 EGD99684.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein tRNA_lig_kinase PF08303.6 EGD99684.1 - 0.019 14.8 0.0 0.046 13.5 0.0 1.7 2 0 0 2 2 2 0 tRNA ligase kinase domain Zeta_toxin PF06414.7 EGD99684.1 - 0.02 13.9 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EGD99684.1 - 0.021 13.7 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EGD99684.1 - 0.026 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EGD99684.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EGD99684.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGD99684.1 - 0.031 13.7 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EGD99684.1 - 0.034 13.8 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 NTPase CoaE PF01121.15 EGD99684.1 - 0.04 13.3 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_24 PF13479.1 EGD99684.1 - 0.045 13.3 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGD99684.1 - 0.049 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGD99684.1 - 0.056 12.6 0.0 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EGD99684.1 - 0.064 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Herpes_Helicase PF02689.9 EGD99684.1 - 0.065 10.9 0.0 0.084 10.5 0.0 1.1 1 0 0 1 1 1 0 Helicase PduV-EutP PF10662.4 EGD99684.1 - 0.082 12.4 0.0 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ADK PF00406.17 EGD99684.1 - 0.11 12.3 0.1 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase Acetyltransf_3 PF13302.1 EGD99685.1 - 1.5e-16 60.8 0.0 2e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_C14 PF00656.17 EGD99686.1 - 2.9e-70 236.7 0.0 3.6e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain 2-oxoacid_dh PF00198.18 EGD99687.1 - 1.9e-80 269.4 0.7 2.6e-80 269.0 0.5 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 EGD99687.1 - 2.5e-14 52.6 1.1 3.8e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl PF00364.17 EGD99687.1 - 3e-12 46.0 0.0 8.9e-12 44.4 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF3597 PF12200.3 EGD99687.1 - 1.5 9.2 5.8 1 9.7 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) PI-PLC-X PF00388.14 EGD99688.1 - 1e-13 50.9 0.0 1.9e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.15 EGD99689.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L10 Auxin_repressed PF05564.7 EGD99689.1 - 0.11 13.1 0.2 0.21 12.2 0.2 1.5 1 0 0 1 1 1 0 Dormancy/auxin associated protein F-box PF00646.28 EGD99690.1 - 0.12 12.1 0.4 0.45 10.2 0.1 2.0 2 0 0 2 2 2 0 F-box domain Glycos_transf_3 PF00591.16 EGD99691.1 - 2.4e-56 190.9 0.0 1.3e-53 181.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EGD99691.1 - 8e-05 22.1 0.3 0.00023 20.6 0.2 1.8 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.8 EGD99692.1 - 3.8e-17 61.4 7.1 4.8e-17 61.1 4.9 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EGD99692.1 - 0.00038 20.1 0.2 0.00041 20.0 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DUF2318 PF10080.4 EGD99692.1 - 0.0025 17.5 0.1 0.0025 17.5 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) DUF2197 PF09963.4 EGD99692.1 - 0.0045 16.9 3.1 0.27 11.2 0.2 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) DZR PF12773.2 EGD99692.1 - 0.0046 16.7 0.2 0.0064 16.2 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon A2L_zn_ribbon PF08792.5 EGD99692.1 - 0.0067 15.8 2.4 0.084 12.3 0.2 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 EGD99692.1 - 0.0093 15.9 1.5 0.016 15.1 1.0 1.4 1 0 0 1 1 1 1 Zinc ribbon domain GFA PF04828.9 EGD99692.1 - 0.012 15.4 1.0 2.4 8.1 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2082 PF09855.4 EGD99692.1 - 0.097 12.5 1.4 0.18 11.6 1.0 1.6 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) UPF0547 PF10571.4 EGD99692.1 - 0.21 11.2 1.8 0.42 10.3 1.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 RRN7 PF11781.3 EGD99692.1 - 0.27 10.7 3.4 0.99 8.9 0.1 2.2 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF951 PF06107.6 EGD99692.1 - 0.28 10.7 3.2 1.4 8.5 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) Zn_Tnp_IS1595 PF12760.2 EGD99692.1 - 0.29 10.9 3.3 0.73 9.6 2.3 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TFIIS_C PF01096.13 EGD99692.1 - 0.56 9.8 4.9 4.9 6.8 0.6 2.4 1 1 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.1 EGD99692.1 - 0.87 9.8 6.0 2.4 8.4 0.7 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF3133 PF11331.3 EGD99692.1 - 7 6.3 6.4 1.8e+02 1.7 4.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3133) fn3 PF00041.16 EGD99693.1 - 4.3e-12 45.9 5.6 7.5e-07 29.2 0.0 4.3 4 1 0 4 4 4 2 Fibronectin type III domain Lipase_GDSL_2 PF13472.1 EGD99693.1 - 6.4e-09 36.1 0.3 4.1e-08 33.5 0.2 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGD99693.1 - 0.00051 19.9 0.0 0.0026 17.6 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fe_hyd_lg_C PF02906.9 EGD99696.1 - 2e-60 204.5 0.0 3.3e-60 203.7 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF2263 PF10021.4 EGD99697.1 - 7.5e-29 100.6 0.0 2.8e-28 98.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) Fapy_DNA_glyco PF01149.19 EGD99698.1 - 5.3e-25 88.0 0.0 9.3e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EGD99698.1 - 4e-21 74.5 0.0 7.3e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EGD99698.1 - 0.0046 15.5 0.0 0.016 13.7 0.0 1.7 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Mitofilin PF09731.4 EGD99698.1 - 0.012 14.2 7.0 0.016 13.8 4.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CaM_binding PF07839.6 EGD99698.1 - 0.4 10.8 5.2 0.81 9.9 3.6 1.5 1 0 0 1 1 1 0 Plant calmodulin-binding domain Cid2 PF09774.4 EGD99699.1 - 8e-52 175.3 0.0 9.3e-52 175.1 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.3 EGD99700.1 - 1.5e-209 697.0 9.0 1.5e-208 693.7 2.5 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 EGD99700.1 - 1.8e-25 87.0 9.1 0.00095 19.6 1.3 10.6 8 2 3 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.1 EGD99700.1 - 8.8e-23 79.7 31.5 4.7e-05 22.9 0.2 8.0 8 1 0 8 8 7 5 TPR repeat TPR_2 PF07719.12 EGD99700.1 - 7.3e-21 72.3 34.9 8e-05 22.2 0.4 10.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 EGD99700.1 - 1e-20 73.8 14.9 0.00085 19.9 0.7 8.1 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGD99700.1 - 1.1e-19 70.4 26.4 0.00017 21.8 0.0 7.1 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 EGD99700.1 - 5e-13 48.0 33.6 1.2e-05 24.7 0.4 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_9 PF13371.1 EGD99700.1 - 9.9e-12 44.5 13.6 0.014 15.2 0.0 7.4 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGD99700.1 - 9.6e-11 41.0 18.4 0.11 12.7 0.0 8.2 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGD99700.1 - 1.9e-09 37.3 25.4 0.0011 18.8 0.2 7.6 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGD99700.1 - 6e-09 35.0 19.2 0.0014 18.2 0.1 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EGD99700.1 - 3.4e-08 33.4 13.0 0.021 14.9 2.3 5.6 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGD99700.1 - 3.3e-07 29.6 11.6 0.47 10.3 0.3 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGD99700.1 - 2.2e-06 27.7 21.5 0.082 13.3 0.1 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 EGD99700.1 - 4.8e-06 25.8 12.8 0.0046 16.0 0.4 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 EGD99700.1 - 1.1e-05 25.1 3.5 0.013 15.2 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 EGD99700.1 - 5.4e-05 23.5 2.0 0.00073 19.8 0.2 3.1 2 0 0 2 2 2 1 Bacterial transcriptional activator domain MIT PF04212.13 EGD99700.1 - 0.00074 19.3 0.9 0.27 11.1 0.0 3.8 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_4 PF07721.9 EGD99700.1 - 0.0072 16.6 7.6 3.5 8.3 1.4 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGD99700.1 - 0.013 15.3 13.4 9.9 6.1 0.0 6.4 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Rapsyn_N PF10579.4 EGD99700.1 - 0.033 13.9 0.0 0.19 11.5 0.0 2.4 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.1 EGD99700.1 - 0.077 12.9 16.0 17 5.5 1.4 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Tim54 PF11711.3 EGD99701.1 - 6.2e-130 433.2 0.1 7.3e-130 432.9 0.0 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.20 EGD99702.1 - 1.1e-53 182.1 0.1 1.6e-37 129.0 0.2 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD99702.1 - 3.1e-24 85.4 0.3 7.5e-19 67.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGD99702.1 - 9.7e-05 21.4 0.0 0.0002 20.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD99702.1 - 0.00045 20.0 0.2 0.017 14.8 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD99702.1 - 0.0015 17.6 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EGD99702.1 - 0.013 15.9 0.0 0.037 14.5 0.0 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 EGD99702.1 - 0.041 12.7 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PepX_N PF09168.5 EGD99702.1 - 0.051 13.8 0.6 0.11 12.6 0.4 1.5 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Pox_ser-thr_kin PF05445.6 EGD99702.1 - 0.068 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3441 PF11923.3 EGD99702.1 - 0.15 11.6 0.2 0.3 10.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3441) RIO1 PF01163.17 EGD99702.1 - 0.24 10.7 2.5 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family zf-met PF12874.2 EGD99703.1 - 2.1e-05 24.5 0.6 3.8e-05 23.7 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EGD99703.1 - 0.046 12.9 0.9 0.095 11.9 0.6 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Methyltransf_11 PF08241.7 EGD99704.1 - 1.8e-11 44.3 0.0 3.7e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD99704.1 - 4.3e-08 33.5 0.0 7.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD99704.1 - 1.3e-07 32.1 0.0 3.1e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD99704.1 - 2e-07 30.8 0.0 3.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD99704.1 - 0.0037 16.8 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD99704.1 - 0.0054 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD99704.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ERG4_ERG24 PF01222.12 EGD99705.1 - 6e-140 466.5 20.4 6.8e-140 466.4 14.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EGD99705.1 - 0.027 14.5 0.1 0.027 14.5 0.0 3.2 4 0 0 4 4 4 0 Phospholipid methyltransferase MFS_1 PF07690.11 EGD99706.1 - 1.4e-41 142.4 35.4 2.2e-41 141.7 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD99706.1 - 4.7e-11 41.9 10.8 4.7e-11 41.9 7.5 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EGD99706.1 - 2.7e-05 22.7 19.5 0.014 13.8 2.0 3.1 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EGD99706.1 - 0.059 13.1 7.5 0.097 12.4 0.5 3.7 4 0 0 4 4 4 0 MFS_1 like family CAP_GLY PF01302.20 EGD99707.1 - 6.6e-20 70.5 0.1 1.1e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EGD99707.1 - 1.1e-17 63.1 16.1 8.7e-05 22.0 0.4 5.6 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD99707.1 - 2.5e-06 27.1 19.6 0.003 17.2 1.7 4.9 2 1 3 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 EGD99707.1 - 3.8e-06 26.1 19.3 1 9.6 0.0 7.8 5 2 1 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 EGD99707.1 - 0.0006 19.6 14.4 13 6.1 0.0 6.7 6 1 0 6 6 6 2 Leucine Rich repeat LRR_7 PF13504.1 EGD99707.1 - 0.015 15.3 8.7 75 4.2 0.0 6.9 7 0 0 7 7 7 0 Leucine rich repeat LRR_9 PF14580.1 EGD99707.1 - 0.2 11.1 5.1 0.38 10.2 0.2 2.8 2 1 0 3 3 3 0 Leucine-rich repeat zf-U1 PF06220.7 EGD99708.1 - 5.6e-08 32.2 0.5 9.2e-08 31.5 0.4 1.4 1 0 0 1 1 1 1 U1 zinc finger SLY PF12485.3 EGD99708.1 - 0.18 12.0 0.3 0.18 12.0 0.2 2.4 2 1 0 2 2 2 0 Lymphocyte signaling adaptor protein ABC_tran_2 PF12848.2 EGD99708.1 - 4.8 7.0 10.2 2.5 8.0 0.3 2.8 2 1 0 2 2 2 0 ABC transporter Zn_clus PF00172.13 EGD99709.1 - 1.1e-08 34.7 10.4 2e-08 33.9 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 EGD99710.1 - 3.2e-58 195.8 0.0 4.4e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD99710.1 - 6.8e-13 48.2 0.0 7.9e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGD99710.1 - 3.7e-05 23.6 0.0 6.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CwfJ_C_1 PF04677.10 EGD99711.1 - 5.2e-29 100.3 0.0 1e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EGD99711.1 - 8.2e-25 87.1 0.0 3.7e-24 85.0 0.0 2.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 ATP_bind_1 PF03029.12 EGD99712.1 - 4.6e-75 252.2 0.0 6e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EGD99712.1 - 0.00018 20.9 0.0 0.0054 16.1 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGD99712.1 - 0.00025 21.2 0.0 0.00075 19.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGD99712.1 - 0.0004 20.3 0.0 0.0012 18.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 EGD99712.1 - 0.00052 18.8 0.0 0.067 11.9 0.0 2.3 2 0 0 2 2 2 1 ArgK protein SRP54 PF00448.17 EGD99712.1 - 0.00085 18.8 0.0 0.02 14.3 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EGD99712.1 - 0.0012 18.4 0.1 0.0019 17.6 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 EGD99712.1 - 0.0033 17.9 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein CbiA PF01656.18 EGD99712.1 - 0.0034 16.8 0.0 0.01 15.2 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 EGD99712.1 - 0.0044 16.7 0.0 0.0092 15.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain MobB PF03205.9 EGD99712.1 - 0.0046 16.6 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 EGD99712.1 - 0.0052 16.3 0.0 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.13 EGD99712.1 - 0.0055 15.9 0.0 0.098 11.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_33 PF13671.1 EGD99712.1 - 0.0073 16.1 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EGD99712.1 - 0.011 15.1 0.0 0.96 8.8 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EGD99712.1 - 0.015 16.1 0.1 0.13 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGD99712.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EGD99712.1 - 0.023 13.9 0.0 2.2 7.4 0.0 2.8 3 0 0 3 3 3 0 ADP-ribosylation factor family NB-ARC PF00931.17 EGD99712.1 - 0.027 13.3 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EGD99712.1 - 0.038 13.9 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EGD99712.1 - 0.038 14.3 0.0 0.96 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EGD99712.1 - 0.11 11.9 0.1 0.77 9.2 0.0 2.4 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EGD99712.1 - 0.14 12.4 1.3 2.3 8.5 0.0 3.1 3 1 1 4 4 4 0 AAA domain G-alpha PF00503.15 EGD99712.1 - 0.25 9.9 3.5 2.9 6.4 0.0 2.9 3 0 0 3 3 3 0 G-protein alpha subunit BTV_NS2 PF04514.7 EGD99712.1 - 1.8 7.3 5.9 2.6 6.8 4.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 VIT1 PF01988.14 EGD99713.1 - 0.17 11.3 4.6 0.23 10.9 3.2 1.1 1 0 0 1 1 1 0 VIT family GST_N_3 PF13417.1 EGD99714.1 - 2.6e-23 82.0 0.0 5.9e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD99714.1 - 4e-14 52.3 0.0 1e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD99714.1 - 4.8e-06 26.3 0.1 1.1e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD99714.1 - 0.00023 21.2 0.0 0.00059 19.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EGD99714.1 - 0.031 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin SUZ PF12752.2 EGD99715.1 - 0.00055 20.3 5.8 0.0044 17.5 2.2 4.3 4 2 1 5 5 5 2 SUZ domain GRP PF07172.6 EGD99715.1 - 6.4 7.3 12.7 3.4 8.2 6.3 2.1 2 0 0 2 2 2 0 Glycine rich protein family EGL-1 PF11430.3 EGD99716.1 - 0.5 10.0 4.7 0.97 9.1 3.3 1.4 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 Serglycin PF04360.7 EGD99717.1 - 0.028 14.1 0.0 0.086 12.5 0.0 1.7 1 1 0 1 1 1 0 Serglycin F-box-like PF12937.2 EGD99718.1 - 2.2e-05 24.0 0.2 6.1e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGD99718.1 - 3e-05 23.5 14.7 0.1 12.2 0.1 5.6 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGD99718.1 - 0.00021 20.8 8.3 18 5.8 0.0 6.6 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 EGD99718.1 - 0.034 14.3 10.4 52 4.7 0.1 6.8 7 0 0 7 7 7 0 Leucine rich repeat F-box PF00646.28 EGD99718.1 - 0.043 13.4 1.3 0.27 10.9 0.9 2.4 1 1 0 1 1 1 0 F-box domain LRR_6 PF13516.1 EGD99718.1 - 0.074 13.1 13.3 7.9 6.8 0.1 6.2 7 0 0 7 7 7 0 Leucine Rich repeat LRR_8 PF13855.1 EGD99718.1 - 0.077 12.7 14.4 0.2 11.4 0.8 4.8 4 1 0 4 4 4 0 Leucine rich repeat TraF PF13728.1 EGD99718.1 - 0.12 11.8 4.6 0.22 10.9 3.2 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein AA_permease_2 PF13520.1 EGD99721.1 - 2.1e-52 178.0 51.1 2.6e-52 177.8 35.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD99721.1 - 1.2e-25 89.7 46.0 1.7e-25 89.3 31.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.6 EGD99721.1 - 0.9 9.4 9.5 1.6 8.6 0.0 3.9 3 3 0 3 3 3 0 Protein of unknown function (DUF962) p450 PF00067.17 EGD99722.1 - 5.5e-50 170.2 0.0 3.9e-49 167.4 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 APH PF01636.18 EGD99723.1 - 1.5e-13 51.0 0.0 2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD99723.1 - 7.8e-12 45.2 0.0 7.7e-11 41.9 0.0 2.1 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGD99723.1 - 0.015 14.5 0.1 0.37 9.9 0.0 2.3 2 1 0 2 2 2 0 Protein kinase domain BSD PF03909.12 EGD99725.1 - 1.1e-24 85.8 3.8 1.7e-13 50.0 0.6 2.8 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EGD99725.1 - 2.5e-19 68.6 0.1 5.7e-19 67.5 0.1 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain TetR PF13972.1 EGD99725.1 - 0.0072 15.7 0.1 0.047 13.1 0.0 2.2 2 0 0 2 2 2 1 Bacterial transcriptional repressor DUF1751 PF08551.5 EGD99726.1 - 0.00068 19.9 1.5 0.0011 19.2 0.4 1.9 1 1 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) PHD PF00628.24 EGD99727.1 - 9.8e-10 37.9 7.0 1.6e-09 37.3 4.8 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EGD99727.1 - 7.7e-08 32.5 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD_2 PF13831.1 EGD99727.1 - 0.14 11.5 2.8 0.23 10.7 1.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.1 EGD99727.1 - 0.34 11.0 2.0 0.74 10.0 1.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain SIT PF15330.1 EGD99727.1 - 0.63 10.2 3.0 6.5 6.9 0.4 2.8 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Transket_pyr PF02779.19 EGD99728.1 - 2.2e-66 222.7 0.0 3.7e-66 222.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EGD99728.1 - 5.3e-55 186.2 0.0 7.2e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF2247 PF10004.4 EGD99728.1 - 0.019 14.6 0.1 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) DUF1162 PF06650.7 EGD99730.1 - 1.1e-84 283.9 0.0 1.6e-82 276.8 0.0 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EGD99730.1 - 1.4e-41 140.7 0.0 4.1e-41 139.2 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EGD99730.1 - 9.7e-06 25.6 0.2 9.9e-05 22.4 0.0 2.6 2 0 0 2 2 2 1 ATG C terminal domain DUF3429 PF11911.3 EGD99732.1 - 2.3e-40 137.8 11.1 3.5e-40 137.2 7.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_C PF02782.11 EGD99733.1 - 3.3e-70 235.7 0.7 8.2e-70 234.4 0.3 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGD99733.1 - 5.1e-63 212.6 0.0 7.1e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EGD99733.1 - 0.057 12.7 0.3 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.13 EGD99734.1 - 2.6e-62 210.0 0.1 4.6e-62 209.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGD99734.1 - 2.7e-42 144.0 0.0 5.6e-42 143.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGD99734.1 - 1.5e-06 28.3 0.0 2.5e-05 24.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EGD99734.1 - 4e-06 27.6 0.1 1.5e-05 25.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EGD99734.1 - 1.9e-05 24.4 0.0 5.4e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EGD99734.1 - 4.8e-05 22.2 0.0 9.4e-05 21.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 EGD99734.1 - 6.5e-05 23.0 0.2 0.0047 17.0 0.1 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGD99734.1 - 0.00014 20.9 0.1 0.0018 17.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EGD99734.1 - 0.0011 18.4 1.3 0.068 12.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EGD99734.1 - 0.0015 18.5 0.0 0.0048 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EGD99734.1 - 0.0017 17.8 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EGD99734.1 - 0.0024 17.5 0.3 0.0083 15.8 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EGD99734.1 - 0.0026 17.6 0.0 0.008 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD99734.1 - 0.0069 15.5 0.5 0.019 14.0 0.2 1.8 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EGD99734.1 - 0.0083 16.0 0.0 0.03 14.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGD99734.1 - 0.012 15.5 0.2 0.034 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EGD99734.1 - 0.017 14.2 0.3 0.036 13.2 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EGD99734.1 - 0.018 15.3 0.0 0.055 13.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EGD99734.1 - 0.019 14.6 0.3 1.5 8.4 0.1 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.8 EGD99734.1 - 0.021 13.7 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KaiC PF06745.8 EGD99734.1 - 0.042 12.9 0.1 1.4 8.0 0.0 2.6 3 0 0 3 3 3 0 KaiC NTP_transferase PF00483.18 EGD99736.1 - 9.8e-48 162.6 0.0 1.8e-47 161.7 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EGD99736.1 - 3.2e-17 61.1 19.8 3.5e-10 38.9 1.2 4.1 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EGD99736.1 - 1.3e-09 38.3 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EGD99736.1 - 4.9e-07 29.1 1.3 4.9e-07 29.1 0.9 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 EGD99736.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.20 EGD99737.1 - 0.00016 21.6 0.0 0.025 14.4 0.0 3.2 2 1 0 2 2 2 1 short chain dehydrogenase HNH_2 PF13391.1 EGD99740.1 - 7.8e-15 54.4 0.0 2e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Seryl_tRNA_N PF02403.17 EGD99742.1 - 0.012 15.6 1.4 0.015 15.3 1.0 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 EGD99742.1 - 0.013 15.4 6.7 0.21 11.4 4.6 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding HrcA PF01628.16 EGD99742.1 - 0.025 14.1 1.6 0.028 14.0 1.1 1.1 1 0 0 1 1 1 0 HrcA protein C terminal domain DUF1335 PF07056.6 EGD99742.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) Kinesin-relat_1 PF12711.2 EGD99742.1 - 0.21 11.9 3.7 1.1 9.7 0.6 2.3 1 1 1 2 2 2 0 Kinesin motor IncA PF04156.9 EGD99742.1 - 0.44 10.1 6.6 0.49 9.9 4.6 1.1 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 EGD99742.1 - 0.75 9.9 3.0 1.3 9.1 2.0 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.7 EGD99742.1 - 1.1 9.2 3.9 5.4 7.0 0.1 3.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat SlyX PF04102.7 EGD99742.1 - 2.9 8.3 6.2 0.6 10.5 0.4 2.3 1 1 1 2 2 2 0 SlyX FKBP_C PF00254.23 EGD99745.1 - 1.2e-11 44.4 0.0 1.5e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HNH_2 PF13391.1 EGD99746.1 - 1.6e-09 37.4 0.0 3.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Ran_BP1 PF00638.13 EGD99747.1 - 7e-15 55.1 0.1 1.5e-08 34.6 0.1 2.4 2 0 0 2 2 2 2 RanBP1 domain HSP70 PF00012.15 EGD99748.1 - 6.5e-12 44.1 0.0 4.6e-10 38.0 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EGD99748.1 - 0.034 12.7 0.0 0.054 12.0 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein ADIP PF11559.3 EGD99749.1 - 0.00094 19.1 3.0 0.0022 17.9 2.1 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EGD99749.1 - 0.024 14.9 2.0 0.042 14.1 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EGD99749.1 - 0.039 13.7 6.3 1.7 8.5 0.1 2.9 1 1 1 2 2 2 0 Basic region leucine zipper Med9 PF07544.8 EGD99749.1 - 1.9 8.3 5.7 0.78 9.5 1.2 2.3 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Neisseria_TspB PF05616.8 EGD99749.1 - 2.7 6.2 4.9 20 3.4 4.1 1.7 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein IncA PF04156.9 EGD99749.1 - 8.5 5.9 8.6 0.57 9.7 1.7 2.0 2 0 0 2 2 2 0 IncA protein AIG1 PF04548.11 EGD99750.1 - 3.8e-07 29.4 1.0 6.3e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.18 EGD99750.1 - 4.5e-07 29.8 0.2 2.5e-06 27.4 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGD99750.1 - 1.6e-05 24.1 0.0 4.8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EGD99750.1 - 0.0056 15.9 0.0 0.014 14.6 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B IIGP PF05049.8 EGD99750.1 - 0.014 14.2 1.3 0.018 13.9 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 EGD99750.1 - 0.019 14.7 14.7 0.081 12.7 0.0 3.9 2 2 1 3 3 2 0 Dynamin family Viral_helicase1 PF01443.13 EGD99750.1 - 0.02 14.3 0.4 0.063 12.7 0.3 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SRPRB PF09439.5 EGD99750.1 - 0.041 13.1 0.1 0.041 13.1 0.0 2.5 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EGD99750.1 - 0.043 14.3 2.0 0.057 13.9 0.0 2.2 3 0 0 3 3 2 0 Miro-like protein NB-ARC PF00931.17 EGD99750.1 - 0.044 12.6 0.3 0.044 12.6 0.2 2.1 3 1 0 3 3 3 0 NB-ARC domain AAA_22 PF13401.1 EGD99750.1 - 0.057 13.5 0.0 0.057 13.5 0.0 2.5 2 2 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGD99750.1 - 0.072 13.3 0.0 0.072 13.3 0.0 2.7 2 1 0 2 2 1 0 ABC transporter AAA_29 PF13555.1 EGD99750.1 - 0.073 12.6 0.1 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4407 PF14362.1 EGD99750.1 - 0.12 11.2 15.0 0.07 12.0 9.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_33 PF13671.1 EGD99750.1 - 0.21 11.4 2.3 0.28 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGD99750.1 - 0.27 10.6 0.0 0.27 10.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EGD99750.1 - 0.41 10.5 3.6 6.1 6.7 0.0 3.0 2 1 1 3 3 3 0 AAA ATPase domain Gp58 PF07902.6 EGD99750.1 - 0.46 8.6 6.9 0.7 8.0 4.8 1.2 1 0 0 1 1 1 0 gp58-like protein FUSC PF04632.7 EGD99750.1 - 0.76 8.1 2.1 1 7.7 1.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cu-oxidase_3 PF07732.10 EGD99751.1 - 4.1e-44 149.0 0.5 1.2e-42 144.3 0.6 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGD99751.1 - 2.4e-40 137.2 8.7 4.6e-36 123.3 0.0 4.5 3 2 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.17 EGD99751.1 - 5.2e-26 91.4 0.1 1.7e-25 89.7 0.0 1.9 3 0 0 3 3 3 1 Multicopper oxidase Yip1 PF04893.12 EGD99752.1 - 2.9e-13 49.6 16.1 5.1e-13 48.8 11.1 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EGD99752.1 - 0.022 14.4 4.3 0.033 13.8 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) IBR PF01485.16 EGD99753.1 - 0.00073 19.3 6.3 0.00073 19.3 4.4 4.7 5 1 0 5 5 5 2 IBR domain DMA PF03474.9 EGD99753.1 - 0.019 14.8 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif Dicty_REP PF05086.7 EGD99753.1 - 0.39 8.4 0.3 0.54 7.9 0.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein adh_short PF00106.20 EGD99754.1 - 3.8e-58 196.0 4.9 2.7e-29 102.2 0.6 2.3 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EGD99754.1 - 3.1e-30 104.0 0.0 5.8e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EGD99754.1 - 1.1e-25 90.3 1.5 8.3e-12 45.1 0.2 2.4 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EGD99754.1 - 7.4e-16 58.6 2.6 7.8e-08 32.3 0.0 3.1 3 1 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 EGD99754.1 - 9e-05 21.6 0.6 0.015 14.4 0.4 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EGD99754.1 - 0.0074 15.7 2.1 3 7.2 0.5 2.9 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EGD99754.1 - 0.36 10.4 4.8 7.9 6.0 0.1 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thermopsin PF05317.6 EGD99755.1 - 0.016 14.1 0.1 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Thermopsin AAA_14 PF13173.1 EGD99755.1 - 0.02 14.7 0.0 1 9.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 EGD99755.1 - 0.02 13.6 0.1 4.4 6.0 0.0 2.3 2 0 0 2 2 2 0 ArgK protein KAP_NTPase PF07693.9 EGD99755.1 - 0.027 13.4 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain UPF0079 PF02367.12 EGD99755.1 - 0.028 14.0 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Fungal_trans PF04082.13 EGD99757.1 - 4.8e-36 123.9 0.0 3.3e-34 117.9 0.0 2.6 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD99757.1 - 0.0026 17.6 1.0 0.0053 16.6 0.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BLVR PF06375.6 EGD99758.1 - 0.055 13.2 6.0 0.095 12.5 4.2 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) PPDFL PF15060.1 EGD99758.1 - 0.081 12.9 0.1 0.17 11.9 0.0 1.4 2 0 0 2 2 2 0 Differentiation and proliferation regulator U79_P34 PF03064.11 EGD99758.1 - 0.087 12.3 5.6 0.11 11.9 3.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NARP1 PF12569.3 EGD99758.1 - 1.6 7.3 7.0 2 7.0 4.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Hce2 PF14856.1 EGD99759.1 - 3.5e-33 113.3 1.9 8.5e-33 112.1 1.3 1.7 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Glyco_hydro_18 PF00704.23 EGD99759.1 - 1.1e-17 64.5 0.1 1.1e-08 34.9 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 LysM PF01476.15 EGD99759.1 - 0.026 14.3 2.6 0.34 10.8 0.0 3.1 3 0 0 3 3 3 0 LysM domain PigN PF04987.9 EGD99760.1 - 7.5e-162 538.9 25.6 1e-161 538.5 17.8 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EGD99760.1 - 9.2e-12 44.9 0.5 1.8e-10 40.7 0.4 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGD99760.1 - 7.6e-09 35.1 0.0 1.1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EGD99760.1 - 0.003 16.9 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily LolB PF03550.9 EGD99760.1 - 0.067 12.7 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB Csm1 PF12539.3 EGD99761.1 - 1.5e-28 99.0 0.3 9.8e-28 96.4 0.0 2.3 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 MscS_porin PF12795.2 EGD99761.1 - 0.0012 18.2 18.3 0.0012 18.2 12.7 1.7 2 0 0 2 2 1 1 Mechanosensitive ion channel porin domain V_ATPase_I PF01496.14 EGD99761.1 - 0.0027 15.6 3.6 0.0036 15.2 2.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 EGD99761.1 - 0.0035 16.8 11.6 0.0069 15.8 8.0 1.5 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 EGD99761.1 - 0.0046 16.7 18.7 0.014 15.0 13.0 1.9 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 EGD99761.1 - 0.007 15.0 14.6 0.013 14.1 10.1 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Cluap1 PF10234.4 EGD99761.1 - 0.0096 15.1 10.6 0.021 14.0 7.3 1.5 1 0 0 1 1 1 1 Clusterin-associated protein-1 DUF2968 PF11180.3 EGD99761.1 - 0.0099 15.2 13.0 0.021 14.1 9.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Allexi_40kDa PF05549.6 EGD99761.1 - 0.018 14.3 6.5 0.05 12.8 4.5 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein Reo_sigmaC PF04582.7 EGD99761.1 - 0.028 13.5 2.4 0.045 12.9 1.7 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Lge1 PF11488.3 EGD99761.1 - 0.032 14.4 8.5 0.19 11.9 5.7 2.5 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 TBPIP PF07106.8 EGD99761.1 - 0.074 12.5 11.3 0.24 10.9 7.8 1.9 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3450 PF11932.3 EGD99761.1 - 0.11 11.7 13.2 0.21 10.7 9.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Med9 PF07544.8 EGD99761.1 - 0.11 12.2 14.5 0.69 9.6 7.2 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1423 PF07227.6 EGD99761.1 - 0.14 10.7 8.4 0.32 9.5 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Katanin_con80 PF13925.1 EGD99761.1 - 0.16 11.6 4.9 0.28 10.8 3.4 1.3 1 0 0 1 1 1 0 con80 domain of Katanin DUF3138 PF11336.3 EGD99761.1 - 0.18 9.9 7.2 0.34 9.0 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3373 PF11853.3 EGD99761.1 - 0.2 10.1 3.9 0.42 9.0 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Spc42p PF11544.3 EGD99761.1 - 0.21 11.5 12.9 0.038 13.9 3.9 3.1 2 1 1 3 3 2 0 Spindle pole body component Spc42p COG5 PF10392.4 EGD99761.1 - 0.21 11.5 8.7 0.45 10.4 6.1 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 COG6 PF06419.6 EGD99761.1 - 0.47 8.5 13.2 0.63 8.0 9.2 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Fib_alpha PF08702.5 EGD99761.1 - 0.57 10.2 13.1 0.58 10.2 1.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EGD99761.1 - 0.69 9.4 18.8 1.6 8.2 12.5 1.9 1 1 1 2 2 2 0 IncA protein Prominin PF05478.6 EGD99761.1 - 0.77 7.2 4.3 1.1 6.6 3.0 1.2 1 0 0 1 1 1 0 Prominin Cep57_CLD PF14073.1 EGD99761.1 - 0.79 9.5 19.9 0.02 14.7 8.3 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 AAA_13 PF13166.1 EGD99761.1 - 1.1 7.6 20.8 0.045 12.2 7.1 2.1 2 0 0 2 2 2 0 AAA domain DUF607 PF04678.8 EGD99761.1 - 1.1 9.1 4.6 2.6 7.9 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF607 TEX13 PF15186.1 EGD99761.1 - 1.1 8.7 11.8 3.9 7.0 7.4 2.2 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family FUSC PF04632.7 EGD99761.1 - 1.2 7.5 3.9 1.7 6.9 2.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CorA PF01544.13 EGD99761.1 - 1.2 8.0 6.4 2.2 7.2 4.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Macoilin PF09726.4 EGD99761.1 - 1.8 6.7 24.7 2.6 6.2 17.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Baculo_PEP_C PF04513.7 EGD99761.1 - 3.2 7.5 11.0 2.1 8.1 5.9 1.9 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.4 EGD99761.1 - 4.1 7.6 9.2 67 3.7 6.4 2.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF4446 PF14584.1 EGD99761.1 - 4.9 6.9 12.0 6.9 6.4 1.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Atg14 PF10186.4 EGD99761.1 - 5 5.9 20.3 0.99 8.2 9.8 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMPIT PF07851.8 EGD99761.1 - 7.2 5.5 9.2 11 5.0 6.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4200 PF13863.1 EGD99761.1 - 7.4 6.5 22.2 0.27 11.1 10.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA PF00004.24 EGD99762.1 - 2e-37 128.3 0.0 5.2e-37 126.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGD99762.1 - 4.3e-06 26.6 0.0 1.6e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGD99762.1 - 1.5e-05 25.7 0.2 6.8e-05 23.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGD99762.1 - 1.5e-05 24.6 0.3 0.00021 21.0 0.0 2.8 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGD99762.1 - 2.3e-05 24.5 0.1 0.0009 19.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EGD99762.1 - 3.1e-05 23.1 0.0 5.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGD99762.1 - 3.2e-05 23.9 0.8 0.00055 19.9 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.9 EGD99762.1 - 0.00011 22.1 0.0 0.00033 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EGD99762.1 - 0.00021 20.7 0.1 0.028 13.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGD99762.1 - 0.00021 20.7 0.0 0.00046 19.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EGD99762.1 - 0.00037 20.3 0.0 0.00074 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EGD99762.1 - 0.00053 20.0 0.0 0.0018 18.3 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGD99762.1 - 0.0008 18.6 0.1 0.0017 17.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EGD99762.1 - 0.0013 18.9 0.0 0.0041 17.2 0.0 2.1 1 1 1 2 2 1 1 RNA helicase AAA_19 PF13245.1 EGD99762.1 - 0.0018 18.0 0.0 0.024 14.3 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 EGD99762.1 - 0.0023 17.0 0.0 0.0046 16.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EGD99762.1 - 0.0026 17.4 0.0 0.01 15.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 EGD99762.1 - 0.0035 17.3 0.0 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 EGD99762.1 - 0.0037 16.1 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 EGD99762.1 - 0.0056 16.9 0.2 0.016 15.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 EGD99762.1 - 0.0064 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EGD99762.1 - 0.0072 15.8 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_11 PF13086.1 EGD99762.1 - 0.014 14.9 0.2 0.069 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGD99762.1 - 0.023 15.0 0.2 0.073 13.3 0.0 2.0 2 1 0 2 2 2 0 ABC transporter DUF815 PF05673.8 EGD99762.1 - 0.034 13.0 0.0 0.07 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EGD99762.1 - 0.049 12.4 0.2 0.19 10.5 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 EGD99762.1 - 0.051 12.2 0.0 0.083 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein CPT PF07931.7 EGD99762.1 - 0.051 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Arch_ATPase PF01637.13 EGD99762.1 - 0.065 12.9 0.4 0.24 11.0 0.0 2.1 2 1 1 3 3 2 0 Archaeal ATPase TIP49 PF06068.8 EGD99762.1 - 0.077 11.6 0.0 0.29 9.8 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus KaiC PF06745.8 EGD99762.1 - 0.099 11.7 0.0 0.48 9.5 0.0 2.0 1 1 1 2 2 2 0 KaiC UPF0079 PF02367.12 EGD99762.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EGD99762.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cys_Met_Meta_PP PF01053.15 EGD99763.1 - 1.5e-139 464.6 0.0 1.8e-139 464.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGD99763.1 - 0.00011 21.3 0.0 0.00033 19.8 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family SelA PF03841.8 EGD99763.1 - 0.00091 18.0 0.1 0.0021 16.8 0.0 1.5 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.16 EGD99763.1 - 0.0015 17.7 0.0 0.0041 16.3 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase MFS_1 PF07690.11 EGD99764.1 - 2.5e-37 128.4 31.6 4.3e-25 88.1 11.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MTP18 PF10558.4 EGD99766.1 - 2.8e-66 222.0 0.1 4.5e-66 221.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) QRPTase_C PF01729.14 EGD99766.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF2611 PF11022.3 EGD99767.1 - 9.1e-27 92.9 0.4 9.7e-27 92.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) AAT PF03417.11 EGD99768.1 - 3.2e-32 111.7 0.0 4.2e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EGD99768.1 - 2.5e-05 24.5 0.0 5.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase ACPS PF01648.15 EGD99769.1 - 1.4e-18 66.7 0.0 1.8e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily APH PF01636.18 EGD99770.1 - 5.9e-15 55.6 0.0 1.2e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3515 PF12028.3 EGD99770.1 - 0.036 13.3 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) Choline_kinase PF01633.15 EGD99770.1 - 0.06 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EGD99770.1 - 0.065 11.8 0.0 0.17 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Kdo PF06293.9 EGD99770.1 - 0.087 11.8 0.0 2.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EGD99770.1 - 0.092 11.8 0.0 0.41 9.7 0.0 2.0 2 0 0 2 2 2 0 Ecdysteroid kinase F-box PF00646.28 EGD99772.1 - 0.0052 16.4 0.4 0.014 15.0 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD99772.1 - 3 7.6 4.6 0.41 10.3 0.2 1.9 2 0 0 2 2 2 0 F-box-like PHP PF02811.14 EGD99773.1 - 2.9e-07 30.4 0.0 6.3e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 PHP domain IFP_35_N PF07334.8 EGD99773.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus AA_permease PF00324.16 EGD99774.1 - 3.3e-32 111.4 15.2 3.7e-32 111.3 10.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD99774.1 - 6.8e-08 31.4 14.0 7.7e-08 31.2 9.7 1.0 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.11 EGD99774.1 - 0.014 15.7 0.2 0.018 15.3 0.1 1.3 1 1 0 1 1 1 0 Divalent cation transporter EmrE PF13536.1 EGD99774.1 - 0.024 14.8 0.6 0.024 14.8 0.4 2.1 1 1 0 2 2 2 0 Multidrug resistance efflux transporter FKBP_C PF00254.23 EGD99777.1 - 2e-21 75.8 0.0 2.2e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase F-box PF00646.28 EGD99778.1 - 0.0005 19.6 1.4 0.0014 18.2 1.0 1.8 1 0 0 1 1 1 1 F-box domain EAP30 PF04157.11 EGD99780.1 - 4.9e-45 153.4 0.1 6.5e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EGD99780.1 - 7.5e-25 86.5 0.0 1.5e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 EGD99780.1 - 0.00012 21.5 6.4 0.00048 19.6 0.2 3.4 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 EGD99780.1 - 0.0015 17.6 9.5 0.0034 16.4 0.2 2.8 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 EGD99780.1 - 0.0052 16.2 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Cas_CXXC_CXXC PF09706.5 EGD99780.1 - 0.037 14.1 0.2 3.9 7.7 0.0 2.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-MIZ PF02891.15 EGD99780.1 - 0.087 12.3 0.1 0.087 12.3 0.1 1.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DZR PF12773.2 EGD99780.1 - 3.3 7.5 7.6 2.3 8.1 1.2 2.5 1 1 2 3 3 3 0 Double zinc ribbon SAC3_GANP PF03399.11 EGD99781.1 - 1.3e-30 106.5 0.8 1.2e-25 90.2 0.1 2.4 1 1 1 2 2 2 2 SAC3/GANP/Nin1/mts3/eIF-3 p25 family LLC1 PF14945.1 EGD99781.1 - 1.3 9.3 6.5 20 5.5 0.0 3.6 2 1 0 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein SH3_1 PF00018.23 EGD99782.1 - 2.6e-25 87.5 1.3 2.1e-11 43.0 0.0 3.3 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 EGD99782.1 - 4.7e-15 54.9 2.2 1.5e-06 27.6 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 EGD99782.1 - 1.3e-13 50.7 0.0 2.4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EGD99782.1 - 7.4e-12 44.5 0.6 8.8e-07 28.3 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.19 EGD99782.1 - 8.7e-07 28.5 0.4 1.7e-06 27.6 0.3 1.4 1 0 0 1 1 1 1 PB1 domain AFG1_ATPase PF03969.11 EGD99783.1 - 8.9e-93 310.9 0.0 3.6e-87 292.5 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EGD99783.1 - 0.00014 21.9 0.8 0.64 9.9 0.0 3.6 2 2 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 EGD99783.1 - 0.0025 17.6 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EGD99783.1 - 0.0039 17.3 0.0 0.017 15.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EGD99783.1 - 0.13 11.3 0.0 0.53 9.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EGD99783.1 - 0.14 12.3 0.0 0.63 10.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain Chitin_synth_1 PF01644.12 EGD99784.1 - 3.6e-77 257.7 0.0 7.9e-77 256.6 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EGD99784.1 - 9.6e-23 80.3 3.0 3.7e-21 75.1 0.0 2.1 1 1 1 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.6 EGD99784.1 - 3e-08 33.2 0.0 7.7e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EGD99784.1 - 4.4e-08 33.0 0.3 4.4e-08 33.0 0.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGD99784.1 - 5.7e-05 23.0 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 dCMP_cyt_deam_1 PF00383.17 EGD99785.1 - 6.2e-08 32.2 0.0 8e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF1774 PF08611.5 EGD99786.1 - 1.2e-33 115.1 1.6 1.2e-33 115.1 1.1 2.0 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Glyco_transf_54 PF04666.8 EGD99786.1 - 0.019 13.6 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Peptidase_M28 PF04389.12 EGD99787.1 - 2e-23 83.0 0.0 4.2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 R3H-assoc PF13902.1 EGD99788.1 - 7.3e-32 110.0 10.5 1.5e-31 109.0 7.3 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 EGD99788.1 - 0.0058 16.3 0.0 0.016 14.8 0.0 1.8 1 0 0 1 1 1 1 R3H domain STAT_int PF02865.12 EGD99788.1 - 0.11 12.4 1.2 0.26 11.2 0.6 1.7 1 1 0 1 1 1 0 STAT protein, protein interaction domain Hist_deacetyl PF00850.14 EGD99789.1 - 2.6e-58 197.7 0.1 4.5e-58 196.9 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain zf-AN1 PF01428.11 EGD99790.1 - 7.1e-24 83.4 22.5 5.2e-13 48.6 5.7 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EGD99790.1 - 0.012 15.4 3.3 0.012 15.4 2.3 3.1 2 1 0 2 2 2 0 IBR domain Transp_Tc5_C PF04236.10 EGD99790.1 - 0.17 12.1 17.2 0.35 11.1 3.1 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain C1_1 PF00130.17 EGD99790.1 - 6.8 6.5 13.2 0.32 10.7 1.4 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Thymidylat_synt PF00303.14 EGD99791.1 - 5.8e-111 369.8 0.0 6.6e-111 369.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase TGT PF01702.13 EGD99792.1 - 3.5e-91 304.7 0.0 4.6e-91 304.3 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Fungal_trans PF04082.13 EGD99793.1 - 3.4e-20 72.0 0.1 8e-20 70.8 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD99793.1 - 8.7e-10 38.3 12.7 2.1e-09 37.1 8.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FGF-BP1 PF06473.7 EGD99793.1 - 0.0049 16.4 1.5 0.0084 15.7 1.1 1.3 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) DUF2360 PF10152.4 EGD99793.1 - 3.8 7.7 6.3 9.9 6.4 4.4 1.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DND1_DSRM PF14709.1 EGD99794.1 - 0.00059 20.0 0.0 0.00094 19.4 0.0 1.3 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 MGC-24 PF05283.6 EGD99796.1 - 0.11 12.2 6.1 0.13 12.0 4.2 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Glyco_hydro_18 PF00704.23 EGD99797.1 - 3.1e-62 211.0 0.1 5.5e-62 210.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Interferon PF00143.14 EGD99797.1 - 0.24 11.2 0.1 0.45 10.3 0.0 1.4 1 0 0 1 1 1 0 Interferon alpha/beta domain Metallophos PF00149.23 EGD99798.1 - 1.2e-10 41.0 8.2 2.5e-10 40.0 5.7 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD99798.1 - 1.5e-05 24.9 0.1 2.1e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Acyltransferase PF01553.16 EGD99798.1 - 0.11 11.8 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Acyltransferase ARGLU PF15346.1 EGD99799.1 - 0.06 13.1 16.1 0.15 11.8 11.2 1.6 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 U79_P34 PF03064.11 EGD99799.1 - 7.7 5.9 12.2 11 5.4 7.5 1.8 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Ala_racemase_N PF01168.15 EGD99801.1 - 3.5e-40 137.8 0.0 4.6e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 EGD99802.1 - 6.8e-124 414.0 4.8 8.9e-124 413.6 3.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EGD99802.1 - 3.2e-40 136.6 0.0 8e-40 135.3 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EGD99802.1 - 7.6e-18 64.9 0.1 3e-17 62.9 0.0 2.1 3 0 0 3 3 3 1 Adaptin C-terminal domain Homeobox PF00046.24 EGD99804.1 - 1.1e-16 60.1 3.2 2.1e-16 59.2 2.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EGD99804.1 - 0.042 13.5 0.2 0.098 12.3 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain efThoc1 PF11957.3 EGD99807.1 - 6.9e-173 575.6 5.3 8e-173 575.4 3.6 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor AAA_12 PF13087.1 EGD99808.1 - 2.3e-25 89.1 0.0 3.9e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGD99808.1 - 5.5e-24 85.0 0.0 9.8e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGD99808.1 - 1.2e-09 37.8 0.0 6.9e-09 35.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EGD99808.1 - 3.2e-06 26.8 0.0 0.00052 19.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EGD99808.1 - 0.0003 20.6 0.0 0.00059 19.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EGD99808.1 - 0.00034 20.2 0.1 0.33 10.4 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EGD99808.1 - 0.0015 17.8 0.1 0.0051 16.1 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EGD99808.1 - 0.0022 17.5 0.1 0.031 13.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA PF00004.24 EGD99808.1 - 0.0033 17.6 0.0 0.012 15.7 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGD99808.1 - 0.0045 16.4 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGD99808.1 - 0.0059 16.7 0.0 0.02 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.9 EGD99808.1 - 0.0062 15.5 0.0 0.64 8.9 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_16 PF13191.1 EGD99808.1 - 0.0077 16.2 0.2 0.029 14.3 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EGD99808.1 - 0.02 14.6 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 EGD99808.1 - 0.025 13.7 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EGD99808.1 - 0.026 13.4 0.5 0.053 12.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 EGD99808.1 - 0.039 12.8 0.0 0.08 11.8 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NB-ARC PF00931.17 EGD99808.1 - 0.041 12.7 0.0 0.098 11.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 EGD99808.1 - 0.047 13.4 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGD99808.1 - 0.063 13.1 0.1 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGD99808.1 - 0.09 13.6 0.2 7 7.5 0.1 3.7 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 EGD99808.1 - 0.15 11.5 0.1 0.49 9.8 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.10 EGD99808.1 - 0.2 10.2 0.1 0.46 9.0 0.1 1.5 1 0 0 1 1 1 0 Adenovirus IVa2 protein 4HBT PF03061.17 EGD99809.1 - 0.0003 20.8 0.1 0.0083 16.2 0.0 2.3 1 1 1 2 2 2 2 Thioesterase superfamily DUF4442 PF14539.1 EGD99809.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) APH PF01636.18 EGD99811.1 - 2.2e-15 57.0 0.4 3.3e-15 56.4 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EGD99811.1 - 0.01 14.8 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase tRNA-synt_1b PF00579.20 EGD99812.1 - 9.4e-25 87.3 0.0 1.5e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) 14-3-3 PF00244.15 EGD99813.1 - 2e-10 40.1 0.1 3.5e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 14-3-3 protein Acyl-CoA_dh_1 PF00441.19 EGD99814.1 - 4.5e-33 114.4 0.5 6.4e-33 113.9 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGD99814.1 - 6.3e-21 73.6 0.9 1e-20 72.9 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EGD99814.1 - 1.8e-11 44.6 0.6 5.6e-11 43.0 0.1 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGD99814.1 - 1.2e-06 28.8 0.1 1.7e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.13 EGD99815.1 - 1.8e-17 63.0 0.2 3e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD99815.1 - 5.2e-05 23.0 11.0 0.0001 22.1 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAR9 PF08580.5 EGD99815.1 - 4.4 5.4 8.7 6.6 4.8 6.0 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 HpcH_HpaI PF03328.9 EGD99816.1 - 1.3e-34 119.0 0.0 1.6e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 EGD99816.1 - 0.0041 16.3 0.2 0.83 8.8 0.0 2.6 2 0 0 2 2 2 2 Phosphoenolpyruvate phosphomutase CHORD PF04968.7 EGD99817.1 - 4.4e-52 174.1 18.0 7.4e-26 90.1 3.6 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EGD99817.1 - 1.9e-13 50.7 0.1 3e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 CS domain MGC-24 PF05283.6 EGD99817.1 - 5.7 6.6 10.4 10 5.8 7.2 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Choline_kinase PF01633.15 EGD99818.1 - 1.9e-45 155.0 0.0 2.3e-44 151.5 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EGD99818.1 - 1.3e-09 38.2 0.9 2.4e-09 37.2 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Voldacs PF03517.8 EGD99819.1 - 0.0049 16.7 3.2 0.0064 16.3 2.2 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Sod_Cu PF00080.15 EGD99820.1 - 1.9e-15 57.2 0.0 3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF3405 PF11885.3 EGD99822.1 - 1e-217 723.3 0.7 1.2e-217 723.0 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) CCDC155 PF14662.1 EGD99824.1 - 0.032 13.8 0.2 0.041 13.4 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Arf PF00025.16 EGD99827.1 - 2.3e-79 264.6 0.1 2.6e-79 264.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGD99827.1 - 6.4e-15 54.8 0.0 7.9e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGD99827.1 - 2.6e-13 49.6 0.0 2.9e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EGD99827.1 - 1.9e-12 46.5 1.7 2e-09 36.6 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGD99827.1 - 4.9e-11 42.2 0.0 5.7e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGD99827.1 - 3e-08 34.1 0.0 4.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGD99827.1 - 3.8e-06 26.8 0.0 5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EGD99827.1 - 0.0078 15.3 0.4 0.02 13.9 0.1 1.6 1 1 1 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EGD99827.1 - 0.011 15.1 0.1 0.096 12.1 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EGD99827.1 - 0.043 13.7 0.2 0.12 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.19 EGD99828.1 - 1.5e-12 47.3 0.0 2.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGD99828.1 - 3.8e-08 33.4 0.0 1e-06 28.8 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD99828.1 - 1.8e-06 27.6 0.0 1.4e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 EGD99828.1 - 3.2e-05 23.9 0.0 5.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGD99828.1 - 4.8e-05 23.5 0.0 6.3e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD99828.1 - 0.057 13.2 0.1 0.41 10.4 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGD99828.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGD99828.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD99828.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ribosomal_L1 PF00687.16 EGD99829.1 - 4.9e-53 179.7 0.4 5.9e-53 179.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family WH2 PF02205.15 EGD99831.1 - 5.4e-10 38.5 0.4 5.4e-10 38.5 0.3 1.9 2 0 0 2 2 2 1 WH2 motif LSM PF01423.17 EGD99832.1 - 4.1e-17 61.4 0.1 5.4e-17 61.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain SURF4 PF02077.10 EGD99834.1 - 5.7e-94 314.4 7.0 6.5e-94 314.2 4.9 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.8 EGD99834.1 - 0.084 12.4 0.2 0.22 11.0 0.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) DoxX PF07681.7 EGD99834.1 - 0.96 9.9 21.7 0.11 12.8 3.3 3.0 3 2 0 3 3 3 0 DoxX Amidase PF01425.16 EGD99837.1 - 4.3e-91 305.9 0.0 5e-91 305.7 0.0 1.0 1 0 0 1 1 1 1 Amidase Glycos_transf_1 PF00534.15 EGD99838.1 - 4.5e-13 48.9 0.0 8.2e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGD99838.1 - 0.00076 19.6 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGD99838.1 - 0.028 14.6 0.1 0.086 13.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 HLH PF00010.21 EGD99840.1 - 2.2e-12 46.4 0.5 7.7e-12 44.7 0.3 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mitofilin PF09731.4 EGD99840.1 - 0.03 13.0 10.4 0.035 12.7 7.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF605 PF04652.11 EGD99840.1 - 0.1 11.9 18.7 0.009 15.4 9.7 1.6 2 0 0 2 2 2 0 Vta1 like FCP1_C PF09309.5 EGD99840.1 - 0.47 9.7 12.8 1.2 8.3 8.7 1.9 2 1 0 2 2 2 0 FCP1, C-terminal PAT1 PF09770.4 EGD99840.1 - 1.3 7.2 30.2 1.7 6.7 20.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 EGD99840.1 - 3.2 6.0 11.1 4.5 5.5 7.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex16 PF08610.5 EGD99840.1 - 3.9 6.3 9.6 6.2 5.7 6.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DivIC PF04977.10 EGD99840.1 - 3.9 7.0 8.9 2.7 7.5 4.3 2.1 2 0 0 2 2 2 0 Septum formation initiator IU_nuc_hydro PF01156.14 EGD99841.1 - 1.9e-55 188.3 1.2 3.6e-54 184.1 0.8 2.0 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.15 EGD99841.1 - 0.0007 19.5 0.1 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 Transketolase, C-terminal domain AF1Q PF15017.1 EGD99841.1 - 0.011 15.6 1.4 0.017 15.0 0.1 1.9 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator DUF1305 PF06996.6 EGD99841.1 - 0.062 12.3 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1305) DUF834 PF05754.9 EGD99842.1 - 0.03 14.1 0.9 0.061 13.1 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF834) Fungal_trans PF04082.13 EGD99843.1 - 5.3e-19 68.1 1.7 7.4e-19 67.6 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD99843.1 - 5.8e-08 32.5 9.2 1.3e-07 31.4 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIP_1 PF08995.5 EGD99843.1 - 0.14 12.3 4.4 27 5.0 0.0 2.7 2 1 1 3 3 3 0 Necrosis inducing protein-1 p450 PF00067.17 EGD99844.1 - 5.6e-39 133.9 0.0 7.5e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FA_hydroxylase PF04116.8 EGD99845.1 - 2e-11 44.3 15.1 2e-11 44.3 10.5 2.9 2 2 1 3 3 3 1 Fatty acid hydroxylase superfamily HemY_N PF07219.8 EGD99845.1 - 0.84 9.2 2.7 0.38 10.3 0.3 1.5 2 0 0 2 2 2 0 HemY protein N-terminus Arylsulfotran_2 PF14269.1 EGD99846.1 - 2.7e-109 364.9 1.1 3.9e-109 364.4 0.7 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) p450 PF00067.17 EGD99847.1 - 3.5e-57 193.9 0.0 4.6e-55 186.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.17 EGD99848.1 - 1.8e-39 135.5 10.9 2.7e-39 135.0 7.5 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD99848.1 - 3.6e-14 53.0 0.0 7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_M14 PF00246.19 EGD99850.1 - 2.1e-78 263.7 0.2 6.8e-78 262.0 0.0 1.7 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EGD99850.1 - 3.6e-12 45.7 0.1 7.5e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide AstE_AspA PF04952.9 EGD99850.1 - 0.037 12.9 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Fungal_trans PF04082.13 EGD99851.1 - 1.3e-17 63.5 0.0 2.5e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD99851.1 - 4.9e-08 32.7 13.0 1e-07 31.7 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rox3 PF08633.5 EGD99852.1 - 6.5e-51 173.3 0.1 1.1e-50 172.7 0.1 1.3 1 0 0 1 1 1 1 Rox3 mediator complex subunit HAD_2 PF13419.1 EGD99853.1 - 4.7e-33 114.8 0.0 6.2e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGD99853.1 - 0.033 14.5 0.0 0.061 13.7 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Thr_synth_N PF14821.1 EGD99854.1 - 6.6e-28 96.5 0.0 2.5e-27 94.7 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 EGD99854.1 - 1.6e-16 60.4 0.0 3.7e-16 59.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4202 PF13875.1 EGD99855.1 - 1.3e-74 249.8 1.8 1.4e-74 249.7 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) VIT1 PF01988.14 EGD99856.1 - 6.7e-57 192.4 4.3 7.8e-57 192.1 3.0 1.0 1 0 0 1 1 1 1 VIT family 7TMR-DISM_7TM PF07695.6 EGD99856.1 - 0.0011 18.6 0.5 0.0017 18.0 0.4 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling SOG2 PF10428.4 EGD99857.1 - 0.81 8.2 3.5 0.85 8.1 2.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein AAA_assoc PF14363.1 EGD99858.1 - 0.1 12.6 0.1 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA VPS9 PF02204.13 EGD99859.1 - 1.4e-31 108.5 0.1 2.7e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EGD99859.1 - 6.4e-09 35.1 0.2 2.1e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 CUE domain Asn_synthase PF00733.16 EGD99860.1 - 1.3e-34 119.8 0.0 1.9e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGD99860.1 - 2.5e-07 30.4 0.0 5.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGD99860.1 - 0.0014 18.5 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EGD99860.1 - 0.0015 17.7 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein bZIP_1 PF00170.16 EGD99861.1 - 3.7e-13 49.2 4.0 7.1e-13 48.3 2.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGD99861.1 - 1.7e-07 30.9 8.0 4.2e-07 29.6 5.5 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Sugarporin_N PF11471.3 EGD99861.1 - 0.005 16.4 3.2 0.013 15.1 2.2 1.6 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension bZIP_Maf PF03131.12 EGD99861.1 - 0.021 15.1 7.1 0.062 13.5 4.9 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor PNTB PF02233.11 EGD99862.1 - 2.7e-158 527.5 26.2 9.2e-154 512.6 18.2 2.6 3 0 0 3 3 3 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EGD99862.1 - 1.5e-48 164.5 0.5 3.1e-48 163.5 0.4 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EGD99862.1 - 2.2e-34 118.3 0.0 6.1e-34 116.9 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EGD99862.1 - 4.4e-31 106.9 3.4 4.4e-31 106.9 2.4 5.1 4 2 1 6 6 6 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EGD99862.1 - 0.0008 18.6 0.9 1.8 7.6 0.0 3.4 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EGD99862.1 - 0.035 13.9 0.5 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.17 EGD99862.1 - 0.067 12.9 0.7 0.62 9.8 0.3 2.8 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Methyltransf_18 PF12847.2 EGD99862.1 - 0.12 12.9 0.0 0.38 11.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGD99862.1 - 0.14 11.7 0.0 0.52 9.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Shikimate_DH PF01488.15 EGD99862.1 - 0.56 10.3 4.6 42 4.2 0.0 4.2 5 0 0 5 5 5 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 EGD99862.1 - 1.7 8.6 6.6 0.77 9.8 1.1 3.2 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PH_6 PF15406.1 EGD99863.1 - 5.4e-32 110.1 1.1 5.4e-32 110.1 0.8 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 EGD99863.1 - 7.4e-06 26.1 0.0 2.5e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 PH domain Sulfate_transp PF00916.15 EGD99865.1 - 3.7e-42 144.2 7.6 3.7e-42 144.2 5.3 1.8 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EGD99865.1 - 4.2e-15 55.3 0.0 1e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EGD99865.1 - 1.1e-11 44.1 0.1 2e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.6 EGD99867.1 - 2.2e-13 50.4 0.4 4.5e-13 49.4 0.1 1.5 1 1 1 2 2 2 1 GINS complex protein DUF1876 PF08962.6 EGD99867.1 - 0.11 12.2 0.3 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) HMG_box PF00505.14 EGD99868.1 - 1.2e-09 38.3 0.4 1.2e-09 38.3 0.3 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box PHD PF00628.24 EGD99871.1 - 5.6e-09 35.5 12.4 2.6e-08 33.4 7.4 2.4 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EGD99871.1 - 0.0035 16.6 6.2 0.0035 16.6 4.3 2.2 2 0 0 2 2 2 1 PHD-finger DDRGK PF09756.4 EGD99871.1 - 0.97 8.8 35.7 2.6 7.4 22.5 2.3 2 0 0 2 2 2 0 DDRGK domain DUF2252 PF10009.4 EGD99871.1 - 2.3 7.0 15.4 16 4.2 10.7 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Rcd1 PF04078.8 EGD99872.1 - 8.4e-131 434.5 2.9 1e-130 434.2 2.0 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Spore-coat_CotD PF11122.3 EGD99872.1 - 0.77 10.1 10.8 2.7 8.3 7.5 1.9 1 1 0 1 1 1 0 Inner spore coat protein D PAT1 PF09770.4 EGD99872.1 - 2.1 6.4 12.9 2.5 6.2 8.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CENP-U PF13097.1 EGD99872.1 - 2.8 7.8 8.2 4.8 7.0 5.7 1.3 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Mucin PF01456.12 EGD99874.1 - 0.11 12.2 19.5 0.18 11.5 13.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.3 EGD99874.1 - 1.5 7.9 11.5 1.8 7.7 8.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mito_carr PF00153.22 EGD99876.1 - 2e-56 187.7 1.3 1.1e-19 69.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EpsG PF14897.1 EGD99876.1 - 0.22 10.4 0.1 3.8 6.3 0.0 2.1 2 0 0 2 2 2 0 EpsG family DUF508 PF04370.7 EGD99876.1 - 3 7.4 9.3 0.22 11.1 2.5 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF508) PIN_2 PF10130.4 EGD99877.1 - 2.4 8.1 10.3 0.66 10.0 3.0 2.8 2 1 0 2 2 2 0 PIN domain Prefoldin_2 PF01920.15 EGD99879.1 - 6.7e-21 74.0 4.6 7.7e-21 73.8 3.0 1.2 1 1 0 1 1 1 1 Prefoldin subunit TPR_MLP1_2 PF07926.7 EGD99879.1 - 0.0017 18.1 1.2 0.0026 17.4 0.9 1.3 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 EGD99879.1 - 0.012 15.7 2.9 0.091 12.9 0.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2681 PF10883.3 EGD99879.1 - 0.024 14.8 6.9 0.18 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Jnk-SapK_ap_N PF09744.4 EGD99879.1 - 0.027 14.4 0.4 0.027 14.4 0.3 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.5 EGD99879.1 - 0.028 14.5 7.3 0.44 10.6 0.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Val_tRNA-synt_C PF10458.4 EGD99879.1 - 0.037 14.1 3.9 0.038 14.0 0.2 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Lzipper-MIP1 PF14389.1 EGD99879.1 - 0.051 13.6 0.1 0.051 13.6 0.1 1.9 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Cast PF10174.4 EGD99879.1 - 0.063 11.3 7.1 0.15 10.0 0.5 2.0 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone HALZ PF02183.13 EGD99879.1 - 0.1 12.3 2.9 0.38 10.5 0.2 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Uds1 PF15456.1 EGD99879.1 - 0.12 12.3 4.3 0.19 11.7 0.6 2.1 2 0 0 2 2 2 0 Up-regulated During Septation PspA_IM30 PF04012.7 EGD99879.1 - 0.17 11.2 8.1 1.3 8.3 1.4 2.1 2 0 0 2 2 2 0 PspA/IM30 family TMF_TATA_bd PF12325.3 EGD99879.1 - 0.19 11.4 5.9 0.23 11.1 0.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tektin PF03148.9 EGD99879.1 - 0.23 9.9 6.0 0.18 10.3 0.2 2.0 2 0 0 2 2 2 0 Tektin family Snf7 PF03357.16 EGD99879.1 - 0.25 10.7 5.1 3.1 7.1 0.3 2.1 2 0 0 2 2 2 0 Snf7 Spc24 PF08286.6 EGD99879.1 - 0.27 10.9 5.1 2.7 7.7 0.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Microtub_assoc PF07989.6 EGD99879.1 - 0.29 11.0 4.6 0.16 11.8 0.4 2.2 2 0 0 2 2 2 0 Microtubule associated DUF4618 PF15397.1 EGD99879.1 - 0.29 10.4 5.5 0.97 8.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) WEMBL PF05701.6 EGD99879.1 - 0.32 9.4 6.1 0.52 8.7 4.3 1.3 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Prefoldin PF02996.12 EGD99879.1 - 0.32 10.6 6.7 1.6 8.4 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF4140 PF13600.1 EGD99879.1 - 0.38 11.2 5.2 12 6.4 1.4 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MscS_porin PF12795.2 EGD99879.1 - 0.39 9.9 9.2 2.1 7.6 3.1 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ADIP PF11559.3 EGD99879.1 - 0.62 9.9 7.0 2.8 7.8 0.7 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 EGD99879.1 - 1.3 9.0 6.8 0.65 10.0 0.5 2.1 2 0 0 2 2 2 0 DivIVA protein RasGAP_C PF03836.10 EGD99879.1 - 1.4 8.6 6.6 0.44 10.2 1.1 2.0 1 1 1 2 2 2 0 RasGAP C-terminus ATG16 PF08614.6 EGD99879.1 - 1.5 8.5 8.3 3 7.6 1.5 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 EGD99879.1 - 1.8 8.0 8.0 3.1 7.3 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 EGD99879.1 - 2 8.8 8.7 0.83 10.0 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 EGD99879.1 - 2.3 8.6 6.9 21 5.5 0.1 2.3 2 0 0 2 2 2 0 SlyX APG6 PF04111.7 EGD99879.1 - 2.6 7.0 6.0 11 4.9 4.2 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF1664 PF07889.7 EGD99879.1 - 2.9 7.7 6.6 1.1 9.0 0.5 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) USP8_interact PF08941.5 EGD99879.1 - 3.3 6.9 5.3 1.6 8.0 1.7 1.8 1 1 1 2 2 2 0 USP8 interacting Fzo_mitofusin PF04799.8 EGD99879.1 - 3.9 6.8 6.0 0.73 9.1 0.4 1.9 1 1 0 2 2 2 0 fzo-like conserved region IncA PF04156.9 EGD99879.1 - 4.5 6.8 8.9 38 3.7 6.2 1.9 1 1 0 1 1 1 0 IncA protein TBPIP PF07106.8 EGD99879.1 - 5.2 6.5 9.4 16 4.9 4.2 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) THOC7 PF05615.8 EGD99879.1 - 5.5 7.2 8.3 11 6.2 0.7 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 Toprim PF01751.17 EGD99880.1 - 2.9e-05 23.9 0.0 8.2e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Toprim domain GMC_oxred_N PF00732.14 EGD99881.1 - 6.5e-46 156.8 0.6 9.6e-46 156.2 0.4 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGD99881.1 - 1.2e-28 100.1 0.5 8.4e-28 97.4 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EGD99881.1 - 1.2e-07 30.9 0.3 2.9e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EGD99881.1 - 0.00049 20.0 0.4 0.0011 18.9 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD99881.1 - 0.00057 18.8 9.1 0.011 14.7 6.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGD99881.1 - 0.00061 18.9 0.5 0.0018 17.4 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EGD99881.1 - 0.0046 16.9 1.8 0.012 15.6 0.4 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EGD99881.1 - 0.0056 15.7 0.3 0.0095 15.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EGD99881.1 - 0.069 12.2 0.5 0.1 11.6 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TCTP PF00838.12 EGD99882.1 - 9.2e-60 201.3 1.5 1e-59 201.2 1.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein ISG65-75 PF11727.3 EGD99882.1 - 0.0081 15.2 1.0 0.01 14.9 0.7 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein Hypoth_Ymh PF09509.5 EGD99882.1 - 0.042 13.4 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) SRP19 PF01922.12 EGD99883.1 - 1e-28 99.7 0.0 1.8e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein PG_binding_1 PF01471.13 EGD99883.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Fungal_trans PF04082.13 EGD99884.1 - 1.9e-17 62.9 0.0 4.1e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD99884.1 - 2.2e-10 40.2 8.6 4.2e-10 39.3 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HNH_2 PF13391.1 EGD99885.1 - 3.5e-08 33.1 0.3 1.2e-07 31.4 0.1 2.0 2 0 0 2 2 2 1 HNH endonuclease BCS1_N PF08740.6 EGD99886.1 - 4.2e-49 166.7 0.5 6.7e-49 166.0 0.3 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGD99886.1 - 1.8e-16 60.5 0.0 3.7e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGD99886.1 - 0.00077 20.2 0.7 0.0026 18.5 0.0 2.2 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 EGD99886.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGD99886.1 - 0.009 16.0 0.1 0.051 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EGD99886.1 - 0.016 14.9 0.0 0.078 12.7 0.0 2.1 1 1 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EGD99886.1 - 0.046 13.1 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Polyoma_lg_T_C PF06431.6 EGD99886.1 - 0.057 12.0 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus KaiC PF06745.8 EGD99886.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 EGD99886.1 - 0.086 13.1 0.4 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain PBP1_TM PF14812.1 EGD99886.1 - 4.5 7.6 9.7 7.1 7.0 0.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FA_hydroxylase PF04116.8 EGD99888.1 - 7.5e-18 64.9 11.9 7.5e-18 64.9 8.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily UNC-79 PF14776.1 EGD99888.1 - 0.01 14.2 0.1 0.016 13.6 0.0 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Aldo_ket_red PF00248.16 EGD99889.1 - 1.7e-54 184.5 0.0 1.9e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Kelch_5 PF13854.1 EGD99890.1 - 1.5e-10 40.7 0.5 1.5e-10 40.7 0.3 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 EGD99890.1 - 5.3e-06 25.8 1.7 0.24 11.0 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 EGD99890.1 - 5.6e-06 26.0 4.5 0.00074 19.2 0.1 4.4 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 EGD99890.1 - 1.3e-05 25.2 2.0 0.00039 20.4 0.1 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EGD99890.1 - 0.0025 17.9 4.0 0.023 14.8 0.1 4.1 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 EGD99890.1 - 0.021 14.5 0.2 7.7 6.4 0.1 4.0 4 0 0 4 4 4 0 Kelch motif BatA PF07584.6 EGD99890.1 - 0.16 12.1 0.1 0.3 11.3 0.1 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF4002 PF13164.1 EGD99895.1 - 0.38 10.7 19.6 0.54 10.2 13.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4002) Pyr_redox_3 PF13738.1 EGD99897.1 - 0.00011 22.3 0.0 0.00034 20.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Abhydro_lipase PF04083.11 EGD99897.1 - 0.092 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region K_oxygenase PF13434.1 EGD99897.1 - 0.13 11.1 0.0 0.97 8.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pkinase PF00069.20 EGD99898.1 - 1.8e-17 63.3 0.0 1.7e-16 60.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD99898.1 - 5.9e-06 25.5 0.0 0.076 12.0 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EGD99898.1 - 0.011 15.4 0.2 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3700 PF12481.3 EGD99899.1 - 0.0018 17.4 0.4 0.75 8.9 0.0 2.1 2 0 0 2 2 2 2 Aluminium induced protein Arf PF00025.16 EGD99900.1 - 6.8e-39 132.8 0.0 2.6e-25 88.6 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EGD99900.1 - 7.5e-12 44.6 0.0 3e-05 22.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EGD99900.1 - 3.2e-08 33.1 0.0 0.0002 20.7 0.0 2.2 2 0 0 2 2 2 2 Ras family GTP_EFTU PF00009.22 EGD99900.1 - 8.2e-08 31.8 0.0 4.7e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGD99900.1 - 1.4e-07 30.8 0.0 2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGD99900.1 - 1.7e-07 31.2 0.0 8.6e-06 25.7 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EGD99900.1 - 1.7e-07 31.7 0.0 2e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EGD99900.1 - 3.9e-06 26.2 0.0 2.2e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EGD99900.1 - 0.004 16.6 0.0 0.021 14.3 0.1 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EGD99900.1 - 0.014 14.6 0.0 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B PIGA PF08288.7 EGD99901.1 - 5.1e-46 154.9 1.5 5.1e-46 154.9 1.0 1.7 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EGD99901.1 - 6.9e-29 100.4 0.0 1.1e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGD99901.1 - 3.3e-16 59.4 0.7 6.6e-16 58.5 0.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EGD99901.1 - 1.2e-13 51.3 0.0 2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGD99901.1 - 2.8e-13 50.3 0.0 4.4e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EGD99901.1 - 2.8e-06 27.2 0.2 5.2e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EGD99901.1 - 0.0012 19.0 0.0 0.0032 17.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 DEAD PF00270.24 EGD99902.1 - 1.7e-35 122.0 0.0 2.2e-17 63.0 0.0 3.0 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD99902.1 - 1.7e-16 59.8 0.1 4e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD99902.1 - 3.1e-07 30.4 1.2 9.2e-07 28.8 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EGD99902.1 - 0.033 12.6 0.0 1.2 7.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) AAA_19 PF13245.1 EGD99902.1 - 0.091 12.5 1.2 3.4 7.4 0.5 2.8 2 0 0 2 2 2 0 Part of AAA domain Prp18 PF02840.10 EGD99903.1 - 7e-53 178.3 1.7 7.2e-53 178.3 0.0 1.9 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EGD99903.1 - 3.5e-12 45.3 2.1 3.5e-12 45.3 1.5 3.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like MAP7 PF05672.6 EGD99903.1 - 1.5 8.1 46.0 2.7 7.3 31.9 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Ycf1 PF05758.7 EGD99903.1 - 3.5 5.2 8.6 3.6 5.1 6.0 1.1 1 0 0 1 1 1 0 Ycf1 CAF-1_p150 PF11600.3 EGD99903.1 - 8 5.7 37.4 13 5.0 25.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SAP18 PF06487.7 EGD99904.1 - 1.6e-44 150.5 0.0 2.1e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) NDUF_B4 PF07225.7 EGD99905.1 - 0.0001 22.0 0.0 0.00011 21.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Nol1_Nop2_Fmu PF01189.12 EGD99906.1 - 6e-16 58.6 0.0 1.6e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family Acetyltransf_1 PF00583.19 EGD99907.1 - 2.1e-12 46.8 0.7 4.7e-12 45.7 0.5 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD99907.1 - 1.5e-10 41.1 0.0 2.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EGD99907.1 - 2.7e-08 34.3 0.0 1.7e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD99907.1 - 7.9e-06 25.9 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD99907.1 - 9.1e-06 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EGD99907.1 - 1.3e-05 25.3 0.0 1.6e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD99907.1 - 9.3e-05 22.1 0.0 0.00026 20.6 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EGD99907.1 - 0.00097 18.9 0.1 0.0022 17.8 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PmoA PF14100.1 EGD99907.1 - 0.034 13.3 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Methane oxygenase PmoA FYVE PF01363.16 EGD99908.1 - 1.7e-14 53.4 5.5 2.5e-14 52.9 3.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 EGD99908.1 - 0.042 13.7 1.6 0.092 12.6 1.1 1.5 1 0 0 1 1 1 0 IBR domain zf-AN1 PF01428.11 EGD99908.1 - 0.054 13.3 9.3 0.11 12.4 6.4 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger BTB_2 PF02214.17 EGD99909.1 - 1.4e-08 34.7 0.0 3.4e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 EGD99909.1 - 0.009 15.9 0.0 0.042 13.8 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain GST_N_3 PF13417.1 EGD99910.1 - 6.4e-10 39.1 0.1 1.5e-09 37.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD99910.1 - 8e-10 38.7 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD99910.1 - 2.9e-07 30.4 0.0 5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGD99910.1 - 0.00017 22.0 0.0 0.00028 21.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGD99910.1 - 0.00042 20.2 0.0 0.00065 19.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGD99910.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ank_4 PF13637.1 EGD99911.1 - 8.8e-06 26.0 0.0 0.00013 22.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGD99911.1 - 0.00024 21.3 0.1 0.00068 19.9 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD99911.1 - 0.0024 18.0 0.1 0.0064 16.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AMP-binding PF00501.23 EGD99913.1 - 5.6e-268 888.0 0.0 2.1e-99 332.7 0.0 4.3 3 1 1 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EGD99913.1 - 1.7e-201 667.4 3.4 1.2e-76 257.4 0.2 4.4 4 0 0 4 4 4 3 Condensation domain PP-binding PF00550.20 EGD99913.1 - 1.4e-49 166.2 0.5 2.8e-17 62.7 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site Thioesterase PF00975.15 EGD99913.1 - 1.9e-37 129.6 0.0 3.5e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.1 EGD99913.1 - 1.5e-31 109.1 0.0 4.8e-12 46.6 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EGD99913.1 - 7.6e-26 90.2 0.2 9.9e-16 57.8 0.1 4.8 4 0 0 4 4 4 3 HxxPF-repeated domain Abhydrolase_6 PF12697.2 EGD99913.1 - 1.6e-07 31.4 0.1 8e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD99913.1 - 0.00031 20.5 0.0 0.0011 18.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family 2OG-FeII_Oxy PF03171.15 EGD99914.1 - 1.2e-20 73.6 0.0 9.6e-20 70.7 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGD99914.1 - 1.4e-12 48.1 0.0 2.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_20 PF00728.17 EGD99914.1 - 0.048 12.8 0.1 0.12 11.5 0.1 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain AAT PF03417.11 EGD99915.1 - 1.5e-43 148.8 0.0 1.9e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EGD99915.1 - 0.0011 19.3 0.0 0.0028 17.9 0.0 1.7 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Peptidase_S8 PF00082.17 EGD99916.1 - 1e-48 165.9 10.3 1.5e-48 165.3 7.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD99916.1 - 4.8e-16 59.0 0.1 1.4e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I9 DUF4395 PF14340.1 EGD99917.1 - 0.062 13.3 1.0 0.13 12.2 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4395) Kdo PF06293.9 EGD99918.1 - 2.1e-07 30.2 0.1 4.5e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD99918.1 - 0.0095 15.6 0.1 0.0095 15.6 0.1 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family MAP7 PF05672.6 EGD99918.1 - 0.055 12.8 25.3 0.12 11.7 17.5 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF3043 PF11241.3 EGD99918.1 - 2 7.9 9.6 4.2 6.9 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) OmpH PF03938.9 EGD99918.1 - 4 7.3 16.3 7.8 6.4 11.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Mnd1 PF03962.10 EGD99918.1 - 6.2 6.4 11.0 20 4.7 7.7 1.8 1 0 0 1 1 1 0 Mnd1 family DUF874 PF05917.6 EGD99918.1 - 8.1 5.1 9.2 14 4.3 6.4 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Peptidase_S41 PF03572.13 EGD99919.1 - 9.6e-08 31.6 0.0 2.5e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Flg_bb_rod PF00460.15 EGD99920.1 - 0.022 14.4 0.0 0.053 13.2 0.0 1.7 1 0 0 1 1 1 0 Flagella basal body rod protein Transferase PF02458.10 EGD99921.1 - 2.1e-19 69.2 0.0 1.5e-12 46.7 0.0 3.0 3 0 0 3 3 3 3 Transferase family TAF4 PF05236.9 EGD99924.1 - 2.1e-15 56.7 7.2 4.7e-09 35.8 5.3 3.4 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family DUF1922 PF09082.5 EGD99924.1 - 0.16 12.0 0.2 0.33 11.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) CPSF73-100_C PF11718.3 EGD99925.1 - 4.4e-69 232.1 0.0 6.2e-67 225.1 0.0 2.3 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EGD99925.1 - 5.7e-33 113.5 0.0 1.3e-32 112.3 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EGD99925.1 - 6e-19 68.4 0.1 1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGD99925.1 - 7e-11 42.0 0.4 1.2e-10 41.2 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EGD99925.1 - 9.9e-07 28.4 0.2 2.2e-06 27.3 0.2 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EGD99925.1 - 0.00011 21.9 0.1 0.00054 19.7 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain FAD_binding_4 PF01565.18 EGD99926.1 - 1.4e-23 82.9 0.6 2.7e-23 81.9 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD99926.1 - 1.1e-13 50.8 0.4 2.4e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like DPBB_1 PF03330.13 EGD99927.1 - 0.00075 19.4 0.6 0.0015 18.5 0.4 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGD99927.1 - 0.003 17.2 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Barwin family Pkinase PF00069.20 EGD99928.1 - 6.2e-56 189.4 0.0 1.2e-55 188.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD99928.1 - 5.4e-20 71.5 0.0 2.2e-19 69.5 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Mtc PF03820.12 EGD99930.1 - 2.1e-104 348.5 0.1 3.7e-103 344.4 0.1 1.9 1 1 0 1 1 1 1 Tricarboxylate carrier PHD PF00628.24 EGD99931.1 - 2.5e-08 33.4 7.3 4.5e-08 32.6 5.1 1.4 1 0 0 1 1 1 1 PHD-finger DUF2293 PF10056.4 EGD99932.1 - 1.1e-24 86.2 1.0 1.5e-24 85.7 0.7 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) DUF3887 PF13026.1 EGD99932.1 - 0.094 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) RPE65 PF03055.10 EGD99933.1 - 1e-117 393.6 0.0 1.2e-117 393.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Acetyltransf_1 PF00583.19 EGD99935.1 - 7.9e-06 25.8 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD99935.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Cupin_1 PF00190.17 EGD99936.1 - 6.4e-26 90.5 0.0 3.6e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EGD99936.1 - 1.3e-19 69.4 1.6 8.7e-09 34.7 0.1 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EGD99936.1 - 7.7e-05 22.3 1.2 0.029 14.0 0.2 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 EGD99936.1 - 8.8e-05 21.8 0.2 0.14 11.5 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF861) 3-HAO PF06052.7 EGD99936.1 - 0.067 12.6 0.0 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.2 EGD99936.1 - 0.085 12.4 0.0 0.9 9.1 0.0 2.2 1 1 1 2 2 2 0 Cupin Cupin_4 PF08007.7 EGD99936.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein TruD PF01142.13 EGD99937.1 - 1.6e-53 181.7 0.0 4.9e-51 173.5 0.0 3.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) BNR PF02012.15 EGD99938.1 - 0.013 15.2 0.2 0.059 13.2 0.1 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat APH PF01636.18 EGD99939.1 - 2.3e-15 57.0 1.1 6.2e-15 55.5 0.1 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD99939.1 - 0.00013 21.6 0.0 0.00032 20.3 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase NADHdh_A3 PF14987.1 EGD99939.1 - 0.022 14.6 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 DUF3188 PF11384.3 EGD99942.1 - 1.3 8.6 6.6 2.7 7.6 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) CBS PF00571.23 EGD99943.1 - 3.9e-12 45.7 0.3 1.2e-05 24.9 0.0 2.6 3 0 0 3 3 3 2 CBS domain P5CR_dimer PF14748.1 EGD99944.1 - 3.4e-30 104.1 2.4 5.5e-30 103.5 1.7 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EGD99944.1 - 8e-10 39.0 0.1 2.6e-07 30.9 0.0 3.0 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent CTK3 PF12243.3 EGD99945.1 - 8.6e-57 190.6 0.2 1.3e-56 190.1 0.2 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EGD99945.1 - 8.8e-21 73.7 9.9 2.5e-20 72.2 6.9 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus U3_snoRNA_assoc PF08297.6 EGD99946.1 - 1.3e-08 34.9 0.2 1.3e-08 34.9 0.2 4.5 3 3 1 4 4 4 1 U3 snoRNA associated Borrelia_P83 PF05262.6 EGD99946.1 - 0.067 11.4 16.4 0.11 10.8 11.3 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein HNH_2 PF13391.1 EGD99947.1 - 2.1e-12 46.6 0.0 3.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease AbiH PF14253.1 EGD99949.1 - 0.00063 19.4 0.1 0.0012 18.4 0.1 1.5 1 0 0 1 1 1 1 Bacteriophage abortive infection AbiH DUF155 PF02582.9 EGD99950.1 - 7.9e-52 175.6 0.2 1.2e-51 175.1 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Trypsin_2 PF13365.1 EGD99952.1 - 1.1e-05 25.3 0.0 4e-05 23.6 0.0 1.9 1 1 1 2 2 2 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.6 EGD99952.1 - 0.00053 18.4 0.0 0.052 11.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S32 PF05579.8 EGD99952.1 - 0.034 13.1 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 DUF955 PF06114.8 EGD99952.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF955) Peptidase_S46 PF10459.4 EGD99952.1 - 0.19 10.0 0.0 0.29 9.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase S46 PufQ PF05398.6 EGD99953.1 - 5.9 7.0 7.4 2.5 8.2 0.2 2.6 1 1 1 2 2 2 0 PufQ cytochrome subunit p450 PF00067.17 EGD99954.1 - 2.4e-68 230.7 0.0 2.8e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGD99955.1 - 5.1e-57 193.4 0.0 6.6e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 EGD99956.1 - 0.004 16.4 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain adh_short PF00106.20 EGD99957.1 - 2.4e-17 63.3 0.0 4.9e-17 62.3 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGD99957.1 - 7.3e-06 25.7 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD99957.1 - 3.8e-05 23.5 0.0 6.9e-05 22.7 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EGD99957.1 - 0.00053 20.0 0.1 0.00096 19.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EGD99957.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 2 0 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 EGD99957.1 - 0.033 13.6 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EGD99957.1 - 0.059 13.7 0.2 0.16 12.3 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RVT_1 PF00078.22 EGD99960.1 - 6.1e-26 91.0 0.0 1.3e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EGD99960.1 - 1.1e-20 73.4 0.0 3.7e-20 71.7 0.0 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EGD99960.1 - 1.1e-09 38.7 1.0 6.9e-08 32.9 0.1 3.4 2 1 0 2 2 2 1 RNase H Exo_endo_phos PF03372.18 EGD99960.1 - 1.3e-05 25.3 0.2 2.7e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HALZ PF02183.13 EGD99960.1 - 0.0033 17.1 1.8 0.0033 17.1 1.2 1.9 2 0 0 2 2 2 1 Homeobox associated leucine zipper zf-CCHC_3 PF13917.1 EGD99960.1 - 0.0059 16.3 0.6 0.018 14.8 0.4 1.8 1 0 0 1 1 1 1 Zinc knuckle DivIC PF04977.10 EGD99960.1 - 0.014 14.8 0.8 0.049 13.1 0.6 2.0 1 0 0 1 1 1 0 Septum formation initiator DUF1664 PF07889.7 EGD99960.1 - 0.24 11.1 3.2 0.2 11.4 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 EGD99960.1 - 0.28 11.5 1.5 1.3 9.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Pkinase PF00069.20 EGD99961.1 - 0.00019 20.6 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain zf-C2H2 PF00096.21 EGD99962.1 - 0.003 17.8 0.1 0.0066 16.7 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD99962.1 - 0.037 14.3 0.1 0.094 13.0 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGD99962.1 - 0.056 13.5 0.7 0.088 12.9 0.5 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) NB-ARC PF00931.17 EGD99965.1 - 2e-07 30.1 0.0 5.7e-07 28.6 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_17 PF13207.1 EGD99965.1 - 0.018 15.8 0.0 0.047 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGD99965.1 - 0.025 14.7 0.0 0.11 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGD99965.1 - 0.041 13.6 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 NTPase TPR_10 PF13374.1 EGD99965.1 - 0.041 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat WH1 PF00568.18 EGD99965.1 - 0.092 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 WH1 domain CtIP_N PF10482.4 EGD99974.1 - 0.00022 20.9 1.1 0.0004 20.1 0.8 1.3 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain CENP-Q PF13094.1 EGD99974.1 - 0.081 12.9 3.1 0.15 12.0 2.1 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Hat1_N PF10394.4 EGD99975.1 - 8.3e-48 162.4 0.1 1.7e-47 161.4 0.1 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus ENT PF03735.9 EGD99975.1 - 0.058 13.1 0.3 4.1 7.2 0.1 2.9 3 0 0 3 3 3 0 ENT domain DUF917 PF06032.7 EGD99976.1 - 3.6e-103 344.8 3.6 1.8e-102 342.5 0.0 3.1 3 1 1 4 4 4 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EGD99976.1 - 1.7e-51 175.0 11.6 1.8e-50 171.6 4.2 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGD99976.1 - 2.8e-31 108.3 7.4 2.3e-27 95.6 0.0 4.5 4 0 0 4 4 4 3 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 EGD99976.1 - 0.0037 16.6 0.4 0.0037 16.6 0.3 2.7 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 EGD99976.1 - 0.047 12.6 0.2 1.8 7.4 0.0 2.5 2 0 0 2 2 2 0 StbA protein Transp_cyt_pur PF02133.10 EGD99977.1 - 2.7e-94 316.2 39.1 2.5e-93 313.0 27.1 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Zip PF02535.17 EGD99978.1 - 1.1e-36 126.4 28.3 2.6e-28 98.9 11.4 3.5 1 1 1 2 2 2 2 ZIP Zinc transporter DUF4131 PF13567.1 EGD99978.1 - 0.11 11.9 1.6 2.6 7.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) SelP_N PF04592.9 EGD99978.1 - 8.5 5.6 6.8 14 4.9 4.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region WD40 PF00400.27 EGD99979.1 - 8.4e-52 171.3 19.2 4.4e-09 35.8 0.2 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 EGD99979.1 - 1.7e-10 40.4 0.6 3.1e-10 39.6 0.4 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EGD99979.1 - 1.1e-09 37.0 6.6 0.0033 15.6 0.1 4.9 1 1 5 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGD99979.1 - 0.00032 19.5 2.3 0.0022 16.8 0.6 3.0 1 1 0 2 2 2 1 Nup133 N terminal like F-box PF00646.28 EGD99979.1 - 0.00071 19.1 0.6 0.0017 17.9 0.4 1.7 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 EGD99979.1 - 0.019 15.2 0.4 44 4.5 0.0 4.6 4 1 1 5 5 5 0 PQQ-like domain PQQ_2 PF13360.1 EGD99979.1 - 0.036 13.5 2.7 0.71 9.2 0.2 3.0 1 1 1 3 3 3 0 PQQ-like domain PyrBI_leader PF08052.6 EGD99979.1 - 0.098 12.4 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 PyrBI operon leader peptide Raptor_N PF14538.1 EGD99981.1 - 0.027 14.3 0.0 8.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Sugar_tr PF00083.19 EGD99982.1 - 1.3e-84 284.4 26.9 2.1e-84 283.6 18.0 1.5 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD99982.1 - 2.5e-11 42.9 46.6 2.4e-07 29.8 11.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EGD99983.1 - 2.1e-13 49.7 0.8 2.1e-13 49.7 0.5 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD99983.1 - 0.0011 18.8 12.7 0.0023 17.8 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EGD99983.1 - 2.8 8.1 10.4 7.7 6.7 7.2 1.7 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region RINGv PF12906.2 EGD99985.1 - 1.6e-09 37.6 2.6 1e-08 35.1 0.5 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EGD99985.1 - 0.0042 16.8 3.2 0.022 14.5 0.5 2.2 2 0 0 2 2 2 1 Ring finger domain DUF1674 PF07896.7 EGD99985.1 - 0.14 12.3 2.4 0.31 11.2 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) PHD PF00628.24 EGD99985.1 - 1.1 9.0 5.7 0.34 10.6 1.7 1.8 2 0 0 2 2 2 0 PHD-finger Proteasome PF00227.21 EGD99986.1 - 1.8e-57 193.7 0.0 7e-33 113.5 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EGD99986.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltransf_2 PF00891.13 EGD99986.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Ribonuclease_3 PF00636.21 EGD99987.1 - 1.2e-43 148.2 0.0 7.1e-21 74.7 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGD99987.1 - 2.7e-21 75.8 0.2 1.5e-12 47.6 0.0 3.7 2 1 0 2 2 2 2 Ribonuclease-III-like DEAD PF00270.24 EGD99987.1 - 1.7e-20 73.1 0.0 3.7e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.9 EGD99987.1 - 6.3e-20 70.7 0.0 1.2e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 EGD99987.1 - 3.8e-14 52.2 0.0 1.6e-13 50.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD99987.1 - 1.4e-10 41.2 0.0 2.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 EGD99987.1 - 0.0096 16.4 0.4 0.055 14.0 0.0 2.3 2 0 0 2 2 2 1 Double-stranded RNA binding motif zf-C2H2_jaz PF12171.3 EGD99991.1 - 0.012 15.7 0.4 0.14 12.3 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.9 EGD99991.1 - 0.08 12.5 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2 PF00096.21 EGD99991.1 - 0.2 12.0 2.7 2.2 8.7 0.0 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-LYAR PF08790.6 EGD99991.1 - 1.2 8.9 3.4 4.4 7.0 0.1 2.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.1 EGD99991.1 - 3.5 8.1 6.6 2 8.8 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double domain 6PGD PF00393.14 EGD99992.1 - 5.3e-53 180.1 0.0 9.8e-53 179.2 0.0 1.4 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGD99992.1 - 1e-31 110.0 0.2 1.8e-31 109.2 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EGD99992.1 - 4.7e-07 29.6 0.1 8.7e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EGD99992.1 - 7.9e-06 25.6 0.1 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EGD99992.1 - 0.0021 18.1 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EGD99992.1 - 0.0026 18.1 0.0 0.0073 16.7 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EGD99992.1 - 0.0042 16.4 0.2 0.011 15.1 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EGD99992.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EGD99992.1 - 0.044 12.9 1.4 0.044 12.9 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EGD99992.1 - 0.056 13.4 0.1 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD99992.1 - 0.06 12.2 0.1 0.1 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase RTA1 PF04479.8 EGD99993.1 - 4.5e-45 153.8 1.7 6.1e-45 153.4 1.2 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF805 PF05656.9 EGD99993.1 - 2.4 7.9 13.9 0.35 10.7 0.3 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF805) Zn_clus PF00172.13 EGD99994.1 - 2.1e-08 33.9 10.6 3.4e-08 33.2 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGD99994.1 - 0.00041 19.0 0.0 0.00065 18.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EB PF01683.13 EGD99995.1 - 0.0012 18.8 6.1 0.0014 18.6 4.2 1.1 1 0 0 1 1 1 1 EB module LSM PF01423.17 EGD99996.1 - 1.1e-12 47.3 1.1 1.2e-12 47.1 0.1 1.6 2 0 0 2 2 2 1 LSM domain NUC173 PF08161.7 EGD99997.1 - 8.4e-76 253.7 0.1 8.1e-74 247.2 0.0 2.7 2 0 0 2 2 2 2 NUC173 domain PsiA PF06952.6 EGD99997.1 - 0.19 10.7 2.7 0.5 9.3 1.9 1.7 1 0 0 1 1 1 0 PsiA protein RasGAP PF00616.14 EGD99997.1 - 0.36 10.4 3.5 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase SpoVR PF04293.8 EGD99997.1 - 2.9 6.1 5.6 6.6 4.9 0.1 2.2 2 0 0 2 2 2 0 SpoVR like protein CENP-B_dimeris PF09026.5 EGD99998.1 - 0.0011 19.1 19.3 0.0024 18.0 5.3 2.5 2 0 0 2 2 2 2 Centromere protein B dimerisation domain PBP1_TM PF14812.1 EGD99998.1 - 0.0025 18.0 11.6 0.0025 18.0 8.0 3.5 4 0 0 4 4 4 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Radial_spoke PF04712.7 EGD99998.1 - 1.6 7.3 5.7 2.5 6.7 4.0 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein NPR3 PF03666.8 EGD99998.1 - 2.4 6.5 7.3 0.49 8.8 0.6 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2615 PF11027.3 EGD99999.1 - 0.00047 20.0 0.8 0.00079 19.3 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) NST1 PF13945.1 EGD99999.1 - 0.0033 17.5 3.7 0.0041 17.2 2.6 1.1 1 0 0 1 1 1 1 Salt tolerance down-regulator DUF3357 PF11837.3 EGD99999.1 - 0.0078 16.0 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) NfeD PF01957.13 EGD99999.1 - 0.011 15.9 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding FAM176 PF14851.1 EGD99999.1 - 0.017 14.8 0.5 0.021 14.5 0.4 1.1 1 0 0 1 1 1 0 FAM176 family OSTbeta PF15048.1 EGD99999.1 - 0.025 14.6 1.2 0.033 14.2 0.8 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Conotoxin PF02950.12 EGD99999.1 - 0.029 15.1 1.7 0.034 14.9 0.7 1.5 1 1 1 2 2 2 0 Conotoxin PIG-P PF08510.7 EGD99999.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 PIG-P DUF1754 PF08555.5 EGD99999.1 - 0.29 11.7 9.8 0.37 11.4 6.8 1.1 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Bap31 PF05529.7 EGD99999.1 - 0.34 10.3 4.2 0.43 10.0 2.9 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Atg14 PF10186.4 EGD99999.1 - 0.52 9.2 3.7 0.56 9.1 2.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 STAG PF08514.6 EGD99999.1 - 0.54 9.9 5.0 0.12 12.0 1.3 1.5 2 0 0 2 2 2 0 STAG domain GRP PF07172.6 EGD99999.1 - 2.5 8.6 5.0 0.34 11.3 0.3 2.0 2 1 0 2 2 2 0 Glycine rich protein family TPR_1 PF00515.23 EGE00001.1 - 1e-49 164.1 31.3 5.8e-08 32.0 0.0 11.3 10 2 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 EGE00001.1 - 4.5e-45 147.9 22.6 9.2e-06 25.2 0.0 11.3 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EGE00001.1 - 2.2e-42 142.5 24.0 1.5e-10 40.5 0.4 6.6 2 2 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 EGE00001.1 - 8.1e-36 119.1 21.7 3.7e-05 23.1 0.6 10.2 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 EGE00001.1 - 2.3e-27 95.0 31.0 3.6e-06 27.5 0.0 7.2 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGE00001.1 - 5.4e-24 83.9 37.6 5.3e-08 32.6 0.7 8.0 3 2 6 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EGE00001.1 - 1.9e-21 74.4 31.3 0.00029 20.8 0.1 10.4 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGE00001.1 - 1.1e-19 69.0 35.6 0.00016 22.0 0.1 11.4 4 2 8 12 12 10 7 Tetratricopeptide repeat TPR_7 PF13176.1 EGE00001.1 - 1.5e-18 65.0 18.0 0.011 15.5 0.1 9.5 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 EGE00001.1 - 1.5e-17 62.7 33.9 0.0022 18.3 0.0 11.3 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGE00001.1 - 1.7e-14 53.8 42.0 2.1e-06 27.9 0.3 7.6 6 2 3 9 9 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EGE00001.1 - 7.2e-14 51.6 10.1 4.6e-08 33.0 2.2 4.1 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGE00001.1 - 1.8e-08 34.1 33.3 0.00017 21.3 0.2 7.4 4 2 4 8 8 7 4 Tetratricopeptide repeat TPR_15 PF13429.1 EGE00001.1 - 2.6e-05 23.4 25.4 0.0025 16.9 1.7 5.6 2 1 2 5 5 5 3 Tetratricopeptide repeat DUF2225 PF09986.4 EGE00001.1 - 0.0021 17.5 5.8 0.66 9.4 0.0 3.0 3 1 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) CAF-1_p150 PF11600.3 EGE00001.1 - 0.0023 17.3 41.5 0.0023 17.3 28.8 4.5 5 0 0 5 5 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal ChAPs PF09295.5 EGE00001.1 - 0.71 8.5 2.8 3.1 6.4 0.2 2.6 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 EGE00001.1 - 1.8 8.4 33.0 0.26 11.1 2.8 4.8 3 1 1 4 4 3 0 Tetratricopeptide repeat Ribosomal_L3 PF00297.17 EGE00003.1 - 3.4e-117 390.5 6.7 4.1e-117 390.2 4.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3123 PF11321.3 EGE00004.1 - 0.086 13.1 0.3 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) NuiA PF07924.6 EGE00004.1 - 0.11 12.4 0.1 0.59 10.0 0.1 2.1 1 1 0 1 1 1 0 Nuclease A inhibitor-like protein SR-25 PF10500.4 EGE00004.1 - 0.81 9.1 10.3 0.26 10.7 5.0 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 EGE00004.1 - 8.4 6.4 11.5 1.4 8.9 5.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SKN1 PF03935.10 EGE00005.1 - 1.4e-222 739.2 0.1 1.7e-222 739.0 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Trp_DMAT PF11991.3 EGE00006.1 - 3.5e-124 414.6 0.0 4.3e-124 414.3 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase FAD_binding_4 PF01565.18 EGE00007.1 - 7.2e-22 77.3 0.8 1.8e-21 76.0 0.5 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGE00007.1 - 9.2e-09 35.0 0.3 2.1e-08 33.9 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_33 PF10017.4 EGE00008.1 - 2.2e-28 98.6 0.0 7.1e-28 97.0 0.0 1.8 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 EGE00008.1 - 0.0077 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EGE00009.1 - 2.2e-22 79.7 0.0 3.9e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE00009.1 - 1.6e-18 67.4 0.0 2.1e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE00009.1 - 7.1e-12 45.3 0.1 1.3e-11 44.4 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGE00009.1 - 8e-05 22.1 0.0 0.0013 18.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGE00009.1 - 0.00046 19.1 0.0 0.00068 18.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF4332 PF14229.1 EGE00009.1 - 0.0068 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) NAD_binding_10 PF13460.1 EGE00009.1 - 0.011 15.7 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding Catalase PF00199.14 EGE00010.1 - 9.7e-115 383.2 0.5 1.6e-96 323.3 0.4 2.0 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.7 EGE00010.1 - 1.6e-07 31.1 0.0 5.3e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Lumazine_bd_2 PF12893.2 EGE00011.1 - 5.8e-25 88.0 0.0 6.8e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Putative lumazine-binding Lumazine_bd PF12870.2 EGE00011.1 - 0.00019 21.4 0.0 0.001 19.0 0.0 2.0 1 1 0 1 1 1 1 Lumazine-binding domain NmrA PF05368.8 EGE00012.1 - 5.4e-14 52.0 0.0 6.8e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGE00012.1 - 1.4e-06 28.4 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGE00012.1 - 6.5e-06 25.7 0.0 0.01 15.2 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EGE00012.1 - 7e-05 22.8 0.1 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EGE00012.1 - 0.0018 17.3 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase CoA_binding_3 PF13727.1 EGE00012.1 - 0.0037 17.1 0.1 0.0051 16.6 0.1 1.2 1 0 0 1 1 1 1 CoA-binding domain Ribonuc_L-PSP PF01042.16 EGE00013.1 - 9.4e-41 138.3 0.0 1e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Membr_traf_MHD PF10540.4 EGE00014.1 - 5.3e-26 91.0 0.0 1.6e-25 89.4 0.0 1.9 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EGE00014.1 - 1.1e-13 50.8 0.0 2.4e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 EGE00014.1 - 3.9e-06 25.4 0.1 6.3e-06 24.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF810) NDUF_B8 PF05821.6 EGE00015.1 - 6.9e-05 22.5 0.0 7.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 EGE00016.1 - 3.6e-73 245.9 0.9 5.6e-73 245.3 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE00016.1 - 4.4e-15 55.3 0.0 1.2e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE00016.1 - 3.8e-07 30.1 0.2 1.3e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGE00016.1 - 1e-05 25.1 0.1 8.9e-05 22.0 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase HSA PF07529.8 EGE00016.1 - 4.8e-05 23.0 6.4 0.00019 21.1 4.4 2.0 1 0 0 1 1 1 1 HSA Clr5 PF14420.1 EGE00017.1 - 5e-14 51.9 1.1 8.7e-14 51.1 0.8 1.4 1 0 0 1 1 1 1 Clr5 domain ADH_zinc_N PF00107.21 EGE00018.1 - 7.6e-30 103.1 0.5 1.2e-29 102.4 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGE00018.1 - 7.1e-10 39.8 0.1 1.9e-09 38.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGE00018.1 - 1.4e-07 31.2 0.0 5.3e-07 29.3 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pep_deformylase PF01327.16 EGE00018.1 - 0.12 11.7 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Polypeptide deformylase GRP PF07172.6 EGE00019.1 - 7.7 7.0 36.3 1.9e+02 2.5 25.2 2.2 1 1 0 1 1 1 0 Glycine rich protein family zf-Mss51 PF13824.1 EGE00020.1 - 1.9e-28 98.0 8.7 5.7e-28 96.5 6.1 1.9 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EGE00020.1 - 0.0044 16.8 2.7 0.0044 16.8 1.9 2.0 2 0 0 2 2 2 1 MYND finger GFA PF04828.9 EGE00020.1 - 0.091 12.7 0.7 0.27 11.2 0.1 2.0 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Oxysterol_BP PF01237.13 EGE00021.1 - 5.7e-133 442.7 0.0 1.4e-132 441.4 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 EGE00021.1 - 6e-22 77.7 0.2 1.5e-10 41.2 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGE00021.1 - 8.2e-18 64.0 0.3 1.2e-11 44.4 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EGE00021.1 - 6.8e-15 54.0 0.2 3.2e-06 26.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EGE00021.1 - 2.3e-12 45.8 0.0 3.4e-05 23.6 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EGE00021.1 - 7.1e-10 39.1 0.1 1.3e-05 25.5 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) LLC1 PF14945.1 EGE00021.1 - 0.012 15.9 1.2 0.012 15.9 0.8 3.1 3 0 0 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein ATP12 PF07542.6 EGE00022.1 - 4.3e-34 117.0 0.1 6.4e-34 116.5 0.1 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein RNase_H2-Ydr279 PF09468.5 EGE00025.1 - 0.18 10.9 4.5 0.18 10.9 3.1 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Med19 PF10278.4 EGE00025.1 - 0.48 10.0 11.8 0.57 9.8 8.2 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 NARP1 PF12569.3 EGE00025.1 - 0.59 8.8 5.1 0.55 8.9 3.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FLO_LFY PF01698.11 EGE00025.1 - 0.83 8.4 5.9 0.84 8.4 4.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein YqfQ PF14181.1 EGE00025.1 - 0.85 9.6 4.7 0.99 9.4 3.3 1.1 1 0 0 1 1 1 0 YqfQ-like protein BRF1 PF07741.8 EGE00025.1 - 3.6 7.8 10.5 4.8 7.4 7.2 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Peptidase_S49_N PF08496.5 EGE00025.1 - 8.1 6.2 7.1 8.8 6.1 4.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Glyco_tranf_2_3 PF13641.1 EGE00026.1 - 4e-25 88.9 0.1 6.1e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGE00026.1 - 1.6e-07 30.7 0.0 0.00025 20.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGE00026.1 - 4.3e-07 29.7 0.0 7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EGE00026.1 - 0.0068 16.1 14.8 0.12 12.0 10.3 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 SH3_1 PF00018.23 EGE00028.1 - 1.8e-14 52.8 0.0 2.8e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGE00028.1 - 9.8e-13 47.4 0.0 3.1e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EGE00028.1 - 5.2e-09 35.4 0.0 8.9e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.11 EGE00029.1 - 5.9e-15 54.8 63.9 1e-13 50.7 36.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Brr6_like_C_C PF10104.4 EGE00029.1 - 0.053 13.0 0.1 0.28 10.7 0.0 2.3 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain MBF1 PF08523.5 EGE00030.1 - 2.4e-27 94.7 0.4 4.6e-27 93.8 0.3 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EGE00030.1 - 1.2e-11 44.3 0.1 2.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EGE00030.1 - 1e-07 32.0 0.3 2.4e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 EGE00030.1 - 0.00056 19.9 0.0 0.00078 19.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Iso_dh PF00180.15 EGE00031.1 - 1.8e-69 234.3 0.0 2.2e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FTHFS PF01268.14 EGE00033.1 - 4e-256 850.3 0.0 5.9e-256 849.8 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EGE00033.1 - 4.9e-67 224.0 0.6 4.9e-67 224.0 0.4 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EGE00033.1 - 1.5e-35 121.7 0.2 3.8e-35 120.4 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain WD40 PF00400.27 EGE00034.1 - 2.6e-27 93.6 3.1 7.5e-08 31.9 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Gmad1 PF10647.4 EGE00034.1 - 0.00078 18.9 0.0 0.0028 17.1 0.0 1.7 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EGE00034.1 - 0.016 13.3 0.6 0.14 10.2 0.1 2.2 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Pkinase PF00069.20 EGE00036.1 - 1.6e-12 47.1 0.0 2.3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE00036.1 - 1.6e-06 27.3 0.0 1.5e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGE00036.1 - 0.027 14.2 0.2 0.46 10.1 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EGE00036.1 - 0.14 11.2 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RrnaAD PF00398.15 EGE00038.1 - 0.0079 15.2 0.0 0.026 13.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase DUF1524 PF07510.6 EGE00039.1 - 2.1e-08 34.1 0.0 2.7e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 EGE00039.1 - 0.0064 16.0 0.5 0.017 14.7 0.3 1.7 1 1 0 1 1 1 1 HNH endonuclease DEAD PF00270.24 EGE00041.1 - 2.5e-17 62.8 0.3 1.1e-16 60.7 0.1 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE00041.1 - 3.5e-09 36.4 0.0 7.9e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE00041.1 - 1e-06 28.7 0.0 2.6e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 EGE00041.1 - 7.6e-05 22.8 0.1 0.00027 21.0 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF4332 PF14229.1 EGE00041.1 - 0.058 13.3 0.1 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Vps53_N PF04100.7 EGE00042.1 - 2.9e-105 352.1 10.3 6.7e-105 351.0 7.2 1.6 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EGE00042.1 - 1.4e-07 30.7 8.8 2.8e-07 29.7 6.1 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EGE00042.1 - 0.0057 16.5 3.7 0.012 15.4 1.7 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 EGE00042.1 - 0.049 12.2 9.3 0.065 11.8 5.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Sporozoite_P67 PF05642.6 EGE00042.1 - 0.26 9.0 4.9 0.4 8.4 3.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen COG5 PF10392.4 EGE00042.1 - 0.27 11.2 7.4 0.35 10.8 2.3 3.2 3 0 0 3 3 3 0 Golgi transport complex subunit 5 TAP_C PF03943.8 EGE00043.1 - 3.2e-11 42.4 0.2 6.3e-11 41.5 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EGE00043.1 - 6.1e-08 32.1 5.8 7e-05 22.3 0.4 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 EGE00043.1 - 0.00075 19.8 0.0 0.0024 18.2 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.1 EGE00043.1 - 0.0043 16.6 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 EGE00043.1 - 0.0054 16.5 1.0 0.63 10.2 0.1 3.6 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_8 PF13855.1 EGE00043.1 - 0.014 15.1 0.1 0.034 13.9 0.1 1.7 1 0 0 1 1 1 0 Leucine rich repeat COPIIcoated_ERV PF07970.7 EGE00044.1 - 8.8e-68 228.2 0.0 6.5e-46 156.7 0.0 2.5 2 1 1 3 3 3 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGE00044.1 - 1.7e-34 117.6 0.0 4e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PH PF00169.24 EGE00045.1 - 0.00045 20.3 0.1 0.0032 17.6 0.0 2.4 2 1 0 2 2 2 1 PH domain zf-C2H2_4 PF13894.1 EGE00046.1 - 3.6e-26 89.5 44.9 0.0026 17.9 0.1 10.8 10 1 1 11 11 11 9 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE00046.1 - 2.4e-24 84.1 57.5 0.0021 18.2 0.5 11.4 11 1 1 12 12 12 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE00046.1 - 1e-15 57.0 49.2 0.00084 19.5 0.2 11.0 11 0 0 11 11 11 7 Zinc-finger double domain GAGA PF09237.6 EGE00046.1 - 0.00024 20.6 0.5 0.00024 20.6 0.4 2.2 2 0 0 2 2 2 1 GAGA factor zf-met PF12874.2 EGE00046.1 - 0.073 13.2 13.4 33 4.8 0.0 7.3 7 0 0 7 7 7 0 Zinc-finger of C2H2 type CHORD PF04968.7 EGE00046.1 - 0.095 12.9 14.5 2.4 8.4 0.5 4.8 3 1 1 4 4 4 0 CHORD zf-C2H2_jaz PF12171.3 EGE00046.1 - 0.18 12.0 21.2 6.5 7.0 0.0 8.0 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGE00046.1 - 3.2 7.7 13.4 39 4.3 0.2 6.4 6 0 0 6 6 6 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 EGE00046.1 - 5 7.0 11.3 0.53 10.1 1.1 3.9 3 0 0 3 3 3 0 Transposase zinc-ribbon domain RNA_pol_Rpb6 PF01192.17 EGE00047.1 - 5.1e-24 83.7 0.2 8e-24 83.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 MFS_1 PF07690.11 EGE00049.1 - 1.2e-22 80.1 52.9 5.6e-18 64.7 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APOC4 PF15119.1 EGE00049.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein C4 Acetyltransf_1 PF00583.19 EGE00050.1 - 4.6e-14 52.1 0.1 7e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGE00050.1 - 1.9e-06 27.5 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGE00050.1 - 2.8e-06 27.4 0.0 3.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGE00050.1 - 4e-05 23.7 0.0 6.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGE00050.1 - 0.00035 20.4 0.1 0.00055 19.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGE00050.1 - 0.00059 19.7 0.1 0.00075 19.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CENP-Q PF13094.1 EGE00051.1 - 1.5 8.8 11.0 1.1 9.2 4.8 2.4 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PCI PF01399.22 EGE00052.1 - 3.3e-12 46.6 0.6 1.4e-10 41.4 0.0 3.1 2 0 0 2 2 2 1 PCI domain BAH PF01426.13 EGE00052.1 - 0.021 14.5 1.5 0.053 13.2 1.0 1.7 1 0 0 1 1 1 0 BAH domain RNA_polI_A34 PF08208.6 EGE00053.1 - 0.002 17.8 2.7 0.0021 17.7 1.9 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Daxx PF03344.10 EGE00053.1 - 0.26 9.7 8.6 0.22 9.9 6.0 1.0 1 0 0 1 1 1 0 Daxx Family Paf1 PF03985.8 EGE00053.1 - 0.3 9.7 10.4 0.33 9.6 7.2 1.0 1 0 0 1 1 1 0 Paf1 BUD22 PF09073.5 EGE00053.1 - 0.31 10.0 14.3 0.32 10.0 9.9 1.0 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 EGE00053.1 - 0.51 9.8 6.6 0.64 9.5 4.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1510 PF07423.6 EGE00053.1 - 0.69 9.2 9.7 0.88 8.8 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 EGE00053.1 - 1.1 8.8 6.8 1.5 8.4 4.7 1.1 1 0 0 1 1 1 0 FAM176 family Myc_N PF01056.13 EGE00053.1 - 1.2 8.2 7.1 1.3 8.0 4.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region VID27 PF08553.5 EGE00053.1 - 1.4 7.0 10.1 1.6 6.8 7.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DDHD PF02862.12 EGE00053.1 - 1.6 8.4 4.8 1.8 8.3 3.3 1.0 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 EGE00053.1 - 2.3 6.1 8.8 2.7 5.9 6.1 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.9 EGE00053.1 - 2.9 7.8 6.7 3.8 7.5 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sec62 PF03839.11 EGE00053.1 - 3.6 6.9 5.4 4.7 6.5 3.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 TRAP_alpha PF03896.11 EGE00053.1 - 5.1 5.9 6.1 6.4 5.6 4.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Prog_receptor PF02161.10 EGE00053.1 - 5.7 5.6 7.6 6.5 5.4 5.3 1.0 1 0 0 1 1 1 0 Progesterone receptor Radial_spoke PF04712.7 EGE00053.1 - 6.6 5.3 12.5 8 5.0 8.7 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein DDRGK PF09756.4 EGE00053.1 - 7.1 5.9 17.6 8.8 5.6 12.2 1.1 1 0 0 1 1 1 0 DDRGK domain YqfQ PF14181.1 EGE00053.1 - 8.3 6.4 9.5 11 6.0 6.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein Ycf1 PF05758.7 EGE00053.1 - 9.4 3.8 6.6 10 3.6 4.6 1.0 1 0 0 1 1 1 0 Ycf1 G-gamma PF00631.17 EGE00054.1 - 1.9e-21 75.5 0.0 2.2e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 GGL domain Metal_resist PF13801.1 EGE00055.1 - 0.045 13.7 3.5 0.13 12.2 2.4 1.8 1 0 0 1 1 1 0 Heavy-metal resistance Phostensin_N PF13916.1 EGE00055.1 - 0.36 10.8 4.1 1.2 9.2 2.9 1.9 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Ofd1_CTDD PF10637.4 EGE00057.1 - 1.1e-95 319.7 0.1 1.7e-90 302.8 0.3 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EGE00057.1 - 2.7e-15 56.6 0.0 5.1e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGE00057.1 - 0.0069 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.18 EGE00058.1 - 2.8e-07 30.5 0.0 1.4e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family COesterase PF00135.23 EGE00060.1 - 7.7e-97 325.2 0.0 1.1e-96 324.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGE00060.1 - 2.5e-07 30.4 0.2 2.4e-06 27.2 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGE00060.1 - 0.077 12.2 0.2 0.13 11.4 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family p450 PF00067.17 EGE00062.1 - 6.7e-67 225.9 0.0 9.1e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.17 EGE00062.1 - 0.048 13.4 0.6 0.089 12.6 0.4 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit FAD_binding_4 PF01565.18 EGE00063.1 - 2.5e-34 117.7 6.6 1.1e-33 115.6 4.3 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EGE00063.1 - 0.0025 17.6 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EGE00064.1 - 1.3e-19 70.0 0.8 2.3e-19 69.2 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain DRMBL PF07522.9 EGE00065.1 - 1.1e-32 112.3 0.0 2.2e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EGE00065.1 - 1.6e-10 40.8 0.1 4.9e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGE00065.1 - 0.078 12.6 1.5 0.2 11.2 1.0 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily LSM PF01423.17 EGE00066.1 - 3.2e-15 55.4 1.0 4.4e-15 54.9 0.7 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 EGE00066.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.1 EGE00066.1 - 0.095 12.6 0.1 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Methyltransf_11 PF08241.7 EGE00067.1 - 1.3e-06 28.7 0.0 2.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE00067.1 - 0.0052 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain zf-BED PF02892.10 EGE00068.1 - 0.0048 16.6 4.7 0.39 10.5 0.6 2.5 2 0 0 2 2 2 2 BED zinc finger SH3BGR PF04908.10 EGE00070.1 - 0.00062 19.6 0.0 0.0027 17.6 0.0 2.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EGE00070.1 - 0.096 12.6 0.1 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin Pkinase PF00069.20 EGE00071.1 - 8.9e-22 77.4 0.0 4.9e-21 75.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE00071.1 - 4.7e-08 32.4 0.0 6.5e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE00071.1 - 0.0066 16.2 0.8 0.032 13.9 0.3 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE00071.1 - 0.066 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGE00071.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ribul_P_3_epim PF00834.14 EGE00072.1 - 6.6e-63 211.4 0.0 1e-61 207.5 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Melibiase PF02065.13 EGE00072.1 - 0.039 12.6 0.1 0.47 9.0 0.0 2.0 2 0 0 2 2 2 0 Melibiase OMPdecase PF00215.19 EGE00072.1 - 0.074 12.4 0.6 0.18 11.2 0.3 1.4 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 EGE00072.1 - 0.074 12.1 0.5 0.1 11.6 0.3 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG zf-C2H2_4 PF13894.1 EGE00073.1 - 0.046 14.0 0.4 0.046 14.0 0.3 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE00073.1 - 5.5 7.5 15.2 5.5 7.5 0.2 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF3834 PF12916.2 EGE00075.1 - 0.074 12.0 0.0 0.099 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) ABC2_membrane PF01061.19 EGE00076.1 - 7.3e-91 303.0 60.6 1.4e-48 164.8 13.8 3.0 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EGE00076.1 - 3.1e-38 129.5 3.7 5.5e-34 115.9 0.0 3.2 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EGE00076.1 - 1.7e-36 125.5 0.0 6.4e-17 62.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 EGE00076.1 - 2.4e-24 85.2 0.0 5.4e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EGE00076.1 - 3.5e-08 32.8 52.9 0.00016 20.8 13.7 3.4 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 EGE00076.1 - 1.7e-06 27.5 0.0 0.00018 20.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGE00076.1 - 6.4e-06 25.4 0.1 0.0016 17.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EGE00076.1 - 1e-05 25.4 0.0 0.00039 20.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGE00076.1 - 0.00017 21.9 0.1 0.046 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EGE00076.1 - 0.00028 20.3 0.7 0.012 15.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EGE00076.1 - 0.0003 20.2 0.7 0.035 13.6 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EGE00076.1 - 0.0021 18.0 1.9 0.2 11.6 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EGE00076.1 - 0.0035 17.4 0.1 0.9 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGE00076.1 - 0.0043 17.8 0.0 0.36 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGE00076.1 - 0.035 14.0 0.1 0.71 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EGE00076.1 - 0.041 13.1 0.0 2.6 7.2 0.0 3.0 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 EGE00076.1 - 0.064 13.0 1.0 3 7.6 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EGE00076.1 - 0.065 12.8 2.1 2.1 7.9 0.1 2.8 3 0 0 3 3 3 0 NACHT domain AAA_21 PF13304.1 EGE00076.1 - 0.068 13.1 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EGE00076.1 - 0.075 12.9 0.1 9.7 6.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 EGE00076.1 - 0.099 12.1 0.0 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EGE00076.1 - 0.16 11.4 0.1 5.2 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain MS_channel PF00924.13 EGE00078.1 - 1.9e-24 86.1 2.4 4.5e-24 84.9 1.6 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EGE00078.1 - 3.8e-05 22.6 0.4 8.9e-05 21.5 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EGE00078.1 - 0.00012 21.2 0.2 0.00031 19.9 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EGE00078.1 - 0.00041 20.4 0.6 0.001 19.1 0.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EGE00078.1 - 0.00049 19.7 0.1 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain DUF2648 PF10855.3 EGE00078.1 - 0.035 13.5 0.0 0.093 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Tubulin PF00091.20 EGE00080.1 - 3.1e-64 216.7 0.0 4.2e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGE00080.1 - 4.3e-43 146.3 0.0 6.6e-43 145.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGE00080.1 - 0.0004 19.9 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Mito_carr PF00153.22 EGE00081.1 - 7.2e-68 224.3 3.3 1.3e-21 76.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TauD PF02668.11 EGE00082.1 - 1.9e-59 201.4 0.0 2.7e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EGE00082.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 CsiD PhyH PF05721.8 EGE00082.1 - 0.12 12.4 0.0 0.86 9.5 0.0 2.1 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Glutaredoxin PF00462.19 EGE00083.1 - 2.2e-18 65.9 0.0 1e-16 60.6 0.0 2.5 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EGE00083.1 - 8.4e-13 47.9 0.0 2.1e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGE00083.1 - 0.0022 18.0 0.0 0.058 13.5 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like ArsC PF03960.10 EGE00083.1 - 0.044 13.8 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 ArsC family OPT PF03169.10 EGE00084.1 - 2.6e-168 561.3 50.1 1.3e-151 506.1 28.8 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein DUF4191 PF13829.1 EGE00084.1 - 0.11 11.5 1.1 0.33 10.0 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) RNase_T PF00929.19 EGE00085.1 - 2.2e-23 83.3 0.0 4.9e-23 82.2 0.0 1.6 2 0 0 2 2 2 1 Exonuclease DUF342 PF03961.8 EGE00086.1 - 0.053 11.9 0.0 0.075 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 EGE00086.1 - 0.067 12.8 0.1 6.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SlyX PF04102.7 EGE00086.1 - 0.076 13.4 1.1 9.5 6.6 0.1 3.0 3 0 0 3 3 3 0 SlyX Menin PF05053.8 EGE00086.1 - 0.23 9.5 3.8 0.26 9.4 2.7 1.3 1 0 0 1 1 1 0 Menin Beta_elim_lyase PF01212.16 EGE00087.1 - 3.7e-67 226.5 0.0 5.2e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGE00087.1 - 0.05 12.6 0.1 1 8.3 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EGE00087.1 - 0.099 10.9 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CN_hydrolase PF00795.17 EGE00088.1 - 2.7e-31 108.3 0.1 3.5e-31 107.9 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pkinase PF00069.20 EGE00090.1 - 1.9e-70 237.0 0.0 2.6e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE00090.1 - 1.4e-33 116.0 0.0 2.1e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGE00090.1 - 3.7e-09 36.5 0.2 3.5e-08 33.4 0.1 2.5 2 0 0 2 2 2 1 FHA domain RIO1 PF01163.17 EGE00090.1 - 0.0067 15.7 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EGE00090.1 - 0.007 15.3 0.0 0.017 14.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Peptidase_M28 PF04389.12 EGE00092.1 - 6e-17 61.9 0.0 1.1e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EGE00092.1 - 2.1e-15 56.4 0.0 3.5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EGE00092.1 - 4.2e-07 29.5 0.4 1.5e-05 24.6 0.1 2.6 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EGE00092.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Glyco_transf_34 PF05637.7 EGE00093.1 - 9.2e-62 208.6 0.0 1.4e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF566 PF04484.7 EGE00093.1 - 3.4 7.1 11.2 5.2 6.4 7.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) NDUFB10 PF10249.4 EGE00094.1 - 0.0043 17.1 0.0 0.0046 17.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 BRO1 PF03097.13 EGE00095.1 - 3.9e-10 39.0 0.0 6e-10 38.4 0.0 1.4 1 1 0 1 1 1 1 BRO1-like domain TAFII55_N PF04658.8 EGE00096.1 - 1.7e-51 173.9 0.1 8.1e-51 171.7 0.0 2.0 2 0 0 2 2 2 1 TAFII55 protein conserved region Bromo_TP PF07524.8 EGE00097.1 - 2.9e-10 39.7 0.0 4.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated LysM PF01476.15 EGE00098.1 - 1.3e-09 37.7 1.9 3.4e-06 26.8 0.0 4.0 4 0 0 4 4 4 2 LysM domain Ank_2 PF12796.2 EGE00100.1 - 5.6e-55 183.6 0.0 1.6e-14 53.9 0.0 4.8 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EGE00100.1 - 7.6e-38 126.4 7.9 8.4e-05 22.1 0.0 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 EGE00100.1 - 3.7e-28 97.3 2.9 5.7e-05 23.5 0.0 6.5 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE00100.1 - 1.6e-27 92.7 4.5 0.0031 17.6 0.0 9.9 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.1 EGE00100.1 - 6.4e-25 86.6 7.5 0.0033 17.6 0.0 9.3 2 2 7 9 9 9 6 Ankyrin repeats (many copies) F-box-like PF12937.2 EGE00100.1 - 0.061 13.0 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like FAD_binding_7 PF03441.9 EGE00102.1 - 1.6e-98 329.3 0.2 2.4e-98 328.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EGE00102.1 - 2e-40 138.2 0.1 4.3e-40 137.1 0.1 1.6 1 0 0 1 1 1 1 DNA photolyase RelB_N PF12910.2 EGE00102.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal GFA PF04828.9 EGE00103.1 - 5.7e-18 64.6 1.2 6.9e-18 64.3 0.8 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2757 PF10955.3 EGE00103.1 - 0.00061 19.9 0.7 0.00085 19.4 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2757) DZR PF12773.2 EGE00103.1 - 0.038 13.8 2.2 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 Double zinc ribbon Lipocalin_4 PF13648.1 EGE00103.1 - 0.06 13.9 0.1 0.072 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipocalin-like domain APH PF01636.18 EGE00104.1 - 2e-14 53.8 0.0 9.9e-14 51.6 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGE00104.1 - 0.0055 15.8 0.0 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EGE00104.1 - 0.0056 15.3 0.1 0.043 12.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) adh_short PF00106.20 EGE00106.1 - 3.6e-09 36.7 0.0 5.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE00106.1 - 5.2e-07 29.5 0.0 8.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGE00106.1 - 0.0075 16.0 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_tran_WecB PF03808.8 EGE00106.1 - 0.093 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Peptidase_M36 PF02128.10 EGE00107.1 - 7.7e-163 541.7 4.2 9.5e-163 541.4 2.9 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGE00107.1 - 1.3e-13 50.1 1.2 2.7e-13 49.1 0.9 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 EGE00107.1 - 0.036 14.0 0.1 0.42 10.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M14 PF00246.19 EGE00108.1 - 1.3e-19 70.9 0.0 1.9e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 EGE00108.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.9 EGE00108.1 - 0.05 12.4 0.0 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Aldo_ket_red PF00248.16 EGE00109.1 - 5.5e-54 182.9 0.0 7.1e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_1c PF00749.16 EGE00110.1 - 6.2e-88 294.4 0.0 1e-87 293.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGE00110.1 - 4.5e-34 117.6 0.1 6.7e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EGE00110.1 - 0.0067 16.8 0.0 0.02 15.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_3 PF00933.16 EGE00111.1 - 3.9e-57 193.5 0.0 5.5e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EGE00111.1 - 3.3e-17 62.2 0.1 2.8e-08 33.6 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE00111.1 - 1.4e-14 54.0 0.0 1.3e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGE00111.1 - 9.2e-11 41.8 0.0 6.6e-06 26.2 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGE00111.1 - 3.4e-07 30.1 0.0 0.016 15.0 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 EGE00111.1 - 9.4e-07 28.5 0.0 2.5e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain FR47 PF08445.5 EGE00111.1 - 5.1e-05 22.9 0.1 0.065 12.9 0.0 2.7 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_CG PF14542.1 EGE00111.1 - 0.0002 21.1 0.1 0.036 13.9 0.1 3.2 3 0 0 3 3 3 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.1 EGE00111.1 - 0.063 13.2 0.7 7.2 6.5 0.0 3.0 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain PDEase_I PF00233.14 EGE00112.1 - 6.7e-22 78.3 0.1 4.3e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_L10 PF00466.15 EGE00113.1 - 2.5e-26 91.4 0.2 6.1e-26 90.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EGE00113.1 - 3.1e-11 43.5 0.7 1.2e-10 41.6 0.1 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein WD40 PF00400.27 EGE00114.1 - 3.2e-07 29.9 1.2 0.0013 18.4 0.5 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat URO-D PF01208.12 EGE00115.1 - 1.7e-124 415.2 0.0 1.9e-124 415.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) CTDII PF01556.13 EGE00116.1 - 1.1e-22 79.7 0.1 3.1e-20 71.8 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EGE00116.1 - 1.1e-20 73.1 2.1 1.7e-20 72.4 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGE00116.1 - 4.4e-13 49.0 18.1 7.9e-13 48.2 12.5 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGE00116.1 - 0.24 11.1 9.9 0.38 10.4 1.6 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Sulfate_transp PF00916.15 EGE00118.1 - 3.7e-71 239.4 12.0 3.7e-71 239.4 8.3 1.9 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGE00118.1 - 2.3e-31 107.2 3.1 2.3e-31 107.2 2.1 3.2 4 1 1 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGE00118.1 - 3.6e-07 29.6 0.0 6.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF2072 PF09845.4 EGE00118.1 - 0.19 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) MFS_1 PF07690.11 EGE00119.1 - 6.9e-31 107.2 61.5 3.9e-27 94.9 37.2 3.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGE00119.1 - 2.2e-13 49.3 11.5 4.4e-13 48.3 8.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGE00119.1 - 0.0016 16.8 7.0 0.0016 16.8 4.8 3.7 1 1 3 4 4 4 1 MFS/sugar transport protein DUF1191 PF06697.7 EGE00119.1 - 0.078 11.7 0.0 0.41 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) DSBA PF01323.15 EGE00120.1 - 6.3e-32 110.7 0.0 7.8e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EGE00120.1 - 0.00025 21.0 0.4 0.0033 17.4 0.0 2.1 2 1 0 2 2 2 1 Thioredoxin Rab5ip PF07019.7 EGE00121.1 - 4.3e-10 39.5 3.6 3.9e-09 36.5 0.3 2.1 2 0 0 2 2 2 2 Rab5-interacting protein (Rab5ip) SAPS PF04499.10 EGE00122.1 - 6.3 5.3 18.3 0.14 10.7 0.4 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DnaJ PF00226.26 EGE00123.1 - 9.7e-14 50.8 0.0 3.1e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain HXXEE PF13787.1 EGE00123.1 - 1.2 9.5 5.7 0.64 10.3 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif INO80_Ies4 PF08193.6 EGE00124.1 - 3e-54 184.3 30.9 4e-54 183.9 21.4 1.3 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Adaptin_binding PF10199.4 EGE00124.1 - 0.01 16.1 7.4 0.096 12.9 1.5 2.2 2 0 0 2 2 2 2 Alpha and gamma adaptin binding protein p34 Ycf1 PF05758.7 EGE00124.1 - 0.46 8.1 3.3 0.56 7.8 2.3 1.1 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 EGE00124.1 - 2.6 7.3 18.8 1.5 8.1 11.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CLTH PF10607.4 EGE00125.1 - 5.7e-36 123.3 0.0 1.1e-35 122.5 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EGE00125.1 - 9.4e-22 77.4 0.2 1.7e-21 76.5 0.2 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EGE00125.1 - 0.0044 16.7 0.5 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 LisH TPR_11 PF13414.1 EGE00126.1 - 2.9e-10 39.6 3.1 0.00013 21.5 0.0 4.2 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 EGE00126.1 - 3.1e-10 39.1 10.3 0.0073 16.1 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGE00126.1 - 3.4e-09 35.8 0.1 0.027 14.2 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGE00126.1 - 1.6e-08 33.7 4.0 0.0028 17.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGE00126.1 - 1.3e-07 31.4 11.3 0.0024 17.7 0.5 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGE00126.1 - 1.7e-06 27.3 4.9 0.24 11.2 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 EGE00126.1 - 0.00028 20.9 0.0 0.001 19.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EGE00126.1 - 0.0011 18.6 0.0 0.0031 17.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.1 EGE00126.1 - 0.0041 17.6 0.7 8.2 7.3 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGE00126.1 - 0.0056 16.9 0.0 4.7 7.6 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2075 PF09848.4 EGE00126.1 - 0.034 13.1 0.1 0.17 10.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TPR_16 PF13432.1 EGE00126.1 - 0.04 14.6 0.3 2.9 8.6 0.0 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat AAA_22 PF13401.1 EGE00126.1 - 0.04 14.0 0.0 0.4 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain TPR_17 PF13431.1 EGE00126.1 - 0.045 13.9 0.1 0.94 9.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EGE00126.1 - 0.28 11.3 6.7 1.5 9.0 0.8 3.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EGE00126.1 - 0.81 10.2 17.6 0.54 10.8 0.3 5.5 7 0 0 7 7 4 0 Tetratricopeptide repeat Glyco_hydro_16 PF00722.16 EGE00127.1 - 6.5e-11 41.8 0.0 1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nuc_N PF14448.1 EGE00127.1 - 0.013 15.0 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Nuclease N terminal DUF4328 PF14219.1 EGE00127.1 - 0.11 11.7 0.3 0.22 10.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) IDO PF01231.13 EGE00128.1 - 3.5e-42 144.3 0.0 5.3e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase bcl-2I13 PF12201.3 EGE00128.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing TPR_11 PF13414.1 EGE00129.1 - 1.7e-10 40.3 8.8 1.9e-06 27.4 1.5 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGE00129.1 - 9.5e-10 37.6 8.4 0.031 14.1 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGE00129.1 - 1.9e-06 27.6 5.5 2.8e-05 23.9 0.8 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat F-box PF00646.28 EGE00129.1 - 2.5e-06 26.9 0.0 7.5e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain TPR_16 PF13432.1 EGE00129.1 - 5.5e-06 26.9 9.8 0.00017 22.1 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGE00129.1 - 1.3e-05 24.6 5.9 0.18 11.4 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat F-box-like PF12937.2 EGE00129.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGE00129.1 - 0.0089 15.6 2.8 2.5 7.8 0.0 4.6 3 2 0 3 3 3 1 Leucine Rich repeats (2 copies) TPR_7 PF13176.1 EGE00129.1 - 0.016 14.9 7.6 2.1 8.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EGE00129.1 - 0.06 13.2 1.9 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain LRR_6 PF13516.1 EGE00129.1 - 0.064 13.3 0.0 7 7.0 0.0 4.0 3 0 0 3 3 3 0 Leucine Rich repeat TPR_14 PF13428.1 EGE00129.1 - 0.068 13.8 15.0 1.5 9.6 1.0 4.6 3 1 2 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGE00129.1 - 0.11 12.8 7.6 1.4 9.3 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EGE00129.1 - 0.22 11.6 4.6 1.6 8.8 0.1 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 LRR_8 PF13855.1 EGE00129.1 - 0.77 9.5 6.5 11 5.8 0.0 4.7 3 1 3 6 6 5 0 Leucine rich repeat TPR_3 PF07720.7 EGE00129.1 - 1.5 8.6 5.2 3.9 7.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGE00129.1 - 3.1 7.7 7.5 0.76 9.6 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGE00129.1 - 4.6 7.9 12.0 2.3 8.8 1.7 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Glucosamine_iso PF01182.15 EGE00131.1 - 5.7e-59 199.1 0.0 6.7e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF605 PF04652.11 EGE00132.1 - 8.3 5.6 24.6 11 5.2 17.1 1.2 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 EGE00133.1 - 1.7e-27 94.2 12.0 4.1e-08 32.8 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat SET PF00856.23 EGE00134.1 - 5.4e-07 30.0 0.4 0.0094 16.2 0.0 3.3 3 0 0 3 3 3 2 SET domain TPR_11 PF13414.1 EGE00134.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 TPR repeat zf-MYND PF01753.13 EGE00134.1 - 0.083 12.7 6.0 0.25 11.2 4.2 1.9 1 0 0 1 1 1 0 MYND finger DUF4179 PF13786.1 EGE00135.1 - 0.09 13.0 0.2 0.17 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) LdpA_C PF12617.3 EGE00136.1 - 0.22 10.7 0.1 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal RabGAP-TBC PF00566.13 EGE00137.1 - 4e-32 111.4 0.0 2.9e-31 108.6 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EGE00138.1 - 3.4e-14 51.3 1.5 8.5e-06 25.2 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EGE00138.1 - 4.4e-13 47.5 1.2 1.4e-05 24.0 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGE00138.1 - 6.2e-13 48.6 4.0 6.7e-10 38.9 0.5 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGE00138.1 - 3.5e-09 35.5 3.7 0.00057 19.1 0.5 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EGE00138.1 - 1.1e-06 28.1 0.2 0.037 13.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 EGE00138.1 - 0.043 13.7 0.0 9.5 6.2 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain Afi1 PF07792.7 EGE00139.1 - 9.6e-42 142.4 0.4 1.8e-41 141.5 0.3 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EGE00139.1 - 4.1e-37 126.3 0.0 6.8e-37 125.6 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EGE00139.1 - 9.2e-08 30.9 0.0 0.048 12.1 0.0 3.5 2 1 1 3 3 3 3 Transport protein Avl9 DUF2347 PF09804.4 EGE00139.1 - 0.076 12.2 0.0 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Peripla_BP_6 PF13458.1 EGE00139.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Formyl_trans_N PF00551.14 EGE00140.1 - 8.1e-37 126.5 0.0 9.5e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase 2-ph_phosp PF04029.9 EGE00140.1 - 0.0056 15.6 0.0 0.021 13.7 0.0 1.7 2 0 0 2 2 2 1 2-phosphosulpholactate phosphatase Ribosomal_L7Ae PF01248.21 EGE00141.1 - 1.1e-25 88.9 0.0 1.3e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_1 PF00076.17 EGE00143.1 - 3.4e-18 65.0 0.0 2.8e-13 49.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE00143.1 - 1.9e-11 43.7 0.0 5e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE00143.1 - 4.5e-05 23.2 0.0 0.00012 21.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGE00143.1 - 8.3e-05 22.2 0.0 0.00093 18.9 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 DUF3915 PF13054.1 EGE00145.1 - 2 8.3 5.8 0.38 10.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) MIF4G PF02854.14 EGE00146.1 - 1.2e-26 93.4 1.3 1.4e-26 93.2 0.1 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EGE00146.1 - 6.9e-24 83.7 0.1 2.2e-23 82.1 0.0 1.9 2 0 0 2 2 2 1 MA3 domain NOA36 PF06524.7 EGE00146.1 - 5.4 6.1 7.9 9 5.4 5.5 1.3 1 0 0 1 1 1 0 NOA36 protein DPM2 PF07297.7 EGE00147.1 - 8.4e-16 58.0 0.0 1.1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4229 PF14012.1 EGE00147.1 - 0.0056 16.5 0.1 0.0062 16.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) DUF4083 PF13314.1 EGE00147.1 - 0.023 14.5 0.1 0.026 14.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) COX14 PF14880.1 EGE00147.1 - 0.023 14.2 0.1 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly PIG-P PF08510.7 EGE00147.1 - 0.042 13.4 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 PIG-P HD PF01966.17 EGE00149.1 - 0.00054 19.9 0.0 0.0062 16.5 0.0 2.5 2 1 0 2 2 2 1 HD domain Macoilin PF09726.4 EGE00150.1 - 5.6 5.1 9.1 6.2 4.9 6.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Arrestin_N PF00339.24 EGE00151.1 - 4.3e-12 46.1 2.6 1.6e-06 27.9 0.0 3.8 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EGE00151.1 - 0.01 15.0 0.0 0.039 13.1 0.0 1.9 3 0 0 3 3 3 0 Bul1 C terminus Mem_trans PF03547.13 EGE00152.1 - 1.2 7.2 5.2 1.8 6.7 3.6 1.3 1 0 0 1 1 1 0 Membrane transport protein Pyr_redox_2 PF07992.9 EGE00153.1 - 6.7e-28 97.9 0.0 1.3e-27 97.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGE00153.1 - 1.8e-18 66.7 0.4 4.8e-15 55.7 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EGE00153.1 - 5.4e-14 51.5 0.0 2.3e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EGE00153.1 - 1.3e-13 51.4 0.0 5.7e-07 29.8 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGE00153.1 - 1.6e-06 27.2 0.0 0.01 14.7 0.0 2.5 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGE00153.1 - 5.8e-06 26.1 0.4 0.071 12.8 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Reductase_C PF14759.1 EGE00153.1 - 8.2e-06 26.0 0.0 2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_7 PF13241.1 EGE00153.1 - 0.00076 19.6 0.3 0.23 11.7 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 EGE00153.1 - 0.0028 16.1 0.6 1.6 7.1 0.0 2.5 3 0 0 3 3 3 2 HI0933-like protein DUF1188 PF06690.6 EGE00153.1 - 0.012 14.7 0.1 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) TrkA_N PF02254.13 EGE00153.1 - 0.076 13.0 0.2 4.9 7.1 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain SAM_2 PF07647.12 EGE00154.1 - 2.5e-08 33.6 0.0 4.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGE00154.1 - 0.00013 22.0 0.6 0.00024 21.1 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DHC_N1 PF08385.7 EGE00154.1 - 0.4 8.9 4.9 0.37 9.1 0.7 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 ADIP PF11559.3 EGE00155.1 - 9.7e-38 129.4 11.6 9.7e-38 129.4 8.0 2.3 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding RasGAP_C PF03836.10 EGE00155.1 - 0.12 12.0 9.7 1.3 8.6 0.7 2.7 1 1 0 2 2 2 0 RasGAP C-terminus AAA_13 PF13166.1 EGE00155.1 - 0.13 10.6 6.1 0.22 9.9 4.2 1.3 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EGE00155.1 - 0.14 11.7 15.5 0.53 9.8 0.1 2.2 2 0 0 2 2 2 0 IncA protein Fib_alpha PF08702.5 EGE00155.1 - 0.31 11.1 13.1 0.077 13.1 5.6 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.3 EGE00155.1 - 1.1 8.5 10.5 0.58 9.3 5.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.6 EGE00155.1 - 1.7 7.2 16.0 0.16 10.5 7.7 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 EGE00155.1 - 3.9 7.9 7.3 2.4 8.5 2.3 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal bZIP_1 PF00170.16 EGE00155.1 - 4.9 7.2 16.7 0.9 9.5 0.4 5.0 4 1 0 4 4 4 0 bZIP transcription factor dUTPase PF00692.14 EGE00156.1 - 2e-42 143.7 0.0 2.4e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 dUTPase Phos_pyr_kin PF08543.7 EGE00157.1 - 6.2e-12 45.2 0.0 1.1e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EGE00157.1 - 3.7e-08 32.8 0.1 1.4e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase BON PF04972.12 EGE00157.1 - 0.18 11.5 1.1 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 BON domain PQ-loop PF04193.9 EGE00158.1 - 3.4e-32 109.7 18.5 1.4e-17 62.9 0.9 2.8 3 0 0 3 3 3 2 PQ loop repeat DUF3429 PF11911.3 EGE00158.1 - 0.025 14.5 2.9 0.049 13.6 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) ERGIC_N PF13850.1 EGE00158.1 - 0.032 14.2 0.1 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2776 PF10951.3 EGE00158.1 - 0.91 8.5 8.0 7.4 5.5 2.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2776) zf-HC5HC2H_2 PF13832.1 EGE00159.1 - 1.7e-24 85.9 0.7 1.7e-24 85.9 0.5 3.3 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGE00159.1 - 3.1e-23 81.7 2.6 3.1e-23 81.7 1.8 3.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EGE00159.1 - 1.8e-08 33.5 3.4 1.8e-08 33.5 2.3 4.2 4 0 0 4 4 4 1 PHD-finger PHD PF00628.24 EGE00159.1 - 5.3e-07 29.2 7.4 5.3e-07 29.2 5.1 4.6 5 0 0 5 5 5 2 PHD-finger C1_1 PF00130.17 EGE00159.1 - 0.0045 16.6 2.8 0.0045 16.6 1.9 5.2 5 1 1 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 EGE00159.1 - 0.025 14.5 25.1 0.32 11.0 5.4 3.1 2 0 0 2 2 2 0 RING-like domain GATA PF00320.22 EGE00159.1 - 5.8 6.3 19.7 0.38 10.1 0.7 4.8 4 0 0 4 4 4 0 GATA zinc finger BAH PF01426.13 EGE00160.1 - 4.7e-15 55.3 0.0 8.1e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 BAH domain Ndc1_Nup PF09531.5 EGE00161.1 - 0.13 10.6 1.8 0.16 10.3 1.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.11 EGE00161.1 - 0.28 11.0 1.5 0.32 10.8 1.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 EGE00161.1 - 0.97 7.3 6.0 1 7.3 4.1 1.0 1 0 0 1 1 1 0 CDC45-like protein eIF-3_zeta PF05091.7 EGE00161.1 - 1.6 7.2 6.2 1.7 7.2 4.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) JAB PF01398.16 EGE00162.1 - 1.5e-14 53.6 0.0 2.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EGE00162.1 - 4.6e-07 29.3 0.0 8.7e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TBCC PF07986.7 EGE00163.1 - 2.4e-25 88.2 1.1 4.9e-25 87.2 0.4 1.7 2 0 0 2 2 2 1 Tubulin binding cofactor C GGDN PF05165.7 EGE00163.1 - 0.067 12.2 0.5 0.14 11.1 0.1 1.7 2 0 0 2 2 2 0 GGDN family CDK5_activator PF03261.10 EGE00163.1 - 7.2 5.8 8.7 13 4.9 6.0 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DivIVA PF05103.8 EGE00164.1 - 0.00084 19.4 24.2 0.083 12.9 5.5 3.7 3 1 1 4 4 4 2 DivIVA protein HAP1_N PF04849.8 EGE00164.1 - 1.1 8.1 29.5 0.65 8.8 0.1 2.8 2 1 0 2 2 2 0 HAP1 N-terminal conserved region HR1 PF02185.11 EGE00164.1 - 1.7 8.4 19.1 0.84 9.4 0.3 3.7 2 1 1 3 3 3 0 Hr1 repeat Bap31 PF05529.7 EGE00164.1 - 7 6.0 11.1 2.1 7.7 0.1 2.5 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like V-ATPase_G PF03179.10 EGE00166.1 - 1.6e-34 118.3 15.8 1.9e-34 118.1 10.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EGE00166.1 - 0.0035 17.1 19.0 0.0082 15.9 7.7 2.0 1 1 1 2 2 2 2 ATP synthase B/B' CF(0) HypD PF01924.11 EGE00166.1 - 0.074 11.7 1.6 0.088 11.5 1.1 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family Arch_ATPase PF01637.13 EGE00166.1 - 0.15 11.7 6.6 0.17 11.5 4.6 1.0 1 0 0 1 1 1 0 Archaeal ATPase DUF3552 PF12072.3 EGE00166.1 - 0.44 9.7 19.9 0.73 9.0 13.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) HrpE PF06188.7 EGE00166.1 - 0.63 9.7 8.5 3.6 7.3 2.9 2.0 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF2362 PF10154.4 EGE00166.1 - 0.77 8.3 7.0 0.93 8.0 4.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) SAPS PF04499.10 EGE00166.1 - 1.8 7.1 9.5 1.9 7.0 6.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Colicin-DNase PF12639.2 EGE00166.1 - 1.9 8.8 6.3 3.5 7.9 4.4 1.4 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin ATP11 PF06644.6 EGE00166.1 - 3.2 7.1 10.7 3.9 6.8 7.4 1.1 1 0 0 1 1 1 0 ATP11 protein DUF3154 PF11351.3 EGE00166.1 - 4.9 6.9 5.4 8.2 6.1 2.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) vATP-synt_E PF01991.13 EGE00166.1 - 6.2 6.0 18.8 8.1 5.6 8.6 1.9 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit DUF676 PF05057.9 EGE00167.1 - 0.07 12.4 0.0 0.25 10.6 0.0 1.8 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Helicase_C PF00271.26 EGE00168.1 - 8.1e-20 70.4 0.0 2.1e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGE00168.1 - 8.8e-19 67.6 0.0 2.4e-18 66.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGE00168.1 - 7.7e-18 64.9 0.0 1.7e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EGE00168.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) F_actin_cap_B PF01115.12 EGE00169.1 - 4.3e-106 353.5 0.0 4.9e-106 353.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Med11 PF10280.4 EGE00170.1 - 1.6e-33 115.1 0.0 2e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein WD40 PF00400.27 EGE00171.1 - 4.9e-58 191.0 24.4 8.3e-11 41.3 1.4 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EGE00171.1 - 1.2e-42 145.3 0.0 1.9e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EGE00171.1 - 2.9e-07 29.0 0.5 0.00021 19.5 0.1 3.3 3 1 0 3 3 3 2 Nucleoporin Nup120/160 LisH PF08513.6 EGE00171.1 - 3e-07 29.9 0.0 8.8e-07 28.4 0.0 1.9 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.6 EGE00171.1 - 0.00034 19.5 0.1 2.2 6.9 0.0 3.8 2 1 1 3 3 3 2 Nup133 N terminal like Abhydrolase_6 PF12697.2 EGE00172.1 - 1.3e-23 84.1 0.4 1.9e-23 83.5 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE00172.1 - 3.1e-09 36.7 0.1 5.9e-09 35.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE00172.1 - 7.8e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EGE00172.1 - 0.01 16.0 0.0 0.03 14.5 0.0 1.8 1 1 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 EGE00172.1 - 0.027 14.0 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2417 PF10329.4 EGE00173.1 - 2.2e-81 272.6 0.7 3e-81 272.2 0.5 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EGE00173.1 - 8.7e-08 32.3 0.6 1.4e-07 31.5 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Scs3p PF10261.4 EGE00173.1 - 0.0067 15.4 0.4 0.42 9.6 0.6 2.2 2 0 0 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM Pox_A9 PF04835.7 EGE00173.1 - 0.024 14.5 1.8 4.9 7.1 0.1 2.6 2 0 0 2 2 2 0 A9 protein conserved region DUF2975 PF11188.3 EGE00173.1 - 0.12 12.1 13.6 0.29 10.8 2.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) PMSR PF01625.16 EGE00174.1 - 1.3e-57 194.0 0.5 1.4e-57 193.9 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Pro_dh PF01619.13 EGE00176.1 - 4.3e-30 104.7 0.1 1e-18 67.3 0.0 2.2 2 0 0 2 2 2 2 Proline dehydrogenase GFA PF04828.9 EGE00177.1 - 0.0019 18.1 0.7 0.0043 16.9 0.5 1.7 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_16 PF00722.16 EGE00178.1 - 1.3e-41 141.9 2.4 1.8e-41 141.4 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Alk_phosphatase PF00245.15 EGE00179.1 - 9e-113 377.1 0.0 1.1e-112 376.8 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EGE00179.1 - 9.8e-05 21.8 0.0 0.00029 20.3 0.0 1.7 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 EGE00179.1 - 0.024 14.4 0.1 0.069 12.8 0.0 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF498 PF04430.9 EGE00180.1 - 9.5e-29 99.1 0.0 1.3e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) ABC_tran PF00005.22 EGE00181.1 - 1.5e-33 115.9 0.0 3.7e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGE00181.1 - 8e-24 84.4 8.4 8e-24 84.4 5.8 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EGE00181.1 - 6.2e-08 32.1 0.4 2e-05 23.9 0.0 2.9 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGE00181.1 - 0.00029 20.8 0.0 0.14 12.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGE00181.1 - 0.0039 17.0 0.3 0.043 13.7 0.2 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EGE00181.1 - 0.0079 15.6 0.2 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGE00181.1 - 0.014 14.6 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGE00181.1 - 0.018 15.1 0.1 0.12 12.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGE00181.1 - 0.029 14.3 1.9 0.084 12.8 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain DUF1673 PF07895.6 EGE00181.1 - 0.12 11.8 4.3 1.1 8.7 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) WD40 PF00400.27 EGE00183.1 - 3.8e-24 83.6 12.7 5.9e-10 38.6 0.3 7.2 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 EGE00183.1 - 0.0018 18.0 0.0 0.26 10.9 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EGE00183.1 - 0.041 12.6 4.9 0.22 10.2 0.2 2.6 2 1 1 3 3 3 0 Nup133 N terminal like Fork_head PF00250.13 EGE00184.1 - 1.2e-14 54.1 0.2 2.1e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 Fork head domain Cactin_mid PF10312.4 EGE00185.1 - 1.4e-66 223.4 4.2 2.5e-66 222.6 2.9 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EGE00185.1 - 1.1e-54 183.3 5.3 1.8e-54 182.6 3.7 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein XLF PF09302.6 EGE00186.1 - 3.4e-27 95.2 0.1 5.7e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 XLF (XRCC4-like factor) Ribosomal_L34e PF01199.13 EGE00187.1 - 9.7e-37 125.0 4.1 1.4e-36 124.5 2.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 EGE00187.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) FhuF_C PF11575.3 EGE00187.1 - 0.37 10.4 2.8 6.1 6.5 0.2 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain PROCN PF08083.6 EGE00188.1 - 4.1e-193 641.4 11.8 8.6e-129 429.5 2.6 2.4 1 1 1 2 2 2 2 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EGE00188.1 - 1e-125 417.6 2.9 1.7e-125 416.9 2.0 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EGE00188.1 - 2.2e-101 335.9 0.4 3.7e-65 218.1 0.2 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EGE00188.1 - 1.7e-77 258.2 3.2 1.8e-77 258.1 1.1 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EGE00188.1 - 1.8e-66 221.8 0.2 3.9e-66 220.7 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 EGE00188.1 - 8.9e-54 182.4 2.4 4.3e-53 180.2 0.0 2.5 2 0 0 2 2 2 1 Hom_end-associated Hint PROCT PF08084.6 EGE00188.1 - 1.8e-46 156.9 1.0 3.2e-46 156.1 0.1 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 EGE00188.1 - 4.9e-45 151.3 0.2 1.4e-44 149.9 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end PF05204.9 EGE00188.1 - 0.0057 16.5 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 Homing endonuclease DUF3753 PF12575.3 EGE00188.1 - 0.074 12.8 0.0 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) OCD_Mu_crystall PF02423.10 EGE00188.1 - 0.37 9.4 0.7 0.65 8.7 0.5 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family APH PF01636.18 EGE00189.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family CTP_synth_N PF06418.9 EGE00190.1 - 1.2e-100 336.1 0.0 1.6e-100 335.7 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EGE00190.1 - 5.4e-54 182.5 0.0 8.4e-54 181.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGE00190.1 - 1.6e-06 27.7 0.0 4.8e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 Myb_DNA-bind_6 PF13921.1 EGE00192.1 - 5.6e-08 32.7 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGE00192.1 - 0.00014 21.8 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain COX5B PF01215.14 EGE00194.1 - 6.7e-40 135.9 0.0 9.1e-40 135.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 EGE00194.1 - 0.033 13.6 0.1 0.88 9.1 0.0 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Myb_DNA-binding PF00249.26 EGE00197.1 - 3.6e-13 49.3 4.5 1.4e-07 31.4 1.8 3.0 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGE00197.1 - 4.7e-11 42.6 3.1 1.2e-06 28.4 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain PAT1 PF09770.4 EGE00197.1 - 2 6.5 34.9 2.4 6.2 24.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EGE00197.1 - 5.3 6.8 19.9 6.6 6.5 13.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myb_DNA-bind_6 PF13921.1 EGE00199.1 - 0.002 18.1 0.1 0.0039 17.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGE00199.1 - 0.0029 17.6 0.2 0.0049 16.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rrn6 PF10214.4 EGE00199.1 - 0.052 11.6 1.9 0.066 11.2 1.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CAF1-p150_N PF15557.1 EGE00202.1 - 0.039 13.2 0.1 0.052 12.8 0.1 1.1 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to PCNA Myb_DNA-bind_4 PF13837.1 EGE00203.1 - 0.0029 17.7 3.4 0.011 15.7 0.9 2.4 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain PXPV PF12778.2 EGE00203.1 - 0.067 12.8 2.1 0.12 12.0 1.5 1.3 1 0 0 1 1 1 0 PXPV repeat (3 copies) eRF1_3 PF03465.10 EGE00204.1 - 6.6e-18 65.0 0.0 1.1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EGE00204.1 - 1.6e-17 64.1 0.0 3.3e-16 59.8 0.0 2.2 1 1 0 1 1 1 1 eRF1 domain 2 ATP_bind_1 PF03029.12 EGE00205.1 - 2.1e-39 135.5 0.2 2.4e-39 135.2 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein S-AdoMet_synt_C PF02773.11 EGE00206.1 - 8.7e-77 255.4 1.8 1.2e-76 254.9 0.2 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EGE00206.1 - 1.3e-48 163.8 0.0 2.2e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EGE00206.1 - 3.6e-13 49.5 0.4 1.3e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain SLD3 PF08639.5 EGE00207.1 - 2.8e-114 382.4 9.8 5.9e-114 381.4 6.8 1.5 1 1 0 1 1 1 1 DNA replication regulator SLD3 CRC_subunit PF08624.5 EGE00209.1 - 3.7e-55 185.6 0.2 5.2e-55 185.1 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit AT_hook PF02178.14 EGE00209.1 - 0.81 9.5 6.9 2.9 7.8 4.3 2.4 1 1 1 2 2 2 0 AT hook motif APH PF01636.18 EGE00210.1 - 1.6e-12 47.6 0.2 2.3e-12 47.1 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE00210.1 - 0.0016 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EGE00210.1 - 0.025 13.2 0.0 0.032 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Homeobox PF00046.24 EGE00212.1 - 1.9e-16 59.4 1.5 1.6e-15 56.4 1.9 1.9 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EGE00212.1 - 0.00011 21.8 0.5 0.00028 20.5 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Rota_VP2 PF05087.7 EGE00212.1 - 4.5 5.0 4.4 6.2 4.6 3.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein HAD_2 PF13419.1 EGE00215.1 - 6.7e-17 62.2 0.0 8.8e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGE00215.1 - 5.3e-10 40.0 0.0 9.7e-08 32.6 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGE00215.1 - 7.8e-08 31.9 0.1 1.9e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 EGE00215.1 - 0.00042 20.5 0.0 0.00058 20.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EGE00215.1 - 0.0025 17.6 0.1 0.082 12.8 0.0 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.6 EGE00216.1 - 2.2e-25 88.3 16.9 5.1e-25 87.1 11.7 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EGE00216.1 - 7e-22 77.5 0.2 4.4e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGE00216.1 - 8.9e-06 25.6 6.6 0.14 11.9 1.0 3.9 2 2 1 3 3 3 2 Dynamin family FeoB_N PF02421.13 EGE00216.1 - 9.3e-06 25.0 0.1 6.9e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGE00216.1 - 6.8e-05 22.3 0.2 0.2 11.0 0.1 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGE00216.1 - 0.00014 21.0 0.1 0.00024 20.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EGE00216.1 - 0.00041 20.8 0.2 1.6 9.2 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AIG1 PF04548.11 EGE00216.1 - 0.012 14.6 0.3 0.047 12.7 0.1 1.9 2 0 0 2 2 2 0 AIG1 family ArgK PF03308.11 EGE00216.1 - 0.018 13.8 0.1 0.04 12.7 0.1 1.5 1 0 0 1 1 1 0 ArgK protein cobW PF02492.14 EGE00216.1 - 0.021 14.2 0.1 1.1 8.6 0.0 2.8 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EGE00216.1 - 0.036 14.3 2.4 0.065 13.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EGE00216.1 - 0.099 12.3 0.1 0.26 10.9 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGE00216.1 - 0.19 11.7 3.2 0.82 9.6 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.1 EGE00216.1 - 1.3 8.5 3.9 25 4.3 1.8 2.5 3 0 0 3 3 3 0 AAA domain CBFD_NFYB_HMF PF00808.18 EGE00217.1 - 5.9e-06 26.2 0.0 9.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.5 EGE00217.1 - 0.14 11.2 23.9 0.18 10.8 16.6 1.1 1 0 0 1 1 1 0 BUD22 DUF4407 PF14362.1 EGE00217.1 - 1.1 8.1 10.1 1.5 7.6 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SIR2 PF02146.12 EGE00218.1 - 1.1e-25 90.4 0.0 4.1e-25 88.5 0.0 1.9 1 1 0 1 1 1 1 Sir2 family FAD_binding_4 PF01565.18 EGE00218.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Med16 PF11635.3 EGE00219.1 - 4.2e-155 517.7 0.0 5e-155 517.4 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Ribosomal_L29 PF00831.18 EGE00220.1 - 2.1e-18 65.7 0.4 2.1e-18 65.7 0.2 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein Pox_polyA_pol_N PF12630.2 EGE00220.1 - 0.1 12.7 0.6 0.14 12.2 0.3 1.4 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Cortex-I_coil PF09304.5 EGE00220.1 - 0.14 12.1 8.1 0.093 12.7 1.6 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil Phe_tRNA-synt_N PF02912.13 EGE00220.1 - 0.29 10.8 0.1 0.29 10.8 0.1 2.5 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain FliT PF05400.8 EGE00220.1 - 1.5 9.2 5.6 2.3 8.6 0.1 2.3 2 1 0 2 2 2 0 Flagellar protein FliT V-SNARE_C PF12352.3 EGE00221.1 - 9.3e-16 57.6 7.9 2.8e-15 56.1 0.1 3.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.1 EGE00221.1 - 0.033 12.6 7.4 0.045 12.2 5.2 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 AAA_13 PF13166.1 EGE00221.1 - 0.033 12.6 1.8 0.043 12.2 1.2 1.3 1 0 0 1 1 1 0 AAA domain Sec20 PF03908.8 EGE00221.1 - 0.039 13.6 4.9 4.9 6.9 0.0 3.1 2 1 0 3 3 3 0 Sec20 DivIC PF04977.10 EGE00221.1 - 0.041 13.3 7.5 0.49 9.9 0.6 3.2 2 1 1 3 3 3 0 Septum formation initiator IncA PF04156.9 EGE00221.1 - 0.081 12.5 11.5 0.17 11.4 8.0 1.5 1 0 0 1 1 1 0 IncA protein TBPIP PF07106.8 EGE00221.1 - 0.11 12.0 6.4 0.091 12.2 3.4 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 EGE00221.1 - 0.17 10.4 5.8 0.28 9.7 4.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Cep57_MT_bd PF06657.8 EGE00221.1 - 0.19 11.7 6.7 1.1 9.2 0.5 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 APG6 PF04111.7 EGE00221.1 - 0.2 10.7 5.3 0.25 10.3 3.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 EGE00221.1 - 0.4 10.4 9.5 0.53 10.0 1.4 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 EGE00221.1 - 0.48 10.6 3.5 2.8 8.1 0.3 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF342 PF03961.8 EGE00221.1 - 0.53 8.6 3.8 0.63 8.4 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) FTA4 PF13093.1 EGE00221.1 - 0.56 9.5 9.0 17 4.7 7.2 2.0 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 YgaB PF14182.1 EGE00221.1 - 0.66 10.2 3.5 24 5.2 0.0 2.9 2 1 0 2 2 2 0 YgaB-like protein GAS PF13851.1 EGE00221.1 - 0.71 9.0 7.7 1.6 7.8 5.3 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.6 EGE00221.1 - 1.1 9.7 7.2 4.1 7.8 3.9 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Snf7 PF03357.16 EGE00221.1 - 2 7.7 7.1 2.6 7.3 3.6 1.9 1 1 1 2 2 2 0 Snf7 SlyX PF04102.7 EGE00221.1 - 2.1 8.7 6.1 9.3 6.7 0.2 3.5 2 1 2 4 4 4 0 SlyX V_ATPase_I PF01496.14 EGE00221.1 - 2.2 6.0 4.1 5.6 4.6 2.8 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 EGE00221.1 - 3.6 7.1 6.1 2.5 7.7 0.2 2.2 1 1 1 2 2 2 0 Mnd1 family DUF3552 PF12072.3 EGE00221.1 - 3.7 6.7 9.4 2.6 7.2 5.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) ATP-synt_10 PF05176.9 EGE00222.1 - 7.8e-80 267.7 0.0 1e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DNA_pol_B_palm PF14792.1 EGE00223.1 - 1.8e-30 105.2 0.0 3.5e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EGE00223.1 - 1.9e-20 72.3 0.0 3.9e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EGE00223.1 - 7e-19 67.1 2.6 1.4e-18 66.1 0.3 2.6 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EGE00223.1 - 1.8e-16 60.0 0.6 4.2e-16 58.8 0.4 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EGE00223.1 - 0.02 15.1 0.1 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH_5 PF14520.1 EGE00223.1 - 0.031 14.4 1.0 16 5.7 0.0 2.8 2 1 0 2 2 2 0 Helix-hairpin-helix domain BRCT PF00533.21 EGE00223.1 - 0.047 13.8 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Zn_clus PF00172.13 EGE00224.1 - 0.0045 16.8 9.3 0.011 15.6 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPL PF08144.6 EGE00226.1 - 5.9e-18 65.1 0.0 1.2e-16 60.8 0.0 2.9 3 0 0 3 3 3 1 CPL (NUC119) domain DUF2890 PF11081.3 EGE00226.1 - 0.0032 17.5 13.5 0.0032 17.5 9.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2890) DUF2457 PF10446.4 EGE00226.1 - 0.083 11.6 19.8 0.13 10.9 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 EGE00226.1 - 0.14 10.5 24.1 0.27 9.6 16.7 1.5 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EGE00226.1 - 0.37 8.6 27.6 0.57 8.0 19.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGE00226.1 - 0.56 8.1 19.0 0.9 7.4 13.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EGE00226.1 - 0.7 9.1 29.4 1.9 7.7 20.4 1.7 1 0 0 1 1 1 0 SDA1 ESSS PF10183.4 EGE00228.1 - 1.6 9.1 4.0 1.7 9.1 0.3 2.4 2 1 1 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Rad51 PF08423.6 EGE00229.1 - 2.5e-138 459.1 0.0 3.2e-138 458.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EGE00229.1 - 6.9e-13 48.4 0.0 9.8e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EGE00229.1 - 3.2e-07 30.4 0.3 1.1e-06 28.6 0.2 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 EGE00229.1 - 6.8e-07 28.6 0.0 9.1e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EGE00229.1 - 2.4e-05 23.5 0.1 6e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 KaiC HHH PF00633.18 EGE00229.1 - 0.018 14.7 0.5 6.7 6.6 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif DnaB_C PF03796.10 EGE00229.1 - 0.038 12.8 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EGE00229.1 - 0.045 12.5 0.1 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.3 EGE00230.1 - 2.8e-131 438.3 8.8 3.9e-131 437.8 6.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_12 PF13424.1 EGE00230.1 - 0.019 14.8 0.7 0.1 12.5 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGE00230.1 - 0.13 13.0 2.3 0.19 12.4 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.11 EGE00231.1 - 3.6e-38 131.2 29.3 3.6e-38 131.2 20.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE00231.1 - 3e-07 29.3 6.5 3e-07 29.3 4.5 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EGE00231.1 - 4.3e-06 25.2 2.5 4.3e-06 25.2 1.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3808 PF10300.4 EGE00232.1 - 1.6e-140 468.8 0.0 1.9e-140 468.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.8 EGE00233.1 - 1e-22 79.6 12.3 1.4e-22 79.2 8.6 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.14 EGE00234.1 - 1.6e-148 494.3 0.2 1.9e-148 494.1 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase zf-H2C2_2 PF13465.1 EGE00235.1 - 8.9e-09 35.2 8.1 2.7e-07 30.5 0.4 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGE00235.1 - 2.5e-08 33.7 4.8 4.5e-05 23.5 0.3 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE00235.1 - 5.4e-05 23.2 6.3 0.0004 20.4 0.2 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGE00235.1 - 0.0036 17.1 0.2 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE00235.1 - 0.091 12.9 4.2 1.1 9.4 0.3 3.5 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EGE00235.1 - 0.16 12.0 3.6 0.77 9.9 0.4 2.4 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SNF2_N PF00176.18 EGE00236.1 - 6.1e-65 218.9 0.2 3.3e-64 216.5 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EGE00236.1 - 1.8e-23 81.9 0.3 2.4e-13 49.5 0.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 EGE00236.1 - 6e-19 68.1 0.3 4.5e-18 65.3 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 EGE00236.1 - 1e-11 44.5 0.0 3.4e-11 42.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE00236.1 - 9.4e-06 25.5 0.0 6.4e-05 22.8 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGE00236.1 - 0.0045 17.1 0.0 0.023 14.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain DUF3972 PF13118.1 EGE00236.1 - 0.008 16.2 1.4 0.021 14.8 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3972) ABC_tran PF00005.22 EGE00237.1 - 5.1e-35 120.7 0.0 1.4e-15 57.7 0.0 3.3 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EGE00237.1 - 2.4e-13 50.6 4.5 0.073 13.0 0.0 4.9 3 2 2 5 5 5 4 AAA domain SMC_N PF02463.14 EGE00237.1 - 2.9e-11 43.0 2.6 0.0027 16.9 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain RLI PF04068.10 EGE00237.1 - 3.5e-07 29.6 1.6 3.5e-07 29.6 1.1 2.1 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_15 PF13175.1 EGE00237.1 - 2e-06 27.1 0.1 1.9 7.4 0.0 4.4 4 1 0 5 5 5 1 AAA ATPase domain AAA_17 PF13207.1 EGE00237.1 - 4.6e-06 27.4 0.3 0.1 13.4 0.0 3.2 3 2 0 3 3 2 2 AAA domain AAA PF00004.24 EGE00237.1 - 1.2e-05 25.5 0.1 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGE00237.1 - 5.2e-05 23.3 0.0 0.017 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.22 EGE00237.1 - 7.4e-05 22.1 2.5 7.4e-05 22.1 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.10 EGE00237.1 - 7.9e-05 21.5 0.0 0.13 10.9 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 EGE00237.1 - 8.3e-05 22.0 0.4 0.063 12.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EGE00237.1 - 0.00016 21.9 0.0 0.41 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGE00237.1 - 0.00022 20.4 0.0 0.66 9.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EGE00237.1 - 0.00036 20.6 0.0 0.2 11.8 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.1 EGE00237.1 - 0.00077 18.9 0.1 0.32 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 EGE00237.1 - 0.00077 18.9 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E MobB PF03205.9 EGE00237.1 - 0.00086 19.0 2.1 0.1 12.2 0.0 3.0 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_21 PF14697.1 EGE00237.1 - 0.001 18.8 8.3 0.0019 17.9 5.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain NACHT PF05729.7 EGE00237.1 - 0.0014 18.3 2.4 0.081 12.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 EGE00237.1 - 0.0014 18.2 0.5 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EGE00237.1 - 0.0015 18.8 0.1 0.091 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGE00237.1 - 0.002 18.1 0.2 0.51 10.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EGE00237.1 - 0.0023 17.7 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EGE00237.1 - 0.0026 17.2 2.9 0.052 12.9 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.2 EGE00237.1 - 0.0094 15.7 2.1 0.0094 15.7 1.5 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Thymidylate_kin PF02223.12 EGE00237.1 - 0.012 15.0 0.1 4.8 6.5 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase Fer4_10 PF13237.1 EGE00237.1 - 0.013 15.2 1.3 0.013 15.2 0.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Miro PF08477.8 EGE00237.1 - 0.013 15.9 0.0 0.86 10.1 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein Fer4_16 PF13484.1 EGE00237.1 - 0.018 15.7 2.9 0.054 14.2 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_5 PF07728.9 EGE00237.1 - 0.021 14.5 0.1 0.94 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EGE00237.1 - 0.035 12.9 0.4 10 4.8 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain Fer4_8 PF13183.1 EGE00237.1 - 0.037 14.0 6.9 0.12 12.4 4.9 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.1 EGE00237.1 - 0.047 13.2 0.3 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EGE00237.1 - 0.088 12.7 0.1 6.8 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EGE00237.1 - 0.093 12.6 0.1 14 5.7 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EGE00237.1 - 0.098 11.1 0.4 0.2 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EGE00237.1 - 0.15 11.1 0.1 0.33 10.0 0.1 1.5 1 0 0 1 1 1 0 KaiC Fer4_17 PF13534.1 EGE00237.1 - 0.15 12.4 0.2 0.15 12.4 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 EGE00237.1 - 0.17 12.2 9.7 0.64 10.4 6.9 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain PduV-EutP PF10662.4 EGE00237.1 - 0.17 11.3 0.1 0.17 11.3 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EGE00237.1 - 0.18 11.3 2.3 0.84 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.1 EGE00237.1 - 0.19 12.0 11.0 0.05 13.8 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.10 EGE00237.1 - 0.2 11.3 2.0 7.4 6.2 0.1 2.6 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 EGE00237.1 - 0.3 9.9 0.8 1.3 7.8 0.0 2.3 3 0 0 3 3 3 0 Type II/IV secretion system protein Fer4_2 PF12797.2 EGE00237.1 - 5.6 7.0 9.3 0.54 10.2 1.9 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.14 EGE00238.1 - 1.2e-58 194.8 15.4 1.1e-14 54.1 0.0 7.0 6 1 0 6 6 6 5 FF domain WW PF00397.21 EGE00238.1 - 9.3e-19 66.9 9.4 1.3e-09 37.7 0.5 2.6 2 0 0 2 2 2 2 WW domain HycH PF07450.6 EGE00238.1 - 0.11 12.5 0.3 0.32 11.0 0.2 1.8 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Trs65 PF12735.2 EGE00239.1 - 2.2e-78 263.6 0.1 2.2e-78 263.6 0.1 1.4 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.7 EGE00240.1 - 1.2e-21 76.0 0.1 3.4e-21 74.6 0.1 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.11 EGE00241.1 - 1.2e-29 103.1 32.3 1.9e-28 99.2 20.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1616 PF07760.6 EGE00241.1 - 0.18 10.8 4.7 0.046 12.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) p450 PF00067.17 EGE00243.1 - 5.7e-62 209.7 0.0 6.3e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4485 PF14846.1 EGE00243.1 - 0.26 11.0 1.3 2.6 7.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4485) Amidase PF01425.16 EGE00244.1 - 1.8e-80 271.0 0.0 2.4e-80 270.5 0.0 1.1 1 0 0 1 1 1 1 Amidase Arm PF00514.18 EGE00245.1 - 8.2e-94 304.6 9.5 1.2e-14 53.4 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGE00245.1 - 5.8e-25 87.3 0.1 4.7e-10 39.6 0.0 5.6 1 1 5 6 6 6 4 HEAT repeats IBB PF01749.15 EGE00245.1 - 6.7e-23 80.6 0.9 1.1e-22 79.9 0.6 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EGE00245.1 - 6.2e-20 69.4 0.1 6.8e-06 25.7 0.0 6.7 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.1 EGE00245.1 - 1.5e-19 69.8 8.0 5.3e-09 36.3 0.0 6.2 4 1 3 7 7 7 3 HEAT-like repeat Arm_2 PF04826.8 EGE00245.1 - 1.3e-09 37.6 0.0 0.0026 16.9 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 EGE00245.1 - 1.2e-05 23.9 0.0 0.003 15.9 0.0 3.0 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EGE00245.1 - 6.6e-05 22.8 0.0 3.1 7.7 0.0 4.6 3 2 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.11 EGE00245.1 - 0.00043 20.4 1.5 0.73 10.4 0.0 4.7 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 EGE00245.1 - 0.0035 15.6 0.0 0.12 10.5 0.0 2.5 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.1 EGE00245.1 - 0.0052 16.6 0.6 2.2 8.2 0.0 4.1 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.4 EGE00245.1 - 0.066 12.9 0.0 12 5.6 0.0 3.3 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain POT1 PF02765.12 EGE00246.1 - 6.3e-13 48.8 0.0 4.7e-12 46.0 0.0 2.3 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 TRAP_alpha PF03896.11 EGE00248.1 - 8e-11 41.4 0.0 8.4e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit HA2 PF04408.18 EGE00249.1 - 4.7e-18 65.1 0.0 1.1e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGE00249.1 - 1.9e-16 59.9 0.0 3.6e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGE00249.1 - 5.2e-12 45.4 0.0 1.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 EGE00249.1 - 3.1e-11 43.1 0.1 6.7e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EGE00249.1 - 8e-10 38.4 0.1 1.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGE00249.1 - 0.00023 21.2 0.1 0.00075 19.6 0.1 1.9 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.1 EGE00249.1 - 0.003 17.8 0.0 0.0079 16.4 0.0 1.8 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.1 EGE00249.1 - 0.0051 16.3 0.0 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 EGE00249.1 - 0.0051 15.7 0.0 0.0094 14.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein CoA_trans PF01144.18 EGE00249.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase AAA_25 PF13481.1 EGE00249.1 - 0.022 14.1 0.0 0.05 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGE00249.1 - 0.023 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 EGE00249.1 - 0.025 14.9 0.0 0.089 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain UBA PF00627.26 EGE00249.1 - 0.079 12.8 0.0 1.1 9.1 0.0 2.9 3 0 0 3 3 3 0 UBA/TS-N domain AAA_19 PF13245.1 EGE00249.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF4258 PF14076.1 EGE00249.1 - 0.11 12.5 0.1 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) DUF4129 PF13559.1 EGE00250.1 - 0.0025 17.7 0.0 0.0081 16.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Bac_transf PF02397.11 EGE00250.1 - 0.15 11.1 0.1 0.41 9.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial sugar transferase GCFC PF07842.7 EGE00251.1 - 9.9e-86 287.5 7.5 1.6e-85 286.8 5.2 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EGE00251.1 - 8.8e-16 57.4 0.4 1.7e-15 56.5 0.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGE00251.1 - 1.7e-07 30.9 0.1 6.8e-07 29.0 0.1 2.1 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF4320 PF14208.1 EGE00251.1 - 0.19 11.7 0.1 0.44 10.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) Sod_Fe_C PF02777.13 EGE00252.1 - 2.6e-39 133.3 0.2 4.2e-39 132.6 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGE00252.1 - 4.1e-30 103.8 0.9 6.7e-30 103.1 0.6 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Spc7 PF08317.6 EGE00253.1 - 0.071 11.7 13.4 0.057 12.0 8.3 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Microtub_assoc PF07989.6 EGE00253.1 - 1.3 8.9 14.8 0.44 10.3 2.0 2.5 1 1 1 2 2 2 0 Microtubule associated IncA PF04156.9 EGE00253.1 - 7.1 6.1 19.6 13 5.3 13.6 1.4 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EGE00253.1 - 8.2 5.3 18.5 14 4.6 12.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Sld5 PF05916.6 EGE00254.1 - 2.6e-16 59.8 0.0 3.4e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein NOA36 PF06524.7 EGE00255.1 - 0.31 10.2 5.9 0.68 9.1 4.1 1.5 1 0 0 1 1 1 0 NOA36 protein ABC_tran_2 PF12848.2 EGE00256.1 - 0.13 12.1 0.1 0.13 12.1 0.0 2.7 3 0 0 3 3 3 0 ABC transporter PH_10 PF15411.1 EGE00258.1 - 1.1e-35 122.3 0.0 2.4e-31 108.3 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain CDC24 PF06395.6 EGE00258.1 - 6.3e-34 115.9 0.0 1.9e-33 114.3 0.0 1.8 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.15 EGE00258.1 - 2.4e-30 105.7 0.9 4.5e-30 104.8 0.6 1.5 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EGE00258.1 - 1.5e-07 30.9 0.0 3.8e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.27 EGE00259.1 - 2e-39 132.0 12.9 4.2e-07 29.5 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EGE00259.1 - 6.2e-12 45.0 0.2 1.2e-11 44.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE00259.1 - 1.4e-07 30.9 0.1 3.8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 EGE00259.1 - 0.0021 17.8 0.1 2.3 8.0 0.0 3.6 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EGE00259.1 - 0.18 9.8 0.8 5.3 5.0 0.1 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Uds1 PF15456.1 EGE00261.1 - 7.9e-41 138.9 1.9 7.9e-41 138.9 1.3 6.4 4 2 2 6 6 6 1 Up-regulated During Septation TMF_DNA_bd PF12329.3 EGE00261.1 - 3.6e-05 23.4 10.9 3.6e-05 23.4 7.5 9.3 10 1 1 11 11 11 3 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 EGE00261.1 - 0.0033 15.9 41.3 0.14 10.5 12.0 3.6 2 1 2 4 4 4 3 AAA domain LINES_N PF14694.1 EGE00261.1 - 0.8 8.9 11.0 0.037 13.2 0.9 2.5 1 1 1 2 2 2 0 Lines N-terminus Vac_Fusion PF02346.11 EGE00261.1 - 3.6 7.0 11.4 10 5.6 1.1 3.8 3 0 0 3 3 3 0 Chordopoxvirus fusion protein APG6 PF04111.7 EGE00261.1 - 4.8 6.1 63.0 0.0078 15.2 5.7 5.5 3 1 2 5 5 5 0 Autophagy protein Apg6 IncA PF04156.9 EGE00261.1 - 5.4 6.5 84.8 0.039 13.5 2.1 7.0 3 2 3 6 6 6 0 IncA protein WEMBL PF05701.6 EGE00261.1 - 8.7 4.6 62.1 1.5 7.1 5.2 3.3 2 1 1 3 3 3 0 Weak chloroplast movement under blue light MFS_1 PF07690.11 EGE00262.1 - 3.3e-24 85.2 32.3 4.7e-24 84.7 22.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UCR_hinge PF02320.11 EGE00263.1 - 3.3e-24 84.5 4.3 3.6e-24 84.4 3.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 EGE00263.1 - 3.3 7.6 5.5 19 5.1 3.8 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) WWbp PF10349.4 EGE00264.1 - 7.8e-16 58.9 0.5 1.7e-15 57.8 0.3 1.6 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EGE00264.1 - 9.1e-05 22.1 0.0 0.039 13.7 0.0 2.2 1 1 1 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EGE00264.1 - 0.019 14.4 0.0 0.04 13.4 0.0 1.5 1 1 0 1 1 1 0 GRAM domain DUF1929 PF09118.6 EGE00264.1 - 0.051 13.6 1.1 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1929) DUF3439 PF11921.3 EGE00264.1 - 0.25 11.1 7.5 0.34 10.6 4.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 EGE00264.1 - 0.51 8.0 3.8 0.65 7.6 2.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 EGE00264.1 - 2.3 6.0 10.2 3.4 5.5 7.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 EGE00264.1 - 4.8 6.9 15.4 7.8 6.2 10.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Acyltransferase PF01553.16 EGE00267.1 - 1.8e-10 40.3 0.0 0.00011 21.6 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Prenyltransf PF01255.14 EGE00268.1 - 8.9e-81 270.2 0.0 1.4e-80 269.6 0.0 1.3 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Saccharop_dh PF03435.13 EGE00269.1 - 1.4e-124 415.9 0.0 3e-124 414.9 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EGE00269.1 - 7.5e-06 26.0 0.2 1.2e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EGE00269.1 - 2.4e-05 24.4 0.7 0.0042 17.1 0.1 2.2 2 0 0 2 2 2 2 NADH(P)-binding NAD_binding_7 PF13241.1 EGE00269.1 - 0.022 14.9 0.1 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2325 PF10087.4 EGE00269.1 - 0.042 13.6 0.1 0.17 11.7 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) 3Beta_HSD PF01073.14 EGE00269.1 - 0.12 11.1 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N_2 PF13602.1 EGE00270.1 - 6e-22 78.8 0.0 1.1e-21 77.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EGE00270.1 - 2.8e-15 56.0 0.3 4.7e-15 55.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EGE00270.1 - 0.0026 17.8 0.2 0.0048 16.9 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding ADH_N PF08240.7 EGE00270.1 - 0.0071 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PGM_PMM_II PF02879.11 EGE00270.1 - 0.046 14.0 0.0 0.19 12.0 0.0 2.0 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Glyco_hydro_15 PF00723.16 EGE00271.1 - 1.5e-93 313.8 0.1 1.8e-93 313.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EGE00271.1 - 1.5e-28 98.2 0.0 3.8e-28 96.9 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain Antitoxin-MazE PF04014.13 EGE00271.1 - 0.049 13.3 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Antidote-toxin recognition MazE Aha1_N PF09229.6 EGE00272.1 - 2.7e-38 130.8 0.4 4.5e-38 130.1 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EGE00272.1 - 1e-16 61.1 0.1 2.1e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Mucin PF01456.12 EGE00272.1 - 2.4 7.9 16.2 4.2 7.1 11.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein FBPase PF00316.15 EGE00275.1 - 2e-120 401.5 0.0 2.3e-120 401.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase OAD_gamma PF04277.8 EGE00276.1 - 0.03 14.6 0.3 0.099 13.0 0.2 2.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Shisa PF13908.1 EGE00276.1 - 0.2 11.7 4.3 0.076 13.1 0.5 1.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF912 PF06024.7 EGE00276.1 - 1.1 9.3 4.1 0.41 10.7 0.9 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Fungal_trans_2 PF11951.3 EGE00277.1 - 4.6e-40 137.4 0.2 5.9e-40 137.0 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE00277.1 - 1.9e-07 30.8 11.1 3e-07 30.2 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase-like PF12876.2 EGE00277.1 - 0.1 13.0 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like E1-E2_ATPase PF00122.15 EGE00278.1 - 8.9e-64 214.6 3.9 8.9e-64 214.6 2.7 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGE00278.1 - 9.2e-31 107.9 0.0 1.6e-29 103.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EGE00278.1 - 8.2e-26 90.6 6.8 8.2e-26 90.6 4.7 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EGE00278.1 - 2.2e-16 59.5 0.0 5.8e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGE00278.1 - 2.2e-15 55.8 0.0 5.5e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGE00278.1 - 2.5e-13 50.6 0.0 6.3e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGE00278.1 - 0.0012 18.4 0.7 0.014 14.9 0.9 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HlyIII PF03006.15 EGE00279.1 - 2.6e-29 102.2 15.4 3.2e-29 101.9 10.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF3325 PF11804.3 EGE00279.1 - 1.8 8.5 8.4 0.34 10.8 2.7 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3325) Sugar_tr PF00083.19 EGE00280.1 - 3.5e-79 266.4 24.6 4.3e-79 266.2 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE00280.1 - 3.1e-22 78.7 46.9 6.3e-16 58.0 11.7 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGE00280.1 - 3.1 5.7 12.6 1.9 6.4 0.1 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family V_ATPase_I PF01496.14 EGE00281.1 - 3.3e-293 974.2 0.6 3.7e-293 974.1 0.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1515 PF07439.6 EGE00281.1 - 0.0013 18.5 0.2 0.0039 16.9 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) CheZ PF04344.8 EGE00281.1 - 0.19 11.3 4.4 0.67 9.5 0.0 2.5 3 0 0 3 3 3 0 Chemotaxis phosphatase, CheZ DUF869 PF05911.6 EGE00281.1 - 0.29 9.3 3.7 0.39 8.8 0.7 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) IncA PF04156.9 EGE00281.1 - 0.31 10.6 4.6 0.53 9.8 1.6 2.2 2 0 0 2 2 2 0 IncA protein DUF3552 PF12072.3 EGE00281.1 - 0.46 9.6 4.9 5.5 6.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Filament PF00038.16 EGE00281.1 - 0.53 9.6 10.0 2.3 7.6 0.1 2.5 2 1 0 2 2 2 0 Intermediate filament protein DivIC PF04977.10 EGE00281.1 - 0.75 9.3 3.3 1.1 8.7 0.2 2.8 3 0 0 3 3 3 0 Septum formation initiator YlqD PF11068.3 EGE00281.1 - 1.1 9.2 5.3 1.3 9.0 1.1 2.4 2 1 1 3 3 3 0 YlqD protein CCDC-167 PF15188.1 EGE00281.1 - 2.2 8.2 5.2 7.8 6.5 2.3 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF342 PF03961.8 EGE00281.1 - 2.5 6.4 5.0 0.71 8.2 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) MOSC PF03473.12 EGE00282.1 - 0.0022 17.4 0.3 0.0057 16.1 0.2 1.8 1 1 0 1 1 1 1 MOSC domain DUF3437 PF11919.3 EGE00283.1 - 2e-30 104.3 0.0 6.4e-30 102.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EGE00283.1 - 0.0056 16.6 0.2 2.7 8.3 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EGE00283.1 - 0.017 15.3 0.0 7.4 6.9 0.0 4.0 3 0 0 3 3 3 0 HEAT repeats Mannosyl_trans2 PF04188.8 EGE00284.1 - 4.7e-43 147.7 15.1 1.8e-41 142.4 10.4 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) DBD_Tnp_Hermes PF10683.4 EGE00285.1 - 0.1 12.0 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain Peptidase_S8 PF00082.17 EGE00286.1 - 1.9e-47 161.7 1.5 2.3e-47 161.5 1.0 1.0 1 0 0 1 1 1 1 Subtilase family FixQ PF05545.6 EGE00287.1 - 0.032 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ PepSY_TM_2 PF13703.1 EGE00287.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM helix YL1 PF05764.8 EGE00287.1 - 2 7.9 4.9 2.6 7.5 3.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Metallophos PF00149.23 EGE00288.1 - 6.4e-08 32.2 1.3 0.0037 16.6 0.0 2.8 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE00288.1 - 1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PX PF00787.19 EGE00289.1 - 1.3e-18 66.8 0.4 3.2e-18 65.5 0.3 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EGE00289.1 - 1.7e-13 50.4 5.3 1.5e-06 27.6 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like DUF1664 PF07889.7 EGE00289.1 - 0.056 13.2 1.3 2.7 7.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 EGE00289.1 - 0.11 12.2 6.5 10 6.0 0.3 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding BAR PF03114.13 EGE00289.1 - 0.4 10.1 5.6 2.9 7.3 3.9 2.1 1 1 0 1 1 1 0 BAR domain V_ATPase_I PF01496.14 EGE00289.1 - 9.7 3.9 6.3 34 2.1 4.4 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2946 PF11162.3 EGE00290.1 - 0.096 12.8 1.2 0.13 12.4 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) FAD_binding_3 PF01494.14 EGE00291.1 - 2.6e-22 79.3 0.0 3e-20 72.5 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EGE00291.1 - 0.00022 20.2 0.0 0.006 15.5 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EGE00291.1 - 0.00061 18.7 0.0 0.018 13.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGE00291.1 - 0.0084 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.5 EGE00291.1 - 0.01 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.9 EGE00291.1 - 0.032 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGE00291.1 - 0.05 13.6 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGE00291.1 - 0.062 12.2 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGE00291.1 - 0.086 12.8 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain tRNA-synt_His PF13393.1 EGE00292.1 - 6.6e-38 130.5 0.0 8.6e-32 110.4 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EGE00292.1 - 5.5e-18 65.1 0.0 1.4e-17 63.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGE00292.1 - 2.8e-13 49.6 0.0 5.2e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EGE00292.1 - 0.0088 14.8 0.1 0.22 10.2 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Ribosomal_60s PF00428.14 EGE00292.1 - 0.28 11.6 3.2 1.2 9.5 0.1 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein dUTPase PF00692.14 EGE00293.1 - 5.8e-09 35.4 0.0 7.8e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase hNIFK_binding PF12196.3 EGE00293.1 - 0.23 10.8 3.5 0.39 10.1 2.4 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK MIP-T3 PF10243.4 EGE00294.1 - 0.073 11.5 6.7 0.08 11.3 4.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2956 PF11169.3 EGE00294.1 - 0.15 11.9 3.1 0.47 10.4 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) UCH PF00443.24 EGE00295.1 - 2.5e-62 210.4 1.0 2.5e-62 210.4 0.7 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE00295.1 - 7.4e-28 97.8 6.2 4.2e-22 78.9 0.1 3.0 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Ycf1 PF05758.7 EGE00295.1 - 0.44 8.1 10.3 0.0095 13.7 2.5 1.5 2 0 0 2 2 2 0 Ycf1 DUF4557 PF15101.1 EGE00295.1 - 1.4 8.7 9.1 4.6 7.0 6.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF2215 PF10225.4 EGE00295.1 - 3.8 6.9 5.5 7.3 5.9 3.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Borrelia_P83 PF05262.6 EGE00295.1 - 9.6 4.3 18.6 18 3.4 12.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Yos1 PF08571.5 EGE00296.1 - 9.4e-29 99.3 0.1 1.2e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.12 EGE00297.1 - 5e-37 127.9 14.3 6.6e-37 127.4 9.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Dynamitin PF04912.9 EGE00298.1 - 4.3e-32 111.3 2.0 2.2e-15 56.4 0.3 2.2 2 0 0 2 2 2 2 Dynamitin DivIC PF04977.10 EGE00298.1 - 0.0016 17.9 11.9 0.014 14.8 0.6 3.4 3 0 0 3 3 3 1 Septum formation initiator TPR_MLP1_2 PF07926.7 EGE00298.1 - 0.0029 17.3 2.7 0.0029 17.3 1.8 3.5 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 EGE00298.1 - 0.0098 15.5 6.4 0.3 10.6 0.7 3.2 3 0 0 3 3 3 1 IncA protein Prefoldin_2 PF01920.15 EGE00298.1 - 0.018 14.8 9.7 0.18 11.5 0.8 3.4 3 0 0 3 3 3 0 Prefoldin subunit FH2 PF02181.18 EGE00298.1 - 0.036 12.9 2.1 0.09 11.6 0.2 2.4 3 0 0 3 3 3 0 Formin Homology 2 Domain Laminin_II PF06009.7 EGE00298.1 - 0.059 13.1 0.4 0.059 13.1 0.3 2.9 4 1 0 4 4 2 0 Laminin Domain II ADIP PF11559.3 EGE00298.1 - 0.083 12.7 9.8 0.22 11.3 0.3 3.3 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EGE00298.1 - 0.09 12.7 12.2 1.1 9.1 1.9 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) TBPIP PF07106.8 EGE00298.1 - 0.095 12.2 4.2 1.5 8.3 0.3 3.0 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 EGE00298.1 - 0.17 10.9 7.8 1.5 7.8 0.6 2.4 3 0 0 3 3 3 0 Autophagy protein Apg6 Viral_P18 PF04521.8 EGE00298.1 - 0.19 11.1 9.0 2 7.8 0.7 3.4 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein DUF3373 PF11853.3 EGE00298.1 - 0.22 10.0 2.3 3.5 6.0 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3373) AcylCoA_dehyd_C PF12186.3 EGE00298.1 - 0.23 11.3 1.7 5.8 6.8 0.0 2.9 3 0 0 3 3 2 0 Acyl-CoA dehydrogenase C terminal DUF3166 PF11365.3 EGE00298.1 - 0.25 11.8 6.6 0.085 13.3 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) DUF4446 PF14584.1 EGE00298.1 - 0.5 10.1 2.5 5.3 6.8 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF4446) Mnd1 PF03962.10 EGE00298.1 - 0.58 9.8 8.9 2.2 7.8 0.2 2.8 3 0 0 3 3 3 0 Mnd1 family DUF904 PF06005.7 EGE00298.1 - 0.7 10.2 7.9 12 6.2 1.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Spectrin PF00435.16 EGE00298.1 - 0.8 10.0 8.2 19 5.5 1.2 3.4 3 0 0 3 3 3 0 Spectrin repeat LPP PF04728.8 EGE00298.1 - 0.86 9.4 6.7 0.15 11.8 0.2 3.1 4 0 0 4 4 2 0 Lipoprotein leucine-zipper Spc24 PF08286.6 EGE00298.1 - 1 9.1 11.3 1.7 8.3 1.3 3.2 4 0 0 4 4 4 0 Spc24 subunit of Ndc80 DUF3584 PF12128.3 EGE00298.1 - 1.1 6.4 10.8 0.23 8.7 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) COG2 PF06148.6 EGE00298.1 - 1.2 8.9 4.7 2 8.2 0.2 3.1 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4337 PF14235.1 EGE00298.1 - 3 7.6 13.9 1.4 8.7 0.4 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4337) THOC7 PF05615.8 EGE00298.1 - 3.9 7.7 12.2 2.4 8.4 2.8 2.8 3 0 0 3 3 2 0 Tho complex subunit 7 SlyX PF04102.7 EGE00298.1 - 5.1 7.5 13.2 4.2 7.8 0.9 4.4 4 1 0 4 4 4 0 SlyX Vfa1 PF08432.5 EGE00298.1 - 5.7 6.9 9.7 10 6.1 0.3 2.7 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 AAA_13 PF13166.1 EGE00298.1 - 5.7 5.2 5.8 24 3.1 0.7 2.7 2 1 0 3 3 3 0 AAA domain Ax_dynein_light PF10211.4 EGE00298.1 - 7 6.4 11.3 8.6 6.1 0.6 2.9 3 0 0 3 3 3 0 Axonemal dynein light chain MbeD_MobD PF04899.7 EGE00298.1 - 7.6 6.5 7.3 0.73 9.7 0.5 2.7 4 0 0 4 4 3 0 MbeD/MobD like DUF4140 PF13600.1 EGE00298.1 - 8.7 6.8 19.8 3.6 8.0 1.5 4.5 3 2 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) GrpE PF01025.14 EGE00298.1 - 9.1 5.7 9.8 17 4.9 0.8 3.1 3 0 0 3 3 3 0 GrpE Peptidase_M24 PF00557.19 EGE00300.1 - 8.9e-39 133.2 0.3 1.3e-38 132.6 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Aldedh PF00171.17 EGE00301.1 - 4.3e-134 447.3 0.7 6.2e-134 446.7 0.5 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase_C PF00433.19 EGE00301.1 - 0.11 12.9 0.0 0.35 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain Calreticulin PF00262.13 EGE00302.1 - 1.9e-166 553.2 16.3 1.9e-166 553.2 11.3 1.6 2 0 0 2 2 2 1 Calreticulin family DUF2273 PF10031.4 EGE00302.1 - 0.5 10.0 4.4 0.88 9.2 3.0 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Aldolase_II PF00596.16 EGE00303.1 - 1e-40 139.2 0.0 1.2e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.5 EGE00304.1 - 1e-88 296.6 4.7 1.7e-88 295.8 3.3 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EGE00304.1 - 4.1e-25 87.7 0.0 1.1e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 PX domain Ribosomal_60s PF00428.14 EGE00305.1 - 0.03 14.7 4.6 0.056 13.8 3.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Tissue_fac PF01108.12 EGE00305.1 - 0.052 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Tissue factor Flavin_Reduct PF01613.13 EGE00306.1 - 5.3e-25 88.0 1.2 1e-24 87.1 0.9 1.5 1 1 0 1 1 1 1 Flavin reductase like domain Cellulase-like PF12876.2 EGE00306.1 - 0.032 14.6 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF4505 PF14956.1 EGE00306.1 - 0.13 11.9 0.1 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4505) 4HBT_2 PF13279.1 EGE00309.1 - 1.3e-17 64.3 0.0 1.9e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Complex1_LYR_2 PF13233.1 EGE00310.1 - 4.2e-09 36.8 0.5 4.6e-09 36.6 0.3 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 EGE00310.1 - 0.0016 18.6 0.5 0.0022 18.1 0.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGE00310.1 - 0.0018 18.0 0.2 0.0025 17.5 0.1 1.3 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Methyltransf_11 PF08241.7 EGE00311.1 - 1.7e-09 38.0 0.0 3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE00311.1 - 4.2e-09 36.6 0.0 7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE00311.1 - 7.1e-07 28.9 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE00311.1 - 3.5e-06 26.8 0.0 7.3e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE00311.1 - 5.2e-06 25.7 0.0 8.7e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGE00311.1 - 7.7e-05 23.2 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE00311.1 - 0.00011 22.6 0.0 0.0002 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE00311.1 - 0.00031 20.7 0.0 0.00071 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGE00311.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HisG PF01634.13 EGE00311.1 - 0.16 11.5 0.0 17 4.9 0.0 2.1 2 0 0 2 2 2 0 ATP phosphoribosyltransferase MTS PF05175.9 EGE00311.1 - 0.17 11.2 0.0 0.48 9.7 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase small domain Exo_endo_phos PF03372.18 EGE00312.1 - 1.4e-21 77.6 0.0 2.2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EGE00312.1 - 3.7e-14 51.9 9.9 5.1e-08 32.3 1.5 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGE00312.1 - 5.5e-08 32.4 6.7 1.3e-07 31.2 4.3 1.9 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 EGE00312.1 - 1.9e-06 27.1 6.3 0.029 14.3 0.0 4.4 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 EGE00312.1 - 0.00013 21.6 13.0 0.12 12.6 0.0 4.6 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 EGE00312.1 - 0.4 10.9 0.1 0.4 10.9 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeat MFS_1 PF07690.11 EGE00314.1 - 3.3e-44 151.0 48.3 6.7e-44 150.0 32.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGE00314.1 - 1.9e-23 82.5 17.6 5.2e-20 71.1 11.0 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGE00314.1 - 1.6e-19 69.8 0.8 1.6e-19 69.8 0.5 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter Peptidase_M56 PF05569.6 EGE00314.1 - 0.025 13.5 0.2 0.042 12.8 0.2 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF1705 PF08019.7 EGE00314.1 - 0.034 13.6 0.2 0.034 13.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) BatD PF13584.1 EGE00314.1 - 0.9 8.0 2.9 0.6 8.6 0.2 1.9 2 0 0 2 2 2 0 Oxygen tolerance HET PF06985.6 EGE00315.1 - 1.3e-20 73.9 0.1 2.2e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GCD14 PF08704.5 EGE00316.1 - 4e-07 29.7 0.0 0.00071 19.1 0.0 2.4 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EGE00316.1 - 0.0049 16.4 0.0 3.7 7.1 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EGE00316.1 - 0.11 12.5 0.0 1.3 9.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGE00316.1 - 0.13 12.7 0.1 9.5 6.7 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Metallophos PF00149.23 EGE00317.1 - 1.6e-13 50.5 0.7 2.8e-13 49.6 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE00317.1 - 5.2e-05 23.1 0.1 9.1e-05 22.3 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NAD_binding_6 PF08030.7 EGE00318.1 - 3.3e-05 23.8 0.5 0.00058 19.7 0.1 2.5 2 1 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EGE00318.1 - 8.7e-05 23.0 0.0 0.0092 16.5 0.0 2.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain MARVEL PF01284.18 EGE00319.1 - 0.00056 19.7 2.4 0.00081 19.2 1.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF2721 PF11026.3 EGE00319.1 - 1.3 8.6 5.0 15 5.2 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) COesterase PF00135.23 EGE00320.1 - 6.1e-63 213.3 0.0 8.2e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGE00320.1 - 4.4e-07 29.6 0.0 9.6e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold E1-E2_ATPase PF00122.15 EGE00321.1 - 5.3e-52 176.1 0.3 1.2e-51 175.0 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.21 EGE00321.1 - 6.4e-50 167.1 0.0 3.1e-12 46.4 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 EGE00321.1 - 2e-42 146.0 0.7 5e-42 144.7 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGE00321.1 - 6.5e-13 49.2 0.0 2.5e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGE00321.1 - 1.8e-05 24.4 0.0 0.0042 16.7 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase B12-binding PF02310.14 EGE00321.1 - 0.0062 16.4 0.0 7.3 6.4 0.0 4.5 5 0 0 5 5 5 1 B12 binding domain DUF1930 PF09122.5 EGE00321.1 - 0.064 13.0 1.2 22 4.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1930) DUF3133 PF11331.3 EGE00321.1 - 0.074 12.6 3.1 30 4.2 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) PCI PF01399.22 EGE00322.1 - 3.6e-05 24.0 0.0 5.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 PCI domain RGS PF00615.14 EGE00323.1 - 1.1e-12 48.0 0.0 5.8e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Bromodomain PF00439.20 EGE00324.1 - 7.2e-26 89.9 0.8 1.4e-25 89.0 0.6 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EGE00324.1 - 1.3e-09 38.0 0.1 2.7e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE00324.1 - 4.3e-09 36.2 0.1 8.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family UPF0197 PF05251.7 EGE00325.1 - 0.0025 18.0 6.8 0.0064 16.7 4.7 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0197) FA_desaturase PF00487.19 EGE00325.1 - 0.052 12.9 1.4 0.057 12.8 1.0 1.0 1 0 0 1 1 1 0 Fatty acid desaturase Rad1 PF02144.11 EGE00326.1 - 2.3e-90 302.0 0.1 2.7e-90 301.8 0.1 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 SbcCD_C PF13558.1 EGE00327.1 - 1.1e-11 44.5 0.0 3e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EGE00327.1 - 1.6e-08 35.1 131.1 0.00024 21.5 50.2 7.8 1 1 2 3 3 3 1 AAA domain SMC_N PF02463.14 EGE00327.1 - 2.1e-06 27.1 0.0 2.1e-06 27.1 0.0 3.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EGE00327.1 - 6.3e-06 25.5 18.2 6.3e-06 25.5 12.6 4.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.1 EGE00327.1 - 0.00025 19.6 0.0 0.00025 19.6 0.0 7.8 1 1 7 9 9 9 4 AAA domain AAA_29 PF13555.1 EGE00327.1 - 0.0008 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EGE00327.1 - 0.0025 17.8 25.1 0.032 14.1 0.0 4.6 3 2 1 4 4 4 2 AAA domain APG6 PF04111.7 EGE00327.1 - 0.0042 16.1 13.9 0.0042 16.1 9.6 8.3 3 3 6 9 9 9 2 Autophagy protein Apg6 AAA_22 PF13401.1 EGE00327.1 - 0.022 14.9 0.0 0.022 14.9 0.0 5.0 5 2 1 6 6 6 0 AAA domain AAA_16 PF13191.1 EGE00327.1 - 0.095 12.6 0.0 0.095 12.6 0.0 5.0 4 2 1 5 5 5 0 AAA ATPase domain PPP4R2 PF09184.6 EGE00328.1 - 1e-07 31.7 4.1 1e-07 31.7 2.9 2.7 2 1 0 2 2 2 1 PPP4R2 DUF3480 PF11979.3 EGE00329.1 - 0.12 10.9 0.1 4.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3480) zf-H2C2_2 PF13465.1 EGE00330.1 - 4.6e-13 48.7 7.6 1.9e-07 30.9 0.1 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGE00330.1 - 1.4e-11 43.9 13.6 1.3e-05 25.1 1.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE00330.1 - 3.2e-10 39.5 14.0 3.9e-05 23.6 1.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE00330.1 - 8.9e-07 28.8 1.3 0.091 12.9 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGE00330.1 - 0.00014 21.9 1.9 0.011 15.9 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 EGE00330.1 - 0.024 14.8 0.3 0.064 13.5 0.2 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Elf1 PF05129.8 EGE00330.1 - 0.096 12.3 0.7 0.18 11.4 0.5 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.7 EGE00330.1 - 0.11 12.6 1.9 0.22 11.6 1.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EGE00330.1 - 6.7 6.7 8.2 40 4.3 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EGE00330.1 - 9.7 5.9 12.0 1.7 8.3 0.4 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Pkinase PF00069.20 EGE00332.1 - 1.8e-33 115.8 2.5 5.4e-15 55.2 0.1 3.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE00332.1 - 3.9e-16 58.9 0.7 6.1e-15 54.9 0.3 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase zf-C2H2_4 PF13894.1 EGE00334.1 - 3e-10 39.6 11.2 0.00013 22.0 2.4 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE00334.1 - 3.1e-07 30.3 14.9 0.00055 20.1 1.4 3.6 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE00334.1 - 1.1e-05 25.4 12.8 0.011 15.9 0.1 3.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-H2C2_5 PF13909.1 EGE00334.1 - 0.032 14.4 1.0 0.032 14.4 0.7 2.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-Di19 PF05605.7 EGE00334.1 - 0.064 13.3 0.5 0.064 13.3 0.4 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Mfp-3 PF04202.8 EGE00334.1 - 0.096 12.8 0.0 0.096 12.8 0.0 1.6 2 0 0 2 2 2 0 Foot protein 3 SelP_N PF04592.9 EGE00335.1 - 0.13 11.5 13.8 0.23 10.8 9.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2946 PF11162.3 EGE00335.1 - 2.1 8.5 11.8 0.14 12.4 4.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) MAP65_ASE1 PF03999.7 EGE00335.1 - 2.8 6.4 9.6 3.8 5.9 6.6 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Innate_immun PF12782.2 EGE00335.1 - 7.1 5.7 18.3 13 4.9 12.7 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family APH PF01636.18 EGE00336.1 - 8e-41 140.3 0.0 1.3e-40 139.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE00336.1 - 7.8e-05 21.8 0.0 0.0003 19.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EGE00336.1 - 0.0003 20.0 0.0 0.00076 18.6 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 EGE00336.1 - 0.0036 16.3 0.0 0.1 11.5 0.0 2.2 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.17 EGE00336.1 - 0.035 13.4 0.0 0.68 9.2 0.0 2.2 2 0 0 2 2 2 0 RIO1 family DUF3180 PF11377.3 EGE00337.1 - 0.051 13.4 0.4 0.051 13.4 0.3 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3180) DUF2427 PF10348.4 EGE00337.1 - 1.9 8.0 10.0 0.23 11.0 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) ATP-synt_DE_N PF02823.11 EGE00338.1 - 5.7e-18 64.4 0.0 8.7e-18 63.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Ribosomal_L29e PF01779.12 EGE00339.1 - 5.4e-23 80.5 12.5 8.4e-23 79.9 8.7 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family DUF2414 PF10309.4 EGE00340.1 - 3.6e-25 87.3 0.0 6.7e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Cu-oxidase_3 PF07732.10 EGE00341.1 - 7.6e-12 44.9 0.5 7e-08 32.2 0.1 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGE00341.1 - 1.5e-07 30.9 0.2 0.033 13.7 0.0 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGE00341.1 - 0.0045 16.8 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Copper-bind PF00127.15 EGE00341.1 - 0.15 12.3 0.0 0.42 10.8 0.0 1.8 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family ABC_tran PF00005.22 EGE00342.1 - 6.6e-48 162.4 0.0 2.7e-29 102.2 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EGE00342.1 - 1.3e-24 87.0 28.6 7e-18 65.0 4.2 3.9 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 EGE00342.1 - 1.9e-09 37.0 5.1 0.00046 19.4 0.9 4.8 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGE00342.1 - 5.1e-07 29.9 1.2 5.6e-05 23.2 0.0 3.4 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGE00342.1 - 7.8e-07 28.5 0.9 0.0065 15.9 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGE00342.1 - 9.2e-06 25.7 0.3 0.011 15.6 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EGE00342.1 - 3.1e-05 24.4 0.8 0.042 14.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EGE00342.1 - 0.0001 21.8 2.4 0.085 12.2 0.2 2.7 2 1 1 3 3 3 2 AAA-like domain AAA_25 PF13481.1 EGE00342.1 - 0.00014 21.2 0.1 0.39 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 EGE00342.1 - 0.00023 21.0 4.6 0.0054 16.5 0.3 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EGE00342.1 - 0.00037 20.6 0.3 0.7 10.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EGE00342.1 - 0.00046 19.1 0.4 0.7 8.7 0.0 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein SbcCD_C PF13558.1 EGE00342.1 - 0.00096 19.0 0.3 4.8 7.1 0.0 3.8 4 0 0 4 4 3 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EGE00342.1 - 0.0015 19.2 1.7 0.12 13.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EGE00342.1 - 0.0033 16.6 0.1 0.44 9.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EGE00342.1 - 0.004 16.6 0.0 0.75 9.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family CbiA PF01656.18 EGE00342.1 - 0.0087 15.4 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 EGE00342.1 - 0.015 15.5 0.5 0.41 10.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EGE00342.1 - 0.017 15.0 0.4 0.47 10.4 0.2 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 EGE00342.1 - 0.017 14.9 0.0 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EGE00342.1 - 0.05 13.2 0.5 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EGE00342.1 - 0.073 11.8 0.0 0.17 10.6 0.0 1.5 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 EGE00342.1 - 0.12 12.8 0.3 11 6.4 0.1 3.0 3 0 0 3 3 2 0 Miro-like protein NACHT PF05729.7 EGE00342.1 - 0.24 11.0 2.7 15 5.2 0.0 3.5 3 0 0 3 3 3 0 NACHT domain AAA_5 PF07728.9 EGE00342.1 - 8.4 6.1 6.4 32 4.2 0.1 4.2 5 1 1 6 6 5 0 AAA domain (dynein-related subfamily) Myb_DNA-binding PF00249.26 EGE00344.1 - 3.7e-24 84.5 0.6 3.6e-12 46.1 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGE00344.1 - 2.9e-19 68.9 6.2 2e-13 50.2 0.0 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain HTH_23 PF13384.1 EGE00344.1 - 0.056 13.1 0.2 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DUF2774 PF11242.3 EGE00344.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.1 EGE00344.1 - 0.15 12.2 0.0 0.15 12.2 0.0 2.8 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain RAB3GAP2_N PF14655.1 EGE00344.1 - 0.42 9.5 2.3 1.1 8.2 0.3 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BAF1_ABF1 PF04684.8 EGE00344.1 - 8.1 5.1 15.1 16 4.1 10.5 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CATSPERB PF15149.1 EGE00346.1 - 0.079 11.1 0.0 0.082 11.0 0.0 1.0 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family Glyco_transf_41 PF13844.1 EGE00347.1 - 2.7e-71 239.9 0.1 2.4e-50 170.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EGE00347.1 - 1.1e-20 72.9 14.7 1.6e-08 34.0 0.1 4.6 4 0 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 EGE00347.1 - 2.1e-15 55.3 10.7 0.00069 19.3 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGE00347.1 - 2.6e-14 52.0 9.4 0.00071 19.0 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGE00347.1 - 6.6e-11 42.0 8.9 0.00012 21.9 0.2 4.4 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGE00347.1 - 1.6e-10 40.6 6.1 0.0032 17.9 0.1 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGE00347.1 - 3.5e-09 36.1 6.0 0.45 10.8 0.0 6.0 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGE00347.1 - 5.9e-09 36.3 10.2 0.001 19.6 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGE00347.1 - 2.1e-06 27.9 2.7 0.0065 16.7 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EGE00347.1 - 3.9e-05 23.7 0.2 0.016 15.3 0.0 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGE00347.1 - 0.00024 20.6 6.1 1.2 9.1 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGE00347.1 - 0.00034 20.1 10.0 0.044 13.5 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat BTAD PF03704.12 EGE00347.1 - 0.004 17.4 0.6 3.1 8.0 0.2 2.7 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.1 EGE00347.1 - 0.0065 16.8 5.1 2.8 8.6 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGE00347.1 - 0.031 13.3 1.4 2.7 6.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGE00347.1 - 0.072 13.0 15.4 3.5 7.7 0.4 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGE00347.1 - 2.9 7.8 5.3 5.4 6.9 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Ribosomal_L11_N PF03946.9 EGE00350.1 - 1.2e-16 59.9 0.1 1.7e-16 59.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EGE00350.1 - 1e-09 38.3 0.0 1.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.10 EGE00351.1 - 9.1e-78 260.9 0.0 1.3e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGE00351.1 - 2.4e-33 113.6 0.3 5e-33 112.6 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGE00351.1 - 1e-28 99.6 0.0 2.1e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGE00351.1 - 6.1e-16 57.7 4.9 1.2e-15 56.7 3.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGE00351.1 - 1e-10 41.1 0.0 2.5e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat DNA_primase_lrg PF04104.9 EGE00352.1 - 7.1e-82 274.5 0.0 1e-81 274.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Phage_head_chap PF11113.3 EGE00352.1 - 0.11 12.4 0.1 0.41 10.5 0.1 2.0 1 0 0 1 1 1 0 Head assembly gene product ADK PF00406.17 EGE00353.1 - 9.6e-36 122.9 0.0 1.8e-19 70.1 0.0 2.0 1 1 1 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EGE00353.1 - 9.3e-16 57.2 0.0 1.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EGE00353.1 - 0.00015 22.1 0.0 0.0013 19.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGE00353.1 - 0.00069 20.4 0.0 0.0011 19.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGE00353.1 - 0.0028 17.5 0.0 0.013 15.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGE00353.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ArgK PF03308.11 EGE00353.1 - 0.089 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 EGE00353.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain SNase PF00565.12 EGE00354.1 - 1.4e-24 86.3 0.0 2.1e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Mito_carr PF00153.22 EGE00355.1 - 5.1e-57 189.5 2.2 4.2e-22 77.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.16 EGE00356.1 - 8e-26 90.7 0.0 1.3e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EGE00356.1 - 6.5e-17 61.5 0.0 3.8e-13 49.3 0.0 3.1 2 1 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.13 EGE00356.1 - 9.1e-05 22.2 2.3 0.00017 21.4 1.6 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF605 PF04652.11 EGE00357.1 - 1.1e-98 331.0 19.7 1.3e-98 330.8 13.7 1.0 1 0 0 1 1 1 1 Vta1 like DUF812 PF05667.6 EGE00357.1 - 0.022 13.3 2.4 0.035 12.6 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Epimerase PF01370.16 EGE00361.1 - 7.4e-19 68.1 0.0 1.1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGE00361.1 - 2.6e-07 29.8 0.0 3.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EGE00361.1 - 5.3e-07 28.6 0.0 6.4e-06 25.0 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGE00361.1 - 2.1e-05 24.5 0.0 4.4e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EGE00361.1 - 0.00076 19.5 0.1 0.0072 16.3 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EGE00361.1 - 0.029 13.3 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Topoisom_I_N PF02919.10 EGE00362.1 - 1.1e-97 325.4 1.4 1.1e-97 325.4 1.0 3.7 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EGE00362.1 - 4.3e-86 287.8 2.1 4.3e-86 287.8 1.5 2.8 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EGE00362.1 - 1e-12 47.5 11.8 2.9e-12 46.0 3.2 3.1 2 1 0 2 2 2 1 C-terminal topoisomerase domain ATP-synt PF00231.14 EGE00363.1 - 4.8e-70 236.1 3.8 5.6e-70 235.9 2.6 1.0 1 0 0 1 1 1 1 ATP synthase Thioredoxin PF00085.15 EGE00366.1 - 1.5e-28 98.5 0.0 4.6e-24 84.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EGE00366.1 - 4.7e-08 33.2 0.2 0.00018 21.6 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGE00366.1 - 3.7e-06 26.9 0.1 0.0018 18.3 0.0 3.9 3 1 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 EGE00366.1 - 0.0031 17.2 0.0 0.046 13.3 0.0 2.5 3 0 0 3 3 3 1 AhpC/TSA family GNAT_acetyltr_2 PF13718.1 EGE00367.1 - 3.1e-80 268.1 0.0 5.6e-80 267.2 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EGE00367.1 - 1.1e-65 220.5 0.0 2.8e-65 219.2 0.0 1.7 2 0 0 2 2 2 1 Helicase tRNA_bind_2 PF13725.1 EGE00367.1 - 9.1e-36 122.0 0.2 2.5e-35 120.6 0.2 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.6 EGE00367.1 - 6.5e-34 115.4 0.0 2e-33 113.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.19 EGE00367.1 - 0.021 14.8 0.0 0.074 13.0 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE00367.1 - 0.023 14.8 0.0 0.073 13.2 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_90 PF05686.7 EGE00368.1 - 1.3e-14 53.6 0.0 4.8e-07 28.8 0.0 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF2721 PF11026.3 EGE00368.1 - 0.49 10.0 0.0 0.49 10.0 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) Glyco_hydro_16 PF00722.16 EGE00369.1 - 5e-10 38.9 0.0 1.1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Vps8 PF12816.2 EGE00370.1 - 2.9e-71 238.7 1.1 7e-71 237.5 0.1 2.1 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EGE00370.1 - 1.3e-07 31.3 8.2 0.0002 20.9 0.2 4.5 5 1 1 6 6 6 2 Region in Clathrin and VPS Pox_D3 PF04580.8 EGE00370.1 - 0.037 13.2 0.3 0.1 11.7 0.1 1.8 2 0 0 2 2 2 0 Chordopoxvirinae D3 protein zf-RING_2 PF13639.1 EGE00370.1 - 0.19 11.5 3.6 0.24 11.2 0.7 2.5 2 0 0 2 2 2 0 Ring finger domain TPR_12 PF13424.1 EGE00377.1 - 2e-22 78.8 4.2 6.5e-08 32.3 0.1 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat NB-ARC PF00931.17 EGE00377.1 - 4.2e-22 78.3 0.0 8.1e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 EGE00377.1 - 3.6e-08 32.9 1.0 2.9e-05 23.6 0.1 3.7 2 2 3 5 5 5 3 TPR repeat TPR_10 PF13374.1 EGE00377.1 - 5e-08 32.6 9.1 0.0018 18.1 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGE00377.1 - 1.9e-07 30.4 5.2 0.025 14.4 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGE00377.1 - 5.8e-06 25.7 0.6 0.47 10.3 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 EGE00377.1 - 1.9e-05 24.7 0.8 0.0041 17.1 0.5 2.8 1 1 0 1 1 1 1 AAA ATPase domain TPR_1 PF00515.23 EGE00377.1 - 4.7e-05 22.8 0.9 0.03 13.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.1 EGE00377.1 - 4.8e-05 23.5 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.1 EGE00377.1 - 0.00029 21.4 5.4 0.42 11.3 0.3 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.1 EGE00377.1 - 0.0015 17.7 0.2 0.011 14.8 0.0 2.0 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 EGE00377.1 - 0.0017 18.6 2.8 2.5 8.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGE00377.1 - 0.0038 17.5 3.1 19 5.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_14 PF13173.1 EGE00377.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGE00377.1 - 0.05 13.3 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase TPR_14 PF13428.1 EGE00377.1 - 0.11 13.1 11.7 4.5 8.1 0.0 5.8 5 2 1 6 6 6 0 Tetratricopeptide repeat KaiC PF06745.8 EGE00377.1 - 0.18 10.8 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 KaiC DEAD PF00270.24 EGE00378.1 - 6e-41 139.7 1.7 1.1e-40 138.8 0.9 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE00378.1 - 9.5e-23 79.8 0.1 1.3e-11 44.2 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EGE00378.1 - 1.4e-05 24.9 0.0 6e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UPF0154 PF03672.8 EGE00379.1 - 0.018 14.6 0.2 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Acyltransferase PF01553.16 EGE00380.1 - 2.2e-13 49.7 0.0 4.4e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.4 EGE00381.1 - 4.8e-46 155.0 0.9 5.3e-46 154.9 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Pkinase PF00069.20 EGE00383.1 - 4.3e-21 75.2 0.0 1.4e-20 73.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE00383.1 - 1e-06 28.0 0.2 0.0029 16.6 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase CENP-T PF15511.1 EGE00384.1 - 0.024 13.9 0.6 0.023 13.9 0.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Annexin PF00191.15 EGE00386.1 - 5.3e-61 202.4 0.1 1.3e-17 63.3 0.0 4.1 4 0 0 4 4 4 4 Annexin EBP PF05241.7 EGE00387.1 - 3.6e-63 212.1 3.5 4.3e-63 211.8 2.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein HNH_2 PF13391.1 EGE00388.1 - 1.6e-10 40.5 0.0 4.2e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease zf-C3HC4 PF00097.20 EGE00390.1 - 5.2e-08 32.4 5.3 5.2e-08 32.4 3.7 4.6 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGE00390.1 - 3.5e-07 29.9 6.8 3.5e-07 29.9 4.7 3.4 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGE00390.1 - 9.8e-06 25.5 6.3 9.8e-06 25.5 4.3 4.4 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGE00390.1 - 2e-05 24.2 0.6 2e-05 24.2 0.4 2.6 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EGE00390.1 - 6.9e-05 22.6 6.8 6.9e-05 22.6 4.7 3.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING SH3_9 PF14604.1 EGE00390.1 - 0.0001 21.7 0.1 0.0001 21.7 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EGE00390.1 - 0.17 11.3 0.2 0.4 10.0 0.1 1.7 1 0 0 1 1 1 0 SH3 domain VGCC_beta4Aa_N PF12052.3 EGE00395.1 - 0.23 11.3 0.1 0.23 11.3 0.1 2.8 3 0 0 3 3 3 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF2510 PF10708.4 EGE00395.1 - 0.42 10.0 0.1 0.42 10.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) CytochromB561_N PF09786.4 EGE00395.1 - 9.8 4.4 12.2 12 4.2 8.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Peptidase_M28 PF04389.12 EGE00396.1 - 1.2e-20 73.9 0.1 1.7e-20 73.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M28 Mito_carr PF00153.22 EGE00397.1 - 9.4e-11 41.2 0.1 0.00049 19.7 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein PVL_ORF50 PF07768.6 EGE00398.1 - 0.042 13.8 0.5 0.059 13.3 0.3 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family SIN1 PF05422.7 EGE00399.1 - 9e-30 103.6 7.5 5.1e-18 64.8 0.0 3.0 3 0 0 3 3 3 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EGE00399.1 - 0.00095 19.0 0.1 0.0023 17.8 0.1 1.6 1 0 0 1 1 1 1 GLUT4 regulating protein TUG Pkinase PF00069.20 EGE00400.1 - 2.8e-70 236.4 0.0 4.7e-70 235.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE00400.1 - 8.7e-37 126.5 0.0 1.3e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE00400.1 - 8e-07 28.3 0.0 1.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGE00400.1 - 0.048 12.4 0.0 0.085 11.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EGE00400.1 - 0.18 11.1 1.5 0.28 10.5 0.0 1.9 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL DUF605 PF04652.11 EGE00400.1 - 0.35 10.2 24.8 0.46 9.8 17.2 1.1 1 0 0 1 1 1 0 Vta1 like APH PF01636.18 EGE00400.1 - 0.54 9.9 3.9 0.39 10.3 1.1 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family zf-Tim10_DDP PF02953.10 EGE00401.1 - 6.1e-22 76.6 3.3 8.2e-22 76.2 2.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Adeno_E1A PF02703.9 EGE00401.1 - 0.053 12.9 0.3 0.059 12.8 0.2 1.0 1 0 0 1 1 1 0 Early E1A protein Lectin_leg-like PF03388.8 EGE00402.1 - 1.6e-61 207.3 0.0 2.2e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EGE00402.1 - 0.015 14.6 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 0 Legume lectin domain BRF1 PF07741.8 EGE00403.1 - 0.063 13.5 17.0 0.054 13.7 7.0 3.0 2 1 0 2 2 2 0 Brf1-like TBP-binding domain PRCC PF10253.4 EGE00404.1 - 6.7e-43 147.5 1.8 6.7e-43 147.5 1.2 3.1 3 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting HNH_2 PF13391.1 EGE00405.1 - 7e-17 60.9 0.0 1.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease ATP-grasp_4 PF13535.1 EGE00406.1 - 3e-15 56.4 0.0 5.1e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGE00406.1 - 1.2e-08 35.0 0.0 1.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGE00406.1 - 0.00088 18.1 0.0 0.0053 15.5 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EGE00406.1 - 0.12 11.5 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain AAA_5 PF07728.9 EGE00407.1 - 4.8e-134 441.0 0.0 4.9e-24 84.6 0.0 10.2 10 0 0 10 10 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EGE00407.1 - 6.9e-31 107.1 0.1 0.00013 22.1 0.0 7.0 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EGE00407.1 - 7.5e-29 99.9 0.0 6.3e-10 38.7 0.0 7.4 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGE00407.1 - 5.4e-21 75.4 16.5 0.00017 21.6 0.1 8.5 8 0 0 8 8 6 6 AAA ATPase domain AAA_17 PF13207.1 EGE00407.1 - 2.1e-19 70.5 0.0 0.0058 17.4 0.0 7.3 6 0 0 6 6 6 3 AAA domain AAA_22 PF13401.1 EGE00407.1 - 5.7e-19 68.5 7.1 0.067 13.3 0.0 9.0 9 2 0 9 9 7 6 AAA domain Sigma54_activat PF00158.21 EGE00407.1 - 9.5e-19 67.4 0.0 0.017 14.5 0.0 6.6 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_33 PF13671.1 EGE00407.1 - 1.7e-18 66.8 0.0 0.03 14.1 0.0 7.5 6 2 0 6 6 6 4 AAA domain AAA_14 PF13173.1 EGE00407.1 - 3.5e-17 62.4 0.0 7.2e-05 22.7 0.0 8.1 8 0 0 8 8 7 2 AAA domain Sigma54_activ_2 PF14532.1 EGE00407.1 - 3.9e-16 59.3 0.6 0.0046 17.0 0.0 7.4 7 0 0 7 7 6 2 Sigma-54 interaction domain AAA_18 PF13238.1 EGE00407.1 - 4e-16 59.4 0.8 0.21 11.8 0.0 7.3 6 0 0 6 6 6 3 AAA domain Mg_chelatase PF01078.16 EGE00407.1 - 7.8e-15 54.5 2.6 0.62 9.1 0.0 9.1 8 1 1 9 9 9 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGE00407.1 - 2.6e-14 52.7 2.5 0.12 12.1 0.1 6.7 6 0 0 6 6 6 3 Part of AAA domain UPF0079 PF02367.12 EGE00407.1 - 3.1e-14 52.6 2.5 0.15 11.6 0.0 6.5 7 0 0 7 7 6 4 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EGE00407.1 - 4.2e-13 49.7 6.6 0.033 14.5 0.0 7.3 7 0 0 7 7 7 3 ABC transporter Zeta_toxin PF06414.7 EGE00407.1 - 5.2e-12 45.2 10.1 0.0053 15.8 0.0 7.7 9 0 0 9 9 7 3 Zeta toxin Miro PF08477.8 EGE00407.1 - 4e-11 43.4 1.2 0.83 10.1 0.0 6.7 6 0 0 6 6 6 1 Miro-like protein RNA_helicase PF00910.17 EGE00407.1 - 4.1e-11 43.0 0.2 1.2 9.3 0.0 6.7 6 0 0 6 6 6 1 RNA helicase RuvB_N PF05496.7 EGE00407.1 - 1.2e-10 40.8 2.8 0.24 10.4 0.0 6.1 6 0 0 6 6 6 3 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EGE00407.1 - 1.7e-10 40.8 9.2 0.15 11.7 0.1 7.2 7 0 0 7 7 6 2 NACHT domain AAA_29 PF13555.1 EGE00407.1 - 2.4e-10 39.7 0.5 0.2 11.2 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EGE00407.1 - 1.5e-09 37.5 0.4 0.65 9.3 0.0 5.8 6 0 0 6 6 5 2 AAA domain T2SE PF00437.15 EGE00407.1 - 1.5e-09 37.1 1.9 0.094 11.6 0.0 5.3 5 0 0 5 5 5 3 Type II/IV secretion system protein SRP54 PF00448.17 EGE00407.1 - 2.1e-09 37.0 1.2 0.99 8.8 0.0 5.9 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 EGE00407.1 - 3.3e-09 36.7 0.1 5.7 6.5 0.0 6.4 6 0 0 6 6 6 0 Archaeal ATPase PduV-EutP PF10662.4 EGE00407.1 - 6.2e-09 35.4 1.3 0.27 10.7 0.0 6.2 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EGE00407.1 - 8.1e-09 35.6 5.8 0.19 11.6 0.0 6.3 6 0 0 6 6 6 3 AAA domain IstB_IS21 PF01695.12 EGE00407.1 - 2.2e-08 33.6 0.1 2.6 7.4 0.0 6.2 6 0 0 6 6 6 2 IstB-like ATP binding protein DUF258 PF03193.11 EGE00407.1 - 4.9e-07 29.0 7.5 0.61 9.2 0.3 5.9 6 0 0 6 6 6 1 Protein of unknown function, DUF258 MobB PF03205.9 EGE00407.1 - 1.1e-06 28.3 1.5 10 5.8 0.0 6.6 7 0 0 7 7 6 0 Molybdopterin guanine dinucleotide synthesis protein B TIP49 PF06068.8 EGE00407.1 - 4.6e-06 25.5 2.7 0.84 8.2 0.0 5.0 5 0 0 5 5 5 1 TIP49 C-terminus AAA_7 PF12775.2 EGE00407.1 - 2.6e-05 23.4 0.8 3.6 6.6 0.0 5.1 5 0 0 5 5 5 0 P-loop containing dynein motor region D3 NTPase_1 PF03266.10 EGE00407.1 - 0.00013 21.7 4.3 1.3 8.6 0.0 5.2 6 0 0 6 6 4 1 NTPase Rad17 PF03215.10 EGE00407.1 - 0.00013 20.7 3.6 0.15 10.6 0.0 5.2 6 0 0 6 6 6 1 Rad17 cell cycle checkpoint protein CPT PF07931.7 EGE00407.1 - 0.0014 18.2 2.1 1.2 8.6 0.0 5.2 6 1 0 6 6 4 1 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 EGE00407.1 - 0.0015 17.7 0.1 11 5.0 0.0 4.6 4 0 0 4 4 4 0 KaiC MMR_HSR1 PF01926.18 EGE00407.1 - 0.0022 17.9 1.0 60 3.6 0.0 6.1 6 0 0 6 6 6 0 50S ribosome-binding GTPase PhoH PF02562.11 EGE00407.1 - 0.01 15.0 0.5 13 4.9 0.0 4.4 5 0 0 5 5 5 0 PhoH-like protein AAA_6 PF12774.2 EGE00407.1 - 0.011 15.2 0.0 40 3.6 0.0 5.7 6 1 0 6 6 6 0 Hydrolytic ATP binding site of dynein motor region D1 cobW PF02492.14 EGE00407.1 - 0.012 15.0 6.8 8 5.8 0.0 5.1 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 EGE00407.1 - 0.019 14.4 0.0 17 4.8 0.0 4.1 5 0 0 5 5 5 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 EGE00407.1 - 0.11 12.0 8.8 17 4.8 0.0 5.7 7 0 0 7 7 6 0 Conserved hypothetical ATP binding protein Ras PF00071.17 EGE00407.1 - 0.81 9.0 3.0 59 3.0 0.0 4.3 5 0 0 5 5 5 0 Ras family Voltage_CLC PF00654.15 EGE00408.1 - 6.6e-88 295.1 19.7 6.6e-88 295.1 13.7 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel Pox_L5 PF04872.8 EGE00409.1 - 0.057 13.0 0.1 0.15 11.6 0.1 1.7 1 1 0 1 1 1 0 Poxvirus L5 protein family Trypan_PARP PF05887.6 EGE00410.1 - 1e-05 25.3 17.9 1e-05 25.3 12.4 11.7 8 4 4 12 12 12 1 Procyclic acidic repetitive protein (PARP) HMG_box PF00505.14 EGE00411.1 - 2.6e-06 27.5 4.1 2.6e-06 27.5 2.8 2.6 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGE00411.1 - 3.1e-05 24.2 3.9 3.1e-05 24.2 2.7 2.8 3 0 0 3 3 3 1 HMG-box domain DUF4662 PF15578.1 EGE00411.1 - 0.0055 16.3 11.8 0.0074 15.8 2.8 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4662) DUF1074 PF06382.6 EGE00411.1 - 0.011 15.7 1.1 0.011 15.7 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1074) DEAD PF00270.24 EGE00412.1 - 6.2e-45 152.7 0.0 1.2e-44 151.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE00412.1 - 4.2e-24 84.2 0.0 1.2e-23 82.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGE00412.1 - 0.00035 19.4 0.0 0.0006 18.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGE00412.1 - 0.015 15.1 0.0 0.14 11.9 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit WLM PF08325.5 EGE00413.1 - 0.1 12.4 0.3 0.1 12.4 0.2 1.5 2 0 0 2 2 2 0 WLM domain zf-C2H2 PF00096.21 EGE00414.1 - 1.7e-16 59.4 59.3 1.8e-06 27.9 0.6 8.5 9 0 0 9 9 8 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE00414.1 - 9.9e-16 57.1 45.9 9.6e-08 31.9 0.6 7.4 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGE00414.1 - 5.8e-15 54.4 40.5 0.00029 20.9 0.6 7.5 7 0 0 7 7 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE00414.1 - 1.9e-12 46.9 6.4 0.003 17.6 0.3 5.7 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGE00414.1 - 9.6e-11 41.5 12.6 0.00023 21.2 0.3 5.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGE00414.1 - 1.6e-06 27.8 13.1 0.0098 15.7 0.6 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EGE00414.1 - 0.00023 20.7 11.0 0.087 12.5 0.2 4.7 4 0 0 4 4 4 2 zinc-finger of a C2HC-type BolA PF01722.13 EGE00414.1 - 0.017 15.1 0.8 0.4 10.6 0.0 3.0 2 1 1 3 3 3 0 BolA-like protein zf-Di19 PF05605.7 EGE00414.1 - 0.25 11.4 21.3 0.1 12.7 0.8 4.7 4 1 1 5 5 4 0 Drought induced 19 protein (Di19), zinc-binding EB_dh PF09459.5 EGE00414.1 - 0.31 10.4 2.6 3.1 7.1 0.3 2.2 2 0 0 2 2 2 0 Ethylbenzene dehydrogenase zf-H2C2_5 PF13909.1 EGE00414.1 - 7 7.1 33.0 1.4 9.2 0.4 7.7 7 0 0 7 7 7 0 C2H2-type zinc-finger domain DUF533 PF04391.7 EGE00415.1 - 0.15 11.4 1.2 0.27 10.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) zf-C2H2_4 PF13894.1 EGE00416.1 - 1e-07 31.7 10.4 2.4e-05 24.3 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGE00416.1 - 8.1e-06 25.8 3.1 8.1e-06 25.8 2.1 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGE00416.1 - 2.9e-05 24.1 3.4 2.9e-05 24.1 2.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 EGE00416.1 - 0.0017 18.4 1.0 0.0017 18.4 0.7 3.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type DUF2225 PF09986.4 EGE00416.1 - 0.015 14.7 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 EGE00416.1 - 0.029 14.4 1.3 0.029 14.4 0.9 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EGE00416.1 - 0.24 11.5 6.0 0.63 10.2 4.1 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EGE00416.1 - 0.34 10.8 3.0 0.31 11.0 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger SKG6 PF08693.5 EGE00420.1 - 0.045 13.0 1.7 0.086 12.1 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EGE00420.1 - 0.21 11.1 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family MGC-24 PF05283.6 EGE00420.1 - 2.6 7.8 10.1 0.41 10.4 4.2 1.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Herpes_capsid PF06112.6 EGE00420.1 - 7.2 6.6 11.7 32 4.5 8.1 2.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TPR_14 PF13428.1 EGE00421.1 - 2e-15 55.8 10.3 0.074 13.7 0.0 9.1 4 1 6 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGE00421.1 - 1.3e-12 47.8 1.1 0.0044 17.3 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGE00421.1 - 9.4e-11 42.0 7.7 0.11 13.1 0.0 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat HAT PF02184.11 EGE00421.1 - 7.8e-07 28.7 56.9 6.7e-05 22.5 1.2 10.7 11 0 0 11 11 11 4 HAT (Half-A-TPR) repeat TPR_17 PF13431.1 EGE00421.1 - 9.2e-05 22.3 0.2 1.3 9.4 0.0 5.0 7 0 0 7 7 4 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EGE00421.1 - 9.5e-05 22.0 26.7 0.0093 15.7 1.7 6.0 4 2 1 5 5 5 3 U3 small nucleolar RNA-associated protein 6 Apc3 PF12895.2 EGE00421.1 - 0.0011 19.0 0.7 0.045 13.8 0.1 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGE00421.1 - 0.0084 16.0 18.1 0.094 12.6 0.7 6.6 5 3 4 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGE00421.1 - 0.027 14.2 13.0 7.7 6.5 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGE00421.1 - 0.1 12.5 15.8 0.75 9.8 0.0 6.7 9 0 0 9 9 9 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EGE00421.1 - 0.32 9.8 33.6 0.41 9.4 5.3 5.3 2 2 2 4 4 4 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.1 EGE00421.1 - 0.68 10.5 17.3 14 6.4 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGE00421.1 - 2.7 7.9 9.1 3 7.7 0.3 4.3 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Prp31_C PF09785.4 EGE00422.1 - 1e-45 155.1 0.7 2e-45 154.2 0.5 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EGE00422.1 - 2.3e-40 137.3 0.0 5e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGE00422.1 - 1.3e-21 76.0 0.1 2.5e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain eIF-3c_N PF05470.7 EGE00422.1 - 0.027 12.5 0.7 0.039 12.0 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AdoHcyase PF05221.12 EGE00423.1 - 2.1e-136 453.1 0.1 2.4e-136 452.9 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EGE00423.1 - 8.1e-85 282.6 2.2 1.7e-84 281.6 1.5 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EGE00423.1 - 2.9e-07 29.8 0.1 5.7e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EGE00423.1 - 0.00013 21.3 0.2 0.00024 20.5 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EGE00423.1 - 0.00086 19.2 0.2 0.002 18.0 0.1 1.7 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EGE00423.1 - 0.016 14.7 0.1 0.029 13.9 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM107 PF14995.1 EGE00423.1 - 0.094 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF3759 PF12585.3 EGE00424.1 - 1.7e-39 133.6 8.5 1.9e-39 133.4 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Phe_ZIP PF08916.6 EGE00424.1 - 0.14 12.5 0.4 0.14 12.5 0.2 1.7 2 0 0 2 2 2 0 Phenylalanine zipper Band_7 PF01145.20 EGE00426.1 - 2.9e-30 105.4 0.7 2.9e-30 105.4 0.5 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family RecX PF02631.11 EGE00426.1 - 0.0087 16.2 1.6 0.023 14.9 0.4 2.1 1 1 1 2 2 2 1 RecX family Band_7_1 PF13421.1 EGE00426.1 - 0.022 14.2 0.0 0.054 13.0 0.0 1.6 1 1 0 1 1 1 0 SPFH domain-Band 7 family Mod_r PF07200.8 EGE00430.1 - 1.2e-12 48.0 1.4 1.5e-12 47.6 1.0 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein PAP2 PF01569.16 EGE00431.1 - 2.5e-22 78.9 0.7 7.2e-22 77.4 0.5 1.7 1 0 0 1 1 1 1 PAP2 superfamily DUF2370 PF10176.4 EGE00431.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF1233 PF06806.7 EGE00433.1 - 0.1 12.1 2.3 1 8.9 0.0 2.3 1 1 0 2 2 2 0 Putative excisionase (DUF1233) Cupin_2 PF07883.6 EGE00433.1 - 0.12 11.9 0.2 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Cupin domain Aldo_ket_red PF00248.16 EGE00434.1 - 3.9e-56 189.9 0.1 4.5e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.9 EGE00435.1 - 5.2e-12 45.5 0.3 7.8e-12 44.9 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.8 EGE00436.1 - 0.00019 21.2 0.4 0.00031 20.5 0.3 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EGE00436.1 - 0.037 14.0 1.6 0.13 12.3 1.2 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 EGE00436.1 - 0.096 12.7 1.9 1.6 8.8 0.1 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) NPR3 PF03666.8 EGE00437.1 - 3.6e-141 470.8 0.1 1.5e-139 465.4 0.0 2.1 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 EGE00437.1 - 0.0017 17.1 0.0 0.0038 16.0 0.0 1.5 1 0 0 1 1 1 1 Nitrogen permease regulator 2 La PF05383.12 EGE00438.1 - 1e-18 66.8 0.2 1.8e-18 66.0 0.2 1.4 1 0 0 1 1 1 1 La domain Ank_5 PF13857.1 EGE00439.1 - 5.8e-15 54.9 0.4 7.4e-12 45.1 0.3 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGE00439.1 - 6.5e-13 48.8 2.2 9.9e-07 29.0 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE00439.1 - 2.7e-11 43.6 0.1 1.5e-08 34.8 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EGE00439.1 - 8.4e-07 28.5 0.2 7.9e-05 22.2 0.1 3.0 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EGE00439.1 - 1.2e-06 28.1 0.1 0.001 19.0 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat YejG PF13989.1 EGE00439.1 - 0.03 14.4 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 YejG-like protein RNA_lig_T4_1 PF09511.5 EGE00440.1 - 1.1e-74 250.6 0.2 9.7e-73 244.2 0.0 2.9 3 0 0 3 3 3 1 RNA ligase tRNA_lig_CPD PF08302.6 EGE00440.1 - 2.1e-52 177.9 8.8 7.8e-52 176.0 3.8 2.2 1 1 1 2 2 2 2 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 EGE00440.1 - 6.3e-47 159.5 0.3 1.8e-46 158.0 0.1 1.9 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_17 PF13207.1 EGE00440.1 - 0.044 14.5 0.0 0.16 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGE00440.1 - 0.047 13.9 3.0 0.11 12.7 2.1 1.6 1 1 0 1 1 1 0 AAA domain DNase-RNase PF02577.9 EGE00440.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Bifunctional nuclease AAA PF00004.24 EGE00443.1 - 1.2e-40 138.7 0.0 3.2e-40 137.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGE00443.1 - 0.00012 21.2 0.0 0.00052 19.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGE00443.1 - 0.0002 21.4 1.5 0.0081 16.1 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EGE00443.1 - 0.0003 20.5 2.0 0.00079 19.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGE00443.1 - 0.0018 18.2 2.3 0.0049 16.7 0.0 2.8 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EGE00443.1 - 0.002 17.0 1.6 0.03 13.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EGE00443.1 - 0.0025 17.0 1.6 0.041 13.1 0.1 2.7 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.1 EGE00443.1 - 0.0031 17.6 3.6 0.022 14.9 0.0 3.1 3 1 0 4 4 3 1 AAA domain Mg_chelatase PF01078.16 EGE00443.1 - 0.0065 15.6 0.1 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EGE00443.1 - 0.0085 15.9 0.0 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGE00443.1 - 0.013 15.2 0.3 0.032 13.9 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EGE00443.1 - 0.019 14.3 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EGE00443.1 - 0.036 13.4 1.3 0.44 9.9 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EGE00443.1 - 0.16 12.7 0.1 0.16 12.7 0.1 3.2 2 2 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.12 EGE00443.1 - 0.42 9.4 2.2 4.7 6.0 0.1 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EGE00443.1 - 0.43 10.1 5.9 0.51 9.8 0.0 2.7 2 2 0 3 3 2 0 AAA domain TauD PF02668.11 EGE00444.1 - 2.6e-37 128.9 0.0 3.6e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EGE00444.1 - 2.7e-06 27.7 0.0 4.2e-05 23.8 0.0 1.8 1 1 1 2 2 2 2 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 EGE00444.1 - 0.029 14.8 0.1 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DM PF00751.13 EGE00444.1 - 0.036 13.5 1.2 0.06 12.8 0.2 1.8 2 0 0 2 2 2 0 DM DNA binding domain CsiD PF08943.5 EGE00444.1 - 0.04 12.8 0.0 0.37 9.6 0.0 2.0 1 1 0 1 1 1 0 CsiD MaoC_dehydratas PF01575.14 EGE00445.1 - 2.4e-23 81.8 0.0 1.3e-22 79.4 0.0 2.0 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EGE00445.1 - 7.2e-11 42.0 0.0 1.1e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Methyltransf_31 PF13847.1 EGE00446.1 - 2.1e-12 46.8 0.0 3.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGE00446.1 - 6.4e-11 41.9 0.0 9.8e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EGE00446.1 - 3.7e-10 40.3 0.0 8.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE00446.1 - 2.8e-09 37.0 0.0 6.5e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE00446.1 - 2.3e-07 31.1 0.0 5.5e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EGE00446.1 - 3.9e-07 29.3 0.0 1e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 EGE00446.1 - 3.8e-06 26.7 0.0 8.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGE00446.1 - 4e-06 25.7 0.0 5.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EGE00446.1 - 1.4e-05 25.3 0.0 5.1e-05 23.5 0.0 2.0 3 0 0 3 3 1 1 Methyltransferase domain MTS PF05175.9 EGE00446.1 - 1.6e-05 24.3 0.0 2.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EGE00446.1 - 1.8e-05 24.0 0.0 2.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EGE00446.1 - 0.0003 21.2 0.0 0.0006 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGE00446.1 - 0.0007 19.6 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EGE00446.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EGE00446.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EGE00446.1 - 0.022 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EGE00446.1 - 0.027 13.9 0.2 0.046 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 EGE00446.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EGE00446.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.12 EGE00446.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF2007 PF09413.5 EGE00447.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) Per1 PF04080.8 EGE00448.1 - 1.9e-106 355.3 12.2 2.5e-106 355.0 8.5 1.1 1 0 0 1 1 1 1 Per1-like Orai-1 PF07856.7 EGE00448.1 - 0.22 11.0 5.5 0.14 11.6 2.4 1.6 2 0 0 2 2 2 0 Mediator of CRAC channel activity PGM_PMM_I PF02878.11 EGE00449.1 - 1.4e-18 66.6 0.7 3.7e-08 32.9 0.0 3.2 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EGE00449.1 - 1.2e-15 57.6 0.4 7.6e-15 55.1 0.1 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGE00449.1 - 1.3e-09 37.8 0.2 4.6e-09 36.1 0.1 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EGE00449.1 - 0.00061 19.8 0.4 0.0023 17.9 0.3 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DEAD PF00270.24 EGE00450.1 - 5.2e-47 159.4 0.0 8.3e-47 158.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE00450.1 - 6.2e-26 90.0 0.0 1.3e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE00450.1 - 0.00068 19.5 0.0 0.002 17.9 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGE00450.1 - 0.049 13.3 0.3 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Brix PF04427.13 EGE00451.1 - 8.4e-57 191.9 0.4 1.1e-56 191.4 0.3 1.2 1 0 0 1 1 1 1 Brix domain Lum_binding PF00677.12 EGE00452.1 - 3.8e-37 126.0 0.0 9.9e-22 76.6 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain Lumazine_bd_2 PF12893.2 EGE00452.1 - 0.032 14.7 0.0 0.077 13.5 0.0 1.6 1 1 0 1 1 1 0 Putative lumazine-binding CoA_transf_3 PF02515.12 EGE00453.1 - 3e-60 202.7 0.0 5.2e-60 201.9 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.24 EGE00454.1 - 1.2e-06 28.1 9.3 2.2e-06 27.2 6.5 1.5 1 0 0 1 1 1 1 PHD-finger FYVE_2 PF02318.11 EGE00454.1 - 0.15 11.9 2.0 0.27 11.1 1.4 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_1 PF14446.1 EGE00454.1 - 0.2 11.3 6.1 0.46 10.2 4.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EGE00454.1 - 3.6 6.9 10.4 0.81 9.0 3.8 2.4 2 1 0 2 2 2 0 PHD-finger Band_7 PF01145.20 EGE00455.1 - 2.3e-26 92.7 2.1 3.9e-26 92.0 1.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Dak1_2 PF13684.1 EGE00455.1 - 0.015 14.2 1.6 0.023 13.6 1.1 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family UPF0149 PF03695.8 EGE00455.1 - 0.044 13.6 0.2 0.89 9.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) CBFNT PF08143.6 EGE00455.1 - 2 9.5 10.1 7.6 7.7 0.5 2.4 2 0 0 2 2 2 0 CBFNT (NUC161) domain Ribosomal_L27e PF01777.13 EGE00457.1 - 7.1e-38 128.6 3.5 8.9e-38 128.2 2.4 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EGE00457.1 - 0.0011 18.5 0.3 0.0011 18.5 0.2 2.0 2 1 0 2 2 2 1 KOW motif SMAP PF15477.1 EGE00457.1 - 0.11 12.8 2.2 0.27 11.5 1.5 1.6 1 1 0 1 1 1 0 Small acidic protein family LPP PF04728.8 EGE00458.1 - 9.6e-17 60.5 4.5 0.14 12.0 0.0 8.9 7 1 1 8 8 8 6 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 EGE00458.1 - 0.0013 17.9 39.8 0.013 14.7 0.0 8.5 8 2 3 11 11 11 5 Reovirus sigma C capsid protein Ish1 PF10281.4 EGE00458.1 - 0.022 14.8 0.4 25 5.0 0.0 5.5 6 0 0 6 6 6 0 Putative stress-responsive nuclear envelope protein DUF948 PF06103.6 EGE00458.1 - 0.56 10.1 0.0 0.56 10.1 0.0 13.4 12 4 6 18 18 18 0 Bacterial protein of unknown function (DUF948) Tweety PF04906.8 EGE00458.1 - 2.9 6.1 3.7 34 2.6 1.2 3.8 3 0 0 3 3 3 0 Tweety SWIB PF02201.13 EGE00459.1 - 0.032 13.9 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain DUF4410 PF14366.1 EGE00459.1 - 0.053 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) HXXSHH PF07586.6 EGE00459.1 - 0.067 12.1 0.2 9.5 5.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) PCI PF01399.22 EGE00460.1 - 8.9e-20 70.9 0.1 1.8e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 PCI domain DDRGK PF09756.4 EGE00460.1 - 6.9e-05 22.3 0.1 0.00012 21.5 0.1 1.3 1 0 0 1 1 1 1 DDRGK domain TPR_8 PF13181.1 EGE00460.1 - 0.00055 19.5 0.4 13 5.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGE00460.1 - 0.0053 16.5 0.8 28 4.9 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGE00460.1 - 0.013 15.0 0.2 2.7 7.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EGE00460.1 - 0.047 13.4 0.1 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 AAA_22 PF13401.1 EGE00460.1 - 0.11 12.6 0.9 0.37 10.9 0.1 2.3 2 1 0 2 2 2 0 AAA domain TPR_12 PF13424.1 EGE00460.1 - 0.11 12.4 9.0 4.2 7.3 0.2 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Sof1 PF04158.9 EGE00461.1 - 6.8e-30 102.9 13.1 8.2e-30 102.6 9.1 1.1 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.27 EGE00461.1 - 0.00025 20.8 0.0 0.00043 20.0 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat adh_short PF00106.20 EGE00462.1 - 6.6e-23 81.4 0.3 1.1e-22 80.7 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE00462.1 - 1.5e-15 57.5 0.0 2.8e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE00462.1 - 1.5e-06 28.0 0.1 3.6e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 KR domain DUF2306 PF10067.4 EGE00463.1 - 0.025 14.6 1.4 0.025 14.6 0.9 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) Zn_clus PF00172.13 EGE00464.1 - 6.4e-08 32.3 9.5 1.5e-07 31.2 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase_2 PF12681.2 EGE00465.1 - 7e-14 52.3 0.0 1e-13 51.8 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGE00465.1 - 1.5e-06 28.1 0.0 2.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PUF PF00806.14 EGE00466.1 - 4.8e-12 44.6 0.0 0.28 10.7 0.0 7.3 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat Pyridoxal_deC PF00282.14 EGE00467.1 - 1.4e-76 257.3 0.0 1.7e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EGE00467.1 - 2e-07 30.4 0.0 2.7e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGE00467.1 - 2.4e-07 29.8 0.0 3.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 EGE00467.1 - 0.023 13.1 0.0 0.04 12.4 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) RINT1_TIP1 PF04437.8 EGE00468.1 - 2e-163 544.4 1.2 3.2e-163 543.8 0.0 1.8 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Nup54 PF13874.1 EGE00468.1 - 0.057 13.0 5.4 0.15 11.7 3.7 1.8 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ALMT PF11744.3 EGE00468.1 - 0.78 8.3 2.6 1.2 7.7 1.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.14 EGE00468.1 - 7.2 4.3 5.9 10 3.8 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DNA_ligase_A_M PF01068.16 EGE00469.1 - 2.1e-48 164.4 0.0 9.8e-46 155.6 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGE00469.1 - 1.3e-41 142.3 0.0 2.2e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGE00469.1 - 4.7e-19 68.5 0.1 2.4e-18 66.3 0.0 2.3 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region Peptidase_C36 PF05415.6 EGE00469.1 - 0.017 14.9 0.0 0.057 13.3 0.0 1.8 2 0 0 2 2 2 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase YukD PF08817.5 EGE00469.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DJ-1_PfpI PF01965.19 EGE00470.1 - 3.3e-20 72.0 0.4 9.3e-20 70.5 0.3 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EGE00470.1 - 8.4e-05 22.0 0.1 0.0007 19.0 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family GST_N_3 PF13417.1 EGE00471.1 - 2.1e-09 37.4 0.1 4.3e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE00471.1 - 2.4e-08 33.8 0.0 5.6e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGE00471.1 - 7.9e-07 28.8 2.9 1.5e-06 28.0 1.3 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGE00471.1 - 0.00036 20.6 0.0 0.00083 19.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGE00471.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GluR_Homer-bdg PF10606.4 EGE00472.1 - 0.017 15.0 1.5 0.017 15.0 1.0 2.2 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor TFIIA PF03153.8 EGE00472.1 - 2.7 7.7 5.1 3.4 7.4 3.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Metallopep PF12044.3 EGE00473.1 - 1.6e-127 425.5 0.0 9.5e-64 215.3 0.2 2.1 1 1 1 2 2 2 2 Putative peptidase family Retinal PF15449.1 EGE00475.1 - 0.14 9.7 6.1 0.14 9.8 4.2 1.0 1 0 0 1 1 1 0 Retinal protein RXT2_N PF08595.6 EGE00477.1 - 0.0003 20.6 0.4 0.00037 20.3 0.3 1.1 1 0 0 1 1 1 1 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EGE00477.1 - 0.0017 17.8 3.3 0.0018 17.7 2.3 1.2 1 0 0 1 1 1 1 Nucleoplasmin Cwf_Cwc_15 PF04889.7 EGE00477.1 - 0.17 11.5 2.6 0.17 11.5 1.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 EGE00477.1 - 0.32 10.2 3.2 0.36 10.0 2.2 1.1 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 EGE00477.1 - 0.55 9.8 4.4 0.69 9.4 3.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.1 EGE00477.1 - 0.97 9.6 6.7 1.6 8.9 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 EGE00477.1 - 1.2 9.4 11.0 0.38 11.0 5.7 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sod_Cu PF00080.15 EGE00478.1 - 0.037 14.1 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) CDP-OH_P_transf PF01066.16 EGE00479.1 - 1.6e-18 66.8 4.1 3.2e-18 65.9 2.8 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase MBOAT PF03062.14 EGE00480.1 - 3.1e-47 161.2 4.9 6.7e-47 160.1 3.4 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Herpes_UL56 PF04534.7 EGE00480.1 - 0.05 13.3 0.4 0.05 13.3 0.3 1.5 2 0 0 2 2 2 0 Herpesvirus UL56 protein Abi PF02517.11 EGE00482.1 - 8.4e-13 48.2 10.1 8.4e-13 48.2 7.0 2.4 2 1 0 2 2 2 1 CAAX protease self-immunity DUF1358 PF07096.6 EGE00482.1 - 0.12 12.0 0.5 0.31 10.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) Suc_Fer-like PF06999.7 EGE00483.1 - 8.5e-46 156.8 0.0 1e-45 156.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF2531 PF10748.4 EGE00483.1 - 0.0038 16.4 0.0 0.0061 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2531) zf-C2H2_2 PF12756.2 EGE00484.1 - 4.4e-19 68.4 7.7 2.6e-18 66.0 3.7 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EGE00484.1 - 0.0072 16.4 0.0 0.029 14.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGE00484.1 - 0.077 13.1 0.4 0.74 10.0 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Fer4 PF00037.22 EGE00484.1 - 0.4 10.3 0.1 0.4 10.3 0.1 2.5 3 0 0 3 3 3 0 4Fe-4S binding domain tRNA-synt_1 PF00133.17 EGE00485.1 - 2.1e-51 174.6 0.0 5.6e-36 123.7 0.0 5.0 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EGE00485.1 - 8.6e-38 129.4 0.0 1.3e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EGE00485.1 - 2.1e-28 99.1 0.1 1.2e-25 90.0 0.0 3.2 2 1 0 2 2 2 1 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGE00485.1 - 2.6e-14 53.2 0.0 4.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGE00485.1 - 0.00022 20.4 0.0 0.00057 19.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EGE00485.1 - 0.0023 16.8 0.0 0.0055 15.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 EGE00485.1 - 0.035 12.7 0.1 6.3 5.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Cation_ATPase_C PF00689.16 EGE00486.1 - 0.02 14.4 6.3 0.035 13.6 4.3 1.4 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DsbD_2 PF13386.1 EGE00486.1 - 0.97 9.1 7.6 0.19 11.4 1.5 2.1 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region DUF2754 PF10953.3 EGE00486.1 - 5.4 7.1 7.2 3 7.9 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2754) 2-Hacid_dh_C PF02826.14 EGE00487.1 - 2.9e-49 166.6 0.0 4.3e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGE00487.1 - 5e-16 58.3 0.0 7.4e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGE00487.1 - 0.0057 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase FH2 PF02181.18 EGE00489.1 - 2e-81 273.7 5.9 2e-81 273.7 4.1 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EGE00489.1 - 3.8e-69 231.8 0.5 1.3e-68 230.1 0.0 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EGE00489.1 - 4.9e-50 169.6 2.7 1.7e-48 164.6 0.6 2.6 1 1 1 2 2 2 2 Diaphanous FH3 Domain DUF3886 PF13025.1 EGE00491.1 - 0.14 12.1 0.2 0.14 12.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) TrmE_N PF10396.4 EGE00492.1 - 1.2e-35 121.9 0.0 2.5e-35 120.8 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EGE00492.1 - 3.5e-21 75.3 0.2 2.1e-20 72.9 0.0 2.4 2 1 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EGE00492.1 - 1.4e-16 60.4 0.0 2.8e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGE00492.1 - 6.7e-06 26.0 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.13 EGE00492.1 - 2.5e-05 23.6 0.3 0.00018 20.8 0.2 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGE00492.1 - 6.9e-05 22.3 0.0 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGE00492.1 - 0.0011 19.4 0.0 0.0028 18.1 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein Glyco_hydro_3_C PF01915.17 EGE00492.1 - 0.026 14.0 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain ABC_tran PF00005.22 EGE00492.1 - 0.043 14.1 0.1 0.14 12.4 0.1 1.8 1 1 0 1 1 1 0 ABC transporter MCM PF00493.18 EGE00492.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family AAA_28 PF13521.1 EGE00492.1 - 0.11 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_pol_L_2 PF13656.1 EGE00493.1 - 8.3e-31 105.2 0.0 1.1e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EGE00493.1 - 1.2e-12 46.7 0.0 1.7e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SDA1 PF05285.7 EGE00493.1 - 0.086 12.1 1.3 0.079 12.2 0.9 1.1 1 0 0 1 1 1 0 SDA1 Complex1_LYR_2 PF13233.1 EGE00494.1 - 3.3e-07 30.7 0.3 4.3e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGE00494.1 - 6.8e-06 25.7 0.3 1.6e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGE00494.1 - 1.2e-05 25.4 0.5 1.7e-05 24.9 0.4 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Abhydrolase_6 PF12697.2 EGE00496.1 - 2.3e-15 57.1 0.0 3.5e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE00496.1 - 4.5e-10 39.4 0.0 7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE00496.1 - 1.7e-08 34.3 0.0 4.3e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EGE00496.1 - 0.0088 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) TRAPPC9-Trs120 PF08626.6 EGE00497.1 - 3.2e-139 465.3 0.0 1.2e-138 463.4 0.0 1.9 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit CARDB PF07705.6 EGE00497.1 - 0.0071 16.3 0.0 6.6 6.8 0.0 3.3 3 0 0 3 3 3 2 CARDB DUF3684 PF12449.3 EGE00498.1 - 0 1497.5 0.0 0 1497.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EGE00498.1 - 8.5e-06 25.4 0.0 2.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGE00498.1 - 0.0036 17.0 0.0 0.0088 15.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.5 EGE00498.1 - 2.3 8.0 9.1 0.23 11.3 0.1 3.0 3 0 0 3 3 3 0 WLM domain Pro-kuma_activ PF09286.6 EGE00499.1 - 1.6e-37 128.7 0.2 3e-37 127.8 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGE00499.1 - 4.6e-09 35.8 0.0 7.8e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Subtilase family DUF1122 PF06557.6 EGE00500.1 - 0.02 14.0 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) BTB PF00651.26 EGE00501.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain RdRP PF05183.7 EGE00502.1 - 1.9e-162 541.9 0.0 2.6e-162 541.5 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Med6 PF04934.9 EGE00503.1 - 1.4e-42 144.5 0.0 3.4e-42 143.3 0.0 1.6 2 0 0 2 2 2 1 MED6 mediator sub complex component Lysine_decarbox PF03641.9 EGE00504.1 - 1.3e-20 73.5 0.2 2.3e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase Proteasome PF00227.21 EGE00505.1 - 1.1e-48 165.0 0.2 1.6e-48 164.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGE00505.1 - 8.5e-12 44.1 1.1 1.3e-11 43.5 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Vps55 PF04133.9 EGE00506.1 - 2.2e-45 153.2 7.3 2.5e-45 153.1 5.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2798 PF11391.3 EGE00506.1 - 0.31 10.8 0.1 0.31 10.8 0.1 3.1 3 2 1 4 4 4 0 Protein of unknown function (DUF2798) UPF0220 PF05255.6 EGE00508.1 - 5.5e-66 220.9 3.1 6.2e-66 220.7 2.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) HEAT_EZ PF13513.1 EGE00509.1 - 1.3e-05 25.5 0.0 2.4e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 HEAT-like repeat HEAT_2 PF13646.1 EGE00509.1 - 0.0001 22.5 0.1 0.00011 22.3 0.1 1.4 1 1 0 1 1 1 1 HEAT repeats RICTOR_V PF14668.1 EGE00509.1 - 0.0031 17.4 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.17 EGE00509.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 HEAT repeat Arm PF00514.18 EGE00509.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Apc5 PF12862.2 EGE00509.1 - 0.047 13.5 0.1 3.6 7.4 0.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 Actin PF00022.14 EGE00510.1 - 1.3e-111 372.8 0.0 1.5e-111 372.6 0.0 1.0 1 0 0 1 1 1 1 Actin Glyco_hydro_18 PF00704.23 EGE00511.1 - 7.9e-66 222.8 10.3 5.3e-48 164.2 1.7 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 AIRS_C PF02769.17 EGE00512.1 - 9e-34 116.6 0.2 2.6e-33 115.2 0.0 1.8 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EGE00512.1 - 1.2e-27 95.9 0.4 2.4e-27 94.9 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain GARS_A PF01071.14 EGE00512.1 - 5.6e-21 74.9 0.0 1e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS PF00586.19 EGE00512.1 - 1e-16 60.9 1.4 4.6e-16 58.8 1.0 2.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PCI PF01399.22 EGE00513.1 - 3.2e-22 78.8 0.0 1.2e-21 77.0 0.0 2.0 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 EGE00513.1 - 0.011 15.1 0.3 0.16 11.2 0.0 2.4 2 0 0 2 2 2 0 Putative aspartate racemase DASH_Dad3 PF08656.5 EGE00513.1 - 0.073 12.7 2.9 0.061 13.0 0.5 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 CLTH PF10607.4 EGE00513.1 - 0.085 12.5 2.9 1.6 8.3 1.7 2.7 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain FSH1 PF03959.8 EGE00514.1 - 5.3e-67 225.3 0.0 7.4e-67 224.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EGE00514.1 - 1.5e-09 38.1 0.0 2.6e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE00514.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EGE00514.1 - 0.0016 17.7 0.0 0.056 12.7 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EGE00514.1 - 0.043 13.2 0.1 8.1 5.8 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 EGE00514.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.4 EGE00514.1 - 0.13 11.4 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Acyltransferase PF01553.16 EGE00515.1 - 0.038 13.4 0.0 0.072 12.5 0.0 1.4 1 1 0 1 1 1 0 Acyltransferase Nop10p PF04135.7 EGE00516.1 - 0.081 12.6 0.2 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family Ribosomal_S27e PF01667.12 EGE00518.1 - 5.9e-29 99.3 6.6 7.4e-29 99.0 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EGE00518.1 - 0.0082 16.0 1.3 0.0093 15.8 0.9 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 EGE00518.1 - 0.12 11.9 0.7 0.22 11.0 0.5 1.5 1 0 0 1 1 1 0 CSL zinc finger CDP-OH_P_transf PF01066.16 EGE00520.1 - 1.9e-16 60.2 3.2 1.9e-16 60.2 2.2 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase 2TM PF13239.1 EGE00520.1 - 6.3 6.9 6.9 1.8 8.6 0.2 2.9 3 0 0 3 3 3 0 2TM domain NIPSNAP PF07978.8 EGE00521.1 - 2.6e-39 133.2 0.4 9e-29 99.4 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP Pyridox_oxidase PF01243.15 EGE00522.1 - 4e-12 45.9 0.0 7.9e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_C65 PF10275.4 EGE00523.1 - 7.2e-39 133.5 0.3 1.1e-38 133.0 0.2 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain DNA_ligase_IV PF11411.3 EGE00523.1 - 0.15 11.7 1.0 6.7 6.5 0.0 2.4 2 0 0 2 2 2 0 DNA ligase IV PCI PF01399.22 EGE00525.1 - 2.4e-16 59.9 0.6 5.5e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EGE00525.1 - 5.4e-07 29.4 0.1 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 EGE00525.1 - 0.00027 20.5 1.1 0.037 13.8 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGE00525.1 - 0.005 16.6 3.5 0.077 12.9 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGE00525.1 - 0.0085 16.0 3.8 0.053 13.4 0.1 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 EGE00525.1 - 0.0085 15.9 0.1 0.03 14.1 0.1 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EGE00525.1 - 0.0089 15.9 0.1 2.4 8.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat CorA PF01544.13 EGE00525.1 - 0.033 13.2 0.6 0.069 12.1 0.4 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ipi1_N PF12333.3 EGE00525.1 - 0.059 13.3 0.1 3 7.8 0.0 2.4 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TPR_1 PF00515.23 EGE00525.1 - 0.082 12.5 3.5 0.26 10.9 0.1 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGE00525.1 - 0.15 12.7 0.6 3.4 8.5 0.0 3.2 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGE00525.1 - 0.16 11.6 2.1 0.5 10.0 0.1 3.0 3 1 0 3 3 3 0 TPR repeat TPR_8 PF13181.1 EGE00525.1 - 0.29 11.0 0.1 0.29 11.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CWC25 PF12542.3 EGE00526.1 - 2.3e-26 92.0 0.8 2.3e-26 92.0 0.5 3.8 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EGE00526.1 - 2.8e-13 49.6 10.4 2.8e-13 49.6 7.2 3.9 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3674 PF12426.3 EGE00526.1 - 0.13 11.6 0.6 0.46 9.9 0.1 2.1 2 0 0 2 2 2 0 RNA dependent RNA polymerase DUF605 PF04652.11 EGE00526.1 - 0.55 9.5 14.8 0.76 9.1 10.2 1.4 1 0 0 1 1 1 0 Vta1 like Ras PF00071.17 EGE00527.1 - 7.7e-53 178.1 0.0 9e-53 177.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE00527.1 - 5e-16 59.2 0.0 6.8e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE00527.1 - 7.2e-11 41.6 0.0 1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGE00527.1 - 1.9e-05 23.9 0.0 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGE00527.1 - 0.00099 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGE00527.1 - 0.0064 15.2 0.0 0.0093 14.6 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EGE00527.1 - 0.018 14.9 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EGE00527.1 - 0.04 13.6 0.0 0.051 13.2 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EGE00527.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter BPL_LplA_LipB PF03099.14 EGE00528.1 - 4.4e-09 36.4 0.0 7.3e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family F-box PF00646.28 EGE00529.1 - 0.0034 17.0 2.7 0.19 11.4 0.1 3.4 3 0 0 3 3 3 2 F-box domain DUF3387 PF11867.3 EGE00529.1 - 0.12 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Ank PF00023.25 EGE00530.1 - 1.3e-20 72.0 0.0 1.1e-07 31.2 0.1 3.6 3 1 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EGE00530.1 - 7.8e-18 64.6 0.3 1e-08 35.3 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE00530.1 - 7.3e-16 58.2 2.4 4.1e-06 27.1 0.0 3.0 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE00530.1 - 7.6e-11 41.1 0.6 0.0021 18.1 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGE00530.1 - 1.2e-10 41.2 3.7 0.00022 21.3 0.3 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) polyprenyl_synt PF00348.12 EGE00531.1 - 2.2e-46 157.8 0.0 2.8e-43 147.6 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase Rpn3_C PF08375.6 EGE00532.1 - 2.3e-24 85.5 0.3 2.3e-24 85.5 0.2 2.5 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EGE00532.1 - 3.5e-21 75.5 0.1 1.9e-20 73.1 0.0 2.2 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EGE00532.1 - 0.018 14.8 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 DASH_Spc34 PF08657.5 EGE00533.1 - 1.3e-57 195.4 9.2 2.1e-33 116.0 3.4 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DUF848 PF05852.6 EGE00533.1 - 8.4e-05 22.4 3.2 0.00016 21.5 2.2 1.4 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) IncA PF04156.9 EGE00533.1 - 0.00015 21.4 1.1 0.00021 20.9 0.7 1.2 1 0 0 1 1 1 1 IncA protein ISG65-75 PF11727.3 EGE00533.1 - 0.0092 15.0 1.3 0.012 14.6 0.9 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein Prefoldin_2 PF01920.15 EGE00533.1 - 0.026 14.2 6.8 0.54 10.0 0.6 2.5 2 0 0 2 2 2 0 Prefoldin subunit MIF4G_like_2 PF09090.6 EGE00533.1 - 0.08 12.1 0.7 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 MIF4G like DASH_Spc19 PF08287.6 EGE00533.1 - 0.093 12.3 2.8 0.17 11.5 2.0 1.4 1 0 0 1 1 1 0 Spc19 DUF1136 PF06582.7 EGE00533.1 - 1.3 8.8 4.3 1.2 8.8 1.2 2.4 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) F-box PF00646.28 EGE00534.1 - 8.8e-05 22.0 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGE00534.1 - 0.0046 16.6 0.0 0.014 15.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like TFIID_20kDa PF03847.8 EGE00535.1 - 1.1e-23 83.3 0.0 1.9e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CorA PF01544.13 EGE00536.1 - 2.3e-17 62.9 1.5 4.3e-17 62.0 1.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1203 PF06718.6 EGE00537.1 - 3.2e-24 84.9 0.0 3.8e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1203) eIF2A PF08662.6 EGE00539.1 - 3e-84 281.5 0.1 5.3e-83 277.5 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EGE00539.1 - 0.002 17.9 0.1 1.8 8.6 0.1 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.1 EGE00539.1 - 0.013 15.5 2.3 0.013 15.5 1.6 4.5 4 1 2 6 6 6 0 Carnitine deficiency-associated protein 3 FlaG PF03646.10 EGE00539.1 - 8.1 6.6 6.5 0.9 9.7 0.1 2.5 3 0 0 3 3 3 0 FlaG protein NAD_binding_6 PF08030.7 EGE00540.1 - 7.2e-34 116.9 0.0 1.2e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGE00540.1 - 3.9e-23 81.3 0.0 1.5e-22 79.4 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EGE00540.1 - 2.6e-17 63.0 15.4 7.4e-17 61.6 5.2 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGE00540.1 - 2.8e-05 24.1 0.0 6.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGE00540.1 - 0.078 13.5 0.0 0.37 11.3 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Acetyltransf_13 PF13880.1 EGE00542.1 - 1.2e-27 95.4 0.0 3.4e-27 93.9 0.0 1.8 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EGE00542.1 - 6.6e-14 51.1 0.4 1.2e-13 50.3 0.3 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.1 EGE00542.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Dicty_REP PF05086.7 EGE00542.1 - 1.9 6.1 3.2 2.4 5.7 2.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 EGE00542.1 - 2.7 5.8 19.7 0.33 8.8 10.1 1.8 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Acyl-CoA_dh_1 PF00441.19 EGE00544.1 - 6.6e-25 87.9 0.3 1.2e-24 87.1 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGE00544.1 - 7.9e-25 87.6 0.1 2.3e-24 86.1 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGE00544.1 - 1.1e-17 63.2 0.0 2.5e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGE00544.1 - 6.8e-09 36.0 0.6 1.4e-08 35.0 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pet127 PF08634.5 EGE00545.1 - 3.9e-116 386.9 0.0 5.3e-116 386.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 SOR PF07682.6 EGE00545.1 - 0.079 11.5 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Sulphur oxygenase reductase LRR_6 PF13516.1 EGE00547.1 - 0.0016 18.3 7.1 2.1 8.6 0.1 6.5 5 0 0 5 5 5 1 Leucine Rich repeat SelP_N PF04592.9 EGE00547.1 - 1.6 8.0 15.4 0.43 9.9 1.8 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region CAP_N PF01213.14 EGE00548.1 - 2.2 7.4 6.3 3.3 6.9 4.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EGE00548.1 - 9.6 5.4 9.8 1.9 7.7 4.2 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator Gly_transf_sug PF04488.10 EGE00549.1 - 5e-18 65.3 0.0 8.8e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EGE00549.1 - 0.17 10.3 2.8 0.85 8.0 0.4 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain MOR2-PAG1_N PF14222.1 EGE00550.1 - 0.0037 16.0 0.6 0.0039 15.9 0.4 1.0 1 0 0 1 1 1 1 Cell morphogenesis N-terminal Use1 PF09753.4 EGE00550.1 - 0.033 13.6 2.7 0.043 13.2 1.9 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 TMEM51 PF15345.1 EGE00550.1 - 0.72 9.4 3.5 0.94 9.1 2.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Abhydrolase_6 PF12697.2 EGE00551.1 - 1.1e-15 58.1 1.7 1.6e-15 57.6 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE00551.1 - 0.00029 20.6 0.0 0.00055 19.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE00551.1 - 0.00061 19.4 0.2 0.004 16.7 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF4035 PF13227.1 EGE00551.1 - 0.0062 15.8 0.2 0.012 14.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4035) DUF3089 PF11288.3 EGE00551.1 - 0.071 12.2 0.1 0.31 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) EHN PF06441.7 EGE00551.1 - 0.11 12.4 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Bul1_N PF04425.7 EGE00552.1 - 1.9e-07 30.0 1.5 2.2e-06 26.5 1.1 2.1 1 1 0 1 1 1 1 Bul1 N terminus Arrestin_N PF00339.24 EGE00552.1 - 0.00064 19.5 0.0 0.002 17.9 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EGE00552.1 - 0.0041 16.3 0.0 0.0095 15.1 0.0 1.5 2 0 0 2 2 2 1 Bul1 C terminus Abhydrolase_5 PF12695.2 EGE00553.1 - 4.2e-11 42.7 0.0 8.8e-11 41.7 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE00553.1 - 1.6e-09 38.0 2.2 6.9e-09 35.9 1.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGE00553.1 - 2.6e-05 23.9 0.0 4.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EGE00553.1 - 0.00036 20.1 0.1 0.41 10.1 0.0 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EGE00553.1 - 0.00066 19.1 0.0 0.00085 18.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.9 EGE00553.1 - 0.012 14.8 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Peptidase_S9 PF00326.16 EGE00553.1 - 0.08 12.1 0.0 0.2 10.8 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF2235 PF09994.4 EGE00553.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) AA_permease PF00324.16 EGE00554.1 - 6.7e-135 450.1 45.3 7.9e-135 449.8 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE00554.1 - 2.4e-36 125.1 49.1 3e-36 124.8 34.0 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EGE00555.1 - 1.3e-24 86.6 39.5 2e-24 85.9 27.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Bacillus_PapR PF05968.6 EGE00555.1 - 0.058 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Bacillus PapR protein p450 PF00067.17 EGE00557.1 - 2.2e-55 188.0 0.0 2.8e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Thioesterase PF00975.15 EGE00558.1 - 3.2e-20 73.3 0.0 4.7e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EGE00558.1 - 2.6e-08 34.0 0.0 3.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE00558.1 - 0.0097 15.6 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cytokin_check_N PF10407.4 EGE00559.1 - 0.004 16.7 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Pkinase PF00069.20 EGE00560.1 - 1.6e-43 148.7 0.0 2.5e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EGE00560.1 - 6.1e-42 142.5 0.0 1.3e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EGE00560.1 - 9.6e-21 74.0 0.0 4.2e-20 71.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EGE00560.1 - 0.00048 19.5 0.0 0.078 12.5 0.0 3.1 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.9 EGE00560.1 - 0.0014 17.6 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGE00560.1 - 0.0016 17.8 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL PQQ_2 PF13360.1 EGE00560.1 - 0.041 13.3 0.1 0.2 11.0 0.0 2.0 1 1 1 2 2 2 0 PQQ-like domain Pro_isomerase PF00160.16 EGE00561.1 - 1.6e-50 171.3 0.1 3.4e-50 170.2 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EGE00561.1 - 4e-13 48.6 0.4 0.011 15.5 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 EGE00562.1 - 2.6e-129 432.0 9.6 3e-129 431.7 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pam17 PF08566.5 EGE00565.1 - 1.4e-70 236.5 0.1 1.9e-70 236.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Beta_elim_lyase PF01212.16 EGE00565.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase DUF2076 PF09849.4 EGE00565.1 - 0.11 12.5 0.3 0.61 10.0 0.1 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Fungal_trans_2 PF11951.3 EGE00566.1 - 2.2e-36 125.2 0.0 3.1e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE00566.1 - 9.5e-09 35.0 11.1 1.6e-08 34.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIB PF02201.13 EGE00567.1 - 1.4e-22 79.1 0.0 2.5e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain eIF2A PF08662.6 EGE00568.1 - 1.1e-38 132.9 7.3 7.7e-37 126.8 0.9 4.2 3 3 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 EGE00568.1 - 2.5e-07 30.4 0.0 6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGE00568.1 - 4.3e-07 29.4 0.0 1.2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE00568.1 - 2.4e-06 27.4 0.0 8.4e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGE00568.1 - 0.00019 21.2 0.1 0.1 12.4 0.0 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat DLH PF01738.13 EGE00569.1 - 1.5e-30 106.1 0.0 1.7e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGE00569.1 - 4.3e-07 29.7 0.0 5.7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE00569.1 - 0.0048 16.7 0.0 0.013 15.3 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF2828 PF11443.3 EGE00571.1 - 9.8e-167 555.3 0.5 1.3e-166 554.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Het-C PF07217.6 EGE00572.1 - 4.6e-266 883.8 0.0 6.6e-266 883.3 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Clr5 PF14420.1 EGE00573.1 - 2.7e-21 75.1 1.2 2.7e-21 75.1 0.8 2.3 2 0 0 2 2 2 1 Clr5 domain DUF4187 PF13821.1 EGE00573.1 - 0.12 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) TAXi_C PF14541.1 EGE00573.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Sensor PF13796.1 EGE00573.1 - 0.67 9.5 2.0 1.5 8.3 1.4 1.5 1 0 0 1 1 1 0 Putative sensor Phytase-like PF13449.1 EGE00576.1 - 4.3e-28 98.5 0.1 6.4e-28 97.9 0.0 1.4 1 1 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 EGE00576.1 - 0.09 11.7 0.1 1 8.2 0.0 2.5 3 0 0 3 3 3 0 SdiA-regulated Coatomer_WDAD PF04053.9 EGE00578.1 - 2.4e-145 484.7 0.0 3.6e-145 484.1 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EGE00578.1 - 2.7e-96 322.6 0.0 4.2e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EGE00578.1 - 3.1e-47 156.8 16.8 9.8e-09 34.7 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EGE00578.1 - 0.0014 16.8 5.0 0.19 9.8 0.0 3.5 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Clathrin PF00637.15 EGE00578.1 - 0.0017 17.9 0.2 0.093 12.3 0.0 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS Evr1_Alr PF04777.8 EGE00579.1 - 4.4e-26 90.5 4.4 4.9e-26 90.4 2.0 1.8 2 0 0 2 2 2 1 Erv1 / Alr family Bd3614-deam PF14439.1 EGE00579.1 - 0.023 14.5 0.1 5.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Bd3614-like deaminase DEK_C PF08766.6 EGE00580.1 - 0.0018 17.9 0.1 0.0043 16.7 0.1 1.6 1 0 0 1 1 1 1 DEK C terminal domain Adaptin_N PF01602.15 EGE00581.1 - 1.1e-139 466.1 3.3 1.3e-139 465.9 2.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGE00581.1 - 2.9e-30 105.4 0.1 2.1e-27 96.1 0.1 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGE00581.1 - 2e-18 66.4 3.2 1.1e-06 28.8 0.0 5.5 3 3 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EGE00581.1 - 6.7e-12 44.4 0.3 0.012 15.5 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EGE00581.1 - 6.2e-05 23.3 3.3 1 9.9 0.0 6.3 7 1 0 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 EGE00581.1 - 0.0017 17.7 0.2 1.4 8.2 0.0 3.5 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.18 EGE00581.1 - 0.0042 16.8 3.8 5.7 6.9 0.0 5.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 EGE00581.1 - 0.031 14.2 0.1 5.7 7.0 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Ribosomal_60s PF00428.14 EGE00581.1 - 1.8 9.0 9.6 5.5 7.4 3.4 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein TLD PF07534.11 EGE00582.1 - 2.6e-24 85.7 0.0 6.8e-15 55.2 0.0 2.2 2 0 0 2 2 2 2 TLD VID27 PF08553.5 EGE00583.1 - 3.1e-208 693.7 8.5 2.5e-192 641.1 5.4 2.0 1 1 1 2 2 2 2 VID27 cytoplasmic protein tRNA_m1G_MT PF01746.16 EGE00584.1 - 4.4e-31 107.9 4.0 1.2e-30 106.4 0.0 2.5 2 1 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Rsc14 PF08586.5 EGE00584.1 - 0.47 10.9 2.6 1.5 9.3 1.8 1.8 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit GRIM-19 PF06212.7 EGE00585.1 - 1.3e-20 73.4 0.2 2.6e-20 72.4 0.1 1.5 1 1 0 1 1 1 1 GRIM-19 protein Xpo1 PF08389.7 EGE00586.1 - 1.1e-11 44.8 8.5 8.2e-10 38.7 3.3 4.2 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EGE00586.1 - 0.0024 17.7 1.3 0.17 11.8 0.0 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cellulase PF00150.13 EGE00587.1 - 2.9e-08 33.2 4.0 1.6e-06 27.5 1.2 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 EGE00588.1 - 1.4e-42 143.1 36.1 3.1e-07 29.9 0.0 12.4 12 1 1 13 13 13 7 TPR repeat TPR_17 PF13431.1 EGE00588.1 - 2.1e-23 80.4 17.3 0.024 14.8 0.0 14.0 13 1 0 13 13 13 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGE00588.1 - 3.5e-19 68.9 39.6 0.0012 19.5 0.2 12.7 11 3 2 13 13 13 6 Tetratricopeptide repeat TPR_12 PF13424.1 EGE00588.1 - 1.7e-18 66.3 30.4 0.0011 18.8 0.2 11.5 10 2 3 13 13 13 7 Tetratricopeptide repeat TPR_1 PF00515.23 EGE00588.1 - 7.3e-18 63.3 35.9 0.018 14.6 0.1 13.7 15 1 0 15 15 15 7 Tetratricopeptide repeat TPR_2 PF07719.12 EGE00588.1 - 3e-17 61.0 49.5 0.021 14.7 0.1 15.5 17 0 0 17 17 16 6 Tetratricopeptide repeat TPR_14 PF13428.1 EGE00588.1 - 4.3e-16 57.9 39.0 0.061 13.9 0.2 16.0 12 4 5 18 18 18 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGE00588.1 - 4.5e-14 52.5 25.9 0.0012 19.1 0.3 10.0 9 2 2 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.1 EGE00588.1 - 1.6e-10 40.0 28.6 0.034 13.9 0.5 11.0 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGE00588.1 - 3.3e-08 32.7 9.3 0.86 9.5 0.0 9.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGE00588.1 - 1.6e-06 28.1 24.7 0.33 11.4 0.2 12.3 14 0 0 14 14 14 2 Tetratricopeptide repeat Apc3 PF12895.2 EGE00588.1 - 0.22 11.6 0.1 0.22 11.6 0.1 7.7 9 0 0 9 9 8 0 Anaphase-promoting complex, cyclosome, subunit 3 Apc5 PF12862.2 EGE00588.1 - 0.74 9.7 8.3 1.8 8.4 0.0 5.1 6 2 0 6 6 6 0 Anaphase-promoting complex subunit 5 DUF1767 PF08585.7 EGE00589.1 - 9.6e-16 57.8 0.1 1.5e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Vps51 PF08700.6 EGE00590.1 - 1.1e-24 86.1 0.0 2.3e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EGE00590.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 EGE00590.1 - 0.018 13.4 0.1 0.026 13.0 0.1 1.1 1 0 0 1 1 1 0 Dor1-like family COG2 PF06148.6 EGE00590.1 - 0.1 12.4 0.1 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Fes1 PF08609.5 EGE00590.1 - 0.12 12.9 0.1 0.85 10.1 0.0 2.2 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 WD40 PF00400.27 EGE00591.1 - 2.5e-05 23.9 0.0 0.066 13.1 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.10 EGE00591.1 - 0.027 13.5 0.0 0.063 12.3 0.0 1.6 1 0 0 1 1 1 0 CPSF A subunit region SAC3_GANP PF03399.11 EGE00592.1 - 8.3e-26 90.8 0.0 1.2e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGE00592.1 - 3.3e-21 75.5 0.0 7.3e-21 74.4 0.0 1.5 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 DUF2306 PF10067.4 EGE00593.1 - 7.8e-10 38.8 7.7 7.8e-10 38.8 5.3 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) Pro-kuma_activ PF09286.6 EGE00594.1 - 1.5e-35 122.3 0.0 3.7e-35 121.0 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGE00594.1 - 1.1e-09 37.8 0.1 4e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Subtilase family adh_short PF00106.20 EGE00595.1 - 1.1e-14 54.7 0.0 1.4e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE00595.1 - 2.2e-06 27.4 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGE00595.1 - 0.00023 21.0 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.4 EGE00596.1 - 9.5e-22 77.2 0.1 1.3e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGE00596.1 - 4.2e-07 30.5 0.0 8.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGE00596.1 - 6.3e-05 22.2 0.0 8.7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGE00596.1 - 0.00068 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EGE00596.1 - 0.0029 18.0 0.0 0.0051 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE00596.1 - 0.0037 17.0 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE00596.1 - 0.0051 17.2 0.0 0.009 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EGE00596.1 - 0.0059 15.6 0.0 0.0093 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Met_10 PF02475.11 EGE00596.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_26 PF13659.1 EGE00596.1 - 0.015 15.2 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EGE00596.1 - 0.03 13.8 0.0 0.094 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) TehB PF03848.9 EGE00596.1 - 0.06 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.14 EGE00596.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EGE00596.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.14 EGE00597.1 - 3.3e-32 110.1 0.0 5.1e-32 109.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Ustilago_mating PF05722.7 EGE00597.1 - 0.071 12.4 0.1 0.087 12.1 0.1 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Zn_clus PF00172.13 EGE00598.1 - 2.7e-08 33.5 5.8 7.1e-08 32.2 4.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 EGE00599.1 - 8.9e-22 77.9 0.0 2e-18 67.0 0.0 2.2 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD VGCC_beta4Aa_N PF12052.3 EGE00599.1 - 1.1 9.1 6.7 2 8.3 4.6 1.3 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal UDPGP PF01704.13 EGE00600.1 - 2.4e-44 151.5 0.0 2.8e-43 147.9 0.0 2.0 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EGE00600.1 - 0.0051 16.8 0.1 0.02 14.9 0.0 2.1 2 1 1 3 3 3 1 MobA-like NTP transferase domain Fer4_20 PF14691.1 EGE00600.1 - 0.043 13.4 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DUF3007 PF11460.3 EGE00600.1 - 0.16 12.0 0.4 0.34 10.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) zf-CCHC PF00098.18 EGE00601.1 - 2.4e-33 112.4 34.0 2e-07 30.6 0.6 5.4 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 EGE00601.1 - 7.5e-07 28.7 29.3 0.071 12.7 0.8 5.9 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.1 EGE00601.1 - 1.2e-05 24.8 21.5 0.038 13.7 0.0 5.0 4 1 1 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.1 EGE00601.1 - 0.006 16.0 0.7 0.006 16.0 0.5 5.7 4 2 2 6 6 6 4 Zinc knuckle Rad51 PF08423.6 EGE00602.1 - 2.7e-125 416.4 0.0 3.7e-125 416.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 EGE00602.1 - 2.8e-13 49.6 0.0 3.5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EGE00602.1 - 1.9e-09 37.2 0.0 2.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGE00602.1 - 2.6e-08 33.2 0.0 5.2e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 EGE00602.1 - 3.8e-08 33.3 2.1 7e-08 32.5 0.2 2.3 3 0 0 3 3 3 1 Helix-hairpin-helix domain RRP7 PF12923.2 EGE00603.1 - 9.5e-32 109.7 7.7 9.5e-32 109.7 5.4 2.5 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EGE00603.1 - 0.054 13.1 0.0 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT PF02985.17 EGE00605.1 - 1.5e-16 58.8 9.7 0.00017 21.4 0.0 8.3 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 EGE00605.1 - 2.1e-14 53.5 4.2 0.00012 22.3 0.0 5.6 3 3 2 5 5 5 4 HEAT repeats HEAT_EZ PF13513.1 EGE00605.1 - 5e-10 39.5 11.5 1.1e-05 25.7 0.0 7.0 8 1 1 9 9 9 2 HEAT-like repeat CLASP_N PF12348.3 EGE00605.1 - 4.6e-08 32.7 2.0 0.0057 16.0 0.0 4.1 4 0 0 4 4 4 2 CLASP N terminal DUF3535 PF12054.3 EGE00605.1 - 0.00032 19.4 0.6 0.00068 18.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) Arm PF00514.18 EGE00605.1 - 0.0015 18.2 1.6 19 5.2 0.1 4.9 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat MMS19_N PF14500.1 EGE00605.1 - 0.0018 17.6 0.3 1.4 8.0 0.3 2.8 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II Apc4 PF12896.2 EGE00606.1 - 1.4e-61 207.4 1.3 2.3e-61 206.7 0.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EGE00606.1 - 5e-16 57.9 0.0 1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain VWA PF00092.23 EGE00609.1 - 1.1e-10 41.5 0.0 1.7e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGE00609.1 - 1.7e-08 34.7 0.0 2.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EGE00609.1 - 0.00045 20.0 0.0 0.00061 19.6 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.1 EGE00609.1 - 0.045 13.4 0.0 0.087 12.5 0.0 1.4 1 1 0 1 1 1 0 von Willebrand factor type A domain Tannase PF07519.6 EGE00610.1 - 1.6e-98 330.5 0.1 1.9e-98 330.2 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 EGE00610.1 - 0.00098 18.7 0.0 0.0016 18.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGE00610.1 - 0.00099 19.0 0.0 0.0019 18.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE00610.1 - 0.0043 16.8 0.0 0.22 11.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Zn_clus PF00172.13 EGE00611.1 - 5.1e-09 35.9 9.6 1e-08 34.9 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGE00611.1 - 1.1e-07 30.7 5.8 8.5e-07 27.8 0.2 3.0 2 1 1 3 3 3 2 Fungal specific transcription factor domain Tox-HNH-HHH PF15637.1 EGE00612.1 - 0.017 14.9 0.5 0.081 12.7 0.1 2.1 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif APH PF01636.18 EGE00613.1 - 1e-12 48.3 0.0 1.6e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family PRTase_1 PF11202.3 EGE00613.1 - 0.094 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) Methyltransf_16 PF10294.4 EGE00614.1 - 1.1e-22 80.3 0.0 1.8e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EGE00614.1 - 0.0031 17.2 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE00614.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EGE00614.1 - 0.12 12.9 0.0 0.34 11.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.22 EGE00615.1 - 2.9e-26 92.3 0.0 3.4e-23 82.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGE00615.1 - 7.6e-12 45.7 0.5 0.00043 20.3 0.0 3.5 3 1 1 4 4 4 3 AAA domain ABC_membrane PF00664.18 EGE00615.1 - 1.7e-09 37.4 2.3 1.5e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EGE00615.1 - 7.5e-08 31.8 0.3 0.0004 19.6 0.0 3.0 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_5 PF07728.9 EGE00615.1 - 0.034 13.8 0.4 11 5.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EGE00615.1 - 0.044 13.2 0.1 0.085 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EGE00615.1 - 0.1 12.5 0.1 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.20 EGE00615.1 - 0.12 11.9 0.2 0.45 9.9 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EGE00615.1 - 0.14 11.5 0.1 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain VPS28 PF03997.7 EGE00616.1 - 1.3e-60 204.2 0.4 1.5e-60 204.0 0.3 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 EGE00616.1 - 0.93 9.3 4.1 0.9 9.3 0.5 2.1 2 0 0 2 2 2 0 Gas vesicle protein G Noc2 PF03715.8 EGE00617.1 - 2.3e-121 404.3 0.0 2.3e-121 404.3 0.0 1.8 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.7 EGE00617.1 - 0.055 11.3 0.0 0.055 11.3 0.0 3.9 3 1 1 4 4 4 0 Nop14-like family Piwi PF02171.12 EGE00618.1 - 1.2e-69 234.6 0.0 1.7e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EGE00618.1 - 1e-15 56.8 0.0 2.3e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EGE00618.1 - 5e-13 48.5 0.2 2.2e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 PAZ domain MoaC PF01967.16 EGE00619.1 - 5.4e-41 139.4 0.1 9.9e-41 138.5 0.0 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EGE00619.1 - 1.4e-35 121.7 0.0 9e-35 119.1 0.0 2.2 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EGE00619.1 - 1.3e-22 80.6 0.1 2.5e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EGE00619.1 - 0.00025 21.1 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EGE00619.1 - 0.00093 19.2 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain AA_permease PF00324.16 EGE00621.1 - 2e-140 468.3 37.6 2.4e-140 468.0 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE00621.1 - 2.6e-36 125.1 38.6 3.1e-36 124.8 26.7 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 EGE00621.1 - 0.088 11.2 0.0 0.14 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) ABC_tran PF00005.22 EGE00622.1 - 8.9e-09 35.7 0.0 1.9e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EGE00622.1 - 0.00029 20.3 0.0 0.00066 19.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EGE00622.1 - 0.00041 20.3 0.0 0.00057 19.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGE00622.1 - 0.0086 16.8 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EGE00622.1 - 0.017 15.5 0.0 0.054 13.9 0.0 1.8 2 1 0 2 2 1 0 Miro-like protein MMR_HSR1 PF01926.18 EGE00622.1 - 0.018 14.9 0.0 0.031 14.2 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EGE00622.1 - 0.019 15.3 0.0 0.027 14.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGE00622.1 - 0.019 14.9 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGE00622.1 - 0.022 14.4 0.0 0.067 12.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 EGE00622.1 - 0.029 13.8 0.0 0.066 12.6 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EGE00622.1 - 0.03 14.4 0.0 0.051 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EGE00622.1 - 0.033 13.8 0.1 0.11 12.2 0.0 1.9 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EGE00622.1 - 0.064 12.6 0.0 0.083 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGE00622.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGE00622.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EGE00622.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 2OG-FeII_Oxy_3 PF13640.1 EGE00624.1 - 0.00075 19.9 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 EGE00625.1 - 2.4e-07 30.3 0.1 0.01 15.7 0.0 5.3 7 0 0 7 7 7 2 WD domain, G-beta repeat IKI3 PF04762.7 EGE00625.1 - 6.6e-06 24.2 0.0 1.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 IKI3 family Apc4_WD40 PF12894.2 EGE00625.1 - 0.15 11.6 0.0 4.7 6.8 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S25 PF03297.10 EGE00626.1 - 8.3e-27 93.2 1.9 1e-26 92.9 1.3 1.1 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.7 EGE00626.1 - 0.0054 16.2 0.1 0.0081 15.6 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 EGE00626.1 - 0.028 14.5 0.1 0.039 14.0 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.2 EGE00626.1 - 0.029 14.0 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.7 EGE00626.1 - 0.034 13.8 0.1 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 HTH domain TrmB PF01978.14 EGE00626.1 - 0.042 13.5 0.3 0.065 12.9 0.2 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 EGE00626.1 - 0.1 12.3 0.1 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_24 PF13412.1 EGE00626.1 - 0.14 11.5 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cyt-b5 PF00173.23 EGE00627.1 - 1.9e-07 30.8 0.0 3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gtr1_RagA PF04670.7 EGE00628.1 - 2.5e-71 239.5 0.9 3.4e-71 239.0 0.3 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EGE00628.1 - 4.5e-05 22.7 0.0 7.9e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EGE00628.1 - 0.0011 19.4 0.0 0.0027 18.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGE00628.1 - 0.0014 17.8 0.0 0.0035 16.5 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Pkinase PF00069.20 EGE00629.1 - 1.1e-14 54.1 0.0 3.1e-14 52.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGE00629.1 - 0.0016 18.2 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family His_Phos_2 PF00328.17 EGE00630.1 - 8.7e-21 74.6 0.0 4.5e-20 72.2 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lactamase_B_2 PF12706.2 EGE00631.1 - 3.2e-30 105.1 0.1 5.3e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EGE00631.1 - 9.1e-26 89.1 0.2 9.6e-25 85.8 0.0 2.6 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B PF00753.22 EGE00631.1 - 7e-08 32.3 0.2 1.3e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Methyltransf_23 PF13489.1 EGE00632.1 - 2e-19 69.8 0.1 3.5e-16 59.3 0.0 2.7 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 EGE00632.1 - 4.1e-17 62.1 0.0 2.5e-14 53.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EGE00632.1 - 9.5e-17 61.2 0.0 1.6e-14 54.1 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE00632.1 - 5.1e-16 59.2 0.1 4.6e-15 56.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE00632.1 - 1.5e-15 57.4 0.0 7.9e-10 39.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EGE00632.1 - 5.2e-15 55.6 0.1 1.8e-14 53.9 0.1 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE00632.1 - 6.5e-09 35.8 0.0 6.7e-08 32.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EGE00632.1 - 9.4e-09 34.7 0.0 1.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 EGE00632.1 - 2.9e-06 26.8 0.0 0.00028 20.3 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.9 EGE00632.1 - 1.3e-05 24.6 0.0 5.9e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.7 EGE00632.1 - 2.8e-05 23.5 0.0 0.00043 19.7 0.0 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW TehB PF03848.9 EGE00632.1 - 0.00025 20.2 0.0 0.00046 19.3 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.13 EGE00632.1 - 0.00031 20.0 0.2 0.66 9.2 0.0 2.5 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Pox_MCEL PF03291.11 EGE00632.1 - 0.00042 19.2 0.0 0.0073 15.2 0.0 2.2 1 1 0 1 1 1 1 mRNA capping enzyme Ubie_methyltran PF01209.13 EGE00632.1 - 0.0013 17.9 0.0 0.019 14.1 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 EGE00632.1 - 0.0019 16.9 0.0 0.003 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TPMT PF05724.6 EGE00632.1 - 0.0019 17.6 0.0 0.0045 16.4 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.14 EGE00632.1 - 0.011 15.2 0.0 0.032 13.7 0.0 1.7 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.10 EGE00632.1 - 0.015 14.4 0.0 4.4 6.3 0.0 2.2 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G FmrO PF07091.6 EGE00632.1 - 0.036 13.0 0.0 0.063 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) UPF0146 PF03686.8 EGE00632.1 - 0.055 13.2 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Methyltransf_32 PF13679.1 EGE00632.1 - 0.055 13.1 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.7 EGE00632.1 - 0.096 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_4 PF02390.12 EGE00632.1 - 0.13 11.3 0.0 0.31 10.0 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase AflR PF08493.5 EGE00633.1 - 0.011 14.7 8.8 0.025 13.6 6.1 1.5 1 1 0 1 1 1 0 Aflatoxin regulatory protein Zip PF02535.17 EGE00634.1 - 0.0021 17.1 23.5 0.003 16.6 16.3 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter SASRP1 PF15160.1 EGE00634.1 - 0.15 11.2 10.6 0.2 10.8 7.4 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 DUF515 PF04415.7 EGE00634.1 - 5.9 5.0 12.8 8.6 4.4 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Secretin_N_2 PF07655.8 EGE00634.1 - 8.1 6.9 15.4 1.8 9.0 7.8 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain ORC4_C PF14629.1 EGE00636.1 - 7.6e-50 169.1 0.0 1.4e-49 168.3 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EGE00636.1 - 5.6e-14 52.5 1.2 6.2e-11 42.6 0.1 3.3 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EGE00636.1 - 0.00015 20.7 0.0 0.00025 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.7 EGE00636.1 - 0.00087 18.9 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 EGE00636.1 - 0.0014 18.8 0.0 0.0044 17.2 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGE00636.1 - 0.0024 17.5 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EGE00636.1 - 0.0029 17.7 0.1 0.047 13.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGE00636.1 - 0.012 15.4 0.1 0.036 13.8 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EGE00636.1 - 0.032 13.7 0.1 0.095 12.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EGE00636.1 - 0.051 12.7 0.0 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 EGE00636.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family PIF1 PF05970.9 EGE00636.1 - 0.17 10.8 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase DUF3439 PF11921.3 EGE00636.1 - 2.6 7.7 6.8 7.7 6.2 4.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PHD PF00628.24 EGE00637.1 - 1.8e-06 27.5 9.5 4.3e-06 26.3 6.6 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EGE00637.1 - 5.3e-06 26.8 0.1 5.3e-06 26.8 0.1 2.6 3 0 0 3 3 3 1 SET domain PHD_2 PF13831.1 EGE00637.1 - 0.26 10.6 5.5 0.51 9.6 3.8 1.5 1 0 0 1 1 1 0 PHD-finger DUF3682 PF12446.3 EGE00638.1 - 2.2 8.5 8.3 2.9 8.1 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) ArfGap PF01412.13 EGE00639.1 - 5.6e-37 126.0 0.0 1.1e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 EGE00639.1 - 0.17 11.7 0.1 0.82 9.5 0.0 2.1 2 0 0 2 2 2 0 UBA/TS-N domain VGCC_beta4Aa_N PF12052.3 EGE00639.1 - 2.3 8.1 6.8 9.9 6.1 0.3 2.8 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Glyco_transf_22 PF03901.12 EGE00640.1 - 8.2e-81 272.1 18.3 1e-80 271.8 12.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.16 EGE00641.1 - 1.1e-102 343.3 0.0 1.3e-102 343.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EGE00641.1 - 0.006 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase ABC_membrane PF00664.18 EGE00642.1 - 4.1e-56 190.4 32.1 5.3e-33 114.6 13.2 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EGE00642.1 - 2.7e-47 160.4 0.9 4.6e-27 94.9 0.1 3.5 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EGE00642.1 - 7.2e-10 39.2 0.1 0.0012 18.8 0.1 4.0 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EGE00642.1 - 4.5e-06 26.5 0.1 0.046 13.6 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EGE00642.1 - 7.4e-06 26.4 0.5 0.23 11.9 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EGE00642.1 - 1.3e-05 26.0 0.0 0.22 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGE00642.1 - 6.4e-05 22.2 6.8 0.12 11.5 1.4 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGE00642.1 - 6.6e-05 22.3 1.2 0.11 12.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGE00642.1 - 0.00018 21.9 0.2 0.35 11.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGE00642.1 - 0.00024 21.1 4.7 0.088 12.7 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGE00642.1 - 0.00045 19.4 0.6 0.27 10.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ArgK PF03308.11 EGE00642.1 - 0.0012 17.6 2.1 0.43 9.3 0.1 2.4 2 0 0 2 2 2 2 ArgK protein Zeta_toxin PF06414.7 EGE00642.1 - 0.0048 16.0 0.1 2.7 7.0 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.18 EGE00642.1 - 0.0059 16.4 2.3 0.23 11.2 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 EGE00642.1 - 0.0082 15.6 1.4 2.8 7.2 0.2 2.8 3 0 0 3 3 3 1 AAA-like domain AAA_18 PF13238.1 EGE00642.1 - 0.015 15.5 0.0 5 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGE00642.1 - 0.017 15.2 0.4 6.4 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EGE00642.1 - 0.017 14.5 0.3 2.4 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 EGE00642.1 - 0.034 13.7 0.2 0.034 13.7 0.2 2.9 2 1 0 2 2 2 0 IncA protein DUF87 PF01935.12 EGE00642.1 - 0.04 13.7 4.0 0.1 12.3 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_15 PF13175.1 EGE00642.1 - 0.07 12.1 0.1 9.2 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain YqzM PF14141.1 EGE00642.1 - 0.071 12.9 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 YqzM-like protein AAA_30 PF13604.1 EGE00642.1 - 0.11 12.0 2.4 1.8 8.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EGE00642.1 - 0.18 11.5 0.3 18 5.0 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EGE00642.1 - 0.3 11.0 0.0 0.3 11.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain AA_permease_2 PF13520.1 EGE00643.1 - 1.2e-41 142.6 46.3 4.1e-41 140.9 30.7 2.1 1 1 0 1 1 1 1 Amino acid permease Tyr-DNA_phospho PF06087.7 EGE00644.1 - 8.1e-145 482.8 0.0 9.3e-145 482.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EGE00644.1 - 0.0004 20.1 0.0 0.038 13.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain ACBP PF00887.14 EGE00645.1 - 1.4e-22 79.1 0.4 1.6e-22 78.9 0.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein U-box PF04564.10 EGE00646.1 - 3e-24 84.7 0.1 5.7e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EGE00646.1 - 1.5e-15 56.5 4.2 3.6e-15 55.3 0.4 2.4 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 EGE00646.1 - 1e-08 34.3 3.2 0.00016 21.3 0.9 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGE00646.1 - 1.1e-06 29.0 2.4 8e-05 23.2 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGE00646.1 - 1.4e-06 27.6 2.9 7.7e-05 22.1 1.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGE00646.1 - 1.3e-05 25.4 0.5 0.00061 20.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGE00646.1 - 0.00038 20.3 3.5 0.037 13.9 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-Nse PF11789.3 EGE00646.1 - 0.00077 18.9 0.1 0.0035 16.8 0.0 1.9 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit TPR_17 PF13431.1 EGE00646.1 - 0.0015 18.5 3.0 0.014 15.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGE00646.1 - 0.0017 18.7 0.1 0.28 11.9 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EGE00646.1 - 0.0087 16.1 0.1 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 zf-RING_UBOX PF13445.1 EGE00646.1 - 0.12 12.0 0.0 0.37 10.5 0.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger TIM PF00121.13 EGE00649.1 - 6.8e-45 153.0 0.0 2.2e-44 151.3 0.0 1.7 1 1 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 EGE00650.1 - 1.3e-41 141.5 0.1 1.5e-41 141.3 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2620 PF10941.3 EGE00650.1 - 0.032 14.2 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2620 DHO_dh PF01180.16 EGE00651.1 - 1.7e-63 214.3 0.5 3.7e-55 186.9 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 EGE00651.1 - 0.00012 21.4 0.4 0.33 10.1 0.0 2.5 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 EGE00651.1 - 0.00079 18.3 0.0 0.0022 16.9 0.0 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Mnd1 PF03962.10 EGE00652.1 - 4.6e-44 150.3 5.4 6e-44 149.9 3.7 1.1 1 0 0 1 1 1 1 Mnd1 family IncA PF04156.9 EGE00652.1 - 0.0033 17.0 3.6 0.0044 16.6 2.5 1.4 1 0 0 1 1 1 1 IncA protein HTH_20 PF12840.2 EGE00652.1 - 0.012 15.4 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Fmp27_WPPW PF10359.4 EGE00652.1 - 0.034 12.5 3.0 0.85 7.9 0.7 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain TBPIP PF07106.8 EGE00652.1 - 0.049 13.1 4.9 0.11 12.0 2.9 2.0 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SpoVR PF04293.8 EGE00652.1 - 0.049 11.9 2.9 0.082 11.2 2.0 1.3 1 0 0 1 1 1 0 SpoVR like protein AATF-Che1 PF13339.1 EGE00652.1 - 0.061 13.4 2.4 0.094 12.8 1.4 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF1465 PF07323.7 EGE00652.1 - 0.1 12.1 1.7 0.55 9.7 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Snapin_Pallidin PF14712.1 EGE00652.1 - 0.13 12.5 2.6 2.1 8.6 0.9 2.7 2 1 0 2 2 2 0 Snapin/Pallidin Fib_alpha PF08702.5 EGE00652.1 - 0.45 10.6 9.1 0.46 10.6 3.6 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 EGE00652.1 - 0.52 9.8 15.4 0.32 10.4 0.8 3.7 2 1 2 4 4 4 0 Septum formation initiator CCDC-167 PF15188.1 EGE00652.1 - 1.1 9.2 7.6 2.7 7.9 0.1 2.9 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 Macoilin PF09726.4 EGE00652.1 - 1.5 7.0 7.8 1.7 6.8 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein SlyX PF04102.7 EGE00652.1 - 2.2 8.7 6.1 2.2 8.7 1.1 2.7 2 1 0 2 2 2 0 SlyX BRE1 PF08647.6 EGE00652.1 - 3.3 7.7 9.7 24 4.9 5.7 3.0 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF904 PF06005.7 EGE00652.1 - 3.8 7.8 10.4 85 3.5 7.2 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EGE00652.1 - 6.6 6.6 9.6 3.1 7.6 1.1 3.4 2 1 0 2 2 2 0 Basic region leucine zipper Bap31 PF05529.7 EGE00652.1 - 9.8 5.5 8.2 5.7 6.3 2.2 2.1 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like UAF_Rrn10 PF05234.6 EGE00653.1 - 6.4e-05 22.9 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 UAF complex subunit Rrn10 WD40 PF00400.27 EGE00654.1 - 3.1e-30 102.9 11.9 7.3e-09 35.1 0.4 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 EGE00655.1 - 4.7e-90 301.9 0.2 5.8e-90 301.6 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE00655.1 - 1.2e-06 28.3 8.8 2.4e-06 27.3 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.12 EGE00659.1 - 1.6e-10 40.6 0.1 2.9e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGE00659.1 - 7.7e-08 32.4 0.2 1.6e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 EGE00659.1 - 0.0035 17.3 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.11 EGE00659.1 - 0.0063 16.2 0.1 0.017 14.8 0.1 1.7 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain PH_6 PF15406.1 EGE00660.1 - 0.0098 15.9 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain eIF-5_eIF-2B PF01873.12 EGE00662.1 - 2.4e-44 149.9 0.1 4e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EGE00662.1 - 0.075 13.3 0.7 0.25 11.6 0.5 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF2413 PF10310.4 EGE00662.1 - 0.79 8.4 12.6 1 8.0 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Arc_trans_TRASH PF08394.5 EGE00662.1 - 1.1 9.4 7.0 0.95 9.6 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain PepSY_2 PF13670.1 EGE00662.1 - 8.9 6.2 9.3 10 6.0 2.5 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain AIM24 PF01987.12 EGE00663.1 - 1.5e-56 191.2 0.2 1.8e-56 190.9 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 MamL-1 PF09596.5 EGE00664.1 - 0.15 11.8 1.4 19 5.1 0.1 2.8 2 0 0 2 2 2 0 MamL-1 domain bZIP_1 PF00170.16 EGE00666.1 - 1.5e-06 28.0 3.7 3.1e-06 27.0 2.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor Halo_GVPC PF05465.8 EGE00666.1 - 0.92 9.5 2.2 0.6 10.0 0.2 1.8 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Ras PF00071.17 EGE00667.1 - 8.8e-41 138.9 0.0 1.2e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE00667.1 - 2.9e-14 53.5 0.0 4.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE00667.1 - 5.2e-12 45.3 0.0 2e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGE00667.1 - 6.9e-05 22.3 0.0 0.00026 20.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGE00667.1 - 0.00011 21.3 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGE00667.1 - 0.00091 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGE00667.1 - 0.0029 17.7 0.0 0.0079 16.3 0.0 1.7 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EGE00667.1 - 0.0042 16.5 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EGE00667.1 - 0.0047 16.8 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 EGE00667.1 - 0.0089 15.2 0.0 0.017 14.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit NACHT PF05729.7 EGE00667.1 - 0.0099 15.5 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 1 NACHT domain DUF258 PF03193.11 EGE00667.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EGE00667.1 - 0.019 15.2 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EGE00667.1 - 0.053 13.5 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 EGE00667.1 - 0.06 13.0 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EGE00667.1 - 0.075 12.5 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ADH_N PF08240.7 EGE00668.1 - 4.9e-33 113.1 2.7 1.5e-32 111.5 0.2 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGE00668.1 - 7.1e-23 80.5 0.2 1.4e-22 79.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EGE00668.1 - 9e-06 26.2 0.0 2.9e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGE00668.1 - 0.0015 19.4 0.1 0.0038 18.1 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGE00668.1 - 0.012 14.9 0.1 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.16 EGE00668.1 - 0.052 13.3 0.3 0.46 10.3 0.2 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HI0933_like PF03486.9 EGE00668.1 - 0.055 11.9 0.1 0.076 11.4 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EGE00668.1 - 0.071 12.6 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PrmA PF06325.8 EGE00668.1 - 0.094 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_hydro_2 PF00703.16 EGE00669.1 - 2e-12 47.4 0.0 1.5e-11 44.7 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EGE00669.1 - 5.4e-10 39.0 0.0 1.1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain FAD-oxidase_C PF02913.14 EGE00670.1 - 5.8e-57 192.8 0.1 1e-56 192.0 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGE00670.1 - 2.5e-26 91.8 0.1 1.1e-24 86.4 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain EST1_DNA_bind PF10373.4 EGE00671.1 - 2.4e-10 40.0 0.0 3.5e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain PAF-AH_p_II PF03403.8 EGE00677.1 - 5e-16 57.9 0.0 2.3e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EGE00677.1 - 2.6e-09 37.0 0.1 4.2e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE00677.1 - 2.1e-07 31.0 0.2 3.2e-07 30.4 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGE00677.1 - 7.3e-05 21.7 0.0 0.00013 20.9 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EGE00677.1 - 0.077 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Chlorophyllase PF07224.6 EGE00677.1 - 0.09 11.5 0.1 0.17 10.6 0.1 1.3 1 1 0 1 1 1 0 Chlorophyllase DUF3115 PF11312.3 EGE00678.1 - 4.8e-90 301.6 0.0 6.1e-90 301.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Band_7 PF01145.20 EGE00680.1 - 7.5e-25 87.8 6.8 1.1e-24 87.3 4.4 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family GatB_Yqey PF02637.13 EGE00680.1 - 0.023 14.4 0.6 0.041 13.5 0.4 1.5 1 0 0 1 1 1 0 GatB domain DUF2884 PF11101.3 EGE00680.1 - 0.028 13.7 0.7 0.05 12.9 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) UcrQ PF02939.11 EGE00681.1 - 9.4e-27 92.6 0.3 1.2e-26 92.3 0.2 1.0 1 0 0 1 1 1 1 UcrQ family Ribosomal_L7Ae PF01248.21 EGE00682.1 - 3.3e-18 64.9 1.2 3.3e-18 64.9 0.8 2.5 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Avirulence PF03377.8 EGE00682.1 - 0.052 12.2 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA FSIP1 PF15554.1 EGE00684.1 - 0.083 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 FSIP1 family MMR_HSR1_C PF08438.5 EGE00685.1 - 3.3e-32 110.9 0.0 7e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EGE00685.1 - 1.8e-15 56.9 0.0 4.2e-15 55.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGE00685.1 - 1.9e-05 23.9 0.0 0.00066 18.9 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGE00685.1 - 0.0015 17.9 0.6 0.54 9.6 0.0 2.7 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EGE00685.1 - 0.007 15.1 0.4 0.023 13.4 0.0 2.0 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 EGE00685.1 - 0.012 15.4 2.0 0.27 11.0 0.3 2.8 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 EGE00685.1 - 0.022 14.2 0.2 6.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EGE00685.1 - 0.042 14.1 0.3 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter VirB8 PF04335.8 EGE00685.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 VirB8 protein AAA_30 PF13604.1 EGE00685.1 - 0.11 12.0 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EGE00685.1 - 0.13 11.4 0.1 0.32 10.1 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SET PF00856.23 EGE00687.1 - 0.002 18.4 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 SET domain Fungal_trans PF04082.13 EGE00690.1 - 3.3e-30 104.8 1.0 6.3e-30 103.9 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE00690.1 - 1.1e-09 37.9 11.7 1.8e-09 37.3 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 EGE00690.1 - 4.2 5.5 6.3 9.5 4.3 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein Transketolase_N PF00456.16 EGE00691.1 - 5.9e-142 472.3 0.0 1.4e-141 471.1 0.0 1.6 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EGE00691.1 - 5.4e-46 156.3 0.0 8.8e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EGE00691.1 - 9.1e-07 28.0 0.0 0.00041 19.3 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 EGE00691.1 - 0.00031 20.6 0.1 0.00069 19.5 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 EGE00691.1 - 0.0057 15.4 0.1 0.01 14.5 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_N PF02776.13 EGE00691.1 - 0.17 11.3 2.7 3.3 7.1 0.0 2.8 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGE00691.1 - 0.38 10.2 8.6 0.074 12.6 1.2 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Spermine_synth PF01564.12 EGE00692.1 - 9e-89 296.6 0.0 1.1e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EGE00692.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE00692.1 - 0.0032 17.9 0.2 0.015 15.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.11 EGE00692.1 - 0.0034 16.4 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_18 PF12847.2 EGE00692.1 - 0.0073 16.8 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE00692.1 - 0.023 14.0 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 EGE00692.1 - 0.044 13.5 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain bZIP_1 PF00170.16 EGE00693.1 - 1.8e-08 34.2 9.7 3e-08 33.5 6.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor TMF_TATA_bd PF12325.3 EGE00693.1 - 0.00013 21.7 2.2 0.0002 21.0 1.5 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.10 EGE00693.1 - 0.0017 18.1 11.5 0.016 15.0 8.0 2.1 1 1 0 1 1 1 1 Basic region leucine zipper Macoilin PF09726.4 EGE00693.1 - 0.0032 15.8 3.6 0.0041 15.4 2.5 1.1 1 0 0 1 1 1 1 Transmembrane protein ASD2 PF08687.6 EGE00693.1 - 0.0038 16.5 1.2 0.0047 16.3 0.9 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 bZIP_Maf PF03131.12 EGE00693.1 - 0.0088 16.3 10.7 0.0088 16.3 7.4 1.4 1 1 0 1 1 1 1 bZIP Maf transcription factor CENP-F_leu_zip PF10473.4 EGE00693.1 - 0.011 15.5 3.3 0.016 15.0 2.3 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CcmH PF03918.9 EGE00693.1 - 0.022 13.7 0.6 0.041 12.8 0.4 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein TMF_DNA_bd PF12329.3 EGE00693.1 - 0.029 14.1 3.4 0.045 13.5 2.3 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.6 EGE00693.1 - 0.031 14.1 0.3 0.047 13.5 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) EAP30 PF04157.11 EGE00693.1 - 0.033 13.3 2.6 0.043 12.9 1.8 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family DUF2400 PF09674.5 EGE00693.1 - 0.087 12.5 0.5 0.12 12.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2419 PF10343.4 EGE00693.1 - 0.11 11.6 0.2 0.16 11.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) IncA PF04156.9 EGE00693.1 - 0.22 11.0 4.5 0.29 10.6 3.1 1.1 1 0 0 1 1 1 0 IncA protein Tup_N PF08581.5 EGE00693.1 - 0.33 11.1 4.1 0.37 11.0 1.4 1.9 1 1 1 2 2 2 0 Tup N-terminal EMP24_GP25L PF01105.19 EGE00693.1 - 0.47 10.1 2.6 0.64 9.7 1.8 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CDC45 PF02724.9 EGE00695.1 - 5.5 4.8 17.4 6.5 4.6 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EGE00695.1 - 9.5 5.5 14.7 14 4.9 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_polI_A34 PF08208.6 EGE00696.1 - 0.00094 18.9 14.3 0.00094 18.9 9.9 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 MIP-T3 PF10243.4 EGE00696.1 - 0.01 14.3 15.7 0.01 14.3 10.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 YqfQ PF14181.1 EGE00696.1 - 0.015 15.3 9.0 0.019 15.0 6.2 1.1 1 0 0 1 1 1 0 YqfQ-like protein Peptidase_U57 PF05582.7 EGE00696.1 - 0.17 10.7 4.1 0.2 10.6 2.9 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF2413 PF10310.4 EGE00696.1 - 0.2 10.4 8.5 0.23 10.2 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF3464 PF11947.3 EGE00696.1 - 0.24 10.8 8.2 0.3 10.5 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) FLO_LFY PF01698.11 EGE00696.1 - 0.26 10.0 7.9 0.27 10.0 5.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Zip PF02535.17 EGE00696.1 - 0.29 10.0 0.8 0.35 9.8 0.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 EGE00696.1 - 0.47 10.3 3.8 0.5 10.2 2.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pex16 PF08610.5 EGE00696.1 - 0.62 9.0 4.3 0.76 8.7 3.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4407 PF14362.1 EGE00696.1 - 0.69 8.8 4.8 0.77 8.6 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.9 EGE00696.1 - 0.75 7.7 9.4 0.7 7.8 6.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1168 PF06658.7 EGE00696.1 - 0.78 9.2 24.5 1.1 8.7 17.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF4337 PF14235.1 EGE00696.1 - 0.98 9.2 5.9 1.3 8.8 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Borrelia_P83 PF05262.6 EGE00696.1 - 1.1 7.4 10.9 1.1 7.4 7.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein EIIBC-GUT_N PF03612.9 EGE00696.1 - 1.5 8.4 5.5 1.9 8.0 3.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TAF1D PF15333.1 EGE00696.1 - 1.7 8.3 15.5 2.3 7.9 10.8 1.2 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D YihI PF04220.7 EGE00696.1 - 1.9 7.7 21.0 2.6 7.3 14.6 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) DUF2201_N PF13203.1 EGE00696.1 - 1.9 7.5 7.7 1.8 7.6 5.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DDHD PF02862.12 EGE00696.1 - 2.1 8.0 11.7 2.7 7.7 8.1 1.1 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 EGE00696.1 - 2.5 6.6 11.0 2.5 6.6 7.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AIF_C PF14721.1 EGE00696.1 - 2.6 8.2 7.5 3.4 7.9 5.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Band_3_cyto PF07565.8 EGE00696.1 - 2.6 7.4 5.6 3.1 7.2 3.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF1510 PF07423.6 EGE00696.1 - 2.9 7.1 15.0 3.7 6.8 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HSP90 PF00183.13 EGE00696.1 - 4.3 5.6 14.3 5.3 5.3 9.9 1.0 1 0 0 1 1 1 0 Hsp90 protein Di19_C PF14571.1 EGE00696.1 - 4.3 7.6 10.3 6.4 7.1 7.2 1.2 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal DUF4175 PF13779.1 EGE00696.1 - 4.5 4.8 14.8 5 4.6 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Rtf2 PF04641.7 EGE00696.1 - 5.3 6.1 17.5 7.2 5.7 12.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Sec62 PF03839.11 EGE00696.1 - 7.3 5.9 14.9 8.8 5.6 10.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Apt1 PF10351.4 EGE00696.1 - 9.3 4.9 13.3 11 4.7 9.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain G-alpha PF00503.15 EGE00697.1 - 1e-113 379.9 0.1 1.3e-113 379.6 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGE00697.1 - 1.3e-13 50.5 1.4 4.6e-09 35.7 0.0 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGE00697.1 - 1.8e-06 27.3 0.1 0.0026 16.9 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EGE00697.1 - 0.0021 18.5 0.1 0.31 11.5 0.0 2.9 2 2 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EGE00697.1 - 0.035 13.6 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGE00697.1 - 0.047 13.6 0.0 7.6 6.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGE00697.1 - 0.077 12.4 0.0 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF1713 PF08213.6 EGE00698.1 - 2.2e-12 46.3 20.7 4.5e-12 45.3 14.3 1.6 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 EGE00698.1 - 0.013 15.4 0.7 0.027 14.4 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial protein Pet20 DUF1202 PF06717.6 EGE00698.1 - 8 5.6 9.7 4.1 6.5 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1202) ATP-synt_C PF00137.16 EGE00699.1 - 2e-33 114.1 29.2 3.8e-19 68.3 8.9 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EGE00699.1 - 0.18 11.3 2.9 0.11 12.0 0.4 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A ABA_GPCR PF12430.3 EGE00699.1 - 0.21 10.6 1.1 3.3 6.7 0.1 2.1 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor p450 PF00067.17 EGE00701.1 - 5.1e-57 193.4 0.0 9.5e-56 189.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Pmp3 PF01679.12 EGE00702.1 - 1.2e-23 82.5 4.5 1.3e-23 82.4 3.1 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator AflR PF08493.5 EGE00703.1 - 0.011 14.7 8.8 0.025 13.6 6.1 1.5 1 1 0 1 1 1 0 Aflatoxin regulatory protein APH PF01636.18 EGE00705.1 - 6.5e-12 45.6 0.0 2.8e-11 43.6 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGE00705.1 - 0.0013 17.4 0.0 0.0088 14.7 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EGE00705.1 - 0.026 13.6 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EGE00705.1 - 0.042 13.4 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Macro PF01661.16 EGE00707.1 - 1e-11 44.7 0.0 4.3e-06 26.6 0.0 2.6 2 1 1 3 3 3 2 Macro domain API5 PF05918.6 EGE00707.1 - 0.05 12.0 0.5 0.057 11.9 0.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CENP-X PF09415.5 EGE00708.1 - 8.2e-20 70.3 0.4 1.6e-19 69.5 0.3 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Paramyxo_ncap PF00973.14 EGE00708.1 - 0.86 8.2 4.7 1.2 7.7 3.2 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4242 PF14026.1 EGE00709.1 - 0.17 12.0 0.5 1.1 9.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4242) Mis12 PF05859.7 EGE00710.1 - 9.1e-45 152.0 0.0 1.5e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein Trans_reg_C PF00486.23 EGE00711.1 - 0.016 15.0 1.0 0.087 12.7 0.5 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal Oxidored_q1 PF00361.15 EGE00712.1 - 0.15 11.2 3.8 0.36 10.0 1.5 2.0 2 0 0 2 2 2 0 NADH-Ubiquinone/plastoquinone (complex I), various chains Claudin_2 PF13903.1 EGE00712.1 - 0.25 11.0 13.4 0.044 13.4 4.9 2.5 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF202 PF02656.10 EGE00712.1 - 6.5 7.0 6.8 2e+02 2.2 4.7 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) BCNT PF07572.7 EGE00713.1 - 8.2e-29 99.3 1.7 2.3e-28 97.9 1.1 1.8 1 0 0 1 1 1 1 Bucentaur or craniofacial development Pheromone PF08015.6 EGE00713.1 - 1.4 9.8 4.2 3.7 8.4 2.2 2.4 1 1 0 1 1 1 0 Fungal mating-type pheromone Acetyltransf_3 PF13302.1 EGE00714.1 - 1.6e-33 115.8 0.0 1.9e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGE00714.1 - 1.6e-05 24.8 0.1 0.00066 19.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE00714.1 - 0.001 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Methyltransf_3 PF01596.12 EGE00715.1 - 2.8e-34 117.9 0.0 4.2e-34 117.4 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EGE00715.1 - 2.1e-11 44.6 0.0 5.3e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGE00715.1 - 4.6e-11 42.6 0.0 6.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGE00715.1 - 1.3e-09 38.6 0.0 2.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE00715.1 - 9.4e-09 35.0 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE00715.1 - 9.9e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE00715.1 - 0.00031 19.9 0.0 0.00041 19.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGE00715.1 - 0.0066 16.9 0.0 0.015 15.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE00715.1 - 0.0091 16.4 0.0 0.054 13.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE00715.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EGE00715.1 - 0.019 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase GCD14 PF08704.5 EGE00715.1 - 0.029 13.8 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_15 PF09445.5 EGE00715.1 - 0.054 13.0 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PSP PF04046.11 EGE00716.1 - 0.22 10.9 1.8 0.62 9.5 1.3 1.7 1 0 0 1 1 1 0 PSP ADP_ribosyl_GH PF03747.9 EGE00716.1 - 1.7 8.3 12.1 0.76 9.4 3.1 2.1 1 1 1 2 2 2 0 ADP-ribosylglycohydrolase Spt20 PF12090.3 EGE00717.1 - 9e-12 44.7 0.3 9e-12 44.7 0.2 3.5 2 1 0 2 2 2 1 Spt20 family Birna_RdRp PF04197.7 EGE00717.1 - 2 6.3 15.4 2.7 5.9 10.6 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Med15 PF09606.5 EGE00717.1 - 5.4 5.0 74.6 0.0045 15.2 42.9 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serglycin PF04360.7 EGE00719.1 - 0.016 14.9 4.2 0.028 14.1 1.5 2.4 2 0 0 2 2 2 0 Serglycin Chordopox_A33R PF05966.7 EGE00721.1 - 0.15 10.8 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Hexapep PF00132.19 EGE00724.1 - 5.2e-07 28.8 2.6 0.0019 17.6 0.2 3.4 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EGE00724.1 - 0.00071 18.9 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGE00724.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fucokinase PF07959.7 EGE00724.1 - 0.084 11.4 0.1 0.13 10.8 0.1 1.2 1 0 0 1 1 1 0 L-fucokinase MMPL PF03176.10 EGE00725.1 - 0.079 11.6 2.7 1.7 7.3 0.1 2.2 2 0 0 2 2 2 0 MMPL family TRAP_beta PF05753.9 EGE00728.1 - 0.11 11.6 0.9 0.15 11.2 0.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) Mucin PF01456.12 EGE00728.1 - 1.7 8.4 11.3 1.9 8.2 7.7 1.2 1 1 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.4 EGE00728.1 - 5.2 5.2 6.8 5.3 5.2 4.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Gemini_V1 PF01524.12 EGE00729.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Geminivirus V1 protein Herpes_BLLF1 PF05109.8 EGE00729.1 - 0.4 8.5 4.9 0.52 8.2 3.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) ELO PF01151.13 EGE00731.1 - 1.6e-39 135.7 2.2 2e-39 135.4 1.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2072 PF09845.4 EGE00731.1 - 0.13 12.1 9.2 0.2 11.5 3.4 2.4 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) Fungal_trans PF04082.13 EGE00734.1 - 4.7e-23 81.3 0.0 8.8e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE00734.1 - 1.8e-09 37.3 11.0 3.1e-09 36.5 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TF_Zn_Ribbon PF08271.7 EGE00734.1 - 0.098 11.9 0.1 0.098 11.9 0.1 2.5 3 0 0 3 3 3 0 TFIIB zinc-binding TFIIA PF03153.8 EGE00734.1 - 4.4 7.1 30.1 2.7 7.7 7.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit G-alpha PF00503.15 EGE00734.1 - 7.4 5.1 16.8 0.027 13.1 1.8 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Aminotran_1_2 PF00155.16 EGE00735.1 - 5.8e-18 64.9 0.0 8.4e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGE00735.1 - 0.0061 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.2 EGE00735.1 - 0.041 12.4 0.0 0.17 10.4 0.0 1.8 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EGE00735.1 - 0.082 11.9 0.1 0.5 9.3 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.20 EGE00736.1 - 1.9e-53 181.2 0.0 2.7e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE00736.1 - 1.6e-39 135.5 0.0 2.5e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE00736.1 - 0.00088 18.3 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGE00736.1 - 0.0022 17.0 0.1 0.0065 15.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EGE00738.1 - 2.5e-70 236.5 0.4 3.2e-70 236.2 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE00738.1 - 9.6e-35 119.8 0.0 2.1e-34 118.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE00738.1 - 0.00015 20.8 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EGE00738.1 - 0.0041 16.4 0.0 0.014 14.6 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EGE00738.1 - 0.0085 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGE00738.1 - 0.089 12.5 0.1 0.31 10.7 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Methyltransf_8 PF05148.10 EGE00739.1 - 1e-57 195.3 0.5 4e-54 183.5 0.0 2.8 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EGE00739.1 - 1.1e-06 28.9 0.0 3.7e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE00739.1 - 0.013 15.8 0.0 1 9.7 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGE00739.1 - 0.051 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Proteasome PF00227.21 EGE00740.1 - 2e-56 190.2 0.1 2.7e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGE00740.1 - 8.5e-14 50.5 0.2 2.2e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EGE00740.1 - 0.019 14.6 0.1 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Spc97_Spc98 PF04130.8 EGE00741.1 - 3.4e-134 448.1 0.2 4.6e-134 447.6 0.2 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3346 PF11826.3 EGE00741.1 - 0.012 15.3 1.3 0.023 14.4 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) KH_1 PF00013.24 EGE00742.1 - 0.045 13.4 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 KH domain KH_3 PF13014.1 EGE00742.1 - 0.063 12.9 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 KH domain Methyltransf_23 PF13489.1 EGE00743.1 - 2.4e-13 50.1 0.0 3.3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE00743.1 - 7.9e-12 45.5 0.0 1.5e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE00743.1 - 3.7e-09 36.9 0.0 1e-08 35.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE00743.1 - 1.4e-08 34.4 0.0 3.3e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EGE00743.1 - 9.4e-07 29.3 0.0 4.7e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE00743.1 - 1.5e-05 25.2 0.0 5.4e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE00743.1 - 7.6e-05 22.7 0.0 0.00021 21.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGE00743.1 - 0.00022 20.3 0.0 0.00042 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EGE00743.1 - 0.00083 18.5 0.0 0.0049 15.9 0.0 2.1 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EGE00743.1 - 0.015 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 EGE00743.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EGE00743.1 - 0.049 13.6 0.1 0.2 11.6 0.0 1.9 2 1 0 3 3 3 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EGE00743.1 - 0.055 12.5 0.0 0.28 10.2 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.9 EGE00743.1 - 0.084 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB adh_short PF00106.20 EGE00744.1 - 8.7e-24 84.3 0.0 1.2e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE00744.1 - 4e-10 39.8 0.0 5.9e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE00744.1 - 1.7e-07 31.0 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGE00744.1 - 0.00033 20.7 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGE00744.1 - 0.00082 18.3 0.1 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGE00744.1 - 0.0024 17.3 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EGE00744.1 - 0.0029 16.6 0.1 0.0037 16.3 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EGE00744.1 - 0.063 12.9 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 EGE00744.1 - 0.1 11.8 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Erg28 PF03694.8 EGE00745.1 - 9.9e-40 135.0 2.2 1.2e-39 134.7 1.5 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF2417 PF10329.4 EGE00745.1 - 0.13 11.6 2.8 0.65 9.3 0.2 2.0 2 0 0 2 2 2 0 Region of unknown function (DUF2417) GalP_UDP_transf PF01087.17 EGE00746.1 - 7.1e-68 228.2 0.1 1.6e-66 223.8 0.0 2.2 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EGE00746.1 - 9.2e-57 191.2 0.2 2.1e-56 190.0 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain eIF3_subunit PF08597.5 EGE00748.1 - 0.041 13.4 0.2 0.041 13.4 0.1 2.3 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit DUF572 PF04502.8 EGE00748.1 - 0.061 12.5 3.7 0.099 11.8 2.6 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF572) NAPRTase PF04095.11 EGE00749.1 - 4e-52 176.9 0.1 2.2e-27 95.9 0.1 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family SNARE PF05739.14 EGE00751.1 - 9.8e-12 44.3 3.5 9.8e-12 44.3 2.4 2.1 2 1 1 3 3 3 1 SNARE domain Syntaxin PF00804.20 EGE00751.1 - 6.4e-07 29.4 7.8 3.3e-06 27.2 1.9 2.8 1 1 1 2 2 2 1 Syntaxin COG2 PF06148.6 EGE00751.1 - 0.0028 17.5 3.6 0.0086 15.9 0.0 2.5 2 2 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.16 EGE00751.1 - 0.0037 17.5 5.4 1.2 9.5 0.0 3.1 2 2 1 3 3 3 2 Spectrin repeat Rifin_STEVOR PF02009.11 EGE00751.1 - 0.0047 16.6 3.8 0.0072 16.0 2.4 1.5 1 1 0 1 1 1 1 Rifin/stevor family Activator-TraM PF11657.3 EGE00751.1 - 0.012 15.0 4.0 0.049 13.1 0.6 2.2 2 0 0 2 2 2 0 Transcriptional activator TraM PTA_PTB PF01515.14 EGE00751.1 - 0.036 13.1 1.7 0.054 12.5 1.2 1.3 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase DUF912 PF06024.7 EGE00751.1 - 0.055 13.5 0.4 0.055 13.5 0.3 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TSC22 PF01166.13 EGE00751.1 - 0.1 12.5 2.1 0.32 10.9 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF1664 PF07889.7 EGE00751.1 - 0.11 12.3 5.4 2.3 8.0 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) MCPsignal PF00015.16 EGE00751.1 - 0.14 11.7 12.3 0.19 11.2 4.7 2.6 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3904 PF13044.1 EGE00751.1 - 0.16 10.3 1.7 0.28 9.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3904) MT0933_antitox PF14013.1 EGE00751.1 - 0.18 11.9 1.0 0.53 10.4 0.1 2.3 2 1 0 2 2 2 0 MT0933-like antitoxin protein DUF3753 PF12575.3 EGE00751.1 - 0.21 11.4 3.4 0.45 10.3 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF607 PF04678.8 EGE00751.1 - 0.23 11.3 4.5 0.22 11.4 0.6 2.3 1 1 0 2 2 2 0 Protein of unknown function, DUF607 Baculo_11_kDa PF06143.6 EGE00751.1 - 0.26 10.6 5.4 0.99 8.8 3.7 2.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family PBP1_TM PF14812.1 EGE00751.1 - 0.34 11.2 4.4 0.12 12.7 0.3 2.4 1 1 2 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF805 PF05656.9 EGE00751.1 - 0.41 10.4 1.8 0.7 9.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) SP_C-Propep PF08999.5 EGE00751.1 - 1 8.9 4.6 1.8 8.1 3.2 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Tweety PF04906.8 EGE00751.1 - 1.3 7.3 5.5 0.51 8.6 1.8 1.7 1 1 1 2 2 2 0 Tweety HisKA_3 PF07730.8 EGE00751.1 - 2 8.8 7.0 3.3 8.1 0.1 3.6 2 1 1 4 4 4 0 Histidine kinase XH PF03469.9 EGE00751.1 - 2 8.0 5.7 1.1 8.9 1.4 2.1 1 1 0 2 2 2 0 XH domain Fib_alpha PF08702.5 EGE00751.1 - 9.9 6.2 11.8 28 4.8 0.3 3.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BolA PF01722.13 EGE00752.1 - 6.9e-19 67.5 0.0 8.1e-19 67.3 0.0 1.0 1 0 0 1 1 1 1 BolA-like protein RPA_C PF08784.6 EGE00752.1 - 0.014 15.7 0.0 0.014 15.7 0.0 1.1 1 0 0 1 1 1 0 Replication protein A C terminal Ribosomal_S5 PF00333.15 EGE00755.1 - 6.8e-29 99.4 3.5 2.4e-28 97.6 1.4 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EGE00755.1 - 6.8e-21 73.3 0.0 1.2e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF4263 PF14082.1 EGE00755.1 - 0.16 11.9 0.2 7 6.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4263) Bac_rhodopsin PF01036.13 EGE00757.1 - 1.4e-37 129.1 18.0 1.7e-37 128.9 12.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Glycos_transf_4 PF00953.16 EGE00757.1 - 0.22 11.3 13.5 0.04 13.7 4.3 2.6 2 1 0 2 2 2 0 Glycosyl transferase family 4 NfeD PF01957.13 EGE00757.1 - 0.25 11.4 8.5 1.3 9.1 1.7 3.0 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF3938 PF13074.1 EGE00757.1 - 0.77 9.6 5.2 0.3 10.9 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) tRNA-synt_1 PF00133.17 EGE00758.1 - 5e-165 549.9 0.0 6.6e-165 549.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGE00758.1 - 7.1e-22 77.8 0.4 1.5e-21 76.7 0.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGE00758.1 - 1.4e-21 76.6 0.1 7.5e-13 47.9 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EGE00758.1 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EGE00758.1 - 0.077 12.1 0.0 3.5 6.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.9 EGE00758.1 - 0.18 11.4 7.5 0.58 9.8 5.2 1.9 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS UPF0183 PF03676.9 EGE00759.1 - 3.2e-47 161.0 0.0 1.3e-31 109.5 0.0 3.9 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 EGE00760.1 - 5.4e-107 357.3 0.4 1.5e-106 355.8 0.3 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EGE00760.1 - 6.7e-07 29.5 0.6 6.7e-07 29.5 0.4 5.2 4 1 2 6 6 6 1 Kinesin-associated microtubule-binding zf-Apc11 PF12861.2 EGE00761.1 - 2.3e-44 149.1 9.5 4.1e-44 148.3 6.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGE00761.1 - 2e-31 107.8 9.1 3.7e-31 107.0 6.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGE00761.1 - 3.6e-08 33.0 13.0 1e-07 31.6 9.0 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGE00761.1 - 0.00038 20.4 9.4 0.0013 18.7 6.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE00761.1 - 0.0006 19.4 9.1 0.0014 18.2 6.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE00761.1 - 0.0056 16.3 11.0 0.052 13.2 7.7 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE00761.1 - 0.0086 15.7 11.4 0.026 14.2 7.9 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGE00761.1 - 0.14 12.0 7.6 0.46 10.3 5.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGE00761.1 - 0.24 11.0 10.4 2.5 7.7 5.3 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EGE00761.1 - 0.28 11.1 11.4 1.2 9.1 7.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 EGE00761.1 - 1.1 9.2 7.5 2.8 8.0 5.2 1.7 1 1 0 1 1 1 0 RING-like domain PHD PF00628.24 EGE00761.1 - 3.2 7.5 10.3 7.6 6.3 7.1 1.7 1 1 0 1 1 1 0 PHD-finger RINGv PF12906.2 EGE00761.1 - 7.9 6.6 8.6 19 5.3 6.0 1.7 1 1 0 1 1 1 0 RING-variant domain Rhodanese PF00581.15 EGE00762.1 - 1.6e-22 79.9 0.0 3.6e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain PIN_4 PF13638.1 EGE00763.1 - 0.00027 21.0 0.0 0.11 12.6 0.0 2.6 1 1 0 1 1 1 1 PIN domain NYN_YacP PF05991.6 EGE00763.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 YacP-like NYN domain 2OG-FeII_Oxy PF03171.15 EGE00764.1 - 0.082 13.2 0.1 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.23 EGE00765.1 - 0.0001 21.7 0.1 0.00029 20.2 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE00765.1 - 0.00026 20.8 0.1 0.00069 19.4 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RPEL PF02755.10 EGE00766.1 - 2e-24 84.2 3.2 5.9e-07 28.6 0.2 3.4 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.1 EGE00766.1 - 0.042 14.1 0.5 0.094 12.9 0.2 1.7 1 1 1 2 2 2 0 PPIC-type PPIASE domain Translin PF01997.11 EGE00767.1 - 7.6e-63 211.7 0.1 9e-63 211.4 0.0 1.1 1 0 0 1 1 1 1 Translin family DUF3375 PF11855.3 EGE00767.1 - 0.081 11.6 1.0 0.85 8.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) NPV_P10 PF05531.7 EGE00767.1 - 0.17 12.1 0.9 7.1 6.9 0.0 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mannosyl_trans PF05007.8 EGE00768.1 - 6e-79 265.3 10.7 9.5e-79 264.6 7.4 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EGE00768.1 - 3.2e-13 49.3 0.9 3.2e-13 49.3 0.6 2.3 2 1 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EGE00768.1 - 1.1e-05 25.0 4.2 1.1e-05 25.0 2.9 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2029) Ycf1 PF05758.7 EGE00770.1 - 0.56 7.8 1.6 1 6.9 1.1 1.3 1 0 0 1 1 1 0 Ycf1 Complex1_LYR_1 PF13232.1 EGE00771.1 - 1.1e-18 67.1 5.2 1.2e-18 67.0 3.6 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGE00771.1 - 3.6e-17 61.9 4.7 4.1e-17 61.7 3.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF2276 PF10040.4 EGE00771.1 - 0.067 13.3 0.1 0.072 13.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2276) Cir_N PF10197.4 EGE00771.1 - 0.14 12.2 2.1 0.23 11.5 1.4 1.3 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Catalase-rel PF06628.7 EGE00771.1 - 0.43 10.4 3.2 8 6.4 2.2 2.0 1 1 0 1 1 1 0 Catalase-related immune-responsive PBP1_TM PF14812.1 EGE00772.1 - 0.4 11.0 4.7 0.1 12.9 0.5 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HeLo PF14479.1 EGE00772.1 - 9.9 5.8 9.6 1.6e+02 1.8 6.7 2.2 1 1 0 1 1 1 0 Prion-inhibition and propagation DUF3498 PF12004.3 EGE00773.1 - 5.1 6.1 16.2 6.4 5.7 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) EGF_CA PF07645.10 EGE00774.1 - 0.83 9.6 5.6 1.8 8.6 3.9 1.5 1 0 0 1 1 1 0 Calcium-binding EGF domain hEGF PF12661.2 EGE00774.1 - 3.1 8.0 7.3 0.7 10.1 2.6 1.8 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.8 EGE00774.1 - 6.1 7.0 9.1 14 5.9 6.3 1.6 1 0 0 1 1 1 0 EGF-like domain ATP-sulfurylase PF01747.12 EGE00776.1 - 1.5e-87 292.4 0.0 2.1e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EGE00776.1 - 3.6e-57 192.4 0.0 5.5e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EGE00776.1 - 1.6e-49 167.4 0.0 2.6e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain PAPS_reduct PF01507.14 EGE00779.1 - 9.8e-43 145.9 0.0 1.4e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.2 EGE00780.1 - 1.5e-14 54.5 0.0 2.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGE00780.1 - 6.8e-13 49.5 0.3 3.3e-12 47.2 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGE00780.1 - 6.7e-08 32.4 0.2 1.1e-06 28.4 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGE00780.1 - 6.5e-06 26.4 0.0 2e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EGE00780.1 - 0.0025 17.0 0.0 0.062 12.4 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase DUF705 PF05152.7 EGE00780.1 - 0.021 13.8 0.3 0.029 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Radical_SAM PF04055.16 EGE00781.1 - 5.7e-13 49.3 0.0 1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily WD40 PF00400.27 EGE00782.1 - 1.1e-12 47.3 8.7 3.4e-06 26.7 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EGE00782.1 - 0.011 16.0 0.0 5.4 7.4 0.0 3.8 3 0 0 3 3 3 0 PQQ-like domain Gryzun-like PF12742.2 EGE00782.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Flavi_NS4A PF01350.12 EGE00783.1 - 0.024 14.1 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A TMEM51 PF15345.1 EGE00783.1 - 0.096 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DeoC PF01791.4 EGE00784.1 - 1.3e-43 148.9 4.4 1.6e-43 148.6 3.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 EGE00784.1 - 8.9e-05 21.5 1.4 0.00013 21.0 1.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EGE00784.1 - 0.018 14.3 0.4 0.035 13.3 0.3 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.13 EGE00784.1 - 0.1 11.4 2.9 0.14 10.9 0.8 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DUF2763 PF10961.3 EGE00785.1 - 2.7e-07 30.8 0.8 3.8e-07 30.4 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2763) GRP PF07172.6 EGE00785.1 - 0.0007 20.0 0.6 0.00089 19.6 0.4 1.2 1 0 0 1 1 1 1 Glycine rich protein family TP_methylase PF00590.15 EGE00786.1 - 2e-43 148.5 0.0 4e-43 147.5 0.0 1.5 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EGE00786.1 - 7.5e-13 48.6 0.0 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EGE00786.1 - 5.8e-08 31.9 0.0 0.00028 20.1 0.0 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal RRM_1 PF00076.17 EGE00787.1 - 1.9e-40 136.3 0.0 4.2e-17 61.5 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE00787.1 - 3.9e-31 106.8 0.0 4.7e-12 45.7 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE00787.1 - 1.3e-20 72.9 0.0 5.8e-06 26.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOR PF05036.8 EGE00787.1 - 0.0056 16.8 0.0 0.95 9.6 0.0 3.2 3 0 0 3 3 3 1 Sporulation related domain Limkain-b1 PF11608.3 EGE00787.1 - 0.0069 16.1 0.0 7.8 6.3 0.0 3.6 4 1 0 4 4 4 1 Limkain b1 ATP-grasp_2 PF08442.5 EGE00787.1 - 0.0072 15.7 0.0 0.058 12.7 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain PH PF00169.24 EGE00788.1 - 5.4e-10 39.4 0.0 1.2e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 PH domain CHAD PF05235.9 EGE00788.1 - 0.026 14.0 0.5 0.23 11.0 0.1 2.3 2 0 0 2 2 2 0 CHAD domain Prominin PF05478.6 EGE00788.1 - 0.15 9.5 0.2 0.21 9.0 0.1 1.1 1 0 0 1 1 1 0 Prominin Tim17 PF02466.14 EGE00789.1 - 2.7e-14 53.3 4.2 3.6e-14 52.8 2.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RPT PF13446.1 EGE00790.1 - 9e-49 162.7 2.0 3.2e-21 74.4 0.1 4.4 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.24 EGE00790.1 - 3.9e-10 39.3 0.0 7.3e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE00790.1 - 2.1e-06 27.3 0.1 3.5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 EGE00790.1 - 2.3e-05 24.0 0.0 5.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 PUB domain E7 PF00527.13 EGE00790.1 - 0.39 10.9 2.6 0.36 11.0 0.2 2.1 2 0 0 2 2 2 0 E7 protein, Early protein UCH PF00443.24 EGE00791.1 - 9.7e-34 116.6 0.1 1.2e-33 116.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MFS_1 PF07690.11 EGE00792.1 - 2.2e-19 69.4 54.8 9.1e-19 67.3 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CoA_trans PF01144.18 EGE00793.1 - 1.6e-104 347.8 1.9 4.8e-64 215.5 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF2370 PF10176.4 EGE00795.1 - 5.6e-85 284.3 0.0 1e-84 283.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 EGE00795.1 - 0.038 14.1 0.1 0.12 12.6 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Rb_C PF08934.5 EGE00796.1 - 0.0016 18.0 0.6 0.0037 16.8 0.4 1.6 1 0 0 1 1 1 1 Rb C-terminal domain WSC PF01822.14 EGE00797.1 - 7.1e-10 38.6 7.8 1.2e-09 37.9 5.4 1.4 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 EGE00797.1 - 0.25 10.6 2.7 0.66 9.3 1.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CDP-OH_P_transf PF01066.16 EGE00799.1 - 2.7e-12 46.8 0.7 4.6e-12 46.1 0.5 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.9 EGE00800.1 - 1.2e-42 145.0 0.1 1.2e-42 145.0 0.0 1.8 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 EGE00801.1 - 5e-43 146.6 0.1 8.2e-43 145.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGE00801.1 - 3e-16 59.1 0.1 5.8e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 EGE00801.1 - 0.0026 17.5 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain APH PF01636.18 EGE00802.1 - 3.3e-11 43.3 0.0 7.1e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RasGAP PF00616.14 EGE00803.1 - 2.2e-27 95.9 0.2 3e-17 62.9 0.0 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase DNA_methylase PF00145.12 EGE00804.1 - 1.2e-32 113.4 0.0 2.2e-32 112.5 0.0 1.5 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EGE00804.1 - 2.4e-08 33.7 0.1 0.00045 19.9 0.1 2.8 3 0 0 3 3 3 2 BAH domain DNMT1-RFD PF12047.3 EGE00804.1 - 0.01 15.5 0.1 0.055 13.1 0.0 2.2 3 0 0 3 3 3 0 Cytosine specific DNA methyltransferase replication foci domain WD40 PF00400.27 EGE00805.1 - 1e-12 47.4 1.2 0.00044 20.0 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EGE00805.1 - 0.032 12.3 0.1 0.048 11.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Hrs_helical PF12210.3 EGE00806.1 - 0.039 14.2 0.1 0.6 10.3 0.0 2.4 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate COQ9 PF08511.6 EGE00807.1 - 8e-24 82.9 0.4 2e-23 81.6 0.1 1.8 2 0 0 2 2 2 1 COQ9 PalH PF08733.5 EGE00808.1 - 0.074 11.8 3.5 0.1 11.4 2.4 1.3 1 0 0 1 1 1 0 PalH/RIM21 AA_permease_2 PF13520.1 EGE00809.1 - 4.9e-52 176.8 49.9 6e-52 176.6 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE00809.1 - 2.7e-22 78.7 42.8 3.8e-22 78.2 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease FmdA_AmdA PF03069.10 EGE00810.1 - 3e-58 197.2 0.0 3.1e-31 108.3 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family Cyclin PF08613.6 EGE00811.1 - 1.6e-31 109.6 1.6 1.1e-17 64.8 0.4 4.1 4 2 1 5 5 5 2 Cyclin Proteasome PF00227.21 EGE00812.1 - 5.5e-46 156.2 0.3 6.3e-46 156.0 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit RabGAP-TBC PF00566.13 EGE00813.1 - 1.3e-27 96.6 0.0 2.7e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Telomerase_RBD PF12009.3 EGE00814.1 - 5.1e-39 133.2 0.0 1.1e-38 132.1 0.0 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EGE00814.1 - 3.6e-13 49.3 0.0 2.5e-12 46.5 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGEF PF00621.15 EGE00815.1 - 1.8e-37 128.9 0.0 4.2e-37 127.7 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 EGE00815.1 - 4.6e-13 49.2 0.3 2e-12 47.1 0.2 2.1 1 1 0 1 1 1 1 BAR domain Lipoprotein_7 PF01540.11 EGE00815.1 - 0.28 10.1 1.1 7.6 5.4 0.0 2.2 2 0 0 2 2 2 0 Adhesin lipoprotein Peptidase_C48 PF02902.14 EGE00816.1 - 1e-13 51.4 0.6 4.4e-13 49.3 0.4 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Alg14 PF08660.6 EGE00816.1 - 0.018 15.0 0.1 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like PrpF PF04303.8 EGE00817.1 - 1.1e-106 356.7 0.2 1.3e-106 356.5 0.1 1.0 1 0 0 1 1 1 1 PrpF protein tRNA-synt_1d PF00750.14 EGE00818.1 - 7.4e-70 235.5 0.2 1.7e-69 234.3 0.2 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EGE00818.1 - 4e-28 97.7 0.2 2.4e-27 95.2 0.0 2.3 2 0 0 2 2 2 1 DALR anticodon binding domain RRM_1 PF00076.17 EGE00821.1 - 8.1e-05 22.1 0.0 8.1e-05 22.1 0.0 2.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE00821.1 - 0.00019 21.3 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE00821.1 - 0.0049 16.6 0.6 0.017 14.9 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMS1 PF14617.1 EGE00822.1 - 1.7e-75 253.3 1.6 3.2e-75 252.4 1.1 1.4 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EGE00822.1 - 0.0005 19.5 0.0 0.00063 19.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase CENP-T PF15511.1 EGE00823.1 - 4.7e-79 266.5 16.3 6e-79 266.2 11.3 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EGE00823.1 - 3.6e-08 33.4 0.1 6.4e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EGE00823.1 - 1.5e-05 25.0 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGE00823.1 - 0.0001 22.3 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-X PF09415.5 EGE00823.1 - 0.051 13.4 0.7 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 CENP-S associating Centromere protein X SURF1 PF02104.10 EGE00824.1 - 4e-66 222.8 0.0 5.1e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.15 EGE00825.1 - 1.5e-09 37.7 0.0 3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF2076 PF09849.4 EGE00826.1 - 1.2e-07 32.1 10.8 1.4e-07 31.8 7.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EGE00826.1 - 2.4e-05 24.1 2.5 3.7e-05 23.5 1.7 1.3 1 0 0 1 1 1 1 CHCH domain Bindin PF02084.10 EGE00826.1 - 0.18 11.8 3.9 0.24 11.4 2.7 1.2 1 0 0 1 1 1 0 Bindin TFIIA PF03153.8 EGE00826.1 - 2.6 7.8 4.8 3.2 7.5 3.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sas10_Utp3 PF04000.10 EGE00827.1 - 2.9e-18 65.8 1.2 2.9e-18 65.8 0.9 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Roughex PF06020.6 EGE00827.1 - 0.021 13.5 6.7 0.028 13.1 4.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein ApbA_C PF08546.6 EGE00828.1 - 6.6e-31 106.9 0.1 1e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EGE00828.1 - 1.2e-24 86.4 0.0 2.2e-23 82.3 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EGE00828.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 ThiF family Coq4 PF05019.8 EGE00829.1 - 8.4e-98 325.7 0.0 9.8e-98 325.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.15 EGE00830.1 - 1.7e-34 118.0 11.4 2e-34 117.7 7.9 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 EGE00830.1 - 0.038 14.2 0.8 0.054 13.7 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) Sec2p PF06428.6 EGE00831.1 - 1.7e-27 95.2 16.0 1.2e-26 92.5 11.4 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p ScpA_ScpB PF02616.9 EGE00831.1 - 0.55 9.7 9.6 1.1 8.8 6.6 1.4 1 0 0 1 1 1 0 ScpA/B protein IncA PF04156.9 EGE00831.1 - 0.61 9.6 13.6 1.2 8.6 9.4 1.5 1 0 0 1 1 1 0 IncA protein DUF3584 PF12128.3 EGE00831.1 - 1.1 6.4 17.9 1.6 5.9 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 EGE00831.1 - 2.7 8.0 7.7 5.5 7.0 4.7 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PRP21_like_P PF12230.3 EGE00832.1 - 4e-58 196.6 12.9 8.1e-56 189.0 8.9 2.4 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EGE00832.1 - 5.4e-36 122.0 2.1 2.7e-17 62.1 0.0 2.3 2 0 0 2 2 2 2 Surp module UPF0547 PF10571.4 EGE00832.1 - 0.56 9.9 3.9 0.12 12.0 0.3 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 PMT PF02366.13 EGE00833.1 - 7.3e-73 244.9 16.0 7.3e-73 244.9 11.1 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGE00833.1 - 7.3e-54 182.2 0.0 1.1e-53 181.6 0.0 1.3 1 0 0 1 1 1 1 MIR domain Arteri_Gl PF00951.13 EGE00833.1 - 0.0078 15.8 2.2 0.017 14.7 1.5 1.5 1 0 0 1 1 1 1 Arterivirus GL envelope glycoprotein zf-DHHC PF01529.15 EGE00834.1 - 4.5e-34 117.3 7.9 4.5e-34 117.3 5.5 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.12 EGE00834.1 - 0.13 11.7 5.9 0.11 11.9 0.2 2.1 2 0 0 2 2 2 0 Yip1 domain SET PF00856.23 EGE00835.1 - 5.7e-17 62.5 0.2 5.7e-17 62.5 0.2 2.8 3 1 0 3 3 3 1 SET domain DLH PF01738.13 EGE00836.1 - 1.9e-13 50.2 0.0 2.6e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGE00836.1 - 5.7e-05 22.9 0.0 7.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE00836.1 - 0.06 13.2 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE00836.1 - 0.066 12.7 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1754 PF08555.5 EGE00840.1 - 1.9e-15 57.2 18.8 1.9e-15 57.2 13.1 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF3827 PF12877.2 EGE00840.1 - 0.025 12.6 9.4 0.029 12.4 6.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SPX PF03105.14 EGE00840.1 - 0.22 11.2 8.2 0.26 11.0 5.7 1.0 1 0 0 1 1 1 0 SPX domain Spore_coat_CotO PF14153.1 EGE00840.1 - 0.23 10.9 12.9 0.28 10.6 8.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO HSP70 PF00012.15 EGE00840.1 - 0.23 9.2 10.9 0.28 9.0 7.5 1.0 1 0 0 1 1 1 0 Hsp70 protein CDC27 PF09507.5 EGE00840.1 - 0.29 10.3 16.4 0.32 10.1 11.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NDUF_B4 PF07225.7 EGE00840.1 - 0.33 10.7 6.2 0.079 12.7 1.6 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DNA_pol_viral_N PF00242.12 EGE00840.1 - 1.4 7.8 6.6 1.6 7.6 4.6 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PTPA PF03095.10 EGE00841.1 - 8.4e-23 80.9 0.3 2.7e-22 79.3 0.2 1.7 1 1 1 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein DUF202 PF02656.10 EGE00843.1 - 2.4e-06 27.6 0.1 2.4e-06 27.6 0.1 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF202) YbgS PF13985.1 EGE00843.1 - 0.02 14.8 1.1 0.052 13.4 0.7 1.7 1 0 0 1 1 1 0 YbgS-like protein DUF4187 PF13821.1 EGE00846.1 - 3.4e-22 77.7 0.0 8e-22 76.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 EGE00846.1 - 3.7e-09 37.1 3.8 3.7e-09 37.1 2.6 2.1 1 1 2 3 3 3 1 Arsenite-resistance protein 2 CDC27 PF09507.5 EGE00848.1 - 2 7.5 10.6 2.2 7.4 7.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Kinesin PF00225.18 EGE00849.1 - 7.8e-112 373.2 0.0 1.2e-111 372.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EGE00849.1 - 1.9e-43 147.4 0.0 3.7e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 EGE00849.1 - 3.2e-07 30.2 1.7 4.8e-07 29.6 0.2 2.1 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.24 EGE00849.1 - 4.2e-06 26.8 0.0 3.3e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 PH domain FHA PF00498.21 EGE00849.1 - 0.00034 20.6 0.3 0.0036 17.3 0.0 2.8 3 0 0 3 3 3 1 FHA domain 3-dmu-9_3-mt PF06983.8 EGE00850.1 - 2.7e-39 134.0 0.0 3.8e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase DSX_dimer PF08828.5 EGE00850.1 - 0.0089 15.5 0.1 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Doublesex dimerisation domain Phosphodiest PF01663.17 EGE00851.1 - 1.5e-84 284.4 0.1 2.4e-84 283.7 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGE00851.1 - 0.00042 19.5 0.0 0.21 10.7 0.0 2.3 1 1 1 2 2 2 2 Sulfatase PglZ PF08665.7 EGE00851.1 - 0.0014 18.3 0.1 0.06 13.0 0.0 2.6 3 0 0 3 3 3 1 PglZ domain DUF3753 PF12575.3 EGE00851.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) HNH_2 PF13391.1 EGE00852.1 - 5.2e-09 35.7 0.0 2.9e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease ATP-synt_E PF05680.7 EGE00852.1 - 1.7 8.6 5.3 5.4 7.0 0.9 3.3 4 0 0 4 4 4 0 ATP synthase E chain PHP PF02811.14 EGE00853.1 - 2.4e-06 27.4 0.0 2.2e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 PHP domain Herpes_US9 PF06072.6 EGE00856.1 - 0.0098 15.7 1.0 0.018 14.8 0.7 1.3 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 DUF3723 PF12520.3 EGE00857.1 - 1.1e-19 70.3 0.1 2.3e-19 69.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3723) GIDA_assoc_3 PF13932.1 EGE00857.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.8 1 1 0 1 1 1 0 GidA associated domain 3 APH PF01636.18 EGE00858.1 - 5.4e-05 23.0 0.0 6.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family HipA_N PF07805.7 EGE00858.1 - 0.0016 18.6 0.0 0.66 10.2 0.0 2.2 1 1 1 2 2 2 2 HipA-like N-terminal domain Fructosamin_kin PF03881.9 EGE00858.1 - 0.008 15.1 0.0 0.0099 14.8 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase Pkinase PF00069.20 EGE00858.1 - 0.15 11.1 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Inhibitor_I34 PF10466.4 EGE00859.1 - 0.091 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopepsin inhibitor I34 Peroxin-3 PF04882.7 EGE00860.1 - 3.6e-07 29.2 0.0 3.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 Pkinase PF00069.20 EGE00861.1 - 0.0013 17.9 0.0 0.0015 17.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.4 EGE00861.1 - 0.031 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RTC4 PF14474.1 EGE00865.1 - 2.7e-21 75.8 0.0 8e-21 74.2 0.0 1.7 1 1 0 1 1 1 1 RTC4-like domain zf-Di19 PF05605.7 EGE00865.1 - 0.17 12.0 2.9 0.17 12.0 0.0 2.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding AMP-binding PF00501.23 EGE00866.1 - 1.4e-65 221.3 0.0 3.4e-65 220.0 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE00866.1 - 0.01 16.7 0.0 0.022 15.7 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain LVIVD PF08309.6 EGE00867.1 - 2.7e-05 23.0 0.2 0.028 13.4 0.0 3.4 3 0 0 3 3 3 3 LVIVD repeat Methyltransf_16 PF10294.4 EGE00868.1 - 2.3e-09 36.9 0.2 4.6e-05 22.9 0.0 2.3 2 1 0 2 2 2 2 Putative methyltransferase BAF1_ABF1 PF04684.8 EGE00868.1 - 7.1 5.3 7.2 10 4.8 5.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MIF4G PF02854.14 EGE00869.1 - 1.2e-52 178.3 0.0 1.9e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EGE00869.1 - 2.1e-23 81.9 1.9 5.6e-23 80.6 1.3 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 CENP-T PF15511.1 EGE00870.1 - 2.8 7.0 8.7 3.1 6.9 6.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TB2_DP1_HVA22 PF03134.14 EGE00871.1 - 1.4e-27 95.2 8.4 2e-27 94.7 5.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family F-box-like PF12937.2 EGE00872.1 - 8.3e-05 22.2 0.1 0.00019 21.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE00872.1 - 0.0008 19.0 0.3 0.0021 17.6 0.2 1.7 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 EGE00872.1 - 0.026 14.5 0.2 0.071 13.0 0.1 1.7 1 0 0 1 1 1 0 PRANC domain Peptidase_S32 PF05579.8 EGE00873.1 - 0.0029 16.6 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Trypsin_2 PF13365.1 EGE00873.1 - 0.016 15.1 0.0 0.086 12.8 0.0 2.1 1 1 0 1 1 1 0 Trypsin-like peptidase domain LisH PF08513.6 EGE00877.1 - 7.3e-05 22.3 0.1 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 LisH TRAPP PF04051.11 EGE00879.1 - 3.2e-37 127.3 0.0 3.9e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.27 EGE00880.1 - 9.4e-53 174.3 11.0 7.8e-08 31.9 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EGE00880.1 - 0.00018 21.3 0.0 1.8 8.2 0.0 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EGE00880.1 - 0.022 13.5 4.9 1 7.9 0.4 2.7 1 1 1 2 2 2 0 Nup133 N terminal like LCD1 PF09798.4 EGE00881.1 - 0.15 10.0 0.1 0.2 9.6 0.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Glyco_hydro_47 PF01532.15 EGE00882.1 - 1.1e-132 442.8 0.0 1.3e-132 442.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DNA_pol_B_exo2 PF10108.4 EGE00882.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Pribosyltran PF00156.22 EGE00883.1 - 3.3e-15 55.9 0.0 4.9e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGE00883.1 - 0.014 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Glyco_hydro_42M PF08532.5 EGE00884.1 - 0.037 13.1 0.0 3.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain DUF4350 PF14258.1 EGE00884.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Macoilin PF09726.4 EGE00886.1 - 0.018 13.3 5.9 0.022 13.0 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein SlyX PF04102.7 EGE00886.1 - 0.039 14.3 0.6 0.42 11.0 0.2 2.6 2 0 0 2 2 2 0 SlyX RAP1 PF07218.6 EGE00886.1 - 7.7 4.4 8.2 10 4.0 5.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HAD_2 PF13419.1 EGE00887.1 - 2.6e-15 57.0 0.0 5.1e-15 56.1 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGE00887.1 - 0.00094 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Ribosomal_L18p PF00861.17 EGE00888.1 - 9.9e-44 148.3 0.3 2e-43 147.4 0.1 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EGE00888.1 - 1e-32 112.5 2.6 1e-32 112.5 1.8 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF3135 PF11333.3 EGE00889.1 - 0.015 15.4 0.1 0.11 12.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) LRR_6 PF13516.1 EGE00889.1 - 0.39 10.9 9.1 29 5.1 0.0 6.9 9 0 0 9 9 9 0 Leucine Rich repeat LRR_7 PF13504.1 EGE00889.1 - 1.1 9.7 5.6 77 4.1 0.0 5.8 7 0 0 7 7 7 0 Leucine rich repeat ABC_membrane_2 PF06472.10 EGE00890.1 - 2.5e-109 364.7 1.4 3.6e-109 364.2 1.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGE00890.1 - 2.2e-18 66.9 0.0 3.9e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGE00890.1 - 0.00013 22.0 0.0 0.00033 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGE00890.1 - 0.0052 16.2 0.0 0.02 14.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EGE00890.1 - 0.011 16.0 0.0 0.029 14.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGE00890.1 - 0.024 14.5 0.1 0.088 12.7 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.14 EGE00890.1 - 0.029 13.5 0.0 0.091 11.9 0.0 1.8 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EGE00890.1 - 0.089 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EGE00890.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase p450 PF00067.17 EGE00891.1 - 1.6e-65 221.4 0.0 2.1e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.18 EGE00893.1 - 2.5e-14 53.6 0.1 5.6e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGE00893.1 - 0.0013 17.9 0.1 0.081 12.0 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Choline_kinase PF01633.15 EGE00893.1 - 0.0024 17.4 0.1 0.0042 16.6 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EGE00893.1 - 0.017 14.4 0.9 0.18 11.1 0.0 2.6 3 0 0 3 3 3 0 RIO1 family DSHCT PF08148.7 EGE00893.1 - 0.11 11.7 0.0 7.5 5.7 0.0 2.8 3 0 0 3 3 3 0 DSHCT (NUC185) domain Phosphorylase PF00343.15 EGE00894.1 - 5.5e-141 470.8 0.2 6.8e-141 470.5 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase CBM-like PF14683.1 EGE00896.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain III Suc_Fer-like PF06999.7 EGE00897.1 - 3.3e-33 115.6 0.0 3.4e-32 112.3 0.0 2.1 1 1 0 1 1 1 1 Sucrase/ferredoxin-like APH PF01636.18 EGE00899.1 - 3.6e-12 46.5 0.0 5.1e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE00899.1 - 0.0003 20.4 0.0 0.00065 19.3 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EGE00899.1 - 0.0031 16.5 0.0 0.0056 15.6 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase Exo_endo_phos_2 PF14529.1 EGE00900.1 - 3.8e-12 45.8 0.1 2.2e-11 43.3 0.0 2.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EGE00900.1 - 0.00045 20.2 0.0 0.00068 19.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family eIF3g PF12353.3 EGE00900.1 - 2.5 8.0 8.3 6.3 6.7 2.2 3.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G CHAT PF12770.2 EGE00902.1 - 1.9e-29 102.7 0.0 2.8e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 CHAT domain Raptor_N PF14538.1 EGE00902.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain TPR_12 PF13424.1 EGE00904.1 - 2e-08 34.0 4.8 9.5e-05 22.2 0.2 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGE00904.1 - 1.3e-05 24.7 0.3 1.6 8.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGE00904.1 - 0.0029 18.2 5.5 0.011 16.4 2.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGE00904.1 - 0.0055 16.2 0.2 7.2 6.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EGE00904.1 - 0.0064 16.8 4.6 0.53 10.8 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGE00904.1 - 0.0076 16.5 3.7 0.039 14.2 1.4 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGE00904.1 - 0.074 13.0 5.4 3.5 7.6 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGE00904.1 - 0.17 12.6 5.7 5.7 7.8 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGE00904.1 - 0.29 11.0 3.7 26 4.9 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat T2SJ PF11612.3 EGE00905.1 - 0.0059 16.3 0.2 0.01 15.6 0.0 1.5 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein J APH PF01636.18 EGE00906.1 - 3.5e-14 53.1 0.3 4.5e-14 52.7 0.2 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE00906.1 - 2.5e-05 23.9 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EGE00906.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Ank_2 PF12796.2 EGE00907.1 - 4.1e-114 373.1 11.6 3.6e-22 78.5 0.0 6.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE00907.1 - 3.3e-69 228.1 6.5 5.3e-15 55.4 0.0 6.8 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.25 EGE00907.1 - 6.4e-67 218.2 8.0 2.7e-07 30.0 0.0 10.2 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.1 EGE00907.1 - 1.5e-63 204.3 2.7 6.6e-06 25.8 0.0 10.1 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.1 EGE00907.1 - 7.9e-44 146.7 6.3 7.6e-11 41.8 0.0 8.0 4 2 4 8 8 8 7 Ankyrin repeats (many copies) F-box-like PF12937.2 EGE00907.1 - 2.6e-05 23.8 0.1 4.3e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like TPR_20 PF14561.1 EGE00907.1 - 0.0035 17.4 0.0 0.62 10.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat F-box PF00646.28 EGE00907.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 F-box domain Myb_DNA-binding PF00249.26 EGE00908.1 - 0.014 15.4 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain PBP1_TM PF14812.1 EGE00908.1 - 0.96 9.7 8.6 2.3 8.5 6.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4140 PF13600.1 EGE00909.1 - 0.11 12.9 0.4 0.11 12.9 0.3 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 EGE00909.1 - 0.51 9.8 9.6 0.12 11.9 0.2 2.1 2 0 0 2 2 2 0 IncA protein Nucleo_P87 PF07267.6 EGE00909.1 - 0.68 8.5 8.4 1 8.0 5.8 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ADIP PF11559.3 EGE00909.1 - 1.2 9.0 8.8 7.4 6.4 0.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1658 PF07871.6 EGE00911.1 - 0.0032 16.9 0.1 8.5 6.1 0.0 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF1658) Dus PF01207.12 EGE00912.1 - 1.3e-41 142.4 0.0 4.3e-29 101.3 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EGE00912.1 - 4.1e-05 23.1 2.8 0.05 13.3 0.3 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_5 PF13854.1 EGE00913.1 - 3.1e-28 97.2 0.1 2e-06 27.6 0.0 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 EGE00913.1 - 7.4e-26 89.6 6.3 4.5e-07 29.5 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EGE00913.1 - 3.6e-25 87.0 1.7 1.3e-05 25.0 0.0 5.2 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EGE00913.1 - 5.1e-25 86.9 11.5 1.2e-08 34.9 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EGE00913.1 - 3.9e-23 80.2 1.4 3.5e-07 29.7 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 EGE00913.1 - 9.4e-21 73.1 2.5 5.5e-05 22.6 0.1 5.0 5 0 0 5 5 5 4 Kelch motif BTB PF00651.26 EGE00913.1 - 6.1e-08 32.6 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Choline_kinase PF01633.15 EGE00914.1 - 1.7e-06 27.7 1.2 2.7e-06 27.1 0.8 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EGE00914.1 - 3e-06 27.1 0.1 3.9e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGE00914.1 - 0.0014 17.8 0.0 0.0017 17.5 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EGE00914.1 - 0.064 11.8 0.0 0.079 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) WD40 PF00400.27 EGE00915.1 - 2.7e-22 77.7 16.8 2.1e-06 27.3 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EGE00915.1 - 0.0002 21.1 0.4 0.011 15.4 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRS1 PF04939.7 EGE00916.1 - 1.2e-32 112.7 13.9 1.4e-32 112.4 9.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.22 EGE00917.1 - 1.4e-27 96.1 0.0 2.4e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.16 EGE00919.1 - 8e-58 191.6 5.0 3.5e-12 45.6 0.0 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGE00919.1 - 2.8e-32 111.4 0.1 4.2e-15 56.1 0.0 3.2 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGE00919.1 - 1.8e-11 43.9 0.1 0.0003 20.7 0.0 3.3 2 1 1 3 3 3 2 Prenyltransferase-like Peptidase_S8 PF00082.17 EGE00924.1 - 3.9e-49 167.2 2.0 4.7e-49 167.0 1.4 1.1 1 0 0 1 1 1 1 Subtilase family DUF221 PF02714.10 EGE00926.1 - 2.9e-71 240.0 24.6 6.7e-46 156.6 11.2 3.1 1 1 1 2 2 2 2 Domain of unknown function DUF221 DUF3981 PF13139.1 EGE00926.1 - 0.02 14.8 1.5 0.055 13.4 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3981) Mito_morph_reg PF14972.1 EGE00926.1 - 0.12 11.7 0.3 0.24 10.8 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator MFS_1 PF07690.11 EGE00927.1 - 6.9e-09 34.8 7.1 0.00086 18.1 6.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4282 PF14110.1 EGE00927.1 - 0.02 15.0 7.4 0.21 11.8 3.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) Mem_trans PF03547.13 EGE00927.1 - 0.034 12.4 0.1 0.037 12.3 0.1 1.1 1 0 0 1 1 1 0 Membrane transport protein Virul_fac_BrkB PF03631.10 EGE00927.1 - 0.086 12.1 5.4 0.052 12.9 1.0 1.9 1 1 1 2 2 2 0 Virulence factor BrkB Oxidored_q3 PF00499.15 EGE00927.1 - 0.52 10.0 6.2 0.73 9.5 4.3 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 MFS_2 PF13347.1 EGE00927.1 - 3.9 5.7 12.3 6.1 5.1 8.6 1.3 1 1 0 1 1 1 0 MFS/sugar transport protein Bac_GDH PF05088.7 EGE00928.1 - 1.3e-14 52.7 0.1 1.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EGE00928.1 - 0.023 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF3546 PF12066.3 EGE00929.1 - 8.5e-25 86.9 0.2 8.5e-25 86.9 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) HATPase_c PF02518.21 EGE00931.1 - 1.6e-07 31.0 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RSN1_TM PF13967.1 EGE00936.1 - 8.7e-33 113.1 0.5 9.5e-33 112.9 0.3 1.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport HD PF01966.17 EGE00938.1 - 0.0036 17.3 0.1 0.007 16.3 0.0 1.5 1 1 0 1 1 1 1 HD domain zf-H2C2_2 PF13465.1 EGE00939.1 - 3.2e-08 33.4 11.7 4.6e-06 26.6 1.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGE00939.1 - 1.2e-05 25.2 18.7 8.7e-05 22.5 4.3 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE00939.1 - 0.00052 20.1 16.8 0.0085 16.3 4.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 EGE00939.1 - 0.0012 18.9 7.4 0.002 18.2 4.9 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EGE00939.1 - 0.023 14.8 9.8 0.028 14.5 0.7 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EGE00939.1 - 0.069 12.9 0.8 0.069 12.9 0.6 2.7 3 0 0 3 3 3 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 EGE00939.1 - 0.071 12.9 1.4 0.12 12.1 1.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-met PF12874.2 EGE00939.1 - 0.12 12.5 5.3 0.86 9.8 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EGE00939.1 - 1.5 8.6 8.4 4.3 7.1 0.7 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type QCR10 PF09796.4 EGE00940.1 - 5.6e-25 86.7 0.1 6.8e-25 86.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Glyco_tran_28_C PF04101.11 EGE00941.1 - 0.075 12.6 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Helicase_C PF00271.26 EGE00942.1 - 2e-13 50.0 0.0 3.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain APH PF01636.18 EGE00943.1 - 8.6e-05 22.3 0.4 0.0001 22.1 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGE00943.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase