# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- MIS13 PF08202.11 EGD83718.1 - 8.3e-44 150.1 4.3 8.3e-44 150.1 4.3 2.1 2 1 0 2 2 2 1 Mis12-Mtw1 protein family DivIC PF04977.15 EGD83718.1 - 0.018 14.8 0.1 0.054 13.3 0.1 1.8 1 0 0 1 1 1 0 Septum formation initiator pPIWI_RE_Y PF18156.1 EGD83718.1 - 0.056 13.9 0.1 1.7 9.1 0.0 2.9 3 0 0 3 3 3 0 pPIWI_RE three-gene island domain Y RPN7 PF10602.9 EGD83719.1 - 8.5e-55 185.1 0.4 1.6e-54 184.2 0.4 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGD83719.1 - 4.7e-12 46.3 0.0 9.9e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 EGD83719.1 - 0.11 12.5 2.0 0.51 10.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 EGD83720.2 - 3.5e-33 115.3 0.0 4.4e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II TetR_C_14 PF17754.1 EGD83720.2 - 0.18 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 MftR C-terminal domain Sugar_tr PF00083.24 EGD83723.2 - 2.3e-32 112.4 26.1 9.9e-21 74.1 8.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGD83723.2 - 1.1e-18 67.3 63.9 7.4e-18 64.6 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4305 PF14146.6 EGD83723.2 - 9.9 6.5 8.4 4.5 7.5 1.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) PEX11 PF05648.14 EGD83724.1 - 2.7e-68 229.8 0.1 3e-68 229.6 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Amidase PF01425.21 EGD83725.1 - 3.1e-68 230.8 0.0 1.7e-66 225.1 0.0 2.0 1 1 0 1 1 1 1 Amidase ARID PF01388.21 EGD83726.1 - 7.2e-12 45.8 0.0 9.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF3328 PF11807.8 EGD83727.1 - 0.0037 17.1 0.0 0.0061 16.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RFX_DNA_binding PF02257.15 EGD83727.1 - 0.11 13.2 0.0 0.25 12.0 0.0 1.6 1 0 0 1 1 1 0 RFX DNA-binding domain DJ-1_PfpI PF01965.24 EGD83728.1 - 6.8e-16 58.5 0.0 8.1e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GPI-anchored PF10342.9 EGD83729.2 - 0.00025 21.7 0.3 0.0038 17.9 0.0 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ArfGap PF01412.18 EGD83730.1 - 1.3e-39 134.9 2.5 2e-39 134.3 2.5 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.18 EGD83731.1 - 6.2e-50 168.3 0.2 9e-50 167.8 0.2 1.2 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 EGD83731.1 - 0.047 13.4 0.3 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 EGD83731.1 - 0.11 12.7 1.4 0.48 10.7 1.4 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF1771 PF08590.10 EGD83732.1 - 2.1e-11 44.0 4.9 4.9e-11 42.8 4.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 EGD83732.1 - 1.7e-10 40.4 1.1 8e-08 31.8 0.0 3.3 3 0 0 3 3 3 2 CUE domain Smr PF01713.21 EGD83732.1 - 1.2e-05 25.5 0.1 3.6e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 Smr domain EF_assoc_2 PF08356.12 EGD83734.1 - 6.2e-35 119.1 0.0 1.2e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 EGD83734.1 - 2.1e-30 104.1 0.3 3.6e-30 103.4 0.3 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EGD83734.1 - 1.1e-23 83.6 0.0 1.9e-13 50.4 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGD83734.1 - 3.8e-13 49.7 0.0 2.4e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGD83734.1 - 2e-09 37.5 0.0 3.9e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 EGD83734.1 - 2.3e-07 29.9 3.9 0.0057 16.1 0.1 3.0 3 0 0 3 3 2 2 EF hand EF-hand_6 PF13405.6 EGD83734.1 - 6.2e-07 28.9 3.3 0.02 14.8 0.0 2.9 3 0 0 3 3 2 2 EF-hand domain EF-hand_7 PF13499.6 EGD83734.1 - 7.9e-07 29.4 1.2 0.0026 18.2 0.2 3.0 3 0 0 3 3 2 2 EF-hand domain pair AAA_16 PF13191.6 EGD83734.1 - 1.3e-05 25.7 0.1 0.043 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGD83734.1 - 2e-05 24.2 0.1 0.016 14.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_10 PF14788.6 EGD83734.1 - 2.8e-05 23.9 2.6 0.0048 16.7 0.3 2.4 2 0 0 2 2 2 1 EF hand Dynamin_N PF00350.23 EGD83734.1 - 0.00013 22.1 0.8 1 9.4 0.0 3.3 4 0 0 4 4 3 2 Dynamin family AAA_22 PF13401.6 EGD83734.1 - 0.00032 21.0 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGD83734.1 - 0.0011 18.9 0.1 1.9 8.4 0.1 3.3 3 0 0 3 3 3 1 RsgA GTPase Viral_helicase1 PF01443.18 EGD83734.1 - 0.0025 17.6 0.1 0.11 12.3 0.0 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 EGD83734.1 - 0.0052 17.0 0.0 3.1 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGD83734.1 - 0.0057 17.2 0.2 2 8.9 0.2 2.7 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 EGD83734.1 - 0.0066 16.4 0.0 0.72 9.7 0.0 2.2 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 NACHT PF05729.12 EGD83734.1 - 0.0082 16.1 0.1 4.8 7.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 EGD83734.1 - 0.0086 16.5 0.0 1.1 9.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase GTP_EFTU PF00009.27 EGD83734.1 - 0.012 15.2 0.1 13 5.3 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EGD83734.1 - 0.012 16.2 0.0 7.2 7.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Septin PF00735.18 EGD83734.1 - 0.013 14.8 0.0 0.88 8.8 0.1 2.4 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 EGD83734.1 - 0.017 14.7 0.1 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGD83734.1 - 0.018 15.2 0.3 4.1 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGD83734.1 - 0.027 14.2 0.1 0.54 9.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EGD83734.1 - 0.028 14.2 2.1 2.9 7.6 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MCM PF00493.23 EGD83734.1 - 0.034 13.2 0.0 1.7 7.7 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 EGD83734.1 - 0.035 13.5 0.4 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family EF-hand_8 PF13833.6 EGD83734.1 - 0.035 13.9 0.5 5.2 7.0 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair AAA_7 PF12775.7 EGD83734.1 - 0.047 13.2 0.1 1.9 8.0 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region EF-hand_5 PF13202.6 EGD83734.1 - 0.054 13.0 6.4 0.87 9.2 0.3 3.0 3 0 0 3 3 2 0 EF hand SMC_N PF02463.19 EGD83734.1 - 0.068 12.6 0.3 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 EGD83734.1 - 0.083 12.9 0.3 26 4.8 0.0 3.0 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EGD83734.1 - 0.09 11.9 0.2 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EGD83734.1 - 0.14 11.4 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 EGD83734.1 - 0.16 12.4 0.3 16 5.9 0.1 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EGD83734.1 - 1.1 8.8 2.4 8.7 5.9 0.0 3.1 4 1 0 5 5 4 0 CobW/HypB/UreG, nucleotide-binding domain Ysc84 PF04366.12 EGD83735.1 - 9e-43 145.1 0.3 1.8e-42 144.1 0.3 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EGD83735.1 - 1e-12 47.4 0.1 5.2e-12 45.2 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EGD83735.1 - 1.8e-11 43.5 0.0 4.6e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGD83735.1 - 1.1e-10 41.2 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Zds_C PF08632.10 EGD83736.1 - 6.3e-29 99.5 3.3 1.9e-28 97.9 1.6 2.2 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term ArAE_2_N PF10337.9 EGD83737.2 - 6.3e-16 58.5 0.1 1.2e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EGD83737.2 - 2.7e-07 30.8 10.8 2.7e-07 30.8 10.8 2.4 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_1 PF06081.11 EGD83737.2 - 4 7.6 17.2 0.15 12.2 9.4 2.2 2 0 0 2 2 2 0 Aromatic acid exporter family member 1 ANAPC4_WD40 PF12894.7 EGD83738.2 - 3.6e-12 46.4 0.0 8.2e-05 22.8 0.0 3.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGD83738.2 - 6.1e-10 39.5 16.7 0.00017 22.3 0.3 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.11 EGD83738.2 - 0.0016 18.3 0.0 0.017 15.0 0.0 2.1 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EGD83738.2 - 0.0094 14.0 0.0 0.025 12.6 0.0 1.5 1 1 1 2 2 2 1 IKI3 family Vps16_N PF04841.13 EGD83738.2 - 0.075 11.8 0.0 3.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Vps16, N-terminal region Cytochrom_D1 PF02239.16 EGD83738.2 - 0.085 11.4 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain YpsA PF06908.11 EGD83738.2 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family Arf PF00025.21 EGD83739.1 - 1.8e-73 245.7 0.1 2.2e-73 245.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGD83739.1 - 3.9e-14 52.9 0.0 5.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGD83739.1 - 8.6e-12 44.9 0.0 9.8e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGD83739.1 - 1.7e-11 43.9 0.0 2.1e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGD83739.1 - 2.6e-11 43.3 1.5 3e-07 29.9 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGD83739.1 - 2.6e-11 43.3 0.0 3.1e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGD83739.1 - 0.00016 21.7 0.0 0.00044 20.3 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGD83739.1 - 0.033 13.5 0.3 0.053 12.8 0.1 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase FMO-like PF00743.19 EGD83741.1 - 1.5e-15 56.6 0.0 1.7e-13 49.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGD83741.1 - 2.5e-15 56.5 0.0 3.3e-14 52.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGD83741.1 - 1.5e-11 44.1 0.0 2.2e-08 33.6 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGD83741.1 - 2.6e-11 43.3 0.0 7.7e-10 38.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGD83741.1 - 2.5e-06 26.9 0.1 1.4e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EGD83741.1 - 0.0025 18.0 0.2 0.024 14.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EGD83741.1 - 0.015 15.7 0.0 0.57 10.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 EGD83741.1 - 0.02 15.4 1.4 0.27 11.8 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.6 EGD83741.1 - 0.089 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) NAD_binding_9 PF13454.6 EGD83741.1 - 0.12 12.4 0.1 1.9 8.5 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EGD83741.1 - 0.43 9.6 1.3 13 4.7 0.1 2.9 3 0 0 3 3 3 0 FAD binding domain Lipid_DES PF08557.10 EGD83741.1 - 0.44 10.1 1.7 1.1 8.8 0.3 2.2 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) FAD_oxidored PF12831.7 EGD83741.1 - 0.5 9.7 2.2 6 6.1 1.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase F-box-like PF12937.7 EGD83742.1 - 1.3e-05 25.0 1.5 5.2e-05 23.0 1.5 2.0 1 1 0 1 1 1 1 F-box-like Androgen_recep PF02166.16 EGD83742.1 - 0.25 10.2 2.3 0.35 9.7 2.3 1.1 1 0 0 1 1 1 0 Androgen receptor F-box PF00646.33 EGD83742.1 - 1.6 8.7 4.4 4.1 7.4 0.4 2.5 2 0 0 2 2 2 0 F-box domain Copper-fist PF00649.18 EGD83744.2 - 4.7e-23 80.4 1.4 1.3e-22 79.0 1.4 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain Mito_carr PF00153.27 EGD83747.1 - 3.4e-53 177.6 4.3 8.4e-18 64.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Tir_receptor_N PF07490.11 EGD83747.1 - 0.00045 20.1 1.2 0.00079 19.3 1.2 1.3 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) N-terminus Abhydrolase_1 PF00561.20 EGD83747.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-Nse PF11789.8 EGD83748.2 - 6.2e-22 77.2 1.9 9.9e-22 76.5 1.9 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGD83748.2 - 5.8e-05 23.0 1.1 0.00084 19.3 0.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGD83748.2 - 0.041 13.9 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EGD83748.2 - 0.063 13.1 1.5 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 EGD83748.2 - 0.083 12.7 2.8 0.33 10.7 0.1 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger UPF0560 PF10577.9 EGD83748.2 - 0.32 9.4 6.4 0.55 8.7 6.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pox_Ag35 PF03286.14 EGD83748.2 - 0.52 10.1 13.2 3.8 7.3 8.8 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Prothymosin PF03247.14 EGD83748.2 - 2.1 8.9 31.6 7.9 7.0 0.9 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family Nop14 PF04147.12 EGD83748.2 - 2.3 6.3 22.7 0.15 10.3 15.8 1.9 2 0 0 2 2 2 0 Nop14-like family DUF2722 PF10846.8 EGD83748.2 - 2.6 6.9 15.4 0.36 9.7 9.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Nop25 PF09805.9 EGD83748.2 - 6 7.3 17.8 3.3 8.2 12.2 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Pox_MCEL PF03291.16 EGD83749.2 - 1.7e-53 181.9 0.0 2.7e-50 171.4 0.0 3.3 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.12 EGD83749.2 - 3.7e-10 40.4 0.1 1.7e-08 35.1 0.0 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD83749.2 - 4.7e-10 40.0 0.0 0.0004 21.0 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGD83749.2 - 7.5e-07 29.7 0.6 0.025 15.2 0.0 3.2 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_31 PF13847.6 EGD83749.2 - 5.2e-06 26.3 0.0 0.018 14.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EGD83749.2 - 0.00026 20.3 0.0 0.00051 19.3 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 EGD83749.2 - 0.004 17.0 0.0 0.0099 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGD83749.2 - 6 6.8 0.0 6 6.8 0.0 2.8 3 1 0 3 3 3 0 Methyltransferase domain zf-C3HC PF07967.13 EGD83750.1 - 1.4e-37 128.7 0.5 2.5e-36 124.6 0.1 2.3 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.10 EGD83750.1 - 8.4e-27 93.2 5.4 9.5e-25 86.6 0.1 3.2 3 1 1 4 4 4 2 Rsm1-like RWD PF05773.22 EGD83752.2 - 0.0082 16.4 0.0 0.48 10.7 0.0 2.5 2 0 0 2 2 2 2 RWD domain Polysacc_deac_1 PF01522.21 EGD83753.2 - 1.7e-20 73.2 0.0 3.1e-19 69.1 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide deacetylase RELT PF12606.8 EGD83753.2 - 3.6 6.7 6.3 4.3 6.4 0.1 3.2 3 0 0 3 3 3 0 Tumour necrosis factor receptor superfamily member 19 DUF3295 PF11702.8 EGD83757.1 - 1e-172 575.9 38.7 1e-172 575.9 38.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 EGD83757.1 - 1.1e-11 44.3 2.9 3e-11 42.9 2.9 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ParBc PF02195.18 EGD83757.1 - 0.011 16.0 0.6 0.36 11.1 0.1 3.1 2 1 0 2 2 2 0 ParB-like nuclease domain Cpn60_TCP1 PF00118.24 EGD83768.2 - 7e-159 529.6 3.6 8.2e-159 529.4 3.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 EGD83768.2 - 0.065 13.4 3.8 7 6.8 0.1 3.5 3 1 0 3 3 3 0 Enolase, N-terminal domain Cation_ATPase PF13246.6 EGD83768.2 - 0.14 12.2 0.2 5.9 7.0 0.0 2.6 2 0 0 2 2 2 0 Cation transport ATPase (P-type) Chromo_shadow PF01393.19 EGD83769.2 - 1.8e-20 72.7 0.1 6.5e-16 58.2 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 EGD83769.2 - 2.2e-15 56.3 0.2 4.9e-15 55.2 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SURF2 PF05477.11 EGD83769.2 - 8.9 5.9 10.7 6.1 6.5 0.2 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Rap1_C PF11626.8 EGD83770.2 - 5.1e-19 68.1 0.0 1e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DHHC PF01529.20 EGD83771.2 - 6.2e-32 110.5 6.9 6.2e-32 110.5 6.9 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase Atx10homo_assoc PF09759.9 EGD83772.1 - 1.4e-32 111.6 1.8 1.5e-32 111.6 0.3 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Mce4_CUP1 PF11887.8 EGD83772.1 - 0.15 11.5 0.7 0.98 8.8 0.0 2.5 3 0 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative zf-RING_2 PF13639.6 EGD83774.1 - 1e-08 35.4 3.6 1.5e-08 34.8 3.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGD83774.1 - 2.8e-06 27.5 4.4 4.8e-05 23.6 4.4 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGD83774.1 - 0.00016 21.7 0.7 0.00025 21.0 0.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGD83774.1 - 0.00031 20.7 5.8 0.00054 19.9 5.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGD83774.1 - 0.012 15.5 4.8 0.071 13.0 4.6 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGD83774.1 - 0.017 15.0 2.3 0.17 11.8 2.1 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 EGD83774.1 - 0.023 15.0 0.2 0.055 13.7 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon zf-RING_11 PF17123.5 EGD83774.1 - 0.025 14.3 3.0 0.045 13.5 3.0 1.4 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 EGD83774.1 - 0.4 10.6 3.9 5.1 7.1 1.0 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Putative_PNPOx PF01243.20 EGD83775.1 - 1.5e-09 37.9 0.0 0.00018 21.6 0.0 2.8 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 EGD83775.1 - 5.6e-05 23.4 0.0 0.0039 17.5 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain FAD_binding_8 PF08022.12 EGD83775.1 - 0.18 11.9 0.0 5.3 7.2 0.0 2.3 2 0 0 2 2 2 0 FAD-binding domain MSA-2c PF12238.8 EGD83776.2 - 0.58 10.1 3.2 1.2 9.1 3.2 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c MAGE_N PF12440.8 EGD83776.2 - 3.7 8.3 8.8 0.86 10.3 5.0 1.8 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Bys1 PF04681.12 EGD83777.2 - 5.9e-11 42.5 0.1 8.2e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein NTP_transferase PF00483.23 EGD83778.1 - 3.7e-31 108.6 0.0 4.9e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EGD83778.1 - 1.1e-08 34.5 7.4 4.1e-06 26.3 0.1 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EGD83778.1 - 2e-08 34.8 0.0 3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EGD83778.1 - 0.011 15.5 0.0 0.036 13.8 0.0 1.7 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 EGD83778.1 - 0.082 12.7 2.0 0.53 10.1 0.0 3.0 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Dynamin_N PF00350.23 EGD83779.1 - 1.3e-22 80.7 0.0 5.3e-22 78.7 0.0 2.0 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGD83779.1 - 2.7e-20 72.8 0.0 4.8e-16 58.8 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 EGD83779.1 - 1.5e-05 25.0 0.7 5.1e-05 23.4 0.7 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGD83779.1 - 0.00073 19.6 0.0 0.011 15.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGD83779.1 - 0.0095 16.1 0.0 0.047 13.9 0.1 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGD83779.1 - 0.14 11.8 0.1 0.31 10.6 0.1 1.6 1 0 0 1 1 1 0 Ras family tRNA-synt_2 PF00152.20 EGD83780.2 - 2.8e-78 263.1 0.3 3.8e-78 262.7 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGD83780.2 - 2.7e-12 46.5 0.0 7.8e-12 45.0 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGD83780.2 - 1.3e-05 24.9 0.1 0.018 14.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) PPP1R35_C PF15503.6 EGD83781.1 - 0.092 12.6 1.7 0.28 11.0 1.7 1.8 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Prok-RING_2 PF14445.6 EGD83781.1 - 0.15 12.3 5.9 0.33 11.2 5.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-RING_4 PF14570.6 EGD83781.1 - 0.29 11.0 4.2 0.56 10.0 4.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RanBP PF00641.18 EGD83781.1 - 0.81 9.1 10.6 0.019 14.3 4.2 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others TFIIE-A_C PF11521.8 EGD83781.1 - 7 7.0 7.1 7.4 6.9 0.0 3.1 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha COX15-CtaA PF02628.15 EGD83782.1 - 3.6e-114 381.2 5.7 4.3e-114 380.9 5.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Glyoxalase PF00903.25 EGD83783.1 - 3.1e-24 85.6 1.0 2.5e-17 63.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGD83783.1 - 3.8e-14 52.9 0.2 1.4e-06 28.5 0.2 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGD83783.1 - 1.1e-07 32.1 0.1 0.00084 19.5 0.2 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EGD83783.1 - 0.00044 20.5 0.2 0.0064 16.7 0.2 2.3 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF4844 PF16133.5 EGD83783.1 - 0.029 14.9 0.0 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) TPR_17 PF13431.6 EGD83784.2 - 0.00048 20.3 0.1 0.035 14.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat HgmA PF04209.13 EGD83785.2 - 1.8e-208 692.5 0.0 2e-208 692.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.18 EGD83786.2 - 1.4e-54 185.1 0.0 2e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EGD83786.2 - 7.4e-32 109.7 0.0 1.3e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N PF02798.20 EGD83787.1 - 1.9e-10 40.9 0.0 4.1e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGD83787.1 - 8.4e-10 38.8 0.0 2e-09 37.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGD83787.1 - 3.8e-09 36.8 0.0 6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGD83787.1 - 1.3e-08 34.9 0.1 3.8e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGD83787.1 - 1.6e-06 28.3 0.1 4.9e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGD83787.1 - 0.00036 20.5 0.2 0.00077 19.4 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TYW3 PF02676.14 EGD83787.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TYW3 Oxidored_FMN PF00724.20 EGD83790.1 - 1.1e-56 192.6 0.0 1.3e-56 192.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family BATS PF06968.13 EGD83791.1 - 5.5e-22 77.7 0.1 2e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EGD83791.1 - 6.7e-15 55.9 0.1 1.5e-14 54.7 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_3 PF00202.21 EGD83792.2 - 8.8e-41 139.9 0.0 7.1e-20 71.0 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-III DUF1990 PF09348.10 EGD83792.2 - 0.13 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) Endonuc-PvuII PF09225.10 EGD83792.2 - 0.21 11.3 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease PvuII Aminotran_1_2 PF00155.21 EGD83793.1 - 3.1e-40 138.5 0.0 3.8e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGD83793.1 - 0.028 13.4 0.0 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGD83793.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GTP_EFTU PF00009.27 EGD83794.1 - 2e-40 138.4 0.0 3e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGD83794.1 - 5.2e-30 104.0 0.1 1.2e-29 102.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGD83794.1 - 9e-10 38.8 0.4 2e-09 37.7 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGD83794.1 - 0.062 13.4 0.0 0.19 11.9 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase CTP_transf_like PF01467.26 EGD83795.1 - 1.8e-24 86.5 0.0 2.5e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Ran-binding PF05508.11 EGD83796.2 - 1.1e-23 83.7 0.0 1.6e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 RanGTP-binding protein USP7_ICP0_bdg PF12436.8 EGD83797.2 - 1.1e-23 83.9 0.0 2.5e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 EGD83797.2 - 1.3e-23 83.9 0.5 2e-23 83.2 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase BSD PF03909.17 EGD83798.1 - 1.3e-19 69.9 0.6 3.3e-19 68.6 0.6 1.7 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 EGD83798.1 - 0.01 15.8 3.2 0.016 15.2 3.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CytadhesinP1 PF12378.8 EGD83798.1 - 0.17 12.1 0.1 0.45 10.7 0.1 1.7 1 0 0 1 1 1 0 Trypsin-sensitive surface-exposed protein BHD_3 PF10405.9 EGD83800.2 - 2.4e-29 101.5 0.1 6.4e-29 100.2 0.1 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 EGD83800.2 - 4e-28 97.9 0.0 7e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 EGD83800.2 - 8.7e-20 70.3 0.1 2e-19 69.1 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EGD83800.2 - 4.2e-16 59.6 2.5 5.5e-16 59.3 0.8 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 CENP-F_leu_zip PF10473.9 EGD83801.2 - 5.6e-05 23.2 22.5 5.6e-05 23.2 22.5 9.2 1 1 7 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 EGD83801.2 - 0.0021 17.7 157.9 0.35 10.4 38.1 5.1 1 1 2 4 4 4 4 Intermediate filament protein Tropomyosin_1 PF12718.7 EGD83801.2 - 0.0046 17.1 29.2 0.0046 17.1 29.2 9.6 1 1 9 10 10 10 5 Tropomyosin like DUF4200 PF13863.6 EGD83801.2 - 0.009 16.4 21.0 0.009 16.4 21.0 10.0 1 1 10 11 11 11 2 Domain of unknown function (DUF4200) Csm1_N PF18504.1 EGD83801.2 - 0.015 15.7 6.0 0.015 15.7 6.0 16.1 5 3 9 16 16 16 0 Csm1 N-terminal domain DUF3287 PF11690.8 EGD83801.2 - 0.18 11.5 2.7 0.63 9.8 0.2 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF3287) DUF3584 PF12128.8 EGD83801.2 - 5.1 4.5 178.5 0.026 12.1 41.8 4.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) SANT_DAMP1_like PF16282.5 EGD83802.1 - 0.023 14.9 0.0 0.065 13.4 0.0 1.7 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 PTPA PF03095.15 EGD83803.2 - 7.8e-100 334.2 0.0 9.5e-100 333.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF572 PF04502.13 EGD83804.1 - 9.1e-70 235.9 2.0 1e-69 235.7 2.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Bac_rhamnosid_N PF08531.10 EGD83804.1 - 0.055 13.3 0.4 0.087 12.6 0.4 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_3_C PF01915.22 EGD83805.2 - 8.1e-39 133.7 0.0 1.2e-38 133.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EGD83805.2 - 2.6e-18 65.9 0.2 5.2e-18 64.9 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3143 PF11341.8 EGD83805.2 - 0.064 13.6 1.0 17 5.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3143) PNP_UDP_1 PF01048.20 EGD83806.1 - 4.3e-38 130.9 0.0 5.4e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2757 PF10955.8 EGD83806.1 - 0.13 12.6 0.3 0.3 11.4 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2757) BUD22 PF09073.10 EGD83807.2 - 1.7e-73 248.4 23.7 1.4e-48 166.3 12.1 2.0 2 0 0 2 2 2 2 BUD22 SIS PF01380.22 EGD83808.1 - 5.4e-13 48.9 0.0 1.4e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 EGD83808.1 - 4.1e-05 23.6 0.0 8.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 SIS domain BATS PF06968.13 EGD83808.1 - 0.028 14.5 0.0 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 Biotin and Thiamin Synthesis associated domain CheX PF13690.6 EGD83808.1 - 0.2 11.9 1.6 13 6.1 0.1 3.1 3 0 0 3 3 3 0 Chemotaxis phosphatase CheX Ubie_methyltran PF01209.18 EGD83809.2 - 2.7e-78 262.5 0.0 4.3e-78 261.9 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGD83809.2 - 1.2e-15 57.9 0.0 2.2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD83809.2 - 2.3e-14 53.8 0.0 4.7e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD83809.2 - 3.9e-12 46.2 0.0 5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD83809.2 - 3.4e-10 40.6 0.0 5.3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD83809.2 - 1.8e-06 27.9 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGD83809.2 - 0.053 13.4 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase E1_dh PF00676.20 EGD83810.1 - 8.2e-91 304.1 0.2 1e-90 303.8 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EGD83810.1 - 0.00058 19.7 0.1 0.0021 17.9 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EGD83810.1 - 0.023 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 EGD83810.1 - 0.055 12.3 0.0 0.16 10.7 0.0 1.7 2 0 0 2 2 2 0 XFP N-terminal domain Complex1_30kDa PF00329.19 EGD83813.1 - 1.4e-45 154.9 0.0 2e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Glyco_hydro_8 PF01270.17 EGD83814.1 - 0.026 13.4 0.1 0.035 12.9 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 AA_permease_2 PF13520.6 EGD83815.1 - 5.9e-85 285.7 31.1 7e-85 285.4 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease SseC PF04888.12 EGD83815.1 - 0.35 10.4 1.5 0.52 9.9 0.1 1.8 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family PsbN PF02468.15 EGD83815.1 - 0.86 9.5 4.0 0.73 9.7 1.3 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) p450 PF00067.22 EGD83816.2 - 7.3e-40 137.1 0.0 9.1e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.19 EGD83817.1 - 1.7e-99 333.6 0.0 2.1e-99 333.4 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGD83817.1 - 1.2e-14 54.3 0.0 4.2e-12 45.9 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGD83817.1 - 2.5e-11 43.3 0.0 8.8e-09 35.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGD83817.1 - 2.8e-10 39.9 0.2 3.6e-09 36.2 0.1 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGD83817.1 - 4.8e-06 26.6 0.1 0.005 16.8 0.0 3.1 2 2 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGD83817.1 - 0.00011 22.4 0.0 0.00032 20.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGD83817.1 - 0.00021 21.0 0.4 0.39 10.2 0.5 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGD83817.1 - 0.00025 21.5 0.2 0.1 13.2 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 EGD83817.1 - 0.17 12.5 0.8 23 5.6 0.1 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Lyase_1 PF00206.20 EGD83819.1 - 2.6e-112 375.2 0.0 3.8e-112 374.7 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EGD83819.1 - 1e-20 73.9 0.0 2.3e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.12 EGD83819.1 - 0.16 11.9 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Acetyltransf_1 PF00583.25 EGD83821.1 - 2.1e-11 44.1 0.1 3.6e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGD83821.1 - 4.3e-07 29.9 0.0 6.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGD83821.1 - 4.5e-06 27.0 0.3 7.4e-06 26.3 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_S30 PF04758.14 EGD83822.1 - 4.8e-30 103.5 8.6 5.2e-30 103.4 8.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_L24e PF01246.20 EGD83823.1 - 3.8e-29 100.7 1.4 5.1e-29 100.3 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e UQ_con PF00179.26 EGD83824.1 - 3.8e-47 159.5 0.0 4.2e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGD83824.1 - 0.0022 17.7 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGD83824.1 - 0.012 15.5 0.1 0.023 14.6 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 EGD83824.1 - 0.021 15.1 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.32 EGD83825.2 - 4.1e-10 40.1 15.2 0.0024 18.7 0.0 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.22 EGD83825.2 - 0.0058 16.9 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain 4HBT PF03061.22 EGD83826.1 - 5.2e-06 26.7 0.0 1.3e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EGD83826.1 - 0.039 14.1 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) UCH PF00443.29 EGD83827.2 - 5.1e-49 167.1 0.4 6.8e-49 166.7 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGD83827.2 - 7e-12 45.6 10.4 2.4e-11 43.8 10.4 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGD83827.2 - 6.8e-11 41.8 0.0 2e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family DUF2992 PF11208.8 EGD83827.2 - 3.4 7.9 13.6 6.4 7.0 13.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) ARPC4 PF05856.12 EGD83828.1 - 1.1e-78 262.6 3.3 1.2e-78 262.5 3.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Thioredoxin_13 PF18401.1 EGD83829.2 - 0.17 11.8 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DUF2461 PF09365.10 EGD83831.2 - 4e-76 255.6 0.1 8.1e-76 254.6 0.1 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) ORC6 PF05460.13 EGD83831.2 - 7.3 5.8 19.0 8.2 5.6 18.1 1.5 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Zn_clus PF00172.18 EGD83835.1 - 9.6e-09 35.2 7.3 1.4e-08 34.7 7.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EGD83836.1 - 3.1e-66 223.4 0.0 3.5e-65 220.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD83836.1 - 1.2e-33 116.6 0.0 1.7e-32 112.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 EGD83836.1 - 4e-33 113.6 0.2 1e-32 112.3 0.2 1.8 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 EGD83836.1 - 3.2e-05 23.4 0.0 5.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGD83836.1 - 0.00049 19.2 0.0 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGD83836.1 - 0.0064 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGD83836.1 - 0.055 13.4 0.1 0.23 11.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DAO PF01266.24 EGD83838.2 - 3.9e-19 69.4 0.1 4.5e-19 69.2 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF1690 PF07956.11 EGD83839.1 - 6.1e-39 133.6 5.2 3e-19 69.8 2.4 2.0 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Rootletin PF15035.6 EGD83839.1 - 0.015 15.4 1.0 0.18 11.8 0.3 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion POP1 PF06978.11 EGD83840.1 - 1.6e-74 250.3 14.2 3.6e-74 249.2 14.2 1.6 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EGD83840.1 - 1.2e-33 115.3 1.2 4.4e-33 113.5 1.2 2.1 1 0 0 1 1 1 1 POPLD (NUC188) domain Redoxin PF08534.10 EGD83841.1 - 2.2e-37 128.0 0.0 2.4e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGD83841.1 - 4.2e-11 42.8 0.0 5.3e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Phospholip_A2_3 PF09056.11 EGD83844.1 - 5.6e-40 136.4 5.1 6.6e-40 136.2 5.1 1.0 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 DUF604 PF04646.12 EGD83846.1 - 8.7e-09 35.1 0.0 1.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 EGD83846.1 - 0.00081 18.9 0.0 0.002 17.6 0.0 1.6 1 1 0 1 1 1 1 Fringe-like GDI PF00996.18 EGD83847.2 - 1.2e-06 27.3 0.0 1.9e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 GDP dissociation inhibitor Pro_isomerase PF00160.21 EGD83848.1 - 1.4e-54 184.7 0.0 1.5e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.13 EGD83849.1 - 1.5e-59 201.9 0.8 5.1e-59 200.1 0.8 1.8 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EGD83849.1 - 0.00016 21.3 3.7 0.00016 21.3 3.7 2.1 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease NAD_binding_6 PF08030.12 EGD83852.1 - 8e-20 71.5 0.0 2.9e-19 69.7 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGD83852.1 - 7.5e-18 64.8 9.4 7.5e-18 64.8 9.4 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGD83852.1 - 1.5e-13 50.8 0.0 4.3e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EGD83852.1 - 0.0089 16.7 0.0 7.4 7.3 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 EGD83852.1 - 0.013 16.0 1.0 0.013 16.0 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) DUF2975 PF11188.8 EGD83852.1 - 0.17 11.8 0.0 0.17 11.8 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2975) Acetyltransf_1 PF00583.25 EGD83853.1 - 0.013 15.8 0.0 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGD83853.1 - 0.015 15.7 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sgf11 PF08209.11 EGD83854.1 - 8.2e-08 31.7 1.7 7.9e-07 28.5 0.1 2.6 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) Tetraspanin PF00335.20 EGD83855.2 - 0.011 15.5 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 0 Tetraspanin family SRF-TF PF00319.18 EGD83856.2 - 3.7e-21 74.3 0.1 5.5e-21 73.8 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Lactonase PF10282.9 EGD83857.1 - 1.3e-85 287.7 0.0 1.6e-85 287.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Mg_trans_NIPA PF05653.14 EGD83858.1 - 3.6e-14 52.6 11.4 5.1e-08 32.4 2.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EGD83858.1 - 3.8e-06 27.1 0.9 3.8e-06 27.1 0.9 3.2 4 0 0 4 4 4 1 EamA-like transporter family PUNUT PF16913.5 EGD83858.1 - 0.0001 21.7 0.4 0.0001 21.7 0.4 2.2 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 EGD83858.1 - 0.0014 17.9 1.2 0.0028 16.9 1.1 1.5 1 1 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 EGD83858.1 - 0.015 16.0 5.3 0.15 12.7 0.1 2.8 2 0 0 2 2 2 0 Small Multidrug Resistance protein DUF4079 PF13301.6 EGD83858.1 - 0.022 14.9 0.3 0.022 14.9 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) TMEM61 PF15105.6 EGD83858.1 - 0.053 13.4 0.1 0.096 12.5 0.1 1.4 1 0 0 1 1 1 0 TMEM61 protein family EMP24_GP25L PF01105.24 EGD83858.1 - 0.26 11.2 0.5 0.4 10.6 0.5 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD vATP-synt_E PF01991.18 EGD83859.1 - 5.1e-59 199.0 11.4 5.9e-59 198.8 11.4 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.6 EGD83859.1 - 0.01 16.2 4.5 4.6 7.7 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) IFS PF16718.5 EGD83859.1 - 0.05 13.7 0.6 0.33 11.0 0.5 2.0 2 0 0 2 2 2 0 Immunity factor for SPN 4PPT_N PF17837.1 EGD83859.1 - 0.066 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain PhoLip_ATPase_C PF16212.5 EGD83863.1 - 1.9e-79 266.9 20.1 1.9e-79 266.9 20.1 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGD83863.1 - 1.3e-19 69.7 2.0 3.2e-19 68.4 2.0 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGD83863.1 - 4.1e-12 46.0 0.0 2e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGD83863.1 - 1.8e-10 41.5 0.3 1.3e-05 25.6 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGD83863.1 - 0.00012 21.7 0.1 0.00048 19.7 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGD83863.1 - 0.022 14.5 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SEN1_N PF12726.7 EGD83864.2 - 6.8e-209 695.8 6.2 8.5e-209 695.5 6.2 1.1 1 0 0 1 1 1 1 SEN1 N terminal Sigma70_r1_1 PF03979.14 EGD83864.2 - 0.14 12.2 2.0 0.34 11.0 0.8 2.3 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 CAP59_mtransfer PF11735.8 EGD83866.1 - 6.5e-70 235.6 0.0 1e-69 234.9 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CorA PF01544.18 EGD83869.1 - 3.6e-09 36.4 0.0 6.8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ApoL PF05461.11 EGD83869.1 - 0.07 12.4 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Apolipoprotein L PhetRS_B1 PF18262.1 EGD83869.1 - 0.18 12.1 0.2 23 5.3 0.1 2.8 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain WH1 PF00568.23 EGD83870.1 - 1.5e-28 98.9 0.0 2.3e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 EGD83870.1 - 0.00063 19.5 2.3 0.0011 18.8 0.1 2.5 2 0 0 2 2 2 1 WH2 motif DUF3782 PF12644.7 EGD83871.1 - 0.14 12.3 0.8 0.23 11.6 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) eIF-1a PF01176.19 EGD83872.1 - 4.7e-22 77.6 0.0 6.5e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.15 EGD83873.2 - 2.4e-18 66.8 0.0 7.7e-18 65.2 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.6 EGD83873.2 - 0.18 12.4 0.0 0.82 10.3 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix domain fn3_2 PF16893.5 EGD83874.1 - 7.6e-38 128.6 0.1 1.3e-37 127.8 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EGD83874.1 - 7.4e-24 83.4 0.5 1.4e-23 82.5 0.5 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EGD83874.1 - 1.5e-14 53.7 0.0 2.6e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EGD83874.1 - 1.7e-07 31.5 0.0 3.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 EGD83874.1 - 1.3e-05 25.3 0.0 4.4e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 EGD83874.1 - 3.9e-05 24.0 0.0 9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 EGD83874.1 - 0.0023 18.2 0.0 0.0084 16.4 0.0 1.9 1 1 0 1 1 1 1 Fibronectin type III domain Peptidase_S10 PF00450.22 EGD83875.2 - 2.9e-69 234.5 0.0 4.3e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_7 PF13508.7 EGD83876.1 - 0.021 15.2 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGD83876.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGD83877.1 - 7e-09 36.0 0.0 1e-08 35.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGD83877.1 - 1.6e-07 31.3 0.0 3.9e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGD83877.1 - 6.9e-06 26.2 0.1 1.9e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGD83877.1 - 2.3e-05 24.7 0.0 3.9e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EGD83877.1 - 0.0084 16.3 0.0 0.053 13.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGD83877.1 - 0.029 14.5 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GFA PF04828.14 EGD83878.1 - 8.7e-11 42.0 0.5 4.3e-05 23.8 0.0 2.3 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.16 EGD83879.1 - 3.2e-47 161.2 36.4 3.2e-47 161.2 36.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD83879.1 - 3.3e-12 46.0 10.7 3.3e-12 46.0 10.7 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 EGD83879.1 - 8.8e-06 25.2 5.6 8.8e-06 25.2 5.6 2.3 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB CAAD PF14159.6 EGD83879.1 - 0.052 13.4 0.1 0.27 11.1 0.1 2.4 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase MFS_1 PF07690.16 EGD83880.1 - 1.4e-18 67.0 59.6 5.2e-17 61.8 54.4 3.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD83880.1 - 2.2e-08 33.4 33.6 3.1e-06 26.3 14.6 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EGD83880.1 - 1.2e-07 30.6 15.3 1.2e-07 30.6 15.3 2.2 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Evr1_Alr PF04777.13 EGD83881.1 - 2.7e-25 88.7 0.0 4.5e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Erv1 / Alr family FAD_SOX PF18371.1 EGD83881.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase R3H PF01424.22 EGD83883.1 - 1.3e-12 47.5 0.1 3.9e-12 46.0 0.1 1.9 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.17 EGD83883.1 - 0.00026 21.0 52.8 0.00072 19.6 14.5 14.2 14 2 1 15 15 15 7 NF-X1 type zinc finger Caldesmon PF02029.15 EGD83885.1 - 0.1 11.3 8.2 0.12 11.1 8.2 1.1 1 0 0 1 1 1 0 Caldesmon ARID PF01388.21 EGD83886.1 - 2.2e-18 66.7 0.0 2.2e-18 66.7 0.0 2.3 2 1 0 2 2 2 1 ARID/BRIGHT DNA binding domain Cnd2 PF05786.14 EGD83886.1 - 0.00019 20.3 0.3 0.00019 20.3 0.3 2.8 2 1 1 3 3 3 1 Condensin complex subunit 2 Presenilin PF01080.17 EGD83886.1 - 0.83 8.4 23.8 0.15 10.8 13.0 2.4 2 0 0 2 2 2 0 Presenilin Img2 PF05046.14 EGD83887.1 - 6.4e-26 90.5 0.0 9.1e-26 90.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.10 EGD83888.1 - 1.1e-48 165.0 2.3 2.8e-48 163.7 2.3 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EGD83888.1 - 5e-14 52.7 0.0 1.4e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain DUF445 PF04286.12 EGD83888.1 - 7.9 6.2 7.9 1.3 8.8 2.4 2.3 2 2 0 2 2 2 0 Protein of unknown function (DUF445) ArsA_ATPase PF02374.15 EGD83891.2 - 1.7e-112 375.6 0.0 1.9e-112 375.4 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EGD83891.2 - 1.1e-13 51.4 0.2 4.4e-12 46.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 EGD83891.2 - 1.6e-12 47.6 0.0 3.1e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EGD83891.2 - 6.7e-06 25.7 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 EGD83891.2 - 7.5e-06 25.6 0.9 0.00019 21.0 0.1 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 EGD83891.2 - 1.7e-05 24.6 0.2 0.00065 19.4 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 EGD83891.2 - 8.3e-05 22.2 0.0 0.00029 20.4 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 EGD83891.2 - 0.056 12.9 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 EGD83891.2 - 0.076 12.2 0.0 0.2 10.8 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 EGD83891.2 - 0.16 12.5 0.0 0.9 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGD83891.2 - 0.21 11.2 0.1 0.73 9.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain NAD_binding_6 PF08030.12 EGD83892.2 - 4.1e-19 69.2 0.0 5e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGD83892.2 - 0.0024 18.0 0.0 0.0064 16.6 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EGD83892.2 - 0.0041 17.7 0.0 1.8 9.2 0.0 2.3 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain Transthyretin PF00576.21 EGD83893.1 - 6.5e-29 100.8 0.0 9.3e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family Aft1_HRR PF11787.8 EGD83894.2 - 2.4e-19 70.2 2.5 2.4e-19 70.2 2.5 4.0 2 1 1 3 3 3 1 Aft1 HRR domain Aft1_HRA PF11786.8 EGD83894.2 - 1.4e-18 67.0 10.6 1.4e-18 67.0 10.6 2.9 3 0 0 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.21 EGD83894.2 - 3.9e-08 33.3 10.7 6.7e-08 32.5 10.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGD83894.2 - 0.0021 18.1 9.7 0.0045 17.0 9.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGD83894.2 - 0.022 15.3 4.3 0.048 14.2 4.3 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Nop53 PF07767.11 EGD83894.2 - 0.14 11.5 15.4 0.21 10.9 15.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) HeLo PF14479.6 EGD83894.2 - 1.1 9.1 5.8 1.4 8.7 5.1 1.5 1 1 0 1 1 1 0 Prion-inhibition and propagation PARP PF00644.20 EGD83895.1 - 3.6e-11 43.0 0.3 9.1e-11 41.7 0.3 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 EGD83895.1 - 2.3e-08 33.8 0.0 4.7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGD83895.1 - 0.038 14.3 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 RWD domain COG5 PF10392.9 EGD83896.1 - 0.48 10.6 3.0 9.4 6.4 0.5 2.6 1 1 1 2 2 2 0 Golgi transport complex subunit 5 RNA_pol_Rpb4 PF03874.16 EGD83897.1 - 1.5e-07 31.8 0.5 0.0089 16.4 0.0 2.4 2 1 0 2 2 2 2 RNA polymerase Rpb4 Nop PF01798.18 EGD83898.1 - 1.1e-83 280.2 0.5 1.1e-83 280.2 0.5 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGD83898.1 - 3.2e-21 75.5 0.6 3.2e-21 75.5 0.6 2.9 4 0 0 4 4 4 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.16 EGD83899.1 - 8.6e-109 364.1 0.1 9.6e-109 363.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pribosyl_synth PF14572.6 EGD83901.1 - 2.8e-40 138.3 1.9 9.4e-36 123.6 0.6 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EGD83901.1 - 9.2e-34 115.9 0.0 2e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EGD83901.1 - 8.5e-14 51.4 0.2 1.8e-13 50.3 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGD83901.1 - 0.0018 17.7 0.1 0.003 17.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase YukD PF08817.10 EGD83902.2 - 0.0026 18.4 0.0 0.0042 17.7 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.23 EGD83902.2 - 0.0027 17.4 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family PIG-H PF10181.9 EGD83903.1 - 2.2e-27 94.7 1.1 1.1e-26 92.5 0.2 2.2 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.20 EGD83904.2 - 5.7e-35 120.1 0.0 2.1e-34 118.2 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridine synthase Pox_A_type_inc PF04508.12 EGD83904.2 - 0.0059 16.4 0.2 0.015 15.1 0.2 1.8 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Amidoligase_2 PF12224.8 EGD83905.2 - 1.4e-08 34.7 0.0 3.3e-07 30.3 0.0 2.5 1 1 0 1 1 1 1 Putative amidoligase enzyme Ribosomal_S2 PF00318.20 EGD83906.1 - 5.1e-26 91.2 0.1 3e-14 52.8 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EGD83906.1 - 1.9e-05 25.9 21.4 3.7e-05 25.0 21.4 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 EGD83907.1 - 8.7e-25 86.8 1.3 2.9e-24 85.1 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 Hanta_nucleocap PF00846.18 EGD83907.1 - 0.006 15.1 1.2 0.0071 14.8 0.2 1.6 2 0 0 2 2 2 1 Hantavirus nucleocapsid protein DEAD PF00270.29 EGD83909.1 - 7e-37 126.9 0.0 3.6e-36 124.6 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD83909.1 - 6.5e-21 74.8 0.0 2.9e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGD83909.1 - 1.2e-19 70.3 0.0 2.6e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGD83909.1 - 0.016 15.2 0.0 0.052 13.5 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGD83909.1 - 0.042 14.1 0.2 0.64 10.3 0.2 2.4 1 1 0 1 1 1 0 AAA domain Pinin_SDK_memA PF04696.13 EGD83909.1 - 1.7 8.7 14.8 2.8 8.0 14.8 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region XPG_I PF00867.18 EGD83911.2 - 3.7e-22 78.5 0.1 7.7e-22 77.5 0.1 1.6 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 EGD83911.2 - 1.1e-16 61.6 0.4 1.1e-16 61.6 0.4 2.2 1 1 1 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 EGD83911.2 - 9.1e-08 32.5 0.0 2.4e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EGD83911.2 - 0.018 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing Actin PF00022.19 EGD83912.1 - 3.4e-22 78.6 0.0 3.5e-19 68.7 0.0 2.9 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 EGD83912.1 - 0.072 11.9 0.0 0.24 10.2 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Aldose_epim PF01263.20 EGD83914.1 - 4.5e-50 170.7 0.1 6e-50 170.3 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.25 EGD83916.1 - 1.6e-13 50.6 0.0 3.5e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD83916.1 - 5.1e-10 39.1 0.0 1.9e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Sec34 PF04136.15 EGD83918.2 - 2e-49 167.3 0.2 4.2e-49 166.2 0.2 1.6 1 0 0 1 1 1 1 Sec34-like family Mannitol_dh_C PF08125.13 EGD83921.1 - 3.4e-41 141.3 0.1 9.4e-41 139.9 0.0 1.7 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EGD83921.1 - 8.7e-19 68.2 0.3 2.3e-18 66.8 0.2 1.8 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 EGD83921.1 - 0.066 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGD83921.1 - 0.095 13.0 0.1 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain L31 PF09784.9 EGD83921.1 - 0.12 12.8 0.3 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 RCC1 PF00415.18 EGD83922.1 - 3.8e-33 113.9 6.4 5.6e-08 33.3 0.3 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGD83922.1 - 2.5e-16 59.0 20.6 2.2e-05 24.1 0.2 6.1 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.13 EGD83923.1 - 2.3e-49 168.1 0.0 2.9e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 EGD83923.1 - 0.004 16.2 0.0 0.023 13.8 0.0 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Sushi_2 PF09014.10 EGD83923.1 - 0.0055 16.6 0.3 0.022 14.7 0.2 2.0 2 0 0 2 2 2 1 Beta-2-glycoprotein-1 fifth domain Pkinase PF00069.25 EGD83924.1 - 4.3e-63 213.2 0.0 6.8e-63 212.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD83924.1 - 2e-43 148.5 0.0 3.5e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD83924.1 - 2.5e-10 40.2 0.0 7.2e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGD83924.1 - 0.0029 16.5 0.0 0.0076 15.1 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGD83924.1 - 0.003 16.9 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RepL PF05732.11 EGD83924.1 - 0.058 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) APH PF01636.23 EGD83924.1 - 0.078 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mrx7 PF10906.8 EGD83925.1 - 1.9e-11 44.0 0.0 3.1e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 MIOREX complex component 7 GCP_C_terminal PF04130.13 EGD83927.2 - 8.4e-102 340.8 0.0 1.8e-101 339.7 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGD83927.2 - 3.8e-81 273.1 0.1 3.6e-80 269.9 0.0 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF2373 PF10180.9 EGD83928.1 - 1.1e-20 73.2 0.1 2e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.26 EGD83929.1 - 3.9e-48 163.5 0.0 5.5e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGD83929.1 - 4.6e-13 48.6 0.3 8.3e-13 47.8 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SCP2 PF02036.17 EGD83929.1 - 0.041 14.4 0.0 0.092 13.2 0.0 1.6 1 0 0 1 1 1 0 SCP-2 sterol transfer family Amidase_5 PF05382.13 EGD83929.1 - 0.057 13.3 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase Rbx_binding PF18113.1 EGD83930.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain PTR2 PF00854.21 EGD83934.2 - 4.4e-36 124.6 4.0 5.8e-36 124.2 4.0 1.1 1 0 0 1 1 1 1 POT family Glyco_hydro_18 PF00704.28 EGD83935.1 - 3.7e-88 296.2 0.9 4.4e-88 296.0 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.23 EGD83936.1 - 3.4e-31 106.8 0.6 5.8e-31 106.1 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EGD83936.1 - 1.5e-26 92.3 1.9 1.5e-26 92.3 1.9 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EGD83936.1 - 2.6e-13 49.6 0.7 4.7e-13 48.8 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EGD83936.1 - 0.0014 18.7 0.6 0.0045 17.1 0.6 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGD83936.1 - 0.0044 17.5 0.1 0.023 15.1 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin-like domain IBR PF01485.21 EGD83936.1 - 0.013 15.7 0.3 0.021 15.1 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 EGD83936.1 - 0.017 15.2 0.5 6.4 6.9 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 EGD83936.1 - 0.018 15.6 0.7 0.025 15.1 0.7 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain zf-H2C2_2 PF13465.6 EGD83937.1 - 1.8e-09 37.6 5.1 0.0013 19.1 0.1 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGD83937.1 - 3.1e-07 30.5 17.1 0.00099 19.4 4.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD83937.1 - 6.4e-06 26.6 14.7 0.0071 17.1 3.4 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGD83937.1 - 0.05 13.6 7.1 1.3 9.1 2.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EGD83937.1 - 0.16 11.7 7.2 0.085 12.6 2.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 EGD83937.1 - 0.17 12.3 1.4 0.45 11.0 1.4 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 EGD83937.1 - 1.3 9.1 6.8 1.7 8.8 3.7 2.4 1 1 1 2 2 2 0 BED zinc finger zf-LYAR PF08790.11 EGD83937.1 - 7.2 6.6 9.0 30 4.6 0.0 3.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DUF155 PF02582.14 EGD83938.1 - 2.4e-50 171.1 0.0 3.3e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.20 EGD83939.1 - 3.8e-19 69.0 0.1 1.5e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40_like PF17005.5 EGD83939.1 - 0.008 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 WD40-like domain zf-RING_5 PF14634.6 EGD83939.1 - 0.015 15.2 0.3 0.015 15.2 0.3 1.9 2 0 0 2 2 2 0 zinc-RING finger domain WD40 PF00400.32 EGD83939.1 - 0.066 14.1 0.5 80 4.4 0.0 4.3 3 1 0 3 3 3 0 WD domain, G-beta repeat Vps39_1 PF10366.9 EGD83939.1 - 0.097 13.0 0.1 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 RXT2_N PF08595.11 EGD83939.1 - 2.4 8.2 4.7 5.8 6.9 4.7 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 EGD83939.1 - 8.9 6.0 8.2 19 5.0 8.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CP2 PF04516.15 EGD83941.2 - 1.1e-77 260.4 0.1 1.8e-77 259.7 0.1 1.3 1 0 0 1 1 1 1 CP2 transcription factor MAAL_N PF05034.13 EGD83941.2 - 0.061 13.0 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase N-terminus ORC6 PF05460.13 EGD83943.2 - 0.017 14.5 1.0 0.02 14.2 1.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Metallopep PF12044.8 EGD83946.1 - 9.2e-103 344.1 0.7 1.1e-102 343.8 0.7 1.1 1 0 0 1 1 1 1 Putative peptidase family GST_N_3 PF13417.6 EGD83948.1 - 4.3e-09 36.7 0.1 7.8e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGD83948.1 - 4.7e-07 29.7 1.7 7.5e-07 29.1 1.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGD83948.1 - 1.4e-06 28.5 0.0 2.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGD83948.1 - 0.0013 18.9 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGD83948.1 - 0.0019 18.4 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGD83948.1 - 0.0023 18.2 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DJ-1_PfpI PF01965.24 EGD83949.1 - 9e-11 41.8 0.0 1.5e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EGD83949.1 - 0.034 13.8 0.4 0.2 11.3 0.4 2.0 1 1 0 1 1 1 0 ThiJ/PfpI family-like DNA_ligase_A_M PF01068.21 EGD83950.1 - 6.6e-51 172.9 0.0 3.2e-48 164.1 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGD83950.1 - 1.2e-37 129.9 0.0 2.1e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGD83950.1 - 1.2e-19 70.8 0.2 4.7e-19 68.8 0.0 2.2 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EGD83950.1 - 0.025 14.9 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA ligase RINT1_TIP1 PF04437.13 EGD83951.1 - 8.8e-181 602.1 1.5 9.9e-181 602.0 0.0 1.8 2 1 0 2 2 2 1 RINT-1 / TIP-1 family Uso1_p115_C PF04871.13 EGD83951.1 - 0.0069 16.7 9.7 0.019 15.3 9.7 1.7 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region SLX9 PF15341.6 EGD83951.1 - 0.012 16.1 4.1 0.025 15.0 4.1 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF4961 PF16328.5 EGD83951.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4961) Nup54 PF13874.6 EGD83951.1 - 0.16 12.1 8.2 0.22 11.6 6.4 2.2 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 CRISPR_Cse2 PF09485.10 EGD83951.1 - 0.58 10.7 4.7 1.4 9.4 3.5 2.4 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) ALMT PF11744.8 EGD83951.1 - 0.8 8.5 6.0 1.3 7.8 6.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF883 PF05957.13 EGD83951.1 - 0.98 10.1 7.1 7.8 7.2 5.4 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) T3SSipB PF16535.5 EGD83951.1 - 1.6 9.2 11.6 1.8 9.1 10.1 1.8 2 0 0 2 2 2 0 Type III cell invasion protein SipB Pyridoxal_deC PF00282.19 EGD83952.1 - 1.2e-78 264.4 0.0 1.5e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGD83952.1 - 2.4e-08 33.3 0.0 3.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGD83952.1 - 5.9e-07 29.0 0.0 6.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 EGD83952.1 - 0.015 14.0 0.0 0.029 13.1 0.0 1.4 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS PUF PF00806.19 EGD83953.2 - 1.1e-11 43.8 0.0 2.3 8.1 0.0 7.6 8 0 0 8 8 8 4 Pumilio-family RNA binding repeat Phage_holin_5_1 PF06946.11 EGD83953.2 - 0.013 15.8 0.9 0.028 14.8 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 Glyoxalase PF00903.25 EGD83954.1 - 8e-05 22.8 0.1 0.00017 21.7 0.1 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EGD83954.1 - 0.0083 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain pXO2-72 PF17443.2 EGD83954.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein pXO2-72 DUF2306 PF10067.9 EGD83956.1 - 1.5e-21 77.2 10.0 3.5e-21 76.0 10.0 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) adh_short PF00106.25 EGD83957.1 - 7e-32 110.5 0.3 1.4e-31 109.5 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD83957.1 - 2.1e-25 89.7 0.2 4.5e-25 88.6 0.1 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD83957.1 - 0.0004 20.3 0.5 0.0011 18.9 0.5 1.7 1 1 0 1 1 1 1 KR domain Sof1 PF04158.14 EGD83958.1 - 2.4e-29 101.5 14.7 4.2e-29 100.6 14.7 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EGD83958.1 - 1.7e-27 95.1 6.0 1.3e-05 25.8 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD83958.1 - 4.8e-09 36.4 0.1 0.033 14.5 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGD83958.1 - 0.00056 19.0 0.0 0.038 12.9 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RPN6_N PF18055.1 EGD83959.1 - 1.2e-44 151.4 1.1 2.5e-44 150.4 0.2 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EGD83959.1 - 6.5e-20 71.6 1.0 1.2e-19 70.7 0.1 1.9 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 EGD83959.1 - 1.5e-11 43.8 0.5 4.1e-11 42.4 0.5 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 EGD83959.1 - 3.3e-06 27.3 13.8 0.0025 18.0 1.2 5.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGD83959.1 - 8.2e-06 25.4 4.4 1.7e-05 24.4 2.7 2.1 1 1 1 2 2 2 1 MalT-like TPR region DDRGK PF09756.9 EGD83959.1 - 0.00026 20.7 0.8 0.00049 19.7 0.2 1.7 2 0 0 2 2 2 1 DDRGK domain TPR_1 PF00515.28 EGD83959.1 - 0.00045 19.9 0.3 4.9 7.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGD83959.1 - 0.0019 18.1 1.9 5.8 7.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGD83959.1 - 0.0089 16.1 4.9 54 4.3 0.3 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGD83959.1 - 0.04 14.6 3.2 1.9 9.4 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 EGD83959.1 - 0.075 13.0 0.0 12 6.0 0.0 2.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain TPR_6 PF13174.6 EGD83959.1 - 0.092 13.4 6.4 15 6.5 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat NepR PF18557.1 EGD83959.1 - 0.16 11.6 0.9 1.7 8.4 0.1 2.7 2 0 0 2 2 2 0 Anti-sigma factor NepR TPR_14 PF13428.6 EGD83959.1 - 0.76 10.8 9.4 25 6.0 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGD83959.1 - 4.4 7.8 9.4 70 4.0 0.0 5.7 7 0 0 7 7 5 0 Tetratricopeptide repeat SWIB PF02201.18 EGD83960.2 - 1.3e-22 79.4 0.0 2.5e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain TRAM_LAG1_CLN8 PF03798.16 EGD83961.1 - 7.3e-50 169.5 15.2 1.1e-49 168.8 15.2 1.3 1 0 0 1 1 1 1 TLC domain DUF948 PF06103.11 EGD83962.1 - 0.0011 19.1 50.5 0.13 12.5 0.0 13.5 9 4 5 15 15 15 5 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EGD83962.1 - 0.0033 17.4 49.7 0.075 13.1 0.0 12.3 7 4 5 13 13 13 5 Protein of unknown function (DUF1664) HALZ PF02183.18 EGD83962.1 - 0.34 11.2 10.7 2.4 8.5 2.7 4.9 5 0 0 5 5 5 0 Homeobox associated leucine zipper SCO1-SenC PF02630.14 EGD83962.1 - 4.6 7.1 7.2 19 5.2 0.0 4.8 4 1 0 5 5 5 0 SCO1/SenC UBA_2 PF08587.11 EGD83962.1 - 7.2 6.8 20.9 66 3.7 0.0 8.7 8 2 2 10 10 10 0 Ubiquitin associated domain (UBA) Ribosomal_L27e PF01777.18 EGD83963.2 - 6.1e-37 125.8 3.1 8e-37 125.5 3.1 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EGD83963.2 - 0.0014 18.5 0.1 0.0047 16.8 0.1 1.9 1 0 0 1 1 1 1 KOW motif Band_7 PF01145.25 EGD83965.1 - 5.8e-27 94.8 2.6 1e-26 94.1 2.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Dak1_2 PF13684.6 EGD83965.1 - 0.016 14.3 1.0 0.023 13.8 1.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Band_7_1 PF13421.6 EGD83965.1 - 0.03 14.0 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family PHD PF00628.29 EGD83966.1 - 2.4e-07 30.5 9.3 5.4e-07 29.4 9.3 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 EGD83966.1 - 0.5 10.3 7.5 1 9.3 7.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 EGD83966.1 - 3.7 7.2 9.1 0.93 9.1 4.5 2.3 2 1 0 2 2 2 0 PHD-finger CoA_transf_3 PF02515.17 EGD83967.1 - 2.2e-128 428.5 0.0 2.5e-128 428.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.17 EGD83968.1 - 6.5e-45 151.0 0.6 1.7e-22 79.2 0.2 2.2 2 0 0 2 2 2 2 Lumazine binding domain Lumazine_bd_2 PF12893.7 EGD83968.1 - 0.0075 16.9 0.1 0.02 15.5 0.0 1.7 1 1 0 1 1 1 1 Putative lumazine-binding YabP PF07873.11 EGD83968.1 - 0.035 13.9 0.1 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 YabP family Brix PF04427.18 EGD83969.2 - 3.8e-37 128.3 0.1 5.4e-37 127.8 0.1 1.2 1 0 0 1 1 1 1 Brix domain DUF2461 PF09365.10 EGD83969.2 - 0.011 15.6 0.5 0.08 12.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) DEAD PF00270.29 EGD83970.1 - 2.8e-47 160.7 0.0 4.4e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD83970.1 - 1.2e-30 106.1 0.0 1.2e-29 102.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD83970.1 - 3.2e-05 24.0 0.0 6.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PGM_PMM_I PF02878.16 EGD83971.1 - 2.1e-18 66.4 0.7 5.2e-08 32.7 0.0 3.2 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EGD83971.1 - 7.9e-11 42.0 1.1 2.2e-10 40.6 0.3 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EGD83971.1 - 0.00048 20.3 0.5 0.0024 18.1 0.5 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGD83971.1 - 0.0017 18.9 0.6 0.012 16.2 0.3 2.6 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Per1 PF04080.13 EGD83972.2 - 9.1e-88 294.3 17.5 1.2e-87 293.9 17.5 1.0 1 0 0 1 1 1 1 Per1-like family NiFe_hyd_3_EhaA PF17367.2 EGD83972.2 - 0.14 12.3 2.3 8.3 6.6 0.1 2.6 2 1 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A DUF2007 PF09413.10 EGD83973.2 - 0.069 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein Methyltransf_25 PF13649.6 EGD83974.1 - 9.8e-12 45.4 0.0 2.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGD83974.1 - 1.2e-10 41.3 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EGD83974.1 - 2.1e-10 40.6 0.0 3.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD83974.1 - 1.2e-07 32.2 0.0 3.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD83974.1 - 9.7e-07 28.8 0.0 2e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGD83974.1 - 4.8e-06 25.7 0.0 6.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EGD83974.1 - 1.9e-05 24.1 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EGD83974.1 - 3.6e-05 23.7 0.4 0.00011 22.2 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGD83974.1 - 0.00029 20.4 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGD83974.1 - 0.0004 21.1 0.0 0.00084 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EGD83974.1 - 0.0067 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EGD83974.1 - 0.017 14.4 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.16 EGD83974.1 - 0.02 14.8 0.1 0.044 13.6 0.1 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 EGD83974.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EGD83974.1 - 0.033 13.9 0.2 0.056 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 EGD83974.1 - 0.036 13.7 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 EGD83974.1 - 0.045 13.5 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase MaoC_dehydratas PF01575.19 EGD83975.1 - 5e-24 84.2 0.0 8.5e-24 83.5 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EGD83975.1 - 9.1e-09 35.5 0.0 0.0022 18.1 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase TauD PF02668.16 EGD83976.1 - 2.7e-37 129.0 0.0 3.8e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EGD83976.1 - 4e-11 43.4 0.0 8.2e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EGD83976.1 - 0.0054 15.9 0.1 0.076 12.1 0.1 2.1 1 1 0 1 1 1 1 CsiD AAA PF00004.29 EGD83977.1 - 1.2e-40 139.0 0.0 3.5e-40 137.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGD83977.1 - 9.8e-19 67.1 0.2 2e-18 66.1 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGD83977.1 - 5.2e-09 35.8 0.0 1.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGD83977.1 - 8.8e-05 22.9 1.9 0.014 15.8 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGD83977.1 - 0.00021 21.3 1.6 0.00072 19.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGD83977.1 - 0.0003 20.6 0.0 0.00072 19.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGD83977.1 - 0.00072 19.8 1.6 0.084 13.1 0.0 3.1 2 1 1 3 3 3 1 AAA domain PhoH PF02562.16 EGD83977.1 - 0.0025 17.3 1.1 0.073 12.5 0.1 2.7 3 0 0 3 3 3 1 PhoH-like protein DUF815 PF05673.13 EGD83977.1 - 0.0027 16.9 1.7 0.051 12.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 EGD83977.1 - 0.0033 17.6 3.2 0.006 16.7 0.0 2.9 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EGD83977.1 - 0.008 15.6 0.1 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGD83977.1 - 0.012 15.8 0.0 0.036 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGD83977.1 - 0.067 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EGD83977.1 - 0.091 12.3 0.3 0.49 9.9 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 EGD83977.1 - 0.53 10.0 0.0 0.53 10.0 0.0 3.2 2 1 1 3 3 2 0 AAA domain CLZ PF16526.5 EGD83977.1 - 1.4 9.3 13.4 0.25 11.7 8.2 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GH-E PF14410.6 EGD83978.1 - 0.012 16.0 0.5 0.033 14.6 0.5 1.7 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues F-box-like PF12937.7 EGD83978.1 - 0.03 14.2 2.4 0.15 11.9 2.4 2.2 1 1 0 1 1 1 0 F-box-like Pkinase PF00069.25 EGD83979.1 - 3.5e-68 229.8 0.0 5.3e-68 229.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD83979.1 - 1.6e-31 109.6 0.0 3.3e-31 108.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGD83979.1 - 1.2e-12 48.3 2.6 2.1e-12 47.5 0.1 2.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGD83979.1 - 6.3e-10 38.8 0.0 2.9e-09 36.7 0.0 1.8 1 1 0 2 2 2 1 Kinase-like C2 PF00168.30 EGD83979.1 - 1.8e-08 34.6 0.0 7.2e-06 26.2 0.0 2.6 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 EGD83979.1 - 0.0022 17.0 0.3 0.0022 17.0 0.3 2.3 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGD83979.1 - 0.0081 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGD83979.1 - 0.07 12.8 0.4 3.1 7.3 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2722 PF10846.8 EGD83985.1 - 0.0006 18.9 4.7 0.0012 17.9 4.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 EGD83985.1 - 0.0038 17.3 10.6 0.0038 17.3 10.6 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Caps_synth_GfcC PF06251.11 EGD83985.1 - 0.029 14.0 3.4 0.045 13.4 3.4 1.2 1 0 0 1 1 1 0 Capsule biosynthesis GfcC Presenilin PF01080.17 EGD83985.1 - 0.11 11.3 0.3 0.14 10.9 0.3 1.2 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EGD83985.1 - 0.32 10.7 2.1 0.55 9.9 2.1 1.3 1 0 0 1 1 1 0 Connexin Peptidase_U57 PF05582.12 EGD83985.1 - 0.52 9.5 4.2 0.78 8.9 4.2 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Peptidase_S49_N PF08496.10 EGD83985.1 - 0.68 10.0 4.8 1.2 9.2 4.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DivIC PF04977.15 EGD83985.1 - 1.3 8.8 6.3 2.8 7.8 6.3 1.5 1 0 0 1 1 1 0 Septum formation initiator Abhydrolase_6 PF12697.7 EGD83987.2 - 2.2e-06 28.4 0.0 3.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGD83987.2 - 4.6e-05 23.2 0.0 8.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD83987.2 - 0.00086 18.6 0.2 0.007 15.7 0.2 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGD83987.2 - 0.047 13.2 0.1 9.8 5.6 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Fungal_trans_2 PF11951.8 EGD83988.2 - 1.8e-07 30.3 1.5 1.8e-07 30.3 1.5 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain His_Phos_1 PF00300.22 EGD83989.1 - 8.4e-30 103.9 0.0 1.8e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 EGD83989.1 - 0.0033 16.8 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Dor1 PF04124.12 EGD83990.1 - 6.9e-53 179.5 4.3 5.7e-42 143.6 4.1 2.6 1 1 1 2 2 2 2 Dor1-like family Sec8_exocyst PF04048.14 EGD83990.1 - 0.064 13.1 0.3 0.19 11.6 0.3 1.8 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Vps51 PF08700.11 EGD83990.1 - 0.17 11.9 1.9 0.29 11.2 0.5 2.2 2 0 0 2 2 2 0 Vps51/Vps67 EAF PF09816.9 EGD83991.1 - 1.8e-16 60.3 0.1 4.6e-16 59.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DUF4811 PF16069.5 EGD83991.1 - 0.055 13.3 0.2 0.055 13.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4811) Cyclin_N PF00134.23 EGD83992.1 - 3.2e-14 52.8 0.1 6.1e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGD83992.1 - 0.0027 17.8 0.1 0.044 13.9 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 EGD83992.1 - 0.0035 17.3 1.9 0.064 13.3 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Chlorovi_GP_rpt PF06598.11 EGD83992.1 - 1.2 9.2 7.9 2.6 8.2 7.9 1.5 1 0 0 1 1 1 0 Chlorovirus glycoprotein repeat PPP4R2 PF09184.11 EGD83992.1 - 2.3 7.7 14.4 3.6 7.1 14.4 1.2 1 0 0 1 1 1 0 PPP4R2 Methyltransf_23 PF13489.6 EGD83994.1 - 3.4e-30 105.1 0.0 4.8e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD83994.1 - 3.1e-05 24.6 0.0 0.00012 22.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD83994.1 - 0.013 16.3 0.0 0.024 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGD83994.1 - 0.019 15.6 0.0 0.056 14.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DAO PF01266.24 EGD83995.1 - 8.5e-49 167.0 0.5 1e-48 166.8 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGD83995.1 - 2.3e-09 36.9 0.0 0.0016 17.7 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGD83995.1 - 2.5e-06 26.9 0.0 4e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EGD83995.1 - 4.1e-06 26.9 0.2 0.073 13.1 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EGD83995.1 - 3.1e-05 23.0 0.2 0.074 11.9 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EGD83995.1 - 5.5e-05 23.3 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGD83995.1 - 0.00029 20.0 0.2 0.23 10.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EGD83995.1 - 0.0031 16.6 0.1 0.52 9.3 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein GMC_oxred_N PF00732.19 EGD83995.1 - 0.0032 16.9 0.0 0.44 9.9 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox PF00070.27 EGD83995.1 - 0.013 16.1 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TBP PF00352.21 EGD83996.2 - 6.7e-67 221.5 0.1 1.2e-32 111.7 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EGD83996.2 - 8.1e-05 22.7 0.0 0.27 11.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EGD83996.2 - 0.17 11.7 0.1 0.84 9.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) ETF_QO PF05187.13 EGD83998.2 - 1.2e-47 160.4 0.7 1.8e-47 159.8 0.7 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_7 PF12838.7 EGD83998.2 - 0.015 15.9 0.9 0.032 14.8 0.9 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain DAO PF01266.24 EGD83998.2 - 0.053 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGD83998.2 - 0.069 13.7 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_2 PF12797.7 EGD83998.2 - 0.11 12.6 0.7 0.27 11.4 0.7 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain RRM_1 PF00076.22 EGD83999.2 - 2.9e-23 81.4 0.1 1.1e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGD83999.2 - 0.00095 19.0 0.0 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif DbpA PF03880.15 EGD83999.2 - 0.059 13.4 0.0 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_3 PF08777.11 EGD83999.2 - 0.2 11.7 0.0 1.3 9.2 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif CSD PF00313.22 EGD83999.2 - 0.22 11.4 0.6 1.4 8.8 0.1 2.1 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain FolB PF02152.18 EGD84000.2 - 3e-12 47.1 0.1 7.9e-07 29.6 0.0 2.8 3 0 0 3 3 3 2 Dihydroneopterin aldolase Pkinase PF00069.25 EGD84001.1 - 1.1e-65 221.6 0.0 1.7e-65 221.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84001.1 - 5e-30 104.6 0.0 7.1e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGD84001.1 - 0.043 12.8 0.2 0.074 12.0 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EGD84001.1 - 0.064 12.0 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGD84001.1 - 0.14 12.1 1.1 3.1 7.6 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RdDM_RDM1 PF09187.10 EGD84002.1 - 0.04 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA-directed DNA methylation 1 Ndc80_HEC PF03801.13 EGD84003.1 - 2.5e-60 202.5 0.5 4.8e-60 201.6 0.5 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Spc7 PF08317.11 EGD84003.1 - 0.018 13.9 39.9 0.21 10.4 18.8 3.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.11 EGD84003.1 - 0.06 12.2 33.5 0.042 12.7 15.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 EGD84003.1 - 1.8 8.6 44.4 0.83 9.7 3.4 4.1 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Cep57_CLD PF14073.6 EGD84003.1 - 3.4 7.7 42.8 0.14 12.2 18.6 3.2 2 1 1 3 3 3 0 Centrosome localisation domain of Cep57 Golgin_A5 PF09787.9 EGD84003.1 - 3.5 7.0 45.7 0.77 9.2 14.5 3.3 2 1 1 3 3 3 0 Golgin subfamily A member 5 CEP63 PF17045.5 EGD84003.1 - 4.8 7.0 39.7 0.86 9.4 12.2 3.3 2 1 1 3 3 3 0 Centrosomal protein of 63 kDa Pex14_N PF04695.13 EGD84004.1 - 3e-41 141.7 0.1 3e-41 141.7 0.1 3.1 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Golgin_A5 PF09787.9 EGD84004.1 - 0.0018 17.8 0.8 0.003 17.1 0.8 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF3584 PF12128.8 EGD84004.1 - 0.03 11.8 5.7 0.048 11.2 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1043 PF06295.12 EGD84004.1 - 0.038 14.0 0.2 0.092 12.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) SYCE1 PF15233.6 EGD84004.1 - 0.075 13.1 3.2 0.13 12.3 3.2 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 LMBR1 PF04791.16 EGD84004.1 - 0.19 10.6 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C4H2 PF10146.9 EGD84004.1 - 0.29 11.4 3.6 0.17 12.2 0.4 2.0 2 1 0 2 2 2 0 Zinc finger-containing protein FlgN PF05130.12 EGD84004.1 - 0.41 11.1 4.9 0.82 10.2 4.9 1.5 1 0 0 1 1 1 0 FlgN protein DUF1664 PF07889.12 EGD84004.1 - 1.3 9.0 2.9 5.3 7.1 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 EGD84005.1 - 4.6 5.7 11.4 6.4 5.2 11.4 1.1 1 0 0 1 1 1 0 Macoilin family ABC_tran PF00005.27 EGD84006.2 - 4.7e-34 117.8 0.0 8.9e-34 117.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGD84006.2 - 7.4e-24 84.9 0.6 1.2e-23 84.1 0.6 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGD84006.2 - 8.6e-06 25.3 0.1 0.00088 18.8 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGD84006.2 - 0.0076 16.8 0.1 0.063 13.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGD84006.2 - 0.016 15.0 0.4 0.048 13.4 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.7 EGD84006.2 - 0.026 13.4 0.0 0.046 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain RsgA_GTPase PF03193.16 EGD84006.2 - 0.031 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 EGD84006.2 - 0.039 14.2 0.1 0.26 11.5 0.1 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EGD84006.2 - 0.055 13.7 0.2 0.24 11.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EGD84006.2 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TTL PF03133.15 EGD84008.2 - 6e-57 193.0 0.0 8.8e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EGD84008.2 - 5.1e-49 166.7 0.0 7.3e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 EGD84008.2 - 0.002 17.4 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp Seipin PF06775.14 EGD84009.2 - 3.8e-43 147.9 0.0 4.6e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Not1 PF04054.15 EGD84010.2 - 1e-137 459.0 1.0 1e-137 459.0 1.0 2.8 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EGD84010.2 - 3.7e-93 311.1 3.5 9.1e-93 309.8 3.5 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EGD84010.2 - 4e-51 172.8 2.0 8.1e-51 171.8 2.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EGD84010.2 - 1.5e-40 138.4 0.0 5.2e-40 136.6 0.0 1.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EGD84010.2 - 4.1e-29 101.6 0.0 9.9e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat FCH PF00611.23 EGD84011.2 - 1.1e-08 35.2 0.1 9.9e-08 32.2 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Glyco_hydro_15 PF00723.21 EGD84011.2 - 0.02 13.7 0.2 0.031 13.1 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 Rapsyn_N PF10579.9 EGD84011.2 - 0.12 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region SH3_1 PF00018.28 EGD84012.1 - 9.2e-14 50.8 0.0 3.3e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGD84012.1 - 1.6e-12 47.1 0.0 5.2e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EGD84012.1 - 2.1e-11 43.3 0.0 7e-11 41.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain DASH_Duo1 PF08651.10 EGD84014.1 - 7.2e-32 109.0 0.1 1.2e-31 108.3 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 Retinal PF15449.6 EGD84014.1 - 0.017 12.9 11.3 0.025 12.4 11.3 1.2 1 0 0 1 1 1 0 Retinal protein DUF745 PF05335.13 EGD84014.1 - 0.055 13.2 7.5 0.099 12.4 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) 3HCDH_N PF02737.18 EGD84014.1 - 0.55 10.1 7.4 0.24 11.2 0.3 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PEARLI-4 PF05278.12 EGD84014.1 - 0.57 9.7 10.4 0.033 13.8 4.8 1.6 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF572 PF04502.13 EGD84014.1 - 1.1 8.8 13.3 1.6 8.3 13.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4637 PF15470.6 EGD84014.1 - 2.3 7.9 10.8 0.19 11.5 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) zf-primase PF09329.11 EGD84016.2 - 1.5e-18 66.3 2.5 2.6e-18 65.5 2.5 1.4 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.10 EGD84017.1 - 7.1e-37 127.1 0.3 7.1e-37 127.1 0.3 3.0 1 1 1 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EGD84017.1 - 1.3e-21 76.6 0.0 3.1e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain U1snRNP70_N PF12220.8 EGD84017.1 - 0.014 16.0 2.7 0.014 16.0 2.7 2.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF1682 PF07946.14 EGD84017.1 - 0.028 13.6 6.4 0.042 13.1 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Selenoprotein_S PF06936.11 EGD84017.1 - 0.35 10.7 8.9 0.63 9.8 8.9 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) ISG65-75 PF11727.8 EGD84017.1 - 0.43 9.8 8.7 0.72 9.0 8.7 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein CPSF100_C PF13299.6 EGD84017.1 - 2.2 8.5 9.1 3.7 7.7 3.9 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Coilin_N PF15862.5 EGD84017.1 - 2.2 8.1 8.8 0.11 12.3 2.9 1.8 2 0 0 2 2 2 0 Coilin N-terminus GalKase_gal_bdg PF10509.9 EGD84018.2 - 6.5e-19 67.2 0.0 1.5e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 EGD84018.2 - 2.5e-15 56.6 0.0 6.2e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EGD84018.2 - 1.8e-13 50.5 2.1 3.5e-13 49.6 2.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain DED PF01335.21 EGD84018.2 - 0.075 13.3 0.2 0.2 12.0 0.2 1.8 1 0 0 1 1 1 0 Death effector domain Turandot PF07240.11 EGD84018.2 - 0.14 12.1 0.0 8.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot TPP_enzyme_N PF02776.18 EGD84020.2 - 3.6e-56 189.5 0.1 1.5e-54 184.2 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGD84020.2 - 1.3e-49 167.9 0.2 2.1e-47 160.7 0.0 2.9 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGD84020.2 - 4.2e-40 136.7 0.2 1.1e-39 135.3 0.2 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EGD84020.2 - 0.037 13.8 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg RINGv PF12906.7 EGD84021.1 - 1.4e-05 25.1 5.8 3.3e-05 23.9 5.8 1.7 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 EGD84021.1 - 4.1e-05 23.7 2.9 0.0001 22.4 2.9 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain PhnA_Zn_Ribbon PF08274.12 EGD84021.1 - 0.0057 16.6 1.5 0.013 15.4 1.5 1.6 1 0 0 1 1 1 1 PhnA Zinc-Ribbon zf-TFIIB PF13453.6 EGD84021.1 - 0.0082 15.5 0.1 0.018 14.4 0.1 1.6 1 0 0 1 1 1 1 Transcription factor zinc-finger zf-RING_2 PF13639.6 EGD84021.1 - 0.18 12.2 7.0 0.099 13.0 4.6 2.0 2 0 0 2 2 2 0 Ring finger domain MRP-L28 PF09812.9 EGD84022.1 - 1.3e-05 25.4 0.1 1.7e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ras PF00071.22 EGD84023.1 - 2.4e-50 170.3 0.0 2.8e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD84023.1 - 1.3e-22 80.3 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD84023.1 - 1.1e-06 28.3 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGD84023.1 - 0.0049 16.3 0.0 0.0054 16.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGD84023.1 - 0.011 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGD84023.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EGD84023.1 - 0.11 12.9 0.1 0.33 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EGD84023.1 - 0.11 12.2 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 EGD84023.1 - 0.21 11.4 0.1 0.43 10.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NST1 PF13945.6 EGD84024.2 - 7.1e-80 267.6 3.7 7.1e-80 267.6 3.7 4.9 3 2 2 5 5 5 1 Salt tolerance down-regulator Vps35 PF03635.17 EGD84025.2 - 4e-281 934.8 0.0 4.5e-281 934.6 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 CobT PF06213.12 EGD84025.2 - 1.9 7.8 7.6 3.6 6.9 7.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1749 PF08538.10 EGD84028.1 - 2.3e-89 299.4 0.0 2.6e-89 299.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 EGD84028.1 - 0.00016 21.0 0.0 0.00026 20.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EGD84028.1 - 0.00031 20.6 0.0 0.0068 16.3 0.0 2.6 3 0 0 3 3 3 1 Serine hydrolase Peptidase_S9 PF00326.21 EGD84028.1 - 0.015 14.8 0.0 0.095 12.2 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGD84028.1 - 0.019 15.6 0.0 0.03 14.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EGD84028.1 - 0.037 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 EGD84028.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glycos_transf_2 PF00535.26 EGD84029.1 - 7.9e-35 120.2 0.0 9.9e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGD84029.1 - 2.4e-14 53.8 0.0 3e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EGD84029.1 - 1.2e-06 28.2 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGD84029.1 - 0.0019 17.7 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 UPA_2 PF17809.1 EGD84029.1 - 0.066 13.0 0.0 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 UPA domain TPR_19 PF14559.6 EGD84030.2 - 2.6e-05 24.6 0.1 0.59 10.7 0.0 3.3 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGD84030.2 - 0.00062 20.0 0.0 0.038 14.3 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGD84030.2 - 0.0007 20.2 0.2 32 5.7 0.0 5.3 4 1 2 6 6 6 0 Tetratricopeptide repeat PknG_TPR PF16918.5 EGD84030.2 - 0.00081 18.2 0.0 0.0023 16.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_6 PF13174.6 EGD84030.2 - 0.0016 19.0 0.1 12 6.8 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGD84030.2 - 0.0019 18.2 0.0 28 5.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGD84030.2 - 0.016 15.8 0.2 37 5.4 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4332 PF14229.6 EGD84030.2 - 0.071 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) HlyIII PF03006.20 EGD84032.1 - 1.3e-60 204.9 13.3 1.6e-60 204.6 13.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related Pkinase PF00069.25 EGD84034.1 - 4.5e-53 180.3 0.0 6.1e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84034.1 - 3.9e-32 111.5 0.0 4.8e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD84034.1 - 0.0023 17.3 0.0 0.0077 15.6 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EGD84034.1 - 0.0026 17.7 0.0 0.012 15.5 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGD84034.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGD84034.1 - 0.1 11.5 0.1 0.31 9.9 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain SR-25 PF10500.9 EGD84035.2 - 0.0027 17.4 5.0 0.0035 17.0 5.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 EGD84039.1 - 2.4e-53 181.2 0.0 3.8e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84039.1 - 1.3e-23 83.7 0.0 7.6e-23 81.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EGD84039.1 - 0.014 14.4 0.2 0.02 13.9 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 EGD84039.1 - 0.017 14.4 0.0 5.9 6.1 0.0 2.4 2 1 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 EGD84039.1 - 1.3 7.7 7.4 4.2 6.0 7.3 2.0 1 1 0 1 1 1 0 Fungal protein kinase TMA7 PF09072.10 EGD84040.1 - 5.6e-25 88.0 23.6 6.2e-25 87.8 23.6 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Filament PF00038.21 EGD84041.2 - 0.089 12.4 0.4 0.13 11.9 0.4 1.1 1 0 0 1 1 1 0 Intermediate filament protein Fib_alpha PF08702.10 EGD84041.2 - 0.12 12.5 3.2 0.34 11.1 3.2 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 EGD84041.2 - 0.2 11.7 1.3 0.34 11.0 1.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4227 PF14004.6 EGD84041.2 - 0.26 11.3 0.1 4.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) Uds1 PF15456.6 EGD84041.2 - 0.28 11.3 1.8 8.5 6.5 0.1 2.3 1 1 1 2 2 2 0 Up-regulated During Septation Cyt-b5 PF00173.28 EGD84042.2 - 1.9e-15 56.7 0.0 2.4e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3381 PF11861.8 EGD84042.2 - 0.21 11.4 0.2 0.26 11.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Ish1 PF10281.9 EGD84043.1 - 8.8e-85 278.7 16.2 3.2e-14 52.9 0.0 7.6 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 EGD84043.1 - 3.7e-08 33.0 0.7 0.33 10.7 0.0 5.2 5 0 0 5 5 5 2 HeH/LEM domain SAP PF02037.27 EGD84043.1 - 5.1e-07 29.3 0.0 0.74 9.6 0.0 4.4 4 0 0 4 4 4 2 SAP domain Slx4 PF09494.10 EGD84043.1 - 0.0022 17.9 0.3 19 5.3 0.0 4.7 5 0 0 5 5 5 0 Slx4 endonuclease ANAPC2 PF08672.11 EGD84043.1 - 0.0056 17.2 0.1 49 4.5 0.0 5.0 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 LEM PF03020.15 EGD84043.1 - 0.026 14.1 0.0 12 5.6 0.0 3.2 3 0 0 3 3 3 0 LEM domain Recombinase PF07508.13 EGD84043.1 - 0.028 14.8 3.4 1.1 9.7 0.2 3.8 2 2 1 3 3 3 0 Recombinase Endonuc-dimeris PF09124.10 EGD84043.1 - 0.029 14.5 0.0 19 5.5 0.0 4.3 6 0 0 6 6 5 0 T4 recombination endonuclease VII, dimerisation SAM_2 PF07647.17 EGD84043.1 - 0.094 12.8 0.3 79 3.5 0.0 4.7 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) DUF1939 PF09154.10 EGD84043.1 - 0.13 12.4 1.9 35 4.7 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1939) YtxH PF12732.7 EGD84043.1 - 0.72 10.4 4.3 11 6.6 0.2 3.9 4 0 0 4 4 4 0 YtxH-like protein DUF2795 PF11387.8 EGD84043.1 - 5.9 7.2 7.9 76 3.6 0.1 4.8 5 0 0 5 5 4 0 Protein of unknown function (DUF2795) PQ-loop PF04193.14 EGD84044.2 - 2.5e-12 46.4 3.5 2.5e-12 46.4 3.5 1.8 2 0 0 2 2 2 1 PQ loop repeat Rick_17kDa_Anti PF05433.15 EGD84046.1 - 0.022 14.6 4.3 0.056 13.3 4.3 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF2951 PF11166.8 EGD84046.1 - 0.031 14.5 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Bacteriocin_IIc PF10439.9 EGD84046.1 - 0.81 9.8 4.2 1.7 8.8 4.2 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 EGD84046.1 - 0.89 9.6 7.6 1.7 8.7 7.6 1.4 1 0 0 1 1 1 0 Glycine zipper GREB1 PF15782.5 EGD84046.1 - 5.3 4.0 13.2 8 3.4 13.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SDA1 PF05285.12 EGD84047.1 - 0.0027 17.2 1.1 0.0048 16.4 1.1 1.3 1 0 0 1 1 1 1 SDA1 FAD_binding_4 PF01565.23 EGD84048.2 - 9.6e-18 64.3 1.3 1.7e-17 63.5 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain Aim21 PF11489.8 EGD84049.1 - 1.9e-168 562.7 94.3 1.9e-168 562.7 94.3 2.3 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 21 Cg6151-P PF10233.9 EGD84050.1 - 1.3e-39 135.0 12.1 1.6e-39 134.7 12.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Trep_Strep PF09605.10 EGD84050.1 - 0.096 12.7 0.5 0.096 12.7 0.5 2.1 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) CbiN PF02553.15 EGD84050.1 - 1 9.4 4.2 0.49 10.4 0.4 2.2 2 0 0 2 2 2 0 Cobalt transport protein component CbiN DUF2721 PF11026.8 EGD84050.1 - 2.1 8.3 11.6 0.51 10.2 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) PRA1 PF03208.19 EGD84050.1 - 8.6 6.0 10.5 17 5.0 10.5 1.5 1 1 0 1 1 1 0 PRA1 family protein ABC2_membrane_2 PF12679.7 EGD84050.1 - 9.4 5.4 12.4 23 4.1 12.0 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein NTF2 PF02136.20 EGD84051.1 - 5.7e-33 114.0 0.1 6.3e-33 113.9 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EGD84051.1 - 0.011 15.7 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 DUF4518 PF15008.6 EGD84051.1 - 0.075 12.2 0.1 0.16 11.1 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Surp PF01805.20 EGD84052.1 - 6.3e-09 35.7 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Surp module DUF1765 PF08578.10 EGD84053.1 - 4.4e-42 143.5 0.8 9e-42 142.5 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) ATP_sub_h PF10775.9 EGD84055.2 - 3.5e-26 91.0 2.6 4.8e-26 90.5 2.6 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 EGD84055.2 - 0.17 12.4 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 TFIIB PF00382.19 EGD84056.1 - 1.9e-37 127.2 0.0 1.6e-19 69.7 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGD84056.1 - 1.3e-10 40.6 0.9 1.3e-10 40.6 0.9 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding RB_B PF01857.20 EGD84056.1 - 0.00032 20.8 0.0 0.00056 20.0 0.0 1.3 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 EGD84056.1 - 0.057 13.5 0.0 2.9 8.0 0.0 2.3 2 1 0 2 2 2 0 Cyclin, C-terminal domain DUF1610 PF07754.11 EGD84056.1 - 0.26 11.3 2.4 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) TFR_dimer PF04253.15 EGD84057.1 - 1.7e-33 115.3 0.1 3.2e-33 114.4 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EGD84057.1 - 1.9e-16 60.4 0.0 4.9e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 EGD84057.1 - 2.1e-13 50.1 0.0 4.6e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 PA domain HMG_CoA_synt_C PF08540.10 EGD84058.1 - 5.5e-103 344.4 0.3 6.9e-103 344.1 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EGD84058.1 - 3.8e-96 320.0 0.1 6.4e-96 319.2 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal GFO_IDH_MocA PF01408.22 EGD84060.2 - 3.3e-06 27.9 0.0 6.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGD84060.2 - 0.0041 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PGM_PMM_I PF02878.16 EGD84061.1 - 9.7e-34 116.0 0.2 1.4e-33 115.5 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EGD84061.1 - 9.2e-26 90.3 0.0 1.7e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGD84061.1 - 5.2e-17 62.3 0.0 1.3e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EGD84061.1 - 7.8e-09 35.6 0.0 1.8e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.24 EGD84062.2 - 7.7e-19 68.8 0.1 1.8e-18 67.6 0.0 1.5 2 0 0 2 2 2 1 Exonuclease Sugar_tr PF00083.24 EGD84066.2 - 8.3e-25 87.5 1.0 3.6e-21 75.5 0.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter Bac_export_1 PF01311.20 EGD84066.2 - 0.034 13.7 0.5 0.034 13.7 0.5 1.7 2 0 0 2 2 2 0 Bacterial export proteins, family 1 Piwi PF02171.17 EGD84069.1 - 1.5e-68 231.3 0.0 3.5e-68 230.1 0.0 1.5 2 0 0 2 2 2 1 Piwi domain ArgoN PF16486.5 EGD84069.1 - 2.4e-21 76.8 0.1 7.2e-21 75.2 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EGD84069.1 - 2.5e-14 52.7 2.3 1.3e-13 50.4 0.2 2.4 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 EGD84069.1 - 1.3e-13 50.9 0.4 2.4e-13 50.0 0.4 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EGD84069.1 - 5.6e-11 42.6 0.0 1.3e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 EGD84069.1 - 6.6e-10 39.2 0.1 1.7e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain PerB PF06590.11 EGD84069.1 - 0.091 13.3 0.1 0.41 11.1 0.0 2.0 2 0 0 2 2 2 0 PerB protein Y_phosphatase PF00102.27 EGD84071.2 - 3e-36 125.1 0.0 4.2e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGD84071.2 - 0.00065 19.8 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGD84071.2 - 0.004 17.2 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EGD84071.2 - 0.0044 16.8 0.3 0.017 14.9 0.2 2.0 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain DUF4746 PF15928.5 EGD84071.2 - 5.8 6.3 9.8 1.1 8.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) VanZ PF04892.12 EGD84072.1 - 4.7e-08 33.7 1.9 6.5e-08 33.3 1.6 1.4 1 1 0 1 1 1 1 VanZ like family Phage_holin_2_4 PF16082.5 EGD84072.1 - 0.18 11.5 0.3 0.76 9.5 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF4131 PF13567.6 EGD84072.1 - 5 6.8 6.9 4.2 7.0 1.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Bromo_TP PF07524.13 EGD84073.2 - 8.6e-09 35.3 0.0 2.3e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated Bromodomain PF00439.25 EGD84073.2 - 6.3e-08 32.6 0.2 1.6e-07 31.3 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP_like PF17027.5 EGD84073.2 - 0.11 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Histone-fold protein DUF3947 PF13135.6 EGD84073.2 - 1.9 8.7 7.1 4.1 7.7 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) TPP_enzyme_N PF02776.18 EGD84074.1 - 1.6e-31 109.3 0.0 2.5e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGD84074.1 - 1.7e-20 73.1 0.0 4.3e-20 71.8 0.0 1.7 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EGD84074.1 - 4.9e-15 55.6 0.0 1.2e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EGD84074.1 - 0.088 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component THUMP PF02926.17 EGD84075.1 - 3.5e-08 33.7 0.0 5.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 THUMP domain Lgl_C PF08596.10 EGD84076.2 - 4.4e-99 331.8 0.0 1.1e-98 330.5 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 EGD84076.2 - 0.13 13.2 5.3 9.8 7.2 0.1 4.6 6 0 0 6 6 6 0 WD domain, G-beta repeat bZIP_1 PF00170.21 EGD84078.1 - 9.6e-07 28.8 7.5 2.2e-06 27.7 7.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGD84078.1 - 0.0069 16.4 7.1 0.0069 16.4 7.1 2.1 2 0 0 2 2 2 1 Basic region leucine zipper CCDC-167 PF15188.6 EGD84078.1 - 0.56 10.6 4.0 1.1 9.6 4.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF1793 PF08760.11 EGD84082.1 - 4.4e-70 235.5 0.1 7.6e-70 234.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 EGD84082.1 - 4.3e-61 205.6 1.0 3e-48 163.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EGD84082.1 - 1.6e-42 145.8 0.1 3.4e-42 144.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 EGD84082.1 - 0.018 14.6 0.2 0.048 13.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) tRNA-synt_1c PF00749.21 EGD84083.1 - 1.7e-100 336.0 0.0 2.2e-100 335.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGD84083.1 - 4.5e-39 134.1 0.2 7.1e-39 133.5 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 EGD84083.1 - 0.0012 19.0 0.1 0.083 13.1 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGD84083.1 - 0.016 15.4 0.0 0.046 13.9 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGD84083.1 - 0.037 14.1 0.0 0.087 12.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DEAD PF00270.29 EGD84087.1 - 4.6e-41 140.5 0.0 9.1e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD84087.1 - 1.3e-29 102.7 0.0 3.4e-29 101.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD84087.1 - 0.00013 22.0 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGD84087.1 - 0.0055 15.5 0.0 0.009 14.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain VEK-30 PF12107.8 EGD84087.1 - 0.24 11.4 1.5 0.47 10.4 1.5 1.5 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway SF1-HH PF16275.5 EGD84089.1 - 1.3e-43 147.9 1.0 3e-43 146.7 1.0 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EGD84089.1 - 1.4e-11 43.9 11.1 2e-05 24.5 3.6 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EGD84089.1 - 4e-08 32.9 0.1 7.9e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EGD84089.1 - 2.4e-06 27.4 6.2 0.0014 18.6 2.9 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EGD84089.1 - 0.00051 19.7 4.7 0.27 11.0 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EGD84089.1 - 0.0029 17.4 8.3 0.54 10.1 1.5 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EGD84089.1 - 0.022 14.6 0.6 0.022 14.6 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle Prim_Zn_Ribbon PF08273.12 EGD84089.1 - 4.5 7.6 7.4 0.73 10.2 3.0 1.9 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase GST_N_3 PF13417.6 EGD84090.2 - 1.4e-15 57.4 0.0 2.4e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGD84090.2 - 1.1e-14 54.5 0.0 1.9e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGD84090.2 - 5.8e-11 42.5 0.0 1.2e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGD84090.2 - 5.3e-10 39.4 0.0 1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGD84090.2 - 1.9e-09 37.6 0.0 3.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGD84090.2 - 5.4e-08 32.8 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NAD_binding_6 PF08030.12 EGD84091.2 - 4.2e-19 69.2 0.0 3.5e-16 59.7 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NUP50 PF08911.11 EGD84092.1 - 0.87 10.3 5.9 1.6 9.4 0.6 3.0 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) CLU PF13236.6 EGD84093.1 - 3.1e-74 249.5 0.0 5.3e-74 248.8 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGD84093.1 - 9.3e-56 188.6 0.0 2.9e-55 187.0 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EGD84093.1 - 5.3e-27 93.9 4.2 1.5e-12 47.6 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 EGD84093.1 - 2.2e-25 88.8 0.3 5.4e-24 84.4 0.1 2.6 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 EGD84093.1 - 3.1e-22 77.7 0.6 1.3e-05 24.9 0.0 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGD84093.1 - 9.2e-05 22.3 4.9 0.3 11.3 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGD84093.1 - 0.004 17.3 4.1 0.14 12.4 0.3 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF727 PF05303.12 EGD84093.1 - 0.0049 16.9 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF727) FHIPEP PF00771.20 EGD84093.1 - 0.23 9.9 1.6 3.5 6.0 0.0 2.4 3 0 0 3 3 3 0 FHIPEP family TPR_17 PF13431.6 EGD84093.1 - 4.6 7.8 5.6 1.7e+02 3.0 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Metallophos PF00149.28 EGD84094.1 - 2e-11 44.8 0.9 3.8e-11 43.9 0.9 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGD84094.1 - 8.8e-09 35.8 0.9 1.1e-07 32.2 0.9 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AAA_16 PF13191.6 EGD84096.2 - 8e-07 29.6 0.3 2.7e-06 27.9 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EGD84096.2 - 0.004 17.1 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EGD84096.2 - 0.0068 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 EGD84096.2 - 0.0075 16.7 0.0 0.02 15.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2859 PF11072.8 EGD84096.2 - 0.013 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) DUF815 PF05673.13 EGD84096.2 - 0.024 13.8 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGD84096.2 - 0.031 14.6 0.4 0.29 11.4 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGD84096.2 - 0.052 13.5 0.0 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Med10 PF09748.9 EGD84098.1 - 3.6e-42 143.2 0.0 4.3e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 EGD84098.1 - 0.018 14.9 0.0 0.023 14.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF3939 PF13075.6 EGD84098.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) Peptidase_M28 PF04389.17 EGD84100.1 - 1e-34 120.0 0.0 1.8e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 ATP-synt_8 PF00895.20 EGD84100.1 - 0.077 13.5 0.0 0.077 13.5 0.0 4.4 5 0 0 5 5 5 0 ATP synthase protein 8 Peptidase_M20 PF01546.28 EGD84100.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 LRR_6 PF13516.6 EGD84101.1 - 8.6e-13 47.2 21.6 0.35 11.0 0.0 12.5 13 0 0 13 13 13 3 Leucine Rich repeat LRR_4 PF12799.7 EGD84101.1 - 2e-09 37.6 13.3 2.7 8.5 0.0 7.8 3 2 3 8 8 8 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGD84101.1 - 6.3e-09 35.6 1.7 6.3e-09 35.6 1.7 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EGD84101.1 - 0.0027 17.5 9.1 0.0043 16.9 2.3 3.4 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.6 EGD84101.1 - 0.16 11.8 8.6 3.6 7.4 0.0 5.3 5 1 1 6 6 6 0 Leucine rich repeat AMP-binding PF00501.28 EGD84102.2 - 1e-31 110.0 0.1 1.3e-31 109.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD84102.2 - 1.6e-17 64.2 0.0 3.3e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_L13 PF00572.18 EGD84103.2 - 3.6e-11 43.4 0.0 3.1e-09 37.1 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 Metallophos PF00149.28 EGD84104.2 - 8e-15 55.9 0.6 1.2e-14 55.3 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGD84104.2 - 6.5e-07 29.7 0.5 1.7e-05 25.0 0.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EGD84104.2 - 4.7e-05 22.8 0.0 0.0089 15.4 0.0 2.5 2 1 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily MutL PF13941.6 EGD84104.2 - 0.027 13.1 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 MutL protein Pyr_redox_2 PF07992.14 EGD84105.1 - 2.9e-36 125.2 0.0 4e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGD84105.1 - 4.7e-15 55.9 0.0 6.5e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGD84105.1 - 4.1e-06 26.3 0.0 2.8e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGD84105.1 - 2e-05 23.9 0.0 0.00039 19.7 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EGD84105.1 - 0.00066 18.6 0.0 0.82 8.5 0.0 2.8 2 1 0 3 3 3 2 Tryptophan halogenase Eno-Rase_NADH_b PF12242.8 EGD84105.1 - 0.02 14.6 0.0 0.094 12.5 0.0 2.1 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.6 EGD84105.1 - 0.023 15.1 0.0 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EGD84105.1 - 0.026 14.5 0.3 79 3.2 0.0 3.8 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EGD84105.1 - 0.029 13.4 0.0 4.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 EGD84105.1 - 0.029 14.0 0.1 2.3 7.7 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1188 PF06690.11 EGD84105.1 - 0.058 12.9 0.0 0.48 9.9 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1188) DnaJ PF00226.31 EGD84108.1 - 4e-21 74.9 1.0 8.6e-21 73.8 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain PRP38_assoc PF12871.7 EGD84108.1 - 6.4e-05 23.5 32.0 6.4e-05 23.5 32.0 6.1 4 1 1 5 5 5 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Adaptin_N PF01602.20 EGD84110.1 - 4.6e-141 470.9 0.3 5.5e-141 470.7 0.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EGD84110.1 - 4.6e-21 75.2 0.0 1.1e-20 74.0 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.6 EGD84110.1 - 1e-08 35.4 0.5 0.0089 16.4 0.0 4.5 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EGD84110.1 - 1.3e-08 35.0 2.5 0.00022 21.3 0.0 4.0 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGD84110.1 - 0.00041 20.4 2.1 6.5 7.3 0.1 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 EGD84110.1 - 0.0037 17.7 0.2 22 5.7 0.0 4.8 4 1 0 4 4 4 0 HEAT-like repeat RICTOR_M PF14666.6 EGD84110.1 - 0.05 13.4 0.4 0.43 10.4 0.0 2.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Arm PF00514.23 EGD84110.1 - 0.092 12.8 0.1 99 3.2 0.1 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 EGD84110.1 - 0.16 12.3 0.2 0.55 10.6 0.2 2.0 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion EamA PF00892.20 EGD84112.1 - 9.8e-09 35.5 26.8 3.4e-05 24.0 3.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EGD84112.1 - 5.8e-08 32.3 0.1 1.1e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EGD84112.1 - 0.00011 21.6 8.0 0.00023 20.5 8.0 1.6 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 EGD84112.1 - 0.0019 17.6 6.7 0.0022 17.4 0.2 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family Med15_fungi PF05397.12 EGD84113.1 - 6.5e-26 90.8 0.1 6.5e-26 90.8 0.1 8.2 10 1 0 10 10 10 1 Mediator complex subunit 15 LMBR1 PF04791.16 EGD84114.1 - 1.7e-123 413.3 1.8 1.9e-123 413.1 1.8 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein BAG PF02179.16 EGD84115.1 - 5.3e-09 36.4 0.1 1.2e-08 35.2 0.1 1.6 1 0 0 1 1 1 1 BAG domain Collagen PF01391.18 EGD84116.1 - 2e-06 27.4 7.9 4.8e-06 26.2 7.9 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) ING PF12998.7 EGD84117.1 - 3.1e-07 30.9 0.0 6.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGD84117.1 - 2.7e-06 27.2 9.6 6.2e-06 26.0 9.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EGD84117.1 - 0.15 12.3 1.0 0.34 11.2 1.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 EGD84117.1 - 1.3 8.6 3.6 2.2 7.9 3.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-C2H2 PF00096.26 EGD84118.2 - 0.014 15.8 3.7 0.041 14.3 3.7 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD84118.2 - 0.61 11.1 3.3 1.9 9.5 3.3 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Methyltransf_16 PF10294.9 EGD84119.2 - 9.4e-07 28.7 0.0 6.8e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Lysine methyltransferase ABC_membrane PF00664.23 EGD84121.2 - 2.2e-42 145.6 12.5 2.8e-42 145.3 12.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGD84121.2 - 5e-18 65.9 0.0 8.2e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGD84121.2 - 0.00026 21.4 0.0 0.001 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 EGD84121.2 - 0.0021 17.8 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EGD84121.2 - 0.003 16.9 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 EGD84121.2 - 0.0072 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MeaB PF03308.16 EGD84121.2 - 0.014 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EGD84121.2 - 0.017 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 EGD84121.2 - 0.019 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGD84121.2 - 0.024 14.9 0.0 0.061 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EGD84121.2 - 0.029 14.1 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 EGD84121.2 - 0.036 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.6 EGD84121.2 - 0.062 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EGD84121.2 - 0.11 12.6 0.0 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 EGD84121.2 - 0.12 12.9 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGD84121.2 - 0.17 12.1 0.0 0.45 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain DSPc PF00782.20 EGD84123.2 - 5.3e-25 87.8 0.0 1.1e-21 77.0 0.0 2.3 1 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGD84123.2 - 0.057 13.0 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Pkinase PF00069.25 EGD84130.1 - 1.7e-09 37.5 0.0 1.9e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84130.1 - 0.093 12.0 0.1 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase DSBA PF01323.20 EGD84131.1 - 6.4e-35 120.7 0.0 7.2e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EGD84131.1 - 0.0045 17.2 0.1 0.023 14.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Epimerase PF01370.21 EGD84132.1 - 2.6e-16 59.8 0.0 4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGD84132.1 - 2.5e-14 52.9 0.0 3.3e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGD84132.1 - 2.4e-08 33.7 0.0 6.4e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGD84132.1 - 2.2e-07 30.3 0.0 4.7e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EGD84132.1 - 1.4e-06 28.3 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGD84132.1 - 2.3e-06 27.6 0.0 5.6e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGD84132.1 - 0.00093 18.4 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EGD84132.1 - 0.015 14.7 0.3 0.029 13.8 0.0 1.5 2 0 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.13 EGD84132.1 - 0.026 14.1 0.2 0.082 12.4 0.2 1.9 1 1 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 EGD84132.1 - 0.049 12.7 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain KH_1 PF00013.29 EGD84133.1 - 4.3e-41 138.6 9.0 6.3e-17 61.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGD84133.1 - 6.9e-10 38.6 8.2 0.0012 18.6 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGD84133.1 - 3.6e-09 36.4 2.8 0.025 14.5 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EGD84133.1 - 0.00091 19.3 6.8 0.29 11.3 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain ECF-ribofla_trS PF07155.12 EGD84133.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component Dehydratase_hem PF13816.6 EGD84134.1 - 3.8e-115 384.6 0.0 4.3e-115 384.4 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 EGD84134.1 - 5.2e-09 36.5 0.1 0.0007 19.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) ADH_zinc_N PF00107.26 EGD84135.2 - 5.1e-17 62.1 0.0 6.6e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGD84135.2 - 6.3e-06 25.8 0.0 8e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EGD84135.2 - 0.0099 15.2 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 EGD84135.2 - 0.12 13.4 0.0 0.15 13.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Yippee-Mis18 PF03226.14 EGD84136.1 - 2.6e-18 66.1 0.4 3e-18 66.0 0.4 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EGD84136.1 - 0.0015 18.7 2.4 0.0021 18.3 2.4 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I DUF2039 PF10217.9 EGD84136.1 - 0.0083 16.4 1.8 0.064 13.6 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) DUF4451 PF14616.6 EGD84136.1 - 0.0084 16.3 2.5 0.013 15.7 2.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) HNH_5 PF14279.6 EGD84136.1 - 0.031 14.1 1.1 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 HNH endonuclease Endonuclease_7 PF02945.15 EGD84136.1 - 0.038 13.9 2.3 0.077 12.9 2.3 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII Eapp_C PF10238.9 EGD84136.1 - 0.16 12.0 3.5 0.9 9.6 3.5 2.0 1 1 0 1 1 1 0 E2F-associated phosphoprotein Evr1_Alr PF04777.13 EGD84136.1 - 0.35 11.4 2.7 1.8 9.0 0.4 2.1 1 1 1 2 2 2 0 Erv1 / Alr family RabGAP-TBC PF00566.18 EGD84139.1 - 5.6e-31 107.9 1.9 1.4e-30 106.6 1.9 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 EGD84140.2 - 3.7e-55 187.1 0.0 5.5e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84140.2 - 7.7e-20 71.3 0.0 1.3e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGD84140.2 - 8.3e-05 21.7 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGD84140.2 - 8.8e-05 21.9 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGD84140.2 - 0.00039 20.4 0.1 0.0016 18.4 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGD84140.2 - 0.0058 15.4 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGD84140.2 - 0.006 16.2 0.3 0.014 15.0 0.3 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGD84140.2 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase LRR_6 PF13516.6 EGD84141.1 - 9.4e-14 50.2 13.7 0.0032 17.4 0.1 7.2 7 0 0 7 7 7 5 Leucine Rich repeat F-box-like PF12937.7 EGD84141.1 - 1.5e-09 37.6 0.1 4.5e-09 36.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD84141.1 - 4e-09 36.1 0.5 1.2e-08 34.7 0.5 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EGD84141.1 - 4.1e-06 27.0 19.9 0.00014 22.2 1.2 5.3 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGD84141.1 - 0.0078 16.6 20.1 1.4 9.7 0.4 7.3 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 EGD84141.1 - 0.022 14.5 0.8 20 5.0 0.1 3.9 3 1 1 4 4 4 0 Leucine rich repeat PRANC PF09372.10 EGD84141.1 - 0.096 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 PRANC domain Efg1 PF10153.9 EGD84142.1 - 2e-32 111.9 12.1 2e-32 111.9 12.1 2.6 3 0 0 3 3 3 1 rRNA-processing protein Efg1 DUF573 PF04504.14 EGD84142.1 - 0.029 15.0 2.1 0.029 15.0 2.1 3.2 2 1 0 3 3 3 0 Protein of unknown function, DUF573 Lactonase PF10282.9 EGD84143.2 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PTS_2-RNA PF01885.16 EGD84144.1 - 2.3e-63 213.5 0.0 2.8e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family APH PF01636.23 EGD84145.2 - 2.4e-14 53.9 0.0 2.6e-13 50.5 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGD84145.2 - 0.12 11.2 0.0 0.28 10.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) p450 PF00067.22 EGD84146.2 - 6.9e-56 189.9 0.0 9e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Stb3 PF10330.9 EGD84149.1 - 2.5e-37 126.8 0.0 4.1e-37 126.1 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Mito_carr PF00153.27 EGD84152.1 - 1.8e-67 223.3 6.0 6.7e-25 86.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Kri1 PF05178.12 EGD84154.1 - 9.2e-31 106.5 18.7 9.2e-31 106.5 18.7 5.5 5 1 0 5 5 5 1 KRI1-like family Kri1_C PF12936.7 EGD84154.1 - 4.8e-29 100.4 0.1 4.8e-29 100.4 0.1 4.1 3 2 2 5 5 5 1 KRI1-like family C-terminal VASt PF16016.5 EGD84155.2 - 1.3e-36 126.3 0.6 3.4e-36 125.0 0.2 1.9 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 EGD84155.2 - 6.4e-11 42.4 0.1 2e-10 40.8 0.1 1.7 1 1 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EGD84155.2 - 1.1e-07 32.3 0.0 4.5e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 PH domain GRAM PF02893.20 EGD84155.2 - 0.00094 19.1 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Sen15 PF09631.10 EGD84156.1 - 4.2e-15 55.9 0.0 1.7e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 Sen15 protein 4HBT_3 PF13622.6 EGD84156.1 - 0.088 13.0 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily UAA PF08449.11 EGD84157.1 - 1.1e-43 149.6 12.5 3.2e-43 148.0 12.5 1.7 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EGD84157.1 - 1.1e-07 31.4 0.2 0.00058 19.1 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 EGD84157.1 - 5.3e-05 23.4 32.9 0.00071 19.8 12.0 3.7 3 1 0 3 3 3 2 EamA-like transporter family Rotamase_3 PF13616.6 EGD84158.2 - 0.00011 22.7 0.4 0.00024 21.6 0.4 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EGD84158.2 - 0.018 16.0 0.1 0.029 15.3 0.1 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain Rax2 PF12768.7 EGD84159.1 - 0.023 14.2 0.1 0.032 13.7 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 EGD84159.1 - 0.21 11.0 1.8 0.61 9.5 1.8 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain 2OG-FeII_Oxy_2 PF13532.6 EGD84160.2 - 0.0027 17.9 0.0 0.0031 17.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Steroid_dh PF02544.16 EGD84161.1 - 2.1e-10 40.8 2.0 2.1e-10 40.8 2.0 2.2 1 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ank_2 PF12796.7 EGD84162.1 - 2.6e-24 85.6 0.2 1.2e-12 48.2 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGD84162.1 - 2.4e-20 72.3 0.8 1.7e-09 37.8 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGD84162.1 - 1.9e-14 53.8 0.0 3.1e-07 30.8 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGD84162.1 - 1.6e-13 50.4 0.8 0.0011 19.3 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EGD84162.1 - 7.3e-12 44.4 0.7 0.00015 21.9 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Vac_ImportDeg PF09783.9 EGD84164.1 - 1.3e-39 135.6 0.1 3.6e-39 134.2 0.0 1.7 2 0 0 2 2 2 1 Vacuolar import and degradation protein MR_MLE_C PF13378.6 EGD84166.1 - 1.3e-55 188.4 0.0 1.7e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGD84166.1 - 1.8e-17 63.6 0.0 4e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF4213 PF13938.6 EGD84166.1 - 0.052 13.8 0.0 1.3 9.3 0.0 2.7 2 1 0 2 2 2 0 Putative heavy-metal chelation IU_nuc_hydro PF01156.19 EGD84167.2 - 2.2e-43 149.0 0.0 2.5e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PXA PF02194.15 EGD84168.2 - 4.1e-18 66.0 0.0 6.6e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 PXA domain MMR_HSR1_Xtn PF16897.5 EGD84172.2 - 8.5e-40 135.1 0.6 2.8e-39 133.4 0.3 1.9 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EGD84172.2 - 1.6e-19 69.7 0.0 3e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EGD84172.2 - 0.00029 20.9 0.0 0.0011 19.1 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase CDO_I PF05995.12 EGD84173.1 - 4.2e-40 136.8 0.0 5.1e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EGD84173.1 - 3.2e-08 33.3 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO Glyco_transf_90 PF05686.12 EGD84175.1 - 1.5e-15 57.1 9.8 1.8e-12 46.9 7.2 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_6 PF12697.7 EGD84176.1 - 4.7e-15 56.8 1.2 3.9e-14 53.8 1.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGD84176.1 - 8.1e-11 42.0 0.0 3.7e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD84176.1 - 0.00025 20.4 0.0 0.00035 19.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 EGD84176.1 - 0.0041 17.5 0.2 0.0083 16.5 0.2 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_2 PF02230.16 EGD84176.1 - 0.018 14.8 0.0 7.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Med10 PF09748.9 EGD84176.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex HEAT PF02985.22 EGD84178.2 - 2.3e-43 142.5 9.5 0.014 15.6 0.1 12.4 12 0 0 12 12 12 11 HEAT repeat HEAT_2 PF13646.6 EGD84178.2 - 1.1e-34 118.7 1.1 8.6e-10 38.9 0.0 7.6 4 1 2 7 7 7 7 HEAT repeats HEAT_EZ PF13513.6 EGD84178.2 - 4.5e-16 59.0 4.1 5.5e-05 23.6 0.0 8.5 7 2 2 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGD84178.2 - 6.6e-12 45.9 3.6 0.00048 20.7 0.2 7.2 5 2 4 9 9 9 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGD84178.2 - 7.3e-12 45.6 7.8 0.0022 18.1 0.3 5.8 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGD84178.2 - 1.8e-08 33.4 4.9 4.9e-07 28.7 1.4 3.4 2 1 1 3 3 3 1 Adaptin N terminal region RTP1_C1 PF10363.9 EGD84178.2 - 0.0013 18.9 3.8 0.9 9.7 0.3 4.1 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EGD84178.2 - 0.015 14.9 4.0 2.1 7.8 0.4 4.5 4 2 1 5 5 5 0 CLASP N terminal TetR_C_16 PF17920.1 EGD84178.2 - 0.076 13.3 0.5 17 5.7 0.0 3.5 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain M11L PF11099.8 EGD84178.2 - 0.14 12.4 0.2 52 4.1 0.0 3.3 2 1 1 3 3 3 0 Apoptosis regulator M11L like IFRD PF05004.13 EGD84178.2 - 0.19 10.8 0.5 2.2 7.3 0.0 2.8 2 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Ecm29 PF13001.7 EGD84178.2 - 0.22 10.1 2.4 13 4.4 0.1 3.4 3 1 1 4 4 4 0 Proteasome stabiliser Arm PF00514.23 EGD84178.2 - 0.36 10.9 7.2 1.8 8.7 0.0 4.8 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat API5 PF05918.11 EGD84178.2 - 0.89 8.3 5.2 0.77 8.5 1.6 2.7 3 1 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) tRNA_synthFbeta PF17759.1 EGD84180.1 - 3.4e-49 167.2 0.0 4.9e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EGD84180.1 - 4e-29 100.7 0.2 5e-28 97.2 0.1 2.2 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EGD84180.1 - 9.8e-25 87.2 0.1 1.9e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EGD84180.1 - 1.5e-18 66.9 0.0 2e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2740 PF10872.8 EGD84180.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Ribosomal_S3_C PF00189.20 EGD84181.1 - 3.7e-25 88.3 0.1 2e-24 85.9 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EGD84181.1 - 6.5e-12 45.1 0.1 1.2e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 EGD84181.1 - 0.036 13.9 0.1 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Coilin N-terminus UN_NPL4 PF11543.8 EGD84181.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.14 EGD84182.1 - 4.5e-150 499.5 0.0 5.5e-150 499.2 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EGD84182.1 - 0.0012 18.9 0.2 0.0038 17.2 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGD84182.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SLS PF14611.6 EGD84183.1 - 2.4e-34 119.1 0.2 4e-34 118.4 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator EcoEI_R_C PF08463.10 EGD84183.1 - 0.015 15.4 0.2 0.034 14.2 0.2 1.5 1 0 0 1 1 1 0 EcoEI R protein C-terminal NT-C2 PF10358.9 EGD84184.2 - 5.4e-28 97.5 0.0 7.1e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins p450 PF00067.22 EGD84185.1 - 2.3e-31 109.1 0.0 3.2e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGD84186.2 - 4.3e-34 118.1 0.0 6.2e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Mgr1 PF08602.10 EGD84187.1 - 0.061 12.1 2.4 0.077 11.8 2.4 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Seryl_tRNA_N PF02403.22 EGD84187.1 - 0.43 10.8 12.8 0.3 11.3 11.4 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HAUS6_N PF14661.6 EGD84187.1 - 1.9 8.0 11.3 2.6 7.5 11.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Coiled-coil_56 PF09813.9 EGD84187.1 - 6.6 6.8 11.1 3.7 7.7 9.0 1.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 Atg14 PF10186.9 EGD84187.1 - 8.7 5.3 11.4 12 4.9 11.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SF3b10 PF07189.11 EGD84192.1 - 4.6e-34 116.4 0.0 5.1e-34 116.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) A_deamin PF02137.18 EGD84194.2 - 2e-09 37.4 0.0 1.2e-07 31.5 0.0 2.1 1 1 1 2 2 2 2 Adenosine-deaminase (editase) domain ERG4_ERG24 PF01222.17 EGD84195.1 - 1.7e-148 494.9 0.8 2e-148 494.7 0.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGD84195.1 - 0.00021 20.9 0.5 0.00053 19.6 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Ferlin_C PF16165.5 EGD84195.1 - 3.3 7.6 4.1 0.81 9.6 0.3 1.9 2 0 0 2 2 2 0 Ferlin C-terminus Man-6-P_recep PF02157.15 EGD84196.2 - 1.4e-11 43.9 0.0 4.7e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EGD84196.2 - 2.2e-08 34.3 0.1 3.3e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 EGD84196.2 - 5.7e-07 29.7 0.2 0.00012 22.2 0.0 2.5 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat CDC45 PF02724.14 EGD84196.2 - 7.1 4.8 6.5 10 4.3 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EGD84196.2 - 7.3 5.8 10.4 3.8 6.7 7.9 1.6 2 0 0 2 2 2 0 NOA36 protein Fungal_trans PF04082.18 EGD84197.2 - 1.4e-24 86.6 0.6 6.9e-24 84.3 0.0 2.5 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD84197.2 - 3.2e-06 27.2 8.1 5.7e-06 26.4 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 EGD84197.2 - 0.001 19.2 16.9 0.001 19.2 16.9 2.6 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 EGD84197.2 - 0.21 11.7 15.3 0.25 11.5 7.2 2.3 2 0 0 2 2 2 0 DDHD domain DUF2202 PF09968.9 EGD84197.2 - 0.39 10.6 4.1 0.84 9.5 4.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) Spt20 PF12090.8 EGD84197.2 - 0.48 10.0 50.9 0.077 12.6 27.4 2.5 2 0 0 2 2 2 0 Spt20 family PBP1_TM PF14812.6 EGD84197.2 - 1.2 9.6 3.5 35 4.8 2.9 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAT1 PF09770.9 EGD84197.2 - 3.4 5.8 38.1 1.8 6.7 12.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SKG6 PF08693.10 EGD84199.2 - 0.0011 18.3 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4381 PF14316.6 EGD84199.2 - 0.06 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CcmD PF04995.14 EGD84199.2 - 0.42 10.7 3.6 0.59 10.3 0.1 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Glyco_hydro_47 PF01532.20 EGD84200.1 - 3.1e-181 603.3 0.0 3.6e-181 603.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 EGD84200.1 - 0.00052 18.6 0.0 0.064 11.7 0.0 2.2 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_3_C PF01915.22 EGD84201.1 - 3.8e-52 177.2 0.0 7e-52 176.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGD84201.1 - 2.2e-37 129.1 0.0 4.5e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGD84201.1 - 2.3e-12 46.9 0.0 4.4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain APH PF01636.23 EGD84204.2 - 0.03 14.3 0.7 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Zn_clus PF00172.18 EGD84207.1 - 0.0069 16.5 12.3 0.013 15.6 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Scs3p PF10261.9 EGD84208.1 - 8e-69 231.9 1.9 1.1e-68 231.4 1.9 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Erythro_esteras PF05139.14 EGD84210.1 - 3.7e-125 418.3 2.4 4.3e-125 418.1 2.4 1.0 1 0 0 1 1 1 1 Erythromycin esterase Cofac_haem_bdg PF04187.13 EGD84210.1 - 0.00055 20.0 0.3 0.58 10.1 0.1 2.3 2 0 0 2 2 2 2 Haem-binding uptake, Tiki superfamily, ChaN DUF3535 PF12054.8 EGD84212.2 - 2.7e-127 425.6 0.0 4.2e-126 421.7 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EGD84212.2 - 8.5e-64 215.5 0.0 2.3e-63 214.0 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGD84212.2 - 1.8e-19 70.1 0.0 5.9e-19 68.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EGD84212.2 - 9.8e-18 62.7 9.1 0.0014 18.7 0.2 9.6 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.6 EGD84212.2 - 2.2e-06 28.0 6.8 0.0022 18.3 0.2 6.3 6 1 0 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EGD84212.2 - 7.3e-06 26.5 0.1 0.56 10.8 0.0 4.2 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGD84212.2 - 0.00045 19.9 0.0 0.11 12.0 0.0 3.7 3 1 1 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 EGD84212.2 - 0.0013 19.2 8.1 7.6 7.2 0.0 7.1 6 1 2 8 8 8 1 HEAT-like repeat TAF6_C PF07571.13 EGD84212.2 - 0.0023 18.2 0.1 0.35 11.2 0.0 4.4 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain RTP1_C1 PF10363.9 EGD84212.2 - 0.039 14.1 0.0 0.8 9.9 0.0 3.3 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Ndufs5 PF10200.9 EGD84213.1 - 0.00065 19.9 0.0 0.00073 19.7 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.17 EGD84213.1 - 0.007 16.6 0.2 0.01 16.0 0.2 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DnaJ PF00226.31 EGD84213.1 - 0.021 14.9 0.3 0.029 14.5 0.3 1.2 1 0 0 1 1 1 0 DnaJ domain DUF3128 PF11326.8 EGD84213.1 - 0.055 13.8 1.6 0.35 11.2 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) UPF0203 PF05254.12 EGD84213.1 - 0.062 13.6 0.1 0.094 13.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) Sec39 PF08314.11 EGD84214.2 - 3.6e-145 485.4 0.0 4.3e-145 485.1 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 CN_hydrolase PF00795.22 EGD84217.1 - 2.5e-36 125.4 0.0 3.5e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EGD84217.1 - 3.7e-25 88.5 0.0 7.7e-25 87.4 0.0 1.5 1 1 0 1 1 1 1 NAD synthase Protoglobin PF11563.8 EGD84218.1 - 1.7e-51 174.2 0.0 2e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Protoglobin DUF87 PF01935.17 EGD84225.2 - 0.0012 19.0 2.0 0.0016 18.6 2.0 1.2 1 0 0 1 1 1 1 Helicase HerA, central domain HMMR_N PF15905.5 EGD84225.2 - 0.0037 16.8 12.9 0.0046 16.5 12.9 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Penicil_amidase PF01804.18 EGD84225.2 - 0.0063 15.5 0.7 0.0069 15.4 0.7 1.0 1 0 0 1 1 1 1 Penicillin amidase FOXP-CC PF16159.5 EGD84225.2 - 0.043 14.5 2.3 0.063 13.9 0.1 2.3 2 1 0 2 2 2 0 FOXP coiled-coil domain Exonuc_VII_L PF02601.15 EGD84225.2 - 0.31 10.6 9.0 0.39 10.2 9.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit BCAS2 PF05700.11 EGD84225.2 - 0.34 10.6 13.9 1.1 9.0 13.8 1.7 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) Fib_alpha PF08702.10 EGD84225.2 - 0.37 11.0 14.6 0.1 12.8 4.0 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 EGD84225.2 - 0.47 8.9 2.0 0.55 8.7 2.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 EGD84225.2 - 0.56 9.5 12.0 0.81 8.9 12.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ACCA PF03255.14 EGD84225.2 - 0.99 9.3 8.2 10 6.0 2.8 2.5 1 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit NPV_P10 PF05531.12 EGD84225.2 - 1.1 9.8 12.7 2 9.0 4.5 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Jnk-SapK_ap_N PF09744.9 EGD84225.2 - 1.2 9.4 15.0 1.3 9.3 12.3 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CENP-Q PF13094.6 EGD84225.2 - 2.9 8.0 13.6 6.3 7.0 13.6 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF16 PF01519.16 EGD84225.2 - 5.9 7.4 13.2 76 3.9 13.2 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 LMBR1 PF04791.16 EGD84225.2 - 6.3 5.6 6.5 8.6 5.1 6.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-CRD PF17979.1 EGD84225.2 - 8 6.5 7.0 8.7 6.4 1.2 2.4 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions Csm1_N PF18504.1 EGD84225.2 - 9.3 6.7 16.6 0.42 11.0 1.9 3.1 1 1 2 3 3 3 0 Csm1 N-terminal domain Phospholip_B PF04916.13 EGD84227.2 - 0.02 13.5 0.0 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 Phospholipase B Aurora-A_bind PF09041.10 EGD84228.1 - 0.03 14.4 1.3 1.7 8.7 0.3 3.0 1 1 2 3 3 3 0 Aurora-A binding CdvA PF18822.1 EGD84230.1 - 0.00079 19.3 1.0 0.002 18.0 0.1 2.1 3 0 0 3 3 3 1 CdvA-like coiled-coil domain zf-C2H2_4 PF13894.6 EGD84232.2 - 9.9 7.3 17.6 5.3 8.2 2.0 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger B5 PF03484.15 EGD84234.1 - 0.12 12.6 0.0 0.27 11.6 0.0 1.7 1 1 0 1 1 1 0 tRNA synthetase B5 domain DUF4451 PF14616.6 EGD84238.1 - 6.2e-22 78.1 0.2 1.1e-21 77.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Dynamin_N PF00350.23 EGD84239.2 - 3.8e-18 66.1 0.0 4.8e-17 62.5 0.0 2.9 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EGD84239.2 - 9.9e-08 32.1 0.2 2.4e-06 27.6 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGD84239.2 - 0.00025 21.6 0.4 0.00088 19.8 0.0 2.3 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EGD84239.2 - 0.00099 19.0 1.4 0.0042 17.0 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 EGD84239.2 - 0.0037 16.6 1.3 0.045 13.1 0.1 2.9 3 0 0 3 3 3 1 AIG1 family IIGP PF05049.13 EGD84239.2 - 0.0037 16.4 0.0 0.015 14.4 0.0 2.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 EGD84239.2 - 0.038 13.3 2.2 1.2 8.4 0.1 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family Mei5_like PF17021.5 EGD84239.2 - 0.06 13.4 2.4 3.3 7.8 1.7 2.8 2 0 0 2 2 2 0 Putative double-strand recombination repair-like Pkinase PF00069.25 EGD84243.1 - 9e-39 133.4 0.0 1.3e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84243.1 - 9.6e-26 90.6 0.0 1.4e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGD84243.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGD84243.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Ras PF00071.22 EGD84244.1 - 1.2e-54 184.2 0.0 1.6e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD84244.1 - 5.9e-34 116.9 0.0 8.3e-34 116.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD84244.1 - 1.1e-12 47.8 0.0 1.7e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGD84244.1 - 0.00018 21.1 0.0 0.00028 20.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGD84244.1 - 0.00029 20.9 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGD84244.1 - 0.00034 20.1 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EGD84244.1 - 0.0015 18.9 0.0 0.0028 18.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Acetate_kinase PF00871.17 EGD84247.1 - 5.3e-85 285.5 0.0 4.8e-84 282.3 0.0 1.9 1 1 0 1 1 1 1 Acetokinase family MCM6_C PF18263.1 EGD84247.1 - 0.076 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Ribosomal_S7e PF01251.18 EGD84249.1 - 1.9e-79 265.7 0.2 2.2e-79 265.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Vezatin PF12632.7 EGD84249.1 - 0.018 14.4 0.7 2.1 7.6 0.0 2.0 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes EntA_Immun PF08951.10 EGD84249.1 - 0.041 14.2 0.1 0.09 13.1 0.1 1.5 1 0 0 1 1 1 0 Enterocin A Immunity Dynactin_p62 PF05502.13 EGD84250.1 - 3.3e-207 689.0 0.1 4e-207 688.7 0.1 1.0 1 0 0 1 1 1 1 Dynactin p62 family Methyltransf_23 PF13489.6 EGD84251.2 - 0.0044 16.9 0.0 0.0058 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain P16-Arc PF04699.14 EGD84252.1 - 2e-46 158.2 0.0 2.3e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Cation_ATPase_C PF00689.21 EGD84253.2 - 2e-47 161.2 7.6 3.5e-47 160.4 7.6 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGD84253.2 - 9.3e-21 73.7 0.0 2e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGD84253.2 - 1.7e-16 61.2 2.1 1.1e-15 58.5 2.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGD84253.2 - 2.9e-05 23.9 0.0 0.00071 19.4 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GFO_IDH_MocA PF01408.22 EGD84254.2 - 1.4e-09 38.8 0.3 5.7e-09 36.8 0.3 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.22 EGD84255.1 - 2.8e-32 111.6 0.0 1.1e-30 106.4 0.0 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family ADH_N PF08240.12 EGD84256.1 - 8.1e-26 90.0 4.4 1.4e-25 89.3 4.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGD84256.1 - 3.3e-16 59.5 0.1 2.4e-15 56.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGD84256.1 - 0.00017 21.0 0.2 0.00032 20.1 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.32 EGD84257.2 - 3.4e-26 91.0 13.8 3.4e-06 27.7 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ PF01011.21 EGD84257.2 - 3.5e-06 26.7 0.0 0.8 9.7 0.0 3.8 3 0 0 3 3 3 2 PQQ enzyme repeat F-box-like PF12937.7 EGD84257.2 - 6.9e-06 25.9 0.2 1.5e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.6 EGD84257.2 - 3.6e-05 23.4 0.1 0.15 11.6 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain ANAPC4_WD40 PF12894.7 EGD84257.2 - 9.9e-05 22.6 1.5 4.1 7.8 0.0 4.9 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGD84257.2 - 0.002 18.1 0.2 18 5.5 0.1 4.3 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region F-box PF00646.33 EGD84257.2 - 0.0066 16.3 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain STE PF02200.16 EGD84257.2 - 0.019 15.4 0.1 0.61 10.5 0.0 2.5 2 0 0 2 2 2 0 STE like transcription factor PALB2_WD40 PF16756.5 EGD84257.2 - 0.029 13.3 0.1 2.4 7.0 0.0 2.4 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain DUF5046 PF16465.5 EGD84257.2 - 0.031 13.7 0.2 0.82 9.1 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5046) Nup160 PF11715.8 EGD84257.2 - 0.049 12.3 0.5 12 4.5 0.0 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EGD84257.2 - 0.17 12.4 1.9 55 4.4 0.0 4.4 5 0 0 5 5 5 0 PQQ-like domain ADH_zinc_N_2 PF13602.6 EGD84258.1 - 1.4e-13 52.0 0.0 2.3e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGD84258.1 - 2.5e-08 34.0 0.0 5.6e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase EB1 PF03271.17 EGD84259.1 - 3.5e-17 62.3 1.7 6.6e-17 61.5 1.7 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EGD84259.1 - 2.1e-06 27.9 0.4 5.8e-06 26.5 0.5 1.7 1 1 1 2 2 2 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 EGD84259.1 - 0.00062 18.4 0.0 0.00087 17.9 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like CH_2 PF06294.11 EGD84259.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 CH-like domain in sperm protein Macoilin PF09726.9 EGD84261.2 - 0.48 8.9 11.2 0.66 8.5 11.2 1.1 1 0 0 1 1 1 0 Macoilin family Glutaredoxin PF00462.24 EGD84264.1 - 2.1e-20 72.7 0.1 3e-20 72.2 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EGD84264.1 - 0.005 17.2 0.0 0.0061 17.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 EGD84264.1 - 0.015 15.8 0.1 0.019 15.4 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.14 EGD84264.1 - 0.022 15.2 0.0 0.028 14.8 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GTP_EFTU PF00009.27 EGD84266.1 - 1.4e-54 184.6 0.0 2.1e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGD84266.1 - 4.4e-42 142.9 0.0 1e-41 141.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGD84266.1 - 9.9e-15 54.7 1.4 3.1e-14 53.1 1.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGD84266.1 - 0.0012 18.9 0.2 0.013 15.6 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EGD84266.1 - 0.0091 15.9 1.2 0.027 14.4 1.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 TFIIS_C PF01096.18 EGD84267.1 - 9.8e-19 66.9 2.3 9.8e-19 66.9 2.3 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGD84267.1 - 8.6e-06 25.5 9.9 0.0002 21.1 5.3 3.4 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EGD84267.1 - 0.0065 16.4 6.7 0.12 12.3 1.3 2.5 2 0 0 2 2 2 2 Transposase zinc-ribbon domain C1_4 PF07975.12 EGD84267.1 - 0.098 12.9 4.9 1.4 9.2 0.3 2.6 2 2 0 2 2 2 0 TFIIH C1-like domain zf-Mss51 PF13824.6 EGD84267.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.0 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-H2C2_2 PF13465.6 EGD84267.1 - 2.7 8.6 12.4 3.9 8.1 0.3 3.6 4 0 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_4 PF13717.6 EGD84267.1 - 3.1 7.8 10.8 15 5.6 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Rubredoxin PF00301.20 EGD84267.1 - 4.3 7.4 8.1 8.6 6.5 0.2 3.4 3 0 0 3 3 3 0 Rubredoxin NAD_binding_10 PF13460.6 EGD84268.1 - 4.2e-09 36.5 0.0 8.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGD84268.1 - 4.5e-06 26.4 0.0 9.8e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EGD84268.1 - 0.027 13.9 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EGD84268.1 - 0.16 12.6 0.0 0.77 10.4 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 EGD84268.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain PH_4 PF15404.6 EGD84269.2 - 1.6e-54 184.5 1.0 1.6e-54 184.5 1.0 2.9 3 1 0 3 3 3 1 Pleckstrin homology domain Spo7_2_N PF15407.6 EGD84269.2 - 3.7e-15 55.3 0.1 9.7e-15 54.0 0.1 1.8 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 EGD84269.2 - 1.9e-10 41.1 0.3 0.011 16.2 0.0 5.5 4 1 0 4 4 4 2 PH domain PH_6 PF15406.6 EGD84269.2 - 0.0011 19.3 0.1 0.14 12.4 0.1 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 EGD84269.2 - 0.029 14.7 0.0 0.57 10.6 0.0 3.0 4 0 0 4 4 4 0 Pleckstrin homology domain PH_13 PF16652.5 EGD84269.2 - 0.049 13.4 0.2 7.1 6.4 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain GLTP PF08718.11 EGD84270.1 - 2.1e-47 161.1 0.1 2.7e-47 160.8 0.1 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) AA_permease_2 PF13520.6 EGD84271.2 - 4.8e-63 213.5 50.5 5.8e-63 213.2 50.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD84271.2 - 1.7e-20 73.1 40.6 1.9e-20 72.9 40.1 1.3 1 1 0 1 1 1 1 Amino acid permease E1-E2_ATPase PF00122.20 EGD84274.2 - 1.9e-19 69.9 0.0 4.7e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGD84274.2 - 4e-13 50.1 1.2 4.4e-06 27.1 2.8 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGD84274.2 - 0.0038 17.0 0.2 0.028 14.2 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGD84274.2 - 0.0058 16.7 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) S6PP PF05116.13 EGD84274.2 - 0.11 11.9 1.1 0.29 10.6 0.0 2.1 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Rbsn PF11464.8 EGD84275.2 - 1e-17 63.6 0.6 2e-17 62.6 0.6 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE PF01363.21 EGD84275.2 - 4.1e-17 62.1 4.9 6.7e-17 61.4 4.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger YqaH PF17448.2 EGD84275.2 - 0.011 16.1 0.2 0.022 15.1 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized YqaH-like TMF_TATA_bd PF12325.8 EGD84275.2 - 0.036 14.3 0.5 0.036 14.3 0.5 1.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FYVE_2 PF02318.16 EGD84275.2 - 0.041 14.1 5.8 0.33 11.2 6.1 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger Seryl_tRNA_N PF02403.22 EGD84275.2 - 0.042 14.1 1.4 0.12 12.6 1.4 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain C6_DPF PF10170.9 EGD84275.2 - 0.057 13.8 0.3 0.15 12.5 0.3 1.6 1 0 0 1 1 1 0 Cysteine-rich domain DDE_Tnp_Tn3 PF01526.17 EGD84275.2 - 0.078 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Tn3 transposase DDE domain RE_BstXI PF09552.10 EGD84275.2 - 0.083 12.1 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease Nairovirus_M PF07948.11 EGD84275.2 - 0.19 9.9 0.6 0.34 9.1 0.3 1.4 1 1 1 2 2 2 0 Nairovirus M polyprotein-like Val_tRNA-synt_C PF10458.9 EGD84275.2 - 0.24 11.7 1.4 34 4.8 0.1 2.9 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm PKD_channel PF08016.12 EGD84276.2 - 2.1e-08 33.3 19.1 1.6e-07 30.4 15.9 2.4 1 1 0 1 1 1 1 Polycystin cation channel EIF_2_alpha PF07541.12 EGD84277.1 - 1.8e-36 124.7 0.0 3.9e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EGD84277.1 - 1.5e-13 50.8 0.9 3e-13 49.9 0.9 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Myb_DNA-bind_2 PF08914.11 EGD84277.1 - 0.15 12.2 0.1 0.39 10.9 0.1 1.7 1 0 0 1 1 1 0 Rap1 Myb domain Sulfate_transp PF00916.20 EGD84278.2 - 5.1e-72 242.7 14.2 9.3e-72 241.9 14.2 1.4 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGD84278.2 - 2.3e-15 56.2 0.0 3.9e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EGD84278.2 - 0.0055 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGD84278.2 - 3.8 8.0 16.1 0.049 14.0 4.4 2.9 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily CENP-L PF13092.6 EGD84279.1 - 1.6e-50 171.5 0.1 2.2e-50 171.1 0.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Cue1_U7BR PF18499.1 EGD84279.1 - 0.13 12.3 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 Acetyltransf_1 PF00583.25 EGD84281.1 - 2.3e-07 31.1 0.0 3.3e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGD84281.1 - 7.5e-07 29.5 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGD84281.1 - 7.4e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD84281.1 - 0.0086 16.0 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGD84281.1 - 0.031 14.4 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Trypan_PARP PF05887.11 EGD84284.1 - 2.1 8.3 16.0 0.62 10.0 12.5 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF3328 PF11807.8 EGD84285.1 - 3.1e-44 151.4 0.2 4.2e-44 150.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) R2K_2 PF18299.1 EGD84285.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 KTI12 PF08433.10 EGD84286.2 - 3.8e-26 92.2 0.0 1.5e-25 90.2 0.0 2.0 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Atg8 PF02991.16 EGD84288.1 - 5e-32 110.2 0.0 5.9e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Methyltransf_16 PF10294.9 EGD84290.2 - 5.4e-13 49.0 0.0 7.2e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGD84290.2 - 0.00014 21.7 0.0 0.00019 21.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EGD84290.2 - 0.0028 17.0 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.17 EGD84290.2 - 0.045 12.9 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family PrmA PF06325.13 EGD84290.2 - 0.047 13.1 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3403 PF11883.8 EGD84290.2 - 0.17 12.0 0.2 0.38 10.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3403) MFS_1 PF07690.16 EGD84292.2 - 4e-28 98.3 30.0 2.2e-25 89.3 19.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD84292.2 - 5.8e-05 22.1 6.8 5.8e-05 22.1 6.8 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EGD84292.2 - 0.00033 20.1 18.0 0.014 14.7 3.0 3.0 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EGD84292.2 - 0.55 9.0 13.3 0.017 14.0 3.0 2.8 2 2 0 2 2 2 0 MFS_1 like family DUF2070 PF09843.9 EGD84292.2 - 2.2 6.5 14.5 0.086 11.1 2.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) F-box PF00646.33 EGD84293.1 - 0.003 17.4 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGD84293.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 F-box-like AlaDh_PNT_N PF05222.15 EGD84294.1 - 5.7e-28 97.9 0.0 8.7e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EGD84294.1 - 0.0052 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain BAR PF03114.18 EGD84295.2 - 1.2e-66 224.8 7.7 1.5e-66 224.4 7.7 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EGD84295.2 - 7.4e-13 47.9 0.0 1.5e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGD84295.2 - 4.3e-08 32.9 0.0 8.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGD84295.2 - 1.8e-05 24.3 0.1 5.3e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.10 EGD84295.2 - 0.11 12.0 5.4 3.3 7.2 2.2 2.2 2 0 0 2 2 2 0 Vps5 C terminal like BAR_3 PF16746.5 EGD84295.2 - 0.43 10.3 9.9 1.8 8.2 9.9 2.2 1 1 0 1 1 1 0 BAR domain of APPL family TMPIT PF07851.13 EGD84295.2 - 0.77 8.9 8.7 1.2 8.3 0.2 2.1 1 1 1 2 2 2 0 TMPIT-like protein Peptidase_S46 PF10459.9 EGD84295.2 - 1.7 7.2 6.0 3.6 6.1 5.9 1.4 1 1 0 1 1 1 0 Peptidase S46 APG6_N PF17675.1 EGD84295.2 - 2.7 8.5 10.8 12 6.4 5.0 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 EGD84295.2 - 3.3 7.9 12.1 0.99 9.5 0.6 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase GST_N_3 PF13417.6 EGD84297.1 - 1.3e-17 64.0 0.1 3.1e-17 62.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGD84297.1 - 2.1e-17 63.2 0.0 3.7e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGD84297.1 - 2.9e-11 43.5 0.0 6.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGD84297.1 - 6.9e-06 26.2 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain motB PF17613.2 EGD84297.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Modifier of transcription ERG4_ERG24 PF01222.17 EGD84298.2 - 3.4e-14 52.4 0.3 4.2e-14 52.1 0.3 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ATP_transf PF09830.9 EGD84300.1 - 4.3e-15 55.6 0.1 4.3e-15 55.6 0.1 1.7 2 0 0 2 2 2 1 ATP adenylyltransferase Copper-bind PF00127.20 EGD84301.1 - 0.00047 20.5 0.1 0.00083 19.8 0.1 1.4 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family LEA_6 PF10714.9 EGD84301.1 - 0.00087 19.3 1.5 0.0014 18.6 1.5 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein 18 Cas_csx3 PF09620.10 EGD84301.1 - 0.018 14.9 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Cupredoxin_1 PF13473.6 EGD84301.1 - 0.1 12.7 0.2 0.39 10.9 0.2 1.9 1 1 0 1 1 1 0 Cupredoxin-like domain Aminotran_5 PF00266.19 EGD84302.1 - 3.5e-94 315.8 0.0 4.1e-94 315.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGD84302.1 - 6.1e-07 29.0 0.0 9.4e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGD84302.1 - 6.3e-06 25.7 0.1 3.4e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EGD84302.1 - 0.013 14.3 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 EGD84302.1 - 0.06 11.9 0.0 0.088 11.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IDO PF01231.18 EGD84303.1 - 4.1e-153 510.2 0.0 4.8e-153 510.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.13 EGD84304.1 - 7.2e-36 122.7 0.0 1.2e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EGD84304.1 - 6.1e-21 74.1 0.0 2.7e-20 72.1 0.0 2.0 2 0 0 2 2 2 1 Vps23 core domain ADIP PF11559.8 EGD84304.1 - 0.032 14.3 2.2 0.05 13.7 2.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Paralemmin PF03285.15 EGD84304.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Paralemmin Snapin_Pallidin PF14712.6 EGD84304.1 - 0.15 12.5 0.7 0.26 11.8 0.7 1.3 1 0 0 1 1 1 0 Snapin/Pallidin AAA_13 PF13166.6 EGD84304.1 - 0.19 10.4 0.1 0.24 10.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EGD84305.1 - 1.3e-13 51.2 8.2 0.011 16.6 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD84305.1 - 2.1e-08 34.3 0.2 0.091 13.1 0.0 4.5 2 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGD84305.1 - 0.019 13.9 0.4 2.3 7.1 0.0 3.0 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein STE2 PF02116.15 EGD84306.1 - 6.6e-94 314.3 29.6 7.9e-94 314.1 29.6 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Metallophos PF00149.28 EGD84307.1 - 7.2e-08 33.2 0.2 1.1e-07 32.6 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kdo PF06293.14 EGD84310.2 - 5.9e-09 35.6 0.0 0.005 16.2 0.0 3.1 3 0 0 3 3 3 3 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGD84310.2 - 1.3e-07 31.8 0.0 0.0086 16.0 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.25 EGD84310.2 - 1.7e-06 27.6 0.0 2.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGD84310.2 - 0.0093 14.8 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EGD84310.2 - 0.018 14.3 0.0 0.04 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase RIO1 PF01163.22 EGD84310.2 - 0.026 14.1 0.0 1.3 8.5 0.0 2.8 3 0 0 3 3 3 0 RIO1 family Aldo_ket_red PF00248.21 EGD84311.1 - 7.5e-14 51.6 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 EGD84312.1 - 8.1e-53 178.2 1.9 9.7e-53 177.9 1.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 EGD84312.1 - 0.056 14.2 0.2 0.1 13.3 0.2 1.5 1 1 0 1 1 1 0 Pullulanase N1-terminal domain Maf1 PF09174.10 EGD84313.1 - 5.1e-64 215.6 0.0 7e-64 215.2 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Filament PF00038.21 EGD84314.2 - 0.0079 15.8 17.5 0.0079 15.8 17.5 2.6 1 1 1 2 2 2 2 Intermediate filament protein Ribosomal_L12 PF00542.19 EGD84314.2 - 0.024 15.0 1.8 0.024 15.0 1.8 2.7 2 1 1 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain ATG16 PF08614.11 EGD84314.2 - 0.035 14.3 39.2 0.59 10.3 17.6 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) HemX PF04375.14 EGD84314.2 - 0.035 13.4 21.8 0.016 14.5 13.8 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase ATP-cone PF03477.16 EGD84314.2 - 0.066 13.8 2.2 0.18 12.4 2.2 1.8 1 0 0 1 1 1 0 ATP cone domain DUF3584 PF12128.8 EGD84314.2 - 2.8 5.3 30.6 4.3 4.7 30.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RIC3 PF15361.6 EGD84314.2 - 5 7.5 23.7 1.4 9.3 5.0 3.7 1 1 2 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 DUF87 PF01935.17 EGD84314.2 - 6.7 6.7 10.2 5.2 7.1 8.3 1.8 1 1 1 2 2 2 0 Helicase HerA, central domain N2227 PF07942.12 EGD84315.1 - 5.3e-61 206.2 0.0 7e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EGD84315.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SpoU_sub_bind PF08032.12 EGD84315.1 - 0.19 12.0 0.0 0.51 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Abhydrolase_6 PF12697.7 EGD84317.1 - 3.2e-17 63.9 0.0 4.3e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGD84317.1 - 0.00025 20.4 0.1 0.0025 17.1 0.1 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EGD84317.1 - 0.0066 15.5 0.0 0.088 11.8 0.0 2.0 1 1 1 2 2 2 1 Chlorophyllase COPIIcoated_ERV PF07970.12 EGD84318.1 - 5.5e-31 108.1 0.0 1.1e-30 107.1 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGD84318.1 - 3.3e-23 81.8 0.0 5.9e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 EGD84319.2 - 1.3e-52 178.8 0.0 1.8e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84319.2 - 7e-19 68.1 0.0 1.1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 EGD84319.2 - 0.18 12.0 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 ABC1 family RIO1 PF01163.22 EGD84319.2 - 0.2 11.2 0.1 0.46 10.0 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Pex24p PF06398.11 EGD84320.2 - 6.9e-45 153.6 3.4 9.2e-39 133.5 1.1 2.1 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 EGD84320.2 - 0.0018 16.8 0.2 0.0018 16.8 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3292) ATP-synt_8 PF00895.20 EGD84320.2 - 0.61 10.6 0.0 0.61 10.6 0.0 2.2 3 0 0 3 3 3 0 ATP synthase protein 8 Nop16 PF09420.10 EGD84322.1 - 3.8e-69 232.9 13.0 4.4e-69 232.7 13.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF2121 PF09894.9 EGD84322.1 - 0.015 14.9 0.7 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) Zip PF02535.22 EGD84323.2 - 3.2e-57 194.3 10.7 2.1e-56 191.6 10.7 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Anp1 PF03452.14 EGD84324.1 - 4.4e-103 344.3 0.0 5.5e-103 344.0 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EGD84324.1 - 0.0014 18.4 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Mito_carr PF00153.27 EGD84325.1 - 5e-52 173.8 0.3 2.7e-18 65.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.7 EGD84327.2 - 1.8e-36 124.6 0.1 4e-08 33.7 0.0 4.2 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EGD84327.2 - 7.6e-28 95.7 9.0 0.00015 22.0 0.1 8.4 8 1 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 EGD84327.2 - 1.5e-26 92.1 4.7 4e-07 30.2 0.6 5.3 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD84327.2 - 7.9e-26 87.3 0.8 9.5e-06 25.6 0.1 8.1 7 1 1 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 EGD84327.2 - 8e-25 86.9 1.9 0.00016 22.2 0.0 6.6 2 2 6 8 8 8 7 Ankyrin repeats (many copies) p450 PF00067.22 EGD84328.1 - 2.9e-07 29.6 0.0 5.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Chorismate_bind PF00425.18 EGD84329.2 - 6e-43 147.3 0.0 8e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme DHDPS PF00701.22 EGD84332.1 - 5.5e-40 136.9 0.0 6.4e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2014 PF09427.10 EGD84333.1 - 1.3e-102 342.7 0.1 1.8e-102 342.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 EGD84333.1 - 6.3e-18 64.5 1.8 1.3e-17 63.5 1.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 EGD84333.1 - 0.11 13.0 1.1 0.17 12.3 0.3 1.7 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 EGD84333.1 - 0.57 10.3 3.5 0.54 10.4 2.0 1.7 2 0 0 2 2 2 0 bZIP transcription factor E1-E2_ATPase PF00122.20 EGD84334.1 - 1.2e-39 135.7 15.9 1.7e-31 109.2 0.0 3.8 3 1 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGD84334.1 - 5.7e-27 94.6 2.8 5.7e-27 94.6 2.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGD84334.1 - 1.4e-17 64.7 0.3 3.8e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGD84334.1 - 7.8e-16 57.5 0.1 8.2e-15 54.3 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGD84334.1 - 9.5e-13 48.0 0.0 1.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGD84334.1 - 1.9e-05 24.6 1.5 1.9e-05 24.6 1.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 EGD84334.1 - 0.0024 17.8 1.3 0.0068 16.3 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) RNase_PH PF01138.21 EGD84336.1 - 0.13 12.7 0.1 0.27 11.8 0.1 1.5 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 Peptidase_S15 PF02129.18 EGD84336.1 - 0.2 11.2 0.3 0.93 9.0 0.1 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Pro-kuma_activ PF09286.11 EGD84337.1 - 1.2e-34 119.6 0.0 2e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGD84337.1 - 1.1e-07 31.5 0.1 2.4e-07 30.3 0.1 1.5 1 1 0 1 1 1 1 Subtilase family NAD_kinase PF01513.21 EGD84338.1 - 4.8e-80 268.9 0.0 7.2e-80 268.3 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAO PF01266.24 EGD84339.1 - 4.2e-43 148.3 0.0 4.9e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGD84339.1 - 0.011 15.0 0.0 0.66 9.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGD84339.1 - 0.028 13.6 0.0 0.27 10.3 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EGD84339.1 - 0.033 13.4 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GAF_2 PF13185.6 EGD84340.2 - 1.2e-11 45.0 0.0 1.5e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EGD84340.2 - 8.2e-06 26.5 0.0 1e-05 26.1 0.0 1.2 1 0 0 1 1 1 1 GAF domain DEAD PF00270.29 EGD84341.1 - 1.4e-35 122.7 0.6 5.5e-35 120.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD84341.1 - 6.9e-24 84.3 0.1 2.3e-23 82.6 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EGD84341.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.25 EGD84341.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) C1_1 PF00130.22 EGD84342.2 - 4.3e-16 58.5 5.2 6.3e-16 58.0 5.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EGD84342.2 - 0.013 15.8 4.7 0.022 15.1 4.7 1.3 1 0 0 1 1 1 0 C1 domain FYVE PF01363.21 EGD84342.2 - 0.088 13.0 3.0 0.17 12.1 3.0 1.4 1 0 0 1 1 1 0 FYVE zinc finger SH3_1 PF00018.28 EGD84342.2 - 0.12 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 SH3 domain OrfB_Zn_ribbon PF07282.11 EGD84342.2 - 0.43 10.6 2.9 1.2 9.1 2.9 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_9 PF13901.6 EGD84342.2 - 5 7.1 11.2 2.1e+02 1.7 11.2 2.1 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon Glyco_hydro_72 PF03198.14 EGD84343.1 - 2e-136 454.4 2.8 2.4e-136 454.1 2.8 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EGD84343.1 - 1.1e-06 28.3 0.2 6.6e-06 25.7 0.2 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Arf PF00025.21 EGD84344.2 - 5.2e-73 244.2 0.0 6.4e-73 243.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGD84344.2 - 6.4e-14 52.2 0.0 8.6e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGD84344.2 - 1.9e-11 43.7 0.0 2.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGD84344.2 - 2.8e-10 39.9 0.3 3.6e-06 26.4 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGD84344.2 - 1.3e-09 37.9 0.0 1.7e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGD84344.2 - 3.1e-08 33.3 0.0 4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGD84344.2 - 2.5e-06 27.5 0.0 4.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGD84344.2 - 0.0024 17.4 0.0 0.2 11.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGD84344.2 - 0.0073 15.9 0.5 0.03 13.8 0.5 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 EGD84344.2 - 0.14 12.7 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Paf1 PF03985.13 EGD84346.1 - 7.4e-57 193.2 0.0 1.1e-56 192.7 0.0 1.2 1 0 0 1 1 1 1 Paf1 LON_substr_bdg PF02190.16 EGD84347.2 - 2.2e-21 76.7 0.0 6e-21 75.3 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EGD84347.2 - 4.2e-11 42.5 8.6 4.2e-11 42.5 8.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD84347.2 - 5e-10 39.2 27.8 1.3e-08 34.7 2.7 3.6 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 EGD84347.2 - 2.3e-08 34.2 7.7 2.3e-08 34.2 7.7 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 EGD84347.2 - 3.2e-08 33.6 27.1 3.5e-05 23.8 9.1 3.2 3 1 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EGD84347.2 - 6.5e-08 32.3 19.9 2.7e-07 30.3 7.0 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGD84347.2 - 1.2e-07 31.5 23.1 1e-06 28.6 7.2 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 EGD84347.2 - 3.1e-07 30.2 21.0 9.6e-07 28.6 8.2 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGD84347.2 - 8.1e-05 22.7 7.0 8.1e-05 22.7 7.0 2.5 2 0 0 2 2 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 EGD84347.2 - 0.00018 21.3 6.7 0.00018 21.3 6.7 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-P11 PF03854.14 EGD84347.2 - 0.00084 19.0 6.9 0.00084 19.0 6.9 2.4 3 0 0 3 3 3 1 P-11 zinc finger zf-rbx1 PF12678.7 EGD84347.2 - 0.0021 18.3 2.8 0.0021 18.3 2.8 2.3 2 0 0 2 2 1 1 RING-H2 zinc finger domain U-box PF04564.15 EGD84347.2 - 0.013 15.7 0.1 0.04 14.1 0.1 1.8 1 0 0 1 1 1 0 U-box domain DUF1272 PF06906.11 EGD84347.2 - 9.1 6.5 14.5 0.21 11.7 5.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Uricase PF01014.18 EGD84349.1 - 1.1e-73 245.7 0.8 8.4e-40 136.1 0.8 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 EGD84349.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.18 EGD84350.1 - 2.7e-42 144.0 0.0 3.3e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 PDZ_6 PF17820.1 EGD84350.1 - 0.059 13.2 0.0 0.28 11.0 0.1 2.0 2 0 0 2 2 2 0 PDZ domain Ribosomal_S9 PF00380.19 EGD84351.1 - 1.8e-31 109.2 0.2 2e-31 109.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AAR2 PF05282.11 EGD84352.1 - 5.1e-94 315.6 0.0 5.9e-94 315.4 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S11 PF00411.19 EGD84353.2 - 3.8e-46 156.0 1.1 4.9e-46 155.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PDH PF02153.17 EGD84354.2 - 0.00016 20.8 0.0 0.00025 20.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase CDH-cyt PF16010.5 EGD84356.2 - 1.6e-26 93.1 0.1 2.6e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EGD84356.2 - 7.8e-09 35.8 12.5 7.8e-09 35.8 12.5 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 UAA PF08449.11 EGD84356.2 - 0.01 15.0 1.2 0.017 14.3 1.2 1.5 1 0 0 1 1 1 0 UAA transporter family DUF2427 PF10348.9 EGD84356.2 - 0.085 12.7 8.9 0.023 14.5 4.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) DOMON PF03351.17 EGD84356.2 - 0.097 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 DOMON domain RRM_occluded PF16842.5 EGD84357.1 - 0.0022 17.8 0.2 0.0047 16.8 0.0 1.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif Paf67 PF10255.9 EGD84358.1 - 4.7e-159 529.7 0.0 5.5e-159 529.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EGD84358.1 - 0.026 14.6 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.7 EGD84358.1 - 0.081 11.9 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Fe-S_biosyn PF01521.20 EGD84359.1 - 5.1e-10 39.5 0.0 1.8e-08 34.5 0.0 2.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Hemerythrin PF01814.23 EGD84360.1 - 7.3e-12 46.0 0.5 1.2e-11 45.3 0.5 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain UvrD_C PF13361.6 EGD84360.1 - 0.044 13.2 0.2 0.05 13.0 0.2 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Aminotran_5 PF00266.19 EGD84362.2 - 1.1e-06 27.9 0.0 1.3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGD84362.2 - 0.0009 18.6 0.1 0.0013 18.2 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EGD84362.2 - 0.028 13.0 0.0 0.085 11.4 0.0 1.6 1 1 1 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF1788 PF08747.11 EGD84362.2 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) DUF1077 PF06417.12 EGD84363.1 - 6.9e-50 168.0 3.3 8.7e-50 167.7 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TMEM171 PF15471.6 EGD84363.1 - 0.22 10.5 6.6 0.39 9.7 6.6 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF2583 PF10762.9 EGD84366.2 - 0.075 13.5 0.3 0.098 13.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) RPAP2_Rtr1 PF04181.13 EGD84369.1 - 3.9e-24 84.8 0.1 6.1e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.18 EGD84370.2 - 1.3e-58 196.2 0.4 1.8e-58 195.8 0.4 1.2 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.8 EGD84371.1 - 8e-117 390.9 0.1 9.1e-117 390.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit FAT PF02259.23 EGD84372.2 - 8.4e-132 439.6 1.9 9.2e-132 439.4 0.1 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EGD84372.2 - 3.6e-66 223.5 0.2 7e-66 222.6 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 EGD84372.2 - 3.5e-41 139.6 2.4 4.2e-40 136.2 0.1 3.8 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 EGD84372.2 - 2.8e-35 121.6 2.5 4e-32 111.3 0.5 3.4 2 1 0 2 2 2 2 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 EGD84372.2 - 0.00015 22.1 0.5 0.24 11.8 0.1 4.0 3 1 0 3 3 2 1 HEAT repeats Tti2 PF10521.9 EGD84372.2 - 0.0064 16.1 0.3 3.4 7.1 0.0 3.4 1 1 3 4 4 4 1 Tti2 family UME PF08064.13 EGD84372.2 - 0.0068 16.3 5.6 5.5 7.0 0.3 4.6 3 1 0 3 3 3 2 UME (NUC010) domain Adaptin_N PF01602.20 EGD84372.2 - 0.0072 14.9 1.8 0.0092 14.6 0.1 2.0 3 0 0 3 3 3 1 Adaptin N terminal region TPR_19 PF14559.6 EGD84372.2 - 0.032 14.7 1.0 8.6 7.0 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat HEAT PF02985.22 EGD84372.2 - 0.1 12.9 0.1 13 6.4 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 EGD84372.2 - 0.12 13.0 2.1 11 6.6 0.0 5.0 5 0 0 5 5 5 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGD84372.2 - 0.14 12.8 1.8 3.4 8.3 0.0 3.7 3 1 1 4 4 3 0 Vacuolar 14 Fab1-binding region TPR_14 PF13428.6 EGD84372.2 - 0.26 12.2 11.0 16 6.6 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGD84372.2 - 0.27 11.0 6.0 1.4 8.7 0.0 4.0 4 0 0 4 4 4 0 TPR repeat Rnf-Nqr PF02508.14 EGD84372.2 - 0.5 10.3 1.6 1 9.4 1.6 1.5 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein Pam16 PF03656.13 EGD84375.2 - 2.5e-35 121.3 0.2 3.2e-35 120.9 0.2 1.2 1 0 0 1 1 1 1 Pam16 MatC_N PF07158.11 EGD84375.2 - 0.18 11.8 0.1 0.27 11.3 0.1 1.2 1 0 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus Pex24p PF06398.11 EGD84376.1 - 2.9e-97 326.0 0.9 3.5e-97 325.7 0.9 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DAHP_synth_1 PF00793.20 EGD84379.1 - 8.1e-102 339.8 0.0 9.4e-102 339.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2458 PF10454.9 EGD84380.1 - 5.1e-66 221.6 1.1 6.9e-66 221.1 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Rtf2 PF04641.12 EGD84383.2 - 7.2e-55 186.2 0.2 9.5e-55 185.8 0.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 EGD84383.2 - 1.5e-09 37.5 0.0 0.00046 19.9 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGD84383.2 - 0.00037 20.5 1.0 0.0025 17.8 0.0 2.8 3 1 1 4 4 4 1 RING-type zinc-finger zf-NOSIP PF15906.5 EGD84383.2 - 0.0022 18.1 0.0 0.0045 17.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 EGD84383.2 - 0.006 16.5 0.2 0.015 15.2 0.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGD84383.2 - 0.024 14.5 0.1 0.068 13.0 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGD84383.2 - 0.04 13.8 0.7 0.53 10.2 0.3 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGD84383.2 - 0.096 13.0 0.8 0.22 11.9 0.2 2.0 2 0 0 2 2 2 0 Ring finger domain PRKCSH_1 PF13015.6 EGD84384.2 - 9.8e-31 106.5 0.4 9.8e-31 106.5 0.4 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.7 EGD84384.2 - 3.1e-20 72.7 5.0 3.2e-20 72.7 2.5 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH PF07915.13 EGD84384.2 - 1.7e-09 38.5 0.5 1.7e-09 38.5 0.5 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Arteri_nucleo PF01481.16 EGD84384.2 - 0.028 14.7 0.2 1 9.7 0.0 2.5 2 1 0 2 2 2 0 Arterivirus nucleocapsid protein Herpes_UL6 PF01763.16 EGD84384.2 - 0.052 12.1 2.4 0.077 11.5 2.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4407 PF14362.6 EGD84384.2 - 0.078 12.3 11.6 0.14 11.5 11.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1985 PF09331.11 EGD84384.2 - 0.094 12.7 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) HMG_box PF00505.19 EGD84384.2 - 0.097 13.1 2.6 0.24 11.8 2.6 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box DUF3450 PF11932.8 EGD84384.2 - 0.097 12.0 14.7 0.22 10.8 12.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) NBP1 PF08537.10 EGD84384.2 - 0.14 11.6 4.5 0.34 10.3 4.5 1.6 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 CorA PF01544.18 EGD84384.2 - 0.14 11.5 4.8 0.26 10.6 4.8 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ax_dynein_light PF10211.9 EGD84384.2 - 0.38 10.7 16.5 0.022 14.7 11.1 1.8 2 0 0 2 2 2 0 Axonemal dynein light chain ATG27 PF09451.10 EGD84384.2 - 0.77 9.6 9.0 0.019 14.8 2.3 1.6 2 0 0 2 2 2 0 Autophagy-related protein 27 Laminin_II PF06009.12 EGD84384.2 - 1.2 9.1 10.9 1.8 8.6 2.5 2.6 3 0 0 3 3 3 0 Laminin Domain II Nsp1_C PF05064.13 EGD84384.2 - 1.8 8.4 7.9 0.6 9.9 3.2 2.4 1 1 1 2 2 2 0 Nsp1-like C-terminal region TMPIT PF07851.13 EGD84384.2 - 6.2 6.0 6.8 11 5.1 6.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein Fmp27_WPPW PF10359.9 EGD84384.2 - 6.2 5.5 8.1 1.8 7.3 4.8 1.7 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain NTP_transf_2 PF01909.23 EGD84388.2 - 6.1e-12 45.7 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EGD84388.2 - 4.9e-07 29.9 0.0 1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 EGD84388.2 - 0.0081 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Aldo_ket_red PF00248.21 EGD84389.1 - 2.5e-66 223.9 0.0 3.1e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FA_hydroxylase PF04116.13 EGD84390.1 - 5e-25 88.4 25.6 2e-24 86.4 22.6 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily COX14 PF14880.6 EGD84391.1 - 8.2e-19 67.2 0.5 2.7e-18 65.6 0.0 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly HetR_C PF18460.1 EGD84391.1 - 0.057 13.3 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain CENP-Q PF13094.6 EGD84391.1 - 0.26 11.5 4.4 0.42 10.8 3.7 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF572 PF04502.13 EGD84391.1 - 0.39 10.3 4.2 0.085 12.5 0.9 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) Methyltransf_23 PF13489.6 EGD84392.2 - 2.1e-19 70.0 0.0 3.8e-19 69.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD84392.2 - 8.7e-09 36.0 0.0 4e-08 33.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD84392.2 - 2e-07 31.6 0.0 5e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD84392.2 - 0.00025 21.7 0.0 0.00087 20.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD84392.2 - 0.00081 19.2 0.0 0.0077 16.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD84392.2 - 0.0057 16.0 0.0 0.017 14.4 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family HP_OMP_2 PF02521.14 EGD84392.2 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative outer membrane protein PCMT PF01135.19 EGD84392.2 - 0.15 11.7 0.0 0.72 9.6 0.0 1.9 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.15 EGD84392.2 - 0.16 11.3 0.0 12 5.2 0.0 2.1 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Peptidase_M35 PF02102.15 EGD84394.1 - 9.2e-99 330.7 0.7 1.1e-98 330.4 0.7 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EGD84394.1 - 3.4e-41 141.2 3.2 6.4e-41 140.3 3.2 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Glyco_hydro_32N PF00251.20 EGD84394.1 - 0.014 15.0 0.1 0.02 14.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Actin PF00022.19 EGD84395.1 - 3.2e-141 470.7 0.0 3.6e-141 470.5 0.0 1.0 1 0 0 1 1 1 1 Actin ATG22 PF11700.8 EGD84396.1 - 1.1e-198 660.8 15.3 1.2e-198 660.6 15.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EGD84396.1 - 6e-07 28.7 48.8 0.0014 17.6 26.2 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 EGD84396.1 - 0.0027 16.3 6.2 0.0027 16.3 6.2 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein Mpp10 PF04006.12 EGD84397.1 - 3.6e-111 372.6 63.9 3.3e-110 369.4 63.9 1.9 1 1 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.9 EGD84398.1 - 3.1e-46 157.3 0.0 4.1e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EGD84398.1 - 0.0017 18.0 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGD84398.1 - 0.0035 16.8 0.1 0.0056 16.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 EGD84398.1 - 0.02 14.5 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CI-B14_5a PF07347.12 EGD84399.1 - 0.082 12.8 0.2 0.22 11.4 0.0 1.8 2 1 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) AhpC-TSA PF00578.21 EGD84400.1 - 9.4e-23 80.5 0.0 1.4e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGD84400.1 - 4.2e-13 49.2 0.0 6.5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EGD84400.1 - 0.0079 16.3 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Pox_Ag35 PF03286.14 EGD84400.1 - 0.28 11.0 14.8 0.42 10.4 14.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NPR3 PF03666.13 EGD84400.1 - 0.79 8.4 5.6 0.92 8.2 5.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Spore_coat_CotO PF14153.6 EGD84400.1 - 1.3 8.9 14.0 38 4.1 16.0 2.0 2 0 0 2 2 2 0 Spore coat protein CotO NARP1 PF12569.8 EGD84400.1 - 6.5 5.5 13.1 8.5 5.2 13.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 EGD84400.1 - 6.8 6.4 13.9 8.9 6.0 13.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CH PF00307.31 EGD84401.1 - 2.2e-75 249.8 0.0 4.7e-20 71.8 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EGD84401.1 - 1.3e-07 32.0 1.5 2.1e-06 28.1 0.6 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGD84401.1 - 9.1e-05 22.1 0.9 0.012 15.4 0.1 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGD84401.1 - 0.00021 20.6 2.2 0.63 9.7 0.1 3.7 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.8 EGD84401.1 - 0.00038 20.2 0.0 0.6 10.0 0.0 3.9 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_5 PF13202.6 EGD84401.1 - 0.43 10.2 1.8 3.7 7.2 0.1 2.8 2 0 0 2 2 2 0 EF hand Hydantoinase_B PF02538.14 EGD84402.1 - 4e-221 734.9 0.0 5.6e-221 734.4 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EGD84402.1 - 2.2e-102 342.3 0.5 2.2e-102 342.3 0.5 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGD84402.1 - 1.5e-59 200.7 1.0 4.2e-58 196.0 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region PC4 PF02229.16 EGD84403.1 - 6.9e-24 83.2 0.1 1e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) MIT PF04212.18 EGD84404.2 - 3.2e-14 52.7 0.8 7.1e-14 51.6 0.8 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain BTB PF00651.31 EGD84406.1 - 0.0056 16.9 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_M24 PF00557.24 EGD84407.1 - 6.4e-57 192.6 0.0 8.4e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGD84407.1 - 1.8e-23 82.6 0.0 3.5e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TIP41 PF04176.13 EGD84409.2 - 1.5e-68 229.7 0.0 2e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.25 EGD84410.1 - 5.1e-70 235.9 0.0 6.2e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84410.1 - 1.5e-42 145.7 0.0 1.9e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD84410.1 - 2.8e-07 30.2 0.0 3.7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGD84410.1 - 0.00014 21.3 0.2 0.00022 20.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGD84410.1 - 0.0019 17.2 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGD84410.1 - 0.02 14.5 0.1 0.08 12.5 0.0 1.7 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 EGD84410.1 - 0.085 12.8 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGD84410.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EGD84410.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_M76 PF09768.9 EGD84411.2 - 8.4e-66 221.0 1.7 8.4e-66 221.0 1.7 1.6 2 0 0 2 2 2 1 Peptidase M76 family SprT-like PF10263.9 EGD84411.2 - 0.00098 19.0 0.5 0.0024 17.7 0.4 1.6 1 1 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 EGD84411.2 - 0.012 16.0 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 Effector protein CAF20 PF17052.5 EGD84411.2 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Cap associated factor Tox-MPTase2 PF15638.6 EGD84411.2 - 0.21 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 PALP PF00291.25 EGD84412.1 - 5.1e-65 219.8 0.1 6.3e-65 219.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EGD84412.1 - 1.7e-10 41.2 0.0 5.5e-07 29.9 0.0 3.1 4 0 0 4 4 4 2 CBS domain FIST PF08495.10 EGD84412.1 - 0.13 12.2 0.3 0.75 9.8 0.3 2.4 1 1 0 1 1 1 0 FIST N domain SRPRB PF09439.10 EGD84413.1 - 3.8e-26 91.6 0.2 1.4e-24 86.6 0.2 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EGD84413.1 - 1e-06 28.3 0.0 0.0013 18.2 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGD84413.1 - 0.00012 22.2 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGD84413.1 - 0.0021 18.4 0.7 0.0049 17.3 0.1 1.8 1 1 1 2 2 2 1 AAA ATPase domain SRP54 PF00448.22 EGD84413.1 - 0.0065 16.1 0.3 0.11 12.1 0.3 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 EGD84413.1 - 0.02 14.9 0.0 0.039 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGD84413.1 - 0.03 14.6 0.2 0.067 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGD84413.1 - 0.037 13.8 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EGD84413.1 - 0.038 13.8 0.0 8.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 EGD84413.1 - 0.04 13.3 0.0 0.072 12.4 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Roc PF08477.13 EGD84413.1 - 0.042 14.1 0.0 0.39 10.9 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EGD84413.1 - 0.043 13.7 0.1 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EGD84413.1 - 0.052 13.3 0.5 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 EGD84413.1 - 0.094 12.6 0.0 0.67 9.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 EGD84413.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Se-cys_synth_N PF12390.8 EGD84413.1 - 0.14 12.4 0.9 2.9 8.2 0.1 2.4 2 0 0 2 2 2 0 Selenocysteine synthase N terminal ABC_tran PF00005.27 EGD84413.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF2855 PF11017.8 EGD84413.1 - 0.18 11.6 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) PEPCK_ATP PF01293.20 EGD84413.1 - 0.21 10.2 0.1 0.32 9.6 0.1 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase GPI-anchored PF10342.9 EGD84414.1 - 5.4e-10 39.9 0.1 1.2e-09 38.8 0.0 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.11 EGD84414.1 - 2.9e-08 34.4 3.2 5.6e-08 33.5 3.2 1.4 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 AA_kinase PF00696.28 EGD84415.2 - 2.4e-42 145.2 0.8 3.5e-42 144.6 0.8 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EGD84415.2 - 7.3e-12 45.1 0.0 6.9e-11 42.0 0.0 2.4 2 0 0 2 2 2 1 PUA domain Pkinase PF00069.25 EGD84417.1 - 2e-41 142.1 0.0 3e-40 138.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84417.1 - 3.6e-23 82.2 0.0 5.6e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGD84417.1 - 0.039 13.9 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AMP-binding PF00501.28 EGD84419.2 - 1.1e-221 735.8 0.0 1.2e-77 261.3 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EGD84419.2 - 1e-187 624.4 0.0 1.3e-42 146.1 0.0 6.8 6 2 0 6 6 6 6 Condensation domain PP-binding PF00550.25 EGD84419.2 - 1.1e-55 185.9 16.5 2e-09 37.7 0.1 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGD84419.2 - 9.6e-15 55.3 0.0 5.1e-06 27.4 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 EGD84419.2 - 0.12 12.2 0.8 43 3.8 0.0 3.7 4 0 0 4 4 4 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF722 PF05263.11 EGD84419.2 - 0.12 12.5 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF722) K_oxygenase PF13434.6 EGD84420.2 - 3.1e-82 276.5 0.0 3.6e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGD84420.2 - 0.00042 20.3 0.0 0.0015 18.5 0.0 1.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGD84420.2 - 0.00074 18.8 0.0 0.0015 17.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase OB_NTP_bind PF07717.16 EGD84422.1 - 2.2e-21 76.0 0.0 5.8e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EGD84422.1 - 2.4e-19 69.6 0.0 2.4e-19 69.6 0.0 3.8 4 1 0 4 4 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGD84422.1 - 5.4e-13 49.3 0.0 1.2e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGD84422.1 - 7.4e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PWI PF01480.17 EGD84422.1 - 9.6e-06 25.8 0.0 2.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 PWI domain AAA_22 PF13401.6 EGD84422.1 - 1.4e-05 25.4 0.1 0.00012 22.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGD84422.1 - 0.00038 20.2 0.1 0.00089 19.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGD84422.1 - 0.0025 16.9 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EGD84422.1 - 0.0026 18.1 0.1 0.0054 17.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EGD84422.1 - 0.016 14.9 0.2 0.039 13.6 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.6 EGD84422.1 - 0.038 14.1 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 EGD84422.1 - 0.099 13.1 0.0 0.099 13.1 0.0 4.0 1 1 1 2 2 1 0 AAA domain AAA_16 PF13191.6 EGD84422.1 - 0.14 12.5 1.2 0.25 11.7 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain AAA_7 PF12775.7 EGD84422.1 - 0.16 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EGD84422.1 - 1.6 9.3 5.0 0.52 10.8 0.2 2.7 2 1 1 3 3 2 0 ABC transporter Cyt-b5 PF00173.28 EGD84423.2 - 2.9e-20 72.2 0.1 3.5e-20 71.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4430 PF14478.6 EGD84423.2 - 0.073 13.7 0.1 0.14 12.7 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4430) DUF4291 PF14124.6 EGD84424.1 - 1.2e-71 240.4 0.1 1.3e-71 240.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) DUF3378 PF11858.8 EGD84424.1 - 0.19 11.9 0.2 0.35 11.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) Mcp5_PH PF12814.7 EGD84425.1 - 4.7e-46 155.9 0.9 5.9e-46 155.5 0.0 1.7 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 EGD84425.1 - 0.00057 20.4 10.1 0.0012 19.3 10.1 1.5 1 0 0 1 1 1 1 Fez1 DUF3584 PF12128.8 EGD84425.1 - 0.092 10.3 11.3 0.13 9.8 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 EGD84425.1 - 0.32 11.1 17.3 1.7 8.7 9.5 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 EGD84425.1 - 0.4 10.5 2.4 0.72 9.7 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Lebercilin PF15619.6 EGD84425.1 - 1.2 8.8 12.0 2 8.0 12.0 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease AMP-binding PF00501.28 EGD84426.2 - 1.5e-31 109.4 0.0 1.9e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD84426.2 - 2e-14 54.3 0.0 5.2e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ras PF00071.22 EGD84427.1 - 3.4e-50 169.8 0.5 7.2e-49 165.5 0.5 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGD84427.1 - 3.8e-18 65.8 0.1 8.8e-17 61.4 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD84427.1 - 0.0002 20.9 0.0 0.0017 17.9 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family SUIM_assoc PF16619.5 EGD84427.1 - 0.018 15.1 1.4 0.039 14.0 1.4 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 AAA_16 PF13191.6 EGD84427.1 - 0.086 13.2 0.2 0.19 12.1 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGD84427.1 - 0.11 12.4 0.0 9.6 6.1 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 EGD84427.1 - 0.11 12.0 0.1 2 7.9 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B Septin PF00735.18 EGD84427.1 - 0.12 11.6 0.6 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 EGD84427.1 - 0.14 11.7 0.1 0.34 10.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.16 EGD84428.1 - 2.9e-36 125.1 33.1 2.9e-36 125.1 33.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily SH PF01445.17 EGD84428.1 - 0.016 15.2 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 Viral small hydrophobic protein Trp_oprn_chp PF09534.10 EGD84428.1 - 1.4 8.7 6.0 5.4 6.8 0.1 2.6 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SHMT PF00464.19 EGD84430.1 - 1.1e-195 649.8 0.0 1.3e-195 649.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Mor PF08765.11 EGD84430.1 - 0.059 13.4 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Mor transcription activator family MOSC PF03473.17 EGD84431.1 - 3.5e-33 114.4 0.0 5e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EGD84431.1 - 6.1e-13 48.7 0.0 1.5e-12 47.5 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Pertus-S5-tox PF09276.10 EGD84431.1 - 0.055 13.5 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Pertussis toxin S5 subunit DUF2235 PF09994.9 EGD84432.2 - 2.5e-70 237.1 0.0 3.3e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Patatin PF01734.22 EGD84433.1 - 4.3e-15 56.4 0.0 1.2e-14 55.0 0.0 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase Mg_trans_NIPA PF05653.14 EGD84434.2 - 1.7e-07 30.7 4.4 2.2e-07 30.3 4.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA DUF5362 PF17319.2 EGD84434.2 - 0.088 12.7 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5362) PTCB-BRCT PF12738.7 EGD84435.2 - 8.4e-06 25.7 0.3 3.6e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 EGD84435.2 - 0.0038 17.6 0.0 0.0054 17.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGD84435.2 - 0.0044 17.4 0.0 0.0073 16.7 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain KilA-N PF04383.13 EGD84436.1 - 0.00046 20.0 0.0 0.0081 16.0 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain HEAT PF02985.22 EGD84441.2 - 2e-31 105.4 37.6 0.053 13.8 0.1 22.1 25 0 0 25 25 23 7 HEAT repeat HEAT_EZ PF13513.6 EGD84441.2 - 2e-21 76.1 43.9 2.2e-07 31.2 0.0 18.0 20 2 3 23 23 22 4 HEAT-like repeat HEAT_2 PF13646.6 EGD84441.2 - 6.2e-21 74.6 37.6 8.7e-06 26.0 0.0 12.5 7 4 9 17 17 16 9 HEAT repeats Vac14_Fab1_bd PF12755.7 EGD84441.2 - 2.9e-13 50.2 0.0 0.36 11.5 0.0 7.9 5 1 2 7 7 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGD84441.2 - 2e-12 47.5 7.9 0.0078 16.3 0.2 7.9 6 3 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 EGD84441.2 - 1.6e-09 38.1 2.2 0.1 12.7 0.0 6.4 5 1 0 5 5 5 2 Parkin co-regulated protein CLASP_N PF12348.8 EGD84441.2 - 1.9e-07 30.9 0.0 0.95 9.0 0.0 6.4 4 1 2 6 6 6 1 CLASP N terminal TIP120 PF08623.10 EGD84441.2 - 4.9e-07 29.7 0.5 0.0058 16.4 0.0 5.7 5 0 0 5 5 5 1 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.20 EGD84441.2 - 0.00011 20.9 13.6 1.5 7.2 0.0 5.9 5 2 1 6 6 6 3 Adaptin N terminal region IFRD PF05004.13 EGD84441.2 - 0.00028 20.1 11.3 0.39 9.8 0.1 5.4 4 0 0 4 4 4 2 Interferon-related developmental regulator (IFRD) MMS19_N PF14500.6 EGD84441.2 - 0.0044 16.6 6.8 0.96 9.0 0.0 5.6 6 2 0 6 6 6 1 Dos2-interacting transcription regulator of RNA-Pol-II RasGEF_N_2 PF14663.6 EGD84441.2 - 0.011 16.1 0.5 7.5 7.0 0.0 4.5 4 0 0 4 4 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FANCI_S2 PF14676.6 EGD84441.2 - 0.015 15.6 0.8 7.5 6.8 0.1 3.3 2 0 0 2 2 2 0 FANCI solenoid 2 Dopey_N PF04118.14 EGD84441.2 - 0.028 13.5 3.1 30 3.6 0.0 5.6 5 1 2 7 7 7 0 Dopey, N-terminal DUF937 PF06078.11 EGD84441.2 - 0.049 14.2 10.8 3.8 8.1 0.0 5.6 5 1 1 6 6 4 0 Bacterial protein of unknown function (DUF937) Pes-10 PF07149.11 EGD84441.2 - 0.066 12.3 0.7 0.16 11.0 0.7 1.6 1 0 0 1 1 1 0 Pes-10 DUF3535 PF12054.8 EGD84441.2 - 0.11 11.8 1.3 0.97 8.6 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3535) Tti2 PF10521.9 EGD84441.2 - 0.14 11.7 9.8 19 4.7 0.0 6.0 6 1 1 7 7 7 0 Tti2 family Cohesin_HEAT PF12765.7 EGD84441.2 - 0.18 12.2 6.9 41 4.6 0.0 6.3 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 EGD84441.2 - 0.25 11.5 9.4 49 4.2 0.0 6.6 8 0 0 8 8 6 0 Required for nuclear transport of RNA pol II C-terminus 1 Ribosomal_L19e PF01280.20 EGD84442.1 - 3e-62 209.0 7.0 3e-62 209.0 7.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e DUF4239 PF14023.6 EGD84442.1 - 0.12 12.1 1.4 0.2 11.3 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) TRAP-gamma PF07074.12 EGD84442.1 - 0.18 11.3 3.5 0.26 10.8 3.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Zn_clus PF00172.18 EGD84446.2 - 1.3e-09 38.0 11.0 2.3e-09 37.2 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YkuD PF03734.14 EGD84446.2 - 0.25 11.7 1.7 0.81 10.1 1.7 1.9 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain DUF1389 PF07146.11 EGD84447.1 - 0.025 13.9 0.0 0.057 12.7 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1389) adh_short PF00106.25 EGD84448.1 - 3.8e-35 121.1 0.1 5.3e-35 120.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD84448.1 - 4.4e-27 95.2 0.0 6.2e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD84448.1 - 6.3e-09 36.0 1.4 6e-07 29.5 2.1 2.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 EGD84448.1 - 2.2e-05 24.0 0.0 3.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGD84448.1 - 0.0032 16.6 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain UPF0146 PF03686.13 EGD84448.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) DUF3216 PF11505.8 EGD84448.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) LytR_C PF13399.6 EGD84448.1 - 0.17 12.9 0.1 0.72 10.9 0.0 2.0 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator CorA PF01544.18 EGD84450.2 - 1.2e-20 74.1 0.0 3e-20 72.7 0.0 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Vac7 PF12751.7 EGD84452.1 - 6.5e-137 457.0 0.6 6.5e-137 457.0 0.6 3.2 2 1 0 2 2 2 1 Vacuolar segregation subunit 7 DUF3824 PF12868.7 EGD84455.2 - 1.7e-14 54.7 24.8 1.7e-14 54.7 24.8 9.8 2 2 6 9 9 9 1 Domain of unknwon function (DUF3824) NDUF_B12 PF08122.12 EGD84455.2 - 0.0055 16.7 1.2 0.26 11.3 0.0 3.6 3 1 1 4 4 4 1 NADH-ubiquinone oxidoreductase B12 subunit family Transformer PF06495.11 EGD84455.2 - 0.0088 16.2 5.9 0.0088 16.2 5.9 6.9 3 3 2 6 6 6 1 Fruit fly transformer protein RskA PF10099.9 EGD84455.2 - 0.02 15.2 9.3 3.6 7.8 0.0 3.6 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF4473 PF14747.6 EGD84455.2 - 0.057 14.0 6.2 0.61 10.7 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) CbtA PF09490.10 EGD84455.2 - 0.22 11.3 2.6 0.29 10.9 0.0 2.5 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtA) STALD PF18185.1 EGD84455.2 - 0.49 9.7 3.4 6 6.1 0.8 2.2 1 1 0 2 2 2 0 Sir2- and TIR-associating SLOG family GNAT_acetyltr_2 PF13718.6 EGD84455.2 - 9.4 5.6 7.2 3.3 7.1 0.2 2.4 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Amidohydro_1 PF01979.20 EGD84456.1 - 1.4e-19 70.7 2.1 2e-19 70.1 2.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGD84456.1 - 1.6e-14 54.3 4.9 8.7e-13 48.5 1.1 2.1 1 1 0 2 2 2 2 Amidohydrolase family Abhydrolase_1 PF00561.20 EGD84458.1 - 3.2e-21 76.1 0.0 3.5e-15 56.4 0.1 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD84458.1 - 5e-19 69.8 0.1 6e-19 69.5 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGD84458.1 - 1.3e-18 67.2 0.0 2.7e-18 66.1 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGD84458.1 - 0.00024 21.3 0.0 0.00036 20.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 EGD84458.1 - 0.00032 19.5 0.0 0.00041 19.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.13 EGD84458.1 - 0.012 15.3 0.6 0.63 9.7 0.5 2.2 1 1 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.13 EGD84458.1 - 0.1 12.3 0.0 0.29 10.8 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF348 PF03990.14 EGD84458.1 - 0.17 11.7 1.0 26 4.7 0.0 2.9 3 0 0 3 3 3 0 G5-linked-Ubiquitin-like domain DUF915 PF06028.11 EGD84458.1 - 0.25 10.6 0.1 26 4.0 0.0 2.7 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Fungal_trans PF04082.18 EGD84459.2 - 2.4e-06 26.8 0.6 7.8e-06 25.1 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ribosomal_L44 PF00935.19 EGD84460.2 - 3.1e-35 120.5 12.1 3.1e-35 120.5 12.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L44 ubiquitin PF00240.23 EGD84461.1 - 6.8e-24 83.4 0.0 7.6e-24 83.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGD84461.1 - 4.1e-13 48.9 0.0 4.5e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGD84461.1 - 9.9e-05 22.7 0.0 0.00029 21.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGD84461.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rav1p_C PF12234.8 EGD84463.2 - 2.7e-94 316.8 0.0 8e-94 315.3 0.0 1.7 2 0 0 2 2 2 1 RAVE protein 1 C terminal OPT PF03169.15 EGD84464.1 - 4.4e-161 537.6 19.1 5e-161 537.4 19.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SH3_9 PF14604.6 EGD84465.1 - 7.6e-09 35.3 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGD84465.1 - 6.3e-06 25.7 0.0 9.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGD84465.1 - 1.9e-05 24.2 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 EGD84465.1 - 0.0011 19.1 0.2 0.0011 19.1 0.2 1.7 2 0 0 2 2 2 1 Podoplanin DUF4366 PF14283.6 EGD84465.1 - 0.72 9.9 5.7 3.6 7.6 0.0 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4366) PepSY_TM PF03929.16 EGD84465.1 - 3.9 7.1 5.5 14 5.2 0.1 2.8 3 0 0 3 3 3 0 PepSY-associated TM region Pkinase PF00069.25 EGD84466.2 - 3.3e-37 128.3 0.0 4.7e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84466.2 - 2e-13 50.2 0.0 2.8e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase KIX_2 PF16987.5 EGD84466.2 - 0.0025 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 KIX domain APH PF01636.23 EGD84466.2 - 0.0063 16.5 0.1 0.023 14.6 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGD84466.2 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EGD84466.2 - 0.014 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGD84466.2 - 0.014 14.7 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGD84466.2 - 0.033 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EGD84466.2 - 0.23 11.0 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL muHD PF10291.9 EGD84467.2 - 5.3e-74 249.0 0.0 7.5e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Laminin_II PF06009.12 EGD84467.2 - 0.034 14.2 2.6 0.11 12.6 2.6 1.9 1 0 0 1 1 1 0 Laminin Domain II Spc7 PF08317.11 EGD84467.2 - 0.16 10.8 3.3 0.28 10.0 3.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4349 PF14257.6 EGD84467.2 - 0.61 9.5 3.4 0.37 10.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) PilJ PF13675.6 EGD84467.2 - 1.2 9.2 9.0 0.18 11.9 1.8 3.1 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term OmpH PF03938.14 EGD84467.2 - 1.4 9.2 7.5 0.87 9.9 1.7 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) M20_dimer PF07687.14 EGD84468.2 - 1.9e-18 66.3 0.0 3.8e-18 65.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase dimerisation domain MAD PF05557.13 EGD84469.1 - 7.7e-60 203.0 71.7 1.9e-51 175.3 72.8 2.2 2 0 0 2 2 2 2 Mitotic checkpoint protein CC2-LZ PF16516.5 EGD84469.1 - 0.13 12.6 0.1 0.13 12.6 0.1 8.9 5 3 2 7 7 7 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Arginosuc_synth PF00764.19 EGD84470.2 - 1.2e-154 515.3 0.0 1.4e-154 515.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EGD84470.2 - 0.0024 17.4 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EGD84470.2 - 0.021 13.6 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Glyco_hydro_114 PF03537.13 EGD84470.2 - 0.05 12.9 0.1 0.085 12.2 0.1 1.3 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 DUF2624 PF11116.8 EGD84470.2 - 0.17 12.8 0.0 0.4 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) DNA_pol3_gamma3 PF12169.8 EGD84470.2 - 0.17 11.8 0.1 0.48 10.3 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III RasGEF PF00617.19 EGD84472.1 - 1.3e-41 142.8 0.2 2e-41 142.1 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGD84472.1 - 1.9e-13 50.5 0.2 4.4e-13 49.4 0.2 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif DIL PF01843.19 EGD84473.1 - 1.3e-29 102.5 1.1 1.3e-29 102.5 1.1 2.0 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 EGD84473.1 - 3.3e-13 50.0 0.2 1.4e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGD84473.1 - 4.2e-10 39.7 0.0 4.5e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGD84473.1 - 2.4e-09 37.2 0.2 0.0063 16.9 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGD84473.1 - 1e-07 32.4 0.3 0.00045 20.7 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD84473.1 - 8.2e-07 28.9 0.5 0.011 16.1 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat RabGAP-TBC PF00566.18 EGD84478.1 - 7e-36 123.9 0.0 1.1e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DPCD PF14913.6 EGD84478.1 - 0.036 13.4 0.2 0.066 12.6 0.2 1.3 1 0 0 1 1 1 0 DPCD protein family Diphthami_syn_2 PF01902.17 EGD84479.1 - 0.12 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Diphthamide synthase TPP_enzyme_N PF02776.18 EGD84480.1 - 6.4e-41 139.8 0.0 1.2e-40 138.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGD84480.1 - 1.5e-18 67.0 0.0 3.5e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGD84480.1 - 6.2e-14 51.9 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Mo25 PF08569.11 EGD84481.1 - 1e-132 442.4 0.0 1.2e-132 442.3 0.0 1.0 1 0 0 1 1 1 1 Mo25-like Methyltransf_25 PF13649.6 EGD84482.1 - 2.4e-10 41.0 0.0 6.1e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD84482.1 - 5.8e-09 35.9 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGD84482.1 - 1.6e-08 34.3 0.0 2.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGD84482.1 - 2.1e-08 34.7 0.0 4.7e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD84482.1 - 8.4e-06 25.7 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGD84482.1 - 3.5e-05 23.8 0.0 7.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGD84482.1 - 0.0001 21.9 0.1 0.00018 21.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EGD84482.1 - 0.00035 19.6 0.0 0.00051 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RasGAP_C PF03836.15 EGD84482.1 - 0.004 17.3 0.5 0.0085 16.2 0.5 1.4 1 0 0 1 1 1 1 RasGAP C-terminus Methyltransf_12 PF08242.12 EGD84482.1 - 0.011 16.5 0.0 0.025 15.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EGD84482.1 - 0.023 14.4 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 EGD84482.1 - 0.025 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.20 EGD84482.1 - 0.041 13.2 0.0 0.18 11.0 0.0 2.1 3 0 0 3 3 3 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGD84482.1 - 0.056 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EGD84482.1 - 0.063 13.3 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 EGD84482.1 - 0.063 14.3 0.0 0.17 12.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Cir_N PF10197.9 EGD84483.1 - 1.6e-06 28.2 8.4 1.6e-06 28.2 8.4 5.3 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF4733 PF15878.5 EGD84483.1 - 0.18 12.3 0.8 0.51 10.8 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4733) AAA PF00004.29 EGD84484.2 - 1.1e-53 181.2 0.0 1.4e-38 132.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD84484.2 - 9.6e-11 41.3 0.0 2.2e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGD84484.2 - 4.3e-10 40.2 0.0 0.00086 19.7 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain CDC48_2 PF02933.17 EGD84484.2 - 8e-10 38.4 0.1 2.1e-08 33.8 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 EGD84484.2 - 2.2e-09 37.7 0.0 0.00039 20.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EGD84484.2 - 2.2e-08 34.2 0.0 0.0015 18.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGD84484.2 - 3.7e-08 33.3 0.1 0.0076 16.0 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGD84484.2 - 3.7e-08 34.0 0.0 0.016 15.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.13 EGD84484.2 - 7.1e-08 32.0 0.0 0.0068 15.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EGD84484.2 - 1.4e-07 31.6 0.0 0.088 12.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EGD84484.2 - 2.2e-07 30.5 0.1 0.0046 16.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EGD84484.2 - 2.4e-07 31.0 0.0 6.6e-05 23.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EGD84484.2 - 7.8e-07 29.5 0.0 0.061 13.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 EGD84484.2 - 9.7e-07 29.0 0.0 0.03 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EGD84484.2 - 4e-06 26.7 0.0 0.013 15.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.18 EGD84484.2 - 1.4e-05 25.2 0.0 4.2e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain IstB_IS21 PF01695.17 EGD84484.2 - 1.5e-05 24.9 0.0 0.08 12.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 EGD84484.2 - 3.5e-05 23.8 1.3 0.029 14.3 0.0 3.1 3 1 0 3 3 2 1 NACHT domain TsaE PF02367.17 EGD84484.2 - 3.8e-05 23.7 0.0 0.23 11.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EGD84484.2 - 3.8e-05 23.0 0.3 0.098 11.8 0.0 2.7 3 0 0 3 3 3 2 NB-ARC domain ATPase PF06745.13 EGD84484.2 - 5.9e-05 22.5 0.4 0.019 14.3 0.2 2.6 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 EGD84484.2 - 7.1e-05 22.4 1.0 0.023 14.2 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EGD84484.2 - 0.00015 22.1 0.0 0.5 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 EGD84484.2 - 0.00028 21.3 0.1 0.16 12.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGD84484.2 - 0.00028 21.4 0.3 0.047 14.2 0.1 2.7 2 0 0 2 2 2 1 ABC transporter AAA_11 PF13086.6 EGD84484.2 - 0.00032 20.6 0.0 0.55 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGD84484.2 - 0.00033 20.3 0.3 1 8.9 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.11 EGD84484.2 - 0.00039 20.3 0.0 0.51 10.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EGD84484.2 - 0.00051 19.5 0.2 1.2 8.5 0.0 2.7 3 0 0 3 3 3 2 PhoH-like protein Sigma54_activat PF00158.26 EGD84484.2 - 0.00061 19.5 0.0 0.57 9.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 EGD84484.2 - 0.00083 19.7 0.1 0.5 10.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGD84484.2 - 0.00086 19.1 0.1 0.38 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EGD84484.2 - 0.0028 16.9 0.1 1.5 7.9 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 EGD84484.2 - 0.0036 16.4 0.0 0.42 9.7 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 EGD84484.2 - 0.0036 17.2 0.6 15 5.4 0.0 3.4 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EGD84484.2 - 0.01 15.8 0.1 7.4 6.5 0.0 3.0 3 0 0 3 3 2 0 NTPase ResIII PF04851.15 EGD84484.2 - 0.012 15.6 0.0 4.9 7.1 0.1 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 EGD84484.2 - 0.017 14.4 0.0 1.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.10 EGD84484.2 - 0.021 14.3 0.1 1.7 8.0 0.0 2.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 TniB PF05621.11 EGD84484.2 - 0.025 14.0 0.2 3.8 6.9 0.1 3.3 3 1 0 3 3 3 0 Bacterial TniB protein Vps4_C PF09336.10 EGD84484.2 - 0.047 13.7 0.0 0.21 11.6 0.0 2.2 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain SRP54 PF00448.22 EGD84484.2 - 0.064 12.9 0.2 5.4 6.6 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain IPT PF01745.16 EGD84484.2 - 0.096 12.1 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_29 PF13555.6 EGD84484.2 - 0.11 12.2 0.1 10 5.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 EGD84484.2 - 0.13 12.4 0.0 28 4.8 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain KxDL PF10241.9 EGD84487.1 - 3.5e-29 100.9 1.0 4.7e-29 100.5 1.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4407 PF14362.6 EGD84487.1 - 0.0014 18.1 1.8 0.0015 17.9 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 EGD84487.1 - 0.012 15.2 0.4 0.014 14.9 0.4 1.1 1 0 0 1 1 1 0 fzo-like conserved region Response_reg PF00072.24 EGD84488.1 - 2.7e-21 75.8 0.1 5.1e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EGD84488.1 - 2.8e-21 76.1 0.7 9.1e-21 74.5 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGD84488.1 - 7.9e-16 57.9 0.0 2.6e-15 56.2 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EGD84488.1 - 1.5e-11 44.4 1.3 0.00049 20.3 0.2 3.9 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 EGD84488.1 - 3.3e-06 27.3 0.2 1.2e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 EGD84488.1 - 0.0002 21.3 0.1 0.35 10.9 0.0 3.7 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.7 EGD84488.1 - 0.0072 16.6 0.1 3.2 8.0 0.0 3.9 4 0 0 4 4 4 1 PAS domain HATPase_c PF02518.26 EGD84490.1 - 4.7e-31 107.6 0.1 1.8e-30 105.7 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGD84490.1 - 7.9e-20 71.1 0.0 2.4e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGD84490.1 - 2.4e-19 69.1 0.0 1.4e-18 66.6 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 EGD84490.1 - 1.6e-10 41.7 0.1 1.5e-09 38.5 0.0 2.8 2 0 0 2 2 1 1 AAA ATPase domain GAF_2 PF13185.6 EGD84490.1 - 5.4e-10 39.7 0.0 2.4e-09 37.6 0.0 2.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EGD84490.1 - 7.5e-07 29.8 0.0 2.6e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 EGD84490.1 - 5.5e-06 25.9 0.0 8.5e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.6 EGD84490.1 - 1.9e-05 25.0 0.0 4.6e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 GAF domain NB-ARC PF00931.22 EGD84490.1 - 9.4e-05 21.7 0.0 0.023 13.9 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain HATPase_c_3 PF13589.6 EGD84490.1 - 0.00018 21.3 0.0 0.00048 20.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.6 EGD84490.1 - 0.01 16.1 0.0 1.3 9.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 EGD84490.1 - 0.025 13.6 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TPR_2 PF07719.17 EGD84490.1 - 0.077 13.1 2.8 6.1 7.2 0.1 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA_35 PF14516.6 EGD84490.1 - 0.093 11.5 0.0 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.6 EGD84490.1 - 0.14 12.3 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGD84490.1 - 0.15 12.0 0.0 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Cytochrom_B561 PF03188.16 EGD84492.2 - 4.3e-16 59.3 2.0 4.3e-16 59.3 2.0 1.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2306 PF10067.9 EGD84492.2 - 0.039 14.2 6.1 0.5 10.6 0.9 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) DUF4079 PF13301.6 EGD84492.2 - 0.072 13.2 8.1 2.3 8.3 8.1 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 EGD84492.2 - 0.086 12.4 7.6 1.3 8.6 7.6 2.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Bax1-I PF01027.20 EGD84492.2 - 0.42 10.4 13.2 0.66 9.8 6.5 2.2 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF1129 PF06570.11 EGD84492.2 - 0.53 9.7 4.7 1 8.8 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2427 PF10348.9 EGD84492.2 - 3 7.7 8.9 0.76 9.6 0.7 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) tRNA-synt_2b PF00587.25 EGD84493.1 - 9.8e-20 71.3 0.0 3.3e-19 69.5 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGD84493.1 - 2.6e-09 37.3 3.4 5e-09 36.4 3.4 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 EGD84493.1 - 0.00068 18.4 4.5 0.001 17.8 4.5 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Spc7 PF08317.11 EGD84493.1 - 0.017 14.0 3.0 0.027 13.4 3.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein tRNA-synt_His PF13393.6 EGD84493.1 - 0.043 13.1 1.2 1.2 8.3 1.1 2.2 2 0 0 2 2 2 0 Histidyl-tRNA synthetase TMF_TATA_bd PF12325.8 EGD84493.1 - 0.045 14.0 2.8 0.085 13.1 2.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Flagellar_rod PF05149.12 EGD84493.1 - 0.14 11.6 2.6 0.2 11.1 2.6 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein Nebulin PF00880.18 EGD84493.1 - 0.15 12.0 0.1 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 Nebulin repeat DivIC PF04977.15 EGD84493.1 - 0.17 11.7 4.1 4.7 7.0 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator Golgin_A5 PF09787.9 EGD84493.1 - 0.31 10.5 3.8 0.48 9.8 3.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 OmpH PF03938.14 EGD84493.1 - 0.51 10.7 6.7 0.88 9.9 6.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HSCB_C PF07743.13 EGD84493.1 - 1.3 9.6 6.2 5.6 7.5 1.0 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF2205 PF10224.9 EGD84493.1 - 2.4 8.2 7.2 7.5 6.6 0.2 2.4 2 0 0 2 2 2 0 Short coiled-coil protein JIP_LZII PF16471.5 EGD84493.1 - 2.4 8.4 5.6 24 5.2 0.0 2.7 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF4407 PF14362.6 EGD84493.1 - 5.5 6.3 6.8 3.1 7.1 3.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) KELK PF15796.5 EGD84493.1 - 6.6 7.3 9.0 7.8 7.0 7.5 1.8 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase APH PF01636.23 EGD84494.2 - 2.4e-05 24.4 0.0 0.0028 17.6 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.11 EGD84494.2 - 0.0022 16.9 0.0 0.005 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 EGD84494.2 - 0.04 13.1 0.0 7 5.8 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase AMP-binding PF00501.28 EGD84497.1 - 1.6e-56 191.8 0.0 2e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD84497.1 - 0.0022 18.9 0.0 0.018 16.0 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 EGD84498.1 - 1.4e-29 103.2 36.7 1.4e-29 103.2 36.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGD84498.1 - 0.1 12.3 4.9 0.26 11.0 4.6 1.9 1 1 0 1 1 1 0 Ion channel regulatory protein UNC-93 SRAP PF02586.14 EGD84503.2 - 1.2e-72 244.0 0.0 1.6e-72 243.6 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) TPR_1 PF00515.28 EGD84504.1 - 3.7e-05 23.3 5.7 0.02 14.7 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGD84504.1 - 0.00039 20.7 15.5 0.033 14.5 0.4 5.6 5 2 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGD84504.1 - 0.00087 19.2 10.5 0.13 12.4 0.3 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGD84504.1 - 0.17 12.2 15.2 0.63 10.4 0.0 5.0 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGD84504.1 - 0.24 11.9 8.7 0.21 12.1 0.4 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGD84504.1 - 1.4 9.1 12.8 5.1 7.4 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 EGD84505.1 - 2.4e-44 148.4 26.9 1.2e-09 38.7 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD84505.1 - 1.4e-09 38.1 0.6 0.06 13.7 0.0 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD84505.1 - 5.2e-05 22.1 8.5 0.1 11.3 0.1 4.7 1 1 4 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGD84505.1 - 0.0019 17.3 0.0 0.9 8.4 0.0 3.7 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGD84505.1 - 0.016 15.2 0.2 20 5.3 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EGD84505.1 - 0.02 13.4 0.0 2.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 EGD84505.1 - 0.035 13.5 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Sdh5 PF03937.16 EGD84506.1 - 2.5e-25 88.3 0.3 8.1e-25 86.6 0.2 1.8 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase EMP24_GP25L PF01105.24 EGD84507.1 - 2.8e-40 138.2 0.0 3.5e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 EGD84507.1 - 0.15 10.2 0.4 0.2 9.8 0.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA EMP24_GP25L PF01105.24 EGD84509.2 - 2.9e-40 138.2 0.0 3.5e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 EGD84509.2 - 0.15 10.2 0.4 0.2 9.8 0.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Nop14 PF04147.12 EGD84511.2 - 0.06 11.6 25.8 0.085 11.1 25.8 1.2 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 EGD84511.2 - 0.14 10.6 19.6 0.19 10.2 19.6 1.3 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 EGD84511.2 - 5.3 5.7 7.1 7.5 5.2 7.1 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PI3K_1B_p101 PF10486.9 EGD84511.2 - 6.5 4.4 6.6 8.7 4.0 6.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 EGD84511.2 - 6.5 4.9 21.2 11 4.1 21.2 1.3 1 0 0 1 1 1 0 CDC45-like protein NDUFA12 PF05071.16 EGD84514.1 - 2.8e-11 44.1 6.6 2.3e-10 41.2 6.6 2.2 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.31 EGD84515.1 - 6e-14 52.2 0.0 1.1e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 EGD84515.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin Calponin PF00402.18 EGD84515.1 - 0.17 11.5 5.5 1.1 8.9 1.3 2.7 2 0 0 2 2 2 0 Calponin family repeat CAMSAP_CH PF11971.8 EGD84515.1 - 0.19 11.6 0.0 0.43 10.4 0.0 1.6 1 1 0 1 1 1 0 CAMSAP CH domain PGA2 PF07543.12 EGD84516.2 - 0.77 9.7 6.7 1.7 8.6 5.7 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF3381 PF11861.8 EGD84516.2 - 1.2 8.9 7.1 2.4 7.9 7.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) ORMDL PF04061.14 EGD84518.2 - 5.4e-56 188.2 4.7 6.6e-56 187.9 4.7 1.1 1 0 0 1 1 1 1 ORMDL family HAD_2 PF13419.6 EGD84521.2 - 2e-15 57.4 0.0 3.7e-15 56.4 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGD84521.2 - 5.4e-13 49.7 0.0 1.2e-09 38.8 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGD84521.2 - 1.4e-06 28.3 0.0 2.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 EGD84521.2 - 0.0098 15.5 0.0 0.73 9.4 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase HAD PF12710.7 EGD84521.2 - 0.014 15.8 0.1 0.099 13.0 0.1 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase APH PF01636.23 EGD84522.1 - 2e-12 47.5 0.0 6.1e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD84522.1 - 0.0081 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EGD84522.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 EGD84522.1 - 0.016 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) APP_E2 PF12925.7 EGD84522.1 - 0.089 12.5 0.2 0.93 9.2 0.0 2.2 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein TRIQK PF15168.6 EGD84523.1 - 0.19 11.6 0.0 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family TRP PF06011.12 EGD84525.2 - 1.6e-166 554.3 28.6 1.8e-166 554.1 28.6 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGD84525.2 - 2.1e-34 118.9 0.1 3.4e-34 118.2 0.1 1.4 1 0 0 1 1 1 1 ML-like domain zf-U1 PF06220.12 EGD84526.2 - 6.6e-06 25.8 0.8 9.8e-06 25.2 0.8 1.3 1 0 0 1 1 1 1 U1 zinc finger p450 PF00067.22 EGD84527.1 - 1.1e-56 192.6 0.0 1.4e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HsbA PF12296.8 EGD84528.1 - 3e-12 47.0 0.0 3.9e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF3602 PF12223.8 EGD84529.1 - 7.3e-19 68.1 4.4 6.5e-14 52.3 0.1 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 EGD84529.1 - 0.31 10.6 4.9 16 5.0 0.3 3.1 1 1 1 3 3 3 0 GTP1/OBG Actin PF00022.19 EGD84530.2 - 8.7e-120 400.0 0.0 4.1e-119 397.8 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGD84530.2 - 0.14 11.0 0.0 6 5.6 0.0 2.6 3 0 0 3 3 3 0 MreB/Mbl protein Glyco_tran_28_C PF04101.16 EGD84531.1 - 3.4e-18 66.2 0.1 1.4e-17 64.2 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain MRP-S28 PF10213.9 EGD84532.1 - 1.4e-40 138.6 0.0 2.1e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein SpoU_methylase PF00588.19 EGD84535.1 - 4.5e-25 88.5 0.0 1e-24 87.3 0.0 1.6 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EGD84535.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding SNF2_N PF00176.23 EGD84536.2 - 1.8e-75 253.9 0.1 3.3e-75 253.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EGD84536.2 - 2.1e-43 146.9 0.9 2.1e-43 146.9 0.9 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 EGD84536.2 - 7.2e-31 107.2 4.6 7.2e-31 107.2 4.6 3.8 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 EGD84536.2 - 6.4e-18 65.1 0.6 2.8e-17 63.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD84536.2 - 8.7e-11 42.1 1.1 6e-10 39.4 0.0 3.0 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGD84536.2 - 1.4e-06 27.7 0.1 7.1e-06 25.4 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EGD84536.2 - 0.00029 20.6 0.0 0.0018 18.0 0.0 2.4 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 EGD84536.2 - 0.00056 19.7 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 EGD84536.2 - 0.0017 18.5 0.0 3.7 7.8 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF1086 PF06461.11 EGD84536.2 - 0.0034 17.2 0.1 0.0099 15.7 0.1 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) AAA_14 PF13173.6 EGD84536.2 - 0.024 14.6 0.4 0.13 12.3 0.0 2.5 2 0 0 2 2 1 0 AAA domain DEAD_2 PF06733.15 EGD84536.2 - 0.034 13.8 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 Ku_C PF03730.14 EGD84536.2 - 0.046 14.4 0.4 0.046 14.4 0.4 3.6 4 0 0 4 4 3 0 Ku70/Ku80 C-terminal arm Occludin_ELL PF07303.13 EGD84536.2 - 0.15 12.8 3.2 0.59 10.9 3.2 2.0 1 0 0 1 1 1 0 Occludin homology domain DUF4588 PF15251.6 EGD84537.1 - 8.7e-05 22.4 0.7 8.7e-05 22.4 0.7 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4588) DUF4536 PF15055.6 EGD84538.1 - 0.0026 18.0 1.3 0.0039 17.4 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) DUF1636 PF07845.11 EGD84538.1 - 0.14 12.6 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) Adap_comp_sub PF00928.21 EGD84539.2 - 2.6e-60 204.0 0.0 3.1e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Aldedh PF00171.22 EGD84540.1 - 2.9e-83 279.9 0.0 3.5e-83 279.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HC2 PF07382.11 EGD84541.2 - 1.7e-17 64.2 26.5 5.8e-13 49.4 7.9 5.9 3 2 1 5 5 5 4 Histone H1-like nucleoprotein HC2 MFS_1 PF07690.16 EGD84543.1 - 1.3e-46 159.1 40.0 2e-37 128.9 25.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD84543.1 - 2.3e-07 30.1 9.7 2.3e-07 30.1 9.7 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter TPMT PF05724.11 EGD84544.1 - 1.8e-28 99.7 0.1 1.5e-27 96.7 0.1 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 EGD84544.1 - 1.2e-06 28.4 0.1 4.3e-06 26.6 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD84544.1 - 7.7e-05 23.3 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD84544.1 - 0.00021 21.9 0.0 0.00038 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD84544.1 - 0.095 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.12 EGD84544.1 - 0.18 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein OTU PF02338.19 EGD84545.1 - 1.6e-20 73.9 0.1 4.3e-20 72.5 0.0 1.8 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGD84545.1 - 2.4e-06 27.2 0.0 0.0062 16.0 0.0 2.6 1 1 1 2 2 2 2 Peptidase C65 Otubain DUF4551 PF15087.6 EGD84545.1 - 0.61 8.8 10.7 0.76 8.5 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4407 PF14362.6 EGD84545.1 - 9.3 5.5 19.7 19 4.5 19.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) adh_short_C2 PF13561.6 EGD84546.1 - 4e-49 167.3 0.0 4.7e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD84546.1 - 1.2e-46 158.6 0.0 1.5e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD84546.1 - 1.6e-06 28.2 0.0 3.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 KR domain HTH_Tnp_IS1 PF12759.7 EGD84546.1 - 0.065 12.9 0.1 70 3.1 0.0 3.3 3 0 0 3 3 3 0 InsA C-terminal domain Trehalase PF01204.18 EGD84547.2 - 1.2e-196 654.5 0.0 1.4e-196 654.3 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EGD84547.2 - 6.1e-07 29.0 0.0 1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF4024 PF13216.6 EGD84547.2 - 0.054 13.4 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) zf-C2H2 PF00096.26 EGD84549.2 - 1.1e-06 28.7 10.1 0.00044 20.5 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD84549.2 - 0.00022 21.8 8.3 0.0051 17.6 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EGD84549.2 - 0.37 10.9 1.8 4.3 7.5 0.3 2.2 1 1 1 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 EGD84549.2 - 0.54 10.9 2.3 2.8 8.6 0.4 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain PsiA PF06952.11 EGD84551.2 - 0.074 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 PsiA protein p450 PF00067.22 EGD84552.1 - 4.6e-28 98.2 0.0 1.2e-27 96.8 0.0 1.7 1 1 1 2 2 2 1 Cytochrome P450 G_glu_transpept PF01019.21 EGD84553.2 - 3.7e-131 438.4 0.0 2.9e-129 432.1 0.0 2.0 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Pkinase PF00069.25 EGD84554.1 - 5.8e-66 222.6 0.0 7.3e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84554.1 - 1.6e-30 106.3 0.0 2.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGD84554.1 - 0.0088 15.0 0.0 0.024 13.6 0.0 1.8 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGD84554.1 - 0.055 12.8 0.1 0.11 11.8 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGD84554.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.5 3 1 0 3 3 3 0 Phosphotransferase enzyme family Pam16 PF03656.13 EGD84555.1 - 5.1e-06 26.5 0.2 1.1e-05 25.4 0.2 1.6 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 EGD84555.1 - 0.00044 20.3 0.0 0.00067 19.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 EGD84555.1 - 0.0017 17.9 0.9 0.0017 17.9 0.9 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3918) Ribosomal_L24e PF01246.20 EGD84556.1 - 1.2e-30 105.5 5.5 3.9e-30 103.9 5.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e DUF4820 PF16091.5 EGD84556.1 - 0.039 13.3 3.9 0.053 12.9 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4192 PF13830.6 EGD84556.1 - 0.13 12.3 0.4 0.14 12.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) APP_N PF02177.16 EGD84558.1 - 0.047 14.0 0.7 0.12 12.8 0.7 1.7 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding zf-H2C2_2 PF13465.6 EGD84560.1 - 3.6e-05 24.0 3.3 3.6e-05 24.0 3.3 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGD84560.1 - 4.6e-05 23.7 2.8 4.6e-05 23.7 2.8 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD84560.1 - 0.00015 22.3 1.7 0.00015 22.3 1.7 3.7 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGD84560.1 - 0.0037 17.2 1.3 0.011 15.7 1.3 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGD84560.1 - 0.0052 17.0 0.7 0.0052 17.0 0.7 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 EGD84560.1 - 0.0088 16.3 3.2 0.026 14.8 3.2 1.9 1 0 0 1 1 1 1 C2H2-type zinc ribbon Pkinase PF00069.25 EGD84562.2 - 6.4e-13 48.7 0.0 1.3e-10 41.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Fungal_trans PF04082.18 EGD84563.1 - 1.3e-28 99.8 0.1 2.4e-28 98.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD84563.1 - 6.9e-11 42.1 13.4 1.3e-10 41.2 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 EGD84563.1 - 0.074 13.2 1.5 0.1 12.8 0.2 1.9 2 0 0 2 2 2 0 Gal4-like dimerisation domain PHD PF00628.29 EGD84565.1 - 2.5e-10 40.1 7.8 5.8e-10 38.9 7.8 1.7 1 0 0 1 1 1 1 PHD-finger Aldolase_II PF00596.21 EGD84567.2 - 6.5e-34 117.5 0.0 8e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Drf_FH1 PF06346.12 EGD84568.1 - 2.6 7.8 15.6 0.18 11.6 3.5 3.1 3 0 0 3 3 3 0 Formin Homology Region 1 Med31 PF05669.12 EGD84569.1 - 2.2e-31 107.7 0.1 2.6e-31 107.5 0.1 1.1 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.11 EGD84570.2 - 5.7e-21 75.7 3.7 2e-20 74.0 0.5 2.2 2 0 0 2 2 2 1 Pal1 cell morphology protein Xan_ur_permease PF00860.20 EGD84571.2 - 1.4e-26 93.2 30.6 2.8e-24 85.6 29.7 3.0 2 1 0 2 2 2 2 Permease family MAGE PF01454.19 EGD84572.2 - 3.3e-17 62.9 0.0 4.7e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 MAGE family DUF2997 PF11211.8 EGD84572.2 - 0.011 15.5 1.0 0.068 13.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) Ank_3 PF13606.6 EGD84573.1 - 3.5e-10 39.2 0.1 0.0021 18.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EGD84573.1 - 1.3e-09 38.5 0.0 3.6e-09 37.1 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD84573.1 - 1e-08 35.6 0.5 1.6e-06 28.6 0.0 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGD84573.1 - 9.1e-08 32.2 0.1 0.0003 21.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EGD84573.1 - 2.7e-07 30.7 0.4 0.024 14.9 0.2 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Glyco_hydro_97 PF10566.9 EGD84573.1 - 0.043 13.1 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 PPR PF01535.20 EGD84573.1 - 0.15 12.4 0.7 0.42 11.0 0.7 1.8 1 0 0 1 1 1 0 PPR repeat PhyH PF05721.13 EGD84574.1 - 6.2e-22 78.9 0.0 7.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EGD84574.1 - 0.025 13.3 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) AA_permease_2 PF13520.6 EGD84575.1 - 1.2e-34 119.9 52.3 1.5e-34 119.6 52.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD84575.1 - 3.7e-06 25.8 45.2 4.9e-06 25.4 45.2 1.1 1 0 0 1 1 1 1 Amino acid permease Aminotran_1_2 PF00155.21 EGD84577.1 - 5.2e-18 65.4 0.0 6.5e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGD84577.1 - 4.4e-05 22.4 0.0 0.0062 15.4 0.0 2.5 1 1 1 2 2 2 2 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 EGD84577.1 - 0.002 17.2 0.0 0.003 16.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGD84577.1 - 0.23 10.7 0.1 2.6 7.2 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family PhyH PF05721.13 EGD84578.1 - 2.2e-18 67.3 0.0 3.6e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AMP-binding PF00501.28 EGD84579.1 - 1.7e-93 313.6 0.0 2.9e-93 312.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EGD84579.1 - 6.1e-87 291.4 0.2 1.6e-86 290.0 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGD84579.1 - 4e-60 204.0 1.2 8.2e-60 203.0 1.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EGD84579.1 - 2.1e-57 193.9 0.0 7.8e-56 188.8 0.0 2.7 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 EGD84579.1 - 7.4e-46 156.4 0.0 1.5e-44 152.1 0.0 2.7 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EGD84579.1 - 2e-38 131.0 0.1 5.2e-38 129.7 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EGD84579.1 - 1.3e-20 73.5 0.0 1.9e-11 44.1 0.0 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EGD84579.1 - 2.8e-13 50.3 0.0 1.6e-11 44.6 0.0 2.8 3 0 0 3 3 2 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EGD84579.1 - 2.7e-12 46.7 0.0 4.7e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EGD84579.1 - 1.3e-08 34.6 0.0 7.9e-06 25.5 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase AMP-binding_C PF13193.6 EGD84579.1 - 1.4e-08 35.5 0.0 3.9e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 EGD84579.1 - 1.4e-06 27.6 0.0 0.024 13.8 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EGD84579.1 - 4e-06 26.5 0.0 0.0014 18.1 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGD84579.1 - 1.8e-05 23.9 0.0 0.19 10.7 0.1 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 EGD84579.1 - 0.00028 20.3 0.3 0.00056 19.3 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain SLS PF14611.6 EGD84579.1 - 0.089 12.6 0.1 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator NmrA PF05368.13 EGD84579.1 - 0.11 12.1 0.2 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Peptidase_S24 PF00717.23 EGD84580.1 - 0.00062 19.7 0.0 0.0035 17.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_C47 PF05543.13 EGD84580.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Staphopain peptidase C47 Ank_2 PF12796.7 EGD84581.1 - 1.5e-06 28.7 0.0 3.2e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGD84581.1 - 3.2e-05 24.0 0.2 0.0056 17.1 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EGD84581.1 - 4.8e-05 23.8 0.0 0.00023 21.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGD84581.1 - 0.049 14.1 0.3 0.95 10.0 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat Macro PF01661.21 EGD84583.1 - 9e-35 119.3 0.0 1.6e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Macro domain GATA PF00320.27 EGD84585.1 - 3.3e-15 55.4 5.3 6.2e-15 54.5 5.3 1.5 1 0 0 1 1 1 1 GATA zinc finger Carla_C4 PF01623.17 EGD84585.1 - 0.073 13.0 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein zinc_ribbon_9 PF14369.6 EGD84585.1 - 0.41 10.9 1.6 0.92 9.8 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon MT0933_antitox PF14013.6 EGD84587.1 - 0.47 10.8 5.9 2.9 8.3 3.6 2.6 1 1 1 2 2 2 0 MT0933-like antitoxin protein ThrE PF06738.12 EGD84589.1 - 8.6e-66 221.7 11.5 1.5e-61 207.9 0.8 2.5 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EGD84589.1 - 5.5e-09 36.3 11.7 5.5e-09 36.3 11.7 3.1 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE Ank_4 PF13637.6 EGD84595.2 - 1.3e-12 48.0 0.1 1.2e-06 28.9 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGD84595.2 - 1.3e-09 38.5 0.0 1.8e-05 25.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGD84595.2 - 7.1e-08 32.1 0.1 1.2e-05 25.3 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EGD84595.2 - 7e-07 29.4 0.1 1.6e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGD84595.2 - 1.5e-06 28.4 0.6 1.2e-05 25.6 0.0 2.8 3 1 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 EGD84595.2 - 0.0013 18.6 0.1 0.015 15.1 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain WHEP-TRS PF00458.20 EGD84595.2 - 0.13 12.4 0.3 0.3 11.3 0.3 1.5 1 0 0 1 1 1 0 WHEP-TRS domain DUF4407 PF14362.6 EGD84595.2 - 6.5 6.0 7.6 31 3.8 7.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GCS PF03074.16 EGD84597.2 - 1.8e-175 583.6 0.0 2.2e-175 583.3 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.11 EGD84597.2 - 0.012 15.6 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) DUF2811 PF10929.8 EGD84597.2 - 0.12 12.7 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) CBS PF00571.28 EGD84598.2 - 0.065 13.7 0.1 0.11 13.0 0.1 1.3 1 0 0 1 1 1 0 CBS domain CBS PF00571.28 EGD84599.2 - 3.1e-08 34.0 0.0 1.4e-05 25.4 0.0 2.9 3 0 0 3 3 3 2 CBS domain DUF2183 PF09949.9 EGD84602.1 - 3.1e-32 110.9 0.0 9.8e-32 109.2 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF3885 PF13021.6 EGD84602.1 - 0.13 12.4 0.1 0.37 10.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) ADH_zinc_N_2 PF13602.6 EGD84603.2 - 9.1e-22 78.5 0.0 1.5e-21 77.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGD84603.2 - 8.7e-06 25.7 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 EGD84603.2 - 0.068 12.9 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) GPP34 PF05719.11 EGD84605.2 - 2.6e-29 102.7 0.2 3.1e-29 102.5 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.25 EGD84606.2 - 1.6e-11 44.4 0.2 2.6e-11 43.7 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EGD84606.2 - 4e-05 23.8 0.2 5.7e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier Fer4 PF00037.27 EGD84607.1 - 1.7e-13 49.8 16.5 6.1e-08 32.2 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGD84607.1 - 1.5e-12 47.9 10.0 2.4e-12 47.2 10.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGD84607.1 - 8.8e-10 39.4 9.9 0.00011 23.0 0.9 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EGD84607.1 - 1.3e-09 38.0 31.2 5.1e-06 26.5 12.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGD84607.1 - 1.7e-08 34.8 2.6 0.00036 20.9 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGD84607.1 - 2.9e-08 33.7 21.4 5e-06 26.5 12.3 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGD84607.1 - 3.3e-08 33.6 9.6 6.8e-08 32.6 9.7 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EGD84607.1 - 1.5e-06 28.0 17.1 0.00039 20.4 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EGD84607.1 - 4.8e-06 26.3 11.8 0.0097 16.0 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EGD84607.1 - 9e-06 25.8 11.4 0.00029 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EGD84607.1 - 0.00036 21.0 11.6 0.04 14.5 12.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EGD84607.1 - 0.01 16.0 5.7 0.48 10.7 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 EGD84607.1 - 0.065 13.8 15.0 0.74 10.4 4.3 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EGD84607.1 - 0.088 13.0 9.0 1.2 9.4 1.6 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 EGD84607.1 - 0.15 12.2 5.9 0.57 10.4 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 EGD84607.1 - 0.24 12.4 15.5 0.42 11.7 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EGD84607.1 - 1 10.3 12.1 2.3 9.1 1.6 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain SURF6 PF04935.12 EGD84608.2 - 2.5e-50 171.1 32.4 2.5e-50 171.1 32.4 3.8 2 1 1 3 3 3 1 Surfeit locus protein 6 Rick_17kDa_Anti PF05433.15 EGD84610.1 - 3.9e-05 23.4 11.5 3.9e-05 23.4 11.5 2.9 3 1 0 3 3 3 1 Glycine zipper 2TM domain Acyl_transf_3 PF01757.22 EGD84612.1 - 8e-40 136.9 32.0 1e-39 136.6 32.0 1.1 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.15 EGD84613.2 - 1.2e-12 48.3 0.2 2.6e-12 47.2 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Ribosomal_S2 PF00318.20 EGD84614.2 - 1.1e-65 220.8 0.0 1.2e-64 217.5 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S2 Ribosomal_L22 PF00237.19 EGD84615.1 - 0.16 12.2 0.7 1.2 9.4 0.7 2.1 1 1 0 1 1 1 0 Ribosomal protein L22p/L17e Zn_clus PF00172.18 EGD84615.1 - 0.19 11.9 5.7 0.14 12.3 1.9 2.1 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 EGD84616.1 - 2.6e-56 187.5 0.1 1.8e-18 66.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP_EFTU PF00009.27 EGD84617.1 - 7.8e-32 110.4 5.1 2.8e-30 105.3 5.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGD84617.1 - 1.5e-28 99.0 2.0 3.9e-28 97.6 0.5 2.4 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EGD84617.1 - 1e-10 41.7 0.1 2.3e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 EGD84617.1 - 4.5e-10 39.2 0.0 2.5e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 EGD84617.1 - 2.1e-05 24.8 1.7 0.041 14.3 0.2 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Arf PF00025.21 EGD84617.1 - 0.0002 20.9 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGD84617.1 - 0.00087 18.8 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGD84617.1 - 0.0022 18.0 2.8 0.074 12.9 0.2 2.7 1 1 1 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EGD84617.1 - 0.013 15.1 0.4 0.039 13.5 0.4 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 EGD84617.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 EGD84617.1 - 0.044 13.7 1.0 0.18 11.7 0.1 2.5 2 1 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 EGD84617.1 - 0.084 12.9 0.0 11 6.0 0.1 2.8 1 1 1 2 2 2 0 Dynamin family ExbD PF02472.16 EGD84617.1 - 0.092 12.9 0.2 0.55 10.4 0.0 2.2 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR PduV-EutP PF10662.9 EGD84617.1 - 0.11 12.2 0.2 0.35 10.6 0.2 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation HNH PF01844.23 EGD84619.1 - 0.003 17.7 3.7 0.0058 16.8 3.7 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EGD84619.1 - 0.45 10.4 1.7 4.5 7.2 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease EI24 PF07264.11 EGD84620.2 - 5e-12 46.4 0.4 6.7e-12 46.0 0.4 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ceramidase_alk PF04734.13 EGD84622.1 - 4.6e-202 672.2 0.0 5.4e-202 671.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EGD84622.1 - 9.8e-58 194.7 0.1 1.5e-57 194.1 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal BCAS2 PF05700.11 EGD84623.1 - 5.4e-66 222.2 3.9 6e-66 222.1 3.9 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Kelch_5 PF13854.6 EGD84624.2 - 2.8e-15 55.9 0.7 1.8e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 EGD84624.2 - 1.5e-09 37.7 1.3 0.0041 17.1 0.2 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EGD84624.2 - 1.8e-06 28.0 2.9 0.018 15.3 0.2 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 EGD84624.2 - 5.6e-06 26.5 4.6 0.00098 19.3 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EGD84624.2 - 9e-05 22.0 5.1 0.024 14.2 0.2 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 EGD84624.2 - 0.0044 16.9 0.1 0.072 13.1 0.1 2.7 2 0 0 2 2 2 1 Kelch motif Ten1 PF12658.7 EGD84625.1 - 2.1e-40 137.4 0.0 2.4e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 EGD84625.1 - 0.0035 17.0 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Snf7 PF03357.21 EGD84626.1 - 2.5e-32 111.8 18.0 2.5e-32 111.8 18.0 2.0 1 1 1 2 2 2 1 Snf7 Pecanex_C PF05041.15 EGD84626.1 - 0.0024 17.5 0.9 0.0033 17.0 0.9 1.1 1 0 0 1 1 1 1 Pecanex protein (C-terminus) CCDC24 PF15669.5 EGD84626.1 - 0.0028 17.6 5.3 0.0044 16.9 5.3 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family RTBV_P46 PF06216.11 EGD84626.1 - 0.75 8.6 3.2 1.1 8.1 2.7 1.4 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein DUF3138 PF11336.8 EGD84626.1 - 1.2 7.6 6.8 1.1 7.8 5.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Forkhead PF00250.18 EGD84627.1 - 4.8e-18 65.2 0.0 9.6e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EGD84627.1 - 0.00014 22.1 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain 2OG-FeII_Oxy_3 PF13640.6 EGD84628.1 - 2.9e-09 37.7 0.0 4.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily cNMP_binding PF00027.29 EGD84629.1 - 3e-39 133.0 0.0 9.3e-20 70.5 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain AMPK1_CBM PF16561.5 EGD84631.2 - 4e-17 62.2 0.0 1.1e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 EGD84631.2 - 0.019 15.3 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF4058 PF13267.6 EGD84632.2 - 0.012 15.1 0.0 0.053 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4058) EMC3_TMCO1 PF01956.16 EGD84635.1 - 0.049 13.4 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like GRP PF07172.11 EGD84635.1 - 0.056 14.1 0.8 0.085 13.6 0.8 1.4 1 1 0 1 1 1 0 Glycine rich protein family FeoB_associated PF12669.7 EGD84635.1 - 0.15 12.5 1.2 0.27 11.7 1.2 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein TMEMspv1-c74-12 PF11044.8 EGD84635.1 - 0.22 11.5 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF4307 PF14155.6 EGD84635.1 - 0.41 10.5 8.4 2.7 7.9 3.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) DUF1768 PF08719.11 EGD84636.2 - 3e-46 157.6 0.0 3.5e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pkinase PF00069.25 EGD84638.1 - 1.9e-24 86.4 0.0 3.6e-24 85.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84638.1 - 1e-08 34.8 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD84638.1 - 0.0018 17.1 0.1 0.0026 16.6 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGD84638.1 - 0.086 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YoeB_toxin PF06769.14 EGD84638.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 YoeB-like toxin of bacterial type II toxin-antitoxin system FTA2 PF13095.6 EGD84638.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.16 EGD84639.1 - 1.6e-32 112.8 24.7 1.6e-32 112.8 24.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD84639.1 - 4.8e-32 111.4 23.0 2.2e-29 102.6 23.0 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter BT1 PF03092.16 EGD84639.1 - 0.011 14.0 0.3 0.025 12.8 0.3 1.6 1 0 0 1 1 1 0 BT1 family PAP2_3 PF14378.6 EGD84641.2 - 1.2e-23 83.8 10.2 1.5e-23 83.4 10.2 1.1 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 EGD84641.2 - 1.1e-09 38.1 4.6 1.6e-09 37.6 4.6 1.3 1 0 0 1 1 1 1 PAP2 superfamily LCAT PF02450.15 EGD84643.2 - 9.5e-101 337.8 0.0 1.3e-100 337.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EGD84643.2 - 0.0015 19.2 0.0 0.0036 18.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 EGD84643.2 - 0.044 13.3 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) LIDHydrolase PF10230.9 EGD84643.2 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Acetyltransf_1 PF00583.25 EGD84644.1 - 6.8e-19 68.2 0.0 1.1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGD84644.1 - 6.8e-12 45.4 0.0 1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGD84644.1 - 1.5e-11 44.5 0.0 2.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD84644.1 - 2.4e-11 43.5 0.0 3.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EGD84644.1 - 9e-08 32.9 0.0 1.2e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGD84644.1 - 1.5e-06 28.0 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGD84644.1 - 1.4e-05 25.2 0.1 3.6e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGD84644.1 - 0.0003 20.8 0.0 0.00055 20.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EGD84644.1 - 0.0033 17.6 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EGD84644.1 - 0.029 14.3 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Mis14 PF08641.12 EGD84647.1 - 4.1e-23 82.2 5.2 1.1e-22 80.8 5.2 1.7 1 0 0 1 1 1 1 Kinetochore protein Mis14 like CRAL_TRIO PF00650.20 EGD84648.1 - 1.9e-38 131.7 0.0 2.6e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGD84648.1 - 5e-07 29.8 0.3 5e-07 29.8 0.3 2.4 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGD84648.1 - 0.0015 18.7 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CDC45 PF02724.14 EGD84648.1 - 0.04 12.2 0.5 0.047 12.0 0.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 EGD84648.1 - 0.32 11.2 4.6 0.91 9.7 4.5 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 EGD84648.1 - 0.56 9.1 1.4 0.78 8.6 1.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 EGD84648.1 - 0.63 10.5 6.5 1 9.8 6.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RasGAP PF00616.19 EGD84649.1 - 1e-35 123.4 0.0 2.2e-35 122.2 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGD84649.1 - 4.8e-32 111.0 5.6 1.4e-31 109.5 5.6 1.8 1 0 0 1 1 1 1 RasGAP C-terminus MarR PF01047.22 EGD84649.1 - 0.079 12.9 0.3 0.33 10.9 0.1 2.2 2 0 0 2 2 2 0 MarR family DUF1647 PF07801.11 EGD84649.1 - 0.12 12.1 0.9 0.34 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) RsbU_N PF08673.10 EGD84649.1 - 0.28 11.3 3.8 0.74 10.0 0.3 2.8 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain DNA_pol_A_exo1 PF01612.20 EGD84650.1 - 8e-41 139.7 0.5 1.3e-40 139.0 0.5 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EGD84650.1 - 2.2e-31 108.4 0.9 6.8e-30 103.6 1.1 2.7 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 EGD84650.1 - 1.3e-11 44.3 0.6 2.9e-11 43.2 0.1 2.0 2 0 0 2 2 2 1 HRDC domain AATF-Che1 PF13339.6 EGD84650.1 - 1.9 9.2 4.9 0.37 11.5 0.5 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF3446 PF11928.8 EGD84650.1 - 3.9 7.9 8.9 0.76 10.1 1.3 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain UPF0203 PF05254.12 EGD84651.2 - 8.8e-22 77.1 6.1 6e-20 71.3 2.9 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) COX17 PF05051.13 EGD84651.2 - 0.00016 21.9 1.0 0.0004 20.7 1.0 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EGD84651.2 - 0.011 15.7 4.4 0.38 10.8 0.1 2.9 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like TFIIA PF03153.13 EGD84652.2 - 0.19 11.7 18.4 0.24 11.4 18.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mucin PF01456.17 EGD84652.2 - 2 8.4 19.6 3 7.8 19.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 EGD84652.2 - 3.8 5.4 3.5 4.7 5.1 3.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Gpi1 PF05024.15 EGD84653.2 - 2.5e-75 252.7 9.6 4.2e-75 252.0 9.6 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MutS_V PF00488.21 EGD84654.1 - 3.1e-82 275.2 0.1 5.4e-82 274.4 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGD84654.1 - 4.3e-37 128.2 0.5 1.4e-36 126.5 0.2 2.0 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EGD84654.1 - 1.1e-23 84.0 0.1 4.6e-23 82.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EGD84654.1 - 1.4e-19 70.2 0.4 5.1e-19 68.4 0.4 2.1 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 EGD84654.1 - 5.7e-17 62.0 0.0 5.7e-16 58.7 0.0 2.4 2 0 0 2 2 2 1 MutS domain I zf-C2H2 PF00096.26 EGD84656.2 - 4.2e-05 23.8 11.7 0.017 15.6 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGD84656.2 - 0.00012 22.4 5.8 0.00031 21.0 3.8 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGD84656.2 - 0.00079 20.1 11.1 0.083 13.8 2.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger COG5 PF10392.9 EGD84658.1 - 6.7e-38 129.8 1.0 2.3e-37 128.1 0.0 2.4 3 0 0 3 3 3 1 Golgi transport complex subunit 5 SYS1 PF09801.9 EGD84659.1 - 6.4e-54 182.0 7.8 7.5e-54 181.8 7.8 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.12 EGD84659.1 - 0.028 14.4 2.6 0.028 14.4 2.6 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 COX6B PF02297.17 EGD84660.1 - 1.9e-23 82.5 4.0 2.3e-23 82.2 4.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Swi6_N PF18530.1 EGD84660.1 - 0.058 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Swi6 N-terminal domain CHCH PF06747.13 EGD84660.1 - 0.14 12.3 2.1 2 8.6 0.7 2.5 2 1 0 2 2 2 0 CHCH domain RRM_1 PF00076.22 EGD84661.2 - 2.7e-09 36.7 0.0 4.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGD84661.2 - 0.0078 15.8 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.20 EGD84662.2 - 1.6e-20 73.2 0.7 2.3e-20 72.6 0.7 1.2 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 EGD84662.2 - 0.0073 16.7 0.2 0.011 16.1 0.2 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit protein U3_assoc_6 PF08640.11 EGD84663.1 - 9.3e-29 99.3 0.9 9.3e-29 99.3 0.9 2.1 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 DUF4464 PF14713.6 EGD84663.1 - 0.0065 16.1 0.1 0.0095 15.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) TPR_14 PF13428.6 EGD84663.1 - 0.029 15.2 9.0 0.11 13.4 0.4 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.10 EGD84663.1 - 0.053 12.7 0.2 0.1 11.7 0.1 1.4 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference Apolipoprotein PF01442.18 EGD84665.1 - 0.00041 20.3 0.3 0.00051 20.0 0.3 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Syntaxin PF00804.25 EGD84665.1 - 0.052 13.2 0.4 0.061 13.0 0.4 1.2 1 0 0 1 1 1 0 Syntaxin DUF883 PF05957.13 EGD84665.1 - 0.73 10.5 4.7 0.96 10.1 2.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Pannexin_like PF12534.8 EGD84665.1 - 0.85 8.6 1.5 1 8.4 1.5 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 CDT1_C PF16679.5 EGD84666.1 - 5.4e-19 68.4 0.3 1.2e-18 67.3 0.3 1.6 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Lactamase_B_6 PF16661.5 EGD84667.2 - 1.5e-54 184.4 0.0 3.3e-54 183.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EGD84667.2 - 4.9e-46 157.0 0.1 4.9e-46 157.0 0.1 2.5 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EGD84667.2 - 3.1e-16 59.6 0.0 1.1e-15 57.9 0.0 2.0 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 EGD84667.2 - 3.9e-12 45.9 0.0 9.8e-12 44.6 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain tRNA-synt_2 PF00152.20 EGD84669.2 - 1.3e-35 123.0 0.0 1.5e-34 119.6 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) Gti1_Pac2 PF09729.9 EGD84672.1 - 1.7e-45 155.3 1.3 3.1e-38 131.7 0.1 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family DUF2434 PF10361.9 EGD84673.1 - 3e-121 403.9 7.0 3.7e-121 403.6 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) DKCLD PF08068.12 EGD84673.1 - 0.24 11.5 0.6 0.5 10.5 0.0 1.8 2 0 0 2 2 2 0 DKCLD (NUC011) domain TMEM220 PF15071.6 EGD84673.1 - 0.33 11.7 2.1 0.56 11.0 0.5 2.2 2 0 0 2 2 2 0 Transmembrane family 220, helix Fungal_trans_2 PF11951.8 EGD84676.1 - 1.1e-69 235.2 0.1 1.4e-69 234.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD84676.1 - 1.5e-09 37.8 10.0 2.7e-09 37.0 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 EGD84676.1 - 2.1 8.5 10.0 7.2 6.9 10.0 2.0 1 0 0 1 1 1 0 AT hook motif ABC_tran PF00005.27 EGD84678.1 - 1.3e-49 168.3 0.1 3.7e-25 89.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EGD84678.1 - 2.6e-48 164.2 33.9 1.7e-25 89.7 13.6 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 EGD84678.1 - 5.3e-11 42.9 5.8 0.0057 16.5 0.1 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGD84678.1 - 2.5e-09 36.9 0.2 0.0053 16.2 0.1 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGD84678.1 - 1.5e-08 35.4 0.9 0.00041 20.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGD84678.1 - 3e-08 34.2 0.1 0.0021 18.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGD84678.1 - 4e-07 30.1 5.1 0.0096 15.8 1.5 2.5 2 1 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGD84678.1 - 2.5e-06 27.1 2.7 0.079 12.7 1.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EGD84678.1 - 4.7e-06 26.6 0.3 0.039 13.9 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 EGD84678.1 - 4.2e-05 23.8 0.2 0.8 10.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 EGD84678.1 - 7.3e-05 22.8 0.1 0.0067 16.4 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EGD84678.1 - 0.00021 21.6 0.9 0.18 12.1 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EGD84678.1 - 0.00024 20.9 0.5 0.29 10.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EGD84678.1 - 0.00026 21.4 0.6 1.2 9.6 0.1 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EGD84678.1 - 0.00048 19.8 2.8 0.28 10.8 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EGD84678.1 - 0.00081 19.8 0.4 2.1 8.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_15 PF13175.6 EGD84678.1 - 0.00095 19.0 0.2 9.6 5.8 0.2 3.2 3 0 0 3 3 3 0 AAA ATPase domain DnaB_C PF03796.15 EGD84678.1 - 0.0013 18.2 0.2 1.5 8.1 0.1 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA_19 PF13245.6 EGD84678.1 - 0.0016 18.8 0.5 0.3 11.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGD84678.1 - 0.002 17.8 0.7 0.37 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGD84678.1 - 0.0038 17.2 0.4 4.4 7.3 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EGD84678.1 - 0.0045 16.1 0.1 1 8.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Roc PF08477.13 EGD84678.1 - 0.0089 16.2 1.5 0.93 9.7 0.3 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGD84678.1 - 0.023 14.8 4.0 0.2 11.7 0.7 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 EGD84678.1 - 0.03 14.2 0.9 4.9 7.0 0.3 2.7 3 0 0 3 3 2 0 NTPase AAA_17 PF13207.6 EGD84678.1 - 0.031 14.7 1.2 5 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EGD84678.1 - 0.031 14.0 0.9 2.1 8.0 0.3 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGD84678.1 - 0.032 14.8 0.1 3.4 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGD84678.1 - 0.036 13.8 1.2 8 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EGD84678.1 - 0.067 12.4 0.5 9.2 5.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 EGD84678.1 - 0.077 13.2 0.3 6.2 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EGD84678.1 - 0.1 12.3 0.0 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.14 EGD84678.1 - 0.1 12.5 1.3 6.7 6.6 0.3 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.12 EGD84678.1 - 0.1 12.0 2.2 4.4 6.7 0.5 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_11 PF13086.6 EGD84678.1 - 0.12 12.1 0.2 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EGD84678.1 - 0.16 11.7 0.3 22 4.7 0.1 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGD84678.1 - 0.17 11.6 1.1 2 8.1 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 EGD84678.1 - 0.17 11.3 1.7 6.7 6.2 0.4 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EGD84678.1 - 0.19 11.0 0.8 10 5.3 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin TIP49 PF06068.13 EGD84678.1 - 0.31 10.2 0.6 5.2 6.2 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_35 PF14516.6 EGD84678.1 - 0.33 9.7 0.6 5.8 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Bys1 PF04681.12 EGD84679.1 - 1.5e-06 28.2 0.2 1.9e-06 27.9 0.2 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thaumatin PF00314.17 EGD84679.1 - 0.0043 16.7 0.5 0.011 15.4 0.3 1.6 1 1 0 1 1 1 1 Thaumatin family Sec23_trunk PF04811.15 EGD84680.2 - 3.4e-49 167.6 0.0 1.7e-48 165.3 0.0 1.9 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGD84680.2 - 1e-22 79.9 0.0 2.2e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGD84680.2 - 1.9e-17 63.8 0.0 5e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGD84680.2 - 2.2e-15 56.4 4.5 4.4e-15 55.4 4.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGD84680.2 - 3e-06 27.0 0.0 6.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat AA_permease_2 PF13520.6 EGD84681.2 - 1.6e-55 188.7 44.8 1.9e-55 188.5 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD84681.2 - 4.7e-18 65.0 36.0 6.5e-18 64.6 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease Collectrin PF16959.5 EGD84681.2 - 0.31 10.8 0.0 0.31 10.8 0.0 2.1 3 0 0 3 3 3 0 Renal amino acid transporter DUF2721 PF11026.8 EGD84681.2 - 0.55 10.1 0.0 0.55 10.1 0.0 4.4 5 2 1 6 6 6 0 Protein of unknown function (DUF2721) RRM_1 PF00076.22 EGD84682.2 - 1.1e-13 50.8 0.0 2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup54 PF13874.6 EGD84682.2 - 0.021 14.9 0.2 0.04 14.0 0.2 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 MOZ_SAS PF01853.18 EGD84683.1 - 7.6e-64 214.7 0.0 1.1e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGD84683.1 - 1e-15 57.1 0.3 1.8e-15 56.3 0.3 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Cpn60_TCP1 PF00118.24 EGD84684.1 - 2.3e-161 537.8 1.2 2.6e-161 537.6 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nop PF01798.18 EGD84685.1 - 2.8e-87 292.0 0.0 2.8e-87 292.0 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGD84685.1 - 4e-18 65.6 0.1 4e-18 65.6 0.1 2.5 3 0 0 3 3 3 1 NOP5NT (NUC127) domain Rrn6 PF10214.9 EGD84685.1 - 0.0055 15.3 0.3 0.0063 15.1 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor RP-C_C PF11800.8 EGD84685.1 - 0.068 13.3 11.5 0.21 11.7 0.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region RNA_polI_A34 PF08208.11 EGD84685.1 - 0.079 13.0 34.3 0.14 12.2 34.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YL1 PF05764.13 EGD84685.1 - 0.23 11.6 27.4 0.34 11.0 27.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein GAGA_bind PF06217.12 EGD84685.1 - 2 8.7 14.2 4.4 7.5 14.2 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family CobT PF06213.12 EGD84685.1 - 3.5 7.0 22.7 3.9 6.8 21.1 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF3767 PF12597.8 EGD84687.1 - 7.4e-33 112.4 0.4 1.5e-32 111.4 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) DUF1744 PF08490.12 EGD84688.2 - 4.3e-150 499.7 0.8 6.6e-150 499.1 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EGD84688.2 - 4.2e-40 137.9 0.0 1.5e-39 136.0 0.0 2.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EGD84688.2 - 7.6e-17 61.2 0.8 7.2e-13 48.0 0.0 4.5 4 1 0 4 4 4 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EGD84688.2 - 8.4e-10 38.7 0.8 2.3e-09 37.2 0.1 2.1 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EGD84688.2 - 1.9e-05 24.7 0.0 8.4e-05 22.6 0.0 2.2 1 0 0 1 1 1 1 RNase_H superfamily Pkinase PF00069.25 EGD84689.1 - 5e-71 239.2 0.0 6.4e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84689.1 - 3.2e-28 98.7 0.0 4.3e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD84689.1 - 2.4e-07 30.4 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGD84689.1 - 0.00014 20.8 0.0 0.00023 20.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGD84689.1 - 0.00056 19.9 0.1 0.00079 19.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGD84689.1 - 0.00061 19.2 0.1 0.001 18.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AMMECR1 PF01871.17 EGD84691.1 - 1.3e-39 135.5 0.0 2.2e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 AMMECR1 DUF4880 PF16220.5 EGD84691.1 - 0.023 14.6 0.7 0.049 13.5 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) SGT1 PF07093.11 EGD84693.2 - 1.5e-42 145.9 7.3 2.5e-31 108.8 0.0 2.1 1 1 1 2 2 2 2 SGT1 protein PACT_coil_coil PF10495.9 EGD84694.2 - 8.7e-12 45.5 2.5 8.7e-12 45.5 2.5 6.2 5 1 0 5 5 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TMF_DNA_bd PF12329.8 EGD84694.2 - 2.3e-08 33.9 15.6 2.3e-08 33.9 15.6 15.3 7 4 8 16 16 16 4 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 EGD84694.2 - 0.011 16.3 31.6 0.011 16.3 31.6 7.0 1 1 7 8 8 8 0 Fez1 Pox_A_type_inc PF04508.12 EGD84694.2 - 0.014 15.3 2.1 0.014 15.3 2.1 10.0 10 1 1 11 11 11 0 Viral A-type inclusion protein repeat UME PF08064.13 EGD84694.2 - 2.1 8.3 4.4 3.9 7.4 0.0 3.6 4 1 0 4 4 4 0 UME (NUC010) domain AAA PF00004.29 EGD84695.2 - 3.2e-43 147.3 0.0 5.6e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD84695.2 - 5.2e-06 26.2 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGD84695.2 - 9.1e-06 25.5 0.0 1.7e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGD84695.2 - 1.3e-05 25.6 0.1 7.6e-05 23.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EGD84695.2 - 4.9e-05 23.4 0.0 0.00029 20.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGD84695.2 - 6.2e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EGD84695.2 - 0.00012 21.4 0.0 0.00017 20.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EGD84695.2 - 0.00016 21.9 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EGD84695.2 - 0.00016 21.7 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGD84695.2 - 0.00017 21.9 0.1 0.005 17.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGD84695.2 - 0.00038 19.7 0.0 0.0024 17.1 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EGD84695.2 - 0.00081 19.9 0.0 0.0018 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGD84695.2 - 0.0009 19.4 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGD84695.2 - 0.002 18.5 0.0 0.007 16.7 0.0 2.0 1 1 1 2 2 2 1 RNA helicase AAA_24 PF13479.6 EGD84695.2 - 0.0039 16.9 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGD84695.2 - 0.0091 15.5 0.0 0.059 12.9 0.0 2.2 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 EGD84695.2 - 0.012 15.2 0.1 0.51 9.9 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 EGD84695.2 - 0.016 15.7 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGD84695.2 - 0.017 15.0 0.0 0.26 11.2 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 EGD84695.2 - 0.026 13.9 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EGD84695.2 - 0.035 13.5 0.0 5.8 6.2 0.0 2.3 1 1 1 2 2 2 0 KaiC ATPase_2 PF01637.18 EGD84695.2 - 0.054 13.4 0.1 0.5 10.2 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 EGD84695.2 - 0.054 12.6 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ParB PF08775.10 EGD84695.2 - 0.055 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 ParB family PhoH PF02562.16 EGD84695.2 - 0.061 12.8 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.11 EGD84695.2 - 0.069 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.26 EGD84695.2 - 0.078 12.7 0.0 0.23 11.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Prefoldin_2 PF01920.20 EGD84696.1 - 2.3e-22 78.9 17.9 3.1e-22 78.5 17.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 EGD84696.1 - 4.3e-06 26.7 7.2 6e-06 26.2 7.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 EGD84696.1 - 0.00049 20.0 0.6 0.00049 20.0 0.6 2.5 2 1 0 2 2 2 1 Prefoldin subunit Spc24 PF08286.11 EGD84696.1 - 0.0034 17.6 16.1 0.033 14.4 6.7 2.1 1 1 1 2 2 2 2 Spc24 subunit of Ndc80 Taxilin PF09728.9 EGD84696.1 - 0.0069 15.6 13.2 0.02 14.1 5.9 2.1 2 0 0 2 2 2 1 Myosin-like coiled-coil protein YabA PF06156.13 EGD84696.1 - 0.008 16.8 8.2 0.41 11.3 0.2 2.1 2 0 0 2 2 2 1 Initiation control protein YabA CENP-H PF05837.12 EGD84696.1 - 0.013 15.9 7.9 0.47 10.9 0.1 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Siah-Interact_N PF09032.11 EGD84696.1 - 0.014 15.7 10.3 0.72 10.2 3.8 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal SOGA PF11365.8 EGD84696.1 - 0.015 16.4 3.5 2.5 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein SOGA Spc7 PF08317.11 EGD84696.1 - 0.017 14.0 14.7 0.026 13.4 14.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Osmo_CC PF08946.10 EGD84696.1 - 0.024 14.9 4.6 0.024 14.9 4.6 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil CCDC144C PF14915.6 EGD84696.1 - 0.025 13.7 13.6 0.17 11.0 3.2 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region SlyX PF04102.12 EGD84696.1 - 0.031 14.9 0.5 0.031 14.9 0.5 2.9 2 1 0 2 2 2 0 SlyX HDV_ag PF01517.18 EGD84696.1 - 0.037 13.8 1.6 0.11 12.3 1.6 1.7 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen TMF_TATA_bd PF12325.8 EGD84696.1 - 0.038 14.2 14.1 0.4 10.9 5.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding XhlA PF10779.9 EGD84696.1 - 0.043 14.0 2.4 0.043 14.0 2.4 2.2 2 1 0 2 2 2 0 Haemolysin XhlA TolA_bind_tri PF16331.5 EGD84696.1 - 0.05 13.7 14.9 0.82 9.8 6.3 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation Swi5 PF07061.11 EGD84696.1 - 0.052 13.6 10.4 1.7 8.8 5.3 2.4 2 0 0 2 2 2 0 Swi5 NPV_P10 PF05531.12 EGD84696.1 - 0.057 13.9 10.4 1.6 9.3 3.4 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PHM7_cyt PF14703.6 EGD84696.1 - 0.061 13.5 8.1 0.11 12.7 8.1 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter ABC_tran_CTD PF16326.5 EGD84696.1 - 0.091 13.0 22.5 0.29 11.4 6.3 3.3 2 2 1 3 3 3 0 ABC transporter C-terminal domain Uso1_p115_C PF04871.13 EGD84696.1 - 0.093 13.1 16.9 0.19 12.1 8.1 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region EzrA PF06160.12 EGD84696.1 - 0.11 10.6 15.5 0.049 11.8 3.6 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA End3 PF12761.7 EGD84696.1 - 0.13 12.4 11.7 0.18 12.0 11.7 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF3727 PF12527.8 EGD84696.1 - 0.14 12.4 4.2 1.1 9.5 2.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3727) Golgin_A5 PF09787.9 EGD84696.1 - 0.14 11.6 11.9 0.2 11.1 11.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Apt1 PF10351.9 EGD84696.1 - 0.18 10.6 8.0 0.23 10.3 8.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DegS PF05384.11 EGD84696.1 - 0.18 11.2 10.5 0.52 9.8 2.8 2.2 2 0 0 2 2 2 0 Sensor protein DegS COG5 PF10392.9 EGD84696.1 - 0.19 11.9 5.3 3.2 7.9 1.2 2.1 1 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF4407 PF14362.6 EGD84696.1 - 0.2 11.0 12.2 0.42 9.9 12.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 EGD84696.1 - 0.21 12.1 23.1 0.89 10.1 3.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 EGD84696.1 - 0.21 11.6 17.1 0.2 11.7 8.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 EGD84696.1 - 0.22 11.3 21.6 0.66 9.8 3.7 3.2 2 1 1 3 3 3 0 Septum formation initiator GAS PF13851.6 EGD84696.1 - 0.28 10.5 17.1 0.17 11.2 6.9 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 EGD84696.1 - 0.3 11.2 17.6 0.41 10.8 7.3 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF5082 PF16888.5 EGD84696.1 - 0.32 11.3 15.9 1.1 9.6 15.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) MIP-T3_C PF17749.1 EGD84696.1 - 0.33 10.9 12.9 0.045 13.7 3.8 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Sas10_Utp3 PF04000.15 EGD84696.1 - 0.38 11.4 3.7 9.4 6.9 1.1 2.3 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Rx_N PF18052.1 EGD84696.1 - 0.38 11.0 11.6 0.45 10.8 3.7 2.3 2 1 0 2 2 2 0 Rx N-terminal domain betaPIX_CC PF16523.5 EGD84696.1 - 0.45 10.4 10.8 0.23 11.3 3.8 2.3 2 1 0 2 2 2 0 betaPIX coiled coil DUF1664 PF07889.12 EGD84696.1 - 0.48 10.5 12.9 2.2 8.4 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4349 PF14257.6 EGD84696.1 - 0.49 9.8 15.6 0.26 10.7 1.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) Tropomyosin PF00261.20 EGD84696.1 - 0.52 9.6 15.5 0.55 9.6 2.2 2.0 2 0 0 2 2 2 0 Tropomyosin DHR10 PF18595.1 EGD84696.1 - 0.52 10.4 20.2 0.79 9.8 8.3 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain WEMBL PF05701.11 EGD84696.1 - 0.56 8.8 15.8 0.13 10.9 1.9 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light FlaC_arch PF05377.11 EGD84696.1 - 0.57 10.6 11.3 1.6 9.2 1.0 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) MtrG PF04210.13 EGD84696.1 - 0.61 10.0 5.5 0.44 10.4 1.3 2.5 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G AAA_13 PF13166.6 EGD84696.1 - 0.69 8.5 14.8 0.021 13.5 1.5 2.0 1 1 1 2 2 2 0 AAA domain Occludin_ELL PF07303.13 EGD84696.1 - 0.82 10.4 8.1 1.4 9.7 4.8 2.1 1 1 1 2 2 2 0 Occludin homology domain Laminin_II PF06009.12 EGD84696.1 - 1 9.4 11.7 2 8.4 0.8 2.1 1 1 0 2 2 2 0 Laminin Domain II ERM PF00769.19 EGD84696.1 - 1 9.1 18.9 2 8.2 18.9 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Sec34 PF04136.15 EGD84696.1 - 1.1 9.2 8.8 4.1 7.3 3.1 2.1 2 0 0 2 2 2 0 Sec34-like family DUF4164 PF13747.6 EGD84696.1 - 1.4 9.3 11.8 1.5 9.2 5.5 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) CENP-F_leu_zip PF10473.9 EGD84696.1 - 1.8 8.6 16.0 4.2 7.4 4.9 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SKA2 PF16740.5 EGD84696.1 - 2.3 8.0 12.6 4.4 7.1 4.6 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 CorA PF01544.18 EGD84696.1 - 2.4 7.4 8.0 0.52 9.6 0.9 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Jnk-SapK_ap_N PF09744.9 EGD84696.1 - 2.5 8.3 15.8 6 7.1 15.8 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF724 PF05266.14 EGD84696.1 - 2.6 7.8 12.1 0.91 9.3 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Chibby PF14645.6 EGD84696.1 - 2.7 8.4 7.2 1.1 9.7 0.2 2.7 1 1 2 3 3 3 0 Chibby family OmpH PF03938.14 EGD84696.1 - 2.8 8.3 25.9 1.3e+02 2.9 25.9 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) BRE1 PF08647.11 EGD84696.1 - 2.9 8.0 17.9 0.68 10.0 2.1 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Flagellin_N PF00669.20 EGD84696.1 - 2.9 8.0 10.3 0.72 10.0 4.1 2.0 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Rootletin PF15035.6 EGD84696.1 - 3.1 7.8 13.3 0.53 10.3 6.5 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4200 PF13863.6 EGD84696.1 - 3.2 8.2 19.1 7.6 7.0 4.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GrpE PF01025.19 EGD84696.1 - 3.4 7.3 14.4 4 7.1 5.8 2.1 2 0 0 2 2 2 0 GrpE HMMR_N PF15905.5 EGD84696.1 - 3.7 6.9 17.5 27 4.1 17.5 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Snapin_Pallidin PF14712.6 EGD84696.1 - 3.8 8.0 12.8 1.1 9.7 0.9 2.3 2 0 0 2 2 2 0 Snapin/Pallidin FapA PF03961.13 EGD84696.1 - 4.2 5.9 13.3 21 3.6 13.3 1.8 1 1 0 1 1 1 0 Flagellar Assembly Protein A CENP-Q PF13094.6 EGD84696.1 - 4.4 7.5 14.6 8.6 6.5 14.6 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ACCA PF03255.14 EGD84696.1 - 4.4 7.2 9.5 6.2 6.7 0.8 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Fib_alpha PF08702.10 EGD84696.1 - 4.5 7.4 14.7 1.4e+02 2.6 14.7 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 EGD84696.1 - 5.1 7.5 16.5 1.5 9.2 3.3 2.1 1 1 1 2 2 2 0 Fez1 THOC7 PF05615.13 EGD84696.1 - 5.5 7.3 17.5 0.37 11.1 4.1 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 DUF641 PF04859.12 EGD84696.1 - 6 7.2 12.9 3.4 8.0 2.7 2.2 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 EGD84696.1 - 6.1 6.0 10.9 7.3 5.7 10.1 1.5 1 1 0 1 1 1 0 TMPIT-like protein DUF2408 PF10303.9 EGD84696.1 - 6.1 7.4 10.6 23 5.5 10.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Peptidase_S49_N PF08496.10 EGD84696.1 - 6.9 6.7 10.8 13 5.9 10.7 1.4 1 1 0 1 1 1 0 Peptidase family S49 N-terminal ATG16 PF08614.11 EGD84696.1 - 7.2 6.8 16.8 5.2 7.2 6.5 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 EGD84696.1 - 7.8 6.8 6.3 24 5.3 0.2 2.2 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4337 PF14235.6 EGD84696.1 - 7.8 6.6 11.4 5 7.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) UPF0242 PF06785.11 EGD84696.1 - 8.3 6.5 22.2 1.5 8.9 9.1 2.0 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PCRF PF03462.18 EGD84696.1 - 8.7 6.2 10.7 24 4.7 10.5 1.7 1 1 0 1 1 1 0 PCRF domain iPGM_N PF06415.13 EGD84697.1 - 4.7e-78 261.6 0.0 6.3e-78 261.1 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EGD84697.1 - 7.2e-71 238.4 0.0 8.3e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EGD84697.1 - 0.00077 18.9 0.0 0.025 14.0 0.0 2.4 2 1 0 2 2 2 1 Sulfatase Alk_phosphatase PF00245.20 EGD84697.1 - 0.02 13.9 0.1 0.08 11.9 0.0 1.8 2 0 0 2 2 2 0 Alkaline phosphatase Med9 PF07544.13 EGD84698.1 - 1.4e-14 53.9 0.1 2.6e-14 53.1 0.1 1.6 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 EGD84698.1 - 0.54 10.5 3.6 2.6 8.3 0.1 2.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex SHMT PF00464.19 EGD84699.1 - 1.1e-206 686.1 0.0 1.3e-206 685.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EGD84699.1 - 6.9e-06 25.5 0.0 2.4e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGD84699.1 - 0.00082 18.4 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGD84699.1 - 0.13 10.8 0.0 0.24 9.9 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3040 PF11239.8 EGD84699.1 - 0.16 12.3 0.1 0.32 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) RNA_polI_A34 PF08208.11 EGD84700.1 - 1.9e-41 142.4 2.8 1.9e-41 142.4 2.8 3.1 2 1 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 EGD84700.1 - 5.6 5.1 33.5 0.34 9.2 5.6 2.1 2 0 0 2 2 2 0 CDC45-like protein CLP1_P PF16575.5 EGD84701.2 - 3.2e-31 108.6 0.0 1.4e-30 106.5 0.0 1.9 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF3095 PF11294.8 EGD84701.2 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) AAA_33 PF13671.6 EGD84701.2 - 0.029 14.5 0.4 0.21 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGD84701.2 - 0.052 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 EGD84701.2 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Septin PF00735.18 EGD84701.2 - 0.22 10.8 0.0 0.99 8.6 0.0 1.9 2 0 0 2 2 2 0 Septin Folliculin PF11704.8 EGD84704.2 - 7.2e-50 169.4 0.1 3e-49 167.4 0.0 2.0 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport CSN8_PSD8_EIF3K PF10075.9 EGD84706.1 - 2.7e-45 153.9 0.0 3.7e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PDCD2_C PF04194.13 EGD84707.1 - 3.9e-42 144.3 1.0 8.3e-42 143.2 0.0 2.0 2 1 1 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain LysM PF01476.20 EGD84709.2 - 4e-07 30.0 0.0 0.018 15.1 0.0 3.7 4 0 0 4 4 4 2 LysM domain Prenylcys_lyase PF07156.14 EGD84711.1 - 7.6e-96 321.4 0.0 1e-95 320.9 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 EGD84711.1 - 1.6e-14 54.0 0.0 2.6e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGD84711.1 - 3e-11 43.4 0.0 7.3e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGD84711.1 - 8.7e-08 32.1 0.1 0.00082 19.0 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGD84711.1 - 0.0046 16.2 0.0 0.1 11.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGD84711.1 - 0.0055 16.7 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 EGD84711.1 - 0.012 14.8 0.2 0.46 9.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Glyco_transf_28 PF03033.20 EGD84712.1 - 1.1e-29 103.2 0.0 6.1e-29 100.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EGD84712.1 - 0.0037 16.1 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Prefoldin PF02996.17 EGD84713.1 - 5.2e-30 103.8 0.1 9e-30 103.1 0.1 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EGD84713.1 - 0.0016 18.4 0.9 0.009 16.0 0.1 2.2 2 0 0 2 2 2 1 Prefoldin subunit Halogen_Hydrol PF10112.9 EGD84713.1 - 0.036 14.1 0.1 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein FlaC_arch PF05377.11 EGD84713.1 - 0.079 13.4 0.5 2.3 8.7 0.1 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) LMP PF04778.12 EGD84713.1 - 0.1 12.5 0.2 6.7 6.6 0.0 2.1 2 0 0 2 2 2 0 LMP repeated region End3 PF12761.7 EGD84713.1 - 0.11 12.6 2.1 0.22 11.7 0.1 2.1 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DMPK_coil PF08826.10 EGD84713.1 - 0.16 12.1 3.3 2.6 8.2 0.8 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like LcrG PF07216.12 EGD84713.1 - 1.5 8.8 4.8 0.62 10.0 1.8 1.9 2 1 0 2 2 2 0 LcrG protein Vma12 PF11712.8 EGD84714.1 - 1.6e-42 144.8 0.0 2.5e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase HPP PF04982.13 EGD84714.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 HPP family ATP-synt_I PF03899.15 EGD84714.1 - 0.14 12.5 1.3 0.17 12.3 0.1 1.7 2 0 0 2 2 2 0 ATP synthase I chain Amidohydro_1 PF01979.20 EGD84715.2 - 3.6e-06 26.5 0.0 4.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGD84715.2 - 6.4e-06 25.9 0.0 1.7e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase family 5-nucleotidase PF06189.12 EGD84715.2 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 5'-nucleotidase Glyco_transf_24 PF18404.1 EGD84716.2 - 1.6e-149 496.6 0.9 2.2e-149 496.2 0.9 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_15 PF18403.1 EGD84716.2 - 2.3e-43 148.6 0.0 3.8e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EGD84716.2 - 1.8e-41 140.6 0.0 4.1e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_14 PF18402.1 EGD84716.2 - 0.00029 20.9 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EGD84716.2 - 0.00048 19.8 0.0 0.00076 19.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF1416 PF07210.12 EGD84716.2 - 0.21 11.5 0.0 0.49 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) PhzC-PhzF PF02567.16 EGD84719.2 - 0.00038 20.0 0.5 0.01 15.3 0.1 2.1 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein KH_6 PF15985.5 EGD84720.1 - 7.2e-16 58.3 0.1 1.3e-15 57.5 0.1 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 EGD84720.1 - 0.011 15.6 0.4 0.072 13.0 0.1 2.4 2 0 0 2 2 2 0 Exosome complex exonuclease Rrp40 N-terminal domain Rpp20 PF12328.8 EGD84722.1 - 1.7e-46 157.6 4.9 2.5e-46 157.0 4.9 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EGD84722.1 - 1.1e-15 57.1 0.5 2.2e-15 56.2 0.5 1.5 1 0 0 1 1 1 1 Alba SRP14 PF02290.15 EGD84722.1 - 0.08 13.3 0.4 0.16 12.3 0.4 1.5 1 0 0 1 1 1 0 Signal recognition particle 14kD protein UAA PF08449.11 EGD84723.2 - 2e-05 24.0 10.5 2.4e-05 23.7 10.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGD84723.2 - 0.00042 20.5 20.5 0.00084 19.5 7.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family SBP_bac_1 PF01547.25 EGD84723.2 - 0.024 14.6 0.1 6.4 6.6 0.1 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein HSP70 PF00012.20 EGD84724.1 - 2.4e-83 280.4 3.4 9.1e-83 278.4 0.6 2.0 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EGD84724.1 - 4.1e-11 42.3 0.9 6.7e-11 41.6 0.9 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 EGD84724.1 - 0.0024 17.0 0.1 2 7.3 0.0 2.5 2 1 0 2 2 2 2 Type IV pilus assembly protein PilM; PI3K_1B_p101 PF10486.9 EGD84724.1 - 0.02 12.7 0.7 0.033 12.0 0.7 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Cwf_Cwc_15 PF04889.12 EGD84724.1 - 0.049 13.4 9.7 0.09 12.5 9.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peripla_BP_6 PF13458.6 EGD84724.1 - 0.051 13.2 0.6 0.086 12.5 0.5 1.4 1 1 0 1 1 1 0 Periplasmic binding protein FAM176 PF14851.6 EGD84724.1 - 0.057 13.1 2.6 0.13 11.9 2.6 1.6 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 EGD84724.1 - 0.16 12.4 15.2 0.36 11.3 15.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 EGD84724.1 - 0.45 10.8 7.9 1.2 9.4 7.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TFB6 PF17110.5 EGD84724.1 - 0.54 10.0 2.6 1.1 9.0 2.6 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RXT2_N PF08595.11 EGD84724.1 - 0.58 10.2 6.8 0.12 12.4 3.1 1.7 2 0 0 2 2 1 0 RXT2-like, N-terminal GCIP PF13324.6 EGD84724.1 - 0.61 9.6 5.7 1.5 8.4 5.7 1.6 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 EGD84724.1 - 1.8 6.5 13.6 2.8 5.9 13.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EGD84724.1 - 1.9 7.8 14.1 3 7.1 14.1 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 EGD84724.1 - 4.5 7.7 14.0 8.4 6.9 14.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 EGD84724.1 - 6.1 6.6 8.8 0.79 9.5 4.6 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CDC45 PF02724.14 EGD84724.1 - 6.4 4.9 8.1 9.2 4.4 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 EGD84724.1 - 6.7 6.5 10.9 2.5 7.9 7.9 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region RRN3 PF05327.11 EGD84724.1 - 7.4 5.0 5.6 12 4.3 5.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.9 EGD84724.1 - 7.5 5.6 17.9 13 4.8 17.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rogdi_lz PF10259.9 EGD84725.1 - 2.9e-84 282.7 0.0 3.3e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein BNR_2 PF13088.6 EGD84726.1 - 2.5e-12 46.7 0.0 5.8e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 EGD84726.1 - 1.7e-10 40.7 0.0 2.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain Rsm22 PF09243.10 EGD84727.1 - 3.6e-29 101.9 0.0 2.3e-28 99.3 0.0 2.2 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 EGD84727.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DASH_Spc19 PF08287.11 EGD84728.1 - 2e-49 167.5 1.6 2.7e-49 167.1 1.6 1.2 1 0 0 1 1 1 1 Spc19 LPD30 PF18850.1 EGD84728.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 ADIP PF11559.8 EGD84728.1 - 0.3 11.1 6.3 1.4 9.0 1.4 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding ATP-synt_J PF04911.12 EGD84729.1 - 9e-27 92.4 0.5 1e-26 92.2 0.5 1.0 1 0 0 1 1 1 1 ATP synthase j chain LRR_8 PF13855.6 EGD84732.1 - 2.4e-09 36.8 0.8 5.7e-09 35.6 0.8 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EGD84732.1 - 3.8e-06 27.1 0.8 1e-05 25.8 0.3 2.0 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) MGC-24 PF05283.11 EGD84734.1 - 1.1 9.7 5.0 1.5 9.3 5.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin LysM PF01476.20 EGD84737.1 - 3.8e-19 68.5 0.0 1.3e-06 28.4 0.0 3.3 3 0 0 3 3 3 3 LysM domain DUF4106 PF13388.6 EGD84737.1 - 0.0011 18.3 22.8 0.0018 17.6 22.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) HTH_7 PF02796.15 EGD84737.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EGD84737.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain UPF0203 PF05254.12 EGD84737.1 - 0.097 12.9 4.0 7.2 6.9 0.2 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) Ndc1_Nup PF09531.10 EGD84737.1 - 3.6 6.2 9.3 4.9 5.7 9.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex14_N PF04695.13 EGD84737.1 - 4.7 7.8 22.8 2.2 8.9 19.9 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Romo1 PF10247.9 EGD84738.1 - 5.6e-28 97.1 16.6 7.2e-28 96.7 16.6 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 EGD84738.1 - 0.032 14.6 5.7 0.043 14.2 5.7 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.6 EGD84738.1 - 0.16 11.8 3.5 0.78 9.6 0.4 2.3 2 0 0 2 2 2 0 Glycine-zipper domain FHA PF00498.26 EGD84739.1 - 2.3e-16 59.9 0.0 4.4e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGD84739.1 - 0.0002 21.6 0.0 0.00058 20.1 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain MscS_porin PF12795.7 EGD84739.1 - 0.037 13.6 22.1 0.074 12.6 4.6 3.2 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Jnk-SapK_ap_N PF09744.9 EGD84739.1 - 0.28 11.4 15.2 0.48 10.6 4.3 2.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 T3SSipB PF16535.5 EGD84739.1 - 2.2 8.7 17.8 0.044 14.3 6.7 2.8 3 0 0 3 3 3 0 Type III cell invasion protein SipB GrpE PF01025.19 EGD84739.1 - 3.1 7.4 15.6 0.27 10.9 4.8 2.3 2 0 0 2 2 2 0 GrpE FAD_binding_3 PF01494.19 EGD84741.2 - 8.9e-13 48.2 0.0 2.6e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGD84741.2 - 0.0001 22.4 0.0 0.00027 21.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGD84741.2 - 0.00019 20.8 0.1 0.0067 15.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGD84741.2 - 0.0003 19.8 0.7 0.0004 19.4 0.1 1.5 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.24 EGD84741.2 - 0.0004 20.1 0.2 0.00063 19.4 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EGD84741.2 - 0.02 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1967 PF09269.11 EGD84741.2 - 0.02 14.8 0.8 0.12 12.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) NAD_binding_9 PF13454.6 EGD84741.2 - 0.041 13.9 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 EGD84741.2 - 0.05 12.8 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EGD84741.2 - 0.16 11.3 0.4 0.26 10.6 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EGD84741.2 - 0.18 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MCRA PF06100.11 EGD84741.2 - 0.19 10.5 0.1 0.3 9.8 0.1 1.2 1 0 0 1 1 1 0 MCRA family LysM PF01476.20 EGD84742.1 - 5.2e-06 26.4 0.0 8.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain Chitin_bind_1 PF00187.19 EGD84742.1 - 0.013 16.0 17.5 0.013 16.0 17.5 3.4 3 0 0 3 3 3 0 Chitin recognition protein DEC-1_N PF04625.13 EGD84742.1 - 1.6 7.7 3.8 2.5 7.0 3.8 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region EI24 PF07264.11 EGD84743.1 - 6.5e-13 49.3 4.3 9.7e-13 48.7 4.3 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF1772 PF08592.11 EGD84743.1 - 0.033 14.5 0.2 0.033 14.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) zf-RING_2 PF13639.6 EGD84744.2 - 3e-13 49.9 5.4 4.6e-13 49.3 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGD84744.2 - 2.5e-09 36.7 2.5 2.5e-09 36.7 2.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGD84744.2 - 3.8e-09 36.2 4.8 6e-09 35.6 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGD84744.2 - 5.3e-09 36.2 2.7 1.1e-08 35.3 2.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGD84744.2 - 1.2e-08 34.7 4.0 1.9e-08 34.0 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGD84744.2 - 9.2e-08 31.9 3.1 1.4e-07 31.3 3.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGD84744.2 - 2.5e-06 27.2 3.1 3.6e-06 26.7 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD84744.2 - 3.5e-06 26.9 2.3 7.2e-06 25.9 0.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGD84744.2 - 0.00042 20.3 0.7 0.00078 19.4 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGD84744.2 - 0.00088 19.1 3.1 0.0015 18.3 3.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGD84744.2 - 0.023 14.9 3.2 0.054 13.7 3.2 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EGD84744.2 - 0.04 14.1 3.0 0.11 12.7 3.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EGD84744.2 - 0.044 13.4 3.1 0.076 12.7 3.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EGD84744.2 - 0.21 11.7 4.3 0.48 10.6 4.3 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EGD84744.2 - 0.3 10.9 3.2 0.52 10.2 3.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 EGD84744.2 - 0.37 10.7 3.1 0.7 9.8 3.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 EGD84744.2 - 0.83 9.5 2.6 1.5 8.7 2.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 EGD84744.2 - 1.2 9.5 3.7 2.4 8.5 3.7 1.5 1 0 0 1 1 1 0 RING-like domain Raptor_N PF14538.6 EGD84746.2 - 1.6e-65 219.5 0.0 2.7e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.22 EGD84746.2 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Caspase domain HEAT PF02985.22 EGD84746.2 - 0.0041 17.2 1.0 0.75 10.2 0.0 3.6 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 EGD84746.2 - 0.007 16.7 0.0 0.029 14.8 0.0 2.0 1 0 0 1 1 1 1 HEAT repeats Atx10homo_assoc PF09759.9 EGD84746.2 - 0.0092 16.0 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain MerT PF02411.15 EGD84747.1 - 0.0037 17.3 0.1 0.0048 16.9 0.1 1.2 1 0 0 1 1 1 1 MerT mercuric transport protein DUF4396 PF14342.6 EGD84748.1 - 5.6e-45 153.2 2.9 7.8e-45 152.7 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Kelch_5 PF13854.6 EGD84750.1 - 2.4e-34 116.8 6.3 4.8e-09 36.0 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGD84750.1 - 4e-30 103.6 12.2 4.7e-08 32.9 1.3 6.5 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGD84750.1 - 1.3e-28 98.6 23.3 1.4e-07 31.6 0.6 7.2 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EGD84750.1 - 9e-28 95.6 4.2 2.2e-12 46.4 0.2 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 EGD84750.1 - 2.1e-25 88.1 9.0 8.7e-11 41.7 0.5 6.3 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGD84750.1 - 7.3e-23 79.6 7.3 1.2e-08 34.6 0.2 6.4 6 0 0 6 6 6 4 Kelch motif YabA PF06156.13 EGD84750.1 - 0.0082 16.8 2.4 0.0082 16.8 2.4 7.7 4 2 3 7 7 7 1 Initiation control protein YabA Vac_Fusion PF02346.16 EGD84750.1 - 2.4 7.8 13.9 30 4.4 0.0 5.6 5 1 1 6 6 6 0 Chordopoxvirus multifunctional envelope protein A27 Pkinase PF00069.25 EGD84751.1 - 6.1e-26 91.4 0.0 7.8e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84751.1 - 7.9e-14 51.6 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD84751.1 - 5.4e-09 35.3 0.0 7.6e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGD84751.1 - 0.00026 21.0 0.0 0.0016 18.4 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family bZIP_1 PF00170.21 EGD84752.1 - 8.3e-06 25.8 12.6 1.3e-05 25.2 12.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 EGD84752.1 - 2.7e-05 24.0 6.3 3.9e-05 23.5 6.3 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 EGD84752.1 - 0.0032 15.5 1.3 0.004 15.2 1.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family bZIP_Maf PF03131.17 EGD84752.1 - 0.019 15.5 10.7 0.032 14.8 10.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor CCDC106 PF15794.5 EGD84752.1 - 0.053 13.2 8.0 0.05 13.3 4.3 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 GAS PF13851.6 EGD84752.1 - 0.057 12.8 6.5 0.082 12.3 6.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Pox_A_type_inc PF04508.12 EGD84752.1 - 0.079 12.8 1.7 0.18 11.7 1.7 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TMF_TATA_bd PF12325.8 EGD84752.1 - 0.13 12.5 4.5 0.23 11.7 4.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1043 PF06295.12 EGD84752.1 - 0.14 12.1 2.7 0.31 11.0 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PAP1 PF08601.10 EGD84752.1 - 0.23 11.1 0.1 0.23 11.1 0.1 2.3 2 0 0 2 2 2 0 Transcription factor PAP1 bZIP_2 PF07716.15 EGD84752.1 - 0.38 10.9 16.7 0.61 10.2 15.6 1.8 1 1 1 2 2 2 0 Basic region leucine zipper CDC45 PF02724.14 EGD84752.1 - 3 6.0 6.8 4.1 5.6 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Phosducin PF02114.16 EGD84753.1 - 1.7e-15 56.7 0.1 2e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Phosducin Exog_C PF18026.1 EGD84753.1 - 0.71 10.0 5.7 7.3 6.7 2.3 2.4 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain Adaptin_N PF01602.20 EGD84754.2 - 2.3e-70 237.7 0.0 1.8e-69 234.7 0.0 2.0 1 1 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EGD84754.2 - 6.4e-60 201.7 1.4 1.3e-59 200.6 1.4 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EGD84754.2 - 2.3e-31 108.3 0.2 1.1e-30 106.1 0.0 2.2 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EGD84754.2 - 2.6e-17 63.0 0.7 1e-12 48.2 0.0 3.5 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 EGD84754.2 - 2.3e-06 27.8 3.2 0.0012 18.9 0.1 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGD84754.2 - 0.00072 19.6 4.0 0.33 11.3 0.3 4.5 5 0 0 5 5 5 1 HEAT repeat Alpha_adaptin_C PF02296.16 EGD84754.2 - 0.0025 18.0 0.0 0.0067 16.6 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain HEAT_PBS PF03130.16 EGD84754.2 - 0.013 16.1 2.6 1.9 9.4 0.1 3.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 EGD84754.2 - 0.049 14.1 1.0 0.18 12.4 0.4 2.3 2 0 0 2 2 2 0 HEAT-like repeat F-box-like PF12937.7 EGD84755.2 - 1.6e-10 40.7 1.5 2.9e-10 39.9 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGD84755.2 - 0.07 13.0 0.5 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 F-box domain Hydrolase_6 PF13344.6 EGD84756.1 - 1.3e-23 83.0 0.0 2.5e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGD84756.1 - 1e-15 57.5 0.0 5.4e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EGD84756.1 - 0.069 13.4 0.0 10 6.4 0.0 3.1 2 1 2 4 4 4 0 haloacid dehalogenase-like hydrolase FdtA PF05523.11 EGD84756.1 - 0.22 11.3 0.0 1.2 8.9 0.0 2.0 2 0 0 2 2 2 0 WxcM-like, C-terminal tRNA-synt_2 PF00152.20 EGD84757.1 - 3.2e-66 223.5 0.1 4.5e-66 223.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGD84757.1 - 8.9e-07 28.8 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain fn3_2 PF16893.5 EGD84757.1 - 0.18 12.0 0.1 22 5.3 0.0 2.6 1 1 1 2 2 2 0 Fibronectin type III domain SIP1 PF04938.12 EGD84758.1 - 2.3e-11 43.9 0.0 2.7e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF4149 PF13664.6 EGD84761.1 - 4.1e-27 94.5 1.3 4.1e-27 94.5 1.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 EGD84761.1 - 0.048 14.0 0.0 0.062 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Baculo_PEP_C PF04513.12 EGD84762.1 - 0.0012 18.9 20.9 1.5 8.8 0.2 6.6 2 1 5 7 7 7 2 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.6 EGD84762.1 - 0.0091 16.0 16.4 0.033 14.2 1.5 5.1 3 1 1 4 4 4 2 FlxA-like protein HEPN_AbiU2 PF18734.1 EGD84762.1 - 0.016 14.7 1.7 0.044 13.3 0.1 2.7 2 0 0 2 2 2 0 AbiU2 DUF2408 PF10303.9 EGD84762.1 - 0.096 13.3 30.8 0.055 14.0 4.9 5.7 2 1 2 5 5 5 0 Protein of unknown function (DUF2408) DUF730 PF05325.11 EGD84762.1 - 0.14 12.2 5.8 0.16 12.0 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF730) Corona_S2 PF01601.16 EGD84762.1 - 0.6 8.5 3.1 0.6 8.5 0.2 2.2 3 0 0 3 3 3 0 Coronavirus S2 glycoprotein ROS_MUCR PF05443.11 EGD84762.1 - 0.96 9.5 10.2 1.1 9.3 0.6 4.5 3 2 0 3 3 3 0 ROS/MUCR transcriptional regulator protein Lectin_N PF03954.14 EGD84762.1 - 3.7 7.3 22.0 0.84 9.4 0.1 5.0 3 1 2 5 5 5 0 Hepatic lectin, N-terminal domain MitMem_reg PF13012.6 EGD84762.1 - 5.1 7.6 9.6 3.1e+02 1.8 0.2 4.4 2 1 1 3 3 3 0 Maintenance of mitochondrial structure and function DCB PF16213.5 EGD84762.1 - 7.2 6.2 15.0 1.7 8.3 1.3 3.7 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 Topoisom_bac PF01131.20 EGD84763.1 - 1.3e-101 340.6 0.0 1.7e-101 340.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EGD84763.1 - 8.8e-16 58.0 0.0 2.1e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DUF1295 PF06966.12 EGD84764.1 - 3.1e-40 138.2 6.8 4.8e-40 137.6 6.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EGD84764.1 - 0.27 11.7 0.0 0.27 11.7 0.0 2.5 3 1 1 4 4 4 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Peptidase_M41 PF01434.18 EGD84765.2 - 5.1e-67 225.4 1.4 6.3e-67 225.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 EGD84765.2 - 8.7e-42 142.7 0.0 2.5e-41 141.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD84765.2 - 8.5e-12 44.7 0.1 2.4e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EGD84765.2 - 6.6e-09 36.1 1.0 1.6e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 EGD84765.2 - 0.003 17.5 0.0 0.014 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGD84765.2 - 0.0034 17.8 0.2 0.16 12.4 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGD84765.2 - 0.0078 16.5 0.0 1.2 9.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EGD84765.2 - 0.021 14.5 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGD84765.2 - 0.024 13.9 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 EGD84765.2 - 0.03 14.0 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 EGD84765.2 - 2.4 8.6 5.7 2.4 8.6 0.0 3.4 3 1 0 3 3 3 0 AAA domain Fungal_trans PF04082.18 EGD84766.2 - 8.3e-24 84.0 0.0 8.3e-24 84.0 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain DUF4834 PF16118.5 EGD84766.2 - 0.0016 19.4 5.4 0.0018 19.2 3.5 2.2 2 0 0 2 2 1 1 Domain of unknown function (DUF4834) Hid1 PF12722.7 EGD84766.2 - 0.0093 14.2 15.9 0.013 13.7 15.9 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein TFIIA PF03153.13 EGD84766.2 - 0.013 15.6 26.6 0.018 15.1 26.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 EGD84766.2 - 0.041 12.3 0.4 0.055 11.9 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spt20 PF12090.8 EGD84766.2 - 0.043 13.4 36.4 0.068 12.8 36.4 1.3 1 0 0 1 1 1 0 Spt20 family TERB2 PF15101.6 EGD84766.2 - 0.051 13.6 14.3 0.082 13.0 14.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Bud13 PF09736.9 EGD84766.2 - 0.17 12.3 14.4 0.23 11.9 13.3 1.7 2 0 0 2 2 1 0 Pre-mRNA-splicing factor of RES complex Roughex PF06020.11 EGD84766.2 - 0.23 10.5 14.7 0.36 9.9 14.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Macoilin PF09726.9 EGD84766.2 - 0.24 9.9 13.3 0.34 9.4 13.3 1.1 1 0 0 1 1 1 0 Macoilin family CobT PF06213.12 EGD84766.2 - 0.33 10.3 16.8 0.5 9.7 16.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Folliculin PF11704.8 EGD84766.2 - 0.73 9.7 9.4 1.4 8.8 9.4 1.5 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport MDM10 PF12519.8 EGD84766.2 - 0.89 8.3 9.5 1.3 7.8 9.5 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Band_3_cyto PF07565.13 EGD84766.2 - 0.95 9.2 10.5 1.5 8.6 10.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2722 PF10846.8 EGD84766.2 - 1.1 8.1 29.1 0.12 11.3 24.9 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2722) FTO_NTD PF12933.7 EGD84766.2 - 1.1 8.4 10.1 1.9 7.6 10.1 1.3 1 0 0 1 1 1 0 FTO catalytic domain Peroxin-13_N PF04088.13 EGD84766.2 - 1.2 9.5 5.4 2.9 8.2 5.4 1.6 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Ndc1_Nup PF09531.10 EGD84766.2 - 1.3 7.6 17.4 2.3 6.8 17.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF702 PF05142.12 EGD84766.2 - 1.6 9.2 12.5 3.1 8.3 12.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) PAT1 PF09770.9 EGD84766.2 - 1.6 6.9 26.6 2.2 6.4 26.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.17 EGD84766.2 - 1.8 8.7 13.1 0.16 12.1 6.9 2.2 2 1 0 2 2 2 0 DDHD domain NARP1 PF12569.8 EGD84766.2 - 1.8 7.4 11.8 2.6 6.8 11.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CPSF100_C PF13299.6 EGD84766.2 - 1.9 8.7 10.5 3.1 7.9 10.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SRP-alpha_N PF04086.13 EGD84766.2 - 1.9 8.3 17.1 2.8 7.8 17.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.12 EGD84766.2 - 2.1 8.1 13.0 3.1 7.5 13.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.10 EGD84766.2 - 3.3 7.8 8.2 20 5.2 8.9 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Coilin_N PF15862.5 EGD84766.2 - 3.5 7.4 16.4 6.5 6.6 16.4 1.4 1 0 0 1 1 1 0 Coilin N-terminus DUF966 PF06136.13 EGD84766.2 - 4 7.1 15.3 5.7 6.6 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4175 PF13779.6 EGD84766.2 - 4.2 5.1 24.9 6 4.7 24.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Plasmodium_Vir PF05795.11 EGD84766.2 - 4.6 6.6 11.1 7.9 5.8 11.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CLN3 PF02487.17 EGD84766.2 - 4.7 6.1 7.5 7.7 5.4 7.5 1.3 1 0 0 1 1 1 0 CLN3 protein CDC45 PF02724.14 EGD84766.2 - 4.8 5.3 12.9 6.5 4.9 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EGD84766.2 - 5.1 5.7 18.8 8.6 5.0 18.8 1.3 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 EGD84766.2 - 5.8 5.6 11.2 7.9 5.2 11.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Gti1_Pac2 PF09729.9 EGD84766.2 - 5.9 6.9 12.3 11 6.0 12.3 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family EMC3_TMCO1 PF01956.16 EGD84766.2 - 7.1 6.3 7.3 4.5 7.0 5.2 1.7 2 0 0 2 2 1 0 Integral membrane protein EMC3/TMCO1-like Neur_chan_memb PF02932.16 EGD84766.2 - 7.4 6.6 11.4 13 5.8 11.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Lin-8 PF03353.15 EGD84766.2 - 7.9 5.9 22.6 12 5.3 22.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Borrelia_P83 PF05262.11 EGD84766.2 - 9.8 4.5 15.3 14 4.0 15.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein tRNA-synt_2b PF00587.25 EGD84769.1 - 2.4e-30 105.8 0.0 1.1e-28 100.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGD84769.1 - 6.9e-16 58.2 0.1 1.3e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EGD84769.1 - 5.3e-13 48.8 0.0 9.5e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EGD84769.1 - 0.0024 17.9 0.0 0.0072 16.3 0.0 1.7 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.14 EGD84770.1 - 8.6e-38 129.5 0.0 1e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region WSC PF01822.19 EGD84772.1 - 2.1e-08 34.2 8.7 4.2e-08 33.3 8.7 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 EGD84772.1 - 2.4e-06 26.9 3.3 5.2e-06 25.8 3.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LapA_dom PF06305.11 EGD84772.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2370 PF10176.9 EGD84774.1 - 3.7e-91 304.8 0.0 5.5e-91 304.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2561 PF10812.8 EGD84774.1 - 0.16 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) CoA_trans PF01144.23 EGD84776.1 - 3.3e-104 347.0 1.8 1.2e-64 217.6 0.4 2.0 2 0 0 2 2 2 2 Coenzyme A transferase MFS_1 PF07690.16 EGD84777.1 - 3.8e-19 68.8 62.3 8.6e-19 67.7 48.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tim17 PF02466.19 EGD84779.2 - 1.7e-08 34.8 3.9 3.5e-08 33.8 3.9 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 EGD84779.2 - 0.17 11.9 0.8 1.1 9.3 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF543) PH PF00169.29 EGD84780.2 - 9.8e-05 22.8 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF5344 PF17279.2 EGD84780.2 - 0.06 13.9 0.4 1.9 9.1 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5344) RRM_1 PF00076.22 EGD84781.1 - 2.5e-42 142.5 0.0 1.8e-17 62.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGD84781.1 - 0.00014 21.8 0.0 1.3 9.1 0.0 3.0 3 0 0 3 3 3 2 RNA binding motif RRM_5 PF13893.6 EGD84781.1 - 0.00099 18.7 0.0 0.4 10.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGD84781.1 - 0.052 13.6 0.1 3.9 7.6 0.0 3.3 3 1 0 3 3 3 0 Limkain b1 FmdA_AmdA PF03069.15 EGD84784.1 - 6.5e-58 196.4 0.0 1.1e-33 116.7 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family AA_permease_2 PF13520.6 EGD84785.1 - 3.8e-54 184.1 50.6 4.7e-54 183.8 50.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD84785.1 - 9.9e-21 73.9 42.9 1.4e-20 73.4 42.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3043 PF11241.8 EGD84785.1 - 1.6 8.7 7.0 3.7 7.6 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3043) Ost5 PF05251.12 EGD84787.1 - 0.25 11.6 5.3 0.1 12.8 1.5 2.2 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 COQ9 PF08511.11 EGD84788.1 - 7.6e-26 89.7 0.5 2.2e-25 88.2 0.1 1.9 2 0 0 2 2 2 1 COQ9 UvrA_inter PF17760.1 EGD84789.1 - 0.022 14.8 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 UvrA interaction domain WD40 PF00400.32 EGD84790.1 - 3.6e-08 33.9 0.3 0.46 11.4 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat DNA_methylase PF00145.17 EGD84791.1 - 6.8e-33 114.4 0.0 1.1e-32 113.7 0.0 1.3 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EGD84791.1 - 8.9e-06 25.6 0.3 0.0011 18.8 0.2 2.5 2 0 0 2 2 2 2 BAH domain RasGAP PF00616.19 EGD84792.1 - 3.9e-32 111.7 0.0 1.4e-20 73.9 0.0 3.5 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EGD84792.1 - 2.5e-07 30.9 0.0 1.6e-06 28.3 0.0 2.4 2 1 0 2 2 2 1 C2 domain APG9 PF04109.16 EGD84793.1 - 7.8e-208 691.3 11.8 9.3e-208 691.1 11.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_47 PF01532.20 EGD84794.2 - 5.2e-184 612.4 0.0 6.1e-184 612.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APH PF01636.23 EGD84795.2 - 1.8e-10 41.2 0.2 2.9e-09 37.2 0.2 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGD84795.2 - 0.00047 19.6 0.2 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 EGD84795.2 - 0.0027 16.6 0.0 0.0064 15.4 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Vac14_Fig4_bd PF11916.8 EGD84796.2 - 5.3e-76 254.3 11.8 1.5e-59 200.6 3.5 3.1 3 0 0 3 3 3 2 Vacuolar protein 14 C-terminal Fig4p binding HEAT_EZ PF13513.6 EGD84796.2 - 0.0012 19.3 1.2 0.017 15.6 0.0 2.9 2 1 0 2 2 2 1 HEAT-like repeat Cnd1 PF12717.7 EGD84796.2 - 0.0078 16.3 0.2 0.018 15.1 0.2 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGD84796.2 - 0.16 12.3 0.5 39 4.9 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat KAR9 PF08580.10 EGD84796.2 - 0.24 9.9 3.3 0.38 9.3 3.3 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SNF2_N PF00176.23 EGD84797.2 - 4e-35 121.2 0.0 5.6e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGD84797.2 - 2.6e-15 56.7 0.0 6.1e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EGD84797.2 - 4.8e-05 22.7 0.0 0.0003 20.1 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EGD84797.2 - 0.018 15.0 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-C2H2_jaz PF12171.8 EGD84799.1 - 5e-10 39.4 4.3 5e-10 39.4 4.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGD84799.1 - 0.023 15.0 1.3 0.034 14.5 1.3 1.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EGD84799.1 - 0.074 13.1 1.5 0.074 13.1 1.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGD84799.1 - 0.092 13.6 0.7 0.092 13.6 0.7 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 EGD84799.1 - 4.6 7.8 6.4 1.1 9.8 1.7 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Aconitase PF00330.20 EGD84800.1 - 2.1e-148 495.2 0.0 2.6e-148 494.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGD84800.1 - 2.6e-43 147.5 0.0 4.5e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain BLACT_WH PF17778.1 EGD84801.1 - 2.1e-18 66.0 0.1 3.7e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 EGD84801.1 - 6.6e-15 55.6 1.9 5.1e-14 52.7 1.9 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGD84801.1 - 1.4e-06 28.0 0.2 2.1e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGD84801.1 - 0.0093 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_transf_20 PF00982.21 EGD84802.1 - 6.3e-200 664.8 0.0 7.2e-200 664.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 EGD84802.1 - 0.014 15.1 0.2 0.039 13.6 0.0 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain UbiA PF01040.18 EGD84803.1 - 5.9e-17 61.8 3.1 7.1e-17 61.5 3.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Prenyltransf PF01255.19 EGD84804.2 - 2.7e-39 135.0 0.0 3.2e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Nucleos_tra2_C PF07662.13 EGD84808.1 - 7.5e-73 244.8 1.0 7.5e-73 244.8 1.0 3.5 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EGD84808.1 - 6.1e-23 81.2 4.7 6.1e-23 81.2 4.7 3.1 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus FA_desaturase PF00487.24 EGD84808.1 - 0.022 14.6 0.0 0.022 14.6 0.0 3.0 3 1 0 3 3 3 0 Fatty acid desaturase UQ_con PF00179.26 EGD84809.1 - 1.5e-48 164.0 0.0 1.8e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGD84809.1 - 0.00012 22.4 0.0 0.00019 21.7 0.0 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EGD84809.1 - 0.0032 17.2 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGD84809.1 - 0.0042 16.9 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain UFC1 PF08694.11 EGD84809.1 - 0.099 12.3 0.0 0.54 9.9 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 Pkinase PF00069.25 EGD84810.1 - 5e-61 206.4 0.0 1.7e-60 204.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84810.1 - 1.8e-26 93.0 0.0 2.6e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD84810.1 - 4.9e-10 39.2 0.0 6.6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGD84810.1 - 0.0032 16.9 0.0 0.032 13.6 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 EGD84811.2 - 8.4e-11 41.6 1.3 1.7e-10 40.6 1.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD84811.2 - 3.6e-09 36.3 0.3 7e-09 35.4 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGD84811.2 - 0.0062 16.4 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 F-box DHBP_synthase PF00926.19 EGD84812.1 - 5.6e-81 270.7 0.0 6.5e-81 270.5 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TFIIE_beta PF02186.15 EGD84813.2 - 1e-22 80.1 0.1 1.2e-21 76.8 0.0 2.5 2 1 0 2 2 2 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 EGD84813.2 - 4.3e-22 77.6 1.5 6.9e-22 76.9 0.3 2.0 3 0 0 3 3 3 1 TFA2 Winged helix domain 2 DUF1631 PF07793.11 EGD84813.2 - 0.19 10.1 4.4 0.031 12.7 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) Syntaxin_2 PF14523.6 EGD84813.2 - 0.38 11.2 0.1 0.38 11.2 0.1 2.3 3 0 0 3 3 3 0 Syntaxin-like protein TPR_MLP1_2 PF07926.12 EGD84814.2 - 4.9e-37 126.9 31.5 4.9e-37 126.9 31.5 14.0 5 5 8 14 14 14 7 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 EGD84814.2 - 0.0056 17.2 19.2 0.0056 17.2 19.2 9.7 1 1 8 9 9 9 5 Fez1 Rootletin PF15035.6 EGD84814.2 - 0.006 16.6 4.9 0.006 16.6 4.9 12.0 1 1 9 11 11 11 3 Ciliary rootlet component, centrosome cohesion Baculo_PEP_C PF04513.12 EGD84814.2 - 0.0077 16.3 6.2 0.0077 16.3 6.2 10.8 6 4 6 13 13 13 4 Baculovirus polyhedron envelope protein, PEP, C terminus Acid_PPase PF12689.7 EGD84815.1 - 3.2e-69 232.1 0.2 7.3e-69 230.9 0.0 1.7 2 0 0 2 2 2 1 Acid Phosphatase Hexapep PF00132.24 EGD84815.1 - 2.5e-08 33.3 8.1 0.0028 17.3 3.0 4.2 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGD84815.1 - 0.0008 19.1 4.8 0.035 13.9 2.4 3.3 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase LRR_4 PF12799.7 EGD84816.1 - 0.0002 21.7 2.3 0.00095 19.5 1.2 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGD84816.1 - 0.037 14.1 5.4 31 5.0 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 EGD84816.1 - 0.042 13.6 1.0 0.57 10.0 0.8 2.5 2 1 0 2 2 2 0 Leucine rich repeat GlcNAc PF11397.8 EGD84816.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) LRR_1 PF00560.33 EGD84816.1 - 0.21 12.3 0.6 1.1e+02 4.0 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat Nuc_sug_transp PF04142.15 EGD84819.1 - 4.4e-86 288.9 8.5 5.8e-86 288.5 8.5 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGD84819.1 - 4.8 7.4 31.8 0.026 14.7 8.8 2.9 2 2 0 2 2 2 0 EamA-like transporter family HORMA PF02301.18 EGD84822.1 - 3.3e-70 236.0 0.0 6.4e-70 235.0 0.0 1.5 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 EGD84822.1 - 0.0027 17.6 8.2 0.006 16.5 8.2 1.6 1 0 0 1 1 1 1 PHD-finger MarR_2 PF12802.7 EGD84822.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 MarR family PHD_2 PF13831.6 EGD84822.1 - 0.062 12.9 2.8 0.16 11.5 2.8 1.7 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.32 EGD84824.2 - 5.9e-41 137.7 17.1 2.8e-06 27.9 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EGD84824.2 - 1.9e-10 40.5 0.1 4.3e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD84824.2 - 2.6e-10 39.9 0.2 5.1e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EGD84824.2 - 2.2e-05 24.7 1.3 6.9 7.0 0.0 4.7 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD84824.2 - 5.8e-05 21.9 4.0 3.9 6.0 0.2 5.3 4 2 2 6 6 6 3 Nucleoporin Nup120/160 F-box_4 PF15966.5 EGD84824.2 - 0.0016 18.3 0.0 0.0048 16.8 0.0 1.8 1 0 0 1 1 1 1 F-box FliG_C PF01706.16 EGD84824.2 - 0.062 13.5 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 FliG C-terminal domain MMR_HSR1 PF01926.23 EGD84825.1 - 2e-17 63.3 0.0 3e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGD84825.1 - 1.2e-06 28.0 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EGD84825.1 - 3.1e-06 27.4 0.0 0.00027 21.0 0.0 2.3 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 EGD84825.1 - 8.7e-06 25.4 0.0 4.9e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGD84825.1 - 0.00024 21.0 0.7 0.00094 19.1 0.3 2.0 2 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EGD84825.1 - 0.0014 18.1 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 EGD84825.1 - 0.0019 17.6 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 EGD84825.1 - 0.0068 15.7 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Septin CLP1_P PF16575.5 EGD84825.1 - 0.081 12.7 0.1 3 7.6 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PduV-EutP PF10662.9 EGD84825.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 EGD84825.1 - 0.13 11.7 0.0 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Clat_adaptor_s PF01217.20 EGD84826.1 - 2.2e-42 144.3 0.0 3.5e-42 143.7 0.0 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Fur_reg_FbpA PF13076.6 EGD84827.2 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Fur-regulated basic protein A Ribosomal_L7Ae PF01248.26 EGD84828.1 - 3.5e-21 74.8 0.3 5.9e-21 74.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRP36 PF06102.12 EGD84828.1 - 0.012 15.6 0.5 0.012 15.6 0.5 2.1 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Cnd1 PF12717.7 EGD84829.1 - 4.6e-07 30.0 0.0 0.53 10.3 0.0 3.3 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGD84829.1 - 4.1e-06 26.6 0.1 1 9.8 0.0 4.8 5 0 0 5 5 4 2 HEAT repeat HEAT_2 PF13646.6 EGD84829.1 - 7e-05 23.1 0.1 0.027 14.9 0.1 3.7 2 1 2 4 4 4 1 HEAT repeats Adaptin_N PF01602.20 EGD84829.1 - 8.1e-05 21.4 0.4 0.00066 18.4 0.4 2.5 1 1 0 1 1 1 1 Adaptin N terminal region TAN PF11640.8 EGD84829.1 - 0.0015 18.7 1.4 0.013 15.6 0.0 3.0 2 1 0 2 2 2 1 Telomere-length maintenance and DNA damage repair Macoilin PF09726.9 EGD84829.1 - 0.0025 16.5 0.0 0.0025 16.5 0.0 1.5 2 0 0 2 2 2 1 Macoilin family DCB PF16213.5 EGD84829.1 - 0.045 13.4 0.1 0.32 10.7 0.0 2.4 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 Exonuc_VII_L PF02601.15 EGD84829.1 - 0.046 13.3 6.6 0.31 10.6 2.5 2.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit HEAT_EZ PF13513.6 EGD84829.1 - 0.052 14.1 0.7 1.5 9.4 0.2 3.3 4 0 0 4 4 2 0 HEAT-like repeat V-ATPase_H_C PF11698.8 EGD84829.1 - 0.1 12.7 0.1 3.8 7.6 0.0 3.0 3 0 0 3 3 3 0 V-ATPase subunit H G-gamma PF00631.22 EGD84829.1 - 0.2 11.7 0.9 0.78 9.8 0.9 2.1 1 0 0 1 1 1 0 GGL domain Atg14 PF10186.9 EGD84829.1 - 0.44 9.6 4.7 0.81 8.7 4.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 EGD84829.1 - 1 8.8 12.7 2.2 7.7 12.7 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 Proteasom_PSMB PF10508.9 EGD84829.1 - 1.1 7.7 3.7 9.4 4.6 0.0 2.4 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Spc7 PF08317.11 EGD84829.1 - 1.1 8.0 15.1 0.2 10.5 11.4 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein JIP_LZII PF16471.5 EGD84829.1 - 2.1 8.6 7.4 2.4 8.4 5.6 2.1 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II MCC-bdg_PDZ PF10506.9 EGD84829.1 - 2.8 8.0 6.6 3.9 7.6 2.6 2.9 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome HsbA PF12296.8 EGD84829.1 - 3.5 8.1 4.8 24 5.4 0.1 3.3 3 1 0 3 3 2 0 Hydrophobic surface binding protein A ADIP PF11559.8 EGD84829.1 - 4.2 7.4 16.0 12 6.0 16.0 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 EGD84829.1 - 4.3 7.8 16.2 0.41 11.1 10.2 2.1 2 0 0 2 2 2 0 Fez1 Latarcin PF10279.9 EGD84829.1 - 8 6.9 7.8 6.7 7.2 4.5 2.5 3 0 0 3 3 3 0 Latarcin precursor DUF4407 PF14362.6 EGD84829.1 - 8.6 5.6 14.7 0.79 9.0 8.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EGD84829.1 - 8.7 6.7 16.0 2 8.8 8.6 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1720 PF08226.11 EGD84832.2 - 6.7e-09 36.0 40.8 6.7e-09 36.0 40.8 5.4 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) UIM PF02809.20 EGD84832.2 - 0.0084 16.0 8.1 0.13 12.3 2.0 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif Chorismate_bind PF00425.18 EGD84833.2 - 8.5e-92 307.3 0.0 1.1e-91 307.0 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EGD84833.2 - 0.00015 22.0 0.7 1 9.5 0.2 3.7 3 1 1 4 4 4 2 Anthranilate synthase component I, N terminal region POR PF01558.18 EGD84833.2 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase WD40_alt PF14077.6 EGD84834.2 - 0.071 13.0 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif TPR_MLP1_2 PF07926.12 EGD84834.2 - 0.077 13.1 5.5 0.14 12.3 5.5 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phlebovirus_NSM PF07246.11 EGD84834.2 - 0.13 11.6 0.4 0.18 11.2 0.4 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M LisH PF08513.11 EGD84835.1 - 1.6e-06 27.9 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 LisH ANAPC4_WD40 PF12894.7 EGD84835.1 - 2.9e-06 27.5 0.2 0.0054 17.0 0.0 5.0 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGD84835.1 - 4.2e-06 27.4 0.6 2.8 8.9 0.0 5.5 5 1 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 EGD84835.1 - 0.82 9.7 7.3 24 5.0 0.1 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1751 PF08551.10 EGD84836.1 - 7.3e-29 100.3 0.5 7.3e-29 100.3 0.5 1.8 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EGD84836.1 - 8.2e-05 22.6 9.1 8.2e-05 22.6 9.1 1.9 2 0 0 2 2 2 1 Rhomboid family L51_S25_CI-B8 PF05047.16 EGD84837.2 - 2.8e-13 49.5 0.0 5.1e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LRS4 PF10422.9 EGD84837.2 - 0.24 10.9 3.0 0.34 10.5 3.0 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 tRNA-synt_1 PF00133.22 EGD84838.2 - 3.4e-34 118.1 0.0 2.1e-24 85.7 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGD84838.2 - 4.4e-15 55.3 0.0 5.3e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGD84838.2 - 1.7e-11 44.3 0.1 4.4e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGD84838.2 - 3.5e-07 29.9 0.0 6.9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EGD84838.2 - 0.032 13.2 0.0 0.19 10.6 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) Mito_carr PF00153.27 EGD84839.1 - 2e-65 216.8 5.7 5.6e-22 77.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PBP-Tp47_a PF14889.6 EGD84839.1 - 0.11 12.1 0.0 0.83 9.3 0.0 2.0 2 0 0 2 2 2 0 Penicillin-binding protein Tp47 domain a Serine_protease PF18405.1 EGD84839.1 - 0.24 10.5 2.6 1.7 7.7 0.2 3.0 2 1 0 3 3 3 0 Gammaproteobacterial serine protease IBR PF01485.21 EGD84840.1 - 3.4e-23 81.6 49.4 1.1e-12 48.0 6.4 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain UN_NPL4 PF11543.8 EGD84840.1 - 0.00045 20.7 0.0 0.00079 19.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_2 PF13639.6 EGD84840.1 - 0.00089 19.5 8.7 0.00089 19.5 8.7 3.9 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 EGD84840.1 - 0.0016 18.3 5.4 0.0016 18.3 5.4 4.4 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGD84840.1 - 0.0063 16.3 5.6 0.0063 16.3 5.6 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGD84840.1 - 0.012 15.5 9.6 0.012 15.5 9.6 3.6 3 1 0 3 3 3 0 zinc-RING finger domain W2 PF02020.18 EGD84842.1 - 1.8e-18 66.4 1.7 1.8e-18 66.4 1.7 3.5 4 0 0 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EGD84842.1 - 1.3e-11 43.7 12.5 1.6e-06 27.6 5.2 3.0 1 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EGD84842.1 - 5e-05 23.0 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 EGD84842.1 - 0.00015 21.5 7.7 0.0071 16.1 2.9 3.5 1 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EGD84842.1 - 0.0099 14.1 0.3 0.02 13.1 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EGD84842.1 - 0.085 11.8 0.1 0.2 10.6 0.1 1.5 1 1 0 1 1 1 0 L-fucokinase NOA36 PF06524.12 EGD84842.1 - 4.2 6.6 13.2 8.4 5.6 13.2 1.5 1 0 0 1 1 1 0 NOA36 protein Antifungal_pept PF11410.8 EGD84843.1 - 0.082 12.8 11.8 0.76 9.7 1.1 3.3 3 0 0 3 3 3 0 Antifungal peptide Tryp_inh PF17983.1 EGD84843.1 - 3.8 7.7 14.1 0.19 11.8 2.9 2.8 2 0 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 Response_reg PF00072.24 EGD84844.2 - 1.2e-17 64.1 0.0 8.5e-16 58.1 0.0 2.5 1 1 1 2 2 2 1 Response regulator receiver domain PIP5K PF01504.18 EGD84844.2 - 0.0029 16.9 0.0 0.52 9.5 0.0 2.5 2 1 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase SUIM_assoc PF16619.5 EGD84844.2 - 0.013 15.6 5.3 0.013 15.6 5.3 4.5 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 EGD84844.2 - 0.81 9.2 57.3 0.54 9.8 11.1 3.4 3 0 0 3 3 3 0 Spt20 family Spore_YhcN_YlaJ PF09580.10 EGD84844.2 - 1.6 8.8 13.1 6.2 6.9 5.1 2.6 2 1 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) TFIIA PF03153.13 EGD84844.2 - 4.9 7.0 63.0 1.1 9.2 12.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Redoxin PF08534.10 EGD84845.2 - 6.1e-24 84.4 0.1 1.8e-23 82.9 0.1 1.6 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGD84845.2 - 0.00048 20.0 0.0 0.00094 19.1 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family DUF2016 PF09436.10 EGD84845.2 - 0.15 11.9 0.0 4.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) BolA PF01722.18 EGD84846.2 - 1.4e-18 66.9 0.0 3.7e-18 65.6 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein NIF3 PF01784.18 EGD84847.2 - 2.5e-21 76.4 0.0 4.9e-21 75.5 0.0 1.5 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) COG6 PF06419.11 EGD84848.1 - 5.8e-208 692.1 0.2 6.5e-208 691.9 0.2 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Transcrip_act PF04949.13 EGD84848.1 - 0.0066 16.3 0.2 0.022 14.7 0.2 2.0 1 0 0 1 1 1 1 Transcriptional activator COG2 PF06148.11 EGD84848.1 - 0.24 11.5 1.9 14 5.8 0.1 3.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HSP9_HSP12 PF04119.12 EGD84849.1 - 1.8e-26 92.3 5.1 1.8e-26 92.3 5.1 1.8 2 0 0 2 2 2 1 Heat shock protein 9/12 ISG65-75 PF11727.8 EGD84849.1 - 0.061 12.6 1.6 0.074 12.3 1.6 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Chlorosome_CsmC PF11098.8 EGD84849.1 - 0.074 13.0 0.3 0.093 12.7 0.3 1.1 1 0 0 1 1 1 0 Chlorosome envelope protein C NYN PF01936.18 EGD84850.1 - 0.00021 21.8 0.1 0.0026 18.3 0.1 2.3 1 1 0 1 1 1 1 NYN domain Mog1 PF04603.12 EGD84851.1 - 2.1e-31 109.1 0.0 3.5e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DUF2576 PF10845.8 EGD84851.1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) ApeC PF16977.5 EGD84851.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of apextrin Glyco_hydro_72 PF03198.14 EGD84853.1 - 7.5e-132 439.3 9.5 9.4e-132 439.0 9.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EGD84853.1 - 7.8e-26 90.6 4.2 2.2e-25 89.1 4.2 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 EGD84853.1 - 9.5e-05 21.9 1.1 0.004 16.6 1.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_114 PF03537.13 EGD84853.1 - 0.0029 17.0 3.1 0.29 10.4 0.9 2.2 1 1 0 2 2 2 2 Glycoside-hydrolase family GH114 Glucan_synthase PF02364.15 EGD84854.1 - 0 1370.4 0.0 0 1369.8 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EGD84854.1 - 7.2e-43 146.0 0.2 7.2e-43 146.0 0.2 2.6 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.21 EGD84855.1 - 2e-34 119.4 0.0 2.5e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGD84855.1 - 0.039 12.5 0.0 0.34 9.4 0.0 2.0 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme RestrictionSfiI PF11487.8 EGD84855.1 - 0.097 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme SfiI Glyco_hydro_17 PF00332.18 EGD84856.1 - 1.7e-06 27.9 3.8 3.9e-06 26.7 0.4 2.3 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 DUF2013 PF09431.10 EGD84857.2 - 0.00061 20.0 0.2 0.00092 19.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) ABC_membrane PF00664.23 EGD84858.2 - 2.4e-38 132.4 10.0 3.1e-38 132.0 10.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGD84858.2 - 4.1e-34 118.0 0.0 7.3e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGD84858.2 - 5.2e-06 26.1 0.0 0.0011 18.5 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGD84858.2 - 8.6e-05 22.8 0.0 0.00029 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGD84858.2 - 0.00011 22.6 0.0 0.00028 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EGD84858.2 - 0.00042 20.2 0.1 0.008 16.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGD84858.2 - 0.0076 16.3 0.0 0.12 12.5 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EGD84858.2 - 0.012 15.4 0.4 0.025 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGD84858.2 - 0.012 15.3 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EGD84858.2 - 0.013 15.5 0.1 0.27 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGD84858.2 - 0.016 15.7 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGD84858.2 - 0.021 14.7 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 EGD84858.2 - 0.022 15.3 0.0 0.071 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGD84858.2 - 0.023 14.6 0.0 0.096 12.6 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 EGD84858.2 - 0.033 14.6 0.0 0.29 11.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rop-like PF05082.13 EGD84858.2 - 0.037 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Rop-like AAA_24 PF13479.6 EGD84858.2 - 0.039 13.7 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGD84858.2 - 0.04 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGD84858.2 - 0.043 14.1 0.0 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain GPAT_N PF14829.6 EGD84858.2 - 0.045 13.8 0.0 7.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal G-alpha PF00503.20 EGD84858.2 - 0.046 12.9 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit ATP-synt_ab PF00006.25 EGD84858.2 - 0.047 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 EGD84858.2 - 0.071 12.4 0.0 0.62 9.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Cytidylate_kin PF02224.18 EGD84858.2 - 0.078 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase AAA_10 PF12846.7 EGD84858.2 - 0.13 11.2 0.0 0.29 10.0 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AIM24 PF01987.17 EGD84859.1 - 1.6e-50 171.7 0.2 2.1e-50 171.3 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Peptidase_M43 PF05572.13 EGD84861.1 - 8.3e-16 58.3 1.0 1.6e-15 57.4 0.3 1.7 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EGD84861.1 - 0.00046 20.4 1.2 0.00087 19.5 1.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EGD84861.1 - 0.0026 18.3 0.1 0.0073 16.8 0.1 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 EGD84861.1 - 0.0076 16.4 0.6 0.02 15.0 0.1 1.9 2 0 0 2 2 2 1 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_4 PF13583.6 EGD84861.1 - 0.016 14.9 0.6 0.03 14.0 0.1 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EGD84861.1 - 0.061 13.2 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 EGD84861.1 - 0.51 10.2 4.0 0.21 11.4 1.6 1.7 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like HRI1 PF16815.5 EGD84862.1 - 2.3e-26 92.9 0.3 3.5e-26 92.3 0.3 1.4 1 1 0 1 1 1 1 Protein HRI1 Chromate_transp PF02417.15 EGD84863.1 - 1.2e-62 210.7 36.3 9.6e-33 113.5 14.7 2.3 2 0 0 2 2 2 2 Chromate transporter MFS_1 PF07690.16 EGD84865.1 - 8.4e-25 87.4 67.0 7.3e-20 71.2 34.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.23 EGD84866.1 - 9.6e-82 274.6 0.6 1.4e-81 274.0 0.6 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGD84866.1 - 7.9e-18 64.8 0.0 1.5e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 EGD84866.1 - 0.00012 21.8 0.0 0.032 14.1 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 EGD84866.1 - 0.028 14.7 0.0 0.34 11.2 0.0 2.4 1 1 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 EGD84866.1 - 0.063 13.9 0.1 7 7.3 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain Sec23_trunk PF04811.15 EGD84867.1 - 7.2e-72 241.9 0.0 1.4e-71 240.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGD84867.1 - 7.3e-22 77.1 0.0 2.8e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGD84867.1 - 7.5e-17 61.9 0.0 1.7e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGD84867.1 - 2.5e-16 59.5 3.7 4.5e-16 58.6 3.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGD84867.1 - 1.9e-06 27.7 0.0 3.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EGD84867.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pkinase PF00069.25 EGD84868.2 - 1.4e-67 227.9 0.0 1.6e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84868.2 - 8.8e-32 110.4 0.0 1.2e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGD84868.2 - 0.00052 19.4 0.2 0.00093 18.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGD84868.2 - 0.002 17.1 0.1 0.0032 16.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGD84868.2 - 0.01 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGD84868.2 - 0.029 14.3 0.2 0.057 13.3 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGD84868.2 - 0.081 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HEM4 PF02602.15 EGD84869.1 - 1.2e-35 122.9 0.0 4.1e-35 121.2 0.0 1.7 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.25 EGD84870.1 - 2.4e-05 23.8 0.0 2.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84870.1 - 0.015 14.6 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Beta_helix_2 PF18835.1 EGD84870.1 - 0.058 13.2 0.1 0.088 12.6 0.1 1.3 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase fn3 PF00041.21 EGD84871.2 - 1.3e-08 35.0 0.5 2.6e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Mem_trans PF03547.18 EGD84872.2 - 0.92 7.8 4.5 1.3 7.3 4.5 1.2 1 0 0 1 1 1 0 Membrane transport protein GMC_oxred_N PF00732.19 EGD84876.2 - 2.5e-43 148.6 0.0 3.1e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGD84876.2 - 3.2e-09 37.4 0.0 5.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Methyltransf_23 PF13489.6 EGD84877.1 - 2.2e-13 50.4 0.0 2.7e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD84877.1 - 1.6e-12 48.0 0.0 3.6e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD84877.1 - 1.9e-12 47.6 0.0 4.4e-12 46.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD84877.1 - 2.9e-12 46.6 0.0 3.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD84877.1 - 5.9e-12 46.1 0.0 1.2e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD84877.1 - 1.2e-07 31.3 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 EGD84877.1 - 0.046 13.2 0.0 0.062 12.8 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_15 PF09445.10 EGD84877.1 - 0.064 12.8 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DREV PF05219.12 EGD84877.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.6 EGD84877.1 - 0.14 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCI PF01399.27 EGD84878.1 - 1.4e-09 38.4 0.2 3.7e-09 37.0 0.1 1.9 2 0 0 2 2 2 1 PCI domain Rpn9_C PF18261.1 EGD84878.1 - 0.00011 21.7 0.1 0.00023 20.7 0.1 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Gaa1 PF04114.14 EGD84879.2 - 1.3e-130 436.8 0.1 1.5e-130 436.5 0.1 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF334 PF03904.13 EGD84879.2 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF334) RTA1 PF04479.13 EGD84881.1 - 4.8e-77 258.2 0.3 4.8e-77 258.2 0.3 1.5 1 1 1 2 2 2 1 RTA1 like protein PhrC_PhrF PF11131.8 EGD84881.1 - 3.6 7.2 5.8 14 5.3 1.3 2.8 2 0 0 2 2 2 0 Rap-phr extracellular signalling DUF4131 PF13567.6 EGD84881.1 - 8.7 6.0 6.6 11 5.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ytp1 PF10355.9 EGD84883.1 - 2e-116 388.1 8.4 2e-116 388.1 8.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EGD84883.1 - 1.3e-28 98.8 8.2 1.3e-28 98.8 8.2 3.2 4 0 0 4 4 4 2 Domain of unknown function (DUF2427) Rhomboid PF01694.22 EGD84884.1 - 4.3e-14 52.8 8.8 8e-14 51.9 8.8 1.3 1 0 0 1 1 1 1 Rhomboid family Abhydrolase_2 PF02230.16 EGD84885.1 - 1.3e-20 74.1 0.0 2.2e-15 57.1 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EGD84885.1 - 0.034 13.6 0.0 0.069 12.6 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family APH PF01636.23 EGD84886.2 - 6.3e-07 29.6 0.0 9.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4091 PF13320.6 EGD84886.2 - 0.016 15.3 0.2 0.031 14.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) DASH_Dam1 PF08653.10 EGD84888.2 - 4.2e-30 103.3 2.1 6.2e-30 102.8 2.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 Aminopep PF10023.9 EGD84888.2 - 0.049 13.0 0.4 0.062 12.7 0.4 1.1 1 0 0 1 1 1 0 Putative aminopeptidase CRAL_TRIO PF00650.20 EGD84889.2 - 3.7e-38 130.8 0.0 8.4e-38 129.6 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGD84889.2 - 3e-13 49.7 0.1 8.4e-13 48.3 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGD84889.2 - 1.2e-05 25.4 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HIT PF01230.23 EGD84890.2 - 1.9e-22 79.8 0.1 2.4e-22 79.5 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGD84890.2 - 2.4e-12 47.3 0.0 3.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGD84890.2 - 0.01 15.7 0.1 0.017 15.0 0.1 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Peptidase_M20 PF01546.28 EGD84891.1 - 6.9e-29 101.0 0.2 9.1e-29 100.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGD84891.1 - 3.1e-05 23.9 0.0 6.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGD84891.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 S10_plectin PF03501.15 EGD84892.2 - 7.3e-41 138.2 0.1 8.8e-41 137.9 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Sde2_N_Ubi PF13019.6 EGD84893.2 - 1.1e-67 227.0 0.2 1.1e-67 227.0 0.2 1.5 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Cep57_MT_bd PF06657.13 EGD84893.2 - 3 8.3 7.3 0.44 11.0 1.9 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 MMR_HSR1 PF01926.23 EGD84894.1 - 7e-05 22.9 0.3 0.2 11.7 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 EGD84895.1 - 1.3e-36 125.9 0.0 2.2e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EGD84895.1 - 1.9e-11 43.8 0.0 1.1e-07 31.7 0.0 3.4 3 0 0 3 3 3 2 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 EGD84895.1 - 1.1e-08 34.8 0.0 2.6e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EGD84895.1 - 5.9e-05 23.4 0.1 0.00042 20.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGD84895.1 - 0.00012 21.9 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGD84895.1 - 0.00013 22.2 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGD84895.1 - 0.00023 21.6 1.1 0.0056 17.1 0.1 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGD84895.1 - 0.0024 17.9 0.1 0.01 15.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGD84895.1 - 0.0037 16.5 0.0 0.0072 15.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EGD84895.1 - 0.0061 16.0 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGD84895.1 - 0.0085 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 EGD84895.1 - 0.032 13.4 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EGD84895.1 - 0.054 14.1 0.0 0.17 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EGD84895.1 - 0.068 12.6 0.0 2.2 7.6 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EGD84895.1 - 0.076 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGD84895.1 - 0.088 13.0 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGD84895.1 - 0.094 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGD84895.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 EGD84895.1 - 0.11 12.0 0.0 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ribosomal_S17 PF00366.20 EGD84896.1 - 1.6e-13 50.5 0.7 2.5e-13 49.9 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 A_deaminase PF00962.22 EGD84897.1 - 7e-21 74.9 0.0 1.3e-20 74.0 0.0 1.4 2 0 0 2 2 2 1 Adenosine/AMP deaminase ATG2_CAD PF13329.6 EGD84898.2 - 7.2e-46 155.7 0.1 1.7e-45 154.6 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EGD84898.2 - 4e-28 97.6 0.2 1.3e-27 96.0 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EGD84898.2 - 0.0021 17.8 0.1 0.0084 15.9 0.1 2.0 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal AMP-binding PF00501.28 EGD84902.1 - 3.6e-79 266.4 0.0 5.3e-79 265.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGD84902.1 - 2.4e-77 260.5 0.0 3.9e-77 259.9 0.0 1.2 1 0 0 1 1 1 1 Condensation domain ketoacyl-synt PF00109.26 EGD84902.1 - 5.2e-73 245.7 0.0 1.1e-72 244.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EGD84902.1 - 1e-60 205.5 0.0 1.6e-60 204.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EGD84902.1 - 2.5e-60 203.4 0.0 1.2e-59 201.3 0.0 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EGD84902.1 - 3.6e-57 194.3 0.0 6.6e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGD84902.1 - 3.5e-40 136.7 0.1 1.7e-39 134.5 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EGD84902.1 - 3e-36 124.9 0.0 5.7e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein KAsynt_C_assoc PF16197.5 EGD84902.1 - 1.4e-22 80.3 0.0 5.9e-22 78.2 0.0 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EGD84902.1 - 3.2e-20 72.2 0.2 4.2e-10 39.8 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 EGD84902.1 - 4.7e-18 66.5 0.0 2.2e-16 61.1 0.0 3.5 4 0 0 4 4 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGD84902.1 - 5.5e-18 65.2 0.0 4.9e-17 62.1 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EGD84902.1 - 4.6e-08 32.7 0.2 1.4e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD84902.1 - 2.3e-06 27.3 0.0 6.3e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EGD84902.1 - 0.00084 18.8 0.0 0.0024 17.3 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding_C PF13193.6 EGD84902.1 - 0.0021 19.0 0.0 0.0055 17.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1233 PF06806.12 EGD84902.1 - 0.089 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative excisionase (DUF1233) p450 PF00067.22 EGD84904.2 - 4.9e-13 48.6 0.0 8.1e-13 47.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF4327 PF14217.6 EGD84904.2 - 0.14 12.3 0.0 0.4 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) Asp PF00026.23 EGD84905.1 - 1.9e-12 47.2 0.3 2.6e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGD84905.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Thioesterase PF00975.20 EGD84906.1 - 1.4e-21 77.7 0.0 2.3e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 EGD84906.1 - 2.2e-07 30.8 0.0 2.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD84906.1 - 2.1e-05 25.3 0.0 2.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EGD84906.1 - 0.059 13.1 0.0 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGD84906.1 - 0.078 12.2 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 EGD84906.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 EGD84906.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAD_binding_3 PF01494.19 EGD84907.1 - 3.3e-32 112.1 0.1 4.3e-32 111.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EGD84907.1 - 2e-08 33.6 2.0 2.7e-05 23.2 0.1 2.7 2 1 1 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EGD84907.1 - 5.5e-06 25.8 0.2 0.012 14.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGD84907.1 - 0.00017 20.8 0.1 0.00031 19.9 0.1 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EGD84907.1 - 0.0017 18.5 0.4 0.0054 16.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGD84907.1 - 0.0068 16.9 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGD84907.1 - 0.039 13.2 0.1 0.091 12.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGD84907.1 - 0.37 10.7 1.5 1.9 8.5 0.1 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans PF04082.18 EGD84908.1 - 6.6e-09 35.2 2.8 1e-08 34.5 2.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD84908.1 - 3.6e-06 27.0 8.0 6.6e-06 26.1 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF885 PF05960.11 EGD84908.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Ran_BP1 PF00638.18 EGD84910.1 - 5.3e-13 49.3 0.0 1.1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 EGD84910.1 - 0.0016 19.2 46.2 0.0038 18.0 22.2 11.2 3 3 9 12 12 12 6 Nucleoporin FG repeat region NUP50 PF08911.11 EGD84910.1 - 0.0066 17.1 2.4 0.0066 17.1 2.4 6.1 3 1 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) SCP2 PF02036.17 EGD84911.2 - 1.2e-24 86.7 0.1 1.5e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EGD84911.2 - 4.5e-05 23.7 0.0 5.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 EGD84911.2 - 0.0039 17.6 0.0 0.0053 17.1 0.0 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain F-box-like PF12937.7 EGD84912.1 - 0.0015 18.4 0.1 0.41 10.6 0.0 2.7 2 0 0 2 2 2 2 F-box-like SNF2_N PF00176.23 EGD84913.2 - 7.2e-61 205.8 0.3 1.6e-60 204.7 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGD84913.2 - 2.3e-14 53.6 0.0 5.8e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EGD84913.2 - 3.2e-08 33.3 1.8 3.2e-08 33.3 1.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGD84913.2 - 3.5e-08 33.2 3.0 7.6e-08 32.1 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGD84913.2 - 4e-06 26.6 3.9 8.5e-06 25.6 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EGD84913.2 - 6.6e-06 26.2 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 EGD84913.2 - 4e-05 23.9 4.1 9.8e-05 22.6 4.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGD84913.2 - 6.7e-05 22.8 3.8 0.00015 21.6 3.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGD84913.2 - 7.8e-05 22.6 2.4 0.00019 21.4 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGD84913.2 - 0.00085 19.1 4.2 0.0033 17.2 4.2 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGD84913.2 - 0.0017 18.1 3.6 0.0042 16.8 3.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EGD84913.2 - 0.017 15.3 5.6 0.037 14.2 5.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DZR PF12773.7 EGD84913.2 - 0.063 13.3 3.1 0.16 12.0 3.1 1.7 1 1 0 1 1 1 0 Double zinc ribbon CCDC50_N PF15295.6 EGD84913.2 - 0.98 9.6 7.7 2.3 8.4 7.7 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus DUF1644 PF07800.12 EGD84913.2 - 2.7 8.0 5.0 27 4.8 2.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) Ras PF00071.22 EGD84914.1 - 2e-49 167.3 0.0 2.5e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD84914.1 - 2.4e-29 102.0 0.0 6.1e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD84914.1 - 6.3e-11 42.0 0.0 9.5e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 EGD84914.1 - 0.00026 21.3 0.1 0.0015 18.9 0.1 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 EGD84914.1 - 0.00095 19.2 0.0 0.002 18.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGD84914.1 - 0.0012 18.3 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGD84914.1 - 0.0052 16.0 1.2 1.6 7.8 0.1 2.8 2 1 1 3 3 3 2 G-protein alpha subunit Pox_A32 PF04665.12 EGD84914.1 - 0.021 14.3 0.1 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 EGD84914.1 - 0.032 14.1 0.1 7.5 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EGD84914.1 - 0.035 13.6 0.1 0.059 12.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGD84914.1 - 0.062 13.0 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGD84914.1 - 0.086 12.8 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EGD84914.1 - 0.093 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EGD84914.1 - 0.11 12.6 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EGD84914.1 - 0.16 11.3 0.3 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 Septin Nas2_N PF18265.1 EGD84915.1 - 1.1e-27 95.7 0.1 1.9e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EGD84915.1 - 1e-07 31.7 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EGD84915.1 - 1.1e-06 28.9 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGD84915.1 - 1.5e-05 25.3 0.1 2.8e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EGD84915.1 - 1.7e-05 25.1 0.0 3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain SBDS PF01172.18 EGD84917.1 - 1.4e-25 89.1 0.1 1.7e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein NAD_binding_6 PF08030.12 EGD84918.1 - 5.8e-23 81.7 0.0 1e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGD84918.1 - 1.2e-22 80.1 0.0 2.6e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EGD84918.1 - 7.1e-21 74.6 9.4 1.5e-20 73.6 9.4 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 EGD84918.1 - 0.046 14.1 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGD84918.1 - 0.048 14.3 0.0 5.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain 7TMR-DISM_7TM PF07695.11 EGD84920.2 - 0.6 10.0 8.5 1.7 8.5 8.5 1.6 1 1 0 1 1 1 0 7TM diverse intracellular signalling UDG PF03167.19 EGD84921.1 - 3.5e-19 69.3 0.0 7e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily NRDE-2 PF08424.10 EGD84922.1 - 2.7e-94 315.9 0.4 4.4e-93 311.9 0.0 2.7 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EGD84922.1 - 0.0061 17.3 6.6 8.4 7.5 0.0 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGD84922.1 - 0.072 13.6 0.3 15 6.2 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGD84922.1 - 0.4 10.7 2.1 5.1 7.1 0.3 3.2 2 1 0 3 3 3 0 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 EGD84922.1 - 2.7 8.6 5.9 0.38 11.2 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CN_hydrolase PF00795.22 EGD84924.1 - 3.2e-30 105.3 0.0 4.4e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MMS1_N PF10433.9 EGD84925.1 - 1e-158 529.0 0.0 1.4e-158 528.5 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGD84925.1 - 1.7e-102 343.1 0.0 7e-101 337.7 0.0 2.8 3 0 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 EGD84925.1 - 0.045 14.1 0.0 2.4 8.5 0.0 3.6 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ubiquitin PF00240.23 EGD84926.1 - 4e-19 68.1 0.0 6.4e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EGD84926.1 - 2.4e-07 30.5 0.1 2.4e-07 30.5 0.1 1.8 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 EGD84926.1 - 2.2e-05 24.2 0.0 3.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGD84926.1 - 0.00015 22.3 0.3 0.00047 20.7 0.0 1.9 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGD84926.1 - 0.00066 19.8 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 EGD84926.1 - 0.014 15.3 19.0 0.026 14.5 1.3 3.0 3 0 0 3 3 3 0 STI1 domain HOIP-UBA PF16678.5 EGD84926.1 - 0.042 13.8 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair GerD PF17898.1 EGD84926.1 - 0.18 11.8 4.0 0.47 10.4 3.3 2.0 1 1 0 1 1 1 0 Spore germination GerD central core domain SPX PF03105.19 EGD84926.1 - 4.7 7.0 19.2 29 4.4 19.2 1.9 1 1 0 1 1 1 0 SPX domain EMP70 PF02990.16 EGD84927.1 - 2.5e-186 620.4 0.0 3.3e-186 620.0 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DER1 PF04511.15 EGD84928.1 - 2.2e-47 161.5 6.3 2.5e-47 161.3 6.3 1.0 1 0 0 1 1 1 1 Der1-like family Serpentine_r_xa PF03383.15 EGD84928.1 - 0.068 13.1 1.8 0.12 12.4 1.8 1.4 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa Histone PF00125.24 EGD84929.1 - 1.5e-41 141.8 0.2 2e-41 141.4 0.2 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGD84929.1 - 5.8e-05 23.2 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGD84929.1 - 0.00044 20.6 0.0 0.00066 20.0 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGD84929.1 - 0.0063 16.8 0.3 0.012 15.8 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGD84929.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Cohesin_load PF10345.9 EGD84930.2 - 8.7e-58 196.2 1.5 1.1e-57 195.9 1.5 1.0 1 0 0 1 1 1 1 Cohesin loading factor Lactamase_B_4 PF13691.6 EGD84930.2 - 0.01 15.5 0.0 0.031 14.0 0.0 1.7 2 0 0 2 2 2 0 tRNase Z endonuclease EAP30 PF04157.16 EGD84930.2 - 0.024 13.9 0.1 0.07 12.4 0.0 2.1 2 1 0 2 2 2 0 EAP30/Vps36 family TPR_4 PF07721.14 EGD84930.2 - 0.087 13.5 6.5 5.2 8.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGD84930.2 - 0.11 12.7 5.4 1.1 9.6 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF883 PF05957.13 EGD84930.2 - 1.5 9.5 5.0 31 5.3 0.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) TLP1_add_C PF18313.1 EGD84932.1 - 9.5e-25 86.4 0.2 2.7e-24 84.9 0.0 1.9 2 0 0 2 2 2 1 Thiolase-like protein type 1 additional C-terminal domain PAC3 PF10178.9 EGD84933.1 - 6.2e-05 23.1 0.0 0.00013 22.1 0.0 1.5 1 1 0 1 1 1 1 Proteasome assembly chaperone 3 HA2 PF04408.23 EGD84934.1 - 1.4e-27 96.1 0.1 1.4e-27 96.1 0.1 2.8 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGD84934.1 - 5e-12 46.0 0.0 1.3e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGD84934.1 - 6.2e-12 45.9 0.0 2.1e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGD84934.1 - 4.3e-10 39.6 0.0 1.5e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGD84934.1 - 0.0021 18.1 1.2 1.6 8.7 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGD84934.1 - 0.0023 18.3 0.0 0.0044 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGD84934.1 - 0.0086 16.4 0.6 0.027 14.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGD84934.1 - 0.011 16.3 0.0 0.011 16.3 0.0 3.8 3 1 0 3 3 2 0 AAA domain AAA_30 PF13604.6 EGD84934.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGD84934.1 - 0.068 12.2 0.1 0.21 10.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 EGD84934.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EGD84934.1 - 0.09 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family cwf21 PF08312.12 EGD84935.1 - 2.2e-14 53.3 23.9 1.3e-13 50.9 23.9 2.3 1 1 0 1 1 1 1 cwf21 domain Peptidase_S64 PF08192.11 EGD84935.1 - 0.89 8.0 4.2 0.2 10.1 1.3 1.3 2 0 0 2 2 2 0 Peptidase family S64 Atg14 PF10186.9 EGD84935.1 - 3 6.8 9.3 5.2 6.1 9.4 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RRN3 PF05327.11 EGD84935.1 - 3.6 6.0 5.0 4.2 5.8 5.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Phosphodiest PF01663.22 EGD84936.1 - 1.1e-15 58.2 0.5 1.9e-15 57.3 0.5 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EGD84936.1 - 4.8e-05 22.8 0.3 0.0001 21.8 0.3 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EGD84936.1 - 0.00031 20.2 0.1 0.00054 19.5 0.1 1.4 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 EGD84936.1 - 0.057 13.5 0.7 13 5.8 0.1 2.4 2 0 0 2 2 2 0 PglZ domain DUF5326 PF17260.2 EGD84937.1 - 0.05 13.7 0.1 0.073 13.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5326) PUF PF00806.19 EGD84940.2 - 2.7e-57 187.3 7.0 1.9e-07 30.4 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Cse1 PF08506.10 EGD84942.2 - 7.9e-158 525.1 3.3 1.1e-157 524.6 3.3 1.2 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 EGD84942.2 - 2.7e-53 181.1 0.1 8.4e-53 179.4 0.1 1.9 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 EGD84942.2 - 7e-17 61.1 0.3 3.1e-16 59.0 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGD84942.2 - 0.026 14.6 0.1 1.2 9.2 0.0 3.4 3 0 0 3 3 3 0 Exportin 1-like protein V-ATPase_H_N PF03224.14 EGD84942.2 - 0.046 13.0 0.7 0.13 11.5 0.1 2.0 3 0 0 3 3 3 0 V-ATPase subunit H RF-1 PF00472.20 EGD84943.1 - 7.2e-25 87.2 6.2 1.1e-24 86.6 6.2 1.2 1 0 0 1 1 1 1 RF-1 domain DUF134 PF02001.16 EGD84943.1 - 0.046 14.3 2.2 0.17 12.4 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF134 XRN_M PF17846.1 EGD84943.1 - 0.62 8.9 2.9 0.76 8.7 2.9 1.0 1 0 0 1 1 1 0 Xrn1 helical domain SPT_ssu-like PF11779.8 EGD84944.1 - 1.4e-23 82.2 5.2 1.9e-23 81.8 5.2 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Ldh_2 PF02615.14 EGD84946.1 - 2.3e-126 421.5 0.1 2.6e-126 421.3 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase PAP2 PF01569.21 EGD84947.1 - 5.8e-15 55.3 4.3 2.7e-14 53.1 4.3 2.0 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 EGD84947.1 - 0.0094 16.1 0.0 2.4 8.3 0.0 2.3 2 0 0 2 2 2 2 Divergent PAP2 family IBR PF01485.21 EGD84948.1 - 3.1e-18 65.7 40.4 1.1e-15 57.6 2.8 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 EGD84948.1 - 3.4e-17 62.8 0.0 9.5e-17 61.3 0.0 1.8 1 1 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 EGD84948.1 - 0.023 15.0 9.0 0.023 15.0 9.0 4.1 3 1 1 4 4 4 0 Ring finger domain Wzy_C PF04932.15 EGD84949.1 - 0.0066 16.1 0.0 0.018 14.7 0.1 1.6 2 0 0 2 2 2 1 O-Antigen ligase rRNA_proc-arch PF13234.6 EGD84950.2 - 0.037 13.9 0.2 0.069 13.1 0.2 1.4 1 0 0 1 1 1 0 rRNA-processing arch domain RabGAP-TBC PF00566.18 EGD84952.2 - 3.8e-38 131.3 5.1 8.1e-38 130.2 5.1 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain GAS2 PF02187.17 EGD84953.1 - 4.6e-06 26.6 0.3 1e-05 25.5 0.3 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hus1 PF04005.12 EGD84954.1 - 4.2e-108 360.9 0.0 4.7e-108 360.7 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.7 EGD84955.1 - 3.2e-111 371.8 0.3 4.4e-111 371.4 0.3 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.7 EGD84955.1 - 3.8e-60 204.0 21.6 3.8e-60 204.0 21.6 4.8 4 1 0 4 4 4 2 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.7 EGD84955.1 - 8e-33 113.5 0.1 1.9e-32 112.3 0.1 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region PhoLip_ATPase_C PF16212.5 EGD84956.2 - 8.4e-47 160.0 7.3 1.2e-46 159.6 7.3 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EGD84956.2 - 8.5e-14 52.3 0.2 2.4e-08 34.5 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGD84956.2 - 5.2e-08 32.9 0.0 2.1e-06 27.7 0.0 2.5 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGD84956.2 - 0.0033 17.2 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HIGH_NTase1_ass PF16581.5 EGD84956.2 - 0.012 15.6 0.1 0.039 14.0 0.0 1.8 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region LacAB_rpiB PF02502.18 EGD84956.2 - 0.13 12.3 0.4 3.8 7.5 0.1 2.7 2 0 0 2 2 2 0 Ribose/Galactose Isomerase Mso1_Sec1_bdg PF14475.6 EGD84957.1 - 4.6e-13 48.5 0.0 8.2e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 EGD84958.1 - 1.6e-38 132.0 0.6 2.6e-38 131.3 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 EGD84958.1 - 2.5e-30 105.0 14.0 2.5e-30 105.0 14.0 2.3 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EGD84958.1 - 4.2e-06 26.4 15.0 5.2e-06 26.1 15.0 1.1 1 0 0 1 1 1 1 BUD22 Ribosomal_L24e PF01246.20 EGD84958.1 - 0.0086 16.3 0.3 0.022 15.0 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e PYC_OADA PF02436.18 EGD84958.1 - 0.026 14.3 1.3 0.043 13.6 0.9 1.5 1 1 0 1 1 1 0 Conserved carboxylase domain TFIIF_alpha PF05793.12 EGD84958.1 - 0.54 8.8 24.6 0.63 8.6 24.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 EGD84958.1 - 0.99 7.5 25.1 1.3 7.2 25.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGD84958.1 - 1.1 7.4 20.8 0.36 9.1 16.4 1.9 2 0 0 2 2 2 0 CDC45-like protein zf-C2H2_2 PF12756.7 EGD84959.2 - 0.07 13.5 3.2 0.55 10.6 0.3 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.12 EGD84959.2 - 0.32 11.2 8.4 2.1 8.6 0.6 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_4 PF13894.6 EGD84959.2 - 0.51 11.3 16.7 0.59 11.1 2.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGD84959.2 - 3 8.5 11.2 0.72 10.4 1.9 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type ECH_1 PF00378.20 EGD84960.1 - 2.7e-24 85.8 0.0 3.4e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGD84960.1 - 2.1e-17 63.7 0.1 2.3e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase D123 PF07065.14 EGD84961.1 - 1.3e-110 369.4 0.1 1.6e-110 369.1 0.1 1.1 1 0 0 1 1 1 1 D123 SURF6 PF04935.12 EGD84962.2 - 0.024 14.4 1.7 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Surfeit locus protein 6 Musclin PF11037.8 EGD84962.2 - 0.024 14.5 0.3 2.7 7.9 0.1 2.3 1 1 1 2 2 2 0 Insulin-resistance promoting peptide in skeletal muscle DUF1640 PF07798.11 EGD84963.1 - 4.9e-35 121.1 8.5 6.8e-35 120.7 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HIP1_clath_bdg PF16515.5 EGD84963.1 - 0.0013 19.3 2.1 0.0036 17.9 2.1 1.7 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1387 PF07139.11 EGD84963.1 - 0.0071 16.1 13.8 0.028 14.2 1.1 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1387) Adhesin_E PF16747.5 EGD84963.1 - 0.12 12.4 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Surface-adhesin protein E Baculo_PEP_C PF04513.12 EGD84963.1 - 0.87 9.6 5.9 1.5 8.8 5.9 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ALMT PF11744.8 EGD84963.1 - 2 7.1 10.6 0.024 13.5 1.6 2.1 1 1 1 2 2 2 0 Aluminium activated malate transporter HEAT_2 PF13646.6 EGD84964.1 - 6e-08 33.0 0.0 0.25 11.8 0.0 5.6 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EGD84964.1 - 4.5e-05 23.3 6.7 3.2 8.2 0.0 7.9 8 0 0 8 8 8 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EGD84964.1 - 0.00047 20.7 0.1 0.11 13.1 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 EGD84964.1 - 0.0053 16.8 0.2 3.6 7.8 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EGD84964.1 - 0.0071 14.9 1.4 6.6 5.2 0.0 3.9 4 0 0 4 4 4 1 Adaptin N terminal region HEAT_EZ PF13513.6 EGD84964.1 - 0.023 15.2 10.8 37 5.0 0.0 6.7 7 0 0 7 7 7 0 HEAT-like repeat RTP1_C1 PF10363.9 EGD84964.1 - 0.061 13.5 0.0 51 4.1 0.0 4.3 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 EGD84964.1 - 0.068 12.4 2.7 1.1 8.4 0.1 3.3 3 0 0 3 3 3 0 V-ATPase subunit H Cnd1 PF12717.7 EGD84964.1 - 0.34 10.9 3.4 5.1 7.1 0.0 4.1 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGD84964.1 - 2.1 7.9 8.0 8.4 5.9 0.1 4.5 5 0 0 5 5 5 0 CLASP N terminal Transcrip_reg PF01709.20 EGD84965.2 - 2.2e-48 164.8 0.2 2.5e-48 164.6 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator NapD PF03927.13 EGD84965.2 - 0.62 10.1 3.0 2.2 8.4 0.2 2.6 3 0 0 3 3 3 0 NapD protein CENP-I PF07778.11 EGD84966.1 - 1.6e-47 162.4 2.0 1e-46 159.7 2.0 1.9 1 1 0 1 1 1 1 Mis6 Rsa3 PF14615.6 EGD84966.1 - 0.07 12.7 0.2 0.19 11.3 0.2 1.7 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Sedlin_N PF04628.13 EGD84966.1 - 0.072 13.2 0.0 0.94 9.6 0.0 2.4 2 0 0 2 2 2 0 Sedlin, N-terminal conserved region Glyco_transf_90 PF05686.12 EGD84966.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 90 DUF4360 PF14273.6 EGD84967.1 - 1.3e-70 236.9 2.8 1.6e-70 236.6 2.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CLPTM1 PF05602.12 EGD84968.2 - 3.7e-149 497.4 0.7 4.6e-149 497.1 0.7 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) MtN3_slv PF03083.16 EGD84968.2 - 0.22 11.6 3.0 0.12 12.4 0.3 2.0 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange SyrA PF11089.8 EGD84968.2 - 0.51 10.4 2.4 16 5.6 0.6 2.6 2 0 0 2 2 2 0 Exopolysaccharide production repressor adh_short PF00106.25 EGD84969.1 - 4.2e-20 72.0 0.0 1.1e-19 70.6 0.0 1.7 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD84969.1 - 7.7e-15 55.1 0.0 1.2e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Longin PF13774.6 EGD84971.1 - 1.3e-25 89.2 0.6 2.2e-25 88.5 0.6 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EGD84971.1 - 2.9e-15 55.8 0.7 1e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Synaptobrevin SLM4 PF16818.5 EGD84971.1 - 0.012 15.6 1.3 0.17 11.8 0.1 2.2 1 1 1 2 2 2 0 Protein SLM4 SCVP PF17619.2 EGD84971.1 - 0.071 14.0 0.6 1.3 10.0 0.0 2.2 2 0 0 2 2 2 0 Secreted clade V proteins DUF1664 PF07889.12 EGD84971.1 - 0.16 12.1 5.7 0.28 11.2 0.6 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SIMPL PF04402.14 EGD84971.1 - 0.35 11.3 3.4 1.1 9.7 3.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF541) YgaB PF14182.6 EGD84971.1 - 0.53 10.7 2.9 0.84 10.1 0.2 2.4 2 1 1 3 3 3 0 YgaB-like protein EMP24_GP25L PF01105.24 EGD84971.1 - 1.9 8.4 6.1 1.6 8.7 0.6 2.1 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Elong_Iki1 PF10483.9 EGD84972.1 - 2e-101 339.4 0.0 2.3e-101 339.2 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 SNRNP27 PF08648.12 EGD84973.1 - 3e-26 91.2 1.9 7.1e-26 90.0 1.9 1.7 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DAO PF01266.24 EGD84974.2 - 5e-42 144.7 0.1 5.5e-42 144.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGD84974.2 - 0.081 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_63 PF03200.16 EGD84975.1 - 3.1e-174 580.3 2.3 3.1e-174 580.3 2.3 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EGD84975.1 - 3.7e-89 298.7 0.1 3.2e-88 295.6 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EGD84975.1 - 0.0039 16.1 0.8 0.0083 15.0 0.8 1.5 1 1 0 1 1 1 1 Trehalase MMtag PF10159.9 EGD84976.1 - 2.6e-33 114.1 3.4 2.6e-33 114.1 3.4 2.6 2 1 0 2 2 2 1 Multiple myeloma tumor-associated PAP1 PF08601.10 EGD84976.1 - 0.69 9.6 4.9 1.1 9.0 4.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 CRT10 PF08728.10 EGD84977.2 - 0.00028 19.2 0.0 0.00028 19.2 0.0 1.5 2 0 0 2 2 2 1 CRT10 TFIIF_alpha PF05793.12 EGD84977.2 - 3.3 6.2 19.9 4.7 5.7 19.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) E7 PF00527.18 EGD84977.2 - 8.1 6.7 5.9 23 5.3 5.9 1.8 1 0 0 1 1 1 0 E7 protein, Early protein BUD22 PF09073.10 EGD84977.2 - 9.7 5.4 19.7 14 4.9 19.7 1.1 1 0 0 1 1 1 0 BUD22 DUF3402 PF11882.8 EGD84978.2 - 5.4e-98 329.1 0.0 6.6e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) Catalase PF00199.19 EGD84980.1 - 2.4e-173 576.7 0.5 2.9e-173 576.3 0.5 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGD84980.1 - 1.7e-16 60.1 0.0 3.2e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 EGD84980.1 - 2.3e-08 33.8 0.5 1.4e-07 31.3 0.1 2.4 3 0 0 3 3 3 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EGD84980.1 - 0.00061 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family EF-hand_11 PF08976.11 EGD84980.1 - 0.028 15.3 0.0 0.098 13.5 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain YIF1 PF03878.15 EGD84981.2 - 2.3e-82 276.1 1.6 2.9e-82 275.8 1.6 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EGD84981.2 - 0.00055 19.7 7.1 0.00085 19.1 7.1 1.2 1 0 0 1 1 1 1 Yip1 domain SRP-alpha_N PF04086.13 EGD84982.1 - 3.3e-76 257.0 0.0 4.5e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EGD84982.1 - 7.8e-50 169.2 0.0 1.3e-49 168.5 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EGD84982.1 - 3e-10 40.2 0.0 8.4e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EGD84982.1 - 1.6e-05 24.1 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGD84982.1 - 0.00088 19.0 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGD84982.1 - 0.0048 17.3 0.0 0.021 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EGD84982.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EGD84982.1 - 0.01 15.9 0.0 0.041 14.0 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 EGD84982.1 - 0.03 14.4 0.1 0.15 12.2 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Fer4_NifH PF00142.18 EGD84982.1 - 0.053 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_17 PF13207.6 EGD84982.1 - 0.067 13.6 0.1 0.31 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_31 PF13614.6 EGD84982.1 - 0.087 12.7 0.0 0.19 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.16 EGD84983.1 - 1.2e-34 119.8 28.2 7.9e-22 77.6 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD84983.1 - 3.6e-11 42.6 14.0 1.9e-10 40.2 6.6 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EGD84983.1 - 5e-06 26.0 3.4 5e-06 26.0 3.4 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EGD84983.1 - 1.7e-05 23.9 10.9 0.0005 19.0 0.4 3.4 2 2 1 3 3 3 2 MFS_1 like family MFS_2 PF13347.6 EGD84983.1 - 0.00014 20.6 13.1 0.14 10.7 2.8 3.7 2 2 2 4 4 4 3 MFS/sugar transport protein Folate_carrier PF01770.18 EGD84983.1 - 0.00056 18.8 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 Reduced folate carrier LacY_symp PF01306.19 EGD84983.1 - 0.0078 15.0 3.7 0.29 9.8 0.1 2.3 2 1 0 2 2 2 2 LacY proton/sugar symporter Ribosomal_L14e PF01929.17 EGD84984.1 - 9.4e-32 109.4 2.2 1.3e-31 108.9 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EGD84984.1 - 1.1e-06 28.3 0.1 1.9e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 KOW motif NAC PF01849.18 EGD84985.1 - 3.2e-22 78.2 0.0 1.1e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 NAC domain Cytomega_UL84 PF06284.11 EGD84985.1 - 0.19 10.2 0.6 0.22 9.9 0.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Shadoo PF14999.6 EGD84985.1 - 0.2 11.8 3.2 0.36 10.9 3.2 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PGA2 PF07543.12 EGD84985.1 - 6.9 6.6 12.0 3.2 7.7 7.8 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 Myc_N PF01056.18 EGD84985.1 - 8 6.2 9.1 1.8 8.4 5.4 1.6 1 1 0 2 2 2 0 Myc amino-terminal region Mt_ATP-synt_D PF05873.12 EGD84986.1 - 7.2e-24 84.4 2.4 8.8e-24 84.1 2.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) E3_UbLigase_R4 PF13764.6 EGD84986.1 - 0.014 13.6 0.5 0.015 13.5 0.5 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 T2SSM_b PF10741.9 EGD84986.1 - 0.021 14.6 0.3 0.088 12.6 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DUF948 PF06103.11 EGD84986.1 - 0.12 12.7 1.5 0.88 9.9 0.4 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) F-box-like_2 PF13013.6 EGD84988.2 - 0.033 14.1 2.2 0.56 10.2 0.2 2.9 3 0 0 3 3 3 0 F-box-like domain Pkinase PF00069.25 EGD84989.1 - 1.1e-33 116.8 0.0 1.6e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD84989.1 - 2.9e-22 79.2 0.0 4.4e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGD84989.1 - 0.0024 17.8 0.0 0.0077 16.2 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGD84989.1 - 0.019 14.3 0.1 0.042 13.2 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGD84989.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EGD84989.1 - 0.052 12.3 0.1 0.1 11.3 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase DUF2992 PF11208.8 EGD84990.1 - 0.091 13.0 6.5 0.044 14.0 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Aldedh PF00171.22 EGD84992.1 - 8.8e-122 406.9 0.0 1.1e-121 406.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HhH-GPD PF00730.25 EGD84993.1 - 2.4e-07 31.2 0.0 4.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Pribosyltran PF00156.27 EGD84994.2 - 2.2e-07 30.5 0.6 4.5e-07 29.5 0.1 1.7 2 1 0 2 2 2 1 Phosphoribosyl transferase domain GATase_6 PF13522.6 EGD84995.2 - 0.00024 21.3 0.0 0.00037 20.7 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase domain DNA_methylase PF00145.17 EGD84996.2 - 1.5e-41 142.9 0.0 2.4e-31 109.3 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase MmgE_PrpD PF03972.14 EGD84997.1 - 1.2e-146 488.8 0.0 1.3e-146 488.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family AMP-binding PF00501.28 EGD84998.1 - 3.8e-66 223.4 0.0 4.7e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD84998.1 - 7.4e-05 23.6 0.0 0.0002 22.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1661 PF07877.11 EGD84998.1 - 0.13 11.9 0.4 0.31 10.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) ICL PF00463.21 EGD84999.2 - 6.2e-196 652.0 0.1 7.5e-196 651.7 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EGD84999.2 - 3.1e-10 39.9 0.0 2e-09 37.3 0.0 1.9 1 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Citrate_synt PF00285.21 EGD85000.2 - 8.4e-98 327.8 0.0 1.2e-97 327.3 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Glyco_hydro_92 PF07971.12 EGD85001.2 - 5.3e-128 427.8 0.1 6.3e-128 427.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 ABC_tran PF00005.27 EGD85002.1 - 8.3e-44 149.4 0.1 2.6e-24 86.3 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGD85002.1 - 1.9e-16 60.8 0.4 3.3e-05 23.9 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGD85002.1 - 5.7e-11 42.3 1.0 0.0017 17.9 0.0 4.3 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EGD85002.1 - 2.4e-08 33.8 0.1 5e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 EGD85002.1 - 2.8e-08 33.8 0.0 0.013 15.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGD85002.1 - 8.3e-07 29.1 0.1 0.027 14.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EGD85002.1 - 1.7e-06 28.7 3.0 0.0062 17.1 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 EGD85002.1 - 1.7e-05 24.4 2.5 0.11 12.3 1.2 2.9 2 1 1 3 3 3 2 P-loop containing region of AAA domain DUF87 PF01935.17 EGD85002.1 - 0.00012 22.2 0.2 0.064 13.4 0.1 3.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_28 PF13521.6 EGD85002.1 - 0.00036 20.8 0.1 0.018 15.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 EGD85002.1 - 0.0005 20.3 0.0 0.96 9.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGD85002.1 - 0.00058 19.8 0.9 0.26 11.2 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 EGD85002.1 - 0.00064 19.5 0.0 0.88 9.2 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EGD85002.1 - 0.00097 19.7 0.3 8.7 6.9 0.0 3.8 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EGD85002.1 - 0.0016 18.8 0.1 1.8 9.0 0.0 2.8 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.6 EGD85002.1 - 0.0094 16.2 0.0 11 6.4 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EGD85002.1 - 0.012 15.8 0.1 8.8 6.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EGD85002.1 - 0.018 14.8 0.5 2 8.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EGD85002.1 - 0.02 13.9 0.4 4 6.3 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 EGD85002.1 - 0.024 13.8 0.3 0.93 8.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 EGD85002.1 - 0.025 14.3 3.0 1.2 8.8 0.2 3.3 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 EGD85002.1 - 0.027 14.2 0.1 0.92 9.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 EGD85002.1 - 0.027 14.1 0.1 5 6.7 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 EGD85002.1 - 0.036 14.5 0.1 3 8.3 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 EGD85002.1 - 0.053 12.2 0.0 4.7 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGD85002.1 - 0.055 13.6 0.0 12 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain SR-25 PF10500.9 EGD85002.1 - 0.058 13.0 0.5 0.11 12.1 0.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ALF PF03752.13 EGD85002.1 - 0.064 13.2 2.7 0.26 11.3 0.6 2.6 2 0 0 2 2 2 0 Short repeats of unknown function Ploopntkinase3 PF18751.1 EGD85002.1 - 0.075 12.9 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 HEAT PF02985.22 EGD85002.1 - 0.093 13.0 0.4 1.1e+02 3.5 0.0 4.4 5 0 0 5 5 4 0 HEAT repeat MukB PF04310.12 EGD85002.1 - 0.098 12.4 0.3 2 8.2 0.1 2.3 2 0 0 2 2 2 0 MukB N-terminal DUF3584 PF12128.8 EGD85002.1 - 0.11 10.0 2.9 1.2 6.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_16 PF13191.6 EGD85002.1 - 0.14 12.5 0.1 41 4.5 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain DUF815 PF05673.13 EGD85002.1 - 0.18 10.9 0.5 6.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EGD85002.1 - 0.54 10.1 3.8 11 5.9 0.0 3.5 4 0 0 4 4 3 0 NTPase GST_N_2 PF13409.6 EGD85003.2 - 4.4e-11 42.9 0.0 9.8e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGD85003.2 - 2.1e-09 37.7 0.0 4.5e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGD85003.2 - 9.3e-06 25.6 0.1 7.7e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGD85003.2 - 0.0004 20.6 0.0 0.00079 19.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGD85003.2 - 0.0052 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AA_permease_2 PF13520.6 EGD85004.2 - 3.4e-51 174.4 48.3 4.1e-51 174.1 48.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD85004.2 - 1.4e-18 66.8 35.9 2e-18 66.3 35.9 1.1 1 0 0 1 1 1 1 Amino acid permease LapA_dom PF06305.11 EGD85004.2 - 2.1 8.2 5.3 0.51 10.2 0.1 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Serpin PF00079.20 EGD85005.1 - 4.2e-53 181.0 0.0 5.3e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Glyco_hydro_3_C PF01915.22 EGD85006.1 - 8.2e-44 150.0 0.0 1.4e-43 149.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGD85006.1 - 7.4e-36 124.1 0.0 1.1e-35 123.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGD85006.1 - 4.6e-22 77.9 0.1 1e-21 76.8 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain FMO-like PF00743.19 EGD85007.1 - 9.8e-16 57.3 0.0 8.2e-12 44.3 0.1 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EGD85007.1 - 4.5e-11 42.8 0.0 2.4e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGD85007.1 - 4.8e-08 32.6 0.0 0.0024 17.2 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGD85007.1 - 0.00017 20.8 0.0 0.12 11.5 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EGD85007.1 - 0.00018 21.2 0.1 0.028 14.0 0.1 3.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGD85007.1 - 0.0011 18.3 0.0 1.4 8.1 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGD85007.1 - 0.0028 17.7 0.0 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EGD85007.1 - 0.089 13.4 0.7 0.98 10.0 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGD85007.1 - 0.095 11.9 0.0 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EGD85007.1 - 0.19 10.4 0.4 0.38 9.4 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein PsbH PF00737.20 EGD85008.1 - 0.08 12.7 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Malate_synthase PF01274.22 EGD85009.2 - 8.2e-226 750.3 0.0 9.2e-226 750.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 EGD85009.2 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Podoplanin PF05808.11 EGD85010.2 - 0.00016 21.8 0.5 0.00042 20.5 0.5 1.6 1 0 0 1 1 1 1 Podoplanin DUF575 PF04746.12 EGD85010.2 - 0.001 19.3 0.4 0.0018 18.5 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF575) DAP10 PF07213.11 EGD85010.2 - 0.031 14.2 1.3 0.69 9.9 0.1 2.4 2 0 0 2 2 2 0 DAP10 membrane protein TMEM154 PF15102.6 EGD85010.2 - 0.044 13.7 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family PspB PF06667.12 EGD85010.2 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Phage shock protein B DUF1180 PF06679.12 EGD85010.2 - 9 6.7 6.9 12 6.3 2.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Methyltransf_23 PF13489.6 EGD85012.1 - 3.9e-21 75.6 0.0 3.9e-21 75.6 0.0 2.7 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD85012.1 - 9.2e-15 55.1 0.0 2.4e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD85012.1 - 2.2e-13 50.7 0.0 5e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD85012.1 - 5.2e-11 42.6 3.2 1.4e-10 41.1 0.0 2.7 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD85012.1 - 2.6e-10 40.9 0.4 1.3e-09 38.6 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 EGD85012.1 - 2.3e-06 27.1 0.0 5.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGD85012.1 - 4.4e-05 22.9 0.0 0.00076 18.9 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EGD85012.1 - 0.00018 20.9 0.0 0.0035 16.6 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 EGD85012.1 - 0.0003 20.4 0.0 0.005 16.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EGD85012.1 - 0.0099 15.3 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EGD85012.1 - 0.022 14.9 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase TFIIA PF03153.13 EGD85012.1 - 0.022 14.8 28.1 0.027 14.5 28.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_16 PF10294.9 EGD85012.1 - 0.026 14.3 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_PK PF05891.12 EGD85012.1 - 0.14 11.6 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase GidB PF02527.15 EGD85012.1 - 0.21 10.9 0.0 0.45 9.8 0.0 1.6 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.17 EGD85012.1 - 0.22 11.0 3.3 0.25 10.8 0.0 2.5 3 0 0 3 3 2 0 Putative methyltransferase Nop53 PF07767.11 EGD85012.1 - 0.93 8.8 17.1 1.4 8.3 17.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Macoilin PF09726.9 EGD85012.1 - 3.9 5.9 8.8 4.8 5.6 8.8 1.1 1 0 0 1 1 1 0 Macoilin family Pox_Ag35 PF03286.14 EGD85012.1 - 4.3 7.1 8.2 6.8 6.4 8.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PPP1R26_N PF15740.5 EGD85012.1 - 8.9 4.8 16.4 20 3.6 16.2 1.5 1 1 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 26 N-terminus FAD_binding_3 PF01494.19 EGD85013.1 - 1.3e-21 77.3 2.4 3.7e-13 49.4 1.2 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EGD85013.1 - 8.4e-06 25.3 0.0 0.0045 16.3 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGD85013.1 - 0.00011 22.3 0.2 0.00033 20.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGD85013.1 - 0.00056 20.4 0.0 0.014 15.9 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGD85013.1 - 0.0016 17.7 0.1 0.1 11.8 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGD85013.1 - 0.0018 17.4 1.2 0.0049 16.0 0.2 2.1 2 1 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.24 EGD85013.1 - 0.0031 16.9 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 EGD85013.1 - 0.0074 15.9 0.2 0.11 12.1 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGD85013.1 - 0.01 14.9 0.1 0.022 13.8 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EGD85013.1 - 0.012 14.3 0.2 0.16 10.6 0.3 2.0 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 EGD85013.1 - 0.095 12.6 0.0 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MPC PF03650.13 EGD85014.1 - 1e-47 160.8 0.2 1.6e-47 160.2 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Enoyl_reductase PF12241.8 EGD85014.1 - 0.036 13.4 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region L51_S25_CI-B8 PF05047.16 EGD85015.2 - 3.5e-13 49.3 0.0 4.7e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Sel1 PF08238.12 EGD85016.1 - 5.3e-50 166.7 24.6 3.4e-09 37.1 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat Synaptobrevin PF00957.21 EGD85017.2 - 8.1e-32 108.9 0.8 1.3e-31 108.2 0.8 1.3 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 EGD85017.2 - 0.12 13.0 0.1 0.28 11.8 0.1 1.6 1 1 0 1 1 1 0 AT-hook-containing transcription factor NAT PF04768.13 EGD85018.1 - 5.7e-52 175.8 0.1 1.2e-51 174.7 0.0 1.6 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EGD85018.1 - 9.1e-32 110.0 0.0 2.8e-31 108.4 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EGD85018.1 - 5.6e-28 98.2 0.3 1.6e-27 96.6 0.0 1.8 2 0 0 2 2 2 1 Amino acid kinase family Rad21_Rec8_N PF04825.13 EGD85019.1 - 7.2e-32 109.8 0.0 1.8e-31 108.5 0.0 1.7 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGD85019.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Hydrolase_like PF13242.6 EGD85019.1 - 0.069 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like DUF4006 PF13179.6 EGD85019.1 - 0.2 11.6 0.1 0.41 10.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Glyco_hydro_76 PF03663.14 EGD85020.1 - 1e-151 505.6 15.5 1.2e-151 505.4 15.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGD85020.1 - 3.4e-06 26.4 5.7 0.013 14.6 0.2 3.2 3 0 0 3 3 3 3 Glycosyl Hydrolase Family 88 CBP4 PF07960.11 EGD85021.1 - 2.4e-29 101.8 0.5 2.5e-29 101.7 0.5 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 EGD85021.1 - 0.094 12.6 0.1 0.14 12.1 0.1 1.3 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Tmemb_161AB PF10268.9 EGD85021.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.2 1 1 0 1 1 1 0 Predicted transmembrane protein 161AB BTB PF00651.31 EGD85022.1 - 0.0014 18.9 0.1 0.006 16.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain adh_short_C2 PF13561.6 EGD85023.1 - 2.1e-60 204.2 0.2 2.3e-60 204.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD85023.1 - 4.4e-42 143.8 0.1 5.6e-42 143.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD85023.1 - 1.2e-11 44.9 0.7 1.9e-11 44.2 0.7 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EGD85023.1 - 0.00011 22.1 0.2 0.00021 21.2 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EGD85023.1 - 0.00035 21.2 0.0 0.00075 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 EGD85023.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGD85023.1 - 0.016 14.7 0.1 0.023 14.1 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lig_C PF18330.1 EGD85023.1 - 0.045 13.8 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region RecC_C PF17946.1 EGD85023.1 - 0.046 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 RecC C-terminal domain 3Beta_HSD PF01073.19 EGD85023.1 - 0.059 12.4 0.1 0.26 10.2 0.1 1.9 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 EGD85023.1 - 0.06 12.7 0.2 0.16 11.3 0.2 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.23 EGD85023.1 - 0.062 13.4 0.9 0.28 11.3 0.5 2.0 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 EGD85023.1 - 0.16 12.8 0.0 0.32 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ChuX_HutX PF06228.13 EGD85023.1 - 0.16 11.7 0.0 13 5.6 0.0 2.3 1 1 0 2 2 2 0 Haem utilisation ChuX/HutX Eno-Rase_NADH_b PF12242.8 EGD85023.1 - 0.43 10.4 2.7 7.2 6.5 0.6 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Myco_arth_vir_N PF09610.10 EGD85023.1 - 0.73 10.0 3.7 8.7 6.5 1.4 2.5 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Gln-synt_C PF00120.24 EGD85024.1 - 7.4e-76 255.4 0.0 9.7e-76 255.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain AdoMet_MTase PF07757.13 EGD85026.2 - 4e-36 123.7 0.0 1e-18 67.7 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 EGD85026.2 - 0.059 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SMC_N PF02463.19 EGD85027.1 - 1.9e-22 79.8 0.1 3.3e-22 79.0 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGD85027.1 - 2.2e-16 60.9 7.3 2.2e-16 60.9 7.3 5.2 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.6 EGD85027.1 - 1.2e-11 45.0 0.3 4.5e-08 33.2 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EGD85027.1 - 0.00067 19.6 4.6 0.068 13.0 0.0 3.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGD85027.1 - 0.001 18.8 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Baculo_PEP_C PF04513.12 EGD85027.1 - 0.01 15.9 12.8 1.1 9.3 0.6 4.2 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_25 PF13481.6 EGD85027.1 - 0.035 13.7 2.8 0.76 9.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGD85027.1 - 0.081 12.8 0.1 0.5 10.3 0.0 2.3 2 0 0 2 2 2 0 NACHT domain DUF3027 PF11228.8 EGD85027.1 - 0.23 11.5 1.3 1.2 9.2 1.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3027) Snapin_Pallidin PF14712.6 EGD85027.1 - 0.3 11.5 55.1 0.68 10.4 2.3 7.8 4 2 3 7 7 7 0 Snapin/Pallidin AAA_27 PF13514.6 EGD85027.1 - 0.34 10.5 0.0 0.34 10.5 0.0 4.1 3 2 1 4 4 4 0 AAA domain WXG100 PF06013.12 EGD85027.1 - 6.6 7.1 12.0 7.1 6.9 0.0 5.5 5 1 0 5 5 5 0 Proteins of 100 residues with WXG RGS PF00615.19 EGD85028.2 - 1.7e-06 28.3 0.0 0.0013 19.0 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF2892 PF11127.8 EGD85028.2 - 8.2 6.6 6.3 13 5.9 5.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Lipase_3 PF01764.25 EGD85029.2 - 3.8e-17 62.5 0.0 1.6e-12 47.5 0.0 2.5 1 1 1 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.7 EGD85029.2 - 0.022 15.3 0.6 0.038 14.6 0.6 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGD85029.2 - 0.082 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 BBS2_C PF14782.6 EGD85030.1 - 0.012 14.4 4.1 0.015 14.1 4.1 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal UPF0242 PF06785.11 EGD85030.1 - 0.14 12.3 8.7 0.15 12.2 8.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DASH_Hsk3 PF08227.11 EGD85031.1 - 1.2e-20 73.6 4.5 1.7e-20 73.1 4.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Sec2p PF06428.11 EGD85031.1 - 0.076 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p ApbA PF02558.16 EGD85032.2 - 3.9e-25 88.3 0.0 6.3e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EGD85032.2 - 7.6e-24 84.3 0.0 1.2e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Ank_2 PF12796.7 EGD85033.1 - 5.5e-40 135.8 4.8 1.3e-11 44.9 0.0 6.4 4 3 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD85033.1 - 8.1e-26 90.1 8.8 7.9e-06 26.3 0.0 9.7 6 2 5 11 11 11 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGD85033.1 - 1.2e-24 86.0 12.2 8.8e-06 25.9 0.1 8.4 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD85033.1 - 2.5e-17 61.2 13.4 0.0037 17.6 0.1 9.9 11 0 0 11 11 11 4 Ankyrin repeat Ank PF00023.30 EGD85033.1 - 2.3e-12 46.7 14.0 0.00023 21.5 0.1 8.4 10 0 0 10 10 10 3 Ankyrin repeat Sacchrp_dh_NADP PF03435.18 EGD85033.1 - 0.00051 20.3 0.7 0.073 13.3 0.2 2.9 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain DEAD PF00270.29 EGD85035.1 - 1.1e-36 126.3 0.0 1.8e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD85035.1 - 1.4e-26 93.0 0.0 5e-24 84.8 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGD85035.1 - 3.1e-09 37.1 0.0 6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGD85035.1 - 0.00078 18.9 0.0 0.0041 16.5 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Orbi_VP6 PF01516.16 EGD85035.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 Rpr2 PF04032.16 EGD85036.1 - 4.4e-24 84.6 0.5 9.1e-24 83.6 0.5 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Citrate_ly_lig PF08218.11 EGD85036.1 - 0.046 13.4 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain zf-Sec23_Sec24 PF04810.15 EGD85036.1 - 0.12 12.4 1.1 0.72 9.9 1.1 2.2 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger NAC PF01849.18 EGD85037.2 - 1.2e-24 86.0 0.5 1.2e-24 86.0 0.5 1.6 2 0 0 2 2 2 1 NAC domain Sigma70_ner PF04546.13 EGD85037.2 - 0.68 9.8 6.4 0.64 9.9 1.7 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region adh_short PF00106.25 EGD85038.1 - 7.8e-22 77.7 0.0 1.1e-17 64.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGD85038.1 - 7.3e-11 42.1 0.0 1.8e-07 31.0 0.0 2.5 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD85038.1 - 2.1e-09 37.5 0.0 3.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGD85038.1 - 0.0026 16.9 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EGD85038.1 - 0.066 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GTP1_OBG PF01018.22 EGD85038.1 - 0.19 11.3 1.4 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 GTP1/OBG zf-C2H2 PF00096.26 EGD85039.1 - 8.7e-09 35.4 11.2 0.00051 20.3 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGD85039.1 - 6.2e-05 23.2 10.4 6.2e-05 23.2 1.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGD85039.1 - 0.00061 20.4 9.8 0.12 13.3 1.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EGD85039.1 - 0.032 14.6 3.1 0.077 13.4 1.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGD85039.1 - 0.11 12.5 0.7 0.11 12.5 0.7 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EGD85039.1 - 0.45 10.7 3.0 11 6.3 0.2 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zf-BED PF02892.15 EGD85039.1 - 2.9 8.0 7.6 1 9.5 1.0 2.4 2 0 0 2 2 2 0 BED zinc finger TRP PF06011.12 EGD85046.2 - 1.1e-75 255.0 26.0 2.6e-75 253.8 26.0 1.5 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGD85046.2 - 2e-07 31.5 0.0 3.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 ML-like domain PIG-F PF06699.11 EGD85046.2 - 0.0076 16.4 1.9 0.0076 16.4 1.9 3.0 3 0 0 3 3 3 1 GPI biosynthesis protein family Pig-F BTB PF00651.31 EGD85047.2 - 2.7e-27 95.2 0.0 8.1e-14 51.8 0.2 2.9 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 EGD85047.2 - 0.029 15.0 0.1 14 6.4 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGD85047.2 - 0.039 14.6 0.1 0.42 11.2 0.1 2.3 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Pkinase PF00069.25 EGD85048.2 - 5e-25 88.4 0.2 1.1e-24 87.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85048.2 - 4.5e-19 68.8 0.0 8.8e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF99 PF01949.16 EGD85048.2 - 0.31 10.4 1.2 0.46 9.9 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF99 ALMT PF11744.8 EGD85048.2 - 1.6 7.5 6.1 3 6.6 6.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Wbp11 PF09429.10 EGD85049.1 - 4.5e-20 71.8 16.6 4.5e-20 71.8 16.6 2.0 3 0 0 3 3 3 1 WW domain binding protein 11 Nkap_C PF06047.11 EGD85049.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.5 2 1 1 3 3 3 0 NF-kappa-B-activating protein C-terminal domain GHMP_kinases_C PF08544.13 EGD85049.1 - 0.23 11.9 2.3 24 5.4 0.4 2.6 2 0 0 2 2 2 0 GHMP kinases C terminal DUF1176 PF06674.11 EGD85049.1 - 2.9 7.3 5.8 0.26 10.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1176) DUF1664 PF07889.12 EGD85051.2 - 0.0068 16.4 1.6 0.44 10.6 0.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EGD85051.2 - 0.0086 16.4 0.9 0.12 12.7 0.4 2.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Snf7 PF03357.21 EGD85051.2 - 0.063 12.9 1.1 0.12 11.9 0.9 1.6 1 1 0 1 1 1 0 Snf7 Hrs_helical PF12210.8 EGD85051.2 - 0.097 13.2 2.7 9.7 6.8 0.3 2.6 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Adenylsucc_synt PF00709.21 EGD85051.2 - 0.11 11.4 0.1 0.17 10.8 0.0 1.3 1 1 0 1 1 1 0 Adenylosuccinate synthetase Fib_alpha PF08702.10 EGD85051.2 - 0.19 11.9 2.1 0.32 11.2 2.1 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Nup35_RRM PF05172.13 EGD85052.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FAD_binding_3 PF01494.19 EGD85053.1 - 3.2e-71 240.4 0.3 2.9e-69 234.0 0.3 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGD85053.1 - 4.5e-34 117.9 0.0 1.6e-33 116.1 0.0 1.9 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 EGD85053.1 - 0.014 14.5 0.0 0.048 12.7 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.14 EGD85053.1 - 0.08 11.8 0.4 0.42 9.4 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_8 PF08022.12 EGD85054.1 - 1.3e-19 70.3 0.0 3.1e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EGD85054.1 - 2.9e-19 69.7 0.0 1.6e-18 67.3 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGD85054.1 - 6.4e-19 68.3 11.6 1.5e-18 67.1 11.6 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Ctr PF04145.15 EGD85055.2 - 2.9e-27 96.1 0.0 4.1e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Abhydrolase_2 PF02230.16 EGD85057.1 - 3e-58 197.2 0.0 3.5e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EGD85057.1 - 5.2e-08 32.6 0.0 1.7e-05 24.4 0.0 2.9 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 EGD85057.1 - 8.5e-07 28.7 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 EGD85057.1 - 5.3e-05 23.0 0.0 0.00018 21.2 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EGD85057.1 - 5.4e-05 23.1 0.0 0.02 14.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD85057.1 - 0.00037 19.8 1.3 0.02 14.2 0.0 2.9 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGD85057.1 - 0.011 16.3 0.0 0.13 12.8 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 EGD85057.1 - 0.037 13.7 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 EGD85057.1 - 0.096 12.6 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.14 EGD85057.1 - 0.22 11.0 0.0 10 5.6 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF1687 PF07955.11 EGD85058.1 - 3.4e-26 92.2 0.0 4.6e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) 1-cysPrx_C PF10417.9 EGD85058.1 - 0.059 13.2 0.0 8.8 6.3 0.0 2.5 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin Pkinase PF00069.25 EGD85059.1 - 7.8e-61 205.7 0.0 3.8e-60 203.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85059.1 - 3.1e-29 102.0 0.5 2.5e-20 72.9 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGD85059.1 - 0.00013 21.9 2.2 0.43 10.5 0.1 3.5 2 1 1 3 3 3 3 Phosphotransferase enzyme family Pkinase_C PF00433.24 EGD85059.1 - 0.0003 21.4 1.0 0.00082 20.0 1.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGD85059.1 - 0.00036 19.9 0.5 0.0017 17.7 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EGD85059.1 - 0.027 13.4 0.0 0.045 12.7 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EGD85059.1 - 0.04 13.3 0.1 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans_2 PF11951.8 EGD85060.1 - 5.2e-53 180.2 0.0 6.4e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD85060.1 - 1.1e-07 31.9 9.8 1.1e-07 31.9 9.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EGD85062.1 - 3.2e-39 134.8 13.7 3.8e-33 114.9 12.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGD85062.1 - 9.5e-10 37.4 4.5 9.5e-10 37.4 4.5 2.7 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EGD85062.1 - 1.4e-09 37.4 10.0 2e-07 30.3 3.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EGD85062.1 - 5e-06 26.1 2.0 0.0047 16.3 0.3 2.5 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 EGD85062.1 - 0.0017 16.9 6.0 0.011 14.1 4.1 2.6 2 1 1 3 3 3 2 Transmembrane secretion effector MscS_TM PF12794.7 EGD85062.1 - 0.0097 14.8 0.3 0.034 13.0 0.3 1.9 1 1 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 Homeodomain PF00046.29 EGD85063.2 - 1.7e-12 47.0 0.0 4.6e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Homeodomain DUF917 PF06032.12 EGD85064.2 - 1.4e-116 389.2 0.5 1.5e-76 257.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EGD85064.2 - 1.2e-30 106.8 5.1 8.9e-26 90.8 0.9 3.3 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGD85064.2 - 6.4e-28 97.7 1.4 1.6e-25 89.9 0.1 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EGD85064.2 - 4e-05 22.4 1.8 0.05 12.2 0.2 2.6 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 EGD85064.2 - 0.0012 18.4 3.2 0.0095 15.5 0.2 3.2 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DUF3715 PF12509.8 EGD85064.2 - 0.056 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) BRE PF06113.12 EGD85064.2 - 0.09 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) FtsA PF14450.6 EGD85064.2 - 0.095 13.1 5.6 7.3 7.1 0.2 3.6 3 1 0 3 3 3 0 Cell division protein FtsA MreB_Mbl PF06723.13 EGD85064.2 - 4 6.2 10.0 0.17 10.7 2.5 2.6 2 1 0 2 2 2 0 MreB/Mbl protein Pyridoxal_deC PF00282.19 EGD85065.1 - 9.1e-61 205.6 0.0 1.3e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGD85065.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V DSPn PF14671.6 EGD85067.1 - 2.5e-39 135.0 0.0 1.8e-37 128.9 0.0 2.7 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EGD85067.1 - 8.5e-16 58.0 0.0 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGD85067.1 - 6.5e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pcc1 PF09341.10 EGD85068.2 - 2.3e-33 114.2 2.0 2.8e-33 113.9 2.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Translin PF01997.16 EGD85069.1 - 1.3e-54 185.3 0.0 1.6e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 Translin family Rx_N PF18052.1 EGD85069.1 - 0.0049 17.1 0.9 0.65 10.3 0.4 3.2 2 1 0 2 2 2 1 Rx N-terminal domain Syntaxin_2 PF14523.6 EGD85069.1 - 0.058 13.8 2.0 0.16 12.4 0.5 2.4 3 0 0 3 3 3 0 Syntaxin-like protein Syntaxin-6_N PF09177.11 EGD85069.1 - 0.061 13.9 0.7 0.28 11.8 0.2 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Ribosomal_L22e PF01776.17 EGD85070.1 - 1.9e-46 156.9 0.6 2.3e-46 156.7 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF676 PF05057.14 EGD85072.2 - 0.0041 16.7 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_6 PF13344.6 EGD85074.1 - 1e-23 83.3 0.0 2.2e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGD85074.1 - 4e-12 46.0 0.0 2.2e-11 43.6 0.0 2.3 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 EGD85074.1 - 0.02 15.2 0.0 13 6.0 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase RR_TM4-6 PF06459.12 EGD85075.1 - 0.042 13.7 2.6 0.052 13.4 2.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GSHPx PF00255.19 EGD85076.1 - 9.7e-40 134.5 0.0 1.3e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EGD85076.1 - 0.031 14.2 0.0 0.09 12.7 0.0 1.9 1 1 0 1 1 1 0 AhpC/TSA family p450 PF00067.22 EGD85079.1 - 1.3e-56 192.3 0.0 2.6e-55 188.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 ATP-synt_C PF00137.21 EGD85081.1 - 2.4e-36 123.9 34.2 5.1e-22 78.0 15.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF1713 PF08213.11 EGD85082.1 - 1.2e-10 41.1 22.0 1.2e-10 41.1 22.0 1.8 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 EGD85082.1 - 0.01 16.5 0.7 0.024 15.3 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 G-alpha PF00503.20 EGD85083.1 - 1.4e-108 363.3 0.0 1.6e-108 363.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGD85083.1 - 1.6e-13 50.5 1.3 5.6e-09 35.7 0.0 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGD85083.1 - 6.6e-07 28.9 0.1 0.00089 18.7 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region BsuBI_PstI_RE PF06616.11 EGD85083.1 - 0.0016 17.8 0.1 0.0027 17.0 0.1 1.3 1 0 0 1 1 1 1 BsuBI/PstI restriction endonuclease domain Roc PF08477.13 EGD85083.1 - 0.0051 17.0 0.3 1.4 9.2 0.0 2.7 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGD85083.1 - 0.013 15.6 0.0 4.2 7.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase TniB PF05621.11 EGD85083.1 - 0.016 14.6 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 EGD85083.1 - 0.084 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EGD85083.1 - 0.09 12.1 0.1 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Spermine_synth PF01564.17 EGD85086.2 - 7.5e-70 234.2 0.0 1.1e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EGD85086.2 - 3.9e-23 81.1 0.1 7.5e-23 80.2 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EGD85086.2 - 0.00016 22.3 0.0 0.00035 21.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD85086.2 - 0.00081 19.2 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD85086.2 - 0.0018 19.0 0.2 0.008 16.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 EGD85086.2 - 0.0095 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain MTS PF05175.14 EGD85086.2 - 0.095 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 EGD85086.2 - 0.15 12.0 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Transketolase_N PF00456.21 EGD85087.1 - 1.3e-151 504.2 0.0 1.8e-151 503.9 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EGD85087.1 - 6.2e-46 156.3 0.0 9.8e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGD85087.1 - 3.6e-12 46.3 0.0 7.6e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EGD85087.1 - 2.6e-05 23.6 0.0 7.2e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 EGD85087.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Mur_ligase_C PF02875.21 EGD85087.1 - 0.13 12.5 0.0 0.47 10.7 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain TPP_enzyme_C PF02775.21 EGD85087.1 - 0.42 10.4 7.4 0.088 12.6 1.1 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fungal_trans PF04082.18 EGD85088.1 - 9e-31 106.9 0.5 1.6e-30 106.0 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD85088.1 - 1.4e-09 37.9 11.7 2.1e-09 37.3 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trimer_CC PF08954.11 EGD85088.1 - 0.022 14.3 1.5 0.063 12.9 1.5 1.8 1 0 0 1 1 1 0 Trimerisation motif bZIP_1 PF00170.21 EGD85088.1 - 0.21 11.7 0.6 0.56 10.3 0.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor PKcGMP_CC PF16808.5 EGD85088.1 - 1.6 8.6 4.1 1 9.3 1.3 2.0 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SET PF00856.28 EGD85091.2 - 0.0016 18.8 0.0 0.0033 17.8 0.0 1.6 1 1 0 1 1 1 1 SET domain MMR_HSR1_C PF08438.10 EGD85093.2 - 1.4e-36 125.4 0.0 3.1e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EGD85093.2 - 7.5e-21 74.3 0.0 3.4e-20 72.3 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGD85093.2 - 4.4e-09 36.1 0.0 1.5e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGD85093.2 - 0.0042 17.0 0.9 0.12 12.2 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EGD85093.2 - 0.0047 16.5 0.4 0.6 9.6 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGD85093.2 - 0.027 14.5 1.8 0.15 12.2 0.3 2.5 3 0 0 3 3 3 0 Dynamin family ABC_tran PF00005.27 EGD85093.2 - 0.04 14.4 0.1 0.72 10.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 EGD85093.2 - 0.077 12.8 0.1 8.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 EGD85093.2 - 0.089 12.8 0.2 0.33 11.0 0.1 1.9 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain KTI12 PF08433.10 EGD85093.2 - 0.11 11.9 0.1 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Ploopntkinase3 PF18751.1 EGD85093.2 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Ribosomal_L7Ae PF01248.26 EGD85096.1 - 7.4e-18 64.1 5.1 8.8e-18 63.8 1.8 2.5 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rib_recp_KP_reg PF05104.12 EGD85096.1 - 1.4 10.0 26.2 0.027 15.5 15.2 2.2 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Band_7 PF01145.25 EGD85098.1 - 1.4e-24 87.1 8.0 3.3e-24 85.9 8.0 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EGD85098.1 - 0.0009 18.4 4.3 0.0013 17.9 4.3 1.3 1 0 0 1 1 1 1 SigmaW regulon antibacterial GatB_Yqey PF02637.18 EGD85098.1 - 0.023 14.6 0.6 0.04 13.8 0.6 1.4 1 0 0 1 1 1 0 GatB domain Methyltransf_34 PF11312.8 EGD85100.1 - 1.5e-100 336.4 0.0 2.7e-100 335.6 0.0 1.3 2 0 0 2 2 2 1 Putative SAM-dependent methyltransferase PAF-AH_p_II PF03403.13 EGD85101.1 - 1.8e-14 53.0 0.0 2.4e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 EGD85101.1 - 0.00017 20.9 0.0 0.1 11.8 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EGD85101.1 - 0.0011 17.9 0.2 0.004 16.1 0.2 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 EGD85101.1 - 0.022 14.4 0.0 0.21 11.2 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EGD85101.1 - 0.024 14.4 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family BAAT_C PF08840.11 EGD85101.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Nop14 PF04147.12 EGD85102.1 - 0.26 9.5 15.4 0.05 11.8 5.2 2.2 2 0 0 2 2 2 0 Nop14-like family BSP_II PF05432.11 EGD85102.1 - 4.8 6.8 17.7 3.2 7.4 6.8 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF202 PF02656.15 EGD85105.1 - 5.2e-22 78.1 0.3 5.2e-22 78.1 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PTPA PF03095.15 EGD85107.1 - 1.5e-107 359.5 0.0 1.8e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF1754 PF08555.10 EGD85108.1 - 1.2e-15 58.1 20.9 1.2e-15 58.1 20.9 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.10 EGD85108.1 - 0.041 13.3 17.3 0.046 13.1 17.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 EccE PF11203.8 EGD85108.1 - 0.15 12.4 3.5 0.096 13.0 0.9 1.7 1 1 1 2 2 2 0 Putative type VII ESX secretion system translocon, EccE HSP70 PF00012.20 EGD85108.1 - 0.6 8.2 12.0 0.7 8.0 12.0 1.0 1 0 0 1 1 1 0 Hsp70 protein CDC45 PF02724.14 EGD85108.1 - 3 6.0 20.9 3.5 5.8 20.9 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EGD85108.1 - 3.1 6.2 7.9 3.9 5.9 7.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RR_TM4-6 PF06459.12 EGD85108.1 - 7.5 6.3 13.7 9.7 5.9 13.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-AN1 PF01428.16 EGD85109.2 - 2.3e-13 50.1 4.2 2.3e-13 50.1 4.2 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EGD85109.2 - 0.01 16.1 4.0 0.01 16.1 4.0 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DLH PF01738.18 EGD85111.1 - 8.8e-15 54.8 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EGD85111.1 - 0.11 12.1 0.0 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Zn_clus PF00172.18 EGD85112.1 - 5.5e-08 32.8 6.6 8e-08 32.3 6.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.27 EGD85116.2 - 5.9e-15 54.6 1.3 1.2e-14 53.7 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EGD85116.2 - 0.11 12.0 0.2 0.24 11.0 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 EGD85116.2 - 0.25 11.5 0.2 0.42 10.8 0.2 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) p450 PF00067.22 EGD85118.1 - 1.2e-61 208.9 0.0 1.5e-61 208.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 EGD85121.2 - 6.1e-09 35.8 11.5 0.0003 21.1 4.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGD85121.2 - 1.8e-07 31.3 6.2 1.8e-05 24.9 2.3 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGD85121.2 - 5.8e-06 26.7 8.1 0.028 15.2 2.5 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGD85121.2 - 0.0024 17.8 5.4 0.45 10.6 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 EGD85121.2 - 0.53 10.8 7.7 3.8 8.0 1.4 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 EGD85121.2 - 0.9 10.0 11.2 0.92 10.0 1.1 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGD85121.2 - 1.3 9.4 13.4 1 9.7 0.1 3.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding THAP PF05485.12 EGD85123.1 - 0.052 14.5 0.1 0.073 14.0 0.1 1.3 1 0 0 1 1 1 0 THAP domain Smg4_UPF3 PF03467.15 EGD85124.1 - 2.2e-41 141.8 0.0 2.2e-41 141.8 0.0 3.4 3 2 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 EGD85124.1 - 1e-08 34.9 0.3 1.9e-07 30.8 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AbiJ_NTD3 PF18860.1 EGD85124.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 AbiJ N-terminal domain 3 Ctr PF04145.15 EGD85125.1 - 2.5e-40 138.5 0.2 3.1e-40 138.2 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family TraL PF07178.11 EGD85125.1 - 0.36 11.3 2.8 14 6.3 0.3 2.2 2 0 0 2 2 2 0 TraL protein DIOX_N PF14226.6 EGD85126.1 - 2.5e-09 37.9 0.0 4.8e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGD85126.1 - 7.1e-06 26.4 0.0 0.00032 21.1 0.0 2.3 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.28 EGD85127.1 - 6.4e-32 111.7 0.0 1.5e-27 97.4 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EGD85127.1 - 0.0024 17.6 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Aldedh PF00171.22 EGD85128.1 - 8.6e-185 614.7 0.2 9.7e-185 614.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGD85128.1 - 0.16 11.4 0.0 18 4.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) GST_C PF00043.25 EGD85129.1 - 3.8e-15 55.9 0.0 7.7e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGD85129.1 - 2.1e-10 40.9 0.0 4.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGD85129.1 - 5.2e-10 39.5 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGD85129.1 - 1.2e-09 38.4 0.0 2.2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGD85129.1 - 4.3e-09 36.5 0.0 7.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGD85129.1 - 4.2e-08 33.1 0.0 8.7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GDPD PF03009.17 EGD85130.1 - 0.09 12.5 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Mre11_DNA_bind PF04152.14 EGD85131.1 - 9.7e-53 178.9 0.4 2e-52 177.9 0.4 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EGD85131.1 - 3.1e-14 54.0 1.1 2e-13 51.3 0.9 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGD85131.1 - 0.00024 21.3 0.1 0.003 17.8 0.0 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain CHIP_TPR_N PF18391.1 EGD85131.1 - 3 8.7 7.6 0.29 11.9 1.2 2.5 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain HNH_2 PF13391.6 EGD85132.1 - 1.7e-12 47.3 0.0 3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease SPAN PF02510.14 EGD85132.1 - 0.079 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens protein F-box-like PF12937.7 EGD85133.2 - 1.3e-08 34.6 0.3 2.7e-08 33.6 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD85133.2 - 5.5e-08 32.5 1.3 1.1e-07 31.6 1.3 1.4 1 0 0 1 1 1 1 F-box domain Snf7 PF03357.21 EGD85134.1 - 1.7e-20 73.3 14.6 1.8e-20 73.2 12.0 1.9 1 1 1 2 2 2 1 Snf7 MerR-DNA-bind PF09278.11 EGD85134.1 - 0.72 10.4 11.9 2.2 8.9 1.1 3.7 4 0 0 4 4 4 0 MerR, DNA binding TPR_MLP1_2 PF07926.12 EGD85134.1 - 8.7 6.4 15.4 0.12 12.4 4.7 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DFRP_C PF16543.5 EGD85136.1 - 8.9e-26 90.2 9.6 8.9e-26 90.2 9.6 3.5 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 EGD85136.1 - 4.9e-06 27.2 4.5 4.9e-06 27.2 4.5 4.0 2 2 2 4 4 4 2 Torus domain zf-CCCH_4 PF18044.1 EGD85136.1 - 5.8e-05 22.8 10.2 0.00087 19.0 2.7 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 EGD85136.1 - 0.00033 20.5 1.3 0.00033 20.5 1.3 2.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGD85136.1 - 0.0012 18.8 6.7 0.0012 18.8 6.7 3.3 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_3 PF15663.5 EGD85136.1 - 0.1 12.8 6.2 0.58 10.4 0.9 2.7 1 1 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGD85136.1 - 0.24 11.9 14.5 0.32 11.5 4.4 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Ribosomal_L26 PF16906.5 EGD85139.1 - 3.8e-39 133.0 3.0 4.7e-39 132.7 3.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EGD85139.1 - 9.7e-09 34.9 2.1 2e-08 33.9 2.1 1.6 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 EGD85139.1 - 0.011 15.8 0.1 0.012 15.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) Ion_trans PF00520.31 EGD85141.1 - 4.4e-08 32.7 28.4 6.8e-08 32.0 28.4 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EGD85141.1 - 0.00014 20.7 23.1 0.0048 15.6 23.1 2.1 1 1 0 1 1 1 1 Polycystin cation channel DUF2347 PF09804.9 EGD85141.1 - 0.28 10.7 0.6 0.54 9.8 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) CPSase_L_D2 PF02786.17 EGD85143.2 - 7e-115 381.8 0.2 3.3e-83 278.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.21 EGD85143.2 - 5.9e-46 156.2 0.1 1.4e-45 154.9 0.1 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EGD85143.2 - 6.1e-39 133.1 0.0 1.5e-38 131.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EGD85143.2 - 1.5e-32 112.8 0.0 4.7e-32 111.2 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EGD85143.2 - 2.3e-22 79.0 0.0 1.1e-21 76.8 0.0 2.3 2 0 0 2 2 2 1 MGS-like domain GATase PF00117.28 EGD85143.2 - 2.9e-19 69.6 0.0 1.7e-18 67.1 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Dala_Dala_lig_C PF07478.13 EGD85143.2 - 3.8e-18 65.8 0.4 3.5e-09 36.5 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGD85143.2 - 3.1e-16 59.4 0.1 3.3e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EGD85143.2 - 2.6e-10 40.1 0.0 3e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EGD85143.2 - 3.1e-06 27.3 0.3 0.016 15.3 0.1 2.9 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 EGD85143.2 - 0.00053 19.6 0.0 1.3 8.6 0.0 2.7 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.19 EGD85143.2 - 0.0055 16.5 0.1 1.4 8.6 0.0 2.9 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.18 EGD85143.2 - 0.067 13.5 0.1 0.55 10.5 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain ABC_tran PF00005.27 EGD85144.1 - 5.4e-21 75.6 0.0 1.8e-09 38.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGD85144.1 - 9.7e-06 25.6 3.7 0.0077 16.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGD85144.1 - 0.00034 20.8 0.0 0.058 13.6 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 EGD85144.1 - 0.027 13.6 0.1 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Ploopntkinase1 PF18748.1 EGD85144.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 AAA_23 PF13476.6 EGD85144.1 - 0.53 10.7 2.8 0.91 10.0 0.7 2.0 2 0 0 2 2 2 0 AAA domain Exo84_C PF16528.5 EGD85145.2 - 7.3e-69 231.7 0.1 7.3e-69 231.7 0.1 1.5 2 0 0 2 2 2 1 Exocyst component 84 C-terminal 7TMR-HDED PF07697.11 EGD85145.2 - 0.036 14.2 3.2 0.066 13.3 3.2 1.3 1 0 0 1 1 1 0 7TM-HD extracellular MAS20 PF02064.15 EGD85146.1 - 9.3e-44 148.6 0.3 1.1e-43 148.4 0.3 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Glyco_hydro_72 PF03198.14 EGD85147.1 - 4.9e-120 400.5 0.0 6.4e-120 400.1 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EGD85147.1 - 1.7e-05 24.4 0.0 0.00031 20.3 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ank_2 PF12796.7 EGD85148.2 - 2e-81 268.7 0.1 2.9e-16 59.8 0.7 7.8 4 3 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD85148.2 - 8.6e-61 201.6 1.5 1.6e-12 47.7 0.0 11.3 5 2 9 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD85148.2 - 5.8e-54 173.7 0.5 5.7e-05 23.2 0.0 15.5 17 0 0 17 17 17 10 Ankyrin repeat Ank PF00023.30 EGD85148.2 - 6.4e-44 146.5 0.7 2.3e-05 24.6 0.0 13.1 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.6 EGD85148.2 - 1.5e-41 139.9 4.4 5.9e-08 32.8 0.0 12.1 4 2 9 14 14 14 6 Ankyrin repeats (many copies) HeLo PF14479.6 EGD85148.2 - 2e-16 60.5 0.0 5.3e-15 55.8 0.0 2.5 1 1 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.12 EGD85148.2 - 5.6e-08 32.9 0.0 1.3e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 EGD85148.2 - 1.8e-05 24.1 0.2 3.6e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EGD85148.2 - 2.4e-05 24.6 0.0 7.5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGD85148.2 - 0.00016 22.1 0.0 0.00042 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EGD85148.2 - 0.0054 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 EGD85148.2 - 0.0077 16.2 0.0 0.019 14.9 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EGD85148.2 - 0.11 13.0 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 EGD85148.2 - 0.2 11.4 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein mono-CXXC PF15626.6 EGD85157.2 - 7.7 7.0 11.0 3.3 8.1 0.2 4.3 3 0 0 3 3 3 0 single CXXC unit DUF1269 PF06897.12 EGD85158.1 - 0.18 12.1 0.2 9.6 6.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) Amino_oxidase PF01593.24 EGD85159.1 - 1.3e-67 229.1 0.1 1.8e-67 228.6 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGD85159.1 - 1.7e-07 31.3 0.1 3.7e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HTH_ABP1_N PF18107.1 EGD85159.1 - 0.11 12.3 0.1 0.66 9.7 0.1 2.1 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain DAO PF01266.24 EGD85159.1 - 0.11 12.1 0.1 4.8 6.7 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.25 EGD85160.1 - 6.9e-23 81.1 0.0 1.1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD85160.1 - 1.9e-21 76.7 0.0 2.4e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD85160.1 - 0.0073 16.2 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 KR domain MlaE PF02405.16 EGD85160.1 - 0.051 13.2 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Permease MlaE DUF1776 PF08643.10 EGD85160.1 - 0.054 12.9 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MFS_1 PF07690.16 EGD85161.1 - 1.2e-33 116.5 23.8 1.6e-33 116.1 22.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 EGD85166.1 - 1.1e-48 166.0 0.0 2.4e-48 164.9 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD85166.1 - 0.00012 22.1 5.4 0.00024 21.2 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.27 EGD85167.2 - 9.6e-48 162.2 0.4 3.9e-26 92.2 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGD85167.2 - 5.7e-24 85.2 16.4 9.5e-24 84.5 16.3 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 EGD85167.2 - 3.2e-10 40.3 5.4 0.0073 16.1 0.1 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGD85167.2 - 9.5e-10 38.3 5.7 0.0014 18.1 0.1 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGD85167.2 - 5.2e-07 29.7 0.5 0.00065 19.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGD85167.2 - 7.1e-07 28.9 0.7 0.0063 16.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGD85167.2 - 2.8e-06 28.0 1.5 0.0028 18.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGD85167.2 - 5.3e-06 26.9 0.3 0.01 16.2 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EGD85167.2 - 2.4e-05 24.4 0.1 0.09 12.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 EGD85167.2 - 5e-05 23.7 0.9 0.023 15.1 0.0 3.7 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGD85167.2 - 5.6e-05 23.5 0.1 0.014 15.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGD85167.2 - 0.0001 22.1 0.1 4.5 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 EGD85167.2 - 0.00069 19.9 4.9 0.18 12.1 0.5 3.2 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 EGD85167.2 - 0.00076 19.3 0.6 0.024 14.3 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EGD85167.2 - 0.0026 17.3 0.2 0.48 9.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EGD85167.2 - 0.0038 17.0 1.1 0.44 10.2 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EGD85167.2 - 0.004 16.9 0.1 1.1 8.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EGD85167.2 - 0.0048 17.0 1.5 0.14 12.2 0.0 2.6 3 0 0 3 3 2 1 Dynamin family ATPase_2 PF01637.18 EGD85167.2 - 0.0048 16.8 1.3 0.31 10.9 0.0 2.9 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 EGD85167.2 - 0.0052 16.0 0.2 0.62 9.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) T2SSE PF00437.20 EGD85167.2 - 0.0059 15.7 0.3 0.14 11.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 EGD85167.2 - 0.006 16.9 0.1 2.2 8.7 0.0 3.4 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.17 EGD85167.2 - 0.0091 15.7 5.4 7.3 6.3 0.1 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein MeaB PF03308.16 EGD85167.2 - 0.02 13.9 0.3 0.81 8.6 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 EGD85167.2 - 0.021 14.0 5.3 0.28 10.3 0.5 2.8 2 2 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 EGD85167.2 - 0.027 14.5 0.1 0.34 10.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC_ATPase PF09818.9 EGD85167.2 - 0.029 13.2 2.6 0.88 8.3 0.1 3.3 3 1 0 3 3 3 0 Predicted ATPase of the ABC class Adeno_IVa2 PF02456.15 EGD85167.2 - 0.03 13.1 0.3 0.14 10.9 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein NTPase_1 PF03266.15 EGD85167.2 - 0.031 14.2 2.5 4.1 7.3 0.1 2.8 2 0 0 2 2 2 0 NTPase cobW PF02492.19 EGD85167.2 - 0.031 13.8 4.5 0.14 11.8 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EGD85167.2 - 0.037 14.6 0.0 6.2 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 EGD85167.2 - 0.047 12.6 0.5 10 4.9 0.0 2.5 2 1 0 2 2 2 0 AAA-like domain Roc PF08477.13 EGD85167.2 - 0.053 13.7 0.4 28 5.0 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 EGD85167.2 - 0.056 13.1 0.0 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 EGD85167.2 - 0.082 12.5 0.3 1.4 8.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGD85167.2 - 0.093 12.0 0.1 8.9 5.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Herpes_Helicase PF02689.14 EGD85167.2 - 0.12 10.2 0.1 7.7 4.3 0.0 2.1 2 0 0 2 2 2 0 Helicase AAA_33 PF13671.6 EGD85167.2 - 0.15 12.3 1.1 4.6 7.4 0.1 3.2 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EGD85167.2 - 0.15 11.4 1.0 6.2 6.1 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family UCR_UQCRX_QCR9 PF05365.12 EGD85167.2 - 0.18 11.8 1.9 0.46 10.5 1.9 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Rad17 PF03215.15 EGD85167.2 - 0.19 11.6 3.9 0.49 10.3 0.1 2.8 3 0 0 3 3 3 0 Rad17 P-loop domain DUF87 PF01935.17 EGD85167.2 - 0.33 11.0 3.7 1.2 9.2 0.5 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 EGD85167.2 - 0.44 10.6 1.8 10 6.1 0.1 3.3 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EGD85167.2 - 1.1 9.2 7.6 0.41 10.6 0.3 3.1 3 1 0 3 3 3 0 NACHT domain Condensation PF00668.20 EGD85168.2 - 0 1317.7 0.0 2.1e-56 191.5 0.0 11.1 10 3 0 10 10 10 10 Condensation domain AMP-binding PF00501.28 EGD85168.2 - 0 1266.5 0.0 5.6e-79 265.7 0.0 6.3 5 1 1 6 6 6 6 AMP-binding enzyme PP-binding PF00550.25 EGD85168.2 - 7.7e-74 244.0 6.3 3.3e-11 43.4 0.3 7.8 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGD85168.2 - 8e-13 49.2 0.1 0.0012 19.8 0.0 5.7 5 0 0 5 5 5 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EGD85168.2 - 1.1e-11 44.1 0.1 0.00025 19.9 0.0 5.1 6 0 0 6 6 6 4 Transferase family DUF5122 PF17164.4 EGD85168.2 - 0.37 11.1 1.5 21 5.5 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller GMP_synt_C PF00958.22 EGD85170.1 - 2.6e-42 142.8 0.0 5.1e-42 141.9 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EGD85170.1 - 1.7e-38 132.3 0.0 3e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EGD85170.1 - 1.4e-10 40.7 0.1 2.6e-06 26.7 0.1 2.5 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EGD85170.1 - 3.8e-07 30.1 0.1 6.8e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 EGD85170.1 - 0.0011 18.5 0.0 0.0084 15.6 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EGD85170.1 - 0.0028 16.5 0.1 0.007 15.2 0.1 1.7 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 EGD85170.1 - 0.0074 15.9 0.1 0.017 14.7 0.1 1.5 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 EGD85170.1 - 0.011 15.1 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.19 EGD85170.1 - 0.058 13.4 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 EGD85170.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 PP-loop family BCIP PF13862.6 EGD85171.1 - 2.2e-74 249.7 0.1 2.8e-74 249.4 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein VID27_N PF17748.1 EGD85171.1 - 0.1 12.5 0.4 0.19 11.6 0.4 1.4 1 0 0 1 1 1 0 VID27 N-terminal region DUF3507 PF12015.8 EGD85171.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) CENP-F_leu_zip PF10473.9 EGD85173.2 - 0.016 15.2 1.9 0.027 14.5 1.9 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 EGD85173.2 - 0.02 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PI3K_P85_iSH2 PF16454.5 EGD85173.2 - 0.029 14.0 1.8 0.088 12.4 1.3 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Sad1_UNC PF07738.13 EGD85174.2 - 1.9e-14 53.8 0.0 4.7e-09 36.3 0.0 2.5 2 1 0 2 2 2 2 Sad1 / UNC-like C-terminal Kinesin PF00225.23 EGD85175.1 - 1.1e-89 300.7 0.0 1.1e-89 300.7 0.0 3.3 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EGD85175.1 - 2.9e-19 69.5 0.0 1.2e-15 57.7 0.0 3.6 3 0 0 3 3 3 2 Microtubule binding SHE3 PF17078.5 EGD85175.1 - 0.0053 16.5 19.1 0.0053 16.5 19.1 8.5 4 2 4 8 8 8 1 SWI5-dependent HO expression protein 3 Glycos_transf_1 PF00534.20 EGD85176.1 - 1.9e-30 105.7 0.0 1.9e-28 99.1 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGD85176.1 - 2.4e-19 70.0 0.4 3.8e-19 69.3 0.4 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EGD85176.1 - 9.2e-14 52.0 0.0 4.3e-13 49.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGD85176.1 - 1.3e-09 38.7 0.6 2e-09 38.1 0.6 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGD85176.1 - 8.5e-05 22.9 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 EGD85176.1 - 0.031 14.3 0.0 7.7 6.5 0.0 2.4 2 0 0 2 2 2 0 ALG11 mannosyltransferase N-terminus Peptidase_M19 PF01244.21 EGD85177.2 - 5e-61 206.6 0.7 5.9e-61 206.4 0.7 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Mesd PF10185.9 EGD85177.2 - 0.2 11.6 0.4 7.8 6.4 0.1 2.1 1 1 1 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor ERCC4 PF02732.15 EGD85178.1 - 6.5e-24 84.9 0.1 6.5e-24 84.9 0.1 2.4 2 2 0 2 2 2 1 ERCC4 domain RCDG1 PF15725.5 EGD85178.1 - 4.6 7.7 8.4 0.77 10.2 1.3 3.0 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein MFS_1 PF07690.16 EGD85179.1 - 9.8e-18 64.2 20.9 9.8e-18 64.2 20.9 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EGD85179.1 - 0.00029 20.4 13.1 0.0046 16.5 0.4 3.6 4 0 0 4 4 4 2 Nodulin-like IPK PF03770.16 EGD85181.1 - 9.3e-57 192.1 0.0 2.4e-56 190.7 0.0 1.7 2 0 0 2 2 2 1 Inositol polyphosphate kinase Pam17 PF08566.10 EGD85181.1 - 0.042 13.7 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 LRR_4 PF12799.7 EGD85182.1 - 3.3e-23 81.4 44.5 3.5e-05 24.1 1.5 9.1 9 1 0 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGD85182.1 - 7.8e-19 67.2 44.2 6.4e-07 29.0 3.2 7.4 4 1 4 9 9 9 7 Leucine rich repeat LRR_9 PF14580.6 EGD85182.1 - 4.3e-11 42.6 11.3 1.2e-05 24.8 1.2 4.3 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 EGD85182.1 - 2.1 8.6 30.9 1.8 8.8 1.3 9.1 10 1 0 11 11 11 0 Leucine Rich repeat COesterase PF00135.28 EGD85183.2 - 2.4e-23 82.8 0.0 3.2e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGD85183.2 - 0.0032 17.4 0.0 0.0049 16.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD85183.2 - 0.056 14.0 0.2 0.091 13.4 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family peroxidase PF00141.23 EGD85186.1 - 1.1e-45 156.1 0.0 1.6e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4003 PF13170.6 EGD85186.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) TPR_1 PF00515.28 EGD85188.1 - 1.8e-06 27.5 2.1 1.1 9.1 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF3808 PF10300.9 EGD85188.1 - 4.6e-05 22.3 0.2 6.7e-05 21.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 EGD85188.1 - 0.0098 15.9 3.5 3 8.2 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGD85188.1 - 0.014 15.6 0.9 0.031 14.5 0.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGD85188.1 - 0.018 15.5 0.1 0.073 13.6 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat p450 PF00067.22 EGD85190.1 - 1.9e-43 148.9 0.0 2.6e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tymo_coat PF00983.18 EGD85190.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Tymovirus coat protein TnpW PF14202.6 EGD85190.1 - 0.18 11.6 2.7 7.2 6.5 0.1 3.1 3 0 0 3 3 3 0 Transposon-encoded protein TnpW ABC_tran PF00005.27 EGD85192.1 - 3.2e-72 241.5 0.0 1e-35 123.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGD85192.1 - 3.4e-59 200.8 13.5 1.9e-51 175.3 10.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGD85192.1 - 1.8e-17 63.5 0.6 8.4e-05 22.1 0.0 4.5 3 2 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGD85192.1 - 1e-08 35.7 8.4 9.6e-05 22.8 0.1 3.6 4 1 0 4 4 2 2 AAA ATPase domain AAA_22 PF13401.6 EGD85192.1 - 1.6e-08 34.9 1.0 0.0027 18.0 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EGD85192.1 - 9.9e-08 32.1 0.1 0.012 15.4 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EGD85192.1 - 1.1e-07 31.7 3.4 0.021 14.5 0.0 4.2 3 2 1 4 4 4 2 AAA domain AAA_29 PF13555.6 EGD85192.1 - 2.1e-07 30.6 0.5 0.024 14.4 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EGD85192.1 - 2.1e-07 30.1 0.4 0.0051 15.7 0.1 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 EGD85192.1 - 5.3e-07 29.7 0.0 0.0024 17.6 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGD85192.1 - 1.5e-06 28.2 0.0 0.017 15.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 EGD85192.1 - 5.1e-06 27.0 2.2 0.36 11.3 0.3 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EGD85192.1 - 5e-05 23.9 0.6 0.13 12.7 0.2 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EGD85192.1 - 0.00015 21.1 0.1 0.85 8.9 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin AAA_25 PF13481.6 EGD85192.1 - 0.00026 20.7 1.4 0.37 10.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EGD85192.1 - 0.00028 20.9 0.3 0.45 10.5 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EGD85192.1 - 0.00061 20.0 0.8 0.04 14.0 0.1 3.4 3 1 0 3 3 3 1 Helicase HerA, central domain AAA_7 PF12775.7 EGD85192.1 - 0.00072 19.1 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 EGD85192.1 - 0.00073 19.7 0.1 2.5 8.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain Rad17 PF03215.15 EGD85192.1 - 0.0013 18.7 0.1 0.0097 15.8 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 EGD85192.1 - 0.0041 17.7 0.1 0.64 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EGD85192.1 - 0.012 15.8 3.7 2.7 8.3 0.3 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 EGD85192.1 - 0.015 15.0 0.3 0.074 12.8 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 EGD85192.1 - 0.016 15.1 0.0 3.5 7.5 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 EGD85192.1 - 0.017 14.8 0.7 36 4.0 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_24 PF13479.6 EGD85192.1 - 0.021 14.5 0.2 0.7 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGD85192.1 - 0.021 14.8 0.2 18 5.4 0.0 4.1 5 0 0 5 5 5 0 AAA domain MMR_HSR1 PF01926.23 EGD85192.1 - 0.066 13.3 0.5 8.3 6.5 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGD85192.1 - 0.081 13.3 0.2 3.5 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 EGD85192.1 - 0.12 12.6 0.4 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EGD85192.1 - 0.13 12.0 0.1 4.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pkinase PF00069.25 EGD85194.2 - 1.1e-07 31.5 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85194.2 - 3.3e-05 23.3 0.0 0.00012 21.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGD85194.2 - 0.06 13.3 0.1 0.093 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGD85194.2 - 0.066 12.5 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SSXT PF05030.12 EGD85196.2 - 4.5e-05 23.0 8.5 0.0094 15.6 0.0 3.4 3 0 0 3 3 3 2 SSXT protein (N-terminal region) PDZ_1 PF12812.7 EGD85197.2 - 6.4e-41 138.2 0.0 8.8e-35 118.6 0.0 3.4 3 0 0 3 3 3 2 PDZ-like domain PDZ_6 PF17820.1 EGD85197.2 - 7.8e-12 44.9 2.5 3e-07 30.2 0.6 3.4 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EGD85197.2 - 1.4e-10 41.3 0.6 4.2e-05 23.8 0.1 3.1 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 EGD85197.2 - 5.6e-06 26.6 0.1 0.01 16.2 0.1 2.6 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EGD85197.2 - 0.0012 18.8 0.2 0.2 11.7 0.2 3.2 3 0 0 3 3 3 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 EGD85197.2 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal DNA_topoisoIV PF00521.20 EGD85199.2 - 7.4e-137 456.7 0.1 1.6e-136 455.6 0.1 1.6 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EGD85199.2 - 4.3e-52 175.7 6.7 4.3e-52 175.7 6.7 2.7 3 0 0 3 3 3 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EGD85199.2 - 1.6e-25 89.6 1.8 1.6e-25 89.6 1.8 2.1 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 EGD85199.2 - 3.4e-15 56.5 0.0 1e-14 54.9 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EGD85199.2 - 4.5e-07 30.0 0.0 3.2e-06 27.3 0.0 2.6 1 0 0 1 1 1 1 Toprim domain Reticulon PF02453.17 EGD85201.1 - 2.1e-27 96.0 5.8 2.9e-27 95.6 5.8 1.2 1 0 0 1 1 1 1 Reticulon Pex24p PF06398.11 EGD85201.1 - 0.0075 15.3 5.0 0.015 14.3 5.0 1.5 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Phasin_2 PF09361.10 EGD85201.1 - 0.039 14.2 1.9 0.1 12.9 0.6 2.1 2 0 0 2 2 2 0 Phasin protein SCAB_CC PF16712.5 EGD85201.1 - 0.15 11.9 0.2 0.26 11.1 0.2 1.3 1 1 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein CDC27 PF09507.10 EGD85201.1 - 0.2 11.0 6.8 0.3 10.4 6.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RabGAP-TBC PF00566.18 EGD85203.1 - 4.6e-49 167.0 0.6 2.1e-48 164.8 0.0 2.4 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF1664 PF07889.12 EGD85203.1 - 1.5 8.8 7.0 0.46 10.5 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 EGD85203.1 - 4.2 7.9 31.7 0.6 10.6 5.7 4.3 4 0 0 4 4 4 0 Apg6 coiled-coil region Sec2p PF06428.11 EGD85203.1 - 7.6 6.6 18.9 0.51 10.4 2.8 3.4 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p DUF2570 PF10828.8 EGD85203.1 - 7.9 6.4 13.4 2.1 8.2 2.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) EGF_2 PF07974.13 EGD85204.1 - 0.7 10.3 9.7 1.1 9.6 9.7 1.4 1 0 0 1 1 1 0 EGF-like domain MFS_1 PF07690.16 EGD85205.2 - 7e-29 100.8 29.9 9e-29 100.5 29.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EGD85205.2 - 0.0048 15.4 3.5 0.0058 15.1 3.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Med4 PF10018.9 EGD85206.1 - 1.9e-24 86.4 0.0 2.5e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 AIRC PF00731.20 EGD85206.1 - 0.087 12.4 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 AIR carboxylase DNA_pol_phi PF04931.13 EGD85206.1 - 0.12 10.4 0.9 0.15 10.1 0.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi EF-hand_1 PF00036.32 EGD85207.1 - 2.3e-26 89.3 9.6 2.7e-08 32.8 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EGD85207.1 - 1.5e-25 86.9 2.7 3e-06 26.7 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 EGD85207.1 - 1.7e-24 86.0 6.0 8.6e-16 58.2 0.6 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGD85207.1 - 1.1e-17 62.6 14.6 1.9e-05 24.0 0.0 4.8 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 EGD85207.1 - 3.2e-16 58.9 9.9 3.2e-06 26.9 0.9 4.2 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EGD85207.1 - 4.2e-09 36.3 4.6 0.001 19.0 0.1 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGD85207.1 - 8.7e-05 22.8 0.4 0.14 12.5 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGD85207.1 - 0.0033 17.7 0.9 0.52 10.7 0.2 3.1 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 EGD85207.1 - 0.016 14.1 0.5 1.2 7.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_10 PF14788.6 EGD85207.1 - 0.033 14.1 2.3 1.3 9.0 0.1 3.6 4 1 0 4 4 4 0 EF hand EMP70 PF02990.16 EGD85208.1 - 3.3e-193 643.1 3.7 4.4e-193 642.7 3.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 p450 PF00067.22 EGD85209.2 - 2e-43 148.8 0.0 3.2e-43 148.1 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.21 EGD85210.1 - 1.3e-31 110.1 0.0 1.6e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGD85210.1 - 0.00032 19.4 0.0 0.00048 18.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGD85210.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGD85210.1 - 0.002 17.5 0.1 0.027 13.8 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family SHMT PF00464.19 EGD85210.1 - 0.013 14.2 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase OKR_DC_1 PF01276.20 EGD85210.1 - 0.074 11.8 0.1 0.2 10.3 0.0 1.6 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain HNH_2 PF13391.6 EGD85212.1 - 3.2e-16 59.2 0.1 8.4e-16 57.9 0.1 1.8 1 0 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.16 EGD85213.1 - 4.5e-33 114.6 52.0 4.5e-33 114.6 52.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGD85213.1 - 2.9e-20 72.2 17.8 3.5e-20 72.0 17.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGD85213.1 - 3.8e-13 49.1 8.8 3.8e-13 49.1 8.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EGD85213.1 - 1.4 7.1 11.3 0.95 7.7 3.5 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Transferase PF02458.15 EGD85214.2 - 0.058 12.0 0.0 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 Transferase family Pkinase PF00069.25 EGD85222.2 - 1e-17 64.4 0.1 9.4e-17 61.2 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85222.2 - 5e-06 26.0 0.0 0.057 12.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase NmrA PF05368.13 EGD85223.1 - 5.6e-38 130.8 0.0 8.8e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGD85223.1 - 1.8e-12 47.5 0.0 2.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EGD85223.1 - 0.0034 17.8 0.0 0.006 17.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EGD85223.1 - 0.029 13.8 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FMO-like PF00743.19 EGD85224.1 - 3.8e-15 55.3 0.0 8.4e-15 54.2 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGD85224.1 - 1e-13 51.2 0.0 4.5e-10 39.3 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGD85224.1 - 3.6e-12 46.1 0.0 1.9e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGD85224.1 - 1.7e-10 40.6 0.0 4.2e-08 32.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGD85224.1 - 5.5e-07 29.7 1.0 2.3e-05 24.6 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGD85224.1 - 2.3e-06 28.0 2.2 0.042 14.4 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGD85224.1 - 5.4e-06 25.9 0.1 0.0052 16.1 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EGD85224.1 - 0.00038 20.5 1.5 0.07 13.1 0.0 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 EGD85224.1 - 0.0012 18.5 2.5 0.012 15.2 0.5 3.0 2 1 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EGD85224.1 - 0.0063 16.9 0.0 0.077 13.4 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 EGD85224.1 - 0.0068 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EGD85224.1 - 0.015 15.4 0.1 5.2 7.1 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EGD85224.1 - 0.028 13.5 0.2 0.028 13.5 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EGD85224.1 - 0.13 11.0 1.0 1.2 7.8 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein FAD_oxidored PF12831.7 EGD85224.1 - 0.51 9.6 1.2 1.5 8.0 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EGD85224.1 - 7.3 5.5 5.9 0.97 8.4 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Sas10_Utp3 PF04000.15 EGD85226.1 - 1.9e-18 66.9 1.6 6.3e-18 65.2 1.6 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Glypican PF01153.19 EGD85226.1 - 0.3 9.9 2.2 0.49 9.2 2.2 1.3 1 0 0 1 1 1 0 Glypican MFS_1 PF07690.16 EGD85227.1 - 2.3e-11 43.3 40.2 2.3e-11 43.3 40.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGD85227.1 - 5.9e-08 32.6 7.2 5.9e-08 32.6 7.2 2.9 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Amidoligase_2 PF12224.8 EGD85229.1 - 5.5e-10 39.3 0.0 3e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Putative amidoligase enzyme APH PF01636.23 EGD85230.1 - 2e-13 50.9 0.0 4.6e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGD85230.1 - 0.019 13.8 0.0 2 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) CFEM PF05730.11 EGD85231.1 - 5.3e-15 55.3 5.5 7.5e-15 54.8 5.5 1.2 1 0 0 1 1 1 1 CFEM domain UQ_con PF00179.26 EGD85232.1 - 1.8e-44 150.8 0.0 2e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGD85232.1 - 0.14 11.9 0.1 0.24 11.1 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 EGD85232.1 - 0.32 11.3 2.3 0.42 10.9 2.3 1.6 1 1 0 1 1 1 0 RWD domain IBV_3C PF03620.13 EGD85233.1 - 0.12 12.9 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 IBV 3C protein AA_permease PF00324.21 EGD85234.2 - 6.2e-64 216.3 25.6 2.6e-63 214.3 25.6 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD85234.2 - 3e-24 85.6 19.1 3e-24 85.6 19.1 1.5 1 1 1 2 2 2 1 Amino acid permease 7tm_1 PF00001.21 EGD85234.2 - 0.15 11.4 6.7 0.15 11.4 0.0 3.1 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) TspO_MBR PF03073.15 EGD85234.2 - 0.82 9.7 10.0 0.23 11.5 5.4 2.6 2 1 0 2 2 2 0 TspO/MBR family LtrA PF06772.11 EGD85235.2 - 5.8e-24 85.0 26.9 5.8e-24 85.0 26.9 2.0 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) DUF2976 PF11190.8 EGD85235.2 - 0.038 13.8 0.2 0.038 13.8 0.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2976) FerA PF08165.11 EGD85235.2 - 0.08 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 FerA (NUC095) domain DUF3188 PF11384.8 EGD85235.2 - 0.12 12.1 0.9 0.46 10.2 0.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) DUF4212 PF13937.6 EGD85235.2 - 7.4 7.0 13.8 1.2 9.6 1.0 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4212) Mito_carr PF00153.27 EGD85236.2 - 1.3e-55 185.2 5.2 5.4e-19 67.9 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIIC_delta PF12657.7 EGD85237.1 - 1.2e-43 149.2 0.2 2.9e-43 148.0 0.2 1.7 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 EGD85237.1 - 7.9e-30 102.8 1.5 1.6e-29 101.9 1.5 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Glyco_trans_4_4 PF13579.6 EGD85238.1 - 5.3e-09 36.7 0.5 8.6e-09 36.0 0.5 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EGD85238.1 - 2.1e-06 27.9 1.4 3.3e-06 27.2 1.4 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EGD85238.1 - 4.6e-06 27.1 0.0 2.6e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGD85238.1 - 0.0015 18.1 0.0 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGD85238.1 - 0.026 14.9 0.0 0.066 13.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 AveC_like PF17198.4 EGD85239.2 - 0.00075 19.0 1.1 0.0018 17.8 0.3 2.0 1 1 1 2 2 2 1 Spirocyclase AveC-like DUF2070 PF09843.9 EGD85239.2 - 1.5 7.0 13.5 0.45 8.7 10.3 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) UQ_con PF00179.26 EGD85240.1 - 1.3e-51 173.9 0.0 1.5e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGD85240.1 - 0.0007 19.3 0.0 0.00078 19.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGD85240.1 - 0.083 13.2 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 RWD domain Helicase_C PF00271.31 EGD85243.2 - 6.8e-07 29.6 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Asp_protease_2 PF13650.6 EGD85244.1 - 0.079 13.6 0.2 0.14 12.8 0.2 1.4 1 0 0 1 1 1 0 Aspartyl protease Thiolase_N PF00108.23 EGD85245.1 - 2.1e-92 309.2 1.4 2.8e-92 308.8 1.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGD85245.1 - 2.1e-37 127.5 0.6 2.1e-37 127.5 0.6 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGD85245.1 - 9.3e-05 22.1 0.4 0.00021 20.9 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGD85245.1 - 0.014 15.2 2.6 2.4 8.0 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Kinesin PF00225.23 EGD85246.2 - 4e-104 348.1 0.8 4e-104 348.1 0.8 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGD85246.2 - 6.9e-18 65.0 0.0 3e-17 62.9 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding DUF1398 PF07166.11 EGD85246.2 - 0.036 14.1 0.2 0.13 12.4 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) LEA_6 PF10714.9 EGD85246.2 - 0.12 12.4 1.1 0.33 11.1 1.1 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 NPV_P10 PF05531.12 EGD85246.2 - 0.27 11.7 0.1 0.27 11.7 0.1 6.5 5 2 2 7 7 7 0 Nucleopolyhedrovirus P10 protein XkdW PF09636.10 EGD85246.2 - 2.3 8.4 12.1 6.2 7.0 4.3 3.3 2 0 0 2 2 2 0 XkdW protein Nbl1_Borealin_N PF10444.9 EGD85246.2 - 3.5 7.3 11.3 0.76 9.5 0.4 4.4 3 1 0 3 3 3 0 Nbl1 / Borealin N terminal 5_nucleotid_C PF02872.18 EGD85248.1 - 3.8e-37 127.9 0.0 5.9e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGD85248.1 - 1.7e-06 28.7 0.0 3.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UPF0160 PF03690.13 EGD85249.1 - 4.7e-124 414.2 0.0 5.3e-124 414.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Trimer_CC PF08954.11 EGD85249.1 - 0.0094 15.5 0.1 0.43 10.2 0.0 2.4 2 0 0 2 2 2 1 Trimerisation motif Peptidase_M35 PF02102.15 EGD85252.1 - 8.4e-104 347.3 8.9 1e-103 347.0 8.9 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EGD85252.1 - 9.4e-46 156.0 3.1 2e-45 154.9 3.1 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EGD85252.1 - 7e-06 25.8 5.3 8e-05 22.3 5.3 2.0 1 1 0 1 1 1 1 Putative peptidase family His_Phos_1 PF00300.22 EGD85253.1 - 0.0004 20.1 2.6 1.9 8.1 0.0 4.0 3 1 1 4 4 4 3 Histidine phosphatase superfamily (branch 1) DUF4980 PF16352.5 EGD85255.1 - 0.063 13.3 0.0 0.081 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4980) MFS_1 PF07690.16 EGD85256.1 - 1.1e-20 73.8 61.3 4e-12 45.7 20.4 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Fungal_trans PF04082.18 EGD85257.2 - 3.8e-07 29.4 0.0 1.6e-06 27.3 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.14 EGD85258.2 - 6.9e-21 74.7 0.0 9.6e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGD85258.2 - 3.4e-12 46.7 0.0 6.5e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGD85258.2 - 7.4e-07 28.6 0.1 4e-06 26.2 0.1 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EGD85258.2 - 0.0005 19.4 0.0 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Eno-Rase_NADH_b PF12242.8 EGD85258.2 - 0.0024 17.6 0.5 0.25 11.1 0.0 3.0 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Lycopene_cycl PF05834.12 EGD85258.2 - 0.0092 15.1 0.0 3.5 6.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 EGD85258.2 - 0.085 12.4 0.0 0.81 9.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGD85258.2 - 0.15 10.9 0.0 1.1 8.1 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Pkinase PF00069.25 EGD85259.2 - 1.8e-10 40.7 0.3 1.1e-09 38.1 0.3 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85259.2 - 1.6e-05 24.4 0.2 3.4e-05 23.3 0.3 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGD85259.2 - 5.2e-05 22.7 0.2 8.5e-05 22.0 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGD85259.2 - 0.00088 18.9 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EGD85259.2 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGD85259.2 - 0.015 14.9 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGD85259.2 - 0.036 14.0 0.4 0.066 13.1 0.4 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGD85259.2 - 0.11 11.3 0.2 0.16 10.7 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EGD85263.2 - 9.8e-15 54.6 0.0 1.7e-14 53.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85263.2 - 2.7e-10 40.0 0.0 1.3e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EGD85263.2 - 0.058 12.9 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CytB6-F_Fe-S PF08802.10 EGD85264.2 - 0.17 11.9 1.3 0.33 11.0 1.3 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit HNH_2 PF13391.6 EGD85265.1 - 0.00045 20.3 0.2 0.0017 18.5 0.1 2.0 2 0 0 2 2 2 1 HNH endonuclease Methyltransf_25 PF13649.6 EGD85268.1 - 1.2e-16 61.2 0.0 4.3e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD85268.1 - 1.4e-14 54.5 0.0 2.5e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD85268.1 - 2.3e-13 50.2 0.0 3e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD85268.1 - 4e-12 46.7 0.0 6.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD85268.1 - 6.3e-12 45.6 0.0 8.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD85268.1 - 1.6e-06 27.6 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 EGD85268.1 - 2.3e-06 26.8 0.0 3.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 EGD85268.1 - 2.4e-06 27.5 0.0 5.1e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EGD85268.1 - 3.5e-05 23.4 0.0 5.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EGD85268.1 - 0.00044 19.6 0.0 0.0006 19.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 EGD85268.1 - 0.00045 19.9 0.0 0.00065 19.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 EGD85268.1 - 0.014 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EGD85268.1 - 0.043 13.8 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EGD85268.1 - 0.055 12.5 0.0 0.077 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.12 EGD85268.1 - 0.089 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DREV PF05219.12 EGD85268.1 - 0.21 10.6 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase M16C_assoc PF08367.11 EGD85269.2 - 3e-74 249.3 0.3 4.9e-74 248.6 0.3 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EGD85269.2 - 4.9e-25 88.6 0.0 3.7e-16 59.7 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGD85269.2 - 3.5e-10 40.0 0.0 1.8e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DinB_2 PF12867.7 EGD85269.2 - 0.12 12.9 0.2 2.6 8.6 0.0 2.7 2 0 0 2 2 2 0 DinB superfamily Taxilin PF09728.9 EGD85270.2 - 2.8e-88 296.0 51.1 3.3e-88 295.8 51.1 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein APG6_N PF17675.1 EGD85270.2 - 0.015 15.8 9.5 0.015 15.8 9.5 3.8 2 1 1 3 3 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 EGD85270.2 - 0.076 12.3 35.6 0.15 11.4 7.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 EGD85270.2 - 0.094 12.9 42.1 0.32 11.2 12.1 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding OmpH PF03938.14 EGD85270.2 - 0.23 11.8 38.7 0.029 14.7 5.5 3.3 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF3675 PF12428.8 EGD85270.2 - 0.39 11.3 2.9 7 7.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) UPF0242 PF06785.11 EGD85270.2 - 0.59 10.2 47.9 0.59 10.2 8.4 4.0 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus COG2 PF06148.11 EGD85270.2 - 0.6 10.2 18.4 1.1 9.4 0.7 3.1 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 EGD85270.2 - 1.1 8.4 33.2 0.69 9.1 6.9 3.0 2 1 1 3 3 3 0 TMPIT-like protein zf-C4H2 PF10146.9 EGD85270.2 - 2 8.7 27.4 0.15 12.3 8.9 2.8 2 1 0 2 2 2 0 Zinc finger-containing protein DUF3584 PF12128.8 EGD85270.2 - 2.7 5.4 43.7 2 5.8 40.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) BRE1 PF08647.11 EGD85270.2 - 2.9 8.0 45.4 4.9 7.3 14.7 4.0 3 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase DUF4559 PF15112.6 EGD85270.2 - 5.8 6.5 26.0 0.061 13.0 9.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) ERM PF00769.19 EGD85270.2 - 6.3 6.5 51.1 0.19 11.5 19.9 3.1 1 1 1 3 3 3 0 Ezrin/radixin/moesin family NMO PF03060.15 EGD85271.1 - 1.5e-53 182.3 0.4 2e-53 182.0 0.4 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGD85271.1 - 1.2e-06 27.8 0.3 2.5e-05 23.4 0.3 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGD85271.1 - 0.0022 17.1 3.2 0.0037 16.4 3.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PEP_hydrolase PF09370.10 EGD85271.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Baculo_Y142 PF04913.12 EGD85272.2 - 0.033 12.9 0.0 0.036 12.8 0.0 1.0 1 0 0 1 1 1 0 Baculovirus Y142 protein FeoB_associated PF12669.7 EGD85272.2 - 0.2 12.1 0.5 0.76 10.2 0.0 2.0 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DNA_pol_E_B PF04042.16 EGD85273.2 - 4.5e-44 150.3 0.0 1.1e-43 149.1 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EGD85273.2 - 3.1e-37 127.6 0.0 5.2e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Acetyltransf_3 PF13302.7 EGD85274.1 - 1.1e-25 90.9 0.0 4.5e-25 88.9 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD85274.1 - 0.0007 19.5 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_4 PF13420.7 EGD85274.1 - 0.0029 17.8 0.3 0.018 15.2 0.0 2.4 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGD85274.1 - 0.0054 16.4 2.5 1.3 8.7 0.5 3.4 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain Ribosomal_L38e PF01781.18 EGD85275.1 - 1.1e-31 108.7 1.9 1.3e-31 108.5 1.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Ish1 PF10281.9 EGD85276.1 - 1.8e-06 28.1 0.1 2.8e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein LnmK_N_HDF PF18238.1 EGD85276.1 - 0.18 11.6 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 LnmK N-terminal Hot Dog Fold domain NTF2 PF02136.20 EGD85277.1 - 2.1e-09 38.0 0.1 3.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EGD85277.1 - 0.0024 17.8 0.1 0.0035 17.3 0.1 1.4 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 tRNA-synt_1g PF09334.11 EGD85278.2 - 8.6e-48 163.0 0.0 1.2e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGD85278.2 - 2.4e-12 45.9 0.0 3.8e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGD85278.2 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGD85278.2 - 0.012 15.0 0.0 0.032 13.6 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain PALP PF00291.25 EGD85280.2 - 5.1e-25 88.5 0.3 2.9e-22 79.5 0.1 2.7 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme PPTA PF01239.22 EGD85281.1 - 7.7e-36 120.8 17.5 2.1e-09 36.8 2.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.6 EGD85281.1 - 0.0021 18.7 8.6 0.004 17.8 2.7 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGD85281.1 - 0.039 14.8 0.9 0.039 14.8 0.9 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGD85281.1 - 0.21 12.0 1.3 0.89 10.1 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat AA_permease PF00324.21 EGD85283.2 - 8.4e-54 182.9 32.0 1e-53 182.6 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EGD85283.2 - 1.3e-22 80.5 0.1 8.4e-07 28.4 0.0 3.4 3 0 0 3 3 3 3 Solute carrier family 12 Aa_trans PF01490.18 EGD85284.1 - 4.1e-85 286.0 35.6 4.9e-85 285.7 35.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TM_PBP2_N PF16296.5 EGD85284.1 - 0.025 14.7 0.0 0.07 13.3 0.0 1.8 1 0 0 1 1 1 0 N-terminal of TM subunit in PBP-dependent ABC transporters Glycophorin_A PF01102.18 EGD85284.1 - 0.079 13.2 2.0 1.5 9.1 0.1 2.7 2 0 0 2 2 2 0 Glycophorin A MPC PF03650.13 EGD85285.1 - 3.3e-35 120.5 0.1 4e-35 120.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers LSM PF01423.22 EGD85286.1 - 6.4e-19 67.4 0.0 8e-19 67.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.21 EGD85287.2 - 3.4e-22 78.4 0.0 4.9e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGD85287.2 - 2e-20 72.8 0.0 7.6e-20 71.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 CPSase_L_D2 PF02786.17 EGD85289.1 - 1.3e-80 269.9 0.1 2.1e-80 269.2 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EGD85289.1 - 2.7e-69 232.9 0.0 4.6e-69 232.2 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EGD85289.1 - 1.4e-39 135.0 0.1 2.9e-39 134.0 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGD85289.1 - 5.7e-31 106.8 0.0 1.9e-30 105.1 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EGD85289.1 - 8.9e-23 81.2 0.0 1.9e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EGD85289.1 - 4.3e-17 61.7 4.5 4.6e-17 61.6 2.9 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGD85289.1 - 5.6e-09 35.7 1.9 0.0001 22.1 0.1 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EGD85289.1 - 8e-09 35.3 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGD85289.1 - 5.9e-07 29.2 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGD85289.1 - 0.00011 22.2 0.0 0.00029 20.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EGD85289.1 - 0.00047 19.8 0.0 0.00098 18.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 EGD85289.1 - 0.0013 18.0 0.1 0.07 12.3 0.1 2.5 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EGD85289.1 - 0.019 15.6 0.1 7.6 7.3 0.1 3.1 3 0 0 3 3 3 0 HlyD family secretion protein ATP-grasp_4 PF13535.6 EGD85289.1 - 0.024 14.3 0.0 0.36 10.4 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain DUF2118 PF09891.9 EGD85289.1 - 0.037 14.0 0.1 0.089 12.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Clathrin PF00637.20 EGD85291.2 - 2.2e-194 637.1 35.5 1.4e-32 112.5 0.2 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EGD85291.2 - 1.1e-33 113.9 5.5 1.4e-05 25.1 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 EGD85291.2 - 5.4e-30 103.1 1.4 1.8e-29 101.5 0.2 2.6 2 1 0 2 2 2 1 Clathrin-H-link TPR_14 PF13428.6 EGD85291.2 - 2.3e-06 27.9 4.9 0.31 12.0 0.2 7.7 9 0 0 9 9 7 1 Tetratricopeptide repeat Clathrin-link PF09268.10 EGD85291.2 - 0.0086 15.4 0.0 0.019 14.3 0.0 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_7 PF13176.6 EGD85291.2 - 0.025 14.6 5.5 68 3.8 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGD85291.2 - 0.12 12.7 5.9 2.8 8.4 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EGD85291.2 - 0.17 10.9 6.5 1.7 7.6 0.3 3.4 3 0 0 3 3 3 0 Coatomer WD associated region DUF1400 PF07176.11 EGD85291.2 - 0.78 10.0 4.0 10 6.4 0.0 4.3 4 1 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) TPR_1 PF00515.28 EGD85291.2 - 0.94 9.4 4.4 32 4.6 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGD85291.2 - 1.3 9.6 8.6 50 4.5 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat INSIG PF07281.12 EGD85292.1 - 7e-74 248.0 5.6 1.1e-73 247.4 5.6 1.3 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) DEAD PF00270.29 EGD85294.1 - 7.7e-48 162.6 0.0 3e-47 160.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD85294.1 - 3.4e-32 111.1 0.0 7.6e-32 110.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD85294.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGD85294.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 EGD85294.1 - 0.22 10.7 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Fungal_trans_2 PF11951.8 EGD85295.1 - 1.3e-06 27.5 0.1 1.1e-05 24.4 0.0 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain DUF639 PF04842.12 EGD85295.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) COesterase PF00135.28 EGD85298.1 - 1.2e-98 331.3 0.0 1.5e-98 330.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGD85298.1 - 6.5e-05 22.9 0.1 0.00016 21.6 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGD85298.1 - 0.0085 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Rad9_Rad53_bind PF08605.10 EGD85298.1 - 0.22 11.7 0.0 1.4 9.1 0.0 2.0 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding Pro_isomerase PF00160.21 EGD85299.1 - 1.9e-49 168.0 0.4 2.5e-49 167.6 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 EGD85300.1 - 6e-17 62.2 0.1 7.8e-15 55.4 0.1 2.2 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EGD85300.1 - 0.032 13.0 0.0 0.05 12.4 0.0 1.4 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Zw10 PF06248.13 EGD85302.1 - 1.1e-07 30.9 4.9 2.2e-07 29.8 4.9 1.5 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 EGD85302.1 - 1.5e-06 28.0 0.0 3.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal IFT46_B_C PF12317.8 EGD85302.1 - 0.12 12.1 2.1 0.26 11.0 2.1 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal ArAE_1_C PF11728.8 EGD85302.1 - 0.15 12.1 5.9 0.32 11.0 5.9 1.5 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain Fib_alpha PF08702.10 EGD85302.1 - 0.2 11.9 3.2 1 9.5 2.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family KELK PF15796.5 EGD85302.1 - 0.98 9.9 6.0 2.7 8.5 6.0 1.8 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase APC_u15 PF16636.5 EGD85302.1 - 2 8.9 10.6 6.9 7.2 1.0 2.9 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 DivIC PF04977.15 EGD85302.1 - 5.4 6.9 6.1 63 3.4 0.1 2.8 2 0 0 2 2 2 0 Septum formation initiator RQC PF09382.10 EGD85303.2 - 0.076 12.8 0.4 3.5 7.4 0.1 2.6 2 0 0 2 2 2 0 RQC domain M16C_assoc PF08367.11 EGD85303.2 - 0.094 11.8 3.0 1.7 7.7 0.0 2.5 3 0 0 3 3 3 0 Peptidase M16C associated Ank_2 PF12796.7 EGD85304.2 - 1.5e-57 192.1 0.2 1.2e-14 54.6 0.0 6.3 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD85304.2 - 2.4e-44 149.2 0.2 1.5e-09 38.2 0.1 8.4 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD85304.2 - 3.6e-37 122.2 0.1 0.0065 16.9 0.0 11.6 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 EGD85304.2 - 2.5e-27 94.6 1.0 5.4e-05 23.4 0.2 8.6 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 EGD85304.2 - 2.6e-27 94.0 1.6 0.033 14.6 0.1 10.8 11 0 0 11 11 11 6 Ankyrin repeat NACHT PF05729.12 EGD85304.2 - 0.016 15.1 0.0 0.043 13.7 0.0 1.8 1 0 0 1 1 1 0 NACHT domain DUF3710 PF12502.8 EGD85304.2 - 0.064 12.9 0.1 13 5.4 0.0 3.0 1 1 0 3 3 3 0 Protein of unknown function (DUF3710) DUF1843 PF08898.10 EGD85304.2 - 5.9 7.5 6.4 20 5.8 0.1 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) MFS_1 PF07690.16 EGD85307.1 - 1.5e-10 40.5 9.1 1.7e-10 40.4 9.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_2 PF00891.18 EGD85308.1 - 3.4e-22 78.8 0.0 4.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EGD85308.1 - 0.00034 21.3 0.0 0.00067 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD85308.1 - 0.00083 19.2 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD85308.1 - 0.0017 19.0 0.0 0.0026 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EGD85308.1 - 0.025 14.1 0.1 0.05 13.1 0.0 1.5 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain DUF608 PF04685.13 EGD85308.1 - 0.031 13.5 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region NAS PF03059.16 EGD85308.1 - 0.068 12.5 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein Methyltransf_31 PF13847.6 EGD85308.1 - 0.17 11.7 0.0 0.46 10.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_M48_N PF16491.5 EGD85309.1 - 2.9e-66 222.9 8.8 2.9e-66 222.9 8.8 1.6 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EGD85309.1 - 9.2e-45 152.8 0.0 1.8e-44 151.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.6 EGD85309.1 - 0.01 15.5 1.1 0.03 14.1 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Peptidase_M56 PF05569.11 EGD85309.1 - 0.03 13.5 2.2 0.12 11.6 0.6 2.2 2 1 0 2 2 2 0 BlaR1 peptidase M56 PGA2 PF07543.12 EGD85310.1 - 0.13 12.2 10.8 0.18 11.8 10.8 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Peptidase_S49_N PF08496.10 EGD85310.1 - 2.6 8.1 7.8 2.3 8.2 6.7 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ribosomal_L34 PF00468.17 EGD85311.1 - 8.9e-16 57.6 9.5 1.4e-15 57.0 9.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 eIF2_C PF09173.11 EGD85312.1 - 2.9e-34 117.2 0.2 7.2e-34 115.9 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EGD85312.1 - 6.1e-23 81.4 0.2 4.5e-22 78.6 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGD85312.1 - 8.7e-12 45.3 0.2 1.9e-11 44.2 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EGD85312.1 - 0.0056 16.6 0.1 0.063 13.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EGD85312.1 - 0.0063 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase WD40 PF00400.32 EGD85313.1 - 4.9e-09 36.7 0.0 3.5 8.7 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EGD85313.1 - 0.00085 18.2 0.0 0.63 8.7 0.0 2.2 2 0 0 2 2 2 2 Nup133 N terminal like CW_7 PF08230.11 EGD85313.1 - 0.014 15.1 0.2 0.03 14.1 0.2 1.4 1 0 0 1 1 1 0 CW_7 repeat Myb_DNA-bind_6 PF13921.6 EGD85314.1 - 6.5e-17 61.5 0.1 6.5e-17 61.5 0.1 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain HSA PF07529.13 EGD85314.1 - 7.3e-14 51.9 0.3 7.3e-14 51.9 0.3 3.3 3 0 0 3 3 3 1 HSA Myb_DNA-binding PF00249.31 EGD85314.1 - 0.00021 21.4 0.4 0.00057 20.0 0.4 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain G-patch_2 PF12656.7 EGD85315.2 - 1.9e-24 85.5 0.2 6.9e-24 83.7 0.2 2.1 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 EGD85315.2 - 0.0003 20.6 0.6 0.0013 18.6 0.6 2.1 1 0 0 1 1 1 1 G-patch domain WD40 PF00400.32 EGD85316.1 - 2.6e-57 189.4 12.5 1e-05 26.2 0.0 14.1 13 3 0 13 13 13 9 WD domain, G-beta repeat Utp13 PF08625.11 EGD85316.1 - 1.2e-47 161.4 0.2 2.1e-47 160.6 0.2 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EGD85316.1 - 1.2e-12 47.9 1.7 2.8 8.3 0.0 8.7 5 2 4 10 10 10 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD85316.1 - 3e-05 22.9 7.7 1.4 7.5 1.4 5.2 4 2 1 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGD85316.1 - 0.00034 19.5 3.0 0.8 8.4 0.1 4.5 4 1 1 6 6 6 2 Nup133 N terminal like Ge1_WD40 PF16529.5 EGD85316.1 - 0.00075 18.5 1.8 3.1 6.6 0.0 5.1 3 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein UCH PF00443.29 EGD85318.1 - 9.3e-22 77.7 0.0 3.4e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGD85318.1 - 4.4e-12 46.1 0.3 7.8e-12 45.4 0.3 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGD85318.1 - 0.0032 17.1 0.1 0.012 15.3 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TLD PF07534.16 EGD85319.1 - 1.8e-12 47.7 0.0 3.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 TLD MF_alpha_N PF05436.11 EGD85320.1 - 0.012 15.5 0.8 0.021 14.7 0.3 1.7 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus Peptidase_C97 PF05903.14 EGD85320.1 - 0.027 14.3 0.2 0.051 13.4 0.1 1.5 2 0 0 2 2 2 0 PPPDE putative peptidase domain Proteasome PF00227.26 EGD85321.1 - 1.9e-29 102.5 0.0 2.1e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.32 EGD85322.1 - 5.6e-19 68.1 11.3 2e-05 25.2 0.0 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD85322.1 - 0.00066 19.9 0.0 0.015 15.6 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGD85322.1 - 0.0072 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain ARF7EP_C PF14949.6 EGD85323.2 - 6 7.5 6.1 0.71 10.5 0.8 2.2 2 1 0 2 2 2 0 ARF7 effector protein C-terminus CDC45 PF02724.14 EGD85323.2 - 7.2 4.8 9.4 9.5 4.4 9.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2527 PF10736.9 EGD85324.1 - 0.02 14.7 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) CHCH PF06747.13 EGD85325.2 - 2.4e-05 24.3 3.8 4.9e-05 23.3 3.7 1.6 1 1 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 EGD85325.2 - 0.013 15.7 1.0 0.02 15.1 1.0 1.2 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type COX17 PF05051.13 EGD85325.2 - 0.37 11.2 4.3 0.98 9.8 2.4 2.3 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) Proteasome PF00227.26 EGD85327.2 - 1.2e-41 142.3 0.0 1.5e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.8 EGD85328.1 - 1.9e-24 85.7 1.0 3.1e-24 85.0 0.1 1.9 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 EGD85328.1 - 7.1e-06 26.1 0.2 6e-05 23.2 0.0 2.6 4 0 0 4 4 4 1 UBX domain RBD PF02196.15 EGD85328.1 - 0.0089 16.1 0.0 0.061 13.4 0.0 2.2 2 0 0 2 2 2 1 Raf-like Ras-binding domain Ribosomal_L36e PF01158.18 EGD85329.1 - 2.3e-38 130.3 7.0 2.6e-38 130.2 7.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e HTH_38 PF13936.6 EGD85329.1 - 0.0083 15.9 1.9 0.22 11.3 0.1 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain PBS_linker_poly PF00427.21 EGD85329.1 - 0.039 14.0 0.4 0.044 13.8 0.4 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide MRP-L28 PF09812.9 EGD85329.1 - 0.12 12.5 2.6 0.14 12.3 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF2207 PF09972.9 EGD85329.1 - 0.13 11.0 0.2 0.14 10.9 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4239 PF14023.6 EGD85329.1 - 0.14 11.9 0.1 0.18 11.5 0.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) HATPase_c PF02518.26 EGD85330.1 - 7.9e-19 68.2 0.0 2.5e-18 66.6 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGD85330.1 - 9.9e-15 54.7 0.4 4.6e-09 36.4 0.0 3.4 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 EGD85330.1 - 6.4e-05 22.9 0.1 0.00027 20.9 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGD85330.1 - 0.059 13.2 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase M20_dimer PF07687.14 EGD85331.1 - 3.1e-20 72.1 0.0 7.4e-20 70.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EGD85331.1 - 1.7e-15 57.3 0.2 5.6e-14 52.3 0.2 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EGD85331.1 - 0.00077 18.6 0.0 0.0074 15.3 0.0 2.3 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase DUF373 PF04123.13 EGD85331.1 - 0.01 15.3 0.2 0.017 14.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Peptidase_M28 PF04389.17 EGD85331.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Glyco_hydro_47 PF01532.20 EGD85332.2 - 1.4e-157 525.3 0.0 1.7e-157 525.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA PF00004.29 EGD85333.1 - 7.2e-43 146.2 0.0 1.2e-42 145.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGD85333.1 - 3.4e-11 42.9 0.0 9.5e-11 41.5 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGD85333.1 - 1.6e-10 40.6 0.1 3e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGD85333.1 - 2.8e-07 31.1 0.0 0.00012 22.5 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGD85333.1 - 1.8e-06 28.0 0.0 4.3e-05 23.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGD85333.1 - 2.5e-06 27.7 0.0 8e-06 26.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGD85333.1 - 6.9e-06 25.9 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGD85333.1 - 0.00019 21.8 0.0 0.0031 17.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGD85333.1 - 0.00046 19.4 0.0 0.00096 18.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EGD85333.1 - 0.00051 20.6 0.1 0.0033 18.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGD85333.1 - 0.00056 19.5 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EGD85333.1 - 0.0019 17.5 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGD85333.1 - 0.0039 17.3 0.0 0.0095 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 EGD85333.1 - 0.0041 16.7 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 EGD85333.1 - 0.0048 16.3 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGD85333.1 - 0.0052 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EGD85333.1 - 0.0073 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGD85333.1 - 0.0074 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 EGD85333.1 - 0.0091 15.7 0.0 0.03 14.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 EGD85333.1 - 0.0093 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGD85333.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 EGD85333.1 - 0.032 13.6 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 EGD85333.1 - 0.034 13.9 0.0 0.087 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGD85333.1 - 0.073 13.0 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EGD85333.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 EGD85333.1 - 0.097 12.4 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGD85333.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EGD85333.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGD85333.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 EGD85333.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGD85333.1 - 0.13 12.0 0.1 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Cation_ATPase_C PF00689.21 EGD85334.1 - 8.9e-44 149.4 4.2 8.9e-44 149.4 4.2 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGD85334.1 - 7.3e-38 129.9 5.3 9.9e-38 129.5 1.3 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGD85334.1 - 1.2e-20 74.7 0.0 9.3e-09 35.9 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGD85334.1 - 4.1e-19 68.5 0.0 8.3e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGD85334.1 - 7.1e-11 41.6 0.0 1.5e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGD85334.1 - 0.00064 19.5 0.3 0.0019 18.0 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGD85334.1 - 0.00087 19.7 0.0 0.24 11.8 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 EGD85334.1 - 1.7 8.4 5.2 7.3 6.4 0.6 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) Wzy_C PF04932.15 EGD85334.1 - 7.4 6.2 6.2 12 5.5 0.2 3.2 3 0 0 3 3 3 0 O-Antigen ligase Enolase_C PF00113.22 EGD85337.1 - 2.2e-154 513.0 0.0 2.8e-154 512.7 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGD85337.1 - 3.2e-56 189.1 0.2 5.5e-56 188.3 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGD85337.1 - 8.8e-06 25.4 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like VSP PF03302.13 EGD85337.1 - 0.14 11.0 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein eIF3_subunit PF08597.10 EGD85338.2 - 4.8e-65 219.9 30.8 5.9e-65 219.6 30.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF572 PF04502.13 EGD85338.2 - 0.051 13.2 21.0 0.068 12.8 21.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4746 PF15928.5 EGD85338.2 - 2 7.8 12.6 1.6 8.1 9.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) GREB1 PF15782.5 EGD85338.2 - 3.8 4.5 8.0 4.4 4.3 8.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pap_E4 PF02711.14 EGD85338.2 - 5.4 8.1 12.0 1.7 9.7 0.1 3.0 3 1 1 4 4 4 0 E4 protein 14-3-3 PF00244.20 EGD85339.1 - 6.5e-107 356.1 3.6 8e-107 355.8 3.6 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF4164 PF13747.6 EGD85339.1 - 0.12 12.7 2.0 0.41 11.0 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Peptidase_C98 PF15499.6 EGD85339.1 - 0.16 11.4 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ima1_N PF09779.9 EGD85339.1 - 0.32 11.8 3.1 2.1 9.2 0.0 3.2 4 0 0 4 4 4 0 Ima1 N-terminal domain adh_short PF00106.25 EGD85340.1 - 8.7e-21 74.3 0.0 1.4e-17 63.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGD85340.1 - 3e-10 40.1 0.0 5.2e-09 36.0 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD85340.1 - 8.2e-06 25.8 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 KR domain E1-E2_ATPase PF00122.20 EGD85341.2 - 9e-50 168.7 9.0 4.4e-49 166.4 1.9 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGD85341.2 - 2.1e-47 161.2 7.4 2.1e-47 161.2 7.4 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGD85341.2 - 8.7e-22 78.4 0.2 3.3e-21 76.6 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGD85341.2 - 3.5e-16 59.0 0.0 7.1e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGD85341.2 - 4.3e-08 33.2 1.2 8.4e-06 25.7 0.9 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGD85341.2 - 2.3e-06 27.2 0.4 7.6e-06 25.5 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 EGD85341.2 - 3e-06 27.8 0.0 1.1e-05 26.0 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_S8 PF00082.22 EGD85342.1 - 5.3e-31 108.0 17.3 1e-30 107.0 17.3 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGD85342.1 - 9.8e-16 58.2 0.4 1.7e-15 57.4 0.4 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 MBOAT_2 PF13813.6 EGD85344.2 - 1.2e-18 67.2 4.4 3.3e-18 65.7 4.4 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family FAM76 PF16046.5 EGD85345.1 - 1.7 7.9 3.6 2.1 7.6 3.6 1.1 1 0 0 1 1 1 0 FAM76 protein DnaJ PF00226.31 EGD85346.2 - 2.2e-10 40.5 0.3 3.9e-10 39.7 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 EGD85346.2 - 0.00051 20.3 1.5 0.0008 19.7 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) DUF2076 PF09849.9 EGD85346.2 - 0.0015 18.7 0.9 0.0026 17.9 0.9 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Bacteriocin_IIc PF10439.9 EGD85346.2 - 1 9.5 8.5 1.8 8.8 8.5 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide MFS_1 PF07690.16 EGD85348.1 - 4e-39 134.5 49.7 1.5e-38 132.7 49.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TadZ_N PF16968.5 EGD85348.1 - 0.13 12.0 1.4 0.34 10.6 1.4 1.6 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal PMM PF03332.13 EGD85349.1 - 9.2e-104 346.0 0.1 1.1e-103 345.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EGD85349.1 - 2.2e-05 24.3 0.0 0.00011 22.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.13 EGD85349.1 - 0.018 14.3 0.1 0.024 13.9 0.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1640 PF07798.11 EGD85350.2 - 1.2e-56 191.5 6.5 1.8e-56 190.9 6.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Trypsin_2 PF13365.6 EGD85351.1 - 2.7e-20 73.8 0.0 3.6e-19 70.1 0.0 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGD85351.1 - 0.0012 18.7 0.3 0.08 12.7 0.3 2.2 1 1 0 1 1 1 1 Trypsin Eisosome1 PF12757.7 EGD85352.2 - 1e-28 100.1 2.6 1e-28 100.1 2.6 2.6 3 0 0 3 3 3 1 Eisosome protein 1 MFS_1 PF07690.16 EGD85353.1 - 6e-16 58.3 42.9 1.6e-14 53.6 42.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily HlyIII PF03006.20 EGD85353.1 - 0.0005 19.9 9.2 0.0041 16.9 0.1 3.3 1 1 2 3 3 3 2 Haemolysin-III related LapA_dom PF06305.11 EGD85353.1 - 0.12 12.2 1.6 1.3 8.9 0.0 3.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Sugar_tr PF00083.24 EGD85353.1 - 1.3 7.8 28.8 8.8 5.1 25.2 2.8 1 1 1 2 2 2 0 Sugar (and other) transporter TRIQK PF15168.6 EGD85353.1 - 1.3 9.0 4.5 1.2 9.0 0.2 2.9 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family Pkinase PF00069.25 EGD85354.2 - 1.2e-43 149.3 0.0 2.1e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85354.2 - 8.5e-24 84.2 0.0 1.2e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD85354.2 - 2.8e-07 30.1 0.0 5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGD85354.2 - 1.3e-05 24.3 0.0 1.3e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain PRKG1_interact PF15898.5 EGD85354.2 - 0.032 15.1 2.6 0.09 13.7 2.6 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Kdo PF06293.14 EGD85354.2 - 0.088 12.2 0.0 0.088 12.2 0.0 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGD85354.2 - 0.61 10.0 3.3 0.86 9.5 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Prenyltrans PF00432.21 EGD85355.2 - 5.4e-27 93.2 10.5 2.4e-08 33.5 0.1 5.7 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EGD85355.2 - 0.0033 16.6 0.0 0.015 14.4 0.0 2.0 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain Ilm1 PF10311.9 EGD85356.1 - 9.6e-60 201.0 0.6 1.2e-59 200.7 0.6 1.1 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF4770 PF15994.5 EGD85356.1 - 0.069 13.4 0.1 0.094 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) LRRFIP PF09738.9 EGD85356.1 - 1.4 8.3 5.2 2.1 7.8 5.2 1.1 1 0 0 1 1 1 0 LRRFIP family DUF5357 PF17310.2 EGD85356.1 - 1.8 7.0 5.5 19 3.7 5.5 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5357) CFEM PF05730.11 EGD85358.1 - 7.2e-14 51.6 14.0 1.2e-13 51.0 14.0 1.3 1 0 0 1 1 1 1 CFEM domain SOG2 PF10428.9 EGD85358.1 - 5.7 6.0 7.8 6.5 5.8 7.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MFS_1 PF07690.16 EGD85359.2 - 2.1e-17 63.1 14.0 2.1e-17 63.1 14.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD85359.2 - 0.00096 18.1 2.1 0.00096 18.1 2.1 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 EGD85360.1 - 1.8e-10 40.3 41.9 1.8e-10 40.3 41.9 2.3 1 1 2 3 3 3 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGD85360.1 - 3.8e-09 36.5 6.9 3.8e-09 36.5 6.9 3.0 2 2 2 4 4 4 1 Ion channel regulatory protein UNC-93 BcrAD_BadFG PF01869.20 EGD85361.2 - 0.0002 20.9 0.0 0.00049 19.7 0.0 1.6 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ADP_ribosyl_GH PF03747.14 EGD85362.2 - 9.2e-29 101.1 0.0 1.2e-28 100.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase MerB PF03243.15 EGD85363.2 - 8.3e-13 48.6 0.1 9.4e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 Alkylmercury lyase DnaJ PF00226.31 EGD85365.1 - 2.2e-10 40.5 0.1 1.6e-09 37.7 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain SEEEED PF14797.6 EGD85365.1 - 1.7 8.8 10.3 0.029 14.5 2.9 1.7 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Rhomboid_SP PF12595.8 EGD85366.2 - 0.016 14.6 1.8 0.016 14.6 1.8 2.2 2 0 0 2 2 2 0 Rhomboid serine protease Frag1 PF10277.9 EGD85367.1 - 7.2e-38 130.3 11.6 8.4e-38 130.1 11.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4436 PF14494.6 EGD85367.1 - 0.049 12.9 1.8 0.083 12.2 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) DUF5134 PF17197.4 EGD85367.1 - 0.76 9.7 3.3 0.97 9.3 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) DUF2070 PF09843.9 EGD85367.1 - 8.1 4.6 16.9 0.19 10.0 10.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) XendoU PF09412.10 EGD85369.1 - 0.028 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Endoribonuclease XendoU SNF2_N PF00176.23 EGD85370.2 - 2.3e-56 191.0 0.0 5.3e-56 189.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.25 EGD85370.2 - 1.6e-09 37.5 8.5 4.7e-09 36.0 8.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGD85370.2 - 2.1e-09 37.1 8.9 5.5e-09 35.7 8.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGD85370.2 - 1.2e-07 31.4 7.8 1.2e-07 31.4 7.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGD85370.2 - 1.3e-07 31.8 11.3 3.7e-07 30.4 11.3 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EGD85370.2 - 5.1e-06 26.2 8.4 1.1e-05 25.1 8.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGD85370.2 - 9.9e-06 25.5 4.8 1.6e-05 24.8 3.6 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGD85370.2 - 1.2e-05 25.5 8.2 4.3e-05 23.7 8.2 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain Helicase_C PF00271.31 EGD85370.2 - 2.3e-05 24.7 0.0 5.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EGD85370.2 - 0.00033 20.6 7.4 0.00094 19.1 7.4 1.9 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 EGD85370.2 - 0.00067 19.7 0.0 0.006 16.6 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 EGD85370.2 - 0.0017 18.4 8.1 0.0043 17.2 8.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGD85370.2 - 0.11 12.5 3.7 0.28 11.3 3.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EGD85370.2 - 0.13 12.4 5.0 0.4 10.9 5.0 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EGD85370.2 - 0.17 11.7 7.0 0.49 10.2 7.0 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 EGD85370.2 - 0.24 11.3 5.1 0.81 9.6 5.1 2.0 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Zn_ribbon_17 PF17120.5 EGD85370.2 - 0.25 11.0 7.7 0.63 9.7 7.7 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1690 PF07956.11 EGD85370.2 - 0.49 10.8 0.0 0.49 10.8 0.0 4.0 4 1 0 4 4 3 0 Protein of Unknown function (DUF1690) zf-P11 PF03854.14 EGD85370.2 - 1.3 8.7 5.8 3.1 7.5 5.8 1.7 1 0 0 1 1 1 0 P-11 zinc finger Mito_carr PF00153.27 EGD85371.2 - 6.6e-45 151.0 0.7 1.9e-21 75.8 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial carrier protein Bacteriocin_IIc PF10439.9 EGD85371.2 - 0.048 13.8 1.5 3.1 8.0 0.2 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Ecm29 PF13001.7 EGD85372.2 - 2.7e-153 511.3 0.1 4.9e-150 500.5 0.0 4.2 3 1 0 4 4 4 2 Proteasome stabiliser HEAT PF02985.22 EGD85372.2 - 4.4e-05 23.4 4.5 0.63 10.5 0.1 8.2 9 0 0 9 9 9 1 HEAT repeat HEAT_EZ PF13513.6 EGD85372.2 - 0.002 18.6 4.8 0.58 10.7 0.0 5.7 5 0 0 5 5 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGD85372.2 - 0.023 15.3 1.9 0.31 11.6 0.1 3.9 4 2 0 4 4 4 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 EGD85372.2 - 0.33 10.0 11.3 3.5 6.6 0.6 4.8 4 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) WW PF00397.26 EGD85375.1 - 1.1e-11 44.6 0.6 2.5e-11 43.4 0.6 1.7 1 0 0 1 1 1 1 WW domain DUF4585 PF15232.6 EGD85375.1 - 0.036 14.1 0.0 0.036 14.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4585) PhoD PF09423.10 EGD85375.1 - 0.085 11.9 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 PhoD-like phosphatase Lipase_3 PF01764.25 EGD85376.1 - 8.9e-30 103.4 0.0 1.3e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 EGD85376.1 - 0.0032 17.1 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 EGD85376.1 - 0.0057 17.3 0.0 0.0084 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family GHMP_kinases_C PF08544.13 EGD85376.1 - 0.036 14.4 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 GHMP kinases C terminal Abhydrolase_5 PF12695.7 EGD85376.1 - 0.051 13.3 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Op_neuropeptide PF08035.11 EGD85376.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Opioids neuropeptide DUF2974 PF11187.8 EGD85376.1 - 0.16 11.5 0.0 1.7 8.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EGD85376.1 - 0.23 10.7 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 WD40 PF00400.32 EGD85377.1 - 2.4e-16 59.8 10.8 0.00059 20.6 0.2 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD85377.1 - 1.3e-06 28.6 0.0 0.0013 19.0 0.0 3.7 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGD85377.1 - 0.028 13.4 0.1 6.3 5.6 0.0 3.4 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Chi-conotoxin PF16981.5 EGD85377.1 - 0.18 12.0 0.1 0.74 10.1 0.1 2.0 1 1 0 1 1 1 0 chi-Conotoxin or t superfamily RRM_1 PF00076.22 EGD85378.1 - 1.6e-07 31.0 0.0 3.8e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGD85378.1 - 0.00019 21.0 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGD85378.1 - 0.0097 15.7 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EGD85378.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Autophagy_act_C PF03987.15 EGD85379.1 - 4.7e-15 55.9 0.1 1.7e-14 54.1 0.2 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain MFS_1 PF07690.16 EGD85382.1 - 5.1e-30 104.6 60.9 3e-28 98.8 41.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD85382.1 - 1.7e-08 33.8 37.6 0.00038 19.4 14.5 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter Tubulin_2 PF13809.6 EGD85382.1 - 0.13 11.5 0.6 0.19 10.9 0.6 1.1 1 0 0 1 1 1 0 Tubulin like Bac_rhodopsin PF01036.18 EGD85384.1 - 8.1e-35 120.4 20.1 9.2e-35 120.2 20.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein HSP20 PF00011.21 EGD85387.2 - 7.9e-19 67.7 0.3 8.7e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGD85387.2 - 9.5e-06 25.1 0.0 0.02 14.5 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Complex1_LYR PF05347.15 EGD85388.1 - 1.9e-17 63.0 2.4 2.3e-17 62.8 2.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGD85388.1 - 3e-07 31.1 0.7 3.7e-07 30.8 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EGD85388.1 - 0.032 14.8 0.1 0.04 14.5 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like FAA_hydrolase PF01557.18 EGD85389.1 - 4.5e-66 222.6 0.0 5.7e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 EGD85389.1 - 0.059 13.8 0.2 0.1 13.1 0.2 1.3 1 0 0 1 1 1 0 Type II transport protein GspH Proteasome PF00227.26 EGD85390.1 - 4e-30 104.7 0.0 4.8e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Gal4_dimer PF03902.13 EGD85390.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain HCNGP PF07818.13 EGD85391.1 - 2.1e-31 108.4 0.2 3.8e-31 107.6 0.2 1.4 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.26 EGD85392.1 - 5.6e-32 110.8 0.1 1.6e-31 109.3 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit DUF974 PF06159.13 EGD85392.1 - 0.07 12.9 0.0 0.096 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF974) KH_8 PF17903.1 EGD85393.1 - 1.4e-05 25.1 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EGD85393.1 - 0.044 13.6 0.6 0.098 12.5 0.6 1.6 1 0 0 1 1 1 0 KH domain MDM31_MDM32 PF08118.11 EGD85394.2 - 6.2e-246 817.1 0.1 4.2e-245 814.4 0.1 1.9 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins RhoGAP PF00620.27 EGD85395.1 - 5.7e-40 136.6 0.0 1.4e-39 135.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EGD85395.1 - 1.6e-14 54.3 0.0 5.6e-14 52.5 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGD85395.1 - 0.008 16.4 0.0 0.03 14.6 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4763 PF15960.5 EGD85395.1 - 0.014 14.7 0.5 0.014 14.7 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Erv26 PF04148.13 EGD85396.1 - 1e-92 309.6 0.1 1.2e-92 309.4 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Ferric_reduct PF01794.19 EGD85396.1 - 0.012 15.7 3.8 0.15 12.2 3.8 2.2 1 1 0 1 1 1 0 Ferric reductase like transmembrane component WBS_methylT PF12589.8 EGD85397.1 - 3.2e-15 56.6 3.9 5.6e-15 55.9 3.9 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EGD85397.1 - 2.2e-11 44.2 0.0 4.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD85397.1 - 2.3e-10 41.1 0.0 7.7e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD85397.1 - 3.7e-05 24.4 0.0 9.4e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD85397.1 - 0.00015 21.6 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGD85397.1 - 0.00048 19.9 0.0 0.0009 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EGD85397.1 - 0.0025 17.2 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGD85397.1 - 0.0046 16.8 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGD85397.1 - 0.036 13.4 0.0 0.43 9.8 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase ACT_7 PF13840.6 EGD85397.1 - 0.21 11.4 0.1 0.46 10.3 0.1 1.5 1 0 0 1 1 1 0 ACT domain Iso_dh PF00180.20 EGD85398.1 - 9.1e-84 281.6 0.0 1.1e-83 281.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Vps36-NZF-N PF16988.5 EGD85401.1 - 0.087 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-H2C2_5 PF13909.6 EGD85401.1 - 0.11 12.3 0.2 0.21 11.4 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Proteasome PF00227.26 EGD85402.1 - 2.2e-45 154.5 0.4 4e-32 111.2 0.0 2.7 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 EGD85402.1 - 5.3e-12 45.2 1.0 6.5e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RNA_pol_3_Rpc31 PF11705.8 EGD85402.1 - 0.11 12.8 10.5 0.15 12.3 10.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 EGD85402.1 - 1.7 7.9 10.8 2.3 7.4 10.8 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 EGD85402.1 - 3.2 8.2 12.0 5.8 7.4 12.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0560 PF10577.9 EGD85402.1 - 3.4 6.1 4.5 4 5.8 4.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FAM176 PF14851.6 EGD85402.1 - 5.3 6.7 7.6 8 6.1 7.6 1.3 1 0 0 1 1 1 0 FAM176 family DMRL_synthase PF00885.19 EGD85403.1 - 1e-56 190.7 0.2 1.2e-56 190.4 0.2 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase SIS PF01380.22 EGD85404.2 - 4.4e-57 191.6 0.0 2.5e-31 108.3 0.0 2.2 2 0 0 2 2 2 2 SIS domain SIS_2 PF13580.6 EGD85404.2 - 0.017 15.1 0.0 1.7 8.7 0.0 2.6 2 1 0 2 2 2 0 SIS domain N-SET PF11764.8 EGD85405.1 - 1.4e-58 197.8 0.4 6.3e-58 195.7 0.4 2.2 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 EGD85405.1 - 2.3e-27 94.4 0.3 5.9e-27 93.1 0.3 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 EGD85405.1 - 8.9e-20 71.7 0.2 8.9e-20 71.7 0.2 3.3 5 0 0 5 5 5 1 SET domain RRM_1 PF00076.22 EGD85405.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad60-SLD PF11976.8 EGD85407.1 - 1.2e-22 79.5 0.9 3.2e-18 65.3 0.5 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGD85407.1 - 0.00018 21.2 0.1 0.015 15.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family LSM PF01423.22 EGD85408.1 - 9.1e-20 70.1 0.0 1e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGD85408.1 - 0.0022 18.1 0.1 0.0026 17.9 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EGD85408.1 - 0.032 14.3 0.1 0.037 14.1 0.1 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain Hfq PF17209.3 EGD85408.1 - 0.09 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Hfq protein DUF1106 PF06523.11 EGD85408.1 - 0.13 12.3 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) IF-2B PF01008.17 EGD85409.1 - 5.3e-70 235.8 0.7 6.2e-70 235.6 0.7 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF4446 PF14584.6 EGD85410.2 - 0.067 13.2 0.5 0.099 12.6 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Pkinase PF00069.25 EGD85411.1 - 2.1e-15 56.8 0.0 3e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85411.1 - 3.1e-11 43.0 0.0 5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD85411.1 - 4.4e-05 22.9 0.0 5.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like GST_N PF02798.20 EGD85412.1 - 3e-14 53.1 0.0 5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGD85412.1 - 4.2e-14 52.5 0.0 1.1e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGD85412.1 - 4.2e-13 49.5 0.0 7e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGD85412.1 - 8.7e-09 35.5 0.0 1.6e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGD85412.1 - 1.1e-08 35.2 0.0 4.8e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGD85412.1 - 2.2e-08 34.0 0.1 4.4e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGD85412.1 - 0.067 13.9 0.0 0.22 12.3 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Adaptin_N PF01602.20 EGD85415.2 - 7.2e-18 64.4 0.2 1.7e-17 63.2 0.2 1.6 1 1 0 1 1 1 1 Adaptin N terminal region TPR_14 PF13428.6 EGD85416.1 - 3.1e-08 33.8 1.1 0.025 15.4 0.0 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGD85416.1 - 1.3e-06 28.8 0.2 0.075 13.5 0.0 3.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGD85416.1 - 1.2e-05 25.2 0.0 0.012 15.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGD85416.1 - 0.00011 22.3 0.0 0.14 12.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGD85416.1 - 0.00032 20.6 0.4 0.15 12.2 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EGD85416.1 - 0.0051 16.7 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal TPR_16 PF13432.6 EGD85416.1 - 0.036 14.7 0.9 2.3 9.0 0.0 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGD85416.1 - 0.099 12.8 0.7 0.24 11.6 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGD85416.1 - 0.1 12.5 0.0 1.1 9.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGD85416.1 - 0.17 12.2 0.7 24 5.3 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat BAF1_ABF1 PF04684.13 EGD85417.2 - 0.58 9.2 7.3 0.016 14.3 1.0 1.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Kinesin PF00225.23 EGD85420.2 - 7.8e-87 291.3 0.4 1.6e-86 290.3 0.4 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGD85420.2 - 2.2e-16 60.1 1.1 1.6e-14 54.1 0.0 2.8 3 0 0 3 3 3 1 Microtubule binding GNAT_acetyltr_2 PF13718.6 EGD85420.2 - 0.0074 15.7 0.8 0.65 9.4 0.4 2.5 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Cytochrom_B562 PF07361.11 EGD85420.2 - 0.018 15.7 0.2 0.018 15.7 0.2 3.0 3 0 0 3 3 2 0 Cytochrome b562 MPS2 PF17060.5 EGD85420.2 - 0.028 13.7 0.0 0.028 13.7 0.0 2.1 3 0 0 3 3 3 0 Monopolar spindle protein 2 MoCF_biosynth PF00994.24 EGD85420.2 - 0.028 14.1 0.2 0.17 11.6 0.0 2.4 3 0 0 3 3 3 0 Probable molybdopterin binding domain FlxA PF14282.6 EGD85420.2 - 0.033 14.2 7.1 0.086 12.8 1.8 3.8 3 0 0 3 3 3 0 FlxA-like protein Lebercilin PF15619.6 EGD85420.2 - 0.15 11.7 16.2 0.077 12.7 1.3 2.9 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Tho2 PF11262.8 EGD85420.2 - 0.62 9.2 4.3 1.3 8.2 4.3 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF641 PF04859.12 EGD85420.2 - 3.1 8.2 12.4 0.94 9.8 0.5 3.7 2 2 1 3 3 3 0 Plant protein of unknown function (DUF641) BBP1_C PF15272.6 EGD85420.2 - 6.2 6.6 14.0 2.4 8.0 0.8 3.6 3 1 0 3 3 3 0 Spindle pole body component BBP1, C-terminal Ank_2 PF12796.7 EGD85421.2 - 1.7e-28 99.0 0.1 6.3e-10 39.5 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD85421.2 - 2.1e-20 72.8 0.0 0.00021 21.8 0.0 6.0 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EGD85421.2 - 3.8e-15 55.5 0.0 0.29 11.7 0.0 6.5 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EGD85421.2 - 2.3e-13 50.1 0.1 0.0072 16.6 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD85421.2 - 1.3e-11 43.6 0.0 0.13 12.9 0.0 6.7 6 1 0 6 6 6 2 Ankyrin repeat PEGA PF08308.11 EGD85421.2 - 0.013 15.4 0.1 7.8 6.5 0.0 2.4 2 0 0 2 2 2 0 PEGA domain F-box-like PF12937.7 EGD85421.2 - 0.017 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 F-box-like NOGCT PF08155.11 EGD85423.1 - 0.13 12.3 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 NOGCT (NUC087) domain DAGAT PF03982.13 EGD85424.1 - 2.5e-91 305.7 0.0 3.1e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 EGD85424.1 - 0.054 13.2 3.2 0.12 12.1 3.2 1.5 1 0 0 1 1 1 0 Rer1 family G-patch PF01585.23 EGD85426.1 - 0.00045 20.1 0.0 0.0071 16.2 0.0 2.6 1 1 0 1 1 1 1 G-patch domain Asp-B-Hydro_N PF05279.11 EGD85426.1 - 0.053 13.6 24.4 0.068 13.2 24.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF966 PF06136.13 EGD85426.1 - 0.54 9.9 20.3 0.73 9.5 20.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CRT10 PF08728.10 EGD85426.1 - 0.92 7.6 8.6 1 7.5 8.6 1.1 1 0 0 1 1 1 0 CRT10 SLC12 PF03522.15 EGD85426.1 - 1.9 7.4 17.9 2.7 6.9 17.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 LAP1C PF05609.12 EGD85426.1 - 2.3 7.2 22.0 3 6.8 22.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 EGD85426.1 - 3.4 4.7 17.6 4.3 4.3 17.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Coilin_N PF15862.5 EGD85426.1 - 6.2 6.6 35.1 0.28 11.0 7.7 2.3 2 0 0 2 2 2 0 Coilin N-terminus DUF4551 PF15087.6 EGD85426.1 - 6.4 5.5 17.7 8.1 5.1 17.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FAM199X PF15814.5 EGD85427.1 - 0.098 11.7 7.9 0.1 11.6 7.9 1.0 1 0 0 1 1 1 0 Protein family FAM199X DUF2852 PF11014.8 EGD85427.1 - 0.43 10.7 3.5 0.24 11.6 1.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Fib_alpha PF08702.10 EGD85427.1 - 3.4 7.8 9.6 3 8.0 7.6 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Syja_N PF02383.18 EGD85428.1 - 2.3e-73 247.3 0.0 3.3e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EGD85428.1 - 1.2e-10 41.3 0.0 1.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DNA_pol_E_B PF04042.16 EGD85428.1 - 0.12 11.7 0.5 0.24 10.7 0.1 1.7 2 0 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.25 EGD85429.2 - 5e-62 209.7 0.0 5.9e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85429.2 - 2.2e-34 118.9 0.0 3e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD85429.2 - 0.071 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGD85429.2 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGD85429.2 - 0.15 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase IGR PF09597.10 EGD85430.1 - 2.9e-22 78.5 2.3 5.4e-22 77.6 2.3 1.5 1 0 0 1 1 1 1 IGR protein motif p450 PF00067.22 EGD85431.1 - 9.4e-70 235.6 0.0 1.2e-69 235.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 K-box PF01486.17 EGD85431.1 - 0.15 12.3 0.1 0.33 11.2 0.1 1.5 1 0 0 1 1 1 0 K-box region DUF3045 PF11243.8 EGD85431.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) Pkinase PF00069.25 EGD85432.1 - 2e-73 247.0 0.0 2.8e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85432.1 - 4e-35 121.3 0.0 5.3e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGD85432.1 - 8.8e-16 58.0 0.2 2.3e-15 56.7 0.2 1.8 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EGD85432.1 - 3e-08 33.3 0.0 4.1e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGD85432.1 - 2.4e-06 26.6 0.0 3.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 EGD85432.1 - 0.0014 18.9 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EGD85432.1 - 0.0065 15.8 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGD85432.1 - 0.033 13.1 0.2 0.049 12.6 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EGD85432.1 - 0.082 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PI3_PI4_kinase PF00454.27 EGD85433.1 - 2.7e-36 125.6 0.0 8.5e-34 117.5 0.0 2.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGD85433.1 - 1.4e-24 86.5 0.1 3.2e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 EGD85433.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Pkinase PF00069.25 EGD85434.1 - 1.9e-18 66.8 0.0 5.8e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85434.1 - 4.5e-05 22.9 0.0 6.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGD85434.1 - 0.0022 17.4 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EGD85434.1 - 0.063 12.2 0.1 0.089 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Chorion_2 PF03964.15 EGD85435.1 - 0.022 15.6 7.1 0.022 15.6 7.1 2.3 2 1 0 2 2 2 0 Chorion family 2 SR-25 PF10500.9 EGD85435.1 - 4.7 6.7 17.4 0.65 9.6 9.1 2.3 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein ArfGap PF01412.18 EGD85436.1 - 2e-32 111.7 2.3 2.2e-32 111.6 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EGD85436.1 - 1.7e-18 67.2 6.8 2.8e-18 66.5 6.8 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EGD85436.1 - 1.2e-11 45.0 0.4 4.1e-11 43.3 0.2 2.1 2 0 0 2 2 2 1 PH domain DUF3168 PF11367.8 EGD85437.1 - 0.0081 16.3 0.1 0.0093 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3168) LSM PF01423.22 EGD85438.1 - 1.6e-21 75.7 0.1 1.8e-21 75.6 0.1 1.0 1 0 0 1 1 1 1 LSM domain Ank_2 PF12796.7 EGD85439.1 - 1e-54 183.0 0.2 3.1e-12 46.9 0.0 5.9 3 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD85439.1 - 3.8e-46 154.9 6.2 4.7e-08 33.4 0.6 10.5 3 1 9 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 EGD85439.1 - 8.4e-37 124.0 11.7 8.1e-08 32.4 0.0 10.8 11 0 0 11 11 11 7 Ankyrin repeat Ank_3 PF13606.6 EGD85439.1 - 6.9e-36 118.2 2.6 0.00018 21.7 0.1 12.1 13 1 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 EGD85439.1 - 3.7e-28 97.2 9.1 5.8e-08 32.9 0.1 8.6 5 2 5 10 10 10 6 Ankyrin repeats (many copies) Asp_protease_2 PF13650.6 EGD85439.1 - 0.056 14.1 0.2 13 6.5 0.0 4.1 3 1 0 3 3 3 0 Aspartyl protease RVP PF00077.20 EGD85439.1 - 0.1 12.9 0.0 11 6.4 0.0 3.2 3 1 1 4 4 4 0 Retroviral aspartyl protease Fungal_trans_2 PF11951.8 EGD85441.1 - 5.5e-26 91.3 0.6 6.2e-20 71.4 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD85441.1 - 7.1e-09 35.6 9.0 1.4e-08 34.7 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.21 EGD85442.2 - 7.7e-55 186.4 5.7 9.1e-55 186.1 5.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD85442.2 - 1.4e-13 50.5 5.7 1.8e-13 50.2 5.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 EGD85442.2 - 0.26 10.1 0.8 0.34 9.7 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) APH PF01636.23 EGD85443.2 - 1.1e-07 32.1 0.1 6.3e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGD85443.2 - 0.019 14.3 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 EGD85443.2 - 0.024 13.5 0.1 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 EGD85443.2 - 0.067 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase RhoGAP PF00620.27 EGD85444.2 - 7.5e-14 51.8 0.1 2.8e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 EGD85444.2 - 2.4e-09 37.1 0.0 4.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) YojJ PF10372.9 EGD85444.2 - 0.033 14.3 1.3 0.22 11.6 0.5 2.7 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus UPF0054 PF02130.17 EGD85444.2 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 RTA1 PF04479.13 EGD85445.1 - 1.2e-34 119.7 2.4 1.7e-34 119.3 2.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Asp-Al_Ex PF06826.12 EGD85445.1 - 0.018 14.9 0.5 0.033 14.0 0.5 1.4 1 0 0 1 1 1 0 Predicted Permease Membrane Region AAA PF00004.29 EGD85446.1 - 3.7e-14 53.3 0.0 1.1e-13 51.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGD85446.1 - 8e-14 52.1 0.1 5.2e-13 49.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGD85446.1 - 4.2e-12 46.8 0.3 3.2e-11 43.9 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.11 EGD85446.1 - 1.3e-08 34.7 0.0 3.5e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain TniB PF05621.11 EGD85446.1 - 3.7e-07 29.7 0.0 6.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein TIP49 PF06068.13 EGD85446.1 - 0.00012 21.4 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 EGD85446.1 - 0.0002 20.9 0.0 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 EGD85446.1 - 0.0004 20.7 0.0 0.0011 19.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EGD85446.1 - 0.00047 19.5 0.0 0.00079 18.8 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain T2SSE PF00437.20 EGD85446.1 - 0.00083 18.5 0.1 0.0024 17.0 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_lid_10 PF17872.1 EGD85446.1 - 0.001 19.1 0.1 0.0033 17.5 0.0 1.8 2 0 0 2 2 1 1 AAA lid domain PIF1 PF05970.14 EGD85446.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase NTPase_1 PF03266.15 EGD85446.1 - 0.002 18.1 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_5 PF07728.14 EGD85446.1 - 0.0023 17.9 0.0 0.0053 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 EGD85446.1 - 0.0028 18.2 0.0 0.0086 16.6 0.0 1.9 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 EGD85446.1 - 0.0034 16.6 0.0 0.0064 15.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 EGD85446.1 - 0.0039 17.1 0.1 0.0068 16.3 0.1 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EGD85446.1 - 0.0046 16.7 0.0 0.0093 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGD85446.1 - 0.0046 17.3 0.0 0.017 15.5 0.0 2.0 2 0 0 2 2 1 1 RNA helicase RNA12 PF10443.9 EGD85446.1 - 0.0077 15.0 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 RNA12 protein AAA_18 PF13238.6 EGD85446.1 - 0.0085 16.6 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGD85446.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGD85446.1 - 0.034 13.9 0.0 0.095 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGD85446.1 - 0.042 13.6 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EGD85446.1 - 0.048 12.6 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 EGD85446.1 - 0.054 13.2 0.0 0.17 11.6 0.0 1.8 1 1 1 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 EGD85446.1 - 0.06 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 EGD85446.1 - 0.068 13.4 0.0 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGD85446.1 - 0.085 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 EGD85446.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DEAD PF00270.29 EGD85446.1 - 0.12 12.1 1.4 0.59 9.9 0.2 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase Sigma54_activat PF00158.26 EGD85446.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Stm1_N PF09598.10 EGD85446.1 - 6.2 7.7 9.4 1.9 9.4 2.6 2.9 2 0 0 2 2 2 0 Stm1 Thioredoxin_7 PF13899.6 EGD85447.1 - 4e-15 55.8 0.0 8.5e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 EGD85447.1 - 1.2e-13 50.6 0.1 2.2e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EGD85447.1 - 2.2e-07 31.0 0.0 1.3e-06 28.6 0.0 2.3 3 0 0 3 3 3 1 UBX domain Thioredoxin_2 PF13098.6 EGD85447.1 - 0.072 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Pkinase PF00069.25 EGD85449.2 - 3.3e-46 157.8 0.0 4.7e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85449.2 - 3.3e-32 111.8 0.0 4.8e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD85449.2 - 3.6e-06 26.0 0.5 3.9e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGD85449.2 - 0.2 11.0 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like COesterase PF00135.28 EGD85450.1 - 3.3e-64 217.6 0.0 5.9e-64 216.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGD85450.1 - 6.3e-08 32.7 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.18 EGD85451.2 - 4.1e-17 62.1 0.1 5.9e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MR_MLE_C PF13378.6 EGD85453.1 - 4.2e-37 127.8 0.0 6.2e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGD85453.1 - 5.3e-10 39.5 0.0 8.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Beta-lactamase PF00144.24 EGD85454.1 - 7.6e-27 94.4 0.0 1.4e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase adh_short_C2 PF13561.6 EGD85455.1 - 4.8e-48 163.7 0.0 7.8e-48 163.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD85455.1 - 1.4e-33 116.0 0.1 1.1e-31 109.9 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EGD85455.1 - 0.00092 19.2 0.4 0.0037 17.2 0.4 1.9 1 1 0 1 1 1 1 KR domain DUF3431 PF11913.8 EGD85456.1 - 1.5e-83 279.8 0.1 1.9e-83 279.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) FlxA PF14282.6 EGD85456.1 - 0.011 15.7 0.3 0.021 14.8 0.3 1.3 1 0 0 1 1 1 0 FlxA-like protein Amidohydro_2 PF04909.14 EGD85460.1 - 1.9e-15 57.5 0.0 1.4e-14 54.6 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase ADH_zinc_N PF00107.26 EGD85461.2 - 1.3e-25 89.8 0.3 2e-25 89.3 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGD85461.2 - 1.9e-05 25.7 0.1 3.4e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGD85461.2 - 0.0027 17.2 0.3 0.0081 15.7 0.3 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Methyltransf_32 PF13679.6 EGD85461.2 - 0.088 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SWIM PF04434.17 EGD85462.1 - 2.1e-05 24.1 0.4 4e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 SWIM zinc finger RecC_C PF17946.1 EGD85462.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 RecC C-terminal domain CobT PF06213.12 EGD85462.1 - 1.2 8.4 8.5 6.1 6.1 5.8 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SET PF00856.28 EGD85463.1 - 4.4e-10 40.2 1.4 1.9e-06 28.4 0.1 3.9 2 1 1 3 3 3 3 SET domain TPR_1 PF00515.28 EGD85463.1 - 0.026 14.3 1.2 0.14 12.0 0.3 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGD85463.1 - 0.027 14.6 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat SAP PF02037.27 EGD85463.1 - 0.036 13.8 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 SAP domain Allexi_40kDa PF05549.11 EGD85464.1 - 0.056 13.0 0.0 0.056 13.0 0.0 3.8 4 0 0 4 4 4 0 Allexivirus 40kDa protein zf-H2C2_2 PF13465.6 EGD85465.2 - 3.9e-10 39.7 16.2 9.4e-05 22.7 1.5 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGD85465.2 - 2.6e-07 30.7 23.9 0.024 15.1 7.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD85465.2 - 0.00022 21.8 20.9 0.15 12.9 5.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 EGD85465.2 - 0.014 15.7 6.3 0.025 14.9 6.3 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 EGD85465.2 - 0.019 15.0 19.2 0.14 12.2 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 EGD85465.2 - 0.073 12.9 0.4 0.18 11.7 0.4 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.8 EGD85465.2 - 0.14 12.5 7.4 1.7 9.0 2.4 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 EGD85465.2 - 0.19 11.5 6.9 3.8 7.4 1.6 3.0 1 1 1 2 2 2 0 GAGA factor DUF3268 PF11672.8 EGD85465.2 - 0.26 11.6 1.1 0.47 10.8 1.1 1.4 1 0 0 1 1 1 0 zinc-finger-containing domain zf-C2HE PF16278.5 EGD85465.2 - 0.33 11.4 15.1 0.43 11.1 1.1 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_9 PF16293.5 EGD85465.2 - 0.51 10.2 2.0 2.4 8.0 0.2 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) DZR PF12773.7 EGD85465.2 - 0.76 9.8 6.5 6.7 6.8 6.5 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-BED PF02892.15 EGD85465.2 - 2 8.5 9.9 6.5 6.9 5.5 2.8 1 1 1 2 2 2 0 BED zinc finger CCDC106 PF15794.5 EGD85465.2 - 2.1 8.0 0.0 2.1 8.0 0.0 2.9 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 106 zf_C2H2_ZHX PF18387.1 EGD85465.2 - 3.6 7.3 8.6 8.8 6.1 0.0 3.2 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 EGD85465.2 - 5.5 7.4 11.3 3.1 8.2 1.4 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF3074 PF11274.8 EGD85466.2 - 3.4e-14 53.2 0.1 2.4e-08 34.2 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) Stk19 PF10494.9 EGD85467.1 - 4.6e-84 281.9 0.0 5.7e-84 281.6 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Trehalose_PPase PF02358.16 EGD85468.2 - 3.1e-36 124.7 0.0 2.1e-35 122.0 0.0 2.1 1 1 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_20 PF00982.21 EGD85468.2 - 5.2e-30 104.5 0.1 1.2e-29 103.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 20 4HBT_3 PF13622.6 EGD85470.1 - 4e-49 168.1 0.0 4.6e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EGD85471.1 - 4e-06 27.1 0.0 6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily ADK PF00406.22 EGD85475.1 - 1.2e-40 139.1 0.1 2.7e-40 137.9 0.1 1.6 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGD85475.1 - 7.1e-35 120.4 0.1 1.1e-34 119.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGD85475.1 - 3.9e-08 33.9 0.0 6.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGD85475.1 - 7.5e-05 22.9 0.0 0.0014 18.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGD85475.1 - 0.0048 16.6 0.1 0.044 13.5 0.1 2.0 1 1 0 1 1 1 1 Thymidylate kinase Ploopntkinase3 PF18751.1 EGD85475.1 - 0.045 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MFS_1 PF07690.16 EGD85476.2 - 1.2e-24 86.9 15.8 1.5e-24 86.6 15.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 EGD85476.2 - 1.1 9.4 7.1 0.084 12.9 1.4 2.1 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Phage_holin_5_2 PF16079.5 EGD85476.2 - 6.9 7.1 10.1 1 9.7 0.8 2.7 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V Hum_adeno_E3A PF05393.11 EGD85478.1 - 0.0065 16.4 0.7 0.0065 16.4 0.7 2.3 1 1 1 2 2 2 1 Human adenovirus early E3A glycoprotein MARVEL PF01284.23 EGD85478.1 - 0.18 11.8 3.2 0.086 12.9 0.5 1.8 2 0 0 2 2 2 0 Membrane-associating domain DUF1218 PF06749.12 EGD85478.1 - 0.26 11.8 1.8 0.63 10.6 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) Cnd2 PF05786.14 EGD85479.1 - 0 1032.7 7.6 0 1032.5 7.6 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EGD85479.1 - 0.017 15.3 2.3 0.017 15.3 0.0 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Na_Ca_ex PF01699.24 EGD85480.1 - 3e-50 170.1 42.4 3.1e-27 95.4 16.7 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein EF-hand_4 PF12763.7 EGD85481.2 - 1.9e-24 85.6 0.0 1.6e-12 47.3 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 EGD85481.2 - 1.3e-10 40.8 0.2 3.8e-10 39.3 0.2 1.9 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.11 EGD85481.2 - 9.7e-06 25.9 60.5 3.3e-05 24.2 33.9 7.0 4 3 2 6 6 6 2 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 EGD85481.2 - 0.0002 20.7 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGD85481.2 - 0.00068 20.0 2.7 0.14 12.7 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 EGD85481.2 - 0.12 12.2 0.0 4.3 7.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair RNA_pol_L_2 PF13656.6 EGD85482.1 - 4.4e-26 90.5 0.0 6.6e-26 89.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGD85482.1 - 5.5e-10 38.5 0.0 8.9e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SIR2_2 PF13289.6 EGD85482.1 - 0.12 12.4 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 SIR2-like domain NMO PF03060.15 EGD85483.1 - 6.4e-33 114.5 3.5 3.7e-27 95.6 1.2 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EGD85483.1 - 1.7e-08 33.9 3.1 2.7e-08 33.2 3.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EGD85483.1 - 0.00019 20.7 2.1 0.00028 20.2 2.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EGD85483.1 - 0.0039 16.3 7.3 0.0064 15.5 4.5 2.3 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain HRCT1 PF15758.5 EGD85484.1 - 0.99 10.4 5.6 27 5.8 3.7 2.6 2 0 0 2 2 2 0 Histidine-rich carboxyl terminus protein 1 SNF2_N PF00176.23 EGD85486.1 - 1e-52 179.0 0.2 2.3e-51 174.6 0.2 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGD85486.1 - 4.5e-16 59.2 0.1 3e-15 56.5 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD85486.1 - 1.7e-05 24.9 0.0 8.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EGD85486.1 - 3e-05 23.8 11.9 3e-05 23.8 11.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 EGD85486.1 - 0.00053 19.0 0.0 0.0015 17.5 0.0 1.7 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.6 EGD85486.1 - 0.0086 16.4 11.9 0.0086 16.4 11.9 2.6 2 0 0 2 2 2 1 Ring finger domain Zn_Tnp_IS91 PF14319.6 EGD85486.1 - 9.3 6.4 14.1 0.27 11.3 2.7 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain C2 PF00168.30 EGD85487.1 - 7.6e-10 39.0 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pex2_Pex12 PF04757.14 EGD85488.2 - 9.1e-42 143.2 3.1 1.2e-41 142.8 3.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 EGD85488.2 - 2.7e-11 43.1 10.0 4.5e-11 42.4 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGD85488.2 - 6.7e-11 42.4 10.4 1.1e-10 41.7 10.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGD85488.2 - 1.4e-10 40.9 7.6 2.3e-10 40.2 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGD85488.2 - 2.7e-10 39.9 6.0 4.8e-10 39.1 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD85488.2 - 5e-08 32.8 9.3 1e-07 31.8 9.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGD85488.2 - 4.7e-07 29.6 7.2 8.2e-07 28.8 7.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGD85488.2 - 5.4e-07 29.5 6.6 9.5e-07 28.7 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGD85488.2 - 8.1e-07 29.2 7.6 1.7e-06 28.2 7.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGD85488.2 - 4.8e-06 26.6 9.4 8.5e-06 25.8 9.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EGD85488.2 - 0.0013 18.8 5.1 0.0027 17.8 5.1 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EGD85488.2 - 0.0085 16.1 3.2 0.016 15.2 3.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EGD85488.2 - 0.011 15.6 3.5 0.021 14.7 3.5 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 EGD85488.2 - 0.023 14.5 4.9 0.045 13.6 4.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EGD85488.2 - 0.23 11.3 8.2 0.51 10.2 8.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 EGD85488.2 - 0.28 10.5 0.9 0.51 9.7 0.9 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_11 PF17123.5 EGD85488.2 - 0.37 10.6 4.1 0.96 9.3 4.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGD85488.2 - 0.48 10.1 4.7 0.9 9.2 4.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type EXS PF03124.14 EGD85489.2 - 3.7e-57 194.1 7.5 1.5e-56 192.1 7.5 1.7 1 1 0 1 1 1 1 EXS family DUF3431 PF11913.8 EGD85490.1 - 4.8e-88 294.5 1.0 6e-88 294.2 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) NIR_SIR PF01077.22 EGD85491.2 - 1e-53 181.1 0.0 2e-46 157.4 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EGD85491.2 - 7.7e-29 99.4 0.0 8.9e-14 51.1 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EGD85491.2 - 3.4e-28 98.7 0.0 7.3e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Ras PF00071.22 EGD85493.1 - 8e-60 201.1 0.5 1e-59 200.8 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD85493.1 - 1.1e-36 125.7 0.2 1.7e-36 125.1 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD85493.1 - 4.9e-18 65.2 0.4 5.9e-18 64.9 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGD85493.1 - 4.7e-06 26.3 0.1 2.9e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGD85493.1 - 1.4e-05 25.1 0.1 2.8e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGD85493.1 - 1.5e-05 24.5 0.1 2.6e-05 23.7 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGD85493.1 - 2.3e-05 24.4 0.2 0.025 14.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGD85493.1 - 5.8e-05 22.6 0.3 7e-05 22.3 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 EGD85493.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EGD85493.1 - 0.081 13.0 0.4 9 6.3 0.0 2.7 2 1 1 3 3 3 0 Dynamin family TetR_C_16 PF17920.1 EGD85493.1 - 0.21 11.9 0.0 0.36 11.1 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ATP-synt_C PF00137.21 EGD85494.1 - 1.7e-25 89.2 28.7 1.8e-16 60.2 10.8 2.4 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 EGD85494.1 - 0.56 9.5 5.1 0.12 11.7 0.7 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 MoeA_N PF03453.17 EGD85495.2 - 1.4e-38 132.2 2.2 2.2e-38 131.5 2.2 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EGD85495.2 - 6.8e-29 100.4 0.0 4.3e-22 78.3 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_C PF03454.15 EGD85495.2 - 3.8e-18 65.4 0.1 1e-17 64.0 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DDHD PF02862.17 EGD85496.2 - 1.7e-26 93.8 0.0 1.7e-24 87.2 0.0 2.6 1 1 0 1 1 1 1 DDHD domain CENP-U PF13097.6 EGD85496.2 - 0.11 12.4 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Phe_hydrox_dim PF07976.12 EGD85499.2 - 3.1e-36 124.9 0.0 4.9e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_3 PF01494.19 EGD85499.2 - 5.1e-27 95.0 0.0 5.8e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DASH_Dad1 PF08649.10 EGD85504.1 - 1.7e-22 79.4 1.9 2.1e-22 79.0 1.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 EGD85504.1 - 0.035 14.1 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 Ras PF00071.22 EGD85505.1 - 2e-47 160.8 0.0 2.5e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD85505.1 - 5.6e-20 71.7 0.0 1e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD85505.1 - 0.00016 21.1 0.0 0.00026 20.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGD85505.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EGD85505.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PAP2 PF01569.21 EGD85506.1 - 4.6e-06 26.4 0.4 4.6e-06 26.4 0.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily Peptidase_C48 PF02902.19 EGD85507.2 - 8.6e-27 94.4 0.0 1.3e-26 93.8 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MSA_2 PF00985.17 EGD85508.1 - 9 6.6 8.9 18 5.6 8.9 1.4 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Fez1 PF06818.15 EGD85509.1 - 0.0017 18.8 1.1 0.0017 18.8 1.1 2.2 2 0 0 2 2 2 1 Fez1 FliJ PF02050.16 EGD85509.1 - 0.04 14.1 0.9 1.7 8.9 0.6 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein Spc7 PF08317.11 EGD85509.1 - 0.05 12.5 3.2 0.083 11.8 3.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 EGD85509.1 - 0.082 12.0 5.0 0.18 10.8 5.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4618 PF15397.6 EGD85509.1 - 0.22 10.9 6.8 1.7 8.0 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) APG6_N PF17675.1 EGD85509.1 - 0.24 11.9 3.6 0.68 10.5 3.6 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region COG5 PF10392.9 EGD85509.1 - 0.33 11.1 10.1 0.76 10.0 5.7 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 LPP PF04728.13 EGD85509.1 - 0.5 10.8 7.9 8.5 6.8 1.3 3.8 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.12 EGD85509.1 - 6.3 6.8 6.0 6.1 6.9 2.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 EGD85509.1 - 8.6 6.4 7.8 9e+02 -0.2 7.9 2.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EGD85509.1 - 8.9 6.4 6.6 24 5.0 3.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sulfotransfer_3 PF13469.6 EGD85510.1 - 0.0081 16.6 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_3 PF13469.6 EGD85511.1 - 0.17 12.3 0.1 2 8.7 0.1 2.3 1 1 0 1 1 1 0 Sulfotransferase family DUF664 PF04978.12 EGD85511.1 - 0.3 11.5 1.3 27 5.2 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF664) adh_short_C2 PF13561.6 EGD85512.1 - 1.4e-54 185.2 0.4 1.6e-54 184.9 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD85512.1 - 7.5e-47 159.3 0.3 9.4e-47 159.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD85512.1 - 2.9e-10 40.4 0.3 7.2e-10 39.1 0.3 1.6 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EGD85512.1 - 0.0019 18.4 0.0 0.0039 17.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DENN PF02141.21 EGD85514.2 - 1e-37 129.9 0.0 1.6e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EGD85514.2 - 0.00026 21.7 0.3 0.0012 19.6 0.1 2.2 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 EGD85514.2 - 0.087 13.4 8.5 0.034 14.7 5.0 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TMF_TATA_bd PF12325.8 EGD85514.2 - 1.4 9.2 17.3 0.47 10.7 3.9 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Cnn_1N PF07989.11 EGD85514.2 - 1.5 9.1 13.9 0.15 12.2 3.5 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Git3 PF11710.8 EGD85515.1 - 2e-22 80.0 20.5 4.8e-22 78.7 20.5 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EGD85515.1 - 1e-10 41.5 0.7 1e-10 41.5 0.7 2.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 EGD85515.1 - 2.3e-06 27.1 16.3 2.3e-06 27.1 16.3 2.0 1 1 2 3 3 3 1 7 transmembrane receptor (rhodopsin family) Baculo_11_kDa PF06143.11 EGD85515.1 - 9.9 5.8 11.3 0.63 9.7 0.9 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family MOR2-PAG1_N PF14222.6 EGD85516.2 - 3.2e-210 699.8 0.0 5.1e-210 699.1 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EGD85516.2 - 2.9e-87 292.7 1.0 6.6e-87 291.5 0.1 2.1 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EGD85516.2 - 2.6e-40 138.0 11.1 4.1e-18 64.5 0.1 4.1 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT_EZ PF13513.6 EGD85516.2 - 0.26 11.8 1.0 36 5.0 0.0 4.7 4 0 0 4 4 4 0 HEAT-like repeat FAD_binding_1 PF00667.20 EGD85517.1 - 2.2e-67 226.9 0.0 3.1e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGD85517.1 - 4.9e-35 120.8 0.8 9.5e-35 119.9 0.8 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGD85517.1 - 1.5e-21 77.1 0.0 1.4e-20 73.9 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EGD85517.1 - 0.095 12.9 0.1 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Flavodoxin domain RRM_1 PF00076.22 EGD85518.1 - 8e-22 76.9 0.2 1.6e-10 40.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAPS_reduct PF01507.19 EGD85519.1 - 5.3e-29 101.5 0.0 2.6e-27 96.0 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RPA_C PF08784.11 EGD85520.1 - 2.4e-14 53.8 0.2 9.5e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EGD85520.1 - 0.0007 19.5 0.0 0.0035 17.3 0.0 2.1 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DEAD PF00270.29 EGD85521.1 - 5.1e-47 159.9 0.0 1.1e-46 158.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD85521.1 - 4.6e-25 88.1 0.1 2e-24 86.1 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EGD85521.1 - 1e-19 70.5 1.6 4.4e-19 68.5 1.6 2.2 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Zn_clus PF00172.18 EGD85523.1 - 0.0003 20.8 10.5 0.00054 20.0 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.21 EGD85524.2 - 7.8e-41 140.2 14.9 9.6e-41 139.9 14.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD85524.2 - 1.8e-07 30.4 15.8 2.2e-07 30.1 15.8 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 EGD85524.2 - 0.0053 17.4 1.5 0.0053 17.4 1.5 2.0 1 1 1 2 2 2 1 PrgI family protein DEAD PF00270.29 EGD85525.1 - 1e-47 162.2 0.1 2e-47 161.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD85525.1 - 3.6e-24 85.3 0.0 2.6e-23 82.5 0.0 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGD85525.1 - 7.9e-20 70.8 0.0 2.6e-19 69.2 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGD85525.1 - 2.1e-08 34.4 0.0 7.7e-08 32.5 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EGD85525.1 - 0.016 15.4 0.1 0.082 13.1 0.0 2.2 2 0 0 2 2 2 0 Helicase C-terminal domain DnaJ PF00226.31 EGD85526.1 - 1.7e-14 53.7 1.3 5.8e-14 52.0 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain Afi1 PF07792.12 EGD85526.1 - 10 6.6 6.5 1.8 9.1 2.8 1.7 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking MatE PF01554.18 EGD85527.1 - 7.9e-57 191.4 32.1 5.3e-35 120.5 11.1 2.3 2 0 0 2 2 2 2 MatE DUF202 PF02656.15 EGD85528.2 - 4.6e-16 59.0 4.9 6.9e-16 58.4 1.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.12 EGD85528.2 - 0.32 11.1 1.7 3 8.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV NUDIX PF00293.28 EGD85529.2 - 7.1e-27 94.0 0.0 9.4e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain zf-C2H2 PF00096.26 EGD85531.1 - 1.1e-06 28.8 32.0 0.00077 19.8 3.4 4.6 5 0 0 5 5 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD85531.1 - 1.1e-05 25.9 28.0 0.0035 18.0 1.9 4.4 4 0 0 4 4 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGD85531.1 - 0.00014 22.2 14.4 0.2 12.1 0.3 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGD85531.1 - 0.0049 16.8 12.4 0.076 13.0 0.2 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGD85531.1 - 0.009 15.7 14.7 0.12 12.2 0.4 3.7 3 0 0 3 3 3 2 zinc-finger C2H2-type CpXC PF14353.6 EGD85531.1 - 0.1 12.6 7.7 1.6 8.8 0.4 2.3 1 1 1 2 2 2 0 CpXC protein Zn-ribbon_8 PF09723.10 EGD85531.1 - 0.13 12.4 9.4 1.3 9.2 2.1 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 EGD85531.1 - 0.26 11.6 11.5 0.16 12.3 4.9 3.2 1 1 2 3 3 3 0 C2H2-type zinc ribbon zinc-ribbons_6 PF07191.12 EGD85531.1 - 0.96 9.5 7.1 0.78 9.8 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbons Rubredoxin_2 PF18073.1 EGD85531.1 - 1.5 8.7 8.2 6 6.7 1.2 2.8 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-BED PF02892.15 EGD85531.1 - 4.1 7.5 11.1 8 6.6 2.1 3.0 1 1 2 3 3 3 0 BED zinc finger HEAT PF02985.22 EGD85532.2 - 2.8e-09 36.4 9.2 0.15 12.4 0.1 6.5 7 0 0 7 7 7 3 HEAT repeat WD40 PF00400.32 EGD85532.2 - 6.7e-08 33.1 10.0 0.00011 22.8 0.1 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.6 EGD85532.2 - 0.00025 21.4 1.3 7.6 7.0 0.0 4.4 3 1 1 4 4 4 2 HEAT repeats Pkinase PF00069.25 EGD85532.2 - 0.00031 20.2 0.0 0.00049 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.6 EGD85532.2 - 0.00081 19.8 0.1 0.03 14.8 0.1 3.3 3 1 0 3 3 3 1 HEAT-like repeat Tti2 PF10521.9 EGD85532.2 - 0.012 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Tti2 family RabGAP-TBC PF00566.18 EGD85533.1 - 5.3e-42 143.9 0.0 3.3e-40 138.0 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Peptidase_M6 PF05547.11 EGD85534.1 - 4.6e-06 25.3 1.2 0.00031 19.2 0.7 2.2 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 THF_DHG_CYH PF00763.23 EGD85536.2 - 0.0031 17.8 0.0 0.0045 17.3 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Abhydrolase_4 PF08386.10 EGD85536.2 - 0.011 15.8 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein DUF5642 PF18702.1 EGD85536.2 - 0.028 14.2 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5642) COesterase PF00135.28 EGD85540.1 - 1.6e-88 297.9 0.0 1.9e-88 297.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGD85540.1 - 7.5e-07 29.2 0.0 2e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD85540.1 - 6.2e-05 23.7 0.0 0.00011 22.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGD85540.1 - 9.1e-05 22.0 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EGD85540.1 - 0.0046 15.9 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme SmpA_OmlA PF04355.13 EGD85540.1 - 0.056 13.3 0.5 9.5 6.1 0.0 2.5 2 0 0 2 2 2 0 SmpA / OmlA family DUF1749 PF08538.10 EGD85540.1 - 0.059 12.4 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Nop14 PF04147.12 EGD85541.1 - 4.7e-290 964.8 26.7 6e-290 964.4 26.7 1.1 1 0 0 1 1 1 1 Nop14-like family FNIP_C PF14638.6 EGD85541.1 - 0.027 14.1 0.1 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 Folliculin-interacting protein C-terminus HEAT_2 PF13646.6 EGD85542.1 - 0.056 13.8 0.5 0.12 12.8 0.5 1.6 1 0 0 1 1 1 0 HEAT repeats PPR_2 PF13041.6 EGD85543.1 - 3.6e-08 33.5 0.1 0.38 11.0 0.0 5.6 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 EGD85543.1 - 0.005 16.9 0.1 1 9.5 0.0 3.2 3 0 0 3 3 3 1 Pentatricopeptide repeat domain ImcF-related_N PF14331.6 EGD85543.1 - 0.087 12.2 0.8 0.25 10.7 0.8 1.7 1 0 0 1 1 1 0 ImcF-related N-terminal domain PPR PF01535.20 EGD85543.1 - 0.15 12.4 1.7 7.9 7.0 0.1 4.4 6 0 0 6 6 6 0 PPR repeat ORC_WH_C PF18137.1 EGD85544.2 - 3.4e-24 85.5 0.1 4.7e-15 55.9 0.0 2.7 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal DUF3456 PF11938.8 EGD85544.2 - 0.044 14.3 0.3 0.1 13.1 0.2 1.5 1 1 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP FTCD_N PF07837.12 EGD85544.2 - 0.12 12.1 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain Sec66 PF09802.9 EGD85545.1 - 1.8e-78 262.3 1.0 2.1e-78 262.0 1.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 EGD85545.1 - 0.00018 21.5 0.1 0.00035 20.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3848) DUF2465 PF10239.9 EGD85545.1 - 0.01 15.1 0.1 0.015 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) DUF1539 PF07560.11 EGD85545.1 - 0.014 15.4 0.0 0.026 14.6 0.0 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) AAA PF00004.29 EGD85546.2 - 1.6e-12 48.0 0.0 4.6e-08 33.6 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD85546.2 - 4.5e-10 39.2 0.6 1.5e-09 37.5 0.0 2.1 3 0 0 3 3 3 1 AAA+ lid domain Bromodomain PF00439.25 EGD85546.2 - 9.8e-05 22.4 0.0 0.00025 21.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Malate_DH PF12434.8 EGD85546.2 - 0.16 12.0 1.9 0.73 9.9 1.9 2.1 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Tom5 PF10642.9 EGD85546.2 - 0.3 11.1 0.8 0.88 9.7 0.8 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase CPSF_A PF03178.15 EGD85548.2 - 1.5e-92 310.4 0.0 1.7e-92 310.2 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region MFS_1 PF07690.16 EGD85549.1 - 7.3e-46 156.7 41.8 1.3e-42 146.0 39.8 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGD85549.1 - 2.4e-15 56.0 26.1 2.4e-15 56.0 26.1 1.5 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PALP PF00291.25 EGD85550.2 - 4.1e-36 124.9 0.0 1.1e-33 117.0 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 EGD85550.2 - 1.4e-07 31.9 0.0 1.1e-06 29.1 0.0 2.3 1 1 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.25 EGD85551.1 - 4.8e-36 124.5 0.0 5.6e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85551.1 - 5.4e-28 98.0 0.0 2.1e-27 96.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGD85551.1 - 2.1e-05 23.7 0.0 2.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGD85551.1 - 2.6e-05 23.2 0.0 3.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGD85551.1 - 0.00049 20.1 0.0 0.003 17.5 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGD85551.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EGD85551.1 - 0.16 11.3 0.1 1.2 8.4 0.1 2.2 1 1 0 2 2 2 0 Kinase-like AAA_11 PF13086.6 EGD85553.1 - 1.8e-64 218.1 0.4 3.8e-64 217.0 0.4 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EGD85553.1 - 4e-57 193.1 0.0 1.2e-56 191.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGD85553.1 - 1.1e-13 51.4 0.0 2e-12 47.3 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.6 EGD85553.1 - 4.5e-11 43.3 0.0 3e-10 40.6 0.0 2.5 3 1 0 3 3 1 1 AAA domain Viral_helicase1 PF01443.18 EGD85553.1 - 1.3e-09 38.1 0.2 0.074 12.8 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EGD85553.1 - 9.6e-08 31.6 0.3 1.2e-06 28.0 0.3 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EGD85553.1 - 1.7e-07 31.4 0.0 5.3e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PIF1 PF05970.14 EGD85553.1 - 5.8e-06 25.7 0.0 0.085 12.0 0.0 2.4 2 0 0 2 2 2 2 PIF1-like helicase AAA_22 PF13401.6 EGD85553.1 - 8.3e-06 26.1 0.1 8.8e-05 22.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EGD85553.1 - 4.1e-05 23.3 0.2 0.00028 20.5 0.3 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EGD85553.1 - 4.1e-05 23.5 0.1 0.0057 16.5 0.0 3.2 2 1 0 2 2 2 1 Helicase AAA_16 PF13191.6 EGD85553.1 - 0.00018 22.0 0.1 0.00057 20.3 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EGD85553.1 - 0.00023 20.3 0.0 0.00044 19.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 EGD85553.1 - 0.00039 20.4 0.1 0.0011 18.9 0.1 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain PhoH PF02562.16 EGD85553.1 - 0.00053 19.5 0.0 0.017 14.6 0.0 2.7 1 1 0 1 1 1 1 PhoH-like protein TrwB_AAD_bind PF10412.9 EGD85553.1 - 0.0025 16.8 0.0 0.0049 15.8 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain UvrD_C PF13361.6 EGD85553.1 - 0.0038 16.6 0.5 1.4 8.2 0.0 3.1 2 2 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_24 PF13479.6 EGD85553.1 - 0.0086 15.8 0.0 0.025 14.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EGD85553.1 - 0.0092 16.4 0.1 0.051 14.0 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGD85553.1 - 0.011 15.8 0.0 0.062 13.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGD85553.1 - 0.013 15.2 0.0 0.038 13.7 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein UvrD_C_2 PF13538.6 EGD85553.1 - 0.017 14.9 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain 4HB_MCP_1 PF12729.7 EGD85553.1 - 0.028 14.0 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction CbiA PF01656.23 EGD85553.1 - 0.029 14.4 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TK PF00265.18 EGD85553.1 - 0.035 14.0 0.0 0.43 10.4 0.0 2.3 2 0 0 2 2 2 0 Thymidine kinase SRP54 PF00448.22 EGD85553.1 - 0.045 13.4 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain HEM4 PF02602.15 EGD85553.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Rad17 PF03215.15 EGD85553.1 - 0.07 13.0 0.1 0.81 9.6 0.0 2.2 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_33 PF13671.6 EGD85553.1 - 0.082 13.1 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain CmcI PF04989.12 EGD85553.1 - 0.093 12.4 0.0 0.22 11.2 0.0 1.5 1 1 0 1 1 1 0 Cephalosporin hydroxylase AAA_7 PF12775.7 EGD85553.1 - 0.11 12.0 0.0 0.47 9.9 0.0 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 EGD85553.1 - 0.11 12.9 0.0 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Herpes_ori_bp PF02399.15 EGD85553.1 - 0.12 10.4 0.0 0.18 9.8 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Mg_chelatase PF01078.21 EGD85553.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EGD85553.1 - 0.12 12.8 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 EGD85553.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EGD85553.1 - 0.18 12.2 0.0 0.49 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase HhH-GPD PF00730.25 EGD85554.2 - 9.4e-21 74.3 0.0 2e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGD85554.2 - 6.3e-07 28.9 0.0 1.9e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif UQ_con PF00179.26 EGD85555.1 - 2.1e-39 134.4 0.0 2.4e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGD85555.1 - 0.02 14.6 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 EGD85555.1 - 0.06 13.0 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Methyltransf_23 PF13489.6 EGD85556.2 - 3.4e-11 43.3 0.0 6.3e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD85556.2 - 0.00024 21.7 0.0 0.0004 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD85556.2 - 0.00026 21.7 0.0 0.00042 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD85556.2 - 0.0029 17.4 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD85556.2 - 0.0089 16.7 0.0 0.015 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF1802 PF08819.11 EGD85556.2 - 0.027 14.3 0.2 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1802) CheR PF01739.18 EGD85556.2 - 0.094 12.2 0.0 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain AMP-binding PF00501.28 EGD85560.1 - 1.6e-38 132.4 0.0 2.5e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD85560.1 - 7.2e-06 26.9 0.0 1.6e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cu_amine_oxid PF01179.20 EGD85561.1 - 9.9e-166 551.7 0.3 1.2e-165 551.4 0.3 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EGD85561.1 - 2.1e-05 24.8 0.0 5.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EGD85561.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Tim17 PF02466.19 EGD85562.1 - 5.2e-10 39.7 1.0 8.2e-10 39.0 1.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 EGD85562.1 - 0.47 10.6 3.6 3.5 7.8 0.0 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5518) zf-RING_2 PF13639.6 EGD85563.2 - 0.0039 17.5 15.8 0.049 14.0 15.4 2.3 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EGD85563.2 - 0.0046 17.0 4.8 0.011 15.8 4.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 EGD85563.2 - 0.045 13.1 1.7 0.054 12.9 0.3 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger zf-rbx1 PF12678.7 EGD85563.2 - 0.051 13.9 17.2 0.083 13.2 14.5 2.6 2 1 1 3 3 3 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGD85563.2 - 0.059 13.4 6.5 0.16 12.0 6.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EGD85563.2 - 0.21 11.5 7.7 0.46 10.4 7.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGD85563.2 - 0.29 11.0 8.4 0.74 9.7 3.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4551 PF15087.6 EGD85563.2 - 0.38 9.5 2.9 0.7 8.6 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-C3HC4_2 PF13923.6 EGD85563.2 - 1.8 8.4 10.3 12 5.8 6.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGD85563.2 - 3 8.1 10.3 10 6.4 10.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain COesterase PF00135.28 EGD85564.1 - 1.9e-81 274.5 0.0 1.2e-70 238.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGD85564.1 - 3e-10 40.3 0.0 5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold CitMHS PF03600.16 EGD85565.1 - 0.59 9.3 6.1 1.6 7.9 6.1 1.7 1 1 0 1 1 1 0 Citrate transporter Glyco_hydro_3 PF00933.21 EGD85566.1 - 3e-56 191.1 0.0 3.6e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain LIM PF00412.22 EGD85567.1 - 2.8e-16 59.5 20.0 2.9e-11 43.4 3.3 3.4 3 1 0 3 3 3 2 LIM domain His_Me_b4a2 PF18275.1 EGD85567.1 - 8.1 6.6 8.4 17 5.6 0.0 3.6 3 0 0 3 3 3 0 His-Me finger endonuclease beta4-alpha2 domain Peptidase_S10 PF00450.22 EGD85569.2 - 5.6e-74 250.0 0.1 7.1e-74 249.7 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DNA_pol_A_exo1 PF01612.20 EGD85570.1 - 0.024 14.4 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease Ribonucleas_3_3 PF14622.6 EGD85571.1 - 9.9e-07 29.0 0.0 1.4e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGD85571.1 - 0.0011 19.6 0.0 0.012 16.3 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease III domain NAD_binding_5 PF07994.12 EGD85572.1 - 5.1e-146 486.2 0.1 6e-146 485.9 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EGD85572.1 - 2.8e-45 153.0 0.6 6e-45 152.0 0.6 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF728 PF05304.12 EGD85573.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Amidase PF01425.21 EGD85574.2 - 9.6e-81 272.0 0.2 2.1e-79 267.6 0.2 2.1 1 1 0 1 1 1 1 Amidase RhoGAP PF00620.27 EGD85576.2 - 1.9e-38 131.7 0.0 3e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain SesA PF17107.5 EGD85579.1 - 1.2e-39 135.2 0.2 1.8e-39 134.7 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 EGD85579.1 - 7.6e-12 45.2 9.6 7.6e-12 45.2 9.6 1.6 2 0 0 2 2 2 1 Sigma domain on NACHT-NTPases Helo_like_N PF17111.5 EGD85579.1 - 0.037 13.4 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF2802 PF10975.8 EGD85579.1 - 0.055 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) SesA PF17107.5 EGD85580.1 - 7e-25 87.6 0.0 1.1e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 EGD85580.1 - 2e-12 47.0 9.1 3.3e-12 46.3 9.1 1.4 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases WD40 PF00400.32 EGD85581.1 - 1.1e-113 367.8 77.3 5.8e-10 39.6 0.1 14.4 15 0 0 15 15 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD85581.1 - 6.2e-34 116.2 22.9 0.0012 19.1 0.1 12.3 1 1 11 12 12 12 10 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD85581.1 - 2.9e-19 69.1 30.1 0.025 13.2 0.0 11.4 3 3 9 12 12 12 8 Nucleoporin Nup120/160 NACHT PF05729.12 EGD85581.1 - 5.1e-19 68.8 0.0 9.3e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 EGD85581.1 - 5.7e-14 52.5 0.4 1e-06 29.2 0.1 4.2 3 1 1 4 4 3 2 Ankyrin repeats (3 copies) eIF2A PF08662.11 EGD85581.1 - 1.6e-09 37.9 7.7 0.0012 18.7 0.2 4.9 4 2 0 5 5 5 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGD85581.1 - 2.7e-09 36.4 21.1 0.0095 14.9 2.3 8.3 1 1 6 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGD85581.1 - 3.5e-09 36.4 0.7 0.03 13.7 0.0 4.7 4 1 0 4 4 4 2 WD40-like domain Ank_4 PF13637.6 EGD85581.1 - 3.5e-09 37.0 0.0 0.0087 16.6 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGD85581.1 - 1.8e-07 31.3 0.1 0.0065 16.9 0.0 5.0 5 1 0 5 5 4 1 Ankyrin repeat Ank_3 PF13606.6 EGD85581.1 - 4.1e-07 29.8 0.0 0.0036 17.7 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EGD85581.1 - 3.2e-06 27.3 0.0 0.019 15.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Nucleoporin_N PF08801.11 EGD85581.1 - 8.4e-06 24.8 18.4 0.045 12.5 0.1 6.1 3 3 3 7 7 7 3 Nup133 N terminal like AAA_16 PF13191.6 EGD85581.1 - 5.6e-05 23.6 0.0 0.00016 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Cytochrom_D1 PF02239.16 EGD85581.1 - 0.00082 18.0 7.1 0.44 9.0 0.4 3.8 3 2 0 3 3 3 2 Cytochrome D1 heme domain NACHT_sigma PF17106.5 EGD85581.1 - 0.00088 19.4 3.8 0.0019 18.3 3.8 1.5 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases DUF5046 PF16465.5 EGD85581.1 - 0.013 15.0 0.1 0.25 10.7 0.1 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF5046) AAA_19 PF13245.6 EGD85581.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain Big_3_5 PF16640.5 EGD85581.1 - 8.2 6.7 5.7 29 5.0 0.1 3.4 4 0 0 4 4 3 0 Bacterial Ig-like domain (group 3) Methyltransf_PK PF05891.12 EGD85582.1 - 2.3e-65 220.2 0.0 2.6e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 EGD85582.1 - 9.2e-05 22.3 0.0 0.00046 20.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD85582.1 - 0.00076 20.1 0.1 0.002 18.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD85582.1 - 0.0013 19.4 0.1 0.003 18.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGD85582.1 - 0.009 15.3 0.1 0.018 14.3 0.1 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Pkinase PF00069.25 EGD85586.1 - 4.8e-14 52.4 0.0 2.5e-10 40.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain zf-Tim10_DDP PF02953.15 EGD85587.2 - 2e-15 56.2 6.2 2.9e-15 55.6 6.2 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Vicilin_N PF04702.12 EGD85587.2 - 0.06 13.2 1.9 0.078 12.8 1.9 1.2 1 0 0 1 1 1 0 Vicilin N terminal region YqzH PF14164.6 EGD85587.2 - 0.12 12.5 1.2 0.37 10.9 0.8 2.1 2 1 0 2 2 2 0 YqzH-like protein ADH_N PF08240.12 EGD85588.1 - 1.5e-26 92.4 0.7 3.5e-26 91.2 0.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGD85588.1 - 8.4e-19 67.8 0.1 1.6e-18 66.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGD85588.1 - 0.00062 19.1 0.6 0.001 18.4 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 EGD85588.1 - 0.007 16.6 0.2 0.033 14.5 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Amidase PF01425.21 EGD85589.2 - 2.5e-83 280.5 0.0 3.2e-82 276.9 0.0 2.0 1 1 0 1 1 1 1 Amidase PIG-F PF06699.11 EGD85590.1 - 1.4e-50 171.9 2.4 1.7e-50 171.7 2.4 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F FlxA PF14282.6 EGD85591.1 - 0.22 11.5 1.5 5.3 7.1 0.7 2.5 2 0 0 2 2 2 0 FlxA-like protein DUF4470 PF14737.6 EGD85592.1 - 5.8e-11 42.4 1.1 1.8e-10 40.9 1.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EGD85592.1 - 5.5e-10 39.2 10.8 1.2e-09 38.1 10.8 1.6 1 0 0 1 1 1 1 MYND finger PHINT_rpt PF14882.6 EGD85593.2 - 0.0041 17.4 0.1 0.01 16.1 0.1 1.6 1 0 0 1 1 1 1 Phage-integrase repeat unit NTP_transf_5 PF14907.6 EGD85593.2 - 0.098 12.3 0.5 0.7 9.5 0.5 2.0 1 1 0 1 1 1 0 Uncharacterised nucleotidyltransferase LMBR1 PF04791.16 EGD85594.1 - 4.7e-17 62.1 4.7 4.7e-17 62.1 4.7 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF5367 PF17329.2 EGD85594.1 - 0.029 14.5 2.0 0.029 14.5 2.0 4.4 7 1 0 7 7 7 0 Family of unknown function (DUF5367) SLATT_1 PF18181.1 EGD85595.1 - 0.081 12.8 1.4 0.13 12.2 0.7 1.6 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 MTHFR_C PF12225.8 EGD85595.1 - 0.19 11.4 0.1 0.37 10.5 0.1 1.5 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal CREPT PF16566.5 EGD85595.1 - 0.54 10.4 4.3 1.3 9.2 4.3 1.5 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour RXT2_N PF08595.11 EGD85595.1 - 3.3 7.7 6.1 0.28 11.2 0.8 1.9 2 1 0 2 2 2 0 RXT2-like, N-terminal Atg14 PF10186.9 EGD85596.1 - 6.5e-85 285.0 0.0 8.4e-85 284.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1192 PF06698.11 EGD85596.1 - 0.14 12.3 2.1 0.33 11.0 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) BBP1_C PF15272.6 EGD85596.1 - 0.17 11.7 2.2 0.29 11.0 2.2 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Prefoldin_2 PF01920.20 EGD85596.1 - 0.36 10.8 1.2 1.4 8.9 0.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit Filament PF00038.21 EGD85596.1 - 1.3 8.5 6.5 4 6.9 5.4 1.9 1 1 1 2 2 2 0 Intermediate filament protein Pkinase PF00069.25 EGD85598.1 - 4.5e-13 49.2 0.0 7.4e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85598.1 - 3.7e-08 33.0 0.0 4.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EGD85598.1 - 0.0018 17.9 0.1 0.0024 17.5 0.1 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF2401 PF10287.9 EGD85599.1 - 1.4e-77 260.4 0.0 2.6e-77 259.5 0.0 1.4 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EGD85599.1 - 7.3e-21 74.4 0.4 7.3e-21 74.4 0.4 1.8 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Zip PF02535.22 EGD85600.2 - 6.6e-47 160.3 7.8 3.5e-46 158.0 7.8 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter SelP_N PF04592.14 EGD85600.2 - 9.7 5.5 17.2 5.9 6.2 0.4 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Thiolase_N PF00108.23 EGD85601.1 - 6.5e-93 310.8 0.1 1e-92 310.2 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGD85601.1 - 2.6e-44 149.8 1.7 5.8e-44 148.7 1.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGD85601.1 - 0.0001 22.0 1.2 0.0004 20.0 1.2 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGD85601.1 - 0.036 13.9 1.6 1.1 9.1 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PS-DH PF14765.6 EGD85602.1 - 1e-64 218.7 0.0 1.6e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 EGD85602.1 - 1.7e-63 214.6 0.0 4.4e-63 213.2 0.0 1.8 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EGD85602.1 - 5.3e-62 208.9 0.0 1.2e-59 201.2 0.0 2.5 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 EGD85602.1 - 1.8e-57 194.5 0.0 3.2e-57 193.6 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EGD85602.1 - 4.6e-54 184.1 0.0 7e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGD85602.1 - 4.5e-31 107.3 0.2 1.4e-30 105.7 0.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGD85602.1 - 1.8e-23 83.2 0.0 3.4e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EGD85602.1 - 5e-18 65.7 0.0 1.8e-17 63.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EGD85602.1 - 2.2e-16 61.1 0.0 8.8e-16 59.2 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EGD85602.1 - 3e-12 46.5 0.0 2.9e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 EGD85602.1 - 9.5e-12 45.0 0.0 2.7e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EGD85602.1 - 3.1e-09 36.9 0.0 7.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD85602.1 - 4.6e-09 36.9 0.0 3.1e-08 34.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD85602.1 - 1.3e-08 35.3 0.0 7.7e-08 32.9 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD85602.1 - 1.8e-08 34.3 0.0 5e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GDP_Man_Dehyd PF16363.5 EGD85602.1 - 6.8e-08 32.3 0.0 1.2e-06 28.2 0.0 2.5 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGD85602.1 - 1.7e-07 30.5 0.0 0.0001 21.4 0.0 2.7 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EGD85602.1 - 2.6e-07 30.3 0.0 4.1e-06 26.4 0.0 2.6 3 0 0 3 3 3 1 short chain dehydrogenase ADH_N PF08240.12 EGD85602.1 - 4.4e-05 23.3 0.0 0.00013 21.8 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 EGD85602.1 - 0.0011 18.6 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TetR_C_16 PF17920.1 EGD85602.1 - 0.0029 17.8 0.0 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain PP-binding PF00550.25 EGD85602.1 - 0.0066 16.8 0.1 0.018 15.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site HipN PF18253.1 EGD85602.1 - 0.013 15.2 0.1 0.046 13.4 0.0 2.0 2 0 0 2 2 1 0 Hsp70-interacting protein N N-terminal domain CoA_trans PF01144.23 EGD85602.1 - 0.056 12.8 0.2 3.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Coenzyme A transferase Semialdhyde_dh PF01118.24 EGD85602.1 - 0.097 13.1 0.0 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain LysM PF01476.20 EGD85603.1 - 1.8e-16 59.9 0.0 0.00012 22.0 0.0 4.3 4 0 0 4 4 4 3 LysM domain Rab15_effector PF15208.6 EGD85603.1 - 0.0011 18.3 0.0 2.8 7.2 0.0 2.9 2 1 1 3 3 3 2 Rab15 effector CarbpepA_inh PF02977.15 EGD85603.1 - 0.091 12.6 5.6 16 5.4 0.1 4.6 4 0 0 4 4 4 0 Carboxypeptidase A inhibitor NLPC_P60 PF00877.19 EGD85603.1 - 0.1 12.6 0.2 36 4.4 0.0 3.3 4 0 0 4 4 4 0 NlpC/P60 family Phage_GPL PF05926.11 EGD85603.1 - 0.23 11.4 0.0 2 8.4 0.0 2.0 2 0 0 2 2 2 0 Phage head completion protein (GPL) UPF0203 PF05254.12 EGD85603.1 - 0.42 10.9 12.8 8.1 6.8 0.4 4.6 4 3 0 4 4 4 0 Uncharacterised protein family (UPF0203) DUF4653 PF15546.6 EGD85603.1 - 6.1 6.4 10.5 0.79 9.3 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) GTP_EFTU PF00009.27 EGD85604.2 - 5.8e-47 159.7 0.0 9e-47 159.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGD85604.2 - 2.7e-21 75.6 0.0 8.6e-21 74.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EGD85604.2 - 1.3e-19 70.0 0.0 4.3e-19 68.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGD85604.2 - 1.1e-10 41.7 0.0 2.8e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGD85604.2 - 3.4e-07 30.2 0.1 1.1e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EGD85604.2 - 1.1e-05 25.5 0.1 2.1e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGD85604.2 - 0.059 12.8 0.1 0.76 9.2 0.1 2.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF5505 PF17610.2 EGD85604.2 - 0.1 12.6 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5505) Chromate_transp PF02417.15 EGD85605.1 - 1.4e-59 200.8 35.6 1.5e-34 119.4 14.1 2.5 3 0 0 3 3 3 2 Chromate transporter SYS1 PF09801.9 EGD85605.1 - 0.37 11.0 2.5 18 5.5 0.0 2.9 3 0 0 3 3 3 0 Integral membrane protein S linking to the trans Golgi network adh_short_C2 PF13561.6 EGD85606.1 - 6.2e-49 166.7 1.9 1e-47 162.7 1.9 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD85606.1 - 2.5e-37 128.2 1.0 3.9e-36 124.4 1.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EGD85606.1 - 3.8e-07 29.8 0.3 1e-05 25.1 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGD85606.1 - 3e-05 24.3 0.0 6.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EGD85606.1 - 6.2e-05 22.6 0.0 0.0022 17.5 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 EGD85606.1 - 0.00051 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 EGD85606.1 - 0.00064 19.7 0.7 0.0022 17.9 0.7 2.0 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EGD85606.1 - 0.013 16.1 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 EGD85606.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGD85606.1 - 0.083 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 EGD85606.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FeS_assembly_P PF01883.19 EGD85607.1 - 1.7e-10 40.9 0.0 4.3e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Pheromone PF08015.11 EGD85607.1 - 0.38 11.8 2.5 2.2 9.4 0.0 2.9 2 1 0 2 2 2 0 Fungal mating-type pheromone CBFD_NFYB_HMF PF00808.23 EGD85610.1 - 0.034 14.4 0.8 0.18 12.1 0.1 2.3 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RRF PF01765.19 EGD85611.1 - 1.2e-45 155.3 2.1 1.7e-45 154.9 2.1 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Trimer_CC PF08954.11 EGD85611.1 - 0.036 13.6 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Trimerisation motif FliG_N PF14842.6 EGD85611.1 - 0.085 13.4 0.5 0.19 12.3 0.5 1.7 1 0 0 1 1 1 0 FliG N-terminal domain HSP70 PF00012.20 EGD85612.1 - 7.1e-227 754.4 8.1 7.9e-227 754.2 8.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGD85612.1 - 7.1e-16 57.9 0.7 4.7e-15 55.2 0.3 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGD85612.1 - 9.8e-05 22.2 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EGD85612.1 - 0.03 13.3 0.1 0.39 9.7 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DevR PF01905.16 EGD85612.1 - 0.085 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 Activator_LAG-3 PF11498.8 EGD85612.1 - 0.2 10.6 0.0 0.56 9.1 0.0 1.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 MscS_porin PF12795.7 EGD85612.1 - 0.29 10.7 2.6 0.18 11.3 0.4 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Bromodomain PF00439.25 EGD85613.1 - 5e-29 100.2 2.1 4e-16 58.9 0.1 3.2 3 0 0 3 3 3 2 Bromodomain QRPTase_C PF01729.19 EGD85613.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Trypan_PARP PF05887.11 EGD85613.1 - 1.5 8.8 31.3 0.95 9.4 17.1 2.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CKS PF01111.19 EGD85614.1 - 3e-34 117.1 1.4 3e-34 117.1 1.4 1.7 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Thioredoxin_4 PF13462.6 EGD85615.1 - 1.4e-10 41.6 0.0 7.7e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin UPF0020 PF01170.18 EGD85615.1 - 0.047 13.4 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DSBA PF01323.20 EGD85615.1 - 0.34 10.7 3.2 1.6 8.4 0.2 2.5 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF3844 PF12955.7 EGD85617.1 - 5.1e-36 123.0 4.1 1e-35 122.0 4.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) zf-RING_2 PF13639.6 EGD85618.1 - 2.5e-12 46.9 6.7 4e-12 46.3 6.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGD85618.1 - 1e-08 34.9 5.9 1.7e-08 34.2 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGD85618.1 - 1.6e-08 34.1 1.5 2.9e-08 33.3 1.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGD85618.1 - 3.8e-08 33.1 4.0 6.1e-08 32.4 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGD85618.1 - 2.8e-06 27.2 3.5 4.5e-06 26.5 3.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGD85618.1 - 6.3e-06 26.4 10.3 3e-05 24.2 10.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGD85618.1 - 0.00018 21.4 0.9 0.00018 21.4 0.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGD85618.1 - 0.0013 18.6 2.6 0.0021 17.9 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGD85618.1 - 0.003 17.6 3.2 0.008 16.2 3.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGD85618.1 - 0.016 14.9 4.1 0.03 14.0 4.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type OAD_gamma PF04277.13 EGD85618.1 - 0.058 14.0 0.0 0.49 11.0 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain zf-RING_4 PF14570.6 EGD85618.1 - 0.093 12.5 5.9 0.17 11.7 5.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 EGD85618.1 - 0.11 12.3 5.8 0.23 11.4 5.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 EGD85618.1 - 0.19 11.9 4.9 0.4 10.9 4.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGD85618.1 - 0.33 10.8 6.1 1.1 9.2 6.1 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EGD85618.1 - 0.5 10.6 3.5 1.6 9.0 3.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EGD85618.1 - 0.65 10.2 4.0 1.5 9.0 4.0 1.7 1 1 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 EGD85618.1 - 1 9.4 4.9 2.8 8.1 4.9 1.7 1 1 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 EGD85618.1 - 2.6 8.1 8.1 0.15 12.0 1.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Pro_isomerase PF00160.21 EGD85620.1 - 9.2e-51 172.2 0.5 1.1e-50 172.0 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2c PF01411.19 EGD85621.2 - 3.2e-188 626.7 0.1 3.2e-188 626.7 0.1 1.3 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EGD85621.2 - 4.3e-18 65.1 0.6 1.2e-17 63.7 0.6 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EGD85621.2 - 2.7e-14 53.7 1.4 2.7e-14 53.7 1.4 2.1 2 0 0 2 2 2 1 DHHA1 domain FIN1 PF17300.2 EGD85621.2 - 0.48 9.9 3.1 0.81 9.1 3.1 1.2 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 AAA_assoc_C PF09821.9 EGD85622.1 - 0.019 15.5 0.1 0.036 14.6 0.1 1.4 1 0 0 1 1 1 0 C-terminal AAA-associated domain DUF3752 PF12572.8 EGD85623.2 - 1.6e-46 158.6 13.9 1.6e-46 158.6 13.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) JHY PF15261.6 EGD85623.2 - 0.049 14.3 7.5 0.14 12.8 7.5 1.8 1 0 0 1 1 1 0 Jhy protein Peptidase_S10 PF00450.22 EGD85624.2 - 4.8e-25 88.8 0.0 6.3e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S8 PF00082.22 EGD85626.2 - 4.3e-18 65.6 2.9 5.7e-18 65.2 2.9 1.1 1 0 0 1 1 1 1 Subtilase family COP-gamma_platf PF08752.10 EGD85628.2 - 0.011 15.9 0.2 0.032 14.4 0.2 1.7 1 1 1 2 2 2 0 Coatomer gamma subunit appendage platform subdomain MIP PF00230.20 EGD85629.1 - 5.7e-60 202.8 3.8 7.7e-60 202.4 3.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2644 PF10841.8 EGD85629.1 - 0.39 11.0 6.7 0.86 9.9 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2644) FGGY_C PF02782.16 EGD85630.1 - 4.9e-70 235.3 1.7 5.5e-70 235.1 0.7 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGD85630.1 - 9.5e-69 231.7 0.0 1.3e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain APH PF01636.23 EGD85631.2 - 8.7e-09 35.6 0.9 1.7e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGD85631.2 - 0.02 14.2 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 EGD85631.2 - 0.036 12.9 0.6 0.05 12.4 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Mating_N PF12731.7 EGD85631.2 - 0.17 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Mating-type protein beta 1 A_deaminase PF00962.22 EGD85634.2 - 1.8e-95 320.0 0.0 2.5e-95 319.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Abhydrolase_6 PF12697.7 EGD85636.1 - 1.4e-20 74.9 0.0 1.7e-20 74.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGD85636.1 - 0.055 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Frigida PF07899.11 EGD85636.1 - 0.057 12.7 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Frigida-like protein Abhydrolase_1 PF00561.20 EGD85636.1 - 0.067 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD85636.1 - 0.068 12.4 0.0 0.13 11.5 0.0 1.6 2 1 0 2 2 2 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGD85636.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein VirB8 PF04335.13 EGD85636.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 VirB8 protein Abhydrolase_5 PF12695.7 EGD85636.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family F-box PF00646.33 EGD85637.1 - 0.00011 21.9 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGD85637.1 - 0.00025 20.9 0.1 0.0007 19.4 0.0 1.7 2 0 0 2 2 2 1 F-box-like RNase_P_p30 PF01876.16 EGD85638.1 - 7.4e-66 221.7 0.0 9.6e-66 221.3 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 p450 PF00067.22 EGD85639.1 - 2.1e-21 76.2 0.0 4.8e-21 75.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 EGD85640.1 - 1.5e-30 106.5 0.0 3.1e-30 105.4 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGD85640.1 - 1.4e-21 77.3 0.0 2.5e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGD85640.1 - 0.013 15.0 0.0 0.031 13.7 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 EGD85641.2 - 2.3e-15 56.4 54.8 3e-12 46.1 13.6 4.6 2 2 1 3 3 3 3 Major Facilitator Superfamily DUF3493 PF11998.8 EGD85641.2 - 2.8 8.2 5.5 3 8.1 0.7 3.3 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 p450 PF00067.22 EGD85643.2 - 2.1e-50 171.8 0.0 2.6e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 EGD85644.1 - 5.7e-21 74.8 0.0 7.9e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGD85644.1 - 0.0015 18.5 0.1 0.0039 17.1 0.0 1.7 2 0 0 2 2 2 1 Dimerisation domain Dimerisation PF08100.11 EGD85644.1 - 0.0051 16.8 0.0 0.017 15.2 0.0 2.0 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 EGD85644.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MarR_2 PF12802.7 EGD85644.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 MarR family AAA_19 PF13245.6 EGD85644.1 - 0.082 13.2 0.0 1.9 8.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain Rrf2 PF02082.20 EGD85644.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 EGD85644.1 - 0.18 11.7 0.0 0.46 10.4 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB AMP-binding PF00501.28 EGD85645.2 - 4.6e-48 163.9 0.0 6.4e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 EGD85645.2 - 5.4e-28 98.7 0.0 1.3e-27 97.4 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 EGD85645.2 - 4.7e-10 39.7 0.1 1.2e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_1 PF00561.20 EGD85645.2 - 5.8e-06 26.1 0.0 9.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD85645.2 - 0.00025 21.7 0.2 0.0005 20.7 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGD85645.2 - 0.00036 19.9 0.0 0.00066 19.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF4481 PF14800.6 EGD85645.2 - 0.17 11.3 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) Methyltransf_2 PF00891.18 EGD85646.2 - 4.1e-19 68.7 0.0 5e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 EGD85646.2 - 0.006 16.7 0.0 0.0074 16.4 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EGD85646.2 - 0.0084 16.8 0.0 0.012 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD85646.2 - 0.015 15.9 0.0 0.021 15.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGD85646.2 - 0.055 13.3 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGD85646.2 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 EGD85646.2 - 0.14 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Pkinase PF00069.25 EGD85647.1 - 7.5e-65 218.9 0.0 8.8e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85647.1 - 1.9e-19 70.0 0.0 2.6e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGD85647.1 - 6.8e-09 36.0 0.5 0.00014 21.9 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGD85647.1 - 0.0035 16.2 0.1 0.0089 14.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGD85647.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGD85647.1 - 0.029 13.9 0.8 0.06 12.9 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kinase-like PF14531.6 EGD85647.1 - 0.054 12.8 0.0 0.087 12.1 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Pkinase PF00069.25 EGD85648.2 - 2.1e-14 53.5 0.0 1.4e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85648.2 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Tugs PF17840.1 EGD85649.2 - 0.013 15.6 0.2 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain tRNA-synt_1 PF00133.22 EGD85650.2 - 1.9e-205 683.7 1.0 2.2e-204 680.1 1.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGD85650.2 - 4.2e-34 117.7 0.6 4.2e-34 117.7 0.6 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGD85650.2 - 6.6e-12 44.9 0.7 0.00034 19.5 0.0 4.6 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGD85650.2 - 8e-10 38.5 0.1 1.3e-05 24.8 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 PepSY PF03413.19 EGD85650.2 - 0.034 14.7 0.0 0.13 12.8 0.0 2.0 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Val_tRNA-synt_C PF10458.9 EGD85650.2 - 0.041 14.2 10.5 0.11 12.8 10.5 1.8 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 EGD85650.2 - 0.06 12.7 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DnaJ PF00226.31 EGD85652.1 - 4.4e-21 74.8 1.1 1.7e-20 72.9 1.1 2.1 1 0 0 1 1 1 1 DnaJ domain zf-B_box PF00643.24 EGD85652.1 - 0.031 14.4 2.0 0.06 13.5 2.0 1.5 1 0 0 1 1 1 0 B-box zinc finger Zn_ribbon_17 PF17120.5 EGD85652.1 - 0.041 13.5 2.2 0.072 12.7 2.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FYVE PF01363.21 EGD85652.1 - 0.76 10.0 6.2 0.39 10.9 3.2 2.0 2 0 0 2 2 2 0 FYVE zinc finger DUF116 PF01976.17 EGD85653.2 - 0.15 11.6 0.2 0.24 10.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF116 DUF3431 PF11913.8 EGD85654.1 - 4.4e-83 278.3 0.0 6.7e-83 277.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) MIP-T3_C PF17749.1 EGD85654.1 - 0.093 12.7 2.1 0.18 11.8 2.1 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region SurE PF01975.17 EGD85655.1 - 1.5e-35 122.8 0.2 2e-35 122.4 0.2 1.2 1 0 0 1 1 1 1 Survival protein SurE zf-rbx1 PF12678.7 EGD85656.2 - 1.9e-09 37.7 2.8 4.2e-09 36.6 2.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGD85656.2 - 1.4e-07 31.7 2.7 1.4e-07 31.7 2.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGD85656.2 - 2.3e-07 30.6 0.4 5.6e-07 29.3 0.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGD85656.2 - 7e-06 25.8 5.6 3.7e-05 23.5 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD85656.2 - 4.4e-05 23.4 1.0 0.00011 22.2 1.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGD85656.2 - 0.00012 21.8 3.1 0.00012 21.8 3.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGD85656.2 - 0.00022 21.2 1.1 0.01 15.8 0.3 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGD85656.2 - 0.00057 19.5 0.7 0.0012 18.5 0.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EGD85656.2 - 0.0016 18.3 4.3 0.021 14.8 5.0 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGD85656.2 - 0.0033 17.3 0.8 0.0033 17.3 0.8 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 YacG PF03884.14 EGD85656.2 - 0.018 14.8 0.4 0.052 13.3 0.4 1.8 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG zf-RING_11 PF17123.5 EGD85656.2 - 0.17 11.6 2.5 0.73 9.6 0.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger NOA36 PF06524.12 EGD85656.2 - 0.32 10.3 8.8 0.69 9.2 8.8 1.5 1 0 0 1 1 1 0 NOA36 protein zf-RING_4 PF14570.6 EGD85656.2 - 2.1 8.2 4.4 1 9.2 1.4 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain MFS_1 PF07690.16 EGD85657.2 - 1.6e-09 37.2 21.1 5.9e-08 32.0 10.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGD85657.2 - 7.3e-05 21.8 1.5 0.0042 16.0 0.1 2.3 2 0 0 2 2 2 2 MFS_1 like family ATG22 PF11700.8 EGD85657.2 - 0.00013 20.8 0.3 0.014 14.1 0.0 2.5 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like Nucleoside_tran PF01733.18 EGD85657.2 - 0.088 12.2 0.7 0.52 9.7 0.0 2.1 2 0 0 2 2 2 0 Nucleoside transporter DUF2627 PF11118.8 EGD85657.2 - 4.8 7.8 6.9 20 5.8 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2627) BT1 PF03092.16 EGD85657.2 - 9.2 4.4 9.8 4.4 5.4 0.3 2.9 3 0 0 3 3 3 0 BT1 family ATP_transf PF09830.9 EGD85660.1 - 7.5e-24 83.7 0.2 1.4e-23 82.8 0.2 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 EGD85660.1 - 0.0025 17.6 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) DUF4931 PF16285.5 EGD85660.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4931) HIT PF01230.23 EGD85660.1 - 0.058 14.1 0.1 0.13 13.0 0.1 1.6 1 0 0 1 1 1 0 HIT domain GalP_UDP_transf PF01087.22 EGD85660.1 - 0.096 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain zf-C2H2 PF00096.26 EGD85664.1 - 0.00039 20.7 21.4 0.59 10.7 1.0 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD85664.1 - 0.082 13.8 19.6 1.1 10.3 0.6 5.1 4 1 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 EGD85664.1 - 2.7 8.7 5.6 30 5.3 0.5 3.4 3 0 0 3 3 3 0 FOXP coiled-coil domain RPN7 PF10602.9 EGD85665.1 - 3.5e-51 173.3 0.1 5.7e-51 172.7 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGD85665.1 - 1.7e-09 38.1 0.0 5.4e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 PCI domain DSBA PF01323.20 EGD85666.2 - 1e-07 32.0 0.0 1.1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain adh_short PF00106.25 EGD85667.1 - 5.1e-27 94.6 0.6 2.4e-17 63.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGD85667.1 - 1.2e-20 74.1 0.0 2.4e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD85667.1 - 0.0027 17.6 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EGD85667.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 EGD85667.1 - 0.13 12.1 0.2 4.8 7.0 0.2 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LtrA PF06772.11 EGD85668.2 - 1.6e-22 80.2 19.6 1.6e-22 80.2 19.6 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) LSM PF01423.22 EGD85670.1 - 5.3e-23 80.5 0.5 5.9e-23 80.4 0.5 1.0 1 0 0 1 1 1 1 LSM domain Peptidase_M1_N PF17900.1 EGD85671.2 - 0.00056 20.1 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 EGD85671.2 - 0.0018 17.9 0.0 0.0041 16.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain CDP-OH_P_transf PF01066.21 EGD85672.1 - 1.1e-15 58.1 0.0 1.1e-15 58.1 0.0 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PALP PF00291.25 EGD85673.1 - 8.7e-38 130.4 0.1 9.9e-38 130.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CPSase_L_D2 PF02786.17 EGD85678.1 - 7.2e-107 355.7 0.0 5.1e-83 277.7 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EGD85678.1 - 1.3e-41 141.8 0.1 3.3e-41 140.5 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EGD85678.1 - 5e-17 62.0 0.0 2.1e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGD85678.1 - 1.2e-15 57.6 0.1 3.4e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EGD85678.1 - 2.7e-10 40.1 0.0 0.0012 18.6 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 EGD85678.1 - 3.2e-05 23.6 0.0 0.041 13.5 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 EGD85678.1 - 0.00014 21.4 0.0 0.024 14.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 EGD85678.1 - 0.00052 19.8 0.0 0.061 13.1 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pkinase PF00069.25 EGD85680.1 - 1.7e-10 40.7 0.0 2.6e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85680.1 - 1.3e-06 27.9 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGD85680.1 - 9.7e-06 25.7 0.1 1.5e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGD85680.1 - 0.00013 21.4 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGD85680.1 - 0.0016 18.0 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EGD85680.1 - 0.0059 16.2 0.0 0.008 15.8 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EGD85680.1 - 0.024 13.4 0.0 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EGD85680.1 - 0.087 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SET PF00856.28 EGD85681.2 - 1.8e-15 57.7 0.1 3.8e-14 53.4 0.0 2.3 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.18 EGD85681.2 - 7.3e-10 38.8 5.9 7.3e-10 38.8 5.9 2.1 2 0 0 2 2 2 1 MYND finger Rtf2 PF04641.12 EGD85681.2 - 0.00019 20.9 0.2 0.00036 20.0 0.2 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger Ribosomal_S19 PF00203.21 EGD85682.1 - 5.4e-33 112.7 0.3 7.4e-33 112.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 EGD85683.1 - 1e-26 93.3 8.9 1.3e-26 93.0 8.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein SPT2 PF08243.11 EGD85684.1 - 9.4e-12 45.4 13.4 9.4e-12 45.4 13.4 2.2 2 0 0 2 2 2 1 SPT2 chromatin protein Carb_kinase PF01256.17 EGD85685.2 - 1.3e-36 126.4 0.1 4.8e-35 121.2 0.0 2.0 2 0 0 2 2 2 2 Carbohydrate kinase zf-C2H2 PF00096.26 EGD85686.1 - 0.0051 17.2 0.2 0.0051 17.2 0.2 7.1 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EGD85686.1 - 1.3 9.4 14.0 0.32 11.3 0.7 3.3 3 1 1 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 EGD85686.1 - 3 8.0 9.3 0.28 11.3 1.1 3.0 2 1 1 3 3 3 0 Aberrant zinc-finger Inhibitor_I9 PF05922.16 EGD85687.2 - 9.8e-15 55.0 0.0 1.9e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 EGD85687.2 - 1.9e-12 47.1 5.0 8.3e-12 45.0 5.0 1.8 1 1 0 1 1 1 1 Subtilase family CLN3 PF02487.17 EGD85687.2 - 0.2 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 CLN3 protein zf-C2H2 PF00096.26 EGD85688.1 - 0.0037 17.7 26.0 0.098 13.2 0.5 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 EGD85688.1 - 0.017 15.7 1.6 0.017 15.7 1.6 3.4 2 1 1 3 3 3 0 FOXP coiled-coil domain Methyltransf_16 PF10294.9 EGD85691.2 - 0.055 13.2 0.0 4.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Lysine methyltransferase Cys_Met_Meta_PP PF01053.20 EGD85693.1 - 5.6e-136 453.0 0.0 6.4e-136 452.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGD85693.1 - 8.7e-06 25.1 0.1 1.3e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGD85693.1 - 0.0037 16.6 0.5 0.009 15.4 0.5 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EGD85693.1 - 0.0094 15.3 0.1 0.016 14.5 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGD85693.1 - 0.011 14.8 0.9 0.013 14.5 0.1 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Crinivirus_P26 PF07416.11 EGD85693.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Crinivirus P26 protein RNA_pol_Rbc25 PF08292.12 EGD85694.2 - 7.4e-35 120.0 0.9 2.9e-34 118.1 0.9 1.8 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EGD85694.2 - 1.1e-15 57.7 0.0 1.9e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.9 EGD85695.1 - 7.1e-11 41.8 5.9 7.1e-11 41.8 5.9 4.3 2 1 2 4 4 4 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 EGD85695.1 - 5.2e-07 29.4 5.8 8.4e-07 28.8 5.8 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGD85695.1 - 0.0001 22.3 5.0 0.00018 21.5 5.0 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGD85695.1 - 0.0081 15.9 4.1 0.012 15.4 4.1 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger GPI-anchored PF10342.9 EGD85696.1 - 5.4e-14 52.7 0.0 5.4e-14 52.7 0.0 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 EGD85696.1 - 0.058 12.6 15.0 0.061 12.5 15.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RRM_1 PF00076.22 EGD85697.1 - 3.2e-11 42.9 0.4 2.9e-07 30.2 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hid1 PF12722.7 EGD85697.1 - 5.4 5.0 14.8 7.2 4.6 14.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein APH PF01636.23 EGD85698.2 - 1.9e-15 57.5 0.0 2.4e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGD85698.2 - 0.00016 21.4 0.0 0.0091 15.6 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EGD85698.2 - 0.0039 16.8 0.0 0.0097 15.5 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EGD85698.2 - 0.017 14.3 0.6 0.19 10.9 0.0 2.5 3 0 0 3 3 3 0 Fructosamine kinase Pkinase_Tyr PF07714.17 EGD85698.2 - 0.022 14.1 0.0 2.1 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase EcKinase PF02958.20 EGD85698.2 - 0.042 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 EGD85698.2 - 0.16 10.8 0.2 0.3 9.9 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF553 PF04473.12 EGD85699.1 - 0.13 11.8 0.4 0.59 9.6 0.4 1.9 1 1 0 1 1 1 0 Transglutaminase-like domain Sds3 PF08598.11 EGD85700.2 - 4.7e-12 46.4 0.8 4.7e-12 46.4 0.8 2.3 2 0 0 2 2 2 1 Sds3-like DUF4940 PF16298.5 EGD85700.2 - 0.045 13.4 0.1 0.62 9.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4940) SMN PF06003.12 EGD85702.2 - 0.12 11.6 2.7 0.23 10.7 2.7 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) CSN8_PSD8_EIF3K PF10075.9 EGD85703.1 - 1.5e-14 54.2 0.0 2.1e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family ATP-synt_E PF05680.12 EGD85704.1 - 1.3e-21 76.7 0.2 1.4e-21 76.7 0.2 1.0 1 0 0 1 1 1 1 ATP synthase E chain Drf_GBD PF06371.13 EGD85704.1 - 0.047 13.3 0.0 0.054 13.1 0.0 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain WD40 PF00400.32 EGD85705.2 - 0.00014 22.5 11.9 1.8 9.6 0.1 6.1 6 1 0 6 6 6 3 WD domain, G-beta repeat NUDE_C PF04880.13 EGD85705.2 - 0.2 12.2 2.5 0.55 10.7 2.5 1.9 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PMT PF02366.18 EGD85707.2 - 2.5e-71 240.1 13.8 4.2e-71 239.4 13.8 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGD85707.2 - 6e-69 231.6 2.2 6e-69 231.6 2.2 3.0 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGD85707.2 - 1.4e-20 73.9 0.5 2.9e-20 72.9 0.5 1.5 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 EGD85707.2 - 0.0034 17.6 3.6 0.0034 17.6 3.6 3.1 3 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Pirin PF02678.16 EGD85708.1 - 3.3e-30 104.3 0.1 6.2e-30 103.4 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGD85708.1 - 6e-25 87.6 0.0 1.7e-24 86.1 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EGD85708.1 - 0.00013 21.6 1.6 0.0023 17.6 1.1 2.5 2 1 0 2 2 2 1 Cupin domain APH PF01636.23 EGD85709.1 - 7.8e-18 65.3 0.1 1.9e-17 64.0 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGD85709.1 - 1.7e-05 24.3 0.0 0.028 13.8 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGD85709.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EGD85709.1 - 0.021 14.4 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 EGD85709.1 - 0.096 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 EGD85709.1 - 0.18 11.1 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain PRKCSH PF07915.13 EGD85712.1 - 6.2e-19 68.8 0.1 6.2e-19 68.8 0.1 2.9 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein SHD1 PF03983.12 EGD85713.1 - 2e-33 114.0 0.0 3.4e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 EGD85713.1 - 1.3e-32 111.2 4.7 1.8e-11 43.5 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 EGD85713.1 - 3.8e-30 103.5 5.4 2.9e-11 43.1 0.1 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 EGD85713.1 - 2.4e-20 71.9 0.3 6.6e-08 32.1 0.0 4.6 4 0 0 4 4 4 4 Variant SH3 domain SAM_4 PF18017.1 EGD85713.1 - 4.4e-05 23.4 0.0 0.00014 21.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 EGD85713.1 - 0.021 14.9 0.7 1.7 8.7 0.0 3.4 4 0 0 4 4 4 0 SH3 domain SH3_3 PF08239.11 EGD85713.1 - 0.19 12.0 1.3 2.1 8.7 0.1 2.8 3 0 0 3 3 3 0 Bacterial SH3 domain DUF3669 PF12417.8 EGD85714.1 - 0.11 12.7 6.3 3.3 8.0 0.7 3.4 3 0 0 3 3 3 0 Zinc finger protein SoxY PF13501.6 EGD85714.1 - 0.13 12.4 1.1 0.38 11.0 0.3 2.2 4 0 0 4 4 4 0 Sulfur oxidation protein SoxY CDC45 PF02724.14 EGD85714.1 - 3.2 5.9 5.6 2.6 6.2 4.5 1.4 2 0 0 2 2 2 0 CDC45-like protein Mitofilin PF09731.9 EGD85714.1 - 3.7 6.3 13.1 5.1 5.8 13.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HSCB_C PF07743.13 EGD85715.1 - 7.7e-19 68.0 1.5 1.3e-18 67.2 0.4 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EGD85715.1 - 4.1e-05 23.6 0.1 0.00022 21.3 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain DUF4352 PF11611.8 EGD85715.1 - 0.062 13.6 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) 3Beta_HSD PF01073.19 EGD85716.2 - 5.6e-09 35.4 0.2 1e-08 34.5 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGD85716.2 - 6e-05 22.6 0.1 0.00017 21.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGD85716.2 - 0.00041 20.3 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGD85716.2 - 0.028 13.6 0.0 0.14 11.3 0.0 1.9 1 1 0 1 1 1 0 Male sterility protein NmrA PF05368.13 EGD85716.2 - 0.17 11.4 0.1 0.51 9.9 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family F-box-like PF12937.7 EGD85717.1 - 0.00027 20.8 0.5 0.00027 20.8 0.5 2.3 2 0 0 2 2 2 1 F-box-like ATP-synt_D PF01813.17 EGD85717.1 - 0.0016 18.3 0.1 0.0031 17.4 0.1 1.4 1 0 0 1 1 1 1 ATP synthase subunit D F-box PF00646.33 EGD85717.1 - 0.023 14.6 2.7 0.023 14.6 1.0 1.9 2 0 0 2 2 2 0 F-box domain WD40 PF00400.32 EGD85718.1 - 1.3e-32 111.3 22.0 2.7e-07 31.2 0.4 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat PRP4 PF08799.11 EGD85718.1 - 4.8e-14 51.6 0.8 4.8e-14 51.6 0.8 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EGD85718.1 - 4.5e-11 42.9 0.1 0.061 13.6 0.0 5.7 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGD85718.1 - 0.011 15.1 0.0 0.17 11.2 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain Nbas_N PF15492.6 EGD85718.1 - 0.059 12.7 0.0 4.1 6.6 0.0 2.5 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal SpoIIE PF07228.12 EGD85719.1 - 3.4e-11 43.4 0.1 1.1e-09 38.4 0.1 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EGD85719.1 - 3.4e-07 30.1 0.2 7e-07 29.1 0.2 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EGD85719.1 - 5.1e-06 26.3 0.1 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C ComA PF02679.15 EGD85720.1 - 4.9e-88 294.7 0.0 5.8e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) PWWP PF00855.17 EGD85722.1 - 4.8e-17 62.2 0.1 4.8e-17 62.2 0.1 3.6 2 1 1 3 3 3 1 PWWP domain OPT PF03169.15 EGD85723.2 - 2.9e-85 287.2 48.5 3.3e-85 287.0 48.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RBP_receptor PF14752.6 EGD85723.2 - 2.4 6.6 6.6 0.24 9.9 2.0 1.5 2 0 0 2 2 2 0 Retinol binding protein receptor DUF3632 PF12311.8 EGD85724.2 - 0.00032 21.2 0.0 0.00035 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Pkinase PF00069.25 EGD85725.2 - 1.6e-20 73.6 0.0 4.4e-20 72.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85725.2 - 6.8e-07 28.8 0.0 0.00015 21.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGD85725.2 - 0.0049 16.8 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family TetR_C_16 PF17920.1 EGD85725.2 - 0.18 12.1 0.1 0.39 11.0 0.1 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CAP_GLY PF01302.25 EGD85726.1 - 2.1e-15 56.5 0.7 4.3e-15 55.5 0.2 1.8 2 0 0 2 2 2 1 CAP-Gly domain CLIP1_ZNF PF16641.5 EGD85726.1 - 6.7e-08 32.2 8.4 4.8e-05 23.1 0.9 2.6 2 0 0 2 2 2 2 CLIP1 zinc knuckle Fez1 PF06818.15 EGD85726.1 - 0.0017 18.8 22.7 0.05 14.1 13.8 3.0 2 1 1 3 3 3 2 Fez1 TolA_bind_tri PF16331.5 EGD85726.1 - 0.0045 17.0 1.9 0.0045 17.0 1.9 4.0 2 1 1 4 4 4 2 TolA binding protein trimerisation DUF4637 PF15470.6 EGD85726.1 - 0.0077 16.0 0.0 0.0077 16.0 0.0 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF4637) Spc7 PF08317.11 EGD85726.1 - 0.025 13.4 24.7 0.13 11.1 12.4 3.0 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 EGD85726.1 - 0.064 13.3 13.8 0.37 10.8 2.4 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 EGD85726.1 - 0.084 11.5 12.0 0.12 11.0 6.4 2.2 2 0 0 2 2 2 0 AAA domain DUF812 PF05667.11 EGD85726.1 - 0.18 10.7 21.9 0.094 11.6 13.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF812) HMMR_N PF15905.5 EGD85726.1 - 0.33 10.4 24.3 2.9 7.3 0.4 2.7 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Atg14 PF10186.9 EGD85726.1 - 0.99 8.4 17.7 0.42 9.7 5.2 3.5 2 1 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 SKA1 PF07160.12 EGD85726.1 - 1.1 9.1 9.5 1.6 8.5 0.1 3.1 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 GIT_CC PF16559.5 EGD85726.1 - 1.1 9.2 5.7 16 5.5 2.0 2.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF745 PF05335.13 EGD85726.1 - 1.4 8.6 12.7 0.17 11.6 2.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF745) Sec34 PF04136.15 EGD85726.1 - 1.4 8.8 8.4 1.5 8.7 2.9 2.3 2 0 0 2 2 2 0 Sec34-like family DUF3496 PF12001.8 EGD85726.1 - 1.7 9.1 7.9 21 5.5 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) EzrA PF06160.12 EGD85726.1 - 1.8 6.6 18.0 0.6 8.2 3.0 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA FAM76 PF16046.5 EGD85726.1 - 2.2 7.5 12.9 7.9 5.7 5.3 2.7 2 1 0 2 2 2 0 FAM76 protein NPV_P10 PF05531.12 EGD85726.1 - 2.7 8.5 12.7 52 4.4 0.1 4.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein PKcGMP_CC PF16808.5 EGD85726.1 - 3.3 7.6 27.3 0.23 11.4 2.1 4.6 5 0 0 5 5 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4349 PF14257.6 EGD85726.1 - 5.2 6.5 17.6 5.2 6.4 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) DUF16 PF01519.16 EGD85726.1 - 6 7.4 13.7 2.9 8.4 0.2 4.0 3 1 1 4 4 4 0 Protein of unknown function DUF16 Seryl_tRNA_N PF02403.22 EGD85726.1 - 9.4 6.5 13.4 22 5.3 6.2 3.5 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain 3-HAO PF06052.12 EGD85727.1 - 2.1e-56 189.8 0.0 2.5e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EGD85727.1 - 6.2e-05 22.6 0.1 0.00011 21.9 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGD85727.1 - 0.01 15.8 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain RTC_insert PF05189.13 EGD85728.1 - 2e-31 108.6 0.0 7e-31 106.8 0.0 1.9 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 EGD85728.1 - 2.9e-27 95.3 0.1 3.6e-27 95.0 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Peptidase_S9 PF00326.21 EGD85730.1 - 1.5e-50 171.7 0.0 2.6e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EGD85730.1 - 0.00013 20.7 0.0 0.054 12.2 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) DUF3189 PF11385.8 EGD85730.1 - 0.2 11.5 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) Sec63 PF02889.16 EGD85731.1 - 6.1e-165 546.6 0.1 1.2e-92 309.8 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGD85731.1 - 2.5e-46 157.6 0.1 1.6e-27 96.4 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EGD85731.1 - 2.9e-29 101.5 0.1 7.9e-29 100.1 0.1 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EGD85731.1 - 4e-22 79.0 0.0 5e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGD85731.1 - 3.1e-10 40.4 0.0 1.2e-07 32.1 0.0 3.6 2 2 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGD85731.1 - 7.1e-06 26.3 0.1 0.0033 17.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 EGD85731.1 - 0.0012 18.3 0.0 0.071 12.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 EGD85731.1 - 0.026 13.6 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 EGD85731.1 - 0.094 13.1 0.1 22 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain Ureidogly_lyase PF04115.12 EGD85733.1 - 4.9e-55 186.2 0.0 6.1e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase Catalase PF00199.19 EGD85734.1 - 3e-195 648.7 0.0 3.8e-195 648.4 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGD85734.1 - 4.2e-12 46.1 0.0 1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Rer1 PF03248.13 EGD85735.2 - 4.7e-80 267.3 4.0 5.3e-80 267.1 4.0 1.0 1 0 0 1 1 1 1 Rer1 family DUF1538 PF07556.11 EGD85735.2 - 0.11 11.7 3.3 1 8.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) ECH_1 PF00378.20 EGD85736.1 - 1.5e-78 263.6 0.1 1.8e-78 263.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGD85736.1 - 7.2e-37 127.6 0.9 9.7e-34 117.3 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase adh_short PF00106.25 EGD85738.1 - 1.4e-31 109.5 1.2 2.2e-31 108.8 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD85738.1 - 3.3e-25 89.0 1.7 4.1e-25 88.7 1.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD85738.1 - 1.4e-09 38.1 0.2 1.9e-09 37.7 0.2 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGD85738.1 - 0.0021 17.5 0.0 0.028 13.8 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGD85738.1 - 0.0023 17.4 0.1 0.0044 16.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGD85738.1 - 0.008 16.1 1.0 0.036 14.0 1.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding AIRC PF00731.20 EGD85738.1 - 0.043 13.4 0.4 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 AIR carboxylase 3Beta_HSD PF01073.19 EGD85738.1 - 0.047 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SMC_hinge PF06470.13 EGD85738.1 - 0.081 13.2 0.0 0.21 11.9 0.0 1.7 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain BTB PF00651.31 EGD85739.1 - 1.5e-15 57.3 0.1 1.2e-14 54.4 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain AnfO_nitrog PF09582.10 EGD85739.1 - 0.067 12.5 0.0 9.6 5.5 0.0 2.3 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Acetyltransf_10 PF13673.7 EGD85741.1 - 6e-10 39.1 0.0 1.8e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGD85741.1 - 9.3e-10 38.8 0.0 1.7e-09 37.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGD85741.1 - 8.3e-09 35.8 0.0 1.9e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGD85741.1 - 0.0016 18.5 0.0 0.0039 17.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGD85741.1 - 0.022 14.9 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EGD85741.1 - 0.056 13.4 0.0 0.16 12.0 0.0 1.8 1 1 1 2 2 2 0 FR47-like protein DUF3419 PF11899.8 EGD85742.2 - 2.7e-141 471.2 0.0 9.4e-80 268.6 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EGD85742.2 - 1.3e-13 51.1 0.0 4.9e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD85742.2 - 1e-11 45.3 0.0 4.4e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD85742.2 - 6e-11 42.4 0.0 2e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD85742.2 - 1.1e-10 42.1 0.0 5.9e-10 39.8 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD85742.2 - 1.8e-10 41.3 0.0 5.4e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD85742.2 - 3.2e-08 33.2 0.0 5.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGD85742.2 - 0.0002 21.2 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EGD85742.2 - 0.0039 17.2 0.0 0.0075 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGD85742.2 - 0.029 13.8 0.0 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 EGD85742.2 - 0.15 11.3 0.0 0.43 9.8 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain Lipase_3 PF01764.25 EGD85744.1 - 1.6e-05 24.8 0.0 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EGD85744.1 - 0.03 14.0 0.3 0.51 10.0 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein UPF0227 PF05728.12 EGD85744.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 EGD85744.1 - 0.24 11.1 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sel1 PF08238.12 EGD85746.1 - 6.3e-16 58.5 4.0 5e-06 27.0 0.9 3.8 4 0 0 4 4 4 3 Sel1 repeat TPR_6 PF13174.6 EGD85746.1 - 0.014 16.0 3.7 0.3 11.8 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 EGD85747.1 - 8.3e-21 74.5 0.0 2.4e-20 73.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85747.1 - 7.1e-10 38.6 0.0 0.00035 20.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Mt_ATP-synt_B PF05405.14 EGD85748.2 - 3.6e-50 169.8 9.7 4.9e-50 169.3 9.7 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ribosomal_L50 PF10501.9 EGD85748.2 - 0.014 15.5 1.0 0.058 13.5 0.0 2.3 2 0 0 2 2 2 0 Ribosomal subunit 39S CBF PF03914.17 EGD85749.1 - 1e-35 123.3 0.3 2.5e-35 122.0 0.3 1.7 1 0 0 1 1 1 1 CBF/Mak21 family DUF2115 PF09888.9 EGD85749.1 - 0.0064 17.0 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2115) PRO8NT PF08082.11 EGD85749.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain DUF4806 PF16064.5 EGD85749.1 - 0.14 12.5 0.1 0.77 10.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) GPI-anchored PF10342.9 EGD85752.2 - 6e-06 26.9 0.0 6e-06 26.9 0.0 3.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PRCC PF10253.9 EGD85752.2 - 0.37 11.6 12.4 0.48 11.2 12.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 EGD85752.2 - 2.3 7.3 20.8 2.5 7.2 20.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Mcm10 PF09332.11 EGD85752.2 - 9.5 5.5 8.9 12 5.2 8.9 1.1 1 0 0 1 1 1 0 Mcm10 replication factor DUF3632 PF12311.8 EGD85753.1 - 5.1e-34 118.2 2.1 5.1e-34 118.2 2.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) SHE3 PF17078.5 EGD85754.2 - 1.4e-08 34.8 28.5 2.3e-07 30.8 27.8 2.0 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 KASH_CCD PF14662.6 EGD85754.2 - 0.057 13.2 30.8 0.75 9.6 18.2 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 EGD85754.2 - 0.16 12.2 39.0 4.2 7.5 23.3 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TSC22 PF01166.18 EGD85754.2 - 9.5 6.6 10.1 3 8.2 1.8 3.6 2 1 1 3 3 3 0 TSC-22/dip/bun family SLS PF14611.6 EGD85755.1 - 0.069 13.0 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator EMC3_TMCO1 PF01956.16 EGD85758.2 - 3.6e-38 131.0 15.3 3.2e-36 124.6 7.4 2.1 2 0 0 2 2 2 2 Integral membrane protein EMC3/TMCO1-like SPC25 PF06703.11 EGD85759.1 - 9.1e-48 162.1 0.3 1e-47 161.9 0.3 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) THF_DHG_CYH PF00763.23 EGD85760.1 - 8.1e-26 90.6 0.0 1.3e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EGD85760.1 - 1e-13 50.9 0.0 3.6e-09 36.2 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fer2_BFD PF04324.15 EGD85760.1 - 0.071 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain ATP-synt_ab PF00006.25 EGD85761.1 - 3e-73 246.0 0.0 4.5e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EGD85761.1 - 1.7e-47 160.8 0.2 3e-47 160.1 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EGD85761.1 - 5.2e-15 55.7 2.7 1.5e-14 54.3 2.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3659 PF12396.8 EGD85761.1 - 0.14 12.1 0.6 22 5.0 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3659) DUF962 PF06127.11 EGD85762.2 - 1.2e-26 92.6 0.0 2.2e-26 91.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.17 EGD85763.1 - 4.8e-14 52.5 0.1 7.8e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EGD85763.1 - 5.9e-11 42.6 0.0 9.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 EGD85763.1 - 0.02 15.1 0.0 0.05 13.8 0.0 1.6 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 SnoaL PF07366.12 EGD85764.1 - 0.0061 16.4 0.3 0.18 11.6 0.0 2.8 2 1 0 2 2 2 1 SnoaL-like polyketide cyclase RRM_1 PF00076.22 EGD85766.1 - 1.9e-32 110.9 0.0 5.2e-18 64.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGD85766.1 - 0.097 12.8 0.0 8.3 6.6 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif AID PF18767.1 EGD85766.1 - 0.2 11.7 0.0 4.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Activation induced deaminase TPR_1 PF00515.28 EGD85767.2 - 4.7e-26 89.5 3.1 2.5e-09 36.6 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGD85767.2 - 5.3e-24 82.4 4.3 1.3e-07 31.2 0.0 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGD85767.2 - 3.3e-20 72.4 2.1 1.5e-05 25.5 0.0 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGD85767.2 - 2.5e-19 68.6 5.1 1.6e-08 34.1 0.0 5.0 4 1 1 5 5 5 3 TPR repeat TPR_14 PF13428.6 EGD85767.2 - 5.5e-18 64.1 3.3 3.1e-05 24.4 0.0 5.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGD85767.2 - 1.4e-16 59.2 0.2 6.5e-07 29.1 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGD85767.2 - 1.2e-14 53.6 2.2 0.0025 18.1 0.1 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGD85767.2 - 3.9e-14 52.9 8.9 0.00025 21.5 0.0 4.7 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 EGD85767.2 - 2.1e-10 40.8 0.9 0.0051 17.1 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGD85767.2 - 2.2e-10 39.8 2.7 0.0063 16.5 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGD85767.2 - 2.5e-10 40.5 5.4 7.7e-06 26.1 0.3 4.1 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGD85767.2 - 2.5e-10 40.3 0.8 0.0036 17.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGD85767.2 - 1.8e-07 31.3 1.5 2.1 9.1 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGD85767.2 - 7e-06 26.2 1.6 0.0022 18.2 0.1 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EGD85767.2 - 0.0002 20.7 0.7 0.26 10.5 0.5 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 EGD85767.2 - 0.0018 18.2 0.1 3.8 7.6 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat MIT PF04212.18 EGD85767.2 - 0.0042 17.1 0.4 9.2 6.4 0.1 4.3 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EGD85767.2 - 0.012 15.5 4.5 0.076 12.9 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4192 PF13830.6 EGD85767.2 - 0.045 13.8 5.3 0.062 13.4 3.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) TOM20_plant PF06552.12 EGD85767.2 - 0.058 13.1 0.2 4.3 7.0 0.0 3.0 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 NatB_MDM20 PF09797.9 EGD85767.2 - 0.09 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF1641 PF07849.11 EGD85767.2 - 0.11 12.5 0.2 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) DUF4407 PF14362.6 EGD85767.2 - 0.92 8.8 4.0 1.7 7.9 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPP_enzyme_N PF02776.18 EGD85768.1 - 2.1e-44 151.2 0.2 4.2e-44 150.2 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGD85768.1 - 2.3e-34 118.1 0.0 4.1e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EGD85768.1 - 5.7e-18 65.2 0.0 1.4e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain B12-binding PF02310.19 EGD85768.1 - 0.0077 16.3 0.2 0.03 14.4 0.2 2.0 1 0 0 1 1 1 1 B12 binding domain CO_dh PF02552.16 EGD85768.1 - 0.037 13.8 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit ERO1 PF04137.15 EGD85769.1 - 1.5e-134 448.7 0.0 2.1e-134 448.2 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) FliT PF05400.13 EGD85769.1 - 0.34 11.7 1.1 18 6.2 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein FliT GST_C PF00043.25 EGD85770.1 - 2.1e-08 34.2 0.0 3.2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGD85770.1 - 4.6e-08 33.3 0.0 7.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGD85770.1 - 0.00042 20.7 0.0 0.00081 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGD85770.1 - 0.0051 17.1 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGD85770.1 - 0.028 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EGD85770.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Peroxin-13_N PF04088.13 EGD85771.1 - 1.3e-53 181.1 0.1 2.5e-53 180.3 0.1 1.5 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EGD85771.1 - 6.7e-09 35.3 0.0 1.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGD85771.1 - 2.3e-07 30.3 0.0 4.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGD85771.1 - 9.8e-06 25.3 0.1 1.7e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 EGD85771.1 - 0.21 12.1 0.0 0.37 11.2 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain Aminotran_5 PF00266.19 EGD85772.2 - 1.1e-26 93.7 0.0 1.8e-26 93.0 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class-V APG6 PF04111.12 EGD85773.1 - 4.8e-73 244.9 0.0 7.4e-73 244.3 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EGD85773.1 - 2.2e-38 131.8 7.4 3.6e-38 131.1 7.4 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Rpr2 PF04032.16 EGD85773.1 - 0.11 12.7 0.2 0.7 10.2 0.0 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Sds3 PF08598.11 EGD85773.1 - 0.53 10.3 4.9 0.7 9.9 4.0 1.7 1 1 0 1 1 1 0 Sds3-like Jnk-SapK_ap_N PF09744.9 EGD85773.1 - 3.1 8.0 8.7 6.3 7.0 8.7 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Scm3 PF10384.9 EGD85774.1 - 2.5e-22 78.4 0.1 4.7e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-bind_6 PF13921.6 EGD85774.1 - 1.4e-05 25.2 3.4 0.06 13.6 1.4 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGD85774.1 - 3.3e-05 24.0 0.2 1.2 9.4 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain PALP PF00291.25 EGD85775.1 - 1e-60 205.7 2.3 2.1e-60 204.7 2.3 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.17 EGD85776.2 - 4.7e-40 137.9 0.0 6.4e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pathogen_betaC1 PF09593.10 EGD85776.2 - 0.11 12.4 0.3 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein Pal1 PF08316.11 EGD85777.1 - 5.7e-08 33.6 0.1 1.1e-07 32.7 0.1 1.5 1 0 0 1 1 1 1 Pal1 cell morphology protein Terpene_synth_C PF03936.16 EGD85778.2 - 6.3e-08 32.3 0.3 1.1e-07 31.5 0.3 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain HVSL PF09749.9 EGD85779.1 - 8.7e-86 287.2 0.0 1.1e-85 286.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3807 PF12720.7 EGD85780.1 - 1.6e-40 139.4 2.9 2e-40 139.0 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) STN1_2 PF09170.10 EGD85780.1 - 0.071 13.3 0.5 0.091 13.0 0.5 1.1 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 EPL1 PF10513.9 EGD85780.1 - 0.62 10.4 7.3 0.23 11.9 5.1 1.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Pex14_N PF04695.13 EGD85780.1 - 1 10.0 6.4 1.6 9.3 6.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMF_DNA_bd PF12329.8 EGD85781.1 - 0.03 14.3 2.2 0.03 14.3 2.2 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4355 PF14265.6 EGD85781.1 - 0.53 10.5 6.9 0.75 10.0 6.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) PY_rept_46 PF09689.10 EGD85781.1 - 8.6 7.0 8.1 7.4 7.2 0.5 2.8 1 1 1 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) SAS4 PF15460.6 EGD85784.1 - 1.6e-30 105.1 5.2 1.6e-30 105.1 5.2 2.2 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 DNA_pol_phi PF04931.13 EGD85784.1 - 0.18 9.9 23.2 0.28 9.3 23.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 EGD85784.1 - 0.26 9.8 23.1 0.41 9.2 23.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 EGD85784.1 - 0.56 8.4 28.9 0.84 7.8 28.9 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGD85784.1 - 0.94 7.7 20.8 1.8 6.8 20.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 EGD85784.1 - 1.1 8.2 23.8 2.7 6.9 23.8 1.6 1 0 0 1 1 1 0 Paf1 BT1 PF03092.16 EGD85784.1 - 1.3 7.2 4.2 2 6.6 4.2 1.2 1 0 0 1 1 1 0 BT1 family RNA_pol_3_Rpc31 PF11705.8 EGD85784.1 - 2.2 8.5 26.8 0.25 11.6 21.4 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CobT PF06213.12 EGD85784.1 - 2.2 7.6 22.3 6 6.2 22.3 1.7 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 EGD85784.1 - 3.8 6.7 19.6 7 5.9 19.6 1.3 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 EGD85784.1 - 6.7 5.8 13.3 13 4.9 13.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PX PF00787.24 EGD85785.1 - 2.3e-14 53.3 0.0 3.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 PX domain Spaetzle PF16077.5 EGD85786.1 - 0.043 14.4 7.5 2 9.0 3.7 2.3 2 0 0 2 2 2 0 Spaetzle Brix PF04427.18 EGD85787.2 - 9.7e-22 78.0 0.0 1.4e-21 77.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain SH3_9 PF14604.6 EGD85788.1 - 6.5e-30 102.8 3.6 3.8e-14 52.3 0.4 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EGD85788.1 - 1.8e-29 101.0 4.2 1.8e-14 53.0 0.4 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGD85788.1 - 6.5e-16 57.8 0.0 2.6e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 EGD85788.1 - 7.4e-16 58.0 0.0 1.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Dynamin_M PF01031.20 EGD85789.2 - 2.4e-111 371.6 0.0 4.1e-111 370.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 EGD85789.2 - 4.2e-32 110.2 0.8 1.2e-31 108.7 0.8 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain zf-C2H2 PF00096.26 EGD85790.2 - 0.0029 18.0 5.9 0.0029 18.0 5.9 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type C1_4 PF07975.12 EGD85790.2 - 0.06 13.6 0.3 0.16 12.2 0.3 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_4 PF13894.6 EGD85790.2 - 1.3 10.1 18.3 0.082 13.8 4.9 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger YjbR PF04237.13 EGD85793.2 - 0.012 16.1 0.0 0.24 12.0 0.0 2.3 1 1 1 2 2 2 0 YjbR AAA PF00004.29 EGD85794.2 - 6.8e-49 165.7 0.0 6.2e-43 146.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD85794.2 - 1.3e-06 28.1 3.0 0.0011 18.7 0.0 3.2 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 EGD85794.2 - 6.1e-05 23.5 0.0 0.023 15.1 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EGD85794.2 - 0.00014 21.6 0.0 0.00042 20.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EGD85794.2 - 0.00042 19.5 0.0 0.00096 18.3 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 EGD85794.2 - 0.001 19.4 0.0 0.016 15.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 EGD85794.2 - 0.0028 17.8 0.0 0.0084 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGD85794.2 - 0.0032 17.7 0.0 0.049 13.9 0.0 3.0 4 1 1 5 5 3 1 AAA domain PhoH PF02562.16 EGD85794.2 - 0.0055 16.2 0.0 0.2 11.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein TIP49 PF06068.13 EGD85794.2 - 0.0061 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGD85794.2 - 0.0074 16.5 0.0 0.45 10.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGD85794.2 - 0.0081 15.9 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 EGD85794.2 - 0.0082 15.7 0.0 0.043 13.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.10 EGD85794.2 - 0.022 14.7 0.2 0.55 10.3 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 EGD85794.2 - 0.023 14.1 0.1 0.051 13.0 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGD85794.2 - 0.025 15.1 0.6 0.12 12.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 EGD85794.2 - 0.031 14.3 0.0 0.13 12.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 EGD85794.2 - 0.032 13.6 0.0 0.082 12.2 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 EGD85794.2 - 0.042 13.3 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EGD85794.2 - 0.044 13.8 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Kinase-PolyVal PF18762.1 EGD85794.2 - 0.083 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins AAA_28 PF13521.6 EGD85794.2 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.6 EGD85795.1 - 1.1e-46 157.0 15.8 2.1e-18 66.4 2.4 5.9 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 EGD85795.1 - 3.6e-43 144.3 20.6 1.3e-09 37.6 0.2 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGD85795.1 - 4.5e-13 48.2 16.7 0.0078 16.3 0.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGD85795.1 - 5.4e-12 44.8 16.4 0.0022 17.9 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGD85795.1 - 3.3e-10 39.3 15.6 4.1e-05 23.2 0.2 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGD85795.1 - 2.8e-08 34.3 15.8 0.16 12.6 0.1 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGD85795.1 - 1.6e-07 31.0 18.1 0.23 11.8 0.2 6.8 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGD85795.1 - 2.9e-06 26.9 4.6 0.0021 17.5 2.3 3.2 2 1 1 3 3 3 2 MalT-like TPR region ANAPC3 PF12895.7 EGD85795.1 - 0.0019 18.4 5.5 0.023 14.9 1.5 3.9 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EGD85795.1 - 0.0021 18.7 10.3 10 7.2 0.1 5.8 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGD85795.1 - 0.0021 17.7 7.3 3.3 7.5 0.2 4.8 4 0 0 4 4 4 1 TPR repeat TPR_4 PF07721.14 EGD85795.1 - 0.0023 18.4 0.3 17 6.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGD85795.1 - 0.012 16.1 15.9 3.7 8.1 0.0 4.8 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGD85795.1 - 0.087 13.2 10.5 1 9.9 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGD85795.1 - 0.2 11.7 1.7 0.67 10.0 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EGD85795.1 - 0.23 11.5 14.3 2.2 8.4 0.1 4.9 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EGD85795.1 - 3.3 8.5 10.6 5.2 7.9 0.1 5.2 7 0 0 7 7 5 0 Tetratricopeptide repeat Questin_oxidase PF14027.6 EGD85796.1 - 1.6e-82 277.8 0.2 1.9e-82 277.5 0.2 1.0 1 0 0 1 1 1 1 Questin oxidase-like HECT_2 PF09814.9 EGD85798.1 - 2.4e-114 382.1 0.9 2.7e-114 381.9 0.9 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding PI-PLC-X PF00388.19 EGD85801.2 - 4e-60 201.6 0.0 6.2e-60 201.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGD85801.2 - 5.1e-41 139.6 0.0 1e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain DPPIV_N PF00930.21 EGD85802.2 - 1.6e-110 369.2 0.6 2.3e-110 368.7 0.6 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EGD85802.2 - 7.4e-31 107.3 1.2 1.6e-30 106.2 1.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGD85802.2 - 0.00018 21.2 0.2 0.00046 19.9 0.2 1.7 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PBP1_TM PF14812.6 EGD85802.2 - 0.00034 20.9 0.0 0.001 19.4 0.0 1.7 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal AXE1 PF05448.12 EGD85802.2 - 0.12 11.1 0.0 0.55 8.8 0.0 1.9 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 EGD85802.2 - 0.14 12.7 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_2 PF00890.24 EGD85803.1 - 2.9e-125 418.6 4.0 3.7e-125 418.3 4.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EGD85803.1 - 1.5e-43 147.9 1.5 2.2e-43 147.3 1.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 EGD85803.1 - 5.2e-06 25.8 1.0 0.014 14.5 2.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EGD85803.1 - 5.2e-06 25.9 0.2 0.00095 18.5 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGD85803.1 - 7.7e-05 22.1 0.2 0.055 12.7 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EGD85803.1 - 0.0036 16.6 0.7 0.0085 15.4 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EGD85803.1 - 0.043 13.4 2.3 0.23 11.0 2.3 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EGD85803.1 - 0.17 10.5 1.0 0.94 8.1 0.7 2.3 3 0 0 3 3 3 0 HI0933-like protein AAA PF00004.29 EGD85804.1 - 6.1e-41 139.9 0.0 1.1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD85804.1 - 3.3e-05 23.6 0.0 7.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EGD85804.1 - 7.2e-05 23.1 0.0 0.0073 16.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EGD85804.1 - 0.00011 22.2 0.1 0.00043 20.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGD85804.1 - 0.00021 21.4 0.0 0.00069 19.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGD85804.1 - 0.00035 21.0 0.3 0.0076 16.7 0.1 2.4 2 1 1 3 3 2 1 AAA ATPase domain DUF815 PF05673.13 EGD85804.1 - 0.0023 17.1 0.0 0.0042 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EGD85804.1 - 0.0083 15.9 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGD85804.1 - 0.016 15.5 0.1 0.063 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGD85804.1 - 0.048 13.2 0.0 0.16 11.4 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGD85804.1 - 0.05 13.8 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGD85804.1 - 0.06 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EGD85804.1 - 0.067 12.9 0.1 0.6 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EGD85804.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGD85804.1 - 0.095 12.4 0.0 0.24 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGD85804.1 - 0.12 13.0 0.0 0.49 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGD85804.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.24 EGD85805.1 - 8.6e-147 489.7 13.4 9.7e-147 489.5 13.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Beta-APP PF03494.13 EGD85806.1 - 0.25 11.2 0.7 0.47 10.3 0.7 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) zf-GRF PF06839.12 EGD85806.1 - 0.58 10.3 4.9 0.67 10.1 3.3 1.9 2 0 0 2 2 2 0 GRF zinc finger TMEM154 PF15102.6 EGD85806.1 - 4.5 7.2 5.1 71 3.3 5.0 2.4 1 1 0 1 1 1 0 TMEM154 protein family Ribosomal_L37 PF08561.10 EGD85807.1 - 7.5e-44 149.1 3.3 1.1e-43 148.6 3.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 AAA_lid_10 PF17872.1 EGD85807.1 - 0.039 14.1 0.1 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA lid domain PGA2 PF07543.12 EGD85807.1 - 4.3 7.3 6.7 6.5 6.7 1.0 2.1 1 1 1 2 2 2 0 Protein trafficking PGA2 NMT1 PF09084.11 EGD85808.1 - 1.8e-64 217.7 0.1 7.6e-43 147.0 0.0 2.1 1 1 1 2 2 2 2 NMT1/THI5 like NMT1_2 PF13379.6 EGD85808.1 - 1.1e-05 25.3 0.0 0.28 10.9 0.0 3.1 3 0 0 3 3 3 2 NMT1-like family Plasmodium_Vir PF05795.11 EGD85809.2 - 2.7 7.3 10.5 0.12 11.8 1.0 2.2 1 1 0 2 2 2 0 Plasmodium vivax Vir protein Alg6_Alg8 PF03155.15 EGD85810.2 - 8.8e-26 90.9 7.2 1e-25 90.7 7.2 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family RRM_1 PF00076.22 EGD85811.1 - 1.9e-35 120.5 0.0 3.7e-17 61.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGD85811.1 - 0.00022 21.3 0.0 0.12 12.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Alg6_Alg8 PF03155.15 EGD85812.2 - 1.3e-86 291.6 17.8 4.5e-48 164.4 7.0 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family GT87 PF09594.10 EGD85812.2 - 7.4e-07 29.1 9.7 7.4e-07 29.1 9.7 2.4 2 2 0 2 2 2 1 Glycosyltransferase family 87 COX17 PF05051.13 EGD85813.2 - 3.4e-20 72.1 6.1 5.3e-20 71.5 6.1 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EGD85813.2 - 0.029 14.4 2.6 0.099 12.7 0.0 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like LRR_6 PF13516.6 EGD85814.1 - 2e-10 39.9 2.9 0.061 13.4 0.0 7.4 8 0 0 8 8 8 1 Leucine Rich repeat LRR_4 PF12799.7 EGD85814.1 - 3.2e-06 27.4 6.3 1.6 9.3 0.0 5.8 4 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGD85814.1 - 0.023 15.2 7.5 59 4.8 0.1 6.3 7 0 0 7 7 7 0 Leucine Rich Repeat BPL_N PF09825.9 EGD85814.1 - 0.42 9.7 3.6 0.63 9.0 3.6 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Drc1-Sld2 PF11719.8 EGD85814.1 - 0.97 8.9 14.8 1.3 8.4 14.8 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.12 EGD85814.1 - 1.8 6.7 23.8 2.3 6.3 23.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EGD85814.1 - 5.4 6.3 25.4 7.4 5.9 25.4 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 EGD85814.1 - 6.2 6.0 15.3 9.3 5.5 15.3 1.2 1 0 0 1 1 1 0 NOA36 protein AAA_11 PF13086.6 EGD85814.1 - 6.5 6.4 7.3 11 5.8 7.3 1.3 1 0 0 1 1 1 0 AAA domain BUD22 PF09073.10 EGD85814.1 - 7.2 5.8 20.6 10 5.3 20.6 1.2 1 0 0 1 1 1 0 BUD22 MBOAT_2 PF13813.6 EGD85815.2 - 1.2e-16 60.7 0.2 3e-16 59.4 0.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Sec10 PF07393.11 EGD85816.1 - 2.4e-234 779.9 0.0 2.9e-234 779.7 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 MarR_2 PF12802.7 EGD85816.1 - 0.079 12.9 0.3 1.5 8.8 0.0 2.9 3 0 0 3 3 3 0 MarR family TFIIS_M PF07500.14 EGD85819.1 - 1.1e-29 103.1 1.8 1.1e-29 103.1 1.8 1.9 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EGD85819.1 - 1.9e-18 66.0 4.7 3e-18 65.4 4.7 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EGD85819.1 - 7.1e-13 48.4 0.4 1.5e-12 47.3 0.4 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 EGD85819.1 - 0.092 12.4 0.1 0.092 12.4 0.1 1.9 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-LITAF-like PF10601.9 EGD85819.1 - 0.2 12.0 1.9 0.39 11.0 1.9 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain BTAD PF03704.17 EGD85820.1 - 0.041 14.3 0.0 0.08 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain FRQ PF09421.10 EGD85824.2 - 0.0016 16.6 2.3 0.0019 16.3 2.3 1.1 1 0 0 1 1 1 1 Frequency clock protein SPT6_acidic PF14632.6 EGD85824.2 - 0.008 16.7 4.7 0.008 16.7 4.7 1.7 2 0 0 2 2 2 1 Acidic N-terminal SPT6 CIAPIN1 PF05093.13 EGD85824.2 - 0.016 15.7 0.1 0.023 15.2 0.1 1.3 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Cnd2 PF05786.14 EGD85824.2 - 0.053 12.2 5.5 0.064 11.9 5.5 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Ferlin_C PF16165.5 EGD85824.2 - 0.092 12.7 2.9 0.11 12.4 2.9 1.2 1 0 0 1 1 1 0 Ferlin C-terminus GEN1_C PF18380.1 EGD85824.2 - 0.12 13.3 3.2 0.25 12.3 3.2 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain SRP72 PF08492.12 EGD85824.2 - 0.12 12.8 7.7 9.8 6.7 6.9 2.2 2 0 0 2 2 2 0 SRP72 RNA-binding domain DUF4710 PF15828.5 EGD85824.2 - 1.4 9.1 10.1 2.7 8.2 10.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) DUF1682 PF07946.14 EGD85824.2 - 1.5 7.9 9.3 2 7.5 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TMEM208_SND2 PF05620.11 EGD85824.2 - 5.9 6.6 5.2 9 6.0 5.2 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Sortilin-Vps10 PF15902.5 EGD85829.1 - 5.9e-286 948.2 2.2 1.5e-153 511.8 0.6 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EGD85829.1 - 1.2e-93 312.2 22.9 1.1e-47 162.5 9.1 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EGD85829.1 - 3.2e-08 32.4 28.9 0.44 10.7 0.1 9.4 10 0 0 10 10 10 4 BNR/Asp-box repeat BNR_2 PF13088.6 EGD85829.1 - 0.00014 21.3 0.2 7.2 5.8 0.0 5.0 4 1 0 4 4 4 2 BNR repeat-like domain CHB_HEX_C PF03174.13 EGD85829.1 - 0.02 14.9 0.4 2.6 8.1 0.0 3.2 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Transp_cyt_pur PF02133.15 EGD85830.2 - 2.9e-42 145.0 5.3 3.7e-42 144.6 5.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin dCMP_cyt_deam_1 PF00383.23 EGD85831.1 - 3.7e-15 55.6 1.5 4.6e-15 55.3 1.5 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EGD85831.1 - 3.6e-08 33.7 3.8 3.2e-07 30.6 0.4 2.0 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EGD85831.1 - 2.3e-05 24.1 3.2 0.00062 19.4 0.3 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Mito_carr PF00153.27 EGD85832.1 - 2.4e-65 216.5 0.5 3.9e-22 78.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.14 EGD85833.2 - 2.1e-21 76.3 29.6 2.2e-21 76.2 29.6 1.0 1 0 0 1 1 1 1 Cgr1 family Vfa1 PF08432.10 EGD85833.2 - 2.3 8.5 12.5 2.7 8.3 12.5 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ndufs5 PF10200.9 EGD85833.2 - 4.5 7.6 9.4 11 6.4 9.4 1.6 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Joubert PF15392.6 EGD85833.2 - 9.8 5.8 18.7 11 5.6 18.7 1.1 1 0 0 1 1 1 0 Joubert syndrome-associated BLOC1_2 PF10046.9 EGD85834.1 - 0.014 15.7 0.5 0.032 14.5 0.4 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YqfD PF06898.11 EGD85834.1 - 4.9 5.9 8.7 0.39 9.5 2.5 2.0 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD SUI1 PF01253.22 EGD85835.1 - 9.5e-24 83.7 0.2 2e-23 82.7 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 R3H-assoc PF13902.6 EGD85835.1 - 0.027 14.8 1.0 0.054 13.9 1.0 1.4 1 0 0 1 1 1 0 R3H-associated N-terminal domain SRP14 PF02290.15 EGD85835.1 - 0.04 14.3 0.3 0.07 13.5 0.3 1.4 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Img2 PF05046.14 EGD85835.1 - 0.065 13.5 0.5 0.12 12.7 0.1 1.7 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) DUF1752 PF08550.10 EGD85838.1 - 2.8e-10 39.9 2.8 8.3e-10 38.3 2.8 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ELMO_CED12 PF04727.13 EGD85839.1 - 2.9e-51 174.1 0.1 5e-51 173.3 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 EGD85839.1 - 7.1e-32 110.8 0.0 1.4e-31 109.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 EGD85839.1 - 1.3e-15 57.7 0.0 3.6e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Rad17 PF03215.15 EGD85840.1 - 2.6e-26 92.7 0.0 4.4e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EGD85840.1 - 5.3e-05 23.7 0.1 0.00024 21.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGD85840.1 - 0.0022 18.0 0.0 0.0073 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EGD85840.1 - 0.0024 17.6 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGD85840.1 - 0.003 16.7 0.0 0.0064 15.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.6 EGD85840.1 - 0.0055 17.0 0.1 0.0055 17.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGD85840.1 - 0.0076 16.8 4.5 0.05 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGD85840.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGD85840.1 - 0.018 15.4 0.1 0.061 13.7 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 EGD85840.1 - 0.023 13.7 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 EGD85840.1 - 0.032 14.4 0.1 0.12 12.6 0.1 2.0 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 EGD85840.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase TsaE PF02367.17 EGD85840.1 - 0.078 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EGD85840.1 - 0.1 12.4 1.7 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGD85840.1 - 0.13 12.8 3.7 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain PGA2 PF07543.12 EGD85840.1 - 0.22 11.5 7.0 9.5 6.2 0.0 2.9 2 0 0 2 2 2 0 Protein trafficking PGA2 UAA PF08449.11 EGD85841.1 - 6.4e-83 278.4 11.6 1.3e-82 277.4 11.6 1.5 1 1 0 1 1 1 1 UAA transporter family TMEM100 PF16311.5 EGD85841.1 - 0.092 12.3 0.4 0.24 11.0 0.4 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 MFS_5 PF05631.14 EGD85842.2 - 7.1e-61 206.1 3.5 1e-60 205.6 3.5 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EGD85842.2 - 7.5e-21 74.4 26.2 2.5e-19 69.4 17.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD85842.2 - 8.3e-13 48.0 2.4 8.3e-13 48.0 2.4 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 EGD85842.2 - 2e-07 29.9 5.6 2e-07 29.9 5.6 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 EGD85842.2 - 0.00059 18.8 0.0 0.0017 17.3 0.0 1.9 1 1 0 1 1 1 1 MFS_1 like family MFS_4 PF06779.14 EGD85842.2 - 0.00068 19.0 6.9 0.0016 17.8 6.9 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Crystall PF00030.19 EGD85843.1 - 0.053 13.7 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 Beta/Gamma crystallin Hydrolase_6 PF13344.6 EGD85844.1 - 9.5e-21 73.8 0.0 2.4e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGD85844.1 - 3.2e-17 62.3 0.0 7e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EGD85844.1 - 0.023 14.8 0.0 0.36 10.9 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGD85844.1 - 0.026 14.8 0.0 1.6 9.0 0.0 3.0 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Apt1 PF10351.9 EGD85844.1 - 0.035 13.0 0.0 0.035 13.0 0.0 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain HAD PF12710.7 EGD85844.1 - 0.068 13.6 0.0 1.9 8.9 0.0 2.7 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EGD85844.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Aldo_ket_red PF00248.21 EGD85845.2 - 1.2e-23 83.8 0.0 1.5e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TnpV PF14198.6 EGD85845.2 - 0.018 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV DUF3818 PF12825.7 EGD85847.2 - 3.8e-129 430.5 6.2 5.9e-129 429.9 6.2 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PX PF00787.24 EGD85847.2 - 1.6e-11 44.2 0.0 3.5e-10 39.9 0.0 2.8 2 1 0 2 2 2 1 PX domain Glyco_hydro_8 PF01270.17 EGD85847.2 - 0.042 12.7 0.0 0.081 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 NPV_P10 PF05531.12 EGD85847.2 - 0.073 13.5 0.2 0.21 12.1 0.2 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Met_10 PF02475.16 EGD85850.2 - 6.8e-67 225.1 0.1 8.5e-67 224.8 0.1 1.1 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 EGD85850.2 - 0.037 13.2 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase RNA_pol_Rpb4 PF03874.16 EGD85851.1 - 2.9e-22 79.3 3.0 4.1e-22 78.8 3.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cut8 PF08559.10 EGD85851.1 - 0.0034 17.1 0.3 0.0037 16.9 0.3 1.2 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein AMP-binding PF00501.28 EGD85852.2 - 4.5e-50 170.5 0.0 5.6e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD85852.2 - 1.7e-06 28.9 0.0 3.7e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SR-25 PF10500.9 EGD85853.1 - 0.43 10.1 11.9 0.58 9.7 11.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3123 PF11321.8 EGD85853.1 - 3 8.6 8.3 5.7 7.6 8.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3123) RhoGAP PF00620.27 EGD85854.2 - 3.4e-16 59.4 0.1 6.3e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EGD85854.2 - 1.9e-05 24.8 3.8 1.9e-05 24.8 3.8 1.7 2 0 0 2 2 2 1 LIM domain Nbl1_Borealin_N PF10444.9 EGD85855.1 - 4.3e-19 67.9 4.0 8e-19 67.0 4.0 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.6 EGD85856.1 - 1.3e-23 83.6 0.0 3.2e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EGD85856.1 - 0.00018 21.4 0.1 0.00025 20.9 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 EGD85856.1 - 0.014 15.3 0.3 0.041 13.8 0.3 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Sybindin PF04099.12 EGD85857.2 - 1.3e-46 158.0 0.0 1.8e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EGD85857.2 - 1.1e-06 28.8 0.0 1.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region UQ_con PF00179.26 EGD85859.2 - 1.3e-13 50.7 0.1 4.5e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGD85859.2 - 7.9e-05 22.4 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic E2 family B FGE-sulfatase PF03781.16 EGD85862.1 - 9.5e-31 107.3 0.1 1.5e-30 106.6 0.1 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_25 PF13649.6 EGD85862.1 - 1.2e-06 29.2 0.0 9.3e-05 23.1 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.7 EGD85862.1 - 3e-06 27.8 0.3 6.6e-06 26.6 0.3 1.6 1 0 0 1 1 1 1 DinB superfamily Methyltransf_11 PF08241.12 EGD85862.1 - 9.9e-05 22.9 0.0 0.0013 19.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD85862.1 - 0.0013 18.5 0.0 0.68 9.7 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGD85862.1 - 0.098 13.4 0.0 0.41 11.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Gln-synt_C PF00120.24 EGD85863.1 - 2.2e-47 161.8 0.0 1.6e-46 158.9 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain IDO PF01231.18 EGD85864.1 - 6e-34 117.6 0.0 8.7e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase PRORP PF16953.5 EGD85864.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-only RNase P 3Beta_HSD PF01073.19 EGD85866.1 - 7.6e-46 156.4 0.0 2.2e-45 154.8 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGD85866.1 - 1.2e-15 57.6 0.7 1.7e-14 53.9 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGD85866.1 - 3e-10 39.7 0.0 4.1e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EGD85866.1 - 4.8e-10 39.3 0.0 0.00013 21.5 0.0 3.3 2 1 0 3 3 3 3 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGD85866.1 - 0.00034 19.8 0.0 0.00082 18.6 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGD85866.1 - 0.057 13.3 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding Pkinase PF00069.25 EGD85868.1 - 7.8e-60 202.5 0.0 4e-39 134.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85868.1 - 6e-29 101.1 0.0 5.5e-21 75.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EGD85868.1 - 8.7e-13 48.4 0.0 1.7e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EGD85868.1 - 5.8e-08 32.4 0.0 1.2e-05 24.8 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EGD85868.1 - 0.00013 21.9 0.5 0.0055 16.7 0.2 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EGD85868.1 - 0.0031 16.9 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 EGD85868.1 - 0.0038 17.4 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain Haspin_kinase PF12330.8 EGD85868.1 - 0.016 14.1 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain PAS PF00989.25 EGD85868.1 - 0.042 13.9 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold RIO1 PF01163.22 EGD85868.1 - 0.099 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 EGD85868.1 - 0.17 10.9 0.1 0.3 10.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 eIF-3_zeta PF05091.12 EGD85869.1 - 3.1e-201 669.9 0.0 3.7e-201 669.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) bZIP_1 PF00170.21 EGD85870.2 - 0.0044 17.1 12.7 0.085 13.0 12.7 2.1 1 1 0 1 1 1 1 bZIP transcription factor Med9 PF07544.13 EGD85870.2 - 0.0081 16.2 0.6 0.0081 16.2 0.6 2.2 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 TMCO5 PF14992.6 EGD85870.2 - 0.026 14.1 2.1 0.033 13.8 2.1 1.1 1 0 0 1 1 1 0 TMCO5 family bZIP_2 PF07716.15 EGD85870.2 - 0.28 11.3 12.2 0.054 13.6 4.4 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Aminopep PF10023.9 EGD85870.2 - 0.59 9.4 2.9 0.77 9.1 2.9 1.1 1 0 0 1 1 1 0 Putative aminopeptidase TEX13 PF15186.6 EGD85870.2 - 1.1 8.9 5.4 1.5 8.5 5.4 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family F-box-like PF12937.7 EGD85871.1 - 0.0013 18.6 0.1 0.0013 18.6 0.1 2.0 2 0 0 2 2 2 1 F-box-like NOA36 PF06524.12 EGD85871.1 - 0.018 14.4 7.1 0.025 13.9 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein F-box PF00646.33 EGD85871.1 - 0.024 14.5 1.1 0.077 12.9 0.5 2.3 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 EGD85871.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 F-box Mrx7 PF10906.8 EGD85871.1 - 0.1 12.9 0.0 0.35 11.2 0.0 1.9 1 0 0 1 1 1 0 MIOREX complex component 7 Herpes_gE PF02480.16 EGD85871.1 - 2.5 6.8 4.1 3.5 6.3 4.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Nop14 PF04147.12 EGD85871.1 - 4 5.5 9.9 5 5.2 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3546 PF12066.8 EGD85874.1 - 1.4e-31 108.9 0.7 1.4e-31 108.9 0.7 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 EGD85874.1 - 9.7e-12 44.5 0.1 2.4e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 EGD85874.1 - 3.6e-10 40.6 3.8 9.9e-10 39.1 3.3 1.8 1 1 0 1 1 1 1 Arsenite-resistance protein 2 CCDC71L PF15374.6 EGD85875.2 - 0.002 17.5 0.9 0.0022 17.4 0.9 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 71L CBFB_NFYA PF02045.15 EGD85875.2 - 6.2 7.5 7.2 1.7 9.3 3.6 1.8 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Kinesin PF00225.23 EGD85876.1 - 9e-112 373.3 0.0 1.3e-111 372.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 EGD85876.1 - 2.4e-45 155.0 0.0 6.6e-45 153.5 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 EGD85876.1 - 1.1e-37 130.0 12.4 2.1e-37 129.0 2.8 3.3 3 1 0 3 3 3 1 Kinesin-associated Microtub_bd PF16796.5 EGD85876.1 - 4.1e-24 85.2 0.0 1.1e-23 83.9 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 EGD85876.1 - 1.1e-07 32.1 0.2 4.8e-07 30.1 0.2 2.2 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 EGD85876.1 - 3.5e-06 27.3 0.2 2.1e-05 24.8 0.1 2.5 2 0 0 2 2 2 1 FHA domain PH PF00169.29 EGD85876.1 - 0.00013 22.4 0.0 0.00044 20.7 0.0 1.9 2 0 0 2 2 2 1 PH domain Cytomega_UL20A PF05984.12 EGD85876.1 - 1.7 9.0 8.5 0.18 12.1 0.8 2.6 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein UPF0242 PF06785.11 EGD85876.1 - 2.2 8.4 7.1 0.42 10.7 0.8 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus 3-dmu-9_3-mt PF06983.13 EGD85877.1 - 4.7e-39 133.5 0.1 6.5e-39 133.1 0.1 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase DSX_dimer PF08828.10 EGD85877.1 - 0.0098 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Doublesex dimerisation domain Chalcone_2 PF16035.5 EGD85879.1 - 0.15 11.9 0.1 0.21 11.4 0.1 1.2 1 0 0 1 1 1 0 Chalcone isomerase like Cohesin_HEAT PF12765.7 EGD85879.1 - 0.51 10.7 7.7 27 5.2 0.2 4.1 3 1 1 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Fungal_trans_2 PF11951.8 EGD85881.2 - 2.6e-15 56.1 0.8 3.2e-15 55.8 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain CompInhib_SCIN PF11546.8 EGD85881.2 - 0.1 12.7 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN DUF2742 PF10888.8 EGD85881.2 - 0.14 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) LuxC PF05893.14 EGD85882.1 - 0.0019 17.3 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) NTP_transf_5 PF14907.6 EGD85882.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.4 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase AbiEii PF08843.11 EGD85882.1 - 0.033 14.1 0.0 0.074 13.0 0.0 1.5 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system zf-C2H2 PF00096.26 EGD85883.2 - 6e-06 26.4 11.2 0.0035 17.7 0.1 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD85883.2 - 0.043 14.7 15.8 1.3 10.1 0.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 EGD85883.2 - 0.052 14.2 6.5 0.17 12.5 0.0 3.3 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 EGD85883.2 - 0.061 13.7 0.0 74 3.9 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ham1p_like PF01725.16 EGD85884.1 - 1.7e-50 171.6 0.0 1.9e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family UAA PF08449.11 EGD85885.1 - 7.7e-29 100.8 7.0 9.3e-29 100.6 7.0 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 EGD85885.1 - 0.00061 19.2 0.1 0.00061 19.2 0.1 2.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family Phosphodiest PF01663.22 EGD85886.1 - 2.6e-86 290.5 0.1 3.3e-86 290.1 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGD85886.1 - 0.00056 19.4 0.0 0.48 9.8 0.0 2.3 1 1 1 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 EGD85886.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 EGD85886.1 - 0.1 12.7 0.0 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 PglZ domain HNH_2 PF13391.6 EGD85887.1 - 3.8e-11 42.9 0.0 3.9e-09 36.5 0.0 3.5 4 0 0 4 4 4 1 HNH endonuclease TMPIT PF07851.13 EGD85887.1 - 0.25 10.6 2.0 6.1 6.0 1.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein ATP-synt_E PF05680.12 EGD85887.1 - 1.8 8.9 5.8 8.8 6.7 1.3 3.6 5 0 0 5 5 5 0 ATP synthase E chain PHP_C PF13263.6 EGD85888.2 - 0.038 13.7 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 PHP-associated Herpes_US9 PF06072.11 EGD85891.1 - 0.13 12.1 1.6 0.3 11.0 1.6 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 SNARE PF05739.19 EGD85891.1 - 0.76 9.8 7.2 1.6 8.8 7.2 1.4 1 0 0 1 1 1 0 SNARE domain Prominin PF05478.11 EGD85891.1 - 8.9 4.1 9.1 13 3.6 9.1 1.1 1 0 0 1 1 1 0 Prominin Fic PF02661.18 EGD85892.2 - 6.1e-09 36.7 0.1 9.7e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Fic/DOC family HLH PF00010.26 EGD85894.2 - 1.6e-15 56.8 0.8 5.5e-15 55.1 0.6 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Leu_zip PF15294.6 EGD85894.2 - 8.5 5.8 11.6 0.76 9.2 3.8 2.2 2 0 0 2 2 2 0 Leucine zipper IDO PF01231.18 EGD85895.2 - 7.3e-06 25.0 0.0 1.1e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Ofd1_CTDD PF10637.9 EGD85897.1 - 5.6e-94 314.3 0.1 8e-92 307.2 0.2 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EGD85897.1 - 5.8e-25 87.8 0.0 2.5e-24 85.7 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EGD85897.1 - 7.2e-14 52.5 0.0 1.7e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.23 EGD85898.1 - 5.8e-15 55.9 0.0 1.2e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family COesterase PF00135.28 EGD85900.2 - 7e-77 259.4 0.0 9.9e-77 258.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGD85900.2 - 6.3e-07 29.5 0.1 5.8e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGD85900.2 - 0.14 11.7 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family p450 PF00067.22 EGD85902.1 - 9.6e-67 225.7 0.0 1.3e-66 225.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.22 EGD85902.1 - 0.023 14.7 0.5 0.046 13.7 0.5 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit FAD_binding_4 PF01565.23 EGD85903.1 - 3.1e-34 117.7 7.1 1.2e-33 115.8 6.8 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EGD85903.1 - 0.0095 16.0 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DRMBL PF07522.14 EGD85905.1 - 3.7e-33 114.0 0.0 7.7e-33 113.0 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EGD85905.1 - 3.5e-05 23.4 0.0 0.00013 21.5 0.0 1.9 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGD85905.1 - 0.031 14.3 0.2 0.066 13.2 0.2 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily LSM PF01423.22 EGD85906.1 - 3.9e-18 64.9 0.8 5.1e-18 64.5 0.8 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGD85906.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Hfq protein DUF402 PF04167.13 EGD85906.1 - 0.054 13.7 0.4 0.074 13.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF402) Methyltransf_11 PF08241.12 EGD85907.1 - 4.7e-07 30.4 0.0 1e-06 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD85907.1 - 0.071 13.8 0.0 0.2 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain zf-BED PF02892.15 EGD85909.1 - 0.0011 18.9 5.5 0.31 11.1 0.3 2.6 2 0 0 2 2 2 2 BED zinc finger SH3BGR PF04908.15 EGD85910.1 - 0.00033 20.8 2.9 0.0032 17.6 0.0 3.1 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 EGD85910.1 - 0.15 12.3 0.2 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin Hamartin PF04388.12 EGD85910.1 - 0.46 9.1 13.2 0.52 8.9 13.2 1.0 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.25 EGD85911.2 - 4.7e-09 36.0 0.0 6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGD85911.2 - 0.0012 18.8 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGD85911.2 - 0.012 14.5 0.1 0.016 14.0 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGD85911.2 - 0.032 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribul_P_3_epim PF00834.19 EGD85912.1 - 2e-61 206.9 0.0 2.8e-60 203.1 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Melibiase PF02065.18 EGD85912.1 - 0.007 15.3 0.1 0.29 10.0 0.0 2.2 2 0 0 2 2 2 2 Melibiase ThiG PF05690.14 EGD85912.1 - 0.1 11.9 0.5 0.15 11.4 0.5 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG zf-C2H2_4 PF13894.6 EGD85913.1 - 0.45 11.5 12.9 0.35 11.8 0.4 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGD85913.1 - 0.48 11.0 14.5 2.5 8.7 0.3 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type ABC2_membrane PF01061.24 EGD85916.2 - 1.7e-85 285.7 63.9 8.3e-45 152.8 19.8 3.0 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 EGD85916.2 - 7e-34 115.6 11.1 6.9e-32 109.2 0.1 3.9 4 0 0 4 4 4 2 CDR ABC transporter ABC_tran PF00005.27 EGD85916.2 - 5.6e-17 62.5 0.0 1.3e-16 61.4 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGD85916.2 - 4.7e-06 25.9 53.0 0.0051 16.0 19.8 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 EGD85916.2 - 4.5e-05 23.1 0.0 8.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGD85916.2 - 0.00041 20.5 0.0 0.00083 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGD85916.2 - 0.0005 20.0 0.0 0.0013 18.6 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGD85916.2 - 0.0015 19.0 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGD85916.2 - 0.004 17.7 0.0 0.0086 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EGD85916.2 - 0.0053 16.6 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGD85916.2 - 0.01 15.5 0.3 0.032 14.0 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain SMC_N PF02463.19 EGD85916.2 - 0.065 12.7 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 EGD85916.2 - 0.12 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MS_channel PF00924.18 EGD85918.1 - 1.1e-24 87.1 2.8 2.4e-24 86.0 2.8 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 EGD85918.1 - 2.9e-05 23.4 0.1 7.4e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EGD85918.1 - 0.00023 20.5 0.2 0.00052 19.4 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGD85918.1 - 0.00053 19.7 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EGD85918.1 - 0.0052 17.2 0.4 0.013 15.9 0.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair Tubulin PF00091.25 EGD85919.1 - 5.1e-65 219.4 0.0 6.7e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGD85919.1 - 2e-44 150.8 0.0 3.1e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGD85919.1 - 0.00037 20.2 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Mito_carr PF00153.27 EGD85920.1 - 5.9e-64 212.0 3.1 3.3e-20 71.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGD85920.1 - 0.06 12.5 2.2 0.85 8.7 0.0 3.3 4 0 0 4 4 4 0 Gammaproteobacterial serine protease TauD PF02668.16 EGD85921.1 - 1.6e-43 149.5 0.0 2.2e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EGD85921.1 - 2.2e-06 28.2 0.0 5.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EGD85921.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 CsiD Glutaredoxin PF00462.24 EGD85922.1 - 1.1e-18 67.2 0.0 1.2e-16 60.7 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EGD85922.1 - 1.3e-12 47.6 0.0 3.1e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGD85922.1 - 0.00042 20.6 0.0 0.052 13.9 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGD85922.1 - 0.0045 17.4 0.0 0.056 13.9 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGD85922.1 - 0.018 14.4 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family KIAA1430 PF13879.6 EGD85925.1 - 0.023 15.4 0.6 0.023 15.4 0.6 2.7 3 1 0 3 3 3 0 KIAA1430 homologue SlyX PF04102.12 EGD85925.1 - 0.23 12.1 1.8 3.7 8.2 0.2 3.1 3 0 0 3 3 3 0 SlyX Beta_elim_lyase PF01212.21 EGD85926.1 - 3e-66 223.7 0.0 3.7e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase CN_hydrolase PF00795.22 EGD85927.1 - 4.1e-43 147.6 0.1 5.3e-43 147.2 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pkinase PF00069.25 EGD85929.1 - 1.4e-65 221.3 0.0 3.4e-65 220.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD85929.1 - 1.8e-33 116.0 0.0 3e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGD85929.1 - 3.9e-09 36.7 1.0 3.8e-08 33.5 0.3 2.7 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 EGD85929.1 - 0.00031 21.0 0.0 0.00074 19.8 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RIO1 PF01163.22 EGD85929.1 - 0.02 14.5 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EGD85929.1 - 0.039 13.3 0.0 0.12 11.6 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGD85929.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGD85929.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M28 PF04389.17 EGD85930.2 - 1.3e-18 67.5 0.0 1.9e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EGD85930.2 - 8.4e-11 41.7 0.6 1.4e-09 37.8 0.4 2.8 2 1 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EGD85930.2 - 0.037 13.7 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 PRONE PF03759.13 EGD85930.2 - 0.048 12.5 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) Glyco_transf_34 PF05637.12 EGD85933.1 - 4.8e-63 213.1 0.0 7.2e-63 212.5 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family GPR15L PF15854.5 EGD85933.1 - 0.056 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 NDUFB10 PF10249.9 EGD85934.2 - 0.01 16.3 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 BRO1 PF03097.18 EGD85935.1 - 2.2e-13 49.8 1.1 5e-13 48.6 1.1 1.5 1 1 0 1 1 1 1 BRO1-like domain Bromo_TP PF07524.13 EGD85937.1 - 5.5e-10 39.1 0.0 9.7e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EGD85937.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DNA_photolyase PF00875.18 EGD85942.2 - 1.3e-39 135.9 0.0 2.4e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.14 EGD85942.2 - 0.31 10.5 2.6 0.34 10.3 0.5 2.0 2 0 0 2 2 2 0 FAD binding domain of DNA photolyase GFA PF04828.14 EGD85943.1 - 1.2e-15 57.6 0.8 1.7e-15 57.1 0.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Tmemb_9 PF05434.11 EGD85943.1 - 0.53 10.2 3.9 6.6 6.6 0.0 2.1 2 0 0 2 2 2 0 TMEM9 APH PF01636.23 EGD85944.2 - 8.4e-13 48.8 0.0 1.4e-11 44.8 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGD85944.2 - 0.0075 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EGD85944.2 - 0.062 12.1 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Polysacc_syn_2C PF08485.10 EGD85944.2 - 0.16 11.7 0.1 0.42 10.4 0.1 1.7 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal adh_short PF00106.25 EGD85945.1 - 7.2e-11 41.9 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD85945.1 - 9.2e-08 32.2 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EGD85945.1 - 3.1e-06 26.9 0.0 4.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peptidase_M36 PF02128.15 EGD85946.1 - 3.8e-160 533.1 2.6 4.7e-160 532.8 2.6 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGD85946.1 - 2.4e-17 62.5 3.1 5.2e-17 61.4 3.1 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M14 PF00246.24 EGD85947.2 - 1.3e-14 54.8 0.0 1.8e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EGD85947.2 - 0.011 14.8 0.0 0.023 13.8 0.0 1.5 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 EGD85947.2 - 0.038 13.4 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Aldo_ket_red PF00248.21 EGD85948.1 - 1.3e-49 169.0 0.0 2e-49 168.3 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_1c PF00749.21 EGD85949.1 - 4.4e-98 328.0 0.0 8.3e-98 327.1 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGD85949.1 - 2.3e-32 112.2 0.0 3.8e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 EGD85949.1 - 0.0025 17.8 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGD85949.1 - 0.0033 17.6 0.0 0.02 15.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 EGD85949.1 - 0.041 13.2 0.0 0.093 12.1 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C PF00043.25 EGD85949.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Acetyltransf_7 PF13508.7 EGD85950.2 - 2.1e-16 60.1 0.0 7.5e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGD85950.2 - 1.6e-14 54.1 0.0 1.9e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGD85950.2 - 1.2e-12 47.9 0.0 3.4e-06 27.0 0.0 2.9 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGD85950.2 - 1.4e-06 28.4 0.1 0.0032 17.5 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD85950.2 - 9.8e-05 22.3 0.1 0.014 15.3 0.0 2.5 2 0 0 2 2 2 1 FR47-like protein Glyco_hydro_3_C PF01915.22 EGD85950.2 - 0.00029 20.9 0.0 0.0005 20.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_CG PF14542.6 EGD85950.2 - 0.0017 18.5 0.1 0.23 11.6 0.0 2.5 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Toprim PF01751.22 EGD85950.2 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Toprim domain ATP11 PF06644.11 EGD85951.1 - 4.1e-99 331.8 0.0 4.8e-99 331.5 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Hydrolase_4 PF12146.8 EGD85952.2 - 1.5e-14 53.9 0.1 2.3e-13 50.0 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGD85952.2 - 5.1e-09 36.1 0.0 9.7e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD85952.2 - 1.8e-05 25.4 0.0 2.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 EGD85952.2 - 0.00067 19.6 0.0 0.0045 16.9 0.0 2.1 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 EGD85952.2 - 0.0012 17.6 0.1 0.028 13.1 0.0 2.3 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EGD85952.2 - 0.0016 18.4 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 EGD85952.2 - 0.0082 15.8 0.0 0.036 13.7 0.0 1.8 1 1 1 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 EGD85952.2 - 0.013 15.0 0.0 0.23 11.0 0.0 2.5 3 0 0 3 3 3 0 Dienelactone hydrolase family PGAP1 PF07819.13 EGD85952.2 - 0.014 15.2 0.2 0.2 11.3 0.2 2.2 1 1 0 1 1 1 0 PGAP1-like protein DUF818 PF05677.12 EGD85952.2 - 0.021 13.8 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) LIDHydrolase PF10230.9 EGD85952.2 - 0.021 14.4 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 EGD85952.2 - 0.091 12.6 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 EGD85952.2 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Acyl_transf_2 PF02273.15 EGD85952.2 - 0.13 11.4 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Acyl transferase DUF2974 PF11187.8 EGD85952.2 - 0.14 11.7 0.1 0.3 10.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S28 PF05577.12 EGD85952.2 - 0.28 9.9 0.0 0.44 9.3 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Proteasome PF00227.26 EGD85954.1 - 6.9e-48 162.7 0.3 7.9e-48 162.5 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit RabGAP-TBC PF00566.18 EGD85955.1 - 5.9e-28 98.0 0.0 1.4e-27 96.8 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EGD85955.1 - 8.5e-08 30.9 0.3 8.5e-08 30.9 0.3 1.9 2 0 0 2 2 2 1 SBE2, cell-wall formation Telomerase_RBD PF12009.8 EGD85956.2 - 1.3e-48 164.5 0.0 3.2e-48 163.2 0.0 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 EGD85956.2 - 9.4e-12 44.9 0.0 2.2e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) EAV_GS PF01309.18 EGD85956.2 - 0.022 14.4 0.2 0.053 13.1 0.2 1.6 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein RhoGEF PF00621.20 EGD85957.2 - 4.6e-37 128.0 0.1 2.3e-36 125.8 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain Peptidase_C48 PF02902.19 EGD85958.2 - 2.1e-13 50.6 0.8 1.1e-12 48.2 0.8 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PrpF PF04303.13 EGD85959.2 - 2e-72 244.2 0.2 2.1e-72 244.1 0.2 1.0 1 0 0 1 1 1 1 PrpF protein tRNA-synt_1d PF00750.19 EGD85960.2 - 1.1e-44 152.8 2.5 1.5e-44 152.3 2.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EGD85960.2 - 2.2e-24 85.9 0.1 5.8e-24 84.6 0.1 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain WRC PF08879.10 EGD85962.1 - 0.012 15.3 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 WRC DAP3 PF10236.9 EGD85963.2 - 8.6e-86 287.9 0.0 1.4e-85 287.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 EGD85963.2 - 0.1 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 EGD85963.2 - 0.12 11.6 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RRS1 PF04939.12 EGD85964.1 - 3.3e-55 186.4 1.9 4.1e-55 186.1 1.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Ribosomal_L41 PF05162.13 EGD85964.1 - 0.58 10.3 11.4 0.072 13.2 5.7 2.3 2 0 0 2 2 2 0 Ribosomal protein L41 RhoGAP PF00620.27 EGD85965.2 - 1.1e-27 96.7 0.0 1.9e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.21 EGD85967.2 - 1.1e-49 165.9 5.0 2.9e-11 42.9 0.1 5.8 5 1 1 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EGD85967.2 - 1.9e-06 27.2 0.0 0.022 13.8 0.0 3.8 2 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EGD85967.2 - 0.02 14.0 0.1 0.21 10.7 0.0 2.2 1 1 2 3 3 3 0 Squalene-hopene cyclase C-terminal domain zf-C2H2_2 PF12756.7 EGD85968.2 - 0.052 13.9 0.3 0.49 10.7 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) MutS_V PF00488.21 EGD85969.2 - 6.6e-74 248.0 0.1 9.9e-74 247.4 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.18 EGD85969.2 - 3.8e-06 27.2 0.2 8.4e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_III PF05192.18 EGD85969.2 - 0.00013 22.2 0.1 0.00029 21.1 0.1 1.6 1 0 0 1 1 1 1 MutS domain III Ribosomal_S28e PF01200.18 EGD85970.1 - 5.6e-33 112.7 0.4 6.2e-33 112.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.18 EGD85971.2 - 8.5e-54 181.8 0.0 1.2e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EGD85971.2 - 6.3e-29 99.9 0.5 1.3e-28 99.0 0.5 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EGD85971.2 - 0.01 15.8 0.0 0.035 14.0 0.0 1.8 1 1 0 1 1 1 0 NMT1/THI5 like MCM PF00493.23 EGD85973.2 - 5.9e-103 342.8 0.0 8.7e-103 342.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGD85973.2 - 1.4e-31 108.9 0.1 2.4e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGD85973.2 - 1e-21 77.2 0.6 3.5e-21 75.4 0.6 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGD85973.2 - 2.7e-07 30.2 0.0 4.2e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 EGD85973.2 - 7.5e-06 26.5 0.0 2.5e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 EGD85973.2 - 1.9e-05 24.7 0.0 4.8e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 EGD85973.2 - 0.035 14.7 0.1 0.15 12.7 0.1 2.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal AAA_lid_2 PF17863.1 EGD85973.2 - 0.038 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA lid domain AAA_3 PF07726.11 EGD85973.2 - 0.05 13.5 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) EGF_CA PF07645.15 EGD85975.1 - 8e-06 26.0 5.4 8e-06 26.0 5.4 1.7 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.7 EGD85975.1 - 0.0025 18.0 4.7 0.0025 18.0 4.7 2.0 2 1 0 2 2 2 1 EGF domain Plasmod_Pvs28 PF06247.11 EGD85975.1 - 0.0028 17.9 2.1 0.0078 16.5 2.1 1.7 1 0 0 1 1 1 1 Pvs28 EGF domain FXa_inhibition PF14670.6 EGD85975.1 - 0.0032 17.7 3.5 0.0032 17.7 3.5 2.5 2 1 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 EGD85975.1 - 0.0034 17.3 0.1 0.0034 17.3 0.1 2.2 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.27 EGD85975.1 - 0.0079 16.5 5.2 0.0079 16.5 5.2 2.0 2 1 0 2 2 2 1 EGF-like domain hEGF PF12661.7 EGD85975.1 - 5.8 7.7 10.0 0.83 10.4 0.8 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF F-box PF00646.33 EGD85976.1 - 0.017 15.0 0.1 0.075 12.9 0.1 2.1 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EGD85976.1 - 0.09 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 EGD85977.2 - 5.3e-27 94.7 19.1 1.6e-23 83.2 14.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGD85977.2 - 1.5e-06 26.8 4.5 2.2e-06 26.2 1.6 2.2 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Mucin15 PF15672.5 EGD85977.2 - 0.045 13.2 3.1 1.3 8.4 0.1 2.3 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 AMP-binding PF00501.28 EGD85983.1 - 1.8e-92 310.1 0.0 2.2e-92 309.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD85983.1 - 1.4e-16 61.3 0.0 6.7e-16 59.0 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CMAS PF02353.20 EGD85984.1 - 7.7e-61 205.8 0.0 9.8e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGD85984.1 - 9.9e-09 35.2 0.0 1.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD85984.1 - 2.4e-08 34.6 0.0 5.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD85984.1 - 3.4e-08 34.0 0.0 1.1e-07 32.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD85984.1 - 0.00062 20.5 0.0 0.0013 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EGD85984.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 EGD85984.1 - 0.12 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 EGD85984.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EGD85984.1 - 0.2 11.7 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Mitofilin PF09731.9 EGD85985.2 - 0.18 10.6 17.3 0.27 10.0 17.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Phage_CRI PF05144.14 EGD85985.2 - 5.3 6.3 6.8 15 4.8 0.1 2.2 1 1 1 2 2 2 0 Phage replication protein CRI Tropomyosin_1 PF12718.7 EGD85986.1 - 4e-50 169.7 34.7 4.9e-50 169.4 34.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EGD85986.1 - 7.3e-10 38.6 36.0 3.8e-06 26.5 16.1 2.1 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.9 EGD85986.1 - 3.5e-05 24.0 25.0 5.9e-05 23.2 10.7 3.1 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 EGD85986.1 - 0.00019 20.4 34.3 0.043 12.7 17.3 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EGD85986.1 - 0.00074 19.6 34.1 0.0023 18.0 6.1 3.1 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 EGD85986.1 - 0.00075 19.5 21.2 0.014 15.4 8.8 2.1 1 1 1 2 2 2 2 Laminin Domain II DUF1664 PF07889.12 EGD85986.1 - 0.0018 18.3 19.2 0.0068 16.4 3.9 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Med9 PF07544.13 EGD85986.1 - 0.002 18.2 5.9 0.002 18.2 5.9 3.2 2 1 1 3 3 3 2 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.6 EGD85986.1 - 0.0032 16.8 33.8 0.031 13.6 26.8 2.4 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DHR10 PF18595.1 EGD85986.1 - 0.0062 16.6 39.3 0.008 16.2 18.3 2.7 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain ATG16 PF08614.11 EGD85986.1 - 0.0097 16.1 33.5 0.44 10.8 25.0 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 EGD85986.1 - 0.013 15.9 35.2 0.19 12.1 15.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ADIP PF11559.8 EGD85986.1 - 0.013 15.5 33.9 0.38 10.8 11.8 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 EGD85986.1 - 0.021 14.0 31.3 0.16 11.2 6.4 2.0 1 1 1 2 2 2 0 Myosin-like coiled-coil protein ERM PF00769.19 EGD85986.1 - 0.038 13.8 40.0 0.086 12.6 18.6 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family FlaC_arch PF05377.11 EGD85986.1 - 0.14 12.6 21.6 0.62 10.5 0.3 4.3 2 1 3 5 5 5 0 Flagella accessory protein C (FlaC) MAD PF05557.13 EGD85986.1 - 0.14 10.5 34.4 0.27 9.5 34.4 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein CEP63 PF17045.5 EGD85986.1 - 0.15 12.0 29.6 1.2 8.9 29.6 1.9 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa HOOK PF05622.12 EGD85986.1 - 0.16 10.1 27.5 0.23 9.6 27.5 1.3 1 0 0 1 1 1 0 HOOK protein Atg14 PF10186.9 EGD85986.1 - 0.21 10.6 28.8 0.57 9.2 12.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 EGD85986.1 - 0.3 10.9 30.8 0.12 12.2 9.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.9 EGD85986.1 - 0.33 11.1 35.4 0.37 11.0 25.2 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 EGD85986.1 - 0.37 11.5 28.4 1.4 9.6 10.9 3.3 1 1 2 3 3 3 0 SlyX Fib_alpha PF08702.10 EGD85986.1 - 0.46 10.7 22.8 0.68 10.1 3.0 3.0 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 EGD85986.1 - 0.59 10.2 36.5 0.045 13.8 12.8 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding CLZ PF16526.5 EGD85986.1 - 0.63 10.4 25.2 0.42 11.0 3.2 3.6 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 EGD85986.1 - 0.74 10.2 24.1 1.1 9.7 1.1 3.4 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BST2 PF16716.5 EGD85986.1 - 0.81 10.3 29.7 2.4 8.8 11.7 3.3 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 DUF3450 PF11932.8 EGD85986.1 - 0.83 8.9 32.3 0.4 9.9 12.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 EGD85986.1 - 0.9 10.0 30.6 0.53 10.7 25.8 1.9 1 1 1 2 2 2 0 Fez1 Laminin_I PF06008.14 EGD85986.1 - 0.94 9.1 28.2 1.4 8.6 9.4 2.9 1 1 2 3 3 3 0 Laminin Domain I Uso1_p115_C PF04871.13 EGD85986.1 - 0.97 9.8 35.8 0.88 9.9 16.1 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3584 PF12128.8 EGD85986.1 - 1 6.8 30.0 1.1 6.7 30.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 EGD85986.1 - 1.1 7.8 28.7 5 5.6 28.7 2.0 1 1 0 1 1 1 0 AAA domain XhlA PF10779.9 EGD85986.1 - 1.2 9.4 27.0 0.55 10.5 3.0 4.2 1 1 3 4 4 4 0 Haemolysin XhlA KxDL PF10241.9 EGD85986.1 - 1.8 8.9 22.5 0.39 11.0 0.7 4.0 1 1 2 4 4 4 0 Uncharacterized conserved protein FapA PF03961.13 EGD85986.1 - 2.4 6.7 27.9 0.49 9.0 11.6 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A PI3K_P85_iSH2 PF16454.5 EGD85986.1 - 2.7 7.6 29.6 9.2 5.8 23.8 2.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PspB PF06667.12 EGD85986.1 - 2.7 8.1 17.6 0.42 10.7 3.8 3.7 1 1 2 3 3 3 0 Phage shock protein B APG6_N PF17675.1 EGD85986.1 - 2.8 8.5 40.5 1.5e+02 2.9 22.8 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region JIP_LZII PF16471.5 EGD85986.1 - 2.8 8.2 27.3 0.24 11.6 3.1 4.2 2 1 3 5 5 5 0 JNK-interacting protein leucine zipper II DUF5082 PF16888.5 EGD85986.1 - 3.4 8.0 25.9 2.4 8.5 2.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) PRKG1_interact PF15898.5 EGD85986.1 - 3.5 8.6 32.1 5.4 8.0 16.8 3.0 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Fmp27_SW PF10305.9 EGD85986.1 - 3.5 8.4 9.0 0.21 12.3 1.6 2.4 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Cep57_MT_bd PF06657.13 EGD85986.1 - 3.7 8.1 23.2 0.069 13.6 4.4 3.6 1 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.8 EGD85986.1 - 3.8 7.8 33.0 36 4.6 15.3 2.9 1 1 1 2 2 1 0 TATA element modulatory factor 1 TATA binding YjcZ PF13990.6 EGD85986.1 - 4.2 6.7 11.8 6 6.2 11.8 1.3 1 0 0 1 1 1 0 YjcZ-like protein DUF16 PF01519.16 EGD85986.1 - 4.3 7.9 24.6 1.8 9.1 8.8 2.7 1 1 1 2 2 1 0 Protein of unknown function DUF16 FUSC PF04632.12 EGD85986.1 - 4.3 5.7 9.9 5.1 5.5 9.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 EGD85986.1 - 4.4 7.4 33.7 11 6.1 12.7 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF745 PF05335.13 EGD85986.1 - 5.6 6.6 25.4 5.9 6.6 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) YabA PF06156.13 EGD85986.1 - 5.9 7.6 25.7 8.5 7.1 10.3 3.1 1 1 2 3 3 3 0 Initiation control protein YabA DUF2203 PF09969.9 EGD85986.1 - 5.9 7.6 22.6 1.8e+04 -7.9 22.4 3.0 1 1 0 1 1 0 0 Uncharacterized conserved protein (DUF2203) DivIC PF04977.15 EGD85986.1 - 6.1 6.7 35.9 0.18 11.6 2.9 4.5 1 1 3 4 4 4 0 Septum formation initiator MS_channel PF00924.18 EGD85986.1 - 6.4 6.3 5.3 2.8 7.5 2.9 1.6 1 1 1 2 2 2 0 Mechanosensitive ion channel KELK PF15796.5 EGD85986.1 - 6.5 7.3 35.4 17 5.9 15.3 3.7 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase V_ATPase_I PF01496.19 EGD85986.1 - 7.6 4.3 24.3 1.9 6.3 9.2 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.12 EGD85986.1 - 7.7 6.6 39.7 2.1 8.4 9.2 2.5 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein She9_MDM33 PF05546.11 EGD85986.1 - 8.2 6.2 24.9 22 4.8 8.8 2.6 1 1 1 2 2 2 0 She9 / Mdm33 family Nop25 PF09805.9 EGD85987.1 - 6.4e-21 75.3 5.0 5.7e-12 46.3 3.9 4.1 2 2 2 4 4 4 2 Nucleolar protein 12 (25kDa) DUF4604 PF15377.6 EGD85987.1 - 0.08 13.4 24.8 0.12 12.8 24.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) EIIBC-GUT_N PF03612.14 EGD85987.1 - 5.7 6.6 8.1 4.8 6.9 5.9 2.0 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Nop53 PF07767.11 EGD85987.1 - 8 5.7 42.2 6.6 6.0 29.3 2.1 1 1 1 2 2 2 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 EGD85987.1 - 8.3 4.6 31.9 1.2 7.4 22.6 2.0 2 0 0 2 2 2 0 CDC45-like protein ATP-synt_S1 PF05827.12 EGD85988.1 - 3.9e-05 23.5 0.0 7.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) PDGLE PF13190.6 EGD85988.1 - 0.06 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 PDGLE domain Sin_N PF04801.13 EGD85990.2 - 1.2e-27 97.2 0.6 4.8e-27 95.2 0.6 1.8 1 1 0 1 1 1 1 Sin-like protein conserved region RNA_pol PF00940.19 EGD85991.1 - 9.4e-184 611.0 0.0 1.4e-183 610.5 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EGD85991.1 - 7e-93 311.7 0.9 1e-92 311.1 0.9 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal YaiA PF16362.5 EGD85991.1 - 0.16 12.0 0.7 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 YaiA protein Ketoacyl-synt_C PF02801.22 EGD85994.2 - 0.0095 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PLAC PF08686.11 EGD85994.2 - 0.78 10.6 12.5 0.44 11.4 7.2 2.4 3 0 0 3 3 3 0 PLAC (protease and lacunin) domain Frankia_peptide PF14407.6 EGD85995.2 - 0.028 14.4 0.0 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. WD40 PF00400.32 EGD85996.1 - 3.8e-08 33.8 5.8 0.02 15.8 0.0 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD85996.1 - 6.5e-06 26.4 0.1 0.11 12.8 0.0 4.4 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EGD85996.1 - 0.00048 20.1 0.0 0.00093 19.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.7 EGD85996.1 - 0.00054 20.6 0.6 0.0077 16.9 0.1 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGD85996.1 - 0.0073 16.0 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EGD85996.1 - 0.015 14.8 0.2 0.055 13.0 0.2 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) 6PF2K PF01591.18 EGD85996.1 - 0.026 13.8 0.0 0.088 12.1 0.0 1.9 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Nbas_N PF15492.6 EGD85996.1 - 0.046 13.1 0.0 0.16 11.3 0.0 1.9 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal AAA_22 PF13401.6 EGD85996.1 - 0.081 13.2 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGD85996.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Fructosamin_kin PF03881.14 EGD85997.2 - 1.8e-29 102.9 0.0 2.3e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EGD85997.2 - 0.029 14.3 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Aldo_ket_red PF00248.21 EGD85998.1 - 2.6e-44 151.6 0.0 1e-43 149.6 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family DUF92 PF01940.16 EGD86000.2 - 5e-75 251.9 7.0 5.5e-75 251.8 7.0 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 TPR_2 PF07719.17 EGD86003.2 - 0.00031 20.6 0.0 0.072 13.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3138 PF11336.8 EGD86004.1 - 0.32 9.6 5.1 0.31 9.6 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FGE-sulfatase PF03781.16 EGD86006.2 - 4.9e-20 72.2 4.3 5.3e-19 68.8 4.3 2.0 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 XFP_C PF09363.10 EGD86007.2 - 0.11 12.0 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 XFP C-terminal domain Aldedh PF00171.22 EGD86008.2 - 2.8e-122 408.5 0.2 3.4e-122 408.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGD86008.2 - 0.00023 20.3 0.0 0.001 18.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) TFIIA_gamma_N PF02268.16 EGD86011.2 - 9.8e-25 86.3 0.1 1.2e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Hexokinase_1 PF00349.21 EGD86013.2 - 1.8e-61 207.5 0.0 2.5e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EGD86013.2 - 5.2e-43 147.2 0.0 1.7e-42 145.5 0.0 1.8 1 1 0 1 1 1 1 Hexokinase RNA_pol_Rpb1_2 PF00623.20 EGD86013.2 - 0.14 12.4 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 GILT PF03227.16 EGD86014.1 - 7.3e-15 55.1 1.9 5.6e-14 52.3 1.2 2.5 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) MFS_1 PF07690.16 EGD86016.1 - 2.8e-32 112.0 25.4 2.8e-32 112.0 25.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily GCP_N_terminal PF17681.1 EGD86017.1 - 1.8e-29 103.3 0.0 8.3e-29 101.2 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGD86017.1 - 6.7e-25 88.2 0.1 1.1e-24 87.4 0.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal ThiF PF00899.21 EGD86018.2 - 6.1e-114 379.4 0.0 1.2e-74 250.8 0.0 2.2 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGD86018.2 - 1.9e-96 322.9 1.0 8.2e-96 320.8 0.7 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EGD86018.2 - 2.5e-30 104.5 0.1 5.7e-30 103.3 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EGD86018.2 - 9.1e-29 100.0 0.0 2.1e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 EGD86018.2 - 2.1e-23 82.3 1.3 2.1e-23 82.3 1.3 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 EGD86018.2 - 0.04 14.3 0.0 0.31 11.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding GST_N_2 PF13409.6 EGD86019.2 - 1.2e-22 80.0 0.0 3e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGD86019.2 - 2.1e-13 50.1 0.0 4.1e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGD86019.2 - 5.9e-06 26.6 0.1 0.00034 21.0 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGD86019.2 - 5.2e-05 23.4 0.0 0.00014 22.0 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.27 EGD86020.2 - 8.8e-63 208.3 4.6 5.3e-21 74.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EGD86020.2 - 2.9e-21 75.7 7.1 1.2e-11 44.9 1.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGD86020.2 - 1.4e-17 61.8 7.9 7.4e-06 25.1 1.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 EGD86020.2 - 1.2e-16 59.4 6.7 2.2e-05 23.7 1.4 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGD86020.2 - 2.7e-16 58.0 10.9 3.4e-05 23.4 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGD86020.2 - 1.3e-10 40.9 4.3 2.9e-05 23.8 0.2 3.6 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGD86020.2 - 1.9e-08 34.6 0.2 9.1e-05 22.7 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EGD86020.2 - 0.0014 18.4 0.4 2.7 7.9 0.1 2.7 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 EGD86020.2 - 0.0052 16.7 3.4 0.53 10.3 0.5 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Arch_fla_DE PF04659.13 EGD86020.2 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal flagella protein Cyclin_N PF00134.23 EGD86021.2 - 4.3e-09 36.2 0.1 6.3e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EGD86021.2 - 0.043 14.2 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 Cyclin C-terminal domain DUF4452 PF14618.6 EGD86022.2 - 7.5e-52 175.6 7.1 7.5e-52 175.6 7.1 2.8 1 1 1 2 2 1 1 Domain of unknown function (DUF4452) Zip PF02535.22 EGD86022.2 - 0.016 14.4 11.1 0.02 14.2 11.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter AF-4 PF05110.13 EGD86022.2 - 0.61 8.1 23.1 0.89 7.6 23.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Spem1 PF15670.5 EGD86022.2 - 0.66 9.5 12.1 1 8.9 12.1 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 Ecl1 PF12855.7 EGD86022.2 - 2.3 9.4 28.8 0.78 10.9 24.2 2.0 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins SPX PF03105.19 EGD86022.2 - 2.4 8.0 15.3 3.2 7.6 15.3 1.2 1 0 0 1 1 1 0 SPX domain PAT1 PF09770.9 EGD86022.2 - 4.4 5.4 16.9 5.8 5.1 16.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 EGD86022.2 - 4.5 5.9 9.0 5.6 5.6 9.0 1.1 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 EGD86022.2 - 6.1 3.8 15.4 7.8 3.5 15.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1387 PF07139.11 EGD86022.2 - 9.3 5.9 10.8 17 5.0 10.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Neur_chan_memb PF02932.16 EGD86022.2 - 9.5 6.2 8.1 16 5.4 8.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Lin-8 PF03353.15 EGD86022.2 - 9.5 5.7 10.8 15 5.1 10.8 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDRT4 PF15213.6 EGD86024.1 - 0.048 14.3 1.0 0.066 13.8 0.8 1.3 1 1 0 1 1 1 0 CMT1A duplicated region transcript 4 protein AMP-binding_C_2 PF14535.6 EGD86024.1 - 0.071 13.4 1.3 0.097 13.0 1.3 1.2 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain F-box-like PF12937.7 EGD86025.1 - 2.1e-06 27.5 0.6 6.7e-06 25.9 0.6 1.9 1 0 0 1 1 1 1 F-box-like AAA_12 PF13087.6 EGD86026.1 - 5.9e-39 133.8 0.2 1.8e-38 132.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EGD86026.1 - 1.3e-19 71.0 0.0 1.3e-19 71.0 0.0 3.1 4 1 0 4 4 4 1 AAA domain DUF2075 PF09848.9 EGD86026.1 - 5e-08 32.6 0.2 0.00064 19.1 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EGD86026.1 - 9.2e-08 32.5 0.0 7.3e-07 29.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain zf-CCCH_4 PF18044.1 EGD86026.1 - 7.4e-06 25.6 2.2 3.4e-05 23.5 2.2 2.3 1 0 0 1 1 1 1 CCCH-type zinc finger AAA_30 PF13604.6 EGD86026.1 - 7.7e-06 25.8 0.2 0.00088 19.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 EGD86026.1 - 0.0031 17.6 0.0 0.012 15.6 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit COG5 PF10392.9 EGD86026.1 - 0.088 13.0 0.0 9.7 6.4 0.0 2.9 3 0 0 3 3 3 0 Golgi transport complex subunit 5 UvrD_C_2 PF13538.6 EGD86026.1 - 0.17 11.7 0.0 0.43 10.5 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.21 EGD86026.1 - 0.2 11.0 2.0 0.84 9.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI zf_CCCH_4 PF18345.1 EGD86026.1 - 0.33 11.1 9.0 0.016 15.3 2.0 2.8 2 0 0 2 2 1 0 Zinc finger domain DUF745 PF05335.13 EGD86026.1 - 3 7.5 7.1 8.1 6.1 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Chal_sti_synt_C PF02797.15 EGD86027.1 - 6.2e-19 68.5 0.0 1.1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 EGD86027.1 - 1.7e-15 57.1 0.1 2.8e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III_C PF08541.10 EGD86027.1 - 0.00018 21.6 0.0 0.0018 18.4 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.12 EGD86027.1 - 0.051 12.9 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein SNARE PF05739.19 EGD86030.2 - 5.8e-10 39.0 0.1 9e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 SNARE domain DUF1676 PF07898.13 EGD86030.2 - 0.012 15.6 0.0 0.022 14.8 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Synaptobrevin PF00957.21 EGD86030.2 - 4.6 7.1 4.8 3.3 7.6 0.4 2.6 3 0 0 3 3 3 0 Synaptobrevin zf-TRAF_2 PF15965.5 EGD86031.2 - 1.3e-07 32.0 3.0 2.3e-07 31.2 3.0 1.3 1 0 0 1 1 1 1 TRAF-like zinc-finger zf-TRAF PF02176.18 EGD86031.2 - 4e-06 27.4 6.9 4.5e-06 27.2 5.9 1.6 1 1 0 1 1 1 1 TRAF-type zinc finger TSC22 PF01166.18 EGD86031.2 - 0.0095 16.2 2.6 2.9 8.3 0.2 3.3 3 0 0 3 3 3 1 TSC-22/dip/bun family RasGAP_C PF03836.15 EGD86031.2 - 0.023 14.9 0.1 0.097 12.8 0.0 2.0 2 0 0 2 2 2 0 RasGAP C-terminus Sina PF03145.16 EGD86031.2 - 0.026 14.5 0.8 0.026 14.5 0.8 1.9 1 1 1 2 2 2 0 Seven in absentia protein family DivIC PF04977.15 EGD86031.2 - 0.033 13.9 0.1 1.6 8.6 0.0 2.5 3 0 0 3 3 3 0 Septum formation initiator DUF3972 PF13118.6 EGD86031.2 - 0.064 13.7 0.1 0.25 11.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) CENP-F_leu_zip PF10473.9 EGD86031.2 - 0.13 12.3 1.8 0.68 10.0 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2730 PF10805.8 EGD86031.2 - 0.21 11.7 1.5 2.7 8.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) PspA_IM30 PF04012.12 EGD86031.2 - 0.23 11.0 1.7 7.9 6.0 0.3 2.2 2 0 0 2 2 2 0 PspA/IM30 family TMF_DNA_bd PF12329.8 EGD86031.2 - 2.1 8.4 4.7 1.2 9.2 0.4 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Het-C PF07217.11 EGD86033.1 - 5.7e-279 926.4 0.0 7e-279 926.1 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C TctA PF01970.16 EGD86033.1 - 0.097 11.4 0.4 0.22 10.2 0.4 1.5 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Defensin_2 PF01097.18 EGD86034.1 - 2.5e-08 33.7 3.8 3.2e-08 33.4 3.8 1.1 1 0 0 1 1 1 1 Arthropod defensin Toxin_38 PF14866.6 EGD86034.1 - 8.2e-06 26.0 0.6 1.1e-05 25.6 0.6 1.2 1 0 0 1 1 1 1 Potassium channel toxin Gamma-thionin PF00304.20 EGD86034.1 - 0.03 14.6 2.4 0.041 14.2 2.4 1.1 1 0 0 1 1 1 0 Gamma-thionin family Metal_resist PF13801.6 EGD86035.2 - 0.0047 17.1 0.3 0.0047 17.1 0.3 1.7 2 0 0 2 2 2 1 Heavy-metal resistance DUF2336 PF10098.9 EGD86036.1 - 0.0049 16.4 6.8 0.0055 16.2 0.4 2.3 2 0 0 2 2 2 2 Uncharacterised protein conserved in bacteria (DUF2336) Med4 PF10018.9 EGD86036.1 - 0.083 12.6 6.8 0.19 11.4 6.8 1.6 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 UPF0242 PF06785.11 EGD86036.1 - 0.11 12.6 6.4 0.21 11.7 6.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ank_2 PF12796.7 EGD86037.2 - 5.7e-44 148.6 0.1 4.7e-11 43.1 0.0 8.7 8 1 0 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD86037.2 - 8.7e-35 118.7 1.7 0.00019 21.9 0.0 11.0 9 2 2 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD86037.2 - 3.9e-31 103.6 6.0 0.0016 18.8 0.1 12.2 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 EGD86037.2 - 1.4e-30 104.9 8.7 2e-05 24.8 0.0 11.1 11 0 0 11 11 11 4 Ankyrin repeats (many copies) Ank PF00023.30 EGD86037.2 - 7.3e-23 80.0 14.6 0.00094 19.5 0.1 10.3 11 2 0 11 11 11 6 Ankyrin repeat Tim44 PF04280.15 EGD86037.2 - 0.023 14.8 0.0 2.1 8.4 0.0 2.7 2 0 0 2 2 2 0 Tim44-like domain IBN_N PF03810.19 EGD86038.2 - 2e-11 43.6 0.9 3.4e-09 36.5 0.1 3.3 3 1 1 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGD86038.2 - 7.3e-05 22.9 0.5 0.00031 20.8 0.1 2.3 2 1 0 2 2 2 1 Exportin 1-like protein SAM_KSR1 PF13543.6 EGD86038.2 - 0.019 15.1 0.1 4.1 7.6 0.0 2.7 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Urb2 PF10441.9 EGD86038.2 - 0.052 13.5 0.2 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 Urb2/Npa2 family HORMA PF02301.18 EGD86041.1 - 4.6e-10 39.5 0.0 5.4e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 HORMA domain NAD_binding_2 PF03446.15 EGD86041.1 - 0.068 13.3 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IBR PF01485.21 EGD86042.1 - 2.5e-08 34.0 31.7 1.1e-07 32.0 8.1 3.7 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Pkinase PF00069.25 EGD86043.1 - 4.9e-17 62.2 0.0 7.5e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD86043.1 - 1.1e-08 34.7 0.0 2.9e-08 33.3 0.0 1.7 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD86043.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Acetyltransf_7 PF13508.7 EGD86045.1 - 0.00039 20.8 0.0 0.00069 20.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGD86045.1 - 0.0035 17.4 0.0 0.0079 16.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGD86045.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EGD86045.1 - 0.077 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.7 EGD86045.1 - 0.19 11.7 0.0 0.7 9.8 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Dcc1 PF09724.9 EGD86046.2 - 5.2e-30 104.9 6.3 1.3e-26 93.8 0.0 2.0 1 1 1 2 2 2 2 Sister chromatid cohesion protein Dcc1 SOG2 PF10428.9 EGD86046.2 - 1.4 8.0 19.8 1.9 7.6 19.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Anp1 PF03452.14 EGD86047.1 - 2.5e-111 371.3 0.0 2.5e-111 371.3 0.0 2.6 2 1 1 3 3 3 1 Anp1 PDEase_I PF00233.19 EGD86047.1 - 1.5 8.5 6.4 2.4 7.8 6.4 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Smg8_Smg9 PF10220.9 EGD86047.1 - 4.5 5.5 17.5 7.5 4.7 17.5 1.4 1 0 0 1 1 1 0 Smg8_Smg9 tRNA_bind PF01588.20 EGD86048.1 - 2.1e-20 72.6 0.2 1.1e-19 70.3 0.0 2.3 2 1 0 2 2 2 1 Putative tRNA binding domain GST_C_2 PF13410.6 EGD86048.1 - 0.029 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IHABP4_N PF16174.5 EGD86048.1 - 5.3 7.6 9.1 10 6.7 9.1 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Asp PF00026.23 EGD86049.2 - 2e-59 201.6 0.0 2.3e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGD86049.2 - 7e-08 32.9 0.3 0.0053 17.0 0.1 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGD86049.2 - 5.7e-06 26.9 0.5 0.025 15.2 0.1 2.6 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EGD86049.2 - 0.00011 22.6 0.2 0.057 14.0 0.1 2.8 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease PEMT PF04191.13 EGD86051.2 - 5.4e-61 203.6 8.4 6.9e-37 126.1 0.4 3.3 3 0 0 3 3 3 2 Phospholipid methyltransferase SKICH PF17751.1 EGD86051.2 - 0.032 14.8 0.1 1.2 9.8 0.0 2.4 2 0 0 2 2 2 0 SKICH domain HECW_N PF16562.5 EGD86051.2 - 0.045 13.6 0.1 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 RNase_PH PF01138.21 EGD86052.1 - 1.1e-26 93.9 0.0 2e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Lactamase_B PF00753.27 EGD86053.2 - 0.00013 22.1 0.1 0.0002 21.4 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGD86053.2 - 0.013 15.0 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain GST_N_3 PF13417.6 EGD86055.1 - 0.15 12.5 0.6 0.49 10.8 0.1 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain CDC27 PF09507.10 EGD86055.1 - 1.3 8.4 17.3 2.3 7.5 17.3 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MFS_1 PF07690.16 EGD86056.1 - 1.5e-44 152.4 35.2 1.5e-44 152.4 35.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD86056.1 - 2.8e-12 46.3 27.0 1.5e-11 43.8 27.0 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EGD86056.1 - 0.15 10.4 5.5 0.14 10.5 0.5 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector ProRS-C_1 PF09180.11 EGD86057.2 - 3e-23 81.8 3.0 6e-23 80.8 3.0 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EGD86057.2 - 8.4e-18 65.0 0.0 1.4e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGD86057.2 - 7.4e-13 48.5 0.0 1.9e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain Cpn60_TCP1 PF00118.24 EGD86058.1 - 2.9e-150 501.1 16.4 3.3e-150 501.0 16.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.32 EGD86059.2 - 6.4e-15 55.3 9.1 0.00021 22.0 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD86059.2 - 1.6e-07 31.5 0.0 0.0076 16.5 0.0 4.6 4 2 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3378 PF11858.8 EGD86059.2 - 0.12 12.5 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) WD40_like PF17005.5 EGD86059.2 - 0.2 11.0 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 WD40-like domain S1 PF00575.23 EGD86060.2 - 2.7e-70 232.7 37.4 1.8e-15 57.0 0.4 11.5 11 0 0 11 11 11 10 S1 RNA binding domain Suf PF05843.14 EGD86060.2 - 4.2e-06 27.0 0.0 0.013 15.5 0.0 3.3 1 1 2 3 3 3 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EGD86060.2 - 2.1e-05 25.0 0.0 0.0091 16.5 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 EGD86060.2 - 2.5e-05 24.1 0.2 1.4 8.9 0.0 5.3 5 0 0 5 5 5 1 RNase II-type exonuclease C-terminal S1 domain TPR_14 PF13428.6 EGD86060.2 - 0.0002 21.9 0.0 0.47 11.4 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat PCB_OB PF17092.5 EGD86060.2 - 0.00021 22.0 6.6 1.9 9.2 0.0 5.7 5 1 1 6 6 6 1 Penicillin-binding protein OB-like domain NRDE-2 PF08424.10 EGD86060.2 - 0.0097 15.1 0.0 0.045 12.9 0.0 1.9 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 EGD86060.2 - 0.015 16.0 0.0 22 5.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 EGD86060.2 - 0.04 14.2 0.0 19 5.8 0.0 3.5 2 1 1 3 3 3 0 PPR repeat Cue1_U7BR PF18499.1 EGD86060.2 - 0.076 13.1 0.5 0.24 11.5 0.0 2.1 2 0 0 2 2 1 0 Ubc7p-binding region of Cue1 DUF2187 PF09953.9 EGD86060.2 - 0.15 12.1 3.6 13 5.9 0.3 4.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2187) S1_2 PF13509.6 EGD86060.2 - 0.17 12.0 5.1 23 5.1 0.0 5.8 8 0 0 8 8 8 0 S1 domain CDC45 PF02724.14 EGD86060.2 - 2.9 6.1 9.2 5.6 5.1 9.2 1.3 1 0 0 1 1 1 0 CDC45-like protein UreD PF01774.17 EGD86063.1 - 6e-78 261.6 0.0 7.1e-78 261.4 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.11 EGD86064.2 - 1.6e-40 137.6 5.1 2.8e-40 136.8 1.5 2.9 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.6 EGD86064.2 - 0.0029 18.0 0.2 0.32 11.4 0.3 3.4 2 1 1 3 3 3 1 HEAT repeats FAM209 PF15206.6 EGD86064.2 - 0.014 15.2 0.0 0.046 13.5 0.0 1.9 1 0 0 1 1 1 0 FAM209 family DUF2408 PF10303.9 EGD86064.2 - 0.098 13.2 8.3 0.55 10.8 0.0 4.3 4 1 0 4 4 4 0 Protein of unknown function (DUF2408) HEAT PF02985.22 EGD86064.2 - 0.3 11.5 1.2 16 6.0 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat GFA PF04828.14 EGD86066.1 - 9.2e-14 51.6 1.7 1.3e-13 51.0 1.7 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.6 EGD86066.1 - 0.097 12.4 0.5 0.097 12.4 0.5 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Acatn PF13000.7 EGD86067.1 - 7.7e-156 519.8 16.3 9.7e-83 278.5 8.1 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.10 EGD86068.2 - 8.3e-66 222.0 0.0 1.1e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component NAM-associated PF14303.6 EGD86070.1 - 0.00066 20.4 0.2 0.021 15.5 0.0 2.9 1 1 1 2 2 2 1 No apical meristem-associated C-terminal domain Perilipin PF03036.16 EGD86070.1 - 0.71 8.8 13.1 0.49 9.3 4.6 2.1 1 1 1 2 2 2 0 Perilipin family CENP-H PF05837.12 EGD86070.1 - 2.1 8.8 10.3 0.19 12.2 0.7 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DFP PF04127.15 EGD86074.1 - 2.7e-12 46.9 0.0 6.9e-05 22.7 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Polysacc_deac_1 PF01522.21 EGD86075.1 - 7.5e-18 64.6 0.0 1.3e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGD86075.1 - 0.0081 15.4 0.1 0.021 14.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DEAD PF00270.29 EGD86076.1 - 3.3e-42 144.2 0.0 5.5e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD86076.1 - 2.6e-27 95.4 0.0 7.4e-26 90.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EGD86076.1 - 0.026 13.3 0.0 2.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 EGD86076.1 - 0.039 14.0 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Glyoxal_oxid_N PF07250.11 EGD86077.1 - 2.7e-37 128.2 0.0 1.2e-36 126.1 0.0 2.1 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EGD86077.1 - 3.3e-24 85.0 0.2 6.5e-24 84.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.19 EGD86077.1 - 4e-06 27.2 20.1 4e-06 27.2 20.1 2.5 2 0 0 2 2 2 1 Chitin recognition protein Kelch_6 PF13964.6 EGD86077.1 - 0.0016 18.6 0.4 23 5.5 0.0 5.5 6 0 0 6 6 6 1 Kelch motif Fumble PF03630.14 EGD86078.1 - 1.5e-144 481.2 0.7 1.9e-144 480.9 0.7 1.1 1 0 0 1 1 1 1 Fumble GPI2 PF06432.11 EGD86079.1 - 8.2e-129 429.0 6.0 1e-128 428.7 6.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Macoilin PF09726.9 EGD86080.1 - 0.0013 17.4 6.8 0.0015 17.2 6.8 1.0 1 0 0 1 1 1 1 Macoilin family NPR3 PF03666.13 EGD86080.1 - 0.14 10.9 8.5 0.19 10.5 8.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ORC6 PF05460.13 EGD86080.1 - 0.41 9.9 10.6 0.51 9.5 10.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Membralin PF09746.9 EGD86080.1 - 8.7 5.3 7.3 11 5.0 7.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Bunya_G2 PF03563.13 EGD86087.2 - 0.037 13.3 0.1 0.044 13.0 0.1 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 AA_permease_2 PF13520.6 EGD86091.1 - 1.9e-45 155.5 46.1 2.5e-45 155.1 46.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD86091.1 - 1.9e-27 96.0 39.6 2.6e-27 95.6 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease Orthoreo_P10 PF07204.11 EGD86091.1 - 1.2 9.2 0.0 1.2 9.2 0.0 2.9 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 DUF2254 PF10011.9 EGD86093.1 - 0.12 11.2 1.8 0.17 10.7 1.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) HemY_N PF07219.13 EGD86093.1 - 0.13 12.5 1.6 0.27 11.4 1.6 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Col_cuticle_N PF01484.17 EGD86093.1 - 0.84 9.8 6.2 2 8.6 6.2 1.7 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain LapA_dom PF06305.11 EGD86093.1 - 2 8.3 5.5 1.1 9.1 0.5 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain 5_nucleotid_C PF02872.18 EGD86095.1 - 3.9e-33 114.9 0.0 2.6e-31 109.0 0.0 2.4 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGD86095.1 - 0.00053 20.6 1.2 0.00087 19.8 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4869 PF16163.5 EGD86095.1 - 0.15 11.8 0.2 0.29 10.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4869) DUF5367 PF17329.2 EGD86096.1 - 0.02 15.0 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5367) DUF5385 PF17359.2 EGD86096.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) TMEM154 PF15102.6 EGD86096.1 - 0.029 14.3 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family DUF5305 PF17231.2 EGD86096.1 - 0.085 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Chordopox_A13L PF05961.11 EGD86096.1 - 0.098 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF2371 PF10177.9 EGD86096.1 - 0.15 12.3 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Kinetochor_Ybp2 PF08568.10 EGD86096.1 - 0.17 10.3 0.0 0.18 10.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Aldedh PF00171.22 EGD86097.1 - 5.8e-150 499.8 0.1 7.1e-150 499.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Gln-synt_C PF00120.24 EGD86102.2 - 1.2e-62 211.9 0.0 3.9e-62 210.3 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 EGD86102.2 - 5.9e-14 52.5 0.0 1e-13 51.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.16 EGD86103.1 - 2.3e-35 122.1 22.9 2.3e-35 122.1 22.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD86103.1 - 1.2e-13 50.8 11.5 1.2e-13 50.8 11.5 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EGD86103.1 - 0.0016 16.9 3.8 0.0026 16.2 3.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFA1_2 PF17317.2 EGD86103.1 - 0.18 11.6 0.8 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Mating hormone A-factor 1&2 UPF0016 PF01169.19 EGD86107.1 - 6.3e-39 132.2 26.4 1.7e-19 69.9 7.5 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2070 PF09843.9 EGD86107.1 - 0.0091 14.3 0.2 0.015 13.6 0.2 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Mntp PF02659.15 EGD86107.1 - 0.019 14.7 0.1 0.019 14.7 0.1 2.3 2 0 0 2 2 2 0 Putative manganese efflux pump Myb_DNA-binding PF00249.31 EGD86108.1 - 0.00013 22.0 0.3 0.00031 20.9 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain TRF PF08558.10 EGD86108.1 - 0.0014 18.3 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Annexin PF00191.20 EGD86109.1 - 5.8e-14 51.9 5.5 0.0009 19.3 0.1 4.6 4 1 0 4 4 4 4 Annexin Ribosomal_L21e PF01157.18 EGD86110.2 - 3.8e-47 158.3 3.8 3.8e-47 158.3 3.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e DUF5486 PF17588.2 EGD86110.2 - 0.27 11.1 2.7 1.3 9.0 0.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5486) S4 PF01479.25 EGD86111.1 - 3.7e-12 45.8 1.3 3.7e-12 45.8 1.3 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EGD86111.1 - 2e-06 28.6 0.2 4e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain BLOC1_2 PF10046.9 EGD86112.1 - 0.0016 18.7 6.2 0.0016 18.7 6.2 2.6 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3552 PF12072.8 EGD86112.1 - 0.0024 17.3 22.0 0.012 15.0 11.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3552) Bacillus_HBL PF05791.11 EGD86112.1 - 0.0062 16.4 0.6 0.0062 16.4 0.6 2.0 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF948 PF06103.11 EGD86112.1 - 0.009 16.3 3.0 0.016 15.4 0.3 2.2 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Kre28 PF17097.5 EGD86112.1 - 0.011 14.8 10.8 0.02 13.9 10.8 1.4 1 1 0 1 1 1 0 Spindle pole body component DUF1664 PF07889.12 EGD86112.1 - 0.037 14.1 1.2 0.037 14.1 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EGD86112.1 - 0.055 12.3 23.1 0.13 11.1 9.7 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF3103 PF11301.8 EGD86112.1 - 0.09 11.6 2.3 0.081 11.7 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3103) HIGH_NTase1 PF05636.11 EGD86112.1 - 0.12 11.5 4.3 0.15 11.2 4.3 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Exonuc_VII_L PF02601.15 EGD86112.1 - 0.16 11.5 10.8 0.057 13.0 8.1 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Med28 PF11594.8 EGD86112.1 - 0.18 11.9 2.9 0.21 11.7 1.4 1.9 1 1 1 2 2 2 0 Mediator complex subunit 28 MOSC_N PF03476.16 EGD86112.1 - 0.25 11.2 1.8 1.2 9.0 0.2 2.2 2 0 0 2 2 2 0 MOSC N-terminal beta barrel domain HIP1_clath_bdg PF16515.5 EGD86112.1 - 0.55 10.9 24.2 0.55 10.9 7.2 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 EGD86112.1 - 1.1 9.8 4.1 3.1 8.3 0.8 3.0 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EGD86112.1 - 1.4 9.0 6.3 0.52 10.4 1.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1216 PF06746.11 EGD86112.1 - 1.4 8.9 6.4 0.87 9.6 3.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) Fez1 PF06818.15 EGD86112.1 - 1.4 9.3 19.2 3.1 8.2 19.0 1.6 1 1 0 1 1 1 0 Fez1 Prefoldin PF02996.17 EGD86112.1 - 1.5 8.8 15.2 0.48 10.3 3.4 3.5 1 1 2 3 3 3 0 Prefoldin subunit GvpK PF05121.12 EGD86112.1 - 1.5 8.9 9.5 0.59 10.2 0.7 3.1 1 1 1 3 3 3 0 Gas vesicle protein K CC2-LZ PF16516.5 EGD86112.1 - 1.9 8.9 14.5 4.8 7.6 1.3 2.8 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator LMBR1 PF04791.16 EGD86112.1 - 2 7.2 5.1 2.4 7.0 5.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF16 PF01519.16 EGD86112.1 - 2 8.9 12.1 2.9 8.4 4.4 3.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 EGD86112.1 - 2.1 8.8 9.8 7.8 7.0 4.2 3.2 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 EGD86112.1 - 2.3 7.2 18.1 44 3.0 18.3 2.2 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Alb1 PF09135.11 EGD86112.1 - 2.5 9.0 9.4 11 6.9 9.4 2.1 1 1 0 1 1 1 0 Alb1 BST2 PF16716.5 EGD86112.1 - 3 8.5 17.7 1 10.0 7.2 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF1043 PF06295.12 EGD86112.1 - 3.7 7.6 13.0 2.7 8.0 6.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Fib_alpha PF08702.10 EGD86112.1 - 4.3 7.5 8.2 1.1 9.5 4.0 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.6 EGD86112.1 - 6.3 6.1 20.0 11 5.3 9.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 EGD86112.1 - 7.9 6.5 18.8 3.4 7.7 6.3 3.3 2 1 1 3 3 3 0 Prefoldin subunit Vault_2 PF17794.1 EGD86113.1 - 0.16 12.4 0.3 0.41 11.1 0.3 1.6 1 0 0 1 1 1 0 Major Vault Protein repeat domain Amidoligase_2 PF12224.8 EGD86114.2 - 0.061 13.0 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme Vps62 PF06101.11 EGD86115.1 - 1.5e-10 40.0 0.4 2.5e-08 32.7 0.2 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 Septin PF00735.18 EGD86117.2 - 2.1e-26 92.8 0.1 4.6e-09 36.0 0.1 3.2 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.18 EGD86117.2 - 0.037 13.4 0.0 0.098 12.0 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EGD86117.2 - 0.068 13.7 0.3 0.36 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGD86117.2 - 0.16 12.0 2.1 0.59 10.2 0.0 2.7 3 0 0 3 3 3 0 Dynamin family Mito_carr PF00153.27 EGD86118.2 - 3.9e-70 231.9 2.1 1e-24 86.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGD86118.2 - 0.15 11.2 0.1 0.72 8.9 0.0 2.2 2 1 0 2 2 2 0 Gammaproteobacterial serine protease DUF1908 PF08926.11 EGD86120.2 - 3.5 6.6 9.3 4 6.4 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) SecE PF00584.20 EGD86122.1 - 9.7e-14 51.0 0.0 1.2e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_1 PF00076.22 EGD86124.1 - 2.1e-06 27.4 0.0 3.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Menin PF05053.13 EGD86124.1 - 0.089 11.1 2.9 0.13 10.6 2.9 1.2 1 0 0 1 1 1 0 Menin Protamine_P2 PF00841.19 EGD86124.1 - 6.4 7.3 5.3 17 6.0 5.3 1.7 1 0 0 1 1 1 0 Sperm histone P2 WD40 PF00400.32 EGD86125.1 - 5.5e-19 68.2 17.3 0.0011 19.8 0.2 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EGD86125.1 - 2.2e-06 26.5 0.8 0.019 13.5 0.0 4.0 4 0 0 4 4 4 2 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 EGD86125.1 - 4.3e-05 23.7 0.0 0.34 11.2 0.0 4.2 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGD86125.1 - 0.00072 20.0 4.0 0.19 12.2 0.1 4.5 4 0 0 4 4 4 1 PQQ-like domain Nucleoporin_N PF08801.11 EGD86125.1 - 0.11 11.2 0.1 1.9 7.1 0.1 2.7 2 1 0 2 2 2 0 Nup133 N terminal like PD40 PF07676.12 EGD86125.1 - 0.29 11.1 0.1 0.29 11.1 0.1 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nop14 PF04147.12 EGD86125.1 - 3.1 5.9 12.3 4.2 5.5 12.3 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EGD86125.1 - 4.5 5.2 21.9 5.8 4.9 21.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi PX PF00787.24 EGD86126.1 - 3.1e-27 94.8 0.2 3.7e-27 94.6 0.2 1.1 1 0 0 1 1 1 1 PX domain Myb_DNA-bind_6 PF13921.6 EGD86127.1 - 3e-15 56.2 0.0 2.6e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGD86127.1 - 1.9e-12 47.2 0.1 3.9e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EGD86127.1 - 0.012 15.6 0.0 4.5 7.3 0.0 2.5 2 0 0 2 2 2 0 SLIDE Myb_DNA-bind_7 PF15963.5 EGD86127.1 - 0.066 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Myb DNA-binding like Nop16 PF09420.10 EGD86127.1 - 0.074 13.1 0.2 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 RasGEF PF00617.19 EGD86128.1 - 1.9e-05 24.9 0.0 5.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain Slu7 PF11708.8 EGD86130.1 - 1e-84 284.5 19.1 1e-84 284.5 19.1 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EGD86130.1 - 0.019 14.7 0.5 0.042 13.6 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EGD86130.1 - 0.3 11.2 2.8 0.57 10.4 2.8 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 EGD86130.1 - 1.2 8.9 4.5 2.6 7.8 4.5 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger ELP6 PF09807.9 EGD86132.1 - 1.1e-12 47.9 0.0 7.2e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Elongation complex protein 6 ATPase PF06745.13 EGD86132.1 - 0.23 10.8 0.0 0.56 9.5 0.0 1.5 2 0 0 2 2 2 0 KaiC RdRP PF05183.12 EGD86133.1 - 5.4e-195 649.4 0.0 7.1e-195 649.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 EGD86133.1 - 0.003 17.4 0.0 0.0091 15.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAP65_ASE1 PF03999.12 EGD86133.1 - 0.83 8.3 11.0 1.9 7.1 11.0 1.5 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) NUDE_C PF04880.13 EGD86133.1 - 7 7.1 18.8 7.9 6.9 0.7 2.6 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region AA_permease PF00324.21 EGD86134.1 - 1.4e-138 462.5 41.8 1.7e-138 462.2 41.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD86134.1 - 7e-37 127.3 45.5 8.5e-37 127.0 45.5 1.1 1 0 0 1 1 1 1 Amino acid permease DDE_Tnp_1_assoc PF13808.6 EGD86134.1 - 0.088 12.9 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 DDE_Tnp_1-associated Sulfate_transp PF00916.20 EGD86136.1 - 2.5e-117 391.9 17.7 3e-117 391.6 17.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGD86136.1 - 7.3e-08 32.1 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGD86136.1 - 7e-05 23.2 3.2 7e-05 23.2 3.2 2.9 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily FAD-oxidase_C PF02913.19 EGD86137.1 - 3.5e-58 197.2 0.0 4.5e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGD86137.1 - 5.1e-35 120.2 0.1 1.5e-34 118.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Ribosomal_S4e PF00900.20 EGD86138.1 - 8.7e-37 124.9 0.2 1.8e-36 123.9 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EGD86138.1 - 2e-24 85.0 0.1 3.4e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EGD86138.1 - 1.2e-18 66.9 7.0 2.4e-18 66.0 7.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EGD86138.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EGD86138.1 - 0.0047 16.8 1.1 0.0047 16.8 1.1 3.1 3 0 0 3 3 3 1 KOW motif Sipho_tail PF05709.11 EGD86138.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 1 1 0 1 1 1 0 Phage tail protein MATalpha_HMGbox PF04769.12 EGD86141.1 - 4.8e-34 117.4 0.0 6.8e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Glyco_hydro_72 PF03198.14 EGD86142.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase Exo_endo_phos PF03372.23 EGD86143.1 - 1.4e-14 54.2 0.0 2.1e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EGD86143.1 - 0.001 19.1 0.2 0.0026 17.8 0.2 1.7 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 EGD86143.1 - 0.0039 17.0 0.0 0.36 10.7 0.0 2.8 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase COX6A PF02046.15 EGD86144.2 - 2.3e-52 176.2 1.3 2.8e-52 175.9 1.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa I_LWEQ PF01608.17 EGD86145.2 - 7.7e-57 191.8 8.0 7.7e-57 191.8 8.0 6.4 3 2 1 6 6 6 2 I/LWEQ domain ANTH PF07651.16 EGD86145.2 - 1.7e-26 92.8 0.0 1.7e-26 92.8 0.0 3.0 2 1 0 2 2 2 1 ANTH domain MMM1 PF10296.9 EGD86146.1 - 1.9e-05 23.9 0.0 6.7e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 EGD86146.1 - 0.33 11.4 1.3 0.67 10.4 0.0 2.1 3 0 0 3 3 3 0 Pleckstrin homology domain Hemerythrin PF01814.23 EGD86147.1 - 4.2e-13 50.0 0.1 6.2e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MATalpha_HMGbox PF04769.12 EGD86147.1 - 0.0054 16.1 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box SKG6 PF08693.10 EGD86148.1 - 0.0083 15.5 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TrkA_TMD PF18613.1 EGD86148.1 - 8.9 5.8 8.4 0.39 10.2 2.6 1.7 2 0 0 2 2 2 0 Tyrosine kinase receptor A trans-membrane domain CIA30 PF08547.12 EGD86150.1 - 3.9e-39 134.2 0.0 2.8e-25 89.2 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SAICAR_synt PF01259.18 EGD86151.1 - 9.7e-97 323.5 0.0 1.1e-96 323.3 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase ANAPC5 PF12862.7 EGD86152.2 - 2.7e-30 104.3 1.3 6.9e-30 103.0 0.4 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 EGD86152.2 - 3e-05 24.2 4.2 0.31 11.4 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGD86152.2 - 8.5e-05 23.0 3.9 0.062 13.8 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGD86152.2 - 9.9e-05 21.9 1.4 0.00036 20.0 0.6 2.1 2 0 0 2 2 2 1 MalT-like TPR region Cohesin_load PF10345.9 EGD86152.2 - 0.0046 15.5 0.1 0.031 12.7 0.1 2.0 2 0 0 2 2 2 1 Cohesin loading factor TPR_21 PF09976.9 EGD86152.2 - 0.02 14.6 0.1 0.087 12.5 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_2 PF07719.17 EGD86152.2 - 0.033 14.3 0.2 25 5.3 0.0 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGD86152.2 - 0.098 13.3 2.5 17 6.4 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGD86152.2 - 0.11 12.4 0.3 20 5.2 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGD86152.2 - 0.12 12.5 0.1 9.1 6.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGD86152.2 - 2 9.2 11.1 4.4 8.1 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat SUI1 PF01253.22 EGD86153.2 - 4.3e-28 97.7 3.9 5.6e-28 97.3 3.9 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 EGD86153.2 - 0.084 13.1 0.4 0.13 12.5 0.4 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain MBA1 PF07961.11 EGD86156.1 - 3.4e-06 26.3 0.3 6.3e-06 25.4 0.3 1.4 1 1 0 1 1 1 1 MBA1-like protein SSF PF00474.17 EGD86157.2 - 4.9e-05 22.4 25.6 0.0002 20.3 25.6 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family 7tm_6 PF02949.20 EGD86157.2 - 0.69 8.9 4.1 1.7 7.7 4.1 1.6 1 0 0 1 1 1 0 7tm Odorant receptor Kinocilin PF15033.6 EGD86157.2 - 0.93 9.1 5.5 1.1 8.9 1.6 2.7 2 0 0 2 2 2 0 Kinocilin protein RexB PF15968.5 EGD86157.2 - 1 9.8 9.9 0.064 13.7 3.5 2.3 2 0 0 2 2 2 0 Membrane-anchored ion channel, Abi component RhoGAP PF00620.27 EGD86158.1 - 4.1e-48 163.1 0.0 9.5e-48 161.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EGD86158.1 - 5.9e-13 48.9 0.9 5.9e-13 48.9 0.9 2.9 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain OmpH PF03938.14 EGD86158.1 - 0.53 10.6 15.1 16 5.9 15.2 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ABM PF03992.16 EGD86159.1 - 2.1e-14 53.4 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Ras PF00071.22 EGD86160.1 - 2.1e-55 186.8 0.0 2.4e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD86160.1 - 1.6e-21 76.7 0.0 2.4e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD86160.1 - 5e-08 32.6 0.0 6.3e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 EGD86161.1 - 4.5e-12 45.6 0.9 7.8e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Totivirus_coat PF05518.11 EGD86161.1 - 7.9 4.4 11.6 13 3.7 11.6 1.2 1 0 0 1 1 1 0 Totivirus coat protein SURF1 PF02104.15 EGD86164.1 - 2.5e-47 161.4 0.0 3.4e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.20 EGD86165.2 - 1.4e-09 38.0 0.0 2.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain SIMPL PF04402.14 EGD86165.2 - 0.023 15.1 3.0 0.023 15.1 3.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF541) TFIIA PF03153.13 EGD86165.2 - 0.025 14.6 7.4 0.037 14.0 7.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2828 PF11443.8 EGD86165.2 - 0.66 8.0 4.1 0.91 7.5 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF737 PF05300.11 EGD86165.2 - 1.1 9.6 16.0 2.1 8.7 16.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Hamartin PF04388.12 EGD86165.2 - 1.2 7.7 11.5 1.8 7.1 11.5 1.2 1 0 0 1 1 1 0 Hamartin protein MSA-2c PF12238.8 EGD86165.2 - 3.7 7.5 9.2 7.1 6.6 9.2 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF3292 PF11696.8 EGD86165.2 - 4.4 5.6 10.2 8.1 4.7 10.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF2076 PF09849.9 EGD86166.1 - 7.1e-09 36.1 11.7 8.3e-09 35.9 11.7 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EGD86166.1 - 1.5e-05 25.0 2.5 2.3e-05 24.4 2.5 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EGD86166.1 - 0.073 13.1 0.3 0.11 12.5 0.3 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Bindin PF02084.15 EGD86166.1 - 0.19 12.0 3.4 0.24 11.6 3.4 1.2 1 0 0 1 1 1 0 Bindin Sas10_Utp3 PF04000.15 EGD86167.2 - 1.1e-14 54.8 0.6 1.1e-14 54.8 0.6 2.3 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Merozoite_SPAM PF07133.11 EGD86167.2 - 0.32 11.0 21.7 0.76 9.7 21.7 1.6 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) ApbA_C PF08546.11 EGD86168.2 - 1.5e-31 109.2 0.1 2.6e-31 108.4 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EGD86168.2 - 1.4e-24 86.4 0.0 2.7e-18 66.1 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Coq4 PF05019.13 EGD86169.1 - 1.1e-96 322.4 0.0 1.3e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.20 EGD86170.1 - 5.2e-39 133.0 10.5 6.1e-39 132.7 10.5 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Sec2p PF06428.11 EGD86171.2 - 4.2e-14 52.3 7.5 8.1e-14 51.4 7.5 1.5 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p CENP-Q PF13094.6 EGD86171.2 - 0.012 15.9 0.5 0.039 14.2 0.0 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PRP21_like_P PF12230.8 EGD86172.1 - 2.1e-55 187.9 8.4 3.7e-30 105.4 2.3 2.2 2 0 0 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EGD86172.1 - 1.6e-36 124.1 3.0 9.3e-18 64.0 0.1 2.4 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 EGD86172.1 - 0.024 14.2 0.6 0.058 13.0 0.6 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger UPF0547 PF10571.9 EGD86172.1 - 0.25 11.5 1.5 0.85 9.8 1.5 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Toprim_Crpt PF13342.6 EGD86172.1 - 0.69 9.9 1.9 7.5 6.6 0.5 2.3 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase PMT_4TMC PF16192.5 EGD86173.2 - 6.6e-65 218.4 17.3 8.6e-65 218.1 17.3 1.1 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGD86173.2 - 3.3e-47 160.7 0.0 6e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 MIR domain Arteri_Gl PF00951.18 EGD86173.2 - 0.0015 18.4 1.3 0.0024 17.7 1.3 1.2 1 0 0 1 1 1 1 Arterivirus GL envelope glycoprotein DHHC PF01529.20 EGD86175.1 - 3.8e-34 117.7 7.6 3.8e-34 117.7 7.6 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.17 EGD86175.1 - 0.21 11.3 4.5 0.32 10.7 0.2 2.1 2 0 0 2 2 2 0 Yip1 domain SET PF00856.28 EGD86176.1 - 2.4e-14 54.1 2.4 3.7e-13 50.2 0.2 3.4 2 1 0 2 2 2 1 SET domain AWS PF17907.1 EGD86176.1 - 2.6e-07 30.5 10.0 2.6e-07 30.5 10.0 2.2 3 0 0 3 3 3 1 AWS domain Complex1_LYR PF05347.15 EGD86178.2 - 2.5e-18 65.8 5.9 2.7e-18 65.8 4.6 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGD86178.2 - 3.3e-06 27.7 3.1 3.9e-06 27.5 3.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Catalase-rel PF06628.12 EGD86178.2 - 0.63 10.3 4.6 6.6 7.0 2.8 2.7 1 1 1 2 2 2 0 Catalase-related immune-responsive PMC2NT PF08066.12 EGD86179.1 - 0.052 14.2 0.1 0.18 12.5 0.0 1.9 2 0 0 2 2 2 0 PMC2NT (NUC016) domain CDC45 PF02724.14 EGD86179.1 - 2.4 6.3 4.5 3.5 5.8 4.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 EGD86180.2 - 0.81 8.3 3.0 0.94 8.1 3.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mucin PF01456.17 EGD86181.2 - 0.002 18.1 14.0 0.0044 17.0 14.0 1.7 1 0 0 1 1 1 1 Mucin-like glycoprotein AJAP1_PANP_C PF15298.6 EGD86181.2 - 0.33 11.1 12.5 9.1 6.4 0.0 2.4 2 0 0 2 2 2 0 AJAP1/PANP C-terminus hEGF PF12661.7 EGD86181.2 - 0.37 11.5 7.6 0.84 10.4 7.6 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_CA PF07645.15 EGD86181.2 - 0.81 9.9 5.6 1.8 8.8 5.6 1.5 1 0 0 1 1 1 0 Calcium-binding EGF domain MAP65_ASE1 PF03999.12 EGD86181.2 - 1.1 7.8 4.1 1.8 7.2 4.1 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) EGF PF00008.27 EGD86181.2 - 1.4 9.3 8.3 3.1 8.2 8.3 1.6 1 0 0 1 1 1 0 EGF-like domain Filament_head PF04732.14 EGD86181.2 - 8 7.4 19.3 0.88 10.5 10.9 3.1 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region ATP-sulfurylase PF01747.17 EGD86183.1 - 2.5e-87 291.8 0.0 3.6e-87 291.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EGD86183.1 - 1.2e-57 194.2 0.0 1.9e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EGD86183.1 - 3.4e-50 169.8 0.0 5.6e-50 169.1 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain PAPS_reduct PF01507.19 EGD86187.1 - 4.6e-43 147.2 0.0 6.5e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.7 EGD86188.1 - 6.8e-23 82.0 0.1 1.1e-22 81.3 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGD86188.1 - 3.6e-19 69.9 0.5 4.8e-19 69.5 0.5 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGD86188.1 - 3.8e-07 30.1 0.1 4.4e-06 26.6 0.0 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGD86188.1 - 0.00043 20.4 0.0 0.0074 16.4 0.0 2.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EGD86188.1 - 0.0028 17.1 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 Putative Phosphatase DUF705 PF05152.12 EGD86188.1 - 0.051 13.0 0.1 0.075 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) PNK3P PF08645.11 EGD86188.1 - 0.087 12.5 0.0 5 6.8 0.0 2.4 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase LIAS_N PF16881.5 EGD86189.1 - 3.1e-26 91.9 0.0 7.6e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EGD86189.1 - 8.6e-14 52.2 0.0 1.5e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily WD40 PF00400.32 EGD86190.2 - 2e-10 41.0 4.7 4.6e-05 24.1 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Nefa_Nip30_N PF10187.9 EGD86190.2 - 0.0059 16.9 1.4 0.01 16.1 1.4 1.3 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 ANAPC4_WD40 PF12894.7 EGD86190.2 - 0.0066 16.7 0.0 7.8 6.9 0.0 4.0 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PPP4R2 PF09184.11 EGD86190.2 - 0.014 15.0 5.9 0.021 14.4 5.9 1.3 1 0 0 1 1 1 0 PPP4R2 Gryzun-like PF12742.7 EGD86190.2 - 0.097 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking CorA PF01544.18 EGD86190.2 - 0.25 10.6 2.6 0.41 9.9 2.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DeoC PF01791.9 EGD86192.1 - 3.6e-16 59.5 2.1 5.1e-16 59.0 2.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 EGD86192.1 - 0.00018 20.8 2.3 0.00029 20.1 2.1 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 EGD86192.1 - 0.017 14.6 0.5 0.035 13.6 0.5 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein IMPDH PF00478.25 EGD86192.1 - 0.023 13.7 1.7 0.033 13.2 1.7 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGD86192.1 - 0.032 13.3 0.4 0.058 12.4 0.4 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase ComA PF02679.15 EGD86192.1 - 0.084 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) SelK_SelG PF10961.8 EGD86193.1 - 1.1e-08 35.5 14.4 9.8e-08 32.5 4.8 2.1 1 1 1 2 2 2 2 Selenoprotein SelK_SelG TP_methylase PF00590.20 EGD86194.1 - 7.1e-46 156.8 0.0 1.2e-45 156.1 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EGD86194.1 - 3.6e-14 53.1 0.0 6.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EGD86194.1 - 1.4e-08 34.3 0.0 4.5e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EGD86194.1 - 1e-05 24.9 0.2 1e-05 24.9 0.2 2.6 3 0 0 3 3 3 1 Sirohaem biosynthesis protein central PrcB_C PF14343.6 EGD86195.1 - 0.063 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 PrcB C-terminal PCI PF01399.27 EGD86196.1 - 1.5e-22 80.0 0.0 5.3e-22 78.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 EGD86196.1 - 2.1e-16 59.7 1.9 5.3e-16 58.4 1.9 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain FSH1 PF03959.13 EGD86197.2 - 1.5e-26 93.4 0.0 1.8e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EGD86197.2 - 0.1 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DLH PF01738.18 EGD86197.2 - 0.14 11.7 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family APG6_N PF17675.1 EGD86202.1 - 0.85 10.1 4.8 0.24 11.9 1.6 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF5313 PF17240.2 EGD86203.2 - 5.5 7.4 5.7 20 5.7 1.8 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5313) NIPSNAP PF07978.13 EGD86204.1 - 2.3e-41 140.1 0.4 1.3e-29 102.5 0.1 2.3 2 0 0 2 2 2 2 NIPSNAP MSA-2c PF12238.8 EGD86204.1 - 1.2 9.1 6.2 2 8.3 6.2 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Putative_PNPOx PF01243.20 EGD86205.1 - 3.4e-12 46.4 0.0 7.3e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EGD86205.1 - 0.065 13.2 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Peptidase_C65 PF10275.9 EGD86206.2 - 2.6e-61 207.2 0.0 3.4e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain PCI PF01399.27 EGD86208.2 - 7e-16 58.7 0.4 1.7e-15 57.4 0.1 1.8 2 0 0 2 2 2 1 PCI domain DUF4423 PF14394.6 EGD86208.2 - 0.0071 16.1 0.0 8.2 6.1 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4423) CWC25 PF12542.8 EGD86209.1 - 4.3e-25 88.6 0.3 4.3e-25 88.6 0.3 4.1 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EGD86209.1 - 8.2e-14 51.5 10.3 8.2e-14 51.5 10.3 5.1 5 2 2 7 7 7 1 N-terminal domain of CBF1 interacting co-repressor CIR Ras PF00071.22 EGD86210.1 - 7.1e-53 178.5 0.0 8.3e-53 178.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD86210.1 - 8.6e-22 77.6 0.0 1.3e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD86210.1 - 8.7e-11 41.6 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGD86210.1 - 6.8e-05 22.3 0.0 8.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGD86210.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGD86210.1 - 0.0024 17.1 0.0 0.0041 16.3 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EGD86210.1 - 0.0076 16.3 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGD86210.1 - 0.021 14.7 0.0 6.3 6.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EGD86210.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EGD86210.1 - 0.14 12.7 0.0 0.27 11.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter BPL_LplA_LipB PF03099.19 EGD86211.1 - 8.5e-06 25.7 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family UPF0113_N PF17833.1 EGD86212.1 - 0.11 13.1 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 UPF0113 Pre-PUA domain Ank_2 PF12796.7 EGD86214.2 - 4.1e-20 72.2 1.8 7.3e-07 29.7 0.2 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD86214.2 - 2.3e-16 59.9 1.2 7.3e-07 29.6 0.4 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGD86214.2 - 9e-16 57.5 4.5 0.0037 17.6 0.1 4.7 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EGD86214.2 - 2.8e-13 49.8 4.3 0.0046 17.3 0.4 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD86214.2 - 2.4e-12 45.9 0.4 0.019 15.5 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat polyprenyl_synt PF00348.17 EGD86215.2 - 2.7e-67 226.5 0.0 3.4e-66 222.9 0.0 2.0 1 1 0 1 1 1 1 Polyprenyl synthetase DUF3659 PF12396.8 EGD86215.2 - 0.063 13.2 0.0 0.74 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Rpn3_C PF08375.11 EGD86216.1 - 9.9e-26 90.0 0.6 9.9e-26 90.0 0.6 2.2 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EGD86216.1 - 2.5e-21 76.2 0.8 8.4e-21 74.5 0.0 2.3 3 0 0 3 3 3 1 PCI domain DASH_Spc34 PF08657.10 EGD86218.2 - 6.6e-44 150.6 7.1 1.4e-21 77.5 3.7 2.1 1 1 1 2 2 2 2 DASH complex subunit Spc34 DUF848 PF05852.11 EGD86218.2 - 0.0027 17.9 4.9 0.0057 16.8 4.9 1.5 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) DASH_Spc19 PF08287.11 EGD86218.2 - 0.038 13.9 3.3 0.086 12.7 3.3 1.5 1 0 0 1 1 1 0 Spc19 Tropomyosin_1 PF12718.7 EGD86218.2 - 0.13 12.4 10.6 0.26 11.4 10.6 1.4 1 0 0 1 1 1 0 Tropomyosin like Prefoldin_2 PF01920.20 EGD86218.2 - 0.34 10.9 7.7 2.7 8.0 0.7 2.8 3 0 0 3 3 3 0 Prefoldin subunit DHR10 PF18595.1 EGD86218.2 - 0.77 9.8 10.7 4.1 7.5 1.6 2.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Fez1 PF06818.15 EGD86218.2 - 1.6 9.1 7.0 0.38 11.2 3.5 1.6 2 0 0 2 2 2 0 Fez1 DUF1664 PF07889.12 EGD86218.2 - 2.6 8.1 6.2 20 5.3 0.2 2.9 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 EGD86218.2 - 3.7 7.7 12.9 63 3.7 8.9 2.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 EGD86218.2 - 4 7.5 9.7 5.6 7.0 0.4 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding F-box PF00646.33 EGD86219.2 - 0.00044 20.1 0.0 0.00085 19.1 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGD86219.2 - 0.041 13.8 0.5 0.12 12.2 0.5 1.8 1 0 0 1 1 1 0 F-box-like TFIID_20kDa PF03847.13 EGD86220.1 - 1.3e-23 83.2 0.0 2.3e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CorA PF01544.18 EGD86221.2 - 2.9e-15 56.4 1.4 5e-15 55.6 1.4 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein STE PF02200.16 EGD86221.2 - 0.078 13.4 0.0 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 STE like transcription factor DUF1203 PF06718.11 EGD86222.1 - 5.7e-37 126.5 0.0 7.1e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1203) DUF1889 PF08986.10 EGD86222.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) eIF2A PF08662.11 EGD86225.1 - 2.8e-84 281.8 0.1 9.1e-83 276.9 0.1 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EGD86225.1 - 0.015 16.1 0.8 2.3 9.2 0.1 3.9 3 1 0 4 4 4 0 WD domain, G-beta repeat PRP38_assoc PF12871.7 EGD86225.1 - 0.58 10.8 16.7 1.2 9.7 16.7 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term NAD_binding_6 PF08030.12 EGD86226.2 - 8.1e-34 117.0 0.0 1.3e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGD86226.2 - 8.9e-23 80.5 0.2 3.7e-22 78.5 0.0 2.2 3 0 0 3 3 3 1 FAD-binding domain Ferric_reduct PF01794.19 EGD86226.2 - 2.1e-17 63.4 16.7 2.5e-17 63.2 8.5 2.4 1 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 EGD86226.2 - 0.019 15.3 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGD86226.2 - 0.079 13.6 0.0 0.27 11.9 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Acetyltransf_13 PF13880.6 EGD86228.1 - 3.4e-26 91.0 0.0 7.8e-26 89.8 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EGD86228.1 - 2.6e-11 43.2 0.2 4.8e-11 42.3 0.2 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO FSA_C PF10479.9 EGD86228.1 - 0.03 12.5 7.6 0.051 11.7 7.6 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 EGD86228.1 - 0.035 12.1 1.7 0.045 11.8 1.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CxC5 PF18718.1 EGD86228.1 - 0.076 13.1 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases SSP160 PF06933.11 EGD86228.1 - 1.5 6.9 15.1 2.8 6.0 15.1 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Acyl-CoA_dh_1 PF00441.24 EGD86230.2 - 1.1e-23 84.1 0.1 1.5e-23 83.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGD86230.2 - 3.5e-20 72.7 0.0 8.2e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGD86230.2 - 7.5e-16 58.1 0.0 1.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGD86230.2 - 2.2e-07 31.2 0.5 3.4e-07 30.6 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.26 EGD86231.1 - 5.2e-52 175.2 0.0 5.8e-52 175.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGD86231.1 - 0.00097 18.8 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGD86231.1 - 0.033 14.5 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EGD86231.1 - 0.068 13.0 0.2 0.13 12.1 0.2 1.4 1 1 0 1 1 1 0 UEV domain EMG1 PF03587.14 EGD86234.1 - 4.2e-79 264.7 0.0 5.1e-79 264.5 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Linker_histone PF00538.19 EGD86236.1 - 3e-29 101.2 0.2 3e-29 101.2 0.2 2.6 2 1 1 3 3 3 1 linker histone H1 and H5 family SRP-alpha_N PF04086.13 EGD86236.1 - 0.042 13.8 31.2 0.057 13.3 31.2 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Toxin_trans PF07952.12 EGD86236.1 - 0.072 12.2 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain SAPS PF04499.15 EGD86236.1 - 0.34 9.6 7.5 0.5 9.1 7.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MAM33 PF02330.16 EGD86236.1 - 9.8 6.0 8.9 1.6e+02 2.1 8.9 2.2 1 1 0 1 1 1 0 Mitochondrial glycoprotein F-box_4 PF15966.5 EGD86237.1 - 0.0051 16.7 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 EGD86237.1 - 0.0054 16.6 0.1 0.015 15.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD86237.1 - 0.095 12.6 0.3 0.56 10.2 0.2 2.4 2 0 0 2 2 2 0 F-box domain Pkinase PF00069.25 EGD86238.1 - 1.8e-22 80.0 0.0 2.4e-21 76.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD86238.1 - 1.4e-08 34.3 0.6 0.0076 15.6 0.0 3.5 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EGD86238.1 - 0.004 17.1 0.3 0.088 12.7 0.1 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGD86239.1 - 6.5e-17 61.8 0.0 5.2e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD86239.1 - 3e-05 23.5 0.1 6.3e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD86239.1 - 0.0018 17.6 0.1 0.024 14.0 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EGD86239.1 - 0.0022 16.8 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGD86239.1 - 0.021 14.8 0.1 0.062 13.2 0.1 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGD86239.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP5K PF01504.18 EGD86240.1 - 1e-100 336.5 0.0 1e-100 336.5 0.0 2.5 3 1 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase Fungal_trans_2 PF11951.8 EGD86244.2 - 4.2e-29 101.5 0.3 7.1e-29 100.8 0.3 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EGD86245.2 - 4.3e-22 78.5 27.1 4.3e-22 78.5 27.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily P5-ATPase PF12409.8 EGD86245.2 - 0.041 14.0 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 P5-type ATPase cation transporter RPAP1_C PF08620.10 EGD86247.1 - 9.2e-24 83.3 0.0 1.6e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EGD86247.1 - 9.2e-15 54.1 8.2 9.2e-15 54.1 8.2 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal Borrelia_P83 PF05262.11 EGD86247.1 - 7.5 4.9 9.2 11 4.4 9.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ABC2_membrane PF01061.24 EGD86248.2 - 3.4e-74 248.8 62.2 1.9e-39 135.3 22.8 3.4 4 1 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EGD86248.2 - 7.2e-40 136.7 0.1 1.8e-18 67.4 0.0 3.3 4 0 0 4 4 4 2 ABC transporter PDR_CDR PF06422.12 EGD86248.2 - 8.1e-31 105.8 10.8 1.4e-25 89.0 0.0 3.7 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EGD86248.2 - 1.9e-15 57.2 0.0 4.4e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 EGD86248.2 - 1.6e-07 31.6 0.2 0.0028 17.8 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGD86248.2 - 2.2e-06 27.4 0.0 5e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EGD86248.2 - 2.7e-06 26.7 12.5 2.7e-06 26.7 12.5 3.6 2 2 1 3 3 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 EGD86248.2 - 3.5e-06 26.7 0.5 0.0031 17.2 0.1 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGD86248.2 - 1.5e-05 24.9 0.1 0.22 11.3 0.1 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGD86248.2 - 1.9e-05 24.2 0.0 0.095 12.1 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGD86248.2 - 4.2e-05 23.5 0.1 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGD86248.2 - 4.8e-05 23.8 0.2 0.002 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EGD86248.2 - 5.6e-05 23.7 0.0 0.00082 19.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGD86248.2 - 0.0013 19.3 0.0 0.073 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGD86248.2 - 0.0017 18.4 0.1 2.8 8.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 EGD86248.2 - 0.0044 16.6 0.6 0.036 13.7 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_2 PF12679.7 EGD86248.2 - 0.0044 16.4 9.5 0.0044 16.4 9.5 2.5 2 0 0 2 2 2 1 ABC-2 family transporter protein NACHT PF05729.12 EGD86248.2 - 0.0088 16.0 1.4 1.3 9.0 0.3 2.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EGD86248.2 - 0.014 15.7 0.9 0.43 10.8 0.2 2.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EGD86248.2 - 0.025 15.0 0.1 4.5 7.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGD86248.2 - 0.046 13.5 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGD86248.2 - 0.051 14.0 0.3 0.54 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGD86248.2 - 0.055 13.9 0.0 26 5.3 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Pax2_C PF12403.8 EGD86248.2 - 0.1 12.7 0.6 0.57 10.3 0.3 2.3 1 1 1 2 2 2 0 Paired-box protein 2 C terminal AAA_28 PF13521.6 EGD86248.2 - 0.15 12.3 0.2 0.39 10.9 0.2 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGD86248.2 - 0.24 10.6 0.0 25 3.9 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain IDO PF01231.18 EGD86250.2 - 7.2e-09 34.9 1.6 5.4e-08 32.0 1.6 2.2 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase FAD_binding_3 PF01494.19 EGD86251.1 - 3.3e-11 43.0 0.1 1.1e-07 31.4 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGD86251.1 - 9.2e-06 25.5 0.6 0.00015 21.5 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGD86251.1 - 7.8e-05 22.8 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EGD86251.1 - 0.00025 20.0 0.1 0.039 12.8 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EGD86251.1 - 0.00035 19.9 0.1 0.16 11.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EGD86251.1 - 0.0075 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.6 EGD86251.1 - 0.0086 16.1 0.0 0.05 13.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Methyltransf_23 PF13489.6 EGD86253.1 - 5.4e-17 62.1 0.0 1.5e-16 60.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD86253.1 - 1.5e-08 35.2 0.0 6.3e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD86253.1 - 2.3e-07 30.7 0.0 0.0077 16.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGD86253.1 - 4.8e-07 30.4 0.0 1.1e-05 26.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD86253.1 - 3.9e-06 27.4 0.0 1.1e-05 26.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGD86253.1 - 0.051 13.0 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 EGD86253.1 - 0.064 12.8 0.0 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 EGD86253.1 - 0.09 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EGD86253.1 - 0.11 12.2 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Lysine methyltransferase IFRD PF05004.13 EGD86254.1 - 4.8e-82 275.5 12.3 6.1e-82 275.2 12.3 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) RRN3 PF05327.11 EGD86254.1 - 0.36 9.3 13.4 0.62 8.5 4.0 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 ORC6 PF05460.13 EGD86254.1 - 3.1 7.0 10.3 0.19 11.0 3.8 2.0 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Pkinase PF00069.25 EGD86255.1 - 3.3e-63 213.5 0.0 4e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD86255.1 - 5.4e-35 120.9 0.0 7.5e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD86255.1 - 7.8e-05 21.6 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGD86255.1 - 0.051 12.9 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EGD86255.1 - 0.073 12.0 0.0 0.16 10.9 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGD86255.1 - 0.098 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EGD86255.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family SH2_2 PF14633.6 EGD86256.1 - 5.1e-56 189.5 1.3 5.1e-56 189.5 1.3 3.1 4 0 0 4 4 4 1 SH2 domain HTH_44 PF14641.6 EGD86256.1 - 2.3e-38 131.2 6.3 9.6e-37 125.9 0.5 2.8 2 0 0 2 2 2 2 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 EGD86256.1 - 1.1e-30 106.1 0.0 2.3e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EGD86256.1 - 1.7e-29 102.6 0.0 5.3e-29 100.9 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 EGD86256.1 - 1.4e-18 67.3 22.3 1.4e-18 67.3 22.3 5.9 7 0 0 7 7 7 1 Acidic N-terminal SPT6 HHH_3 PF12836.7 EGD86256.1 - 1.1e-05 25.6 0.0 3.4e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 EGD86256.1 - 0.00015 22.6 3.1 0.00015 22.6 3.1 4.4 3 2 1 4 4 4 1 HHH domain SH2 PF00017.24 EGD86256.1 - 0.00025 21.1 0.0 0.0011 19.1 0.0 2.2 2 0 0 2 2 2 1 SH2 domain DUF445 PF04286.12 EGD86256.1 - 0.0093 15.8 3.6 16 5.1 0.1 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF445) Tex_YqgF PF16921.5 EGD86256.1 - 0.098 13.1 0.0 0.65 10.5 0.0 2.3 2 0 0 2 2 2 0 Tex protein YqgF-like domain Acetyltransf_3 PF13302.7 EGD86257.1 - 1.1e-22 81.2 0.0 1.5e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGD86257.1 - 4.1e-06 27.0 0.0 2.1e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGD86257.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein zf-CCCH PF00642.24 EGD86258.1 - 1.3e-11 44.0 9.3 1.4e-06 28.1 1.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGD86258.1 - 1.5e-09 37.6 16.4 7.5e-06 25.8 1.8 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EGD86258.1 - 2.2e-09 36.9 9.6 4.3e-06 26.4 2.2 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 EGD86258.1 - 3.1e-06 27.8 4.1 0.00069 20.3 0.3 3.6 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 EGD86258.1 - 0.00013 22.1 0.1 0.00026 21.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGD86258.1 - 0.01 16.3 14.3 0.24 12.0 3.3 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger TBPIP PF07106.13 EGD86259.2 - 2.5e-08 33.7 0.4 6e-08 32.5 0.4 1.6 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain DUF4140 PF13600.6 EGD86259.2 - 0.024 15.1 4.4 0.051 14.0 1.2 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prominin PF05478.11 EGD86259.2 - 0.026 12.5 3.9 0.034 12.1 3.9 1.2 1 0 0 1 1 1 0 Prominin Penicillinase_R PF03965.16 EGD86259.2 - 0.044 14.1 2.7 0.051 13.9 1.8 1.6 1 1 0 1 1 1 0 Penicillinase repressor PspA_IM30 PF04012.12 EGD86259.2 - 0.067 12.8 10.7 0.12 11.9 10.7 1.5 1 1 0 1 1 1 0 PspA/IM30 family Seryl_tRNA_N PF02403.22 EGD86259.2 - 0.35 11.1 6.5 0.098 12.9 3.2 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 EGD86259.2 - 0.73 10.5 4.0 11 6.7 4.0 2.4 1 1 0 1 1 1 0 Initiation control protein YabA HalX PF08663.10 EGD86259.2 - 0.94 9.8 6.5 5.3 7.4 0.9 2.4 1 1 1 2 2 2 0 HalX domain Sel1 PF08238.12 EGD86260.1 - 1.5e-16 60.4 19.0 2.8e-07 31.0 0.1 6.7 7 1 0 7 7 7 4 Sel1 repeat TPR_1 PF00515.28 EGD86260.1 - 0.33 10.8 2.8 0.72 9.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C_2 PF13307.6 EGD86261.1 - 1.1e-54 185.1 0.0 1.4e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain PhoD PF09423.10 EGD86261.1 - 0.1 11.6 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 PhoD-like phosphatase Ribosomal_L27A PF00828.19 EGD86262.1 - 2.3e-22 80.0 0.0 3.2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Hydrolase_4 PF12146.8 EGD86263.1 - 0.015 14.6 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGD86263.1 - 0.063 12.7 0.0 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PLDc PF00614.22 EGD86264.1 - 2.4e-17 62.3 0.4 4.6e-08 32.9 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGD86264.1 - 3.9e-13 49.5 0.0 6.3e-07 29.3 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 EGD86264.1 - 7.3e-10 38.8 0.2 2.2e-09 37.3 0.2 1.9 1 0 0 1 1 1 1 PX domain AA_permease PF00324.21 EGD86265.2 - 2.3e-58 197.9 22.5 1.2e-57 195.7 22.5 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD86265.2 - 3.4e-25 88.8 17.6 5e-25 88.2 17.6 1.3 1 0 0 1 1 1 1 Amino acid permease MtN3_slv PF03083.16 EGD86265.2 - 1.2 9.2 6.2 2.2 8.4 0.2 3.8 4 0 0 4 4 4 0 Sugar efflux transporter for intercellular exchange Herpes_BBRF1 PF04793.12 EGD86267.1 - 0.14 11.2 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 BRRF1-like protein Methyltransf_31 PF13847.6 EGD86268.2 - 3.3e-27 95.1 0.1 6.4e-27 94.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD86268.2 - 3e-19 69.5 0.1 1.1e-18 67.8 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD86268.2 - 1.6e-16 60.7 0.4 1.2e-15 57.9 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD86268.2 - 1e-15 57.7 0.1 3e-15 56.2 0.1 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGD86268.2 - 2e-09 37.5 0.0 4.2e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EGD86268.2 - 4e-09 36.5 0.0 1.1e-08 35.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD86268.2 - 5.1e-08 33.6 0.0 1e-07 32.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGD86268.2 - 4.7e-07 29.5 0.2 1.1e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGD86268.2 - 1.6e-05 24.5 0.1 3e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EGD86268.2 - 5.4e-05 23.2 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGD86268.2 - 7.8e-05 22.1 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 EGD86268.2 - 0.0009 18.8 0.9 0.0025 17.4 0.5 2.0 2 1 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_3 PF01596.17 EGD86268.2 - 0.0013 17.9 0.1 0.0033 16.6 0.1 1.6 1 1 0 1 1 1 1 O-methyltransferase UPF0020 PF01170.18 EGD86268.2 - 0.0037 17.0 0.2 0.0072 16.0 0.2 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 ADH_zinc_N PF00107.26 EGD86268.2 - 0.005 16.8 0.1 0.048 13.7 0.1 2.5 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.7 EGD86268.2 - 0.015 15.2 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 EGD86268.2 - 0.033 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 EGD86268.2 - 0.046 13.2 0.2 0.13 11.8 0.2 1.8 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.19 EGD86268.2 - 0.056 13.6 0.1 0.13 12.4 0.1 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase CheR PF01739.18 EGD86268.2 - 0.1 12.1 0.3 18 4.8 0.1 2.9 2 1 1 3 3 3 0 CheR methyltransferase, SAM binding domain FliC_SP PF12613.8 EGD86268.2 - 8 7.1 6.7 1.1 9.8 0.8 2.6 3 0 0 3 3 3 0 Flagellin structural protein bZIP_1 PF00170.21 EGD86269.1 - 0.044 13.9 5.7 0.073 13.2 5.5 1.5 1 1 0 1 1 1 0 bZIP transcription factor Snf7 PF03357.21 EGD86269.1 - 0.09 12.4 0.4 0.13 11.8 0.4 1.2 1 0 0 1 1 1 0 Snf7 YonK PF09642.10 EGD86269.1 - 0.22 11.7 0.0 0.39 10.9 0.0 1.3 1 0 0 1 1 1 0 YonK protein Hamartin PF04388.12 EGD86269.1 - 0.25 10.0 6.4 0.31 9.7 6.4 1.2 1 0 0 1 1 1 0 Hamartin protein Ras PF00071.22 EGD86271.1 - 4.4e-37 127.2 0.0 6.7e-24 84.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGD86271.1 - 1.6e-10 41.2 0.0 3.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD86271.1 - 0.017 14.6 0.0 0.061 12.8 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGD86271.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGD86271.1 - 0.069 12.7 0.0 1.2 8.7 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Zn_clus PF00172.18 EGD86272.2 - 7.5e-09 35.6 10.7 1.1e-08 35.0 10.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.9 EGD86272.2 - 9.8 5.7 11.5 7.1 6.2 5.0 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Aldose_epim PF01263.20 EGD86273.1 - 1.7e-57 195.0 0.0 1.9e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Glyoxalase_6 PF18029.1 EGD86275.1 - 2.3e-06 28.4 0.0 3.2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EGD86275.1 - 4.1e-05 23.8 0.0 8.2e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EGD86275.1 - 0.035 14.0 0.0 0.086 12.8 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EGD86275.1 - 0.051 13.9 0.0 0.48 10.7 0.0 2.0 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily QRPTase_C PF01729.19 EGD86276.1 - 1.3e-47 161.8 1.0 2.3e-25 89.3 0.1 2.1 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EGD86276.1 - 4.6e-23 81.1 0.0 1.1e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Mto2_bdg PF12808.7 EGD86277.1 - 4.8e-30 103.6 29.1 1.7e-19 69.8 20.1 10.6 12 2 1 13 13 13 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Cnn_1N PF07989.11 EGD86277.1 - 2.3e-22 78.9 9.5 2.3e-22 78.9 9.5 12.0 9 2 5 14 14 14 2 Centrosomin N-terminal motif 1 Fib_alpha PF08702.10 EGD86277.1 - 0.00078 19.7 7.8 0.00078 19.7 7.8 7.9 4 1 3 8 8 8 1 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EGD86277.1 - 0.19 11.8 0.0 0.19 11.8 4.1 8.5 4 1 3 8 8 8 0 Protein of unknown function (DUF1664) DUF2935 PF11155.8 EGD86277.1 - 1.2 9.5 11.1 6.4 7.1 0.5 5.8 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) Gemini_AL2 PF01440.16 EGD86277.1 - 5.6 7.4 8.7 2.4 8.6 4.3 2.5 2 0 0 2 2 2 0 Geminivirus AL2 protein TPPII_N PF12583.8 EGD86277.1 - 8.2 7.0 10.9 0.14 12.7 0.9 3.1 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal Sec7 PF01369.20 EGD86278.1 - 1.6e-28 99.7 0.0 3e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EGD86278.1 - 5.7e-20 71.9 0.0 1.2e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain COesterase PF00135.28 EGD86279.2 - 2.8e-19 69.4 0.0 4e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Glyco_hydro_26 PF02156.15 EGD86279.2 - 0.24 10.8 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 FAD_binding_3 PF01494.19 EGD86282.1 - 1e-15 57.9 0.0 1.8e-09 37.3 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGD86282.1 - 4.1e-07 30.1 0.0 9.3e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGD86282.1 - 1.7e-06 27.5 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGD86282.1 - 1.5e-05 25.4 0.0 0.00094 19.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGD86282.1 - 0.00013 21.6 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGD86282.1 - 0.0084 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PQQ PF01011.21 EGD86282.1 - 0.0087 16.0 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 PQQ enzyme repeat HI0933_like PF03486.14 EGD86282.1 - 0.081 11.6 0.0 0.27 9.9 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 EGD86282.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 EGD86282.1 - 0.14 11.2 0.0 0.29 10.1 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EGD86282.1 - 0.2 10.9 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TAS2R PF05296.13 EGD86283.2 - 0.04 13.0 1.1 0.065 12.3 1.1 1.2 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) MFS_1 PF07690.16 EGD86284.1 - 4.3e-34 118.0 27.8 6.6e-34 117.4 27.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EGD86284.1 - 0.0059 16.0 21.8 0.68 9.2 21.8 2.2 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PP28 PF10252.9 EGD86285.2 - 1.6e-28 99.0 20.3 1.6e-28 99.0 20.3 4.1 3 2 1 4 4 4 1 Casein kinase substrate phosphoprotein PP28 Coilin_N PF15862.5 EGD86285.2 - 0.21 11.4 0.1 0.21 11.4 0.1 3.6 3 1 1 4 4 4 0 Coilin N-terminus MFS_1 PF07690.16 EGD86286.1 - 2.5e-18 66.1 38.0 2.5e-18 66.1 38.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 EGD86287.1 - 3.1e-12 46.8 0.0 4.3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGD86287.1 - 4e-09 36.8 0.0 7.4e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGD86287.1 - 9.3e-08 32.1 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD86287.1 - 7.9e-06 25.8 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGD86287.1 - 0.0021 18.2 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 EGD86287.1 - 0.025 14.3 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 EGD86287.1 - 0.11 13.2 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_20 PF00982.21 EGD86288.2 - 6.7e-148 493.3 0.0 8.7e-148 492.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGD86288.2 - 8.1e-82 273.8 0.0 1.8e-81 272.7 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EGD86288.2 - 0.00027 20.7 0.0 0.81 9.4 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase NTP_transf_2 PF01909.23 EGD86289.1 - 0.17 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain LETM1 PF07766.13 EGD86290.1 - 1.1e-09 38.1 0.3 2.4e-05 23.8 0.1 2.3 1 1 1 2 2 2 2 LETM1-like protein N_BRCA1_IG PF16158.5 EGD86291.1 - 1.4e-29 102.8 0.0 3.1e-29 101.7 0.0 1.7 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EGD86291.1 - 2.2e-17 62.6 35.1 1.3e-06 28.1 8.9 3.5 3 0 0 3 3 3 3 Zinc finger, ZZ type C1_2 PF03107.16 EGD86291.1 - 0.53 10.7 42.1 0.064 13.6 9.5 4.0 4 0 0 4 4 4 0 C1 domain Btz PF09405.10 EGD86293.2 - 2.5e-23 82.8 4.6 2.5e-23 82.8 4.6 2.8 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding UBA2_C PF16195.5 EGD86293.2 - 0.74 10.5 7.0 0.1 13.3 1.0 2.8 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus SUIM_assoc PF16619.5 EGD86293.2 - 6.5 6.9 44.2 0.16 12.0 5.4 4.9 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 EGD86294.1 - 3.2e-25 87.7 0.0 4.2e-14 52.1 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGD86294.1 - 0.00027 21.0 0.2 0.056 13.6 0.0 3.3 3 1 0 3 3 3 1 RNA recognition motif Spt5_N PF11942.8 EGD86294.1 - 0.04 14.9 6.3 0.11 13.5 6.3 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Nup35_RRM_2 PF14605.6 EGD86294.1 - 0.099 12.7 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ino80_Iec3 PF14612.6 EGD86295.1 - 2e-73 248.0 7.5 2.9e-73 247.5 7.5 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling DUF2433 PF10360.9 EGD86295.1 - 0.17 12.0 0.8 0.49 10.5 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) FAD_binding_4 PF01565.23 EGD86296.1 - 8.7e-19 67.6 0.3 1.6e-18 66.8 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGD86296.1 - 3.5e-10 39.8 0.9 8.8e-10 38.5 0.1 2.1 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 EGD86296.1 - 0.17 11.2 0.4 0.43 9.9 0.4 1.7 1 1 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding GFA PF04828.14 EGD86297.1 - 8.9e-21 74.0 2.8 1.2e-20 73.6 2.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Dynamin_M PF01031.20 EGD86298.2 - 8.6e-06 25.2 0.1 0.00032 20.0 0.1 2.2 1 1 0 1 1 1 1 Dynamin central region S-antigen PF05756.11 EGD86298.2 - 0.066 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 S-antigen protein KH_6 PF15985.5 EGD86299.2 - 2.2e-06 27.9 0.1 3.9e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 KH domain Oxysterol_BP PF01237.18 EGD86300.2 - 2.1e-93 313.1 0.8 4.6e-57 193.5 0.1 2.3 1 1 1 2 2 2 2 Oxysterol-binding protein Plus-3 PF03126.18 EGD86301.1 - 2e-29 102.3 0.0 1.5e-28 99.4 0.0 2.4 3 0 0 3 3 3 1 Plus-3 domain Chitin_synth_1 PF01644.17 EGD86304.2 - 2.5e-73 245.4 0.0 4e-73 244.8 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGD86304.2 - 6.5e-30 102.9 0.0 1.2e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGD86304.2 - 1.1e-20 73.8 4.2 4.1e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGD86304.2 - 0.00069 19.6 20.5 0.0024 17.8 15.5 3.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF4199 PF13858.6 EGD86304.2 - 8.7 6.7 25.7 0.089 13.2 13.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Lipase_GDSL_2 PF13472.6 EGD86305.1 - 6e-11 43.1 0.1 2e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGD86305.1 - 2.1e-05 24.6 0.0 6.2e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TMEM234 PF10639.9 EGD86306.1 - 5.9e-33 113.4 2.5 3e-32 111.1 2.5 1.8 1 1 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 EGD86306.1 - 0.00048 20.3 9.1 0.015 15.5 5.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family MFS_MOT1 PF16983.5 EGD86307.1 - 2.8e-61 204.8 32.9 2.1e-32 111.8 8.7 3.2 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily PhyH PF05721.13 EGD86309.1 - 1e-42 146.8 0.0 1.3e-42 146.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EGD86309.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase UTP15_C PF09384.10 EGD86310.1 - 1.1e-51 174.3 0.0 2e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EGD86310.1 - 8.5e-18 64.4 4.2 0.00042 21.1 0.1 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD86310.1 - 4e-07 30.3 0.1 0.13 12.6 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGD86310.1 - 0.00063 19.4 1.2 0.016 14.8 0.1 2.5 1 1 1 2 2 2 1 PQQ-like domain RAB3GAP2_N PF14655.6 EGD86310.1 - 0.019 14.3 0.1 6.3 5.9 0.1 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AAA_12 PF13087.6 EGD86312.1 - 8.9e-32 110.3 0.0 1.6e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGD86312.1 - 3.5e-18 66.3 0.1 1.1e-11 45.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGD86312.1 - 5.6e-08 33.2 0.0 1.1e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EGD86312.1 - 0.00042 19.9 0.0 0.0014 18.3 0.0 1.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 EGD86312.1 - 0.00066 19.5 0.0 0.0026 17.5 0.0 2.0 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 EGD86312.1 - 0.0056 16.5 0.1 0.76 9.5 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EGD86312.1 - 0.062 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Cwf_Cwc_15 PF04889.12 EGD86312.1 - 4.4 7.0 10.0 6.9 6.3 10.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 EGD86312.1 - 4.4 6.3 9.8 6.7 5.7 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Fungal_trans PF04082.18 EGD86314.1 - 4e-12 45.7 0.1 5.2e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD86314.1 - 2.2e-10 40.5 10.5 4.4e-10 39.5 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBR PF01485.21 EGD86315.1 - 0.00045 20.4 6.7 0.00045 20.4 6.7 5.6 4 1 0 4 4 4 1 IBR domain, a half RING-finger domain IL4 PF00727.18 EGD86315.1 - 0.02 15.1 0.0 8.4 6.7 0.0 2.8 2 0 0 2 2 2 0 Interleukin 4 VWA_2 PF13519.6 EGD86315.1 - 0.026 15.2 0.0 0.064 13.9 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain RecR PF02132.15 EGD86315.1 - 4.5 6.9 9.1 1.5 8.4 1.5 3.9 3 1 0 3 3 3 0 RecR protein OTU PF02338.19 EGD86316.1 - 5.3e-07 30.2 0.0 8.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.8 EGD86316.1 - 0.11 12.9 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Cyclophil_like2 PF18050.1 EGD86316.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Cyclophilin-like family APC_r PF05923.12 EGD86316.1 - 0.24 11.2 1.0 0.47 10.2 1.0 1.5 1 0 0 1 1 1 0 APC repeat BAH PF01426.18 EGD86317.2 - 1.4e-17 63.6 0.8 3.4e-17 62.4 0.8 1.7 1 0 0 1 1 1 1 BAH domain Bromodomain PF00439.25 EGD86317.2 - 1.9e-16 59.9 0.3 4.2e-16 58.8 0.3 1.6 1 0 0 1 1 1 1 Bromodomain CDC45 PF02724.14 EGD86317.2 - 0.027 12.8 6.8 0.036 12.4 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein FRG2 PF15315.6 EGD86317.2 - 1.2 9.3 6.0 2 8.6 6.0 1.4 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 FAM176 PF14851.6 EGD86317.2 - 1.9 8.1 4.6 4.7 6.9 4.6 1.6 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 EGD86317.2 - 2.9 5.9 7.7 4.1 5.4 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 EGD86317.2 - 5.3 6.1 8.7 8.8 5.4 8.7 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein MRC1 PF09444.10 EGD86318.2 - 1.7e-41 142.2 21.6 1.7e-41 142.2 21.6 6.1 5 2 1 6 6 6 1 MRC1-like domain Hydrolase_like PF13242.6 EGD86320.1 - 0.0002 21.3 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Plus-3 PF03126.18 EGD86320.1 - 0.087 13.4 0.0 0.38 11.3 0.0 2.0 2 0 0 2 2 2 0 Plus-3 domain MIF4G PF02854.19 EGD86321.1 - 7.9e-24 84.5 1.1 1.2e-22 80.6 0.9 2.3 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 EGD86321.1 - 1.3e-17 63.7 0.0 4.7e-17 62.0 0.0 2.0 1 0 0 1 1 1 1 MA3 domain EST1_DNA_bind PF10373.9 EGD86321.1 - 0.00013 21.6 0.3 0.00027 20.5 0.3 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain SRP14 PF02290.15 EGD86322.1 - 7.8e-29 99.9 0.0 1e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein EI24 PF07264.11 EGD86324.1 - 1.1e-11 45.3 5.4 2.5e-09 37.6 5.4 2.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3742 PF12553.8 EGD86324.1 - 0.5 10.5 0.1 0.5 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) Sugar_tr PF00083.24 EGD86326.1 - 2.3e-43 148.7 22.3 9.5e-28 97.2 6.5 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 EGD86326.1 - 2.7e-22 79.2 26.0 1.2e-20 73.7 23.4 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily CopD PF05425.13 EGD86326.1 - 6 7.3 9.9 1.4 9.3 0.0 3.6 4 0 0 4 4 4 0 Copper resistance protein D ATF7IP_BD PF16788.5 EGD86327.2 - 0.98 9.5 10.0 0.21 11.7 6.1 1.8 1 1 1 2 2 2 0 ATF-interacting protein binding domain DUF2841 PF11001.8 EGD86329.2 - 1.6e-31 108.9 0.1 2.3e-31 108.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF5638 PF18688.1 EGD86329.2 - 0.1 12.9 0.2 0.29 11.5 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5638) CorA PF01544.18 EGD86329.2 - 0.11 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TNT PF14021.6 EGD86330.1 - 3e-28 98.2 0.0 4.5e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin FmdA_AmdA PF03069.15 EGD86331.2 - 1.1e-48 166.0 0.0 1.2e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Pro_isomerase PF00160.21 EGD86332.2 - 1.1e-27 97.3 0.3 2.1e-27 96.3 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EGD86332.2 - 9e-05 22.3 10.9 0.00021 21.1 2.5 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGD86332.2 - 0.00018 21.1 1.5 0.00018 21.1 1.5 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGD86332.2 - 0.0027 17.8 1.9 0.4 10.9 1.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGD86332.2 - 0.0078 16.8 8.6 0.22 12.2 7.5 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGD86332.2 - 0.031 14.5 0.7 0.031 14.5 0.7 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGD86332.2 - 0.26 11.6 7.9 0.9 9.9 6.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGD86332.2 - 0.38 11.7 6.3 0.37 11.7 2.9 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGD86332.2 - 5.3 6.8 6.7 20 4.9 0.5 3.1 2 1 1 3 3 3 0 TPR repeat Tyr_Deacylase PF02580.16 EGD86333.1 - 3.1e-52 176.9 0.1 3.5e-52 176.7 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.15 EGD86334.1 - 5.6e-87 291.0 14.6 8.5e-87 290.4 14.6 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EGD86334.1 - 2.6e-42 144.0 11.5 6.2e-42 142.8 11.5 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CLZ PF16526.5 EGD86334.1 - 0.015 15.6 1.9 0.041 14.2 0.5 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2373 PF10180.9 EGD86334.1 - 0.061 13.2 4.7 0.16 11.8 4.7 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.6 EGD86334.1 - 0.26 11.7 6.9 0.068 13.5 2.1 2.5 2 0 0 2 2 2 0 Syntaxin-like protein zf-C2H2 PF00096.26 EGD86336.1 - 0.00046 20.5 5.3 0.32 11.5 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EGD86336.1 - 0.00091 19.4 0.2 0.0013 18.9 0.2 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EGD86336.1 - 0.013 16.3 3.7 0.07 14.0 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger APH PF01636.23 EGD86337.2 - 3.7e-05 23.8 0.0 6.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DNA_binding_1 PF01035.20 EGD86340.1 - 2.5e-24 85.2 0.0 3.7e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Rubella_Capsid PF05750.11 EGD86340.1 - 0.004 16.8 0.1 0.0066 16.1 0.0 1.4 2 0 0 2 2 2 1 Rubella capsid protein Pyr_redox_2 PF07992.14 EGD86342.1 - 7.9e-68 228.8 7.2 7.9e-68 228.8 7.2 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGD86342.1 - 2.3e-39 134.0 0.1 6.4e-39 132.6 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGD86342.1 - 3.7e-21 75.5 12.0 1.3e-20 73.7 1.1 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGD86342.1 - 6.5e-11 42.2 10.3 1.5e-10 41.1 0.3 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGD86342.1 - 1.4e-09 38.1 4.2 2.8e-05 24.3 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGD86342.1 - 2.7e-08 33.3 13.5 3e-07 29.9 4.7 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGD86342.1 - 6.7e-08 32.1 7.0 1e-05 25.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGD86342.1 - 8.7e-07 28.4 2.5 8.7e-07 28.4 2.5 2.8 2 1 1 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 EGD86342.1 - 1.4e-06 27.7 5.0 0.0037 16.6 0.4 3.2 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 EGD86342.1 - 3.7e-06 26.3 0.7 0.094 11.8 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EGD86342.1 - 7.1e-06 25.0 13.3 0.0006 18.6 1.4 4.0 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.24 EGD86342.1 - 3.6e-05 23.5 14.1 0.046 13.3 0.9 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGD86342.1 - 4.7e-05 22.7 4.8 0.00043 19.6 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EGD86342.1 - 0.00031 19.9 2.4 0.017 14.2 0.1 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein THF_DHG_CYH_C PF02882.19 EGD86342.1 - 0.0048 16.2 1.4 0.14 11.5 0.1 3.2 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_3 PF01494.19 EGD86342.1 - 0.0087 15.3 11.2 0.2 10.8 1.3 3.5 3 1 1 4 4 4 2 FAD binding domain FMO-like PF00743.19 EGD86342.1 - 0.13 10.7 1.4 0.39 9.1 0.1 2.3 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.6 EGD86342.1 - 0.16 12.4 2.7 1.4 9.4 0.1 3.1 3 0 0 3 3 3 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 EGD86342.1 - 2 7.2 7.3 1.2 8.0 0.9 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 EGD86342.1 - 9 6.1 8.4 0.43 10.5 1.1 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PGM_PMM_I PF02878.16 EGD86344.1 - 2.1e-36 124.7 0.0 4.1e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EGD86344.1 - 6.9e-25 87.7 0.0 1.6e-24 86.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EGD86344.1 - 9.2e-16 58.1 0.0 1.7e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EGD86344.1 - 1.8e-07 31.2 0.0 7e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AdoMet_MTase PF07757.13 EGD86344.1 - 0.038 14.3 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase FA_desaturase PF00487.24 EGD86345.1 - 4.7e-25 88.9 30.4 7e-25 88.3 30.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGD86345.1 - 6.5e-11 42.2 0.0 1.9e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain PI-TkoII_IV PF18714.1 EGD86345.1 - 0.17 11.3 0.2 0.4 10.1 0.1 1.6 2 0 0 2 2 2 0 DNA polymerase II intein Domain IV CUE PF02845.16 EGD86346.1 - 1.4e-10 40.7 0.1 2.7e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 CUE domain Ribosomal_S10 PF00338.22 EGD86347.1 - 1e-26 93.0 0.3 1.2e-26 92.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH_4 PF18044.1 EGD86348.1 - 7.5e-09 35.2 2.5 1.5e-08 34.3 2.5 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EGD86348.1 - 6.4e-06 25.9 2.7 1.4e-05 24.9 2.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGD86348.1 - 8.9e-06 25.6 6.3 1.8e-05 24.6 6.3 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 EGD86348.1 - 0.058 14.1 1.2 0.12 13.1 1.2 1.5 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 EGD86348.1 - 0.097 13.2 1.3 0.22 12.0 1.3 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger ELYS PF13934.6 EGD86349.1 - 6.4e-66 222.5 0.1 8.2e-66 222.1 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly Peptidase_M75 PF09375.10 EGD86349.1 - 0.073 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Imelysin SMC_N PF02463.19 EGD86350.2 - 3.2e-31 108.5 23.6 1.5e-30 106.3 23.6 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGD86350.2 - 3.4e-24 85.4 0.0 9e-24 84.0 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 EGD86350.2 - 3e-08 33.8 20.7 3e-08 33.8 20.7 3.5 2 2 0 2 2 1 1 AAA ATPase domain AAA_23 PF13476.6 EGD86350.2 - 1.8e-06 28.6 25.3 1.8e-06 28.6 25.3 6.3 2 2 2 4 4 2 1 AAA domain AAA_21 PF13304.6 EGD86350.2 - 1e-05 25.5 0.0 3.9e-05 23.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Tektin PF03148.14 EGD86350.2 - 0.00012 21.0 15.1 0.00012 21.0 15.1 5.3 3 1 1 5 5 5 2 Tektin family AAA_29 PF13555.6 EGD86350.2 - 0.00046 19.9 0.0 0.00091 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Filament PF00038.21 EGD86350.2 - 0.00075 19.2 13.0 0.00075 19.2 13.0 5.1 2 2 1 4 4 3 2 Intermediate filament protein Fib_alpha PF08702.10 EGD86350.2 - 0.0018 18.4 7.2 0.0018 18.4 7.2 6.4 2 2 5 7 7 7 2 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 EGD86350.2 - 0.42 10.7 16.5 0.041 13.9 1.0 4.6 3 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 EGD86350.2 - 0.47 9.8 77.3 0.015 14.6 11.2 4.9 2 2 2 4 4 4 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 EGD86350.2 - 1.7 8.9 32.2 0.19 12.0 0.4 6.8 6 2 1 7 7 7 0 Bacterial protein of unknown function (DUF948) Fungal_trans PF04082.18 EGD86351.2 - 1.1e-09 37.7 0.7 5.2e-09 35.5 0.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD86351.2 - 1.3e-07 31.6 5.1 2.6e-07 30.7 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trypan_PARP PF05887.11 EGD86351.2 - 0.055 13.4 12.9 0.11 12.5 12.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.14 EGD86351.2 - 0.57 8.4 6.6 0.82 7.9 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Suc_Fer-like PF06999.12 EGD86352.1 - 1.5e-68 230.5 0.0 1.8e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Ribonuc_L-PSP PF01042.21 EGD86353.1 - 3.5e-10 39.9 0.1 5.8e-10 39.2 0.1 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.32 EGD86354.2 - 2e-06 28.4 5.5 0.29 12.1 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Fimbrillin_C PF15495.6 EGD86354.2 - 0.13 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal RNA_pol_N PF01194.17 EGD86355.2 - 3.3e-31 107.3 1.4 4.4e-31 107.0 1.4 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 EGD86355.2 - 0.036 14.3 0.8 0.062 13.6 0.8 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) GDPD PF03009.17 EGD86355.2 - 0.1 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Fer4_13 PF13370.6 EGD86356.2 - 0.48 11.0 3.6 4.7 7.8 0.0 3.8 3 2 1 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I Sugar_tr PF00083.24 EGD86357.2 - 5.8e-97 325.4 20.9 6.5e-97 325.2 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGD86357.2 - 1.1e-19 70.6 34.7 5.8e-11 41.9 6.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.6 EGD86358.1 - 5.2e-34 117.5 0.0 4e-32 111.4 0.0 2.5 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGD86358.1 - 2.9e-14 53.4 0.0 5.3e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GxGYxYP_C PF14323.6 EGD86358.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain MFS_1 PF07690.16 EGD86359.1 - 1.4e-36 126.2 49.8 1.4e-36 126.2 49.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.19 EGD86359.1 - 0.00022 20.1 1.2 0.00022 20.1 1.2 2.6 2 1 0 2 2 2 1 LacY proton/sugar symporter DUF2254 PF10011.9 EGD86359.1 - 0.00097 18.1 0.0 0.0021 17.0 0.0 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) Sarcolipin PF05366.11 EGD86359.1 - 0.061 13.0 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 Sarcolipin DNA_primase_S PF01896.19 EGD86360.1 - 1.3e-60 204.5 0.0 2.1e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 DNA primase small subunit MAM33 PF02330.16 EGD86361.1 - 8e-75 251.4 1.4 9.4e-75 251.2 1.4 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3567 PF12091.8 EGD86361.1 - 0.13 12.4 0.6 0.82 9.8 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3567) CobW_C PF07683.14 EGD86362.2 - 3.5e-22 78.1 0.0 1e-17 63.8 0.0 2.3 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain NicO PF03824.16 EGD86362.2 - 2 7.7 3.5 2.8 7.2 3.5 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein CENP-B_dimeris PF09026.10 EGD86362.2 - 6 7.3 17.4 0.18 12.2 7.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SelP_N PF04592.14 EGD86362.2 - 9.6 5.5 11.2 18 4.7 11.2 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Tma16 PF11176.8 EGD86363.2 - 1e-36 126.0 0.6 1.2e-36 125.8 0.6 1.0 1 0 0 1 1 1 1 Translation machinery-associated protein 16 betaPIX_CC PF16523.5 EGD86363.2 - 0.19 11.6 2.1 1.1 9.1 2.1 2.2 1 1 0 1 1 1 0 betaPIX coiled coil XPG_I PF00867.18 EGD86364.2 - 2e-22 79.3 0.0 4.7e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EGD86364.2 - 1.8e-06 28.3 0.0 0.00013 22.4 0.0 3.1 3 0 0 3 3 3 1 XPG N-terminal domain XPG_I_2 PF12813.7 EGD86364.2 - 0.0043 16.6 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_14 PF13428.6 EGD86364.2 - 0.13 13.2 0.0 0.34 11.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGD86364.2 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Fig1 PF12351.8 EGD86366.1 - 1.5e-58 197.9 4.3 1.5e-58 197.9 4.3 1.9 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EGD86366.1 - 2.5e-06 27.3 8.9 4.6e-06 26.4 8.9 1.3 1 1 0 1 1 1 1 SUR7/PalI family MLTD_N PF06474.12 EGD86366.1 - 1.8 8.8 7.4 0.66 10.2 3.3 2.3 2 0 0 2 2 2 0 MltD lipid attachment motif DUF898 PF05987.13 EGD86366.1 - 9.6 5.1 11.4 0.75 8.8 5.8 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) HAD_SAK_1 PF10307.9 EGD86368.2 - 0.12 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins zf-RING_2 PF13639.6 EGD86369.1 - 4.5e-08 33.3 9.2 8.1e-08 32.5 9.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGD86369.1 - 1.5e-05 24.7 8.8 2.4e-05 24.1 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGD86369.1 - 2.5e-05 24.0 8.7 4e-05 23.4 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGD86369.1 - 0.00011 22.4 8.8 0.00043 20.5 8.8 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGD86369.1 - 0.00011 21.9 8.3 0.00021 21.1 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGD86369.1 - 0.0089 15.9 6.3 0.015 15.1 6.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGD86369.1 - 0.46 10.5 5.5 0.9 9.5 5.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 EGD86369.1 - 0.56 10.0 7.0 1.2 8.9 7.0 1.5 1 0 0 1 1 1 0 RING-like zinc finger Drc1-Sld2 PF11719.8 EGD86370.1 - 3e-81 274.3 26.2 3.4e-81 274.1 26.2 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein DUF2855 PF11017.8 EGD86370.1 - 0.12 12.1 1.7 0.22 11.3 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) 2-oxoacid_dh PF00198.23 EGD86371.1 - 4.3e-81 271.8 0.0 8e-81 270.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGD86371.1 - 8.9e-16 57.5 1.4 8.9e-16 57.5 1.4 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme SAGA-Tad1 PF12767.7 EGD86371.1 - 0.071 12.8 2.1 0.053 13.2 0.8 1.6 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit GCV_H PF01597.19 EGD86371.1 - 0.092 12.6 0.5 0.21 11.5 0.5 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein Presenilin PF01080.17 EGD86371.1 - 1.9 7.2 4.2 2.7 6.7 4.2 1.1 1 0 0 1 1 1 0 Presenilin FAP PF07174.11 EGD86371.1 - 2 7.8 12.6 3.1 7.2 12.6 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Ndc1_Nup PF09531.10 EGD86371.1 - 5.9 5.5 6.3 8.4 5.0 6.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Complex1_LYR PF05347.15 EGD86372.2 - 3.7e-07 30.1 0.4 6.1e-07 29.4 0.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Histone_H2A_C PF16211.5 EGD86373.1 - 3.1e-18 65.2 0.4 5.4e-18 64.4 0.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGD86373.1 - 3.1e-16 59.9 0.0 3.8e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGD86373.1 - 2.9e-05 24.3 0.0 3.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGD86374.1 - 2.5e-19 69.9 0.9 3.2e-19 69.6 0.9 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGD86374.1 - 0.00014 22.0 0.1 0.00014 22.0 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGD86374.1 - 0.0036 17.8 0.0 0.0059 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Peptidase_C54 PF03416.19 EGD86375.2 - 1.8e-65 221.1 0.0 3e-65 220.4 0.0 1.4 2 0 0 2 2 2 1 Peptidase family C54 NUDE_C PF04880.13 EGD86375.2 - 0.071 13.6 6.4 0.13 12.7 6.4 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region MGC-24 PF05283.11 EGD86375.2 - 0.22 12.0 3.9 0.36 11.3 3.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin R3H PF01424.22 EGD86376.1 - 2.3e-11 43.5 0.0 6.8e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 EGD86376.1 - 5.4e-09 35.8 0.4 1.5e-08 34.4 0.4 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGD86376.1 - 0.0034 17.4 0.2 0.0034 17.4 0.2 3.2 4 0 0 4 4 4 1 G-patch domain DnaJ PF00226.31 EGD86377.1 - 3.5e-25 87.9 0.3 9.8e-25 86.5 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.7 EGD86377.1 - 2.4e-13 50.0 7.0 8.9e-10 38.6 2.3 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGD86377.1 - 3.5e-12 46.3 8.9 2.4e-10 40.4 5.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGD86377.1 - 5.7e-10 39.4 6.1 0.0002 21.6 1.5 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EGD86377.1 - 1.9e-07 31.2 6.3 0.004 17.5 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD86377.1 - 7.8e-07 29.4 4.7 0.0089 16.8 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Actin_micro PF17003.5 EGD86377.1 - 0.00073 18.8 0.5 0.28 10.3 0.1 2.2 2 0 0 2 2 2 2 Putative actin-like family zf-C2H2_6 PF13912.6 EGD86377.1 - 0.0011 18.9 9.6 0.12 12.4 3.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EGD86377.1 - 0.0058 17.3 1.4 1.9 9.2 0.1 2.7 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats LIM PF00412.22 EGD86377.1 - 0.022 15.0 2.0 3.5 7.9 0.6 2.4 2 0 0 2 2 2 0 LIM domain DUF3449 PF11931.8 EGD86377.1 - 0.028 14.2 1.7 0.028 14.2 1.7 3.0 3 2 0 3 3 3 0 Domain of unknown function (DUF3449) MRNIP PF15749.5 EGD86377.1 - 0.031 15.0 2.7 0.031 15.0 2.7 2.9 2 1 0 2 2 2 0 MRN-interacting protein zf-H2C2_2 PF13465.6 EGD86377.1 - 0.15 12.5 1.7 2.1 8.9 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.15 EGD86377.1 - 0.17 11.9 0.3 27 4.9 0.0 2.4 2 0 0 2 2 2 0 BED zinc finger zf-MYST PF17772.1 EGD86377.1 - 0.18 11.4 0.2 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 MYST family zinc finger domain DUF2256 PF10013.9 EGD86377.1 - 0.18 11.9 0.8 21 5.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Adeno_E4 PF05385.11 EGD86378.1 - 0.19 11.9 0.4 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Mastadenovirus early E4 13 kDa protein Cwf_Cwc_15 PF04889.12 EGD86378.1 - 1.1 8.9 10.6 0.73 9.5 6.1 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein YccV-like PF08755.11 EGD86379.1 - 5.9e-30 103.7 0.3 2.6e-29 101.6 0.1 2.1 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 EGD86379.1 - 8.5e-15 54.7 0.0 1.4e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 EGD86379.1 - 7.7e-06 25.7 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD86379.1 - 0.0011 18.7 0.0 0.0029 17.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 EGD86379.1 - 0.003 18.0 0.1 0.0063 17.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A 23S_rRNA_IVP PF05635.11 EGD86379.1 - 0.047 14.0 0.1 0.15 12.4 0.1 1.8 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein SPX PF03105.19 EGD86380.2 - 5.9e-45 154.8 0.1 1.1e-44 153.9 0.1 1.4 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 EGD86380.2 - 8.9e-07 28.7 9.3 1.8e-06 27.7 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGD86380.2 - 5.9e-06 26.3 10.5 5.9e-06 26.3 10.5 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGD86380.2 - 1.4e-05 24.9 10.3 4e-05 23.5 10.3 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGD86380.2 - 2.4e-05 24.1 10.8 6.3e-05 22.8 10.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGD86380.2 - 0.00016 22.0 12.5 0.00039 20.7 12.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGD86380.2 - 0.0003 20.6 12.1 0.00076 19.3 12.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD86380.2 - 0.0017 18.3 10.9 0.0045 17.0 10.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGD86380.2 - 0.011 15.8 3.4 0.023 14.7 3.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGD86380.2 - 0.012 15.4 9.7 0.041 13.7 9.8 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TerY_C PF15616.6 EGD86380.2 - 0.067 13.3 0.6 0.14 12.3 0.6 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.6 EGD86380.2 - 0.18 11.6 7.8 0.029 14.2 3.4 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGD86380.2 - 0.44 10.9 9.8 1.4 9.2 9.8 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-P11 PF03854.14 EGD86380.2 - 0.54 10.0 8.4 13 5.6 8.6 2.4 1 1 1 2 2 2 0 P-11 zinc finger Nrap_D5 PF17406.2 EGD86383.1 - 1.9e-50 170.8 0.1 4.7e-50 169.5 0.1 1.7 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 EGD86383.1 - 4.5e-50 169.4 0.0 7.4e-48 162.2 0.0 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D4 PF17405.2 EGD86383.1 - 2.3e-42 144.8 0.4 4.6e-42 143.8 0.4 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 EGD86383.1 - 3.2e-41 140.9 0.4 5.6e-41 140.1 0.4 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 EGD86383.1 - 3.3e-39 134.5 0.0 6.4e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 EGD86383.1 - 3.9e-27 95.1 0.0 8.9e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 Fibroin_P25 PF07294.11 EGD86383.1 - 0.069 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Fibroin P25 Spc7 PF08317.11 EGD86383.1 - 0.17 10.7 0.1 0.31 9.9 0.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Cys_Met_Meta_PP PF01053.20 EGD86384.2 - 4.4e-18 65.0 0.0 1.1e-17 63.6 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MRP-L20 PF12824.7 EGD86386.1 - 7.2e-58 195.4 3.2 8.3e-58 195.2 3.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 EGD86386.1 - 0.00087 19.4 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Neugrin Pkinase PF00069.25 EGD86387.1 - 1.6e-05 24.4 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGD86387.1 - 0.00031 20.7 0.1 0.00031 20.7 0.1 2.7 3 1 0 3 3 3 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.6 EGD86387.1 - 0.0011 19.0 0.0 0.37 10.8 0.0 2.6 1 1 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Kdo PF06293.14 EGD86387.1 - 0.017 14.5 0.1 0.017 14.5 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGD86387.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Methyltransf_25 PF13649.6 EGD86389.1 - 3.3e-08 34.1 0.0 7.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD86389.1 - 0.0001 22.1 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD86389.1 - 0.00059 20.5 0.0 0.0011 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD86389.1 - 0.0087 16.7 0.0 0.021 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EGD86390.1 - 4.3e-27 94.8 0.0 6.4e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD86390.1 - 3.4e-16 59.5 0.0 8.6e-16 58.2 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD86390.1 - 1.6e-05 24.9 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGD86390.1 - 0.0015 17.7 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 EGD86390.1 - 0.17 11.7 1.6 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fanconi_A_N PF15865.5 EGD86390.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus AMP-binding PF00501.28 EGD86391.1 - 3.5e-68 230.1 0.0 5e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGD86391.1 - 7.7e-33 113.8 0.0 1.4e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EGD86391.1 - 1.2e-08 35.2 0.4 2.5e-08 34.2 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site PetN PF03742.14 EGD86391.1 - 0.32 10.9 2.2 0.8 9.6 2.2 1.7 1 0 0 1 1 1 0 PetN p450 PF00067.22 EGD86392.1 - 7.1e-65 219.5 0.0 9.6e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 EGD86393.1 - 2.7e-41 141.7 0.0 3.7e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGD86393.1 - 2.3e-15 57.0 0.0 3.3e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EGD86393.1 - 0.00058 20.3 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EGD86393.1 - 0.0024 17.4 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EGD86393.1 - 0.024 15.2 0.2 0.084 13.5 0.2 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EGD86393.1 - 0.085 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus MHC_II_alpha PF00993.20 EGD86393.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain AMP-binding PF00501.28 EGD86394.1 - 7.8e-72 242.2 0.0 1.2e-71 241.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGD86394.1 - 9.7e-56 188.8 0.0 1.5e-55 188.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EGD86394.1 - 1.4e-11 44.5 0.1 2.9e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EGD86394.1 - 4e-08 33.0 0.0 1.4e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGD86394.1 - 1e-05 24.7 0.0 2.3e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGD86394.1 - 0.23 10.8 0.0 0.71 9.2 0.0 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltransf_2 PF00891.18 EGD86395.2 - 3.5e-35 121.2 0.0 5.3e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 EGD86395.2 - 4.8e-05 24.0 0.0 0.0001 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD86395.2 - 0.00022 21.9 0.0 0.00074 20.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_C74 PF12387.8 EGD86395.2 - 0.03 13.8 0.0 0.09 12.2 0.0 1.7 2 0 0 2 2 2 0 Pestivirus NS2 peptidase MTS PF05175.14 EGD86395.2 - 0.047 13.2 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 EGD86396.1 - 1e-08 35.8 0.0 2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD86396.1 - 8.7e-07 29.6 0.0 1.5e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD86396.1 - 2.9e-05 24.6 0.0 6.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD86396.1 - 0.00013 21.8 0.0 0.00025 20.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD86396.1 - 0.0018 18.1 0.0 0.025 14.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 EGD86397.1 - 5e-54 183.6 26.5 1.4e-47 162.4 20.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGD86397.1 - 8e-11 40.9 3.6 1.4e-09 36.8 1.1 2.8 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EGD86397.1 - 5.5e-10 38.7 9.9 0.00011 21.2 3.4 3.6 2 1 1 3 3 3 3 MFS_1 like family MFS_3 PF05977.13 EGD86397.1 - 0.0012 17.3 1.0 0.0012 17.3 1.0 2.8 2 1 0 2 2 2 1 Transmembrane secretion effector UPRTase PF14681.6 EGD86398.1 - 1.6e-39 135.5 0.3 2e-39 135.2 0.3 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGD86398.1 - 0.0013 18.3 0.6 0.017 14.7 0.6 2.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 EGD86398.1 - 0.0021 17.6 0.2 0.0033 17.0 0.2 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase Peptidase_U4 PF03419.13 EGD86398.1 - 0.005 16.2 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Sporulation factor SpoIIGA PRELI PF04707.14 EGD86399.1 - 2.6e-23 82.6 0.0 2.8e-20 72.7 0.0 2.2 1 1 0 2 2 2 2 PRELI-like family His_Phos_1 PF00300.22 EGD86400.2 - 4.2e-37 127.7 0.1 5e-37 127.5 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 EGD86401.2 - 2.1e-73 246.9 0.0 2.7e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD86401.2 - 5.1e-37 127.6 0.0 7.3e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.11 EGD86401.2 - 1.8e-16 59.9 0.0 4.5e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EGD86401.2 - 1.7e-06 27.6 0.0 3.6e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGD86401.2 - 0.00014 21.5 0.2 0.00026 20.7 0.2 1.3 1 0 0 1 1 1 1 RIO1 family AdenylateSensor PF16579.5 EGD86401.2 - 0.00033 21.1 0.0 0.00067 20.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Haspin_kinase PF12330.8 EGD86401.2 - 0.00067 18.7 0.2 0.0015 17.5 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 EGD86401.2 - 0.0073 15.2 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 EGD86401.2 - 0.01 15.7 0.2 0.047 13.6 0.1 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGD86401.2 - 0.095 12.0 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGD86401.2 - 0.098 11.7 0.4 0.14 11.2 0.4 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 MARVEL PF01284.23 EGD86402.1 - 1.4e-22 80.3 9.5 1.7e-22 80.0 9.5 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF3431 PF11913.8 EGD86403.1 - 9e-39 133.5 0.0 1.2e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Pkinase_fungal PF17667.1 EGD86408.1 - 7e-137 456.5 0.0 8.7e-137 456.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGD86408.1 - 1.7e-08 34.1 0.0 2.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD86408.1 - 0.00062 19.1 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGD86408.1 - 0.096 12.6 0.0 1.7 8.5 0.0 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGD86408.1 - 0.22 11.1 0.0 0.56 9.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family His_Phos_1 PF00300.22 EGD86409.1 - 4e-12 46.2 0.0 2e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M28 PF04389.17 EGD86410.1 - 2.5e-32 112.2 0.2 4.4e-32 111.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGD86410.1 - 0.0013 18.5 0.3 0.0035 17.1 0.3 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1257 PF06868.11 EGD86410.1 - 0.081 13.2 0.2 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1257) RRM_1 PF00076.22 EGD86413.2 - 2.3e-51 171.5 0.1 2.2e-19 69.0 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGD86413.2 - 2.3e-36 123.5 0.0 7.1e-30 102.7 0.0 4.2 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGD86413.2 - 9.4e-05 22.3 0.0 0.041 13.9 0.1 3.5 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 EGD86413.2 - 0.0034 17.2 0.0 1.1 9.2 0.0 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF1866) Glyco_hydro_30C PF17189.4 EGD86413.2 - 0.012 15.8 0.6 0.026 14.8 0.6 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain TPR_14 PF13428.6 EGD86413.2 - 0.12 13.2 4.2 10 7.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat RE_AlwI PF09491.10 EGD86413.2 - 0.3 9.8 5.1 0.04 12.7 0.3 1.7 2 0 0 2 2 2 0 AlwI restriction endonuclease DEAD PF00270.29 EGD86415.1 - 3.2e-47 160.6 0.0 6.1e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD86415.1 - 5.9e-25 87.8 0.0 7e-24 84.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGD86415.1 - 1.2e-19 70.3 0.2 2.6e-19 69.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGD86415.1 - 0.00062 19.8 0.0 0.0019 18.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EGD86415.1 - 0.034 13.4 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Ribosomal_L22 PF00237.19 EGD86416.1 - 3.9e-28 97.7 0.2 8.7e-28 96.6 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Oxysterol_BP PF01237.18 EGD86418.1 - 1.5e-53 181.9 0.0 2.4e-51 174.7 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Cnd1_N PF12922.7 EGD86419.1 - 6.3e-58 195.3 0.0 1.6e-57 193.9 0.0 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 EGD86419.1 - 4.4e-06 26.5 1.4 0.034 14.4 0.0 4.9 4 1 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EGD86419.1 - 7.2e-06 26.3 0.2 0.037 14.4 0.0 3.9 3 1 2 5 5 5 3 HEAT repeats RTP1_C1 PF10363.9 EGD86419.1 - 0.0019 18.3 0.2 0.48 10.6 0.0 3.8 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 EGD86419.1 - 0.01 15.9 0.0 0.033 14.2 0.0 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 VHS PF00790.19 EGD86419.1 - 0.049 13.5 0.1 2.9 7.7 0.0 2.7 2 0 0 2 2 2 0 VHS domain DUF5442 PF17514.2 EGD86419.1 - 0.12 12.5 0.0 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5442) Pkinase PF00069.25 EGD86420.1 - 6e-41 140.6 0.0 2.9e-22 79.3 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGD86420.1 - 1.5e-14 53.9 0.0 1.1e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGD86420.1 - 0.0077 16.2 0.0 0.45 10.4 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGD86420.1 - 0.023 14.0 0.0 8 5.7 0.0 2.8 3 0 0 3 3 3 0 Kinase-like FTA2 PF13095.6 EGD86420.1 - 0.063 12.9 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGD86420.1 - 0.13 11.0 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase PCMT PF01135.19 EGD86421.1 - 7.1e-61 205.6 0.0 8.7e-61 205.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGD86421.1 - 1.3e-07 31.6 0.0 2.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD86421.1 - 2.3e-06 28.2 0.0 4.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD86421.1 - 3.4e-05 23.7 0.0 4.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD86421.1 - 0.00049 20.8 0.0 0.00077 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGD86421.1 - 0.0005 20.1 0.0 0.0008 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGD86421.1 - 0.005 16.4 0.0 0.0086 15.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EGD86421.1 - 0.0092 16.6 0.0 0.016 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EGD86421.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 EGD86421.1 - 0.031 13.7 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EGD86421.1 - 0.038 13.3 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EGD86421.1 - 0.14 11.0 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DnaJ PF00226.31 EGD86422.1 - 2.5e-22 78.8 0.9 7.7e-22 77.2 0.9 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 EGD86422.1 - 3.8e-20 70.3 0.1 0.00013 21.8 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGD86422.1 - 3.8e-18 64.5 1.3 8.7e-06 25.3 0.0 6.2 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGD86422.1 - 5.1e-15 55.4 0.3 0.0028 17.7 0.0 4.9 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGD86422.1 - 1.4e-12 47.3 0.8 0.041 14.7 0.2 6.9 3 3 4 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGD86422.1 - 1.6e-12 47.7 1.9 0.0081 16.6 0.1 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGD86422.1 - 1e-11 44.0 0.0 0.0077 16.4 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGD86422.1 - 1.3e-10 41.7 4.0 3e-06 27.8 0.2 4.8 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGD86422.1 - 3e-09 36.9 2.9 3.1 8.6 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGD86422.1 - 4.1e-09 36.0 0.7 0.047 13.4 0.0 4.3 3 1 1 4 4 4 3 TPR repeat TPR_17 PF13431.6 EGD86422.1 - 8.3e-07 29.0 2.0 0.005 17.1 0.1 6.1 7 2 0 7 7 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGD86422.1 - 2.6e-05 24.4 0.0 2.3 8.6 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat PknG_TPR PF16918.5 EGD86422.1 - 0.00067 18.5 0.2 0.0075 15.0 0.0 2.5 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat ANAPC3 PF12895.7 EGD86422.1 - 0.0007 19.8 4.6 4.3 7.6 0.0 4.8 5 1 2 7 7 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGD86422.1 - 0.001 19.0 0.4 27 5.1 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 EGD86422.1 - 0.019 15.0 1.8 6.6 6.8 0.0 3.9 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) HrpB1_HrpK PF09613.10 EGD86422.1 - 0.05 13.3 0.0 8.4 6.1 0.0 3.3 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) Alkyl_sulf_dimr PF14863.6 EGD86422.1 - 0.16 12.4 1.2 2.1 8.8 0.1 2.9 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation PTS_IIA PF02255.16 EGD86422.1 - 0.96 9.5 6.8 7.2 6.7 1.9 2.9 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit LMBR1 PF04791.16 EGD86422.1 - 1.2 8.0 2.8 2.7 6.8 1.8 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein PCRF PF03462.18 EGD86423.2 - 1.1e-34 120.0 1.6 2.6e-34 118.8 0.1 2.2 3 0 0 3 3 3 1 PCRF domain RF-1 PF00472.20 EGD86423.2 - 5.9e-34 116.5 1.0 5.9e-34 116.5 1.0 1.6 2 0 0 2 2 2 1 RF-1 domain Abdominal-A PF12407.8 EGD86423.2 - 0.49 10.0 9.1 0.97 9.1 9.1 1.4 1 0 0 1 1 1 0 Homeobox protein Mito_carr PF00153.27 EGD86424.1 - 4.6e-54 180.3 4.0 4.3e-23 81.0 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DEAD PF00270.29 EGD86425.1 - 2.7e-42 144.5 0.2 3.9e-42 144.0 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD86425.1 - 6.8e-28 97.2 0.8 6.4e-27 94.1 0.4 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 EGD86425.1 - 0.01 15.2 0.1 0.023 14.0 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit NUDIX PF00293.28 EGD86427.1 - 5.4e-13 49.1 1.1 1.1e-12 48.1 1.1 1.5 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EGD86427.1 - 0.00011 22.2 0.2 0.0013 18.7 0.2 2.3 1 1 0 1 1 1 1 NUDIX domain MFS_1 PF07690.16 EGD86432.2 - 8.6e-33 113.7 23.3 8.6e-33 113.7 23.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EGD86432.2 - 1.1e-06 28.2 0.7 1.1e-06 28.2 0.7 3.0 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Yae1_N PF09811.9 EGD86433.1 - 2.4e-12 46.3 0.6 5.5e-12 45.2 0.6 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF572 PF04502.13 EGD86434.2 - 8.7 5.9 37.8 0.21 11.2 0.7 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF572) SCO1-SenC PF02630.14 EGD86435.2 - 5.2e-42 142.9 0.2 4.3e-38 130.3 0.0 2.3 1 1 1 2 2 2 2 SCO1/SenC Phage_TAC_8 PF10666.9 EGD86435.2 - 0.046 14.0 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 FYTT PF07078.11 EGD86435.2 - 0.099 12.0 0.5 0.15 11.4 0.5 1.2 1 0 0 1 1 1 0 Forty-two-three protein MoaE PF02391.17 EGD86436.1 - 6.8e-37 126.2 0.1 8.3e-37 125.9 0.1 1.1 1 0 0 1 1 1 1 MoaE protein Ntox25 PF15530.6 EGD86436.1 - 0.2 11.8 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 25 SLAC1 PF03595.17 EGD86437.2 - 2.1e-94 316.4 48.3 2.7e-94 316.1 48.3 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel TRAF_BIRC3_bd PF16673.5 EGD86439.2 - 0.072 12.9 0.9 0.13 12.0 0.9 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Hep_59 PF07052.11 EGD86439.2 - 0.19 12.5 3.4 0.55 11.0 1.0 2.1 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 RRM_1 PF00076.22 EGD86440.2 - 4.2e-11 42.5 0.0 0.00015 21.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 EGD86440.2 - 1.6e-09 37.5 5.8 1.8e-09 37.3 3.8 2.0 2 0 0 2 2 2 1 G-patch domain zf-RanBP PF00641.18 EGD86440.2 - 4.6e-07 29.0 1.1 7.4e-07 28.4 1.1 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 EGD86440.2 - 0.00068 19.7 5.7 0.00084 19.4 2.8 2.5 2 0 0 2 2 2 1 G-patch domain Rad50_zn_hook PF04423.14 EGD86440.2 - 0.027 14.3 0.2 0.092 12.6 0.2 1.9 1 0 0 1 1 1 0 Rad50 zinc hook motif Candida_ALS PF05792.13 EGD86441.2 - 0.015 15.9 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 Candida agglutinin-like (ALS) Pkinase PF00069.25 EGD86441.2 - 0.076 12.4 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 EGD86442.1 - 0.00013 21.4 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3433 PF11915.8 EGD86443.1 - 2.6e-29 101.5 19.1 7e-22 77.7 5.6 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) RTA1 PF04479.13 EGD86444.2 - 9.1e-31 107.1 5.4 1.1e-30 106.8 5.4 1.1 1 0 0 1 1 1 1 RTA1 like protein UNC-50 PF05216.13 EGD86444.2 - 0.058 13.0 2.7 0.11 12.1 0.1 2.0 1 1 1 2 2 2 0 UNC-50 family DHHC PF01529.20 EGD86444.2 - 0.059 13.5 1.2 0.15 12.2 0.5 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase adh_short PF00106.25 EGD86447.1 - 9.5e-35 119.8 0.1 1.2e-34 119.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD86447.1 - 2.2e-32 112.5 0.1 2.7e-32 112.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD86447.1 - 5.2e-12 46.0 0.2 7.5e-12 45.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGD86447.1 - 4.2e-05 23.1 0.3 0.00097 18.7 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGD86447.1 - 0.0038 16.4 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 EGD86447.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyco_hydro_18 PF00704.28 EGD86448.1 - 1.9e-19 70.6 0.5 6.6e-19 68.8 0.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 AAA_22 PF13401.6 EGD86449.2 - 0.0058 16.9 0.1 2.3 8.5 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 EGD86449.2 - 0.022 15.2 0.0 0.08 13.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EGD86449.2 - 0.098 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EGD86449.2 - 0.16 11.3 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.7 EGD86449.2 - 0.18 10.7 0.1 1.9 7.4 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain SUR7 PF06687.12 EGD86450.1 - 1.5e-24 86.8 6.6 2.1e-24 86.3 6.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family O-antigen_lig PF13425.6 EGD86450.1 - 0.29 9.9 0.0 4.3 6.0 0.0 2.0 2 0 0 2 2 2 0 O-antigen ligase like membrane protein SNARE PF05739.19 EGD86451.1 - 9.5e-13 47.9 0.1 2.5e-12 46.6 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 EGD86451.1 - 4e-11 41.8 0.2 1.1e-10 40.5 0.2 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 EGD86451.1 - 0.00051 20.3 2.9 1.2 9.5 0.1 3.6 4 0 0 4 4 4 2 Uncharacterized conserved protein Syntaxin PF00804.25 EGD86451.1 - 0.0012 18.5 2.9 0.0097 15.6 0.1 2.8 2 1 0 2 2 2 1 Syntaxin NPV_P10 PF05531.12 EGD86451.1 - 0.029 14.9 1.5 8.1 7.0 0.1 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.21 EGD86451.1 - 0.047 13.5 4.8 0.35 10.7 0.4 2.7 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4988 PF16378.5 EGD86451.1 - 0.052 13.2 1.1 13 5.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function Syntaxin-18_N PF10496.9 EGD86451.1 - 0.1 12.8 2.5 0.16 12.2 0.1 2.5 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus AATF-Che1 PF13339.6 EGD86451.1 - 0.53 11.0 3.9 0.78 10.4 0.5 2.6 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor AMP-binding PF00501.28 EGD86453.1 - 3.7e-155 516.7 0.0 1.1e-70 238.4 0.0 3.8 4 0 0 4 4 4 3 AMP-binding enzyme Condensation PF00668.20 EGD86453.1 - 1.7e-98 330.3 0.0 4.3e-30 104.8 0.0 5.5 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.25 EGD86453.1 - 4.8e-26 90.9 0.1 6.2e-14 52.1 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGD86453.1 - 0.00064 20.6 0.0 0.013 16.5 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain IncF PF17626.2 EGD86453.1 - 0.077 13.4 0.5 12 6.3 0.0 3.0 2 0 0 2 2 2 0 Inclusion membrane protein F Amidase PF01425.21 EGD86454.2 - 9.8e-37 127.0 0.8 1.4e-36 126.5 0.2 1.4 2 0 0 2 2 2 1 Amidase Amino_oxidase PF01593.24 EGD86455.2 - 3.7e-22 79.2 0.1 4.3e-22 79.0 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase ARL2_Bind_BART PF11527.8 EGD86455.2 - 0.045 13.9 0.2 0.099 12.7 0.2 1.5 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Abhydrolase_4 PF08386.10 EGD86456.1 - 1.1e-19 70.4 0.0 3.2e-19 68.9 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 EGD86456.1 - 4.1e-12 46.3 0.0 5.9e-11 42.5 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Beta-lactamase PF00144.24 EGD86457.2 - 3e-16 59.6 0.0 3.8e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Ank_4 PF13637.6 EGD86458.2 - 5.5e-06 26.8 0.0 8.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGD86458.2 - 3.3e-05 24.4 0.0 4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGD86458.2 - 0.00097 19.4 0.0 0.011 16.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EGD86458.2 - 0.0024 18.1 0.0 0.0055 17.0 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGD86458.2 - 0.0049 17.3 0.0 0.34 11.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Glyco_hydro_16 PF00722.21 EGD86460.1 - 7.2e-18 64.7 0.0 4.7e-17 62.0 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 EGD86461.2 - 1.6e-54 184.9 0.8 1.6e-54 184.9 0.8 2.9 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGD86461.2 - 0.019 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 WSC PF01822.19 EGD86462.1 - 1.9e-36 124.1 31.3 4.4e-18 65.2 12.1 2.6 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.23 EGD86462.1 - 1.7e-21 77.0 0.3 3.3e-21 76.1 0.3 1.4 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.18 EGD86462.1 - 0.025 14.6 0.0 0.083 12.9 0.0 1.9 1 0 0 1 1 1 0 Photosystem I psaG / psaK Pterin_4a PF01329.19 EGD86463.1 - 5.1e-20 71.4 0.0 6.3e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase AbiEi_4 PF13338.6 EGD86463.1 - 0.099 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin TrmB PF01978.19 EGD86463.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB ABC_tran PF00005.27 EGD86466.2 - 2e-46 157.9 0.1 2.6e-34 118.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGD86466.2 - 7.5e-46 157.0 17.6 1e-45 156.5 17.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGD86466.2 - 6.1e-15 55.2 0.6 2.7e-06 27.0 0.2 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 EGD86466.2 - 0.00045 20.6 0.7 0.27 11.6 0.1 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 EGD86466.2 - 0.00047 20.3 1.4 0.52 10.6 0.3 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EGD86466.2 - 0.0011 18.9 0.1 0.013 15.3 0.0 2.4 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGD86466.2 - 0.0011 19.4 0.7 0.0041 17.5 0.1 2.4 3 1 0 3 3 2 1 AAA ATPase domain AAA_30 PF13604.6 EGD86466.2 - 0.0011 18.7 0.1 0.017 14.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGD86466.2 - 0.0014 18.9 2.2 0.014 15.6 0.1 3.3 3 1 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 EGD86466.2 - 0.0027 16.6 0.1 0.021 13.7 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class Rad17 PF03215.15 EGD86466.2 - 0.0052 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGD86466.2 - 0.03 14.2 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF2057 PF09829.9 EGD86466.2 - 0.041 14.0 0.3 7 6.8 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2057) AAA_15 PF13175.6 EGD86466.2 - 0.042 13.6 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 EGD86466.2 - 0.063 13.0 0.2 2.1 8.0 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EGD86466.2 - 0.1 11.9 0.0 0.28 10.4 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Dala_Dala_lig_N PF01820.21 EGD86466.2 - 0.15 12.5 0.0 3.8 8.0 0.0 2.7 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus DUF592 PF04574.13 EGD86466.2 - 0.23 11.2 0.5 3.3 7.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF592) NAD_binding_2 PF03446.15 EGD86467.1 - 3e-35 121.7 0.0 4.6e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGD86467.1 - 6.6e-27 94.2 0.0 1e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EGD86467.1 - 6.8e-07 29.8 0.0 2.1e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGD86467.1 - 0.0002 20.8 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EGD86467.1 - 0.0016 19.3 0.0 0.0032 18.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MMS1_N PF10433.9 EGD86468.2 - 2.1e-85 287.2 0.4 3.7e-85 286.4 0.4 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGD86468.2 - 4.1e-14 52.6 0.0 4.8e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region PQQ_2 PF13360.6 EGD86468.2 - 0.0025 17.4 0.1 0.18 11.3 0.0 2.5 2 0 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 EGD86468.2 - 0.0033 17.8 2.5 2.7 8.6 0.1 4.7 6 0 0 6 6 6 1 PQQ-like domain CENP-S PF15630.6 EGD86469.1 - 3.9e-30 104.0 0.0 5.1e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGD86469.1 - 1.3e-10 41.3 0.0 1.5e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EGD86469.1 - 0.04 13.9 0.0 0.082 12.9 0.0 1.6 1 1 0 1 1 1 0 Bromodomain associated PGA2 PF07543.12 EGD86470.1 - 3.6e-43 146.8 0.7 4.2e-43 146.7 0.7 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 CCD PF07860.11 EGD86470.1 - 0.024 14.7 0.2 0.12 12.5 0.0 2.0 1 1 1 2 2 2 0 WisP family C-Terminal Region MARVEL PF01284.23 EGD86471.2 - 0.00012 22.2 8.9 0.00015 21.8 8.9 1.3 1 1 0 1 1 1 1 Membrane-associating domain Phage_r1t_holin PF16945.5 EGD86471.2 - 0.089 13.0 0.1 0.26 11.5 0.1 1.8 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin Glyco_hydro_61 PF03443.14 EGD86472.2 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DUF2235 PF09994.9 EGD86473.1 - 1.4e-99 333.1 0.1 1.8e-99 332.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.15 EGD86474.2 - 5.4e-41 140.8 0.0 3.5e-23 82.0 0.0 3.2 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 EGD86474.2 - 2.8e-08 32.9 0.0 1e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Hexapep PF00132.24 EGD86475.1 - 3e-07 29.9 12.1 1.5e-05 24.5 4.1 4.4 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGD86475.1 - 0.0002 21.0 8.2 0.0015 18.2 0.6 2.7 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EGD86475.1 - 0.069 12.1 0.0 0.094 11.6 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase Arrestin_C PF02752.22 EGD86476.1 - 2.8e-18 66.6 0.0 5.5e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGD86476.1 - 1.4e-09 38.1 0.0 2.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Glyoxalase PF00903.25 EGD86477.2 - 3.8e-18 65.9 0.1 5.1e-18 65.5 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGD86477.2 - 1.7e-08 34.7 0.0 4.9e-06 26.8 0.0 2.6 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGD86477.2 - 0.11 12.6 0.0 0.49 10.5 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase PF00903.25 EGD86479.1 - 1.7e-36 125.3 0.1 2.7e-17 63.1 0.1 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGD86479.1 - 8.3e-20 71.1 0.0 3e-06 27.5 0.0 4.0 1 1 3 4 4 4 4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EGD86479.1 - 4.9e-07 30.5 0.0 0.0023 18.7 0.0 3.2 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EGD86479.1 - 1.1e-06 28.9 0.0 0.013 15.6 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EGD86479.1 - 0.022 14.7 0.1 4.7 7.2 0.0 3.6 4 0 0 4 4 4 0 Glyoxalase-like domain CppA_N PF14506.6 EGD86479.1 - 0.037 14.1 0.0 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 CppA N-terminal Kin17_mid PF10357.9 EGD86480.1 - 8.1e-48 161.5 1.6 1.6e-47 160.5 1.6 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 EGD86480.1 - 2.3e-05 24.6 0.9 5.5e-05 23.4 0.9 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGD86480.1 - 0.00046 20.4 0.3 0.00046 20.4 0.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGD86480.1 - 0.0082 16.5 2.9 0.013 15.8 0.4 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Hydin_ADK PF17213.3 EGD86480.1 - 2.2 8.5 6.3 0.92 9.7 3.9 1.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Ig_GlcNase PF18368.1 EGD86481.1 - 6.4e-36 122.7 0.1 4.7e-35 119.9 0.0 2.4 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 EGD86481.1 - 9.6e-12 45.6 0.2 5.6e-11 43.1 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EGD86481.1 - 1e-06 28.8 0.0 2.5e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Mannosidase_ig PF17786.1 EGD86481.1 - 8.9e-06 26.2 0.1 0.00048 20.7 0.0 2.5 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ank_2 PF12796.7 EGD86482.1 - 4e-72 238.8 11.4 8.6e-14 51.9 0.3 7.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD86482.1 - 2e-60 200.4 15.7 2.8e-11 43.7 0.4 8.8 4 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD86482.1 - 2.7e-52 168.6 11.1 2.8e-05 24.2 0.0 12.1 12 0 0 12 12 12 10 Ankyrin repeat Ank PF00023.30 EGD86482.1 - 8.7e-47 155.6 14.6 6.6e-06 26.3 0.0 11.9 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 EGD86482.1 - 3e-44 148.5 17.0 7.3e-08 32.5 0.0 9.8 4 2 5 10 10 10 9 Ankyrin repeats (many copies) Fe-ADH PF00465.19 EGD86483.1 - 4.5e-103 344.9 0.0 5.9e-103 344.5 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGD86483.1 - 3.1e-16 59.9 0.0 5.1e-12 46.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 EGD86483.1 - 0.015 14.9 0.1 0.025 14.2 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding protein 2-Hacid_dh_C PF02826.19 EGD86484.2 - 5.8e-39 133.3 0.0 9.6e-39 132.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGD86484.2 - 0.0014 18.3 0.1 0.0025 17.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 EGD86484.2 - 0.0099 15.6 0.3 0.084 12.7 0.0 2.5 3 0 0 3 3 3 1 ACT domain p450 PF00067.22 EGD86486.1 - 9.3e-60 202.7 0.0 3.5e-43 148.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_20 PF00728.22 EGD86487.1 - 4e-74 250.1 0.0 6.7e-74 249.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGD86487.1 - 9.8e-34 116.9 0.1 2.1e-33 115.9 0.1 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGD86487.1 - 0.00041 21.1 0.0 0.0044 17.8 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolase family 20, domain 2 zf-CCCH_2 PF14608.6 EGD86488.2 - 1.5e-12 47.5 51.8 9e-07 29.1 10.1 5.5 5 1 0 5 5 5 4 RNA-binding, Nab2-type zinc finger TFIIA PF03153.13 EGD86488.2 - 2.6 7.9 7.8 3.1 7.7 7.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PyrI_C PF02748.15 EGD86488.2 - 5.6 7.0 12.4 3.9 7.5 0.3 3.6 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Amino_oxidase PF01593.24 EGD86489.1 - 4.9e-31 108.5 0.0 5.8e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGD86489.1 - 2.3e-14 53.4 0.1 7.4e-14 51.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGD86489.1 - 3.4e-09 36.8 0.0 6.4e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGD86489.1 - 7e-05 22.2 0.0 0.0007 18.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGD86489.1 - 0.00086 18.8 0.2 0.0013 18.1 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGD86489.1 - 0.0012 18.2 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EGD86489.1 - 0.0013 18.8 0.0 0.006 16.6 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EGD86489.1 - 0.0021 16.8 0.0 0.0079 14.9 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EGD86489.1 - 0.0078 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EGD86489.1 - 0.013 16.0 0.0 0.8 10.3 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGD86489.1 - 0.027 13.6 0.0 0.41 9.7 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EGD86489.1 - 0.086 11.9 0.0 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FMO-like PF00743.19 EGD86489.1 - 0.12 10.8 0.3 0.23 9.8 0.0 1.5 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like MCRA PF06100.11 EGD86489.1 - 0.24 10.1 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 MCRA family Mago-bind PF09282.10 EGD86490.1 - 3.2e-14 52.5 2.6 5.8e-14 51.6 2.6 1.5 1 0 0 1 1 1 1 Mago binding MSA_2 PF00985.17 EGD86490.1 - 0.098 13.0 10.1 0.15 12.4 10.1 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family DUF4407 PF14362.6 EGD86490.1 - 0.72 9.2 6.2 0.77 9.1 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PVL_ORF50 PF07768.11 EGD86490.1 - 3.8 7.8 9.8 9.5 6.6 9.6 1.8 1 1 1 2 2 2 0 PVL ORF-50-like family Presenilin PF01080.17 EGD86490.1 - 5.7 5.6 7.1 6.5 5.4 7.1 1.1 1 0 0 1 1 1 0 Presenilin UCR_UQCRX_QCR9 PF05365.12 EGD86491.1 - 2.3e-27 94.7 1.4 2.6e-27 94.5 1.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4203 PF13886.6 EGD86491.1 - 0.069 12.8 0.0 0.069 12.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) zf-UBR PF02207.20 EGD86492.1 - 6.9e-16 58.2 19.4 6.9e-16 58.2 19.4 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EGD86492.1 - 6.3e-05 22.7 0.0 0.0002 21.1 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 EGD86492.1 - 0.016 15.5 1.0 0.016 15.5 1.0 4.1 3 0 0 3 3 3 0 Ring finger domain ELL PF10390.9 EGD86492.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL TPR_12 PF13424.6 EGD86493.2 - 4.7e-10 39.6 3.5 7.5e-05 22.9 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGD86493.2 - 7.9e-09 35.9 0.0 0.18 12.3 0.0 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGD86493.2 - 5.2e-06 26.0 0.0 0.1 12.4 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGD86493.2 - 5.3e-06 26.1 0.3 0.2 11.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGD86493.2 - 6.7e-06 25.7 1.5 0.0099 15.3 0.0 2.3 1 1 0 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 EGD86493.2 - 2.1e-05 24.2 0.4 7.4 6.8 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGD86493.2 - 0.00067 19.4 1.6 1.2 9.1 0.2 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGD86493.2 - 0.0036 17.8 8.1 9.3 7.2 0.2 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGD86493.2 - 0.11 13.4 6.3 63 4.8 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Cortex-I_coil PF09304.10 EGD86493.2 - 0.14 12.4 0.3 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil Fungal_trans PF04082.18 EGD86494.1 - 5.7e-11 42.0 1.3 9.7e-11 41.2 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD86494.1 - 2.3e-09 37.2 9.5 4.7e-09 36.2 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 EGD86496.1 - 6.5e-21 74.3 1.8 1.3e-20 73.3 1.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGD86496.1 - 5.7e-07 29.6 0.0 1.2e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF3237 PF11578.8 EGD86497.2 - 2.3e-10 40.5 0.0 2.7e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Hexokinase_1 PF00349.21 EGD86498.2 - 3.6e-58 196.7 0.0 4.9e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EGD86498.2 - 3.6e-45 154.3 0.0 5.2e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF4379 PF14311.6 EGD86499.1 - 0.014 15.7 0.8 0.014 15.7 0.8 1.8 2 0 0 2 2 2 0 Probable Zinc-ribbon domain BNIP2 PF12496.8 EGD86499.1 - 0.32 11.4 6.5 0.58 10.6 6.5 1.4 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Mad3_BUB1_I PF08311.12 EGD86500.1 - 2.7e-44 150.1 0.1 6.1e-44 149.0 0.1 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 EGD86500.1 - 4.5e-16 58.8 0.0 3.3e-15 56.0 0.0 2.4 2 1 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 EGD86500.1 - 1.8e-12 47.2 0.0 3.1e-11 43.1 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD86500.1 - 0.00052 19.4 0.0 0.0019 17.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 EGD86500.1 - 0.0032 17.6 0.0 0.0077 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein APH PF01636.23 EGD86500.1 - 0.023 14.6 0.2 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family AP_endonuc_2 PF01261.24 EGD86501.2 - 3.6e-10 39.6 0.0 5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SPT2 PF08243.11 EGD86501.2 - 0.0071 16.9 4.9 0.012 16.1 4.9 1.3 1 0 0 1 1 1 1 SPT2 chromatin protein HET PF06985.11 EGD86502.1 - 6.1e-27 94.8 1.1 2.4e-22 79.8 0.6 2.6 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 EGD86502.1 - 2.5e-14 53.6 0.0 3e-07 30.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD86502.1 - 7.6e-08 32.8 0.0 0.00041 20.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGD86502.1 - 6.7e-07 29.5 0.1 1.4e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGD86502.1 - 5.4e-05 23.5 0.0 0.8 10.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGD86502.1 - 0.0001 22.4 0.0 0.15 12.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat AA_permease PF00324.21 EGD86503.1 - 3.1e-113 378.9 35.8 3.8e-113 378.6 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD86503.1 - 3.2e-28 98.7 38.4 3.8e-28 98.5 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_C15 PF01470.17 EGD86507.1 - 9.6e-13 48.8 0.0 4e-06 27.1 0.0 2.5 2 1 0 2 2 2 2 Pyroglutamyl peptidase 6PGD PF00393.19 EGD86508.1 - 1.1e-127 425.4 0.0 1.4e-127 425.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGD86508.1 - 2.8e-50 170.6 0.0 4.1e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EGD86508.1 - 0.053 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 EGD86508.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Esterase_phd PF10503.9 EGD86508.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase RRM_1 PF00076.22 EGD86509.2 - 4.6e-18 64.8 0.0 7.8e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 EGD86509.2 - 3.2 7.7 23.6 4.9 7.1 23.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AD PF09793.9 EGD86510.1 - 1.6e-25 89.1 0.0 3.7e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain TPT PF03151.16 EGD86511.1 - 6e-23 81.6 18.3 7.8e-23 81.2 18.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGD86511.1 - 1.5e-06 28.4 38.8 8.5e-05 22.7 17.0 2.4 2 1 0 2 2 2 2 EamA-like transporter family DNA_pol_phi PF04931.13 EGD86512.2 - 1.6e-112 377.1 4.0 2e-112 376.8 4.0 1.0 1 0 0 1 1 1 1 DNA polymerase phi VHS PF00790.19 EGD86512.2 - 0.046 13.6 0.5 3 7.7 0.1 2.7 2 1 0 2 2 2 0 VHS domain Iso_dh PF00180.20 EGD86513.1 - 1.1e-90 304.3 0.0 1.2e-90 304.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Rhodanese PF00581.20 EGD86516.1 - 1e-13 51.8 0.1 1.9e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 Rhodanese-like domain SLD5_C PF16922.5 EGD86517.1 - 2.6e-10 40.3 0.3 4.5e-10 39.6 0.3 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EGD86517.1 - 1.5e-08 35.0 1.5 2.2e-08 34.5 1.5 1.2 1 0 0 1 1 1 1 GINS complex protein DUF4899 PF16240.5 EGD86517.1 - 0.032 13.4 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) Cullin PF00888.22 EGD86518.2 - 5e-200 666.2 6.0 5e-200 666.2 6.0 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EGD86518.2 - 5.6e-28 96.8 1.1 6.7e-27 93.3 0.8 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain DUF1737 PF08410.10 EGD86518.2 - 0.18 11.7 0.1 0.5 10.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) HEPN_DZIP3 PF18738.1 EGD86518.2 - 0.2 11.4 1.4 19 5.0 0.1 2.9 2 1 0 2 2 2 0 DZIP3/ hRUL138-like HEPN Kinesin_assoc PF16183.5 EGD86518.2 - 3.1 7.9 6.1 5.2 7.2 0.1 3.0 3 0 0 3 3 3 0 Kinesin-associated zf-DNL PF05180.12 EGD86519.1 - 1.3e-27 95.4 0.4 2.3e-27 94.7 0.4 1.4 1 0 0 1 1 1 1 DNL zinc finger TFIIS_C PF01096.18 EGD86519.1 - 0.0094 15.8 1.1 1.4 8.8 0.2 2.4 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) zf-CSL PF05207.13 EGD86519.1 - 0.017 14.8 0.1 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 CSL zinc finger Elf1 PF05129.13 EGD86519.1 - 0.076 13.1 0.3 0.14 12.3 0.3 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like MMtag PF10159.9 EGD86519.1 - 0.23 11.8 0.2 0.23 11.8 0.2 1.7 2 0 0 2 2 2 0 Multiple myeloma tumor-associated zinc_ribbon_4 PF13717.6 EGD86519.1 - 0.23 11.4 2.1 0.52 10.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain E7 PF00527.18 EGD86519.1 - 0.35 11.1 3.6 0.7 10.1 1.8 2.4 2 1 0 2 2 2 0 E7 protein, Early protein DRIM PF07539.12 EGD86520.1 - 1.6e-187 624.6 14.2 5e-187 623.0 0.3 4.2 5 0 0 5 5 5 2 Down-regulated in metastasis HEAT PF02985.22 EGD86520.1 - 0.0021 18.1 6.1 0.67 10.4 0.0 6.5 7 0 0 7 7 7 1 HEAT repeat Wap1 PF16997.5 EGD86520.1 - 0.011 14.9 0.0 3.2 6.8 0.0 3.6 3 0 0 3 3 3 0 Wap1 domain CwfJ_C_1 PF04677.15 EGD86521.1 - 9.2e-25 86.9 0.0 1.5e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EGD86521.1 - 1.2e-15 58.2 0.2 2.6e-15 57.1 0.2 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF4831 PF16115.5 EGD86522.2 - 0.13 11.3 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4831) MFS_1 PF07690.16 EGD86523.2 - 2.2e-14 53.2 45.3 1.2e-13 50.8 38.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGD86523.2 - 2.9e-06 26.9 21.6 3.6e-06 26.5 21.6 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF5516 PF17637.2 EGD86523.2 - 9 6.1 8.0 23 4.8 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5516) Corona_S2 PF01601.16 EGD86524.1 - 1.3 7.4 16.9 1.7 7.0 16.9 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein RCR PF12273.8 EGD86525.1 - 1.3e-15 58.1 16.5 1.3e-15 58.1 16.5 1.9 2 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red BAT2_N PF07001.11 EGD86525.1 - 0.0038 17.7 3.7 0.0047 17.4 3.7 1.1 1 0 0 1 1 1 1 BAT2 N-terminus DUF2868 PF11067.8 EGD86525.1 - 0.0063 16.1 0.6 0.0067 16.0 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2868) CYYR1 PF10873.8 EGD86525.1 - 0.0071 16.8 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 TMEM51 PF15345.6 EGD86525.1 - 0.015 15.1 0.9 0.026 14.4 0.9 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 SARAF PF06682.12 EGD86525.1 - 0.04 13.6 8.0 0.063 12.9 8.0 1.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 EGD86525.1 - 0.15 13.1 0.0 0.24 12.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Arf PF00025.21 EGD86526.1 - 1.6e-43 148.1 0.0 1.9e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGD86526.1 - 5.5e-20 71.6 0.0 6.2e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD86526.1 - 3.5e-15 56.3 0.0 5.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGD86526.1 - 2.9e-08 33.8 0.0 4.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGD86526.1 - 1.9e-06 27.5 0.0 2.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGD86526.1 - 2.4e-06 27.1 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGD86526.1 - 7.2e-05 22.1 0.0 0.00058 19.1 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 EGD86526.1 - 0.00064 19.7 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 EGD86526.1 - 0.0024 17.9 0.1 0.035 14.2 0.2 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 EGD86526.1 - 0.022 14.3 0.2 0.061 12.9 0.0 1.7 3 0 0 3 3 3 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGD86526.1 - 0.081 12.8 0.1 9 6.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF1979 PF09322.10 EGD86526.1 - 0.17 11.8 1.6 3.5 7.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) PS-DH PF14765.6 EGD86527.2 - 7.8e-61 205.9 0.0 1.2e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 EGD86527.2 - 1.5e-60 205.0 0.0 2.9e-60 204.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGD86527.2 - 5.6e-57 193.6 0.0 3.5e-56 191.0 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGD86527.2 - 6.9e-27 93.8 0.0 1.7e-26 92.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGD86527.2 - 1.8e-22 79.9 0.0 4.7e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EGD86527.2 - 1.1e-17 64.6 0.0 2.2e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD86527.2 - 5.1e-15 55.7 0.0 1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD86527.2 - 4.1e-11 42.9 0.0 8.9e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD86527.2 - 5.3e-10 39.8 0.0 1.6e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD86527.2 - 1.5e-09 38.4 0.0 3.8e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGD86527.2 - 4e-06 26.7 0.0 9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 EGD86527.2 - 3.6e-05 23.2 0.0 0.0001 21.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 EGD86527.2 - 0.00053 19.9 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NodS PF05401.11 EGD86527.2 - 0.0034 17.0 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Rsm22 PF09243.10 EGD86527.2 - 0.0098 15.2 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 DREV PF05219.12 EGD86527.2 - 0.024 13.7 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_24 PF13578.6 EGD86527.2 - 0.034 15.1 0.0 0.12 13.4 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain RNA_pol_Rpb2_6 PF00562.28 EGD86528.1 - 2.9e-116 388.8 0.0 3.8e-116 388.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGD86528.1 - 1.9e-38 132.0 0.0 3e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EGD86528.1 - 1.5e-27 95.5 0.0 3.1e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EGD86528.1 - 1.3e-26 93.4 0.0 2.5e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EGD86528.1 - 1.5e-25 89.0 0.0 3.4e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 EGD86528.1 - 6.3e-16 58.5 0.0 1.4e-14 54.2 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 SWI-SNF_Ssr4 PF08549.10 EGD86529.1 - 2.4e-247 823.2 12.8 8.1e-247 821.5 12.8 1.7 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) DUF4832 PF16116.5 EGD86529.1 - 0.16 11.8 0.2 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4832) Pil1 PF13805.6 EGD86531.1 - 3.7e-84 282.3 1.6 4.3e-84 282.1 1.6 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 Proteasome PF00227.26 EGD86532.1 - 1.2e-46 158.6 0.1 1.5e-46 158.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Ppx-GppA PF02541.16 EGD86533.1 - 1.5e-40 139.4 0.0 1.6e-39 136.1 0.0 2.0 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Thi4 PF01946.17 EGD86535.1 - 3.3e-108 360.3 0.0 4e-108 360.1 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EGD86535.1 - 6.4e-07 29.3 0.0 7.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGD86535.1 - 1.4e-05 25.2 0.1 7.9e-05 22.8 0.1 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGD86535.1 - 0.00019 20.6 0.3 0.00034 19.8 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EGD86535.1 - 0.0018 17.6 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGD86535.1 - 0.0036 17.3 0.2 0.015 15.3 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EGD86535.1 - 0.078 11.8 0.2 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 EGD86535.1 - 0.088 12.0 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 EGD86535.1 - 0.12 11.4 0.3 0.3 10.1 0.3 1.6 2 0 0 2 2 2 0 FAD binding domain Exo_endo_phos PF03372.23 EGD86536.1 - 1.2e-13 51.1 0.1 1.8e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 EGD86537.1 - 1.1e-57 190.6 11.0 7.8e-11 42.4 0.6 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD86537.1 - 3.6e-24 84.9 0.0 0.00017 21.8 0.0 6.0 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD86537.1 - 1.9e-08 33.4 0.5 0.055 12.1 0.0 4.6 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGD86537.1 - 3e-08 33.0 0.2 0.042 12.8 0.0 4.6 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGD86537.1 - 1.3e-05 24.7 0.0 0.0002 20.8 0.0 2.7 2 1 1 3 3 3 1 WD40-like domain Nbas_N PF15492.6 EGD86537.1 - 0.0035 16.7 0.2 3.6 6.8 0.0 3.1 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EGD86537.1 - 0.0035 17.2 8.2 0.9 9.6 0.1 5.2 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 EGD86537.1 - 0.0071 15.5 0.1 0.29 10.2 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF1513) Frtz PF11768.8 EGD86537.1 - 0.039 12.3 0.0 0.14 10.5 0.0 1.8 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 EGD86537.1 - 0.081 11.8 0.0 11 4.8 0.0 3.2 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain UNC-93 PF05978.16 EGD86538.1 - 1.7e-05 24.6 2.3 1.7e-05 24.6 2.3 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 CcmE PF03100.15 EGD86538.1 - 0.056 13.4 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 CcmE KGG PF10685.9 EGD86540.2 - 1.3e-24 85.7 15.7 8.7e-10 38.6 0.5 3.3 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif HTH_23 PF13384.6 EGD86541.1 - 9.7e-07 28.4 0.2 2.6e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 EGD86541.1 - 5.3e-05 22.9 0.6 5.3e-05 22.9 0.6 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EGD86541.1 - 5.9e-05 22.7 0.1 0.00062 19.4 0.1 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_32 PF13565.6 EGD86541.1 - 9.9e-05 22.9 3.1 0.0043 17.6 0.1 2.8 2 1 1 3 3 3 1 Homeodomain-like domain Mucin PF01456.17 EGD86541.1 - 0.00061 19.8 4.9 0.00084 19.4 4.9 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein HTH_7 PF02796.15 EGD86541.1 - 0.0011 19.0 0.3 0.25 11.5 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_31 PF13560.6 EGD86541.1 - 0.0027 18.0 0.7 0.01 16.2 0.7 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 EGD86541.1 - 0.0062 16.6 1.8 0.0081 16.3 0.3 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain GerE PF00196.19 EGD86541.1 - 0.0065 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 EGD86541.1 - 0.028 13.9 0.1 0.11 12.0 0.1 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_1 PF01527.20 EGD86541.1 - 0.075 13.4 0.1 0.2 12.0 0.1 1.8 1 1 0 1 1 1 0 Transposase HTH_3 PF01381.22 EGD86541.1 - 0.15 12.1 1.6 0.19 11.8 0.2 1.9 3 0 0 3 3 3 0 Helix-turn-helix HTH_Tnp_Tc3_2 PF01498.18 EGD86541.1 - 0.22 11.8 2.0 0.42 10.9 0.0 2.3 3 0 0 3 3 3 0 Transposase DUF3439 PF11921.8 EGD86541.1 - 1.7 8.6 8.4 2.7 8.0 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AA_permease PF00324.21 EGD86542.2 - 3.7e-119 398.4 36.5 4.4e-119 398.2 36.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD86542.2 - 5.8e-29 101.2 41.2 7e-29 100.9 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.25 EGD86543.2 - 1.7e-14 53.7 0.1 2.3e-14 53.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD86543.2 - 1.5e-07 31.2 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_4 PF01565.23 EGD86544.2 - 1.2e-24 86.7 0.1 2e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGD86544.2 - 9.6e-05 22.4 0.3 0.00029 20.9 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like PsbT PF01405.17 EGD86544.2 - 0.046 13.5 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Patatin PF01734.22 EGD86546.2 - 0.044 13.9 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase Methyltransf_2 PF00891.18 EGD86546.2 - 0.12 11.7 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain DUF3328 PF11807.8 EGD86547.1 - 7.3e-14 52.1 0.2 9e-14 51.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_S8 PF00082.22 EGD86549.2 - 2.3e-16 59.9 2.3 3e-16 59.5 2.3 1.2 1 0 0 1 1 1 1 Subtilase family S8_pro-domain PF16470.5 EGD86549.2 - 0.022 15.5 0.0 0.083 13.7 0.0 2.0 2 0 0 2 2 2 0 Peptidase S8 pro-domain Glyco_hydro_cc PF11790.8 EGD86551.1 - 3.5e-61 206.8 1.1 4.1e-61 206.6 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RED_N PF07808.13 EGD86552.1 - 1.8e-08 34.3 6.5 1.8e-08 34.3 6.5 2.9 2 2 0 3 3 3 1 RED-like protein N-terminal region Cutinase PF01083.22 EGD86553.1 - 2e-35 122.3 0.0 2.4e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EGD86553.1 - 0.00024 20.7 0.0 0.00032 20.3 0.0 1.1 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 EGD86553.1 - 0.063 13.1 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) FSH1 PF03959.13 EGD86553.1 - 0.088 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) UPF0565 PF10561.9 EGD86553.1 - 0.1 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Abhydrolase_2 PF02230.16 EGD86553.1 - 0.2 11.4 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase LysM PF01476.20 EGD86555.1 - 7.1e-16 58.0 0.0 1.7e-07 31.2 0.0 3.2 3 0 0 3 3 3 3 LysM domain Cu-oxidase_3 PF07732.15 EGD86557.2 - 2.9e-43 146.7 0.3 5.1e-43 145.9 0.3 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 EGD86557.2 - 2e-33 115.8 0.1 5.3e-33 114.4 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGD86557.2 - 0.08 12.7 1.6 8.2 6.2 0.5 3.2 2 1 0 2 2 2 0 Multicopper oxidase DLH PF01738.18 EGD86558.1 - 5.1e-14 52.3 0.0 5.9e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF3237 PF11578.8 EGD86559.1 - 6.4e-07 29.3 0.1 9.4e-07 28.8 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) AA_permease_2 PF13520.6 EGD86561.1 - 4e-58 197.3 47.9 4.8e-58 197.0 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD86561.1 - 1.2e-20 73.6 39.1 1.6e-20 73.2 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease Plasmod_dom_1 PF09715.10 EGD86561.1 - 0.17 12.0 1.0 0.66 10.1 1.0 2.1 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) ketoacyl-synt PF00109.26 EGD86562.1 - 6.7e-67 225.7 0.0 1.5e-66 224.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EGD86562.1 - 6.4e-48 163.5 0.0 1.1e-47 162.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EGD86562.1 - 1.6e-47 161.8 0.0 3.2e-47 160.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EGD86562.1 - 4.6e-41 141.3 0.7 2.6e-40 138.9 0.1 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGD86562.1 - 2.7e-28 98.4 0.1 2.7e-28 98.4 0.1 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EGD86562.1 - 1.2e-19 70.9 0.0 4.3e-19 69.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGD86562.1 - 3.7e-15 56.4 0.0 9.1e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 EGD86562.1 - 8.5e-15 55.3 0.0 3.2e-14 53.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD86562.1 - 1.1e-12 48.4 0.0 3.1e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD86562.1 - 1.6e-10 41.1 0.0 3.5e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD86562.1 - 2.7e-09 37.0 0.0 8e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EGD86562.1 - 7.5e-08 32.0 0.0 1.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD86562.1 - 3.8e-06 26.6 0.0 8.3e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 EGD86562.1 - 4.3e-06 26.2 0.0 9.3e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 EGD86562.1 - 5.3e-05 23.5 0.2 0.00016 22.0 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGD86562.1 - 0.00026 20.5 0.8 0.00047 19.6 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_24 PF13578.6 EGD86562.1 - 0.0097 16.9 0.0 0.034 15.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGD86562.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase SAT PF16073.5 EGD86562.1 - 0.012 15.3 2.6 1.2 8.8 0.5 2.5 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis NodS PF05401.11 EGD86562.1 - 0.024 14.3 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.17 EGD86562.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Fungal_trans PF04082.18 EGD86563.2 - 1.9e-07 30.4 0.0 3.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EGD86564.2 - 1.5e-15 57.0 8.2 1.6e-15 56.9 8.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD86564.2 - 9.9e-09 34.6 5.0 1.1e-08 34.4 5.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Zn_clus PF00172.18 EGD86565.1 - 0.00048 20.2 9.0 0.00094 19.3 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC_2 PF13913.6 EGD86568.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 EGD86568.1 - 0.0072 17.1 0.3 0.017 15.9 0.3 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.12 EGD86568.1 - 0.013 15.7 0.1 0.028 14.7 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 EGD86568.1 - 0.058 13.9 0.4 0.12 12.8 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type JAKMIP_CC3 PF16034.5 EGD86568.1 - 0.072 13.0 3.2 0.17 11.8 3.2 1.6 1 0 0 1 1 1 0 JAKMIP CC3 domain 2OG-FeII_Oxy_2 PF13532.6 EGD86570.1 - 4.8e-30 105.2 0.0 6.7e-29 101.5 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 EGD86571.1 - 8e-70 235.2 0.0 1.1e-69 234.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD86571.1 - 3.9e-31 108.3 0.0 5.1e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD86571.1 - 0.00018 20.9 0.0 0.00041 19.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGD86571.1 - 0.00081 18.4 0.1 0.018 14.0 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGD86571.1 - 0.0025 17.8 0.1 0.0044 17.0 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGD86571.1 - 0.039 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Abhydrolase_3 PF07859.13 EGD86572.2 - 9.8e-06 25.6 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGD86572.2 - 0.0012 18.5 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EGD86572.2 - 0.0015 18.1 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family zf-C2H2_2 PF12756.7 EGD86574.2 - 2e-35 121.1 20.6 1.8e-30 105.2 3.3 3.9 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGD86574.2 - 1.6e-11 44.2 11.8 2.2e-05 24.6 2.4 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGD86574.2 - 1.9e-06 28.1 2.9 1.9e-06 28.1 2.9 3.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type DUF2024 PF09630.10 EGD86574.2 - 0.012 15.5 3.9 0.073 12.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) Inovirus_Gp2 PF11726.8 EGD86574.2 - 0.038 13.9 0.1 0.038 13.9 0.1 1.6 2 0 0 2 2 2 0 Inovirus Gp2 Cytochrome-c551 PF10643.9 EGD86574.2 - 0.094 12.3 0.3 11 5.6 0.0 2.2 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Cytochrome_CBB3 PF13442.6 EGD86574.2 - 0.1 12.9 3.2 7.2 7.0 0.3 3.0 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III zf-C2H2 PF00096.26 EGD86574.2 - 0.14 12.6 0.3 0.14 12.6 0.3 5.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type GOLD_2 PF13897.6 EGD86574.2 - 4.1 7.9 8.6 0.28 11.7 2.2 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking HECT PF00632.25 EGD86575.1 - 7.6e-68 229.2 0.0 4.2e-67 226.8 0.0 2.1 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EGD86575.1 - 1.9e-22 79.2 2.3 5.7e-22 77.7 2.3 1.9 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A His_Phos_1 PF00300.22 EGD86576.1 - 3.3e-15 56.3 0.0 6.4e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Transket_pyr PF02779.24 EGD86579.1 - 2.7e-42 144.5 0.0 4.3e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGD86579.1 - 1.5e-31 108.9 0.1 3.4e-31 107.7 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EGD86579.1 - 0.012 15.8 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II 3Beta_HSD PF01073.19 EGD86580.2 - 7.9e-53 179.3 0.0 9.9e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGD86580.2 - 5.7e-31 107.8 0.0 7.3e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGD86580.2 - 1.3e-18 67.5 0.1 4.8e-16 59.1 0.1 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGD86580.2 - 3.8e-10 39.4 0.3 1.4e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 EGD86580.2 - 1.2e-07 31.2 0.0 1.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGD86580.2 - 5e-06 26.5 0.0 6.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGD86580.2 - 1.5e-05 24.3 0.2 0.00011 21.5 0.1 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EGD86580.2 - 0.00011 22.1 0.8 0.002 18.1 0.8 2.3 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EGD86580.2 - 0.0054 16.2 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EGD86580.2 - 0.023 14.2 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.18 EGD86580.2 - 0.081 13.2 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain PglD_N PF17836.1 EGD86580.2 - 0.19 12.4 0.6 0.54 10.9 0.3 1.9 2 0 0 2 2 2 0 PglD N-terminal domain Zn_clus PF00172.18 EGD86584.2 - 4.6e-09 36.2 11.9 9.7e-09 35.2 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.10 EGD86584.2 - 1.4e-06 28.0 6.4 1.4e-06 28.0 6.4 2.1 1 1 1 2 2 2 1 Aflatoxin regulatory protein CTV_P13 PF06922.11 EGD86584.2 - 0.082 13.0 0.0 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Citrus tristeza virus P13 protein FAD_binding_4 PF01565.23 EGD86585.1 - 2.1e-15 56.7 1.5 3.9e-15 55.8 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGD86585.1 - 1.4e-06 28.2 0.1 4.6e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like Zn_clus PF00172.18 EGD86586.2 - 2.5e-08 33.9 12.7 4e-08 33.2 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cas_Cmr3 PF09700.10 EGD86586.2 - 0.0089 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cmr3) MFS_1 PF07690.16 EGD86587.1 - 1.1e-39 136.4 47.7 4.4e-39 134.4 47.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD86587.1 - 2.2e-07 30.1 39.7 1.2e-06 27.7 17.8 3.8 2 2 1 3 3 3 3 Sugar (and other) transporter DUF4407 PF14362.6 EGD86587.1 - 4.8 6.4 5.5 1.2 8.4 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Methyltransf_2 PF00891.18 EGD86588.1 - 2.2e-26 92.5 0.0 3.8e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 EGD86588.1 - 0.022 15.5 0.0 0.088 13.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGD86588.1 - 0.023 15.4 0.0 0.15 12.8 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain DUF938 PF06080.12 EGD86588.1 - 0.029 14.2 0.1 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF938) CheR PF01739.18 EGD86588.1 - 0.091 12.2 0.0 0.26 10.8 0.0 1.6 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Cu-oxidase_3 PF07732.15 EGD86589.1 - 2.9e-38 130.5 1.1 7.6e-38 129.2 0.3 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGD86589.1 - 1.3e-25 89.7 10.7 4.1e-21 75.1 0.3 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EGD86589.1 - 4.5e-18 65.9 0.0 1.3e-17 64.3 0.0 1.8 1 1 0 1 1 1 1 Multicopper oxidase Fasciclin PF02469.22 EGD86590.2 - 0.00013 22.2 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain HHV-1_VABD PF16852.5 EGD86590.2 - 0.0098 15.9 0.1 0.019 15.0 0.1 1.4 1 0 0 1 1 1 1 Herpes viral adaptor-to-host cellular mRNA binding domain T_cell_tran_alt PF15128.6 EGD86590.2 - 0.078 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 T-cell leukemia translocation-altered DUF5592 PF17332.2 EGD86590.2 - 0.086 13.4 0.1 0.23 12.0 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5592) adh_short PF00106.25 EGD86591.2 - 1.4e-28 99.7 0.7 4.7e-28 98.0 0.1 2.2 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD86591.2 - 2.3e-27 96.1 0.0 1.7e-26 93.2 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD86591.2 - 2.6e-05 24.2 0.1 5.5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 KR domain Fasciclin PF02469.22 EGD86591.2 - 0.028 14.6 0.4 0.061 13.5 0.4 1.5 1 0 0 1 1 1 0 Fasciclin domain Epimerase PF01370.21 EGD86591.2 - 0.077 12.4 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FMO-like PF00743.19 EGD86592.2 - 6.4e-60 203.1 0.0 7.8e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGD86592.2 - 6.9e-13 48.5 0.0 5.7e-10 38.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGD86592.2 - 5.1e-09 35.8 0.0 5.5e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGD86592.2 - 3.9e-07 29.5 0.2 1.4e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EGD86592.2 - 0.043 14.4 0.1 0.11 13.0 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cas_Csa5 PF09702.10 EGD86592.2 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) NAD_binding_9 PF13454.6 EGD86592.2 - 0.099 12.6 0.0 24 4.9 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding ketoacyl-synt PF00109.26 EGD86593.2 - 1.9e-79 266.8 0.0 3.3e-79 266.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGD86593.2 - 1.7e-35 123.1 0.0 2.6e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGD86593.2 - 6.1e-35 119.8 0.4 2.7e-34 117.7 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGD86593.2 - 3.7e-08 33.8 0.1 9.9e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension SAT PF16073.5 EGD86593.2 - 6.4e-05 22.8 0.4 0.0026 17.5 0.0 3.3 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 EGD86593.2 - 0.002 17.5 0.1 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain BMC PF00936.19 EGD86593.2 - 0.044 13.8 0.3 3.5 7.7 0.1 2.7 2 0 0 2 2 2 0 BMC domain Filament PF00038.21 EGD86595.1 - 0.046 13.3 0.6 0.072 12.7 0.6 1.2 1 0 0 1 1 1 0 Intermediate filament protein WD40 PF00400.32 EGD86596.1 - 3.3e-33 113.2 24.0 1.2e-09 38.6 0.2 8.5 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD86596.1 - 9.8e-09 35.4 0.7 0.016 15.5 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD86596.1 - 2.3e-06 26.6 3.2 0.05 12.2 0.1 4.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EGD86596.1 - 5.1e-06 25.6 0.7 3.4e-05 23.0 0.1 2.3 2 1 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 EGD86596.1 - 0.001 18.1 0.0 1.7 7.5 0.0 3.8 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 EGD86596.1 - 0.021 14.5 1.9 0.21 11.3 0.5 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split HPS3_N PF14761.6 EGD86596.1 - 0.19 11.3 0.0 0.92 9.0 0.0 2.1 1 1 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Tctex-1 PF03645.13 EGD86597.1 - 1.6e-35 121.4 0.0 2e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family MAT1-1-2 PF17043.5 EGD86597.1 - 0.1 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function Self-incomp_S1 PF05938.11 EGD86597.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 DUF202 PF02656.15 EGD86598.1 - 3.9e-14 52.8 4.5 3.9e-14 52.8 4.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 EGD86598.1 - 1.4 8.8 10.0 0.23 11.3 5.2 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5337) Metallophos_2 PF12850.7 EGD86600.1 - 3e-13 50.3 0.0 3.7e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L17 PF01196.19 EGD86601.1 - 3.2e-34 117.7 0.0 8.2e-34 116.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 Mrpl_C PF18502.1 EGD86601.1 - 0.093 13.0 0.1 1.1 9.6 0.0 2.0 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain AIM5 PF17050.5 EGD86602.1 - 4.9e-11 43.3 0.2 8.3e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 DUF5315 PF17242.2 EGD86603.1 - 5.3e-19 67.8 0.0 1.6e-18 66.3 0.0 1.9 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) THUMP PF02926.17 EGD86603.1 - 0.0092 16.1 0.9 0.014 15.5 0.9 1.2 1 0 0 1 1 1 1 THUMP domain Ribosom_S12_S23 PF00164.25 EGD86604.1 - 3.2e-50 168.5 1.0 4e-50 168.2 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 IF-2B PF01008.17 EGD86605.1 - 2.4e-59 200.9 6.4 2.3e-49 168.1 3.0 3.0 2 1 0 2 2 2 2 Initiation factor 2 subunit family Mob1_phocein PF03637.17 EGD86606.1 - 5e-52 176.3 0.0 1.1e-51 175.2 0.0 1.5 1 1 0 1 1 1 1 Mob1/phocein family Macoilin PF09726.9 EGD86606.1 - 5.8 5.4 4.6 7.2 5.0 4.6 1.1 1 0 0 1 1 1 0 Macoilin family Leo1 PF04004.13 EGD86607.1 - 4.8e-29 101.3 0.8 4.8e-29 101.3 0.8 2.4 2 1 0 2 2 2 1 Leo1-like protein EF-1_beta_acid PF10587.9 EGD86607.1 - 0.04 14.4 6.9 0.04 14.4 6.9 6.8 6 1 0 6 6 6 0 Eukaryotic elongation factor 1 beta central acidic region Zn_clus PF00172.18 EGD86608.1 - 2.8e-08 33.7 6.3 5.4e-08 32.8 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BOP1NT PF08145.12 EGD86609.1 - 2.8e-105 351.9 6.7 4.7e-105 351.2 6.7 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EGD86609.1 - 1.8e-20 72.9 7.1 1.1e-09 38.7 0.2 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD86609.1 - 7.4e-05 23.0 0.0 0.032 14.5 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGD86609.1 - 0.064 13.8 2.5 16 6.1 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain AAA PF00004.29 EGD86610.1 - 1.6e-91 303.6 0.0 1.6e-45 154.8 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD86610.1 - 6.7e-19 67.4 2.7 1.6e-09 37.4 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGD86610.1 - 5.7e-14 52.8 0.5 0.00014 22.3 0.1 4.6 2 2 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 EGD86610.1 - 3.2e-13 49.7 0.0 5.5e-06 26.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGD86610.1 - 2.4e-11 44.1 0.1 0.0062 16.8 0.0 5.1 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.6 EGD86610.1 - 5.2e-11 42.9 0.0 2.6e-05 24.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EGD86610.1 - 9.6e-11 42.1 0.0 0.00029 21.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGD86610.1 - 2.8e-10 40.3 0.1 0.0005 20.1 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGD86610.1 - 1.9e-09 37.2 0.1 0.00011 21.5 0.0 2.7 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_14 PF13173.6 EGD86610.1 - 5.5e-08 32.9 0.0 0.004 17.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGD86610.1 - 6.1e-08 33.0 0.0 0.0054 17.1 0.0 2.7 2 1 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 EGD86610.1 - 2.1e-07 31.6 0.0 0.01 16.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 EGD86610.1 - 4.8e-07 30.2 0.0 0.0073 16.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EGD86610.1 - 8.7e-07 28.8 0.1 0.067 12.9 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 EGD86610.1 - 1e-06 28.2 0.0 0.033 13.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.21 EGD86610.1 - 1.1e-06 28.3 2.6 0.023 14.1 0.1 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGD86610.1 - 1.3e-06 28.3 0.0 0.0042 16.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGD86610.1 - 8.7e-06 25.7 0.0 0.14 12.1 0.0 3.5 3 0 0 3 3 3 2 NACHT domain TsaE PF02367.17 EGD86610.1 - 1e-05 25.5 0.0 0.078 13.0 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EGD86610.1 - 1.6e-05 24.9 0.0 0.093 12.6 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 EGD86610.1 - 3.9e-05 23.2 0.0 0.13 11.7 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 EGD86610.1 - 4.9e-05 23.9 0.0 0.18 12.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.6 EGD86610.1 - 5.8e-05 22.8 0.5 1.2 8.7 0.0 4.0 3 1 1 4 4 4 2 AAA domain AAA_17 PF13207.6 EGD86610.1 - 6.5e-05 23.4 0.0 0.23 11.9 0.0 3.4 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 EGD86610.1 - 9.3e-05 21.9 0.1 0.66 9.3 0.0 3.1 2 1 0 3 3 3 2 KaiC Sigma54_activat PF00158.26 EGD86610.1 - 0.00011 21.9 0.0 0.38 10.4 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 EGD86610.1 - 0.00013 22.2 0.0 0.038 14.1 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family PhoH PF02562.16 EGD86610.1 - 0.00039 19.9 0.0 0.56 9.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein TniB PF05621.11 EGD86610.1 - 0.0004 19.9 0.0 0.13 11.6 0.0 3.1 3 0 0 3 3 3 1 Bacterial TniB protein AFG1_ATPase PF03969.16 EGD86610.1 - 0.00043 19.3 0.0 0.088 11.7 0.0 2.5 2 0 0 2 2 2 1 AFG1-like ATPase NB-ARC PF00931.22 EGD86610.1 - 0.00051 19.3 0.0 0.99 8.5 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain AAA_11 PF13086.6 EGD86610.1 - 0.00064 19.6 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain SKI PF01202.22 EGD86610.1 - 0.00071 19.7 0.0 0.78 9.8 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase ATPase_2 PF01637.18 EGD86610.1 - 0.00084 19.3 0.0 1.8 8.4 0.0 3.4 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGD86610.1 - 0.00096 18.9 0.0 0.88 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 EGD86610.1 - 0.00096 19.3 0.0 2.4 8.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.13 EGD86610.1 - 0.0011 18.1 0.0 0.051 12.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 EGD86610.1 - 0.0017 18.1 0.0 0.89 9.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 EGD86610.1 - 0.002 17.2 0.0 1.7 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 EGD86610.1 - 0.012 15.9 1.4 4.7 7.5 0.3 3.0 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 EGD86610.1 - 0.018 14.9 0.0 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 EGD86610.1 - 0.025 14.6 0.0 8.8 6.3 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EGD86610.1 - 0.032 14.7 0.5 5.1 7.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain Vps4_C PF09336.10 EGD86610.1 - 0.044 13.8 0.2 2.6 8.1 0.0 3.0 2 1 0 2 2 2 0 Vps4 C terminal oligomerisation domain DUF2075 PF09848.9 EGD86610.1 - 0.084 12.1 0.0 5.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IPT PF01745.16 EGD86610.1 - 0.089 12.2 0.2 11 5.3 0.0 2.6 3 0 0 3 3 2 0 Isopentenyl transferase NTPase_1 PF03266.15 EGD86610.1 - 0.11 12.4 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 NTPase SRPRB PF09439.10 EGD86610.1 - 0.12 11.8 0.0 15 5.0 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_30 PF13604.6 EGD86610.1 - 0.14 11.9 0.4 18 5.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain Cytidylate_kin PF02224.18 EGD86610.1 - 0.16 11.7 0.1 13 5.4 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Snf7 PF03357.21 EGD86611.1 - 4.2e-30 104.6 9.6 5.2e-30 104.3 9.6 1.1 1 0 0 1 1 1 1 Snf7 DHDPS PF00701.22 EGD86611.1 - 0.009 14.8 0.3 0.017 13.9 0.2 1.4 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family HSCB_C PF07743.13 EGD86611.1 - 0.94 10.0 10.4 1.7 9.2 3.3 2.7 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain PITH PF06201.13 EGD86612.1 - 9.4e-43 146.0 0.0 1.1e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 PITH domain HA2 PF04408.23 EGD86613.2 - 1.4e-17 63.9 0.0 3.6e-17 62.6 0.0 1.7 1 1 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGD86613.2 - 2.7e-12 47.0 0.0 1.1e-11 45.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CUE PF02845.16 EGD86614.1 - 4.3e-12 45.5 0.0 7e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain eRF1_2 PF03464.15 EGD86614.1 - 0.06 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 eRF1 domain 2 CTP_transf_like PF01467.26 EGD86618.1 - 9.5e-30 103.7 0.0 1.9e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 EGD86618.1 - 0.095 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase EamA PF00892.20 EGD86619.1 - 1.4e-22 80.4 22.2 3.9e-13 49.8 6.9 2.4 2 0 0 2 2 2 2 EamA-like transporter family Trp_oprn_chp PF09534.10 EGD86619.1 - 0.044 13.6 0.4 3.2 7.5 0.0 2.6 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PEP-CTERM PF07589.11 EGD86619.1 - 4.5 7.5 11.0 7.8 6.7 0.3 4.1 4 0 0 4 4 4 0 PEP-CTERM motif JAB PF01398.21 EGD86621.2 - 9e-20 70.8 0.0 1.7e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGD86621.2 - 2.6e-08 34.3 0.0 5.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 EGD86621.2 - 0.00018 21.6 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) TFIID-18kDa PF02269.16 EGD86622.1 - 2.5e-23 81.9 0.0 3.8e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.13 EGD86622.1 - 0.011 16.2 0.1 0.021 15.3 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 EGD86622.1 - 0.072 13.5 0.1 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGD86622.1 - 0.081 13.3 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 CENP-S protein PPR_2 PF13041.6 EGD86623.1 - 5.7e-23 80.8 0.1 3.4e-10 39.9 0.0 4.9 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.20 EGD86623.1 - 2.1e-14 52.6 0.2 0.00014 21.9 0.0 4.6 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 EGD86623.1 - 2.2e-09 37.2 0.1 0.00088 19.3 0.0 3.2 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGD86623.1 - 3.6e-09 36.2 0.0 0.00038 20.1 0.0 4.0 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 EGD86623.1 - 1.2e-06 28.1 0.0 0.0017 17.8 0.0 2.5 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP cwf18 PF08315.12 EGD86624.2 - 2.9e-44 151.0 8.9 2.9e-44 151.0 8.9 1.6 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor KicB PF03882.14 EGD86624.2 - 0.051 13.8 0.3 0.12 12.6 0.2 1.8 2 0 0 2 2 2 0 MukF winged-helix domain zf-CCHC_3 PF13917.6 EGD86625.1 - 9.4e-12 44.7 4.3 9.4e-12 44.7 4.3 2.3 2 0 0 2 2 2 1 Zinc knuckle SUZ PF12752.7 EGD86626.2 - 1.5e-14 54.4 13.3 1.5e-14 54.4 13.3 4.1 2 1 1 3 3 3 1 SUZ domain RRM_1 PF00076.22 EGD86627.1 - 2.3e-15 56.2 0.0 3.6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med9 PF07544.13 EGD86627.1 - 0.0061 16.6 0.6 0.01 15.9 0.6 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Spc7 PF08317.11 EGD86627.1 - 0.012 14.6 1.4 0.014 14.3 1.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein EMP24_GP25L PF01105.24 EGD86627.1 - 0.031 14.2 0.7 0.043 13.8 0.7 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Nup35_RRM_2 PF14605.6 EGD86627.1 - 0.05 13.6 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nup54 PF13874.6 EGD86627.1 - 0.064 13.4 0.6 0.084 13.0 0.6 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 V_ATPase_I PF01496.19 EGD86627.1 - 0.18 9.7 0.6 0.2 9.5 0.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 EGD86627.1 - 0.22 11.6 1.8 0.28 11.3 1.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 EGD86627.1 - 1.7 8.5 4.5 2.6 7.9 4.5 1.3 1 0 0 1 1 1 0 Septum formation initiator HECT PF00632.25 EGD86628.2 - 4.8e-90 302.2 0.0 4.6e-89 298.9 0.0 2.0 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EGD86628.2 - 5.3e-33 112.8 31.6 9.9e-13 47.9 5.7 4.7 5 0 0 5 5 5 3 WW domain C2 PF00168.30 EGD86628.2 - 8.8e-20 70.9 0.0 2.3e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain RSS_P20 PF11757.8 EGD86629.1 - 0.02 15.4 0.8 0.095 13.2 0.8 2.0 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain SKA1 PF07160.12 EGD86629.1 - 0.12 12.3 3.2 0.045 13.6 0.9 1.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 HsbA PF12296.8 EGD86629.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Hydrophobic surface binding protein A DUF2203 PF09969.9 EGD86629.1 - 0.29 11.9 3.6 0.64 10.7 0.1 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Aminotran_5 PF00266.19 EGD86630.1 - 7.7e-29 100.8 0.0 1e-28 100.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGD86630.1 - 0.013 14.7 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II KR PF08659.10 EGD86630.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 KR domain NIF PF03031.18 EGD86631.1 - 7.8e-58 194.7 0.0 1.2e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SlyX PF04102.12 EGD86632.1 - 0.055 14.1 0.6 4.5 8.0 0.2 2.4 2 0 0 2 2 2 0 SlyX ATG16 PF08614.11 EGD86632.1 - 1 9.6 5.3 0.15 12.3 0.9 1.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) VGCC_beta4Aa_N PF12052.8 EGD86632.1 - 2.4 8.4 7.2 4.4 7.5 0.9 2.8 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Rhomboid PF01694.22 EGD86633.2 - 1.5e-22 80.2 8.9 2.7e-22 79.4 6.7 2.0 2 0 0 2 2 2 1 Rhomboid family PhoD PF09423.10 EGD86634.1 - 1.1e-07 31.3 0.4 0.0005 19.2 0.1 2.7 2 1 0 2 2 2 2 PhoD-like phosphatase DUF3220 PF11516.8 EGD86634.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Gryzun PF07919.12 EGD86635.2 - 1.9e-208 694.0 0.0 2.1e-208 693.8 0.0 1.0 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 EGD86635.2 - 0.00098 19.1 0.0 0.0028 17.6 0.0 1.8 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Abhydrolase_1 PF00561.20 EGD86636.1 - 9e-09 35.3 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD86636.1 - 0.00026 20.4 0.0 0.0015 17.9 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Glutaredoxin PF00462.24 EGD86637.2 - 2.6e-12 46.8 0.0 4.3e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Ribosomal_L6 PF00347.23 EGD86638.1 - 1.1e-23 83.7 6.6 2e-11 44.4 1.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 RXT2_N PF08595.11 EGD86639.2 - 0.021 14.8 0.0 0.021 14.8 0.0 3.2 2 1 1 3 3 3 0 RXT2-like, N-terminal DNAPolymera_Pol PF11590.8 EGD86639.2 - 0.12 12.3 0.8 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol PEMT PF04191.13 EGD86640.1 - 4.1e-34 117.2 2.2 1.3e-33 115.6 1.2 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF924 PF06041.11 EGD86641.1 - 3.8e-48 164.0 0.1 4.3e-48 163.8 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) SUR7 PF06687.12 EGD86642.2 - 1.9e-34 119.2 9.0 1.9e-34 119.2 9.0 1.3 1 1 0 1 1 1 1 SUR7/PalI family Acetyltransf_1 PF00583.25 EGD86644.1 - 1.5e-11 44.6 0.0 2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGD86644.1 - 2.7e-08 33.8 0.0 3.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD86644.1 - 2.5e-07 30.6 0.0 4.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGD86644.1 - 2.7e-05 24.5 0.0 4.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGD86644.1 - 0.0029 17.7 0.1 0.005 16.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TelA PF05816.11 EGD86645.1 - 0.0033 16.5 4.4 0.0033 16.5 4.4 2.2 3 0 0 3 3 3 1 Toxic anion resistance protein (TelA) Golgin_A5 PF09787.9 EGD86645.1 - 1.2 8.6 33.6 0.062 12.8 11.4 3.0 3 0 0 3 3 3 0 Golgin subfamily A member 5 Macoilin PF09726.9 EGD86645.1 - 1.6 7.2 36.1 3 6.3 36.1 1.5 1 1 0 1 1 1 0 Macoilin family Exonuc_VII_L PF02601.15 EGD86645.1 - 6.1 6.3 19.3 10 5.6 5.9 3.1 3 0 0 3 3 3 0 Exonuclease VII, large subunit Herpes_pp85 PF04637.12 EGD86645.1 - 9.9 4.4 7.6 19 3.5 7.6 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) HEAT PF02985.22 EGD86646.2 - 9.6e-07 28.5 0.1 0.017 15.3 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 EGD86646.2 - 4.7e-06 26.7 0.0 5.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGD86646.2 - 0.0014 19.0 0.0 0.082 13.3 0.0 2.6 1 1 2 3 3 3 1 HEAT repeats Adaptin_N PF01602.20 EGD86646.2 - 0.0028 16.3 0.0 0.49 8.9 0.0 2.0 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 EGD86646.2 - 0.0054 17.2 0.0 0.43 11.1 0.0 3.0 2 1 1 3 3 3 1 HEAT-like repeat CoA_trans PF01144.23 EGD86646.2 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Coenzyme A transferase LsmAD PF06741.13 EGD86649.2 - 4.2e-27 94.5 6.0 4.2e-27 94.5 6.0 2.3 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.6 EGD86649.2 - 2.5e-19 69.2 0.0 5.2e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain AIP3 PF03915.13 EGD86650.2 - 1.9e-153 511.4 2.9 1.9e-153 511.4 2.9 1.6 2 0 0 2 2 2 1 Actin interacting protein 3 MIP-T3_C PF17749.1 EGD86650.2 - 0.0011 19.0 4.6 0.014 15.4 0.6 3.6 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 C-terminal region Lectin_N PF03954.14 EGD86650.2 - 0.064 13.0 2.0 0.17 11.6 0.1 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Syntaxin_2 PF14523.6 EGD86650.2 - 0.47 10.8 7.0 1.8 9.0 0.1 3.9 3 1 0 3 3 3 0 Syntaxin-like protein RasGAP_C PF03836.15 EGD86650.2 - 5.2 7.2 12.1 0.46 10.6 0.3 4.1 5 0 0 5 5 5 0 RasGAP C-terminus ACOX PF01756.19 EGD86652.2 - 1.3e-44 151.9 0.0 2.2e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 EGD86652.2 - 1.9e-07 31.4 0.0 0.00048 20.4 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain ESSS PF10183.9 EGD86653.1 - 7.2e-15 55.1 0.0 8e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RNB PF00773.19 EGD86654.2 - 8.1e-97 324.4 0.1 1.3e-96 323.8 0.1 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 EGD86654.2 - 1.9e-27 95.8 0.1 6.4e-27 94.1 0.1 1.9 1 1 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EGD86654.2 - 2.8e-26 91.3 0.8 7.3e-26 90.0 0.8 1.7 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 EGD86654.2 - 1.2e-21 76.5 0.0 2.9e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EGD86654.2 - 3.4e-11 43.1 0.1 3.1e-07 30.5 0.0 3.0 2 0 0 2 2 2 2 Cold shock domain PIN_4 PF13638.6 EGD86654.2 - 8.6e-08 32.5 0.3 4.3e-07 30.3 0.1 2.2 2 0 0 2 2 2 1 PIN domain MFS_1 PF07690.16 EGD86655.1 - 2.9e-27 95.5 74.4 1e-21 77.3 43.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGD86655.1 - 3.1e-09 35.9 26.2 5.4e-06 25.2 8.4 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EGD86655.1 - 0.0065 15.4 18.0 0.061 12.2 0.3 2.7 2 1 0 2 2 2 2 MFS_1 like family LIM PF00412.22 EGD86656.1 - 3.1e-26 91.3 20.4 2e-10 40.8 2.8 3.9 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.6 EGD86656.1 - 0.0082 16.6 0.1 0.0082 16.6 0.1 2.4 3 0 0 3 3 3 1 Recombinase zinc beta ribbon domain DZR PF12773.7 EGD86656.1 - 4.3 7.5 26.9 84 3.3 4.4 4.6 2 1 1 3 3 3 0 Double zinc ribbon Methyltransf_4 PF02390.17 EGD86657.1 - 2.7e-46 157.2 0.3 4.9e-45 153.1 0.3 2.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EGD86657.1 - 0.0004 21.0 0.0 0.0034 18.0 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD86657.1 - 0.0031 17.3 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGD86657.1 - 0.0035 16.9 0.0 0.079 12.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGD86657.1 - 0.008 16.9 0.0 0.028 15.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD86657.1 - 0.019 15.6 0.0 1.5 9.6 0.0 3.2 4 0 0 4 4 4 0 Methyltransferase domain ESCRT-II PF05871.12 EGD86658.1 - 5.4e-51 172.5 1.3 6.2e-51 172.3 0.6 1.4 2 0 0 2 2 2 1 ESCRT-II complex subunit RTT107_BRCT_5 PF16770.5 EGD86659.1 - 4.1e-35 119.7 0.0 3.5e-31 107.0 0.0 4.2 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 EGD86659.1 - 1.2e-30 105.7 0.0 6.1e-05 23.4 0.0 6.3 6 0 0 6 6 6 6 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGD86659.1 - 1.2e-30 105.2 3.0 2e-17 62.9 0.3 5.7 5 1 0 5 5 5 3 twin BRCT domain BRCT PF00533.26 EGD86659.1 - 3.8e-30 104.1 0.0 1.9e-08 34.5 0.0 6.9 6 1 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGD86659.1 - 5.9e-08 32.9 0.0 0.055 13.8 0.0 4.5 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain Abhydrolase_6 PF12697.7 EGD86660.1 - 2.2e-10 41.5 0.0 3.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGD86660.1 - 0.00079 19.1 0.0 0.48 10.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD86660.1 - 0.00093 18.5 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ceramidase PF05875.12 EGD86661.1 - 5.9e-106 353.7 11.1 7e-106 353.5 11.1 1.0 1 0 0 1 1 1 1 Ceramidase DUF2070 PF09843.9 EGD86661.1 - 0.3 9.3 2.5 0.4 8.9 2.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RTA1 PF04479.13 EGD86663.2 - 1.4e-28 99.9 1.0 2.1e-28 99.4 1.0 1.2 1 0 0 1 1 1 1 RTA1 like protein BTB PF00651.31 EGD86664.2 - 7.7e-05 22.9 0.0 0.00012 22.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain HAD PF12710.7 EGD86665.2 - 1.9e-26 93.6 0.0 2.2e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EGD86665.2 - 8.6e-05 22.2 0.0 0.00061 19.4 0.0 2.0 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 EGD86665.2 - 0.0054 16.2 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.26 EGD86665.2 - 0.13 12.6 1.4 8.8 6.5 0.0 2.9 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HECT PF00632.25 EGD86666.2 - 2.8e-77 260.2 0.0 3.3e-76 256.7 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) MAT1 PF06391.13 EGD86667.1 - 0.37 10.6 7.5 0.7 9.7 7.5 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 F-box-like PF12937.7 EGD86668.1 - 0.0017 18.2 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like Utp14 PF04615.13 EGD86669.1 - 0.12 10.9 32.0 0.31 9.6 18.0 2.2 2 0 0 2 2 2 0 Utp14 protein COesterase PF00135.28 EGD86672.2 - 2.8e-31 109.0 0.0 3.2e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family F-actin_cap_A PF01267.17 EGD86673.2 - 1e-57 195.6 0.0 1.2e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit K_channel_TID PF07941.11 EGD86675.1 - 6.1 7.4 12.1 0.35 11.4 6.4 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain PAP2 PF01569.21 EGD86676.2 - 2.8e-30 104.9 0.3 2.8e-30 104.9 0.3 1.9 2 1 1 3 3 3 2 PAP2 superfamily PAP2_3 PF14378.6 EGD86676.2 - 0.0046 16.7 3.4 0.0046 16.7 3.4 2.1 2 1 0 2 2 2 1 PAP2 superfamily Med7 PF05983.11 EGD86677.1 - 2e-52 178.1 0.3 2e-52 178.1 0.3 1.6 2 0 0 2 2 2 1 MED7 protein RRN3 PF05327.11 EGD86677.1 - 0.026 13.1 1.1 0.031 12.9 1.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HEAT_EZ PF13513.6 EGD86678.2 - 3.3e-19 69.0 2.8 1.2e-05 25.7 0.0 9.4 9 2 2 11 11 11 3 HEAT-like repeat HEAT PF02985.22 EGD86678.2 - 1.4e-18 65.4 4.3 0.0005 20.1 0.1 9.3 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 EGD86678.2 - 3.4e-17 62.6 1.7 0.00039 20.8 0.0 6.9 6 1 1 7 7 7 4 HEAT repeats IFRD PF05004.13 EGD86678.2 - 6.8e-11 41.8 2.8 0.00087 18.5 0.1 4.6 2 1 3 5 5 5 2 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 EGD86678.2 - 5.9e-07 30.0 0.0 1.8 9.2 0.0 6.1 6 1 0 6 6 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGD86678.2 - 1.2e-06 28.6 0.6 1.5 8.9 0.0 4.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EGD86678.2 - 3.3e-06 26.5 0.2 4.3e-05 22.8 0.0 2.9 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal ParcG PF10274.9 EGD86678.2 - 0.00086 19.5 0.1 0.049 13.8 0.1 2.9 2 0 0 2 2 2 1 Parkin co-regulated protein CLASP_N PF12348.8 EGD86678.2 - 0.00092 18.8 1.1 0.12 11.9 0.0 4.0 5 1 0 5 5 5 1 CLASP N terminal RIX1 PF08167.12 EGD86678.2 - 0.0069 16.1 0.8 0.29 10.9 0.0 3.8 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 EGD86678.2 - 0.009 16.2 0.5 2.5 8.3 0.0 4.2 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Ecm29 PF13001.7 EGD86678.2 - 0.015 14.0 0.2 0.28 9.8 0.0 2.8 2 1 0 3 3 3 0 Proteasome stabiliser Tti2 PF10521.9 EGD86678.2 - 0.094 12.2 0.0 2.5 7.6 0.0 3.0 3 1 1 4 4 4 0 Tti2 family Cohesin_HEAT PF12765.7 EGD86678.2 - 0.1 12.9 0.0 0.56 10.6 0.0 2.4 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion 4HB_MCP_1 PF12729.7 EGD86678.2 - 0.15 11.6 0.1 40 3.7 0.0 3.3 2 1 1 3 3 3 0 Four helix bundle sensory module for signal transduction Patched PF02460.18 EGD86679.2 - 5.8e-75 252.9 8.7 2.7e-74 250.7 8.7 1.9 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EGD86679.2 - 3.4e-53 179.6 5.8 3.4e-53 179.6 5.8 3.3 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 EGD86679.2 - 3.5e-23 82.4 0.7 5.5e-23 81.8 0.7 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus MMPL PF03176.15 EGD86679.2 - 2e-07 30.3 8.1 2e-07 30.3 8.1 3.7 4 1 0 4 4 4 1 MMPL family REV1_C PF16727.5 EGD86679.2 - 0.16 12.4 0.2 0.33 11.4 0.2 1.5 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain DUF2433 PF10360.9 EGD86680.1 - 1.2e-48 164.3 0.0 2.1e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 EGD86680.1 - 0.00077 20.0 0.0 0.0017 18.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGD86680.1 - 0.0011 19.2 0.0 0.0041 17.3 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIIA PF03153.13 EGD86680.1 - 0.59 10.1 11.3 1 9.3 11.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP1 PF08601.10 EGD86681.2 - 4.8e-92 309.5 49.1 2.7e-88 297.2 39.9 4.1 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 EGD86681.2 - 5.1e-08 32.9 9.1 1.1e-07 31.8 9.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor SlyX PF04102.12 EGD86681.2 - 0.00062 20.3 0.3 0.0014 19.2 0.3 1.6 1 0 0 1 1 1 1 SlyX DUF16 PF01519.16 EGD86681.2 - 0.0086 16.6 1.4 0.016 15.7 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF16 COG7 PF10191.9 EGD86681.2 - 0.11 10.8 0.1 0.17 10.1 0.1 1.2 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) SHE3 PF17078.5 EGD86681.2 - 0.11 12.2 3.1 0.19 11.4 3.1 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 EGD86681.2 - 0.17 12.4 10.1 0.44 11.1 10.1 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor TSC22 PF01166.18 EGD86681.2 - 0.28 11.5 0.9 0.59 10.5 0.9 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Tudor_3 PF18115.1 EGD86682.2 - 2e-07 30.7 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EGD86682.2 - 0.0042 17.1 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 EGD86682.2 - 0.16 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain ParA PF10609.9 EGD86684.1 - 6.1e-82 274.8 0.0 2.9e-50 171.0 0.0 2.8 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGD86684.1 - 1e-12 48.2 0.0 4.3e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGD86684.1 - 8e-10 38.9 0.1 9e-08 32.2 0.1 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EGD86684.1 - 2.2e-06 27.2 0.1 3.5e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EGD86684.1 - 0.00022 20.5 0.5 0.0018 17.5 0.3 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.6 EGD86684.1 - 0.0026 17.4 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EGD86684.1 - 0.029 13.8 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 EGD86684.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein Abhydrolase_3 PF07859.13 EGD86686.2 - 1.2e-24 87.3 0.0 1.1e-15 58.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold TRAUB PF08164.12 EGD86686.2 - 2.6e-24 85.5 0.0 8.2e-24 83.9 0.0 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Say1_Mug180 PF10340.9 EGD86686.2 - 3.7e-12 45.8 0.0 7.4e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EGD86686.2 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 WGG PF10273.9 EGD86687.1 - 1.9e-28 98.9 0.1 3.4e-28 98.1 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 EGD86687.1 - 0.13 12.4 1.9 0.15 12.2 0.7 1.8 2 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain CDC45 PF02724.14 EGD86687.1 - 0.22 9.8 7.6 0.24 9.6 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EGD86687.1 - 0.29 10.4 5.4 0.36 10.1 5.4 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EGD86687.1 - 2 8.8 11.4 4.1 7.9 11.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tht1 PF04163.12 EGD86688.1 - 1.2e-08 34.2 10.2 2.3e-07 30.0 6.1 3.1 2 1 0 2 2 2 1 Tht1-like nuclear fusion protein DUF2243 PF10002.9 EGD86688.1 - 0.0012 19.0 7.4 0.0025 17.9 7.4 1.6 1 1 0 1 1 1 1 Predicted membrane protein (DUF2243) DUF885 PF05960.11 EGD86688.1 - 0.0089 15.7 1.5 0.014 15.0 1.5 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Spore_IV_A PF09547.10 EGD86688.1 - 0.017 14.1 0.3 0.027 13.4 0.3 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) BLOC1_2 PF10046.9 EGD86688.1 - 0.17 12.2 6.5 38 4.7 0.1 3.7 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0122 PF04297.14 EGD86688.1 - 0.34 11.2 2.1 0.64 10.3 0.2 2.3 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like DASH_Dad1 PF08649.10 EGD86688.1 - 0.35 11.1 2.0 2 8.7 0.2 3.0 2 1 0 2 2 2 0 DASH complex subunit Dad1 Peptidase_S46 PF10459.9 EGD86688.1 - 0.58 8.7 5.4 0.88 8.1 5.4 1.2 1 0 0 1 1 1 0 Peptidase S46 Peptidase_U4 PF03419.13 EGD86688.1 - 0.89 8.8 13.0 1.5 8.0 13.0 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA SATase_N PF06426.14 EGD86688.1 - 2 8.8 10.3 11 6.4 0.1 3.9 2 1 2 4 4 4 0 Serine acetyltransferase, N-terminal Baculo_PEP_C PF04513.12 EGD86688.1 - 3.7 7.6 15.8 4.7 7.3 0.5 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EGD86688.1 - 4.4 7.8 6.7 60 4.2 0.1 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Ribosomal_L6 PF00347.23 EGD86689.1 - 6e-20 71.7 0.0 2.8e-09 37.5 0.0 2.5 2 1 0 2 2 2 2 Ribosomal protein L6 GAT PF03127.14 EGD86691.2 - 0.03 14.6 0.4 0.074 13.4 0.4 1.7 1 0 0 1 1 1 0 GAT domain Flagellin_C PF00700.21 EGD86691.2 - 0.11 12.8 0.2 0.22 11.9 0.2 1.4 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region ATG16 PF08614.11 EGD86691.2 - 2.9 8.1 10.9 0.33 11.2 6.1 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) adh_short_C2 PF13561.6 EGD86692.1 - 7.2e-42 143.5 0.4 2.9e-40 138.3 0.4 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD86692.1 - 9.7e-39 132.8 0.1 2.6e-38 131.5 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD86692.1 - 5.1e-09 36.3 1.7 2.9e-07 30.6 0.1 2.3 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 EGD86692.1 - 0.00013 22.0 0.1 0.00021 21.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox PF00070.27 EGD86692.1 - 0.016 15.7 1.9 0.053 14.1 0.5 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1776 PF08643.10 EGD86692.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.4 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) DUF4536 PF15055.6 EGD86692.1 - 0.11 12.8 1.6 2.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) GDP_Man_Dehyd PF16363.5 EGD86692.1 - 0.11 11.9 0.2 0.62 9.4 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Hva1_TUDOR PF11160.8 EGD86693.1 - 2.6e-19 69.1 0.2 3e-19 68.9 0.2 1.0 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain CP2 PF04516.15 EGD86695.2 - 6.6e-61 205.5 0.0 8.3e-61 205.2 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor Helicase_C PF00271.31 EGD86696.2 - 8.2e-27 93.8 0.0 3.2e-26 91.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGD86696.2 - 9.4e-08 32.0 0.0 2.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGD86696.2 - 0.039 14.2 0.3 0.37 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain FAD_binding_1 PF00667.20 EGD86698.2 - 6.3e-54 182.9 0.0 8.9e-54 182.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EGD86698.2 - 2.8e-09 37.6 0.0 1.1e-08 35.7 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain BCAS2 PF05700.11 EGD86699.1 - 0.039 13.7 1.7 0.039 13.7 1.7 1.6 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) SHE3 PF17078.5 EGD86699.1 - 0.044 13.5 2.8 0.053 13.2 2.8 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 RuvC PF02075.17 EGD86699.1 - 0.12 12.2 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC Mvb12 PF09452.10 EGD86699.1 - 0.27 11.7 2.2 1.4 9.4 0.1 2.0 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 ketoacyl-synt PF00109.26 EGD86700.2 - 2.8e-20 73.0 0.0 2.7e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain KAsynt_C_assoc PF16197.5 EGD86700.2 - 5.4e-14 52.6 0.0 1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Ketoacyl-synt_C PF02801.22 EGD86700.2 - 1.1e-10 41.6 0.3 1.6e-08 34.6 0.2 2.5 1 1 1 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 EGD86700.2 - 7.3e-09 35.7 0.0 2.4e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Acyl_transf_1 PF00698.21 EGD86700.2 - 0.0002 21.0 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ADH_N PF08240.12 EGD86700.2 - 0.016 15.1 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 EGD86701.2 - 3.7e-46 157.7 60.1 3.7e-46 157.7 60.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD86701.2 - 1.8e-17 63.4 13.7 1.8e-17 63.4 13.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EGD86701.2 - 1.2e-12 47.0 24.8 2.8e-12 45.9 25.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EGD86701.2 - 0.3 9.3 17.2 0.055 11.8 1.3 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3522 PF12036.8 EGD86701.2 - 0.72 10.1 8.6 2.1 8.6 4.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) Proteasome PF00227.26 EGD86702.1 - 9.5e-61 204.6 0.1 1.2e-60 204.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGD86702.1 - 2.6e-13 49.3 0.1 8.7e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 EGD86702.1 - 0.012 15.7 0.3 0.03 14.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 EGD86702.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FF PF01846.19 EGD86703.2 - 2.4e-13 50.0 6.9 5.9e-10 39.2 0.1 3.8 3 0 0 3 3 3 3 FF domain DUF5641 PF18701.1 EGD86703.2 - 0.00033 20.8 0.8 0.001 19.2 0.8 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5641) BPL_N PF09825.9 EGD86703.2 - 0.52 9.3 8.7 0.49 9.4 7.2 1.7 1 1 0 1 1 1 0 Biotin-protein ligase, N terminal DASH_Dam1 PF08653.10 EGD86704.1 - 0.14 12.0 0.2 0.23 11.3 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 AbiH PF14253.6 EGD86704.1 - 0.15 11.9 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH SPOC PF07744.13 EGD86706.2 - 3.2e-25 88.8 0.0 6.1e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 EGD86706.2 - 5.7e-21 75.1 0.0 9.4e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain LUC7 PF03194.15 EGD86707.2 - 4.1e-70 236.3 1.4 7e-69 232.3 0.1 2.0 1 1 1 2 2 2 1 LUC7 N_terminus TelA PF05816.11 EGD86707.2 - 0.0047 16.0 0.5 0.008 15.3 0.5 1.3 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DASH_Duo1 PF08651.10 EGD86707.2 - 0.068 12.9 0.9 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF3584 PF12128.8 EGD86707.2 - 0.07 10.6 0.1 0.094 10.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) T4SS PF07996.11 EGD86707.2 - 0.1 13.0 0.1 0.33 11.3 0.0 1.8 1 1 1 2 2 2 0 Type IV secretion system proteins DUF2130 PF09903.9 EGD86707.2 - 0.1 11.8 0.3 0.18 11.0 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Glutaredoxin2_C PF04399.13 EGD86707.2 - 0.11 12.3 0.0 0.69 9.8 0.0 2.0 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain DegS PF05384.11 EGD86707.2 - 0.12 11.9 0.3 1.3 8.5 0.1 2.4 3 0 0 3 3 3 0 Sensor protein DegS PP_kinase_N PF13089.6 EGD86707.2 - 0.13 12.6 0.1 0.67 10.3 0.0 2.0 1 1 1 2 2 2 0 Polyphosphate kinase N-terminal domain GRP PF07172.11 EGD86707.2 - 0.18 12.5 18.4 0.3 11.8 18.4 1.4 1 0 0 1 1 1 0 Glycine rich protein family MCPsignal PF00015.21 EGD86707.2 - 0.19 11.5 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain XhlA PF10779.9 EGD86707.2 - 0.23 11.7 2.5 0.39 10.9 0.6 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Gpi16 PF04113.14 EGD86708.1 - 4.1e-231 768.3 0.0 5.2e-231 767.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component VMA21 PF09446.10 EGD86709.1 - 2.7e-11 43.4 6.7 3.7e-11 43.0 6.7 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF2406 PF10295.9 EGD86710.1 - 2e-26 92.4 0.1 2e-26 92.4 0.1 3.0 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) Ribosomal_L35Ae PF01247.18 EGD86711.2 - 3.5e-41 139.3 0.4 4.4e-41 138.9 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EGD86711.2 - 0.0022 18.2 0.0 0.98 9.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain SRF-TF PF00319.18 EGD86712.1 - 1.9e-23 81.7 0.3 2.9e-23 81.1 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1708 PF08101.11 EGD86713.2 - 2e-139 465.5 0.0 3.2e-139 464.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF3602 PF12223.8 EGD86714.1 - 3.5e-24 85.2 10.4 1.2e-22 80.3 3.3 2.6 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 EGD86714.1 - 2.1 8.0 11.1 0.84 9.2 0.5 2.7 2 1 1 3 3 3 0 GTP1/OBG YqhR PF11085.8 EGD86717.1 - 0.048 13.6 2.2 0.12 12.3 2.2 1.6 1 0 0 1 1 1 0 Conserved membrane protein YqhR BBE PF08031.12 EGD86718.2 - 0.00049 20.1 0.3 0.0012 18.9 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like UvrA_DNA-bind PF17755.1 EGD86718.2 - 0.094 13.1 0.1 0.2 12.0 0.1 1.5 1 1 0 1 1 1 0 UvrA DNA-binding domain ERG4_ERG24 PF01222.17 EGD86719.2 - 4.3e-147 490.3 16.4 5.4e-147 490.0 16.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Peptidase_M43 PF05572.13 EGD86721.1 - 3.7e-16 59.4 0.2 7.5e-16 58.4 0.2 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 EGD86721.1 - 1.4e-06 28.8 1.0 1.2e-05 25.8 1.0 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EGD86721.1 - 5e-06 26.8 2.1 1.1e-05 25.7 2.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EGD86721.1 - 0.00065 19.4 2.3 0.0047 16.6 2.3 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EGD86721.1 - 0.0047 16.8 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.6 EGD86721.1 - 0.033 14.1 1.0 0.061 13.2 0.6 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EGD86721.1 - 0.035 13.0 0.1 0.056 12.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.24 EGD86721.1 - 0.071 12.7 0.1 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) DUF4953 PF16313.5 EGD86721.1 - 0.12 11.6 0.1 0.25 10.5 0.1 1.4 1 0 0 1 1 1 0 Met-zincin KCH PF16944.5 EGD86722.2 - 7.7e-89 297.8 5.2 9.3e-89 297.5 5.2 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF747 PF05346.11 EGD86723.1 - 1.4e-118 396.0 8.0 1.8e-118 395.6 8.0 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF1189 PF06691.11 EGD86723.1 - 6.9 6.2 10.3 0.26 10.8 2.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1189) p450 PF00067.22 EGD86724.1 - 6e-72 242.8 0.0 7.5e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M20 PF01546.28 EGD86725.2 - 8.8e-22 77.8 0.0 2.7e-20 73.0 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGD86725.2 - 4e-05 23.5 0.0 9e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGD86725.2 - 0.0005 19.8 0.0 0.00096 18.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TraQ PF09679.10 EGD86727.1 - 0.045 13.7 1.5 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Dsh_C PF12316.8 EGD86727.1 - 0.42 11.0 17.2 2.7 8.4 4.8 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Tim17 PF02466.19 EGD86728.1 - 2e-32 111.9 8.4 2.5e-32 111.5 8.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.6 EGD86728.1 - 0.18 11.9 0.0 0.48 10.6 0.0 1.7 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal Asparaginase_2 PF01112.18 EGD86729.1 - 8.7e-52 176.0 0.0 3e-50 171.0 0.0 3.1 2 1 0 2 2 2 1 Asparaginase p450 PF00067.22 EGD86730.1 - 1.2e-65 222.1 0.0 1.4e-65 221.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.22 EGD86731.1 - 1.2e-29 103.6 14.4 2.6e-29 102.4 14.4 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGD86731.1 - 1.4e-15 57.7 0.0 2.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Flavoprotein PF02441.19 EGD86732.1 - 1.2e-12 47.8 0.0 2.1e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.6 EGD86732.1 - 0.0059 17.2 0.2 42 4.9 0.0 4.3 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Dimer_Tnp_hAT PF05699.14 EGD86732.1 - 6.7 6.6 7.7 8.1 6.3 0.0 4.0 4 1 1 5 5 5 0 hAT family C-terminal dimerisation region MFS_1 PF07690.16 EGD86733.1 - 1e-45 156.2 45.9 1e-45 156.2 45.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD86733.1 - 1.5e-15 57.0 14.3 1.5e-15 57.0 14.3 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EGD86733.1 - 0.1 11.4 24.8 0.012 14.5 10.0 2.7 2 1 0 2 2 2 0 MFS_1 like family Cerato-platanin PF07249.12 EGD86734.1 - 7.3e-44 148.7 0.3 8.9e-44 148.4 0.3 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 EGD86734.1 - 0.016 15.0 0.2 0.024 14.5 0.2 1.5 1 1 0 1 1 1 0 Barwin family D123 PF07065.14 EGD86736.1 - 0.0062 15.7 0.0 0.029 13.5 0.0 1.9 1 1 0 1 1 1 1 D123 R2K_3 PF14243.6 EGD86736.1 - 0.011 15.8 0.0 0.038 14.0 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 EGD86736.1 - 0.03 14.2 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 DUF2011 PF09428.10 EGD86738.2 - 2.7e-29 101.2 0.4 7.5e-29 99.8 0.0 1.9 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF2011) Radial_spoke_3 PF06098.11 EGD86738.2 - 4.8 6.4 12.3 7.5 5.7 12.3 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 LAMTOR PF15454.6 EGD86739.2 - 5.5e-05 23.7 0.0 9.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator UQ_con PF00179.26 EGD86741.2 - 5.2e-14 52.1 0.0 6.8e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme APG12 PF04110.13 EGD86744.1 - 6.5e-27 93.8 0.0 9e-27 93.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EGD86744.1 - 0.037 14.2 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.15 EGD86745.1 - 3.6e-107 357.6 1.8 4.3e-107 357.3 1.8 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EGD86745.1 - 1.9e-10 40.6 1.2 2e-10 40.5 0.2 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase YjcQ PF09639.10 EGD86745.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 YjcQ protein Dfp1_Him1_M PF08630.10 EGD86746.2 - 5.7e-36 123.5 0.0 5.7e-36 123.5 0.0 2.2 2 1 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 EGD86746.2 - 7.5e-20 70.8 0.4 1.2e-19 70.2 0.4 1.3 1 0 0 1 1 1 1 DBF zinc finger FR47 PF08445.10 EGD86748.1 - 2.1e-09 37.2 0.1 6.6e-05 22.8 0.0 2.5 1 1 1 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.7 EGD86748.1 - 6e-06 27.0 0.0 1.5e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGD86748.1 - 3.1e-05 24.2 0.1 0.00015 22.0 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGD86748.1 - 0.044 14.2 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGD86748.1 - 0.087 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_zinc_N PF00107.26 EGD86749.2 - 1.8e-18 66.8 0.0 1.8e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGD86749.2 - 4.3e-05 24.6 0.0 5.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyridox_ox_2 PF12900.7 EGD86750.1 - 5.7e-37 126.8 0.0 8.4e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SIR2 PF02146.17 EGD86751.1 - 1.8e-37 129.0 0.0 9.8e-37 126.6 0.0 1.9 1 1 0 1 1 1 1 Sir2 family MFS_1 PF07690.16 EGD86753.1 - 3.2e-17 62.5 10.9 6.4e-11 41.8 9.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGD86753.1 - 0.0011 17.4 2.0 0.085 11.1 0.1 2.2 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 EGD86754.1 - 6.2e-18 64.8 47.2 1.1e-11 44.2 14.1 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily PALP PF00291.25 EGD86755.2 - 3.1e-12 46.5 1.1 1.7e-11 44.1 1.1 2.1 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Mtd_N PF18454.1 EGD86756.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Major tropism determinant N-terminal domain SRR1 PF07985.12 EGD86757.2 - 3.2e-06 27.1 0.0 4.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 SRR1 Mad3_BUB1_I PF08311.12 EGD86757.2 - 0.097 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 SNF2_N PF00176.23 EGD86758.1 - 9.2e-67 225.2 0.0 5.4e-65 219.4 0.0 2.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGD86758.1 - 9.1e-16 58.2 0.0 3.9e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGD86758.1 - 1.6e-05 24.7 0.0 4.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGD86758.1 - 8.3e-05 22.6 0.0 0.00028 20.9 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PPV_E1_N PF00524.18 EGD86758.1 - 0.35 11.3 5.6 0.091 13.2 0.7 2.5 2 0 0 2 2 2 0 E1 Protein, N terminal domain RPN2_C PF18004.1 EGD86758.1 - 0.52 10.2 15.4 5.2 7.0 0.0 3.7 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3736 PF12540.8 EGD86758.1 - 1.4 9.1 8.2 0.48 10.5 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) Cwf_Cwc_15 PF04889.12 EGD86758.1 - 5 6.8 27.1 0.48 10.1 12.7 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 EGD86760.2 - 9.3e-51 172.7 0.0 1.3e-50 172.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD86760.2 - 3.8e-26 91.9 0.0 5.1e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD86760.2 - 3e-06 26.8 0.0 4.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGD86760.2 - 0.0002 20.3 0.0 0.00029 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGD86760.2 - 0.0046 16.9 2.1 0.011 15.7 0.2 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGD86760.2 - 0.017 14.5 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGD86760.2 - 0.038 12.9 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGD86760.2 - 0.16 11.0 0.1 0.23 10.5 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 ETRAMP PF09716.10 EGD86761.2 - 0.6 10.2 7.5 1.7 8.7 1.1 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CEND1 PF15677.5 EGD86761.2 - 0.65 10.5 0.0 0.65 10.5 0.0 2.9 3 0 0 3 3 3 0 Cell cycle exit and neuronal differentiation protein 1 DUF3899 PF13038.6 EGD86761.2 - 3.8 8.1 0.0 3.8 8.1 0.0 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF3899) DUF3139 PF11337.8 EGD86761.2 - 8.1 7.2 8.9 18 6.0 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Shisa PF13908.6 EGD86762.1 - 0.00063 20.0 0.0 0.0008 19.7 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4050 PF13259.6 EGD86762.1 - 0.047 14.0 0.2 0.062 13.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) SLATT_3 PF18184.1 EGD86762.1 - 0.053 13.7 0.0 0.74 9.9 0.0 2.4 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 3 CCT PF06203.14 EGD86762.1 - 0.14 12.2 0.8 0.3 11.2 0.8 1.5 1 0 0 1 1 1 0 CCT motif CD99L2 PF12301.8 EGD86762.1 - 0.17 12.2 0.2 0.17 12.2 0.2 1.8 1 1 0 2 2 2 0 CD99 antigen like protein 2 DUF1310 PF07006.11 EGD86762.1 - 0.2 11.6 0.6 0.29 11.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) DUF4231 PF14015.6 EGD86763.2 - 0.14 12.6 0.4 1.4 9.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Fib_alpha PF08702.10 EGD86764.2 - 0.0063 16.7 2.9 0.0063 16.7 2.9 2.9 2 1 1 3 3 3 2 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EGD86764.2 - 0.097 12.7 11.7 0.34 10.9 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) VGPC1_C PF16799.5 EGD86764.2 - 0.21 11.6 8.2 0.34 10.9 0.8 3.8 3 1 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF2785 PF10978.8 EGD86764.2 - 0.63 9.8 6.4 0.23 11.2 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2785) CorA PF01544.18 EGD86764.2 - 1.6 7.9 11.3 0.23 10.7 1.9 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein SHE3 PF17078.5 EGD86764.2 - 3.3 7.4 30.2 0.87 9.3 5.2 2.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF2207 PF09972.9 EGD86764.2 - 4.7 5.8 6.2 1.5 7.5 0.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) HTH_37 PF13744.6 EGD86766.1 - 0.053 13.5 1.7 0.13 12.2 0.6 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Med13_N PF11597.8 EGD86767.2 - 1.6e-33 116.4 0.2 3.1e-33 115.5 0.2 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 EGD86767.2 - 6.5e-06 26.1 0.2 5.1e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 MID domain of medPIWI NUC153 PF08159.12 EGD86768.2 - 4.3e-10 39.2 1.1 9.2e-10 38.2 1.1 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EGD86768.2 - 0.00019 22.2 0.0 0.56 11.2 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD86768.2 - 0.0028 17.9 0.0 0.019 15.2 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Sulfotransfer_4 PF17784.1 EGD86769.1 - 8.8e-74 247.9 0.0 1.1e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGD86769.1 - 0.00048 20.6 0.6 0.054 13.9 0.0 2.6 1 1 0 2 2 2 2 Sulfotransferase family Lipase3_N PF03893.16 EGD86769.1 - 0.13 12.3 0.1 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Lipase 3 N-terminal region SET PF00856.28 EGD86772.1 - 1.4e-14 54.8 2.0 6e-14 52.8 0.0 2.9 2 2 0 2 2 2 1 SET domain TPR_2 PF07719.17 EGD86772.1 - 0.0011 18.9 4.8 0.059 13.5 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGD86772.1 - 0.0015 18.8 1.8 0.0045 17.2 1.8 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGD86772.1 - 0.0086 16.8 0.0 0.057 14.3 0.0 2.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGD86772.1 - 0.011 15.9 3.5 0.037 14.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGD86772.1 - 0.031 14.1 3.3 0.61 10.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PDZ_6 PF17820.1 EGD86772.1 - 0.036 13.9 0.0 14 5.6 0.0 2.9 3 0 0 3 3 3 0 PDZ domain TPR_16 PF13432.6 EGD86772.1 - 0.23 12.1 4.1 1.9 9.2 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat FAD_binding_4 PF01565.23 EGD86773.1 - 6.4e-26 90.8 0.3 1.3e-25 89.8 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGD86773.1 - 8.9e-06 25.7 0.0 2.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like ATG13 PF10033.9 EGD86774.1 - 2.1e-67 227.3 0.0 3.2e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 RCC1 PF00415.18 EGD86776.1 - 9.9e-24 83.7 0.0 6.9e-07 29.8 0.0 5.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EGD86776.1 - 1.5e-13 50.9 0.3 4.4e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 EGD86776.1 - 9.4e-10 38.0 4.4 1.9e-08 33.9 0.1 4.1 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 EGD86776.1 - 6.5e-06 26.6 0.1 0.00022 21.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGD86776.1 - 0.0033 17.7 0.0 0.082 13.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGD86776.1 - 0.0074 16.9 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGD86776.1 - 0.015 15.8 0.1 2 9.3 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat TCO89 PF10452.9 EGD86777.1 - 0.0064 15.5 16.1 0.02 13.9 1.9 3.1 2 2 0 2 2 2 2 TORC1 subunit TCO89 PBP1_TM PF14812.6 EGD86777.1 - 0.03 14.7 5.1 0.13 12.6 0.6 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VHS PF00790.19 EGD86778.1 - 3.1e-42 143.8 3.1 1.5e-41 141.5 0.3 2.5 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 EGD86778.1 - 2.9e-16 59.4 1.3 5.1e-16 58.6 1.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EGD86778.1 - 6.7e-07 28.8 10.5 0.0012 18.6 1.9 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 EGD86778.1 - 8.4e-06 26.0 0.3 7.1e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 GAT domain Npa1 PF11707.8 EGD86778.1 - 0.017 14.5 0.1 0.035 13.5 0.1 1.5 1 1 0 1 1 1 0 Ribosome 60S biogenesis N-terminal FYVE_2 PF02318.16 EGD86778.1 - 0.053 13.7 0.3 0.14 12.4 0.3 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger OrfB_Zn_ribbon PF07282.11 EGD86778.1 - 1.2 9.2 4.9 1.4 8.9 3.6 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Fer4_2 PF12797.7 EGD86778.1 - 2.6 8.3 4.3 1.9 8.8 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain UCH PF00443.29 EGD86779.2 - 2.2e-53 181.4 0.1 3.6e-53 180.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGD86779.2 - 5.5e-18 65.6 0.9 5.9e-15 55.7 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EGD86779.2 - 0.00011 22.7 0.0 0.00027 21.4 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain HSP70 PF00012.20 EGD86780.1 - 1.1e-259 862.7 13.0 1.2e-259 862.5 13.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGD86780.1 - 2.5e-18 66.0 1.4 3.5e-17 62.2 0.6 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 EGD86780.1 - 0.0025 16.9 0.4 0.032 13.2 0.3 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 EGD86780.1 - 0.01 15.1 1.6 0.95 8.7 0.2 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EGD86780.1 - 0.016 14.7 0.1 0.74 9.3 0.0 2.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 EGD86780.1 - 0.089 12.5 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 EGD86780.1 - 0.15 11.3 2.6 0.88 8.7 0.0 2.6 2 1 0 3 3 3 0 StbA protein FtsA PF14450.6 EGD86780.1 - 0.67 10.4 8.0 9.8 6.7 0.2 3.5 3 2 0 3 3 3 0 Cell division protein FtsA FIVAR PF07554.13 EGD86780.1 - 1.9 9.3 8.9 3.3 8.5 1.2 3.8 4 0 0 4 4 4 0 FIVAR domain GTP_EFTU PF00009.27 EGD86781.2 - 8.7e-50 169.0 0.0 1.9e-49 167.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EGD86781.2 - 5.6e-20 71.4 8.1 1.2e-19 70.4 8.1 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 EGD86781.2 - 1.4e-09 38.2 0.1 6.4e-09 36.1 0.0 2.3 2 0 0 2 2 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGD86781.2 - 3.2e-08 33.8 0.0 1.4e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGD86781.2 - 1.3e-07 31.7 0.0 3.2e-06 27.2 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EGD86781.2 - 0.00013 21.5 0.1 0.032 13.7 0.0 2.4 1 1 1 2 2 2 2 ADP-ribosylation factor family Ras PF00071.22 EGD86781.2 - 0.00075 19.1 0.2 0.019 14.6 0.0 2.4 1 1 1 2 2 2 1 Ras family SRPRB PF09439.10 EGD86781.2 - 0.0031 17.0 0.1 0.44 10.0 0.1 2.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGD86781.2 - 0.0039 16.7 0.2 0.19 11.3 0.2 3.2 3 1 0 3 3 3 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 EGD86781.2 - 0.0049 16.3 0.1 0.011 15.1 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGD86781.2 - 0.0052 16.7 0.5 0.54 10.1 0.2 2.5 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 EGD86781.2 - 0.0083 16.3 0.1 3.3 8.0 0.0 2.8 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGD86781.2 - 0.031 13.4 0.6 0.98 8.5 0.0 2.9 3 0 0 3 3 3 0 G-protein alpha subunit Cyt-b5 PF00173.28 EGD86782.1 - 2.4e-24 85.3 0.1 3.1e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain K_trans PF02705.16 EGD86783.2 - 3.8e-168 560.3 23.3 4.6e-168 560.0 23.3 1.0 1 0 0 1 1 1 1 K+ potassium transporter VHS PF00790.19 EGD86784.1 - 1.6e-36 125.2 1.5 2.7e-36 124.5 1.5 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EGD86784.1 - 1e-17 63.5 0.1 7.3e-17 60.7 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGD86784.1 - 3e-15 55.8 0.1 5.9e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGD86784.1 - 3.8e-13 48.9 0.1 1.1e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain GAT PF03127.14 EGD86784.1 - 4.1e-10 39.8 1.5 4.1e-10 39.8 1.5 2.4 2 1 0 2 2 2 1 GAT domain DUF4598 PF15370.6 EGD86784.1 - 0.013 16.0 0.8 0.035 14.6 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) UIM PF02809.20 EGD86784.1 - 0.02 14.8 1.4 0.052 13.5 1.4 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF3361 PF11841.8 EGD86784.1 - 0.49 10.3 2.2 0.43 10.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Pkinase PF00069.25 EGD86785.1 - 1.3e-71 241.1 0.0 2.5e-71 240.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD86785.1 - 1.2e-44 152.6 0.7 1.9e-44 151.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 EGD86785.1 - 5.2e-22 78.0 0.4 1.7e-21 76.3 0.4 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EGD86785.1 - 1.9e-06 27.5 0.0 3.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGD86785.1 - 1.9e-06 26.9 0.0 1.9e-06 26.9 0.0 2.6 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 EGD86785.1 - 0.036 14.0 0.1 0.57 10.1 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGD86785.1 - 0.047 13.0 0.2 0.047 13.0 0.2 1.8 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.12 EGD86785.1 - 0.065 12.9 1.2 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 DSHCT (NUC185) domain FTA2 PF13095.6 EGD86785.1 - 0.44 10.1 0.0 0.44 10.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EGD86785.1 - 0.89 8.4 9.8 0.43 9.5 1.3 3.0 2 1 0 2 2 2 0 Haspin like kinase domain KH_1 PF00013.29 EGD86786.1 - 7.7e-99 323.6 14.8 1e-12 47.7 0.4 13.7 13 2 0 13 13 13 9 KH domain SLS PF14611.6 EGD86786.1 - 4.3e-11 43.1 0.3 0.22 11.3 0.0 7.2 3 3 5 8 8 8 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EGD86786.1 - 9.9e-10 38.1 18.2 0.0024 17.7 0.0 8.3 8 1 0 8 8 8 3 KH domain KH_4 PF13083.6 EGD86786.1 - 0.00045 20.0 5.4 17 5.4 0.1 6.0 7 0 0 7 7 7 2 KH domain BMC PF00936.19 EGD86786.1 - 0.14 12.2 6.3 0.35 10.9 0.2 4.1 5 0 0 5 5 5 0 BMC domain DUF3632 PF12311.8 EGD86788.1 - 2.4e-15 57.4 0.0 2.4e-14 54.2 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3632) YlbD_coat PF14071.6 EGD86788.1 - 6.1 7.1 9.2 0.12 12.6 0.7 2.4 3 1 0 3 3 3 0 Putative coat protein PP2C PF00481.21 EGD86791.1 - 8.4e-53 179.6 0.0 1.2e-52 179.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EGD86791.1 - 7.1e-41 137.8 63.7 1.3e-11 44.0 7.7 11.0 7 3 6 13 13 13 10 Leucine rich repeat LRR_4 PF12799.7 EGD86791.1 - 1e-36 124.3 67.3 3e-06 27.5 2.3 12.3 7 2 7 14 14 14 13 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EGD86791.1 - 4e-27 95.0 0.0 2.7e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 EGD86791.1 - 4.9e-09 35.9 16.4 0.0039 16.7 1.1 4.8 2 1 3 5 5 5 5 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 EGD86791.1 - 2e-08 33.8 0.0 8.4e-08 31.8 0.0 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 EGD86791.1 - 5.2e-08 32.4 61.0 2.1 9.2 0.1 15.8 16 2 0 16 16 16 4 Leucine Rich Repeat LRR_5 PF13306.6 EGD86791.1 - 6.9e-06 26.1 4.4 0.057 13.4 0.2 4.0 3 1 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EGD86791.1 - 0.0005 19.9 48.2 4.3 7.7 0.3 13.4 15 0 0 15 15 15 4 Leucine Rich repeat RA PF00788.23 EGD86791.1 - 0.059 14.0 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain tRNA-synt_1b PF00579.25 EGD86793.2 - 3.3e-66 223.6 0.0 4.3e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Glyco_hydro_16 PF00722.21 EGD86795.2 - 1.3e-23 83.3 0.0 1.8e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 EGD86798.1 - 3.7e-35 121.5 25.4 5.6e-35 120.9 25.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2681 PF10883.8 EGD86798.1 - 0.051 14.0 0.8 1.1 9.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) S4 PF01479.25 EGD86800.1 - 1.9e-11 43.4 0.0 3.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 EGD86800.1 - 5.6e-10 40.0 3.1 8.5e-10 39.4 2.6 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain PilP PF04351.13 EGD86800.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.6 2 0 0 2 2 2 0 Pilus assembly protein, PilP ADH_zinc_N PF00107.26 EGD86801.1 - 6.9e-08 32.5 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGD86801.1 - 0.0028 17.5 0.2 0.0066 16.3 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Spore_YpjB PF09577.10 EGD86803.2 - 0.084 12.7 0.4 0.14 11.9 0.4 1.3 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) LPAM_1 PF08139.12 EGD86804.1 - 0.83 10.3 2.5 2.8 8.6 2.5 2.0 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DnaJ PF00226.31 EGD86805.1 - 1.8e-23 82.4 2.4 2.9e-23 81.7 2.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EGD86805.1 - 5.2e-23 81.8 0.0 7.6e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EGD86805.1 - 7e-12 45.5 13.7 1.1e-11 44.8 13.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGD86805.1 - 0.0043 17.0 7.0 0.018 15.0 1.3 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGD86805.1 - 0.075 13.1 6.0 2.8 8.0 0.9 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4449 PF14613.6 EGD86806.2 - 1.3e-05 25.3 3.7 7.9e-05 22.8 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Ku_PK_bind PF08785.11 EGD86806.2 - 0.008 16.3 1.3 0.1 12.7 0.0 3.1 4 0 0 4 4 4 1 Ku C terminal domain like MCPVI PF02993.14 EGD86806.2 - 0.1 12.4 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 Minor capsid protein VI Kinesin PF00225.23 EGD86807.2 - 5.4e-54 183.3 0.0 1.2e-53 182.2 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGD86807.2 - 4.3e-06 26.7 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding SAM_PNT PF02198.16 EGD86807.2 - 0.047 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Malic_M PF03949.15 EGD86808.2 - 4.1e-92 308.1 0.0 5.4e-92 307.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EGD86808.2 - 2.4e-64 216.5 0.0 4.2e-64 215.7 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PTR2 PF00854.21 EGD86809.1 - 8.5e-96 321.2 10.6 2.6e-95 319.6 10.6 1.7 1 1 0 1 1 1 1 POT family THOC7 PF05615.13 EGD86810.1 - 1.1e-45 155.2 8.5 1.1e-45 155.2 8.5 2.3 1 1 1 2 2 2 1 Tho complex subunit 7 CCDC92 PF14916.6 EGD86810.1 - 0.0023 17.6 0.2 0.0071 16.1 0.2 1.8 1 0 0 1 1 1 1 Coiled-coil domain of unknown function DUF1843 PF08898.10 EGD86810.1 - 0.0093 16.4 2.6 0.032 14.7 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1843) Peroxin-13_N PF04088.13 EGD86810.1 - 0.017 15.4 0.3 0.042 14.1 0.3 1.7 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FUSC PF04632.12 EGD86810.1 - 0.066 11.7 6.7 0.089 11.3 6.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fer4_NifH PF00142.18 EGD86810.1 - 0.17 11.3 0.5 0.26 10.7 0.5 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1664 PF07889.12 EGD86810.1 - 0.21 11.6 1.1 0.49 10.4 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Mod_r PF07200.13 EGD86810.1 - 0.28 11.3 17.3 1.3 9.1 17.3 2.0 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein LMBR1 PF04791.16 EGD86810.1 - 1 8.2 7.4 1.4 7.8 7.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 EGD86810.1 - 8.9 5.6 13.9 1.5e+02 1.5 13.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TBCA PF02970.16 EGD86811.1 - 1.4e-24 86.3 13.5 1.5e-24 86.1 13.1 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A HAUS5 PF14817.6 EGD86811.1 - 0.012 14.4 8.8 0.015 14.1 8.8 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 AdoMet_Synthase PF01941.19 EGD86811.1 - 0.017 13.9 0.2 0.028 13.2 0.1 1.4 1 1 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) FIVAR PF07554.13 EGD86811.1 - 0.15 12.8 4.7 0.43 11.4 4.7 2.0 1 1 0 1 1 1 0 FIVAR domain Exonuc_VII_L PF02601.15 EGD86811.1 - 0.16 11.5 6.7 0.18 11.4 6.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.11 EGD86811.1 - 0.3 11.3 2.4 0.19 12.0 0.6 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HSP70 PF00012.20 EGD86811.1 - 0.51 8.5 9.6 0.58 8.3 9.6 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF2570 PF10828.8 EGD86811.1 - 1.1 9.1 6.5 1.6 8.6 6.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Tho2 PF11262.8 EGD86811.1 - 3 6.9 8.7 3.6 6.7 8.7 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 V_ATPase_I PF01496.19 EGD86811.1 - 5.3 4.8 7.3 5.8 4.7 7.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Band_7 PF01145.25 EGD86813.1 - 7.1e-16 58.7 0.0 7.1e-16 58.7 0.0 2.4 2 1 0 2 2 2 1 SPFH domain / Band 7 family F-box_4 PF15966.5 EGD86815.1 - 5e-05 23.2 0.2 0.00011 22.0 0.2 1.5 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 EGD86815.1 - 0.0023 17.8 1.0 0.0023 17.8 1.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGD86815.1 - 0.0089 15.9 2.3 0.024 14.5 2.3 1.7 1 0 0 1 1 1 1 F-box domain HNH_2 PF13391.6 EGD86817.1 - 0.00065 19.8 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease PhnA_Zn_Ribbon PF08274.12 EGD86817.1 - 0.097 12.6 0.5 0.18 11.8 0.5 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Stc1 PF12898.7 EGD86818.1 - 0.017 15.7 1.6 0.37 11.4 0.5 2.5 2 0 0 2 2 2 0 Stc1 domain F-box-like PF12937.7 EGD86818.1 - 0.12 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 F-box-like Sfi1 PF08457.10 EGD86820.1 - 3.7e-196 653.1 91.3 6.2e-195 649.0 81.2 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein p450 PF00067.22 EGD86821.2 - 1.5e-63 215.2 0.0 2.3e-63 214.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EGD86821.2 - 6.5e-27 94.6 0.0 1.1e-26 93.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGD86821.2 - 2.8e-21 76.2 0.0 6.2e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGD86821.2 - 1.5e-11 44.9 0.0 3.6e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EGD86821.2 - 0.0012 19.1 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.12 EGD86821.2 - 0.085 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain tRNA-synt_1 PF00133.22 EGD86822.1 - 5.8e-223 741.5 0.0 8e-223 741.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGD86822.1 - 2.6e-24 85.9 0.0 9.6e-24 84.1 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGD86822.1 - 3.6e-13 49.0 0.0 7.3e-06 25.0 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGD86822.1 - 0.075 12.4 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain gp45-slide_C PF09116.10 EGD86822.1 - 0.078 13.0 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal Uso1_p115_head PF04869.14 EGD86823.1 - 4.7e-111 370.9 0.1 3.9e-110 367.9 0.0 2.5 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EGD86823.1 - 2.5e-18 66.7 32.4 2.5e-18 66.7 32.4 3.4 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2570 PF10828.8 EGD86823.1 - 0.71 9.7 31.2 0.078 12.8 7.5 3.9 2 1 1 4 4 4 0 Protein of unknown function (DUF2570) Filament PF00038.21 EGD86823.1 - 1.2 8.7 50.7 2.8 7.5 50.6 1.6 1 1 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 EGD86823.1 - 6.1 5.6 51.3 0.73 8.7 23.5 2.8 1 1 0 2 2 2 0 Spc7 kinetochore protein XRN_M PF17846.1 EGD86824.2 - 1.5e-153 511.9 0.1 3.5e-153 510.7 0.1 1.5 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EGD86824.2 - 5.4e-17 62.0 4.1 9.6e-17 61.2 0.0 2.7 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus Myc_N PF01056.18 EGD86824.2 - 0.39 10.6 3.5 0.62 9.9 3.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region EPSP_synthase PF00275.20 EGD86825.2 - 2.4e-129 431.7 0.0 3.9e-129 431.0 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHquinase_I PF01487.15 EGD86825.2 - 3.3e-57 194.4 0.0 6.3e-57 193.5 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EGD86825.2 - 9.5e-37 126.6 0.0 1.7e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.11 EGD86825.2 - 1.8e-26 92.2 0.0 5e-26 90.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EGD86825.2 - 8.3e-07 28.7 2.0 1.6e-06 27.8 0.6 2.2 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EGD86825.2 - 4.4e-05 23.6 0.0 0.00012 22.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DHQ_synthase PF01761.20 EGD86825.2 - 0.00025 20.3 0.0 0.0006 19.1 0.0 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase AAA_24 PF13479.6 EGD86825.2 - 0.0015 18.3 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGD86825.2 - 0.053 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PPR_2 PF13041.6 EGD86826.1 - 2e-24 85.5 0.0 9.9e-17 60.9 0.0 3.0 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 EGD86826.1 - 4.4e-09 36.3 0.0 0.00043 20.3 0.0 2.7 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGD86826.1 - 1.1e-06 28.2 0.0 0.35 10.6 0.0 3.7 3 0 0 3 3 3 3 PPR repeat PPR PF01535.20 EGD86826.1 - 9.7e-05 22.4 4.1 0.0019 18.3 0.0 4.2 4 1 0 4 4 4 1 PPR repeat PPR_long PF17177.4 EGD86826.1 - 0.011 15.1 0.0 0.045 13.1 0.0 1.9 1 1 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Complex1_LYR PF05347.15 EGD86826.1 - 3.7 7.7 5.9 13 5.9 0.1 3.3 3 0 0 3 3 3 0 Complex 1 protein (LYR family) DEAD PF00270.29 EGD86827.1 - 2.8e-50 170.5 0.0 6.3e-49 166.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD86827.1 - 1e-29 103.1 0.1 3.9e-29 101.2 0.0 1.9 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD86827.1 - 9.9e-05 22.4 0.0 0.00033 20.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EGD86827.1 - 0.013 15.7 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_19 PF13245.6 EGD86827.1 - 0.022 15.1 0.0 3.9 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF5335 PF17269.2 EGD86827.1 - 0.032 14.1 0.1 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) CMS1 PF14617.6 EGD86827.1 - 0.041 13.2 0.8 1.9 7.8 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF2443 PF10398.9 EGD86827.1 - 0.12 12.4 0.4 0.27 11.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) AAA_22 PF13401.6 EGD86827.1 - 0.41 10.9 1.9 20 5.5 0.0 3.2 3 1 1 4 4 4 0 AAA domain TENA_THI-4 PF03070.16 EGD86828.2 - 3e-52 177.5 0.5 4.6e-52 176.9 0.5 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Phos_pyr_kin PF08543.12 EGD86828.2 - 4.3e-41 140.9 0.1 6.3e-41 140.4 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EGD86828.2 - 3.5e-05 23.3 0.3 0.00039 19.8 0.3 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 EGD86828.2 - 0.017 14.6 0.1 0.039 13.3 0.1 1.5 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Paramyxo_C PF01692.18 EGD86829.2 - 0.032 13.6 0.2 0.048 13.0 0.2 1.2 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C Sds3 PF08598.11 EGD86837.2 - 3.4e-10 40.3 2.9 1.3e-07 31.9 2.9 2.2 1 1 0 1 1 1 1 Sds3-like DUF908 PF06012.12 EGD86837.2 - 0.11 11.9 2.9 0.14 11.5 2.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PilO PF04350.13 EGD86844.1 - 0.015 15.5 1.1 0.038 14.1 0.3 2.0 1 1 1 2 2 2 0 Pilus assembly protein, PilO Baculo_PEP_C PF04513.12 EGD86844.1 - 0.019 15.0 0.7 0.019 15.0 0.7 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med3 PF11593.8 EGD86844.1 - 0.027 13.7 14.2 0.021 14.1 7.7 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal CaiF_GrlA PF07180.11 EGD86844.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 CaiF/GrlA transcriptional regulator DUF2752 PF10825.8 EGD86844.1 - 0.29 11.2 1.1 0.49 10.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) DUF148 PF02520.17 EGD86844.1 - 2.8 8.1 6.9 0.21 11.7 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 RCC1 PF00415.18 EGD86845.2 - 2.8e-16 59.9 1.0 7.6e-06 26.5 0.0 3.8 4 1 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGD86845.2 - 1.5e-09 37.4 9.9 8.1e-05 22.3 0.2 2.9 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat p450 PF00067.22 EGD86846.1 - 4.9e-28 98.1 0.0 7.1e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Sterol_MT_C PF08498.10 EGD86847.1 - 2.5e-23 82.2 0.1 4.6e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EGD86847.1 - 2.8e-19 69.5 0.0 5e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD86847.1 - 5.6e-18 65.4 0.0 1.1e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD86847.1 - 1.8e-17 63.5 0.0 2.6e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD86847.1 - 1.2e-13 51.0 0.0 2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGD86847.1 - 4.9e-12 45.7 0.1 6.6e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGD86847.1 - 6e-12 45.7 0.0 9.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD86847.1 - 1.6e-10 41.6 0.0 3.6e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGD86847.1 - 1.1e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EGD86847.1 - 0.0009 18.7 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGD86847.1 - 0.0051 16.4 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EGD86847.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) MetW PF07021.12 EGD86847.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DRE2_N PF16803.5 EGD86847.1 - 0.028 14.7 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus BTB PF00651.31 EGD86848.2 - 2e-06 28.0 0.0 7.6e-06 26.1 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain Peptidase_S24 PF00717.23 EGD86849.1 - 3.3e-08 33.4 0.0 5.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Pro-rich_19 PF15455.6 EGD86850.1 - 0.12 11.5 2.7 0.11 11.6 1.7 1.3 1 1 0 1 1 1 0 Proline-rich 19 Menin PF05053.13 EGD86850.1 - 0.21 9.9 9.3 0.28 9.5 9.3 1.1 1 0 0 1 1 1 0 Menin CSG2 PF16965.5 EGD86850.1 - 0.28 10.1 4.1 0.4 9.6 4.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4770 PF15994.5 EGD86850.1 - 1.5 9.0 6.2 6.7 6.9 5.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4770) Macoilin PF09726.9 EGD86850.1 - 5.3 5.5 13.2 6.3 5.2 13.2 1.0 1 0 0 1 1 1 0 Macoilin family UQ_con PF00179.26 EGD86852.1 - 1.6e-42 144.5 0.0 1.8e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGD86852.1 - 4.1e-07 29.8 0.0 5.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGD86852.1 - 0.03 14.2 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 EGD86852.1 - 0.1 12.9 0.1 0.19 12.0 0.1 1.6 1 1 0 1 1 1 0 RWD domain RabGAP-TBC PF00566.18 EGD86855.2 - 5.8e-34 117.6 0.8 1.3e-32 113.2 0.2 3.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF4927 PF16279.5 EGD86855.2 - 0.054 14.5 0.2 2.8 9.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4927) BCS1_N PF08740.11 EGD86857.1 - 9.6e-49 165.9 0.6 1.5e-48 165.3 0.6 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGD86857.1 - 2.3e-18 66.9 0.0 4.6e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGD86857.1 - 8.9e-06 26.2 0.1 3e-05 24.5 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EGD86857.1 - 0.00034 19.9 0.0 0.00073 18.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EGD86857.1 - 0.0063 16.7 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGD86857.1 - 0.011 16.0 0.0 0.087 13.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 EGD86857.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EGD86857.1 - 0.013 15.5 0.0 0.034 14.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EGD86857.1 - 0.016 15.0 0.0 0.06 13.1 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.6 EGD86857.1 - 0.029 14.2 0.0 0.069 12.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGD86857.1 - 0.039 14.4 0.0 0.12 12.7 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.27 EGD86857.1 - 0.042 14.4 0.0 0.083 13.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EGD86857.1 - 0.045 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGD86857.1 - 0.11 11.9 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 EGD86857.1 - 0.13 12.1 0.0 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EGD86857.1 - 0.13 11.9 0.0 0.48 10.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGD86857.1 - 0.2 11.6 0.0 0.58 10.1 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain Lactamase_B_2 PF12706.7 EGD86858.1 - 1.3e-11 44.4 0.0 1.5e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGD86858.1 - 2e-09 37.5 0.0 7.8e-09 35.6 0.0 1.9 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Cpn60_TCP1 PF00118.24 EGD86859.1 - 1.3e-173 578.2 1.5 1.5e-173 578.0 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.12 EGD86860.1 - 7.1e-40 136.0 16.2 1e-39 135.4 16.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 EGD86860.1 - 0.0049 16.0 0.0 0.0071 15.5 0.0 1.1 1 0 0 1 1 1 1 Lyase, catalytic Orbi_VP6 PF01516.16 EGD86860.1 - 0.061 12.8 12.9 0.084 12.4 12.9 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 PPL5 PF18168.1 EGD86860.1 - 0.25 10.6 3.5 0.32 10.3 3.5 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S49_N PF08496.10 EGD86860.1 - 2.6 8.1 9.4 4.1 7.4 9.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ERK-JNK_inhib PF15002.6 EGD86860.1 - 3.4 7.3 13.1 5 6.8 13.1 1.2 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor zf-PARP PF00645.18 EGD86861.1 - 2.8e-22 79.3 0.4 2.8e-22 79.3 0.4 3.9 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Kinesin PF00225.23 EGD86862.2 - 2.2e-19 69.6 0.0 2.5e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain TPR_14 PF13428.6 EGD86863.2 - 0.1 13.5 6.8 1.7 9.6 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 EGD86864.2 - 5e-66 223.3 0.1 9e-66 222.5 0.0 1.5 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_1 PF00515.28 EGD86864.2 - 0.00011 21.8 0.2 4.3 7.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGD86864.2 - 0.00019 21.3 0.3 0.55 10.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGD86864.2 - 0.00086 19.9 0.3 0.4 11.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGD86864.2 - 0.0014 18.7 0.2 0.36 11.0 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat CDC45 PF02724.14 EGD86864.2 - 0.006 14.9 5.9 0.007 14.7 5.9 1.1 1 0 0 1 1 1 1 CDC45-like protein TPR_12 PF13424.6 EGD86864.2 - 0.022 15.0 0.7 0.56 10.5 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Nop14 PF04147.12 EGD86864.2 - 0.11 10.7 11.1 0.14 10.3 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.6 EGD86864.2 - 0.11 12.8 9.7 0.11 12.9 7.5 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 EGD86864.2 - 0.25 10.6 11.5 0.53 9.6 11.5 1.5 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 EGD86864.2 - 0.4 10.0 11.9 0.54 9.6 11.9 1.1 1 0 0 1 1 1 0 SDA1 ANAPC3 PF12895.7 EGD86864.2 - 0.57 10.5 3.3 1 9.6 0.2 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RRN3 PF05327.11 EGD86864.2 - 1.5 7.2 7.7 2.4 6.6 7.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Exo5 PF09810.9 EGD86866.1 - 8.9e-125 417.0 0.0 1.2e-124 416.5 0.0 1.2 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EGD86866.1 - 0.02 14.8 0.2 5.4 6.8 0.0 2.9 4 0 0 4 4 4 0 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.12 EGD86867.2 - 5.1e-14 52.3 0.4 5.1e-14 52.3 0.4 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family Histone PF00125.24 EGD86868.1 - 2.5e-49 167.0 3.3 2.8e-49 166.8 3.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGD86868.1 - 5.3e-06 26.7 0.0 8.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGD86868.1 - 6e-05 23.1 0.7 8.5e-05 22.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EGD86868.1 - 0.0013 19.4 1.2 0.0015 19.1 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EGD86868.1 - 0.0077 16.5 0.2 0.025 14.9 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EGD86868.1 - 0.025 14.6 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 EGD86868.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 EGD86869.2 - 1.9e-08 34.4 0.1 2.4e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EGD86869.2 - 4.2e-05 23.9 0.1 4.8e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EGD86869.2 - 0.00013 22.0 0.1 0.00019 21.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGD86869.2 - 0.0006 20.1 0.1 0.00079 19.8 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGD86869.2 - 0.00064 20.0 0.0 0.0012 19.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGD86869.2 - 0.0098 16.0 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGD86869.2 - 0.057 13.4 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated zf-C2H2 PF00096.26 EGD86876.1 - 1.3e-05 25.4 29.1 0.00015 22.0 1.4 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD86876.1 - 0.01 16.6 25.2 0.029 15.2 1.1 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGD86876.1 - 1.5 9.4 11.1 13 6.4 0.0 3.9 3 0 0 3 3 3 0 Zinc-finger double domain Glyco_transf_22 PF03901.17 EGD86877.1 - 3e-86 290.3 17.0 3.5e-86 290.1 17.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HET PF06985.11 EGD86878.1 - 2.2e-11 44.3 0.0 4.4e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Gar1 PF04410.14 EGD86879.1 - 5.4e-45 152.9 0.1 1.2e-44 151.8 0.1 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region YL1 PF05764.13 EGD86879.1 - 6.5 6.8 11.2 20 5.2 5.5 2.2 2 0 0 2 2 2 0 YL1 nuclear protein AF-4 PF05110.13 EGD86879.1 - 9 4.2 8.3 12 3.9 8.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RRM_1 PF00076.22 EGD86881.2 - 5.2e-06 26.2 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_28 PF02636.17 EGD86885.2 - 2.5e-82 276.4 0.0 3.2e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rhodanese PF00581.20 EGD86886.1 - 2.3e-09 37.7 0.0 2.9e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_S21 PF01165.20 EGD86887.1 - 3.1e-07 30.0 1.0 4.1e-07 29.6 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein S21 PGI PF00342.19 EGD86889.1 - 6.2e-241 800.1 2.6 7.1e-241 799.9 2.6 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Urease_beta PF00699.20 EGD86889.1 - 0.02 14.9 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Urease beta subunit PUD1_2 PF18457.1 EGD86891.1 - 7.8e-46 156.2 0.8 9e-46 156.0 0.8 1.0 1 0 0 1 1 1 1 Up-Regulated in long-lived daf-2 PWI PF01480.17 EGD86892.1 - 5.8e-17 61.8 0.7 1.5e-16 60.4 0.7 1.8 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EGD86892.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_5 PF00266.19 EGD86893.1 - 1e-25 90.5 0.0 1.8e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V TIM21 PF08294.11 EGD86896.1 - 6.9e-39 133.0 0.0 8.7e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 EGD86896.1 - 1.4e-05 24.8 0.0 3.2e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.18 EGD86897.1 - 8.5e-35 119.4 0.5 1.5e-34 118.5 0.5 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pterin_bind PF00809.22 EGD86898.1 - 8.6e-80 267.9 0.2 1.1e-79 267.5 0.2 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EGD86898.1 - 1.7e-35 121.9 0.0 3.9e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.15 EGD86899.1 - 1.2e-56 192.5 1.2 1.7e-56 192.1 1.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGD86899.1 - 9.1e-11 41.3 0.6 2.3e-09 36.7 0.6 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGD86899.1 - 1.2e-07 31.1 2.0 1.9e-07 30.5 2.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EGD86899.1 - 0.0023 17.2 0.2 0.0034 16.6 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 EGD86899.1 - 0.0032 16.7 0.2 0.0049 16.1 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase eIF3g PF12353.8 EGD86900.2 - 3.3e-45 153.5 1.8 3.3e-45 153.5 1.8 1.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EGD86900.2 - 1.5e-16 59.9 0.0 2.4e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 EGD86900.2 - 0.014 15.7 0.1 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 TackOD1 PF18551.1 EGD86900.2 - 0.049 13.3 0.1 0.084 12.5 0.1 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 RRM_occluded PF16842.5 EGD86900.2 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif NDT80_PhoG PF05224.12 EGD86902.2 - 2.6e-41 141.9 0.0 3.7e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Methyltransf_16 PF10294.9 EGD86907.1 - 7.2e-09 35.6 0.1 0.00085 19.1 0.0 2.4 2 1 0 2 2 2 2 Lysine methyltransferase MIF4G PF02854.19 EGD86908.2 - 7.2e-53 179.4 0.0 1.1e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EGD86908.2 - 7.9e-25 86.8 2.1 2.1e-24 85.4 2.1 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Borrelia_P83 PF05262.11 EGD86909.1 - 0.56 8.6 24.0 0.68 8.4 24.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 EGD86909.1 - 3 7.1 8.1 3.8 6.8 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TB2_DP1_HVA22 PF03134.19 EGD86910.1 - 3e-23 81.5 9.1 4.5e-23 81.0 9.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family F-box-like PF12937.7 EGD86911.1 - 0.00021 21.1 0.3 0.00046 20.0 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD86911.1 - 0.0021 17.9 0.5 0.005 16.7 0.5 1.6 1 0 0 1 1 1 1 F-box domain TraC_F_IV PF11130.8 EGD86913.1 - 0.028 14.1 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer APOBEC_C PF05240.14 EGD86913.1 - 0.05 13.6 0.3 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 APOBEC-like C-terminal domain NAD1 PF18778.1 EGD86913.1 - 0.079 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Sarcolipin PF05366.11 EGD86914.1 - 0.58 9.9 2.5 1 9.1 2.5 1.3 1 0 0 1 1 1 0 Sarcolipin PHO4 PF01384.20 EGD86917.1 - 4.1e-99 331.8 18.2 4.7e-99 331.6 18.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 EGD86917.1 - 0.96 9.8 9.1 1.6 9.1 0.3 2.8 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 MFS_1 PF07690.16 EGD86920.2 - 1.7e-05 23.9 59.2 0.00023 20.2 54.6 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD86920.2 - 0.0011 18.0 12.0 0.0011 18.0 12.0 3.3 3 0 0 3 3 3 3 Sugar (and other) transporter UxuA PF03786.13 EGD86920.2 - 0.062 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) TANGO2 PF05742.12 EGD86921.2 - 1.4e-74 251.4 0.0 1.6e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 BPL_LplA_LipB PF03099.19 EGD86922.2 - 4e-11 42.9 0.0 6.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EGD86922.2 - 5.6e-06 26.2 0.0 8.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain zf-RING_2 PF13639.6 EGD86923.1 - 1.2e-13 51.2 5.4 2.5e-13 50.1 5.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGD86923.1 - 1.6e-10 40.5 1.6 2.8e-10 39.7 1.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGD86923.1 - 1.1e-08 34.8 5.0 1.1e-08 34.8 5.0 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGD86923.1 - 9.2e-08 31.8 2.1 9.2e-08 31.8 2.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGD86923.1 - 1.1e-06 28.8 6.1 5.4e-06 26.6 6.1 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGD86923.1 - 6.2e-06 26.0 6.6 0.00011 22.0 6.3 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGD86923.1 - 2.2e-05 24.3 1.7 5.3e-05 23.1 1.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGD86923.1 - 0.00011 22.0 1.9 0.00011 22.0 1.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD86923.1 - 0.00016 21.6 4.0 0.00016 21.6 4.0 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGD86923.1 - 0.00033 20.6 1.5 0.00069 19.6 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGD86923.1 - 0.021 14.6 2.9 0.021 14.6 2.9 1.7 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGD86923.1 - 0.15 11.7 1.2 0.28 10.9 1.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 EGD86923.1 - 0.16 11.9 3.8 0.28 11.1 1.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 EGD86923.1 - 0.58 10.1 2.7 1.3 9.0 2.7 1.7 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 EGD86923.1 - 0.63 10.2 5.1 1.5 9.0 5.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EGD86923.1 - 1.3 9.2 5.7 3.8 7.8 4.1 2.5 2 1 0 2 2 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EGD86923.1 - 8.5 6.8 8.2 0.17 12.2 1.1 2.0 2 0 0 2 2 1 0 RING-like domain NLPC_P60 PF00877.19 EGD86925.2 - 8.8e-09 35.3 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family Phage_lysozyme PF00959.19 EGD86926.1 - 6.8e-08 32.9 0.0 1e-07 32.4 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme Stanniocalcin PF03298.13 EGD86927.1 - 4.6e-06 26.1 0.0 6.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Stanniocalcin family MS_channel PF00924.18 EGD86928.2 - 6.6e-19 68.3 0.5 1.2e-18 67.4 0.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EGD86928.2 - 0.092 12.3 0.2 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EGD86928.2 - 0.12 12.9 0.1 0.43 11.1 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain pair Pkinase PF00069.25 EGD86930.1 - 6e-26 91.4 0.0 8.9e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD86930.1 - 1.5e-06 27.7 0.0 2.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGD86930.1 - 0.00096 18.6 0.1 0.0014 18.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGD86930.1 - 0.0057 16.6 0.0 0.016 15.1 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Aminotran_1_2 PF00155.21 EGD86933.1 - 6e-79 265.8 0.0 7.2e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.9 EGD86935.1 - 8.8e-10 38.7 0.3 5.6e-09 36.1 0.0 2.4 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 EGD86935.1 - 8.2e-06 25.7 0.3 2.5e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 SNARE domain DUF1897 PF09005.10 EGD86935.1 - 5.9 6.5 5.9 20 4.8 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) APG6_N PF17675.1 EGD86935.1 - 6.5 7.3 9.3 5.7 7.5 1.9 3.1 3 1 0 3 3 3 0 Apg6 coiled-coil region TPR_1 PF00515.28 EGD86936.2 - 5.8e-14 51.2 6.9 3.1e-07 29.9 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGD86936.2 - 9.6e-14 50.3 5.6 1.5e-05 24.8 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGD86936.2 - 4.9e-10 39.6 0.2 1.2e-05 25.5 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.24 EGD86936.2 - 6.9e-07 29.1 0.2 1.3e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.6 EGD86936.2 - 9.2e-07 28.5 0.7 0.00028 20.7 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGD86936.2 - 2.1e-06 27.3 3.9 7.9e-05 22.3 0.8 3.6 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 EGD86936.2 - 7.9e-06 25.7 6.3 0.0012 18.8 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGD86936.2 - 3.4e-05 24.2 0.2 8.3 7.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGD86936.2 - 9.4e-05 23.0 1.5 0.034 14.8 0.5 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGD86936.2 - 0.0013 18.8 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGD86936.2 - 0.0061 16.9 0.2 0.36 11.3 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGD86936.2 - 0.0087 16.8 0.4 0.28 12.1 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGD86936.2 - 0.29 11.1 3.4 1 9.3 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat AMP-binding PF00501.28 EGD86940.1 - 1e-214 712.9 0.0 3.9e-75 253.1 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EGD86940.1 - 2e-124 415.8 0.0 4.8e-46 157.4 0.0 5.6 5 1 0 5 5 5 4 Condensation domain PP-binding PF00550.25 EGD86940.1 - 8e-38 128.6 0.5 2.1e-11 44.0 0.0 4.7 4 0 0 4 4 4 3 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 EGD86940.1 - 1.3e-33 116.2 0.0 3e-33 115.1 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGD86940.1 - 3.5e-09 36.5 0.0 7.4e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 EGD86940.1 - 0.00018 22.4 0.0 3 8.9 0.0 3.8 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EGD86940.1 - 0.072 11.7 0.0 0.33 9.6 0.0 1.9 2 0 0 2 2 2 0 Transferase family Usp PF00582.26 EGD86942.1 - 1.8e-22 80.4 0.1 3.4e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Universal stress protein family Med27 PF11571.8 EGD86943.1 - 1e-20 73.9 0.5 2.4e-20 72.7 0.5 1.7 1 0 0 1 1 1 1 Mediator complex subunit 27 SpoIIIAH PF12685.7 EGD86945.1 - 0.0014 18.5 1.1 0.0018 18.2 1.1 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein Presenilin PF01080.17 EGD86945.1 - 0.049 12.4 0.4 0.066 12.0 0.4 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 EGD86945.1 - 0.059 14.3 0.9 0.15 13.0 0.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF1180 PF06679.12 EGD86945.1 - 0.13 12.6 1.7 0.27 11.6 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Macoilin PF09726.9 EGD86945.1 - 0.33 9.5 5.0 0.36 9.3 5.0 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 EGD86945.1 - 1.5 7.9 4.2 1.7 7.8 4.2 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter DUF4614 PF15391.6 EGD86945.1 - 1.7 8.6 10.0 2.9 7.9 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) NPR3 PF03666.13 EGD86945.1 - 2.1 7.0 6.0 3 6.5 6.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 EGD86945.1 - 6.2 5.5 12.8 8.7 5.1 12.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SNF2_N PF00176.23 EGD86946.1 - 9.6e-67 225.2 0.0 1.6e-66 224.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGD86946.1 - 6.3e-18 65.1 0.0 1.5e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD86946.1 - 8.4e-06 25.9 0.0 2.2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIF_beta PF02270.15 EGD86946.1 - 0.0011 19.1 0.1 0.01 16.0 0.0 2.5 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain SPEG_u2 PF16650.5 EGD86946.1 - 0.0064 16.6 0.3 0.0064 16.6 0.3 2.0 2 0 0 2 2 2 1 Unstructured region on SPEG complex protein AAA_11 PF13086.6 EGD86946.1 - 3.7 7.3 0.0 3.7 7.3 0.0 3.6 4 0 0 4 4 4 0 AAA domain Pkinase PF00069.25 EGD86947.2 - 1.3e-07 31.3 0.0 1e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain TAF4 PF05236.14 EGD86947.2 - 1.5 8.5 7.6 2.5 7.8 7.6 1.6 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Rotamase_2 PF13145.6 EGD86947.2 - 4.7 8.1 12.7 2.8 8.8 5.6 2.7 3 0 0 3 3 3 0 PPIC-type PPIASE domain eIF-3c_N PF05470.12 EGD86948.2 - 4.5e-84 282.9 2.2 6.9e-84 282.2 2.2 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EGD86948.2 - 3.4e-13 50.0 0.6 5.2e-12 46.2 0.1 2.3 1 1 1 2 2 2 1 PCI domain DUF1385 PF07136.11 EGD86948.2 - 0.029 13.7 0.0 0.089 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) Sigma70_r4 PF04545.16 EGD86948.2 - 0.084 12.4 0.1 0.44 10.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 GRP PF07172.11 EGD86948.2 - 0.72 10.6 21.0 1.3 9.7 21.0 1.4 1 0 0 1 1 1 0 Glycine rich protein family EAP30 PF04157.16 EGD86949.1 - 2.4e-71 239.8 0.0 2.7e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_L30_N PF08079.12 EGD86950.2 - 1.2e-26 92.7 14.5 1.2e-26 92.7 14.5 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EGD86950.2 - 2.1e-17 62.7 1.7 2.1e-17 62.7 1.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_pol_B_exo1 PF03104.19 EGD86951.2 - 6.6e-46 157.0 0.0 9.4e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EGD86951.2 - 6.8e-30 104.2 0.1 2.9e-29 102.1 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_2 PF03175.13 EGD86951.2 - 0.00028 19.9 0.0 0.00045 19.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral HSP70 PF00012.20 EGD86952.1 - 8e-264 876.4 16.0 9.1e-264 876.2 16.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGD86952.1 - 9.9e-15 54.2 6.7 6.3e-13 48.2 2.5 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EGD86952.1 - 0.00011 22.0 0.0 0.0003 20.6 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 EGD86952.1 - 0.046 12.9 6.5 0.1 11.8 0.2 3.2 3 1 1 4 4 4 0 StbA protein DUF1464 PF07318.12 EGD86952.1 - 0.062 12.5 1.2 0.66 9.1 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1464) Scaffolding_pro PF11418.8 EGD86952.1 - 0.1 13.2 0.8 0.26 11.8 0.8 1.6 1 0 0 1 1 1 0 Phi29 scaffolding protein SMBP PF16785.5 EGD86952.1 - 0.15 12.2 4.1 0.14 12.4 1.2 2.3 2 0 0 2 2 2 0 Small metal-binding protein FtsA PF14450.6 EGD86952.1 - 3.7 8.0 12.4 1.3 9.4 0.9 3.9 3 3 0 3 3 3 0 Cell division protein FtsA DUF2415 PF10313.9 EGD86953.1 - 9.6e-16 57.4 0.0 2.5e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Mersacidin PF16934.5 EGD86953.1 - 0.2 11.4 0.1 0.43 10.4 0.1 1.5 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) PRIMA1 PF16101.5 EGD86953.1 - 2.1 8.4 6.5 5.1 7.1 6.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EGD86953.1 - 2.9 7.3 8.9 5.7 6.3 8.9 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cse1 PF08506.10 EGD86956.2 - 8.2e-07 28.2 0.0 2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 EGD86956.2 - 0.0046 15.5 0.5 0.011 14.2 0.1 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus RTP1_C1 PF10363.9 EGD86956.2 - 0.021 15.0 0.1 0.082 13.1 0.1 2.1 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Telomere_reg-2 PF10193.9 EGD86956.2 - 0.043 14.2 0.6 0.31 11.5 0.1 2.6 2 0 0 2 2 2 0 Telomere length regulation protein HEAT_EZ PF13513.6 EGD86956.2 - 0.046 14.2 1.5 16 6.1 0.1 4.6 4 1 1 5 5 5 0 HEAT-like repeat DUF2408 PF10303.9 EGD86956.2 - 0.07 13.7 0.1 0.97 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) HEAT_2 PF13646.6 EGD86956.2 - 0.082 13.3 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 HEAT repeats Vac14_Fab1_bd PF12755.7 EGD86956.2 - 0.1 13.2 2.6 0.95 10.1 0.0 3.6 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGD86956.2 - 0.16 12.0 0.5 0.59 10.2 0.0 2.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CENP-F_N PF10481.9 EGD86958.1 - 0.26 10.9 7.1 0.86 9.2 6.5 2.1 1 1 1 2 2 2 0 Cenp-F N-terminal domain DegS PF05384.11 EGD86958.1 - 3.3 7.2 9.1 0.74 9.3 5.1 1.8 2 0 0 2 2 2 0 Sensor protein DegS FlaC_arch PF05377.11 EGD86958.1 - 3.4 8.1 4.5 3.1 8.2 0.3 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 EGD86958.1 - 3.9 7.8 4.7 0.88 9.9 0.5 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1168 PF06658.12 EGD86959.2 - 2.2 8.1 22.9 0.11 12.3 16.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Peptidase_S49_N PF08496.10 EGD86959.2 - 9.4 6.3 9.0 16 5.5 9.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF501 PF04417.12 EGD86959.2 - 9.7 6.0 8.0 26 4.6 7.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF501) DbpA PF03880.15 EGD86960.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_1 PF00076.22 EGD86960.1 - 0.038 13.8 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 EGD86962.1 - 1.6e-31 109.5 27.3 2e-30 105.9 12.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD86962.1 - 2.4e-08 33.3 6.5 2.4e-08 33.3 6.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Fungal_TACC PF12709.7 EGD86963.1 - 2.6e-10 40.6 20.9 2.2e-08 34.4 2.9 4.2 3 1 2 5 5 5 2 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1664 PF07889.12 EGD86963.1 - 0.051 13.6 17.8 0.098 12.7 4.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 EGD86963.1 - 0.16 11.6 29.0 0.017 14.8 13.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF745) AAA_13 PF13166.6 EGD86963.1 - 0.2 10.3 21.6 0.18 10.4 6.3 2.4 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.6 EGD86963.1 - 0.51 9.6 27.8 0.33 10.3 7.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2959 PF11172.8 EGD86963.1 - 1 9.5 16.1 0.83 9.8 10.6 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2959) GAS PF13851.6 EGD86963.1 - 1.5 8.1 32.0 0.14 11.5 11.3 3.0 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 EGD86963.1 - 1.9 8.7 12.2 2.9 8.1 0.3 3.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3209 PF11483.8 EGD86963.1 - 2.8 8.4 12.3 6.8 7.2 2.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3209) Z1 PF10593.9 EGD86963.1 - 5 6.6 9.1 9.2 5.7 1.0 2.6 2 1 0 2 2 2 0 Z1 domain ADIP PF11559.8 EGD86963.1 - 6.3 6.9 31.3 1.1 9.3 2.9 4.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding FAD_binding_3 PF01494.19 EGD86964.1 - 7.6e-13 48.4 0.1 2.1e-12 47.0 0.0 1.8 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EGD86964.1 - 6.7e-06 25.4 0.4 0.14 11.2 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 EGD86964.1 - 0.0013 18.4 0.1 0.004 16.8 0.1 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGD86964.1 - 0.0041 17.3 0.2 0.077 13.2 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGD86964.1 - 0.012 15.6 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding SE PF08491.10 EGD86964.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase DegT_DnrJ_EryC1 PF01041.17 EGD86964.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.18 EGD86967.2 - 4.9e-27 94.6 0.4 8e-27 93.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EGD86968.1 - 8.8e-15 54.5 31.5 8.8e-15 54.5 31.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGD86968.1 - 7.8e-12 45.2 4.7 3.4e-11 43.1 4.7 2.1 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF4149 PF13664.6 EGD86968.1 - 6.7 7.1 10.5 12 6.2 7.6 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Amidohydro_1 PF01979.20 EGD86969.1 - 1.1e-17 64.4 0.0 6.2e-17 61.9 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGD86969.1 - 1.6e-12 47.7 0.5 5.9e-09 35.9 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Aldedh PF00171.22 EGD86971.1 - 1e-158 528.7 0.3 1.2e-158 528.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 EGD86971.1 - 0.014 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 WTAP/Mum2p family Glucosamine_iso PF01182.20 EGD86972.2 - 1.1e-22 81.0 0.0 1.7e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.21 EGD86973.1 - 6.8e-68 229.4 0.0 1e-67 228.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EGD86973.1 - 5.2e-07 29.8 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.25 EGD86973.1 - 1e-05 25.8 0.0 2.9e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGD86973.1 - 0.041 13.8 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_7 PF13508.7 EGD86973.1 - 0.046 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGD86973.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.12 EGD86974.1 - 7.4e-34 117.6 1.0 5.4e-33 114.8 0.0 2.6 3 0 0 3 3 3 1 NDT80 / PhoG like DNA-binding family DUF3013 PF11217.8 EGD86974.1 - 0.081 12.8 0.1 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3013) TFIIA PF03153.13 EGD86974.1 - 1.3 9.0 31.0 2.1 8.2 11.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hexokinase_1 PF00349.21 EGD86975.2 - 5.3e-46 157.0 0.0 8.7e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EGD86975.2 - 5.3e-43 147.2 0.0 9.6e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Hexokinase p450 PF00067.22 EGD86977.1 - 1.7e-58 198.5 0.0 2.1e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Emaravirus_P4 PF16505.5 EGD86977.1 - 0.22 10.5 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily TRP PF06011.12 EGD86979.1 - 5.2e-140 466.9 9.2 7.5e-140 466.4 9.2 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGD86979.1 - 1.5e-30 106.4 0.1 2.5e-30 105.7 0.1 1.4 1 0 0 1 1 1 1 ML-like domain DUF2371 PF10177.9 EGD86979.1 - 0.046 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) RseC_MucC PF04246.12 EGD86979.1 - 3.4 7.6 8.7 5.4 7.0 0.8 3.0 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC TFIIIC_sub6 PF10419.9 EGD86980.1 - 8.4e-27 92.9 0.0 1.3e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain SIT PF15330.6 EGD86980.1 - 0.18 12.3 0.1 1 9.8 0.0 2.1 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT MFS_1 PF07690.16 EGD86985.1 - 5.7e-28 97.9 30.6 1.8e-22 79.7 33.6 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGD86985.1 - 6.7e-07 28.1 2.7 6.7e-07 28.1 2.7 2.4 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGD86985.1 - 0.0036 16.2 5.2 0.0036 16.2 5.2 2.7 2 1 2 4 4 4 3 Sugar (and other) transporter PPR_2 PF13041.6 EGD86987.2 - 7.7e-12 45.2 0.1 0.056 13.6 0.0 6.1 5 3 1 6 6 6 3 PPR repeat family PPR PF01535.20 EGD86987.2 - 1.1e-05 25.3 8.0 0.61 10.5 0.0 6.8 7 0 0 7 7 7 2 PPR repeat TPR_14 PF13428.6 EGD86987.2 - 0.0084 16.9 0.0 22 6.2 0.0 5.1 7 0 0 7 7 7 1 Tetratricopeptide repeat DDT PF02791.17 EGD86987.2 - 0.034 14.5 0.7 0.48 10.8 0.1 2.8 2 0 0 2 2 2 0 DDT domain TPR_4 PF07721.14 EGD86987.2 - 0.15 12.7 0.0 91 4.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S18 PF01084.20 EGD86988.1 - 4e-16 59.0 0.2 7.6e-16 58.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Cro PF09048.10 EGD86988.1 - 0.013 15.6 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Cro WD40 PF00400.32 EGD86989.1 - 3.1e-36 122.8 27.2 5e-05 24.0 0.2 10.9 11 1 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD86989.1 - 1.1e-19 70.5 4.4 3.9e-05 23.8 0.0 6.3 4 2 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 EGD86989.1 - 0.001 18.9 0.0 0.029 14.3 0.0 2.6 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal Ge1_WD40 PF16529.5 EGD86989.1 - 0.0015 17.5 0.2 21 4.0 0.0 4.4 4 2 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGD86989.1 - 0.0023 17.8 1.2 23 5.1 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat IRF PF00605.17 EGD86989.1 - 0.21 11.9 1.5 15 5.9 0.2 2.5 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor Peptidase_M36 PF02128.15 EGD86992.2 - 4.4e-98 328.8 10.2 4.9e-95 318.8 10.2 2.0 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 EGD86992.2 - 0.0099 15.7 0.1 0.018 14.9 0.1 1.4 1 1 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M36 PF02128.15 EGD86993.1 - 1.3e-155 518.2 5.0 1.6e-155 517.8 5.0 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGD86993.1 - 9.1e-18 63.8 4.3 1.8e-17 62.9 4.3 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EGD86993.1 - 0.052 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain MFS_1 PF07690.16 EGD86995.2 - 1.1e-17 64.0 24.0 1.1e-17 64.0 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3328 PF11807.8 EGD86996.1 - 7.5e-24 84.7 0.0 1e-23 84.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ycf9 PF01737.17 EGD86996.1 - 0.048 13.5 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 YCF9 DUF4869 PF16163.5 EGD86997.1 - 0.14 11.8 0.3 0.18 11.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4869) CitT PF12431.8 EGD86997.1 - 1.3 9.5 3.6 32 5.0 0.3 2.6 2 0 0 2 2 2 0 Transcriptional regulator DUF3328 PF11807.8 EGD86998.2 - 1e-25 90.8 0.3 1.5e-25 90.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EGD86999.2 - 3.1e-27 95.8 1.1 4.2e-27 95.3 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Carb_anhydrase PF00194.21 EGD87001.2 - 1.7e-33 116.2 0.0 3.3e-33 115.3 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CA_like PF10563.9 EGD87001.2 - 0.048 13.6 0.1 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 Putative carbonic anhydrase Mitochondr_Som1 PF11093.8 EGD87002.1 - 0.073 13.1 0.1 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial export protein Som1 Alk_phosphatase PF00245.20 EGD87003.1 - 2.6e-106 356.1 0.1 3.1e-106 355.8 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EGD87003.1 - 1.1e-07 31.5 0.0 5e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily ALMT PF11744.8 EGD87004.2 - 0.074 11.9 0.0 0.074 11.9 0.0 1.9 2 1 1 3 3 3 0 Aluminium activated malate transporter YajC PF02699.15 EGD87004.2 - 0.086 12.7 0.2 0.26 11.2 0.2 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit KIP1 PF07765.12 EGD87004.2 - 1.5 9.0 3.3 4.9 7.3 0.2 2.6 2 1 1 3 3 3 0 KIP1-like protein SAGA-Tad1 PF12767.7 EGD87005.1 - 1.9e-54 184.9 0.0 2.5e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PRP1_N PF06424.12 EGD87006.1 - 1.2e-53 181.5 7.9 3e-53 180.2 7.9 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EGD87006.1 - 2.2e-28 96.5 26.2 0.0038 17.9 0.1 14.2 5 4 10 15 15 14 7 Tetratricopeptide repeat TPR_19 PF14559.6 EGD87006.1 - 9.2e-26 90.2 6.8 1.2e-06 29.0 0.1 9.7 6 3 2 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGD87006.1 - 1e-09 37.8 9.1 0.27 11.4 0.0 8.9 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGD87006.1 - 1.2e-08 34.5 3.0 0.093 13.0 0.0 7.9 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGD87006.1 - 2e-08 34.1 1.6 2.6 8.6 0.0 8.7 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGD87006.1 - 6.9e-07 29.8 13.3 0.22 12.2 0.0 7.6 7 1 1 8 8 8 1 Tetratricopeptide repeat NARP1 PF12569.8 EGD87006.1 - 7.1e-07 28.5 8.6 0.0099 14.8 0.0 5.5 4 1 2 6 6 6 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 EGD87006.1 - 9.1e-06 25.7 3.8 0.043 14.0 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGD87006.1 - 0.00016 21.2 1.3 33 4.3 0.0 6.6 7 1 1 8 8 8 0 TPR repeat TPR_1 PF00515.28 EGD87006.1 - 0.00025 20.7 1.6 0.88 9.5 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat ZNRF_3_ecto PF18212.1 EGD87006.1 - 0.013 15.5 0.2 37 4.4 0.0 4.7 6 0 0 6 6 6 0 ZNRF-3 Ectodomain TPR_12 PF13424.6 EGD87006.1 - 0.017 15.4 5.0 20 5.6 0.1 6.2 7 1 0 7 7 6 0 Tetratricopeptide repeat AdenylateSensor PF16579.5 EGD87006.1 - 0.062 13.8 0.7 11 6.4 0.0 3.7 3 1 1 4 4 4 0 Adenylate sensor of SNF1-like protein kinase DUF3808 PF10300.9 EGD87006.1 - 0.096 11.4 0.0 3.4 6.3 0.0 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF3808) TPR_7 PF13176.6 EGD87006.1 - 0.3 11.2 2.4 1.1e+02 3.2 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGD87006.1 - 0.44 10.2 21.4 1.1 8.9 0.1 4.8 3 1 1 5 5 5 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 EGD87006.1 - 4.5 8.1 12.5 42 5.1 0.0 6.9 9 0 0 9 9 6 0 Tetratricopeptide repeat RrnaAD PF00398.20 EGD87007.1 - 3.2e-64 216.6 0.0 4.5e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGD87007.1 - 1.8e-07 31.7 0.0 4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD87007.1 - 1.1e-05 26.0 0.0 3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGD87007.1 - 0.00011 22.1 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EGD87007.1 - 0.00025 20.4 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EGD87007.1 - 0.00091 19.9 0.0 0.0071 17.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD87007.1 - 0.001 18.9 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGD87007.1 - 0.0012 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 EGD87007.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.13 EGD87007.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EGD87007.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EGD87007.1 - 0.03 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 EGD87007.1 - 0.038 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EGD87007.1 - 0.044 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase DREV PF05219.12 EGD87007.1 - 0.052 12.6 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.17 EGD87007.1 - 0.055 13.1 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.7 EGD87007.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RabGAP-TBC PF00566.18 EGD87008.2 - 2.5e-46 158.0 0.0 1.1e-45 156.0 0.0 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 EGD87010.1 - 7.5e-33 112.2 0.3 2.7e-15 56.0 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGD87010.1 - 1.7e-10 40.9 0.3 0.00063 19.8 0.1 3.0 2 2 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 EGD87010.1 - 0.0029 17.6 0.1 2 8.5 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 EGD87010.1 - 0.011 15.7 0.1 5.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Phytochelatin PF05023.14 EGD87010.1 - 0.13 11.5 2.1 1.3 8.2 0.0 2.7 3 1 0 3 3 3 0 Phytochelatin synthase MCRS_N PF13325.6 EGD87010.1 - 0.65 10.0 2.7 1.3 8.9 2.7 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein LOH1CR12 PF10158.9 EGD87010.1 - 0.77 9.8 5.0 2.1 8.4 5.0 1.6 1 0 0 1 1 1 0 Tumour suppressor protein PHD PF00628.29 EGD87011.1 - 4.2e-08 33.0 8.2 4.2e-08 33.0 8.2 2.5 3 0 0 3 3 3 1 PHD-finger JmjC PF02373.22 EGD87011.1 - 6.7e-08 33.0 0.0 6.7e-08 33.0 0.0 2.7 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGD87011.1 - 6.7e-08 32.5 0.0 2e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Cupin-like domain JHD PF17811.1 EGD87011.1 - 1.2e-06 29.0 0.3 2.4e-06 28.0 0.3 1.4 1 0 0 1 1 1 1 Jumonji helical domain PHD_2 PF13831.6 EGD87011.1 - 4 7.1 9.7 3.2 7.4 7.5 2.1 2 0 0 2 2 2 0 PHD-finger COG4 PF08318.12 EGD87012.1 - 2.3e-123 411.5 0.0 3.1e-123 411.2 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein SIR2 PF02146.17 EGD87013.2 - 1.2e-56 191.5 0.0 1.7e-56 190.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EGD87013.2 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Hexokinase_2 PF03727.16 EGD87014.1 - 4.2e-81 271.9 0.0 5.8e-81 271.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGD87014.1 - 8.6e-73 244.5 0.0 1.1e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase PikAIV_N PF18605.1 EGD87015.2 - 0.042 13.4 5.8 1.2 8.8 0.7 3.1 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain STIMATE PF12400.8 EGD87016.1 - 8.7e-38 129.7 7.2 1.5e-37 128.9 7.2 1.4 1 0 0 1 1 1 1 STIMATE family Mucin PF01456.17 EGD87016.1 - 5.9 6.9 16.6 11 6.0 16.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RRM_1 PF00076.22 EGD87018.1 - 3.8e-19 68.3 0.3 5.6e-19 67.7 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGD87018.1 - 3.9e-06 26.5 0.0 4.2e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGD87018.1 - 0.0021 17.9 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Ammonium_transp PF00909.21 EGD87019.2 - 4.3e-114 381.3 28.3 5e-114 381.1 28.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family E1-E2_ATPase PF00122.20 EGD87020.1 - 3.2e-46 157.2 0.3 3.2e-46 157.2 0.3 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGD87020.1 - 2.9e-44 151.0 0.1 2.9e-44 151.0 0.1 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGD87020.1 - 5.9e-21 75.7 2.0 8.2e-20 72.0 2.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGD87020.1 - 7.5e-21 73.6 0.0 1.7e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGD87020.1 - 5.4e-12 45.6 0.0 1.2e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGD87020.1 - 1.9e-05 24.5 1.5 0.00038 20.3 0.9 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CARD_2 PF16739.5 EGD87020.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Caspase recruitment domain Rad21_Rec8_N PF04825.13 EGD87021.1 - 1.1e-37 128.5 0.0 2e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGD87021.1 - 3.3e-07 29.5 0.3 6.9e-07 28.5 0.3 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Zn_clus PF00172.18 EGD87025.1 - 0.0035 17.4 9.0 0.0035 17.4 9.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EGD87025.1 - 0.036 14.1 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold Flavokinase PF01687.17 EGD87027.1 - 4.4e-31 107.5 0.0 6.3e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase RSN1_7TM PF02714.15 EGD87028.2 - 1.3e-85 287.1 28.3 1.3e-85 287.1 28.3 1.9 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGD87028.2 - 6.5e-47 159.2 1.1 6.5e-47 159.2 1.1 3.9 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGD87028.2 - 9.2e-26 91.1 2.5 7.8e-14 52.3 0.9 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EGD87028.2 - 1.1e-13 51.2 1.6 1.5e-13 50.7 0.0 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF2149 PF09919.9 EGD87028.2 - 0.18 12.1 0.4 5 7.4 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2149) SnoaL_2 PF12680.7 EGD87029.2 - 4.6e-06 27.2 0.0 8.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EGD87029.2 - 0.00021 21.1 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.18 EGD87029.2 - 0.033 13.7 0.0 1.3 8.5 0.0 2.2 1 1 1 2 2 2 0 Dienelactone hydrolase family Indigoidine_A PF04227.12 EGD87030.1 - 1.2e-123 412.2 0.7 1.6e-123 411.7 0.7 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EGD87030.1 - 3.8e-13 49.4 0.0 3.1e-07 30.0 0.0 3.2 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.14 EGD87031.2 - 1.8e-126 422.9 0.1 2.1e-126 422.7 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I VTC PF09359.10 EGD87032.2 - 2.6e-100 335.3 0.3 4.2e-100 334.7 0.3 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 EGD87032.2 - 9.7e-13 48.8 7.4 7.6e-06 26.1 0.0 3.4 2 1 1 3 3 3 3 SPX domain DUF202 PF02656.15 EGD87032.2 - 2.5e-11 43.8 3.6 2.5e-11 43.8 3.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Ank_2 PF12796.7 EGD87034.1 - 0.0011 19.6 0.2 0.2 12.3 0.1 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGD87034.1 - 0.016 15.6 0.0 0.062 13.8 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 EGD87034.1 - 0.044 14.4 0.0 0.94 10.1 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Band_7 PF01145.25 EGD87035.1 - 1.7e-22 80.3 6.2 2.9e-22 79.5 6.2 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family CSTF2_hinge PF14327.6 EGD87036.1 - 2.4e-32 111.2 2.5 2.4e-32 111.2 2.5 2.2 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EGD87036.1 - 6.9e-20 70.6 0.0 1.2e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EGD87036.1 - 4.4e-18 64.6 8.8 2.2e-17 62.4 8.8 2.3 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 EGD87036.1 - 0.0096 16.0 0.1 1 9.5 0.0 2.5 1 1 1 2 2 2 1 RNA recognition motif Spo7_2_N PF15407.6 EGD87036.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_Rrp7 PF17799.1 EGD87036.1 - 0.021 14.6 0.0 2.2 8.1 0.0 2.3 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 EGD87036.1 - 0.06 13.2 0.0 0.2 11.5 0.0 1.8 1 1 0 1 1 1 0 Occluded RNA-recognition motif MCCD1 PF15707.5 EGD87036.1 - 0.54 10.7 4.1 0.55 10.7 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial coiled-coil domain protein 1 CCDC53 PF10152.9 EGD87036.1 - 2 8.8 4.9 0.76 10.2 1.9 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SNF2_N PF00176.23 EGD87037.2 - 4.5e-21 75.0 0.0 2.1e-12 46.4 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 EGD87037.2 - 7.7e-10 38.6 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase ResIII PF04851.15 EGD87037.2 - 0.04 13.9 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-piccolo PF05715.13 EGD87037.2 - 1.3 9.2 4.9 3.5 7.8 4.9 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger 2Fe-2S_thioredx PF01257.19 EGD87038.1 - 6.4e-59 198.0 0.0 8.2e-59 197.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF4139 PF13598.6 EGD87039.2 - 4.1e-30 105.1 0.9 5.6e-30 104.6 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4139) Nucleoporin_FG PF13634.6 EGD87039.2 - 0.17 12.8 6.3 0.38 11.6 6.3 1.5 1 0 0 1 1 1 0 Nucleoporin FG repeat region V_ATPase_I PF01496.19 EGD87039.2 - 0.76 7.6 5.2 1.1 7.1 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 EGD87039.2 - 1.9 8.3 8.3 3.6 7.3 8.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HAUS6_N PF14661.6 EGD87039.2 - 8.9 5.8 10.2 17 4.9 10.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Sua5_yciO_yrdC PF01300.18 EGD87040.1 - 6.5e-54 182.1 0.0 1e-53 181.5 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EGD87040.1 - 2.8e-31 108.9 0.0 4.8e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding NFACT-C PF11923.8 EGD87041.2 - 5.6e-37 125.9 0.1 5.6e-37 125.9 0.1 2.9 3 0 0 3 3 3 1 NFACT protein C-terminal domain Clat_adaptor_s PF01217.20 EGD87042.1 - 7.7e-14 51.8 0.0 1.7e-12 47.5 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain DUF2046 PF09755.9 EGD87043.1 - 0.033 13.4 0.6 0.056 12.7 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) D5_N PF08706.11 EGD87043.1 - 0.044 14.0 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 D5 N terminal like Tmemb_cc2 PF10267.9 EGD87043.1 - 0.17 11.0 1.1 0.27 10.3 1.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TLE_N PF03920.15 EGD87043.1 - 0.19 11.8 0.3 0.33 11.0 0.3 1.3 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DUF948 PF06103.11 EGD87044.1 - 0.053 13.8 0.7 0.11 12.8 0.7 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1515 PF07439.11 EGD87044.1 - 0.11 12.5 9.2 0.034 14.2 3.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF4407 PF14362.6 EGD87044.1 - 0.53 9.6 11.1 1.6 8.0 11.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TTKRSYEDQ PF10212.9 EGD87044.1 - 1.4 7.8 10.6 0.16 10.9 5.2 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Bacillus_HBL PF05791.11 EGD87044.1 - 1.4 8.7 7.6 0.7 9.7 3.8 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.11 EGD87044.1 - 1.7 9.1 10.7 12 6.4 0.3 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EGD87044.1 - 2 8.4 6.1 1.4 9.0 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EGD87044.1 - 3.2 7.8 10.4 10 6.1 10.4 1.9 1 0 0 1 1 1 0 Laminin Domain II MPS2 PF17060.5 EGD87044.1 - 6.5 5.9 11.6 12 5.1 11.6 1.5 1 0 0 1 1 1 0 Monopolar spindle protein 2 FAM76 PF16046.5 EGD87044.1 - 9 5.5 13.4 1.5 8.1 7.2 2.3 2 0 0 2 2 2 0 FAM76 protein DUF1265 PF06887.14 EGD87045.2 - 0.23 11.4 1.5 0.53 10.3 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) DUF3275 PF11679.8 EGD87045.2 - 1.1 9.2 3.1 0.76 9.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Ribosomal_L16 PF00252.18 EGD87046.1 - 4.4e-43 146.4 0.1 6.1e-43 146.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e APH PF01636.23 EGD87049.1 - 6.1e-08 32.9 0.1 6.8e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD87049.1 - 0.0051 16.4 0.0 0.0068 16.0 0.0 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EGD87049.1 - 0.26 10.1 0.0 0.36 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) AAA PF00004.29 EGD87052.1 - 2.4e-19 70.1 0.0 6.7e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGD87052.1 - 0.00014 22.3 0.4 0.0013 19.2 0.0 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGD87052.1 - 0.00053 20.0 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGD87052.1 - 0.004 16.9 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EGD87052.1 - 0.0054 17.0 1.0 0.048 13.9 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 EGD87052.1 - 0.0068 17.0 0.0 0.045 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGD87052.1 - 0.015 15.0 0.0 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Zot PF05707.12 EGD87052.1 - 0.019 14.6 0.1 0.14 11.8 0.0 2.1 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) Mg_chelatase PF01078.21 EGD87052.1 - 0.04 13.3 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EGD87052.1 - 0.066 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 EGD87052.1 - 0.081 13.2 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGD87052.1 - 0.086 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EGD87052.1 - 0.14 11.8 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGD87052.1 - 0.2 11.0 0.0 0.4 10.0 0.0 1.5 1 0 0 1 1 1 0 KaiC FA_hydroxylase PF04116.13 EGD87053.2 - 2.8e-21 76.2 12.1 2.8e-21 76.2 12.1 1.9 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily HA2 PF04408.23 EGD87054.2 - 4.8e-21 75.1 1.1 8.9e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGD87054.2 - 3.1e-12 46.8 0.0 7.8e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGD87054.2 - 0.00036 20.4 0.0 0.0012 18.7 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 EGD87054.2 - 0.0049 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGD87054.2 - 0.028 14.7 0.0 0.097 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EGD87054.2 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 EGD87054.2 - 0.12 12.9 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Trypsin_2 PF13365.6 EGD87058.1 - 2.4e-06 28.5 0.0 6e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_C3 PF00548.20 EGD87058.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) RTA1 PF04479.13 EGD87060.2 - 1.6e-39 135.7 2.5 1.9e-39 135.4 2.5 1.0 1 0 0 1 1 1 1 RTA1 like protein Fig1 PF12351.8 EGD87061.1 - 5e-07 29.8 2.3 6.9e-07 29.4 2.3 1.2 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF3533 PF12051.8 EGD87061.1 - 0.0042 16.1 1.0 0.0062 15.5 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) STE3 PF02076.15 EGD87061.1 - 0.15 11.3 8.8 0.048 12.9 0.8 2.2 1 1 1 2 2 2 0 Pheromone A receptor Fungal_lectin PF07938.12 EGD87062.1 - 2.1e-139 464.1 0.5 2.4e-139 463.9 0.5 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin TauD PF02668.16 EGD87063.1 - 8.4e-30 104.5 0.0 1.1e-29 104.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TSSC4 PF15264.6 EGD87063.1 - 0.081 13.2 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 Complex1_LYR_2 PF13233.6 EGD87066.1 - 5.5e-20 71.9 0.0 7e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGD87066.1 - 3.6e-09 36.6 0.0 6.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MTS PF05175.14 EGD87067.1 - 0.00029 20.5 0.0 0.6 9.6 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_12 PF08242.12 EGD87067.1 - 0.11 13.2 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.22 EGD87068.2 - 6.5e-17 61.0 0.0 8.7e-17 60.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGD87068.2 - 0.0088 16.2 0.0 0.019 15.1 0.0 1.5 2 0 0 2 2 2 1 Ataxin 2 SM domain F-box-like PF12937.7 EGD87069.1 - 1.3e-05 25.0 0.1 1.3e-05 25.0 0.1 2.7 3 1 1 4 4 4 1 F-box-like F-box PF00646.33 EGD87069.1 - 0.002 17.9 0.1 0.0083 16.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGD87069.1 - 0.033 14.1 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 F-box zf-C2H2 PF00096.26 EGD87071.1 - 4.9e-06 26.7 2.4 0.035 14.6 0.5 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD87071.1 - 0.037 14.9 9.4 0.47 11.4 0.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 EGD87071.1 - 0.044 14.3 0.4 0.087 13.4 0.4 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF2545 PF10810.8 EGD87073.1 - 0.019 15.1 0.3 0.025 14.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) DUF936 PF06075.12 EGD87074.1 - 0.0023 16.9 9.6 0.003 16.6 9.6 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) PBP_sp32 PF07222.12 EGD87074.1 - 0.012 15.1 9.3 0.015 14.7 9.3 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ribosomal_60s PF00428.19 EGD87074.1 - 0.045 14.3 20.9 0.068 13.8 3.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein THOC2_N PF16134.5 EGD87074.1 - 0.44 9.1 7.6 0.59 8.7 7.6 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Presenilin PF01080.17 EGD87074.1 - 2.1 7.1 8.7 2.6 6.7 8.7 1.1 1 0 0 1 1 1 0 Presenilin GTP_EFTU PF00009.27 EGD87075.1 - 9.2e-09 35.1 0.0 2.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGD87075.1 - 0.0016 18.4 0.4 0.4 10.6 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 EGD87075.1 - 0.0023 18.5 0.0 0.0073 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGD87075.1 - 0.011 16.3 0.0 0.028 15.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 EGD87075.1 - 0.021 14.2 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 EGD87075.1 - 0.027 14.9 0.2 0.095 13.1 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 EGD87075.1 - 0.042 14.0 0.6 0.076 13.1 0.6 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 EGD87075.1 - 0.058 13.1 0.4 0.15 11.8 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGD87075.1 - 0.11 12.5 0.1 0.59 10.2 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EGD87075.1 - 0.17 11.6 0.7 2.2 8.0 0.7 2.2 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Pkr1 PF08636.10 EGD87076.1 - 3.8e-30 103.9 5.0 5e-30 103.4 5.0 1.2 1 0 0 1 1 1 1 ER protein Pkr1 Phage_Gp23 PF10669.9 EGD87076.1 - 0.058 13.7 2.9 0.75 10.1 2.9 2.1 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) ANAPC2 PF08672.11 EGD87077.1 - 1.8e-22 79.6 0.3 5.6e-22 78.0 0.3 1.9 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 EGD87077.1 - 3.3e-22 78.9 0.1 6.4e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Cullin family DUF3235 PF11574.8 EGD87077.1 - 0.15 13.0 6.1 0.32 11.9 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Rhodanese PF00581.20 EGD87078.2 - 0.11 13.0 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Rhodanese-like domain DUF1633 PF07794.11 EGD87080.1 - 0.0028 15.9 1.5 0.0031 15.8 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1633) F-box-like PF12937.7 EGD87081.1 - 9.8e-09 35.0 1.0 6.4e-08 32.4 0.6 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGD87081.1 - 6.6e-07 29.0 0.5 1.8e-06 27.7 0.5 1.7 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.17 EGD87081.1 - 0.13 12.4 0.5 3.3 8.0 0.6 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.27 EGD87082.1 - 4.1e-58 193.3 6.9 3.8e-21 74.8 0.2 4.5 4 1 0 4 4 4 3 Mitochondrial carrier protein KAR9 PF08580.10 EGD87084.1 - 2.7e-242 806.2 0.9 2.7e-242 806.2 0.9 2.7 2 2 0 2 2 2 1 Yeast cortical protein KAR9 T3SS_ExsE PF18286.1 EGD87085.1 - 0.15 12.0 0.1 0.8 9.7 0.1 2.4 1 0 0 1 1 1 0 Type III secretion system ExsE CRAL_TRIO PF00650.20 EGD87086.1 - 6.8e-36 123.4 0.0 9.9e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGD87086.1 - 4.7e-07 29.9 0.2 1.6e-06 28.2 0.2 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGD87086.1 - 0.0036 17.4 0.0 0.0074 16.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 EGD87086.1 - 0.096 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Acylphosphatase PF00708.18 EGD87088.1 - 1.5e-24 86.2 0.1 1.7e-24 86.1 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase AOX PF01786.17 EGD87089.1 - 5.5e-100 333.4 0.0 6.6e-100 333.1 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase adh_short_C2 PF13561.6 EGD87090.1 - 4.9e-52 176.8 0.0 6.6e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD87090.1 - 8.9e-47 159.1 0.0 1.2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD87090.1 - 2.2e-07 31.0 0.0 3.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 KR domain PALP PF00291.25 EGD87090.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme THF_DHG_CYH_C PF02882.19 EGD87090.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EGD87090.1 - 0.022 14.2 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EGD87090.1 - 0.022 14.1 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MBOAT PF03062.19 EGD87092.1 - 3.6e-45 154.8 15.2 4e-34 118.5 7.5 2.3 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family FA_desaturase PF00487.24 EGD87093.1 - 4.4e-29 102.1 22.0 7e-29 101.4 22.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGD87093.1 - 2.6e-07 30.7 0.0 5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-HIT PF04438.16 EGD87097.1 - 1.1e-09 37.9 7.7 1.7e-09 37.4 7.7 1.3 1 0 0 1 1 1 1 HIT zinc finger Dopey_N PF04118.14 EGD87098.2 - 2e-39 135.5 0.0 2.2e-38 132.1 0.0 2.7 3 1 0 3 3 3 1 Dopey, N-terminal SARS_3b PF12383.8 EGD87098.2 - 0.0084 16.2 0.3 0.022 14.9 0.3 1.7 1 0 0 1 1 1 1 Severe acute respiratory syndrome coronavirus 3b protein DEAD PF00270.29 EGD87100.2 - 4.3e-22 78.7 0.0 9.9e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD87100.2 - 2.4e-21 76.1 0.4 2.6e-17 63.2 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RQC PF09382.10 EGD87100.2 - 4.1e-14 52.3 0.0 9.9e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 EGD87100.2 - 6.9e-14 52.3 8.9 6.9e-14 52.3 8.9 2.3 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 EGD87100.2 - 2.1e-06 27.9 0.0 5.3e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4110 PF13422.6 EGD87101.1 - 1.3e-32 111.7 0.2 1.3e-32 111.7 0.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 EGD87101.1 - 9.8e-27 92.7 10.3 4.4e-10 39.4 0.0 6.5 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EGD87101.1 - 1.3e-24 85.9 10.4 2.9e-09 37.0 0.1 6.4 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGD87101.1 - 1.3e-16 60.1 2.8 7.9e-06 25.7 0.0 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 EGD87101.1 - 9.2e-16 57.5 4.5 0.00025 21.2 0.1 5.3 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 EGD87101.1 - 4.2e-13 48.7 5.3 1.3e-05 24.7 0.0 4.3 3 1 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 EGD87101.1 - 3.4e-12 45.8 5.0 0.00092 19.1 0.0 6.0 6 1 0 6 6 6 3 Kelch motif Pyridoxal_deC PF00282.19 EGD87102.1 - 6.6e-25 87.6 0.0 3.9e-23 81.8 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EGD87102.1 - 0.08 12.2 0.0 0.13 11.5 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Glyco_hydro_61 PF03443.14 EGD87103.1 - 0.00059 19.8 0.0 0.0071 16.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 PepSY_TM PF03929.16 EGD87104.1 - 0.018 14.7 1.3 0.031 14.0 1.3 1.5 1 1 0 1 1 1 0 PepSY-associated TM region DUF4620 PF15399.6 EGD87104.1 - 0.4 11.1 6.0 0.95 9.8 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) Musclin PF11037.8 EGD87105.1 - 0.17 11.8 0.3 0.28 11.1 0.3 1.3 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Beta-lactamase PF00144.24 EGD87106.2 - 5.5e-53 180.3 0.0 7.5e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase AMP-binding PF00501.28 EGD87107.1 - 7e-149 496.0 0.0 4e-75 253.0 0.2 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EGD87107.1 - 1e-75 255.2 0.0 8.2e-41 140.1 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EGD87107.1 - 7e-22 77.6 0.1 6.5e-11 42.4 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGD87107.1 - 0.0031 18.4 0.0 0.74 10.8 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EGD87107.1 - 0.016 13.8 0.0 0.034 12.8 0.0 1.4 1 0 0 1 1 1 0 Transferase family SnoaL_2 PF12680.7 EGD87108.2 - 0.00039 21.0 0.0 0.0011 19.6 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like domain Methyltransf_25 PF13649.6 EGD87109.2 - 6.8e-10 39.5 0.0 1e-09 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD87109.2 - 5e-07 30.3 0.0 7.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD87109.2 - 4.6e-06 26.1 0.0 4.9e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGD87109.2 - 1.2e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD87109.2 - 0.00022 21.9 0.0 0.0003 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD87109.2 - 0.002 18.0 0.0 0.0023 17.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGD87109.2 - 0.0036 16.9 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DUF2139 PF09910.9 EGD87109.2 - 0.039 13.1 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) DUF501 PF04417.12 EGD87109.2 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF501) TehB PF03848.14 EGD87109.2 - 0.17 11.2 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Abhydrolase_1 PF00561.20 EGD87110.2 - 1.8e-14 54.0 0.0 2.9e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD87110.2 - 6.2e-08 32.2 0.0 1.5e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 EGD87110.2 - 0.0042 16.8 0.0 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Abhydrolase_6 PF12697.7 EGD87110.2 - 0.0043 17.7 0.0 0.0082 16.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGD87110.2 - 0.065 12.7 0.0 0.18 11.3 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family CENP-K PF11802.8 EGD87111.1 - 7e-05 22.5 4.5 0.2 11.2 1.9 2.7 2 1 0 2 2 2 2 Centromere-associated protein K Fib_alpha PF08702.10 EGD87111.1 - 0.29 11.3 6.2 0.42 10.8 0.4 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EGD87111.1 - 0.52 9.1 12.8 0.29 10.0 4.7 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein KH_1 PF00013.29 EGD87112.2 - 1.9e-43 146.1 4.0 1e-17 63.7 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGD87112.2 - 1.9e-11 43.6 2.0 0.011 15.5 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGD87112.2 - 1.3e-05 25.0 0.3 0.79 9.6 0.1 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 EGD87112.2 - 8.7e-05 22.5 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 KH-like RNA-binding domain KH_5 PF13184.6 EGD87112.2 - 0.0004 20.4 7.9 0.21 11.7 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain Pol_alpha_B_N PF08418.10 EGD87112.2 - 0.015 15.2 0.4 0.026 14.5 0.4 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PrgI PF12666.7 EGD87114.2 - 0.28 11.9 4.1 5.7 7.7 0.3 2.5 2 0 0 2 2 2 0 PrgI family protein TED_complement PF07678.14 EGD87118.2 - 0.061 12.3 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 A-macroglobulin TED domain Fungal_trans PF04082.18 EGD87119.2 - 3.5e-05 23.0 0.1 3.5e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain NUP214 PF16755.5 EGD87120.2 - 3.2e-12 46.4 0.0 4.9e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Syntaxin-6_N PF09177.11 EGD87120.2 - 0.021 15.4 0.0 0.064 13.8 0.0 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Proteasome PF00227.26 EGD87121.1 - 7.8e-48 162.5 0.1 9.5e-48 162.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EGD87121.1 - 7.4e-15 54.1 0.1 7.4e-15 54.1 0.1 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Methyltransf_23 PF13489.6 EGD87123.1 - 5.4e-27 94.6 0.0 7.6e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD87123.1 - 3.4e-10 40.5 0.0 7.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD87123.1 - 9.8e-10 38.4 0.0 1.2e-08 34.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD87123.1 - 5.8e-07 30.2 0.0 1.7e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD87123.1 - 8.4e-07 29.6 0.0 1.5e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGD87123.1 - 0.00064 19.2 0.8 0.002 17.6 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 EGD87123.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGD87123.1 - 0.027 13.8 0.0 0.22 10.8 0.0 2.3 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EGD87123.1 - 0.034 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGD87123.1 - 0.046 13.3 0.0 0.72 9.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 EGD87123.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Peptidase_M3 PF01432.20 EGD87124.1 - 2.9e-118 396.0 0.0 4.2e-118 395.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 EGD87124.1 - 0.17 12.2 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Effector protein ApoO PF09769.9 EGD87125.1 - 1.9e-41 141.1 1.1 2.4e-41 140.7 0.0 1.7 3 0 0 3 3 3 1 Apolipoprotein O GRASP55_65 PF04495.14 EGD87126.1 - 5.8e-42 143.3 0.0 6e-40 136.8 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EGD87126.1 - 0.11 12.4 0.0 22 5.0 0.0 2.4 2 0 0 2 2 2 0 PDZ domain Methyltransf_15 PF09445.10 EGD87127.1 - 1e-50 171.6 0.0 1.3e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EGD87127.1 - 1.1e-08 35.1 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EGD87127.1 - 2.2e-08 33.9 0.0 3.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 EGD87127.1 - 4.1e-07 29.9 0.0 5.7e-07 29.4 0.0 1.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 EGD87127.1 - 0.00044 20.2 0.0 0.00063 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 EGD87127.1 - 0.00055 19.5 0.0 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 EGD87127.1 - 0.0017 19.0 0.0 0.0035 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EGD87127.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.14 EGD87127.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EGD87127.1 - 0.046 13.1 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGD87127.1 - 0.047 14.3 0.0 0.086 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DNA_methylase PF00145.17 EGD87127.1 - 0.071 12.4 0.0 0.09 12.1 0.0 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DUF3591 PF12157.8 EGD87128.1 - 2.6e-186 619.6 0.5 3.7e-186 619.1 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 EGD87128.1 - 0.0051 16.8 0.7 0.0089 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGD87128.1 - 0.0067 16.3 1.2 0.016 15.0 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Pkinase PF00069.25 EGD87129.1 - 5.1e-48 163.7 0.9 1.7e-25 89.9 0.1 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87129.1 - 5.3e-20 71.8 0.0 1e-12 47.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGD87129.1 - 0.023 14.6 0.1 0.061 13.2 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGD87129.1 - 0.028 13.4 0.4 0.051 12.5 0.4 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FKBP_C PF00254.28 EGD87130.2 - 6.8e-31 106.4 0.1 2.9e-30 104.4 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EGD87130.2 - 2e-29 102.2 3.9 2e-29 102.2 3.9 2.8 2 2 0 2 2 2 1 Nucleoplasmin-like domain Utp14 PF04615.13 EGD87130.2 - 0.0075 14.9 32.6 0.01 14.5 32.6 1.2 1 0 0 1 1 1 1 Utp14 protein SurA_N PF09312.11 EGD87130.2 - 0.11 12.5 1.0 0.28 11.3 1.0 1.6 1 0 0 1 1 1 0 SurA N-terminal domain PRCC PF10253.9 EGD87130.2 - 0.21 12.3 17.3 0.049 14.4 9.0 2.4 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting IMS PF00817.20 EGD87131.1 - 1.5e-40 138.7 0.0 3.7e-40 137.4 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EGD87131.1 - 7.4e-25 87.2 0.0 1.7e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 EGD87131.1 - 3.6e-14 53.5 0.0 8.1e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 EGD87131.1 - 4.8e-14 51.2 8.1 1.4e-09 37.1 2.9 3.1 2 0 0 2 2 2 2 Ubiquitin binding region BRCT_2 PF16589.5 EGD87131.1 - 4.8e-10 39.7 0.0 2e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGD87131.1 - 1.6e-06 28.4 0.0 1.4e-05 25.4 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGD87131.1 - 3.9e-06 27.1 0.0 8.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain mCpol PF18182.1 EGD87131.1 - 0.00034 20.9 0.0 0.0012 19.2 0.0 1.9 1 0 0 1 1 1 1 minimal CRISPR polymerase domain PTCB-BRCT PF12738.7 EGD87131.1 - 0.023 14.7 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain DUF1805 PF08827.11 EGD87131.1 - 0.081 13.3 0.0 0.29 11.5 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) DJ-1_PfpI PF01965.24 EGD87132.1 - 4.7e-21 75.3 0.0 5.9e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EGD87132.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DUF4246 PF14033.6 EGD87133.1 - 1.2e-126 423.5 0.2 1.5e-126 423.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EGD87133.1 - 0.0005 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 EGD87133.1 - 0.069 14.0 0.0 0.19 12.6 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aminotran_1_2 PF00155.21 EGD87134.1 - 9.6e-74 248.7 0.0 1.1e-73 248.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1539 PF07560.11 EGD87137.1 - 0.027 14.6 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Con-6 PF10346.9 EGD87138.2 - 0.17 11.9 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Conidiation protein 6 OMPdecase PF00215.24 EGD87139.1 - 3e-75 252.7 0.0 3.4e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.18 EGD87140.1 - 6.6e-24 84.3 3.9 8.1e-24 84.0 3.9 1.1 1 0 0 1 1 1 1 MAPEG family MBOAT PF03062.19 EGD87141.1 - 6.8e-25 88.1 16.0 1.5e-24 87.0 16.1 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EGD87141.1 - 0.0071 16.6 2.6 0.02 15.2 2.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF2530 PF10745.9 EGD87141.1 - 1.4 9.2 8.6 2.1 8.6 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) WD40 PF00400.32 EGD87144.1 - 3.9e-33 113.0 31.5 3.7e-07 30.7 1.9 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD87144.1 - 6.7e-19 68.0 0.1 0.00014 22.1 0.0 5.2 3 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EGD87144.1 - 0.047 12.0 0.0 0.19 10.0 0.0 1.8 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz RNase_PH_C PF03725.15 EGD87145.2 - 2.8e-09 36.9 0.2 1.8e-08 34.3 0.1 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Pga1 PF10333.9 EGD87145.2 - 0.17 11.8 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator PhoLip_ATPase_C PF16212.5 EGD87146.1 - 8.4e-83 277.9 18.4 8.4e-83 277.9 18.4 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGD87146.1 - 1.1e-26 92.3 8.1 4.2e-26 90.4 8.1 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGD87146.1 - 1.4e-12 47.5 0.0 1.8e-11 44.0 0.0 2.6 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGD87146.1 - 6.6e-12 46.2 1.0 1.5e-07 31.9 0.1 3.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGD87146.1 - 2.9e-07 30.2 0.0 8.3e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGD87146.1 - 0.0021 17.8 0.2 0.0091 15.8 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase F-box_4 PF15966.5 EGD87147.2 - 0.055 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 F-box F-box PF00646.33 EGD87147.2 - 0.098 12.6 1.9 0.21 11.5 1.9 1.6 1 0 0 1 1 1 0 F-box domain NAD1 PF18778.1 EGD87147.2 - 0.12 12.4 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Glyco_hydro_18 PF00704.28 EGD87148.1 - 2.1e-11 44.1 1.6 6.2e-07 29.4 0.2 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 DNA_pol_B_thumb PF14791.6 EGD87149.1 - 2.5e-22 78.8 0.5 1.6e-21 76.2 0.3 2.5 3 0 0 3 3 3 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EGD87149.1 - 1.4e-17 63.2 0.9 2.9e-17 62.2 0.9 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 EGD87149.1 - 7.3e-17 61.6 0.0 4e-15 56.0 0.0 2.6 3 0 0 3 3 3 1 DNA polymerase beta palm HHH_8 PF14716.6 EGD87149.1 - 1.4e-10 41.4 0.0 4.6e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 EGD87149.1 - 0.026 14.9 0.0 0.081 13.4 0.0 1.8 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 EGD87149.1 - 0.053 14.1 0.0 0.2 12.3 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain Peptidase_S8 PF00082.22 EGD87150.1 - 2.1e-34 119.2 15.9 3.8e-34 118.3 15.9 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGD87150.1 - 1.8e-18 66.9 0.2 3.3e-18 66.1 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 NicO PF03824.16 EGD87151.1 - 2.2e-54 184.7 16.6 5.2e-53 180.2 7.0 2.5 3 0 0 3 3 3 2 High-affinity nickel-transport protein Peptidase_M14 PF00246.24 EGD87152.1 - 2.3e-73 247.6 0.0 3e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase SET PF00856.28 EGD87153.1 - 7.3e-14 52.5 0.2 1.5e-12 48.3 0.2 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.12 EGD87153.1 - 0.046 14.4 0.0 2.5 8.8 0.0 2.3 2 0 0 2 2 2 0 SAF domain zf-RING_UBOX PF13445.6 EGD87154.1 - 1.1e-05 25.4 8.5 2.8e-05 24.1 1.4 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGD87154.1 - 3e-05 23.8 8.5 0.00012 21.8 1.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGD87154.1 - 9.1e-05 22.7 10.6 0.0052 17.1 4.6 3.1 2 1 1 3 3 3 2 Ring finger domain zf-NOSIP PF15906.5 EGD87154.1 - 9.1e-05 22.5 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 EGD87154.1 - 9.1e-05 22.3 3.7 9.1e-05 22.3 3.7 2.8 2 1 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.12 EGD87154.1 - 0.00014 21.3 1.9 0.00014 21.3 1.9 3.3 2 1 1 3 3 2 2 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 EGD87154.1 - 0.00058 19.7 12.3 0.0014 18.5 1.9 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGD87154.1 - 0.0019 18.0 7.8 0.0035 17.2 1.0 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 EGD87154.1 - 0.0029 17.4 0.6 0.0088 15.9 0.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Atg14 PF10186.9 EGD87154.1 - 0.003 16.7 9.7 0.003 16.7 9.7 1.6 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 FYVE PF01363.21 EGD87154.1 - 0.0083 16.2 13.5 0.035 14.2 5.7 3.7 2 2 1 3 3 3 1 FYVE zinc finger DUF1195 PF06708.11 EGD87154.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Prok-RING_4 PF14447.6 EGD87154.1 - 0.018 14.9 5.2 0.018 14.9 5.2 3.5 3 1 1 4 4 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGD87154.1 - 0.45 10.7 12.6 0.4 10.9 5.5 3.5 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-FLZ PF04570.14 EGD87154.1 - 0.53 9.8 3.6 3.6 7.1 0.0 3.3 3 0 0 3 3 3 0 zinc-finger of the FCS-type, C2-C2 IBR PF01485.21 EGD87154.1 - 1.7 8.9 12.1 31 4.9 6.0 3.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain CDC45 PF02724.14 EGD87154.1 - 3.1 6.0 12.9 4.3 5.5 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Zn_ribbon_17 PF17120.5 EGD87154.1 - 8.1 6.1 10.1 4.5 7.0 0.6 2.7 3 0 0 3 3 2 0 Zinc-ribbon, C4HC2 type Sec7 PF01369.20 EGD87155.1 - 7.1e-31 107.3 0.2 1.1e-30 106.6 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EGD87155.1 - 5.4e-06 26.8 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGD87155.1 - 2.9e-05 24.5 0.1 9.9e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 PH domain BTB PF00651.31 EGD87156.1 - 0.049 13.9 0.0 0.8 10.0 0.0 2.6 3 0 0 3 3 3 0 BTB/POZ domain Endonuclease_NS PF01223.23 EGD87157.1 - 1e-64 218.5 0.0 1.3e-64 218.2 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Zip PF02535.22 EGD87158.2 - 1.4e-15 57.3 8.4 6.7e-15 55.1 8.2 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2040 PF09745.9 EGD87159.1 - 1.6e-38 131.5 15.9 1.6e-38 131.5 15.9 3.8 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) TPR_10 PF13374.6 EGD87159.1 - 0.048 13.5 0.2 19 5.3 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Big_3 PF07523.12 EGD87159.1 - 0.072 13.4 0.4 18 5.7 0.1 2.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Sedlin_N PF04628.13 EGD87160.1 - 6.1e-41 139.6 0.0 7.8e-41 139.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Herpes_capsid PF06112.11 EGD87160.1 - 0.0026 17.9 1.7 0.0033 17.5 1.7 1.3 1 0 0 1 1 1 1 Gammaherpesvirus capsid protein Sybindin PF04099.12 EGD87160.1 - 0.0029 17.5 0.0 0.06 13.3 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family NLBH PF05211.12 EGD87160.1 - 0.026 14.1 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) Isochorismatase PF00857.20 EGD87161.2 - 7.8e-38 130.4 0.0 4.3e-37 128.0 0.0 1.9 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.15 EGD87161.2 - 6.5e-06 26.8 0.1 1.6e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.11 EGD87161.2 - 0.058 13.8 0.0 0.094 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT Hexokinase_2 PF03727.16 EGD87162.2 - 5.9e-41 140.5 0.0 7.4e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGD87162.2 - 3.6e-08 33.5 0.0 6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Hexokinase NUDE_C PF04880.13 EGD87163.1 - 1.7e-57 194.8 11.8 1.7e-57 194.8 11.8 4.7 3 1 2 5 5 5 1 NUDE protein, C-terminal conserved region DUF16 PF01519.16 EGD87163.1 - 0.012 16.1 5.2 0.012 16.1 5.2 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 CLZ PF16526.5 EGD87163.1 - 0.015 15.6 3.4 0.015 15.6 3.4 3.5 4 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1729 PF08354.10 EGD87163.1 - 0.041 12.8 0.5 0.062 12.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) PSII_Pbs27 PF13326.6 EGD87163.1 - 0.12 12.7 3.0 0.29 11.5 3.0 1.6 1 0 0 1 1 1 0 Photosystem II Pbs27 ZapB PF06005.12 EGD87163.1 - 0.37 11.3 33.4 0.24 11.8 8.0 4.9 2 1 2 4 4 4 0 Cell division protein ZapB ADIP PF11559.8 EGD87163.1 - 2.2 8.3 26.0 5.5 7.1 4.8 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 EGD87163.1 - 8.2 5.7 27.7 3.9 6.8 13.9 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 EGD87163.1 - 9.5 6.3 33.9 0.68 10.0 8.2 4.0 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Chibby PF14645.6 EGD87163.1 - 9.9 6.6 12.9 6.8 7.1 4.1 3.0 1 1 0 2 2 2 0 Chibby family ACC_central PF08326.12 EGD87164.1 - 1.9e-283 942.2 0.0 2.3e-283 941.9 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EGD87164.1 - 1.7e-189 630.6 0.0 3.2e-189 629.7 0.0 1.4 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EGD87164.1 - 7.2e-54 182.5 0.0 1.4e-53 181.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGD87164.1 - 1.4e-28 99.6 0.1 2.9e-28 98.6 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGD87164.1 - 8.6e-23 80.5 0.0 9.8e-20 70.7 0.0 2.9 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGD87164.1 - 2.4e-15 56.1 0.2 6.8e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGD87164.1 - 8e-05 22.3 0.0 0.00026 20.6 0.0 1.9 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EGD87164.1 - 0.00017 21.7 0.0 0.00044 20.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Antiterm PF03589.13 EGD87164.1 - 0.059 13.7 0.0 0.82 10.0 0.0 2.7 2 0 0 2 2 2 0 Antitermination protein ATPgrasp_Ter PF15632.6 EGD87164.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon HeLo PF14479.6 EGD87165.1 - 0.00015 21.7 0.2 0.0038 17.1 0.2 2.3 1 1 0 1 1 1 1 Prion-inhibition and propagation Trypsin_2 PF13365.6 EGD87165.1 - 0.073 14.0 0.1 0.16 12.9 0.1 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain Pkinase_Tyr PF07714.17 EGD87165.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase RINGv PF12906.7 EGD87166.1 - 5.3e-16 58.5 10.1 9.4e-16 57.7 10.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EGD87166.1 - 0.0037 17.6 8.8 0.0067 16.7 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain BSP_II PF05432.11 EGD87166.1 - 0.032 13.9 13.2 0.085 12.5 13.2 1.6 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Use1 PF09753.9 EGD87166.1 - 0.042 13.6 0.4 6.5 6.4 0.2 2.2 2 0 0 2 2 2 0 Membrane fusion protein Use1 TRAP_alpha PF03896.16 EGD87166.1 - 0.25 10.5 3.2 0.45 9.7 3.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf-ANAPC11 PF12861.7 EGD87166.1 - 0.41 10.7 3.6 0.92 9.6 3.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RXT2_N PF08595.11 EGD87166.1 - 0.5 10.4 6.4 1.4 9.0 6.4 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Zf_RING PF16744.5 EGD87166.1 - 0.93 9.6 3.7 2 8.6 3.7 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_4 PF14570.6 EGD87166.1 - 1.4 8.8 6.6 2.3 8.1 6.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Merozoite_SPAM PF07133.11 EGD87166.1 - 1.4 8.9 23.1 2.8 7.9 23.1 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) zf-C3HC4_3 PF13920.6 EGD87166.1 - 3.4 7.6 5.6 6.7 6.7 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGD87166.1 - 4.2 7.6 6.7 9.2 6.5 6.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain RR_TM4-6 PF06459.12 EGD87166.1 - 4.5 7.0 7.8 9.4 6.0 7.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4843 PF16132.5 EGD87167.1 - 0.0053 16.3 0.1 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4843) Radical_SAM PF04055.21 EGD87167.1 - 0.19 12.1 0.4 4.4 7.6 0.0 2.9 3 0 0 3 3 3 0 Radical SAM superfamily PEP-utilisers_N PF05524.13 EGD87167.1 - 0.29 11.3 1.9 0.9 9.7 0.2 2.7 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Prominin PF05478.11 EGD87167.1 - 0.66 7.8 2.6 0.74 7.7 1.1 1.7 2 0 0 2 2 2 0 Prominin Med30 PF11315.8 EGD87167.1 - 0.77 10.0 3.7 1.2 9.4 0.2 2.9 4 0 0 4 4 4 0 Mediator complex subunit 30 PET10 PF17316.2 EGD87167.1 - 0.97 8.9 6.1 8.2 5.9 0.3 2.6 1 1 1 2 2 2 0 Petite colonies protein 10 Uso1_p115_C PF04871.13 EGD87167.1 - 6.6 7.1 10.5 0.28 11.6 1.4 2.8 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMEM208_SND2 PF05620.11 EGD87168.1 - 3.4e-54 183.1 0.0 3.8e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 TPR_1 PF00515.28 EGD87169.1 - 5.3e-41 136.8 7.3 1.1e-06 28.1 0.0 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGD87169.1 - 1.1e-35 118.9 13.0 0.00056 19.8 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EGD87169.1 - 4.7e-32 110.1 16.4 2.2e-24 85.5 0.4 4.6 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EGD87169.1 - 4.5e-27 91.9 8.9 0.00095 19.2 0.5 9.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGD87169.1 - 2.2e-26 91.2 6.4 1.2e-07 31.3 1.0 8.6 7 1 2 9 9 9 7 TPR repeat TPR_19 PF14559.6 EGD87169.1 - 4.7e-24 84.7 14.8 4.4e-08 33.5 0.4 7.3 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGD87169.1 - 6.1e-23 79.6 3.9 0.0021 18.7 0.1 9.6 7 2 3 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGD87169.1 - 3.4e-20 72.4 10.2 2e-09 37.9 0.2 8.2 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGD87169.1 - 3.2e-16 59.4 16.3 0.0039 17.4 0.1 8.2 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGD87169.1 - 3.9e-13 48.8 11.0 0.0077 16.5 0.1 9.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGD87169.1 - 1.8e-09 37.0 5.0 0.045 13.8 0.0 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGD87169.1 - 1.1e-06 28.9 10.8 2.2 9.1 0.1 7.8 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGD87169.1 - 2.1e-06 27.7 0.3 0.05 13.8 0.0 4.5 2 1 3 5 5 5 2 Tetratricopeptide repeat ChAPs PF09295.10 EGD87169.1 - 0.0035 16.4 0.0 0.28 10.1 0.0 2.5 1 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) PPTA PF01239.22 EGD87169.1 - 0.047 13.4 0.2 0.14 11.9 0.2 1.9 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat TPR_MalT PF17874.1 EGD87169.1 - 0.05 13.0 2.4 2.2 7.6 0.0 3.7 3 2 1 4 4 4 0 MalT-like TPR region TPR_10 PF13374.6 EGD87169.1 - 0.21 11.5 5.0 16 5.6 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGD87169.1 - 0.36 10.5 6.3 0.94 9.1 0.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain NARP1 PF12569.8 EGD87169.1 - 0.4 9.5 3.3 1.1 8.0 0.1 3.0 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 Acyltransferase PF01553.21 EGD87170.1 - 2.4e-30 104.9 0.0 4.5e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase ACPS PF01648.20 EGD87171.1 - 3.1e-14 53.1 0.0 1.2e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.19 EGD87173.1 - 2.1e-53 181.0 0.0 8e-43 146.5 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGD87173.1 - 1.5e-08 34.5 0.0 3.1e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EGD87173.1 - 0.0022 17.8 0.0 0.022 14.5 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 EGD87173.1 - 0.0046 16.6 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 EGD87173.1 - 0.0087 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family RRM_1 PF00076.22 EGD87174.1 - 1.6e-15 56.6 0.0 2.3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup54 PF13874.6 EGD87175.2 - 0.003 17.7 0.5 0.003 17.7 0.5 3.0 2 1 1 3 3 3 1 Nucleoporin complex subunit 54 NPV_P10 PF05531.12 EGD87175.2 - 0.15 12.5 1.9 1.5 9.3 0.1 3.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Rotamase PF00639.21 EGD87177.2 - 4.3e-24 85.3 0.1 5.2e-24 85.0 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EGD87177.2 - 2.8e-16 60.1 0.0 3.6e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EGD87177.2 - 2.8e-05 24.9 0.0 3.2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 EGD87177.2 - 0.19 12.5 0.0 0.27 11.9 0.0 1.2 1 0 0 1 1 1 0 X8 domain Pro_3_hydrox_C PF05373.11 EGD87178.2 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal RNA_POL_M_15KD PF02150.16 EGD87179.2 - 3.3e-12 46.0 1.0 3.3e-12 46.0 1.0 1.8 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit GFA PF04828.14 EGD87179.2 - 0.0046 17.3 2.0 0.29 11.5 0.1 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L14 PF00238.19 EGD87180.1 - 1.1e-47 161.1 1.5 1.2e-47 160.9 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Dak1_2 PF13684.6 EGD87180.1 - 0.097 11.7 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family SET PF00856.28 EGD87181.1 - 1.8e-08 35.0 0.0 4.9e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 SET domain HypA PF01155.19 EGD87181.1 - 0.083 12.9 0.3 0.083 12.9 0.3 2.4 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4519 PF15012.6 EGD87181.1 - 0.14 12.3 3.1 2.7 8.2 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DEAD PF00270.29 EGD87183.2 - 2.2e-31 109.0 0.0 4.1e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD87183.2 - 7.4e-20 71.3 0.0 3.7e-17 62.7 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGD87183.2 - 0.00012 22.2 0.5 0.0021 18.1 0.1 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGD87183.2 - 0.042 12.6 0.0 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Anillin PF08174.11 EGD87184.1 - 5.3e-09 36.6 0.9 1.4e-08 35.3 0.0 2.3 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.29 EGD87184.1 - 1.7e-07 31.7 0.0 5.6e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 PH domain PseudoU_synth_1 PF01416.20 EGD87185.2 - 1.7e-10 41.3 0.0 2.7e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase ATP_bind_2 PF03668.15 EGD87185.2 - 0.029 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family TFIIE_alpha PF02002.17 EGD87186.1 - 9.7e-19 67.2 0.0 2.1e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_Crp_2 PF13545.6 EGD87186.1 - 0.015 15.2 0.6 0.028 14.4 0.6 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TEX19 PF15553.6 EGD87186.1 - 7.9 6.4 6.9 1.2 9.1 1.4 2.2 2 0 0 2 2 2 0 Testis-expressed protein 19 MFS_1 PF07690.16 EGD87188.1 - 4e-16 58.9 55.0 4e-16 58.9 55.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1179 PF06678.11 EGD87188.1 - 7.3 6.6 5.3 0.78 9.8 0.3 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1179) PALP PF00291.25 EGD87189.2 - 1.3e-41 142.9 0.2 2.8e-41 141.9 0.2 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RNase_P_pop3 PF08228.11 EGD87191.2 - 7.1e-05 22.9 0.0 0.00013 22.1 0.0 1.4 1 1 0 1 1 1 1 RNase P subunit Pop3 DUF4712 PF15830.5 EGD87191.2 - 0.047 13.4 0.3 0.074 12.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) Hexapep PF00132.24 EGD87192.1 - 4.2e-12 45.3 10.9 3.9e-11 42.2 3.9 3.1 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGD87192.1 - 6.7e-12 44.9 9.7 2.9e-11 42.9 3.1 2.7 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EGD87192.1 - 8.6e-11 41.9 0.1 1.4e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Ank_2 PF12796.7 EGD87193.1 - 3.5e-38 130.1 18.6 9.9e-12 45.3 0.4 5.6 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGD87193.1 - 1.4e-34 117.7 13.8 8.1e-10 38.8 0.1 6.4 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGD87193.1 - 2.4e-34 117.2 11.0 3.1e-07 30.8 0.0 7.1 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD87193.1 - 5.7e-26 87.7 13.8 1.1e-05 25.4 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 EGD87193.1 - 9.7e-24 82.7 17.8 2.1e-06 27.9 0.1 8.3 9 0 0 9 9 9 4 Ankyrin repeat AIRC PF00731.20 EGD87194.1 - 9.3e-59 197.3 1.8 1.7e-58 196.4 1.8 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EGD87194.1 - 3.9e-52 176.3 0.0 7.6e-52 175.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EGD87194.1 - 1.4e-18 66.3 0.1 3.3e-18 65.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 EGD87194.1 - 1.7e-05 24.5 0.2 5.6e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AlaDh_PNT_C PF01262.21 EGD87194.1 - 0.00043 19.6 0.3 0.0009 18.6 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PrpR_N PF06506.11 EGD87194.1 - 0.0017 17.9 0.6 0.0055 16.3 0.1 2.1 2 0 0 2 2 2 1 Propionate catabolism activator Dala_Dala_lig_C PF07478.13 EGD87194.1 - 0.0075 15.8 0.0 0.09 12.3 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CoA_binding_2 PF13380.6 EGD87194.1 - 0.11 13.0 1.0 29 5.2 0.0 3.4 2 1 1 3 3 3 0 CoA binding domain SCA7 PF08313.12 EGD87195.2 - 2.9e-31 107.2 0.3 2.9e-31 107.2 0.3 2.3 2 1 0 2 2 2 1 SCA7, zinc-binding domain DUF2151 PF10221.9 EGD87195.2 - 0.066 11.8 7.5 0.09 11.4 7.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.14 EGD87195.2 - 0.56 8.4 7.0 0.78 8.0 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 EGD87195.2 - 1 8.3 6.4 2 7.3 6.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ATP-synt_Eps PF04627.13 EGD87195.2 - 1.2 9.2 6.7 3.3 7.8 6.7 1.8 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain mRNA_cap_enzyme PF01331.19 EGD87196.1 - 6e-52 176.3 0.4 8.5e-52 175.8 0.4 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EGD87196.1 - 5.2e-36 123.6 0.0 1e-35 122.6 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EGD87196.1 - 1.1e-08 35.0 0.6 7.9e-07 28.9 0.2 2.5 1 1 1 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_M PF01068.21 EGD87197.2 - 9.9e-60 201.7 0.5 1.6e-57 194.5 0.5 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGD87197.2 - 2.8e-38 132.0 0.4 5.5e-38 131.0 0.4 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGD87197.2 - 7.5e-28 97.0 0.0 3e-27 95.1 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EGD87197.2 - 2.4e-05 24.7 0.1 3.6e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 RNA ligase Synaptonemal_3 PF15191.6 EGD87197.2 - 0.07 12.9 0.0 1.1 9.1 0.0 2.6 2 1 0 2 2 2 0 Synaptonemal complex central element protein 3 CFEM PF05730.11 EGD87198.1 - 4.4e-10 39.5 4.7 6.4e-10 39.0 4.7 1.2 1 0 0 1 1 1 1 CFEM domain GMC_oxred_N PF00732.19 EGD87200.2 - 2.2e-47 161.9 0.0 2.7e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGD87200.2 - 1.9e-32 112.7 0.0 3.1e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EGD87200.2 - 0.0023 17.0 0.2 0.0044 16.1 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EGD87200.2 - 0.0031 17.7 0.0 0.0085 16.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGD87200.2 - 0.024 13.7 1.0 0.045 12.8 1.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EGD87200.2 - 0.03 13.6 0.4 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGD87200.2 - 0.05 13.2 0.1 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGD87200.2 - 0.053 12.7 0.1 0.091 12.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGD87200.2 - 0.074 12.3 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 EGD87200.2 - 0.086 11.7 0.6 0.13 11.1 0.6 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 EGD87200.2 - 0.11 11.2 0.4 0.15 10.7 0.4 1.1 1 0 0 1 1 1 0 HI0933-like protein FPN1 PF06963.12 EGD87201.1 - 3.1e-118 395.1 16.2 3.6e-118 394.9 16.2 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Transgly_assoc PF04226.13 EGD87201.1 - 1.6 9.1 6.7 22 5.4 0.9 3.9 3 0 0 3 3 3 0 Transglycosylase associated protein TTRAP PF14203.6 EGD87202.1 - 0.014 15.4 2.6 0.054 13.5 0.2 3.1 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein DCB PF16213.5 EGD87202.1 - 0.04 13.6 4.2 5.1 6.7 0.1 3.9 4 0 0 4 4 4 0 Dimerisation and cyclophilin-binding domain of Mon2 eIF-5_eIF-2B PF01873.17 EGD87203.1 - 4.8e-39 132.8 0.0 8.5e-39 132.1 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EGD87203.1 - 1.6e-21 76.2 0.4 1.6e-21 76.2 0.4 2.4 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon PcfK PF14058.6 EGD87203.1 - 0.21 11.9 0.0 0.21 11.9 0.0 3.0 3 0 0 3 3 3 0 PcfK-like protein HK PF02110.15 EGD87204.1 - 6.4e-77 258.3 0.1 6.4e-77 258.3 0.1 1.6 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EGD87204.1 - 1.3e-58 197.4 3.3 2.2e-58 196.6 3.3 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase QRPTase_C PF01729.19 EGD87204.1 - 0.0029 17.4 0.0 0.0067 16.2 0.0 1.6 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain PfkB PF00294.24 EGD87204.1 - 0.0047 16.3 0.0 0.0088 15.4 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase NMO PF03060.15 EGD87204.1 - 0.55 9.6 7.4 0.22 10.9 3.8 2.1 2 1 0 2 2 2 0 Nitronate monooxygenase Isochorismatase PF00857.20 EGD87205.1 - 3.2e-27 95.8 0.0 4.1e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.6 EGD87209.2 - 1.1e-21 78.1 0.0 2.1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGD87209.2 - 9e-18 65.0 0.0 1.2e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Voltage_CLC PF00654.20 EGD87211.1 - 1.5e-90 304.0 24.3 2.2e-90 303.5 20.2 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel KCNQC3-Ank-G_bd PF11956.8 EGD87211.1 - 0.074 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 DHFR_1 PF00186.19 EGD87212.1 - 7.1e-18 64.8 0.1 1.4e-08 34.6 0.0 3.3 2 1 1 3 3 3 3 Dihydrofolate reductase Med22 PF06179.12 EGD87213.1 - 1.5e-20 73.3 2.6 1.8e-20 73.1 2.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF2225 PF09986.9 EGD87213.1 - 0.12 12.1 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) PrmC_N PF17827.1 EGD87213.1 - 0.19 12.3 3.3 1.7 9.2 3.3 2.1 1 1 0 1 1 1 0 PrmC N-terminal domain Cwf_Cwc_15 PF04889.12 EGD87215.1 - 6e-88 294.7 16.6 6.9e-88 294.5 16.6 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3752 PF12572.8 EGD87215.1 - 0.027 15.0 14.4 0.035 14.6 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) MFAP1 PF06991.11 EGD87215.1 - 0.032 14.1 14.6 0.046 13.6 14.6 1.5 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing DUF4636 PF15468.6 EGD87215.1 - 0.5 10.0 3.8 0.72 9.5 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) PA26 PF04636.13 EGD87215.1 - 1.7 7.5 4.2 2 7.3 4.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Phostensin_N PF13916.6 EGD87215.1 - 4.4 7.7 12.0 10 6.5 7.0 2.4 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Hid1 PF12722.7 EGD87215.1 - 5.4 5.0 6.2 6.1 4.8 6.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Roughex PF06020.11 EGD87215.1 - 7.8 5.5 15.6 10 5.1 15.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein ICMT PF04140.14 EGD87218.1 - 1.2e-29 102.6 0.2 1.2e-29 102.6 0.2 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGD87218.1 - 3.9e-11 43.3 2.3 3.9e-11 43.3 2.3 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 EGD87218.1 - 1.7e-05 24.5 0.4 2.9e-05 23.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Neugrin PF06413.11 EGD87219.1 - 2.9e-09 37.3 2.9 6e-09 36.2 2.6 1.7 1 1 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 EGD87219.1 - 5.2e-08 33.2 5.6 5.2e-08 33.2 5.6 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_DeoR PF08220.12 EGD87219.1 - 0.04 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain BTG PF07742.12 EGD87219.1 - 0.045 13.6 0.2 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 BTG family HTH_7 PF02796.15 EGD87219.1 - 0.12 12.5 0.4 0.68 10.1 0.0 2.5 3 1 0 3 3 3 0 Helix-turn-helix domain of resolvase Rgp1 PF08737.10 EGD87220.2 - 2.3e-65 221.4 0.1 2.3e-65 221.4 0.1 2.1 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.29 EGD87220.2 - 1.5e-05 25.1 0.1 4.3e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGD87220.2 - 0.082 13.4 1.2 0.39 11.2 0.0 2.5 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Mob1_phocein PF03637.17 EGD87221.1 - 4.4e-72 241.6 0.1 5.5e-72 241.3 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.18 EGD87222.2 - 2.2e-45 154.9 1.7 3e-45 154.4 1.7 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit ATG16 PF08614.11 EGD87223.1 - 0.0043 17.3 0.6 0.0043 17.3 0.6 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) K-box PF01486.17 EGD87223.1 - 0.033 14.3 0.1 0.048 13.8 0.1 1.3 1 0 0 1 1 1 0 K-box region Sugarporin_N PF11471.8 EGD87223.1 - 0.087 12.8 4.0 0.17 11.8 4.0 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Bromodomain PF00439.25 EGD87224.1 - 1.3e-06 28.3 0.0 0.00021 21.3 0.0 2.4 2 0 0 2 2 2 2 Bromodomain Diphthamide_syn PF01866.17 EGD87225.2 - 3.3e-118 394.6 0.0 4.1e-118 394.3 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HMGL-like PF00682.19 EGD87226.1 - 1e-43 149.8 0.0 1.2e-43 149.6 0.0 1.0 1 0 0 1 1 1 1 HMGL-like PE PF00934.20 EGD87226.1 - 0.29 11.5 1.6 0.45 10.9 0.3 2.1 2 1 0 2 2 2 0 PE family DUF1674 PF07896.12 EGD87227.1 - 1.2e-20 73.7 3.8 1.2e-20 73.7 3.8 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) MSA_2 PF00985.17 EGD87227.1 - 0.13 12.6 2.4 0.16 12.4 2.4 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Aminotran_3 PF00202.21 EGD87228.1 - 2.4e-112 375.6 0.0 3.1e-112 375.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGD87228.1 - 8.1e-05 22.0 0.0 0.00043 19.6 0.0 1.8 1 1 1 2 2 2 1 Aminotransferase class I and II DUF4719 PF15843.5 EGD87231.1 - 0.08 13.0 4.8 0.052 13.7 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) Rxt3 PF08642.10 EGD87232.2 - 9.1e-46 155.8 2.2 2.8e-45 154.2 0.0 2.5 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 EGD87232.2 - 0.00024 21.2 0.0 0.0037 17.3 0.0 2.4 2 0 0 2 2 2 1 LCCL domain Carn_acyltransf PF00755.20 EGD87233.2 - 2.5e-209 696.7 0.0 2.9e-209 696.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase TMCO5 PF14992.6 EGD87234.1 - 0.0079 15.8 0.5 0.017 14.7 0.5 1.6 1 1 0 1 1 1 1 TMCO5 family DUF2046 PF09755.9 EGD87234.1 - 0.01 15.1 2.1 0.041 13.1 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Jnk-SapK_ap_N PF09744.9 EGD87234.1 - 0.047 13.9 6.7 0.35 11.1 0.3 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 LRRFIP PF09738.9 EGD87234.1 - 0.067 12.7 0.2 0.067 12.7 0.2 3.5 2 2 1 4 4 3 0 LRRFIP family SlyX PF04102.12 EGD87234.1 - 0.14 12.8 8.6 3 8.5 2.9 2.5 2 0 0 2 2 2 0 SlyX Cnn_1N PF07989.11 EGD87234.1 - 0.28 11.4 0.0 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF3450 PF11932.8 EGD87234.1 - 0.46 9.8 9.8 0.37 10.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2968 PF11180.8 EGD87234.1 - 0.92 9.1 13.7 0.23 11.1 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Siah-Interact_N PF09032.11 EGD87234.1 - 0.94 9.8 7.0 0.29 11.4 2.0 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal Fib_alpha PF08702.10 EGD87234.1 - 0.97 9.6 5.7 2.6 8.2 0.3 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 EGD87234.1 - 1.5 7.8 9.0 2.4 7.2 3.9 2.6 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GIT_CC PF16559.5 EGD87234.1 - 1.7 8.6 13.5 2.9 7.8 1.0 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Uso1_p115_C PF04871.13 EGD87234.1 - 4.1 7.8 8.9 20 5.6 3.4 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3138 PF11336.8 EGD87234.1 - 5.8 5.4 8.8 0.91 8.1 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Lectin_C PF00059.21 EGD87236.1 - 0.00018 22.2 1.9 0.0005 20.8 0.3 2.3 2 0 0 2 2 2 1 Lectin C-type domain Sec62 PF03839.16 EGD87237.1 - 9.8e-74 247.5 0.5 9.8e-74 247.5 0.5 2.6 2 1 1 3 3 3 1 Translocation protein Sec62 Zip PF02535.22 EGD87237.1 - 0.00018 20.9 0.1 0.32 10.2 0.0 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter Ribosomal_L20 PF00453.18 EGD87237.1 - 0.85 9.7 5.1 0.93 9.6 1.0 2.6 3 0 0 3 3 3 0 Ribosomal protein L20 DUF4834 PF16118.5 EGD87237.1 - 1.3 10.0 12.0 16 6.5 0.0 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 EGD87237.1 - 1.6 8.7 9.8 39 4.2 8.5 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Cupin_1 PF00190.22 EGD87242.2 - 9.8e-30 103.2 0.0 5.6e-17 61.7 0.0 2.3 2 1 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EGD87242.2 - 4.1e-18 64.9 0.3 6.2e-11 41.9 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EGD87242.2 - 7.8e-06 25.5 0.1 0.0065 16.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AAA_10 PF12846.7 EGD87244.2 - 0.012 14.6 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ClpB_D2-small PF10431.9 EGD87244.2 - 0.02 14.9 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 EGD87244.2 - 0.036 14.5 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 EGD87244.2 - 0.059 12.5 0.1 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 EGD87244.2 - 0.15 11.6 0.1 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region SNAP PF14938.6 EGD87245.2 - 6.7e-110 367.0 20.9 7.9e-110 366.7 20.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EGD87245.2 - 3.1e-08 33.8 8.4 0.00076 19.7 0.2 3.8 2 1 1 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGD87245.2 - 3.9e-05 23.4 12.2 0.7 10.1 0.1 6.1 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGD87245.2 - 0.0041 17.0 4.2 22 5.4 0.0 5.6 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGD87245.2 - 0.046 14.0 15.8 1.4 9.3 0.1 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat NigD_N PF12667.7 EGD87245.2 - 0.1 12.7 0.0 3 8.0 0.0 2.8 2 0 0 2 2 2 0 NigD-like N-terminal OB domain NSF PF02071.20 EGD87245.2 - 0.17 12.7 0.4 0.17 12.7 0.4 6.0 6 0 0 6 6 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_16 PF13432.6 EGD87245.2 - 0.23 12.1 15.1 5.9 7.6 3.4 4.5 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGD87245.2 - 0.27 11.1 15.3 3.2 7.7 1.0 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat CBP PF12192.8 EGD87245.2 - 0.31 11.3 0.1 0.31 11.3 0.1 2.2 2 1 0 2 2 2 0 Fungal calcium binding protein MIT PF04212.18 EGD87245.2 - 0.4 10.8 7.5 18 5.5 0.2 4.8 2 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EGD87245.2 - 0.49 11.1 16.6 5 8.0 0.1 5.6 7 0 0 7 7 5 0 Tetratricopeptide repeat HlyIII PF03006.20 EGD87247.2 - 2.7e-53 181.0 17.6 3.3e-53 180.7 17.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related ATP-synt_8 PF00895.20 EGD87247.2 - 0.46 11.0 4.7 0.47 11.0 0.2 2.4 2 0 0 2 2 2 0 ATP synthase protein 8 RIBIOP_C PF04950.12 EGD87248.2 - 2.2e-109 365.4 0.0 6.9e-109 363.8 0.0 1.9 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGD87248.2 - 3.5e-22 78.3 0.0 7.9e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain BING4CT PF08149.11 EGD87249.2 - 3e-40 135.9 0.3 4.4e-36 122.5 0.0 2.9 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EGD87249.2 - 7.2e-07 29.4 0.0 0.62 10.4 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGD87249.2 - 2.3e-05 25.1 0.4 0.24 12.3 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF4427 PF14468.6 EGD87249.2 - 0.014 15.5 0.5 0.053 13.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4427) CHASE3 PF05227.13 EGD87249.2 - 0.046 13.6 4.2 0.076 12.9 4.2 1.4 1 0 0 1 1 1 0 CHASE3 domain cobW PF02492.19 EGD87250.1 - 5e-33 114.2 0.0 6.2e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EGD87250.1 - 8.5e-06 24.9 0.0 0.0042 16.1 0.1 2.0 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EGD87250.1 - 0.0026 18.3 0.0 0.0038 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGD87250.1 - 0.004 17.2 0.0 0.0082 16.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EGD87250.1 - 0.046 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PRK PF00485.18 EGD87250.1 - 0.15 11.8 0.0 0.47 10.2 0.0 1.9 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EGD87250.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EGD87250.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 EGD87250.1 - 0.17 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LIM_bind PF01803.16 EGD87251.2 - 1.7e-49 168.5 0.0 1.7e-49 168.5 0.0 3.9 2 1 0 3 3 3 1 LIM-domain binding protein DUF1764 PF08576.10 EGD87251.2 - 8.8 7.3 11.3 25 5.8 1.9 3.0 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) AAA PF00004.29 EGD87252.1 - 8.4e-39 133.0 0.0 1.1e-37 129.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD87252.1 - 3e-09 36.5 0.0 8.8e-09 35.0 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGD87252.1 - 9.3e-05 22.9 0.7 0.001 19.5 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGD87252.1 - 0.00014 21.6 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGD87252.1 - 0.00022 21.5 0.1 0.018 15.3 0.0 2.7 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 EGD87252.1 - 0.00043 19.6 0.0 0.00084 18.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGD87252.1 - 0.0005 20.2 0.0 0.0037 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGD87252.1 - 0.00066 19.7 0.0 0.0031 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGD87252.1 - 0.0043 16.5 0.1 0.01 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGD87252.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 EGD87252.1 - 0.014 15.5 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGD87252.1 - 0.017 15.7 0.0 0.094 13.3 0.0 2.3 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 EGD87252.1 - 0.024 15.0 0.0 0.065 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 EGD87252.1 - 0.025 14.8 0.0 0.082 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGD87252.1 - 0.031 14.0 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4337 PF14235.6 EGD87252.1 - 0.044 13.9 0.2 0.13 12.4 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4337) TniB PF05621.11 EGD87252.1 - 0.066 12.6 0.0 0.31 10.4 0.0 2.1 3 0 0 3 3 3 0 Bacterial TniB protein AAA_17 PF13207.6 EGD87252.1 - 0.07 13.5 0.1 0.25 11.8 0.1 2.0 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGD87252.1 - 0.076 13.0 0.1 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 EGD87252.1 - 0.13 12.4 0.0 0.96 9.5 0.0 2.4 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) IPT PF01745.16 EGD87252.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase NACHT PF05729.12 EGD87252.1 - 0.15 12.0 0.2 0.43 10.5 0.1 1.8 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 EGD87252.1 - 0.17 11.6 0.2 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Pkinase PF00069.25 EGD87253.1 - 1e-14 54.6 0.0 1.6e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87253.1 - 8.2e-08 31.8 0.0 3.6e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase TPR_12 PF13424.6 EGD87254.2 - 0.0072 16.6 3.2 6.7 7.1 0.1 4.1 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGD87254.2 - 0.085 13.4 6.9 9.3 6.8 1.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4050 PF13259.6 EGD87256.2 - 5.3e-57 193.1 1.7 5.3e-57 193.1 1.7 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF4050) Mus7 PF09462.10 EGD87257.1 - 9.6e-159 530.1 0.0 1.3e-158 529.7 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family PAPA-1 PF04795.12 EGD87259.1 - 8e-32 109.9 5.6 8e-32 109.9 5.6 3.2 3 0 0 3 3 3 1 PAPA-1-like conserved region Pex14_N PF04695.13 EGD87260.1 - 1.2e-42 146.2 3.2 1.2e-42 146.2 3.2 2.4 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Calcipressin PF04847.12 EGD87261.1 - 3.2e-33 115.0 0.3 7.4e-33 113.9 0.3 1.5 1 1 0 1 1 1 1 Calcipressin Uds1 PF15456.6 EGD87265.1 - 1.1e-28 100.0 3.7 2.8e-28 98.7 3.7 1.7 1 0 0 1 1 1 1 Up-regulated During Septation Stathmin PF00836.19 EGD87265.1 - 0.013 15.4 1.3 0.036 14.0 0.3 2.2 2 0 0 2 2 2 0 Stathmin family GrpE PF01025.19 EGD87266.1 - 3.9e-42 143.7 2.6 5.6e-42 143.2 2.6 1.2 1 0 0 1 1 1 1 GrpE PEARLI-4 PF05278.12 EGD87266.1 - 0.032 13.8 1.9 0.05 13.2 1.9 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4201 PF13870.6 EGD87266.1 - 0.036 13.8 0.3 0.056 13.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) TPD52 PF04201.15 EGD87266.1 - 0.076 12.6 0.8 0.12 12.0 0.7 1.5 1 1 0 1 1 1 0 Tumour protein D52 family HIP1_clath_bdg PF16515.5 EGD87266.1 - 0.2 12.3 3.0 1.4 9.5 1.5 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HSCB_C PF07743.13 EGD87266.1 - 2.6 8.6 7.3 8.5 7.0 5.0 2.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain MDMPI_N PF11716.8 EGD87266.1 - 6.9 7.3 6.6 21 5.8 6.6 1.8 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Mito_carr PF00153.27 EGD87268.2 - 1.9e-58 194.4 0.0 2.1e-19 69.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein COX6B PF02297.17 EGD87269.2 - 1.9e-19 69.6 7.1 2.3e-19 69.4 7.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 EGD87269.2 - 0.04 13.9 2.3 0.045 13.7 1.7 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain CHCH PF06747.13 EGD87269.2 - 0.041 14.0 1.2 0.11 12.7 1.2 1.7 1 1 0 1 1 1 0 CHCH domain CX9C PF16860.5 EGD87269.2 - 0.051 13.6 4.1 0.059 13.4 3.1 1.6 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, B12D PF06522.11 EGD87270.1 - 0.0042 16.8 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.22 EGD87271.2 - 5.3e-12 45.4 0.0 7.1e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGD87271.2 - 0.026 14.6 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif Transp_cyt_pur PF02133.15 EGD87274.1 - 2.6e-10 39.7 18.6 3.5e-10 39.3 18.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ATE_C PF04377.15 EGD87275.2 - 2.1e-31 109.3 4.8 9.7e-31 107.2 4.8 2.0 1 1 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EGD87275.2 - 1.2e-23 83.3 4.2 3.6e-23 81.7 4.2 1.9 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Glutaredoxin PF00462.24 EGD87275.2 - 0.034 14.4 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin NUDIX PF00293.28 EGD87276.1 - 1.4e-18 67.2 0.2 1.7e-18 66.9 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain RNA_pol_A_bac PF01000.26 EGD87277.1 - 1.7e-30 105.6 0.0 2.6e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGD87277.1 - 2.1e-14 52.7 0.0 2.7e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Baculo_PEP_C PF04513.12 EGD87278.1 - 0.1 12.6 5.4 1 9.4 0.4 2.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_C PF00034.21 EGD87280.2 - 1.4e-10 42.2 0.0 2.7e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGD87280.2 - 2.2e-07 31.1 1.5 1.4e-06 28.5 1.5 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III BPS1 PF05633.11 EGD87280.2 - 0.011 14.7 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related CCP_MauG PF03150.14 EGD87280.2 - 0.015 16.0 0.0 0.025 15.2 0.0 1.5 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrom_C550 PF14495.6 EGD87280.2 - 0.032 13.9 0.1 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c-550 domain Subtilosin_A PF11420.8 EGD87280.2 - 8.1 6.5 6.5 0.7 9.9 0.3 2.4 3 0 0 3 3 3 0 Bacteriocin subtilosin A RNase_PH PF01138.21 EGD87282.1 - 1.3e-13 51.6 0.0 4.5e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGD87282.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 HHH PF00633.23 EGD87283.2 - 0.057 13.3 0.6 8.9 6.4 0.0 3.2 3 0 0 3 3 3 0 Helix-hairpin-helix motif Metallophos PF00149.28 EGD87284.1 - 2.7e-08 34.6 0.2 3.6e-08 34.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGD87284.1 - 0.019 15.2 0.0 0.17 12.1 0.0 2.1 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Inv-AAD PF18785.1 EGD87285.1 - 3.5e-46 156.3 0.1 6.1e-46 155.5 0.1 1.3 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EGD87285.1 - 3.2e-09 36.6 0.0 3.5e-08 33.2 0.0 2.4 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 EGD87285.1 - 2.4e-06 27.5 0.0 5e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 EGD87285.1 - 0.063 13.4 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 SNAD4 PF18750.1 EGD87285.1 - 0.077 13.1 0.1 0.22 11.7 0.1 1.8 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Stn1 PF10451.9 EGD87288.1 - 1.6e-13 50.2 0.1 2.2e-12 46.5 0.1 2.0 1 1 0 1 1 1 1 Telomere regulation protein Stn1 SelP_N PF04592.14 EGD87289.1 - 1.3 8.3 13.6 2.4 7.5 13.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Abhydrolase_1 PF00561.20 EGD87290.2 - 9.1e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD87290.2 - 0.0055 17.3 0.1 0.0078 16.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family F-box-like PF12937.7 EGD87291.1 - 7e-05 22.7 0.2 0.00025 20.9 0.2 2.0 1 0 0 1 1 1 1 F-box-like APH PF01636.23 EGD87292.1 - 1.3e-09 38.3 0.0 1.3e-07 31.8 0.0 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family EcKinase PF02958.20 EGD87292.1 - 0.085 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase F-box-like PF12937.7 EGD87294.2 - 7.2e-05 22.6 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like SH3-WW_linker PF16618.5 EGD87294.2 - 0.00071 20.1 0.1 0.0015 19.1 0.1 1.5 2 0 0 2 2 2 1 Linker region between SH3 and WW domains on ARHGAP12 Pkinase PF00069.25 EGD87298.1 - 1.3e-57 195.1 0.0 3.9e-57 193.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87298.1 - 1.1e-32 113.4 0.0 1e-31 110.2 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGD87298.1 - 0.00045 19.3 0.0 0.001 18.1 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EGD87298.1 - 0.079 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BEN PF10523.9 EGD87300.1 - 0.17 12.2 0.1 14 6.0 0.0 3.0 2 1 1 3 3 3 0 BEN domain DnaJ PF00226.31 EGD87301.1 - 7.8e-22 77.2 0.6 7.8e-22 77.2 0.6 1.9 2 0 0 2 2 2 1 DnaJ domain Usp PF00582.26 EGD87302.1 - 8.2e-22 78.2 0.6 1.8e-14 54.4 0.3 2.8 2 0 0 2 2 2 2 Universal stress protein family DUF3716 PF12511.8 EGD87304.2 - 0.00014 21.8 0.2 0.00021 21.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Peptidase_S10 PF00450.22 EGD87307.2 - 4.7e-46 158.0 0.0 9e-46 157.1 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase GCK PF07802.11 EGD87307.2 - 0.061 13.8 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 GCK domain ATP-synt_ab PF00006.25 EGD87308.1 - 7.4e-68 228.4 0.0 1e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGD87308.1 - 3.5e-12 46.7 0.7 7.2e-12 45.6 0.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5305 PF17231.2 EGD87309.1 - 0.0081 15.6 0.1 0.035 13.5 0.0 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5305) Adeno_E3_CR2 PF02439.15 EGD87309.1 - 0.025 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gram_pos_anchor PF00746.21 EGD87309.1 - 0.094 12.7 0.2 0.22 11.5 0.2 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif QWRF PF04484.12 EGD87309.1 - 4.2 7.0 7.0 1 9.0 2.9 1.7 1 1 1 2 2 2 0 QWRF family Trp_syntA PF00290.20 EGD87310.1 - 2.8e-93 311.5 0.0 4.9e-93 310.7 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EGD87310.1 - 1.3e-47 162.7 2.3 2.2e-47 161.9 2.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TIG PF01833.24 EGD87311.2 - 0.38 10.9 5.2 0.2 11.8 0.6 2.5 2 0 0 2 2 2 0 IPT/TIG domain ADH_zinc_N PF00107.26 EGD87314.1 - 2.4e-23 82.6 1.0 3.5e-23 82.0 1.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGD87314.1 - 2.2e-09 38.5 0.0 4.9e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGD87314.1 - 4.8e-05 23.2 0.0 9.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EGD87314.1 - 0.02 14.2 1.3 0.034 13.4 1.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EGD87314.1 - 0.049 13.1 1.8 0.11 11.9 0.7 2.2 2 1 1 3 3 3 0 short chain dehydrogenase APH PF01636.23 EGD87315.2 - 8.3e-11 42.3 0.0 5.1e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGD87315.2 - 0.07 12.5 0.0 23 4.2 0.0 3.0 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family HNH_2 PF13391.6 EGD87319.2 - 8.5e-15 54.7 0.2 6e-14 51.9 0.0 2.5 1 1 1 2 2 2 1 HNH endonuclease GYF PF02213.16 EGD87321.1 - 3.1e-16 58.8 2.3 4e-16 58.4 0.4 2.3 2 0 0 2 2 2 1 GYF domain B12D PF06522.11 EGD87321.1 - 0.037 13.8 0.9 0.14 12.0 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit GYF_2 PF14237.6 EGD87321.1 - 0.16 11.8 0.3 0.44 10.4 0.3 1.8 1 0 0 1 1 1 0 GYF domain 2 Homeodomain PF00046.29 EGD87321.1 - 0.42 10.5 3.7 1.4 8.8 3.7 1.9 1 0 0 1 1 1 0 Homeodomain Aminotran_5 PF00266.19 EGD87322.2 - 0.00013 21.0 0.0 0.00017 20.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DUF577 PF04510.12 EGD87322.2 - 0.026 14.4 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF577) CTNNBL PF08216.11 EGD87322.2 - 0.17 12.1 0.1 0.41 10.8 0.0 1.6 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear zf-RING_2 PF13639.6 EGD87323.2 - 3.8e-13 49.5 21.2 3.8e-13 49.5 9.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EGD87323.2 - 3.3e-11 42.7 8.3 1.1e-10 41.0 3.9 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGD87323.2 - 3.3e-09 36.4 9.1 3.3e-09 36.4 9.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGD87323.2 - 5.6e-09 35.7 11.8 1.2e-07 31.4 4.6 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGD87323.2 - 2.5e-07 30.9 7.8 2.5e-07 30.9 7.8 2.4 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGD87323.2 - 3.3e-07 30.1 18.1 5.6e-07 29.3 8.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGD87323.2 - 4.2e-07 29.8 6.1 4.2e-07 29.8 6.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zinc_ribbon_9 PF14369.6 EGD87323.2 - 1.9e-06 28.0 10.4 0.00014 22.0 5.1 2.5 2 0 0 2 2 2 2 zinc-ribbon Prok-RING_4 PF14447.6 EGD87323.2 - 1.3e-05 24.9 14.3 0.00036 20.3 5.0 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGD87323.2 - 2.5e-05 24.2 3.1 2.5e-05 24.2 3.1 2.6 2 0 0 2 2 2 1 RING-type zinc-finger HypA PF01155.19 EGD87323.2 - 0.00038 20.5 6.5 0.0012 18.9 0.3 2.3 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ANAPC11 PF12861.7 EGD87323.2 - 0.00061 19.8 2.9 0.00061 19.8 2.9 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGD87323.2 - 0.004 16.8 6.7 0.004 16.8 6.7 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EGD87323.2 - 0.051 13.7 13.3 1.6 9.0 6.0 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.7 EGD87323.2 - 0.053 13.6 8.7 0.067 13.2 0.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon Baculo_RING PF05883.11 EGD87323.2 - 0.12 12.3 3.0 0.24 11.4 0.4 2.1 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.6 EGD87323.2 - 0.16 11.8 14.3 0.24 11.2 5.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EGD87323.2 - 0.32 10.9 2.4 1.1 9.1 2.4 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 EGD87323.2 - 0.75 9.7 14.6 0.63 10.0 7.5 2.6 2 0 0 2 2 2 0 PHD-finger zinc-ribbons_6 PF07191.12 EGD87323.2 - 0.79 9.7 11.7 0.42 10.6 1.0 2.6 2 1 0 2 2 2 0 zinc-ribbons UPF0547 PF10571.9 EGD87323.2 - 2.4 8.3 9.7 4.3 7.5 0.2 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DUF1272 PF06906.11 EGD87323.2 - 3.2 7.9 9.9 10 6.3 3.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) FANCL_C PF11793.8 EGD87323.2 - 5.4 7.3 11.8 1.8 8.8 7.3 2.5 2 1 0 2 2 1 0 FANCL C-terminal domain Fis1_TPR_C PF14853.6 EGD87324.1 - 6.4e-26 90.2 0.4 1e-25 89.5 0.4 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EGD87324.1 - 7.5e-17 60.7 0.0 1.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EGD87324.1 - 0.0011 18.9 1.6 0.0026 17.7 1.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF2957 PF11170.8 EGD87324.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) TPR_1 PF00515.28 EGD87324.1 - 0.12 12.2 2.4 0.26 11.2 2.4 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.11 EGD87325.1 - 2.6e-39 133.7 3.2 9.2e-38 128.7 0.2 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 MAP65_ASE1 PF03999.12 EGD87325.1 - 0.0032 16.3 3.1 0.0035 16.1 3.1 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) APG6_N PF17675.1 EGD87325.1 - 0.0032 18.0 11.4 0.0044 17.5 11.4 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region FlaC_arch PF05377.11 EGD87325.1 - 0.017 15.5 2.9 0.79 10.2 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) WXG100 PF06013.12 EGD87325.1 - 0.02 15.1 3.0 0.18 12.0 0.2 2.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Syntaxin PF00804.25 EGD87325.1 - 0.023 14.4 3.0 0.045 13.4 3.0 1.5 1 0 0 1 1 1 0 Syntaxin FlxA PF14282.6 EGD87325.1 - 0.034 14.1 2.6 2.2 8.3 0.1 2.2 2 0 0 2 2 2 0 FlxA-like protein Spc7 PF08317.11 EGD87325.1 - 0.04 12.8 8.4 0.053 12.4 8.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CLZ PF16526.5 EGD87325.1 - 0.059 13.7 8.8 0.2 12.0 1.5 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4472 PF14739.6 EGD87325.1 - 0.074 13.8 1.7 0.074 13.8 1.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF4795 PF16043.5 EGD87325.1 - 0.087 12.4 4.7 0.49 10.0 4.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Streptin-Immun PF11083.8 EGD87325.1 - 0.087 13.2 1.0 0.31 11.5 0.1 2.0 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF4337 PF14235.6 EGD87325.1 - 0.1 12.7 3.9 0.13 12.3 2.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Prefoldin_2 PF01920.20 EGD87325.1 - 0.1 12.5 6.3 0.66 10.0 1.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.19 EGD87325.1 - 0.14 10.1 1.2 0.14 10.0 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5344 PF17279.2 EGD87325.1 - 0.2 12.2 3.1 4.2 8.0 0.1 2.6 3 0 0 3 3 2 0 Family of unknown function (DUF5344) FapA PF03961.13 EGD87325.1 - 0.21 10.1 2.0 0.25 9.9 2.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DHR10 PF18595.1 EGD87325.1 - 0.27 11.3 14.2 1.1 9.3 14.2 1.9 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain EAP30 PF04157.16 EGD87325.1 - 0.28 10.4 5.6 19 4.5 5.6 2.1 1 1 0 1 1 1 0 EAP30/Vps36 family YlqD PF11068.8 EGD87325.1 - 0.49 10.8 4.4 0.76 10.1 4.4 1.3 1 0 0 1 1 1 0 YlqD protein Phage_GPO PF05929.11 EGD87325.1 - 0.54 9.8 5.8 2.4 7.7 5.8 1.9 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Swi5 PF07061.11 EGD87325.1 - 0.61 10.2 3.9 9.4 6.4 0.4 2.4 2 0 0 2 2 2 0 Swi5 Ribosomal_L29 PF00831.23 EGD87325.1 - 0.65 10.0 6.9 2.2 8.3 0.5 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein SlyX PF04102.12 EGD87325.1 - 1 10.0 7.8 1.8 9.2 1.1 2.5 2 1 0 2 2 2 0 SlyX DUF2937 PF11157.8 EGD87325.1 - 1 9.1 4.1 0.82 9.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Csm1_N PF18504.1 EGD87325.1 - 1.1 9.7 6.8 6.8 7.1 0.9 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain YabA PF06156.13 EGD87325.1 - 1.2 9.8 4.4 21 5.8 0.3 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Viral_P18 PF04521.13 EGD87325.1 - 2.2 8.1 6.2 6.2 6.6 1.0 2.4 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF1690 PF07956.11 EGD87325.1 - 4.9 7.6 9.7 14 6.0 9.7 1.7 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DASH_Hsk3 PF08227.11 EGD87325.1 - 5.3 7.5 9.4 3 8.3 0.8 2.7 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like DUF4140 PF13600.6 EGD87325.1 - 6.1 7.3 9.1 10 6.6 2.5 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 EGD87325.1 - 9.7 5.4 9.2 18 4.5 9.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3431 PF11913.8 EGD87326.2 - 2.1e-62 210.7 0.0 2.9e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) MbtH PF03621.13 EGD87326.2 - 0.073 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 MbtH-like protein DUF2034 PF10356.9 EGD87327.1 - 1.6e-37 128.7 0.0 3.6e-21 75.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EGD87327.1 - 8.8e-07 29.0 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.8 EGD87328.1 - 6.9e-53 178.8 22.1 1.5e-50 171.2 22.1 2.0 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med26_C PF15693.5 EGD87328.1 - 0.023 14.9 5.4 0.028 14.6 5.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal TFIIA PF03153.13 EGD87328.1 - 0.026 14.5 14.1 0.03 14.3 14.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EGD87328.1 - 0.032 13.8 12.4 0.04 13.5 12.4 1.2 1 0 0 1 1 1 0 Spt20 family DUF4194 PF13835.6 EGD87328.1 - 0.047 13.4 2.1 0.066 12.9 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) DUF4175 PF13779.6 EGD87328.1 - 0.051 11.5 18.6 0.071 11.0 18.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spore_III_AB PF09548.10 EGD87328.1 - 0.14 12.3 3.8 0.21 11.7 3.8 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PMC2NT PF08066.12 EGD87328.1 - 0.17 12.6 0.2 0.6 10.8 0.0 1.9 2 0 0 2 2 2 0 PMC2NT (NUC016) domain NINJA_B PF16136.5 EGD87328.1 - 0.42 11.0 10.8 2 8.8 2.6 2.2 2 0 0 2 2 2 0 Putative nuclear localisation signal Suf PF05843.14 EGD87328.1 - 1 9.3 6.7 1.3 9.0 6.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 EGD87328.1 - 7.9 5.0 6.4 8.3 5.0 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SNF2_N PF00176.23 EGD87329.2 - 6.8e-65 219.1 0.0 9.9e-65 218.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGD87329.2 - 6e-12 45.9 0.0 3.9e-11 43.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGD87329.2 - 1e-05 25.3 0.0 3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 EGD87329.2 - 0.016 15.1 1.8 0.041 13.8 1.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF896 PF05979.12 EGD87329.2 - 1.9 8.4 7.1 34 4.4 0.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) PI3_PI4_kinase PF00454.27 EGD87330.1 - 5.1e-45 154.2 0.0 8.3e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF1658 PF07871.11 EGD87330.1 - 0.035 14.0 2.0 6 7.0 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) EF-hand_1 PF00036.32 EGD87330.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 EF hand GATA PF00320.27 EGD87332.2 - 8.3e-16 57.3 2.5 8.3e-16 57.3 2.5 1.6 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EGD87332.2 - 0.012 15.1 2.6 0.012 15.1 0.4 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding ArfGap PF01412.18 EGD87332.2 - 0.022 14.8 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 EGD87332.2 - 0.034 14.3 0.8 0.068 13.3 0.8 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 EGD87332.2 - 0.047 13.6 0.3 0.093 12.6 0.3 1.5 1 0 0 1 1 1 0 Domain found in IF2B/IF5 DUF2387 PF09526.10 EGD87332.2 - 0.091 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.10 EGD87332.2 - 0.31 11.2 0.2 0.31 11.2 0.2 2.3 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.7 EGD87332.2 - 0.87 9.7 5.5 1.4 9.0 1.6 2.6 2 2 1 3 3 3 0 Double zinc ribbon Nodulin-like PF06813.13 EGD87333.2 - 2.2e-21 76.5 4.5 3.5e-21 75.8 4.5 1.2 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 EGD87333.2 - 2.5e-12 46.4 15.5 2.5e-12 46.4 15.5 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD87333.2 - 0.41 9.4 13.7 0.65 8.8 12.1 2.1 2 1 1 3 3 3 0 Sugar (and other) transporter Serinc PF03348.15 EGD87334.2 - 5e-153 510.1 9.4 5.6e-153 509.9 9.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) YqhR PF11085.8 EGD87334.2 - 0.34 10.8 13.8 0.043 13.7 6.7 2.7 2 0 0 2 2 2 0 Conserved membrane protein YqhR DUF4148 PF13663.6 EGD87334.2 - 1.3 9.2 5.9 0.24 11.6 0.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) DNA_mis_repair PF01119.19 EGD87335.1 - 2.1e-20 72.6 0.0 3.1e-19 68.8 0.0 2.5 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 EGD87335.1 - 8.6e-19 67.8 3.2 8.7e-16 58.0 1.4 3.3 3 1 0 3 3 3 2 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EGD87335.1 - 0.0001 22.2 0.0 0.00028 20.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GCN5L1 PF06320.13 EGD87336.1 - 3.7e-17 62.5 2.0 3.7e-17 62.5 2.0 1.3 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) DUF3552 PF12072.8 EGD87336.1 - 0.032 13.7 4.3 0.023 14.1 3.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2570 PF10828.8 EGD87336.1 - 0.068 13.0 0.6 0.1 12.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF630 PF04783.12 EGD87336.1 - 0.1 12.8 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF630) DivIC PF04977.15 EGD87336.1 - 0.28 11.0 2.6 0.51 10.1 2.6 1.4 1 0 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 EGD87336.1 - 1.4 9.5 8.8 2.2 8.8 8.8 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 EGD87336.1 - 2.6 8.6 6.7 1.6e+02 3.0 6.7 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FTA2 PF13095.6 EGD87339.2 - 1.8e-42 145.4 0.0 7.9e-40 136.8 0.0 2.8 2 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGD87339.2 - 0.049 13.5 0.0 0.088 12.7 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 EGD87340.2 - 8.8e-06 26.4 0.0 1.3 10.0 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat SPO22 PF08631.10 EGD87341.2 - 1.8e-16 60.4 4.1 2e-16 60.3 1.7 2.1 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like APH PF01636.23 EGD87344.1 - 3.6e-20 72.9 0.0 3.8e-19 69.6 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGD87344.1 - 2e-05 23.7 0.1 0.026 13.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.20 EGD87344.1 - 0.00061 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 EGD87344.1 - 0.0027 16.9 0.0 0.068 12.4 0.0 2.1 2 0 0 2 2 2 1 Fructosamine kinase Pkinase PF00069.25 EGD87344.1 - 0.03 13.7 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.22 EGD87344.1 - 0.16 11.5 0.1 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 RIO1 family BTRD1 PF17660.1 EGD87346.1 - 1.6e-40 136.7 3.7 1e-13 50.8 0.3 3.1 3 0 0 3 3 3 3 Bacterial tandem repeat domain 1 Glyoxalase_4 PF13669.6 EGD87346.1 - 0.097 13.0 0.0 1.6 9.0 0.0 2.4 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HLH PF00010.26 EGD87348.1 - 9.3e-07 28.7 0.2 3.2e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain NST1 PF13945.6 EGD87348.1 - 0.38 10.9 20.5 0.2 11.7 4.2 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator BRF1 PF07741.13 EGD87348.1 - 2.3 8.6 7.2 9.2 6.7 1.0 2.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain TMEM135_C_rich PF15982.5 EGD87349.1 - 0.00018 22.1 1.7 0.00046 20.8 1.7 1.7 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Cation_ATPase_C PF00689.21 EGD87349.1 - 0.02 14.6 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Semialdhyde_dhC PF02774.18 EGD87350.2 - 3e-37 128.5 0.0 4.6e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EGD87350.2 - 6.5e-29 100.8 0.0 3.3e-28 98.6 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EGD87350.2 - 0.049 14.5 0.0 0.11 13.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 EGD87350.2 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Peptidase_M35 PF02102.15 EGD87351.2 - 4.7e-106 354.7 6.1 5.2e-106 354.6 6.1 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EGD87351.2 - 1.1e-42 146.0 0.6 2e-42 145.2 0.6 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EGD87351.2 - 8.8e-05 22.2 0.6 0.00062 19.4 0.6 2.0 1 1 0 1 1 1 1 Putative peptidase family Polysacc_deac_1 PF01522.21 EGD87354.2 - 9.9e-28 96.5 0.0 2.1e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGD87354.2 - 0.018 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 CtaG_Cox11 PF04442.14 EGD87355.1 - 8e-62 207.7 0.1 1.1e-61 207.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DNA_pol3_delta2 PF13177.6 EGD87356.1 - 1.1e-10 41.5 0.1 2.2e-10 40.5 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EGD87356.1 - 1.2e-06 29.0 0.1 2.3e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGD87356.1 - 4.3e-06 27.0 0.1 1.5e-05 25.3 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGD87356.1 - 0.00047 20.6 0.3 0.0036 17.7 0.2 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EGD87356.1 - 0.0011 18.8 0.3 0.0027 17.5 0.3 1.6 1 1 0 1 1 1 1 AAA domain Rep_fac_C PF08542.11 EGD87356.1 - 0.0076 16.6 0.1 0.022 15.1 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 EGD87356.1 - 0.012 15.6 0.0 0.051 13.5 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain ABC_tran PF00005.27 EGD87356.1 - 0.02 15.4 0.1 0.043 14.3 0.1 1.8 1 1 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 EGD87356.1 - 0.073 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer ResIII PF04851.15 EGD87356.1 - 0.088 12.8 0.3 0.36 10.8 0.3 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TK PF00265.18 EGD87356.1 - 0.15 11.9 0.7 0.77 9.6 0.7 1.9 1 1 0 1 1 1 0 Thymidine kinase Ribosomal_L16 PF00252.18 EGD87357.1 - 1.1e-30 106.3 0.1 1.4e-30 106.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 EGD87358.2 - 1.5e-23 83.7 0.5 1.2e-22 80.8 0.2 2.2 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EGD87358.2 - 1.6e-13 50.8 0.0 5.4e-13 49.1 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EGD87358.2 - 1.3e-09 38.6 1.9 1.9e-09 38.1 0.1 2.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGD87358.2 - 0.0001 22.3 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EGD87358.2 - 0.00037 20.8 0.0 0.001 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGD87358.2 - 0.0013 19.1 0.1 0.0057 17.1 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGD87358.2 - 0.0016 18.2 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EGD87358.2 - 0.0038 17.3 0.0 0.0098 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGD87358.2 - 0.004 17.3 0.2 0.012 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGD87358.2 - 0.0096 16.5 0.0 0.027 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGD87358.2 - 0.02 14.6 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 EGD87358.2 - 0.024 14.4 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGD87358.2 - 0.027 14.4 0.0 0.23 11.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGD87358.2 - 0.03 14.0 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGD87358.2 - 0.046 13.6 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain 5_3_exonuc PF01367.20 EGD87358.2 - 0.076 13.6 0.0 0.34 11.6 0.0 2.1 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold NTPase_1 PF03266.15 EGD87358.2 - 0.11 12.4 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 EGD87358.2 - 0.45 10.3 0.0 0.45 10.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 EGD87358.2 - 0.78 10.2 6.9 1.5 9.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain Hep_59 PF07052.11 EGD87358.2 - 3 8.6 11.5 0.28 12.0 3.7 2.4 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Amino_oxidase PF01593.24 EGD87359.1 - 1.7e-08 34.2 0.0 1.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HTH_Tnp_Mu_2 PF09039.11 EGD87359.1 - 0.085 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain Septin PF00735.18 EGD87360.2 - 1.1e-104 349.7 1.5 1.1e-104 349.7 1.5 1.8 2 0 0 2 2 2 1 Septin GTP_EFTU PF00009.27 EGD87360.2 - 0.016 14.8 3.7 0.97 8.9 0.0 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Exonuc_VII_L PF02601.15 EGD87360.2 - 0.037 13.6 7.4 0.059 12.9 7.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2937 PF11157.8 EGD87360.2 - 0.15 11.8 4.3 0.26 11.0 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) ATP_bind_1 PF03029.17 EGD87360.2 - 0.66 9.7 3.2 0.64 9.8 0.1 2.4 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Atg14 PF10186.9 EGD87360.2 - 1.1 8.3 8.8 1.6 7.7 8.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 EGD87360.2 - 3.9 6.0 9.6 6.3 5.3 9.6 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Strep_SA_rep PF06696.11 EGD87360.2 - 4 7.6 7.0 2 8.5 3.7 2.2 1 1 1 2 2 2 0 Streptococcal surface antigen repeat UPF0121 PF03661.13 EGD87361.2 - 8.8e-25 87.5 6.7 2e-18 66.7 2.1 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0121) CHCH PF06747.13 EGD87364.1 - 8.9e-07 28.9 5.3 1.5e-06 28.2 5.3 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EGD87364.1 - 0.0027 18.1 1.8 0.0058 17.0 1.8 1.7 1 0 0 1 1 1 1 GCK domain DUF2981 PF11200.8 EGD87364.1 - 2.2 7.9 5.8 0.29 10.8 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) TPK_B1_binding PF04265.14 EGD87365.2 - 5.7e-18 64.4 0.0 9.7e-18 63.7 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.16 EGD87365.2 - 1.3e-11 44.5 0.0 2.4e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain FMO-like PF00743.19 EGD87369.1 - 4.6e-18 64.9 0.1 4.1e-17 61.8 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGD87369.1 - 2.3e-12 46.8 0.0 1.5e-11 44.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGD87369.1 - 1.7e-09 37.8 0.0 3.9e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGD87369.1 - 1.9e-08 33.9 0.0 5.4e-06 25.9 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGD87369.1 - 1.6e-07 30.8 0.1 1.7e-05 24.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EGD87369.1 - 3.6e-05 23.5 0.0 0.00021 21.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EGD87369.1 - 0.00091 19.3 0.0 0.17 12.0 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EGD87369.1 - 0.011 15.0 0.2 0.019 14.2 0.2 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EGD87369.1 - 0.019 15.0 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EGD87369.1 - 0.024 13.7 0.3 0.034 13.2 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EGD87369.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase MrpF_PhaF PF04066.13 EGD87369.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) NAD_binding_7 PF13241.6 EGD87369.1 - 0.19 12.2 0.0 3.7 8.0 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 EGD87369.1 - 0.43 9.2 1.4 0.8 8.3 1.4 1.4 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_18 PF00704.28 EGD87370.1 - 3.9e-84 283.1 0.2 4.6e-84 282.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EGD87370.1 - 1.8e-12 47.1 0.1 3.5e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 LysM domain FAS_N PF17828.1 EGD87371.1 - 0.096 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Glyco_transf_8 PF01501.20 EGD87372.1 - 0.00015 21.5 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Fox-1_C PF12414.8 EGD87372.1 - 0.027 14.8 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal DUF2492 PF10678.9 EGD87372.1 - 0.068 13.5 0.0 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2492) Mannosyl_trans3 PF11051.8 EGD87372.1 - 0.13 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Mannosyltransferase putative SUN PF03856.13 EGD87376.1 - 2e-86 289.5 3.7 2.4e-86 289.2 3.7 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Ribosomal_L1 PF00687.21 EGD87377.1 - 9.6e-58 195.3 0.2 1.8e-57 194.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family ETF PF01012.21 EGD87378.1 - 5.2e-41 140.5 1.5 1.1e-40 139.5 1.5 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EGD87378.1 - 2.5e-33 114.0 0.1 5.8e-33 112.8 0.1 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Kdo PF06293.14 EGD87379.1 - 5.3e-07 29.2 0.1 1.1e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGD87379.1 - 6.2e-06 26.3 0.2 6.2e-06 26.3 0.2 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGD87379.1 - 1.3e-05 24.7 0.0 4.3e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EGD87379.1 - 0.029 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EGD87379.1 - 0.033 13.8 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Gla PF00594.20 EGD87379.1 - 1 9.6 6.3 0.17 12.1 0.5 2.3 2 0 0 2 2 2 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain AAA PF00004.29 EGD87381.2 - 5.7e-12 46.2 0.0 1.2e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGD87381.2 - 1e-05 25.3 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EGD87381.2 - 1.3e-05 25.3 0.1 5e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 EGD87381.2 - 1.5e-05 25.0 0.0 3.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGD87381.2 - 2.1e-05 24.8 0.0 5.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGD87381.2 - 0.00068 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGD87381.2 - 0.0025 18.0 0.0 0.0065 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGD87381.2 - 0.0031 17.8 0.5 0.1 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGD87381.2 - 0.0084 16.5 0.0 0.036 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 EGD87381.2 - 0.039 13.9 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 NTPase DUF1776 PF08643.10 EGD87381.2 - 0.04 13.3 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TsaE PF02367.17 EGD87381.2 - 0.065 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EGD87381.2 - 0.13 11.5 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin RsgA_GTPase PF03193.16 EGD87381.2 - 0.32 10.9 1.2 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_17 PF13207.6 EGD87381.2 - 0.62 10.5 0.0 0.62 10.5 0.0 2.2 2 0 0 2 2 1 0 AAA domain SWIRM-assoc_1 PF16495.5 EGD87383.2 - 1.9e-30 104.6 8.5 1.9e-30 104.6 8.5 1.9 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EGD87383.2 - 6.1e-10 39.1 0.1 1.2e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGD87383.2 - 2.6e-06 27.6 0.2 5.9e-06 26.4 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGD87383.2 - 0.083 13.1 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 ZZ PF00569.17 EGD87383.2 - 0.33 10.8 0.1 0.33 10.8 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type AAA_9 PF12781.7 EGD87383.2 - 1.3 8.1 4.9 0.37 9.9 1.0 1.9 2 0 0 2 2 2 0 ATP-binding dynein motor region Presenilin PF01080.17 EGD87383.2 - 2.8 6.6 3.7 3.6 6.2 3.7 1.1 1 0 0 1 1 1 0 Presenilin ERO1 PF04137.15 EGD87384.1 - 0.035 13.3 1.3 0.063 12.5 1.3 1.4 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) NOA36 PF06524.12 EGD87384.1 - 0.46 9.7 5.1 0.83 8.9 5.1 1.4 1 0 0 1 1 1 0 NOA36 protein Helicase_C PF00271.31 EGD87385.2 - 3.2e-13 50.0 0.0 7.2e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD87385.2 - 1.3e-06 28.6 0.0 3.2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGD87385.2 - 0.034 13.9 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF5643 PF18705.1 EGD87386.1 - 0.04 13.9 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5643) PGAP1 PF07819.13 EGD87389.2 - 9e-67 225.2 0.0 1.4e-66 224.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EGD87389.2 - 9.1e-05 23.2 0.0 0.00018 22.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EGD87389.2 - 0.00072 19.5 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EGD87389.2 - 0.00091 18.9 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGD87389.2 - 0.0021 17.8 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EGD87389.2 - 0.0041 16.4 0.0 0.0093 15.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 EGD87389.2 - 0.0045 16.2 0.0 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 EGD87389.2 - 0.016 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF915 PF06028.11 EGD87389.2 - 0.21 10.9 0.0 0.42 9.9 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_M28 PF04389.17 EGD87390.2 - 2.7e-11 43.5 0.1 1.1e-10 41.6 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGD87390.2 - 0.0025 17.6 0.0 0.0031 17.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 fn3 PF00041.21 EGD87390.2 - 0.045 14.1 0.1 0.081 13.3 0.1 1.4 1 0 0 1 1 1 0 Fibronectin type III domain APG17 PF04108.12 EGD87394.1 - 5.8e-128 427.4 0.2 6.8e-128 427.1 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF4795 PF16043.5 EGD87394.1 - 0.021 14.4 1.6 0.22 11.1 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Tweety PF04906.13 EGD87394.1 - 0.023 13.4 0.6 0.19 10.4 0.0 2.5 3 0 0 3 3 3 0 Tweety FRB_dom PF08771.11 EGD87394.1 - 0.034 14.5 0.1 0.41 11.1 0.0 2.7 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain Herpes_UL6 PF01763.16 EGD87394.1 - 0.14 10.6 1.2 0.4 9.1 0.3 1.9 2 0 0 2 2 2 0 Herpesvirus UL6 like DUF1542 PF07564.11 EGD87394.1 - 0.16 12.1 0.6 0.58 10.3 0.6 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) HD_2 PF12917.7 EGD87394.1 - 0.32 10.7 1.6 0.82 9.4 0.3 2.3 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme WD40 PF00400.32 EGD87395.1 - 1.7e-47 158.4 21.4 5.9e-09 36.4 0.6 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 EGD87395.1 - 3.4e-14 52.5 0.3 7e-14 51.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 EGD87395.1 - 1.6e-11 43.6 6.7 0.0049 15.6 0.1 5.7 5 1 1 6 6 6 4 Nucleoporin Nup120/160 F-box PF00646.33 EGD87395.1 - 1.5e-10 40.7 0.3 4e-10 39.3 0.1 1.8 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 EGD87395.1 - 4e-10 39.9 0.4 0.0014 18.9 0.0 4.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EGD87395.1 - 0.001 18.9 0.1 0.0036 17.2 0.0 1.9 2 0 0 2 2 2 1 F-box WD40_like PF17005.5 EGD87395.1 - 0.002 17.5 0.1 0.0033 16.8 0.1 1.3 1 0 0 1 1 1 1 WD40-like domain CBP_BcsO PF17037.5 EGD87399.2 - 0.1 12.7 2.2 0.13 12.4 2.2 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO Caskin-tail PF16632.5 EGD87400.1 - 0.14 12.6 4.2 0.37 11.2 0.1 2.7 2 0 0 2 2 2 0 C-terminal region of Caskin SMC_hinge PF06470.13 EGD87402.2 - 1.2e-32 112.7 0.3 3.2e-31 108.0 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 EGD87402.2 - 3.1e-27 95.4 13.5 4.9e-27 94.8 13.5 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGD87402.2 - 2.6e-12 47.2 0.2 2.6e-12 47.2 0.2 2.2 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGD87402.2 - 2.8e-07 30.6 4.2 2.8e-07 30.6 4.2 2.3 1 1 0 2 2 1 1 AAA ATPase domain APG6_N PF17675.1 EGD87402.2 - 0.00049 20.6 65.3 0.035 14.6 6.6 4.5 3 1 1 4 4 4 2 Apg6 coiled-coil region ATG16 PF08614.11 EGD87402.2 - 0.033 14.4 58.1 0.67 10.1 10.9 4.7 3 2 2 5 5 5 0 Autophagy protein 16 (ATG16) SbcCD_C PF13558.6 EGD87402.2 - 0.078 13.2 0.1 0.57 10.4 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit COG5 PF10392.9 EGD87402.2 - 2 8.6 25.2 0.076 13.2 5.6 4.6 4 1 0 4 4 4 0 Golgi transport complex subunit 5 BLOC1_2 PF10046.9 EGD87402.2 - 2.3 8.6 37.4 0.61 10.4 2.4 5.5 3 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 EGD87402.2 - 3.2 7.0 58.4 1.5 8.1 16.4 4.5 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding EspB_PE PF18625.1 EGD87402.2 - 3.7 8.1 8.7 0.55 10.7 0.3 3.4 2 2 1 3 3 3 0 ESX-1 secreted protein B PE domain DUF4407 PF14362.6 EGD87402.2 - 3.9 6.7 46.0 0.12 11.7 16.0 3.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 EGD87402.2 - 8.3 7.0 39.0 2.3 8.8 13.2 4.7 2 2 2 4 4 4 0 Protein of unknown function DUF16 DUF948 PF06103.11 EGD87402.2 - 8.9 6.7 17.3 1.5 9.1 3.9 4.5 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Sec34 PF04136.15 EGD87402.2 - 9.7 6.1 31.2 0.58 10.0 2.4 4.2 3 1 1 4 4 4 0 Sec34-like family DUF3605 PF12239.8 EGD87403.1 - 1.5e-60 203.9 0.0 1.8e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FAD_binding_6 PF00970.24 EGD87404.1 - 4.8e-32 110.2 0.0 8e-32 109.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGD87404.1 - 3.9e-28 98.3 0.0 6.2e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGD87404.1 - 1.8e-05 24.9 0.0 0.0018 18.4 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF4176 PF13780.6 EGD87404.1 - 0.016 15.2 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) FAD_binding_9 PF08021.11 EGD87404.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain WD40 PF00400.32 EGD87405.1 - 2.2e-09 37.8 26.0 0.00018 22.2 0.5 7.8 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD87405.1 - 0.00092 19.5 0.1 5.2 7.4 0.0 4.9 4 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD87405.1 - 0.032 12.9 0.1 0.091 11.4 0.1 1.8 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGD87405.1 - 0.067 12.1 0.2 0.54 9.2 0.0 2.2 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein tRNA-synt_1d PF00750.19 EGD87406.2 - 9.5e-96 320.8 8.1 5.1e-94 315.1 8.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EGD87406.2 - 1.2e-28 99.6 0.0 3e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EGD87406.2 - 2e-05 25.1 1.0 7.3e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DUF16 PF01519.16 EGD87406.2 - 0.025 15.0 3.5 0.24 11.9 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 RRN3 PF05327.11 EGD87409.1 - 0.26 9.8 6.1 0.43 9.1 6.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Plasmodium_Vir PF05795.11 EGD87409.1 - 2.3 7.5 6.3 7.3 5.9 6.3 1.9 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PPP4R2 PF09184.11 EGD87409.1 - 2.8 7.5 20.3 2.1 7.9 0.6 2.7 3 0 0 3 3 3 0 PPP4R2 Myc-LZ PF02344.15 EGD87411.1 - 0.043 13.9 5.1 0.7 10.0 1.3 2.9 2 0 0 2 2 2 0 Myc leucine zipper domain DUF3606 PF12244.8 EGD87411.1 - 0.1 12.6 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Tn7_Tnp_TnsA_C PF08721.11 EGD87411.1 - 0.13 12.9 0.8 5.4 7.7 0.1 2.7 2 0 0 2 2 2 0 TnsA endonuclease C terminal Dabb PF07876.12 EGD87413.1 - 6.3e-23 81.2 0.0 7.2e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ECD PF18432.1 EGD87413.1 - 0.09 12.7 0.0 0.16 11.9 0.0 1.4 1 1 1 2 2 2 0 Extracellular Cadherin domain DEAD PF00270.29 EGD87415.1 - 3.9e-40 137.5 1.6 8.1e-40 136.4 1.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD87415.1 - 1.1e-31 109.5 0.2 4.2e-30 104.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD87415.1 - 8e-08 32.5 0.0 2.4e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RIG-I_C PF18119.1 EGD87415.1 - 0.05 13.6 1.0 0.94 9.5 0.5 2.4 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain Flavi_DEAD PF07652.14 EGD87415.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.6 EGD87415.1 - 0.15 12.4 1.0 0.82 10.0 1.0 2.2 1 1 0 1 1 1 0 AAA domain Acyltransferase PF01553.21 EGD87417.1 - 8.3e-15 54.6 0.0 1.7e-14 53.6 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.9 EGD87418.1 - 1.1e-44 151.0 0.4 1.3e-44 150.8 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 bZIP_C PF12498.8 EGD87421.2 - 2.2 9.3 10.9 1 10.3 2.7 2.6 1 1 2 3 3 3 0 Basic leucine-zipper C terminal Annexin PF00191.20 EGD87422.1 - 1.6e-61 204.2 0.0 2.2e-17 62.8 0.0 4.1 4 0 0 4 4 4 4 Annexin DUF5617 PF18493.1 EGD87422.1 - 0.0002 21.4 2.8 0.16 12.1 1.1 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF5617) OST-HTH PF12872.7 EGD87422.1 - 0.089 12.6 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 OST-HTH/LOTUS domain EBP PF05241.12 EGD87423.1 - 2.5e-62 209.5 4.7 3.1e-62 209.2 4.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein zf-RING_UBOX PF13445.6 EGD87425.1 - 3.1e-08 33.5 6.2 3.1e-08 33.5 6.2 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGD87425.1 - 1e-07 31.7 6.1 1e-07 31.7 6.1 4.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGD87425.1 - 3.4e-07 30.0 2.5 3.4e-07 30.0 2.5 4.4 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGD87425.1 - 1.1e-05 25.6 7.5 1.1e-05 25.6 7.5 4.4 4 0 0 4 4 4 1 Ring finger domain zf-RING_6 PF14835.6 EGD87425.1 - 1.6e-05 24.6 0.7 1.6e-05 24.6 0.7 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EGD87425.1 - 0.00033 20.7 7.6 0.00033 20.7 7.6 3.7 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING SH3_9 PF14604.6 EGD87425.1 - 0.0015 18.4 0.1 0.0015 18.4 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EGD87425.1 - 0.16 11.6 0.2 0.38 10.4 0.2 1.6 1 0 0 1 1 1 0 SH3 domain Spt20 PF12090.8 EGD87425.1 - 1 8.9 9.8 2.5 7.7 9.8 1.6 1 0 0 1 1 1 0 Spt20 family TERB2 PF15101.6 EGD87425.1 - 1.1 9.3 3.4 2.9 7.9 3.4 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF5349 PF17298.2 EGD87426.1 - 0.036 13.8 0.8 0.042 13.6 0.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5349) SSP160 PF06933.11 EGD87426.1 - 7.1 4.7 11.6 8.6 4.4 11.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CENP-T_C PF15511.6 EGD87428.1 - 6.1e-09 36.0 0.1 7.4e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EGD87428.1 - 1.9e-05 25.0 0.2 2.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EGD87428.1 - 7e-05 22.9 0.1 0.0001 22.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGD87428.1 - 0.00017 21.8 0.1 0.00036 20.8 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EGD87428.1 - 0.00021 21.6 0.1 0.00028 21.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EGD87428.1 - 0.0038 17.3 0.0 0.0045 17.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGD87428.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 EGD87428.1 - 0.052 14.0 0.1 0.098 13.2 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 EGD87428.1 - 0.1 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Peptidase_M28 PF04389.17 EGD87430.2 - 1.6e-22 80.2 0.0 1.8e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGD87430.2 - 0.0074 16.0 0.2 0.0094 15.7 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Mito_carr PF00153.27 EGD87431.2 - 1.7e-13 50.3 0.1 8.7e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein CRIM PF16978.5 EGD87433.1 - 2.9e-43 147.4 0.0 4.9e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EGD87433.1 - 2.1e-26 92.3 0.5 4e-26 91.4 0.5 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 EGD87433.1 - 0.01 16.0 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 0 TUG ubiquitin-like domain Pkinase PF00069.25 EGD87434.2 - 3.1e-60 203.8 0.0 3.6e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87434.2 - 1.8e-30 106.1 0.0 2.4e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD87434.2 - 6.8e-08 32.2 0.0 8.4e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGD87434.2 - 0.027 13.6 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EGD87434.2 - 0.033 14.1 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-Tim10_DDP PF02953.15 EGD87436.1 - 3.5e-22 77.8 3.7 5.1e-22 77.3 3.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3475 PF11961.8 EGD87436.1 - 0.024 14.7 0.4 0.23 11.6 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3475) Lectin_leg-like PF03388.13 EGD87437.1 - 3.6e-61 206.5 0.0 4.9e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EGD87437.1 - 7.9e-07 29.3 0.0 1.2e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EGD87437.1 - 0.00022 20.8 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain BRF1 PF07741.13 EGD87438.1 - 0.067 13.5 21.0 0.14 12.5 10.6 3.1 2 1 0 2 2 2 0 Brf1-like TBP-binding domain PRCC PF10253.9 EGD87439.1 - 2.7e-36 126.4 1.4 2.7e-36 126.4 1.4 3.7 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting YugN PF08868.10 EGD87439.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 YugN-like family T2SSC PF11356.8 EGD87439.1 - 0.36 10.7 2.0 0.83 9.5 0.1 2.5 1 1 2 3 3 3 0 Type II secretion system protein C HNH_2 PF13391.6 EGD87440.1 - 9.1e-14 51.4 0.1 2e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease ATP-grasp_3 PF02655.14 EGD87441.1 - 3.1e-08 33.8 0.0 4.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EGD87441.1 - 1.9e-06 27.6 0.0 3.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain AAA_5 PF07728.14 EGD87442.1 - 3.1e-133 438.6 0.0 1.9e-23 83.0 0.0 10.2 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EGD87442.1 - 2.7e-51 172.2 4.5 3.4e-20 72.2 0.0 6.0 5 0 0 5 5 5 4 Midasin AAA lid domain AAA_7 PF12775.7 EGD87442.1 - 8.4e-31 106.9 0.2 3.6e-05 23.3 0.0 7.1 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA PF00004.29 EGD87442.1 - 2.4e-30 105.7 0.0 0.00012 22.5 0.0 7.0 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 EGD87442.1 - 4.7e-30 103.8 0.1 2.1e-29 101.7 0.0 2.3 2 0 0 2 2 1 1 Midasin AAA lid domain AAA_3 PF07726.11 EGD87442.1 - 4.7e-30 104.1 0.0 3.2e-11 43.2 0.0 7.5 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGD87442.1 - 1.3e-28 100.5 11.7 0.00039 20.8 0.2 8.5 6 2 0 6 6 6 6 AAA ATPase domain Dynein_heavy PF03028.15 EGD87442.1 - 1.8e-19 70.0 0.3 2.4e-05 24.4 0.0 7.6 8 1 0 8 8 5 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 EGD87442.1 - 3e-19 69.4 0.0 0.02 14.6 0.0 6.6 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_22 PF13401.6 EGD87442.1 - 9.9e-19 68.0 2.9 0.076 13.3 0.0 8.8 7 1 0 7 7 7 4 AAA domain AAA_6 PF12774.7 EGD87442.1 - 1.4e-18 67.0 0.0 0.003 16.6 0.0 8.4 8 1 0 8 8 7 3 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 EGD87442.1 - 3.5e-16 59.3 0.5 0.1 12.6 0.0 6.8 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGD87442.1 - 5.6e-15 55.7 0.1 0.033 14.4 0.0 7.0 6 0 0 6 6 6 3 AAA domain AAA_30 PF13604.6 EGD87442.1 - 6.5e-15 55.3 0.1 0.05 13.3 0.0 7.8 6 2 0 6 6 6 2 AAA domain Mg_chelatase PF01078.21 EGD87442.1 - 8.5e-15 54.7 3.5 0.76 9.1 0.0 9.1 8 1 0 9 9 9 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGD87442.1 - 2e-14 54.3 5.0 0.43 11.1 0.0 7.5 7 0 0 7 7 6 3 AAA domain AAA_14 PF13173.6 EGD87442.1 - 5e-13 49.2 0.0 0.00092 19.3 0.0 7.5 8 0 0 8 8 6 1 AAA domain RuvB_N PF05496.12 EGD87442.1 - 1.5e-12 47.5 1.4 0.24 11.1 0.0 6.5 7 0 0 7 7 6 3 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EGD87442.1 - 1.9e-12 47.8 7.3 0.033 14.7 0.0 7.3 7 0 0 7 7 6 3 ABC transporter NACHT PF05729.12 EGD87442.1 - 4.8e-11 42.9 6.8 0.28 11.1 0.1 7.4 7 0 0 7 7 7 2 NACHT domain AAA_19 PF13245.6 EGD87442.1 - 7.4e-11 42.6 0.4 4.3 7.7 0.1 6.9 6 0 0 6 6 6 0 AAA domain Sigma54_activ_2 PF14532.6 EGD87442.1 - 9.8e-11 41.9 0.6 0.045 13.9 0.0 6.4 6 0 0 6 6 6 2 Sigma-54 interaction domain RNA_helicase PF00910.22 EGD87442.1 - 1.6e-10 41.3 0.4 4 7.9 0.0 6.7 6 0 0 6 6 6 0 RNA helicase Rad17 PF03215.15 EGD87442.1 - 4.2e-10 39.9 0.8 0.057 13.3 0.0 6.1 6 0 0 6 6 6 1 Rad17 P-loop domain IstB_IS21 PF01695.17 EGD87442.1 - 8.2e-09 35.4 0.0 2.4 7.9 0.0 6.3 6 0 0 6 6 6 1 IstB-like ATP binding protein AAA_28 PF13521.6 EGD87442.1 - 2.1e-08 34.6 2.2 0.53 10.5 0.0 6.0 6 0 0 6 6 6 2 AAA domain T2SSE PF00437.20 EGD87442.1 - 3.1e-08 33.0 0.5 0.051 12.6 0.0 5.1 5 0 0 5 5 5 1 Type II/IV secretion system protein AAA_29 PF13555.6 EGD87442.1 - 3.2e-08 33.2 0.3 3.7 7.4 0.0 6.5 6 0 0 6 6 6 0 P-loop containing region of AAA domain SRP54 PF00448.22 EGD87442.1 - 4.1e-08 33.1 2.4 2.7 7.5 0.0 5.8 6 0 0 6 6 6 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 EGD87442.1 - 4.2e-08 33.0 1.3 0.33 10.7 0.0 6.1 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 EGD87442.1 - 6.2e-08 32.1 8.7 1 8.5 0.2 6.4 7 0 0 7 7 6 2 Protein of unknown function (DUF815) AAA_24 PF13479.6 EGD87442.1 - 9.4e-08 32.0 0.1 1.3 8.7 0.0 6.4 7 0 0 7 7 6 1 AAA domain RsgA_GTPase PF03193.16 EGD87442.1 - 2e-07 31.0 5.2 1.3 8.9 0.3 5.9 6 0 0 6 6 5 1 RsgA GTPase Zeta_toxin PF06414.12 EGD87442.1 - 3.9e-07 29.5 10.3 0.028 13.7 0.0 7.1 8 0 0 8 8 7 1 Zeta toxin AAA_25 PF13481.6 EGD87442.1 - 7.2e-07 29.0 5.2 2.9 7.4 0.0 6.2 7 0 0 7 7 5 1 AAA domain TIP49 PF06068.13 EGD87442.1 - 9.1e-07 28.4 1.6 1.4 8.1 0.0 5.1 5 0 0 5 5 5 1 TIP49 P-loop domain TniB PF05621.11 EGD87442.1 - 1.3e-06 28.0 0.1 8.8 5.7 0.0 5.7 6 0 0 6 6 5 0 Bacterial TniB protein Roc PF08477.13 EGD87442.1 - 2.2e-06 27.9 3.5 11 6.2 0.0 6.3 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 EGD87442.1 - 3.6e-06 27.1 0.0 18 5.2 0.0 6.1 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea MCM PF00493.23 EGD87442.1 - 6.3e-06 25.4 0.0 4.8 6.2 0.0 4.9 5 0 0 5 5 5 0 MCM P-loop domain ResIII PF04851.15 EGD87442.1 - 3.7e-05 23.8 0.1 3.3 7.7 0.0 5.4 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 EGD87442.1 - 0.00014 21.8 0.0 5.8 6.7 0.0 4.6 5 0 0 5 5 4 0 Bacterial dnaA protein AAA_17 PF13207.6 EGD87442.1 - 0.0012 19.2 1.2 14 6.1 0.0 4.7 4 0 0 4 4 4 0 AAA domain DnaB_C PF03796.15 EGD87442.1 - 0.0015 17.9 1.0 1.7 7.9 0.0 4.4 4 0 0 4 4 4 1 DnaB-like helicase C terminal domain CPT PF07931.12 EGD87442.1 - 0.0018 18.2 2.4 1.5 8.7 0.0 5.2 6 1 0 6 6 4 1 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 EGD87442.1 - 0.0023 17.3 0.1 15 4.9 0.0 4.6 4 0 0 4 4 4 0 KaiC Viral_helicase1 PF01443.18 EGD87442.1 - 0.0038 17.0 0.1 13 5.4 0.0 5.0 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 EGD87442.1 - 0.0057 16.6 9.0 2.2 8.1 0.0 5.8 8 0 0 8 8 4 1 NTPase ATP_bind_1 PF03029.17 EGD87442.1 - 0.01 15.7 6.7 8.8 6.0 0.1 5.4 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein PhoH PF02562.16 EGD87442.1 - 0.013 15.0 0.4 21 4.5 0.0 4.9 6 0 0 6 6 6 0 PhoH-like protein GAF_2 PF13185.6 EGD87442.1 - 0.017 15.4 0.0 0.062 13.6 0.0 2.0 1 0 0 1 1 1 0 GAF domain AAA_8 PF12780.7 EGD87442.1 - 0.036 13.4 8.2 33 3.7 0.0 6.8 8 0 0 8 8 7 0 P-loop containing dynein motor region D4 MMR_HSR1 PF01926.23 EGD87442.1 - 0.045 13.8 4.0 57 3.8 0.0 5.8 6 0 0 6 6 6 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 EGD87442.1 - 0.12 12.2 0.1 64 3.4 0.0 3.7 4 0 0 4 4 3 0 P-loop Nucleotide Kinase3 CbiA PF01656.23 EGD87442.1 - 0.13 12.3 0.4 8.2 6.5 0.0 3.8 4 0 0 4 4 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain dNK PF01712.19 EGD87442.1 - 0.17 11.7 2.8 7.2 6.4 0.0 3.8 4 0 0 4 4 3 0 Deoxynucleoside kinase KTI12 PF08433.10 EGD87442.1 - 0.47 9.8 6.0 20 4.5 0.2 4.8 5 0 0 5 5 5 0 Chromatin associated protein KTI12 cobW PF02492.19 EGD87442.1 - 0.61 9.7 8.0 27 4.3 0.0 4.8 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 EGD87442.1 - 1.4 8.5 3.3 71 3.0 0.0 4.3 5 0 0 5 5 5 0 Ras family Voltage_CLC PF00654.20 EGD87443.2 - 5.2e-91 305.5 24.2 5.2e-91 305.5 24.2 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGD87443.2 - 3.4e-05 24.2 0.1 0.22 12.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain P5CR_dimer PF14748.6 EGD87444.1 - 1.8e-31 108.4 3.3 2.9e-31 107.8 3.3 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EGD87444.1 - 1.8e-10 41.3 0.0 7e-08 33.0 0.0 2.9 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent CTK3 PF12243.8 EGD87445.1 - 4.8e-49 165.5 0.1 6.7e-49 165.0 0.1 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EGD87445.1 - 1.1e-20 73.5 12.7 1.3e-20 73.3 11.2 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus DUF4240 PF14024.6 EGD87445.1 - 0.031 14.5 0.5 0.95 9.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) CARD PF00619.21 EGD87445.1 - 0.061 13.3 0.2 0.25 11.4 0.0 2.1 2 1 0 3 3 3 0 Caspase recruitment domain U3_snoRNA_assoc PF08297.11 EGD87446.1 - 1.4e-10 41.7 0.0 1.4e-10 41.7 0.0 4.6 3 1 0 3 3 3 1 U3 snoRNA associated Nop53 PF07767.11 EGD87446.1 - 0.0046 16.4 23.1 0.0046 16.4 23.1 2.0 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) Borrelia_P83 PF05262.11 EGD87446.1 - 0.086 11.3 17.5 0.15 10.6 17.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2220 PF09983.9 EGD87446.1 - 0.16 11.3 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) V_ATPase_I PF01496.19 EGD87446.1 - 3.4 5.5 7.1 5.5 4.8 7.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF445 PF04286.12 EGD87447.1 - 0.23 11.2 7.8 0.4 10.4 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AAA_11 PF13086.6 EGD87447.1 - 0.58 9.9 6.6 1 9.1 6.6 1.4 1 0 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.24 EGD87447.1 - 0.77 9.7 2.8 5 7.0 0.0 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD OmpH PF03938.14 EGD87447.1 - 1.4 9.2 13.3 4.8 7.5 13.4 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Bacteriocin_IIc PF10439.9 EGD87447.1 - 9.8 6.4 7.9 20 5.4 7.9 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF155 PF02582.14 EGD87450.1 - 1.6e-51 174.9 0.2 2.3e-51 174.4 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Trypsin_2 PF13365.6 EGD87452.1 - 8.6e-06 26.7 0.3 6.1e-05 24.0 0.2 2.4 2 1 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.11 EGD87452.1 - 0.0013 17.3 0.0 0.012 14.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase family S64 Peptidase_S32 PF05579.13 EGD87452.1 - 0.029 13.6 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S7 PF00949.21 EGD87452.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_M78 PF06114.13 EGD87452.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 IrrE N-terminal-like domain HlyC PF02794.16 EGD87452.1 - 0.2 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 RTX toxin acyltransferase family p450 PF00067.22 EGD87454.1 - 2.2e-61 208.1 0.0 2.4e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ca_chan_IQ PF08763.11 EGD87454.1 - 0.0026 17.9 0.1 0.014 15.6 0.1 2.0 2 0 0 2 2 2 1 Voltage gated calcium channel IQ domain p450 PF00067.22 EGD87455.1 - 4.4e-55 187.3 0.0 5.6e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EGD87457.1 - 1.6e-27 96.2 0.0 1.4e-25 89.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD87457.1 - 2.3e-15 56.8 0.0 3.6e-14 52.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD87457.1 - 1.9e-05 24.7 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGD87457.1 - 0.0044 16.5 0.0 0.0076 15.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Csm1_B PF18211.1 EGD87457.1 - 0.01 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Csm1 subunit domain B Shikimate_DH PF01488.20 EGD87457.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 EGD87457.1 - 0.046 13.0 0.0 6.6 6.0 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1776 PF08643.10 EGD87457.1 - 0.081 12.3 0.0 0.38 10.1 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 EGD87457.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Plasmodium_Vir PF05795.11 EGD87459.1 - 0.053 13.0 0.1 0.076 12.4 0.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ADIP PF11559.8 EGD87459.1 - 0.16 12.1 0.8 0.27 11.3 0.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ApoL PF05461.11 EGD87459.1 - 0.23 10.7 0.3 0.39 10.0 0.3 1.2 1 0 0 1 1 1 0 Apolipoprotein L Hat1_N PF10394.9 EGD87460.1 - 6.6e-55 185.7 0.0 1.4e-54 184.6 0.0 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus DUF917 PF06032.12 EGD87461.2 - 2.1e-123 411.6 0.2 9e-122 406.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EGD87461.2 - 1.8e-25 89.8 6.9 2.6e-23 82.7 3.8 2.4 1 1 1 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGD87461.2 - 2.7e-08 33.8 2.8 1.5e-05 24.7 0.0 3.6 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region DUF3663 PF12404.8 EGD87461.2 - 0.016 15.3 0.0 0.051 13.6 0.0 1.9 1 0 0 1 1 1 0 Peptidase StbA PF06406.11 EGD87461.2 - 0.097 11.9 1.5 2.6 7.2 0.1 2.3 1 1 0 2 2 2 0 StbA protein Zip PF02535.22 EGD87464.2 - 4.7e-36 124.7 13.1 4.2e-29 101.8 4.1 3.1 2 1 0 3 3 3 3 ZIP Zinc transporter WD40 PF00400.32 EGD87465.1 - 1e-36 124.3 21.6 1.1e-06 29.2 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 EGD87465.1 - 1.8e-10 40.5 0.6 3.4e-10 39.6 0.6 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EGD87465.1 - 2e-10 40.8 0.9 0.14 12.5 0.0 6.2 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD87465.1 - 6.3e-07 28.4 4.6 0.068 11.8 0.1 5.3 2 2 3 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EGD87465.1 - 4.9e-06 26.1 0.0 0.0022 17.4 0.0 3.2 1 1 2 4 4 4 1 WD40-like domain F-box PF00646.33 EGD87465.1 - 0.00069 19.4 0.6 0.0016 18.2 0.6 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 EGD87465.1 - 0.007 16.0 1.2 0.026 14.1 0.5 2.2 1 1 1 2 2 2 1 PQQ-like domain F-box_5 PF18511.1 EGD87465.1 - 0.053 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 F-box Sugar_tr PF00083.24 EGD87468.2 - 1.4e-87 294.5 22.7 1.7e-87 294.1 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGD87468.2 - 7.9e-11 41.5 47.9 1.4e-06 27.5 15.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Propeptide_C25 PF08126.11 EGD87468.2 - 0.19 10.8 0.0 0.41 9.7 0.0 1.5 2 0 0 2 2 2 0 Propeptide_C25 DUF1641 PF07849.11 EGD87472.2 - 0.0078 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1641) RINGv PF12906.7 EGD87473.1 - 1.8e-09 37.6 2.2 1.5e-08 34.6 0.6 2.4 2 0 0 2 2 2 1 RING-variant domain GDNF PF02351.16 EGD87473.1 - 0.11 13.5 0.1 0.19 12.7 0.1 1.3 1 0 0 1 1 1 0 GDNF/GAS1 domain PHD_4 PF16866.5 EGD87473.1 - 0.12 12.5 1.9 0.82 9.8 0.6 2.5 2 0 0 2 2 2 0 PHD-finger DUF1218 PF06749.12 EGD87473.1 - 0.29 11.7 0.3 0.29 11.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) zf-RING_2 PF13639.6 EGD87473.1 - 0.37 11.2 3.6 5.5 7.4 0.8 2.3 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.29 EGD87473.1 - 1.7 8.6 6.2 0.5 10.3 2.8 1.9 2 0 0 2 2 2 0 PHD-finger DUF202 PF02656.15 EGD87473.1 - 8.1 7.0 8.6 88 3.7 8.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Proteasome PF00227.26 EGD87474.1 - 7.7e-58 195.1 0.0 6.2e-33 113.9 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EGD87474.1 - 9.3e-11 41.2 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-C2H2_jaz PF12171.8 EGD87477.1 - 0.0028 17.9 0.8 0.036 14.4 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 EGD87477.1 - 0.017 15.0 1.2 2.3 8.2 0.1 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.6 EGD87477.1 - 0.2 12.1 6.6 0.38 11.3 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGD87477.1 - 0.32 12.0 5.9 13 6.9 0.0 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGD87477.1 - 0.83 10.2 0.0 0.83 10.2 0.0 3.6 4 1 0 4 4 4 0 Zinc finger, C2H2 type 6PGD PF00393.19 EGD87478.2 - 1.3e-76 257.7 0.0 1.9e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGD87478.2 - 7.7e-31 107.4 0.1 1.4e-30 106.6 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EGD87478.2 - 5.3e-06 26.4 0.0 9.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EGD87478.2 - 0.0012 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 EGD87478.2 - 0.0092 16.0 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EGD87478.2 - 0.015 15.8 0.0 0.046 14.3 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 EGD87478.2 - 0.016 14.8 0.2 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EGD87478.2 - 0.081 12.3 0.5 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RTA1 PF04479.13 EGD87479.1 - 1.6e-71 240.2 6.4 2.1e-71 239.8 6.4 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3098 PF11297.8 EGD87479.1 - 0.074 12.7 3.4 1.5 8.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) EB PF01683.18 EGD87481.2 - 0.00061 20.0 4.2 0.00067 19.9 4.2 1.1 1 0 0 1 1 1 1 EB module LSM PF01423.22 EGD87482.2 - 1.6e-09 37.3 0.2 0.0009 18.9 0.1 2.4 2 0 0 2 2 2 2 LSM domain DUF334 PF03904.13 EGD87482.2 - 0.19 11.2 0.0 0.5 9.9 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF334) NUC173 PF08161.12 EGD87483.1 - 1.7e-78 263.0 1.0 4.3e-76 255.1 0.2 3.2 3 0 0 3 3 3 2 NUC173 domain HEAT_2 PF13646.6 EGD87483.1 - 0.046 14.1 0.6 4.7 7.7 0.3 3.8 2 1 0 2 2 2 0 HEAT repeats SYF2 PF08231.12 EGD87483.1 - 0.25 11.8 7.6 0.52 10.7 7.6 1.5 1 0 0 1 1 1 0 SYF2 splicing factor RsbRD_N PF14361.6 EGD87483.1 - 0.27 12.0 2.8 1.9 9.2 0.0 4.0 5 0 0 5 5 5 0 RsbT co-antagonist protein rsbRD N-terminal domain EFTUD2 PF16004.5 EGD87483.1 - 0.33 11.5 6.5 1 10.0 6.5 1.8 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus CPSF100_C PF13299.6 EGD87483.1 - 0.61 10.3 5.7 0.65 10.2 2.4 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 EGD87484.1 - 0.077 12.2 2.4 0.96 8.6 0.2 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Orf78 PF06024.12 EGD87484.1 - 0.08 13.2 0.0 0.56 10.5 0.0 2.4 3 0 0 3 3 3 0 Orf78 (ac78) NOA36 PF06524.12 EGD87484.1 - 0.71 9.1 16.9 1.6 8.0 16.9 1.6 1 0 0 1 1 1 0 NOA36 protein Presenilin PF01080.17 EGD87484.1 - 0.75 8.5 5.6 0.65 8.7 0.1 2.1 2 0 0 2 2 2 0 Presenilin Spem1 PF15670.5 EGD87484.1 - 1 8.9 12.1 1.6 8.3 1.5 2.2 2 0 0 2 2 2 0 Spermatid maturation protein 1 Afi1 PF07792.12 EGD87484.1 - 1.5 9.3 9.2 4 7.9 6.8 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Adeno_E3B PF03376.14 EGD87484.1 - 3.1 8.1 4.8 1.1 9.5 1.3 2.0 2 0 0 2 2 2 0 Adenovirus E3B protein TRAP_alpha PF03896.16 EGD87484.1 - 3.6 6.7 6.3 8.4 5.5 6.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RPN2_C PF18004.1 EGD87484.1 - 8.8 6.2 6.4 0.94 9.4 1.6 1.8 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain TPR_1 PF00515.28 EGD87486.1 - 2e-49 163.5 31.1 7.8e-08 31.8 0.1 11.3 10 2 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 EGD87486.1 - 5.7e-45 147.8 22.5 9.1e-06 25.4 0.0 11.2 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 EGD87486.1 - 1.2e-36 121.8 18.8 6.9e-07 29.0 0.0 10.8 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 EGD87486.1 - 1.9e-21 74.8 31.7 0.00014 22.0 0.2 10.3 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGD87486.1 - 2.7e-20 72.7 32.1 1.8e-05 25.2 0.0 7.1 7 1 0 8 8 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGD87486.1 - 3.4e-20 71.5 26.5 6e-05 22.6 1.5 9.0 5 2 4 9 9 9 6 TPR repeat TPR_19 PF14559.6 EGD87486.1 - 5.4e-18 65.3 34.7 2.5e-05 24.7 0.5 7.6 6 2 2 8 8 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 EGD87486.1 - 6.3e-17 61.0 32.1 0.0038 17.8 0.0 10.8 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGD87486.1 - 2.7e-16 58.9 38.4 7e-05 23.3 0.1 10.9 5 2 8 13 13 11 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGD87486.1 - 3e-15 55.0 19.1 0.041 13.9 0.1 9.3 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 EGD87486.1 - 5.5e-15 55.3 14.1 0.0013 18.9 0.3 7.1 2 2 6 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 EGD87486.1 - 1.6e-13 50.7 43.3 0.0002 21.6 0.8 8.6 5 2 4 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGD87486.1 - 7.6e-10 38.9 7.5 7.5e-08 32.5 2.0 3.8 3 1 1 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EGD87486.1 - 1.2e-05 24.7 26.0 0.036 13.3 0.1 6.2 2 1 3 6 6 6 3 Tetratricopeptide repeat DUF2225 PF09986.9 EGD87486.1 - 0.0017 18.1 4.5 0.93 9.2 0.0 2.9 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.10 EGD87486.1 - 0.33 9.9 2.3 3.1 6.7 0.4 2.7 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 EGD87486.1 - 0.82 9.6 16.9 21 5.2 0.2 7.0 6 1 1 7 7 7 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 EGD87488.1 - 0.001 19.4 21.0 0.0014 19.0 21.0 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain RXT2_N PF08595.11 EGD87488.1 - 0.013 15.5 9.5 0.014 15.4 9.5 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 EGD87488.1 - 0.019 14.3 18.4 0.021 14.2 18.4 1.0 1 0 0 1 1 1 0 NOA36 protein DUF2796 PF10986.8 EGD87488.1 - 0.055 13.4 5.1 0.062 13.3 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Cwf_Cwc_15 PF04889.12 EGD87488.1 - 0.058 13.1 17.5 0.063 13.0 17.5 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.14 EGD87488.1 - 0.092 12.5 9.0 0.1 12.4 9.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4820 PF16091.5 EGD87488.1 - 0.21 10.9 5.5 0.22 10.9 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PPP4R2 PF09184.11 EGD87488.1 - 0.22 11.1 13.3 0.22 11.1 13.3 1.0 1 0 0 1 1 1 0 PPP4R2 FAM176 PF14851.6 EGD87488.1 - 0.31 10.7 10.5 0.37 10.4 10.5 1.3 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 EGD87488.1 - 0.41 8.7 18.6 0.37 8.8 18.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Radial_spoke PF04712.12 EGD87488.1 - 0.49 9.3 7.0 0.44 9.4 7.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Nop14 PF04147.12 EGD87488.1 - 0.49 8.5 16.0 0.53 8.4 16.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2722 PF10846.8 EGD87488.1 - 0.61 9.0 8.5 0.7 8.8 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BUD22 PF09073.10 EGD87488.1 - 0.62 9.3 11.7 0.63 9.3 11.7 1.1 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 EGD87488.1 - 0.72 8.9 20.8 0.79 8.8 20.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.16 EGD87488.1 - 0.86 8.8 7.7 0.8 8.8 7.7 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ANAPC15 PF15243.6 EGD87488.1 - 0.94 9.9 17.8 1.1 9.6 17.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Afi1 PF07792.12 EGD87488.1 - 1.2 9.6 9.6 1.3 9.5 9.6 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Sigma70_ner PF04546.13 EGD87488.1 - 2.3 8.1 13.6 2.4 8.0 13.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Roughex PF06020.11 EGD87488.1 - 2.9 6.9 12.2 3.2 6.8 12.2 1.0 1 0 0 1 1 1 0 Drosophila roughex protein SDA1 PF05285.12 EGD87488.1 - 3 7.2 18.8 3.4 7.0 18.8 1.0 1 0 0 1 1 1 0 SDA1 Nucleo_P87 PF07267.11 EGD87488.1 - 3.2 6.5 10.7 3.6 6.3 10.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFB6 PF17110.5 EGD87488.1 - 3.5 7.3 8.5 3.8 7.2 8.5 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RNA_pol_3_Rpc31 PF11705.8 EGD87488.1 - 4.4 7.5 19.0 4.8 7.4 19.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sporozoite_P67 PF05642.11 EGD87488.1 - 4.8 5.1 11.5 5 5.1 11.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NPR3 PF03666.13 EGD87488.1 - 5.2 5.7 6.8 6 5.5 6.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Astro_capsid_p PF12226.8 EGD87488.1 - 5.7 6.0 15.2 6.2 5.9 15.2 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 EGD87488.1 - 7 4.8 16.6 7.4 4.7 16.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L3 PF00297.22 EGD87489.2 - 1.9e-179 596.4 10.5 2.4e-179 596.1 10.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 NuiA PF07924.11 EGD87490.1 - 0.0073 16.7 0.0 0.044 14.2 0.0 2.0 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein SKN1 PF03935.15 EGD87491.2 - 1.6e-218 726.2 0.1 2.2e-218 725.7 0.1 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) BCDHK_Adom3 PF10436.9 EGD87494.1 - 1.4e-72 242.8 0.0 2e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGD87494.1 - 6.3e-13 49.2 0.0 3.1e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGD87494.1 - 0.018 14.9 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4690 PF15756.5 EGD87495.2 - 0.023 15.3 3.0 0.037 14.6 0.0 2.6 2 1 1 3 3 3 0 Small Novel Rich in Cartilage Ank_2 PF12796.7 EGD87496.1 - 2.3e-27 95.4 0.4 4.4e-09 36.8 0.1 4.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGD87496.1 - 1e-20 73.5 1.2 4e-06 27.0 0.0 6.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGD87496.1 - 3.2e-18 65.8 3.3 3.2e-08 34.0 0.2 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD87496.1 - 5.2e-17 60.2 2.7 0.0018 18.6 0.0 7.1 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 EGD87496.1 - 7e-17 61.0 4.7 0.0011 19.3 0.1 6.6 6 0 0 6 6 6 4 Ankyrin repeat AAA_22 PF13401.6 EGD87496.1 - 1.8e-07 31.5 0.1 4.2e-06 27.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGD87496.1 - 5.9e-07 29.6 0.1 2.9e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EGD87496.1 - 0.0063 16.9 1.2 0.016 15.6 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain Helo_like_N PF17111.5 EGD87496.1 - 0.027 13.8 0.3 0.078 12.3 0.0 1.9 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Exo70 PF03081.15 EGD87497.1 - 4.8e-87 292.5 0.0 7.5e-87 291.8 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Laminin_II PF06009.12 EGD87497.1 - 0.29 11.2 2.3 2.6 8.0 0.3 2.7 2 0 0 2 2 2 0 Laminin Domain II Sec34 PF04136.15 EGD87497.1 - 0.42 10.5 2.1 4.6 7.1 0.0 3.4 3 2 1 4 4 4 0 Sec34-like family PLA2_B PF01735.18 EGD87498.1 - 3.5e-27 95.0 0.0 5.1e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PPR_2 PF13041.6 EGD87499.2 - 2.9e-10 40.2 0.0 0.021 15.0 0.1 5.6 3 2 3 6 6 6 3 PPR repeat family PPR_long PF17177.4 EGD87499.2 - 1.8e-08 34.0 0.0 0.00088 18.7 0.0 2.9 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EGD87499.2 - 9.8e-08 31.8 3.7 0.43 10.9 0.0 6.3 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 EGD87499.2 - 7e-07 29.2 0.1 0.16 12.0 0.0 4.4 3 1 1 4 4 4 2 Pentatricopeptide repeat domain Frtz PF11768.8 EGD87499.2 - 0.03 12.6 0.0 0.042 12.2 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Mic1 PF07035.12 EGD87499.2 - 0.11 12.2 0.4 9.1 6.0 0.0 3.2 3 1 1 4 4 4 0 Colon cancer-associated protein Mic1-like LSM PF01423.22 EGD87501.2 - 5.7e-18 64.4 0.0 7.3e-18 64.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGD87501.2 - 0.0048 17.0 0.0 0.0078 16.3 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain His_Phos_1 PF00300.22 EGD87502.2 - 1.7e-30 106.2 0.0 2.9e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) F-box-like PF12937.7 EGD87504.1 - 0.0013 18.6 0.1 0.0029 17.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EGD87504.1 - 0.05 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 F-box F-box PF00646.33 EGD87504.1 - 0.067 13.1 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 F-box domain MFS_1 PF07690.16 EGD87505.1 - 1.1e-37 129.8 74.6 2.7e-28 98.9 41.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD87505.1 - 8.2e-09 34.8 26.7 0.00012 21.2 9.3 2.9 1 1 1 2 2 2 2 Sugar (and other) transporter HNH_2 PF13391.6 EGD87506.2 - 1.3e-12 47.7 0.0 2.4e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_18 PF00704.28 EGD87507.2 - 6.7e-42 144.3 1.1 1e-41 143.7 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EGD87507.2 - 8.3e-09 35.4 0.0 2.8e-06 27.3 0.1 2.5 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 EGD87507.2 - 3.7e-05 24.1 8.5 3.7e-05 24.1 8.5 3.8 5 0 0 5 5 5 1 Chitin recognition protein HNH_2 PF13391.6 EGD87510.1 - 5.9e-09 35.9 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease CoA_binding_3 PF13727.6 EGD87512.1 - 0.027 14.5 3.0 0.043 13.8 0.6 2.5 3 0 0 3 3 3 0 CoA-binding domain Ldh_1_C PF02866.18 EGD87513.1 - 1.5e-47 161.7 0.0 3.2e-47 160.5 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGD87513.1 - 1.5e-43 148.3 0.0 2.2e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EGD87513.1 - 0.00012 21.1 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 EGD87513.1 - 0.12 12.0 0.2 0.51 9.9 0.2 2.0 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase AAA PF00004.29 EGD87514.1 - 1.5e-16 61.0 0.7 5.3e-16 59.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGD87514.1 - 0.00026 21.0 0.0 0.00079 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGD87514.1 - 0.0012 19.3 0.6 0.0056 17.1 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGD87514.1 - 0.0068 16.7 3.6 0.014 15.7 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.6 EGD87514.1 - 0.0099 15.6 0.0 0.029 14.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGD87514.1 - 0.027 14.8 0.1 0.094 13.0 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGD87514.1 - 0.042 13.6 0.0 0.042 13.6 0.0 4.6 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 EGD87514.1 - 0.1 12.8 0.1 0.1 12.8 0.1 3.3 3 2 0 3 3 3 0 AAA domain Peptidase_S64 PF08192.11 EGD87514.1 - 7 5.0 30.6 12 4.2 30.6 1.6 1 0 0 1 1 1 0 Peptidase family S64 Myb_DNA-bind_6 PF13921.6 EGD87517.1 - 0.00019 21.6 0.3 0.14 12.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EGD87517.1 - 0.0077 17.2 0.2 3.6 8.6 0.0 2.3 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Peptidase_S64 PF08192.11 EGD87518.2 - 0.23 9.9 0.0 0.32 9.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 HbrB PF08539.11 EGD87521.1 - 2.1e-50 171.0 0.2 7.3e-50 169.3 0.0 2.1 2 0 0 2 2 2 1 HbrB-like Ank_2 PF12796.7 EGD87522.1 - 5.8e-76 251.1 0.8 1.2e-16 61.1 0.3 6.4 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD87522.1 - 1.2e-61 204.3 4.4 3.7e-12 46.5 0.0 8.7 6 2 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD87522.1 - 8.7e-53 170.1 3.3 0.0009 19.5 0.0 13.5 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 EGD87522.1 - 1.3e-50 168.8 5.1 1.6e-07 31.4 0.1 12.1 2 1 11 13 13 13 12 Ankyrin repeats (many copies) Ank PF00023.30 EGD87522.1 - 2.7e-47 157.2 9.5 0.00011 22.5 0.0 12.7 13 0 0 13 13 13 9 Ankyrin repeat VWA_3_C PF18571.1 EGD87522.1 - 7.2 6.6 5.5 5 7.1 0.3 3.3 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain HNH_2 PF13391.6 EGD87523.1 - 7.5e-15 54.8 0.0 1.7e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 HNH endonuclease Gon7 PF08738.10 EGD87524.1 - 2.1e-13 50.3 1.7 6.8e-13 48.6 1.7 1.6 1 1 0 1 1 1 1 Gon7 family CNH PF00780.22 EGD87525.2 - 2.1e-16 60.4 0.0 8.3e-16 58.4 0.0 1.9 1 1 0 1 1 1 1 CNH domain 6PF2K PF01591.18 EGD87526.2 - 1.8e-81 272.7 0.0 2.3e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGD87526.2 - 4.2e-41 140.8 0.0 7.8e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGD87526.2 - 3.9e-06 27.1 0.0 7.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain APH PF01636.23 EGD87529.2 - 1e-17 64.8 0.0 1.4e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD87529.2 - 7.1e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EGD87529.2 - 0.0018 17.5 0.0 0.0051 16.0 0.0 1.6 2 0 0 2 2 2 1 Fructosamine kinase Pkinase PF00069.25 EGD87530.1 - 3.6e-22 79.0 0.0 4.5e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87530.1 - 4.3e-20 72.1 0.0 7.8e-20 71.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGD87530.1 - 0.00094 18.6 0.1 0.0043 16.4 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGD87530.1 - 0.0026 17.1 0.0 0.011 15.1 0.0 1.9 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGD87530.1 - 0.0065 16.1 0.0 0.0087 15.7 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGD87530.1 - 0.025 14.5 0.2 0.41 10.5 0.4 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family PIP49_C PF12260.8 EGD87530.1 - 0.043 13.4 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF5353 PF17304.2 EGD87531.2 - 3.4e-35 119.6 2.1 5.1e-35 119.0 2.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Rotamase PF00639.21 EGD87531.2 - 0.00033 21.6 1.0 0.00045 21.1 1.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Ax_dynein_light PF10211.9 EGD87531.2 - 0.029 14.3 4.5 0.042 13.8 4.5 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain OmpH PF03938.14 EGD87531.2 - 0.082 13.3 7.2 0.12 12.7 7.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF883 PF05957.13 EGD87531.2 - 0.16 12.6 4.0 0.29 11.7 4.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EGD87531.2 - 0.51 10.9 6.5 1.3 9.6 6.5 1.7 1 0 0 1 1 1 0 YtxH-like protein DUF4337 PF14235.6 EGD87531.2 - 0.95 9.6 4.5 1.5 9.0 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ATP-synt_B PF00430.18 EGD87531.2 - 1.3 9.1 8.7 2.1 8.4 8.7 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Borrelia_P83 PF05262.11 EGD87531.2 - 1.4 7.3 11.7 1.7 7.1 11.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein 2-oxoacid_dh PF00198.23 EGD87532.1 - 6e-75 251.7 0.0 7.5e-75 251.3 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGD87532.1 - 2.6e-17 62.4 0.4 2.6e-17 62.4 0.4 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EGD87532.1 - 1e-15 57.8 1.2 2.8e-15 56.3 0.4 2.2 2 0 0 2 2 2 1 e3 binding domain SopE_GEF PF07487.13 EGD87532.1 - 0.04 14.0 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 SopE GEF domain Biotin_lipoyl_2 PF13533.6 EGD87532.1 - 0.082 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like NAD_binding_7 PF13241.6 EGD87534.1 - 1.8e-31 108.6 0.2 2.8e-31 108.1 0.2 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EGD87534.1 - 1.1e-29 101.8 0.0 1.8e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EGD87534.1 - 7.6e-15 54.1 0.0 1.5e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 EGD87534.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 EGD87534.1 - 0.039 13.2 0.1 0.055 12.7 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EGD87534.1 - 0.17 11.2 1.9 0.29 10.5 0.1 1.9 1 1 1 2 2 2 0 ThiF family Pribosyltran_N PF13793.6 EGD87535.2 - 4.8e-44 149.0 0.1 4.6e-42 142.6 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGD87535.2 - 3.6e-36 124.9 0.1 1.6e-31 109.7 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGD87535.2 - 6.9e-11 41.9 0.0 1.8e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain CbiJ PF02571.14 EGD87535.2 - 0.077 12.5 0.1 0.34 10.4 0.0 2.1 2 1 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK Isochorismatase PF00857.20 EGD87536.1 - 1.7e-21 77.2 0.0 2e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Complex1_LYR PF05347.15 EGD87538.1 - 3.5e-05 23.8 0.3 7.8e-05 22.6 0.3 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGD87538.1 - 0.39 11.5 3.6 0.27 12.0 1.4 1.9 2 1 0 2 2 2 0 Complex1_LYR-like Ank_4 PF13637.6 EGD87539.1 - 2.9e-10 40.5 0.3 3.6e-08 33.8 0.2 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGD87539.1 - 3e-06 27.7 0.3 0.018 15.6 0.6 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGD87539.1 - 4.2e-05 23.8 1.7 0.0032 17.7 0.3 3.7 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD87539.1 - 0.0016 18.8 2.9 0.058 14.0 0.2 3.9 4 1 0 4 4 4 1 Ankyrin repeat KilA-N PF04383.13 EGD87539.1 - 0.0047 16.8 0.2 0.0047 16.8 0.2 2.7 2 1 0 2 2 2 1 KilA-N domain FapA PF03961.13 EGD87539.1 - 0.14 10.7 7.2 0.27 9.8 7.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 EGD87539.1 - 2.8 7.8 6.9 43 4.0 4.4 3.0 2 0 0 2 2 2 0 Septum formation initiator Ank PF00023.30 EGD87539.1 - 4.3 8.0 7.6 5.5 7.6 0.4 3.7 3 0 0 3 3 3 0 Ankyrin repeat TraT PF05818.12 EGD87540.1 - 0.0019 18.0 2.3 0.0042 16.8 2.3 1.6 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Rick_17kDa_Anti PF05433.15 EGD87540.1 - 0.0023 17.8 23.9 0.0078 16.1 24.1 1.9 1 1 0 1 1 1 1 Glycine zipper 2TM domain Med19 PF10278.9 EGD87540.1 - 0.65 9.9 12.5 1.1 9.2 12.5 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TFIIF_alpha PF05793.12 EGD87540.1 - 1.3 7.6 16.5 1.7 7.2 16.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Gly-zipper_Omp PF13488.6 EGD87540.1 - 1.8 8.7 24.0 3.1 7.9 23.0 2.0 1 1 0 1 1 1 0 Glycine zipper AP3D1 PF06375.11 EGD87540.1 - 2.3 8.5 15.5 3.9 7.7 15.5 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF1275 PF06912.11 EGD87541.2 - 1.8e-30 106.3 6.8 2.2e-30 106.1 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Oxidored_q6 PF01058.22 EGD87542.2 - 0.00033 20.5 0.0 0.00052 19.8 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit TPR_1 PF00515.28 EGD87543.1 - 6.2e-05 22.6 2.7 0.018 14.8 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGD87543.1 - 0.0013 18.4 0.0 0.006 16.2 0.0 2.3 1 0 0 1 1 1 1 TPR repeat TPR_7 PF13176.6 EGD87543.1 - 0.0056 16.6 3.7 0.35 11.0 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGD87543.1 - 0.0061 17.0 5.6 10 6.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGD87543.1 - 0.025 14.7 0.0 0.025 14.7 0.0 5.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGD87543.1 - 0.097 13.1 0.0 3.9 8.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGD87543.1 - 0.15 12.7 0.0 0.15 12.7 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGD87543.1 - 5.4 7.2 12.6 2.2 8.5 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.27 EGD87544.1 - 2.8e-47 160.7 0.1 4e-23 82.5 0.0 3.7 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 EGD87544.1 - 5.6e-30 103.2 0.9 2.3e-29 101.3 0.9 2.2 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 EGD87544.1 - 2.2e-17 63.8 0.8 0.0018 18.2 0.1 5.0 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGD87544.1 - 1.5e-16 60.6 0.0 1.5e-06 27.8 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGD87544.1 - 1.9e-09 38.3 3.9 0.00017 22.1 0.2 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EGD87544.1 - 8.4e-09 35.0 0.1 0.0041 16.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGD87544.1 - 2.8e-08 33.8 0.0 0.00015 21.8 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGD87544.1 - 9.7e-07 28.9 0.0 0.0057 16.7 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 EGD87544.1 - 9.8e-07 29.2 0.0 0.016 15.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGD87544.1 - 1e-06 29.2 2.1 0.27 11.6 0.0 4.6 5 0 0 5 5 4 2 AAA ATPase domain AAA PF00004.29 EGD87544.1 - 2e-06 28.3 0.2 0.19 12.2 0.0 5.1 6 0 0 6 6 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGD87544.1 - 6.3e-06 26.8 0.1 0.14 12.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGD87544.1 - 7.7e-06 26.2 0.0 0.12 12.7 0.0 3.5 4 0 0 4 4 2 2 AAA domain PduV-EutP PF10662.9 EGD87544.1 - 4.1e-05 23.3 0.0 0.067 12.9 0.0 3.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 EGD87544.1 - 4.8e-05 22.5 0.1 0.18 10.7 0.1 2.7 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 EGD87544.1 - 5.2e-05 23.5 0.1 0.25 11.4 0.0 3.2 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_15 PF13175.6 EGD87544.1 - 9.1e-05 22.3 0.1 0.77 9.4 0.0 3.5 3 1 1 4 4 4 2 AAA ATPase domain Dynamin_N PF00350.23 EGD87544.1 - 0.0001 22.4 0.1 0.0061 16.6 0.0 2.7 2 1 0 2 2 2 1 Dynamin family NACHT PF05729.12 EGD87544.1 - 0.00011 22.2 0.0 0.086 12.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 EGD87544.1 - 0.00016 22.0 0.0 0.76 10.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 EGD87544.1 - 0.00025 21.2 0.0 0.56 10.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EGD87544.1 - 0.0003 20.4 0.0 0.21 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGD87544.1 - 0.00064 19.5 0.0 1.1 8.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EGD87544.1 - 0.0012 18.8 0.0 3.4 7.7 0.0 3.3 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 EGD87544.1 - 0.0015 18.3 0.0 2.4 7.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 EGD87544.1 - 0.0015 17.8 0.0 1.7 7.7 0.0 2.9 3 0 0 3 3 3 1 G-protein alpha subunit NB-ARC PF00931.22 EGD87544.1 - 0.0017 17.6 0.8 0.095 11.9 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain SbcCD_C PF13558.6 EGD87544.1 - 0.0024 18.1 0.0 1.5 9.1 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EGD87544.1 - 0.0058 16.8 0.0 3.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGD87544.1 - 0.0072 16.1 0.0 3.9 7.2 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EGD87544.1 - 0.011 15.4 0.1 8.6 5.9 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MukB PF04310.12 EGD87544.1 - 0.012 15.4 0.1 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal Rad17 PF03215.15 EGD87544.1 - 0.015 15.3 0.0 1.3 8.9 0.0 2.8 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_PrkA PF08298.11 EGD87544.1 - 0.016 14.1 0.0 24 3.7 0.0 3.2 3 0 0 3 3 3 0 PrkA AAA domain CLP1_P PF16575.5 EGD87544.1 - 0.017 14.9 0.0 1.4 8.6 0.0 2.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase_2 PF01637.18 EGD87544.1 - 0.019 14.9 0.0 2.6 7.9 0.0 3.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EGD87544.1 - 0.023 14.5 0.0 13 5.5 0.0 3.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 EGD87544.1 - 0.023 14.5 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_7 PF12775.7 EGD87544.1 - 0.025 14.1 0.0 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 EGD87544.1 - 0.025 14.2 0.0 11 5.7 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase3 PF18751.1 EGD87544.1 - 0.036 14.0 0.0 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Mg_chelatase PF01078.21 EGD87544.1 - 0.037 13.4 0.4 3.2 7.1 0.0 3.2 4 0 0 4 4 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGD87544.1 - 0.04 13.9 0.0 17 5.4 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EGD87544.1 - 0.066 12.8 0.0 4.7 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGD87544.1 - 0.077 12.1 0.0 11 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF3437 PF11919.8 EGD87544.1 - 0.16 11.9 0.3 1.4 8.9 0.1 2.8 2 1 1 3 3 1 0 Domain of unknown function (DUF3437) HEAT PF02985.22 EGD87544.1 - 0.17 12.3 0.2 22 5.7 0.0 3.6 3 0 0 3 3 2 0 HEAT repeat Septin PF00735.18 EGD87544.1 - 0.2 10.9 2.1 3.5 6.8 0.0 3.1 4 0 0 4 4 4 0 Septin HEAT_EZ PF13513.6 EGD87544.1 - 0.27 11.8 4.5 15 6.2 0.0 4.8 4 1 2 6 6 4 0 HEAT-like repeat Mu-like_Pro PF10123.9 EGD87544.1 - 0.28 10.7 8.4 0.84 9.1 8.4 1.9 1 0 0 1 1 1 0 Mu-like prophage I protein AAA_13 PF13166.6 EGD87544.1 - 3.4 6.2 9.0 3 6.4 0.0 3.3 5 0 0 5 5 3 0 AAA domain Claudin_2 PF13903.6 EGD87545.2 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction GET2 PF08690.10 EGD87545.2 - 0.18 11.4 2.8 0.17 11.5 0.3 1.8 1 1 1 2 2 2 0 GET complex subunit GET2 DUF3357 PF11837.8 EGD87545.2 - 0.2 12.1 2.5 0.38 11.2 0.2 2.6 2 2 1 3 3 3 0 Domain of unknown function (DUF3357) U1snRNP70_N PF12220.8 EGD87545.2 - 0.29 11.8 2.8 0.21 12.3 0.9 1.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Orf78 PF06024.12 EGD87545.2 - 0.61 10.4 4.7 5 7.5 4.7 2.2 1 1 0 1 1 1 0 Orf78 (ac78) TMEM132D_C PF15706.5 EGD87545.2 - 1.5 8.6 4.1 0.85 9.4 0.6 2.1 2 1 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EPO_TPO PF00758.18 EGD87545.2 - 3.4 7.7 5.2 0.67 10.0 0.9 2.0 1 1 1 2 2 2 0 Erythropoietin/thrombopoietin UCH PF00443.29 EGD87548.1 - 6.6e-70 235.5 0.0 1e-69 234.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGD87548.1 - 1e-12 48.5 0.0 2.7e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 EGD87548.1 - 4.6e-12 46.2 0.0 5.3e-05 23.0 0.0 3.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 EGD87548.1 - 0.001 18.8 0.0 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal Zn_ribbon_SprT PF17283.2 EGD87548.1 - 2.3 8.2 3.5 0.83 9.6 0.3 1.9 2 0 0 2 2 2 0 SprT-like zinc ribbon domain PX PF00787.24 EGD87549.2 - 8e-19 67.7 0.0 3.4e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EGD87549.2 - 7.1e-06 25.7 4.2 0.0039 16.8 0.3 2.2 2 0 0 2 2 2 2 Vps5 C terminal like SARAF PF06682.12 EGD87550.1 - 0.028 14.1 4.0 0.054 13.1 4.0 1.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4381 PF14316.6 EGD87550.1 - 0.032 14.5 5.2 0.033 14.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 EGD87550.1 - 0.47 11.4 1.7 1.9 9.4 1.7 2.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ctr PF04145.15 EGD87550.1 - 2 9.1 6.2 12 6.5 6.2 2.1 1 1 0 1 1 1 0 Ctr copper transporter family Tim17 PF02466.19 EGD87552.1 - 8.5e-28 97.0 3.8 1.2e-27 96.5 3.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.25 EGD87554.2 - 3.4e-44 151.2 0.0 4.8e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87554.2 - 3.4e-28 98.6 0.0 4.7e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD87554.2 - 0.05 12.4 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EGD87554.2 - 0.11 11.9 0.2 1.2 8.4 0.1 2.3 2 1 0 2 2 2 0 Kinase-like UPF0547 PF10571.9 EGD87555.1 - 0.054 13.6 0.4 0.11 12.6 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 ILVD_EDD PF00920.21 EGD87557.1 - 1.6e-209 696.9 0.2 1.9e-209 696.6 0.2 1.1 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 EGD87557.1 - 0.1 12.8 0.1 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain RAI16-like PF10257.9 EGD87560.2 - 4.4e-79 266.0 0.0 6.2e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein BTB PF00651.31 EGD87561.1 - 0.00049 20.3 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain CBFD_NFYB_HMF PF00808.23 EGD87562.1 - 4.2e-14 52.6 1.0 6.5e-14 52.0 1.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGD87562.1 - 0.079 13.3 19.5 0.028 14.8 14.2 2.9 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 PAT1 PF09770.9 EGD87562.1 - 0.22 9.8 33.2 0.25 9.5 33.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.6 EGD87562.1 - 4.4 6.6 6.5 7.7 5.8 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C3HC4_3 PF13920.6 EGD87563.1 - 0.0017 18.1 10.1 0.0031 17.3 10.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Transposase_21 PF02992.14 EGD87563.1 - 0.19 11.0 0.0 0.48 9.6 0.0 1.6 1 0 0 1 1 1 0 Transposase family tnp2 WD40_4 PF16300.5 EGD87564.2 - 4.8e-20 71.2 0.2 1e-19 70.1 0.2 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EGD87564.2 - 5.7e-17 61.8 4.4 0.00042 21.1 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1899 PF08953.11 EGD87564.2 - 1.4e-10 40.9 0.0 3.2e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 EGD87564.2 - 4.2e-07 30.2 0.0 0.002 18.4 0.1 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD87564.2 - 0.019 13.6 0.2 0.048 12.3 0.2 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 eIF2A PF08662.11 EGD87564.2 - 0.025 14.5 0.0 1.2 9.0 0.0 2.5 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A SlyX PF04102.12 EGD87564.2 - 0.034 14.8 0.2 0.072 13.7 0.2 1.6 1 0 0 1 1 1 0 SlyX FAM76 PF16046.5 EGD87564.2 - 1.4 8.2 4.2 1.8 7.8 4.2 1.1 1 0 0 1 1 1 0 FAM76 protein Kinesin PF00225.23 EGD87565.2 - 8.7e-108 360.2 1.4 8.7e-108 360.2 1.4 2.1 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGD87565.2 - 3.3e-60 202.4 0.0 8.4e-60 201.0 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding MBR1 PF17058.5 EGD87565.2 - 0.031 14.6 0.3 0.031 14.6 0.3 2.6 2 1 1 3 3 3 0 Mitochondrial biogenesis regulation protein 1 AAA_16 PF13191.6 EGD87565.2 - 0.052 13.9 0.0 0.052 13.9 0.0 3.4 2 1 1 3 3 3 0 AAA ATPase domain Sugar_tr PF00083.24 EGD87566.2 - 1.1e-51 176.1 8.9 1.3e-51 175.9 8.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter SYS1 PF09801.9 EGD87566.2 - 0.03 14.5 1.1 0.074 13.2 0.3 2.0 2 0 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network Peptidase_S8 PF00082.22 EGD87568.1 - 1.9e-27 96.3 18.1 4.7e-27 95.0 18.1 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGD87568.1 - 6e-15 55.7 0.5 9.5e-15 55.0 0.5 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3553 PF12073.8 EGD87568.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) Aminotran_4 PF01063.19 EGD87570.1 - 1.6e-26 93.6 0.0 2e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV TPR_1 PF00515.28 EGD87571.1 - 1.6e-41 138.4 34.6 4.9e-06 26.1 0.1 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 EGD87571.1 - 1.9e-39 130.6 34.0 7.9e-05 22.5 0.1 11.6 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 EGD87571.1 - 7.2e-24 82.0 26.8 0.00031 20.7 0.0 10.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGD87571.1 - 2.8e-21 75.9 21.8 3.7e-06 27.5 0.1 7.0 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGD87571.1 - 2.7e-20 71.7 29.9 9e-07 28.5 0.1 9.2 7 2 3 10 10 10 5 TPR repeat TPR_17 PF13431.6 EGD87571.1 - 8.1e-18 63.5 17.9 0.012 16.0 0.0 9.0 8 2 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 EGD87571.1 - 1.1e-16 60.9 36.4 0.00025 21.3 2.7 8.6 3 2 7 10 10 10 9 Tetratricopeptide repeat TPR_9 PF13371.6 EGD87571.1 - 8.1e-14 51.5 16.4 7.6e-06 26.0 0.2 6.5 4 2 4 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGD87571.1 - 8.1e-14 51.9 30.9 5.5e-06 26.8 2.4 8.0 6 2 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGD87571.1 - 3.2e-13 48.7 22.7 0.0097 15.9 0.6 9.8 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGD87571.1 - 2.9e-11 43.2 25.8 0.038 14.8 1.1 10.1 3 3 9 12 12 11 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGD87571.1 - 3.3e-07 30.0 28.3 0.052 13.4 1.0 9.6 11 0 0 11 11 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGD87571.1 - 6e-07 29.6 19.4 0.087 13.1 0.4 5.9 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EGD87571.1 - 3.2e-06 26.8 9.9 8.4e-05 22.1 4.6 4.1 2 1 2 4 4 4 2 MalT-like TPR region SHNi-TPR PF10516.9 EGD87571.1 - 0.00013 21.3 14.6 0.18 11.3 0.0 7.7 8 0 0 8 8 8 1 SHNi-TPR MAS20 PF02064.15 EGD87571.1 - 0.0015 18.6 6.6 0.012 15.7 0.3 4.0 4 1 1 5 5 5 1 MAS20 protein import receptor TAF1_subA PF14929.6 EGD87571.1 - 0.0034 16.9 0.9 0.0087 15.5 0.4 1.9 2 1 0 2 2 2 1 TAF RNA Polymerase I subunit A DUF3856 PF12968.7 EGD87571.1 - 0.0084 16.2 5.0 7.2 6.7 0.0 4.9 4 3 0 4 4 4 0 Domain of Unknown Function (DUF3856) Wzy_C_2 PF11846.8 EGD87571.1 - 0.021 14.7 0.4 9.9 6.0 0.0 3.5 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Sel1 PF08238.12 EGD87571.1 - 0.028 15.1 6.2 0.92 10.3 0.1 4.2 4 0 0 4 4 2 0 Sel1 repeat MIT PF04212.18 EGD87571.1 - 0.04 14.0 14.4 9 6.4 0.3 6.6 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain Transglut_prok PF09017.10 EGD87571.1 - 0.062 12.6 1.3 0.96 8.7 0.0 2.2 2 0 0 2 2 2 0 Microbial transglutaminase FAT PF02259.23 EGD87571.1 - 0.12 11.6 3.2 8.5 5.5 0.3 3.1 3 0 0 3 3 3 0 FAT domain TPR_4 PF07721.14 EGD87571.1 - 0.22 12.2 6.9 1.7e+02 3.3 0.2 6.4 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGD87571.1 - 0.31 11.8 29.4 9.6 7.1 0.9 9.3 11 0 0 11 11 9 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGD87571.1 - 0.63 10.5 3.8 26 5.2 0.1 3.9 3 2 0 3 3 3 0 Alkyl sulfatase dimerisation DNApol_Exo PF18136.1 EGD87571.1 - 1.3 8.1 4.6 13 4.8 0.0 2.3 1 1 1 2 2 2 0 DNA mitochondrial polymerase exonuclease domain DUF4519 PF15012.6 EGD87571.1 - 7.7 6.8 6.7 19 5.5 6.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) NARP1 PF12569.8 EGD87571.1 - 8.1 5.2 28.9 0.095 11.6 0.3 4.6 2 2 1 4 4 4 0 NMDA receptor-regulated protein 1 TackOD1 PF18551.1 EGD87573.1 - 0.044 13.5 0.2 0.052 13.2 0.2 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 I-EGF_1 PF18372.1 EGD87573.1 - 0.49 10.5 7.2 0.22 11.6 2.9 2.2 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 DNA_RNApol_7kD PF03604.13 EGD87573.1 - 3.4 7.4 8.7 5.3 6.8 0.2 2.7 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Sec1 PF00995.23 EGD87574.1 - 1.5e-127 427.3 0.0 1.8e-127 427.0 0.0 1.1 1 0 0 1 1 1 1 Sec1 family zf_CCCH_4 PF18345.1 EGD87575.2 - 2.9e-07 30.3 3.7 4.9e-07 29.6 3.7 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGD87575.2 - 1.9e-05 24.3 1.9 3e-05 23.7 1.9 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EGD87575.2 - 0.00012 21.9 0.5 0.00019 21.3 0.5 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EGD87575.2 - 0.00041 20.7 1.8 0.00067 20.0 1.8 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EGD87575.2 - 0.0078 16.9 2.5 0.0078 16.9 2.5 2.1 2 0 0 2 2 2 1 Torus domain zf-CCCH_3 PF15663.5 EGD87575.2 - 0.012 15.8 0.1 0.028 14.6 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger containing family TFIIA PF03153.13 EGD87575.2 - 8.1 6.3 38.8 0.36 10.8 33.3 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HORMA PF02301.18 EGD87576.1 - 1.8e-34 119.2 0.0 2e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EGD87576.1 - 0.0021 18.0 0.2 0.0097 15.9 0.2 1.9 1 1 0 1 1 1 1 Autophagy-related protein 101 DUF2660 PF10859.8 EGD87576.1 - 0.024 15.1 0.1 0.099 13.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) bacHORMA_2 PF18173.1 EGD87576.1 - 0.061 13.2 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial HORMA domain 2 GTP_EFTU PF00009.27 EGD87577.1 - 3.9e-51 173.4 0.0 6e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EGD87577.1 - 8.2e-44 148.1 3.3 1.3e-43 147.5 3.3 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EGD87577.1 - 1.2e-20 73.3 0.0 2.3e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.22 EGD87577.1 - 5.7e-06 26.0 0.0 4e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Ras family GTP_EFTU_D2 PF03144.25 EGD87577.1 - 3.5e-05 24.1 0.7 7.1e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGD87577.1 - 4.2e-05 23.6 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EGD87577.1 - 0.00057 19.9 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 EGD87577.1 - 0.0046 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 EGD87577.1 - 0.0065 15.9 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 EGD87577.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Snurportin1 PF11538.8 EGD87577.1 - 0.097 12.9 1.3 0.25 11.5 1.3 1.7 1 0 0 1 1 1 0 Snurportin1 Methyltransf_25 PF13649.6 EGD87579.1 - 1.5e-11 44.8 0.0 2.6e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD87579.1 - 7.1e-10 39.4 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD87579.1 - 2.4e-09 37.8 0.0 4.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD87579.1 - 1.2e-07 31.7 0.0 2.5e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD87579.1 - 0.01 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGD87579.1 - 0.013 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGD87579.1 - 0.055 13.0 0.0 0.11 12.1 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase small domain DUF3328 PF11807.8 EGD87580.2 - 5.2e-17 62.4 2.6 1.7e-13 50.9 0.5 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) FAD_binding_4 PF01565.23 EGD87582.1 - 2.9e-20 72.4 3.0 4.5e-20 71.8 3.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGD87582.1 - 2e-10 40.6 0.0 3.8e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Rax2 PF12768.7 EGD87582.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Trypsin_2 PF13365.6 EGD87583.2 - 1.8e-06 28.9 0.1 5.6e-06 27.3 0.1 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.11 EGD87583.2 - 0.00065 18.3 0.0 0.08 11.4 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S29 PF02907.15 EGD87583.2 - 0.008 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Tfb5 PF06331.12 EGD87584.1 - 1.2e-18 66.8 0.0 1.7e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 ECH_1 PF00378.20 EGD87585.2 - 2e-39 135.4 0.0 3.1e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGD87585.2 - 4.6e-26 92.1 0.0 3.3e-25 89.3 0.0 1.7 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase 2OG-FeII_Oxy_2 PF13532.6 EGD87586.1 - 1.9e-27 96.7 0.1 3.6e-27 95.8 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 EGD87586.1 - 7.4e-22 78.4 0.0 4.1e-15 56.4 0.0 2.3 2 0 0 2 2 2 2 Isochorismatase family GST_N_3 PF13417.6 EGD87586.1 - 0.0052 17.2 0.0 0.027 14.9 0.0 2.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGD87586.1 - 0.01 16.0 0.0 0.034 14.3 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 EGD87586.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GST_N PF02798.20 EGD87586.1 - 0.019 15.3 0.0 0.087 13.2 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGD87586.1 - 0.083 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IlvN PF07991.12 EGD87587.2 - 2.5e-45 154.0 0.0 4e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EGD87587.2 - 8.2e-41 139.7 0.1 1.6e-40 138.7 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 EGD87587.2 - 0.082 13.5 0.2 0.43 11.2 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EGD87587.2 - 0.092 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Amidoligase_2 PF12224.8 EGD87588.2 - 1.2e-11 44.8 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme GGACT PF06094.12 EGD87589.1 - 6e-06 26.9 0.0 7.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like PALP PF00291.25 EGD87590.1 - 3.3e-63 213.8 0.1 4.4e-63 213.4 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGD87590.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Rad51 PF08423.11 EGD87591.1 - 0.0032 16.8 0.0 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Rad51 TAF8_C PF10406.9 EGD87593.1 - 3.9e-21 75.3 0.5 1.3e-20 73.7 0.5 2.0 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 EGD87593.1 - 5.5e-06 26.3 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated COX6C PF02937.15 EGD87594.1 - 0.013 15.6 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc UQ_con PF00179.26 EGD87595.1 - 7.9e-36 122.8 0.0 1e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGD87595.1 - 0.091 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Chitin_synth_1 PF01644.17 EGD87596.1 - 4.7e-69 231.5 0.0 6.8e-69 231.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGD87596.1 - 2.7e-28 97.7 0.0 5.1e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGD87596.1 - 1.1e-22 80.4 0.1 4e-18 65.3 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGD87596.1 - 8.6e-09 35.6 0.1 8.6e-09 35.6 0.1 2.6 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Psu PF07455.11 EGD87596.1 - 0.0032 17.1 0.0 3.1 7.4 0.0 2.3 2 0 0 2 2 2 2 Phage polarity suppression protein (Psu) Opy2 PF09463.10 EGD87598.2 - 6.2e-09 36.0 19.9 9.6e-09 35.4 19.9 1.3 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.10 EGD87598.2 - 0.00024 20.4 0.1 0.00057 19.2 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Beta-APP PF03494.13 EGD87598.2 - 0.051 13.4 0.7 0.11 12.4 0.7 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) MAPEG PF01124.18 EGD87598.2 - 0.063 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 MAPEG family Methyltransf_23 PF13489.6 EGD87600.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD87600.1 - 1.2e-05 25.9 0.0 2.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD87600.1 - 5.5e-05 23.7 0.0 0.00011 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD87600.1 - 0.0019 18.9 0.0 0.0038 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD87600.1 - 0.0069 16.2 0.0 0.017 14.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EGD87600.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TehB PF03848.14 EGD87600.1 - 0.052 12.9 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB HET PF06985.11 EGD87602.2 - 2.3e-12 47.5 8.4 1.8e-10 41.3 2.9 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) C1_2 PF03107.16 EGD87602.2 - 0.00016 22.0 3.9 0.00016 22.0 3.9 2.4 2 0 0 2 2 2 1 C1 domain ZZ PF00569.17 EGD87602.2 - 0.00022 21.0 7.8 0.00022 21.0 7.8 2.5 2 0 0 2 2 2 1 Zinc finger, ZZ type HAD PF12710.7 EGD87602.2 - 0.14 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase GrpE PF01025.19 EGD87603.1 - 0.84 9.3 4.7 1.3 8.6 4.7 1.3 1 0 0 1 1 1 0 GrpE Pkinase_Tyr PF07714.17 EGD87604.1 - 3.3e-15 56.1 0.0 4.8e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGD87604.1 - 1.8e-14 53.7 0.0 4e-14 52.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EGD87604.1 - 0.00053 19.6 0.0 0.0019 17.9 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EGD87604.1 - 0.0025 17.8 0.2 0.0075 16.2 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGD87604.1 - 0.01 15.5 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EGD87604.1 - 0.027 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phosphoesterase PF04185.14 EGD87605.2 - 1.6e-41 142.7 0.0 2.9e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.15 EGD87607.1 - 7.1e-45 151.9 1.1 3e-42 143.4 0.3 3.5 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGD87607.1 - 1.8e-34 118.4 9.1 8.1e-34 116.3 2.1 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGD87607.1 - 1.8e-16 60.7 0.0 7.2e-15 55.5 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase WW PF00397.26 EGD87608.1 - 1.8e-06 27.9 0.4 4.2e-06 26.7 0.4 1.7 1 0 0 1 1 1 1 WW domain Glt_symporter PF03616.14 EGD87608.1 - 0.16 10.7 0.8 0.21 10.3 0.8 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter WD40 PF00400.32 EGD87613.2 - 1.9e-30 104.5 11.1 1.7e-08 34.9 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD87613.2 - 0.00012 22.3 0.0 2 8.7 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD87613.2 - 0.0068 15.1 0.0 0.014 14.1 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 CHAP PF05257.16 EGD87613.2 - 0.049 14.2 0.0 2.1 9.0 0.0 2.5 2 0 0 2 2 2 0 CHAP domain Nucleoporin_N PF08801.11 EGD87613.2 - 0.13 11.0 0.1 8.7 5.0 0.0 2.6 2 1 0 2 2 2 0 Nup133 N terminal like zf-C2H2 PF00096.26 EGD87614.1 - 2.5e-08 33.9 13.2 0.00055 20.2 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EGD87614.1 - 7.9e-05 22.9 0.1 0.00015 22.0 0.1 1.4 1 0 0 1 1 1 1 Aberrant zinc-finger Spc29 PF17082.5 EGD87614.1 - 0.00044 20.2 0.2 0.00077 19.4 0.2 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 APC_N_CC PF16689.5 EGD87614.1 - 0.0084 16.2 0.1 0.02 15.0 0.1 1.6 1 0 0 1 1 1 1 Coiled-coil N-terminus of APC, dimerisation domain zf-H2C2_2 PF13465.6 EGD87614.1 - 0.015 15.7 10.2 3.8 8.1 0.5 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGD87614.1 - 0.026 15.4 8.3 7.5 7.7 0.1 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger ATG16 PF08614.11 EGD87614.1 - 0.033 14.4 0.1 0.062 13.5 0.1 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Cep57_MT_bd PF06657.13 EGD87614.1 - 0.14 12.6 2.5 8.3 6.9 0.1 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Transpos_assoc PF13963.6 EGD87614.1 - 0.15 12.4 1.3 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Transposase-associated domain MPS2 PF17060.5 EGD87614.1 - 0.31 10.3 0.5 0.43 9.8 0.5 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Lebercilin PF15619.6 EGD87614.1 - 0.61 9.7 4.9 0.55 9.9 1.0 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DSPc PF00782.20 EGD87615.1 - 6.5e-12 45.4 0.0 1.4e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGD87615.1 - 0.00066 19.9 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Ribosomal_L5e PF17144.4 EGD87616.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal large subunit proteins 60S L5, and 50S L18 End3 PF12761.7 EGD87618.1 - 1.1e-72 244.3 1.5 1.5e-72 243.9 1.5 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EGD87618.1 - 2.4e-51 172.0 0.1 5e-49 164.6 0.0 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EGD87618.1 - 8.5e-08 31.2 0.2 2.6e-07 29.7 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGD87618.1 - 1.2e-06 28.9 0.7 6.1e-06 26.6 0.1 2.5 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EGD87618.1 - 9.6e-05 22.0 0.5 0.00043 20.0 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EGD87618.1 - 0.0016 18.2 0.2 0.0053 16.6 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGD87618.1 - 0.0029 17.0 1.0 0.0094 15.4 0.2 2.2 2 0 0 2 2 2 1 EF hand NPV_P10 PF05531.12 EGD87618.1 - 0.016 15.7 0.2 0.23 11.9 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SKA1 PF07160.12 EGD87618.1 - 0.027 14.3 0.3 0.053 13.4 0.3 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF4407 PF14362.6 EGD87618.1 - 0.075 12.4 5.2 0.11 11.9 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.11 EGD87618.1 - 0.88 9.7 4.6 2.3 8.3 0.6 2.7 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 EGD87618.1 - 1.6 7.6 11.5 0.26 10.1 4.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Wtap PF17098.5 EGD87618.1 - 2.3 8.1 9.6 2 8.3 7.8 1.7 2 0 0 2 2 2 0 WTAP/Mum2p family Sec2p PF06428.11 EGD87618.1 - 2.4 8.2 10.2 7.6 6.6 0.9 2.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Med9 PF07544.13 EGD87618.1 - 3.4 7.8 5.8 0.48 10.6 0.2 2.4 3 0 0 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 Mit_KHE1 PF10173.9 EGD87619.1 - 5.6e-66 222.3 0.3 8e-66 221.8 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related ABC2_membrane_4 PF12730.7 EGD87619.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein MARVEL PF01284.23 EGD87620.1 - 0.0039 17.2 2.5 0.0069 16.4 2.5 1.4 1 0 0 1 1 1 1 Membrane-associating domain KcnmB2_inactiv PF09303.10 EGD87620.1 - 0.0096 15.7 0.4 0.032 14.0 0.4 1.9 1 0 0 1 1 1 1 KCNMB2, ball and chain domain DUF1418 PF07214.12 EGD87620.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) PAP1 PF08601.10 EGD87620.1 - 0.23 11.1 10.8 0.32 10.7 10.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Cupin_1 PF00190.22 EGD87621.1 - 1.1e-10 41.4 0.1 1.5e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EGD87621.1 - 4.6e-08 32.6 0.1 6.9e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Cupin domain ARD PF03079.14 EGD87621.1 - 0.00035 20.8 0.0 0.00047 20.4 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 EGD87621.1 - 0.00053 19.8 0.1 0.00065 19.5 0.1 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EGD87621.1 - 0.002 18.0 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cullin PF00888.22 EGD87622.2 - 4.2e-185 616.9 5.9 5.2e-185 616.6 5.9 1.0 1 0 0 1 1 1 1 Cullin family Avl9 PF09794.9 EGD87623.1 - 8.8e-144 478.9 0.0 1.2e-143 478.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 EGD87623.1 - 6.2e-08 32.6 0.1 0.00048 20.1 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 EGD87623.1 - 2.4e-07 30.7 6.9 6.3e-06 26.0 0.5 3.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 EGD87623.1 - 3.6 8.1 5.7 3.7 8.0 0.0 2.9 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Menin PF05053.13 EGD87623.1 - 3.9 5.7 11.3 5.5 5.2 11.3 1.1 1 0 0 1 1 1 0 Menin APH PF01636.23 EGD87624.2 - 7e-07 29.4 0.0 7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGD87625.1 - 3.2e-67 226.7 0.0 4.1e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87625.1 - 2.1e-32 112.4 0.0 2.9e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGD87625.1 - 1.3e-05 24.3 0.1 1.9e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGD87625.1 - 9.6e-05 21.8 0.1 0.0003 20.2 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGD87625.1 - 0.00046 19.6 0.0 0.026 13.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EGD87625.1 - 0.00072 19.6 0.0 0.0026 17.7 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGD87625.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGD87625.1 - 0.042 13.4 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family G-alpha PF00503.20 EGD87627.2 - 9.3e-101 337.5 0.5 1.1e-100 337.3 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGD87627.2 - 5.1e-09 35.8 0.8 4.5e-08 32.8 0.4 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family Phosphorylase PF00343.20 EGD87628.1 - 0 1060.3 0.0 0 1060.1 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase APH PF01636.23 EGD87629.1 - 2.5e-14 53.8 0.2 4.4e-14 53.0 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGD87629.1 - 0.00018 21.0 0.7 0.22 10.9 0.0 3.1 4 0 0 4 4 4 2 Protein kinase domain Choline_kinase PF01633.20 EGD87629.1 - 0.0019 17.8 0.1 0.0033 17.1 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EGD87629.1 - 0.019 14.5 0.3 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 RIO1 family DnaGprimase_HBD PF16730.5 EGD87629.1 - 0.13 12.3 0.1 3.4 7.8 0.0 2.3 2 0 0 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain p450 PF00067.22 EGD87630.2 - 6.2e-62 209.9 0.0 7.4e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane_2 PF06472.15 EGD87631.1 - 2.2e-103 345.4 1.1 3e-103 344.9 1.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGD87631.1 - 1.6e-18 67.5 0.0 2.9e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGD87631.1 - 5.7e-05 23.1 0.1 0.00017 21.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGD87631.1 - 0.0048 17.4 0.1 0.013 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGD87631.1 - 0.0094 15.7 0.0 0.041 13.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGD87631.1 - 0.033 13.6 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGD87631.1 - 0.053 13.9 0.2 0.42 11.0 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 EGD87631.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 EGD87631.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_15 PF13175.6 EGD87631.1 - 0.18 11.5 0.1 0.5 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain LRR_6 PF13516.6 EGD87632.1 - 0.0015 18.5 2.7 2.4 8.4 0.0 5.3 6 0 0 6 6 6 1 Leucine Rich repeat DUF3135 PF11333.8 EGD87632.1 - 0.0039 17.4 0.9 0.18 12.1 0.1 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3135) Ribosomal_L5e PF17144.4 EGD87633.1 - 5.4e-80 267.1 0.2 7.7e-80 266.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EGD87633.1 - 9.3e-34 116.2 2.7 9.3e-34 116.2 2.7 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HAD_2 PF13419.6 EGD87634.2 - 8e-07 29.3 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGD87634.2 - 0.00067 20.0 0.0 0.0009 19.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGD87634.2 - 0.0084 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like SlyX PF04102.12 EGD87635.2 - 0.019 15.6 1.5 0.041 14.5 1.1 1.8 2 0 0 2 2 2 0 SlyX FTA4 PF13093.6 EGD87636.2 - 2.6e-56 190.7 0.0 3.9e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 BPL_N PF09825.9 EGD87636.2 - 0.018 14.1 1.2 0.029 13.5 1.2 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF1664 PF07889.12 EGD87636.2 - 0.02 14.9 0.7 0.08 13.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) F-box PF00646.33 EGD87638.1 - 4.1e-06 26.5 0.4 1.3e-05 25.0 0.4 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGD87638.1 - 2.5e-05 24.1 0.4 5.7e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 F-box-like AA_permease PF00324.21 EGD87639.2 - 2.8e-21 75.7 10.3 3.3e-21 75.4 10.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD87639.2 - 0.0032 16.4 5.3 0.0042 16.0 5.3 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_YtrH PF14034.6 EGD87639.2 - 0.15 12.2 2.8 0.26 11.5 2.8 1.2 1 0 0 1 1 1 0 Sporulation protein YtrH RHS_repeat PF05593.14 EGD87644.2 - 0.027 15.0 0.6 0.11 13.1 0.0 2.1 2 1 0 2 2 2 0 RHS Repeat APH PF01636.23 EGD87645.2 - 1.2e-07 31.9 0.1 1.9e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans PF04082.18 EGD87646.2 - 3.5e-05 23.0 0.2 4.8e-05 22.5 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_30 PF13556.6 EGD87646.2 - 0.23 11.3 1.4 0.8 9.6 0.0 2.5 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain Coatomer_E PF04733.14 EGD87647.1 - 3.5e-63 213.7 7.0 4e-63 213.5 7.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EGD87647.1 - 5.5e-09 36.4 17.7 0.00032 21.1 2.7 4.5 2 1 3 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGD87647.1 - 3.2e-08 33.7 4.3 0.0085 16.3 0.8 3.3 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGD87647.1 - 1.6e-07 31.9 18.1 0.0013 19.3 2.3 4.5 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGD87647.1 - 2.3e-05 24.8 15.2 0.061 14.2 0.0 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGD87647.1 - 0.00023 21.4 12.4 0.051 13.9 1.4 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGD87647.1 - 0.00035 21.0 0.7 0.28 11.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGD87647.1 - 0.007 16.2 1.9 0.78 9.7 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Peptidase_S11 PF00768.20 EGD87647.1 - 0.0091 15.5 0.2 0.012 15.1 0.2 1.3 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase TPR_15 PF13429.6 EGD87647.1 - 0.013 14.7 7.7 0.031 13.5 1.3 2.9 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGD87647.1 - 0.017 15.2 13.6 0.11 12.7 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGD87647.1 - 0.097 12.8 4.0 0.53 10.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 EGD87647.1 - 0.25 11.4 5.8 0.47 10.5 2.6 2.8 1 1 2 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_10 PF13374.6 EGD87647.1 - 0.36 10.8 6.8 32 4.6 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGD87647.1 - 2.3 9.1 19.7 2.6 8.9 0.1 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGD87647.1 - 4.8 7.6 11.1 19 5.7 3.6 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 EGD87648.1 - 3.8e-24 85.7 0.0 1.3e-23 84.0 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGD87648.1 - 3.6e-22 78.8 0.0 4.4e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EGD87648.1 - 0.031 13.8 0.0 0.22 10.9 0.0 2.2 3 0 0 3 3 3 0 Prolyl oligopeptidase family COesterase PF00135.28 EGD87648.1 - 0.14 11.0 0.2 9.1 5.0 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family DUF2974 PF11187.8 EGD87648.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PMI_typeI PF01238.21 EGD87649.1 - 1.6e-147 491.6 0.0 1.9e-147 491.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 EGD87649.1 - 0.096 12.6 0.0 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain Cas_TM1802 PF09484.10 EGD87649.1 - 0.13 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) DUF1325 PF07039.11 EGD87650.1 - 3.3e-34 117.8 0.0 1e-33 116.3 0.0 1.9 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 EGD87650.1 - 0.0038 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain MS_channel PF00924.18 EGD87650.1 - 0.23 11.0 0.1 0.35 10.4 0.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel Spt20 PF12090.8 EGD87650.1 - 0.61 9.7 8.1 1.4 8.5 8.1 1.7 1 0 0 1 1 1 0 Spt20 family Inhibitor_I53 PF11714.8 EGD87650.1 - 6.3 7.1 7.7 1.6 9.0 4.0 2.0 2 0 0 2 2 2 0 Thrombin inhibitor Madanin GTP_cyclohydro2 PF00925.20 EGD87651.1 - 2.8e-57 192.9 0.0 3.8e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II Methyltransf_23 PF13489.6 EGD87652.1 - 1.1e-15 57.9 0.0 1.5e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD87652.1 - 1.3e-12 48.1 0.0 8.8e-12 45.5 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD87652.1 - 4.6e-12 46.5 0.0 1.1e-11 45.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD87652.1 - 7e-12 45.4 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD87652.1 - 2.6e-11 44.1 0.0 5.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EGD87652.1 - 0.00051 19.2 0.0 0.0025 17.0 0.0 1.9 1 1 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.18 EGD87652.1 - 0.0014 18.0 0.0 0.0067 15.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 EGD87652.1 - 0.022 14.3 0.0 0.13 11.8 0.0 2.0 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_19 PF04672.12 EGD87652.1 - 0.033 13.7 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl methyltransferase MTS PF05175.14 EGD87652.1 - 0.084 12.4 0.0 0.28 10.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Fungal_trans PF04082.18 EGD87653.1 - 3.6e-10 39.3 0.0 9.7e-10 37.9 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD87653.1 - 1.7e-07 31.2 6.9 1.7e-07 31.2 6.9 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.8 EGD87654.2 - 5.1e-23 81.4 1.4 8.5e-23 80.7 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) G_path_suppress PF15991.5 EGD87654.2 - 0.0049 17.1 7.4 0.005 17.0 6.3 1.5 1 1 0 1 1 1 1 G-protein pathway suppressor BMFP PF04380.13 EGD87654.2 - 0.047 14.2 0.4 0.1 13.1 0.4 1.6 1 0 0 1 1 1 0 Membrane fusogenic activity bZIP_1 PF00170.21 EGD87654.2 - 0.12 12.5 11.3 0.077 13.1 8.2 2.0 1 1 1 2 2 2 0 bZIP transcription factor Actin PF00022.19 EGD87655.2 - 3.3e-103 345.5 0.0 2.4e-102 342.6 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGD87655.2 - 0.056 12.3 0.0 0.37 9.6 0.0 2.3 1 1 0 1 1 1 0 MreB/Mbl protein EamA PF00892.20 EGD87656.1 - 2.1e-09 37.7 29.3 1.5e-05 25.2 1.2 2.8 3 0 0 3 3 3 2 EamA-like transporter family Aldo_ket_red PF00248.21 EGD87657.1 - 4.6e-54 183.6 0.0 5.2e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tubulin PF00091.25 EGD87658.2 - 2.6e-66 223.6 0.0 3.8e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 EGD87658.2 - 1.5e-07 31.7 0.0 3.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGD87658.2 - 0.033 13.9 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 EGD87658.2 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Tubulin_C PF03953.17 EGD87659.2 - 2.6e-43 147.2 0.1 3.3e-43 146.8 0.1 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain Hrs_helical PF12210.8 EGD87659.2 - 0.026 15.1 0.1 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Citrate_bind PF16114.5 EGD87659.2 - 0.13 11.7 0.0 6.5 6.2 0.0 2.2 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding Aa_trans PF01490.18 EGD87660.1 - 1.3e-37 129.5 39.4 1.6e-37 129.2 39.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Crystall PF00030.19 EGD87661.1 - 0.0018 18.5 0.0 0.0024 18.0 0.0 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin DUF883 PF05957.13 EGD87662.2 - 0.017 15.7 0.1 0.019 15.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EGD87662.2 - 0.017 15.6 2.4 0.021 15.4 2.4 1.2 1 0 0 1 1 1 0 YtxH-like protein HOIP-UBA PF16678.5 EGD87662.2 - 0.02 14.9 0.2 0.022 14.8 0.2 1.0 1 0 0 1 1 1 0 HOIP UBA domain pair ISG65-75 PF11727.8 EGD87662.2 - 0.047 12.9 1.7 0.05 12.8 1.7 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein WXG100 PF06013.12 EGD87662.2 - 0.049 13.9 1.4 0.057 13.7 1.4 1.1 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF4527 PF15030.6 EGD87662.2 - 0.086 12.3 0.2 0.086 12.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) XhlA PF10779.9 EGD87662.2 - 0.2 11.9 0.2 0.27 11.5 0.2 1.3 1 0 0 1 1 1 0 Haemolysin XhlA CsbD PF05532.12 EGD87662.2 - 1.7 8.6 11.6 20 5.2 11.6 2.4 1 1 0 1 1 1 0 CsbD-like Robl_LC7 PF03259.17 EGD87663.1 - 4.2e-05 23.2 0.3 0.39 10.5 0.0 3.2 3 0 0 3 3 3 3 Roadblock/LC7 domain SPX PF03105.19 EGD87663.1 - 2 8.2 7.5 2.3 8.1 7.5 1.0 1 0 0 1 1 1 0 SPX domain Ipi1_N PF12333.8 EGD87664.2 - 1.5e-22 80.1 0.5 2.1e-22 79.6 0.5 1.3 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation F-box PF00646.33 EGD87665.1 - 0.00013 21.7 0.2 0.00066 19.5 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EGD87665.1 - 0.056 13.3 0.4 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 F-box DUF1771 PF08590.10 EGD87668.1 - 2.8e-25 88.5 8.5 1e-24 86.6 5.5 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EGD87668.1 - 2.2e-10 40.7 0.4 2.2e-10 40.7 0.4 2.1 2 0 0 2 2 2 1 Smr domain Connexin43 PF03508.13 EGD87668.1 - 0.6 9.7 3.3 0.45 10.1 0.8 2.0 2 0 0 2 2 2 0 Gap junction alpha-1 protein (Cx43) DUF4407 PF14362.6 EGD87668.1 - 0.94 8.8 3.3 1.3 8.3 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) polyprenyl_synt PF00348.17 EGD87669.1 - 2.2e-67 226.8 0.0 2.9e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.19 EGD87670.1 - 3.6e-58 197.1 0.0 4.6e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RPE65 PF03055.15 EGD87671.2 - 2.9e-81 274.0 0.0 3.3e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Amino_oxidase PF01593.24 EGD87672.1 - 1.4e-29 103.7 0.0 1.9e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGD87672.1 - 5e-14 52.3 0.1 1.4e-13 50.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGD87672.1 - 4.2e-09 36.5 0.3 3.6e-08 33.4 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGD87672.1 - 3.3e-08 33.1 0.1 6.7e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGD87672.1 - 1.7e-06 27.0 0.5 0.0028 16.4 1.4 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 EGD87672.1 - 1.3e-05 24.7 3.2 0.00033 20.1 3.9 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGD87672.1 - 1.9e-05 23.9 2.8 9.8e-05 21.6 3.7 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EGD87672.1 - 0.0001 22.3 0.8 0.0097 15.9 0.3 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGD87672.1 - 0.001 18.4 1.5 0.0018 17.6 0.7 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGD87672.1 - 0.0028 16.9 0.9 0.0057 15.9 0.5 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EGD87672.1 - 0.0047 16.2 0.2 0.008 15.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 EGD87672.1 - 0.014 15.8 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GDI PF00996.18 EGD87672.1 - 0.025 13.1 0.1 0.094 11.2 0.0 1.8 2 0 0 2 2 2 0 GDP dissociation inhibitor Pyr_redox PF00070.27 EGD87672.1 - 0.041 14.4 3.3 1 10.0 1.8 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EGD87672.1 - 0.068 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 EGD87672.1 - 0.16 11.4 1.6 0.29 10.6 1.6 1.4 1 0 0 1 1 1 0 short chain dehydrogenase IlvN PF07991.12 EGD87672.1 - 0.18 11.4 0.5 0.44 10.1 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 EGD87672.1 - 0.21 10.6 2.4 0.25 10.3 1.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EGD87672.1 - 0.37 9.8 4.1 0.32 10.0 2.5 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A NB-ARC PF00931.22 EGD87673.1 - 0.00018 20.8 0.1 0.00018 20.8 0.1 1.0 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.15 EGD87673.1 - 0.03 14.2 0.1 0.031 14.2 0.1 1.2 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 EGD87673.1 - 0.065 13.5 0.0 0.077 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 EGD87673.1 - 0.073 12.6 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain DUF87 PF01935.17 EGD87673.1 - 0.18 11.9 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain Patatin PF01734.22 EGD87674.2 - 0.00016 22.0 0.4 0.072 13.3 0.0 2.2 1 1 0 2 2 2 2 Patatin-like phospholipase PilS PF08805.11 EGD87674.2 - 0.05 13.4 0.1 0.072 12.9 0.1 1.3 1 0 0 1 1 1 0 PilS N terminal BTB_2 PF02214.22 EGD87675.1 - 5.9e-07 29.8 0.1 1.1e-06 28.9 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EGD87675.1 - 2.5e-05 24.5 0.0 4.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain GNAT_like PF18407.1 EGD87675.1 - 0.19 12.1 0.0 0.65 10.4 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyltransferase like domain HLH PF00010.26 EGD87676.1 - 5.9e-12 45.4 1.2 1.1e-11 44.5 1.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DASH_Dad4 PF08650.10 EGD87676.1 - 0.052 13.5 0.5 0.16 11.9 0.5 1.9 1 1 0 1 1 1 0 DASH complex subunit Dad4 pP_pnuc_1 PF18165.1 EGD87676.1 - 0.81 9.6 4.1 7.8 6.4 4.1 2.2 1 1 0 1 1 1 0 Predicted pPIWI-associating nuclease Mobilization_B PF17511.2 EGD87676.1 - 1.3 9.4 7.6 0.1 13.0 0.9 2.1 1 1 1 2 2 2 0 Mobilization protein B SAC3_GANP PF03399.16 EGD87681.2 - 2.3e-105 352.2 4.5 2.3e-105 352.2 4.5 2.1 3 0 0 3 3 3 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EGD87681.2 - 1.7e-05 24.8 0.5 5.8e-05 23.1 0.5 1.9 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HC2 PF07382.11 EGD87681.2 - 1.1 9.3 22.6 2.3 8.3 22.6 1.4 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Zip PF02535.22 EGD87682.2 - 5.7e-52 177.0 2.4 7.2e-52 176.7 2.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ni_hydr_CYTB PF01292.20 EGD87682.2 - 2.2 7.8 13.5 0.021 14.4 3.6 2.4 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 CPP1-like PF11833.8 EGD87682.2 - 3.4 7.3 5.3 6.6 6.3 0.2 3.2 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2841 PF11001.8 EGD87683.1 - 1.6e-52 176.7 0.1 2.9e-52 175.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) CorA PF01544.18 EGD87683.1 - 0.056 12.8 0.2 0.083 12.2 0.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ABC_membrane PF00664.23 EGD87688.2 - 3e-86 289.5 31.4 9.2e-46 156.7 12.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGD87688.2 - 1.3e-48 165.0 0.0 2.6e-27 96.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGD87688.2 - 3.2e-10 39.8 0.1 0.00024 20.6 0.0 4.0 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGD87688.2 - 3.4e-06 27.1 1.7 0.037 14.1 0.1 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGD87688.2 - 4e-06 26.8 1.0 0.0018 18.2 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGD87688.2 - 0.00045 20.6 1.0 0.9 9.9 0.8 3.1 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 EGD87688.2 - 0.0022 18.1 0.7 0.2 11.7 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 EGD87688.2 - 0.0029 17.3 0.3 1.7 8.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGD87688.2 - 0.0048 17.4 0.3 0.34 11.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGD87688.2 - 0.0073 16.0 0.4 3.9 7.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 EGD87688.2 - 0.014 15.6 3.4 18 5.6 0.0 4.2 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 EGD87688.2 - 0.016 15.3 2.4 1.8 8.6 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 EGD87688.2 - 0.022 15.1 0.0 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EGD87688.2 - 0.023 15.0 1.9 3.8 7.8 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 EGD87688.2 - 0.04 13.7 0.8 0.66 9.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUP PF00674.18 EGD87688.2 - 0.057 13.6 0.7 0.37 10.9 0.7 2.5 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 EGD87688.2 - 0.07 13.0 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) bVLRF1 PF18826.1 EGD87689.1 - 2.7e-61 205.8 0.3 5.8e-61 204.7 0.3 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 EGD87689.1 - 0.0001 22.5 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGD87689.1 - 0.00087 19.6 0.1 0.0021 18.5 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EGD87689.1 - 0.0019 18.5 0.0 0.0055 17.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EGD87689.1 - 0.0056 17.2 0.0 0.014 16.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) P2X_receptor PF00864.19 EGD87690.1 - 0.027 13.6 0.1 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 ATP P2X receptor Pkinase PF00069.25 EGD87691.1 - 5.3e-57 193.2 0.1 6.7e-53 179.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87691.1 - 1.3e-26 93.5 0.0 4e-25 88.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGD87691.1 - 1.7e-10 41.1 0.1 4.9e-10 39.6 0.1 1.9 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 EGD87691.1 - 2e-06 26.9 0.8 5e-06 25.6 0.3 2.2 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGD87691.1 - 0.0025 17.2 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 EGD87691.1 - 0.0034 17.7 0.0 0.014 15.7 0.0 2.1 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 EGD87691.1 - 0.0094 15.9 0.0 0.024 14.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family TRAUB PF08164.12 EGD87691.1 - 0.048 14.2 1.2 0.13 12.8 1.2 1.7 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal Myb_DNA-bind_6 PF13921.6 EGD87693.2 - 0.0015 18.7 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGD87693.2 - 0.081 13.1 0.5 0.18 12.0 0.5 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3431 PF11913.8 EGD87695.1 - 3.9e-82 275.2 0.0 4.8e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) zf-CCCH PF00642.24 EGD87696.1 - 3.8e-08 33.0 2.9 6.8e-08 32.2 2.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 EGD87696.1 - 2.4e-07 30.5 6.8 5e-07 29.5 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD87696.1 - 4.5e-06 26.6 7.5 1.2e-05 25.3 7.5 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGD87696.1 - 5.5e-06 26.2 10.0 9.2e-06 25.5 10.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGD87696.1 - 9.6e-06 25.3 11.1 1.7e-05 24.6 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGD87696.1 - 1.5e-05 24.7 12.2 2.7e-05 23.9 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGD87696.1 - 3.1e-05 24.2 9.7 6e-05 23.3 9.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 EGD87696.1 - 7.7e-05 22.6 6.1 0.00014 21.8 6.1 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 EGD87696.1 - 0.00039 20.5 6.2 0.001 19.2 6.2 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 EGD87696.1 - 0.0024 17.6 3.0 0.0041 16.9 3.0 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 EGD87696.1 - 0.041 14.0 8.7 0.09 12.9 8.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Cript PF10235.9 EGD87696.1 - 0.063 13.8 0.7 0.26 11.9 0.7 2.1 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Prok-RING_4 PF14447.6 EGD87696.1 - 0.14 12.1 9.2 0.25 11.3 9.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF5427 PF10310.9 EGD87696.1 - 0.35 9.8 8.2 0.48 9.3 8.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) zf-rbx1 PF12678.7 EGD87696.1 - 3.8 7.9 8.5 11 6.5 8.5 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-CCCH_2 PF14608.6 EGD87696.1 - 4.3 8.0 7.2 0.42 11.2 2.6 1.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Mcp5_PH PF12814.7 EGD87697.1 - 4.4e-44 149.5 0.2 1.1e-43 148.3 0.2 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EGD87697.1 - 8.8e-05 23.0 0.0 0.00021 21.7 0.0 1.6 1 0 0 1 1 1 1 PH domain Herpes_UL25 PF01499.16 EGD87697.1 - 4.5 5.7 16.3 0.056 12.0 4.7 2.7 2 1 1 3 3 3 0 Herpesvirus UL25 family Methyltransf_23 PF13489.6 EGD87698.1 - 7.1e-16 58.5 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD87698.1 - 3.7e-07 30.8 0.0 2.8e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD87698.1 - 1.2e-06 29.0 0.0 8.1e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD87698.1 - 3.9e-05 23.5 0.0 0.00041 20.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD87698.1 - 0.0014 19.3 0.0 0.021 15.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain DUF2439 PF10382.9 EGD87699.1 - 2.1e-25 88.9 0.0 3.5e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) BAR PF03114.18 EGD87701.1 - 4.7e-13 49.4 0.1 7e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EGD87701.1 - 1.9e-12 46.6 0.1 3.8e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGD87701.1 - 4.9e-12 45.5 0.1 9.6e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGD87701.1 - 4e-09 36.0 0.1 9.7e-09 34.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PIN_8 PF18476.1 EGD87701.1 - 0.1 12.4 0.1 0.1 12.4 0.1 1.8 3 0 0 3 3 3 0 PIN like domain U1snRNP70_N PF12220.8 EGD87701.1 - 3.7 8.2 9.4 4.7 7.9 1.3 2.8 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TSC21 PF15217.6 EGD87703.1 - 0.034 14.1 0.4 0.81 9.6 0.0 2.7 2 1 1 3 3 3 0 TSC21 family RTC PF01137.21 EGD87709.1 - 1.7e-44 151.7 0.0 2.4e-43 147.9 0.0 2.0 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase DUF2786 PF10979.8 EGD87710.1 - 3e-15 55.8 0.5 3e-15 55.8 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) FlaF PF07309.11 EGD87710.1 - 2.1 8.4 5.3 3.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Flagellar protein FlaF Exo_endo_phos PF03372.23 EGD87711.1 - 2.6e-05 23.9 0.0 5.2e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MIOX PF05153.15 EGD87713.2 - 1.3e-116 388.5 0.8 1.7e-116 388.1 0.8 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase DUF1796 PF08795.10 EGD87713.2 - 0.0031 17.5 0.3 0.0055 16.7 0.3 1.4 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) HD PF01966.22 EGD87713.2 - 0.075 13.3 0.7 1 9.6 0.0 2.6 3 0 0 3 3 3 0 HD domain UBD PF16455.5 EGD87713.2 - 0.098 12.9 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-binding domain HNH_2 PF13391.6 EGD87714.1 - 2.3e-13 50.0 0.0 5.2e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Abhydrolase_1 PF00561.20 EGD87715.1 - 7.4e-48 163.4 0.0 2.6e-47 161.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD87715.1 - 0.00074 20.2 4.8 0.0019 18.9 4.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Gly_transf_sug PF04488.15 EGD87717.1 - 1e-17 64.6 0.1 2.6e-17 63.2 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EGD87717.1 - 0.013 14.9 0.1 0.041 13.3 0.0 1.7 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein MFS_1 PF07690.16 EGD87719.1 - 6.3e-34 117.4 29.9 7e-34 117.3 29.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Plasmodium_Vir PF05795.11 EGD87720.1 - 1.2 8.5 3.1 1.7 8.0 3.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SSP160 PF06933.11 EGD87720.1 - 9.3 4.3 24.0 14 3.7 24.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 THOC2_N PF16134.5 EGD87721.1 - 3.4e-241 802.3 0.0 7.1e-241 801.3 0.0 1.6 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EGD87721.1 - 2.4e-107 358.6 0.0 3.6e-107 358.0 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EGD87721.1 - 3.8e-30 103.8 0.3 1.1e-29 102.3 0.0 2.0 2 0 0 2 2 2 1 Transcription- and export-related complex subunit APH PF01636.23 EGD87722.1 - 1.4e-07 31.7 0.0 2.9e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD87722.1 - 0.0034 17.0 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase TniQ PF06527.11 EGD87722.1 - 0.051 14.3 0.1 0.088 13.5 0.1 1.3 1 0 0 1 1 1 0 TniQ GFA PF04828.14 EGD87724.1 - 1e-17 64.2 0.0 1e-17 64.2 0.0 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Vps5 PF09325.10 EGD87725.1 - 3e-11 43.4 2.3 6.5e-11 42.2 2.3 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EGD87725.1 - 1.2e-08 34.9 0.0 2.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 PX domain GTP_EFTU PF00009.27 EGD87726.1 - 5.8e-55 185.9 0.0 9.9e-55 185.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EGD87726.1 - 3.9e-25 87.7 0.0 9.1e-25 86.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EGD87726.1 - 1.6e-16 60.1 0.0 1e-08 35.0 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGD87726.1 - 4.4e-06 27.0 0.0 1.3e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGD87726.1 - 1.4e-05 25.0 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 EGD87726.1 - 0.061 13.1 0.1 16 5.3 0.0 2.6 1 1 1 2 2 2 0 Elongation factor G, domain IV RRM_1 PF00076.22 EGD87728.1 - 8.7e-29 99.2 0.1 1.1e-14 54.0 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGD87728.1 - 0.0021 17.7 0.0 0.35 10.5 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGD87728.1 - 0.0025 17.9 0.0 0.15 12.2 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif PHM7_cyt PF14703.6 EGD87728.1 - 0.056 13.7 0.1 8.9 6.5 0.1 2.8 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter API5 PF05918.11 EGD87728.1 - 1 8.1 5.1 1.5 7.5 5.1 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FRG2 PF15315.6 EGD87728.1 - 5.1 7.3 10.4 8.6 6.5 10.4 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 MARVEL PF01284.23 EGD87730.1 - 8.9e-07 29.0 4.7 1.4e-06 28.4 4.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF3245 PF11595.8 EGD87730.1 - 0.2 12.1 2.3 2.7 8.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) ATP-grasp_3 PF02655.14 EGD87732.1 - 3.5e-10 40.1 0.0 6.3e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GFO_IDH_MocA PF01408.22 EGD87733.1 - 1.6e-24 87.0 0.1 2.7e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGD87733.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EGD87733.1 - 3e-05 24.6 0.1 5.9e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 EGD87733.1 - 0.0018 18.4 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CBP_BcsQ PF06564.12 EGD87733.1 - 0.13 11.7 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ IF-2B PF01008.17 EGD87733.1 - 0.16 11.2 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family HPP PF04982.13 EGD87737.2 - 4.8e-16 59.0 0.3 6.3e-16 58.7 0.3 1.1 1 0 0 1 1 1 1 HPP family DUF3377 PF11857.8 EGD87737.2 - 0.028 14.3 0.3 0.063 13.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) MFS_1 PF07690.16 EGD87738.1 - 6.6e-37 127.2 53.5 9e-36 123.5 53.5 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD87738.1 - 1.1e-14 54.2 11.2 1.1e-14 54.2 11.2 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EGD87738.1 - 3.5e-14 52.2 15.9 5.2e-14 51.6 15.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3522 PF12036.8 EGD87738.1 - 0.83 9.9 6.4 0.094 13.0 1.0 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3522) DUF4267 PF14087.6 EGD87739.1 - 4.3e-24 84.7 2.1 5e-24 84.5 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) SLC3A2_N PF16028.5 EGD87740.1 - 0.0005 19.6 0.9 0.04 13.5 0.4 2.7 2 0 0 2 2 2 2 Solute carrier family 3 member 2 N-terminus ABC_tran PF00005.27 EGD87742.1 - 3.4e-48 163.6 0.0 1.5e-23 83.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGD87742.1 - 1.9e-21 75.9 3.2 1.9e-21 75.9 3.2 2.8 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 EGD87742.1 - 6.8e-19 68.8 1.5 0.001 19.0 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGD87742.1 - 2.1e-11 43.7 0.4 0.001 18.6 0.1 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGD87742.1 - 3.9e-08 32.9 1.3 0.0028 17.4 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGD87742.1 - 1.4e-07 32.2 5.5 0.029 14.9 0.2 3.9 4 0 0 4 4 4 2 AAA domain AAA_15 PF13175.6 EGD87742.1 - 4.4e-07 29.9 0.1 0.02 14.6 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 EGD87742.1 - 1.5e-06 28.2 0.0 0.011 15.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGD87742.1 - 2e-06 27.8 0.3 0.0067 16.4 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 EGD87742.1 - 3.5e-06 27.5 0.0 0.025 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EGD87742.1 - 4.1e-06 27.4 0.1 0.092 13.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 EGD87742.1 - 4.7e-05 23.7 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 EGD87742.1 - 4.9e-05 23.0 0.0 0.065 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EGD87742.1 - 0.00012 22.4 0.0 0.056 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGD87742.1 - 0.00017 21.6 0.2 0.49 10.3 0.1 2.6 2 0 0 2 2 2 2 NACHT domain Dynamin_N PF00350.23 EGD87742.1 - 0.00018 21.6 2.6 0.36 10.9 0.0 3.7 3 1 0 3 3 3 1 Dynamin family AAA PF00004.29 EGD87742.1 - 0.00022 21.7 0.0 1.1 9.7 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGD87742.1 - 0.00034 21.0 0.7 1.5 9.3 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_5 PF07728.14 EGD87742.1 - 0.00047 20.2 0.1 1.3 9.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGD87742.1 - 0.00064 19.9 2.0 0.31 11.2 0.1 3.3 4 0 0 4 4 3 1 AAA domain NB-ARC PF00931.22 EGD87742.1 - 0.00064 19.0 0.1 2.7 7.1 0.0 3.3 3 0 0 3 3 3 2 NB-ARC domain Roc PF08477.13 EGD87742.1 - 0.00099 19.3 0.1 3.3 7.9 0.0 3.2 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EGD87742.1 - 0.004 16.9 2.9 2.4 7.9 0.0 3.7 4 0 0 4 4 4 1 AAA domain DUF815 PF05673.13 EGD87742.1 - 0.0046 16.2 0.0 0.4 9.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EGD87742.1 - 0.0046 17.0 0.0 5.6 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF2813 PF11398.8 EGD87742.1 - 0.0056 16.0 0.6 0.99 8.6 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) Rad17 PF03215.15 EGD87742.1 - 0.0059 16.6 0.4 2.2 8.1 0.0 2.8 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_7 PF12775.7 EGD87742.1 - 0.012 15.1 0.9 2 7.9 0.0 3.0 3 0 0 3 3 3 0 P-loop containing dynein motor region MCM PF00493.23 EGD87742.1 - 0.016 14.3 0.1 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain NTPase_1 PF03266.15 EGD87742.1 - 0.018 14.9 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 NTPase GST_C_3 PF14497.6 EGD87742.1 - 0.033 14.4 0.2 0.08 13.1 0.2 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_25 PF13481.6 EGD87742.1 - 0.036 13.7 0.2 1.1 8.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 EGD87742.1 - 0.037 13.7 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 EGD87742.1 - 0.051 13.5 0.1 11 5.8 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 EGD87742.1 - 0.058 13.8 0.2 29 5.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain DAP3 PF10236.9 EGD87742.1 - 0.06 12.5 0.4 5.2 6.1 0.1 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Ras PF00071.22 EGD87742.1 - 0.063 12.9 0.0 6.9 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras family ABC_ATPase PF09818.9 EGD87742.1 - 0.084 11.6 0.3 20 3.8 0.0 3.3 3 1 0 3 3 3 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 EGD87742.1 - 0.092 12.5 0.0 2.8 7.6 0.0 2.9 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 EGD87742.1 - 0.095 12.4 1.9 3.4 7.3 0.1 3.2 3 1 0 3 3 3 0 AAA domain FeoB_N PF02421.18 EGD87742.1 - 0.12 11.9 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 EGD87742.1 - 0.12 12.1 2.4 3.8 7.3 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Cyclin_C_2 PF16899.5 EGD87743.1 - 4.3e-36 123.5 0.0 3.6e-32 110.9 0.0 2.4 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EGD87743.1 - 0.00031 20.5 0.0 0.00074 19.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain UQ_con PF00179.26 EGD87744.1 - 1.8e-43 147.6 0.0 2.2e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EGD87744.1 - 3.9e-06 26.6 0.0 8.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 EGD87744.1 - 5.6e-05 22.9 0.0 0.00011 21.9 0.0 1.4 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 EGD87744.1 - 0.06 13.6 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain AAA PF00004.29 EGD87746.1 - 8.2e-41 139.5 0.0 1.5e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD87746.1 - 1.2e-09 37.8 0.5 2.5e-09 36.8 0.5 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EGD87746.1 - 1.4e-09 37.7 0.1 2.7e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EGD87746.1 - 1.3e-05 25.4 0.0 2.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGD87746.1 - 2.3e-05 24.7 2.1 0.067 13.5 0.2 2.7 2 1 1 3 3 2 2 AAA domain DUF815 PF05673.13 EGD87746.1 - 5.3e-05 22.5 0.0 9.3e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EGD87746.1 - 9.9e-05 22.4 0.0 0.00028 20.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGD87746.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGD87746.1 - 0.0013 19.1 0.5 0.031 14.7 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 EGD87746.1 - 0.0024 18.2 0.4 0.0063 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGD87746.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 EGD87746.1 - 0.022 14.1 0.4 0.34 10.2 0.2 2.2 1 1 0 2 2 2 0 KaiC TIP49 PF06068.13 EGD87746.1 - 0.024 13.8 1.4 0.041 13.1 0.1 2.0 2 1 0 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 EGD87746.1 - 0.029 14.9 0.0 0.068 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGD87746.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGD87746.1 - 0.047 13.6 0.7 1.3 8.9 0.2 2.8 2 1 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 EGD87746.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGD87746.1 - 0.094 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGD87746.1 - 0.094 12.2 1.2 0.92 8.9 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 EGD87746.1 - 0.098 12.4 3.9 0.41 10.3 0.5 2.5 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGD87746.1 - 0.099 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 EGD87746.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EGD87746.1 - 0.13 12.6 0.4 0.36 11.1 0.4 1.7 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpb1_5 PF04998.17 EGD87746.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Mg_chelatase PF01078.21 EGD87746.1 - 0.14 11.5 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 EGD87746.1 - 0.15 11.7 0.7 0.83 9.3 0.0 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_30 PF13604.6 EGD87746.1 - 0.17 11.6 0.5 0.5 10.0 0.5 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGD87746.1 - 0.18 12.3 0.6 1.3 9.5 0.6 2.4 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EGD87746.1 - 0.18 11.0 0.1 0.18 11.0 0.1 1.9 3 0 0 3 3 2 0 Zeta toxin WD40 PF00400.32 EGD87747.1 - 1.9e-13 50.6 13.5 0.0013 19.5 0.2 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD87747.1 - 0.00076 19.7 0.0 2.6 8.4 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGD87747.1 - 0.18 11.6 0.0 2.4 8.0 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Mg_trans_NIPA PF05653.14 EGD87748.1 - 2.5e-63 213.9 14.2 8.1e-61 205.7 11.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EGD87748.1 - 0.00023 21.3 1.2 0.00023 21.3 1.2 3.8 3 1 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 EGD87748.1 - 0.0025 17.4 5.2 0.004 16.7 4.5 1.5 1 1 0 1 1 1 1 Solute carrier family 35 Trp_oprn_chp PF09534.10 EGD87748.1 - 0.0099 15.7 0.5 1.1 9.0 0.6 2.7 3 0 0 3 3 3 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ctr PF04145.15 EGD87748.1 - 0.098 13.3 0.1 24 5.5 0.0 3.2 2 2 0 2 2 2 0 Ctr copper transporter family DoxX_2 PF13564.6 EGD87748.1 - 0.31 11.2 8.2 1.7 8.8 0.9 2.8 2 1 1 3 3 3 0 DoxX-like family DUF2198 PF09964.9 EGD87748.1 - 0.48 10.5 5.9 0.14 12.3 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) bZIP_1 PF00170.21 EGD87749.1 - 1.9 8.6 11.1 4.8 7.3 6.0 2.7 2 0 0 2 2 2 0 bZIP transcription factor UPF0242 PF06785.11 EGD87749.1 - 6.4 6.8 11.1 3.6 7.6 0.5 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus VASt PF16016.5 EGD87750.1 - 2.2e-34 119.1 0.0 4.3e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EGD87750.1 - 3.8e-21 75.1 0.0 7e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 GRAM domain TPR_1 PF00515.28 EGD87751.1 - 4.1e-06 26.4 2.4 0.47 10.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGD87751.1 - 2e-05 24.3 5.8 0.011 15.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGD87751.1 - 0.00022 21.5 2.6 0.094 13.0 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGD87751.1 - 0.018 15.2 1.9 0.75 10.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGD87751.1 - 0.023 15.2 2.1 0.43 11.1 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGD87751.1 - 0.072 13.3 0.1 0.32 11.3 0.1 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGD87751.1 - 0.11 12.6 3.1 7.1 6.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGD87751.1 - 0.16 12.6 3.6 13 6.5 3.8 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGD87751.1 - 1.1 9.3 4.6 17 5.4 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Asp PF00026.23 EGD87752.2 - 2e-43 149.0 0.0 3.9e-28 98.8 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGD87752.2 - 0.0081 15.9 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EGD87752.2 - 0.043 14.5 0.2 3.7 8.2 0.0 2.8 2 1 0 2 2 2 0 Aspartyl protease TAXi_N PF14543.6 EGD87752.2 - 0.094 12.9 0.0 0.62 10.3 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EGD87752.2 - 0.16 12.6 0.0 2.6 8.7 0.0 2.6 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Cu_amine_oxid PF01179.20 EGD87753.1 - 5.7e-161 536.0 0.1 6.9e-161 535.7 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EGD87753.1 - 2.2e-18 66.5 0.1 5.1e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EGD87753.1 - 3.6e-14 52.8 0.0 7e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CAF1 PF04857.20 EGD87754.1 - 1.8e-24 86.5 0.0 3.3e-11 42.9 0.0 2.8 3 0 0 3 3 3 2 CAF1 family ribonuclease Siva PF05458.12 EGD87754.1 - 0.15 11.7 1.0 17 5.0 1.7 2.2 2 0 0 2 2 2 0 Cd27 binding protein (Siva) ANAPC_CDC26 PF10471.9 EGD87754.1 - 0.72 10.7 12.4 3.7 8.4 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 EGD87754.1 - 5.8 6.5 16.9 3.7 7.1 8.6 2.3 2 0 0 2 2 2 0 Spt20 family NDUF_B12 PF08122.12 EGD87755.1 - 9.8e-26 89.6 1.6 1.4e-25 89.1 1.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family WD40 PF00400.32 EGD87756.1 - 7e-19 67.8 9.0 0.0037 18.1 0.0 8.3 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD87756.1 - 8e-07 29.3 0.0 0.0011 19.2 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGD87756.1 - 0.069 12.1 0.2 0.73 8.7 0.1 2.5 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 EGD87756.1 - 0.16 11.2 0.0 0.34 10.1 0.0 1.6 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AMP-binding PF00501.28 EGD87757.1 - 2.8e-81 273.3 0.0 3.5e-81 273.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD87757.1 - 1.4e-14 54.8 0.3 3.5e-14 53.5 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NOA36 PF06524.12 EGD87759.2 - 0.049 13.0 12.5 0.048 13.0 12.5 1.0 1 0 0 1 1 1 0 NOA36 protein Rep_1 PF01446.17 EGD87759.2 - 0.091 12.2 0.7 0.1 12.1 0.7 1.0 1 0 0 1 1 1 0 Replication protein DUF5520 PF17658.1 EGD87759.2 - 0.1 11.7 2.1 0.12 11.5 2.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5520) Saw1 PF11561.8 EGD87759.2 - 0.13 11.7 0.2 0.12 11.9 0.2 1.0 1 0 0 1 1 1 0 Single strand annealing-weakened 1 DUF2457 PF10446.9 EGD87759.2 - 0.24 10.5 16.8 0.24 10.5 16.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Myc_N PF01056.18 EGD87759.2 - 0.31 10.9 7.1 0.31 10.9 7.1 1.0 1 0 0 1 1 1 0 Myc amino-terminal region SDA1 PF05285.12 EGD87759.2 - 0.45 9.9 11.4 0.48 9.8 11.4 1.0 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 EGD87759.2 - 0.7 10.0 12.8 0.64 10.1 12.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 EGD87759.2 - 1.1 9.0 14.4 1.1 9.0 14.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EGD87759.2 - 1.1 7.4 12.3 1.1 7.4 12.3 1.0 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 EGD87759.2 - 1.2 9.2 7.8 1.3 9.1 7.8 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 EGD87759.2 - 1.5 8.4 7.2 1.5 8.4 7.2 1.2 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 EGD87759.2 - 1.6 6.8 17.5 1.6 6.8 17.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 EGD87759.2 - 1.6 9.0 12.8 2.1 8.6 12.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TRAP_alpha PF03896.16 EGD87759.2 - 3.3 6.8 8.1 3.4 6.8 8.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.10 EGD87759.2 - 6 7.3 24.2 8.1 6.9 24.2 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 EGD87759.2 - 9.6 5.7 9.9 10 5.6 9.9 1.0 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CNH PF00780.22 EGD87760.2 - 2.1e-65 221.1 0.0 3.3e-65 220.5 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EGD87760.2 - 3.5e-34 118.6 1.8 7.8e-34 117.5 1.8 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EGD87760.2 - 2e-14 53.9 0.0 5.6e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGD87760.2 - 0.0019 18.7 0.0 0.0093 16.5 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 EGD87760.2 - 0.0026 17.6 0.1 2.2 8.1 0.0 2.6 2 0 0 2 2 2 2 PH domain PH_13 PF16652.5 EGD87760.2 - 0.13 12.0 0.4 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain RabGAP-TBC PF00566.18 EGD87761.1 - 8.9e-47 159.5 0.0 1.4e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EGD87761.1 - 1.1e-06 28.1 2.9 0.01 15.7 0.3 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGD87761.1 - 1.8e-05 23.9 1.0 0.1 12.2 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGD87761.1 - 0.00087 19.7 0.7 0.015 15.7 0.1 3.0 1 1 2 3 3 3 3 EF-hand domain pair GRAM PF02893.20 EGD87761.1 - 0.0021 17.9 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DUF4611 PF15387.6 EGD87761.1 - 2.3 8.5 10.3 3.2 8.0 1.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) CRPA PF05745.11 EGD87762.1 - 0.024 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) HMMR_N PF15905.5 EGD87763.1 - 0.00027 20.5 6.5 0.00027 20.5 6.5 2.3 2 1 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal Armet PF10208.9 EGD87763.1 - 0.056 13.4 0.4 0.12 12.4 0.4 1.4 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding HAUS5 PF14817.6 EGD87763.1 - 0.1 11.4 18.4 1 8.0 6.2 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 XkdW PF09636.10 EGD87763.1 - 0.1 12.7 3.4 0.38 10.9 0.1 3.0 3 0 0 3 3 2 0 XkdW protein DUF4201 PF13870.6 EGD87763.1 - 0.25 11.1 8.5 0.45 10.2 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) CREPT PF16566.5 EGD87763.1 - 0.35 11.0 13.2 0.18 12.0 2.7 2.7 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour bZIP_1 PF00170.21 EGD87763.1 - 0.64 10.2 5.1 18 5.5 0.5 3.5 2 1 1 3 3 3 0 bZIP transcription factor AAA_13 PF13166.6 EGD87763.1 - 1.1 7.8 10.9 2.2 6.8 10.9 1.5 1 0 0 1 1 1 0 AAA domain Filament PF00038.21 EGD87763.1 - 1.6 8.3 17.4 9.9 5.6 17.4 2.1 1 1 0 1 1 1 0 Intermediate filament protein DUF1319 PF07028.11 EGD87763.1 - 1.9 8.8 4.3 15 5.8 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) YabA PF06156.13 EGD87763.1 - 3.4 8.4 9.2 7.4 7.3 1.5 3.3 1 1 2 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 EGD87763.1 - 4.2 7.8 22.7 0.84 10.1 7.8 3.5 2 1 1 3 3 3 0 Fez1 DUF724 PF05266.14 EGD87763.1 - 5.5 6.8 11.3 6.4 6.6 2.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1640 PF07798.11 EGD87763.1 - 6.1 6.9 14.4 50 3.9 14.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Cnn_1N PF07989.11 EGD87763.1 - 6.1 7.1 8.0 3.9 7.7 0.5 3.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 EGD87763.1 - 7.4 5.4 18.4 1.2 7.9 8.0 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein adh_short_C2 PF13561.6 EGD87764.2 - 6.1e-35 120.9 2.5 2.6e-34 118.8 2.5 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD87764.2 - 3.7e-21 75.5 0.2 5.9e-21 74.8 0.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD87764.2 - 0.096 12.6 0.1 0.72 9.7 0.1 2.1 2 0 0 2 2 2 0 KR domain DUF1772 PF08592.11 EGD87765.1 - 0.00025 21.4 2.8 0.0022 18.3 2.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF1435 PF07256.12 EGD87765.1 - 0.043 13.9 0.1 0.081 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) DUF401 PF04165.12 EGD87765.1 - 0.19 11.0 1.6 0.24 10.7 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF401) SAP PF02037.27 EGD87766.1 - 3.1e-09 36.4 0.1 5.9e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 EGD87766.1 - 1.5e-07 31.6 0.0 1.5e-07 31.6 0.0 3.9 2 1 1 3 3 3 1 RNSP1-SAP18 binding (RSB) motif Pinin_SDK_memA PF04696.13 EGD87766.1 - 0.47 10.5 0.0 0.47 10.5 0.0 3.0 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region MitMem_reg PF13012.6 EGD87767.1 - 4.2e-12 46.5 2.3 1.4e-11 44.8 2.3 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGD87767.1 - 1.1e-10 41.5 0.0 2.5e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease KAsynt_C_assoc PF16197.5 EGD87767.1 - 0.0016 18.9 0.0 0.0041 17.6 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Proteasom_PSMB PF10508.9 EGD87768.1 - 0.044 12.3 0.2 2 6.8 0.0 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit RNA_pol_3_Rpc31 PF11705.8 EGD87769.1 - 6.1e-53 180.4 30.4 1.3e-31 110.6 0.1 2.0 1 1 1 2 2 2 2 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 EGD87769.1 - 0.0016 18.5 2.1 0.0017 18.5 2.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FAD_binding_1 PF00667.20 EGD87771.2 - 6e-30 104.5 0.0 7.9e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EGD87771.2 - 4.7e-13 49.7 0.0 8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGD87771.2 - 0.12 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain ETF PF01012.21 EGD87772.1 - 1.4e-40 139.2 0.4 1.7e-40 138.8 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ysc84 PF04366.12 EGD87773.1 - 1.5e-45 154.1 0.0 2.3e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Antimicrobial10 PF08105.11 EGD87773.1 - 0.021 14.9 0.2 0.97 9.6 0.2 2.5 2 0 0 2 2 2 0 Metchnikowin family Acetyltransf_3 PF13302.7 EGD87775.1 - 1.5e-09 38.6 0.0 2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGD87775.1 - 0.0029 17.8 0.0 0.049 13.9 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Peptidase_S10 PF00450.22 EGD87776.2 - 4.8e-66 223.9 1.6 9.7e-66 222.9 1.6 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase DUF4449 PF14613.6 EGD87776.2 - 0.017 15.2 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) Spem1 PF15670.5 EGD87777.2 - 0.039 13.5 4.2 0.043 13.4 4.2 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 RskA PF10099.9 EGD87777.2 - 0.1 12.9 0.3 0.12 12.7 0.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Miga PF10265.9 EGD87777.2 - 0.15 11.0 1.8 0.18 10.8 1.8 1.0 1 0 0 1 1 1 0 Mitoguardin GATase PF00117.28 EGD87778.1 - 7.5e-48 162.8 0.0 4.3e-47 160.3 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EGD87778.1 - 2.4e-44 150.3 0.0 1e-43 148.2 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 EGD87778.1 - 3.5e-05 23.7 0.3 0.0013 18.6 0.3 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EGD87778.1 - 0.039 13.8 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family RNA_pol_I_A49 PF06870.12 EGD87779.1 - 6e-69 232.8 0.2 7e-69 232.5 0.2 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Mucin15 PF15672.5 EGD87779.1 - 0.26 10.8 3.7 0.39 10.2 3.1 1.5 1 1 0 1 1 1 0 Cell-membrane associated Mucin15 Aminotran_1_2 PF00155.21 EGD87780.1 - 7.9e-86 288.5 0.0 1.3e-85 287.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGD87780.1 - 2.2e-06 26.5 0.0 4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGD87780.1 - 1.4e-05 24.6 0.1 2.7e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EGD87780.1 - 0.0012 17.9 0.0 0.0022 17.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGD87780.1 - 0.022 14.1 0.6 0.062 12.6 0.5 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase NitrOD2 PF18550.1 EGD87780.1 - 0.094 12.9 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Nitrososphaera output domain 2 p450 PF00067.22 EGD87781.2 - 1.6e-21 76.6 0.1 2e-21 76.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDI PF02234.19 EGD87781.2 - 0.01 16.0 0.3 0.022 14.9 0.3 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor p450 PF00067.22 EGD87782.2 - 6e-51 173.6 0.0 7.6e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Vps54 PF07928.12 EGD87783.1 - 8.3e-46 155.8 0.7 3.2e-45 153.9 0.7 2.1 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 EGD87783.1 - 5.3e-05 22.7 1.0 5.3e-05 22.7 1.0 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex SNF2_N PF00176.23 EGD87784.2 - 2.1e-70 237.2 0.6 2.1e-70 237.2 0.6 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 EGD87784.2 - 1.3e-25 89.3 0.4 1.5e-24 85.9 0.7 2.4 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.31 EGD87784.2 - 2.1e-19 69.9 0.3 6.4e-18 65.1 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 EGD87784.2 - 4.7e-19 68.5 11.0 4.7e-19 68.5 11.0 3.3 4 0 0 4 4 4 1 HSA QLQ PF08880.11 EGD87784.2 - 2.6e-13 49.4 4.8 2.6e-13 49.4 4.8 2.7 2 0 0 2 2 2 1 QLQ SnAC PF14619.6 EGD87784.2 - 2.7e-13 50.3 0.1 2.7e-13 50.3 0.1 3.7 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 EGD87784.2 - 2.4e-09 37.4 0.4 1.2e-08 35.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit BAR PF03114.18 EGD87785.1 - 7.4e-46 156.7 8.1 9e-46 156.4 8.1 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 EGD87785.1 - 4.8e-08 32.5 4.5 6.2e-08 32.1 4.5 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking TMPIT PF07851.13 EGD87785.1 - 5.3 6.2 6.3 8.8 5.5 6.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein Ada_Zn_binding PF02805.16 EGD87786.1 - 2.2e-29 101.3 4.3 4.1e-29 100.4 4.3 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 EGD87786.1 - 3.3e-07 30.2 0.0 7.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EGD87786.1 - 0.00038 20.7 0.0 0.00083 19.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Spt20 PF12090.8 EGD87786.1 - 0.062 12.9 10.9 0.13 11.8 10.9 1.5 1 0 0 1 1 1 0 Spt20 family Hydin_ADK PF17213.3 EGD87786.1 - 0.069 13.4 1.0 0.12 12.6 1.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF1840 PF08895.11 EGD87786.1 - 0.08 13.3 1.2 0.64 10.4 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) ANAPC_CDC26 PF10471.9 EGD87786.1 - 2.2 9.2 17.1 0.22 12.4 11.9 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF908 PF06012.12 EGD87786.1 - 4.9 6.5 12.6 8.3 5.7 12.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MAP65_ASE1 PF03999.12 EGD87786.1 - 5.3 5.6 8.8 7.3 5.2 8.8 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Ribosomal_L2_C PF03947.18 EGD87787.1 - 1.6e-41 141.4 5.9 2.8e-41 140.6 5.9 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGD87787.1 - 3.8e-13 49.2 0.1 9.6e-13 47.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.6 EGD87788.1 - 6.5e-07 28.7 0.0 1.6e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF1770 PF08589.10 EGD87789.2 - 8.8e-19 68.3 0.1 1.2e-18 67.8 0.1 1.4 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PfkB PF00294.24 EGD87790.1 - 5.6e-67 226.2 0.1 7e-67 225.9 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EGD87790.1 - 2e-05 24.1 0.0 3.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PS_pyruv_trans PF04230.13 EGD87790.1 - 0.0019 18.2 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase EST1_DNA_bind PF10373.9 EGD87791.1 - 1.1e-55 189.1 4.2 1.8e-55 188.4 4.2 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EGD87791.1 - 3.7e-23 82.7 0.9 1.3e-22 80.9 0.9 2.0 2 0 0 2 2 2 1 Telomerase activating protein Est1 Borrelia_lipo_1 PF05714.11 EGD87791.1 - 0.0079 16.0 0.5 0.015 15.0 0.5 1.4 1 0 0 1 1 1 1 Borrelia burgdorferi virulent strain associated lipoprotein Acyl-CoA_dh_1 PF00441.24 EGD87792.1 - 6.8e-32 110.8 2.7 7.4e-32 110.6 1.8 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGD87792.1 - 2.1e-19 69.5 0.0 3.7e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGD87792.1 - 6.2e-15 55.8 0.3 1.4e-14 54.7 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGD87792.1 - 1.5e-14 54.4 5.1 2.8e-14 53.5 5.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain IGPD PF00475.18 EGD87793.1 - 8.1e-58 194.8 1.3 1.2e-57 194.3 1.3 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Spo12 PF05032.12 EGD87794.1 - 3.1e-14 52.6 0.4 7e-14 51.4 0.4 1.6 1 0 0 1 1 1 1 Spo12 family Sad1_UNC PF07738.13 EGD87795.1 - 3.1e-31 108.1 0.0 5.9e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal KRAP_IP3R_bind PF14722.6 EGD87795.1 - 0.0096 15.7 0.8 0.035 13.8 0.8 1.9 1 0 0 1 1 1 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Pkinase PF00069.25 EGD87796.1 - 6.8e-47 160.0 0.0 1.1e-46 159.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87796.1 - 2.4e-30 105.7 0.0 3.9e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD87796.1 - 2.2e-07 30.5 0.0 4.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGD87796.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGD87796.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pep3_Vps18 PF05131.14 EGD87798.1 - 2.8e-45 153.8 0.0 7.9e-45 152.3 0.0 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EGD87798.1 - 8.6e-11 41.9 1.9 6.9e-06 26.0 0.0 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 EGD87798.1 - 0.00018 21.0 0.2 0.00037 20.0 0.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EGD87798.1 - 0.00095 19.0 1.0 0.0024 17.6 1.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGD87798.1 - 0.001 19.0 0.8 0.0024 17.8 0.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF2175 PF09943.9 EGD87798.1 - 0.0013 19.0 1.1 0.0098 16.2 0.1 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_11 PF17123.5 EGD87798.1 - 0.002 17.9 4.3 0.002 17.9 4.3 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 EGD87798.1 - 0.0047 17.2 0.8 0.012 15.9 0.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGD87798.1 - 0.038 14.0 0.8 0.098 12.7 0.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Vps39_2 PF10367.9 EGD87798.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.7 EGD87798.1 - 0.059 13.7 0.8 0.29 11.4 0.6 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGD87798.1 - 0.22 11.4 2.5 0.14 12.0 0.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SNF2_N PF00176.23 EGD87799.1 - 1.3e-64 218.2 2.6 1.3e-64 218.2 2.6 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain DBINO PF13892.6 EGD87799.1 - 3.5e-48 163.4 21.3 3.5e-48 163.4 21.3 5.8 6 1 1 7 7 7 1 DNA-binding domain Helicase_C PF00271.31 EGD87799.1 - 4.3e-19 68.9 0.0 1.3e-18 67.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD87799.1 - 1.4e-06 28.4 3.4 3.4e-06 27.2 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGD87799.1 - 0.00016 21.5 0.0 0.00053 19.8 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EGD87799.1 - 0.0044 16.2 3.3 0.018 14.2 0.0 3.2 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 baeRF_family12 PF18856.1 EGD87799.1 - 0.015 15.9 0.2 0.015 15.9 0.2 5.3 6 1 0 6 6 6 0 Bacterial archaeo-eukaryotic release factor family 12 Na_H_Exchanger PF00999.21 EGD87800.2 - 3.1e-68 230.3 31.8 3.6e-68 230.1 31.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TYA PF01021.19 EGD87800.2 - 0.058 13.7 0.7 0.11 12.9 0.7 1.3 1 0 0 1 1 1 0 TYA transposon protein Kelch_6 PF13964.6 EGD87800.2 - 0.14 12.5 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 Kelch motif DUF1673 PF07895.11 EGD87800.2 - 0.43 10.2 11.7 3.3 7.4 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) PepSY_TM PF03929.16 EGD87800.2 - 1.8 8.1 6.7 0.38 10.4 1.5 2.3 2 0 0 2 2 2 0 PepSY-associated TM region MFS_2 PF13347.6 EGD87802.1 - 7.9e-09 34.6 3.2 7.9e-09 34.6 3.2 1.8 2 0 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 EGD87802.1 - 0.00038 19.6 1.4 0.00075 18.6 1.4 1.4 1 0 0 1 1 1 1 PUCC protein STE PF02200.16 EGD87803.1 - 4.3e-20 72.2 0.9 1.1e-17 64.4 1.8 2.4 1 1 1 2 2 2 2 STE like transcription factor zf-C2H2 PF00096.26 EGD87803.1 - 2.1e-11 43.6 10.8 6.1e-07 29.5 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGD87803.1 - 2.1e-09 37.4 4.2 2.1e-09 37.4 4.2 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGD87803.1 - 1.1e-07 32.1 8.8 0.0009 19.9 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGD87803.1 - 0.0024 17.8 0.3 0.0024 17.8 0.3 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGD87803.1 - 0.0062 16.8 0.3 0.11 12.9 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.10 EGD87803.1 - 0.027 15.1 2.1 0.07 13.8 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_9 PF14369.6 EGD87803.1 - 0.058 13.7 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon zf-Di19 PF05605.12 EGD87803.1 - 0.069 13.5 0.3 0.069 13.5 0.3 2.4 2 1 0 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 EGD87803.1 - 0.13 12.5 0.4 0.29 11.4 0.4 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-TRAF PF02176.18 EGD87803.1 - 0.27 12.0 2.9 0.48 11.1 2.9 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger GAGA PF09237.11 EGD87803.1 - 1.6 8.6 5.3 0.76 9.6 1.5 2.3 2 0 0 2 2 2 0 GAGA factor zf-C2HC_2 PF13913.6 EGD87803.1 - 1.9 8.5 4.3 4.9 7.2 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 EGD87803.1 - 5.1 6.9 10.4 13 5.6 0.8 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain His_biosynth PF00977.21 EGD87806.1 - 5.6e-32 111.0 0.0 6.7e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EGD87806.1 - 0.076 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4064 PF13273.6 EGD87807.1 - 0.0022 18.2 0.7 0.0028 17.9 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF1345 PF07077.11 EGD87807.1 - 0.024 14.3 0.9 0.026 14.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) Pox_EPC_I2-L1 PF12575.8 EGD87807.1 - 0.065 13.5 0.9 1 9.7 0.5 2.0 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DUF3810 PF12725.7 EGD87807.1 - 0.11 11.8 0.6 0.12 11.7 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) LMBR1 PF04791.16 EGD87807.1 - 0.13 11.2 2.7 0.15 11.0 2.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4231 PF14015.6 EGD87807.1 - 0.15 12.5 1.3 0.2 12.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Insulin_TMD PF17870.1 EGD87807.1 - 0.16 12.1 1.2 13 6.0 0.7 2.3 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF2207 PF09972.9 EGD87807.1 - 0.4 9.4 1.7 0.46 9.2 1.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SNARE PF05739.19 EGD87807.1 - 2.3 8.3 5.7 1.1 9.3 2.8 2.0 3 0 0 3 3 3 0 SNARE domain Radical_SAM_C PF16199.5 EGD87808.1 - 3.3e-32 110.3 0.1 9.4e-32 108.9 0.0 1.8 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EGD87808.1 - 1.8e-19 70.7 0.1 7e-19 68.8 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EGD87808.1 - 3.2e-10 40.3 0.0 6.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGD87808.1 - 1.4e-06 28.3 0.2 1.3e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGD87808.1 - 0.087 13.3 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.19 EGD87809.1 - 5.3e-27 94.3 4.3 5.3e-27 94.3 1.8 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EGD87809.1 - 1.8e-22 79.8 0.3 3.2e-22 79.0 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EGD87809.1 - 2.6e-08 33.8 0.1 5.9e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EGD87809.1 - 1.3e-05 25.7 0.1 2.9e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain Ribosomal_L5_C PF00673.21 EGD87810.1 - 2.3e-28 98.2 0.0 4.5e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGD87810.1 - 4.7e-06 26.9 0.0 8.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Pkinase PF00069.25 EGD87811.2 - 2.4e-69 233.6 0.0 9.6e-69 231.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87811.2 - 1.9e-47 161.7 0.0 4.1e-47 160.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EGD87811.2 - 3.9e-28 97.7 0.0 7.5e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 EGD87811.2 - 5.2e-08 32.5 0.0 0.00025 20.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_1 PF00536.30 EGD87811.2 - 5.2e-06 26.8 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EGD87811.2 - 7.9e-05 23.2 0.0 0.00015 22.3 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 EGD87811.2 - 0.0025 16.7 0.9 0.0044 15.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase SAM_2 PF07647.17 EGD87811.2 - 0.0082 16.2 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 EGD87811.2 - 0.03 14.3 0.2 0.067 13.2 0.2 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Kdo PF06293.14 EGD87811.2 - 0.072 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGD87811.2 - 0.18 10.8 0.1 0.84 8.6 0.0 2.1 3 0 0 3 3 3 0 Seadornavirus VP7 MSA-2c PF12238.8 EGD87811.2 - 0.46 10.5 3.9 1 9.3 0.0 2.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Fungal_trans PF04082.18 EGD87812.2 - 1e-13 50.9 0.3 1e-13 50.9 0.3 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EGD87812.2 - 1.6e-08 34.5 5.9 1.9e-08 34.4 3.0 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGD87812.2 - 3.7e-08 33.4 4.3 2.9e-05 24.3 0.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD87812.2 - 3.5e-05 24.3 4.0 0.0033 18.1 0.4 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGD87812.2 - 0.078 13.3 0.8 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding BolA PF01722.18 EGD87812.2 - 0.16 12.3 0.2 0.58 10.5 0.2 1.9 1 0 0 1 1 1 0 BolA-like protein zf-C2H2_4 PF13894.6 EGD87813.2 - 0.0045 17.7 8.2 0.15 13.0 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGD87813.2 - 0.0054 17.1 12.7 0.017 15.6 0.4 3.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EGD87813.2 - 0.048 13.4 1.9 0.066 13.0 0.1 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type MMR_HSR1 PF01926.23 EGD87814.1 - 2e-16 60.1 0.4 2.2e-14 53.5 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGD87814.1 - 1.9e-06 27.5 0.6 3.2e-05 23.5 0.2 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGD87814.1 - 0.0001 22.2 0.1 0.022 14.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EGD87814.1 - 0.0018 17.6 0.1 0.0037 16.6 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Ribosomal_60s PF00428.19 EGD87814.1 - 0.19 12.4 10.6 0.61 10.7 10.6 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein Dynamin_N PF00350.23 EGD87814.1 - 0.49 10.4 7.0 0.31 11.1 0.5 3.2 3 1 1 4 4 4 0 Dynamin family LTV PF04180.14 EGD87815.2 - 4.1e-82 276.9 11.2 4.7e-82 276.8 11.2 1.0 1 0 0 1 1 1 1 Low temperature viability protein PLDc_2 PF13091.6 EGD87816.2 - 2.2e-09 37.3 0.1 0.0003 20.7 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGD87816.2 - 3.3e-09 36.6 2.7 0.0017 18.5 0.4 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif NDUFA12 PF05071.16 EGD87817.1 - 6.9e-33 113.4 3.7 8.5e-33 113.1 3.7 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TPR_2 PF07719.17 EGD87818.2 - 7.9e-09 35.0 1.0 0.049 13.8 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGD87818.2 - 8.7e-09 35.5 9.5 0.016 16.0 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGD87818.2 - 6.1e-08 33.1 8.8 0.02 15.4 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGD87818.2 - 9.4e-07 28.6 5.1 0.053 13.8 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGD87818.2 - 6.5e-05 22.6 2.9 0.015 15.1 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGD87818.2 - 9.1e-05 22.6 0.0 3.8 8.1 0.0 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGD87818.2 - 0.0012 19.4 7.3 2.7 8.7 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGD87818.2 - 0.14 12.5 2.8 11 6.4 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGD87818.2 - 0.21 10.7 2.0 5 6.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGD87818.2 - 0.69 10.3 3.8 8.3 6.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_25 PF13649.6 EGD87819.1 - 2.3e-32 111.6 0.0 5.2e-16 59.1 0.0 3.2 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGD87819.1 - 6.1e-31 106.9 0.0 1.1e-15 58.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EGD87819.1 - 1.7e-22 79.8 0.0 4.1e-11 42.9 0.0 3.3 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 EGD87819.1 - 2.7e-20 72.9 0.0 7.8e-11 42.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGD87819.1 - 5e-15 56.0 0.0 7.7e-08 33.0 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain MetW PF07021.12 EGD87819.1 - 2e-11 43.9 0.0 7.3e-06 25.7 0.0 2.7 3 0 0 3 3 3 2 Methionine biosynthesis protein MetW CMAS PF02353.20 EGD87819.1 - 8.2e-11 41.7 0.0 5.1e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGD87819.1 - 9.4e-11 41.5 0.0 1.3e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family NodS PF05401.11 EGD87819.1 - 1.1e-07 31.7 0.0 0.00016 21.3 0.0 2.2 2 0 0 2 2 2 2 Nodulation protein S (NodS) MTS PF05175.14 EGD87819.1 - 2.6e-07 30.4 0.0 0.0013 18.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain DREV PF05219.12 EGD87819.1 - 1e-06 28.0 0.0 0.013 14.7 0.0 2.4 2 0 0 2 2 2 2 DREV methyltransferase GidB PF02527.15 EGD87819.1 - 4.7e-06 26.0 0.0 0.0022 17.3 0.0 2.3 2 0 0 2 2 2 2 rRNA small subunit methyltransferase G PrmA PF06325.13 EGD87819.1 - 5.8e-05 22.6 0.0 0.33 10.3 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EGD87819.1 - 7.1e-05 22.8 0.0 0.0036 17.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGD87819.1 - 0.00024 21.1 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EGD87819.1 - 0.00025 20.3 0.0 0.014 14.6 0.0 2.9 4 0 0 4 4 4 1 NNMT/PNMT/TEMT family RrnaAD PF00398.20 EGD87819.1 - 0.00054 19.1 0.0 0.94 8.5 0.0 2.3 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase TehB PF03848.14 EGD87819.1 - 0.00076 18.9 0.0 0.0036 16.8 0.0 1.9 2 0 0 2 2 2 1 Tellurite resistance protein TehB PCMT PF01135.19 EGD87819.1 - 0.00092 19.0 0.0 1.1 9.0 0.0 3.0 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EGD87819.1 - 0.0025 17.3 0.1 2.4 7.6 0.0 3.3 3 0 0 3 3 3 1 Putative methyltransferase CheR PF01739.18 EGD87819.1 - 0.0035 16.8 0.0 0.71 9.3 0.0 3.2 3 0 0 3 3 3 1 CheR methyltransferase, SAM binding domain Met_10 PF02475.16 EGD87819.1 - 0.0053 16.5 0.0 0.013 15.2 0.0 1.8 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 EGD87819.1 - 0.0075 15.9 0.1 0.4 10.3 0.0 2.3 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Pox_MCEL PF03291.16 EGD87819.1 - 0.0076 15.4 0.0 0.16 11.1 0.0 2.4 2 1 1 3 3 3 1 mRNA capping enzyme FtsJ PF01728.19 EGD87819.1 - 0.0081 16.3 0.0 0.086 12.9 0.0 2.3 2 1 1 3 3 3 1 FtsJ-like methyltransferase Spermine_synth PF01564.17 EGD87819.1 - 0.012 15.0 0.0 0.07 12.5 0.0 2.1 2 0 0 2 2 2 0 Spermine/spermidine synthase domain TetR_N PF00440.23 EGD87819.1 - 0.036 13.9 0.0 0.099 12.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family SIS_2 PF13580.6 EGD87819.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 SIS domain Methyltransf_9 PF08003.11 EGD87819.1 - 0.16 10.8 0.0 0.58 9.0 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) p450 PF00067.22 EGD87821.2 - 2.6e-35 122.1 0.0 3.6e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RIX1 PF08167.12 EGD87822.1 - 5e-58 196.0 2.1 1.1e-57 194.9 2.1 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis MBOAT_2 PF13813.6 EGD87823.1 - 3.4e-21 75.3 1.3 7.7e-21 74.2 1.3 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SNF2_N PF00176.23 EGD87824.2 - 1.3e-66 224.7 0.0 2.3e-66 223.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGD87824.2 - 3.5e-06 26.9 0.0 1.5e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Slu7 PF11708.8 EGD87824.2 - 0.17 11.6 1.0 0.26 11.0 1.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor SNF2_N PF00176.23 EGD87825.2 - 1.1e-47 162.5 0.9 1.8e-47 161.8 0.2 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGD87825.2 - 1.3e-17 64.1 0.0 4e-17 62.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD87825.2 - 3.7e-07 30.3 0.4 1.2e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGD87825.2 - 2.1e-05 23.9 0.0 4.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 EGD87825.2 - 5e-05 23.1 0.0 0.013 15.2 0.0 2.6 2 0 0 2 2 2 2 SWI2/SNF2 ATPase SAM_1 PF00536.30 EGD87825.2 - 0.026 15.0 0.0 0.084 13.3 0.0 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGD87825.2 - 0.047 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) GSH_synth_ATP PF03917.17 EGD87826.1 - 1.8e-132 441.7 0.0 2.1e-132 441.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EGD87826.1 - 1e-27 96.6 0.0 2.2e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Bestrophin PF01062.21 EGD87830.1 - 1.1e-35 123.4 0.0 1.7e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Aminotran_3 PF00202.21 EGD87832.1 - 1.4e-125 419.1 0.0 1.6e-125 418.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGD87832.1 - 0.0094 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Spt4 PF06093.13 EGD87833.2 - 2.6e-32 110.7 0.2 3.1e-32 110.5 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.11 EGD87833.2 - 0.059 13.4 0.2 0.095 12.7 0.2 1.4 1 1 0 1 1 1 0 Coronavirus gene 5 protein PPP5 PF08321.12 EGD87834.1 - 1.8e-34 117.9 0.3 4.3e-34 116.7 0.3 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 EGD87834.1 - 3.4e-31 109.3 0.0 4.9e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 EGD87834.1 - 7.8e-12 44.5 4.2 0.00012 21.8 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGD87834.1 - 4.2e-11 42.3 2.9 2.8e-06 26.9 0.1 3.3 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.17 EGD87834.1 - 1.4e-09 37.4 4.0 0.0048 16.9 0.5 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGD87834.1 - 3.8e-06 27.5 3.1 0.16 12.6 0.1 3.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGD87834.1 - 1.5e-05 25.1 0.1 0.019 15.1 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGD87834.1 - 0.00083 19.8 0.8 0.47 11.0 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGD87834.1 - 0.0024 18.1 0.8 5.2 7.7 0.0 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGD87834.1 - 0.0028 18.2 1.1 3.6 8.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGD87834.1 - 0.0029 17.9 0.2 0.015 15.5 0.2 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGD87834.1 - 0.014 16.2 0.9 10 7.2 0.1 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGD87834.1 - 0.043 14.0 1.1 0.28 11.5 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGD87834.1 - 0.15 12.1 0.2 1.9 8.7 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EGD87834.1 - 0.37 10.9 5.6 0.93 9.6 0.1 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF89 PF01937.19 EGD87835.1 - 3.2e-136 453.9 0.1 3.6e-136 453.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 FlxA PF14282.6 EGD87835.1 - 0.0037 17.2 0.6 3.3 7.7 0.2 2.6 3 0 0 3 3 3 2 FlxA-like protein Cut12 PF11500.8 EGD87836.1 - 3.9e-47 159.8 13.9 3.9e-47 159.8 13.9 4.1 2 1 0 3 3 3 1 Spindle pole body formation-associated protein ACP PF06857.11 EGD87836.1 - 0.23 11.7 1.1 1.2 9.4 0.3 2.5 2 0 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) DUF2730 PF10805.8 EGD87836.1 - 2.3 8.4 7.7 0.55 10.4 0.3 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Pkinase PF00069.25 EGD87837.2 - 8.8e-66 222.0 0.0 2.2e-32 112.5 0.0 3.5 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 EGD87837.2 - 2.6e-48 164.8 0.2 2.6e-48 164.8 0.2 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 EGD87837.2 - 1.2e-33 116.5 0.0 7.4e-16 58.2 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EGD87837.2 - 2.1e-18 66.7 2.1 4.5e-18 65.6 0.6 2.4 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 EGD87837.2 - 4.1e-12 46.0 1.1 3e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 EGD87837.2 - 0.0022 17.4 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGD87837.2 - 0.0045 16.9 0.1 0.0045 16.9 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGD87837.2 - 0.077 12.6 0.0 0.8 9.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGD87837.2 - 0.9 8.2 4.1 0.41 9.4 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Torus PF16131.5 EGD87838.1 - 3.5e-45 153.2 2.5 4.6e-45 152.8 0.0 2.4 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 EGD87838.1 - 2.1e-08 33.8 0.0 4.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EGD87838.1 - 0.00026 20.9 1.0 0.00047 20.1 1.0 1.4 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 EGD87838.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ifi-6-16 PF06140.13 EGD87838.1 - 0.018 14.9 0.9 0.032 14.1 0.9 1.3 1 0 0 1 1 1 0 Interferon-induced 6-16 family zf-CCCH PF00642.24 EGD87838.1 - 0.026 14.4 1.7 0.047 13.6 1.7 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGD87838.1 - 1.2 9.1 3.8 1.9 8.4 3.8 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger MMR_HSR1 PF01926.23 EGD87839.2 - 1.7e-20 73.2 0.6 2.6e-20 72.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EGD87839.2 - 9.1e-18 64.2 0.5 1.1e-16 60.8 0.1 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EGD87839.2 - 5.3e-17 61.6 0.1 1.4e-16 60.3 0.0 1.7 1 1 1 2 2 2 1 TGS domain FeoB_N PF02421.18 EGD87839.2 - 8.8e-13 48.1 0.0 1.2e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGD87839.2 - 2.3e-05 24.5 0.3 0.026 14.6 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 EGD87839.2 - 0.034 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MeaB PF03308.16 EGD87839.2 - 0.078 12.0 0.1 0.14 11.1 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 EGD87839.2 - 0.079 12.0 0.1 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain DnaJ_C PF01556.18 EGD87840.1 - 4.7e-36 124.1 0.5 6.2e-36 123.7 0.5 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGD87840.1 - 2.7e-28 97.9 1.7 4.8e-28 97.1 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain PIG-X PF08320.12 EGD87841.1 - 1.1e-70 237.9 0.1 1.7e-70 237.3 0.1 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 RFX_DNA_binding PF02257.15 EGD87842.1 - 6.2e-27 94.0 0.1 1.5e-26 92.8 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.19 EGD87843.1 - 9.6e-27 92.7 9.0 9.6e-27 92.7 9.0 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Peroxin-3 PF04882.12 EGD87845.1 - 6.8e-167 556.2 0.1 8e-167 556.0 0.1 1.0 1 0 0 1 1 1 1 Peroxin-3 Na_H_Exchanger PF00999.21 EGD87846.2 - 1.2e-19 70.4 9.3 1.5e-19 70.1 9.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PUMA PF15826.5 EGD87846.2 - 0.65 10.2 4.9 1.2 9.3 4.9 1.4 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis MFS_1 PF07690.16 EGD87847.1 - 2.4e-36 125.4 28.5 2.4e-36 125.4 28.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Cytochrom_B561 PF03188.16 EGD87847.1 - 0.064 13.4 2.8 0.35 11.0 0.2 2.8 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 zf-C4H2 PF10146.9 EGD87848.1 - 0.013 15.8 6.8 0.032 14.5 6.8 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein PRIMA1 PF16101.5 EGD87848.1 - 0.015 15.4 4.2 0.038 14.0 4.2 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SRP-alpha_N PF04086.13 EGD87848.1 - 3.4 7.5 13.6 0.23 11.3 4.9 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal ThiF PF00899.21 EGD87849.1 - 3.8e-32 111.6 0.0 4.7e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 ThiF family Ytp1 PF10355.9 EGD87850.2 - 3.7e-57 193.7 15.7 3.7e-57 193.7 15.7 2.4 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EGD87850.2 - 1e-31 108.8 3.2 1e-31 108.8 3.2 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF3180 PF11377.8 EGD87850.2 - 0.027 14.6 8.3 0.47 10.6 5.1 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF3180) ExoD PF06055.12 EGD87850.2 - 0.038 13.4 0.0 0.038 13.4 0.0 2.8 3 0 0 3 3 3 0 Exopolysaccharide synthesis, ExoD DUF973 PF06157.11 EGD87850.2 - 0.12 11.5 9.1 0.22 10.6 9.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF4225 PF13988.6 EGD87850.2 - 2.3 7.7 4.3 4.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Swi5 PF07061.11 EGD87851.1 - 5.7e-28 96.8 0.1 7.6e-28 96.4 0.1 1.2 1 0 0 1 1 1 1 Swi5 ABC_tran_CTD PF16326.5 EGD87851.1 - 0.016 15.5 0.3 0.027 14.7 0.3 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain Kre28 PF17097.5 EGD87851.1 - 0.054 12.4 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Spindle pole body component DUF4041 PF13250.6 EGD87851.1 - 0.078 12.9 0.2 0.33 10.9 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4041) DUF641 PF04859.12 EGD87851.1 - 0.16 12.3 0.0 0.21 11.9 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Striatin PF08232.12 EGD87852.1 - 0.012 16.2 3.7 0.012 16.2 3.7 2.5 2 1 0 2 2 2 0 Striatin family SKA1 PF07160.12 EGD87852.1 - 0.015 15.1 4.3 0.039 13.8 4.3 1.7 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Pox_A_type_inc PF04508.12 EGD87852.1 - 0.036 13.9 3.4 0.56 10.2 0.5 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat HOOK PF05622.12 EGD87852.1 - 0.041 12.0 10.9 3.2 5.8 0.0 2.1 2 0 0 2 2 2 0 HOOK protein ASXH PF13919.6 EGD87852.1 - 0.063 13.3 5.7 0.55 10.3 5.7 2.5 1 1 0 1 1 1 0 Asx homology domain Exonuc_VII_L PF02601.15 EGD87852.1 - 0.17 11.4 6.0 0.4 10.2 6.0 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cauli_AT PF03233.13 EGD87852.1 - 0.4 10.6 4.2 0.42 10.5 1.4 2.2 2 0 0 2 2 2 0 Aphid transmission protein CENP-Q PF13094.6 EGD87852.1 - 0.54 10.4 17.7 0.34 11.1 12.0 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.19 EGD87852.1 - 2.1 6.2 6.6 3.1 5.6 6.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 EGD87852.1 - 7.4 5.3 6.2 13 4.5 6.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2570 PF10828.8 EGD87852.1 - 9.4 6.1 11.4 23 4.9 10.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) Glycos_transf_2 PF00535.26 EGD87853.1 - 3.3e-23 82.3 0.0 3.9e-21 75.6 0.0 2.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGD87853.1 - 9.6e-05 22.4 0.0 0.32 10.9 0.0 3.0 2 1 0 3 3 3 2 Glycosyltransferase like family 2 Dicty_CAR PF05462.11 EGD87854.1 - 1e-09 38.0 9.7 1e-09 38.0 9.7 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 EGD87854.1 - 4.8e-07 29.3 10.6 1.8e-06 27.4 10.1 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 EGD87854.1 - 6.6e-05 22.8 8.7 0.00014 21.7 8.7 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 EGD87854.1 - 0.00081 18.5 15.2 0.16 11.0 15.2 2.3 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7TM_GPCR_Srsx PF10320.9 EGD87854.1 - 0.0088 15.5 4.1 0.014 14.8 4.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx GPR_Gpa2_C PF11970.8 EGD87854.1 - 0.088 12.9 0.4 0.088 12.9 0.4 2.3 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF1174 PF06671.11 EGD87854.1 - 4.6 7.0 8.3 9.2 6.1 8.3 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1174) Fez1 PF06818.15 EGD87855.1 - 0.016 15.7 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 Fez1 DUF3614 PF12267.8 EGD87855.1 - 0.16 12.5 0.1 0.36 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Kdo PF06293.14 EGD87856.1 - 0.0013 18.1 0.1 0.0024 17.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGD87856.1 - 0.0045 16.9 0.1 0.0045 16.9 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD87856.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Autophagy_N PF03986.13 EGD87857.1 - 5.3e-45 152.7 0.4 1.1e-44 151.8 0.0 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EGD87857.1 - 4.5e-14 52.8 0.1 8e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain TFIIB PF00382.19 EGD87858.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 2 0 Transcription factor TFIIB repeat EST1_DNA_bind PF10373.9 EGD87860.1 - 7.2e-12 45.4 1.5 8.4e-10 38.6 0.6 2.5 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain zf-C3HC4_3 PF13920.6 EGD87862.1 - 7.1e-11 41.8 6.5 1.4e-10 40.9 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGD87862.1 - 3.4e-06 26.8 2.8 9.1e-06 25.4 2.8 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGD87862.1 - 5.6e-05 22.9 5.6 9.7e-05 22.2 3.8 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGD87862.1 - 0.00013 22.2 6.6 0.00026 21.3 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGD87862.1 - 0.0042 17.0 4.8 0.0072 16.3 4.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGD87862.1 - 0.015 15.2 4.3 0.015 15.2 4.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGD87862.1 - 0.28 11.4 3.6 2.2 8.5 4.0 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING YacG PF03884.14 EGD87862.1 - 2 8.2 4.5 4.4 7.1 2.2 2.4 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG CDC45 PF02724.14 EGD87862.1 - 2.5 6.3 4.6 3.5 5.8 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein NUDIX PF00293.28 EGD87864.2 - 3.6e-09 36.8 0.0 6.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 EGD87865.1 - 1.9e-14 53.8 0.0 4.1e-14 52.8 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain HAD_2 PF13419.6 EGD87866.1 - 3.8e-19 69.5 0.0 5e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 EGD87866.1 - 1.8e-06 27.8 0.0 4.2e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 EGD87866.1 - 2.2e-05 24.9 0.1 0.00015 22.1 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGD87866.1 - 0.0016 18.5 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4853 PF16145.5 EGD87866.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) Rit1_C PF17184.4 EGD87867.1 - 8.4e-98 327.1 0.0 1.1e-97 326.7 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EGD87867.1 - 7e-35 119.7 0.0 1.4e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Aldo_ket_red PF00248.21 EGD87868.1 - 3.2e-28 98.8 0.0 7.8e-26 90.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Tannase PF07519.11 EGD87870.2 - 5e-99 332.3 0.1 5.8e-99 332.1 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EGD87870.2 - 6.9e-07 29.0 0.0 0.035 13.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGD87870.2 - 0.031 13.5 0.0 0.46 9.7 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Zn_clus PF00172.18 EGD87871.1 - 3.3e-08 33.5 13.2 5.7e-08 32.7 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpc82 PF05645.13 EGD87873.2 - 3e-39 135.4 0.0 5.2e-35 121.4 0.0 2.6 2 1 1 3 3 3 3 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EGD87873.2 - 2.4e-11 43.5 3.2 0.00028 20.9 0.2 3.8 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EGD87873.2 - 4.8e-07 29.6 0.1 4.1e-06 26.6 0.1 2.5 2 1 0 3 3 3 1 TFIIE alpha subunit FAM176 PF14851.6 EGD87873.2 - 0.27 10.9 6.9 2.5 7.8 0.5 3.5 3 0 0 3 3 3 0 FAM176 family PBP1_TM PF14812.6 EGD87873.2 - 1.2 9.6 7.6 2.3 8.7 0.8 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 EGD87873.2 - 2.3 8.7 10.3 0.16 12.3 0.3 2.8 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Peptidase_M16 PF00675.20 EGD87874.2 - 5.3e-17 62.2 0.0 9.9e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGD87874.2 - 4.8e-12 46.3 0.0 8.7e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Mito_carr PF00153.27 EGD87875.1 - 1.6e-25 88.8 6.8 7.4e-12 45.0 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Doppel PF11466.8 EGD87878.2 - 0.53 10.0 3.8 3.4 7.4 2.1 2.4 2 0 0 2 2 2 0 Prion-like protein Doppel Citrate_synt PF00285.21 EGD87879.1 - 2.6e-100 336.0 0.0 3.4e-100 335.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 EGD87879.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Eclosion hormone DSPc PF00782.20 EGD87880.2 - 5.4e-19 68.3 0.0 4.9e-16 58.7 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGD87880.2 - 0.077 12.5 2.5 0.28 10.7 0.1 2.1 1 1 1 2 2 2 0 Protein-tyrosine phosphatase CTD_bind PF04818.13 EGD87882.2 - 1.5e-08 35.3 0.0 3.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 EGD87882.2 - 3.2e-07 30.1 0.0 5.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GET2 PF08690.10 EGD87882.2 - 1.2 8.7 4.5 2.3 7.8 4.5 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 TFIIA PF03153.13 EGD87882.2 - 2.2 8.2 16.9 3.3 7.6 16.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit E1-E2_ATPase PF00122.20 EGD87884.2 - 6.5e-48 162.6 5.0 6.5e-48 162.6 5.0 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGD87884.2 - 1.9e-17 64.2 0.0 5.6e-17 62.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGD87884.2 - 2.4e-11 43.1 0.0 5.3e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGD87884.2 - 0.0017 18.4 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGD87884.2 - 0.0053 16.5 0.1 0.0053 16.5 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 EGD87884.2 - 0.1 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) O-antigen_lig PF13425.6 EGD87884.2 - 0.1 11.3 5.3 0.3 9.8 5.3 1.7 1 0 0 1 1 1 0 O-antigen ligase like membrane protein GET2 PF08690.10 EGD87884.2 - 1.3 8.7 2.4 2.1 7.9 2.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF3632 PF12311.8 EGD87888.2 - 4.2e-44 151.0 10.7 5.5e-44 150.7 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) RNA_pol_Rpb2_6 PF00562.28 EGD87889.1 - 3.3e-124 414.9 0.0 5.5e-124 414.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGD87889.1 - 1.1e-55 188.3 0.4 1.7e-55 187.7 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EGD87889.1 - 8.5e-31 106.2 0.4 2e-30 105.0 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EGD87889.1 - 1.5e-29 103.0 1.8 3.7e-29 101.7 1.6 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EGD87889.1 - 9.4e-26 89.9 0.6 2.9e-25 88.3 0.6 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EGD87889.1 - 3.3e-18 65.6 0.0 7.7e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EGD87889.1 - 2e-11 44.2 0.5 7e-11 42.5 0.5 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L22e PF01776.17 EGD87889.1 - 0.19 12.1 0.9 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal L22e protein family PUF PF00806.19 EGD87890.1 - 1.2e-56 185.3 7.9 1.8e-07 30.5 0.0 9.0 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat LolA_2 PF16584.5 EGD87890.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA ORC5_C PF14630.6 EGD87891.1 - 3.7e-78 262.9 0.0 4.7e-78 262.6 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EGD87891.1 - 2.5e-20 73.5 0.0 4.8e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EGD87891.1 - 6.5e-06 26.2 0.1 0.032 14.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain T2SSE PF00437.20 EGD87891.1 - 0.00075 18.6 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGD87891.1 - 0.0016 18.7 0.0 0.0034 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGD87891.1 - 0.0079 15.9 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGD87891.1 - 0.009 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EGD87891.1 - 0.01 16.4 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 EGD87891.1 - 0.012 16.1 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EGD87891.1 - 0.013 14.8 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.18 EGD87891.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 EGD87891.1 - 0.019 15.1 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGD87891.1 - 0.029 14.4 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EGD87891.1 - 0.047 13.1 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Septin PF00735.18 EGD87891.1 - 0.079 12.2 0.1 1.5 8.0 0.0 2.5 2 1 1 3 3 3 0 Septin cobW PF02492.19 EGD87891.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EGD87891.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EGD87891.1 - 0.11 12.0 0.0 0.54 9.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_27 PF13514.6 EGD87891.1 - 0.13 11.9 0.9 8.2 6.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 EGD87891.1 - 0.13 12.7 0.1 0.42 11.1 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EGD87891.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.17 EGD87891.1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 EGD87891.1 - 0.2 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EGD87891.1 - 0.21 11.6 0.0 0.73 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.21 EGD87891.1 - 0.21 11.3 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase NB-ARC PF00931.22 EGD87891.1 - 0.28 10.4 0.0 0.43 9.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_Eps PF04627.13 EGD87893.1 - 1.3e-21 76.3 0.4 1.6e-21 76.0 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DTHCT PF08070.11 EGD87894.1 - 5.2 7.9 18.0 0.21 12.4 11.2 1.9 2 0 0 2 2 2 0 DTHCT (NUC029) region Cpn60_TCP1 PF00118.24 EGD87895.2 - 1.1e-78 265.0 11.1 2.7e-72 244.0 9.1 2.2 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.20 EGD87896.1 - 5e-34 116.7 0.0 5.6e-34 116.5 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein COX4 PF02936.14 EGD87897.2 - 8.4e-38 129.5 0.4 1.2e-37 129.0 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 EGD87897.2 - 0.015 15.8 2.6 0.015 15.8 2.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1104 PF06518.11 EGD87897.2 - 0.065 13.6 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DUF1138 PF06592.13 EGD87897.2 - 0.1 12.7 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) ATP-synt_ab PF00006.25 EGD87899.2 - 6.1e-62 209.0 0.0 1e-61 208.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGD87899.2 - 1.3e-21 76.9 1.9 1.1e-20 74.0 2.6 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 EGD87899.2 - 0.011 16.2 0.0 0.65 10.4 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EGD87899.2 - 0.013 15.5 0.6 0.033 14.1 0.0 1.9 3 0 0 3 3 3 0 RsgA GTPase NB-ARC PF00931.22 EGD87899.2 - 0.021 14.0 0.3 0.1 11.8 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EGD87899.2 - 0.032 14.2 0.0 0.085 12.7 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGD87899.2 - 0.033 14.5 1.0 0.51 10.7 0.2 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGD87899.2 - 0.042 13.8 0.2 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 EGD87899.2 - 0.05 12.9 0.2 0.091 12.1 0.2 1.4 1 0 0 1 1 1 0 KaiC T3SS_ATPase_C PF18269.1 EGD87899.2 - 0.062 13.2 0.8 0.3 11.0 0.8 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RNA_helicase PF00910.22 EGD87899.2 - 0.084 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EGD87899.2 - 0.1 12.9 0.1 0.39 11.1 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain BBE PF08031.12 EGD87900.2 - 1.6e-10 40.9 0.2 3.5e-10 39.8 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EGD87900.2 - 1e-09 38.3 4.1 2.4e-09 37.1 4.1 1.6 1 0 0 1 1 1 1 FAD binding domain DUF4875 PF16175.5 EGD87900.2 - 0.096 12.8 0.3 0.32 11.1 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4875) AAA_2 PF07724.14 EGD87903.1 - 3.1e-38 131.6 0.0 3.9e-37 128.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGD87903.1 - 1.1e-14 54.9 0.0 2.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGD87903.1 - 2.7e-09 36.9 0.3 8.9e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EGD87903.1 - 1.6e-06 28.1 0.0 3.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGD87903.1 - 0.00016 21.1 0.1 0.0075 15.7 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGD87903.1 - 0.0003 20.5 0.0 0.093 12.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 EGD87903.1 - 0.0024 17.0 0.5 0.0063 15.6 0.1 1.8 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 EGD87903.1 - 0.0027 18.1 0.1 0.01 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGD87903.1 - 0.0037 17.5 0.3 0.032 14.5 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGD87903.1 - 0.0047 16.7 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGD87903.1 - 0.0048 16.6 0.2 0.074 12.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGD87903.1 - 0.0052 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 EGD87903.1 - 0.041 13.4 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGD87903.1 - 0.055 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EGD87903.1 - 0.056 14.0 0.3 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGD87903.1 - 0.057 13.9 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EGD87903.1 - 0.069 13.3 0.6 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EGD87903.1 - 0.091 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGD87903.1 - 0.091 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGD87903.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ras PF00071.22 EGD87905.1 - 3.9e-63 211.9 0.2 4.6e-63 211.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD87905.1 - 3e-35 121.1 0.2 4.2e-35 120.6 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD87905.1 - 2e-13 50.1 0.1 2.6e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGD87905.1 - 1.2e-07 31.7 0.1 2e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGD87905.1 - 0.00016 21.6 1.3 0.017 15.0 0.2 2.2 1 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EGD87905.1 - 0.00021 20.9 0.1 0.00091 18.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGD87905.1 - 0.00055 19.4 0.1 0.00088 18.7 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EGD87905.1 - 0.0017 18.7 0.1 0.013 15.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.10 EGD87905.1 - 0.0077 15.7 0.0 0.013 14.9 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EGD87905.1 - 0.014 15.4 0.1 0.048 13.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGD87905.1 - 0.014 15.7 0.1 0.026 14.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EGD87905.1 - 0.017 15.6 0.1 0.025 15.1 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EGD87905.1 - 0.024 14.4 0.1 0.061 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EGD87905.1 - 0.035 13.5 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein SpoIIID PF12116.8 EGD87905.1 - 0.038 14.1 0.1 0.81 9.8 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D MCM PF00493.23 EGD87905.1 - 0.091 11.8 0.0 0.22 10.6 0.0 1.7 1 1 0 1 1 1 0 MCM P-loop domain AAA_21 PF13304.6 EGD87905.1 - 0.097 12.5 0.9 0.13 12.0 0.9 1.7 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EGD87905.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 EGD87905.1 - 0.11 12.0 0.1 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B F-box-like PF12937.7 EGD87906.1 - 1.1e-07 31.6 0.3 8.5e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGD87906.1 - 0.0016 18.3 0.1 0.008 16.0 0.1 2.2 2 0 0 2 2 2 1 F-box domain Brix PF04427.18 EGD87907.2 - 3.2e-16 60.0 0.0 4.4e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain Elongin_A PF06881.11 EGD87907.2 - 0.024 15.2 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Protocadherin PF08374.11 EGD87907.2 - 0.055 13.5 0.8 0.14 12.1 0.3 1.7 2 0 0 2 2 2 0 Protocadherin WW PF00397.26 EGD87908.1 - 2.7e-10 40.2 2.5 7.4e-10 38.8 2.5 1.8 1 0 0 1 1 1 1 WW domain DUF3623 PF12291.8 EGD87910.2 - 0.036 13.3 1.3 0.058 12.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) Abp2 PF09441.10 EGD87911.1 - 9.5e-86 286.2 0.1 1.6e-85 285.4 0.1 1.3 1 0 0 1 1 1 1 ARS binding protein 2 ORC6 PF05460.13 EGD87912.1 - 0.045 13.0 6.6 0.057 12.7 6.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF4366 PF14283.6 EGD87917.2 - 0.024 14.7 0.3 0.12 12.4 0.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF5305 PF17231.2 EGD87917.2 - 0.05 13.0 1.1 0.074 12.4 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Apt1 PF10351.9 EGD87917.2 - 0.19 10.6 1.5 0.21 10.4 1.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 EGD87917.2 - 0.34 10.1 10.5 0.37 9.9 10.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MGC-24 PF05283.11 EGD87917.2 - 2.6 8.5 16.6 1.3 9.5 6.1 2.2 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF829 PF05705.14 EGD87921.1 - 4e-49 167.7 0.0 4.6e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Varsurf_PPLC PF03490.13 EGD87921.1 - 0.051 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C UFD1 PF03152.14 EGD87922.1 - 1.7e-75 252.2 0.0 2.3e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 EGD87922.1 - 0.052 13.3 0.0 0.79 9.6 0.0 2.2 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 GYF PF02213.16 EGD87923.1 - 1.6e-07 30.9 1.3 3.8e-07 29.7 1.3 1.7 1 0 0 1 1 1 1 GYF domain TIP49 PF06068.13 EGD87924.1 - 3.1e-153 510.1 1.4 4.7e-153 509.5 1.4 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGD87924.1 - 2.2e-21 75.7 0.8 7.6e-21 74.0 0.2 2.3 3 0 0 3 3 3 1 TIP49 AAA-lid domain AAA PF00004.29 EGD87924.1 - 6.2e-08 33.1 0.1 8.8e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGD87924.1 - 1.9e-07 31.0 0.5 0.0002 21.2 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGD87924.1 - 2e-05 25.0 0.1 5.9e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 EGD87924.1 - 4.8e-05 22.8 0.6 8.7e-05 22.0 0.6 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 EGD87924.1 - 0.002 17.6 0.8 0.026 13.9 0.3 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGD87924.1 - 0.0079 16.2 0.1 0.61 10.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGD87924.1 - 0.014 15.6 0.0 0.96 9.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGD87924.1 - 0.024 14.3 0.0 8.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 EGD87924.1 - 0.049 14.0 1.6 1.7 8.9 1.6 2.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGD87924.1 - 0.052 13.1 0.1 0.099 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGD87924.1 - 0.067 13.3 0.1 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EGD87924.1 - 0.088 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 EGD87924.1 - 0.12 11.9 0.2 0.48 9.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF1664 PF07889.12 EGD87925.1 - 0.00016 21.7 24.2 0.37 10.8 0.5 5.0 4 2 0 4 4 4 4 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EGD87925.1 - 0.00032 20.8 34.9 0.027 14.5 0.4 6.0 3 1 2 6 6 6 4 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 EGD87925.1 - 0.00033 20.4 6.9 0.76 9.7 0.0 5.8 6 0 0 6 6 5 1 Heat shock factor binding protein 1 Atg14 PF10186.9 EGD87925.1 - 0.00048 19.3 33.4 0.24 10.4 1.3 3.9 1 1 1 3 3 3 3 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 EGD87925.1 - 0.0027 17.1 0.1 0.0027 17.1 0.1 5.2 3 2 2 5 5 5 2 Growth-arrest specific micro-tubule binding MtrB PF05440.12 EGD87925.1 - 0.047 14.1 3.7 24 5.4 0.0 5.0 4 2 0 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B CENP-F_leu_zip PF10473.9 EGD87925.1 - 0.11 12.5 34.5 0.045 13.8 0.9 5.3 4 2 0 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 EGD87925.1 - 0.11 11.7 25.6 1.7 7.8 0.4 4.8 2 2 2 5 5 5 0 TMPIT-like protein WXG100 PF06013.12 EGD87925.1 - 0.12 12.6 14.2 4.3 7.6 0.7 6.6 4 2 1 5 5 5 0 Proteins of 100 residues with WXG Sec8_exocyst PF04048.14 EGD87925.1 - 0.19 11.6 20.3 0.037 13.9 5.6 4.5 4 1 0 4 4 4 0 Sec8 exocyst complex component specific domain HrpB7 PF09486.10 EGD87925.1 - 0.29 11.5 20.7 0.12 12.7 4.6 4.3 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) COG2 PF06148.11 EGD87925.1 - 0.7 10.0 19.9 2.3 8.3 0.4 5.7 3 2 1 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.10 EGD87925.1 - 0.88 9.8 33.8 0.16 12.2 1.0 6.4 3 2 3 6 6 6 0 Cortexillin I, coiled coil Vip3A_N PF12495.8 EGD87925.1 - 1 9.3 5.7 0.55 10.1 0.2 3.0 3 1 0 3 3 3 0 Vegetative insecticide protein 3A N terminal Phasin PF05597.11 EGD87925.1 - 1.2 9.2 23.8 1.2 9.1 0.9 5.3 4 1 1 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Nup54 PF13874.6 EGD87925.1 - 1.3 9.1 26.9 0.27 11.4 5.3 4.6 3 1 0 3 3 3 0 Nucleoporin complex subunit 54 Spc7 PF08317.11 EGD87925.1 - 1.3 7.8 41.7 0.12 11.2 10.9 4.6 2 1 0 4 4 4 0 Spc7 kinetochore protein DUF4254 PF14063.6 EGD87925.1 - 1.3 8.8 12.1 4.6 7.0 0.6 4.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4254) Fib_alpha PF08702.10 EGD87925.1 - 2 8.6 38.1 3.8 7.7 2.3 5.6 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 EGD87925.1 - 2.3 8.9 37.0 0.18 12.5 8.6 5.6 4 3 3 7 7 7 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FlaC_arch PF05377.11 EGD87925.1 - 2.4 8.6 28.5 0.46 10.9 1.2 7.1 6 2 2 8 8 8 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 EGD87925.1 - 2.6 7.3 35.4 0.55 9.5 10.3 4.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Prominin PF05478.11 EGD87925.1 - 2.7 5.9 27.1 0.21 9.5 8.1 3.1 1 1 2 3 3 3 0 Prominin BLOC1_2 PF10046.9 EGD87925.1 - 3.2 8.1 28.2 0.51 10.7 1.6 7.0 4 3 4 8 8 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4988 PF16378.5 EGD87925.1 - 7.4 6.2 11.4 13 5.5 0.1 4.8 4 2 1 5 5 5 0 Domain of unknown function YtxH PF12732.7 EGD87925.1 - 7.7 7.1 18.6 13 6.4 0.2 5.2 4 1 0 4 4 4 0 YtxH-like protein COG5 PF10392.9 EGD87925.1 - 7.9 6.7 25.2 0.86 9.8 6.8 4.6 3 1 0 4 4 4 0 Golgi transport complex subunit 5 SlyX PF04102.12 EGD87925.1 - 9.4 6.9 21.6 4.3 8.0 0.8 7.0 3 3 5 8 8 8 0 SlyX FSH1 PF03959.13 EGD87926.1 - 9.3e-29 100.6 0.0 1.2e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EGD87926.1 - 0.028 14.2 0.6 1.1 9.0 0.3 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EGD87926.1 - 0.048 13.3 0.0 0.099 12.3 0.0 1.5 1 1 1 2 2 2 0 alpha/beta hydrolase fold Peptidase_M14 PF00246.24 EGD87928.1 - 1.9e-80 270.8 0.0 8.7e-80 268.6 0.0 1.8 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EGD87928.1 - 4.5e-10 39.8 1.6 1.1e-09 38.6 0.1 2.4 3 0 0 3 3 3 1 Carboxypeptidase activation peptide AstE_AspA PF04952.14 EGD87928.1 - 0.19 10.8 0.1 0.31 10.1 0.1 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Thioredoxin PF00085.20 EGD87929.1 - 0.0014 18.5 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Osteopontin PF00865.18 EGD87929.1 - 0.064 12.7 17.9 0.086 12.3 8.3 2.2 2 0 0 2 2 2 0 Osteopontin SMI1_KNR4 PF09346.10 EGD87930.1 - 1.1e-33 116.4 0.0 2.3e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PNRC PF15365.6 EGD87932.1 - 9.9e-09 34.8 7.7 9.9e-09 34.8 7.7 5.2 7 0 0 7 7 7 1 Proline-rich nuclear receptor coactivator motif zf-rbx1 PF12678.7 EGD87933.1 - 5.5e-25 87.4 12.5 7.7e-25 86.9 12.5 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGD87933.1 - 6.3e-17 61.4 9.8 8.2e-17 61.0 9.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EGD87933.1 - 2.3e-06 27.8 14.7 8e-05 22.9 14.7 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGD87933.1 - 5e-05 23.1 3.3 5e-05 23.1 3.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGD87933.1 - 0.0026 17.6 11.7 0.045 13.6 11.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGD87933.1 - 0.12 12.6 8.9 0.56 10.4 9.0 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 EGD87933.1 - 0.41 10.5 10.8 0.83 9.6 4.4 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD87933.1 - 0.6 10.2 8.2 2.2 8.4 8.2 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EGD87933.1 - 0.69 9.6 14.3 1e+02 2.6 14.3 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EGD87933.1 - 1.1 9.0 17.1 1e+02 2.8 17.1 2.5 1 1 0 1 1 1 0 RING-like zinc finger MFS_1 PF07690.16 EGD87935.2 - 8e-16 57.9 29.0 7.4e-15 54.7 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YqcI_YcgG PF08892.11 EGD87936.1 - 3.9e-67 226.2 0.1 4.9e-67 225.8 0.1 1.1 1 0 0 1 1 1 1 YqcI/YcgG family CorA PF01544.18 EGD87937.1 - 4.5e-41 141.1 0.0 5.9e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Mid1 PF12929.7 EGD87938.2 - 4.7e-150 500.5 3.3 5.7e-150 500.2 3.3 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EGD87938.2 - 0.00026 21.6 7.2 0.015 15.9 3.0 2.5 2 0 0 2 2 2 2 Fz domain Es2 PF09751.9 EGD87939.2 - 4.9e-138 461.5 17.8 5.8e-138 461.3 17.8 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 SGL PF08450.12 EGD87945.1 - 4.7e-27 95.2 0.7 1.4e-25 90.3 0.7 2.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EGD87945.1 - 0.06 13.5 0.0 1.2 9.4 0.0 2.9 3 1 0 3 3 3 0 Strictosidine synthase TPR_2 PF07719.17 EGD87946.1 - 9e-26 87.9 24.3 0.0042 17.1 0.2 12.4 12 0 0 12 12 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 EGD87946.1 - 7e-23 79.5 21.4 0.0013 18.5 0.1 11.6 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_19 PF14559.6 EGD87946.1 - 2.6e-17 63.1 34.6 0.00021 21.7 0.0 10.3 9 3 1 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGD87946.1 - 9.5e-15 53.5 24.5 0.085 13.1 0.1 11.8 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGD87946.1 - 5.1e-14 51.8 35.6 0.004 17.8 0.1 12.7 12 1 0 13 13 12 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGD87946.1 - 5.7e-09 36.2 33.0 0.0035 17.6 2.5 9.2 7 3 3 10 10 10 5 Tetratricopeptide repeat TPR_6 PF13174.6 EGD87946.1 - 1.1e-07 32.0 30.6 0.03 15.0 0.1 13.0 15 0 0 15 15 14 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGD87946.1 - 3.8e-07 30.6 30.6 0.22 12.2 0.4 9.2 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGD87946.1 - 3.1e-05 24.0 22.5 0.14 12.6 0.1 10.2 12 0 0 12 12 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGD87946.1 - 9.3e-05 22.0 30.0 0.05 13.3 0.4 9.4 10 1 1 11 11 10 2 TPR repeat TPR_4 PF07721.14 EGD87946.1 - 0.0026 18.2 2.3 22 6.0 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGD87946.1 - 0.0055 16.7 32.9 0.28 11.3 0.2 9.3 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGD87946.1 - 0.035 14.0 0.3 0.035 14.0 0.3 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat CCP_MauG PF03150.14 EGD87946.1 - 0.27 11.9 2.1 2.7 8.6 0.0 3.3 3 1 0 3 3 3 0 Di-haem cytochrome c peroxidase Fis1_TPR_C PF14853.6 EGD87946.1 - 3.6 7.7 7.4 5.3 7.2 0.1 4.3 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 EGD87946.1 - 4.6 7.3 14.2 85 3.3 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Acyltransferase PF01553.21 EGD87947.1 - 1.3e-27 96.0 0.0 2.2e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EGD87947.1 - 3.6e-14 52.6 0.1 7.2e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_kinase PF01513.21 EGD87948.1 - 2.6e-48 164.7 0.1 4.1e-48 164.1 0.1 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EGD87948.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 EGD87949.1 - 4.7e-67 226.1 0.3 4.6e-66 222.9 0.3 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87949.1 - 1.8e-50 171.6 0.0 3.5e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EGD87949.1 - 5.4e-24 84.3 0.0 5.4e-24 84.3 0.0 2.5 3 0 0 3 3 3 1 P21-Rho-binding domain PH_11 PF15413.6 EGD87949.1 - 3.2e-15 56.5 0.1 8.6e-15 55.1 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 EGD87949.1 - 2.2e-05 23.9 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGD87949.1 - 2.5e-05 23.3 0.0 2.5e-05 23.3 0.0 2.2 3 1 0 3 3 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EGD87949.1 - 4.5e-05 22.6 0.1 9.3e-05 21.5 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain PH PF00169.29 EGD87949.1 - 0.00016 22.1 0.1 0.0004 20.9 0.1 1.7 1 0 0 1 1 1 1 PH domain KIND PF16474.5 EGD87949.1 - 0.028 14.3 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Seadorna_VP7 PF07387.11 EGD87949.1 - 0.039 13.0 0.1 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EGD87949.1 - 1.5 8.7 5.6 1 9.3 0.3 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family HGTP_anticodon PF03129.20 EGD87951.1 - 1.1e-19 70.4 2.5 4.2e-19 68.5 0.0 3.0 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGD87951.1 - 3e-09 37.1 0.0 2.2e-08 34.3 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Brix PF04427.18 EGD87952.1 - 8.7e-23 81.4 0.0 1.3e-22 80.9 0.0 1.3 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.12 EGD87952.1 - 8.8 4.4 18.9 11 4.0 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family SET PF00856.28 EGD87954.2 - 5.5e-18 65.9 3.9 8.3e-18 65.3 0.4 2.8 2 1 0 2 2 2 1 SET domain AWS PF17907.1 EGD87954.2 - 1.1e-10 41.3 11.9 1.1e-10 41.3 11.9 2.8 2 0 0 2 2 2 1 AWS domain SRI PF08236.11 EGD87954.2 - 3.1e-09 36.9 2.4 1.2e-08 35.0 2.4 2.1 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.11 EGD87954.2 - 1e-05 25.4 0.2 2.3e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.26 EGD87954.2 - 0.021 14.9 0.3 0.065 13.3 0.3 1.9 1 0 0 1 1 1 0 WW domain SARS_X4 PF08779.10 EGD87957.2 - 0.093 12.9 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 SARS coronavirus X4 like F-box PF00646.33 EGD87957.2 - 0.15 12.0 0.7 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 F-box domain AT_hook PF02178.19 EGD87959.2 - 0.011 15.5 1.5 0.06 13.2 1.5 2.3 1 0 0 1 1 1 0 AT hook motif BAR PF03114.18 EGD87960.1 - 2.1e-65 220.7 5.1 2.7e-65 220.4 5.1 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 EGD87960.1 - 0.0078 16.9 0.7 0.03 15.1 0.0 2.4 3 2 0 3 3 3 1 CP12 domain DUF2884 PF11101.8 EGD87960.1 - 0.24 10.9 4.2 1.5 8.3 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2884) FliD_N PF02465.18 EGD87960.1 - 2.9 8.6 6.1 25 5.6 0.2 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Pkinase PF00069.25 EGD87961.1 - 9.4e-50 169.4 0.0 1.3e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87961.1 - 3.3e-27 95.4 0.0 4.5e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGD87961.1 - 0.0082 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGD87961.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Sybindin PF04099.12 EGD87962.1 - 6.5e-25 87.7 0.0 8.2e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EGD87962.1 - 0.0035 17.5 0.1 0.0048 17.0 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.25 EGD87963.1 - 8.1e-57 192.6 0.1 4.9e-51 173.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87963.1 - 3.2e-35 121.7 0.1 2.4e-33 115.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGD87963.1 - 9.1e-09 35.0 0.0 4.8e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGD87963.1 - 0.0016 17.3 0.1 0.011 14.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGD87963.1 - 0.0024 17.8 0.1 0.0053 16.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pept_tRNA_hydro PF01195.19 EGD87964.1 - 3.2e-23 82.6 0.0 1.4e-11 44.7 0.1 2.8 1 1 0 2 2 2 2 Peptidyl-tRNA hydrolase Methyltransf_23 PF13489.6 EGD87966.2 - 6.7e-12 45.5 0.0 1.8e-11 44.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD87966.2 - 2.4e-08 34.6 0.0 4.9e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD87966.2 - 1.9e-07 31.0 0.0 3.6e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD87966.2 - 5.8e-06 27.0 0.0 2e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD87966.2 - 0.00096 19.8 0.0 0.0018 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGD87966.2 - 0.0026 17.3 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 EGD87966.2 - 0.0033 17.6 0.0 0.049 13.7 0.0 2.2 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EGD87966.2 - 0.0098 15.2 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 EGD87966.2 - 0.011 15.2 0.0 0.028 13.9 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase DUF938 PF06080.12 EGD87966.2 - 0.067 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) AAA_28 PF13521.6 EGD87966.2 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NADHdh-2_N PF12155.8 EGD87966.2 - 0.13 12.6 0.2 0.44 11.0 0.1 1.9 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal UQ_con PF00179.26 EGD87968.1 - 1.1e-48 164.4 0.0 1.3e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Scramblase PF03803.15 EGD87969.1 - 4e-56 189.8 0.0 1.3e-54 184.8 0.0 2.7 1 1 0 1 1 1 1 Scramblase Ribosomal_L27 PF01016.19 EGD87971.1 - 7.8e-32 109.1 1.0 1.4e-31 108.4 1.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Tudor_3 PF18115.1 EGD87972.1 - 2.2e-16 59.4 0.0 4.3e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Rad9_Rad53_bind PF08605.10 EGD87972.1 - 5e-16 59.1 0.0 9.5e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 EGD87972.1 - 1.5e-07 31.7 0.0 4.9e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGD87972.1 - 1.3e-06 28.7 0.0 3.3e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EGD87972.1 - 7.8e-05 22.5 0.0 0.0004 20.2 0.0 2.1 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain Anillin_N PF16018.5 EGD87972.1 - 0.061 13.9 8.2 0.56 10.8 0.1 4.9 3 1 1 4 4 4 0 Anillin N-terminus BRCT_3 PF18428.1 EGD87972.1 - 0.086 12.9 0.2 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Nop10p PF04135.12 EGD87974.2 - 5.5e-22 77.6 0.6 7.3e-22 77.2 0.6 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.11 EGD87975.1 - 8.2e-33 112.4 3.2 1.6e-32 111.4 3.2 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EGD87975.1 - 1.9e-30 105.2 0.2 1.8e-29 102.0 0.1 2.6 3 0 0 3 3 3 1 PIN domain of ribonuclease HypA PF01155.19 EGD87975.1 - 0.003 17.6 0.2 0.12 12.4 0.2 2.4 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 EGD87975.1 - 0.027 14.1 3.1 0.032 13.9 0.4 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Cript PF10235.9 EGD87975.1 - 0.2 12.2 1.4 0.3 11.7 0.5 1.8 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Zn-ribbon_8 PF09723.10 EGD87975.1 - 0.79 9.9 6.1 0.26 11.4 1.3 2.3 2 0 0 2 2 2 0 Zinc ribbon domain ABC_tran PF00005.27 EGD87977.1 - 6e-51 172.6 0.0 1.7e-25 90.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EGD87977.1 - 9.5e-24 84.1 41.5 4.9e-14 52.2 23.9 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EGD87977.1 - 6.1e-23 82.1 1.1 0.00012 22.0 0.0 4.4 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGD87977.1 - 8.8e-10 38.4 1.1 0.004 16.6 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGD87977.1 - 2.9e-09 36.5 1.7 6.9e-05 22.5 0.4 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGD87977.1 - 9.1e-08 32.8 2.9 0.007 16.9 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 EGD87977.1 - 6.8e-06 25.8 0.4 0.099 12.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGD87977.1 - 1.8e-05 24.7 0.2 0.058 13.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EGD87977.1 - 5.5e-05 23.0 0.0 0.026 14.2 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain DUF4162 PF13732.6 EGD87977.1 - 0.00026 21.6 0.1 0.011 16.4 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) AAA_16 PF13191.6 EGD87977.1 - 0.00059 20.3 0.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EGD87977.1 - 0.00061 19.6 0.8 0.42 10.3 0.2 3.0 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 EGD87977.1 - 0.006 16.8 0.2 8 6.8 0.1 4.0 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 EGD87977.1 - 0.018 15.3 0.1 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGD87977.1 - 0.025 14.2 0.7 2.9 7.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EGD87977.1 - 0.046 13.3 0.5 8.4 6.0 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 EGD87977.1 - 0.061 13.4 0.6 4 7.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EGD87977.1 - 0.079 12.2 0.1 11 5.3 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 EGD87977.1 - 0.2 11.9 0.2 25 5.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 EGD87978.2 - 9e-36 123.5 25.3 1.1e-35 123.2 23.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ATPase_gene1 PF09527.10 EGD87978.2 - 0.1 12.8 0.3 0.1 12.8 0.3 5.5 6 1 0 6 6 6 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter ABC2_membrane PF01061.24 EGD87979.1 - 7.2e-79 264.1 54.5 3.8e-40 137.6 27.8 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGD87979.1 - 3.2e-34 118.4 0.0 9.7e-17 61.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGD87979.1 - 5.4e-20 71.1 0.0 5.4e-20 71.1 0.0 2.3 2 0 0 2 2 1 1 CDR ABC transporter ABC_trans_N PF14510.6 EGD87979.1 - 9.7e-12 45.3 0.0 1.2e-10 41.9 0.0 2.7 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_21 PF13304.6 EGD87979.1 - 1.2e-05 25.3 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EGD87979.1 - 3.3e-05 24.1 0.2 0.0015 18.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGD87979.1 - 0.00014 22.3 0.1 0.015 15.7 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EGD87979.1 - 0.00017 22.1 0.0 0.0037 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EGD87979.1 - 0.0013 17.9 45.9 0.005 16.0 22.3 3.3 2 1 1 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGD87979.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGD87979.1 - 0.0025 17.5 0.6 0.015 15.0 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EGD87979.1 - 0.0032 17.1 0.1 0.018 14.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EGD87979.1 - 0.0037 17.5 0.0 0.11 12.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EGD87979.1 - 0.01 15.3 0.0 0.69 9.3 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 EGD87979.1 - 0.058 13.8 0.1 0.3 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGD87979.1 - 0.076 12.6 0.4 0.17 11.5 0.4 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EGD87979.1 - 0.15 12.4 0.8 0.4 11.0 0.2 2.2 2 1 0 2 2 1 0 AAA domain AAA_23 PF13476.6 EGD87979.1 - 0.35 11.3 0.0 0.35 11.3 0.0 2.2 3 0 0 3 3 2 0 AAA domain Adap_comp_sub PF00928.21 EGD87981.1 - 1e-83 280.8 0.0 1.6e-83 280.1 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGD87981.1 - 1.8e-09 37.7 0.1 3e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EGD87981.1 - 0.15 11.5 0.0 0.35 10.3 0.0 1.5 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.6 EGD87982.1 - 5.2e-28 97.8 0.0 8.3e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGD87982.1 - 1.3e-05 25.8 0.0 3.4e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Sdh_cyt PF01127.22 EGD87983.2 - 5.5e-24 84.5 4.2 5.5e-24 84.5 4.2 1.8 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit bZIP_1 PF00170.21 EGD87983.2 - 0.18 11.9 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 bZIP transcription factor NMO PF03060.15 EGD87984.2 - 9.4e-37 127.1 0.3 2e-36 126.1 0.3 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGD87984.2 - 8.5e-06 25.0 0.5 1.9e-05 23.8 0.4 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGD87984.2 - 0.00086 18.4 0.1 0.0014 17.7 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 EGD87984.2 - 0.011 14.9 0.1 0.033 13.4 0.0 1.7 1 1 1 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase SCP1201-deam PF14428.6 EGD87985.1 - 0.005 16.7 0.2 0.019 14.8 0.2 2.0 1 0 0 1 1 1 1 SCP1.201-like deaminase Hydrophobin PF01185.18 EGD87986.2 - 5.9e-06 26.8 7.2 1.1e-05 25.9 7.2 1.4 1 0 0 1 1 1 1 Fungal hydrophobin ATP_sub_h PF10775.9 EGD87986.2 - 0.0046 16.9 0.2 0.011 15.8 0.2 1.6 1 0 0 1 1 1 1 ATP synthase complex subunit h WW PF00397.26 EGD87987.1 - 3.5e-10 39.8 2.0 3.5e-10 39.8 2.0 2.3 2 0 0 2 2 2 1 WW domain WRW PF10206.9 EGD87987.1 - 0.09 13.2 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Ank_2 PF12796.7 EGD87988.1 - 5.2e-13 49.4 0.4 7e-12 45.8 0.4 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGD87988.1 - 5e-11 42.5 0.2 8.2e-07 29.2 0.2 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGD87988.1 - 4.1e-10 39.7 1.8 2.3e-07 30.9 0.5 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD87988.1 - 3.8e-09 36.0 0.3 6.4e-06 26.1 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGD87988.1 - 1.8e-08 34.8 0.1 9e-08 32.5 0.1 2.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Glyco_transf_21 PF13506.6 EGD87989.1 - 7.1e-14 51.7 0.0 6.2e-07 29.1 0.0 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EGD87989.1 - 2.4e-07 30.9 0.0 5.1e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF2621 PF11084.8 EGD87989.1 - 0.45 10.5 1.6 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) Cation_ATPase_C PF00689.21 EGD87990.2 - 4.1e-39 134.2 6.5 4.1e-39 134.2 6.5 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGD87990.2 - 3.6e-37 127.6 1.0 3.6e-37 127.6 1.0 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGD87990.2 - 2.7e-24 86.6 0.2 4.7e-11 43.4 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGD87990.2 - 9.6e-16 57.6 0.0 2e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGD87990.2 - 7.4e-06 25.9 0.2 4.2e-05 23.4 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGD87990.2 - 0.0028 18.1 0.0 0.029 14.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 EGD87990.2 - 0.077 12.8 13.1 0.97 9.2 0.5 3.6 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) Rnf-Nqr PF02508.14 EGD87990.2 - 0.16 12.0 6.5 0.18 11.7 1.2 2.6 2 0 0 2 2 2 0 Rnf-Nqr subunit, membrane protein PGG PF13962.6 EGD87990.2 - 0.31 10.9 7.7 0.12 12.2 0.6 2.9 2 0 0 2 2 2 0 Domain of unknown function Sigma_reg_N PF13800.6 EGD87990.2 - 2.3 8.6 5.7 1.2 9.4 0.7 2.9 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF3262 PF11660.8 EGD87990.2 - 3.1 8.3 7.8 32 5.0 2.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) HAT_KAT11 PF08214.11 EGD87991.1 - 1e-93 314.4 0.0 1.3e-93 314.1 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein DUF3290 PF11694.8 EGD87991.1 - 0.2 11.7 0.4 0.82 9.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Cupin_2 PF07883.11 EGD87992.1 - 2.7e-07 30.2 0.1 4.4e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 EGD87992.1 - 0.022 14.7 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Hid1 PF12722.7 EGD87994.2 - 2.1e-209 697.7 0.0 2.4e-209 697.5 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EGD87994.2 - 3.6e-62 210.7 0.0 4.3e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein BC10 PF06726.12 EGD87994.2 - 0.065 13.5 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 Vps54 PF07928.12 EGD87997.2 - 2.9e-50 170.2 0.0 1.2e-49 168.2 0.0 2.1 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.9 EGD87997.2 - 2e-08 34.3 0.2 1.2e-07 31.8 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 EGD87997.2 - 0.001 18.5 2.2 0.0011 18.3 0.4 2.0 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Cytochrom_B562 PF07361.11 EGD87997.2 - 0.021 15.5 0.2 0.079 13.6 0.2 2.0 1 0 0 1 1 1 0 Cytochrome b562 Pkinase PF00069.25 EGD87998.2 - 2.1e-20 73.2 0.0 1.2e-19 70.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD87998.2 - 6.1e-09 35.5 0.0 0.0024 17.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD87998.2 - 0.028 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGD87998.2 - 0.093 12.6 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ECH_1 PF00378.20 EGD88001.1 - 4.2e-36 124.5 0.1 1.5e-23 83.4 0.1 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGD88001.1 - 4.2e-17 62.7 0.0 3e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase PfkB PF00294.24 EGD88002.1 - 2.2e-39 135.6 0.1 6.4e-39 134.1 0.1 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase p6 PF17548.2 EGD88002.1 - 0.069 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Histone-like Protein p6 PAN_1 PF00024.26 EGD88003.1 - 1.5e-05 24.8 3.1 3.2e-05 23.8 3.1 1.5 1 0 0 1 1 1 1 PAN domain 2OG-FeII_Oxy_3 PF13640.6 EGD88005.1 - 2.8e-09 37.7 0.0 4.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Astro_capsid_p PF12226.8 EGD88007.2 - 1.4 8.0 6.7 2.5 7.1 6.7 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FAT PF02259.23 EGD88009.2 - 9.1e-72 242.2 13.3 1.9e-71 241.1 13.3 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EGD88009.2 - 9e-36 124.0 0.1 2.3e-35 122.6 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EGD88009.2 - 6.9e-06 25.8 0.1 2e-05 24.3 0.1 1.9 1 0 0 1 1 1 1 FATC domain Gluconate_2-dh3 PF13618.6 EGD88009.2 - 0.025 14.8 0.1 3.9 7.7 0.0 3.0 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 DUF2576 PF10845.8 EGD88009.2 - 0.11 12.1 0.0 0.38 10.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) DUF572 PF04502.13 EGD88010.1 - 3e-70 237.5 13.6 3.5e-70 237.3 13.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF951 PF06107.11 EGD88010.1 - 0.043 13.7 0.1 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) HypA PF01155.19 EGD88010.1 - 0.071 13.1 0.6 2 8.5 0.1 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_RNApol_7kD PF03604.13 EGD88010.1 - 0.11 12.2 2.4 7.8 6.3 0.4 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-FCS PF06467.14 EGD88010.1 - 0.12 12.4 3.6 0.75 9.8 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF866 PF05907.13 EGD88010.1 - 0.18 11.7 3.8 0.15 11.9 1.8 1.7 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF866) TF_Zn_Ribbon PF08271.12 EGD88010.1 - 0.53 9.8 6.0 0.88 9.1 1.3 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 EGD88010.1 - 0.77 9.6 3.6 1.1 9.0 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 EGD88010.1 - 2.2 8.4 5.5 3.4 7.8 0.8 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Zn_ribbon_SprT PF17283.2 EGD88010.1 - 3.5 7.6 6.0 5.3 7.0 0.5 2.2 1 1 1 2 2 2 0 SprT-like zinc ribbon domain TPR_2 PF07719.17 EGD88011.1 - 3.6e-28 95.4 11.4 0.001 19.0 0.3 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGD88011.1 - 9.6e-25 85.3 9.1 0.00036 20.2 0.8 10.3 11 0 0 11 11 11 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EGD88011.1 - 5.4e-23 81.0 21.8 1.4e-21 76.5 1.9 5.6 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGD88011.1 - 1.9e-16 60.3 12.9 0.0025 18.3 0.0 7.5 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGD88011.1 - 1.9e-15 55.7 10.9 0.013 15.7 0.1 9.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGD88011.1 - 7.8e-14 51.7 25.6 4.2e-08 33.4 0.3 10.0 8 3 2 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGD88011.1 - 9.4e-11 42.2 16.3 0.056 14.1 0.6 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGD88011.1 - 2.2e-10 40.5 15.8 1.9 9.5 0.4 8.4 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGD88011.1 - 8.1e-10 38.3 18.7 0.00012 21.8 0.1 7.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGD88011.1 - 4.8e-07 30.0 8.3 3.1 8.6 0.1 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGD88011.1 - 1.7e-06 27.6 22.7 0.93 9.7 0.1 9.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGD88011.1 - 7.1e-06 25.6 11.4 0.38 10.5 0.1 7.1 6 2 2 8 8 8 2 TPR repeat TPR_17 PF13431.6 EGD88011.1 - 0.00073 19.7 12.1 8 7.1 0.0 8.1 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_21 PF09976.9 EGD88011.1 - 0.0029 17.4 2.1 5.7 6.6 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 EGD88011.1 - 0.0062 16.6 0.2 0.65 10.0 0.0 3.6 3 0 0 3 3 3 1 Putative TPR-like repeat TPR_4 PF07721.14 EGD88011.1 - 0.011 16.3 9.9 0.22 12.2 0.4 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat Fungal_trans PF04082.18 EGD88012.1 - 1.5e-07 30.8 0.0 3.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD88012.1 - 1.9e-06 27.9 12.2 3.9e-06 26.9 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHHC PF01529.20 EGD88016.1 - 1.2e-26 93.4 2.7 1.2e-26 93.4 2.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Glyco_hydro_17 PF00332.18 EGD88019.1 - 1.8e-08 34.4 2.8 4.9e-05 23.1 1.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 TFIIA PF03153.13 EGD88020.1 - 0.0035 17.4 49.4 0.19 11.7 32.0 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EGD88020.1 - 0.29 9.3 45.5 0.72 8.0 22.7 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 MMR1 PF08505.10 EGD88020.1 - 0.53 10.5 23.0 0.1 12.8 9.5 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Macoilin PF09726.9 EGD88020.1 - 0.55 8.7 16.8 1.5 7.3 6.4 2.2 2 0 0 2 2 2 0 Macoilin family Spt20 PF12090.8 EGD88020.1 - 1.9 8.1 48.2 0.6 9.7 28.7 2.5 2 0 0 2 2 2 0 Spt20 family NST1 PF13945.6 EGD88020.1 - 2.6 8.1 25.1 1.4 8.9 12.8 2.6 2 0 0 2 2 2 0 Salt tolerance down-regulator CiPC PF15800.5 EGD88020.1 - 7.3 6.2 36.6 1.1 8.9 15.7 2.3 2 0 0 2 2 2 0 Clock interacting protein circadian SRR1 PF07985.12 EGD88021.2 - 9.3e-07 28.8 0.2 2.6e-06 27.4 0.2 1.8 1 1 0 1 1 1 1 SRR1 RRP7 PF12923.7 EGD88021.2 - 0.17 12.0 1.2 0.28 11.3 0.4 1.8 2 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Abhydrolase_1 PF00561.20 EGD88026.2 - 2.1e-16 60.3 0.1 2.7e-16 60.0 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD88026.2 - 7.9e-14 52.8 1.7 9.9e-14 52.5 1.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGD88026.2 - 1.3e-08 34.5 0.2 1.5e-08 34.2 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EGD88026.2 - 0.0016 17.5 0.0 0.0019 17.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EGD88026.2 - 0.0056 15.7 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.20 EGD88026.2 - 0.015 15.0 0.1 0.046 13.4 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 EGD88026.2 - 0.039 13.4 0.2 0.058 12.9 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family YhhN PF07947.14 EGD88028.1 - 2.6e-41 141.2 4.2 4.2e-41 140.6 4.2 1.3 1 1 0 1 1 1 1 YhhN family DUF1118 PF06549.12 EGD88028.1 - 5 7.5 5.8 9.1 6.6 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1118) MFS_1 PF07690.16 EGD88029.1 - 5e-46 157.2 27.3 5e-46 157.2 27.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD88029.1 - 8.3e-09 34.8 8.0 8.3e-09 34.8 8.0 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EGD88029.1 - 0.15 10.3 3.9 0.086 11.1 1.3 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CPP1-like PF11833.8 EGD88029.1 - 0.86 9.2 8.2 0.1 12.2 3.3 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like eIF-5a PF01287.20 EGD88030.2 - 4.9e-05 23.3 0.1 9.3e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold F-box-like_2 PF13013.6 EGD88031.1 - 0.017 15.1 0.1 0.026 14.5 0.1 1.6 1 1 0 1 1 1 0 F-box-like domain F-box-like_2 PF13013.6 EGD88032.1 - 0.012 15.6 0.4 0.042 13.8 0.4 1.9 1 1 0 1 1 1 0 F-box-like domain PHD PF00628.29 EGD88034.1 - 2.9e-10 39.9 1.7 6.9e-10 38.7 1.7 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGD88034.1 - 0.00034 20.1 2.3 0.00054 19.4 2.3 1.3 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 EGD88034.1 - 0.25 11.4 1.6 0.67 10.0 1.6 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger UIM PF02809.20 EGD88034.1 - 0.36 10.8 3.3 0.95 9.5 3.3 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Roughex PF06020.11 EGD88036.1 - 0.14 11.2 9.5 0.62 9.1 0.0 2.3 2 0 0 2 2 2 0 Drosophila roughex protein Otopetrin PF03189.13 EGD88036.1 - 0.88 8.3 2.9 1 8.1 0.0 2.0 2 0 0 2 2 2 0 Otopetrin TFIIA PF03153.13 EGD88036.1 - 1.4 8.8 36.2 0.025 14.6 24.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 EGD88036.1 - 3.4 6.9 8.1 6.2 6.1 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MARVEL PF01284.23 EGD88037.1 - 3.5e-10 40.1 4.0 5.8e-10 39.4 4.0 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF1752 PF08550.10 EGD88038.2 - 9.6e-11 41.3 3.5 2e-10 40.3 3.5 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) adh_short_C2 PF13561.6 EGD88039.1 - 3.4e-52 177.3 0.0 4.5e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD88039.1 - 1.2e-35 122.7 0.0 2e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD88039.1 - 1.5e-11 44.5 0.1 2.7e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGD88039.1 - 0.025 14.0 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase CPSase_L_D2 PF02786.17 EGD88040.1 - 8.7e-74 247.6 0.0 1.3e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EGD88040.1 - 2.2e-36 124.3 0.0 4.8e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EGD88040.1 - 2.3e-35 121.5 0.0 5e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EGD88040.1 - 6.9e-15 54.6 3.5 7.7e-15 54.5 2.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGD88040.1 - 1.9e-09 37.3 0.0 4.4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGD88040.1 - 2.2e-08 33.8 0.0 4.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EGD88040.1 - 1.3e-05 24.9 0.3 0.12 12.2 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EGD88040.1 - 0.00049 20.2 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EGD88040.1 - 0.0017 19.0 0.2 0.86 10.3 0.0 2.8 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.19 EGD88040.1 - 0.0027 17.5 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 EGD88040.1 - 0.0092 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 EGD88040.1 - 0.015 15.2 0.4 0.035 14.0 0.2 1.7 2 0 0 2 2 1 0 Glycine cleavage H-protein ATP-grasp_4 PF13535.6 EGD88040.1 - 0.019 14.5 0.0 0.069 12.7 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain HlyD_D23 PF16576.5 EGD88040.1 - 0.079 12.2 0.1 3.9 6.6 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 EGD88040.1 - 0.18 11.4 0.0 0.53 9.9 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Acyl-CoA_dh_1 PF00441.24 EGD88042.1 - 7.1e-40 136.7 0.4 1.3e-39 135.8 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGD88042.1 - 2.9e-35 121.3 0.1 5.9e-35 120.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGD88042.1 - 1.3e-26 92.6 0.1 2.6e-26 91.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGD88042.1 - 3.7e-15 56.4 0.0 6.6e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EGD88042.1 - 0.00018 21.3 0.3 0.00047 19.9 0.3 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.22 EGD88043.1 - 1.4e-139 466.0 0.0 1.7e-139 465.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EGD88043.1 - 0.034 13.6 0.0 8.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Ras PF00071.22 EGD88044.2 - 3.4e-27 95.0 0.0 3e-15 56.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Arf PF00025.21 EGD88044.2 - 1.7e-06 27.6 0.0 5.4e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGD88044.2 - 4.7e-06 26.8 0.0 0.00025 21.2 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EGD88044.2 - 0.001 19.3 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGD88044.2 - 0.003 17.5 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EGD88044.2 - 0.039 13.5 0.1 0.12 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 EGD88044.2 - 0.054 12.5 0.1 1.9 7.4 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 EGD88044.2 - 0.079 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Abhydrolase_1 PF00561.20 EGD88046.2 - 4.1e-20 72.5 0.1 4.1e-19 69.2 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 EGD88046.2 - 7e-05 22.6 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EGD88046.2 - 0.00091 18.6 0.0 0.092 12.0 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EGD88046.2 - 0.048 13.4 0.1 9.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.9 EGD88047.2 - 4.4e-24 84.5 3.7 6.1e-24 84.1 3.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 EGD88047.2 - 0.019 14.9 0.6 0.025 14.5 0.6 1.1 1 0 0 1 1 1 0 COBRA-like protein PAN_3 PF08277.12 EGD88047.2 - 0.063 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 PAN-like domain CX9C PF16860.5 EGD88047.2 - 0.2 11.7 5.1 0.097 12.7 1.7 2.2 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DDOST_48kD PF03345.14 EGD88048.1 - 2.9e-158 527.1 0.0 3.4e-158 526.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta NADHdh_A3 PF14987.6 EGD88049.1 - 0.023 15.0 0.2 0.03 14.6 0.2 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 GST_N_3 PF13417.6 EGD88052.2 - 1.4e-10 41.4 0.0 2.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGD88052.2 - 0.00012 22.3 0.0 0.00028 21.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGD88052.2 - 0.01 16.0 0.0 0.063 13.5 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGD88052.2 - 0.01 15.8 0.7 0.081 13.0 0.6 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGD88052.2 - 0.027 15.2 0.0 0.051 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF2306 PF10067.9 EGD88055.2 - 2.4e-14 53.8 6.1 2.4e-14 53.8 6.1 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 EGD88055.2 - 0.0043 17.3 0.7 0.0043 17.3 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF420) Sugar_tr PF00083.24 EGD88056.1 - 2.1e-81 274.1 21.5 2.5e-81 273.9 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGD88056.1 - 2.3e-30 105.7 37.8 1e-25 90.4 31.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.23 EGD88057.2 - 5.4e-79 265.7 28.5 8.8e-48 163.3 15.7 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EGD88057.2 - 2.8e-15 57.1 0.1 3.5e-14 53.5 0.1 2.4 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EGD88057.2 - 0.0025 17.5 0.2 0.0056 16.4 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGD88057.2 - 0.021 15.2 0.1 0.11 12.8 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGD88057.2 - 0.045 13.6 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 EGD88057.2 - 0.053 13.2 0.0 0.097 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 EGD88057.2 - 0.053 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain RepB-RCR_reg PF10723.9 EGD88057.2 - 0.19 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Replication regulatory protein RepB ADH_N PF08240.12 EGD88058.2 - 1.9e-22 79.2 9.2 2.2e-22 79.0 9.2 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Mito_carr PF00153.27 EGD88059.1 - 3.1e-40 136.0 8.8 4.2e-16 58.6 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ferric_reduct PF01794.19 EGD88060.2 - 6e-21 74.8 14.8 6e-21 74.8 14.8 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGD88060.2 - 3.8e-13 49.5 0.0 3.7e-12 46.3 0.0 2.4 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 EGD88060.2 - 1.6e-12 47.8 0.0 2.8e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.6 EGD88060.2 - 0.18 12.4 15.6 0.24 12.0 1.8 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Fun_ATP-synt_8 PF05933.13 EGD88060.2 - 0.48 10.6 4.8 0.39 10.9 2.0 2.4 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) ABC1 PF03109.16 EGD88061.1 - 5.6e-22 78.1 0.3 1.5e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EGD88061.1 - 0.081 12.8 1.0 0.27 11.1 0.5 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family IMS PF00817.20 EGD88062.1 - 6.4e-36 123.6 0.0 1.1e-33 116.3 0.0 2.3 1 1 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 EGD88062.1 - 2.9e-12 45.9 0.3 5.9e-12 45.0 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 EGD88062.1 - 1.7e-11 44.9 0.0 3.5e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain WSC PF01822.19 EGD88065.2 - 5.9e-08 32.8 10.1 5.9e-08 32.8 10.1 2.3 2 1 0 2 2 2 1 WSC domain TMEM154 PF15102.6 EGD88065.2 - 0.0001 22.2 0.2 0.0001 22.2 0.2 2.4 1 1 1 2 2 2 1 TMEM154 protein family Podoplanin PF05808.11 EGD88065.2 - 0.0099 16.0 10.1 0.019 15.0 10.1 1.4 1 0 0 1 1 1 1 Podoplanin FixQ PF05545.11 EGD88065.2 - 0.021 14.8 0.1 0.044 13.7 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Apt1 PF10351.9 EGD88065.2 - 0.46 9.3 10.4 0.64 8.8 10.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EGD88065.2 - 2.2 6.7 10.6 3 6.3 10.6 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 EGD88065.2 - 3.7 6.6 21.3 5.6 6.0 21.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 EGD88065.2 - 6.6 5.3 13.1 7.3 5.1 13.1 1.1 1 0 0 1 1 1 0 Hamartin protein Transp_cyt_pur PF02133.15 EGD88066.2 - 1.3e-24 86.8 34.9 1.3e-24 86.8 34.9 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PRP38 PF03371.15 EGD88068.1 - 1.4e-64 217.2 0.0 1.8e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 PRP38 family Tnp_22_trimer PF17489.2 EGD88068.1 - 0.25 11.3 3.0 0.52 10.3 3.0 1.4 1 0 0 1 1 1 0 L1 transposable element trimerization domain WD40 PF00400.32 EGD88070.1 - 6.4e-17 61.6 3.1 0.17 12.8 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Trypan_PARP PF05887.11 EGD88070.1 - 0.0043 17.0 4.4 0.0043 17.0 4.4 2.3 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) ANAPC4_WD40 PF12894.7 EGD88070.1 - 0.0052 17.0 0.0 8.4 6.8 0.0 3.8 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EGD88070.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain ABC_tran PF00005.27 EGD88072.1 - 2.4e-56 190.1 0.1 9.1e-31 107.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGD88072.1 - 1.3e-50 172.6 31.4 2.4e-33 116.0 14.5 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_23 PF13476.6 EGD88072.1 - 2.3e-07 31.5 0.5 0.00063 20.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EGD88072.1 - 2.5e-07 30.4 8.2 0.016 14.7 0.3 4.5 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGD88072.1 - 2.5e-06 27.5 1.6 0.053 13.3 0.0 3.4 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGD88072.1 - 6.3e-06 26.3 0.2 0.022 14.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGD88072.1 - 8e-06 25.8 0.1 0.15 11.9 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGD88072.1 - 0.00022 20.9 0.3 0.51 10.1 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 EGD88072.1 - 0.00079 19.6 1.2 0.025 14.7 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 EGD88072.1 - 0.0016 18.7 0.8 6.7 7.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EGD88072.1 - 0.002 17.7 0.0 0.19 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGD88072.1 - 0.0022 18.4 0.3 4 7.8 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain T2SSE PF00437.20 EGD88072.1 - 0.0024 17.0 0.2 0.028 13.5 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 EGD88072.1 - 0.014 15.9 0.3 3.2 8.2 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EGD88072.1 - 0.02 14.2 0.4 1.9 7.7 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 EGD88072.1 - 0.033 13.9 2.1 2.9 7.6 0.0 3.2 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_15 PF13175.6 EGD88072.1 - 0.037 13.7 0.1 0.83 9.3 0.0 2.5 3 0 0 3 3 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EGD88072.1 - 0.044 13.1 0.3 0.52 9.6 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 EGD88072.1 - 0.061 12.8 0.3 13 5.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EGD88072.1 - 0.098 13.2 0.1 14 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EGD88072.1 - 0.13 12.3 0.0 12 5.8 0.0 2.8 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 EGD88072.1 - 0.14 11.9 0.1 3.6 7.3 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase Adeno_IVa2 PF02456.15 EGD88072.1 - 0.19 10.5 0.3 0.72 8.6 0.1 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein TrwB_AAD_bind PF10412.9 EGD88072.1 - 0.22 10.4 2.2 2.3 7.1 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 EGD88072.1 - 0.38 10.3 2.5 0.93 9.1 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EGD88072.1 - 0.72 9.8 3.0 5.4 6.9 0.3 2.5 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 EGD88072.1 - 0.92 9.6 3.9 10 6.2 0.4 2.9 3 0 0 3 3 2 0 Dynamin family Peptidase_M36 PF02128.15 EGD88073.2 - 9.6e-156 518.6 0.2 1.2e-155 518.2 0.2 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGD88073.2 - 1.2e-16 60.3 2.9 1.2e-16 60.3 2.9 2.2 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EGD88073.2 - 0.00019 21.4 0.0 0.00055 19.8 0.0 1.8 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain UQ_con PF00179.26 EGD88074.1 - 1.2e-38 131.9 0.0 1.5e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGD88074.1 - 0.015 15.6 0.3 0.029 14.6 0.3 1.7 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 EGD88074.1 - 0.037 13.7 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Bax1-I PF01027.20 EGD88075.2 - 1.2e-54 185.3 28.6 1.5e-54 185.0 28.6 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.11 EGD88075.2 - 6.7 6.5 27.9 8.5 6.2 14.1 2.1 1 1 0 2 2 2 0 7TM diverse intracellular signalling Aa_trans PF01490.18 EGD88076.1 - 2.6e-94 316.2 16.8 3.9e-94 315.7 16.8 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.10 EGD88076.1 - 0.1 10.8 3.4 0.17 10.1 3.4 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2417 PF10329.9 EGD88076.1 - 1.2 8.5 11.6 5 6.5 0.2 4.1 4 0 0 4 4 4 0 Region of unknown function (DUF2417) Glyco_hydro_75 PF07335.11 EGD88078.1 - 4.6e-61 205.8 0.2 5.9e-61 205.5 0.2 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 EMC1_C PF07774.13 EGD88079.2 - 1.1e-77 260.6 0.0 2.1e-77 259.6 0.0 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ PF01011.21 EGD88079.2 - 0.036 14.0 0.1 18 5.5 0.0 3.1 2 0 0 2 2 2 0 PQQ enzyme repeat CRAL_TRIO PF00650.20 EGD88081.1 - 1.9e-24 86.2 0.0 2.7e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGD88081.1 - 4.9e-08 33.0 0.0 1.7e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SNase PF00565.17 EGD88082.1 - 4.9e-80 265.0 0.2 6.9e-26 90.8 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EGD88082.1 - 9e-25 87.1 0.0 3.2e-24 85.3 0.0 1.9 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EGD88082.1 - 4.8e-05 22.8 0.0 8.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 EGD88082.1 - 0.0065 16.9 0.7 0.035 14.6 0.2 2.7 3 0 0 3 3 3 1 Agenet domain DUF3297 PF11730.8 EGD88082.1 - 0.032 14.1 0.0 0.14 12.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) Fungal_trans PF04082.18 EGD88083.1 - 1.4e-25 89.8 0.2 3.2e-25 88.7 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD88083.1 - 2.1e-05 24.5 8.2 2.1e-05 24.5 8.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sod_Cu PF00080.20 EGD88084.2 - 4.9e-46 156.4 5.3 6.3e-46 156.1 5.3 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TAL_FSA PF00923.19 EGD88085.1 - 4.6e-95 318.2 0.1 5.2e-95 318.1 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 EGD88085.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Peptidase_S8 PF00082.22 EGD88087.1 - 3e-39 135.1 3.5 4.2e-39 134.6 3.5 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGD88087.1 - 3.3e-21 75.7 0.3 8e-21 74.5 0.3 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 EXS PF03124.14 EGD88088.2 - 2.8e-99 332.6 35.1 3.5e-99 332.3 35.1 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EGD88088.2 - 5.5e-60 204.3 7.4 5.5e-60 204.3 7.4 2.3 2 0 0 2 2 2 1 SPX domain BIRC6 PF12356.8 EGD88088.2 - 0.068 12.6 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 Emaravirus_P4 PF16505.5 EGD88088.2 - 0.077 12.0 0.4 0.13 11.3 0.4 1.2 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily Ribosom_S30AE_C PF16321.5 EGD88088.2 - 0.14 11.9 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus Abhydrolase_6 PF12697.7 EGD88089.2 - 0.00013 22.6 0.1 0.00029 21.5 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGD88089.2 - 0.0025 17.1 0.0 0.038 13.2 0.0 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 EGD88089.2 - 0.004 17.1 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EGD88089.2 - 0.0046 16.5 0.0 0.49 9.9 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EGD88089.2 - 0.0055 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1100 PF06500.11 EGD88089.2 - 0.0068 15.2 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Zn_clus PF00172.18 EGD88090.1 - 1.9e-09 37.5 10.5 3.4e-09 36.7 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGD88090.1 - 0.00072 18.5 1.2 0.00097 18.1 1.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_2 PF02230.16 EGD88091.1 - 2e-21 76.8 0.0 2.6e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGD88091.1 - 3.1e-06 28.0 0.3 4e-06 27.6 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family XylR_N PF06505.11 EGD88091.1 - 0.046 13.5 0.1 0.092 12.5 0.1 1.4 1 0 0 1 1 1 0 Activator of aromatic catabolism PDEase_I_N PF08499.12 EGD88092.2 - 0.083 12.7 0.2 0.39 10.6 0.1 2.2 1 1 1 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Metallophos PF00149.28 EGD88093.1 - 2.9e-37 129.1 0.6 7.3e-37 127.9 0.2 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 EGD88093.1 - 0.11 12.2 0.6 1.7 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) Voldacs PF03517.13 EGD88098.1 - 9.4e-30 103.5 1.4 9.4e-30 103.5 1.4 2.0 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Opi1 PF08618.10 EGD88102.1 - 1.6e-44 152.9 12.3 8.7e-33 114.2 5.0 3.1 1 1 2 3 3 3 3 Transcription factor Opi1 RdRP PF05183.12 EGD88103.2 - 4.8e-132 441.6 0.0 6.6e-132 441.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase AA_permease PF00324.21 EGD88104.1 - 6.2e-127 424.1 41.9 7.6e-127 423.8 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD88104.1 - 3.2e-36 125.1 41.9 4e-36 124.8 41.9 1.1 1 0 0 1 1 1 1 Amino acid permease Gtr1_RagA PF04670.12 EGD88106.2 - 1.7e-54 184.6 0.2 2.1e-54 184.3 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 EGD88106.2 - 0.088 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain zf-RanBP PF00641.18 EGD88108.1 - 1.9e-19 68.6 8.4 7.1e-10 38.0 1.5 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RNase_T PF00929.24 EGD88108.1 - 2.8e-07 31.2 0.0 4.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 EGD88108.1 - 8e-07 28.8 0.0 1.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cnd3 PF12719.7 EGD88110.2 - 2.3e-90 302.8 0.1 8.5e-90 300.9 0.0 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EGD88110.2 - 2.4e-05 24.6 1.6 0.0047 17.3 0.7 3.2 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 EGD88110.2 - 0.0013 19.2 1.4 0.29 11.7 0.1 4.2 3 0 0 3 3 3 1 HEAT-like repeat DUF3306 PF11748.8 EGD88110.2 - 0.38 11.6 0.0 0.38 11.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) HEAT PF02985.22 EGD88110.2 - 0.91 10.0 6.4 17 6.0 0.1 4.5 5 0 0 5 5 5 0 HEAT repeat RICTOR_N PF14664.6 EGD88110.2 - 1.7 7.5 5.1 1.3 8.0 0.1 2.6 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term PALP PF00291.25 EGD88111.1 - 1.3e-67 228.3 0.2 1.6e-67 228.0 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Oxidored_molyb PF00174.19 EGD88112.1 - 3.9e-59 199.1 0.0 5.8e-59 198.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGD88112.1 - 6.4e-26 91.0 0.9 1.3e-25 90.0 0.9 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.20 EGD88112.1 - 0.22 11.7 2.3 0.56 10.4 0.2 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat Tim17 PF02466.19 EGD88114.2 - 6e-39 132.8 5.6 9.4e-39 132.2 5.6 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 EGD88114.2 - 1.2 9.6 12.0 0.82 10.1 1.3 3.3 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 DUF4048 PF13257.6 EGD88116.1 - 4.4e-81 272.5 20.6 4.4e-81 272.5 20.6 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4048) SLATT_1 PF18181.1 EGD88116.1 - 0.055 13.4 0.5 0.11 12.4 0.5 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DBR1 PF05011.13 EGD88116.1 - 0.11 12.9 2.1 0.26 11.7 2.1 1.6 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain Bap31_Bap29_C PF18035.1 EGD88116.1 - 0.17 11.9 3.2 0.35 10.9 3.2 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain EVI2A PF05399.11 EGD88116.1 - 6.6 6.3 9.9 18 4.9 9.9 1.8 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) CAP59_mtransfer PF11735.8 EGD88117.1 - 1.4e-71 241.0 0.0 1.7e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Herpes_UL37_2 PF07413.11 EGD88117.1 - 0.16 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 UPF0262 PF06793.12 EGD88118.2 - 0.071 13.2 0.0 0.15 12.1 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0262) Prim-Pol PF09250.11 EGD88118.2 - 0.12 12.7 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal RicinB_lectin_2 PF14200.6 EGD88120.1 - 0.1 13.3 0.0 1.9 9.3 0.0 2.1 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Peptidase_C3 PF00548.20 EGD88120.1 - 0.22 11.4 0.4 5.8 6.8 0.0 2.1 2 0 0 2 2 2 0 3C cysteine protease (picornain 3C) Pkinase PF00069.25 EGD88122.1 - 1.4e-70 237.7 0.0 1.9e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD88122.1 - 6.8e-48 163.2 0.0 1e-47 162.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD88122.1 - 1.1e-05 24.4 0.0 3.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGD88122.1 - 0.00018 21.0 0.0 0.0032 16.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGD88122.1 - 0.035 14.0 0.1 6.5 6.6 0.0 2.8 3 1 1 4 4 4 0 Phosphotransferase enzyme family ABC1 PF03109.16 EGD88122.1 - 0.17 12.0 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 ABC1 family FAD-oxidase_C PF02913.19 EGD88123.2 - 3.2e-62 210.4 0.0 4.6e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGD88123.2 - 9.7e-36 122.6 0.4 1.9e-35 121.6 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.21 EGD88127.1 - 2.7e-52 177.8 0.0 1.5e-51 175.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Proteasome PF00227.26 EGD88129.1 - 1.4e-54 184.5 0.1 1.8e-54 184.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGD88129.1 - 6e-13 48.2 0.3 2.1e-12 46.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 EGD88129.1 - 0.065 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-CHY PF05495.12 EGD88130.2 - 1.3e-10 41.6 15.9 1.3e-10 41.6 15.9 1.7 2 0 0 2 2 2 1 CHY zinc finger Zn-ribbon_8 PF09723.10 EGD88130.2 - 2 8.6 13.8 5.9 7.1 6.6 2.5 1 1 1 2 2 2 0 Zinc ribbon domain ERG4_ERG24 PF01222.17 EGD88131.1 - 2e-148 494.7 9.3 2.3e-148 494.5 9.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGD88131.1 - 6.4e-05 22.6 0.1 0.00021 20.9 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ANAPC4_WD40 PF12894.7 EGD88132.2 - 0.098 13.0 0.0 9.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGD88132.2 - 0.12 12.9 1.7 23 5.7 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain FMO-like PF00743.19 EGD88133.2 - 3.6e-19 68.6 0.3 6e-17 61.3 0.1 2.9 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGD88133.2 - 3.2e-05 23.3 0.0 0.0097 15.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGD88133.2 - 0.0002 20.6 0.0 0.0022 17.2 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGD88133.2 - 0.00033 20.8 0.2 0.0013 19.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGD88133.2 - 0.0094 15.2 0.1 0.5 9.6 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGD88133.2 - 0.012 15.7 0.0 0.36 10.8 0.0 3.0 3 1 0 3 3 3 0 FAD-NAD(P)-binding GCR1_C PF12550.8 EGD88133.2 - 0.035 14.4 2.5 0.22 11.9 0.1 2.8 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes PRESAN PF09687.10 EGD88133.2 - 2.7 8.6 6.0 14 6.3 2.3 2.3 2 0 0 2 2 2 0 Plasmodium RESA N-terminal APH PF01636.23 EGD88134.1 - 1.2e-19 71.2 0.0 1.9e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD88134.1 - 3.3e-06 26.9 0.0 4.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EGD88134.1 - 2.5e-05 23.8 0.0 0.045 13.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 EGD88134.1 - 0.0005 19.7 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Fructosamin_kin PF03881.14 EGD88134.1 - 0.0022 17.2 0.3 0.17 11.1 0.0 2.6 2 1 1 3 3 3 1 Fructosamine kinase Kdo PF06293.14 EGD88134.1 - 0.0078 15.6 0.0 0.9 8.8 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EGD88134.1 - 0.025 13.9 0.0 2.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase DUF1679 PF07914.11 EGD88134.1 - 0.041 12.8 0.0 0.3 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) UPF0047 PF01894.17 EGD88136.2 - 2.1e-37 127.8 0.0 2.6e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 ECH_1 PF00378.20 EGD88138.2 - 2.7e-49 167.7 0.0 3.8e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGD88138.2 - 3.5e-22 79.3 0.0 6.6e-22 78.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase LPD15 PF18828.1 EGD88138.2 - 0.042 13.7 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 zf-CHCC PF10276.9 EGD88139.1 - 1.1e-15 57.4 3.1 1.8e-15 56.7 3.1 1.3 1 0 0 1 1 1 1 Zinc-finger domain ORC6 PF05460.13 EGD88140.2 - 0.079 12.2 3.1 0.079 12.2 3.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CoaE PF01121.20 EGD88141.1 - 2e-42 144.9 0.0 2.8e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EGD88141.1 - 0.004 17.7 0.0 0.058 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain 2TM PF13239.6 EGD88141.1 - 0.032 14.5 0.1 0.079 13.3 0.1 1.6 1 0 0 1 1 1 0 2TM domain AAA_33 PF13671.6 EGD88141.1 - 0.035 14.3 0.0 0.29 11.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain NUDIX_2 PF13869.6 EGD88142.1 - 2.3e-81 271.9 0.0 2.8e-81 271.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase SUKH-3 PF14433.6 EGD88142.1 - 0.13 12.7 0.0 0.46 10.9 0.0 1.9 1 1 0 1 1 1 0 SUKH-3 immunity protein APH PF01636.23 EGD88144.2 - 8.8e-14 52.0 0.0 1.7e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGD88144.2 - 0.058 12.2 0.1 0.66 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 EGD88144.2 - 0.14 11.3 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Peptidase_M16_M PF16187.5 EGD88145.2 - 6.6e-98 327.4 0.1 9.8e-98 326.9 0.1 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EGD88145.2 - 4.1e-35 121.4 0.1 7.5e-23 81.5 0.0 3.9 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGD88145.2 - 2.1e-32 112.1 2.6 5.8e-22 78.3 0.3 3.9 4 0 0 4 4 4 2 Insulinase (Peptidase family M16) DUF386 PF04074.12 EGD88146.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 YhcH/YjgK/YiaL DUF1258 PF06869.12 EGD88147.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) MFS_1 PF07690.16 EGD88148.1 - 2.9e-20 72.5 30.0 2.9e-20 72.5 30.0 2.8 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD88149.1 - 5.5e-125 417.8 23.2 6.3e-125 417.6 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGD88149.1 - 3.5e-21 75.5 37.3 9.9e-19 67.5 28.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGD88149.1 - 0.0072 14.8 5.4 0.034 12.6 0.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Gp_dh_C PF02800.20 EGD88151.1 - 4.3e-71 237.6 0.0 6.4e-71 237.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EGD88151.1 - 9.1e-38 128.7 0.2 2.3e-37 127.4 0.1 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EGD88151.1 - 0.0013 18.8 0.0 0.0077 16.3 0.0 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EGD88151.1 - 0.077 12.4 0.0 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EGD88151.1 - 0.086 13.7 0.0 6.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Pho88 PF10032.9 EGD88153.1 - 3.3e-77 257.9 0.5 3.8e-77 257.7 0.5 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4512 PF14975.6 EGD88153.1 - 0.14 13.0 0.4 0.51 11.2 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) Histone PF00125.24 EGD88154.1 - 7.6e-16 58.7 0.0 9.4e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGD88154.1 - 5.5e-12 45.2 0.0 9.3e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGD88154.1 - 0.00036 20.7 0.0 0.00052 20.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HSF_DNA-bind PF00447.17 EGD88155.1 - 2.5e-29 101.8 0.3 5.4e-29 100.7 0.3 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 EGD88155.1 - 0.047 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Ets-domain TMF_DNA_bd PF12329.8 EGD88155.1 - 0.11 12.4 1.5 0.36 10.9 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding NPCC PF08058.11 EGD88156.2 - 0.073 13.1 0.0 0.084 12.9 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex component UL11 PF11094.8 EGD88156.2 - 0.096 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Membrane-associated tegument protein R3H PF01424.22 EGD88158.2 - 5.9e-10 39.0 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 EGD88158.2 - 0.0099 15.7 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUIM_assoc PF16619.5 EGD88158.2 - 0.02 14.9 1.7 0.02 14.9 1.7 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CAS_C PF12026.8 EGD88158.2 - 2.8 8.0 5.6 0.34 11.0 1.7 1.4 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain Pro_isomerase PF00160.21 EGD88159.1 - 1.2e-37 129.6 0.0 2.7e-37 128.5 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ORC_WH_C PF18137.1 EGD88159.1 - 0.0066 16.5 1.0 0.0066 16.5 1.0 2.9 3 0 0 3 3 3 1 Origin recognition complex winged helix C-terminal His_Phos_2 PF00328.22 EGD88160.1 - 1.1e-08 34.9 0.0 3.9e-07 29.7 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Peptidase_M19 PF01244.21 EGD88161.1 - 4.9e-109 364.4 0.0 5.6e-109 364.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) AAA PF00004.29 EGD88162.1 - 1.3e-16 61.2 0.3 3.1e-16 60.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EGD88162.1 - 6.2e-16 58.6 0.1 3.3e-15 56.2 0.0 2.3 3 0 0 3 3 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EGD88162.1 - 1.7e-12 47.4 0.0 8.8e-12 45.1 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EGD88162.1 - 7.3e-09 35.8 0.0 1.3e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EGD88162.1 - 3e-08 33.9 0.1 1.7e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 AAA C-terminal domain AAA_30 PF13604.6 EGD88162.1 - 1.3e-06 28.3 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EGD88162.1 - 1.3e-06 28.3 0.0 2.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 EGD88162.1 - 3.3e-06 27.6 0.0 5.2e-05 23.7 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 EGD88162.1 - 5.1e-06 26.5 0.1 9.6e-06 25.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGD88162.1 - 1.5e-05 25.0 0.2 6.2e-05 23.0 0.1 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGD88162.1 - 1.8e-05 25.0 0.3 0.00015 22.0 0.1 2.4 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 EGD88162.1 - 9.6e-05 21.7 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EGD88162.1 - 0.00012 21.8 0.0 0.00033 20.5 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EGD88162.1 - 0.00027 20.7 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EGD88162.1 - 0.00029 20.7 0.0 0.00095 19.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EGD88162.1 - 0.00083 19.4 0.0 0.086 12.8 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGD88162.1 - 0.00095 19.5 0.0 0.0037 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGD88162.1 - 0.001 19.1 0.0 0.0028 17.7 0.0 1.7 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGD88162.1 - 0.0024 17.6 0.0 0.0063 16.2 0.0 1.6 2 0 0 2 2 1 1 Sigma-54 interaction domain PhoH PF02562.16 EGD88162.1 - 0.0031 17.0 0.2 0.61 9.5 0.0 2.3 1 1 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 EGD88162.1 - 0.0064 16.3 0.0 0.036 13.9 0.1 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.6 EGD88162.1 - 0.0075 16.8 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGD88162.1 - 0.014 15.6 0.0 0.034 14.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EGD88162.1 - 0.023 14.1 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EGD88162.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MiaE PF06175.11 EGD88162.1 - 0.039 13.6 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) Mg_chelatase PF01078.21 EGD88162.1 - 0.049 13.0 0.2 0.26 10.6 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EGD88162.1 - 0.056 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EGD88162.1 - 0.058 12.6 0.0 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EGD88162.1 - 0.07 13.5 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EGD88162.1 - 0.088 12.7 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Cullin_Nedd8 PF10557.9 EGD88162.1 - 0.11 12.5 0.2 20 5.3 0.0 3.2 3 0 0 3 3 3 0 Cullin protein neddylation domain P21-Arc PF04062.14 EGD88163.1 - 2.2e-75 252.5 0.0 2.5e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.18 EGD88163.1 - 0.066 13.3 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide NmrA PF05368.13 EGD88164.2 - 9.6e-07 28.6 0.1 5.8e-06 26.0 0.1 2.2 2 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EGD88164.2 - 3.5e-05 23.8 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Pallilysin PF18663.1 EGD88164.2 - 0.089 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Pallilysin beta barrel domain Pkinase PF00069.25 EGD88165.1 - 6.4e-20 71.6 0.0 1.6e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD88165.1 - 2.3e-06 27.1 0.0 0.0068 15.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGD88165.1 - 0.0091 15.9 0.2 0.047 13.6 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Peptidase_M35 PF02102.15 EGD88166.1 - 5.8e-101 337.9 13.7 6.5e-101 337.8 13.7 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EGD88166.1 - 1.4e-41 142.4 3.0 1.4e-41 142.4 3.0 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EGD88166.1 - 0.00093 18.8 3.1 0.0037 16.9 3.1 1.9 1 1 0 1 1 1 1 Putative peptidase family MINDY_DUB PF04424.13 EGD88167.1 - 2.1e-18 66.4 0.0 3.7e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase Gcd10p PF04189.13 EGD88168.2 - 2.6e-76 256.6 0.0 4.9e-72 242.6 0.0 2.0 1 1 1 2 2 2 2 Gcd10p family DUF4248 PF14053.6 EGD88170.1 - 0.065 13.3 0.0 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) CorA PF01544.18 EGD88171.2 - 2.7e-09 36.8 0.4 4.3e-09 36.1 0.3 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein FtsX PF02687.21 EGD88171.2 - 0.11 13.0 1.7 0.18 12.3 1.7 1.3 1 0 0 1 1 1 0 FtsX-like permease family NmrA PF05368.13 EGD88172.2 - 2.7e-58 197.3 0.1 3.4e-58 196.9 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGD88172.2 - 5.4e-20 72.1 0.0 7.6e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGD88172.2 - 5.4e-06 25.6 0.1 7.8e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGD88172.2 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Myb_DNA-binding PF00249.31 EGD88174.1 - 5.5e-17 61.7 0.0 8.4e-09 35.5 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGD88174.1 - 4.5e-06 26.8 0.3 0.043 14.1 0.1 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGD88174.1 - 3.1e-05 23.8 3.7 0.00028 20.7 0.0 3.3 3 0 0 3 3 3 1 Myb DNA-binding like DS PF01916.17 EGD88175.1 - 1.7e-129 431.2 0.0 2e-129 431.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Pkinase PF00069.25 EGD88177.2 - 2.5e-10 40.1 0.0 3.3e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD88177.2 - 1.5e-08 34.3 0.0 1.8e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGD88177.2 - 9.2e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGD88177.2 - 9.3e-05 22.1 0.1 0.00013 21.7 0.1 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGD88177.2 - 0.00015 21.8 0.9 0.0011 18.9 0.8 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGD88177.2 - 0.00063 19.1 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EGD88177.2 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 EGD88177.2 - 0.019 14.0 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EGD88177.2 - 0.086 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase zf-C3HC4_3 PF13920.6 EGD88179.2 - 1.8e-10 40.5 11.8 2.8e-10 39.9 11.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 EGD88179.2 - 6.8e-08 32.3 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MORN PF02493.20 EGD88179.2 - 1.8e-07 30.7 24.6 0.014 15.3 4.8 4.7 4 0 0 4 4 4 3 MORN repeat Prok-RING_4 PF14447.6 EGD88179.2 - 0.0052 16.6 10.6 0.01 15.7 10.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 USP7_ICP0_bdg PF12436.8 EGD88179.2 - 0.015 14.6 0.0 0.37 10.1 0.0 2.3 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 zf-RING_5 PF14634.6 EGD88179.2 - 0.34 10.9 12.4 0.62 10.1 12.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EGD88179.2 - 1.3 8.9 10.1 1.9 8.4 9.1 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF913 PF06025.12 EGD88179.2 - 1.8 7.4 5.9 2.2 7.2 0.3 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Pkinase PF00069.25 EGD88180.2 - 9.3e-17 61.3 0.0 1.9e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD88180.2 - 3.9e-08 32.9 0.0 8.9e-08 31.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 EGD88180.2 - 0.072 12.7 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGD88180.2 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EGD88180.2 - 0.22 10.2 0.1 0.47 9.2 0.1 1.3 1 1 0 1 1 1 0 Fungal protein kinase HsbA PF12296.8 EGD88182.1 - 9.1e-29 100.3 7.8 9.1e-29 100.3 6.4 1.7 1 1 0 1 1 1 1 Hydrophobic surface binding protein A MF_alpha_N PF05436.11 EGD88182.1 - 0.065 13.1 2.4 0.073 13.0 0.5 2.2 2 1 0 2 2 2 0 Mating factor alpha precursor N-terminus DUF3216 PF11505.8 EGD88182.1 - 0.096 12.9 0.1 0.6 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) PIG-P PF08510.12 EGD88183.2 - 6.2e-53 177.8 0.9 6.2e-53 177.8 0.9 1.8 2 0 0 2 2 2 1 PIG-P DPM2 PF07297.12 EGD88183.2 - 0.012 15.9 7.8 0.021 15.1 7.8 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) BUD22 PF09073.10 EGD88183.2 - 0.018 14.4 5.7 0.023 14.1 5.7 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EGD88183.2 - 0.043 13.2 3.0 0.052 13.0 3.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EGD88183.2 - 0.094 11.0 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 EGD88183.2 - 0.23 10.8 2.1 0.36 10.2 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Phage_holin_3_6 PF07332.11 EGD88183.2 - 0.27 11.3 0.1 0.42 10.7 0.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III XPA_C PF05181.12 EGD88184.2 - 1.6e-26 92.0 2.3 3.2e-26 91.1 2.3 1.5 1 0 0 1 1 1 1 XPA protein C-terminus ADD_DNMT3 PF17980.1 EGD88184.2 - 0.089 12.8 0.5 0.089 12.8 0.5 1.8 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 MAS20 PF02064.15 EGD88184.2 - 0.11 12.6 1.2 0.23 11.5 1.2 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor Ribosomal_L32e PF01655.18 EGD88184.2 - 0.18 12.3 2.3 0.25 11.8 0.4 2.0 2 0 0 2 2 2 0 Ribosomal protein L32 YhfH PF14149.6 EGD88184.2 - 0.47 10.5 10.1 0.58 10.2 0.2 2.6 3 0 0 3 3 3 0 YhfH-like protein OrfB_Zn_ribbon PF07282.11 EGD88184.2 - 1.4 8.9 5.3 29 4.7 0.1 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain XPA_N PF01286.18 EGD88184.2 - 7.5 6.7 13.6 2.2 8.4 8.2 2.5 2 1 0 2 2 2 0 XPA protein N-terminal WD40 PF00400.32 EGD88185.2 - 1.4e-24 85.9 22.9 1.7e-05 25.5 0.4 8.1 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD88185.2 - 5.2e-05 23.5 0.0 3.8 7.9 0.1 4.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGD88185.2 - 0.047 13.6 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A ADH_N_2 PF16884.5 EGD88185.2 - 0.11 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase PQQ PF01011.21 EGD88185.2 - 0.12 12.3 0.2 11 6.2 0.1 2.8 2 0 0 2 2 2 0 PQQ enzyme repeat Cytochrom_D1 PF02239.16 EGD88185.2 - 0.13 10.7 0.2 0.28 9.6 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain Blt1 PF12754.7 EGD88186.1 - 4.5e-47 160.1 1.9 5.8e-47 159.8 1.9 1.1 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 EGD88186.1 - 0.00055 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Get5 carboxyl domain DUF2340 PF10209.9 EGD88186.1 - 0.01 16.3 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) Methyltr_RsmB-F PF01189.17 EGD88187.1 - 2.1e-73 246.3 0.0 3.3e-73 245.6 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EGD88187.1 - 5e-07 30.1 0.0 1.4e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EGD88187.1 - 0.026 14.7 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4717 PF15838.5 EGD88187.1 - 0.19 11.8 3.0 0.5 10.4 3.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) PHO4 PF01384.20 EGD88188.2 - 0.0015 17.6 2.4 0.0017 17.5 2.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family EamA PF00892.20 EGD88188.2 - 0.017 15.3 5.2 0.022 14.9 5.2 1.2 1 0 0 1 1 1 0 EamA-like transporter family TPT PF03151.16 EGD88188.2 - 0.024 14.0 2.0 0.028 13.8 2.0 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family UAA PF08449.11 EGD88188.2 - 0.049 12.8 3.9 0.058 12.6 3.9 1.1 1 0 0 1 1 1 0 UAA transporter family DUF2431 PF10354.9 EGD88189.1 - 5.8e-60 202.4 0.0 1e-59 201.5 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) CLTH PF10607.9 EGD88190.2 - 1.7e-23 83.1 0.2 4.2e-23 81.9 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain DUF5398 PF17376.2 EGD88190.2 - 0.032 14.8 3.9 1.5 9.5 0.0 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5398) LisH PF08513.11 EGD88190.2 - 0.091 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 LisH COX16 PF14138.6 EGD88190.2 - 0.11 13.1 0.4 0.32 11.5 0.4 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF2570 PF10828.8 EGD88190.2 - 0.8 9.6 3.3 9.4 6.1 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) TPR_4 PF07721.14 EGD88190.2 - 1.6 9.5 4.1 71 4.5 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat DKCLD PF08068.12 EGD88191.1 - 1.1e-33 115.1 0.2 2.6e-32 110.7 0.3 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EGD88191.1 - 3.9e-23 81.4 1.5 7.1e-23 80.5 1.5 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EGD88191.1 - 6.3e-23 81.8 0.2 6e-20 72.1 0.2 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EGD88191.1 - 7.6e-21 73.9 1.3 1.5e-20 72.9 1.3 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EGD88191.1 - 0.0049 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain DUF4407 PF14362.6 EGD88191.1 - 1.7 8.0 11.9 3 7.1 11.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNA_polI_A34 PF08208.11 EGD88191.1 - 9.1 6.3 31.1 14 5.7 31.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DER1 PF04511.15 EGD88192.1 - 2.2e-25 89.7 4.5 2.6e-25 89.5 4.5 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 EGD88192.1 - 0.51 10.3 11.8 0.044 13.8 6.3 1.8 2 0 0 2 2 2 0 Rhomboid family Abhydrolase_3 PF07859.13 EGD88193.2 - 1.6e-43 149.0 0.0 1.4e-41 142.7 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EGD88193.2 - 3.6e-06 26.1 0.4 2.2e-05 23.6 0.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family MaoC_dehydratas PF01575.19 EGD88194.1 - 0.005 16.4 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain PDT PF00800.18 EGD88195.2 - 3.3e-58 196.5 0.0 4.4e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EGD88195.2 - 4.6e-06 26.3 0.0 1.7e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 ACT domain eRF1_2 PF03464.15 EGD88196.2 - 1.2e-46 158.3 0.0 2e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGD88196.2 - 5.8e-39 133.1 0.2 1.2e-38 132.1 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EGD88196.2 - 2.2e-21 76.2 0.0 3.3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EGD88196.2 - 5.3e-10 39.7 0.0 1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EGD88196.2 - 1.1e-08 35.5 0.1 1.6e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Pkinase PF00069.25 EGD88198.1 - 2.4e-06 27.1 0.0 3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Bmt2 PF11968.8 EGD88199.1 - 2.7e-89 298.8 0.0 3.3e-89 298.5 0.0 1.0 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 EGD88199.1 - 0.029 14.2 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L23eN PF03939.13 EGD88200.1 - 5e-27 93.9 8.8 5e-27 93.9 8.8 1.7 1 1 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EGD88200.1 - 4.3e-13 49.4 3.9 5.4e-13 49.1 0.3 2.2 2 1 0 2 2 2 1 Ribosomal protein L23 Linker_histone PF00538.19 EGD88200.1 - 0.43 11.0 3.2 0.34 11.3 0.3 2.1 2 0 0 2 2 2 0 linker histone H1 and H5 family Forkhead PF00250.18 EGD88201.1 - 8.1e-34 115.7 0.0 1.5e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain G10 PF01125.17 EGD88202.2 - 1.1e-67 226.3 4.6 1.3e-67 226.2 4.6 1.0 1 0 0 1 1 1 1 G10 protein AA_kinase PF00696.28 EGD88204.1 - 1.1e-42 146.3 0.1 1.8e-42 145.6 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 EGD88204.1 - 1.2e-13 50.6 1.2 1.5e-11 43.9 0.2 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EGD88204.1 - 8.2e-12 44.7 0.1 5.2e-09 35.7 0.1 2.9 3 0 0 3 3 3 2 ACT domain Peptidase_C78 PF07910.13 EGD88206.2 - 2.1e-32 112.3 0.1 3.1e-32 111.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 EGD88206.2 - 0.00042 20.6 3.5 0.038 14.3 1.0 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 EGD88206.2 - 0.00067 19.2 0.1 0.0016 18.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 EGD88206.2 - 0.12 12.1 0.5 0.29 10.9 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EGD88206.2 - 0.35 11.4 2.5 4.5 7.9 0.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD88206.2 - 0.49 11.4 3.8 4 8.5 1.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger AAA_18 PF13238.6 EGD88207.1 - 3.2e-26 92.4 0.0 5.2e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGD88207.1 - 4.4e-08 33.6 0.0 1.1e-07 32.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EGD88207.1 - 0.00035 21.0 0.0 0.00067 20.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGD88207.1 - 0.0018 18.5 0.4 0.0029 17.8 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGD88207.1 - 0.002 18.3 0.1 0.033 14.4 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGD88207.1 - 0.0021 18.5 0.2 0.015 15.7 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGD88207.1 - 0.0025 18.1 0.0 0.0051 17.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGD88207.1 - 0.0033 17.4 0.0 0.0075 16.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 EGD88207.1 - 0.005 17.0 0.0 0.017 15.2 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase NTPase_1 PF03266.15 EGD88207.1 - 0.0053 16.7 0.1 0.015 15.2 0.0 1.7 2 0 0 2 2 2 1 NTPase KTI12 PF08433.10 EGD88207.1 - 0.0072 15.8 0.0 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Hydin_ADK PF17213.3 EGD88207.1 - 0.016 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RNA_helicase PF00910.22 EGD88207.1 - 0.039 14.3 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 EGD88207.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 EGD88207.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGD88207.1 - 0.18 11.3 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 EGD88207.1 - 0.23 11.8 0.5 0.27 11.5 0.5 1.5 1 1 0 1 1 1 0 AAA domain Ham1p_like PF01725.16 EGD88208.1 - 4.1e-57 193.1 0.0 4.6e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Myosin_head PF00063.21 EGD88209.2 - 3.3e-230 765.9 1.9 4.7e-230 765.4 1.9 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EGD88209.2 - 2.8e-26 91.8 2.6 2.8e-26 91.8 2.6 3.3 3 1 1 4 4 4 1 DIL domain IQ PF00612.27 EGD88209.2 - 4.1e-12 44.7 31.9 3.3e-05 23.3 0.6 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif GAS PF13851.6 EGD88209.2 - 0.00082 18.8 15.0 0.00082 18.8 15.0 2.8 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EGD88209.2 - 0.0031 16.4 20.7 0.0034 16.3 18.9 1.9 1 1 0 1 1 1 1 Spc7 kinetochore protein AAA_22 PF13401.6 EGD88209.2 - 0.0085 16.4 0.1 0.0085 16.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGD88209.2 - 0.0095 16.3 0.0 0.04 14.3 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain EzrA PF06160.12 EGD88209.2 - 0.043 12.0 15.9 1.3 7.1 15.1 2.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA RNA_helicase PF00910.22 EGD88209.2 - 0.08 13.3 0.0 0.32 11.4 0.0 2.1 2 0 0 2 2 1 0 RNA helicase CALCOCO1 PF07888.11 EGD88209.2 - 0.17 10.7 21.9 0.073 11.9 19.5 1.5 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.15 EGD88209.2 - 0.24 11.8 19.3 1.3 9.4 19.2 2.2 1 1 0 1 1 1 0 Fez1 KASH_CCD PF14662.6 EGD88209.2 - 0.81 9.5 24.0 0.26 11.1 19.2 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 EGD88209.2 - 1.2 9.3 25.3 0.068 13.2 3.3 3.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DegQ PF08181.11 EGD88209.2 - 1.3 9.2 9.1 0.062 13.4 1.4 2.7 2 0 0 2 2 2 0 DegQ (SacQ) family FlaC_arch PF05377.11 EGD88209.2 - 1.4 9.4 11.0 1.2 9.6 0.1 4.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 EGD88209.2 - 1.7 8.6 11.8 0.45 10.6 5.7 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4665 PF15679.5 EGD88209.2 - 9.2 7.0 7.4 1.4 9.6 1.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) NAP PF00956.18 EGD88210.2 - 6e-99 330.6 7.7 6e-99 330.6 7.7 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF2457 PF10446.9 EGD88210.2 - 9.8 5.2 30.4 2 7.5 20.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) P5-ATPase PF12409.8 EGD88211.2 - 1.8e-40 137.9 0.0 4e-40 136.8 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 EGD88211.2 - 8e-31 107.0 0.0 1.5e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGD88211.2 - 1.9e-15 57.8 0.0 1.3e-06 28.8 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EGD88211.2 - 2e-05 24.4 0.3 0.0029 17.3 0.0 2.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EGD88211.2 - 0.00052 19.6 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGD88211.2 - 0.00054 20.0 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGD88211.2 - 0.041 13.6 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3552 PF12072.8 EGD88218.2 - 0.0014 18.1 12.1 0.0016 17.9 12.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF2924 PF11149.8 EGD88218.2 - 0.041 14.3 1.9 0.041 14.3 1.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) 2-Hacid_dh_C PF02826.19 EGD88220.1 - 2.8e-49 166.9 0.0 4.5e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGD88220.1 - 2.2e-34 118.0 0.0 3.1e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 EGD88220.1 - 7.4e-05 22.4 0.2 0.00021 21.0 0.1 1.8 2 0 0 2 2 2 1 ACT domain NAD_binding_2 PF03446.15 EGD88220.1 - 0.00014 22.1 0.4 0.00036 20.7 0.4 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EGD88220.1 - 0.0084 16.2 0.1 0.018 15.1 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 EGD88220.1 - 0.015 15.8 0.1 0.055 14.0 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain IlvN PF07991.12 EGD88220.1 - 0.015 14.9 0.1 0.041 13.4 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF1780 PF08682.10 EGD88220.1 - 0.046 13.4 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) 3HCDH_N PF02737.18 EGD88220.1 - 0.15 11.9 1.5 2.3 8.1 0.5 2.7 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA-synt_2b PF00587.25 EGD88221.1 - 3.1e-34 118.5 0.0 5.2e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGD88221.1 - 1.2e-19 70.5 4.4 1.2e-19 70.5 4.4 1.9 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain DUF3698 PF12479.8 EGD88221.1 - 0.052 14.1 0.2 0.24 12.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3698) CAMSAP_CC1 PF17095.5 EGD88221.1 - 0.12 12.2 2.5 0.27 11.1 2.5 1.5 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin DUF4337 PF14235.6 EGD88221.1 - 2.1 8.4 4.3 4.2 7.5 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ras PF00071.22 EGD88222.1 - 4.3e-47 159.7 0.2 4.9e-47 159.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD88222.1 - 5.2e-17 62.2 0.1 7.5e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD88222.1 - 3.5e-07 29.8 0.0 3.8e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGD88222.1 - 1.4e-05 24.8 0.2 0.00027 20.5 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGD88222.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGD88222.1 - 0.0011 18.9 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGD88222.1 - 0.0016 17.9 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EGD88222.1 - 0.011 15.3 0.2 0.02 14.4 0.1 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3568 PF12092.8 EGD88222.1 - 0.06 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) AAA_14 PF13173.6 EGD88222.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EGD88222.1 - 0.14 11.7 0.1 0.43 10.1 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B WAPL PF07814.13 EGD88225.1 - 1.7e-77 260.7 6.5 2.7e-77 260.0 6.5 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.6 EGD88226.2 - 3.3e-74 248.8 0.0 2.1e-46 158.0 0.0 2.0 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase GTP_CH_N PF12471.8 EGD88228.2 - 4.9e-91 303.7 0.0 6.9e-91 303.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EGD88228.2 - 1.6e-17 63.6 0.0 2.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Ribosomal_S3Ae PF01015.18 EGD88229.1 - 6.7e-85 283.8 5.0 8.3e-85 283.5 5.0 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EGD88229.1 - 0.011 16.2 0.4 0.064 13.8 0.2 2.2 1 1 1 2 2 2 0 Translation initiation factor SUI1 LPD1 PF18796.1 EGD88229.1 - 0.13 12.4 0.1 0.51 10.5 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 1 TipAS PF07739.13 EGD88229.1 - 0.15 12.6 0.0 1.4 9.5 0.0 2.1 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Abhydrolase_6 PF12697.7 EGD88230.2 - 1.3e-07 32.5 0.0 1.7e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGD88230.2 - 4.1e-06 26.6 0.0 4.9e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD88230.2 - 5.4e-05 22.6 0.0 7.1e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Fungal_trans_2 PF11951.8 EGD88232.2 - 0.00016 20.7 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SLED PF12140.8 EGD88232.2 - 0.049 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 SLED domain RTA1 PF04479.13 EGD88233.1 - 1.2e-51 175.3 2.3 2e-51 174.6 2.3 1.4 1 0 0 1 1 1 1 RTA1 like protein Ribonuclease_3 PF00636.26 EGD88234.1 - 3.7e-14 53.2 0.1 2.9e-13 50.3 0.0 2.6 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGD88234.1 - 7.4e-11 42.3 0.0 1.5e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 EGD88234.1 - 0.16 12.7 0.1 0.16 12.7 0.1 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding motif Pannexin_like PF12534.8 EGD88234.1 - 0.82 8.7 2.9 1.3 8.0 2.9 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 MRP-S33 PF08293.11 EGD88235.2 - 8.6e-27 93.2 0.2 1e-26 92.9 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF382 PF04037.13 EGD88236.2 - 2.7e-59 198.9 1.4 2.7e-59 198.9 1.4 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 EGD88236.2 - 2.3e-20 72.2 3.7 5.3e-20 71.0 3.7 1.7 1 0 0 1 1 1 1 PSP ER_lumen_recept PF00810.18 EGD88238.1 - 1.3e-54 185.0 7.2 1.3e-54 185.0 7.2 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EGD88238.1 - 1.1 9.1 16.0 0.75 9.6 0.2 4.4 4 1 1 5 5 5 0 PQ loop repeat DUF485 PF04341.12 EGD88238.1 - 1.2 9.1 7.0 0.2 11.6 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function, DUF485 Integrase_H2C2 PF17921.1 EGD88239.2 - 1.5e-07 31.4 0.8 1.5e-07 31.4 0.8 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain XRCC4 PF06632.12 EGD88241.1 - 6.1e-10 38.5 13.8 1.1e-09 37.7 13.8 1.4 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.8 EGD88241.1 - 0.0017 18.5 1.7 0.004 17.3 1.7 1.6 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain Baculo_gp64 PF03273.13 EGD88241.1 - 0.032 13.0 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family GTP-bdg_M PF16360.5 EGD88241.1 - 0.033 14.8 1.7 7.4 7.3 0.9 2.5 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region ssDNA_DBD PF18333.1 EGD88241.1 - 0.11 12.7 1.0 0.19 11.8 1.0 1.5 1 0 0 1 1 1 0 Non-canonical single-stranded DNA-binding domain ZapB PF06005.12 EGD88241.1 - 1 9.9 6.5 0.67 10.4 4.2 2.0 2 0 0 2 2 2 0 Cell division protein ZapB SKA1 PF07160.12 EGD88241.1 - 5.4 6.8 11.7 0.48 10.2 6.3 1.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DivIC PF04977.15 EGD88241.1 - 8.2 6.3 7.3 1.5 8.6 1.5 2.4 2 0 0 2 2 2 0 Septum formation initiator Molybdopterin PF00384.22 EGD88242.1 - 2.4e-69 234.3 0.0 7.1e-68 229.5 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EGD88242.1 - 5.7e-19 67.9 0.2 1.5e-18 66.6 0.2 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 EGD88242.1 - 9.8e-19 67.8 0.0 2.6e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 EGD88242.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EGD88242.1 - 5.3e-08 32.7 0.6 5.3e-08 32.7 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 EGD88242.1 - 0.12 12.2 1.1 3.5 7.6 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 EGD88242.1 - 0.24 11.5 2.0 4.8 7.3 2.0 2.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster TPT PF03151.16 EGD88243.1 - 4.4e-58 196.9 17.1 5.4e-58 196.6 17.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family PSII PF00421.19 EGD88243.1 - 5e-06 25.5 0.1 8.8e-06 24.7 0.1 1.3 1 0 0 1 1 1 1 Photosystem II protein EamA PF00892.20 EGD88243.1 - 3.7e-05 23.9 35.5 0.00085 19.5 12.4 2.9 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGD88243.1 - 0.0016 17.8 15.2 0.05 12.8 6.2 2.2 2 0 0 2 2 2 2 UAA transporter family Peptidase_S9 PF00326.21 EGD88244.2 - 0.00017 21.2 0.1 0.00032 20.2 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF5627 PF18620.1 EGD88244.2 - 0.023 14.6 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5627) FliJ PF02050.16 EGD88245.2 - 3.8 7.7 9.9 8.9 6.6 2.0 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DUF5572 PF17733.1 EGD88246.1 - 5.1e-25 87.1 0.2 1e-24 86.1 0.2 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Ssl1 PF04056.14 EGD88247.1 - 1.2e-73 247.0 0.0 1.7e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EGD88247.1 - 1.1e-18 67.2 8.6 1.1e-18 67.2 8.6 2.4 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EGD88247.1 - 4.6e-15 56.2 0.0 1e-14 55.0 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Tfb4 PF03850.14 EGD88247.1 - 0.00077 19.0 3.8 0.00077 19.0 3.8 2.0 2 0 0 2 2 2 1 Transcription factor Tfb4 DZR PF12773.7 EGD88247.1 - 0.15 12.1 19.0 2.1 8.5 5.7 2.9 2 1 0 2 2 2 0 Double zinc ribbon YL1 PF05764.13 EGD88247.1 - 0.81 9.8 9.4 1.1 9.3 9.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF4796 PF16044.5 EGD88247.1 - 1.7 8.2 13.6 0.23 11.0 4.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) CDC45 PF02724.14 EGD88247.1 - 8.9 4.5 6.8 11 4.1 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein EIIBC-GUT_N PF03612.14 EGD88251.1 - 0.15 11.8 2.8 0.23 11.2 2.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Mito_carr PF00153.27 EGD88252.1 - 3e-56 187.3 1.9 2.8e-18 65.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EGD88252.1 - 0.043 14.0 0.0 5.4 7.3 0.0 3.5 4 1 0 4 4 4 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Arteri_Gl PF00951.18 EGD88252.1 - 0.11 12.4 0.3 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF3278 PF11683.8 EGD88252.1 - 0.11 12.6 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) TadE PF07811.12 EGD88252.1 - 0.65 10.3 4.0 3.3 8.1 0.3 2.7 2 0 0 2 2 2 0 TadE-like protein WD40 PF00400.32 EGD88253.1 - 0.0024 18.7 15.8 0.22 12.5 0.0 6.5 7 0 0 7 7 7 2 WD domain, G-beta repeat Nup160 PF11715.8 EGD88253.1 - 0.067 11.8 1.1 0.12 10.9 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Fibrillarin PF01269.17 EGD88253.1 - 0.14 11.3 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin UPF0029 PF01205.19 EGD88254.1 - 6.8e-29 100.3 0.1 1.1e-28 99.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EGD88254.1 - 0.00014 22.1 0.0 0.00038 20.7 0.0 1.7 1 1 1 2 2 2 1 RWD domain DUF2570 PF10828.8 EGD88254.1 - 0.0076 16.0 0.2 0.017 15.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) DUF4113 PF13438.6 EGD88254.1 - 0.0087 16.1 0.0 0.035 14.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4113) Glyco_hydro_61 PF03443.14 EGD88256.1 - 4e-05 23.6 0.0 7.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ribos_L4_asso_C PF14374.6 EGD88258.2 - 2.9e-30 104.1 0.8 5.4e-30 103.3 0.3 1.7 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribosomal_L4 PF00573.22 EGD88258.2 - 5.1e-25 88.3 0.1 7.4e-25 87.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DSPc PF00782.20 EGD88259.2 - 1.4e-22 79.9 0.0 1.7e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGD88259.2 - 0.002 18.4 0.0 0.0027 18.0 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain SIS_2 PF13580.6 EGD88259.2 - 0.0073 16.3 0.0 0.018 15.0 0.0 1.6 2 0 0 2 2 2 1 SIS domain Y_phosphatase PF00102.27 EGD88259.2 - 0.015 14.9 0.0 0.089 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGD88259.2 - 0.038 14.1 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate BCS1_N PF08740.11 EGD88261.1 - 1.5e-40 139.2 2.7 3e-40 138.2 2.7 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGD88261.1 - 2.6e-17 63.5 0.0 5.1e-15 56.1 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGD88261.1 - 0.0086 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGD88261.1 - 0.017 15.5 0.2 0.078 13.4 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain CCDC53 PF10152.9 EGD88261.1 - 0.035 14.5 3.1 0.065 13.7 0.8 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex ATPase PF06745.13 EGD88261.1 - 0.041 13.2 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 EGD88261.1 - 0.056 13.4 0.0 0.27 11.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NAAA-beta PF15508.6 EGD88262.1 - 8e-12 45.3 0.1 1.7e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF3395 PF11875.8 EGD88263.2 - 3.9e-39 134.1 0.0 6.1e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) RicinB_lectin_2 PF14200.6 EGD88264.2 - 0.058 14.1 0.0 12 6.7 0.1 2.4 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like SKIP_SNW PF02731.15 EGD88265.2 - 8.2e-72 240.1 5.7 8.2e-72 240.1 5.7 2.4 3 0 0 3 3 3 1 SKIP/SNW domain Borrelia_P83 PF05262.11 EGD88265.2 - 6 5.2 14.9 12 4.2 14.9 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein WD40 PF00400.32 EGD88266.2 - 1.8e-31 107.7 18.3 5.1e-09 36.6 0.7 8.4 8 0 0 8 8 8 5 WD domain, G-beta repeat Utp12 PF04003.12 EGD88266.2 - 1.7e-27 95.8 0.0 2.7e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EGD88266.2 - 3.6e-15 56.0 0.0 0.0032 17.7 0.0 6.3 2 1 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGD88266.2 - 9.5e-11 41.2 0.9 0.15 11.0 0.0 4.9 3 2 2 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGD88266.2 - 1e-06 27.7 1.5 0.4 9.3 0.0 4.2 2 2 2 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.12 EGD88266.2 - 0.011 15.6 0.2 20 5.3 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Pox_T4_N PF04491.12 EGD88266.2 - 0.022 14.6 0.4 0.16 11.8 0.1 2.3 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus Hemagglutinin PF00509.18 EGD88266.2 - 0.079 11.3 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin WD40_like PF17005.5 EGD88266.2 - 0.083 12.2 0.0 1.9 7.7 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain PQQ_3 PF13570.6 EGD88266.2 - 0.26 11.8 3.9 40 4.9 0.0 4.4 5 0 0 5 5 5 0 PQQ-like domain Septin PF00735.18 EGD88267.2 - 1.6e-112 375.4 0.3 2.4e-112 374.8 0.3 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGD88267.2 - 1.5e-07 31.5 0.0 3.3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGD88267.2 - 3.4e-06 26.7 1.4 0.00018 21.1 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGD88267.2 - 4.6e-06 26.6 0.1 6.1e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EGD88267.2 - 0.0023 18.2 0.3 0.0081 16.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 EGD88267.2 - 0.0031 17.0 0.1 0.0055 16.2 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 EGD88267.2 - 0.0065 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EGD88267.2 - 0.0065 15.8 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 EGD88267.2 - 0.0097 15.0 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 EGD88267.2 - 0.017 14.8 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGD88267.2 - 0.039 14.3 0.8 0.089 13.2 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 EGD88267.2 - 0.041 13.1 0.0 0.053 12.8 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain Ras PF00071.22 EGD88267.2 - 0.042 13.4 0.1 0.11 12.0 0.1 1.8 1 0 0 1 1 1 0 Ras family T2SSE PF00437.20 EGD88267.2 - 0.047 12.7 0.3 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein FOXP-CC PF16159.5 EGD88267.2 - 0.051 14.2 0.9 0.051 14.2 0.9 2.0 2 0 0 2 2 1 0 FOXP coiled-coil domain AAA_25 PF13481.6 EGD88267.2 - 0.054 13.1 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGD88267.2 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.23 EGD88267.2 - 0.088 12.9 3.0 6.5 6.8 0.0 3.1 2 1 1 3 3 3 0 Dynamin family ABC_tran PF00005.27 EGD88267.2 - 0.096 13.2 0.0 0.32 11.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 EGD88267.2 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 EGD88267.2 - 0.2 11.4 0.4 5.8 6.6 0.4 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PQQ PF01011.21 EGD88268.2 - 1.5e-07 31.0 0.1 0.0063 16.4 0.0 3.3 3 0 0 3 3 3 2 PQQ enzyme repeat ANAPC4_WD40 PF12894.7 EGD88268.2 - 2.7e-06 27.6 0.0 0.0069 16.7 0.0 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGD88268.2 - 0.004 18.0 1.4 0.99 10.4 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat VID27 PF08553.10 EGD88268.2 - 0.03 13.4 0.0 0.065 12.3 0.0 1.5 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 EGD88268.2 - 0.16 10.9 0.4 0.46 9.4 0.0 1.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ACT_7 PF13840.6 EGD88269.2 - 2.5e-26 91.2 0.1 4.3e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 ACT domain XRN_M PF17846.1 EGD88270.1 - 2.2e-98 330.1 3.1 4.5e-98 329.1 3.1 1.4 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EGD88270.1 - 8.4e-98 326.6 0.0 1.3e-97 326.0 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EGD88270.1 - 3.7e-73 245.4 2.8 5.6e-73 244.8 0.1 2.2 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 EGD88270.1 - 4.3e-33 113.4 0.0 1.1e-32 112.0 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EGD88270.1 - 4.3e-23 81.2 0.1 1.2e-22 79.8 0.1 1.8 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EGD88270.1 - 1.1e-09 38.2 0.5 2.7e-09 37.0 0.5 1.7 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 DUF2207 PF09972.9 EGD88270.1 - 0.078 11.7 0.8 0.15 10.8 0.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cwf_Cwc_15 PF04889.12 EGD88270.1 - 1.3 8.7 7.2 2.5 7.8 7.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAF1C_H4-bd PF12265.8 EGD88271.2 - 2e-29 101.7 0.3 1.3e-28 99.0 0.4 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGD88271.2 - 5.4e-28 96.7 8.2 3.1e-05 24.6 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD88271.2 - 1.6e-06 28.3 1.2 0.13 12.5 0.1 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain GTP_cyclohydroI PF01227.22 EGD88272.1 - 3.1e-73 245.0 0.3 4.4e-73 244.5 0.3 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EGD88272.1 - 0.0013 18.8 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Cu_amine_oxidN2 PF02727.16 EGD88272.1 - 0.092 13.0 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Questin_oxidase PF14027.6 EGD88274.1 - 4.8e-98 328.8 0.2 5.9e-98 328.5 0.2 1.1 1 0 0 1 1 1 1 Questin oxidase-like Thymidylate_kin PF02223.17 EGD88274.1 - 0.004 16.9 0.0 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 Thymidylate kinase Lactamase_B_5 PF14597.6 EGD88274.1 - 0.0067 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Pkinase PF00069.25 EGD88276.1 - 3.2e-70 236.5 0.0 4.7e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD88276.1 - 1.5e-32 112.9 0.0 2.8e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGD88276.1 - 0.00045 19.6 0.6 0.00099 18.5 0.6 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGD88276.1 - 0.0012 18.3 0.2 0.005 16.2 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGD88276.1 - 0.031 13.1 0.1 0.031 13.1 0.1 2.4 4 0 0 4 4 4 0 Fungal protein kinase Haspin_kinase PF12330.8 EGD88276.1 - 0.07 12.1 0.1 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain NUDIX PF00293.28 EGD88277.1 - 1.6e-16 60.5 0.0 3.4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 EGD88277.1 - 5.4e-16 59.1 0.0 3.9e-15 56.4 0.0 2.3 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EGD88277.1 - 2.6e-06 27.0 1.2 4.2e-06 26.3 1.2 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain MPM1 PF17234.2 EGD88278.1 - 0.56 10.5 6.0 1.4 9.2 6.0 1.8 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Dynamin_N PF00350.23 EGD88279.1 - 3.2e-20 72.9 0.0 7.1e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGD88279.1 - 1.8e-14 53.6 0.1 6e-14 51.9 0.1 1.9 1 1 0 1 1 1 1 Dynamin central region FeoB_N PF02421.18 EGD88279.1 - 4.7e-05 23.0 0.4 0.029 13.9 0.1 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGD88279.1 - 0.00023 21.2 0.0 0.0014 18.7 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.18 EGD88279.1 - 0.011 15.8 0.8 0.054 13.6 0.1 2.4 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_15 PF13175.6 EGD88279.1 - 0.013 15.2 0.2 0.28 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EGD88279.1 - 0.015 15.8 0.1 0.39 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain EF-G-binding_N PF07299.11 EGD88279.1 - 0.064 13.8 0.4 0.28 11.7 0.4 2.2 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal TetR_C_16 PF17920.1 EGD88279.1 - 0.096 12.9 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ERCC3_RAD25_C PF16203.5 EGD88280.2 - 6.7e-123 408.7 0.7 1.1e-122 407.9 0.7 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EGD88280.2 - 1.1e-14 54.8 0.0 2.5e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGD88280.2 - 4.8e-14 52.6 0.1 1.1e-13 51.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EGD88280.2 - 2.2e-07 29.9 0.0 3.1e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_34 PF13872.6 EGD88280.2 - 0.00061 18.8 0.0 0.001 18.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF4677 PF15726.5 EGD88280.2 - 0.12 12.5 0.6 0.24 11.6 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) DUF4748 PF15932.5 EGD88281.2 - 2.8e-23 81.4 0.9 9.1e-23 79.8 0.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) DUF3669 PF12417.8 EGD88283.1 - 7.3e-19 67.7 0.0 1.6e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Zinc finger protein DUF3669 PF12417.8 EGD88284.2 - 2e-17 63.2 0.5 1.1e-16 60.7 0.0 2.2 2 0 0 2 2 2 1 Zinc finger protein E1_dh PF00676.20 EGD88284.2 - 0.21 10.5 0.0 0.39 9.6 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component EMP24_GP25L PF01105.24 EGD88287.2 - 5.8e-46 156.7 0.1 6.7e-46 156.5 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD IrmA PF18673.1 EGD88287.2 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 interleukin receptor mimic protein A USP7_ICP0_bdg PF12436.8 EGD88288.2 - 2.4e-86 289.0 0.0 5.1e-85 284.6 0.0 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EGD88288.2 - 7.5e-72 241.3 1.1 3.9e-71 239.0 0.8 2.1 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EGD88288.2 - 6.5e-25 88.1 0.1 1.2e-24 87.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGD88288.2 - 1.4e-09 38.0 0.0 2.3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rad60-SLD PF11976.8 EGD88288.2 - 0.05 13.4 1.2 3.3 7.6 0.0 3.8 4 0 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGD88288.2 - 0.069 12.9 0.0 31 4.4 0.0 3.9 4 0 0 4 4 4 0 Ubiquitin family BCDHK_Adom3 PF10436.9 EGD88289.1 - 5.8e-45 153.0 0.1 1.2e-44 152.0 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGD88289.1 - 3.3e-06 27.6 0.0 1.7e-05 25.3 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGD88289.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EGD88289.1 - 0.18 11.7 0.0 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain SPC22 PF04573.12 EGD88291.1 - 6e-40 136.5 0.4 1.9e-37 128.4 0.4 2.1 1 1 0 1 1 1 1 Signal peptidase subunit Peptidase_C48 PF02902.19 EGD88292.2 - 4.6e-12 46.3 0.0 7e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.18 EGD88293.1 - 8.1e-55 185.0 0.1 1.4e-54 184.2 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Aminotran_1_2 PF00155.21 EGD88294.1 - 1.7e-26 93.2 0.0 2.1e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 EGD88294.1 - 0.00046 19.0 0.0 0.045 12.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III POT1 PF02765.17 EGD88295.1 - 5.8e-18 65.1 0.0 1.2e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FMO-like PF00743.19 EGD88296.2 - 1.2e-36 126.3 0.0 3.6e-22 78.5 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGD88296.2 - 1.5e-11 44.1 0.0 2.9e-09 36.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGD88296.2 - 1.8e-07 30.7 0.0 3.7e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGD88296.2 - 1.3e-05 24.6 0.0 6.8e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HDA2-3 PF11496.8 EGD88297.1 - 1.8e-35 122.6 1.5 2.6e-17 62.9 0.0 2.9 3 1 1 4 4 4 2 Class II histone deacetylase complex subunits 2 and 3 CENP-F_leu_zip PF10473.9 EGD88297.1 - 0.011 15.7 40.7 0.24 11.4 18.7 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.13 EGD88297.1 - 0.062 13.0 21.7 0.11 12.2 6.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Fib_alpha PF08702.10 EGD88297.1 - 1.9 8.7 20.5 5.8 7.1 7.7 3.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MIP PF00230.20 EGD88298.1 - 4.4e-45 154.2 11.9 5.5e-45 153.8 11.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Transglut_core PF01841.19 EGD88299.1 - 2.2e-11 44.2 0.2 6.4e-11 42.7 0.2 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.17 EGD88299.1 - 1.5e-08 34.2 0.1 3.7e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGD88299.1 - 1.2e-05 24.9 0.1 1.2e-05 24.9 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGD88299.1 - 0.0006 19.6 0.1 0.011 15.5 0.1 2.5 2 0 0 2 2 2 1 Variant SH3 domain Transglut_core2 PF13369.6 EGD88299.1 - 0.063 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily DHHA2 PF02833.14 EGD88300.1 - 5.4e-31 107.7 0.0 9.6e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EGD88300.1 - 1.1e-06 28.8 0.0 1.3e-05 25.4 0.0 2.5 1 1 0 1 1 1 1 DHH family PLU-1 PF08429.11 EGD88301.2 - 4.2e-110 368.1 15.9 1.1e-107 360.1 14.5 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 EGD88301.2 - 1.3e-42 144.8 1.0 4.4e-42 143.1 0.4 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 EGD88301.2 - 1.9e-12 47.4 5.2 6e-12 45.8 5.2 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.29 EGD88301.2 - 9.1e-10 38.3 18.6 1.2e-07 31.5 9.4 3.6 3 0 0 3 3 3 2 PHD-finger PHD_4 PF16866.5 EGD88301.2 - 0.24 11.5 11.0 0.16 12.1 4.6 2.9 2 0 0 2 2 2 0 PHD-finger Cwf_Cwc_15 PF04889.12 EGD88302.1 - 0.0029 17.4 1.1 0.0031 17.3 1.1 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 EGD88302.1 - 0.067 13.6 4.6 0.096 13.1 4.6 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FANCL_C PF11793.8 EGD88303.2 - 1.1e-05 25.5 3.9 1.8e-05 24.8 3.9 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 EGD88303.2 - 0.024 14.9 1.9 0.044 14.0 1.9 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.29 EGD88303.2 - 0.067 13.1 5.9 0.12 12.3 5.9 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 EGD88303.2 - 0.15 12.0 5.0 0.11 12.4 2.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Thymidylate_kin PF02223.17 EGD88304.1 - 3.4e-43 147.5 0.0 4.1e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 EGD88304.1 - 0.00059 20.1 0.0 0.00087 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGD88304.1 - 0.0012 18.3 0.1 0.0031 17.0 0.0 1.6 2 1 0 2 2 2 1 Chromatin associated protein KTI12 TGT PF01702.18 EGD88305.2 - 3e-61 207.5 0.0 3.6e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MFS_1 PF07690.16 EGD88306.1 - 3e-33 115.2 27.6 3e-33 115.2 27.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MTHFR PF02219.17 EGD88307.2 - 5.7e-90 301.5 0.0 9.5e-90 300.8 0.0 1.4 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase FLILHELTA PF10306.9 EGD88308.1 - 3.9e-28 97.7 0.0 6.8e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EGD88308.1 - 0.0014 19.1 0.2 0.0029 18.1 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF2208 PF09973.9 EGD88308.1 - 0.087 12.4 0.0 0.97 9.0 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) NDK PF00334.19 EGD88309.1 - 2e-55 186.5 0.0 2.3e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.26 EGD88310.2 - 3e-138 461.7 7.8 4e-138 461.3 7.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGD88310.2 - 1.2e-16 60.7 1.1 1.2e-15 57.6 0.3 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EGD88310.2 - 3e-08 33.8 0.1 9e-08 32.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) FAD_binding_3 PF01494.19 EGD88314.2 - 4.5e-28 98.5 0.0 2.7e-27 96.0 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Glyco_hydro_16 PF00722.21 EGD88315.1 - 3.1e-06 26.8 0.0 7.5e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Ribosomal_L1 PF00687.21 EGD88316.1 - 7.7e-34 117.2 0.0 1.2e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.11 EGD88317.1 - 3e-30 105.0 1.5 6.1e-30 104.0 1.5 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EGD88317.1 - 1.2e-05 25.2 2.2 2.8e-05 24.1 0.3 2.4 1 1 1 2 2 2 1 Vps51/Vps67 UPF0242 PF06785.11 EGD88317.1 - 0.0067 16.6 0.3 0.015 15.4 0.3 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 EGD88317.1 - 0.0083 15.0 3.0 0.013 14.4 3.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein KxDL PF10241.9 EGD88317.1 - 0.0085 16.3 0.6 0.03 14.6 0.2 2.2 2 1 0 2 2 2 1 Uncharacterized conserved protein Sec8_exocyst PF04048.14 EGD88317.1 - 0.01 15.8 0.6 0.02 14.8 0.6 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain IFT20 PF14931.6 EGD88317.1 - 0.012 15.7 2.3 0.04 14.1 2.3 1.8 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 COG5 PF10392.9 EGD88317.1 - 0.023 14.9 1.4 0.035 14.3 0.5 1.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Vps54_N PF10475.9 EGD88317.1 - 0.03 13.6 0.1 0.056 12.7 0.1 1.4 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Bul1_C PF04426.12 EGD88317.1 - 0.042 13.3 1.4 1.6 8.1 0.1 2.2 1 1 1 2 2 2 0 Bul1 C terminus Atg14 PF10186.9 EGD88317.1 - 0.052 12.6 2.2 0.069 12.2 2.2 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2120 PF09893.9 EGD88317.1 - 0.083 13.0 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) DUF4795 PF16043.5 EGD88317.1 - 0.14 11.8 2.3 0.26 10.9 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) IFT57 PF10498.9 EGD88317.1 - 0.31 10.0 5.1 0.033 13.2 0.7 1.5 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 PLC-beta_C PF08703.10 EGD88317.1 - 1.8 8.5 7.5 1.9 8.4 5.2 2.2 2 1 0 2 2 2 0 PLC-beta C terminal DUF1690 PF07956.11 EGD88317.1 - 2.8 8.4 5.9 1 9.8 2.9 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Herpes_TAF50 PF03326.13 EGD88318.1 - 0.058 12.1 2.8 2.4 6.7 1.6 2.3 2 0 0 2 2 2 0 Herpesvirus transcription activation factor (transactivator) ParA PF10609.9 EGD88320.2 - 8.9e-61 205.5 0.0 3.4e-60 203.5 0.0 1.7 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SEP PF08059.13 EGD88321.1 - 3.4e-23 82.0 0.1 7.5e-23 80.9 0.1 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EGD88321.1 - 5.7e-14 52.1 0.0 8.8e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EGD88321.1 - 7.6e-14 51.3 0.0 1.3e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 EGD88321.1 - 0.0015 18.2 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain TOM13 PF08219.11 EGD88322.1 - 9e-34 115.3 0.0 1.2e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 EGD88323.1 - 1.1e-20 74.2 0.1 1.8e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein DUF5326 PF17260.2 EGD88323.1 - 0.082 13.1 0.4 0.15 12.2 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5326) TAFII28 PF04719.14 EGD88324.1 - 8.7e-29 99.5 0.3 3.4e-26 91.2 0.1 2.3 2 0 0 2 2 2 2 hTAFII28-like protein conserved region SRP-alpha_N PF04086.13 EGD88324.1 - 1.4 8.8 12.0 0.17 11.8 2.2 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal SAM_decarbox PF01536.16 EGD88325.1 - 3.3e-130 434.2 0.0 4e-130 433.9 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TAF6_C PF07571.13 EGD88327.2 - 1.4e-30 105.4 0.0 3.1e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EGD88327.2 - 4.1e-25 87.7 0.0 2.1e-24 85.5 0.0 2.2 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 EGD88327.2 - 0.0015 18.6 0.1 0.0044 17.1 0.1 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EGD88327.2 - 0.0097 16.3 0.0 0.023 15.0 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EGD88327.2 - 0.0098 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 EGD88327.2 - 0.063 13.6 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF4 PF05236.14 EGD88327.2 - 0.12 12.1 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Rota_NS35 PF02509.14 EGD88327.2 - 0.18 10.8 0.1 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 CRAL_TRIO PF00650.20 EGD88328.2 - 3e-12 46.5 0.0 4.2e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain RNA_pol_Rpc4 PF05132.14 EGD88328.2 - 0.055 13.9 3.5 0.073 13.5 3.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Amelin PF05111.12 EGD88328.2 - 1.1 8.3 8.1 1.5 7.9 8.1 1.1 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) SspB PF04386.13 EGD88328.2 - 2 8.3 6.8 3.2 7.6 6.8 1.3 1 0 0 1 1 1 0 Stringent starvation protein B DUF3275 PF11679.8 EGD88328.2 - 3.7 7.5 8.6 5.4 6.9 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) IPP-2 PF04979.14 EGD88329.1 - 4.9e-20 72.6 17.6 4.9e-20 72.6 17.6 2.6 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) FAM217 PF15344.6 EGD88329.1 - 0.015 15.2 3.0 0.015 15.2 3.0 2.0 2 1 0 2 2 2 0 FAM217 family ELFV_dehydrog PF00208.21 EGD88332.1 - 3.8e-80 269.1 0.8 4.8e-80 268.8 0.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EGD88332.1 - 1.8e-50 170.1 0.0 3.7e-50 169.2 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DPBB_1 PF03330.18 EGD88334.1 - 0.003 17.8 0.0 0.0078 16.5 0.0 1.7 1 1 0 1 1 1 1 Lytic transglycolase MFS_1 PF07690.16 EGD88336.2 - 5.8e-13 48.5 35.4 1.2e-10 40.9 35.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD88336.2 - 0.00079 18.4 11.3 0.00079 18.4 11.3 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Chloroa_b-bind PF00504.21 EGD88336.2 - 0.14 12.7 0.5 0.59 10.6 0.1 2.2 2 0 0 2 2 2 0 Chlorophyll A-B binding protein Ribonuc_red_lgC PF02867.15 EGD88337.2 - 1.6e-186 620.9 0.0 2.1e-186 620.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGD88337.2 - 8.2e-26 89.8 0.0 1.8e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGD88337.2 - 6e-13 49.2 0.1 2.2e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain QWRF PF04484.12 EGD88338.2 - 3.4 7.3 6.6 3.9 7.1 6.6 1.2 1 0 0 1 1 1 0 QWRF family SPX PF03105.19 EGD88338.2 - 5 6.9 8.1 5.7 6.8 8.1 1.0 1 0 0 1 1 1 0 SPX domain PRK PF00485.18 EGD88339.1 - 0.00047 19.9 0.0 0.00066 19.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGD88339.1 - 0.0013 19.3 0.1 0.057 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EGD88339.1 - 0.0029 16.8 0.0 0.0044 16.2 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 EGD88339.1 - 0.0035 17.5 0.2 0.56 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EGD88339.1 - 0.0041 17.6 0.0 0.0064 16.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGD88339.1 - 0.0057 17.0 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 EGD88339.1 - 0.017 14.4 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain MeaB PF03308.16 EGD88339.1 - 0.048 12.6 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF463 PF04317.12 EGD88339.1 - 0.05 12.5 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_17 PF13207.6 EGD88339.1 - 0.062 13.7 0.1 3.9 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGD88339.1 - 0.092 12.0 0.3 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 EGD88339.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EGD88339.1 - 0.15 11.7 0.0 5.9 6.5 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase cobW PF02492.19 EGD88339.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 EGD88339.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_11 PF13086.6 EGD88339.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mur_ligase_M PF08245.12 EGD88341.1 - 1.2e-06 28.7 0.0 2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EGD88341.1 - 0.058 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Peptidase_M24 PF00557.24 EGD88343.1 - 2.3e-43 148.3 0.0 2.8e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.19 EGD88343.1 - 0.088 11.5 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Pectinesterase DnaJ PF00226.31 EGD88344.1 - 1.6e-23 82.6 0.3 2.8e-23 81.8 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.22 EGD88345.2 - 1e-60 205.5 4.2 1.5e-60 204.9 4.2 1.2 1 0 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.21 EGD88346.1 - 6.9e-89 299.0 0.1 1.5e-52 179.4 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EGD88346.1 - 4.4e-36 123.5 0.0 7.4e-36 122.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGD88346.1 - 4.7e-26 91.6 0.0 8e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGD88346.1 - 1.1e-06 28.3 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EGD88346.1 - 0.00098 18.3 0.1 0.005 16.0 0.1 1.9 1 1 0 1 1 1 1 NAD synthase UQ_con PF00179.26 EGD88347.1 - 8.9e-47 158.3 0.0 1e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGD88347.1 - 1.3e-05 24.9 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGD88347.1 - 0.21 11.9 0.9 0.43 10.9 0.8 1.6 1 1 0 1 1 1 0 RWD domain G-patch PF01585.23 EGD88348.1 - 7.6e-12 44.9 1.4 1.5e-11 44.0 1.4 1.4 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EGD88348.1 - 0.00015 21.5 0.0 0.00034 20.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mac PF12464.8 EGD88348.1 - 0.047 13.9 1.6 0.1 12.9 0.6 2.0 2 0 0 2 2 2 0 Maltose acetyltransferase AMP-binding PF00501.28 EGD88349.2 - 6.2e-55 186.5 0.0 7.1e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD88349.2 - 1.1e-07 32.7 0.2 2.3e-07 31.7 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RTX_C PF08339.10 EGD88349.2 - 0.0089 16.1 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 RTX C-terminal domain YCII PF03795.14 EGD88350.1 - 0.00017 22.0 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Fungal_trans PF04082.18 EGD88351.2 - 1.9e-14 53.4 0.9 1.1e-13 50.8 0.3 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 EGD88352.2 - 9.6e-15 54.3 0.0 8.4e-14 51.2 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Rad10 PF03834.14 EGD88353.1 - 1.4e-48 163.6 0.0 2e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EGD88353.1 - 0.00042 20.9 0.0 0.00093 19.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Tape_meas_lam_C PF09718.10 EGD88353.1 - 0.082 13.0 0.8 12 6.1 0.0 2.6 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) HHH_2 PF12826.7 EGD88353.1 - 0.09 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.23 EGD88353.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif RRM_1 PF00076.22 EGD88354.2 - 2.7e-59 196.9 0.0 1.6e-18 66.2 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EGD88354.2 - 1.6e-07 31.7 2.1 2.3 8.4 0.0 5.4 4 3 3 7 7 7 3 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 EGD88354.2 - 6.2e-05 22.9 0.5 0.73 9.6 0.0 3.4 2 2 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EGD88354.2 - 0.00034 20.7 0.1 5.2 7.3 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif RRM_5 PF13893.6 EGD88354.2 - 0.0037 16.9 0.0 1.7 8.2 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.28 EGD88355.1 - 2.4e-08 34.0 0.0 2.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.21 EGD88356.1 - 9.9e-106 354.2 35.8 1.2e-105 353.9 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD88356.1 - 3.3e-16 59.1 39.9 4.4e-16 58.7 39.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.11 EGD88356.1 - 0.014 15.7 2.2 0.014 15.7 2.2 3.7 3 1 0 4 4 4 0 Domain of unknown function (DUF1772) Cupin_8 PF13621.6 EGD88357.1 - 1.3e-23 84.1 0.0 1.8e-23 83.6 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGD88357.1 - 0.00014 21.4 0.0 0.00037 20.1 0.0 1.6 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 EGD88357.1 - 0.00031 21.1 0.0 0.0009 19.7 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EGD88357.1 - 0.0019 17.9 0.0 0.0065 16.2 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Fungal_trans PF04082.18 EGD88358.2 - 5.1e-17 61.8 0.0 9.7e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD88358.2 - 4.7e-06 26.6 14.9 8.6e-06 25.8 14.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.10 EGD88358.2 - 0.0083 16.4 0.2 0.018 15.4 0.2 1.5 1 0 0 1 1 1 1 HalX domain CK_II_beta PF01214.18 EGD88359.1 - 5.3e-75 251.2 0.0 1e-74 250.3 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.8 EGD88359.1 - 0.032 15.2 5.6 0.032 15.2 5.6 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.11 EGD88359.1 - 0.074 11.6 1.3 0.11 11.0 1.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PTPRCAP PF15713.5 EGD88359.1 - 3.3 8.0 7.8 21 5.4 5.2 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated bZIP_2 PF07716.15 EGD88360.1 - 0.029 14.4 6.1 0.045 13.8 6.1 1.2 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 EGD88360.1 - 0.03 14.4 7.3 0.05 13.7 7.3 1.2 1 0 0 1 1 1 0 bZIP transcription factor Aminotran_4 PF01063.19 EGD88362.2 - 2.5e-36 125.6 0.0 3.3e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 EGD88363.2 - 4.2e-19 69.0 0.0 2e-18 66.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD88363.2 - 1.2e-09 37.8 0.0 1e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_M49 PF03571.15 EGD88364.1 - 1.3e-244 812.7 0.0 2.9e-244 811.6 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M49 DUF3060 PF11259.8 EGD88365.2 - 0.014 15.1 0.3 0.56 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) Ribosomal_60s PF00428.19 EGD88365.2 - 0.12 13.0 0.6 0.23 12.1 0.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein BHD_1 PF10403.9 EGD88369.2 - 0.013 15.3 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 WD40 PF00400.32 EGD88370.2 - 1.5e-21 76.3 27.6 6.5e-06 26.8 0.2 7.2 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD88370.2 - 2.8e-11 43.6 8.8 0.00017 21.8 0.2 4.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EGD88370.2 - 0.0014 18.6 10.6 0.3 11.0 0.3 2.8 2 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Ank_4 PF13637.6 EGD88371.2 - 9.2e-19 67.6 3.9 3.5e-09 37.0 0.0 4.4 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGD88371.2 - 1e-18 67.7 0.5 7.9e-10 39.2 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) GDPD PF03009.17 EGD88371.2 - 1.2e-15 58.0 0.0 2.8e-15 56.8 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_5 PF13857.6 EGD88371.2 - 1.4e-09 38.0 0.6 0.084 13.2 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD88371.2 - 1.7e-09 37.1 4.3 0.073 13.7 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 EGD88371.2 - 4.8e-06 26.8 3.2 4.7 7.8 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Sugar_tr PF00083.24 EGD88374.1 - 5.2e-97 325.5 24.9 4.1e-96 322.6 24.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGD88374.1 - 6.6e-28 97.7 23.6 6.6e-28 97.7 23.6 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 EGD88375.2 - 9.9e-40 136.5 40.2 1.2e-39 136.2 40.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC_tran PF00005.27 EGD88377.1 - 3e-46 157.3 0.7 1.8e-22 80.3 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EGD88377.1 - 2e-21 75.8 7.9 2e-21 75.8 7.9 3.6 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.6 EGD88377.1 - 2.1e-17 63.9 0.8 0.0024 17.7 0.0 4.9 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGD88377.1 - 1.2e-11 44.5 0.3 0.0051 16.3 0.0 4.5 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGD88377.1 - 3e-06 27.6 0.0 0.0077 16.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGD88377.1 - 5.9e-06 26.3 0.0 0.11 12.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGD88377.1 - 1.4e-05 25.0 1.8 0.091 12.7 0.1 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EGD88377.1 - 1.6e-05 25.4 0.4 0.18 12.2 0.2 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EGD88377.1 - 2.1e-05 25.2 18.4 0.014 15.9 0.0 4.8 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.6 EGD88377.1 - 2.2e-05 24.1 0.2 0.27 11.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 EGD88377.1 - 7.6e-05 22.5 0.0 0.01 15.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGD88377.1 - 8.4e-05 22.8 1.4 0.55 10.4 0.1 3.2 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EGD88377.1 - 9.5e-05 23.0 4.8 0.35 11.4 0.0 3.8 5 0 0 5 5 4 2 AAA domain AAA_24 PF13479.6 EGD88377.1 - 0.00026 20.8 0.8 0.82 9.3 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 EGD88377.1 - 0.00031 21.0 2.6 0.22 11.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 EGD88377.1 - 0.00038 20.3 14.6 0.2 11.3 0.0 5.0 4 1 0 4 4 4 1 AAA ATPase domain AAA PF00004.29 EGD88377.1 - 0.002 18.6 0.1 0.93 9.9 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 EGD88377.1 - 0.0033 17.1 0.1 3.2 7.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EGD88377.1 - 0.0037 17.2 0.1 1.3 8.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 EGD88377.1 - 0.0076 16.6 0.1 5.6 7.4 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Dynamin_N PF00350.23 EGD88377.1 - 0.012 15.7 6.9 1.8 8.6 0.0 3.9 4 1 1 5 5 4 0 Dynamin family Zeta_toxin PF06414.12 EGD88377.1 - 0.015 14.6 1.6 3.4 6.9 0.1 3.1 3 0 0 3 3 3 0 Zeta toxin MeaB PF03308.16 EGD88377.1 - 0.016 14.2 3.5 1.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Peripla_BP_3 PF13377.6 EGD88377.1 - 0.017 15.5 0.1 26 5.1 0.0 3.4 3 0 0 3 3 3 0 Periplasmic binding protein-like domain Rad17 PF03215.15 EGD88377.1 - 0.017 15.0 0.2 1.4 8.9 0.0 3.1 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_14 PF13173.6 EGD88377.1 - 0.018 15.1 0.5 13 5.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 EGD88377.1 - 0.04 14.1 0.1 8.8 6.6 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 EGD88377.1 - 0.044 13.4 0.0 2.9 7.5 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 EGD88377.1 - 0.046 13.6 0.1 3 7.7 0.0 2.9 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 EGD88377.1 - 0.054 13.5 0.3 17 5.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF2813 PF11398.8 EGD88377.1 - 0.086 12.1 2.0 0.21 10.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) cobW PF02492.19 EGD88377.1 - 0.097 12.3 2.3 1.9 8.0 0.4 2.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EGD88377.1 - 0.1 12.1 0.0 6.1 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF1279 PF06916.13 EGD88380.2 - 1.2e-25 89.8 0.0 1.7e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L3 PF00297.22 EGD88381.1 - 2.8e-16 59.5 4.0 2e-14 53.3 0.5 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Coa1 PF08695.10 EGD88382.1 - 1.7e-43 147.1 0.0 2.1e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF3784 PF12650.7 EGD88383.1 - 0.0068 16.6 0.1 0.039 14.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3784) ABC2_membrane_3 PF12698.7 EGD88383.1 - 5.4 6.0 7.8 48 2.9 8.2 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein JmjC PF02373.22 EGD88384.2 - 1.9e-08 34.8 0.8 5.7e-07 30.0 0.8 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 EGD88384.2 - 2.4e-06 27.7 8.3 2.4e-06 27.7 8.3 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 EGD88384.2 - 0.0089 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain zinc_ribbon_15 PF17032.5 EGD88384.2 - 1.2 10.0 14.9 1.3 9.8 2.1 3.4 3 0 0 3 3 3 0 zinc-ribbon family UbiA PF01040.18 EGD88385.1 - 1e-42 146.2 18.4 1.3e-42 145.9 18.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Flavoprotein PF02441.19 EGD88386.1 - 1.9e-44 151.2 0.0 2.7e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.24 EGD88387.1 - 5.4e-15 55.3 0.0 9.3e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin CCDC23 PF15674.5 EGD88388.1 - 0.46 10.5 17.4 0.06 13.3 7.8 2.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 23 DUF1216 PF06746.11 EGD88388.1 - 2.3 8.2 12.5 4.3 7.4 5.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1216) CTP_transf_like PF01467.26 EGD88389.1 - 9.3e-26 90.7 0.0 3.5e-22 79.1 0.0 3.8 2 1 0 3 3 3 2 Cytidylyltransferase-like FAD-SLDH PF12318.8 EGD88390.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase PRELI PF04707.14 EGD88391.1 - 3.8e-45 153.5 0.4 4.5e-45 153.3 0.4 1.1 1 0 0 1 1 1 1 PRELI-like family Mito_carr PF00153.27 EGD88393.1 - 8.6e-73 240.4 1.1 3.2e-23 81.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGD88393.1 - 0.00026 20.2 0.6 0.017 14.3 0.0 2.9 2 1 2 4 4 4 2 Gammaproteobacterial serine protease RRM_1 PF00076.22 EGD88394.1 - 2.5e-12 46.4 0.0 3.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGD88394.1 - 0.00039 20.4 0.0 0.00054 19.9 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sedlin_N PF04628.13 EGD88395.1 - 2.4e-15 56.8 0.0 3.8e-15 56.2 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Ribosomal_L18 PF17135.4 EGD88396.1 - 5.9e-94 312.7 1.6 6.6e-94 312.6 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EGD88396.1 - 2.2e-05 25.1 0.1 0.00014 22.5 0.1 2.2 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A AAA_19 PF13245.6 EGD88396.1 - 0.051 13.9 0.0 0.069 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Aldedh PF00171.22 EGD88397.1 - 2.6e-10 39.4 4.0 7.5e-10 37.9 2.5 2.2 2 1 0 2 2 2 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGD88397.1 - 0.029 13.8 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) HrpB1_HrpK PF09613.10 EGD88398.2 - 0.035 13.7 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) NifU_N PF01592.16 EGD88399.2 - 6.2e-44 149.2 0.1 7.7e-44 148.9 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 EGD88399.2 - 0.015 15.6 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain Oxidored_q6 PF01058.22 EGD88400.2 - 7.1e-18 64.7 0.0 1.3e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit UDG PF03167.19 EGD88401.1 - 1.5e-22 80.2 0.1 2.9e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily UCH PF00443.29 EGD88403.1 - 8.6e-36 123.7 0.0 1.2e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EGD88403.1 - 1.9e-25 88.4 1.4 2.4e-23 81.6 0.2 2.7 2 0 0 2 2 2 2 Variant UBP zinc finger zf-UBP PF02148.19 EGD88403.1 - 4.8e-23 81.3 17.4 1.2e-19 70.3 1.4 3.1 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGD88403.1 - 3.2e-15 56.6 0.0 7.1e-13 48.8 0.0 3.3 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 EGD88403.1 - 1.8e-14 53.3 0.1 4.3e-07 29.7 0.0 2.7 3 0 0 3 3 3 2 UBA/TS-N domain UBA_4 PF14555.6 EGD88403.1 - 0.0098 15.7 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain zf-C3HC4_2 PF13923.6 EGD88403.1 - 4.3 7.2 8.0 0.33 10.8 1.8 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FtsJ PF01728.19 EGD88404.1 - 2.7e-55 187.2 0.0 3.2e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EGD88404.1 - 1.7e-05 24.6 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EGD88404.1 - 0.00082 19.2 0.0 0.0023 17.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain ThiF PF00899.21 EGD88405.2 - 1.1e-31 110.1 0.0 1.4e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family ATPase-cat_bd PF12156.8 EGD88405.2 - 0.042 14.6 1.8 21 5.9 0.0 3.2 3 0 0 3 3 3 0 Putative metal-binding domain of cation transport ATPase His_biosynth PF00977.21 EGD88407.1 - 5.5e-45 153.6 0.5 1.9e-44 151.9 0.5 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EGD88407.1 - 7.7e-24 84.5 0.0 1.3e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EGD88407.1 - 5.9e-10 39.3 0.0 3.1e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGD88407.1 - 9.6e-09 35.1 0.0 2.1e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EGD88407.1 - 0.075 12.8 0.1 0.94 9.3 0.0 2.3 2 0 0 2 2 2 0 DJ-1/PfpI family BPL_N PF09825.9 EGD88407.1 - 0.12 11.4 0.0 0.48 9.4 0.0 1.8 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal DNA_pol_E_B PF04042.16 EGD88408.1 - 5.7e-32 110.8 0.1 9.8e-32 110.0 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SHNi-TPR PF10516.9 EGD88409.1 - 3.5e-17 61.6 2.2 1.2e-14 53.4 0.2 2.6 2 0 0 2 2 2 2 SHNi-TPR TPR_12 PF13424.6 EGD88409.1 - 2.5e-08 34.1 3.4 0.00052 20.2 1.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 EGD88409.1 - 0.015 15.4 1.8 0.015 15.4 1.8 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 EGD88409.1 - 2.7 8.1 7.7 0.59 10.2 0.7 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat XhlA PF10779.9 EGD88409.1 - 4.9 7.4 4.9 9.2 6.6 0.6 2.8 2 0 0 2 2 2 0 Haemolysin XhlA Yippee-Mis18 PF03226.14 EGD88410.1 - 1e-20 73.9 0.0 1.4e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Transp_Tc5_C PF04236.15 EGD88410.1 - 0.022 15.1 0.2 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain RIG-I_C-RD PF11648.8 EGD88410.1 - 0.036 14.3 2.3 0.38 11.0 2.3 2.0 1 1 0 1 1 1 0 C-terminal domain of RIG-I zf-Sec23_Sec24 PF04810.15 EGD88410.1 - 0.14 12.3 2.1 1.6 8.9 0.3 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Thioredoxin PF00085.20 EGD88411.1 - 3.4e-68 226.1 7.9 1.3e-31 108.6 0.1 4.3 4 0 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.6 EGD88411.1 - 6.1e-52 176.2 5.4 3.1e-38 131.5 1.4 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 EGD88411.1 - 3.2e-09 36.6 1.8 0.00058 19.3 0.0 3.7 2 1 1 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGD88411.1 - 8.6e-09 35.8 2.7 0.00076 19.9 0.0 4.0 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGD88411.1 - 1.2e-08 35.1 0.2 0.08 13.3 0.0 4.9 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EGD88411.1 - 4.9e-08 33.0 0.0 0.012 15.8 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 EGD88411.1 - 1.4e-07 31.5 0.2 0.0011 18.8 0.1 2.9 3 0 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.17 EGD88411.1 - 5.1e-06 25.8 7.6 8.6e-05 21.7 7.5 2.3 1 1 0 1 1 1 1 Calsequestrin Redoxin PF08534.10 EGD88411.1 - 7.7e-05 22.4 0.2 0.66 9.7 0.1 2.8 2 0 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.6 EGD88411.1 - 0.02 14.9 0.4 0.093 12.8 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.6 EGD88411.1 - 1.5 8.9 5.3 16 5.7 0.0 3.4 4 0 0 4 4 4 0 Thioredoxin zf-RING_2 PF13639.6 EGD88413.2 - 0.012 15.9 5.3 0.021 15.1 5.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 EGD88413.2 - 0.028 14.3 8.9 0.051 13.4 8.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PDZ_assoc PF10600.9 EGD88413.2 - 0.06 14.2 1.2 0.06 14.2 1.2 2.7 2 1 1 3 3 3 0 PDZ-associated domain of NMDA receptors DUF1272 PF06906.11 EGD88413.2 - 0.099 12.7 4.7 0.18 11.9 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 EGD88413.2 - 0.18 11.6 5.8 0.37 10.6 5.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EGD88413.2 - 0.33 11.2 6.1 0.78 10.0 6.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Macoilin PF09726.9 EGD88413.2 - 0.52 8.8 8.8 0.97 7.9 8.8 1.4 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 EGD88413.2 - 0.57 8.8 7.7 0.75 8.4 7.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dicty_REP PF05086.12 EGD88413.2 - 0.76 7.7 7.9 1 7.2 7.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C3HC4 PF00097.25 EGD88413.2 - 0.96 9.4 7.6 1.8 8.5 7.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FRG2 PF15315.6 EGD88413.2 - 1.1 9.4 17.8 3.8 7.7 17.8 1.8 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 FYVE_2 PF02318.16 EGD88413.2 - 1.2 9.3 6.0 0.3 11.3 2.5 1.7 1 1 1 2 2 2 0 FYVE-type zinc finger CDC45 PF02724.14 EGD88413.2 - 2.2 6.5 11.7 3.4 5.9 11.7 1.2 1 0 0 1 1 1 0 CDC45-like protein HABP4_PAI-RBP1 PF04774.15 EGD88415.1 - 0.0067 17.3 3.1 0.0097 16.7 3.1 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family OST3_OST6 PF04756.13 EGD88416.1 - 1.7e-101 339.5 0.0 2.1e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 EGD88416.1 - 0.01 16.6 0.6 0.01 16.6 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Thioredoxin PF00085.20 EGD88416.1 - 0.02 14.8 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin MerC PF03203.14 EGD88416.1 - 0.21 12.1 4.6 2.3 8.7 0.4 3.0 3 0 0 3 3 3 0 MerC mercury resistance protein HALZ PF02183.18 EGD88417.2 - 0.0017 18.5 1.4 0.48 10.7 0.0 2.5 2 0 0 2 2 2 2 Homeobox associated leucine zipper PI3K_P85_iSH2 PF16454.5 EGD88417.2 - 0.017 14.7 0.3 0.017 14.7 0.3 1.8 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain GAS PF13851.6 EGD88417.2 - 0.021 14.2 1.3 0.042 13.2 1.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phlebovirus_NSM PF07246.11 EGD88417.2 - 0.024 14.0 0.3 0.024 14.0 0.3 1.7 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M CENP-F_leu_zip PF10473.9 EGD88417.2 - 0.028 14.4 3.3 0.1 12.6 2.6 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 EGD88417.2 - 0.037 14.5 0.9 0.13 12.8 0.9 1.9 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 EGD88417.2 - 0.041 14.0 0.3 0.041 14.0 0.3 2.9 3 0 0 3 3 3 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 EGD88417.2 - 0.061 13.4 3.0 0.17 12.0 3.0 1.8 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 EGD88417.2 - 0.083 12.7 0.3 0.27 11.0 0.1 1.9 1 1 1 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.8 EGD88417.2 - 0.19 11.9 3.4 0.54 10.5 3.4 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 EGD88417.2 - 0.39 11.7 0.3 0.39 11.7 0.3 4.1 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain TMCO5 PF14992.6 EGD88417.2 - 1.4 8.5 5.9 0.19 11.3 0.9 2.0 2 0 0 2 2 2 0 TMCO5 family Complex1_LYR PF05347.15 EGD88418.1 - 0.0005 20.1 0.2 0.00088 19.3 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) zinc_ribbon_6 PF14599.6 EGD88419.1 - 3.2e-25 87.9 0.8 3.2e-25 87.9 0.8 3.9 4 0 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 EGD88419.1 - 9.1e-20 70.9 19.3 9.1e-20 70.9 19.3 3.8 2 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EGD88419.1 - 6.9e-08 32.7 8.8 6.9e-08 32.7 8.8 5.6 2 2 5 7 7 7 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGD88419.1 - 6.1e-06 26.0 6.6 6.1e-06 26.0 6.6 4.8 4 1 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGD88419.1 - 1.5e-05 24.8 8.4 1.5e-05 24.8 8.4 6.3 5 1 1 6 6 6 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGD88419.1 - 0.00012 21.8 8.9 0.00012 21.8 8.9 6.1 3 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGD88419.1 - 0.0033 17.3 9.9 0.0033 17.3 9.9 5.5 4 2 1 5 5 5 1 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 EGD88419.1 - 0.0046 16.9 1.9 0.0046 16.9 1.9 5.5 5 3 3 8 8 8 1 Prokaryotic RING finger family 1 Rrn6 PF10214.9 EGD88420.2 - 8.1e-121 405.1 0.2 1.1e-120 404.7 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 EGD88421.1 - 3.5e-24 84.8 0.1 1.4e-23 82.8 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 ERM PF00769.19 EGD88421.1 - 0.75 9.6 20.5 1.1 9.0 20.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF334 PF03904.13 EGD88421.1 - 0.75 9.3 9.0 1 8.8 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Exonuc_VII_L PF02601.15 EGD88421.1 - 1.6 8.2 10.1 2.4 7.7 10.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EGD88421.1 - 2.5 5.9 7.3 2.9 5.7 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 EGD88421.1 - 3.5 6.6 16.2 5.1 6.1 16.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Calpain_III PF01067.22 EGD88421.1 - 4.1 7.7 5.9 6.3 7.1 5.9 1.2 1 0 0 1 1 1 0 Calpain large subunit, domain III Ku_C PF03730.14 EGD88421.1 - 4.1 8.2 7.5 1.5 9.5 3.8 2.0 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm LMBR1 PF04791.16 EGD88421.1 - 4.2 6.2 4.8 4.7 6.0 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.12 EGD88421.1 - 6.8 5.1 7.2 8.9 4.7 7.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 EGD88421.1 - 7.4 5.8 11.7 11 5.3 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Septin PF00735.18 EGD88423.2 - 7.9e-98 327.2 2.0 9.7e-98 326.9 2.0 1.1 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 EGD88423.2 - 0.14 11.7 0.2 8.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Guanylate_kin PF00625.21 EGD88424.2 - 1.2e-61 207.6 0.0 1.5e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 EGD88424.2 - 6.3e-07 29.9 0.1 8.8e-07 29.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EGD88424.2 - 1.2e-05 25.4 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EGD88424.2 - 0.00018 21.7 0.4 0.0041 17.3 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGD88424.2 - 0.00018 22.0 0.3 0.00086 19.9 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGD88424.2 - 0.00022 21.5 0.0 0.00049 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGD88424.2 - 0.0011 19.5 0.0 0.0021 18.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 EGD88424.2 - 0.0011 19.2 0.0 0.0026 18.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 EGD88424.2 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EGD88424.2 - 0.0026 17.5 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGD88424.2 - 0.0037 16.8 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_29 PF13555.6 EGD88424.2 - 0.0068 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 EGD88424.2 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EGD88424.2 - 0.012 15.9 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EGD88424.2 - 0.013 15.5 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EGD88424.2 - 0.016 14.5 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ATPase_2 PF01637.18 EGD88424.2 - 0.02 14.8 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 EGD88424.2 - 0.031 13.3 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EGD88424.2 - 0.032 14.0 0.1 0.12 12.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EGD88424.2 - 0.033 14.6 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGD88424.2 - 0.034 14.1 0.1 0.17 11.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGD88424.2 - 0.035 13.8 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 EGD88424.2 - 0.044 13.7 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 EGD88424.2 - 0.065 13.1 0.1 0.11 12.4 0.1 1.5 1 1 0 1 1 1 0 NTPase Adeno_IVa2 PF02456.15 EGD88424.2 - 0.086 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Mg_chelatase PF01078.21 EGD88424.2 - 0.091 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 EGD88424.2 - 0.093 12.3 0.0 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 EGD88424.2 - 0.11 11.8 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 EGD88424.2 - 0.13 12.8 0.1 0.27 11.7 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 EGD88424.2 - 0.17 12.3 0.5 1.9 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EGD88424.2 - 0.24 11.2 0.1 1.7 8.5 0.0 2.0 2 0 0 2 2 2 0 Deoxynucleoside kinase GRAB PF10375.9 EGD88425.1 - 1.3e-07 31.2 0.2 1.3e-07 31.2 0.2 1.9 2 0 0 2 2 2 1 GRIP-related Arf-binding domain Fez1 PF06818.15 EGD88425.1 - 9e-05 23.0 48.9 0.011 16.2 6.1 3.3 2 1 1 3 3 3 2 Fez1 Golgin_A5 PF09787.9 EGD88425.1 - 0.0018 17.8 57.5 0.2 11.1 21.2 3.3 1 1 2 3 3 3 3 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 EGD88425.1 - 0.0072 16.4 14.4 0.69 10.0 8.0 3.2 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus HMMR_N PF15905.5 EGD88425.1 - 0.15 11.5 52.8 0.27 10.7 30.2 3.0 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal NPV_P10 PF05531.12 EGD88425.1 - 0.17 12.4 13.0 3.1 8.3 0.4 4.5 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein FliJ PF02050.16 EGD88425.1 - 0.22 11.7 44.3 0.043 14.0 15.3 3.7 1 1 2 3 3 3 0 Flagellar FliJ protein DUF812 PF05667.11 EGD88425.1 - 0.24 10.2 54.7 0.0049 15.8 35.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF812) HALZ PF02183.18 EGD88425.1 - 0.32 11.3 16.8 4.6 7.5 0.0 6.0 4 1 1 5 5 5 0 Homeobox associated leucine zipper Spc7 PF08317.11 EGD88425.1 - 0.47 9.3 54.6 1.3 7.8 31.0 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein CCCAP PF15964.5 EGD88425.1 - 0.72 8.1 51.2 6.7 4.9 27.0 2.2 1 1 1 2 2 2 0 Centrosomal colon cancer autoantigen protein family DUF641 PF04859.12 EGD88425.1 - 0.72 10.2 41.2 0.11 12.8 6.3 4.7 2 1 3 5 5 5 0 Plant protein of unknown function (DUF641) Filament PF00038.21 EGD88425.1 - 1.5 8.3 50.6 0.15 11.6 16.0 3.6 1 1 2 3 3 3 0 Intermediate filament protein FAM184 PF15665.5 EGD88425.1 - 2 8.2 50.1 0.25 11.1 11.9 3.4 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B DUF3584 PF12128.8 EGD88425.1 - 2 5.8 48.5 2.1 5.7 33.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) GAS PF13851.6 EGD88425.1 - 2.1 7.6 53.6 2.3 7.5 8.7 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 EGD88425.1 - 2.2 7.3 41.8 0.16 11.0 24.0 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 EGD88425.1 - 2.2 8.3 64.9 0.42 10.7 9.8 4.8 4 1 0 4 4 3 0 TPR/MLP1/MLP2-like protein COG5 PF10392.9 EGD88425.1 - 2.9 8.1 17.8 0.7 10.1 8.4 3.3 2 2 1 3 3 3 0 Golgi transport complex subunit 5 Bacillus_HBL PF05791.11 EGD88425.1 - 4.1 7.2 16.5 2.3 8.0 1.1 4.0 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) p450 PF00067.22 EGD88430.2 - 9.4e-62 209.2 0.0 1.2e-33 116.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DASH_Dad2 PF08654.10 EGD88431.2 - 1.4e-27 96.0 1.0 1.7e-27 95.7 1.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Rogdi_lz PF10259.9 EGD88431.2 - 0.0026 17.3 1.2 0.0028 17.2 1.2 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein APG6_N PF17675.1 EGD88431.2 - 0.0027 18.2 0.1 0.0039 17.7 0.1 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region NPV_P10 PF05531.12 EGD88431.2 - 0.0031 18.0 0.5 0.0049 17.3 0.5 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein MauJ PF17419.2 EGD88431.2 - 0.019 14.4 1.0 0.027 13.9 1.0 1.1 1 0 0 1 1 1 0 Methylamine utilization protein MauJ Baculo_PEP_C PF04513.12 EGD88431.2 - 0.02 15.0 0.4 0.022 14.8 0.4 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.11 EGD88431.2 - 0.02 14.7 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 HAUS6_N PF14661.6 EGD88431.2 - 0.024 14.2 0.2 0.028 14.0 0.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Seryl_tRNA_N PF02403.22 EGD88431.2 - 0.047 13.9 1.3 0.047 13.9 1.3 1.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LIF_OSM PF01291.17 EGD88431.2 - 0.077 13.1 0.2 0.097 12.8 0.2 1.1 1 0 0 1 1 1 0 LIF / OSM family DUF2730 PF10805.8 EGD88431.2 - 0.08 13.0 0.2 0.16 12.1 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) SKA1 PF07160.12 EGD88431.2 - 0.11 12.3 1.0 0.13 12.1 1.0 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Shugoshin_N PF07558.11 EGD88432.1 - 2.2e-18 65.9 2.6 2.2e-18 65.9 2.6 2.0 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 EGD88432.1 - 1.7e-10 40.5 8.9 1.7e-10 40.5 8.9 2.4 2 0 0 2 2 2 1 Shugoshin C terminus TetR_C_14 PF17754.1 EGD88432.1 - 0.051 13.5 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 MftR C-terminal domain Cep57_CLD_2 PF14197.6 EGD88432.1 - 0.46 10.6 5.5 0.11 12.7 0.9 2.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 PPI_Ypi1 PF07491.11 EGD88433.1 - 6.3e-26 90.0 1.0 1.4e-25 88.9 1.0 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor YL1 PF05764.13 EGD88433.1 - 2.9 7.9 10.4 2.9 7.9 9.3 1.6 1 1 1 2 2 2 0 YL1 nuclear protein ALAD PF00490.21 EGD88434.1 - 1.4e-120 402.2 0.0 1.7e-120 402.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Mac_assoc PF16628.5 EGD88435.2 - 1.7e-49 168.6 7.5 2.8e-49 167.8 7.5 1.3 1 0 0 1 1 1 1 Unstructured region on maltose acetyltransferase Hexapep PF00132.24 EGD88435.2 - 7.3e-13 47.7 6.1 4.6e-08 32.5 0.3 3.5 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 EGD88435.2 - 3.2e-10 40.1 0.0 6.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 EGD88435.2 - 2.7e-07 30.2 6.6 3.6e-06 26.6 0.4 3.1 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase FAD_binding_3 PF01494.19 EGD88436.2 - 2.9e-13 49.8 0.0 8.9e-13 48.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 EGD88436.2 - 0.018 14.1 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase CRM1_C PF08767.11 EGD88437.2 - 3.1e-135 450.5 4.9 3.1e-135 450.5 4.9 2.9 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EGD88437.2 - 1.1e-41 142.4 9.3 3.5e-41 140.7 6.8 3.3 2 1 1 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EGD88437.2 - 9.2e-34 114.9 4.1 4.9e-33 112.6 4.1 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EGD88437.2 - 2.9e-29 100.9 0.7 2.9e-29 100.9 0.7 2.9 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EGD88437.2 - 6.3e-20 70.4 1.3 1.4e-19 69.2 1.3 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EGD88437.2 - 5.7e-13 48.6 0.2 2.3e-12 46.6 0.2 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EGD88437.2 - 0.0027 17.6 0.3 0.3 11.0 0.0 4.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) HD_assoc PF13286.6 EGD88437.2 - 0.019 15.5 3.2 9.5 6.8 0.0 4.1 4 0 0 4 4 4 0 Phosphohydrolase-associated domain CIAPIN1 PF05093.13 EGD88438.1 - 2.9e-42 143.3 3.6 6.5e-42 142.1 3.6 1.6 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EGD88438.1 - 6e-34 117.1 0.0 1.3e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Rft-1 PF04506.13 EGD88439.2 - 4.1e-130 434.9 13.7 4.8e-130 434.7 13.7 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 EGD88439.2 - 0.0088 15.3 19.3 0.033 13.4 6.7 3.3 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 EGD88439.2 - 0.16 11.3 26.0 0.04 13.3 15.2 3.0 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein Rep_fac-A_C PF08646.10 EGD88440.1 - 9.3e-48 161.7 8.7 1.5e-46 157.8 5.4 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EGD88440.1 - 2.6e-35 120.3 0.2 5.8e-35 119.1 0.1 1.7 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 EGD88440.1 - 1.3e-19 70.1 0.1 2.8e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EGD88440.1 - 1.3e-12 47.5 0.1 1.5e-07 31.3 0.0 4.0 3 1 1 4 4 4 3 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EGD88440.1 - 0.0095 15.7 1.0 0.16 11.7 0.4 2.6 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 Ribosomal_L37ae PF01780.19 EGD88440.1 - 0.026 14.6 0.5 0.068 13.3 0.5 1.6 1 0 0 1 1 1 0 Ribosomal L37ae protein family DUF4503 PF14951.6 EGD88440.1 - 0.037 12.5 0.3 0.058 11.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) MHYT PF03707.16 EGD88444.2 - 3.4e-17 62.3 18.2 1e-09 38.4 1.1 3.7 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat HMA PF00403.26 EGD88445.1 - 1.9e-14 53.9 0.6 2.2e-14 53.6 0.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Vps4_C PF09336.10 EGD88445.1 - 0.00074 19.5 0.0 0.00092 19.2 0.0 1.3 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain Tcp11 PF05794.13 EGD88446.1 - 3.5e-104 349.4 0.1 3.5e-104 349.4 0.1 1.8 2 0 0 2 2 2 1 T-complex protein 11 PXA PF02194.15 EGD88447.2 - 1.1e-45 155.9 0.2 2.8e-45 154.5 0.2 1.8 1 0 0 1 1 1 1 PXA domain RGS PF00615.19 EGD88447.2 - 2.6e-11 43.8 0.0 5.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.32 EGD88449.1 - 4.7e-18 65.2 5.8 0.002 18.9 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD88449.1 - 2.7e-07 30.8 0.0 0.019 15.2 0.0 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGD88449.1 - 0.0054 15.7 0.6 0.1 11.6 0.0 2.7 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein tRNA-synt_1g PF09334.11 EGD88450.2 - 2.5e-149 497.3 0.0 4.5e-149 496.5 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGD88450.2 - 1.2e-07 30.4 0.0 5e-05 21.7 0.0 3.5 2 2 2 4 4 4 2 tRNA synthetases class I (I, L, M and V) BRF1 PF07741.13 EGD88450.2 - 0.32 11.4 7.8 0.81 10.1 7.8 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Laminin_EGF PF00053.24 EGD88450.2 - 0.37 11.0 3.8 0.66 10.2 3.8 1.4 1 0 0 1 1 1 0 Laminin EGF domain AP3D1 PF06375.11 EGD88450.2 - 0.56 10.4 7.8 0.96 9.7 7.8 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 PepSY PF03413.19 EGD88450.2 - 0.91 10.1 5.2 16 6.1 0.0 2.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Elongin_A PF06881.11 EGD88450.2 - 6.4 7.4 8.7 4.3 7.9 5.9 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Yae1_N PF09811.9 EGD88451.1 - 4.8e-07 29.4 3.6 7.4e-07 28.8 3.6 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal WD40 PF00400.32 EGD88452.1 - 7.5e-32 108.9 16.4 2.6e-08 34.4 0.1 8.0 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD88452.1 - 8.7e-12 45.2 5.2 0.0061 16.8 0.2 4.8 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGD88452.1 - 0.077 12.0 0.2 0.21 10.6 0.2 1.6 2 0 0 2 2 2 0 Coatomer WD associated region bZIP_2 PF07716.15 EGD88454.1 - 0.00014 21.8 9.2 0.00027 20.9 9.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EGD88454.1 - 0.0018 18.3 10.4 0.019 15.1 5.7 2.3 1 1 1 2 2 2 2 bZIP transcription factor DUF2796 PF10986.8 EGD88454.1 - 0.059 13.3 0.1 0.083 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Dicty_REP PF05086.12 EGD88454.1 - 0.92 7.4 3.8 1.2 7.0 3.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RRM_1 PF00076.22 EGD88455.1 - 6.7e-23 80.3 0.0 9e-23 79.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGD88455.1 - 0.00063 19.8 0.0 0.0012 18.9 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 EGD88455.1 - 0.08 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif ChaC PF04752.12 EGD88456.2 - 3.4e-53 180.4 0.0 4e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein EF-hand_1 PF00036.32 EGD88457.2 - 2.1e-20 70.7 5.5 6.4e-07 28.5 0.1 4.7 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGD88457.2 - 1.3e-17 62.1 4.1 0.00099 18.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGD88457.2 - 2.8e-17 62.3 8.0 2.4e-09 36.9 0.1 4.6 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_7 PF13499.6 EGD88457.2 - 6.2e-17 61.8 3.4 1e-07 32.3 0.0 3.4 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGD88457.2 - 3.5e-15 54.7 7.2 8.4e-05 21.9 0.4 4.7 4 1 0 4 4 4 4 EF hand EF-hand_14 PF17959.1 EGD88457.2 - 0.065 13.6 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain G6PD_C PF02781.16 EGD88458.2 - 1.7e-114 381.9 0.0 2.7e-114 381.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EGD88458.2 - 4e-61 206.7 0.0 9.1e-61 205.6 0.0 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain eIF-4B PF06273.11 EGD88459.1 - 0.0071 15.5 3.5 0.0078 15.3 3.5 1.3 1 0 0 1 1 1 1 Plant specific eukaryotic initiation factor 4B RhlB PF12300.8 EGD88459.1 - 4.6 7.4 10.6 5.6 7.1 10.6 1.3 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB MFS_1 PF07690.16 EGD88460.2 - 1.2e-05 24.4 22.1 7.1e-05 21.9 21.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGD88460.2 - 0.00046 18.7 2.9 0.00046 18.7 2.9 1.8 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CBS PF00571.28 EGD88462.1 - 0.0001 22.6 0.0 4.2 7.9 0.0 3.3 1 1 2 3 3 3 3 CBS domain Mito_carr PF00153.27 EGD88463.2 - 2.8e-47 158.6 6.6 2.9e-19 68.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SnoaL_2 PF12680.7 EGD88464.1 - 0.11 13.2 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain Peptidase_S10 PF00450.22 EGD88465.1 - 3.4e-113 379.2 0.0 4.2e-113 378.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_Me_trans PF04252.13 EGD88466.1 - 3.2e-78 261.9 0.0 3.6e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.17 EGD88467.1 - 3.6e-28 97.5 0.3 7.5e-28 96.5 0.3 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region ICE2 PF08426.10 EGD88468.1 - 2.3e-150 501.2 16.9 2.6e-150 501.1 16.9 1.0 1 0 0 1 1 1 1 ICE2 TFR_dimer PF04253.15 EGD88470.1 - 1.1e-30 106.2 0.0 2e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EGD88470.1 - 2e-19 70.0 0.0 5.9e-19 68.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 EGD88470.1 - 1.3e-09 37.9 0.1 3.7e-09 36.5 0.1 1.8 1 1 0 1 1 1 1 PA domain zf-C2H2_4 PF13894.6 EGD88471.1 - 0.00032 21.3 2.0 0.0075 17.0 0.1 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGD88471.1 - 0.00069 19.9 5.1 0.012 16.1 0.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type Ima1_N PF09779.9 EGD88471.1 - 0.074 13.9 0.4 0.21 12.4 0.4 1.9 1 1 0 1 1 1 0 Ima1 N-terminal domain IHABP4_N PF16174.5 EGD88471.1 - 8.9 6.9 13.5 1.8 9.2 3.9 2.5 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Fungal_trans PF04082.18 EGD88477.2 - 8.4e-16 57.8 0.0 1.4e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.21 EGD88480.1 - 4.7e-19 68.8 0.0 6.6e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGD88480.1 - 0.011 14.6 0.0 0.052 12.3 0.0 1.8 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase DUF4551 PF15087.6 EGD88482.2 - 0.21 10.4 0.2 0.26 10.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pkinase PF00069.25 EGD88483.2 - 2.7e-62 210.5 0.1 1.5e-31 109.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD88483.2 - 5.6e-29 101.2 0.1 3.9e-28 98.5 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Methyltransf_8 PF05148.15 EGD88484.1 - 5e-58 196.5 0.3 1.1e-53 182.3 0.0 2.8 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EGD88484.1 - 2.6e-07 31.2 0.0 1.2e-06 29.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD88484.1 - 7.7e-06 26.5 0.0 0.00045 20.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGD88484.1 - 0.0066 16.4 0.0 0.025 14.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD88484.1 - 0.025 14.4 0.0 5.9 6.7 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Proteasome PF00227.26 EGD88485.1 - 1.2e-56 191.2 0.1 1.6e-56 190.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGD88485.1 - 1.5e-12 47.0 0.2 3.6e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 EGD88486.2 - 5.5e-61 206.9 0.0 9.9e-61 206.0 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGD88486.2 - 8e-61 206.2 5.5 8e-61 206.2 5.5 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal DUF3346 PF11826.8 EGD88486.2 - 0.098 12.4 0.3 0.16 11.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) KH_8 PF17903.1 EGD88487.1 - 7.4e-30 102.9 0.0 1.9e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain Methyltransf_25 PF13649.6 EGD88488.1 - 5.6e-13 49.4 0.0 1.9e-12 47.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD88488.1 - 6.4e-12 46.0 0.0 1.3e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD88488.1 - 7.6e-12 45.4 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD88488.1 - 1.6e-07 32.0 0.0 4e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD88488.1 - 9.3e-07 28.8 0.2 5.1e-06 26.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EGD88488.1 - 5.4e-05 22.6 0.0 0.004 16.5 0.0 2.5 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EGD88488.1 - 0.00012 21.6 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 EGD88488.1 - 0.002 17.5 0.0 0.0037 16.6 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EGD88488.1 - 0.22 11.1 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain adh_short PF00106.25 EGD88489.1 - 7.2e-40 136.5 0.0 9.5e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD88489.1 - 3.9e-23 82.2 0.0 5.2e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD88489.1 - 2.4e-06 27.6 0.0 3.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGD88489.1 - 0.00081 18.6 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EGD88489.1 - 0.0011 18.5 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGD88489.1 - 0.072 12.5 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EGD88489.1 - 0.14 12.1 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Erg28 PF03694.13 EGD88490.1 - 1e-42 145.0 3.8 1.3e-42 144.7 3.8 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.22 EGD88491.2 - 2.8e-68 230.0 0.1 3.3e-67 226.5 0.0 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EGD88491.2 - 2.6e-48 163.9 0.1 7.6e-48 162.4 0.0 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 EGD88491.2 - 0.0053 15.6 0.0 0.24 10.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4921) DcpS_C PF11969.8 EGD88491.2 - 0.038 14.5 0.0 0.099 13.1 0.0 1.7 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding WG_beta_rep PF14903.6 EGD88491.2 - 0.17 12.2 0.1 0.48 10.8 0.1 1.8 1 0 0 1 1 1 0 WG containing repeat Fungal_trans_2 PF11951.8 EGD88495.2 - 1.5e-14 53.7 1.0 2.4e-14 53.0 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD88495.2 - 5.7e-07 29.5 11.9 5.7e-07 29.5 11.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp_protease PF09668.10 EGD88496.2 - 1.1e-50 170.5 0.6 1.5e-50 170.2 0.6 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGD88496.2 - 4.6e-23 81.6 0.0 7.3e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGD88496.2 - 1.1e-10 42.1 0.0 2.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.31 EGD88496.2 - 1.8e-07 30.9 0.0 2.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 EGD88496.2 - 0.0013 18.5 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain RVP_2 PF08284.11 EGD88496.2 - 0.0022 17.8 0.1 0.0053 16.5 0.1 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 EGD88496.2 - 0.014 15.7 0.0 0.035 14.4 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease NAD_binding_7 PF13241.6 EGD88496.2 - 0.09 13.2 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Cytadhesin_P30 PF07271.11 EGD88496.2 - 9.2 5.7 11.9 13 5.3 11.9 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Acetyltransf_10 PF13673.7 EGD88498.2 - 3.9e-12 46.2 0.0 6.2e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGD88498.2 - 3.1e-10 40.3 0.0 4.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGD88498.2 - 1.9e-07 31.4 0.0 3.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD88498.2 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DNA_pol_phi PF04931.13 EGD88498.2 - 0.048 11.8 0.8 0.06 11.5 0.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Acetyltransf_CG PF14542.6 EGD88498.2 - 0.12 12.5 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pox_Ag35 PF03286.14 EGD88498.2 - 0.16 11.7 0.6 0.26 11.0 0.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Acetyltransf_4 PF13420.7 EGD88498.2 - 0.25 11.4 0.0 0.38 10.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2457 PF10446.9 EGD88498.2 - 0.73 8.9 6.3 1 8.4 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 EGD88498.2 - 1.3 9.4 9.3 2.6 8.5 9.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOG1_N PF17835.1 EGD88499.2 - 2.7e-47 160.7 1.3 4.3e-47 160.1 0.1 2.0 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EGD88499.2 - 2.8e-28 97.6 1.7 6.7e-28 96.4 1.7 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EGD88499.2 - 5.8e-26 90.0 0.5 1.3e-25 88.9 0.5 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EGD88499.2 - 1.3e-15 57.5 0.0 3.2e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGD88499.2 - 8.5e-08 31.9 0.1 3.2e-07 30.0 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGD88499.2 - 0.00024 21.1 0.3 0.059 13.3 0.0 3.1 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 EGD88499.2 - 0.0059 16.7 0.1 1.8 8.6 0.0 2.8 1 1 1 2 2 2 1 Dynamin family AAA_16 PF13191.6 EGD88499.2 - 0.027 14.8 0.9 0.16 12.3 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 EGD88499.2 - 0.18 12.0 0.0 1 9.6 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase E1_DerP2_DerF2 PF02221.15 EGD88500.1 - 5.1e-26 91.7 0.1 6.1e-26 91.4 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EGD88500.1 - 0.00056 20.3 0.0 0.00097 19.5 0.0 1.5 1 1 0 1 1 1 1 ML-like domain GluR_Homer-bdg PF10606.9 EGD88500.1 - 0.021 15.0 0.4 0.044 14.0 0.4 1.5 1 0 0 1 1 1 0 Homer-binding domain of metabotropic glutamate receptor Glyco_hydro_61 PF03443.14 EGD88500.1 - 0.035 14.0 0.0 0.058 13.3 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 ATP-synt_F PF01990.17 EGD88501.1 - 2.3e-33 114.3 0.0 2.7e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PIN_8 PF18476.1 EGD88501.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 PIN like domain DUF2418 PF10332.9 EGD88502.1 - 1.4e-34 118.5 0.2 3.3e-34 117.3 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) MTHFR PF02219.17 EGD88504.1 - 1.2e-115 385.8 0.0 1.8e-115 385.2 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1804 PF08822.11 EGD88504.1 - 0.06 13.3 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Pribosyltran PF00156.27 EGD88505.1 - 2.4e-14 53.2 0.2 3.9e-14 52.5 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Aconitase PF00330.20 EGD88506.2 - 6.3e-146 487.0 0.2 8.4e-146 486.6 0.2 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGD88506.2 - 6.3e-40 136.5 0.0 1.4e-39 135.4 0.0 1.6 2 0 0 2 2 2 1 Aconitase C-terminal domain Glycos_transf_4 PF00953.21 EGD88507.1 - 2.6e-33 115.3 11.0 2.6e-33 115.3 11.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 4 DUF2070 PF09843.9 EGD88507.1 - 9.7 4.3 11.9 8.2 4.6 10.5 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) WD40 PF00400.32 EGD88508.1 - 2.2e-13 50.4 10.7 0.00094 20.0 0.6 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Myb_DNA-binding PF00249.31 EGD88511.2 - 6.1e-10 39.1 0.0 1.9e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EGD88511.2 - 1.8e-08 34.0 4.6 3.3e-08 33.2 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 EGD88511.2 - 0.0026 18.0 0.0 0.0078 16.5 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain PG_binding_1 PF01471.18 EGD88511.2 - 0.026 14.7 0.0 0.089 13.0 0.0 1.9 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF5112 PF17139.4 EGD88511.2 - 0.062 12.8 0.7 0.095 12.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) Pkinase PF00069.25 EGD88512.2 - 5.7e-70 235.7 0.0 7e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD88512.2 - 2.6e-33 115.4 0.0 3.6e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGD88512.2 - 1.2e-10 41.9 0.2 2.4e-10 41.0 0.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGD88512.2 - 2.6e-06 26.6 0.0 3.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGD88512.2 - 0.0049 16.2 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C2 PF00168.30 EGD88512.2 - 0.022 15.1 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 C2 domain APH PF01636.23 EGD88512.2 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ETC_C1_NDUFA5 PF04716.14 EGD88514.1 - 1.8e-27 94.9 1.4 4.7e-25 87.2 0.1 2.6 2 0 0 2 2 2 2 ETC complex I subunit conserved region Thioredoxin PF00085.20 EGD88515.2 - 2e-40 136.9 0.1 3.6e-24 84.7 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 EGD88515.2 - 2.3e-10 40.7 0.0 8.3e-05 22.6 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGD88515.2 - 0.0014 18.9 0.0 0.6 10.5 0.0 3.7 3 1 0 3 3 3 1 Thioredoxin-like HyaE PF07449.11 EGD88515.2 - 0.0015 18.5 0.0 0.65 10.0 0.0 2.7 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 EGD88515.2 - 0.0053 17.2 1.1 1.3 9.5 0.1 3.5 3 2 0 3 3 3 1 Thioredoxin-like domain TraF PF13728.6 EGD88515.2 - 0.035 13.9 7.7 0.4 10.5 0.0 3.7 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EGD88515.2 - 0.065 13.4 1.6 0.3 11.3 0.1 2.8 3 0 0 3 3 3 0 Thioredoxin-like Thioredoxin_3 PF13192.6 EGD88515.2 - 0.093 12.8 0.9 0.57 10.3 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin domain DAO PF01266.24 EGD88516.1 - 3.4e-31 109.1 0.6 5.1e-31 108.5 0.6 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGD88516.1 - 0.0018 18.5 0.0 0.0062 16.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 EGD88516.1 - 0.005 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family Pyr_redox_3 PF13738.6 EGD88516.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGD88516.1 - 0.019 14.1 1.4 0.055 12.5 1.4 1.7 1 1 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 EGD88516.1 - 0.052 13.6 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 EGD88516.1 - 0.057 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGD88516.1 - 0.075 12.1 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EGD88516.1 - 0.076 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EGD88516.1 - 0.087 12.8 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 EGD88516.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 EGD88516.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.16 EGD88517.2 - 1.8e-12 46.9 12.2 2.1e-12 46.7 12.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD88517.2 - 0.0044 16.0 7.0 0.0054 15.7 7.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter HNH_2 PF13391.6 EGD88518.1 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Na_Ca_ex PF01699.24 EGD88520.2 - 5.5e-34 117.3 38.6 5.9e-22 78.2 15.3 3.1 3 0 0 3 3 3 3 Sodium/calcium exchanger protein Cyt_bd_oxida_II PF02322.15 EGD88520.2 - 0.0027 17.1 10.5 0.027 13.8 3.2 2.3 2 0 0 2 2 2 2 Cytochrome bd terminal oxidase subunit II DUF2157 PF09925.9 EGD88520.2 - 1 9.2 6.1 2.3 8.0 0.4 3.2 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) Ribosomal_S7 PF00177.21 EGD88521.2 - 1.6e-29 102.5 0.0 2.5e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF1013 PF06242.11 EGD88521.2 - 0.0048 16.9 0.6 0.14 12.2 0.2 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1013) Peptidase_S28 PF05577.12 EGD88523.1 - 6.9e-53 180.0 0.1 3.5e-52 177.7 0.1 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EGD88523.1 - 0.041 13.4 0.1 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family SPX PF03105.19 EGD88524.2 - 8.5e-42 144.4 0.5 7.7e-29 101.8 0.1 2.1 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 EGD88524.2 - 3.6e-29 102.1 37.6 5.3e-29 101.6 37.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EGD88524.2 - 2.7e-25 89.2 37.5 2.7e-25 89.2 37.5 1.7 2 0 0 2 2 2 1 Citrate transporter DUF4220 PF13968.6 EGD88524.2 - 0.022 14.2 0.3 0.022 14.2 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) Ribonuclease_T2 PF00445.18 EGD88525.2 - 1.4e-15 58.0 6.0 1.9e-12 47.8 2.3 2.6 2 1 1 3 3 3 2 Ribonuclease T2 family Ribosomal_S8e PF01201.22 EGD88526.1 - 1.8e-55 186.9 1.3 2.1e-55 186.7 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SET PF00856.28 EGD88527.1 - 1.8 8.9 7.3 3.3 8.1 7.3 1.6 1 1 0 1 1 1 0 SET domain NmrA PF05368.13 EGD88528.1 - 1.8e-16 60.4 0.0 4.4e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 EGD88528.1 - 2.8e-07 30.6 0.0 6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_hydro_20 PF00728.22 EGD88529.1 - 1.3e-98 330.7 0.0 1.6e-98 330.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGD88529.1 - 3.4e-24 86.1 0.0 1.1e-23 84.4 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGD88529.1 - 0.00012 22.9 0.0 0.00024 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DOCK_N PF16172.5 EGD88530.1 - 1.2e-111 373.3 0.0 2.4e-111 372.3 0.0 1.5 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 EGD88530.1 - 1.9e-40 138.8 0.0 5.5e-40 137.3 0.0 1.8 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 EGD88530.1 - 1.2e-38 133.1 5.1 3.3e-38 131.6 5.1 1.6 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 EGD88530.1 - 0.00011 21.7 0.0 0.00029 20.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGD88530.1 - 0.00036 20.3 0.0 0.0044 16.9 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain PRIMA1 PF16101.5 EGD88530.1 - 9.3 6.3 8.0 30 4.7 8.0 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Sec3-PIP2_bind PF15277.6 EGD88531.1 - 1.9e-29 101.6 0.1 4e-29 100.6 0.1 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.9 EGD88531.1 - 2.5e-24 85.7 1.7 4e-24 85.0 1.7 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 SRP40_C PF05022.12 EGD88532.1 - 2.3e-18 66.8 0.1 9.2e-18 64.9 0.1 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain F-box-like PF12937.7 EGD88533.1 - 2.5e-07 30.5 0.9 6.6e-07 29.1 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD88533.1 - 1.8e-05 24.5 0.1 4.1e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain p450 PF00067.22 EGD88535.2 - 1.2e-45 156.2 0.0 3.2e-45 154.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Hit1_C PF18268.1 EGD88536.2 - 0.15 12.2 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Hit1 C-terminal DUF1992 PF09350.10 EGD88537.1 - 2.2e-19 69.4 0.1 6.9e-19 67.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) RPAP1_N PF08621.10 EGD88537.1 - 0.0044 16.7 0.2 1.4 8.8 0.0 3.2 2 0 0 2 2 2 2 RPAP1-like, N-terminal Lyase_N PF09092.11 EGD88537.1 - 0.016 15.1 0.2 0.077 12.9 0.1 2.0 2 0 0 2 2 2 0 Lyase, N terminal SpoIIIAC PF06686.11 EGD88538.1 - 0.5 10.6 3.0 0.57 10.4 0.3 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family CENP_C_N PF15622.6 EGD88539.2 - 0.071 12.6 2.3 0.1 12.1 2.3 1.2 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal Acetyltransf_8 PF13523.6 EGD88543.2 - 2.3e-25 89.0 0.0 3.4e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zn-ribbon_14 PF16503.5 EGD88544.1 - 1.5e-18 66.0 5.4 1.5e-18 66.0 5.4 3.6 4 0 0 4 4 4 1 Zinc-ribbon ATP_bind_3 PF01171.20 EGD88544.1 - 2.3e-18 66.6 0.0 3.6e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 EGD88544.1 - 0.032 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.20 EGD88544.1 - 0.46 10.7 6.0 2.1 8.6 0.6 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) RecR PF02132.15 EGD88544.1 - 1.8 8.2 10.2 0.054 13.1 1.6 2.6 3 0 0 3 3 3 0 RecR protein SBF PF01758.16 EGD88545.1 - 1.8e-52 177.9 12.9 1.8e-52 177.9 12.9 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF1240 PF06836.12 EGD88545.1 - 6.3 7.4 7.6 0.57 10.8 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1240) DUF521 PF04412.13 EGD88546.2 - 0.085 11.5 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Cyclin_N PF00134.23 EGD88548.1 - 1.7e-11 43.9 0.0 4.2e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGD88548.1 - 4.3e-05 23.9 0.0 9.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Cyclin Complex1_LYR_2 PF13233.6 EGD88549.1 - 1.3e-22 80.3 0.4 1.5e-22 80.1 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like CHD5 PF04420.14 EGD88549.1 - 0.026 14.4 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 CHD5-like protein PTase_Orf2 PF11468.8 EGD88549.1 - 0.15 11.5 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Aromatic prenyltransferase Orf2 NifU PF01106.17 EGD88555.1 - 1.6e-25 89.0 0.0 4.1e-25 87.7 0.0 1.6 2 0 0 2 2 2 1 NifU-like domain Nfu_N PF08712.11 EGD88555.1 - 3.1e-25 88.1 0.0 7.8e-25 86.8 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal PSP1 PF04468.12 EGD88558.1 - 1.5e-28 98.9 2.6 2.4e-28 98.3 2.6 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF2570 PF10828.8 EGD88558.1 - 7.2 6.5 6.3 2.2 8.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Cornichon PF03311.14 EGD88559.2 - 1.4e-40 138.4 8.8 1.7e-40 138.1 8.8 1.1 1 0 0 1 1 1 1 Cornichon protein MFS_1 PF07690.16 EGD88560.1 - 8.8e-19 67.6 35.6 8.8e-19 67.6 35.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EGD88560.1 - 5.3e-06 25.1 4.7 1.1e-05 24.0 4.7 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector TerC PF03741.16 EGD88560.1 - 0.012 15.4 0.4 0.012 15.4 0.4 2.6 2 1 0 2 2 2 0 Integral membrane protein TerC family Ferlin_C PF16165.5 EGD88560.1 - 0.04 13.9 0.3 0.097 12.6 0.0 1.8 2 0 0 2 2 2 0 Ferlin C-terminus ABC2_membrane PF01061.24 EGD88561.2 - 2.2e-39 135.0 18.7 3.9e-39 134.3 18.7 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGD88561.2 - 5e-27 95.1 0.1 9.7e-27 94.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGD88561.2 - 2.4e-06 27.6 0.0 0.055 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGD88561.2 - 4.7e-06 25.9 22.5 0.00015 21.0 22.4 3.2 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 EGD88561.2 - 0.0053 16.5 0.2 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EGD88561.2 - 0.014 15.9 0.1 0.027 15.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EGD88561.2 - 0.018 14.5 0.1 0.089 12.2 0.1 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGD88561.2 - 0.018 15.0 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EGD88561.2 - 0.028 15.0 0.0 0.094 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGD88561.2 - 0.031 14.5 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGD88561.2 - 0.032 14.5 0.0 0.085 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGD88561.2 - 0.035 13.7 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGD88561.2 - 0.059 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 EGD88561.2 - 0.075 12.7 0.1 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 EGD88561.2 - 0.14 11.8 0.0 0.6 9.7 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 EGD88561.2 - 0.18 12.0 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.21 EGD88562.1 - 1.2e-42 146.4 0.0 1.6e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGD88562.1 - 1.7e-06 26.8 0.0 2.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGD88562.1 - 2e-06 27.0 0.0 3.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGD88562.1 - 3.4e-06 26.6 0.0 5.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGD88562.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Peptidase_M36 PF02128.15 EGD88564.1 - 8.2e-158 525.4 11.5 1.2e-157 524.8 11.5 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGD88564.1 - 4.2e-16 58.5 4.2 9.2e-16 57.4 4.2 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EGD88564.1 - 0.0006 19.7 0.0 0.002 18.0 0.0 2.0 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain AMP-binding PF00501.28 EGD88565.2 - 2.5e-32 112.0 0.0 4.2e-32 111.3 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD88565.2 - 2e-07 31.9 0.0 4.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lyase_1 PF00206.20 EGD88566.1 - 1.6e-85 287.2 0.0 2.4e-85 286.7 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EGD88566.1 - 4.1e-23 81.9 0.0 1e-22 80.6 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal CNOT1_HEAT PF16418.5 EGD88566.1 - 0.096 12.8 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Sulfatase PF00884.23 EGD88568.2 - 3.6e-11 43.0 0.1 7.2e-11 42.0 0.1 1.5 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 EGD88568.2 - 0.045 13.3 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase JmjC PF02373.22 EGD88570.2 - 1e-07 32.4 0.0 2.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 EGD88570.2 - 2.5e-05 24.4 12.5 2.5e-05 24.4 12.5 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 ZZ PF00569.17 EGD88570.2 - 8.6e-05 22.3 8.0 8.6e-05 22.3 8.0 2.8 2 1 0 2 2 2 1 Zinc finger, ZZ type Baculo_IE-1 PF05290.11 EGD88570.2 - 0.15 12.0 9.4 0.069 13.1 2.3 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Cupin_2 PF07883.11 EGD88570.2 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Polyketide_cyc PF03364.20 EGD88572.1 - 1.1e-19 71.0 0.0 2.1e-19 70.0 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Sod_Fe_C PF02777.18 EGD88573.2 - 2.2e-18 66.3 0.0 9.1e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain PIG-S PF10510.9 EGD88575.1 - 3.4e-174 580.5 6.2 4.3e-174 580.1 6.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein ANAPC4_WD40 PF12894.7 EGD88576.1 - 7.4e-06 26.2 0.0 0.002 18.4 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain TLP-20 PF06088.11 EGD88576.1 - 0.017 15.0 1.9 0.026 14.4 1.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.14 EGD88576.1 - 0.12 10.7 6.1 0.16 10.2 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 EGD88576.1 - 1.5 9.8 7.6 1.3e+02 3.7 0.3 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat NOA36 PF06524.12 EGD88576.1 - 1.6 8.0 8.2 2.4 7.4 8.2 1.2 1 0 0 1 1 1 0 NOA36 protein PQQ_3 PF13570.6 EGD88576.1 - 1.7 9.3 6.2 4 8.1 0.1 3.9 3 1 1 4 4 4 0 PQQ-like domain Med19 PF10278.9 EGD88576.1 - 2.7 7.9 8.4 73 3.2 9.1 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Diphthamide_syn PF01866.17 EGD88577.1 - 1.3e-84 284.2 0.0 2.6e-84 283.2 0.0 1.5 1 1 0 1 1 1 1 Putative diphthamide synthesis protein DUF1923 PF09083.10 EGD88577.1 - 0.18 11.5 0.1 19 5.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) Methyltransf_12 PF08242.12 EGD88580.1 - 1e-15 58.3 0.0 4.6e-15 56.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD88580.1 - 5.5e-14 52.6 0.0 1.2e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD88580.1 - 5e-12 46.3 0.0 1.2e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD88580.1 - 5.7e-11 42.5 0.0 1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD88580.1 - 1.3e-08 34.8 0.0 2.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD88580.1 - 3.5e-05 23.2 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 EGD88580.1 - 0.00011 21.5 0.0 0.015 14.5 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_24 PF13578.6 EGD88580.1 - 0.0011 20.0 0.0 0.0026 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGD88580.1 - 0.0016 18.1 0.1 0.0026 17.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EGD88580.1 - 0.0067 16.2 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase CMAS PF02353.20 EGD88580.1 - 0.055 12.8 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 EGD88580.1 - 0.067 13.0 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase DUF3419 PF11899.8 EGD88580.1 - 0.079 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) TehB PF03848.14 EGD88580.1 - 0.084 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 EGD88580.1 - 0.094 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HlyIII PF03006.20 EGD88582.1 - 2.9e-61 207.1 22.1 3.5e-61 206.8 22.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Asr PF06392.11 EGD88582.1 - 0.043 14.2 0.7 0.082 13.3 0.7 1.4 1 0 0 1 1 1 0 Acid shock protein repeat GlnD_UR_UTase PF08335.11 EGD88582.1 - 0.4 10.8 5.3 1.5 8.9 0.8 2.2 1 1 0 2 2 2 0 GlnD PII-uridylyltransferase FmiP_Thoc5 PF09766.9 EGD88583.2 - 9.9e-30 104.0 12.6 1.4e-29 103.6 12.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 EGD88583.2 - 0.012 15.7 7.3 0.024 14.7 3.7 2.4 3 0 0 3 3 3 0 Spermatogenesis-associated C-terminus Casc1_N PF15927.5 EGD88583.2 - 0.057 13.1 13.2 0.18 11.5 7.2 2.5 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus DUF948 PF06103.11 EGD88583.2 - 0.084 13.1 0.8 0.94 9.8 0.0 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.6 EGD88583.2 - 0.11 12.9 12.4 0.16 12.3 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) YabA PF06156.13 EGD88583.2 - 0.5 11.0 7.0 2.3 8.9 0.3 2.6 2 1 0 2 2 2 0 Initiation control protein YabA DUF4140 PF13600.6 EGD88583.2 - 1.2 9.6 8.0 6 7.4 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 EGD88583.2 - 1.2 9.7 19.4 1.3 9.5 8.5 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region Atg14 PF10186.9 EGD88583.2 - 3.7 6.6 15.2 4.3 6.3 10.9 2.4 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF349 PF03993.12 EGD88583.2 - 3.8 7.9 11.0 0.56 10.5 5.8 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DIE2_ALG10 PF04922.12 EGD88584.2 - 2.7e-57 194.8 0.1 3.4e-57 194.5 0.1 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Sld5 PF05916.11 EGD88585.2 - 1.4e-32 112.4 0.0 3.4e-32 111.1 0.0 1.6 1 1 0 1 1 1 1 GINS complex protein CUE PF02845.16 EGD88586.2 - 4.3e-10 39.1 0.0 6.7e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 EGD88586.2 - 0.01 15.4 10.6 0.019 14.6 10.6 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) SMC_N PF02463.19 EGD88587.2 - 3.3e-46 157.5 0.0 1.1e-45 155.8 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGD88587.2 - 2.8e-20 72.8 1.3 1.8e-19 70.2 0.4 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGD88587.2 - 0.00016 21.6 0.5 0.00054 19.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system GAS PF13851.6 EGD88587.2 - 0.0035 16.7 6.7 0.0035 16.7 6.7 7.3 2 2 5 7 7 7 2 Growth-arrest specific micro-tubule binding HSBP1 PF06825.12 EGD88587.2 - 5.4 6.9 19.2 0.074 12.9 0.6 5.4 5 0 0 5 5 5 0 Heat shock factor binding protein 1 GDI PF00996.18 EGD88588.1 - 3.3e-191 635.5 0.0 4.2e-191 635.2 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EGD88588.1 - 0.028 14.6 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.13 EGD88589.1 - 1.2e-19 70.2 0.1 2e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) NOT2_3_5 PF04153.18 EGD88590.2 - 3.6e-27 95.0 0.1 3.6e-27 95.0 0.1 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family BORG_CEP PF14957.6 EGD88590.2 - 0.15 13.3 11.4 0.94 10.7 6.2 2.3 2 0 0 2 2 2 0 Cdc42 effector CCDC53 PF10152.9 EGD88590.2 - 1.4 9.3 14.5 0.11 13.0 5.7 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex 4HBT PF03061.22 EGD88591.1 - 7.3e-14 51.9 0.1 1.1e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EGD88591.1 - 6e-06 26.7 0.0 1e-05 25.9 0.0 1.4 2 0 0 2 2 2 1 Thioesterase-like superfamily CDC73_C PF05179.14 EGD88592.1 - 1.9e-58 196.6 0.0 3e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal RGS PF00615.19 EGD88593.2 - 6.3e-22 78.1 0.0 7.7e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF1304 PF06993.12 EGD88593.2 - 0.19 11.7 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) ORC4_C PF14629.6 EGD88595.1 - 1.4e-44 152.1 0.0 2.3e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EGD88595.1 - 1.5e-18 67.8 0.1 3.8e-18 66.5 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGD88595.1 - 2.1e-05 24.8 0.0 6.9e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGD88595.1 - 0.00016 20.9 0.0 0.00028 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA PF00004.29 EGD88595.1 - 0.0004 20.8 0.0 0.0014 19.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGD88595.1 - 0.0022 18.4 0.7 0.0072 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGD88595.1 - 0.0052 16.7 0.2 0.031 14.2 0.2 2.2 1 1 0 1 1 1 1 NACHT domain AAA_5 PF07728.14 EGD88595.1 - 0.045 13.8 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGD88595.1 - 0.061 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EGD88595.1 - 0.073 12.4 0.1 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.6 EGD88595.1 - 0.15 12.1 0.1 0.51 10.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGD88595.1 - 0.18 11.7 0.0 0.87 9.5 0.0 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Dicty_REP PF05086.12 EGD88595.1 - 5.8 4.8 7.4 9.3 4.1 7.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SET PF00856.28 EGD88596.1 - 3e-06 27.7 5.7 5.7e-06 26.8 1.0 3.1 2 1 0 2 2 2 1 SET domain PHD PF00628.29 EGD88596.1 - 5.4e-06 26.2 9.6 1.3e-05 24.9 9.6 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGD88596.1 - 0.46 10.1 5.4 0.85 9.2 5.4 1.4 1 0 0 1 1 1 0 PHD-finger ArfGap PF01412.18 EGD88598.1 - 1.3e-36 125.2 0.0 2.7e-36 124.2 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.31 EGD88598.1 - 0.11 12.4 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 UBA/TS-N domain Glyco_transf_22 PF03901.17 EGD88599.2 - 2.5e-18 66.5 2.1 3.1e-18 66.2 2.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.21 EGD88600.1 - 1.7e-116 389.2 0.0 2e-116 389.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EGD88600.1 - 0.017 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase ABC_membrane PF00664.23 EGD88602.2 - 3.2e-61 207.4 33.9 3.7e-39 135.0 19.3 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EGD88602.2 - 1.8e-47 161.3 1.6 3.8e-27 95.5 0.2 3.4 3 0 0 3 3 3 2 ABC transporter MMR_HSR1 PF01926.23 EGD88602.2 - 2.1e-06 27.8 1.0 0.018 15.1 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGD88602.2 - 5.6e-06 26.8 0.8 0.14 12.5 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EGD88602.2 - 2.7e-05 24.1 4.0 0.038 13.8 0.0 3.8 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGD88602.2 - 3.3e-05 23.4 6.9 0.22 10.9 3.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGD88602.2 - 7.6e-05 22.7 0.6 0.11 12.4 0.2 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EGD88602.2 - 0.00012 22.6 0.4 0.27 11.7 0.1 3.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGD88602.2 - 0.00042 20.0 1.3 0.35 10.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGD88602.2 - 0.00063 19.1 0.0 0.13 11.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MeaB PF03308.16 EGD88602.2 - 0.0019 17.2 2.2 0.38 9.7 0.2 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 EGD88602.2 - 0.002 17.9 0.2 1.5 8.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 EGD88602.2 - 0.0022 18.1 2.1 0.21 11.6 0.1 2.6 2 0 0 2 2 2 1 Dynamin family YqzM PF14141.6 EGD88602.2 - 0.0067 16.4 0.5 0.017 15.1 0.1 2.0 2 0 0 2 2 1 1 YqzM-like protein DUF87 PF01935.17 EGD88602.2 - 0.012 15.7 2.6 0.1 12.6 0.5 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 EGD88602.2 - 0.018 15.6 0.3 5.2 7.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGD88602.2 - 0.038 14.3 2.6 4.2 7.6 0.1 3.2 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EGD88602.2 - 0.04 13.6 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 EGD88602.2 - 0.058 13.6 0.1 21 5.3 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EGD88602.2 - 0.13 12.6 0.2 11 6.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 EGD88602.2 - 0.18 10.9 1.1 11 5.1 0.2 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 EGD88602.2 - 0.49 10.1 5.2 2.7 7.7 0.2 2.8 3 0 0 3 3 2 0 AAA domain Ploopntkinase3 PF18751.1 EGD88602.2 - 0.67 9.8 3.5 18 5.2 0.1 2.7 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 EGD88602.2 - 0.71 10.1 5.1 0.36 11.0 0.1 2.7 3 0 0 3 3 2 0 AAA domain AA_permease_2 PF13520.6 EGD88603.1 - 1.5e-58 198.7 53.4 2.1e-58 198.2 53.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD88603.1 - 2.9e-13 49.2 42.9 4.3e-13 48.7 42.9 1.2 1 0 0 1 1 1 1 Amino acid permease Tyr-DNA_phospho PF06087.12 EGD88604.2 - 1.4e-23 83.5 0.0 1.8e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase ACBP PF00887.19 EGD88605.1 - 4e-19 68.6 0.2 4.7e-19 68.4 0.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein U-box PF04564.15 EGD88606.1 - 6.2e-24 84.0 0.1 1.2e-23 83.0 0.1 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.6 EGD88606.1 - 1.1e-08 34.6 0.2 1.1e-08 34.6 0.2 1.9 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 EGD88606.1 - 4.3e-08 32.7 8.0 0.0002 21.2 1.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGD88606.1 - 4.6e-08 33.6 3.3 0.00013 22.5 0.0 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGD88606.1 - 2.9e-06 26.9 4.1 8.5e-05 22.2 1.5 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGD88606.1 - 3.2e-06 27.6 1.1 0.0012 19.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 EGD88606.1 - 1.2e-05 26.0 5.4 2.1e-05 25.2 5.4 1.4 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_14 PF13428.6 EGD88606.1 - 5.5e-05 23.7 0.2 0.46 11.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGD88606.1 - 7.1e-05 23.0 4.1 0.01 16.1 0.9 2.6 2 1 1 3 3 3 3 Tetratricopeptide repeat zf-Nse PF11789.8 EGD88606.1 - 0.0026 17.5 0.3 0.0079 16.0 0.3 1.9 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TPR_17 PF13431.6 EGD88606.1 - 0.004 17.4 2.3 0.092 13.2 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 EGD88606.1 - 0.0065 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EGD88606.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 RING-type zinc-finger TPR_10 PF13374.6 EGD88606.1 - 0.018 14.9 2.8 1.4 8.9 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGD88606.1 - 0.046 13.9 0.2 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FCH PF00611.23 EGD88606.1 - 0.057 13.7 0.1 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain TPR_4 PF07721.14 EGD88606.1 - 0.11 13.2 1.1 2.2 9.1 1.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGD88606.1 - 0.9 9.9 4.6 9.6 6.7 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGD88606.1 - 2.3 9.0 4.4 9.1 7.2 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TIM PF00121.18 EGD88609.1 - 2e-41 142.0 0.0 6.7e-41 140.3 0.0 1.8 1 1 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.18 EGD88610.1 - 1.6e-43 148.0 0.2 1.8e-43 147.9 0.2 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2620 PF10941.8 EGD88610.1 - 0.022 14.9 0.1 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2620 MCR_C PF04609.12 EGD88610.1 - 0.093 11.8 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C DHO_dh PF01180.21 EGD88611.1 - 1.2e-62 211.8 0.8 1.2e-54 185.6 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EGD88611.1 - 0.004 16.2 0.9 0.012 14.7 0.9 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.17 EGD88611.1 - 0.18 11.3 0.2 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 PcrB family Mnd1 PF03962.15 EGD88612.1 - 3.1e-21 75.4 0.1 1.1e-20 73.7 0.0 2.0 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 EGD88612.1 - 0.00076 19.5 0.3 0.0027 17.8 0.3 1.9 1 0 0 1 1 1 1 Leucine zipper with capping helix domain BRE1 PF08647.11 EGD88612.1 - 0.027 14.5 10.7 0.6 10.2 7.3 3.2 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 EGD88612.1 - 0.096 12.5 13.5 0.45 10.3 2.4 3.4 1 1 2 3 3 3 0 Septum formation initiator Lzipper-MIP1 PF14389.6 EGD88612.1 - 0.27 11.5 7.6 1.7 9.0 0.5 3.6 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 TSC22 PF01166.18 EGD88612.1 - 0.3 11.4 5.9 0.58 10.5 0.5 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family SlyX PF04102.12 EGD88612.1 - 0.51 11.0 5.8 1.9 9.2 1.2 2.9 2 1 0 2 2 2 0 SlyX Cnn_1N PF07989.11 EGD88612.1 - 0.77 9.9 9.4 20 5.4 8.4 2.9 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 LPP PF04728.13 EGD88612.1 - 1.1 9.7 3.8 20 5.7 0.1 2.7 3 0 0 3 3 2 0 Lipoprotein leucine-zipper TMCO5 PF14992.6 EGD88612.1 - 1.4 8.4 7.0 2.6 7.5 7.0 1.4 1 0 0 1 1 1 0 TMCO5 family BLOC1_2 PF10046.9 EGD88612.1 - 1.9 8.9 6.2 2.8 8.3 0.6 2.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1843 PF08898.10 EGD88612.1 - 2.3 8.8 4.7 14 6.3 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) FlxA PF14282.6 EGD88612.1 - 3.5 7.7 8.9 2.1e+02 2.0 9.1 2.7 1 1 0 1 1 1 0 FlxA-like protein bZIP_2 PF07716.15 EGD88612.1 - 3.6 7.8 9.2 7.9 6.7 1.6 3.2 2 1 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.6 EGD88612.1 - 4.8 6.4 6.2 16 4.8 6.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UAF_Rrn10 PF05234.11 EGD88613.2 - 9.4e-05 22.6 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 UAF complex subunit Rrn10 WD40 PF00400.32 EGD88614.1 - 2.1e-14 53.7 20.8 9.3e-05 23.1 1.7 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD88614.1 - 2.7e-12 46.8 0.6 0.0038 17.5 0.1 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGD88614.1 - 0.0014 18.3 0.1 0.0083 15.7 0.0 2.1 2 0 0 2 2 2 1 PQQ-like domain Fungal_trans_2 PF11951.8 EGD88615.1 - 7.8e-99 331.1 0.2 9.8e-99 330.8 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD88615.1 - 1.4e-06 28.3 8.8 2.9e-06 27.3 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 EGD88616.1 - 0.049 12.2 0.1 0.06 11.9 0.1 1.0 1 0 0 1 1 1 0 AMP-binding enzyme SAM_2 PF07647.17 EGD88620.2 - 2.9e-10 40.1 0.1 5.4e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGD88620.2 - 4.7e-08 33.4 0.9 8.4e-08 32.6 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 EGD88620.2 - 1.1e-07 32.3 0.4 5.5e-07 30.0 0.4 2.3 1 1 0 1 1 1 1 PH domain SAM_Ste50p PF09235.10 EGD88620.2 - 0.0074 16.5 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.16 EGD88620.2 - 0.033 14.2 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PH_6 PF15406.6 EGD88620.2 - 0.095 13.0 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain zf-H2C2_2 PF13465.6 EGD88624.2 - 4.3e-06 26.9 12.5 1.2e-05 25.5 1.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 EGD88624.2 - 0.0001 22.5 4.6 0.00021 21.5 4.6 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EGD88624.2 - 0.00012 22.6 15.0 0.013 16.2 5.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGD88624.2 - 0.00091 19.5 4.8 0.061 13.6 1.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EGD88624.2 - 0.017 15.5 14.5 0.089 13.3 7.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 EGD88624.2 - 0.37 11.2 5.0 3.3 8.2 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 EGD88624.2 - 8.6 6.1 6.3 36 4.1 0.6 3.4 3 0 0 3 3 3 0 MYST family zinc finger domain QCR10 PF09796.9 EGD88625.2 - 3.8e-25 87.7 0.1 6e-25 87.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) APG5 PF04106.12 EGD88626.1 - 1e-68 231.3 0.0 1.3e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 SelP_N PF04592.14 EGD88627.1 - 0.99 8.8 15.4 1.3 8.3 15.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region IER PF05760.12 EGD88627.1 - 1.1 9.5 10.5 1.4 9.2 10.5 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) Presenilin PF01080.17 EGD88627.1 - 1.7 7.4 2.9 1.8 7.3 2.9 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 EGD88627.1 - 6.2 5.2 12.9 7.3 5.0 12.9 1.1 1 0 0 1 1 1 0 Macoilin family FAM76 PF16046.5 EGD88627.1 - 9.8 5.4 6.0 12 5.1 6.0 1.1 1 0 0 1 1 1 0 FAM76 protein MFS_1 PF07690.16 EGD88628.1 - 5.3e-19 68.4 52.2 1.4e-17 63.6 45.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Arrestin_N PF00339.29 EGD88632.1 - 2.5e-15 56.8 0.0 4.8e-14 52.7 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGD88632.1 - 5.7e-05 23.6 0.2 0.04 14.4 0.0 3.5 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Helo_like_N PF17111.5 EGD88635.1 - 0.00055 19.4 2.9 0.00091 18.6 2.9 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SHR3_chaperone PF08229.11 EGD88636.2 - 1.6e-46 157.6 0.2 2e-46 157.3 0.2 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 Phage_holin_2_4 PF16082.5 EGD88636.2 - 0.032 13.9 1.6 0.058 13.1 1.6 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Ribosomal_60s PF00428.19 EGD88636.2 - 0.054 14.1 2.5 0.054 14.1 2.5 2.6 2 1 1 3 3 3 0 60s Acidic ribosomal protein Peptidase_M28 PF04389.17 EGD88642.2 - 1.1e-23 84.0 0.0 2.3e-23 82.9 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGD88642.2 - 0.00079 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4317 PF14199.6 EGD88642.2 - 0.077 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) Glyco_hydro81C PF17652.1 EGD88643.1 - 2.3e-164 546.7 2.6 2.9e-164 546.4 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EGD88643.1 - 5.7e-121 403.6 0.3 8.1e-121 403.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Utp14 PF04615.13 EGD88645.2 - 1.9e-207 691.4 61.1 1.9e-207 691.4 61.1 2.5 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.9 EGD88646.1 - 1.4e-12 47.4 0.2 1.9e-12 47.0 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF4899 PF16240.5 EGD88646.1 - 0.071 12.3 0.3 0.083 12.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) IQ PF00612.27 EGD88647.2 - 0.018 14.8 0.2 0.018 14.8 0.2 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif RRM_1 PF00076.22 EGD88649.1 - 4.5e-80 263.5 4.7 5.7e-22 77.3 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EGD88649.1 - 1.2e-26 92.7 0.1 5.4e-26 90.6 0.1 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EGD88649.1 - 4.3e-14 52.2 0.0 0.0098 15.5 0.0 5.3 2 1 3 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGD88649.1 - 1e-06 28.7 0.4 5.2 7.3 0.0 5.4 5 1 0 5 5 5 2 RNA recognition motif RRM_occluded PF16842.5 EGD88649.1 - 5.3e-06 26.2 0.0 0.017 15.0 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGD88649.1 - 0.0015 18.5 0.5 48 4.1 0.0 4.7 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGD88649.1 - 0.0021 18.0 13.3 0.17 11.9 2.2 4.9 5 0 0 5 5 5 1 RNA binding motif Limkain-b1 PF11608.8 EGD88649.1 - 0.015 15.3 1.0 4.6 7.4 0.0 3.5 3 0 0 3 3 3 0 Limkain b1 OB_RNB PF08206.11 EGD88649.1 - 0.11 12.2 1.8 17 5.2 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.8 EGD88649.1 - 0.23 12.0 7.3 1.4 9.5 0.9 3.1 3 0 0 3 3 3 0 Heat induced stress protein YflT RNA_pol_Rpc4 PF05132.14 EGD88649.1 - 6.7 7.1 11.6 17 5.8 8.6 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Herpes_BLLF1 PF05109.13 EGD88649.1 - 8.1 4.3 8.7 10 3.9 8.7 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Fe-ADH PF00465.19 EGD88650.2 - 1.2e-64 218.5 1.1 1.5e-64 218.1 1.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGD88650.2 - 1.1e-17 64.6 0.0 1.9e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase PFK PF00365.20 EGD88650.2 - 0.023 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase DAO PF01266.24 EGD88651.1 - 5.8e-61 207.0 0.0 6.5e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGD88651.1 - 0.00026 20.4 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGD88651.1 - 0.00031 20.9 0.6 0.00065 19.9 0.6 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGD88651.1 - 0.0065 15.7 0.0 0.017 14.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGD88651.1 - 0.014 14.7 0.2 0.053 12.8 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 EGD88651.1 - 0.016 14.4 0.3 0.052 12.8 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 EGD88651.1 - 0.027 15.0 0.3 0.052 14.1 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGD88651.1 - 0.033 14.2 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 EGD88651.1 - 0.071 13.4 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EGD88651.1 - 0.13 12.1 0.4 0.24 11.3 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EGD88651.1 - 0.14 11.4 0.1 0.52 9.5 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGD88651.1 - 0.17 10.9 2.2 0.31 10.1 2.2 1.3 1 0 0 1 1 1 0 FAD binding domain Vps52 PF04129.12 EGD88652.2 - 6.8e-58 196.6 0.8 8e-58 196.4 0.8 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family eIF-5a PF01287.20 EGD88653.1 - 7.2e-27 93.3 0.7 1e-26 92.8 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EGD88653.1 - 0.0027 17.7 0.2 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Lactamase_B_5 PF14597.6 EGD88653.1 - 0.069 12.6 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Ribosomal_L40e PF01020.17 EGD88655.2 - 4.6e-31 106.5 11.0 6.2e-31 106.1 11.0 1.2 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.23 EGD88655.2 - 1.5e-19 69.5 0.0 2.1e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGD88655.2 - 2.3e-05 24.1 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like AKAP_110 PF05716.13 EGD88655.2 - 0.12 10.6 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) Yip1 PF04893.17 EGD88656.1 - 1.6e-15 57.2 17.2 3.2e-15 56.3 17.2 1.5 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 EGD88656.1 - 0.11 11.9 5.9 0.19 11.2 3.2 2.2 1 1 0 2 2 2 0 YIF1 DUF5585 PF17823.1 EGD88656.1 - 0.33 9.9 0.1 0.48 9.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) DUF2070 PF09843.9 EGD88656.1 - 9.5 4.4 9.2 12 4.0 9.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RabGAP-TBC PF00566.18 EGD88657.1 - 1.1e-22 80.8 0.4 2.6e-22 79.5 0.2 1.7 2 1 1 3 3 3 1 Rab-GTPase-TBC domain MMS1_N PF10433.9 EGD88659.2 - 5.2e-89 299.1 0.0 7.9e-89 298.5 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGD88659.2 - 0.0015 17.9 0.0 0.0062 15.9 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region GTP_EFTU PF00009.27 EGD88660.1 - 3.5e-34 118.1 0.1 5.3e-33 114.2 0.1 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGD88660.1 - 7.2e-21 74.3 0.1 2.2e-20 72.8 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EGD88660.1 - 6.7e-10 39.2 4.5 7.9e-10 39.0 0.1 3.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EGD88660.1 - 2.3e-09 37.0 0.0 7.2e-09 35.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 EGD88660.1 - 5.2e-07 29.7 0.5 1e-05 25.5 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 EGD88660.1 - 0.00056 20.1 0.0 0.0019 18.4 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGD88660.1 - 0.006 16.4 0.0 0.029 14.2 0.0 2.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 EGD88660.1 - 0.051 13.2 0.0 0.25 10.9 0.0 2.3 1 1 0 1 1 1 0 Ras family Rhodanese PF00581.20 EGD88661.1 - 7.8e-09 36.0 0.0 1.9e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain p450 PF00067.22 EGD88662.1 - 4.1e-54 184.1 0.0 5.8e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase_6 PF18029.1 EGD88663.1 - 4.1e-05 24.3 0.1 7.8e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EGD88663.1 - 0.00099 19.3 0.0 0.01 16.0 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zf-HC2 PF13490.6 EGD88663.1 - 0.15 12.3 0.1 0.33 11.3 0.1 1.6 1 0 0 1 1 1 0 Putative zinc-finger SRP68 PF16969.5 EGD88664.2 - 3.3e-187 623.9 1.4 3.7e-187 623.7 1.4 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 MCM PF00493.23 EGD88666.2 - 7.2e-98 326.1 0.1 1.1e-97 325.6 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EGD88666.2 - 1.5e-24 86.2 0.6 6.7e-24 84.1 0.6 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_OB PF17207.3 EGD88666.2 - 4.6e-15 55.6 0.0 1.1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 EGD88666.2 - 5.5e-07 29.2 0.0 9.9e-06 25.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGD88666.2 - 0.0021 17.9 0.0 0.0049 16.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGD88666.2 - 0.068 12.9 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain PBP1_TM PF14812.6 EGD88666.2 - 0.8 10.1 9.5 2.6 8.5 3.8 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RAP1 PF07218.11 EGD88666.2 - 8.5 4.5 6.9 13 4.0 6.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Spo7 PF03907.13 EGD88668.1 - 2e-89 298.9 0.0 2.8e-89 298.4 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein YL1 PF05764.13 EGD88668.1 - 4.8 7.2 8.1 9.6 6.2 8.1 1.4 1 1 0 1 1 1 0 YL1 nuclear protein Abhydrolase_1 PF00561.20 EGD88669.1 - 6.2e-21 75.2 0.0 5.1e-18 65.6 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD88669.1 - 9.5e-17 61.1 0.0 6.4e-16 58.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGD88669.1 - 1.3e-16 61.9 0.8 9.6e-16 59.0 0.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EGD88669.1 - 8.8e-05 22.3 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 EGD88669.1 - 0.00031 20.2 0.0 0.00056 19.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 EGD88669.1 - 0.0023 17.5 0.0 0.0052 16.4 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 EGD88669.1 - 0.0032 16.4 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EGD88669.1 - 0.0036 16.4 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Ser_hydrolase PF06821.13 EGD88669.1 - 0.011 15.6 0.0 0.089 12.7 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_3 PF07859.13 EGD88669.1 - 0.017 15.0 0.0 0.063 13.1 0.0 1.9 3 0 0 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGD88669.1 - 0.018 14.8 0.0 2.6 7.8 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 EGD88669.1 - 0.019 15.1 0.2 0.097 12.8 0.2 2.2 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 EGD88669.1 - 0.032 14.0 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EGD88669.1 - 0.05 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 EGD88669.1 - 0.063 12.7 0.0 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Herpes_pp85 PF04637.12 EGD88669.1 - 0.29 9.5 4.4 0.46 8.8 4.4 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) TatD_DNase PF01026.21 EGD88670.2 - 3.1e-39 134.9 0.0 4.8e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase TPP_enzyme_N PF02776.18 EGD88671.2 - 6.4e-33 113.8 0.2 2.6e-32 111.8 0.0 2.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGD88671.2 - 1.2e-19 70.6 0.0 2e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGD88671.2 - 6.2e-13 48.7 0.0 2.6e-12 46.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain NTP_transf_3 PF12804.7 EGD88671.2 - 0.072 13.4 0.6 1.7 9.0 0.6 2.7 1 1 0 1 1 1 0 MobA-like NTP transferase domain Chitin_synth_2 PF03142.15 EGD88672.2 - 5.3e-229 761.2 0.1 7.9e-229 760.6 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 EGD88672.2 - 4e-17 61.9 0.3 1.6e-16 60.0 0.4 2.0 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 EGD88672.2 - 1.3e-16 60.5 0.3 2.4e-10 40.4 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 EGD88672.2 - 4.2e-13 49.7 3.5 1.1e-12 48.3 3.5 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGD88672.2 - 2.3e-12 47.3 0.1 3.4e-11 43.5 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGD88672.2 - 0.00012 21.6 0.0 0.007 15.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGD88672.2 - 0.00076 19.3 0.0 0.37 10.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Myosin_head PF00063.21 EGD88672.2 - 0.15 10.2 0.2 8.8 4.4 0.0 2.1 1 1 0 2 2 2 0 Myosin head (motor domain) Chitin_synth_2 PF03142.15 EGD88673.1 - 1.7e-246 818.9 0.7 2.5e-246 818.4 0.7 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EGD88673.1 - 9.2e-73 245.6 0.0 6.5e-72 242.8 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 EGD88673.1 - 1.6e-19 69.8 0.3 4e-14 52.5 0.0 3.5 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 EGD88673.1 - 5e-15 55.2 0.4 1.3e-14 53.9 0.4 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EGD88673.1 - 3.9e-13 49.8 4.9 1e-12 48.4 4.9 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGD88673.1 - 1.2e-10 41.7 0.1 1e-09 38.7 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGD88673.1 - 0.00026 20.8 0.0 0.074 12.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGD88673.1 - 0.0023 17.4 0.2 0.029 13.8 0.2 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 RsgA_GTPase PF03193.16 EGD88673.1 - 0.018 15.0 0.0 0.33 10.9 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EGD88673.1 - 0.056 13.8 0.2 0.23 11.9 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain KH_1 PF00013.29 EGD88674.2 - 2.3e-27 94.6 1.9 1.9e-05 24.4 0.1 7.4 7 0 0 7 7 7 6 KH domain Ribosomal_S6 PF01250.17 EGD88674.2 - 0.038 14.3 0.0 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S6 RP-C_C PF11800.8 EGD88674.2 - 7.8 6.5 7.0 16 5.5 7.0 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Hydrolase PF00702.26 EGD88675.2 - 3.9e-08 33.8 0.0 4.9e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGD88675.2 - 5.6e-08 33.1 0.0 6.9e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGD88675.2 - 0.0064 16.5 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Dynactin PF12455.8 EGD88677.1 - 2.3e-102 342.1 1.5 2.3e-102 342.1 1.5 3.6 2 1 0 2 2 2 1 Dynein associated protein CAP_GLY PF01302.25 EGD88677.1 - 1.9e-20 72.6 0.1 3.2e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain APG6_N PF17675.1 EGD88677.1 - 0.044 14.3 0.2 0.044 14.3 0.2 8.3 4 2 4 8 8 8 0 Apg6 coiled-coil region HALZ PF02183.18 EGD88677.1 - 0.21 11.9 0.1 0.21 11.9 0.1 7.5 6 1 2 8 8 8 0 Homeobox associated leucine zipper Beta_elim_lyase PF01212.21 EGD88678.2 - 1.4e-67 228.0 0.1 1.5e-37 129.4 0.1 2.0 2 0 0 2 2 2 2 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EGD88678.2 - 0.0015 17.1 0.0 0.0027 16.3 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGD88678.2 - 0.0043 16.3 0.1 0.066 12.4 0.0 2.2 2 1 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGD88678.2 - 0.098 11.9 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Antimicrobial_2 PF08023.12 EGD88678.2 - 0.12 12.9 0.4 6.3 7.4 0.0 2.7 2 0 0 2 2 2 0 Frog antimicrobial peptide Solute_trans_a PF03619.16 EGD88680.1 - 1.4e-97 326.4 10.2 1.7e-97 326.1 10.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Podoplanin PF05808.11 EGD88680.1 - 1.3 9.1 2.7 2.3 8.3 2.7 1.4 1 0 0 1 1 1 0 Podoplanin GTP_EFTU PF00009.27 EGD88682.1 - 4.1e-67 225.5 0.2 5.6e-67 225.1 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGD88682.1 - 4.8e-30 103.8 0.0 3.3e-29 101.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EGD88682.1 - 3e-21 75.3 0.0 1e-20 73.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGD88682.1 - 3.2e-13 49.8 0.1 1.4e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGD88682.1 - 5.1e-12 45.7 0.0 1.5e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EGD88682.1 - 9.9e-05 22.4 0.1 0.00024 21.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PWI PF01480.17 EGD88683.1 - 6.9e-10 39.1 0.1 1.5e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EGD88683.1 - 7.8e-08 32.0 0.1 1.4e-05 24.8 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGD88683.1 - 3.9e-07 30.0 0.0 1.2e-05 25.2 0.1 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 EGD88683.1 - 0.00051 19.9 1.1 0.00087 19.1 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_occluded PF16842.5 EGD88683.1 - 0.0089 15.9 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif zf_CCCH_4 PF18345.1 EGD88683.1 - 0.013 15.5 1.4 0.024 14.7 1.4 1.4 1 0 0 1 1 1 0 Zinc finger domain CAF-1_p150 PF11600.8 EGD88683.1 - 0.2 11.3 16.3 0.35 10.5 16.3 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UPF0242 PF06785.11 EGD88683.1 - 0.21 11.7 5.5 0.35 10.9 5.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TipAS PF07739.13 EGD88683.1 - 2.3 8.8 9.0 12 6.4 0.1 2.6 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain RRM_3 PF08777.11 EGD88683.1 - 6.7 6.8 8.9 3.1 7.9 0.1 2.8 3 0 0 3 3 3 0 RNA binding motif adh_short_C2 PF13561.6 EGD88684.1 - 3e-55 187.3 0.0 3.8e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD88684.1 - 7.1e-46 156.1 0.0 9.1e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD88684.1 - 0.25 11.2 1.4 8.1 6.3 1.4 2.8 1 1 0 1 1 1 0 KR domain MFS_1 PF07690.16 EGD88685.2 - 3.2e-35 121.7 9.1 1e-30 106.9 3.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGD88685.2 - 7.1e-07 28.8 5.9 8.7e-07 28.5 2.2 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CLN3 PF02487.17 EGD88685.2 - 0.0026 16.9 1.2 0.0056 15.8 0.2 1.9 1 1 1 2 2 2 1 CLN3 protein DUF2776 PF10951.8 EGD88685.2 - 0.01 15.1 0.5 3.5 6.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2776) Wzy_C PF04932.15 EGD88685.2 - 0.021 14.4 0.5 0.24 11.0 0.2 2.4 2 0 0 2 2 2 0 O-Antigen ligase CitMHS PF03600.16 EGD88685.2 - 0.32 10.2 11.8 0.35 10.0 1.2 2.2 1 1 1 2 2 2 0 Citrate transporter DUF2207 PF09972.9 EGD88685.2 - 3.9 6.1 7.5 7.9 5.1 0.1 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Aminotran_1_2 PF00155.21 EGD88688.1 - 3.9e-38 131.6 0.0 5.3e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1989 PF09347.10 EGD88690.1 - 9.3e-65 217.3 0.0 1.1e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Abhydrolase_1 PF00561.20 EGD88691.1 - 1.4e-14 54.4 0.0 1.9e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD88691.1 - 1.4e-12 48.7 0.0 1.9e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGD88691.1 - 5.3e-08 32.4 0.0 1.2e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EGD88691.1 - 0.14 11.9 0.0 3.1 7.6 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF3425 PF11905.8 EGD88692.1 - 3.7e-10 39.8 3.0 1.1e-08 35.0 0.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EGD88692.1 - 0.094 12.8 7.8 0.18 11.9 7.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor BCDHK_Adom3 PF10436.9 EGD88695.1 - 9e-47 158.9 0.0 1.3e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGD88695.1 - 4.8e-09 36.7 0.0 2.2e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EGD88695.1 - 0.03 14.3 0.0 0.088 12.8 0.0 1.8 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain DUF2157 PF09925.9 EGD88696.1 - 0.026 14.3 0.4 0.026 14.3 0.4 2.9 1 1 2 3 3 3 0 Predicted membrane protein (DUF2157) HisKA_7TM PF16927.5 EGD88696.1 - 0.12 12.4 10.7 0.18 11.8 10.0 1.6 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase DUF2070 PF09843.9 EGD88696.1 - 7.5 4.7 14.8 0.048 12.0 5.6 1.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) Ketoacyl-synt_C PF02801.22 EGD88698.2 - 7.3e-35 119.5 0.3 1e-34 119.1 0.3 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EGD88698.2 - 3.6e-14 53.0 0.6 8.5e-13 48.5 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_C PF02803.18 EGD88698.2 - 0.0068 16.1 0.4 0.0068 16.1 0.4 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain Arginase PF00491.21 EGD88699.2 - 1e-86 291.0 0.1 1.2e-86 290.7 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EGD88699.2 - 0.0021 18.3 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 UPF0489 domain Ras PF00071.22 EGD88700.2 - 3.3e-52 176.3 0.0 4.2e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD88700.2 - 8.7e-19 67.9 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD88700.2 - 3.9e-06 26.4 0.0 5.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF1349 PF07081.11 EGD88702.1 - 1.8e-30 106.0 0.0 4.2e-30 104.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) MFS_1 PF07690.16 EGD88703.2 - 1.5e-15 57.0 41.5 1.6e-15 56.9 35.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGD88703.2 - 0.037 12.4 13.1 0.07 11.5 13.0 1.5 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) TMEM100 PF16311.5 EGD88703.2 - 0.88 9.2 3.7 4 7.0 0.7 2.5 2 0 0 2 2 2 0 Transmembrane protein 100 Folate_carrier PF01770.18 EGD88703.2 - 7 5.3 15.6 0.21 10.3 6.9 2.6 2 1 1 3 3 3 0 Reduced folate carrier p450 PF00067.22 EGD88704.2 - 1.1e-35 123.4 0.0 8.3e-23 80.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 NAPRTase PF04095.16 EGD88704.2 - 0.084 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Vint PF14623.6 EGD88705.2 - 6.6e-61 205.0 0.0 2.1e-60 203.3 0.0 1.8 2 0 0 2 2 2 1 Hint-domain Vwaint PF14624.6 EGD88705.2 - 2.6e-25 88.3 0.0 4.7e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like ABC_membrane PF00664.23 EGD88706.2 - 5.6e-88 295.2 15.0 2.5e-46 158.5 1.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGD88706.2 - 2e-33 115.8 0.0 4.4e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGD88706.2 - 4.6e-08 32.8 0.2 6.9e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGD88706.2 - 0.00085 19.0 0.1 0.00085 19.0 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGD88706.2 - 0.0038 17.1 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGD88706.2 - 0.017 15.4 0.0 0.066 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGD88706.2 - 0.021 14.7 0.2 0.07 13.0 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EGD88706.2 - 0.028 14.8 0.1 0.096 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 EGD88706.2 - 0.049 12.9 0.3 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 EGD88706.2 - 0.078 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EGD88706.2 - 0.15 12.5 0.1 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGD88706.2 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain CAP59_mtransfer PF11735.8 EGD88707.2 - 1.2e-72 244.5 0.0 1.5e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 TMEM214 PF10151.9 EGD88708.2 - 0.13 10.7 6.6 0.18 10.2 6.6 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator TERB2 PF15101.6 EGD88708.2 - 0.2 11.7 1.9 0.43 10.6 1.9 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Mitofilin PF09731.9 EGD88708.2 - 2.5 6.8 13.9 3.8 6.2 13.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GST_N PF02798.20 EGD88715.1 - 2.8e-15 56.4 0.0 9.3e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGD88715.1 - 1.5e-13 50.9 0.0 3.6e-13 49.7 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGD88715.1 - 1.6e-10 41.1 0.1 4.6e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGD88715.1 - 3.2e-10 40.1 0.0 7.3e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGD88715.1 - 1.7e-09 37.7 0.0 3.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGD88715.1 - 3.4e-06 27.0 0.0 8.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain APH PF01636.23 EGD88716.2 - 2e-05 24.7 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.6 EGD88717.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Iwr1 PF08574.10 EGD88718.2 - 9.4e-19 68.2 4.5 9.4e-19 68.2 4.5 3.2 3 1 1 4 4 4 1 Transcription factor Iwr1 RRM_1 PF00076.22 EGD88719.1 - 1.4e-40 136.9 0.0 5.3e-12 45.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGD88719.1 - 8.6e-15 54.4 0.0 0.0053 16.6 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif DUF4523 PF15023.6 EGD88719.1 - 2.9e-05 23.9 0.0 0.51 10.1 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM PF10378.9 EGD88719.1 - 7.8e-05 22.3 6.8 7.8e-05 22.3 6.8 3.0 3 1 0 3 3 3 1 Putative RRM domain RRM_7 PF16367.5 EGD88719.1 - 0.00014 22.0 0.0 0.26 11.4 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 EGD88719.1 - 0.00035 20.6 0.0 0.54 10.3 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif RRM_Rrp7 PF17799.1 EGD88719.1 - 0.031 14.1 0.0 1.2 8.9 0.0 3.0 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain YL1 PF05764.13 EGD88720.1 - 4e-63 213.8 32.3 7.8e-63 212.8 32.3 1.5 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 EGD88720.1 - 9.5e-14 50.9 0.4 1.6e-13 50.1 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain tRNA-synt_2 PF00152.20 EGD88722.1 - 5.6e-91 304.9 0.0 8.1e-91 304.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGD88722.1 - 7.3e-09 35.5 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF818 PF05677.12 EGD88723.1 - 0.053 12.5 2.1 0.084 11.8 2.1 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PUF PF00806.19 EGD88725.1 - 3.1e-29 99.0 0.0 1.2e-05 24.7 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EGD88725.1 - 5.7e-11 42.1 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioesterase PF00975.20 EGD88728.2 - 4.8e-18 66.1 0.0 7.4e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EGD88728.2 - 1.5e-06 29.0 0.0 2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGD88728.2 - 0.015 14.6 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGD88728.2 - 0.028 14.1 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EGD88728.2 - 0.044 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ribosomal_L9_C PF03948.14 EGD88728.2 - 0.15 12.5 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain DcpS PF05652.12 EGD88730.1 - 3.4e-34 117.8 0.0 5.8e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EGD88730.1 - 2.5e-31 108.5 0.4 3.7e-31 107.9 0.4 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Alk_phosphatase PF00245.20 EGD88731.1 - 1.2e-70 238.6 4.1 7.1e-70 236.0 4.1 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 EGD88731.1 - 1.1e-06 28.2 3.2 7.6e-06 25.5 3.1 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGD88731.1 - 9.1e-05 22.2 1.4 0.00014 21.5 1.4 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EGD88731.1 - 0.00072 18.3 0.2 0.0012 17.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) GPAT_N PF14829.6 EGD88731.1 - 0.023 14.7 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Metalloenzyme PF01676.18 EGD88731.1 - 0.032 13.6 0.2 0.089 12.1 0.2 1.7 1 0 0 1 1 1 0 Metalloenzyme superfamily RNase_H2_suC PF08615.11 EGD88732.1 - 6.1e-27 94.5 0.2 1e-26 93.8 0.0 1.4 2 0 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RNase_T PF00929.24 EGD88733.1 - 1.1e-19 71.5 0.0 3e-19 70.2 0.0 1.7 1 1 0 1 1 1 1 Exonuclease Nop53 PF07767.11 EGD88734.2 - 3.3e-81 273.7 40.0 4.8e-81 273.2 40.0 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Myb_Cef PF11831.8 EGD88735.1 - 1.9e-49 168.4 3.7 1.9e-49 168.4 3.7 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EGD88735.1 - 1.4e-21 76.4 5.8 2.1e-10 40.6 0.7 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGD88735.1 - 1.5e-19 70.0 4.7 1.5e-12 47.6 1.4 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EGD88735.1 - 0.059 13.5 0.1 1 9.5 0.0 2.7 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MOZ_SAS PF01853.18 EGD88736.2 - 8e-79 263.5 0.0 1.3e-78 262.8 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 EGD88736.2 - 3.2e-22 78.2 0.0 6.2e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 EGD88736.2 - 3.6e-22 77.7 0.3 7.2e-22 76.8 0.3 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EGD88736.2 - 0.005 17.2 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGD88736.2 - 0.045 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF1918 PF08940.11 EGD88736.2 - 0.08 12.6 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Orthopox_C10L PF07020.11 EGD88737.1 - 0.15 12.8 2.5 9 7.1 0.3 3.2 2 0 0 2 2 2 0 Orthopoxvirus C10L protein F1F0-ATPsyn_F PF10791.9 EGD88738.1 - 1.3e-38 131.4 0.1 1.4e-38 131.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 EGD88738.1 - 0.0079 16.5 0.0 0.0095 16.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.12 EGD88739.1 - 2.1e-36 124.1 2.3 3e-36 123.5 2.3 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Nipped-B_C PF12830.7 EGD88740.1 - 2.4e-47 161.4 8.9 5.5e-46 156.9 1.8 3.9 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EGD88740.1 - 1.2e-10 41.4 2.5 1.2e-10 41.4 2.5 2.9 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 EGD88740.1 - 0.00012 21.4 0.9 0.2 10.8 0.0 2.9 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 EGD88740.1 - 0.00025 21.1 4.7 0.25 11.4 0.0 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGD88740.1 - 0.0018 18.4 4.0 0.82 10.1 0.3 4.9 4 0 0 4 4 4 1 HEAT repeat FAM176 PF14851.6 EGD88740.1 - 0.1 12.3 0.7 0.41 10.3 0.5 2.1 2 0 0 2 2 2 0 FAM176 family Adaptin_N PF01602.20 EGD88740.1 - 0.15 10.6 11.4 0.073 11.6 2.9 3.5 2 1 1 3 3 3 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 EGD88740.1 - 0.15 12.7 0.6 2 9.0 0.2 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF3391 PF11871.8 EGD88740.1 - 0.5 10.9 4.8 7.1 7.2 1.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) TFIIS_C PF01096.18 EGD88742.2 - 2.6e-15 56.0 1.7 2.6e-15 56.0 1.7 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGD88742.2 - 2.6e-06 27.2 0.5 2.6e-06 27.2 0.5 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit RecR PF02132.15 EGD88742.2 - 0.0026 17.3 0.9 0.0026 17.3 0.9 2.0 2 0 0 2 2 2 1 RecR protein tRNA-synt_1f PF01921.18 EGD88742.2 - 0.011 14.7 0.3 0.017 14.1 0.3 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Ribosomal_S27e PF01667.17 EGD88742.2 - 0.013 15.2 3.9 2.8 7.7 0.0 3.4 2 1 1 3 3 3 0 Ribosomal protein S27 zinc_ribbon_2 PF13240.6 EGD88742.2 - 0.017 14.9 10.1 10 6.0 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EGD88742.2 - 0.025 14.0 8.0 4.7 6.8 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Prok-RING_1 PF14446.6 EGD88742.2 - 0.038 13.9 3.8 5.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 NMD3 PF04981.13 EGD88742.2 - 0.058 12.9 4.6 0.14 11.6 0.4 2.1 1 1 0 2 2 2 0 NMD3 family DZR PF12773.7 EGD88742.2 - 0.063 13.3 8.7 0.15 12.1 0.5 2.7 1 1 2 3 3 3 0 Double zinc ribbon zf-RING_7 PF02591.15 EGD88742.2 - 0.094 12.9 8.1 1.3 9.3 0.1 3.5 3 1 1 4 4 4 0 C4-type zinc ribbon domain DpnI PF06044.12 EGD88742.2 - 0.35 10.5 2.8 0.38 10.4 0.2 2.0 1 1 0 2 2 2 0 Dam-replacing family Zn-ribbon_8 PF09723.10 EGD88742.2 - 0.53 10.5 9.8 0.91 9.7 0.1 3.1 3 0 0 3 3 3 0 Zinc ribbon domain Lar_restr_allev PF14354.6 EGD88742.2 - 0.53 10.7 5.3 3.1 8.2 2.0 2.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn_ribbon_recom PF13408.6 EGD88742.2 - 0.62 10.6 8.2 3.1 8.4 0.3 2.6 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain ArfGap PF01412.18 EGD88742.2 - 0.67 10.1 4.5 7.6 6.7 0.2 2.2 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf CpXC PF14353.6 EGD88742.2 - 0.87 9.6 7.0 1.2 9.2 1.3 2.7 1 1 1 2 2 2 0 CpXC protein zf-C4_Topoisom PF01396.19 EGD88742.2 - 0.96 9.3 5.1 1.2 9.0 0.4 3.0 2 2 1 3 3 3 0 Topoisomerase DNA binding C4 zinc finger OrfB_Zn_ribbon PF07282.11 EGD88742.2 - 1.1 9.3 9.2 7 6.7 2.4 2.7 2 2 0 2 2 2 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 EGD88742.2 - 1.8 8.8 6.2 5.3 7.3 0.1 3.2 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.12 EGD88742.2 - 3.7 7.2 13.6 5.9 6.5 0.3 3.4 2 2 1 3 3 3 0 TFIIB zinc-binding zf-IS66 PF13005.7 EGD88742.2 - 8.9 6.8 11.3 4.1 7.9 0.1 3.6 3 1 1 4 4 4 0 zinc-finger binding domain of transposase IS66 HEAT_2 PF13646.6 EGD88743.1 - 7.4e-29 100.0 5.8 2.4e-12 47.1 0.2 3.6 2 2 1 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 EGD88743.1 - 1.1e-20 72.2 0.5 0.0032 18.0 0.0 6.6 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EGD88743.1 - 5.2e-06 26.3 3.7 3.1 8.3 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 EGD88743.1 - 0.00012 22.5 7.4 0.24 11.9 0.0 6.0 5 2 2 7 7 7 1 HEAT-like repeat PUB_1 PF18486.1 EGD88743.1 - 0.12 12.2 0.4 0.74 9.7 0.1 2.5 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain Paramyxo_P_V_N PF13825.6 EGD88743.1 - 0.72 9.2 2.3 0.89 8.9 0.1 2.1 3 0 0 3 3 3 0 Paramyxovirus structural protein V/P N-terminus Pyr_redox_2 PF07992.14 EGD88744.2 - 1.6e-40 139.2 0.0 2.2e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGD88744.2 - 2.3e-10 40.9 0.0 4.8e-09 36.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EGD88744.2 - 1.2e-05 24.5 0.1 4.6e-05 22.7 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGD88744.2 - 0.00018 21.2 0.3 0.0006 19.5 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EGD88744.2 - 0.0003 20.1 0.1 0.00074 18.9 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGD88744.2 - 0.0032 17.9 0.1 0.0092 16.4 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 EGD88744.2 - 0.24 11.4 0.9 3.4 7.7 0.0 2.9 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand CLTH PF10607.9 EGD88745.1 - 2.6e-33 115.0 0.3 3.5e-33 114.6 0.3 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGD88745.1 - 2.1e-09 37.0 0.0 4.7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 LisH PRK PF00485.18 EGD88746.1 - 5e-56 189.6 0.0 6.3e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGD88746.1 - 5.2e-06 27.0 0.0 8.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGD88746.1 - 0.00017 21.0 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.17 EGD88746.1 - 0.0062 16.7 0.1 0.024 14.8 0.1 1.8 1 1 1 2 2 2 1 Helicase HerA, central domain CPT PF07931.12 EGD88746.1 - 0.0081 16.0 0.0 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 EGD88746.1 - 0.012 15.3 0.1 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase AAA_17 PF13207.6 EGD88746.1 - 0.034 14.6 0.5 0.83 10.1 0.5 2.4 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 EGD88746.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EGD88746.1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGD88746.1 - 0.16 12.5 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter NUC153 PF08159.12 EGD88747.1 - 2.6e-14 52.7 8.3 1.4e-13 50.4 0.2 3.6 3 0 0 3 3 3 2 NUC153 domain ATP-synt_J PF04911.12 EGD88747.1 - 0.057 13.0 0.5 0.42 10.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase j chain DUF4148 PF13663.6 EGD88747.1 - 0.2 11.9 0.1 0.2 11.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Npa1 PF11707.8 EGD88748.1 - 1e-92 311.1 1.1 2.8e-92 309.7 1.1 1.8 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EGD88748.1 - 1e-55 188.5 0.0 6.5e-55 185.8 0.0 2.4 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 RhoGAP PF00620.27 EGD88748.1 - 0.095 12.5 0.0 9.6 6.0 0.0 3.0 2 0 0 2 2 2 0 RhoGAP domain Mating_N PF12731.7 EGD88748.1 - 0.12 12.5 0.7 0.42 10.7 0.0 2.3 2 0 0 2 2 2 0 Mating-type protein beta 1 HA2 PF04408.23 EGD88750.1 - 1.5e-23 83.1 1.0 4.3e-23 81.7 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGD88750.1 - 2.7e-18 66.1 0.0 5.9e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGD88750.1 - 2.2e-13 50.5 0.0 5.9e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EGD88750.1 - 9.6e-10 38.7 1.4 2.7e-09 37.2 1.4 1.8 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 EGD88750.1 - 0.00018 21.3 0.1 0.00044 20.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 EGD88750.1 - 0.0013 17.9 0.0 0.003 16.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGD88750.1 - 0.032 14.5 0.2 0.1 12.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGD88750.1 - 0.071 13.5 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Helicase_C PF00271.31 EGD88751.2 - 2.2e-06 28.0 0.0 4.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sec1 PF00995.23 EGD88752.2 - 9.6e-101 338.8 0.0 1.3e-100 338.4 0.0 1.1 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.23 EGD88753.1 - 4.7e-08 32.8 0.2 1.2e-07 31.5 0.2 1.6 1 0 0 1 1 1 1 G-patch domain adh_short PF00106.25 EGD88754.1 - 2.6e-13 49.9 0.0 2.7e-10 40.0 0.0 2.7 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.10 EGD88754.1 - 6.7e-05 22.9 0.0 0.00018 21.5 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 EGD88754.1 - 7.3e-05 22.4 0.0 0.00027 20.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EGD88754.1 - 0.00038 20.0 0.0 0.0011 18.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RDD PF06271.12 EGD88754.1 - 0.067 13.4 2.2 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 RDD family Epimerase PF01370.21 EGD88755.1 - 5.6e-48 163.5 0.0 7.4e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGD88755.1 - 5.7e-48 164.0 0.0 1.3e-47 162.8 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGD88755.1 - 4.1e-15 55.5 0.0 6.4e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGD88755.1 - 1.8e-12 47.0 0.0 2.4e-11 43.3 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGD88755.1 - 1.6e-11 43.9 0.0 2.2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EGD88755.1 - 5.4e-11 42.3 0.0 9.4e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD88755.1 - 2.6e-07 30.7 0.0 4.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EGD88755.1 - 1.4e-05 24.8 0.0 4.8e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 EGD88755.1 - 0.00012 21.4 0.0 0.014 14.6 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EGD88755.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGD88755.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 EGD88755.1 - 0.012 15.2 0.1 0.026 14.1 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EGD88755.1 - 0.029 14.2 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EGD88756.1 - 3.5e-26 92.2 0.0 4.1e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGD88756.1 - 1.3e-09 38.0 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EGD88756.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGD88756.1 - 3e-05 23.2 0.0 3.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EGD88756.1 - 0.00047 20.4 0.0 0.0008 19.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FIST_C PF10442.9 EGD88756.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 FIST C domain PAT1 PF09770.9 EGD88757.2 - 4e-296 984.9 16.2 4.6e-296 984.7 16.2 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.16 EGD88758.1 - 1.4e-127 425.5 11.2 1.7e-127 425.2 11.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SIC PF03482.13 EGD88758.1 - 0.005 17.0 0.7 0.012 15.8 0.7 1.7 1 0 0 1 1 1 1 sic protein repeat FAP PF07174.11 EGD88758.1 - 0.11 12.0 9.2 0.16 11.4 9.2 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Ribosom_S12_S23 PF00164.25 EGD88759.1 - 2.1e-30 104.7 1.8 2.8e-30 104.3 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 HTH_Tnp_IS1 PF12759.7 EGD88759.1 - 0.031 13.9 0.1 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 InsA C-terminal domain UMP1 PF05348.11 EGD88760.1 - 1.2e-38 132.0 0.1 1.5e-38 131.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.6 EGD88761.1 - 1.7e-12 47.4 0.0 3.8e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGD88761.1 - 0.0052 17.3 0.1 0.016 15.8 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EGD88761.1 - 0.0086 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family IML1 PF12257.8 EGD88762.1 - 2.6e-107 358.2 0.0 3.7e-107 357.7 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EGD88762.1 - 3.8e-29 100.5 1.0 7.6e-29 99.6 1.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FNIP_N PF14636.6 EGD88763.1 - 5.2e-32 112.0 0.6 5.2e-32 112.0 0.6 4.4 3 2 0 5 5 5 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.6 EGD88763.1 - 0.047 13.7 0.2 0.14 12.1 0.1 1.8 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain C9orf72-like PF15019.6 EGD88763.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 C9orf72-like protein family zf-C3HC4_3 PF13920.6 EGD88764.2 - 0.0015 18.3 11.1 0.0029 17.4 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGD88764.2 - 0.19 11.7 8.3 0.33 10.8 8.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGD88764.2 - 0.38 10.7 11.2 1 9.4 11.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EGD88764.2 - 0.67 9.9 14.6 0.69 9.8 13.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 EGD88765.1 - 4.7e-09 35.7 24.0 0.00016 21.5 0.0 6.8 7 1 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGD88765.1 - 1.6e-08 34.9 15.9 0.0074 16.8 1.6 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGD88765.1 - 1.6e-07 31.0 0.3 0.13 12.6 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGD88765.1 - 4.2e-07 29.5 12.1 0.00029 20.5 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGD88765.1 - 2.7e-05 24.6 26.7 0.033 15.0 0.3 8.4 7 2 2 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGD88765.1 - 0.0001 22.9 25.5 0.00035 21.2 0.2 6.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGD88765.1 - 0.00038 20.1 10.1 0.01 15.5 0.1 5.6 6 0 0 6 6 6 1 TPR repeat TPR_12 PF13424.6 EGD88765.1 - 0.00054 20.2 17.1 0.21 11.9 2.4 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGD88765.1 - 0.00085 19.8 14.0 3.4 8.5 0.2 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGD88765.1 - 0.004 17.1 8.5 0.83 9.8 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGD88765.1 - 0.16 12.4 6.6 37 5.0 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGD88765.1 - 0.45 10.5 11.9 5 7.1 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Pmp3 PF01679.17 EGD88766.1 - 2.2e-19 69.4 10.1 3e-19 69.0 10.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SH3_9 PF14604.6 EGD88767.2 - 1.7e-05 24.6 1.7 1.8e-05 24.5 0.2 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EGD88767.2 - 0.00024 20.6 0.1 0.00044 19.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 EGD88767.2 - 0.014 14.9 0.0 0.029 13.8 0.0 1.5 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Syndecan PF01034.20 EGD88767.2 - 0.026 14.4 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 EGD88767.2 - 0.22 10.9 1.2 0.44 10.0 1.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Fungal_trans PF04082.18 EGD88773.1 - 3.7e-20 72.1 0.1 9.7e-20 70.7 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD88773.1 - 8.7e-05 22.6 7.8 0.00019 21.5 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BDV_P10 PF06515.11 EGD88773.1 - 0.17 11.9 2.3 0.91 9.6 2.3 2.3 1 0 0 1 1 1 0 Borna disease virus P10 protein Na_Ca_ex PF01699.24 EGD88775.1 - 1e-36 126.2 34.1 5.9e-20 71.8 16.3 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3951 PF13131.6 EGD88775.1 - 0.12 12.5 0.9 1.1 9.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) GHMP_kinases_C PF08544.13 EGD88776.2 - 4.5e-08 33.4 0.0 6.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 GHMP kinases C terminal MCM PF00493.23 EGD88777.1 - 2.4e-99 331.0 0.1 3.6e-99 330.4 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGD88777.1 - 3.6e-38 130.3 0.4 7.5e-38 129.2 0.4 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EGD88777.1 - 1.5e-32 112.1 2.2 1.5e-32 112.1 2.2 2.1 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EGD88777.1 - 3.2e-24 85.2 0.5 9.5e-24 83.6 0.5 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGD88777.1 - 1.8e-20 73.5 1.5 4.6e-20 72.1 0.4 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGD88777.1 - 7.2e-05 22.3 0.0 0.00037 19.9 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGD88777.1 - 0.0038 17.2 0.0 0.013 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGD88777.1 - 0.0059 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGD88777.1 - 0.018 14.8 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain GIDA_assoc PF13932.6 EGD88777.1 - 0.064 13.4 2.6 0.14 12.3 2.6 1.6 1 0 0 1 1 1 0 GidA associated domain EamA PF00892.20 EGD88778.1 - 2.9e-06 27.5 14.0 2.5e-05 24.5 14.0 1.9 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EGD88778.1 - 0.02 14.9 4.3 0.028 14.4 4.3 1.2 1 0 0 1 1 1 0 Putative transmembrane family 234 Voltage_CLC PF00654.20 EGD88779.2 - 9.7e-33 113.9 7.8 1.3e-32 113.4 7.8 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EGD88779.2 - 2.1e-09 37.7 0.0 0.00038 20.8 0.1 2.6 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.23 EGD88780.1 - 7.4e-14 51.8 0.7 1.3e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GNVR PF13807.6 EGD88780.1 - 0.32 10.9 1.4 2.3 8.2 0.0 2.7 2 2 2 4 4 4 0 G-rich domain on putative tyrosine kinase UCR_TM PF02921.14 EGD88781.1 - 7.3e-11 42.4 0.5 2.4e-10 40.7 0.5 1.9 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 EGD88781.1 - 3.2e-10 39.8 0.0 5.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain She9_MDM33 PF05546.11 EGD88782.2 - 1.2e-87 292.8 9.3 1.7e-87 292.4 9.3 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family MBD_C PF14048.6 EGD88782.2 - 0.0045 17.7 0.1 0.019 15.6 0.1 2.2 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 PsbH PF00737.20 EGD88782.2 - 0.048 13.4 0.8 0.097 12.4 0.8 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein DUF4407 PF14362.6 EGD88782.2 - 0.22 10.8 4.6 0.11 11.8 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SKA1 PF07160.12 EGD88782.2 - 0.71 9.7 9.6 0.037 13.9 2.2 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Aminotran_1_2 PF00155.21 EGD88783.2 - 9.3e-35 120.5 0.0 1.1e-34 120.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGD88783.2 - 0.009 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.21 EGD88783.2 - 0.12 11.0 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III Zn_clus PF00172.18 EGD88784.2 - 1.4e-16 60.3 31.4 3.7e-08 33.4 10.3 2.7 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGD88784.2 - 3.2e-09 36.2 1.3 3.2e-09 36.2 1.3 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain PNP_phzG_C PF10590.9 EGD88785.2 - 1.5e-22 79.4 1.5 1.8e-22 79.1 1.5 1.1 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region PPR_2 PF13041.6 EGD88786.1 - 6.7e-42 141.5 11.6 1e-08 35.2 0.0 13.2 11 3 3 14 14 14 7 PPR repeat family PPR_3 PF13812.6 EGD88786.1 - 2.5e-32 110.7 1.5 0.00013 21.9 0.0 10.4 8 4 3 11 11 11 7 Pentatricopeptide repeat domain PPR PF01535.20 EGD88786.1 - 2.9e-23 80.4 16.2 0.0011 19.1 0.0 13.3 14 0 0 14 14 14 4 PPR repeat PPR_long PF17177.4 EGD88786.1 - 9.7e-19 67.6 12.6 1.3e-08 34.5 0.1 5.8 5 1 0 6 6 6 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EGD88786.1 - 3.1e-17 62.0 0.9 9.3e-06 25.2 0.1 9.2 11 0 0 11 11 11 3 PPR repeat RPM2 PF08579.11 EGD88786.1 - 4e-08 33.7 0.1 5.2e-06 26.9 0.0 3.6 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.11 EGD88786.1 - 0.027 13.6 0.9 2.2 7.3 0.0 3.6 4 0 0 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway F-box_4 PF15966.5 EGD88788.1 - 0.00067 19.5 1.7 0.00088 19.1 0.1 2.0 2 1 0 2 2 2 1 F-box F-box PF00646.33 EGD88788.1 - 0.00068 19.4 0.1 0.0016 18.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGD88788.1 - 0.00094 19.0 0.8 0.0025 17.7 0.8 1.7 1 0 0 1 1 1 1 F-box-like Ribosomal_L7Ae PF01248.26 EGD88790.2 - 2.6e-25 88.0 0.0 3.4e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EGD88790.2 - 0.00078 19.5 0.1 0.001 19.1 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EGD88790.2 - 0.0027 17.5 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 PELOTA RNA binding domain EHN PF06441.12 EGD88794.1 - 1.4e-29 102.6 2.0 5.2e-28 97.6 0.2 2.7 3 0 0 3 3 3 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EGD88794.1 - 2.9e-12 46.8 0.0 1e-11 45.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD88794.1 - 1.2e-06 29.3 0.1 2.1e-06 28.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L17 PF01196.19 EGD88795.1 - 0.026 15.4 0.5 0.52 11.2 0.0 2.8 2 1 0 2 2 2 0 Ribosomal protein L17 tRNA_NucTran2_2 PF13735.6 EGD88795.1 - 0.031 14.3 0.9 0.052 13.5 0.9 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Pyridox_oxase_2 PF12766.7 EGD88797.1 - 3.4e-24 85.4 0.0 5.8e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase LRR_9 PF14580.6 EGD88798.2 - 1.3e-50 171.3 0.1 2e-50 170.7 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EGD88798.2 - 8.6e-10 38.2 14.0 6.7e-06 25.8 3.5 3.0 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 EGD88798.2 - 2.5e-06 27.7 8.9 0.0001 22.6 1.4 3.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) T4_Gp59_C PF08994.10 EGD88798.2 - 0.017 15.8 0.0 0.028 15.0 0.0 1.3 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term HTH_38 PF13936.6 EGD88798.2 - 0.047 13.4 0.2 0.1 12.4 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0128 PF03673.13 EGD88798.2 - 0.087 12.3 0.2 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) DUF4349 PF14257.6 EGD88798.2 - 0.13 11.7 1.3 0.22 10.9 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) GDA1_CD39 PF01150.17 EGD88799.1 - 2e-109 366.1 0.0 2.8e-109 365.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Acyltransferase PF01553.21 EGD88800.2 - 1.8e-17 63.2 0.0 3.3e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DHHC PF01529.20 EGD88800.2 - 0.0089 16.1 0.1 0.024 14.7 0.0 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase WD40 PF00400.32 EGD88803.2 - 6.5e-08 33.1 2.5 0.07 14.0 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Rad52_Rad22 PF04098.15 EGD88803.2 - 0.028 14.3 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein ParD_like PF11903.8 EGD88803.2 - 0.029 14.4 0.2 0.066 13.3 0.2 1.5 1 0 0 1 1 1 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system ANAPC4_WD40 PF12894.7 EGD88803.2 - 0.061 13.6 0.1 0.94 9.8 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans_2 PF11951.8 EGD88804.1 - 9.2e-10 37.9 4.8 2.7e-08 33.1 0.3 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD88804.1 - 2.6e-05 24.3 10.6 6.5e-05 23.0 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EGD88805.1 - 1.1e-43 149.5 57.1 5.4e-43 147.3 55.7 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD88805.1 - 9.4e-11 41.2 35.1 6.8e-08 31.8 18.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EGD88805.1 - 8.9e-07 27.7 23.5 1.2e-06 27.3 23.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GATase PF00117.28 EGD88806.1 - 1.7e-14 54.0 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EGD88806.1 - 0.024 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EGD88806.1 - 0.069 12.9 0.3 0.33 10.7 0.3 2.2 1 1 0 1 1 1 0 Peptidase C26 DUF775 PF05603.12 EGD88807.2 - 1.3e-66 223.9 0.0 1.5e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.28 EGD88808.2 - 5.7e-12 45.8 0.0 8.1e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.15 EGD88809.1 - 1.5e-46 158.0 0.0 1.7e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.11 EGD88810.1 - 1.7e-118 396.0 0.0 2e-118 395.8 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 EGD88812.1 - 9.7e-15 54.4 0.0 2e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain NMU PF02070.15 EGD88812.1 - 0.17 11.8 1.5 4 7.4 0.1 2.5 2 0 0 2 2 2 0 Neuromedin U UPF0086 PF01868.16 EGD88813.1 - 1.8e-31 107.9 0.1 3.2e-31 107.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Copper-bind PF00127.20 EGD88814.1 - 0.044 14.2 0.2 0.11 13.0 0.2 1.7 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Ank_2 PF12796.7 EGD88815.1 - 7e-72 238.1 14.1 4.5e-12 46.4 0.0 6.2 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGD88815.1 - 3e-39 132.5 7.1 1.3e-08 34.9 0.0 6.5 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGD88815.1 - 1.1e-37 127.9 10.4 1.9e-07 31.5 0.0 9.0 5 4 4 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD88815.1 - 6.5e-30 99.8 2.4 0.00018 21.7 0.0 10.6 11 0 0 11 11 11 6 Ankyrin repeat Ank PF00023.30 EGD88815.1 - 1.8e-29 100.9 3.6 0.022 15.2 0.0 10.9 11 0 0 11 11 11 8 Ankyrin repeat Trehalase_Ca-bi PF07492.11 EGD88815.1 - 0.0093 15.7 2.9 14 5.5 0.1 4.7 4 0 0 4 4 4 2 Neutral trehalase Ca2+ binding domain zf-C3HC4 PF00097.25 EGD88818.2 - 0.021 14.7 38.2 0.24 11.3 7.4 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 EGD88818.2 - 0.055 13.7 23.1 0.9 9.8 3.8 3.3 3 0 0 3 3 3 0 FYVE-type zinc finger zf-C3HC4_2 PF13923.6 EGD88818.2 - 0.99 9.3 41.0 0.63 9.9 6.7 3.7 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGD88818.2 - 1.3 8.7 29.9 0.039 13.6 4.2 3.3 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type Siva PF05458.12 EGD88818.2 - 8.8 6.0 22.6 0.9 9.2 2.8 3.3 3 0 0 3 3 3 0 Cd27 binding protein (Siva) DUF521 PF04412.13 EGD88819.1 - 0.063 12.0 0.0 0.071 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Cofilin_ADF PF00241.20 EGD88820.2 - 6.9e-18 64.6 0.0 8.8e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CinA_KH PF18146.1 EGD88821.2 - 0.036 14.2 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain MoCF_biosynth PF00994.24 EGD88821.2 - 0.15 11.7 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain Ras PF00071.22 EGD88822.1 - 7.5e-60 201.2 0.2 8.7e-60 201.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD88822.1 - 3.5e-20 72.4 0.0 5.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD88822.1 - 2.2e-07 30.5 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGD88822.1 - 3.2e-05 23.6 0.1 0.00031 20.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGD88822.1 - 4.9e-05 23.3 0.4 0.17 11.8 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGD88822.1 - 0.001 18.6 0.0 0.0016 17.9 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGD88822.1 - 0.0021 18.1 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EGD88822.1 - 0.0031 17.5 0.1 0.0059 16.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain DUF2075 PF09848.9 EGD88822.1 - 0.18 11.0 0.4 11 5.1 0.1 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 EGD88822.1 - 0.25 11.4 0.5 0.89 9.6 0.5 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 EGD88822.1 - 0.32 10.7 1.2 3.4 7.3 0.2 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein GATA PF00320.27 EGD88826.1 - 4.8e-27 93.3 17.4 2.3e-15 55.9 4.8 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 EGD88826.1 - 2.2e-07 30.3 3.4 0.0078 15.7 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 EGD88826.1 - 0.0011 19.1 2.1 1.1 9.4 0.2 2.7 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 EGD88826.1 - 0.0045 17.1 6.1 0.27 11.4 0.9 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 EGD88826.1 - 0.078 13.1 0.1 0.078 13.1 0.1 3.0 3 0 0 3 3 2 0 Zinc ribbon domain TDP43_N PF18694.1 EGD88826.1 - 0.17 11.7 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain Eapp_C PF10238.9 EGD88826.1 - 0.45 10.6 6.1 10 6.2 3.0 2.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein zf-RRN7 PF11781.8 EGD88826.1 - 0.46 10.2 7.9 2.3 8.0 0.3 2.9 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 EGD88826.1 - 1.8 8.7 16.1 0.9 9.6 1.0 3.5 2 2 1 3 3 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 EGD88826.1 - 3.6 7.5 4.7 23 4.9 0.7 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.11 EGD88826.1 - 4.6 7.2 13.4 0.85 9.6 0.3 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain COPI_assoc PF08507.10 EGD88827.1 - 4e-30 104.5 5.3 4.7e-30 104.3 5.3 1.0 1 0 0 1 1 1 1 COPI associated protein SPC12 PF06645.13 EGD88827.1 - 0.033 14.3 1.3 0.033 14.3 1.3 1.9 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DAO PF01266.24 EGD88828.2 - 1.1e-23 84.4 0.0 1.4e-23 84.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase OTU PF02338.19 EGD88830.2 - 4.8e-13 49.7 0.0 7.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Med3 PF11593.8 EGD88830.2 - 8.1 5.5 11.4 12 4.9 11.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Thioredoxin PF00085.20 EGD88831.1 - 7.4e-12 45.2 0.0 9.6e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EGD88831.1 - 0.0043 16.4 0.0 0.005 16.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 EGD88831.1 - 0.029 14.3 0.0 0.04 13.9 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 EGD88831.1 - 0.04 14.4 0.0 0.049 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DUF1681 PF07933.14 EGD88834.1 - 4.8e-51 172.4 0.0 6.7e-51 171.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) TMEM171 PF15471.6 EGD88834.1 - 2.3 7.2 5.6 3.4 6.5 5.6 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 IF-2B PF01008.17 EGD88835.1 - 1.5e-51 175.3 0.0 7e-51 173.1 0.0 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 EGD88835.1 - 0.0084 16.1 0.0 0.81 9.6 0.0 2.3 2 0 0 2 2 2 2 DeoR C terminal sensor domain Nuf2 PF03800.14 EGD88836.2 - 7.5e-41 139.5 0.1 2.2e-40 138.0 0.1 1.9 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 EGD88836.2 - 1.2e-30 106.0 17.0 1.2e-30 106.0 17.0 4.5 4 1 0 4 4 4 1 Designed helical repeat protein 10 domain Spc7 PF08317.11 EGD88836.2 - 1.2 8.0 54.2 1.8 7.4 22.6 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein FlaC_arch PF05377.11 EGD88836.2 - 1.6 9.2 22.6 0.66 10.4 1.1 5.1 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) VSG_B PF13206.6 EGD88836.2 - 2.7 7.2 0.0 2.7 7.2 0.0 3.9 2 1 2 4 4 4 0 Trypanosomal VSG domain Leu_zip PF15294.6 EGD88836.2 - 3.5 7.1 43.7 0.1 12.1 19.1 3.1 1 1 1 2 2 2 0 Leucine zipper Syntaxin-6_N PF09177.11 EGD88836.2 - 4.1 8.0 37.6 0.13 12.9 1.9 4.8 3 1 1 4 4 4 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 EGD88836.2 - 6.3 6.9 28.9 5.1 7.2 3.5 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Pox_Ag35 PF03286.14 EGD88837.1 - 0.0024 17.7 3.3 0.0032 17.3 3.3 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Eapp_C PF10238.9 EGD88837.1 - 0.0046 17.0 0.6 0.0053 16.8 0.6 1.2 1 0 0 1 1 1 1 E2F-associated phosphoprotein DUF2126 PF09899.9 EGD88837.1 - 0.0098 14.0 1.2 0.014 13.6 1.2 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme (DUF2126) RPA43_OB PF17875.1 EGD88837.1 - 0.039 14.6 0.6 0.06 14.0 0.6 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Tfb4 PF03850.14 EGD88837.1 - 0.04 13.4 0.9 0.058 12.9 0.9 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 Zip PF02535.22 EGD88837.1 - 0.054 12.7 0.4 0.059 12.6 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4820 PF16091.5 EGD88837.1 - 0.13 11.6 3.6 0.2 11.0 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) D123 PF07065.14 EGD88837.1 - 0.15 11.2 3.0 0.27 10.4 3.0 1.4 1 0 0 1 1 1 0 D123 CDC45 PF02724.14 EGD88837.1 - 0.16 10.3 5.3 0.19 10.0 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EGD88837.1 - 0.19 10.4 1.2 0.21 10.3 1.2 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EGD88837.1 - 0.26 11.0 1.1 0.34 10.6 1.1 1.2 1 0 0 1 1 1 0 Connexin RPN2_C PF18004.1 EGD88837.1 - 1.2 9.1 8.3 1.8 8.5 8.3 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TRAP_alpha PF03896.16 EGD88837.1 - 1.3 8.2 4.2 2 7.6 4.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cytomega_UL84 PF06284.11 EGD88837.1 - 6.1 5.2 5.3 7.8 4.8 5.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Adaptin_N PF01602.20 EGD88838.2 - 2.1e-96 323.6 0.0 2.4e-96 323.4 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGD88838.2 - 1.7e-16 60.7 0.0 5.9e-14 52.4 0.0 3.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGD88838.2 - 4e-10 40.0 1.2 0.00068 20.0 0.0 4.6 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 EGD88838.2 - 5.2e-07 29.4 0.5 0.14 12.5 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat SPO22 PF08631.10 EGD88838.2 - 0.00082 18.9 0.9 0.23 10.9 0.1 3.2 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like Cohesin_HEAT PF12765.7 EGD88838.2 - 0.0093 16.3 0.8 1.1 9.7 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion VHS PF00790.19 EGD88838.2 - 0.047 13.5 1.5 75 3.2 0.0 4.1 5 0 0 5 5 5 0 VHS domain Arm PF00514.23 EGD88838.2 - 0.35 11.0 1.8 6.2 7.0 0.2 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat YL1 PF05764.13 EGD88838.2 - 2.8 8.0 31.2 0.45 10.6 24.7 2.2 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 EGD88838.2 - 8.3 4.6 17.8 15 3.7 17.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Metallophos PF00149.28 EGD88840.2 - 1.3e-36 127.1 0.3 1.8e-36 126.6 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGD88840.2 - 0.067 13.6 0.3 0.19 12.2 0.3 1.8 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Rho_GDI PF02115.17 EGD88841.2 - 8.3e-37 126.8 0.0 1.1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor GFA PF04828.14 EGD88842.1 - 0.00018 21.8 1.7 0.00018 21.8 1.7 2.0 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 EGD88842.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 2.5 3 0 0 3 3 3 1 Nudix N-terminal zf-NADH-PPase PF09297.11 EGD88842.1 - 0.0035 17.0 0.1 0.0035 17.0 0.1 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain zf-CSL PF05207.13 EGD88842.1 - 0.15 11.8 1.6 0.2 11.4 0.5 1.8 2 0 0 2 2 2 0 CSL zinc finger KilA-N PF04383.13 EGD88843.2 - 0.035 14.0 0.9 2.3 8.1 0.0 3.0 2 1 1 3 3 3 0 KilA-N domain CLP1_N PF16573.5 EGD88844.2 - 2.6e-33 114.1 0.0 4.5e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 EGD88844.2 - 5.6e-24 85.0 0.0 1.1e-23 84.0 0.0 1.4 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 EGD88844.2 - 0.00035 20.4 0.0 0.0012 18.7 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EGD88844.2 - 0.0048 17.0 0.0 0.038 14.1 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EGD88844.2 - 0.027 14.2 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGD88844.2 - 0.038 14.5 0.1 0.19 12.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.10 EGD88844.2 - 0.14 11.6 0.0 0.33 10.4 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_35 PF14516.6 EGD88844.2 - 0.25 10.1 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain zf-piccolo PF05715.13 EGD88845.1 - 0.15 12.3 1.5 28 5.0 0.1 3.2 3 0 0 3 3 3 0 Piccolo Zn-finger ADH_zinc_N PF00107.26 EGD88846.2 - 2.6e-24 85.7 0.0 5.2e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGD88846.2 - 4.1e-18 66.7 0.0 8e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGD88846.2 - 1.1e-06 28.4 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EGD88846.2 - 0.029 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase MKLP1_Arf_bdg PF16540.5 EGD88846.2 - 0.073 13.1 0.1 18 5.5 0.0 2.3 2 0 0 2 2 2 0 Arf6-interacting domain of mitotic kinesin-like protein 1 Arb1 PF09692.10 EGD88847.1 - 5e-140 467.2 0.1 6.3e-140 466.9 0.1 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 APS_kinase PF01583.20 EGD88847.1 - 0.026 14.4 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PG_binding_1 PF01471.18 EGD88847.1 - 0.096 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain IPK PF03770.16 EGD88849.2 - 1.8e-60 204.2 0.0 2.2e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase DNA_pol_phi PF04931.13 EGD88849.2 - 0.23 9.5 3.0 0.31 9.1 3.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_S19 PF00203.21 EGD88850.1 - 5.6e-25 87.0 0.0 7.1e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.13 EGD88851.1 - 3.4e-22 78.1 0.1 6e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 EGD88851.1 - 6.2 7.5 6.5 31 5.2 6.5 2.2 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TRF PF08558.10 EGD88852.1 - 1.1e-81 274.0 1.8 1.6e-81 273.4 0.3 1.8 2 0 0 2 2 2 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EGD88852.1 - 0.0005 20.2 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain His_Phos_2 PF00328.22 EGD88853.1 - 1.8e-08 34.2 0.0 2.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.16 EGD88855.2 - 1.5e-05 24.1 19.1 0.025 13.5 19.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4006 PF13179.6 EGD88855.2 - 0.12 12.3 2.1 0.12 12.3 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF4267 PF14087.6 EGD88857.1 - 1.8e-26 92.4 5.2 2.2e-26 92.1 5.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Pkinase PF00069.25 EGD88858.1 - 1.3e-74 250.9 0.0 1.9e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD88858.1 - 1.4e-31 109.7 0.0 1.3e-22 80.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGD88858.1 - 1.2e-06 28.1 0.1 0.31 10.3 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 EGD88858.1 - 0.011 14.5 0.5 0.038 12.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EGD88858.1 - 0.03 13.7 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGD88858.1 - 0.072 13.0 0.0 3 7.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DASH_Dad3 PF08656.10 EGD88860.1 - 1.7e-29 101.7 2.1 2e-29 101.5 2.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 Peptidase_M75 PF09375.10 EGD88860.1 - 0.052 13.0 0.0 0.054 13.0 0.0 1.1 1 0 0 1 1 1 0 Imelysin SopE_GEF PF07487.13 EGD88860.1 - 0.19 11.8 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 SopE GEF domain Ribosomal_S5_C PF03719.15 EGD88861.1 - 1.5e-23 82.0 0.0 3.1e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EGD88861.1 - 6e-21 74.2 0.2 1.3e-20 73.1 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain tRNA_U5-meth_tr PF05958.11 EGD88865.2 - 2.8e-16 59.5 0.2 3.7e-15 55.8 0.0 2.4 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EGD88865.2 - 8.2e-05 22.4 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD88865.2 - 0.00013 22.6 0.0 0.00046 20.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 EGD88865.2 - 0.00029 20.5 0.0 0.00056 19.5 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 EGD88865.2 - 0.0033 18.0 0.0 0.025 15.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGD88865.2 - 0.034 13.5 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Actin PF00022.19 EGD88866.2 - 8.5e-88 294.7 0.0 8.6e-86 288.1 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGD88866.2 - 0.00014 20.8 0.1 0.0046 15.8 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EGD88866.2 - 0.0052 17.2 0.0 0.0076 16.6 0.0 1.4 1 0 0 1 1 1 1 Cell division protein FtsA Asparaginase_2 PF01112.18 EGD88867.2 - 1.8e-13 50.2 6.2 2.6e-13 49.7 6.2 1.2 1 0 0 1 1 1 1 Asparaginase SasG_E PF17041.5 EGD88867.2 - 0.0036 17.3 0.1 0.0081 16.1 0.1 1.6 1 0 0 1 1 1 1 E domain PEHE PF15275.6 EGD88867.2 - 0.048 14.3 1.3 0.12 13.0 1.3 1.8 1 1 0 1 1 1 0 PEHE domain Tfb4 PF03850.14 EGD88868.1 - 7.7e-110 366.7 0.0 1e-109 366.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 UNC45-central PF11701.8 EGD88869.1 - 5.3e-46 156.4 1.1 9.9e-45 152.2 1.0 2.8 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central Atx10homo_assoc PF09759.9 EGD88869.1 - 0.00081 19.4 0.0 1.4 9.0 0.0 2.8 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EGD88869.1 - 0.0035 17.3 12.4 17 5.6 0.1 7.6 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat Peptidase_S9 PF00326.21 EGD88869.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Trp_halogenase PF04820.14 EGD88870.1 - 6.8e-29 101.0 0.1 6.8e-14 51.6 0.0 2.5 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EGD88870.1 - 1.7e-08 34.1 0.0 4.2e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGD88870.1 - 3.7e-05 23.9 0.2 3.7e-05 23.9 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGD88870.1 - 0.00062 19.1 0.1 0.0011 18.3 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGD88870.1 - 0.00068 19.1 1.2 0.0014 18.0 0.2 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EGD88870.1 - 0.0014 17.8 0.1 0.0029 16.8 0.1 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGD88870.1 - 0.0031 16.3 0.1 0.006 15.3 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein TrkA_N PF02254.18 EGD88870.1 - 0.011 15.9 0.1 4.1 7.7 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.24 EGD88870.1 - 0.013 14.6 0.9 0.03 13.4 0.2 1.9 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 EGD88870.1 - 0.02 14.5 0.5 0.044 13.4 0.4 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase p450 PF00067.22 EGD88871.1 - 1.8e-27 96.2 0.0 2.5e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGD88872.2 - 1.5e-06 27.2 0.0 1.6e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 EGD88873.2 - 2.5e-07 30.7 6.0 6.2e-07 29.4 6.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EGD88875.1 - 6.2e-42 143.8 48.6 6.2e-42 143.8 48.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGD88875.1 - 1.6e-18 66.5 15.5 3.1e-18 65.5 15.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGD88875.1 - 6.6e-12 45.0 10.5 6.6e-12 45.0 10.5 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter DUF1422 PF07226.11 EGD88875.1 - 0.016 15.2 0.2 0.016 15.2 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1422) PsbY PF06298.11 EGD88875.1 - 0.12 12.3 0.4 0.12 12.3 0.4 1.9 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) ABC_tran PF00005.27 EGD88876.1 - 5e-32 111.3 0.0 9.6e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGD88876.1 - 1e-24 87.7 16.5 1e-24 87.7 16.5 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 EGD88876.1 - 2.6e-07 30.3 0.0 0.00043 19.8 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGD88876.1 - 0.00085 19.0 0.1 0.0021 17.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGD88876.1 - 0.0011 19.2 0.0 0.0046 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGD88876.1 - 0.0026 18.1 0.2 0.015 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 EGD88876.1 - 0.011 16.0 0.2 0.26 11.6 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EGD88876.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGD88876.1 - 0.013 16.0 0.0 0.027 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 EGD88876.1 - 0.028 13.4 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain RsgA_GTPase PF03193.16 EGD88876.1 - 0.029 14.3 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 EGD88876.1 - 0.05 13.3 0.1 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EGD88876.1 - 0.06 13.0 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EGD88876.1 - 0.069 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EGD88876.1 - 0.074 13.1 0.3 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 EGD88876.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Aminotran_1_2 PF00155.21 EGD88877.2 - 5.8e-15 55.3 0.0 7e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGD88877.2 - 0.18 11.0 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase p450 PF00067.22 EGD88879.1 - 1.6e-34 119.5 0.0 2.3e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.14 EGD88880.1 - 1.9e-17 63.5 0.0 3e-16 59.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGD88880.1 - 0.00039 20.4 0.4 1.2 9.1 0.3 3.3 2 2 1 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 EGD88880.1 - 0.00041 20.0 1.2 0.0068 16.0 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGD88880.1 - 0.0011 18.1 0.1 0.0023 17.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGD88880.1 - 0.0015 18.7 0.5 0.003 17.7 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGD88880.1 - 0.0071 15.6 0.4 2.1 7.5 0.2 3.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGD88880.1 - 0.031 13.0 0.1 0.17 10.6 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EGD88880.1 - 0.042 13.1 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EGD88880.1 - 0.054 12.6 0.4 0.12 11.5 0.5 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A DCP2 PF05026.13 EGD88881.1 - 0.072 13.4 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 Dcp2, box A domain UvrB_inter PF17757.1 EGD88881.1 - 0.077 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 UvrB interaction domain Pyr_redox_2 PF07992.14 EGD88882.1 - 1.1e-10 41.3 0.0 2.2e-10 40.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGD88882.1 - 0.00023 20.5 0.1 0.0016 17.8 0.0 2.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGD88882.1 - 0.00058 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EGD88882.1 - 0.002 17.3 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGD88882.1 - 0.0025 18.0 0.1 0.0052 17.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGD88882.1 - 0.0082 14.9 0.2 0.048 12.4 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EGD88882.1 - 0.018 14.4 0.9 0.028 13.8 0.9 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EGD88882.1 - 0.1 11.7 0.1 0.29 10.2 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EGD88882.1 - 0.12 12.9 0.0 0.39 11.2 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 EGD88882.1 - 0.14 11.4 0.2 0.24 10.6 0.2 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EGD88882.1 - 0.2 11.6 4.2 1.3 9.0 0.8 2.5 1 1 1 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 EGD88882.1 - 0.44 10.1 2.6 0.59 9.6 1.3 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGD88883.1 - 3.2e-16 59.4 0.0 5.1e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGD88883.1 - 1.4e-05 24.1 0.0 5e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 EGD88883.1 - 9.2e-05 21.7 0.0 0.00014 21.1 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGD88883.1 - 0.00024 21.3 0.7 0.0006 20.0 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGD88883.1 - 0.00051 20.1 0.0 2.4 8.1 0.1 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.14 EGD88883.1 - 0.0012 17.7 0.0 0.0024 16.6 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EGD88883.1 - 0.0015 18.2 0.3 0.0045 16.6 0.0 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGD88883.1 - 0.0028 16.8 0.0 0.0057 15.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EGD88883.1 - 0.003 16.9 0.0 0.0059 15.9 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGD88883.1 - 0.0088 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EGD88883.1 - 0.013 14.6 0.0 0.21 10.6 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 EGD88883.1 - 0.037 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EGD88883.1 - 0.039 13.2 0.5 0.075 12.3 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EGD88883.1 - 0.064 12.6 1.2 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Methyltransf_2 PF00891.18 EGD88884.1 - 1e-30 106.6 0.0 3e-30 105.1 0.0 1.8 1 1 1 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGD88884.1 - 3.2e-05 23.8 0.0 6.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 EGD88884.1 - 0.00017 21.6 0.2 0.00052 20.0 0.2 1.9 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.12 EGD88884.1 - 0.037 14.8 0.0 0.12 13.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Rrf2 PF02082.20 EGD88884.1 - 0.054 13.9 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator Methyltransf_25 PF13649.6 EGD88884.1 - 0.1 13.3 0.0 0.47 11.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain GST_C PF00043.25 EGD88885.1 - 2.4e-07 30.9 0.0 4.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGD88885.1 - 2e-06 27.9 0.0 3.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGD88885.1 - 4e-05 23.8 0.0 8.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGD88885.1 - 4.8e-05 23.7 0.0 8.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGD88885.1 - 0.00016 21.6 0.1 0.0003 20.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGD88885.1 - 0.0047 17.2 0.0 0.0091 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 EGD88885.1 - 0.068 13.5 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein p450 PF00067.22 EGD88886.1 - 1.1e-49 169.4 0.0 1.5e-49 169.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M19 PF01244.21 EGD88887.2 - 1.6e-100 336.4 0.0 1.9e-100 336.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) HAS-barrel PF09378.10 EGD88887.2 - 0.014 15.5 0.0 3.1 8.0 0.1 2.4 2 0 0 2 2 2 0 HAS barrel domain Stig1 PF04885.13 EGD88888.2 - 2.1e-27 96.3 210.6 9e-05 23.0 17.0 10.5 2 2 8 10 10 10 9 Stigma-specific protein, Stig1 AMP-binding PF00501.28 EGD88889.1 - 2e-76 257.3 0.0 3e-76 256.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGD88889.1 - 4.7e-52 177.2 0.0 5.3e-28 97.9 0.0 2.5 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EGD88889.1 - 1.3e-18 67.1 0.3 2e-08 34.4 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGD88889.1 - 0.00013 22.9 0.1 0.00031 21.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 EGD88889.1 - 0.12 12.1 0.4 0.83 9.4 0.0 2.3 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain ESX-1_EspG PF14011.6 EGD88889.1 - 0.5 9.9 3.9 0.85 9.2 2.0 2.3 2 0 0 2 2 2 0 EspG family Transp_cyt_pur PF02133.15 EGD88890.2 - 2.2e-87 293.6 29.9 2.7e-87 293.4 29.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin GFO_IDH_MocA PF01408.22 EGD88891.1 - 4.8e-15 56.4 0.0 7.3e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGD88891.1 - 9.3e-06 25.6 0.0 0.00012 22.0 0.0 2.4 2 1 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EGD88891.1 - 0.0034 18.0 0.2 0.0063 17.2 0.2 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ADSL_C PF10397.9 EGD88891.1 - 0.17 12.5 0.3 9 6.9 0.0 2.3 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus Methyltransf_2 PF00891.18 EGD88892.1 - 6.3e-27 94.2 0.0 1e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGD88892.1 - 0.0032 17.4 0.1 0.0069 16.3 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain PDZ_3 PF17815.1 EGD88892.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain SLATT_3 PF18184.1 EGD88893.2 - 0.13 12.4 0.1 0.13 12.4 0.1 3.6 5 1 0 5 5 5 0 SMODS and SLOG-associating 2TM effector domain 3 GDPD PF03009.17 EGD88894.2 - 6.6e-66 222.7 0.0 1.4e-65 221.6 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EGD88894.2 - 3.6e-25 88.4 0.2 3.2e-07 30.8 0.4 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD88894.2 - 2.2e-23 82.3 0.8 3.7e-08 33.8 0.1 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EGD88894.2 - 4.2e-17 61.7 3.7 0.0036 17.7 0.0 5.9 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EGD88894.2 - 1.4e-14 53.9 0.1 3.3e-05 24.1 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD88894.2 - 3.8e-14 51.4 0.7 0.031 14.8 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat PRMT5_TIM PF17285.2 EGD88895.1 - 2.4e-71 239.9 0.0 3.7e-71 239.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 EGD88895.1 - 4.1e-65 218.8 0.0 6.2e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EGD88895.1 - 3.8e-58 196.2 0.1 8e-58 195.2 0.1 1.6 1 0 0 1 1 1 1 PRMT5 oligomerisation domain OB_NTP_bind PF07717.16 EGD88896.2 - 5e-21 74.9 0.0 1.2e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EGD88896.2 - 4.9e-19 68.6 0.0 1.2e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGD88896.2 - 2.6e-10 40.6 0.0 6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGD88896.2 - 0.011 15.5 0.1 0.021 14.6 0.1 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 EGD88896.2 - 0.029 14.3 0.1 0.057 13.4 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain MapZ_EC1 PF18041.1 EGD88897.1 - 0.045 14.0 0.4 0.19 12.0 0.4 2.0 1 0 0 1 1 1 0 MapZ extracellular domain 1 Syntaxin_2 PF14523.6 EGD88897.1 - 6.3 7.2 6.8 2.8 8.3 3.0 2.4 2 1 1 3 3 3 0 Syntaxin-like protein EF-hand_6 PF13405.6 EGD88898.1 - 6.1e-09 35.1 0.8 0.00029 20.5 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGD88898.1 - 1.2e-05 25.7 0.8 6.4e-05 23.3 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGD88898.1 - 0.012 15.1 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 EF hand Met_10 PF02475.16 EGD88899.1 - 2.5e-05 24.1 0.0 6.7e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Met-10+ like-protein MFS_1 PF07690.16 EGD88902.1 - 6e-26 91.2 45.5 1e-21 77.2 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ANAPC4_WD40 PF12894.7 EGD88903.1 - 6.2e-05 23.2 0.0 0.35 11.2 0.0 4.1 2 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGD88903.1 - 6.8e-05 23.6 0.3 0.057 14.3 0.0 4.4 3 1 1 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EGD88903.1 - 0.0064 15.6 0.0 0.69 8.9 0.0 2.3 2 0 0 2 2 2 2 Coatomer WD associated region CNH PF00780.22 EGD88903.1 - 0.0081 15.8 0.1 2.9 7.4 0.1 3.2 3 1 0 3 3 3 1 CNH domain Hira PF07569.11 EGD88903.1 - 0.012 15.4 0.0 1.7 8.3 0.0 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split LCM PF04072.14 EGD88904.1 - 9.1e-18 64.9 0.0 1.4e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 EGD88904.1 - 1.6e-12 47.2 19.6 1.4e-06 28.2 0.0 6.4 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 EGD88904.1 - 6.2e-08 32.7 8.7 0.00079 19.7 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGD88904.1 - 0.0012 18.7 7.5 0.12 12.4 0.0 4.4 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 EGD88904.1 - 0.026 14.5 7.7 1.6 8.8 0.0 4.2 5 0 0 5 5 5 0 Kelch motif DSPc PF00782.20 EGD88906.2 - 1.9e-06 27.7 0.0 0.00013 21.7 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Zfx_Zfy_act PF04704.13 EGD88907.2 - 0.059 12.5 0.1 0.076 12.1 0.1 1.1 1 0 0 1 1 1 0 Zfx / Zfy transcription activation region RSN1_TM PF13967.6 EGD88907.2 - 0.076 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Mlh1_C PF16413.5 EGD88908.2 - 2.1e-104 348.7 0.0 2.5e-104 348.4 0.0 1.0 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus Tgi2PP PF18250.1 EGD88910.2 - 0.17 12.1 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Effector immunity protein Tgi2PP RPN1_RPN2_N PF17781.1 EGD88911.2 - 6.8e-118 393.6 4.4 1.2e-117 392.7 4.4 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EGD88911.2 - 6.6e-26 90.1 0.0 1.4e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EGD88911.2 - 1.4e-20 72.6 12.9 7.5e-05 23.0 0.1 8.2 7 0 0 7 7 7 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGD88911.2 - 0.0037 17.6 1.9 3.5 8.1 0.0 4.3 5 2 1 6 6 6 3 HEAT repeats TetR_C_35 PF18556.1 EGD88912.2 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain Cyclin PF08613.11 EGD88915.2 - 3.9e-13 50.1 0.9 1.1e-12 48.7 0.9 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGD88915.2 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyr_redox_2 PF07992.14 EGD88923.1 - 1.1e-52 179.1 0.1 1.5e-52 178.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGD88923.1 - 2.2e-10 41.0 0.0 3.6e-09 37.1 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGD88923.1 - 0.0042 16.4 0.1 3.9 6.6 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EcoR124_C PF12008.8 EGD88923.1 - 0.026 14.2 0.8 0.081 12.6 0.0 1.9 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal PRIMA1 PF16101.5 EGD88923.1 - 0.5 10.4 7.5 1.2 9.2 7.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Trp_oprn_chp PF09534.10 EGD88924.2 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4381 PF14316.6 EGD88924.2 - 0.22 11.7 0.1 0.36 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Acetyltransf_1 PF00583.25 EGD88925.2 - 5.9e-10 39.4 0.0 9.8e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGD88925.2 - 8.3e-10 39.0 0.1 1.5e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGD88925.2 - 8.6e-10 38.6 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGD88925.2 - 3.7e-06 27.0 0.0 0.0038 17.3 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD88925.2 - 1.8e-05 24.6 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGD88925.2 - 0.011 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Arrestin_C PF02752.22 EGD88926.2 - 4.7e-15 56.2 0.3 2.1e-14 54.1 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGD88926.2 - 0.00034 20.7 0.0 0.0015 18.6 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain RRM_1 PF00076.22 EGD88928.1 - 3.6e-59 196.5 0.0 1.2e-20 73.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGD88928.1 - 3.2e-08 33.2 0.0 0.00017 21.2 0.0 2.8 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGD88928.1 - 2.3e-07 30.5 0.0 0.0089 15.9 0.0 3.5 3 1 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGD88928.1 - 7.5e-05 22.7 0.1 3.6 7.7 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 EGD88928.1 - 0.0006 20.0 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 2 RRM-like domain Cas_Cas2CT1978 PF09707.10 EGD88928.1 - 0.0016 18.4 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM PF05172.13 EGD88928.1 - 0.0017 18.3 0.0 15 5.7 0.0 3.3 2 1 1 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EGD88928.1 - 0.013 15.6 0.0 11 6.2 0.0 3.3 3 0 0 3 3 3 0 RNA recognition motif SET_assoc PF11767.8 EGD88928.1 - 0.16 11.6 0.0 26 4.5 0.0 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated PIG-Y PF15159.6 EGD88930.2 - 1e-23 84.0 8.6 1.8e-23 83.2 8.6 1.4 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF2956 PF11169.8 EGD88930.2 - 0.25 11.5 0.2 0.25 11.5 0.2 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF2956) DUF1218 PF06749.12 EGD88930.2 - 0.75 10.4 5.4 5.3 7.6 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) GREB1 PF15782.5 EGD88930.2 - 7.4 3.5 14.7 9.2 3.2 14.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GATase_4 PF13230.6 EGD88931.1 - 1.5e-14 53.6 0.0 9.9e-13 47.6 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EGD88931.1 - 4.6e-07 30.1 0.0 7.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Dynamin_N PF00350.23 EGD88933.1 - 1.1e-44 152.4 0.0 2.6e-44 151.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGD88933.1 - 2.6e-12 46.5 0.0 5.4e-10 39.0 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EGD88933.1 - 3.1e-05 24.0 0.0 8.4e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGD88933.1 - 0.0016 18.8 0.5 0.062 13.7 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_15 PF13175.6 EGD88933.1 - 0.011 15.5 0.7 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 EGD88933.1 - 0.038 13.8 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Ribosomal_S6 PF01250.17 EGD88934.1 - 5.7e-23 81.0 0.0 7.4e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 GCV_H PF01597.19 EGD88935.1 - 4e-40 136.5 1.4 4.8e-40 136.3 1.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 EGD88935.1 - 0.00071 19.5 0.1 0.001 19.0 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 EGD88935.1 - 0.0078 16.0 1.0 0.026 14.4 0.6 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme zf-rbx1 PF12678.7 EGD88936.1 - 3.3e-09 36.9 3.8 9.4e-09 35.4 3.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGD88936.1 - 3.8e-08 33.5 8.1 1.2e-07 32.0 4.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGD88936.1 - 5.2e-07 29.4 2.3 5.2e-07 29.4 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGD88936.1 - 1.3e-06 28.2 3.6 3.6e-06 26.8 3.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGD88936.1 - 1.2e-05 25.1 2.1 2.1e-05 24.3 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGD88936.1 - 0.00011 22.0 5.4 0.00012 21.8 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD88936.1 - 0.00013 21.9 4.2 0.00029 20.8 0.7 2.9 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGD88936.1 - 0.00016 21.5 3.5 0.0002 21.2 1.4 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EGD88936.1 - 0.0023 17.7 10.6 0.0025 17.5 0.8 3.3 3 0 0 3 3 3 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGD88936.1 - 0.013 15.1 1.6 0.013 15.1 1.6 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EGD88936.1 - 0.031 14.3 4.9 0.12 12.4 4.9 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.8 EGD88936.1 - 0.05 11.4 1.1 0.093 10.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) PQ-loop PF04193.14 EGD88936.1 - 0.59 9.9 7.1 2.2 8.1 1.7 2.9 2 0 0 2 2 2 0 PQ loop repeat FANCL_C PF11793.8 EGD88936.1 - 2.7 8.2 5.9 5.1 7.3 3.5 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain Cation_efflux PF01545.21 EGD88937.1 - 2e-14 53.8 11.1 2.7e-14 53.4 11.1 1.1 1 0 0 1 1 1 1 Cation efflux family COMPASS-Shg1 PF05205.12 EGD88940.1 - 5.1e-26 91.4 0.1 5.1e-26 91.4 0.1 1.9 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF4E PF01652.18 EGD88941.1 - 1.3e-29 103.1 0.2 1.6e-29 102.7 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2517 PF10725.9 EGD88941.1 - 0.066 13.0 0.1 2.2 8.1 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2517) 2Fe-2S_thioredx PF01257.19 EGD88941.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin DUF4598 PF15370.6 EGD88942.2 - 3e-13 50.2 0.2 3e-13 50.2 0.2 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4598) DNA_pol_phi PF04931.13 EGD88942.2 - 3.9 5.5 7.0 4.5 5.2 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi IF3_N PF05198.16 EGD88944.1 - 8.3e-11 42.0 1.2 2.7e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 EGD88944.1 - 3.4e-10 39.7 0.8 5.9e-10 39.0 0.8 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 EGD88944.1 - 7.5e-07 29.0 1.7 9.7e-06 25.4 1.3 2.1 1 1 1 2 2 2 1 Mitochondrial translation initiation factor GTP_EFTU PF00009.27 EGD88945.1 - 8.7e-58 195.1 0.0 1.2e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGD88945.1 - 2.3e-21 76.2 0.0 4.7e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGD88945.1 - 2.6e-17 63.0 1.7 6.3e-17 61.7 1.7 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGD88945.1 - 2.9e-05 24.1 0.0 6.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EGD88945.1 - 0.015 14.9 0.2 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EGD88945.1 - 0.034 14.1 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 EGD88945.1 - 0.035 13.8 0.2 6.6 6.5 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SCAB-ABD PF16711.5 EGD88945.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein Radical_SAM PF04055.21 EGD88946.1 - 2.2e-05 24.9 0.0 3.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily bZIP_1 PF00170.21 EGD88949.1 - 0.00018 21.5 12.2 0.00033 20.7 12.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF2205 PF10224.9 EGD88949.1 - 0.17 11.9 5.8 0.42 10.7 5.8 1.7 1 0 0 1 1 1 0 Short coiled-coil protein GvpL_GvpF PF06386.11 EGD88949.1 - 1.1 9.2 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF ABM PF03992.16 EGD88950.1 - 0.07 13.2 0.1 1.3 9.2 0.0 2.6 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.16 EGD88951.1 - 2.1e-40 138.8 54.6 2.1e-40 138.8 54.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGD88951.1 - 4.5e-17 61.7 27.2 5.8e-17 61.3 27.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 EGD88952.2 - 0.0027 16.8 1.6 0.01 14.9 0.0 2.7 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD88952.2 - 0.017 15.2 2.7 0.049 13.8 2.7 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Androgen_recep PF02166.16 EGD88952.2 - 0.1 11.4 15.2 0.16 10.8 15.2 1.2 1 0 0 1 1 1 0 Androgen receptor PAT1 PF09770.9 EGD88952.2 - 0.12 10.7 11.8 0.17 10.1 11.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 EGD88952.2 - 0.77 9.3 21.1 1.4 8.5 21.1 1.4 1 0 0 1 1 1 0 Spt20 family Paired_CXXCH_1 PF09699.10 EGD88952.2 - 0.86 9.4 5.6 4.4 7.1 0.5 2.5 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Plasmodium_Vir PF05795.11 EGD88952.2 - 1.2 8.5 6.0 0.23 10.8 2.4 1.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF4834 PF16118.5 EGD88952.2 - 1.4 9.9 4.6 3.8 8.5 4.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Activator_LAG-3 PF11498.8 EGD88952.2 - 1.6 7.6 26.4 2.7 6.9 26.4 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 EGD88952.2 - 1.9 8.4 19.7 3.5 7.5 19.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SKA1 PF07160.12 EGD88952.2 - 5.7 6.7 10.4 90 2.8 0.0 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 MFS_1 PF07690.16 EGD88954.1 - 3.6e-31 108.4 45.5 1.5e-30 106.3 44.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD88954.1 - 1.7e-10 40.3 11.8 1.7e-10 40.3 11.8 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EGD88954.1 - 0.00029 19.3 1.0 0.00067 18.1 1.0 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family RHD3 PF05879.12 EGD88955.2 - 3.5e-191 637.2 0.0 4.1e-191 636.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) DIM1 PF02966.16 EGD88956.2 - 1.7e-66 222.0 0.3 2.7e-66 221.4 0.3 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EGD88956.2 - 0.017 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin 4HBT_2 PF13279.6 EGD88957.2 - 0.0022 18.5 0.0 0.0024 18.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily HIG_1_N PF04588.13 EGD88958.1 - 2.8e-06 27.4 0.2 2.8e-06 27.4 0.2 2.0 3 0 0 3 3 3 1 Hypoxia induced protein conserved region Med26 PF08711.11 EGD88961.2 - 8.5e-10 38.5 0.0 1.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Tom5 PF10642.9 EGD88962.1 - 1.2e-19 70.1 0.1 1.3e-19 70.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.6 EGD88963.1 - 1.1e-41 142.2 0.3 1.1e-41 142.2 0.3 2.9 3 1 0 3 3 3 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 EGD88963.1 - 9.4e-13 47.5 1.3 1.6e-12 46.7 1.3 1.4 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 EGD88963.1 - 1.6e-08 35.3 36.7 1.6e-08 35.3 36.7 2.6 1 1 1 2 2 2 1 Nucleoporin FG repeat region Fib_alpha PF08702.10 EGD88963.1 - 0.0027 17.9 0.7 0.0027 17.9 0.7 2.0 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family AAA_lid_10 PF17872.1 EGD88964.2 - 1.4e-12 47.6 0.5 4.1e-12 46.1 0.5 1.7 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 EGD88964.2 - 1.4e-07 32.0 0.0 4.4e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) WD40 PF00400.32 EGD88965.1 - 2.2e-43 145.4 14.4 9.8e-10 38.9 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD88965.1 - 1.6e-05 25.1 0.4 1.7 9.0 0.0 4.6 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD88965.1 - 0.014 14.1 1.8 9.6 4.7 0.0 3.8 1 1 3 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 EGD88965.1 - 0.27 10.5 0.0 1.1 8.5 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain Ank_2 PF12796.7 EGD88966.2 - 7.2e-41 138.7 0.7 1.8e-14 54.1 0.1 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD88966.2 - 1.3e-34 118.1 3.9 6e-09 36.3 0.0 5.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGD88966.2 - 7.5e-31 105.8 0.4 5.9e-09 36.0 0.0 4.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD88966.2 - 4.4e-27 91.2 0.4 0.00084 19.6 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 EGD88966.2 - 1.1e-20 73.1 1.0 0.002 18.5 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Shal-type PF11601.8 EGD88966.2 - 0.15 11.6 0.9 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels, N-terminal TMF_TATA_bd PF12325.8 EGD88967.1 - 5e-40 136.3 13.4 5e-40 136.3 13.4 7.0 3 1 3 7 7 7 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EGD88967.1 - 6.4e-23 80.5 19.0 6.4e-23 80.5 19.0 8.2 5 3 2 7 7 7 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EGD88967.1 - 5e-05 23.6 3.4 5e-05 23.6 3.4 6.1 3 1 3 6 6 6 2 Autophagy protein 16 (ATG16) FH2 PF02181.23 EGD88967.1 - 0.0053 15.9 1.9 0.0053 15.9 1.9 5.0 3 2 2 5 5 5 1 Formin Homology 2 Domain Muted PF14942.6 EGD88967.1 - 0.013 15.9 6.5 0.013 15.9 6.5 6.1 2 1 5 8 8 8 0 Organelle biogenesis, Muted-like protein Pkinase PF00069.25 EGD88968.1 - 7e-07 28.9 0.0 8.6e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD88968.1 - 8e-06 25.3 0.0 4.6e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PemK_toxin PF02452.17 EGD88968.1 - 0.16 12.4 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system Phlebovirus_NSM PF07246.11 EGD88970.1 - 0.0031 16.9 8.9 0.0031 16.9 8.9 2.7 3 0 0 3 3 3 1 Phlebovirus nonstructural protein NS-M ATG16 PF08614.11 EGD88970.1 - 0.014 15.7 6.7 0.014 15.7 6.7 5.4 4 1 1 5 5 5 0 Autophagy protein 16 (ATG16) MCC-bdg_PDZ PF10506.9 EGD88970.1 - 0.078 13.0 13.0 1.7 8.7 2.2 4.9 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Apq12 PF12716.7 EGD88973.2 - 2.1e-21 75.6 11.9 3.1e-21 75.1 11.9 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis S-AdoMet_synt_C PF02773.16 EGD88975.1 - 7.3e-66 220.4 1.0 9.7e-66 220.0 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 EGD88975.1 - 2.8e-44 149.8 0.1 7.1e-44 148.5 0.1 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 EGD88975.1 - 1.1e-35 122.5 0.0 2e-35 121.6 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 EGD88975.1 - 0.048 12.5 0.2 0.52 9.1 0.1 2.2 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) SLD3 PF08639.10 EGD88976.1 - 1.7e-155 518.9 10.9 1.7e-155 518.9 10.9 1.7 2 0 0 2 2 2 1 DNA replication regulator SLD3 CRC_subunit PF08624.10 EGD88978.2 - 2.7e-52 176.8 0.2 3.9e-52 176.3 0.2 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Sporozoite_P67 PF05642.11 EGD88979.1 - 3.1 5.8 9.0 4.1 5.4 9.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_C97 PF05903.14 EGD88982.2 - 0.00094 19.0 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Homeodomain PF00046.29 EGD88983.1 - 1.3e-16 60.2 1.5 1.5e-15 56.8 2.7 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 EGD88983.1 - 0.00041 20.2 1.1 0.0013 18.6 1.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain DUF4638 PF15472.6 EGD88983.1 - 0.12 12.1 5.0 0.21 11.3 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Dicty_REP PF05086.12 EGD88983.1 - 9.7 4.0 7.5 14 3.5 7.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HAD_2 PF13419.6 EGD88985.1 - 5.5e-21 75.4 0.0 7.5e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGD88985.1 - 3.1e-10 40.7 0.2 3.2e-06 27.6 0.0 2.8 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGD88985.1 - 3.3e-05 24.4 0.0 4.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGD88985.1 - 0.00051 20.0 0.1 0.0013 18.8 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EGD88985.1 - 0.0023 18.0 0.2 0.1 12.7 0.1 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase CBFD_NFYB_HMF PF00808.23 EGD88987.1 - 5.7e-06 26.5 0.0 9.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SIR2 PF02146.17 EGD88988.2 - 2.9e-14 53.4 0.0 1.8e-13 50.8 0.0 2.1 2 1 0 2 2 2 1 Sir2 family Ribosomal_L29 PF00831.23 EGD88990.2 - 6.4e-18 64.5 0.3 6.4e-18 64.5 0.3 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein Cortex-I_coil PF09304.10 EGD88990.2 - 0.33 11.2 5.0 0.36 11.1 1.4 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil CorA PF01544.18 EGD88990.2 - 0.39 10.0 2.1 0.5 9.6 2.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V-SNARE_C PF12352.8 EGD88991.1 - 3.4e-15 56.1 0.1 3.4e-15 56.1 0.1 2.8 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EGD88991.1 - 0.033 14.1 3.0 6 6.9 0.0 3.2 2 1 2 4 4 4 0 Sec20 GOLGA2L5 PF15070.6 EGD88991.1 - 0.035 12.8 4.7 0.05 12.3 4.7 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DUF4570 PF15134.6 EGD88991.1 - 0.71 9.9 5.4 1.7 8.7 5.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) SATase_N PF06426.14 EGD88991.1 - 1 9.8 3.5 3.1 8.2 1.6 2.4 1 1 1 2 2 2 0 Serine acetyltransferase, N-terminal ATP-synt_10 PF05176.14 EGD88992.1 - 3.3e-77 259.2 0.0 4.6e-77 258.7 0.0 1.2 1 0 0 1 1 1 1 ATP10 protein DNA_pol_B_palm PF14792.6 EGD88993.1 - 1.7e-32 112.0 0.0 3.4e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EGD88993.1 - 9.7e-23 80.1 0.0 2.2e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EGD88993.1 - 4.9e-20 71.1 0.6 1.6e-19 69.4 0.3 2.1 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EGD88993.1 - 5.5e-18 65.1 0.5 1.2e-17 64.0 0.5 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 EGD88993.1 - 0.0026 18.0 0.0 0.0082 16.4 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.6 EGD88993.1 - 0.035 14.7 0.1 11 6.7 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain Cdd1 PF11731.8 EGD88993.1 - 0.05 13.9 0.0 1.1 9.5 0.0 3.0 3 1 1 4 4 4 0 Pathogenicity locus ACOX PF01756.19 EGD88995.2 - 0.032 13.8 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA oxidase CPL PF08144.11 EGD88997.1 - 6.3e-34 117.4 0.0 4.9e-29 101.5 0.0 3.8 4 0 0 4 4 4 2 CPL (NUC119) domain RRN3 PF05327.11 EGD88997.1 - 0.23 10.0 10.8 8.1 4.9 8.7 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EGD88997.1 - 0.35 9.1 16.3 0.61 8.3 16.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 EGD88997.1 - 2.7 6.0 15.1 4.4 5.3 15.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 EGD88997.1 - 7.4 4.6 24.5 12 3.9 24.5 1.2 1 0 0 1 1 1 0 Nop14-like family Rad51 PF08423.11 EGD89000.1 - 2e-128 427.0 0.0 2.5e-128 426.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EGD89000.1 - 1.2e-09 38.0 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EGD89000.1 - 5.5e-08 32.6 0.0 7.5e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EGD89000.1 - 2.5e-05 24.8 1.1 6.2e-05 23.5 0.5 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EGD89000.1 - 0.00012 21.6 0.7 0.00054 19.4 0.7 2.0 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EGD89000.1 - 0.0085 15.5 0.1 0.04 13.2 0.0 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain HHH PF00633.23 EGD89000.1 - 0.021 14.7 0.4 11 6.1 0.1 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif ssDNA_TraI_N PF18272.1 EGD89000.1 - 0.043 13.8 0.7 0.21 11.6 0.1 2.3 3 0 0 3 3 3 0 single-stranded DNA binding TraI N-terminal subdomain PAXNEB PF05625.11 EGD89000.1 - 0.091 11.9 0.2 0.33 10.0 0.0 1.8 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.8 EGD89001.1 - 1.1e-132 443.5 7.6 1.6e-132 442.9 7.6 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 MFS_1 PF07690.16 EGD89002.2 - 8.1e-38 130.2 29.0 8.1e-38 130.2 29.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD89002.2 - 8.2e-08 31.5 6.6 8.2e-08 31.5 6.6 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EGD89002.2 - 1.7e-06 26.8 2.8 1.7e-06 26.8 2.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2_3 PF16080.5 EGD89002.2 - 0.031 14.0 0.2 0.18 11.6 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DUF3808 PF10300.9 EGD89003.2 - 2.1e-58 198.2 0.0 2.3e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.13 EGD89004.1 - 1.7e-21 76.0 13.5 2.2e-21 75.7 13.5 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 EGD89004.1 - 0.089 12.6 3.3 0.1 12.5 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) PGK PF00162.19 EGD89005.1 - 1.7e-148 494.6 0.3 1.9e-148 494.5 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 EGD89005.1 - 0.0026 17.7 0.9 0.075 13.1 0.0 3.1 3 0 0 3 3 3 1 PA domain DUF3530 PF12048.8 EGD89005.1 - 0.21 11.0 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) zf-C2H2 PF00096.26 EGD89006.1 - 1.2e-08 35.0 6.0 1.2e-05 25.5 0.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGD89006.1 - 2.3e-08 34.1 8.4 7.7e-07 29.3 0.7 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGD89006.1 - 4.2e-07 29.8 0.9 0.017 15.1 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGD89006.1 - 3.1e-05 24.4 6.8 0.002 18.8 0.4 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 EGD89006.1 - 0.00016 22.2 10.2 0.083 13.5 0.1 3.7 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 EGD89006.1 - 0.046 13.5 1.1 0.092 12.5 0.1 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 EGD89006.1 - 0.14 12.0 3.8 0.32 10.8 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 EGD89006.1 - 0.18 12.1 2.9 2.7 8.4 0.2 3.4 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EGD89006.1 - 0.24 11.7 3.5 1.5 9.2 0.5 2.4 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zap1_zf2 PF18217.1 EGD89006.1 - 0.58 10.2 6.9 3.2 7.8 0.7 2.6 2 0 0 2 2 2 0 Zap1 zinc finger 2 zf_ZIC PF18366.1 EGD89006.1 - 0.66 10.1 3.4 1 9.5 0.1 2.9 3 0 0 3 3 3 0 Zic proteins zinc finger domain SNF2_N PF00176.23 EGD89007.1 - 4.8e-56 190.0 0.0 1.1e-55 188.7 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.24 EGD89007.1 - 1.2e-24 85.9 0.4 1.6e-15 56.7 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 EGD89007.1 - 3.1e-21 75.6 0.0 2.8e-20 72.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 EGD89007.1 - 6.5e-18 65.1 0.0 2.2e-17 63.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 EGD89007.1 - 1.9e-06 28.2 6.9 4.6e-06 26.9 2.1 4.5 4 1 1 5 5 5 2 Chromodomain helicase DNA-binding domain 1 HDA2-3 PF11496.8 EGD89007.1 - 3e-06 26.6 0.0 1e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EGD89007.1 - 1.3e-05 25.3 0.2 0.00017 21.7 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 EGD89007.1 - 0.013 15.6 0.2 0.15 12.2 0.0 2.9 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain SLIDE PF09111.10 EGD89007.1 - 0.041 13.9 0.0 0.42 10.7 0.0 2.8 1 1 1 2 2 2 0 SLIDE AAA_22 PF13401.6 EGD89007.1 - 0.059 13.6 0.0 0.28 11.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain CDH1_2_SANT_HL1 PF18375.1 EGD89007.1 - 0.096 13.4 1.1 0.63 10.7 1.1 2.5 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 ABC_tran PF00005.27 EGD89008.2 - 5.7e-34 117.6 0.0 1.9e-15 57.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 EGD89008.2 - 3.5e-14 52.3 5.5 3.5e-14 52.3 5.5 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 EGD89008.2 - 4.2e-11 42.7 2.4 0.003 17.0 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGD89008.2 - 3.8e-09 36.8 6.0 0.31 10.8 1.8 4.5 3 2 2 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 EGD89008.2 - 1.9e-06 27.9 0.0 0.047 13.6 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA PF00004.29 EGD89008.2 - 1.9e-05 25.1 0.1 0.021 15.2 0.1 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EGD89008.2 - 3.4e-05 23.7 0.4 0.23 11.1 0.0 3.0 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EGD89008.2 - 4.8e-05 23.7 0.0 0.0099 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.27 EGD89008.2 - 8.6e-05 22.2 2.5 8.6e-05 22.2 2.5 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_16 PF13191.6 EGD89008.2 - 0.00014 22.3 0.0 0.038 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EGD89008.2 - 0.00036 20.1 1.1 0.0036 16.8 0.2 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EGD89008.2 - 0.0004 20.7 0.3 0.26 11.7 0.0 3.1 4 0 0 4 4 2 1 RNA helicase RsgA_GTPase PF03193.16 EGD89008.2 - 0.00059 19.8 0.2 0.98 9.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGD89008.2 - 0.0013 18.5 0.4 0.99 9.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EGD89008.2 - 0.0013 19.3 0.1 2.1 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGD89008.2 - 0.0019 18.0 2.1 0.12 12.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 EGD89008.2 - 0.003 17.7 11.4 0.0058 16.7 11.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain SRP54 PF00448.22 EGD89008.2 - 0.003 17.2 2.9 0.065 12.9 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.7 EGD89008.2 - 0.0044 17.0 12.3 0.0092 16.0 2.2 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain TsaE PF02367.17 EGD89008.2 - 0.0058 16.6 0.1 0.089 12.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EGD89008.2 - 0.0066 16.4 2.1 0.32 10.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 EGD89008.2 - 0.0067 15.6 1.6 1.6 7.8 0.0 3.4 3 1 1 4 4 4 1 NB-ARC domain Thymidylate_kin PF02223.17 EGD89008.2 - 0.0098 15.6 0.2 4.9 6.8 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase AAA_33 PF13671.6 EGD89008.2 - 0.012 15.8 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGD89008.2 - 0.015 15.0 0.4 0.68 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_10 PF13237.6 EGD89008.2 - 0.027 14.6 1.6 0.027 14.6 1.6 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_5 PF07728.14 EGD89008.2 - 0.03 14.3 0.1 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EGD89008.2 - 0.031 14.8 2.8 0.62 10.5 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGD89008.2 - 0.031 14.5 0.1 4.6 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EGD89008.2 - 0.036 12.7 0.0 0.075 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EGD89008.2 - 0.066 12.6 0.1 0.36 10.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein VirE PF05272.11 EGD89008.2 - 0.072 12.8 0.0 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_16 PF13484.6 EGD89008.2 - 0.088 13.8 0.2 0.088 13.8 0.2 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 EGD89008.2 - 0.097 12.9 11.5 0.22 11.7 11.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain DnaB_C PF03796.15 EGD89008.2 - 0.11 11.8 0.0 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Fer4_17 PF13534.6 EGD89008.2 - 0.14 12.7 0.2 0.14 12.7 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain ATPase PF06745.13 EGD89008.2 - 0.2 11.0 0.1 0.42 9.9 0.1 1.5 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.9 EGD89008.2 - 0.29 10.9 2.3 0.3 10.8 0.1 2.2 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 EGD89008.2 - 0.47 10.4 3.2 4.8 7.0 0.1 2.8 3 0 0 3 3 2 0 NTPase Fer4_7 PF12838.7 EGD89008.2 - 1.1 9.9 12.9 0.087 13.4 1.6 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 EGD89008.2 - 2.3 8.5 9.9 0.3 11.3 1.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 EGD89008.2 - 7.2 7.1 11.3 1.5 9.4 2.1 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain FF PF01846.19 EGD89009.2 - 2e-56 188.0 15.5 1.3e-14 54.1 0.0 7.1 6 1 0 6 6 6 5 FF domain HycH PF07450.11 EGD89009.2 - 0.046 14.1 0.6 0.2 12.0 0.6 2.2 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH EMP24_GP25L PF01105.24 EGD89009.2 - 0.13 12.2 1.4 0.35 10.8 1.4 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SesA PF17107.5 EGD89009.2 - 5.8 7.1 8.8 0.55 10.4 0.6 3.3 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Trs65 PF12735.7 EGD89010.1 - 5.9e-87 292.0 0.0 1.5e-86 290.7 0.0 1.6 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.12 EGD89011.1 - 7.8e-19 67.7 0.1 1.8e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.16 EGD89012.1 - 3.9e-29 101.7 32.5 7.6e-28 97.4 30.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EGD89013.2 - 2.2e-49 168.5 0.0 2.3e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4485 PF14846.6 EGD89013.2 - 0.99 9.5 2.8 1.2 9.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4485) Amidase PF01425.21 EGD89014.1 - 2.4e-109 366.3 0.0 3.3e-109 365.8 0.0 1.2 1 0 0 1 1 1 1 Amidase IBB PF01749.20 EGD89015.2 - 2.2e-28 98.5 0.5 2.9e-28 98.2 0.5 1.2 1 0 0 1 1 1 1 Importin beta binding domain NUSAP PF16006.5 EGD89015.2 - 0.051 13.3 7.8 0.067 12.9 7.8 1.1 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein POT1PC PF16686.5 EGD89016.2 - 7.1e-47 159.2 2.5 8.7e-46 155.6 2.6 2.3 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 EGD89016.2 - 1.8e-19 70.0 0.0 6.6e-19 68.2 0.0 2.0 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 zf-CCCH_4 PF18044.1 EGD89017.1 - 1.1 9.2 10.3 0.36 10.7 2.1 2.8 2 0 0 2 2 2 0 CCCH-type zinc finger TRAP_alpha PF03896.16 EGD89018.1 - 4.8e-14 52.2 0.0 1.6e-13 50.6 0.0 1.7 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit HA2 PF04408.23 EGD89019.1 - 4.9e-17 62.2 0.6 1.1e-16 61.0 0.0 1.9 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGD89019.1 - 1.4e-14 54.2 0.0 2.8e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGD89019.1 - 6e-14 52.3 0.0 1.3e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 EGD89019.1 - 2.3e-10 40.8 0.1 5.9e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 EGD89019.1 - 2.5e-10 40.4 0.0 4.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DND1_DSRM PF14709.7 EGD89019.1 - 0.0023 18.1 0.0 0.0069 16.6 0.0 1.8 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.6 EGD89019.1 - 0.0041 17.4 0.7 0.026 14.8 0.7 2.4 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGD89019.1 - 0.0099 15.0 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 EGD89019.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 KaiC UBA PF00627.31 EGD89019.1 - 0.028 14.3 0.0 0.22 11.5 0.0 2.5 3 0 0 3 3 3 0 UBA/TS-N domain AAA_29 PF13555.6 EGD89019.1 - 0.031 14.0 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGD89019.1 - 0.041 14.4 0.0 0.14 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain dsRBD2 PF17842.1 EGD89019.1 - 0.057 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 CoA_trans PF01144.23 EGD89019.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase PhoH PF02562.16 EGD89019.1 - 0.16 11.4 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF1359 PF07097.11 EGD89020.1 - 0.098 12.9 0.2 2.6 8.3 0.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1359) HupE_UreJ PF04955.12 EGD89020.1 - 0.48 9.9 4.6 0.16 11.5 1.5 1.8 2 0 0 2 2 2 0 HupE / UreJ protein Arylsulfotran_2 PF14269.6 EGD89022.2 - 4.1e-63 213.5 0.1 6.6e-63 212.8 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EGD89022.2 - 1.5e-13 50.4 0.0 2.2e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) RHS PF03527.14 EGD89022.2 - 0.088 12.6 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 RHS protein Fungal_trans PF04082.18 EGD89025.1 - 1.1e-19 70.6 3.1 1.9e-19 69.7 3.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EGD89025.1 - 3.5e-07 30.3 13.4 7.8e-05 22.9 5.5 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGD89025.1 - 0.013 16.3 14.8 0.83 10.7 1.3 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGD89025.1 - 0.015 15.7 18.3 0.27 11.8 7.6 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EGD89025.1 - 0.088 13.5 3.8 0.74 10.5 0.0 3.0 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-CHY PF05495.12 EGD89025.1 - 1 9.9 6.5 0.82 10.2 3.5 2.2 2 0 0 2 2 2 0 CHY zinc finger UPRTase PF14681.6 EGD89027.1 - 2.9e-71 239.2 0.0 3.4e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGD89027.1 - 9.1e-07 28.5 0.0 1.6e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.15 EGD89028.1 - 8.3e-40 135.0 12.1 4.9e-23 81.3 6.6 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DUF4234 PF14018.6 EGD89029.2 - 0.032 14.4 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) OATP PF03137.20 EGD89029.2 - 0.13 10.5 0.1 0.16 10.2 0.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family JAB PF01398.21 EGD89030.2 - 1.9e-29 102.0 0.0 3e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EGD89030.2 - 1.1e-24 87.2 0.0 2e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EGD89030.2 - 0.001 18.8 0.0 0.0022 17.7 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.25 EGD89031.1 - 7.2e-23 81.3 0.0 9.8e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD89031.1 - 5.3e-18 65.2 0.0 1e-17 64.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGD89031.1 - 0.0002 20.8 0.1 0.0003 20.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGD89031.1 - 0.014 14.9 0.0 0.043 13.4 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase MAP65_ASE1 PF03999.12 EGD89033.2 - 1e-69 235.8 30.4 4.8e-69 233.6 30.5 1.9 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) CC2-LZ PF16516.5 EGD89033.2 - 0.046 14.1 3.2 1.7 9.1 1.4 3.2 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spectrin PF00435.21 EGD89033.2 - 0.1 13.1 5.9 0.27 11.8 0.6 3.3 3 0 0 3 3 3 0 Spectrin repeat Occludin_ELL PF07303.13 EGD89033.2 - 0.37 11.5 2.9 2.9 8.7 0.1 3.4 2 2 1 3 3 3 0 Occludin homology domain tRNA-synt_1c PF00749.21 EGD89034.2 - 5.1e-44 150.4 0.0 1.7e-43 148.8 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 EGD89035.2 - 2.6e-39 134.7 0.4 4.6e-39 133.9 0.4 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGD89035.2 - 8.8e-24 83.4 5.8 1.7e-23 82.5 5.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGD89035.2 - 1.6e-12 47.6 19.0 2.9e-12 46.7 19.0 1.5 1 0 0 1 1 1 1 DnaJ central domain zf-RING_10 PF16685.5 EGD89035.2 - 2.2 8.5 5.9 17 5.6 0.6 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF1356 PF07092.12 EGD89035.2 - 9 5.5 5.2 15 4.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) 4HBT PF03061.22 EGD89036.2 - 7.2e-08 32.7 0.0 1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 EGD89036.2 - 0.16 12.5 0.0 0.18 12.3 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily PseudoU_synth_2 PF00849.22 EGD89037.1 - 2.1e-25 89.6 0.0 3.4e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EGD89037.1 - 0.072 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 S4 domain Glyco_tran_WecB PF03808.13 EGD89037.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Ribosomal_L32e PF01655.18 EGD89038.2 - 1.4e-48 163.8 4.7 4.9e-48 162.0 0.5 2.2 1 1 1 2 2 2 2 Ribosomal protein L32 Sec2p PF06428.11 EGD89039.2 - 1.4e-10 41.0 14.1 2.1e-10 40.4 14.1 1.3 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p ATG16 PF08614.11 EGD89039.2 - 0.0071 16.6 14.9 0.0071 16.6 14.9 1.8 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 EGD89039.2 - 0.011 13.3 5.1 0.015 12.8 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HAUS6_N PF14661.6 EGD89039.2 - 0.057 13.0 2.8 0.09 12.3 2.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF737 PF05300.11 EGD89039.2 - 0.092 13.1 14.6 0.12 12.7 14.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Cluap1 PF10234.9 EGD89039.2 - 0.099 12.0 9.6 0.072 12.5 8.0 1.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 Spc7 PF08317.11 EGD89039.2 - 0.19 10.6 8.2 0.26 10.1 8.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EGD89039.2 - 0.24 10.9 9.7 0.31 10.6 9.7 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 EGD89039.2 - 0.91 8.8 5.2 1.1 8.6 5.2 1.2 1 0 0 1 1 1 0 FAM76 protein RRM_1 PF00076.22 EGD89040.2 - 3.6e-15 55.5 0.0 7.3e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 EGD89040.2 - 9.7 4.3 7.9 13 3.9 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein XH PF03469.14 EGD89041.1 - 0.067 13.1 0.1 0.094 12.6 0.1 1.2 1 0 0 1 1 1 0 XH domain 2-Hacid_dh_C PF02826.19 EGD89042.1 - 3.3e-55 186.2 0.0 4.3e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGD89042.1 - 2.5e-15 56.3 0.0 3.1e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGD89042.1 - 5.4e-07 29.9 0.0 7.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 EGD89042.1 - 0.00013 22.8 0.0 0.00061 20.6 0.0 2.1 3 1 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 EGD89042.1 - 0.0013 19.3 0.0 0.0026 18.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent zf-C2HE PF16278.5 EGD89043.2 - 4.1e-21 75.2 2.1 4.1e-21 75.2 0.5 1.9 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EGD89043.2 - 6e-15 55.7 2.1 7.8e-13 48.9 2.1 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EGD89043.2 - 1.5e-12 48.1 1.4 4.7e-12 46.5 1.4 1.8 1 1 0 1 1 1 1 HIT domain TFIIA PF03153.13 EGD89044.2 - 0.35 10.8 18.8 0.47 10.4 18.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0524 PF15823.5 EGD89044.2 - 1.6 8.0 6.0 12 5.2 0.3 2.5 2 0 0 2 2 2 0 UPF0524 of C3orf70 Zn_clus PF00172.18 EGD89046.2 - 0.00029 20.9 12.7 0.00057 19.9 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4349 PF14257.6 EGD89046.2 - 0.03 13.8 0.0 0.03 13.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) RNA_pol_Rpc4 PF05132.14 EGD89047.1 - 6.5e-33 114.3 0.0 6.5e-33 114.3 0.0 3.3 1 1 1 2 2 2 1 RNA polymerase III RPC4 KRE1 PF17056.5 EGD89048.1 - 2.7e-06 27.0 0.0 4.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Killer toxin-resistance protein 1 Apt1 PF10351.9 EGD89049.2 - 3.6e-181 603.2 0.1 3.6e-181 603.2 0.1 2.5 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27 PF10344.9 EGD89049.2 - 6.2e-173 577.2 0.0 1.1e-172 576.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.9 EGD89049.2 - 1.7e-168 561.4 1.5 2.6e-168 560.8 1.5 1.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EGD89049.2 - 4.4e-55 186.1 0.1 1.2e-54 184.6 0.0 1.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EGD89049.2 - 1.1e-51 174.8 0.0 2.8e-51 173.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EGD89049.2 - 1.1e-27 96.7 0.0 6.7e-27 94.2 0.0 2.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain CheZ PF04344.13 EGD89049.2 - 0.32 10.9 1.3 5.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Chemotaxis phosphatase, CheZ UQ_con PF00179.26 EGD89052.1 - 7.3e-19 67.8 0.0 1.1e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGD89052.1 - 0.017 15.4 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 RWD domain DHHC PF01529.20 EGD89053.2 - 4.1e-05 23.7 19.5 0.00033 20.8 8.5 2.8 2 1 1 3 3 3 2 DHHC palmitoyltransferase FA_hydroxylase PF04116.13 EGD89053.2 - 0.15 12.4 1.4 1.8 9.0 0.0 2.8 3 0 0 3 3 3 0 Fatty acid hydroxylase superfamily Rhomboid PF01694.22 EGD89054.2 - 3.9e-33 114.6 7.9 3.9e-33 114.6 7.9 2.1 3 0 0 3 3 3 1 Rhomboid family DUF2177 PF09945.9 EGD89054.2 - 0.26 11.4 5.8 0.46 10.6 0.4 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2177) DUF4381 PF14316.6 EGD89054.2 - 8.6 6.6 6.9 0.9 9.8 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) GST_C_2 PF13410.6 EGD89055.2 - 3.7e-05 23.7 0.3 0.00011 22.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Kinetochor_Ybp2 PF08568.10 EGD89056.1 - 1.5e-115 387.1 0.3 1.8e-115 386.9 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin PLDc_2 PF13091.6 EGD89059.2 - 1.3e-16 60.7 0.0 3.2e-07 30.3 0.0 3.6 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 EGD89059.2 - 5.4e-14 51.7 0.6 1.6e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 EGD89059.2 - 0.096 11.9 0.1 0.51 9.5 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB DUF883 PF05957.13 EGD89059.2 - 0.36 11.5 1.6 0.83 10.3 0.6 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) GFA PF04828.14 EGD89060.2 - 5.5e-09 36.3 0.0 7.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cyanate_lyase PF02560.14 EGD89061.1 - 7.7e-33 112.2 0.0 1.6e-32 111.1 0.0 1.5 2 0 0 2 2 2 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 EGD89061.1 - 0.00016 21.9 0.0 0.00026 21.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EGD89061.1 - 0.0011 19.3 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 EGD89061.1 - 0.026 14.6 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r1_1 PF03979.14 EGD89061.1 - 0.081 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Myb_DNA-binding PF00249.31 EGD89061.1 - 0.2 11.9 0.0 42 4.4 0.0 3.1 3 0 0 3 3 3 0 Myb-like DNA-binding domain zf-C2H2_4 PF13894.6 EGD89062.1 - 1.5e-11 44.1 21.7 0.19 12.7 0.2 7.4 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.26 EGD89062.1 - 1.3e-06 28.5 23.9 0.12 12.9 0.0 6.1 7 0 0 7 7 6 3 Zinc finger, C2H2 type zf-met PF12874.7 EGD89062.1 - 6.8e-05 23.1 17.8 0.033 14.6 0.2 5.5 6 0 0 6 6 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGD89062.1 - 0.00036 20.7 0.6 0.055 13.8 0.0 5.5 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 EGD89062.1 - 0.0046 17.6 7.9 0.018 15.7 0.5 3.0 3 0 0 3 3 3 1 Zinc finger C2H2-type, 3 repeats Prok-RING_4 PF14447.6 EGD89062.1 - 0.05 13.5 3.1 3 7.8 1.7 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-CSL PF05207.13 EGD89062.1 - 0.084 12.6 7.6 0.24 11.1 0.1 2.7 2 1 0 2 2 2 0 CSL zinc finger zf-C2H2_2 PF12756.7 EGD89062.1 - 0.43 10.9 21.4 3.9 7.9 2.5 5.2 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 EGD89062.1 - 0.78 10.4 12.0 1.9 9.2 0.4 4.0 3 2 2 5 5 5 0 FOXP coiled-coil domain zf-C3HC4_2 PF13923.6 EGD89062.1 - 1 9.3 8.7 4.4 7.2 0.9 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_9 PF16293.5 EGD89062.1 - 1.7 8.5 9.7 7.1 6.6 0.7 4.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 EGD89062.1 - 2.7 8.5 7.2 11 6.6 0.3 3.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Zn-ribbon_8 PF09723.10 EGD89062.1 - 3.4 7.9 11.1 0.7 10.1 1.1 3.6 2 1 1 3 3 3 0 Zinc ribbon domain DZR PF12773.7 EGD89062.1 - 6 7.0 11.4 11 6.1 3.4 3.2 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 EGD89062.1 - 7 6.7 10.2 23 5.0 1.4 3.9 3 1 0 3 3 3 0 zinc-ribbon domain zf-C2H2_8 PF15909.5 EGD89062.1 - 9.1 6.7 10.2 1.2 9.5 1.7 2.8 2 1 1 3 3 3 0 C2H2-type zinc ribbon MFS_1 PF07690.16 EGD89065.1 - 7.5e-38 130.3 52.6 7.7e-37 127.0 49.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGD89065.1 - 0.65 8.8 32.2 0.0073 15.2 15.5 2.3 2 0 0 2 2 2 0 MFS_1 like family FAD_binding_3 PF01494.19 EGD89066.1 - 1.6e-12 47.3 0.0 0.0036 16.6 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 EGD89066.1 - 3.5e-05 23.6 0.0 0.00015 21.5 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGD89066.1 - 0.00023 21.3 0.0 0.00056 20.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGD89066.1 - 0.00046 19.5 0.0 0.00087 18.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGD89066.1 - 0.00048 19.6 0.1 0.0045 16.4 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EGD89066.1 - 0.00088 18.5 0.0 0.0021 17.2 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGD89066.1 - 0.0018 17.1 0.0 0.004 15.9 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EGD89066.1 - 0.0061 17.1 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EGD89066.1 - 0.039 13.8 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EGD89066.1 - 0.056 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.10 EGD89066.1 - 0.17 10.9 0.0 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase DNA_pol_B PF00136.21 EGD89067.2 - 1.1e-146 489.2 2.8 1.4e-146 488.8 2.8 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGD89067.2 - 7.5e-57 193.0 0.1 1.6e-56 191.9 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGD89067.2 - 1.4e-19 70.3 3.1 3.3e-19 69.1 3.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 EGD89067.2 - 0.00028 20.9 0.2 0.0016 18.4 0.2 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 EGD89067.2 - 0.0062 16.2 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 EGD89067.2 - 0.0097 15.8 6.7 0.054 13.4 1.0 2.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_pol_B_2 PF03175.13 EGD89067.2 - 0.017 14.0 1.6 0.02 13.8 0.0 1.8 2 1 0 2 2 2 0 DNA polymerase type B, organellar and viral ETC_C1_NDUFA5 PF04716.14 EGD89067.2 - 0.051 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 ETC complex I subunit conserved region Fungal_trans_2 PF11951.8 EGD89068.1 - 4.8e-11 42.1 1.4 2.4e-10 39.8 0.5 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD89068.1 - 6.8e-08 32.5 9.9 1.2e-07 31.7 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EGD89069.1 - 1.2e-31 110.0 0.0 4.8e-17 62.2 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD89069.1 - 2.9e-12 46.4 0.0 1.3e-05 24.6 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase IBV_3C PF03620.13 EGD89071.1 - 0.034 14.6 0.1 0.093 13.2 0.0 1.8 2 0 0 2 2 2 0 IBV 3C protein Glyco_hydro_47 PF01532.20 EGD89072.2 - 2.6e-128 428.8 0.0 3e-128 428.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TAtT PF16811.5 EGD89072.2 - 0.095 12.0 0.1 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 TRAP transporter T-component LIP PF03583.14 EGD89073.1 - 5.8e-80 268.7 0.0 7.6e-80 268.3 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Syja_N PF02383.18 EGD89074.1 - 1.4e-77 261.2 0.0 2.4e-77 260.4 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Tti2 PF10521.9 EGD89075.1 - 2.8e-90 302.7 3.3 5.6e-90 301.7 2.2 1.8 2 0 0 2 2 2 1 Tti2 family PolyA_pol PF01743.20 EGD89076.2 - 2.4e-24 86.1 0.2 8.2e-24 84.4 0.2 1.8 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EGD89076.2 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A TRAPPC-Trs85 PF12739.7 EGD89077.1 - 1.6e-108 363.3 0.0 1e-106 357.4 0.0 2.1 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DNase_NucA_NucB PF14040.6 EGD89078.1 - 0.033 14.5 0.0 0.046 14.1 0.0 1.2 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB Snf7 PF03357.21 EGD89080.1 - 9.3e-18 64.4 13.4 9.3e-18 64.4 13.4 2.1 1 1 1 2 2 2 1 Snf7 DUF948 PF06103.11 EGD89080.1 - 0.67 10.3 11.0 0.97 9.7 1.9 3.6 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.20 EGD89080.1 - 2.1 8.3 15.4 3.7 7.5 0.3 2.9 2 1 0 2 2 2 0 Prefoldin subunit MCU PF04678.13 EGD89080.1 - 3.4 7.8 7.2 1.1 9.4 0.5 2.4 1 1 1 2 2 2 0 Mitochondrial calcium uniporter YabA PF06156.13 EGD89080.1 - 3.8 8.2 9.6 3.2 8.5 1.9 2.6 2 0 0 2 2 2 0 Initiation control protein YabA DUF16 PF01519.16 EGD89080.1 - 3.9 8.0 12.7 0.084 13.4 1.2 3.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 FKBP_N PF01346.18 EGD89080.1 - 5.7 8.0 7.8 4.8 8.2 4.0 2.7 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase V_ATPase_I PF01496.19 EGD89080.1 - 8.1 4.2 9.9 4 5.2 5.3 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family zf-C3HC4_2 PF13923.6 EGD89081.1 - 3.1e-10 39.7 22.2 1e-09 38.0 15.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGD89081.1 - 3.8e-07 29.8 13.4 3.8e-07 29.8 13.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EGD89081.1 - 9.7e-07 28.6 7.7 9.7e-07 28.6 7.7 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 EGD89081.1 - 2.4e-06 27.3 17.0 2.4e-06 27.3 17.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGD89081.1 - 1.2e-05 25.2 16.4 1.2e-05 25.2 16.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGD89081.1 - 2e-05 24.8 22.1 4.1e-05 23.8 17.0 2.3 2 0 0 2 2 2 1 Ring finger domain SAP PF02037.27 EGD89081.1 - 3e-05 23.7 0.0 5.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-RING_UBOX PF13445.6 EGD89081.1 - 0.00018 21.5 22.8 0.00018 21.5 17.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGD89081.1 - 0.00036 20.3 17.1 0.069 13.0 15.1 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGD89081.1 - 0.00043 20.4 20.3 0.00073 19.6 17.0 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.15 EGD89081.1 - 0.019 15.2 0.0 0.069 13.3 0.0 2.0 2 0 0 2 2 1 0 U-box domain Mob_synth_C PF06463.13 EGD89081.1 - 0.037 14.0 5.5 0.077 12.9 5.5 1.5 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C Rad50_zn_hook PF04423.14 EGD89081.1 - 0.18 11.7 4.1 6.3 6.7 1.4 2.9 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 EGD89081.1 - 0.2 11.7 5.2 0.53 10.4 5.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGD89081.1 - 0.38 11.1 16.6 0.068 13.5 11.9 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-WRNIP1_ubi PF18279.1 EGD89081.1 - 1.8 9.4 5.1 3.7 8.4 0.2 2.9 3 0 0 3 3 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_10 PF16685.5 EGD89081.1 - 4.2 7.6 13.5 0.33 11.1 8.1 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 CDC27 PF09507.10 EGD89082.2 - 1.2e-89 301.7 32.8 1.4e-89 301.5 32.8 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Glyco_hydro_125 PF06824.11 EGD89083.2 - 1.4e-179 597.3 0.0 1.6e-179 597.1 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) RRM_1 PF00076.22 EGD89084.1 - 0.0023 17.7 0.0 1.2 9.0 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NMD3 PF04981.13 EGD89085.1 - 8.4e-80 267.7 4.1 1.5e-79 266.9 4.1 1.4 1 0 0 1 1 1 1 NMD3 family HypA PF01155.19 EGD89085.1 - 0.47 10.5 9.6 2.1 8.4 1.3 3.1 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rhodanese_C PF12368.8 EGD89085.1 - 9.5 6.7 9.5 5.2 7.5 6.3 2.0 2 0 0 2 2 2 0 Rhodanase C-terminal RsfS PF02410.15 EGD89086.1 - 3.5e-11 43.4 0.0 8.2e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Pex2_Pex12 PF04757.14 EGD89087.2 - 1.3e-29 103.4 0.3 1.7e-29 103.0 0.3 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EGD89087.2 - 1.5e-06 28.2 2.4 2.7e-06 27.4 2.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGD89087.2 - 0.00018 21.3 1.8 0.00038 20.2 1.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGD89087.2 - 0.00078 19.7 1.4 0.0017 18.6 1.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGD89087.2 - 0.00093 19.0 2.3 0.00096 19.0 1.3 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGD89087.2 - 0.0023 17.7 1.6 0.0046 16.8 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD89087.2 - 0.0035 17.4 1.9 0.0035 17.4 1.9 1.9 2 0 0 2 2 2 1 RING-type zinc-finger Mito_carr PF00153.27 EGD89088.1 - 6.2e-60 199.2 4.0 1.7e-21 75.9 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGD89088.1 - 0.018 14.2 0.0 2.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease WSD PF15613.6 EGD89089.2 - 3.5e-23 81.9 0.5 3.5e-23 81.9 0.5 3.3 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EGD89089.2 - 2.5e-17 62.9 1.5 4.4e-17 62.1 1.5 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EGD89089.2 - 4.1e-10 38.9 0.0 1e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 CtIP_N PF10482.9 EGD89089.2 - 5.6 7.0 13.4 3.5 7.7 0.9 3.5 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Lectin_leg-like PF03388.13 EGD89091.2 - 1.1e-24 87.1 0.0 1.6e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Dynamitin PF04912.14 EGD89091.2 - 0.0059 16.0 1.6 0.0079 15.6 1.6 1.1 1 0 0 1 1 1 1 Dynamitin TMF_TATA_bd PF12325.8 EGD89091.2 - 0.009 16.2 1.4 0.016 15.4 1.4 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding ALMT PF11744.8 EGD89091.2 - 0.017 14.0 0.5 0.024 13.5 0.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4349 PF14257.6 EGD89091.2 - 0.029 13.8 1.3 0.062 12.7 1.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) WXG100 PF06013.12 EGD89091.2 - 0.074 13.3 0.2 0.8 10.0 0.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Spore_YpjB PF09577.10 EGD89091.2 - 0.11 12.2 1.2 0.57 9.9 0.2 2.1 1 1 1 2 2 2 0 Sporulation protein YpjB (SpoYpjB) KxDL PF10241.9 EGD89091.2 - 0.2 12.0 1.3 0.39 11.0 1.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein FUSC PF04632.12 EGD89091.2 - 0.29 9.6 1.1 0.4 9.2 1.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spectrin PF00435.21 EGD89091.2 - 0.45 11.0 3.0 2.4 8.7 0.2 2.2 1 1 1 2 2 2 0 Spectrin repeat DUF5385 PF17359.2 EGD89091.2 - 0.67 9.5 3.3 0.63 9.6 0.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Fib_alpha PF08702.10 EGD89091.2 - 1.2 9.4 4.2 2.3 8.4 4.2 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Exo_endo_phos PF03372.23 EGD89095.2 - 1.2e-07 31.5 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.12 EGD89096.1 - 7.2e-64 215.8 0.0 1.6e-62 211.4 0.0 2.3 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 INO80_Ies4 PF08193.11 EGD89096.1 - 0.00014 22.0 2.6 0.00014 22.0 2.6 3.7 4 1 1 5 5 5 1 INO80 complex subunit Ies4 HEAT_2 PF13646.6 EGD89097.1 - 2.8e-09 37.3 2.8 8e-08 32.6 0.7 3.6 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 EGD89097.1 - 8e-07 28.8 6.0 0.11 12.8 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EGD89097.1 - 7.7e-05 22.8 1.0 0.0074 16.4 0.0 4.3 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGD89097.1 - 0.029 13.9 0.0 5.3 6.5 0.0 3.0 1 1 1 2 2 2 0 CLASP N terminal DUF3734 PF12536.8 EGD89097.1 - 0.076 13.4 0.2 1.3 9.4 0.1 3.1 2 0 0 2 2 2 0 Patatin phospholipase Arena_ncap_C PF17290.2 EGD89097.1 - 0.11 11.8 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain HEAT_EZ PF13513.6 EGD89097.1 - 0.63 10.6 15.5 0.2 12.2 0.2 5.5 7 0 0 7 7 7 0 HEAT-like repeat MFS_1 PF07690.16 EGD89098.2 - 2.2e-08 33.4 10.2 2.2e-08 33.4 10.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PAP2_C PF14360.6 EGD89098.2 - 6 7.5 8.0 0.43 11.2 0.5 2.7 3 0 0 3 3 3 0 PAP2 superfamily C-terminal PHD PF00628.29 EGD89100.1 - 5.3e-09 35.8 8.0 5.3e-09 35.8 8.0 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 EGD89100.1 - 1.4e-08 34.9 1.8 1.4e-08 34.9 1.8 3.4 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 EGD89100.1 - 1e-06 28.9 1.3 1e-06 28.9 1.3 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGD89100.1 - 7.9e-06 25.6 1.9 7.9e-06 25.6 1.9 3.0 3 1 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGD89100.1 - 1.2e-05 25.1 0.5 1.2e-05 25.1 0.5 2.6 3 1 0 3 3 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGD89100.1 - 1.5e-05 24.7 3.6 1.5e-05 24.7 3.6 2.9 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 EGD89100.1 - 3.7e-05 23.2 3.9 9e-05 22.0 3.9 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_4 PF14447.6 EGD89100.1 - 5e-05 23.1 1.5 5e-05 23.1 1.5 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGD89100.1 - 7.9e-05 22.4 1.1 7.9e-05 22.4 1.1 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGD89100.1 - 0.00044 20.2 0.3 0.00044 20.2 0.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGD89100.1 - 0.0042 17.1 2.4 0.0042 17.1 2.4 3.8 2 2 1 3 3 2 1 RING-type zinc-finger zinc_ribbon_16 PF17034.5 EGD89100.1 - 0.033 14.4 0.3 0.07 13.3 0.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family DUF1644 PF07800.12 EGD89100.1 - 0.19 11.8 5.9 0.41 10.7 2.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) zf-PHD-like PF15446.6 EGD89100.1 - 0.52 9.9 7.9 0.043 13.4 2.2 2.1 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-RING_4 PF14570.6 EGD89100.1 - 1.1 9.1 6.5 0.13 12.0 0.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_10 PF10058.9 EGD89100.1 - 5.4 6.8 7.7 1.3 8.8 3.9 1.9 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_ribbon_17 PF17120.5 EGD89100.1 - 8.6 6.1 10.3 0.39 10.4 1.5 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Ribosomal_L37ae PF01780.19 EGD89101.1 - 2.7e-40 136.3 11.5 3e-40 136.2 11.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EGD89101.1 - 0.00028 21.0 1.5 0.00038 20.5 1.5 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 EGD89101.1 - 0.0031 17.4 2.8 0.0052 16.7 2.8 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.15 EGD89101.1 - 0.026 14.5 4.6 1.1 9.4 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger DUF1451 PF07295.11 EGD89101.1 - 0.036 14.1 0.4 0.051 13.6 0.4 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Abhydrolase_1 PF00561.20 EGD89103.2 - 0.0013 18.4 0.0 0.0015 18.2 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD89103.2 - 0.013 16.1 0.1 0.015 15.9 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pinin_SDK_memA PF04696.13 EGD89104.1 - 4.4e-32 110.9 8.5 4.4e-32 110.9 8.5 2.4 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region DUF3449 PF11931.8 EGD89104.1 - 1.4 8.7 6.9 2.1 8.1 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) 2OG-FeII_Oxy PF03171.20 EGD89105.2 - 1.3e-20 73.8 0.0 2.7e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2141 PF09912.9 EGD89105.2 - 0.00097 19.0 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2141) Myb_DNA-binding PF00249.31 EGD89106.1 - 2.3e-30 104.5 16.5 2.9e-11 43.4 0.6 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGD89106.1 - 5.5e-29 100.2 11.3 1.5e-13 50.8 1.6 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 EGD89106.1 - 0.0016 18.7 10.5 0.29 11.5 0.7 3.9 3 1 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 EGD89106.1 - 0.0063 16.6 4.9 2.1 8.5 0.3 3.4 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EGD89106.1 - 0.014 15.4 0.0 0.21 11.6 0.0 2.5 1 1 2 3 3 3 0 SLIDE MFS_1 PF07690.16 EGD89107.1 - 1.7e-38 132.5 47.1 5.4e-38 130.8 46.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGD89107.1 - 1.6e-11 43.4 9.7 2.4e-11 42.8 9.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4728 PF15860.5 EGD89107.1 - 6 7.6 9.9 1.2 9.9 0.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4728) p450 PF00067.22 EGD89108.2 - 1.4e-51 175.7 0.0 1.7e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 EGD89109.2 - 4.6e-72 242.6 0.0 7.5e-72 241.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 EGD89109.2 - 1.7e-34 117.5 1.2 3.7e-34 116.5 0.4 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 EGD89109.2 - 7.5e-33 113.1 0.0 1.5e-32 112.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EGD89109.2 - 4e-23 82.4 0.0 7.2e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EGD89109.2 - 1e-20 74.0 0.0 2.2e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 EGD89109.2 - 4.3e-14 53.0 0.0 1.1e-13 51.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD89109.2 - 5.8e-11 42.9 0.0 1.7e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD89109.2 - 6.5e-10 39.0 0.0 1.7e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGD89109.2 - 8.9e-10 38.8 0.3 2.5e-09 37.3 0.3 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 EGD89109.2 - 2.8e-09 37.5 0.0 8.4e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD89109.2 - 6e-09 36.0 0.0 3.1e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.21 EGD89109.2 - 4.3e-07 29.7 0.0 8.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 EGD89109.2 - 2.4e-06 27.1 0.1 3.2e-05 23.4 0.2 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 EGD89109.2 - 5.4e-05 22.6 0.0 0.00021 20.7 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family KAsynt_C_assoc PF16197.5 EGD89109.2 - 0.0013 19.2 0.0 0.003 18.0 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Polysacc_synt_2 PF02719.15 EGD89109.2 - 0.0026 16.9 0.0 0.018 14.2 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EGD89109.2 - 0.022 14.7 0.0 0.063 13.2 0.0 1.8 1 0 0 1 1 1 0 KR domain DXP_reductoisom PF02670.16 EGD89109.2 - 0.027 15.2 0.1 0.063 14.0 0.1 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Methyltransf_32 PF13679.6 EGD89109.2 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 EGD89109.2 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) DNA_pol3_chi PF04364.13 EGD89109.2 - 0.23 11.6 0.4 8.9 6.5 0.2 3.2 3 0 0 3 3 3 0 DNA polymerase III chi subunit, HolC Pkinase PF00069.25 EGD89110.1 - 1.2e-22 80.6 0.0 1.6e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD89110.1 - 6.2e-10 38.8 0.0 7.2e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD89110.1 - 3.8e-06 25.9 0.1 5.5e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGD89110.1 - 8.2e-05 22.6 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGD89110.1 - 0.0072 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 EGD89110.1 - 0.093 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 EGD89110.1 - 0.097 12.3 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Cofilin_ADF PF00241.20 EGD89112.1 - 4e-30 104.1 0.0 1.3e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.27 EGD89113.2 - 1.3e-44 150.0 0.7 1.4e-22 79.4 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial carrier protein CAF1 PF04857.20 EGD89114.1 - 4.3e-83 279.1 0.0 5.7e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease YTV PF07639.11 EGD89114.1 - 0.071 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 YTV HDA2-3 PF11496.8 EGD89114.1 - 0.088 12.0 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 TFIIF_alpha PF05793.12 EGD89115.2 - 0.00092 17.9 15.5 0.0011 17.7 15.5 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Suf PF05843.14 EGD89115.2 - 0.05 13.6 7.7 0.06 13.3 7.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SRP-alpha_N PF04086.13 EGD89115.2 - 0.075 12.9 19.0 0.1 12.5 19.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 EGD89115.2 - 0.083 11.2 13.8 0.11 10.8 13.8 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM220 PF15487.6 EGD89115.2 - 0.26 10.9 11.0 0.35 10.5 11.0 1.2 1 0 0 1 1 1 0 FAM220 family SLC12 PF03522.15 EGD89115.2 - 1 8.3 9.6 1.2 8.1 9.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Folliculin PF11704.8 EGD89115.2 - 1.1 9.0 8.4 1.8 8.4 8.4 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport GREB1 PF15782.5 EGD89115.2 - 2.2 5.3 8.4 2.5 5.1 8.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAPS PF04499.15 EGD89115.2 - 2.8 6.6 11.4 3.6 6.3 11.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 EGD89115.2 - 2.9 7.6 20.7 5.2 6.8 20.7 1.5 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 XRN_M PF17846.1 EGD89115.2 - 2.9 6.7 9.9 3.6 6.4 9.9 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Ndc1_Nup PF09531.10 EGD89115.2 - 3 6.4 8.4 3.7 6.1 8.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Borrelia_P83 PF05262.11 EGD89115.2 - 3.1 6.2 18.5 3.8 5.9 18.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein BSMAP PF12280.8 EGD89115.2 - 3.5 7.8 7.5 20 5.3 4.8 2.1 2 0 0 2 2 2 0 Brain specific membrane anchored protein ALMT PF11744.8 EGD89115.2 - 3.9 6.2 9.5 4.8 5.9 9.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM178 PF14816.6 EGD89115.2 - 4.1 6.3 14.1 7.7 5.4 14.1 1.4 1 0 0 1 1 1 0 Family of unknown function, FAM178 Rrn6 PF10214.9 EGD89115.2 - 4.9 5.5 14.9 6 5.2 14.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NARP1 PF12569.8 EGD89115.2 - 7 5.4 16.3 8.4 5.2 16.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CobT PF06213.12 EGD89115.2 - 7.2 5.9 19.6 10 5.4 19.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paramyxo_ncap PF00973.19 EGD89115.2 - 7.4 5.4 10.6 9.4 5.0 10.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1682 PF07946.14 EGD89115.2 - 8 5.6 17.9 11 5.0 17.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) vATP-synt_E PF01991.18 EGD89115.2 - 8.2 5.8 19.5 15 4.9 19.5 1.4 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit MRP-L46 PF11788.8 EGD89116.1 - 7.3e-39 133.2 0.2 1.1e-38 132.6 0.2 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Cript PF10235.9 EGD89117.1 - 1.3e-24 86.6 9.8 1.3e-24 86.6 9.8 1.9 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 EGD89117.1 - 0.0043 17.0 14.8 0.46 10.5 10.1 2.9 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 EGD89117.1 - 0.03 15.1 12.6 0.079 13.7 9.3 2.7 2 1 0 2 2 2 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 EGD89117.1 - 0.31 10.8 8.7 9.5 6.1 0.8 3.3 2 1 2 4 4 4 0 zinc-ribbon domain CEBP_ZZ PF16366.5 EGD89117.1 - 0.35 11.1 8.1 0.23 11.7 4.7 2.0 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain LIM PF00412.22 EGD89117.1 - 1.6 9.1 11.1 2.2 8.6 0.1 3.5 3 1 0 3 3 3 0 LIM domain DUF1272 PF06906.11 EGD89117.1 - 2.5 8.3 8.7 0.75 9.9 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DUF2039 PF10217.9 EGD89117.1 - 4 7.8 17.3 2.4 8.5 11.3 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF1349 PF07081.11 EGD89119.1 - 1.7e-22 80.0 0.0 2.9e-22 79.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) AMPK1_CBM PF16561.5 EGD89121.1 - 3.4e-07 30.4 0.1 8.8e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase JIP_LZII PF16471.5 EGD89122.1 - 0.14 12.4 0.7 0.25 11.5 0.1 1.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II NOC3p PF07540.11 EGD89123.1 - 2.1e-29 101.8 0.3 1.6e-28 99.0 0.3 2.5 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 EGD89123.1 - 5.9e-26 91.5 1.4 2.5e-24 86.2 0.0 3.0 2 1 0 2 2 2 1 CBF/Mak21 family Adaptin_N PF01602.20 EGD89123.1 - 0.028 13.0 1.3 4.2 5.8 0.0 2.8 3 0 0 3 3 3 0 Adaptin N terminal region Orbi_VP1 PF05788.12 EGD89123.1 - 0.038 11.6 0.2 0.06 10.9 0.2 1.2 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) UPF0113_N PF17833.1 EGD89124.1 - 4.7e-25 88.0 0.0 6.3e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EGD89124.1 - 9.7e-24 83.4 0.0 1.4e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 EGD89124.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 PUA domain Cullin_binding PF03556.15 EGD89125.2 - 2.8e-31 108.5 3.6 4.2e-31 107.9 3.6 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 EGD89125.2 - 1.2e-14 53.8 0.7 2.7e-14 52.7 0.0 2.0 3 0 0 3 3 3 1 UBA-like domain TAP_C PF03943.13 EGD89125.2 - 0.0036 16.9 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain CUE PF02845.16 EGD89125.2 - 0.1 12.3 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 CUE domain SprT-like PF10263.9 EGD89126.2 - 6.9e-10 38.8 0.0 1.8e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 SprT-like family Mpv17_PMP22 PF04117.12 EGD89127.1 - 1.8e-13 50.5 1.7 1.1e-11 44.7 0.7 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family CKAP2_C PF15297.6 EGD89127.1 - 0.094 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus IBR PF01485.21 EGD89128.2 - 2.1 8.6 6.4 0.55 10.5 0.4 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain PEX11 PF05648.14 EGD89129.1 - 8.1e-17 61.4 1.6 4.2e-14 52.6 0.3 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) PsiF_repeat PF07769.14 EGD89131.1 - 0.064 13.1 0.1 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 psiF repeat AAA PF00004.29 EGD89134.1 - 1e-96 320.4 0.0 2e-47 160.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD89134.1 - 2.5e-24 84.8 5.5 6.7e-13 48.2 0.3 3.3 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EGD89134.1 - 1e-18 67.3 1.4 2.3e-18 66.1 0.6 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 EGD89134.1 - 3e-14 53.5 0.0 1.1e-07 32.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGD89134.1 - 8.9e-14 51.5 0.0 1.4e-05 24.9 0.0 3.4 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGD89134.1 - 2.6e-12 47.1 0.0 2.3e-05 24.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EGD89134.1 - 3.7e-11 43.7 0.0 0.00014 22.2 0.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EGD89134.1 - 3.4e-10 40.1 0.6 4.5e-05 23.5 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGD89134.1 - 6.4e-09 36.2 0.5 0.053 13.8 0.0 4.1 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 EGD89134.1 - 7.4e-09 35.3 0.1 0.0015 17.8 0.0 2.6 2 1 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 EGD89134.1 - 5e-08 32.6 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 EGD89134.1 - 3.1e-07 30.3 0.0 0.02 14.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGD89134.1 - 4.4e-07 29.5 0.4 0.033 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGD89134.1 - 1.1e-06 29.2 0.0 0.055 14.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain ATPase PF06745.13 EGD89134.1 - 1.1e-06 28.2 0.4 0.64 9.3 0.0 3.5 3 0 0 3 3 3 2 KaiC Vps4_C PF09336.10 EGD89134.1 - 1.7e-06 27.9 0.4 1.7e-05 24.7 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 EGD89134.1 - 1.9e-06 28.2 0.0 0.028 14.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EGD89134.1 - 2.5e-06 27.5 0.0 0.023 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGD89134.1 - 4.4e-06 26.4 6.5 0.43 10.1 0.1 4.9 3 2 1 5 5 5 2 AAA domain AAA_7 PF12775.7 EGD89134.1 - 7.1e-06 25.6 0.1 0.035 13.6 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 EGD89134.1 - 3e-05 24.3 0.0 0.3 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 EGD89134.1 - 3.7e-05 23.0 0.0 0.0086 15.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EGD89134.1 - 4.8e-05 23.9 0.0 0.26 11.8 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 EGD89134.1 - 7.3e-05 22.5 0.1 0.75 9.5 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.16 EGD89134.1 - 8.3e-05 22.1 0.4 0.35 10.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.6 EGD89134.1 - 8.5e-05 22.4 0.0 0.66 9.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 EGD89134.1 - 0.00011 21.5 0.1 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 EGD89134.1 - 0.00026 20.9 0.0 0.69 9.7 0.0 2.8 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_11 PF13086.6 EGD89134.1 - 0.00031 20.6 0.0 0.41 10.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain ResIII PF04851.15 EGD89134.1 - 0.00041 20.4 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 EGD89134.1 - 0.00045 20.6 0.0 0.88 10.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EGD89134.1 - 0.0006 19.8 0.0 0.62 10.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EGD89134.1 - 0.00072 19.4 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EGD89134.1 - 0.0018 17.6 0.0 0.84 8.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EGD89134.1 - 0.0039 16.9 0.6 2.6 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EGD89134.1 - 0.0044 17.0 0.0 11 5.8 0.0 3.6 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGD89134.1 - 0.0054 17.1 0.7 6.9 7.0 0.0 3.5 3 1 0 4 4 2 0 AAA domain NACHT PF05729.12 EGD89134.1 - 0.0071 16.3 0.1 1.6 8.6 0.0 3.0 3 0 0 3 3 3 1 NACHT domain Viral_helicase1 PF01443.18 EGD89134.1 - 0.008 15.9 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UFD1 PF03152.14 EGD89134.1 - 0.0086 15.6 0.0 0.069 12.6 0.0 2.1 1 1 1 2 2 2 1 Ubiquitin fusion degradation protein UFD1 KAP_NTPase PF07693.14 EGD89134.1 - 0.019 14.2 0.0 0.73 9.0 0.0 2.6 2 1 0 2 2 2 0 KAP family P-loop domain Sigma54_activ_2 PF14532.6 EGD89134.1 - 0.022 14.9 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGD89134.1 - 0.026 13.8 1.5 6.2 6.0 0.0 3.1 4 0 0 4 4 3 0 Zeta toxin NB-ARC PF00931.22 EGD89134.1 - 0.026 13.7 0.0 1.9 7.6 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain IPT PF01745.16 EGD89134.1 - 0.029 13.8 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase eIF-1a PF01176.19 EGD89134.1 - 0.03 14.1 0.8 1.1 9.2 0.7 2.8 2 1 0 2 2 1 0 Translation initiation factor 1A / IF-1 NTPase_1 PF03266.15 EGD89134.1 - 0.052 13.5 3.0 3.7 7.4 0.0 4.1 5 0 0 5 5 4 0 NTPase T2SSE PF00437.20 EGD89134.1 - 0.082 12.0 0.0 3.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 EGD89134.1 - 0.084 12.6 0.2 18 5.0 0.0 3.1 3 0 0 3 3 2 0 Cytidylate kinase LXG PF04740.12 EGD89134.1 - 0.089 12.5 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily AAA_6 PF12774.7 EGD89134.1 - 0.11 11.4 0.1 11 4.9 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Zot PF05707.12 EGD89134.1 - 0.14 11.8 0.0 7 6.2 0.0 3.0 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) EnY2 PF10163.9 EGD89135.1 - 5.9e-07 29.8 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Transcription factor e(y)2 SAM_2 PF07647.17 EGD89136.1 - 3.1e-15 56.0 0.0 5.1e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EGD89136.1 - 5e-12 46.3 0.1 1.3e-11 45.0 0.0 1.7 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 EGD89136.1 - 7.8e-12 45.5 0.0 1.2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 EGD89136.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Nha1_C PF08619.10 EGD89137.1 - 1.2e-80 272.1 17.7 1.5e-80 271.7 17.7 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 EGD89137.1 - 1.3e-73 248.0 20.5 1.5e-73 247.8 20.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 EGD89137.1 - 0.047 13.8 0.3 0.047 13.8 0.3 2.5 3 0 0 3 3 3 0 YrhC-like protein PX PF00787.24 EGD89138.1 - 6.8e-17 61.5 0.2 1.4e-16 60.4 0.2 1.5 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.6 EGD89138.1 - 3.3 7.8 5.2 1.3 9.1 0.2 2.8 4 0 0 4 4 4 0 Prefoldin subunit Tmemb_cc2 PF10267.9 EGD89138.1 - 5.5 6.0 9.9 0.049 12.8 0.7 2.1 3 0 0 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein AAA PF00004.29 EGD89139.1 - 3.5e-09 37.2 0.3 2.7e-08 34.3 0.3 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGD89139.1 - 2.4e-07 30.9 0.0 0.00079 19.4 0.0 3.4 3 0 0 3 3 3 2 Rad17 P-loop domain RuvB_N PF05496.12 EGD89139.1 - 0.0074 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGD89139.1 - 0.0075 16.7 0.0 0.02 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGD89139.1 - 0.044 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGD89139.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGD89139.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 EGD89139.1 - 0.15 12.3 0.1 1.8 8.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain Utp8 PF10395.9 EGD89140.1 - 2.8e-07 29.5 1.6 1.3e-05 24.0 2.1 2.8 2 1 0 2 2 2 2 Utp8 family Fungal_trans PF04082.18 EGD89141.2 - 2.6e-21 75.9 0.5 4.5e-21 75.1 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EGD89141.2 - 2.5e-09 37.1 14.0 7.2e-05 23.0 2.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGD89141.2 - 1.6e-06 28.3 12.4 3.2e-06 27.3 6.6 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGD89141.2 - 0.00032 21.3 13.1 0.041 14.7 2.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger CAF1C_H4-bd PF12265.8 EGD89144.2 - 5e-16 58.7 0.1 3e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGD89144.2 - 3.5e-14 53.0 7.9 2.2e-06 28.3 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD89144.2 - 7.1e-08 32.6 1.6 0.00081 19.6 0.3 3.2 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD89144.2 - 0.02 13.5 2.6 0.11 11.1 0.2 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 UL41A PF17591.2 EGD89144.2 - 0.16 12.1 0.0 0.56 10.3 0.0 1.9 1 0 0 1 1 1 0 Herpesvirus UL41A Vpu PF00558.19 EGD89144.2 - 0.19 11.6 1.5 0.35 10.7 1.5 1.4 1 0 0 1 1 1 0 Vpu protein Ras PF00071.22 EGD89145.1 - 1.3e-30 106.2 0.2 1.3e-30 106.2 0.2 1.4 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGD89145.1 - 3.4e-23 82.1 0.1 3.4e-23 82.1 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD89145.1 - 2.2e-06 27.3 0.1 3.8e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGD89145.1 - 0.00052 19.4 0.2 0.00052 19.4 0.2 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EGD89145.1 - 0.0019 17.1 0.1 1.1 8.0 0.0 2.3 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) CrgA PF06781.12 EGD89145.1 - 0.043 13.9 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Cell division protein CrgA TFIIA PF03153.13 EGD89145.1 - 0.19 11.7 32.0 0.26 11.2 32.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAP PF07174.11 EGD89145.1 - 1.6 8.2 16.3 2.7 7.4 16.3 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Transglut_core PF01841.19 EGD89146.1 - 3.6e-13 49.9 0.0 6.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sugar_tr PF00083.24 EGD89148.1 - 8.6e-99 331.4 12.1 1.3e-98 330.8 12.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGD89148.1 - 4.5e-20 71.9 34.2 1.9e-19 69.8 18.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 EGD89148.1 - 8.9e-06 24.8 0.3 1.7e-05 24.0 0.3 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 EGD89148.1 - 0.00086 17.8 0.9 0.0017 16.9 0.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 EGD89148.1 - 0.05 13.9 1.7 0.32 11.2 1.7 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) DUF3487 PF11990.8 EGD89148.1 - 3 7.8 7.8 13 5.7 1.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) TRAM_LAG1_CLN8 PF03798.16 EGD89149.1 - 1.1e-33 116.6 17.8 1.8e-33 116.0 17.8 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EGD89149.1 - 1e-21 76.3 0.0 3e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein Asp-B-Hydro_N PF05279.11 EGD89150.2 - 3.7 7.5 28.6 4.8 7.2 28.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mitofilin PF09731.9 EGD89150.2 - 4.2 6.1 29.4 4.9 5.9 29.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SAPS PF04499.15 EGD89150.2 - 6.3 5.5 7.4 6.6 5.4 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TIP120 PF08623.10 EGD89151.2 - 2.7e-65 219.2 0.0 5e-64 215.1 0.0 2.6 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EGD89151.2 - 4e-09 36.0 3.0 0.12 12.7 0.0 7.1 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 EGD89151.2 - 7e-07 29.5 8.4 0.29 11.6 0.0 6.6 5 2 2 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 EGD89151.2 - 1.4e-05 25.5 6.6 2 9.0 0.0 8.9 9 1 1 10 10 10 1 HEAT-like repeat DUF3295 PF11702.8 EGD89151.2 - 0.013 14.8 0.2 0.022 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Arm PF00514.23 EGD89151.2 - 0.11 12.6 3.1 23 5.2 0.0 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 EGD89151.2 - 1.8 9.5 8.6 0.54 11.1 0.4 4.9 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat bZIP_2 PF07716.15 EGD89154.2 - 2.4e-08 33.9 14.2 2.4e-08 33.9 14.2 2.9 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.21 EGD89154.2 - 5.6e-06 26.4 17.9 5.6e-06 26.4 17.9 2.4 2 1 0 2 2 2 1 bZIP transcription factor SAP130_C PF16014.5 EGD89154.2 - 0.0051 16.0 6.5 0.0098 15.0 6.5 1.4 1 0 0 1 1 1 1 Histone deacetylase complex subunit SAP130 C-terminus bZIP_Maf PF03131.17 EGD89154.2 - 0.008 16.7 12.0 0.008 16.7 12.0 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor FPP PF05911.11 EGD89154.2 - 0.014 13.6 6.3 0.022 13.0 6.3 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DLIC PF05783.11 EGD89154.2 - 0.046 12.5 5.1 0.066 12.0 5.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Striatin PF08232.12 EGD89154.2 - 0.33 11.5 13.2 0.21 12.2 10.9 2.1 1 1 0 1 1 1 0 Striatin family KIAA1430 PF13879.6 EGD89154.2 - 1.7 9.5 13.4 3.2 8.5 10.3 2.9 3 1 1 4 4 4 0 KIAA1430 homologue ATF7IP_BD PF16788.5 EGD89154.2 - 5.8 7.0 12.3 9.6 6.2 12.3 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain FSA_C PF10479.9 EGD89154.2 - 9.7 4.2 7.6 15 3.6 7.6 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus BTRD1 PF17660.1 EGD89155.1 - 3.9e-73 241.1 6.8 1.1e-14 53.9 1.0 5.0 5 0 0 5 5 5 5 Bacterial tandem repeat domain 1 RXLR PF16810.5 EGD89155.1 - 0.018 15.5 0.1 0.046 14.1 0.1 1.7 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity DUF3884 PF13024.6 EGD89155.1 - 0.085 12.4 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) DUF3347 PF11827.8 EGD89156.1 - 8.7 6.5 8.7 14 5.8 4.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Amidase PF01425.21 EGD89157.1 - 1.7e-115 386.6 0.1 2.6e-115 386.0 0.1 1.2 1 0 0 1 1 1 1 Amidase DUF1539 PF07560.11 EGD89157.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Big_3_5 PF16640.5 EGD89157.1 - 2.2 8.5 5.7 3.6 7.8 1.8 2.4 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 3) Bystin PF05291.11 EGD89159.2 - 3.6e-89 298.9 0.0 4.1e-89 298.7 0.0 1.0 1 0 0 1 1 1 1 Bystin Actin PF00022.19 EGD89160.1 - 3.2e-21 75.4 0.0 1.2e-17 63.6 0.0 3.1 3 0 0 3 3 3 3 Actin CBFD_NFYB_HMF PF00808.23 EGD89161.1 - 1.6e-18 66.7 0.3 1.6e-18 66.7 0.3 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGD89161.1 - 0.00016 22.1 0.3 0.00046 20.6 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGD89161.1 - 0.026 14.6 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGD89161.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated YolD PF08863.10 EGD89161.1 - 0.19 11.8 4.4 0.11 12.5 2.3 1.7 2 0 0 2 2 2 0 YolD-like protein adh_short PF00106.25 EGD89162.1 - 1e-40 139.3 0.0 1.4e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD89162.1 - 7.9e-26 91.0 0.0 9.4e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD89162.1 - 1.7e-08 34.6 0.0 2.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGD89162.1 - 0.00015 21.7 0.1 0.00028 20.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 EGD89162.1 - 0.0002 21.6 0.0 0.00034 20.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 EGD89162.1 - 0.00044 19.8 0.0 0.0044 16.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EGD89162.1 - 0.03 13.9 0.1 0.056 13.0 0.1 1.5 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.19 EGD89162.1 - 0.049 12.6 0.0 0.087 11.8 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PALP PF00291.25 EGD89162.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme AA_permease_2 PF13520.6 EGD89163.1 - 3e-70 237.2 35.8 3.8e-70 236.9 35.8 1.1 1 0 0 1 1 1 1 Amino acid permease DAP10 PF07213.11 EGD89163.1 - 0.03 14.3 1.6 0.72 9.8 0.4 2.6 2 0 0 2 2 2 0 DAP10 membrane protein APH PF01636.23 EGD89164.1 - 1.4e-10 41.6 0.0 2.2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD89164.1 - 1.9e-05 24.4 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EGD89164.1 - 6.1e-05 22.5 0.0 0.065 12.6 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Fructosamin_kin PF03881.14 EGD89164.1 - 0.018 14.3 0.0 3.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Pkinase_Tyr PF07714.17 EGD89164.1 - 0.2 10.9 0.0 0.34 10.2 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase DUF1679 PF07914.11 EGD89164.1 - 0.21 10.4 0.0 1.2 8.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) APH PF01636.23 EGD89165.2 - 4.1e-15 56.4 0.0 1.6e-14 54.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGD89165.2 - 0.015 14.1 0.0 1 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DJ-1_PfpI PF01965.24 EGD89166.1 - 1.4e-20 73.7 0.0 2.2e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EGD89166.1 - 0.00018 21.3 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DAO PF01266.24 EGD89167.2 - 1.8e-22 80.4 0.0 2e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Peptidase_C12 PF01088.21 EGD89169.1 - 2e-48 164.9 0.0 2.5e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MBOAT_2 PF13813.6 EGD89172.2 - 9.2e-05 22.6 0.1 0.00017 21.7 0.1 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Abhydrolase_6 PF12697.7 EGD89173.1 - 1.6e-13 51.8 0.1 1.8e-13 51.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EGD89173.1 - 0.059 13.2 0.0 0.48 10.3 0.0 2.1 1 1 0 1 1 1 0 Serine hydrolase Abhydrolase_5 PF12695.7 EGD89173.1 - 0.18 11.6 0.2 0.69 9.7 0.2 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pyridoxal_deC PF00282.19 EGD89174.1 - 5.7e-103 344.5 0.0 6.7e-103 344.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EGD89174.1 - 0.00029 20.2 0.0 0.00081 18.8 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase TMEM51 PF15345.6 EGD89175.2 - 2.2e-05 24.5 0.7 3.5e-05 23.8 0.7 1.6 1 1 0 1 1 1 1 Transmembrane protein 51 GDC-P PF02347.16 EGD89176.1 - 1.1e-93 314.5 0.2 3.7e-81 273.2 0.1 2.6 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EGD89176.1 - 4e-07 29.6 0.1 7.2e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGD89176.1 - 0.0027 17.1 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family TraF_2 PF13729.6 EGD89176.1 - 0.1 11.9 0.2 0.2 11.0 0.2 1.4 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Aminotran_3 PF00202.21 EGD89176.1 - 0.16 10.6 0.0 0.31 9.6 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III F-box_4 PF15966.5 EGD89179.1 - 3.8e-07 30.0 0.1 8.9e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 EGD89179.1 - 1.6e-06 27.9 1.3 2.9e-06 27.1 0.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGD89179.1 - 6.6e-06 25.9 1.5 1.8e-05 24.5 0.5 2.2 2 0 0 2 2 2 1 F-box domain Amidohydro_1 PF01979.20 EGD89181.1 - 5.4e-72 243.0 0.0 6.3e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGD89181.1 - 3.3e-09 36.7 0.1 1.8e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EGD89181.1 - 0.00014 21.3 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Toxin_29 PF08116.11 EGD89181.1 - 0.035 14.1 0.3 0.1 12.6 0.3 1.8 1 0 0 1 1 1 0 PhTx neurotoxin family tRNA_int_end_N2 PF12928.7 EGD89181.1 - 0.051 13.8 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term Sulfatase PF00884.23 EGD89182.1 - 1.6e-58 198.5 0.1 2.3e-58 198.0 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 EGD89182.1 - 7.7e-21 73.7 0.1 4.9e-20 71.1 0.0 2.1 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 EGD89182.1 - 4.3e-08 33.1 0.0 6e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 EGD89182.1 - 0.032 14.5 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 EGD89182.1 - 0.037 14.8 0.0 0.099 13.4 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF229 PF02995.17 EGD89182.1 - 0.093 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Fungal_trans PF04082.18 EGD89183.1 - 8.4e-15 54.5 0.0 1.3e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD89183.1 - 2.9e-08 33.7 9.3 4.9e-08 33.0 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EGD89185.1 - 1.6e-41 142.4 54.7 1.6e-40 139.1 54.7 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3377 PF11857.8 EGD89185.1 - 0.042 13.8 0.1 0.042 13.8 0.1 3.2 4 1 1 5 5 5 0 Domain of unknown function (DUF3377) Strabismus PF06638.11 EGD89185.1 - 0.15 10.7 3.0 0.22 10.2 3.0 1.2 1 0 0 1 1 1 0 Strabismus protein zf-MYND PF01753.18 EGD89186.2 - 2.4e-08 33.9 9.4 2.4e-08 33.9 9.4 1.9 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 EGD89186.2 - 0.016 15.0 7.8 0.016 15.0 7.8 2.5 2 0 0 2 2 2 0 HIT zinc finger Sterol_MT_C PF08498.10 EGD89187.1 - 2.4e-28 98.2 0.2 4.1e-28 97.5 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EGD89187.1 - 5.8e-18 65.3 0.0 1e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD89187.1 - 8.7e-18 64.8 0.0 1.6e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD89187.1 - 1.4e-15 57.4 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD89187.1 - 3.2e-11 43.3 0.0 5.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD89187.1 - 8.8e-11 42.4 0.0 2.3e-10 41.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 EGD89187.1 - 9.7e-11 41.5 0.0 1.5e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGD89187.1 - 3.4e-09 36.4 0.0 5.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGD89187.1 - 0.0014 18.4 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 EGD89187.1 - 0.0018 17.9 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 EGD89187.1 - 0.0018 17.8 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGD89187.1 - 0.0032 17.0 0.0 0.015 14.9 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EGD89187.1 - 0.0064 16.0 0.0 0.019 14.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_32 PF13679.6 EGD89187.1 - 0.0068 16.4 1.2 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 EGD89187.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 EGD89187.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_24 PF13578.6 EGD89187.1 - 0.15 13.1 0.0 0.48 11.5 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain RRM_1 PF00076.22 EGD89188.1 - 6.6e-10 38.7 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGD89188.1 - 0.008 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EGD89188.1 - 0.057 13.3 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Complex1_LYR PF05347.15 EGD89189.1 - 1.7e-07 31.2 0.1 2.9e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RAC_head PF16717.5 EGD89190.1 - 1.2e-30 106.4 2.6 1.2e-30 106.4 2.6 3.0 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 EGD89190.1 - 8e-18 64.3 0.9 2e-17 63.1 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain MARVEL PF01284.23 EGD89191.1 - 2.4e-10 40.6 10.6 3.2e-10 40.2 10.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4181 PF13789.6 EGD89191.1 - 0.075 13.3 2.6 0.087 13.1 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) ThrE PF06738.12 EGD89191.1 - 0.24 10.7 3.7 0.1 12.0 1.1 1.7 2 1 0 2 2 2 0 Putative threonine/serine exporter Glyco_hydro_76 PF03663.14 EGD89192.1 - 4.8e-160 533.0 6.1 5.5e-160 532.8 6.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGD89192.1 - 0.00024 20.3 8.1 0.0091 15.1 0.1 3.1 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 PFK PF00365.20 EGD89193.1 - 2.8e-192 637.2 0.1 1.4e-106 356.0 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 EGD89193.1 - 0.044 13.4 0.1 0.17 11.5 0.1 2.0 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Med17 PF10156.9 EGD89194.2 - 4e-76 256.6 0.1 5.5e-76 256.1 0.1 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Prenylcys_lyase PF07156.14 EGD89194.2 - 0.056 12.5 0.1 0.091 11.9 0.1 1.2 1 0 0 1 1 1 0 Prenylcysteine lyase ISN1 PF06437.11 EGD89195.1 - 8.3e-196 650.7 0.0 9.3e-196 650.6 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase eIF-5a PF01287.20 EGD89195.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold HNH_2 PF13391.6 EGD89196.1 - 2.4e-12 46.8 0.6 6.1e-12 45.5 0.6 1.7 1 0 0 1 1 1 1 HNH endonuclease p450 PF00067.22 EGD89197.1 - 5.5e-49 167.2 0.0 7.2e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_4 PF13894.6 EGD89199.2 - 1.8 9.6 4.7 4.7 8.3 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Methyltransf_33 PF10017.9 EGD89201.1 - 9e-71 238.5 0.0 1.2e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent HECW1_helix PF18436.1 EGD89201.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 DAO PF01266.24 EGD89202.1 - 7.9e-29 101.3 0.0 1e-28 100.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 EGD89202.1 - 6.7e-05 23.2 0.0 0.00042 20.6 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 EGD89202.1 - 0.00041 20.4 0.0 0.042 13.9 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGD89202.1 - 0.0019 18.4 0.0 0.0058 16.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EGD89202.1 - 0.0076 16.5 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain K_oxygenase PF13434.6 EGD89202.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) cNMP_binding PF00027.29 EGD89203.1 - 3.2e-29 100.9 2.3 2.1e-19 69.4 0.0 5.5 5 1 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.22 EGD89203.1 - 1.5e-18 67.7 5.5 2e-13 51.0 1.7 3.0 3 0 0 3 3 3 2 Patatin-like phospholipase zinc_ribbon_10 PF10058.9 EGD89204.1 - 1.1e-18 66.6 0.1 1.8e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein GRIP PF01465.20 EGD89205.1 - 8e-15 54.5 0.2 1.7e-14 53.5 0.2 1.6 1 0 0 1 1 1 1 GRIP domain GAS PF13851.6 EGD89205.1 - 1.1e-05 24.8 125.5 0.011 15.1 12.0 8.9 4 2 5 9 9 9 5 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EGD89205.1 - 8.1e-05 21.6 131.9 0.0014 17.6 16.1 7.7 3 2 4 7 7 7 4 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EGD89205.1 - 0.00019 21.5 39.6 0.18 11.9 1.5 7.1 6 2 1 7 7 7 3 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 EGD89205.1 - 0.0004 20.1 121.1 0.012 15.2 47.2 6.9 3 2 3 6 6 5 3 Intermediate filament protein CALCOCO1 PF07888.11 EGD89205.1 - 0.0014 17.5 139.3 0.0025 16.8 23.5 6.0 3 2 2 5 5 5 3 Calcium binding and coiled-coil domain (CALCOCO1) like HMMR_N PF15905.5 EGD89205.1 - 0.0017 17.9 129.6 0.13 11.8 12.3 8.3 3 2 5 8 8 8 4 Hyaluronan mediated motility receptor N-terminal Lebercilin PF15619.6 EGD89205.1 - 0.0031 17.2 10.7 0.0031 17.2 10.7 7.9 4 2 3 8 8 7 3 Ciliary protein causing Leber congenital amaurosis disease KASH_CCD PF14662.6 EGD89205.1 - 0.01 15.7 3.1 0.01 15.7 3.1 9.1 3 2 4 9 9 8 0 Coiled-coil region of CCDC155 or KASH DHR10 PF18595.1 EGD89205.1 - 0.012 15.7 13.2 0.012 15.7 13.2 11.2 5 2 4 12 12 11 0 Designed helical repeat protein 10 domain MAD PF05557.13 EGD89205.1 - 0.013 13.9 123.4 0.0053 15.2 5.7 6.4 3 2 3 6 6 6 0 Mitotic checkpoint protein CENP-F_leu_zip PF10473.9 EGD89205.1 - 0.021 14.8 143.0 0.047 13.7 14.7 9.7 3 2 4 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4490 PF14892.6 EGD89205.1 - 0.035 14.2 0.0 0.22 11.6 0.0 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) Myosin_tail_1 PF01576.19 EGD89205.1 - 0.072 10.9 137.8 0.028 12.3 16.2 3.2 3 0 0 3 3 3 0 Myosin tail TolA_bind_tri PF16331.5 EGD89205.1 - 0.12 12.5 0.1 0.12 12.5 0.1 11.1 7 4 4 12 12 12 0 TolA binding protein trimerisation Bap31_Bap29_C PF18035.1 EGD89205.1 - 0.19 11.8 0.1 0.19 11.8 0.1 9.9 8 3 0 8 8 8 0 Bap31/Bap29 cytoplasmic coiled-coil domain ATG16 PF08614.11 EGD89205.1 - 0.31 11.2 160.9 0.14 12.4 25.7 10.1 3 2 4 9 9 9 0 Autophagy protein 16 (ATG16) EzrA PF06160.12 EGD89205.1 - 0.32 9.1 96.8 0.011 13.9 42.6 7.1 3 2 2 6 6 6 0 Septation ring formation regulator, EzrA FPP PF05911.11 EGD89205.1 - 0.32 9.1 130.7 0.95 7.6 21.8 6.7 1 1 5 7 7 7 0 Filament-like plant protein, long coiled-coil DUF641 PF04859.12 EGD89205.1 - 1.9 8.8 106.0 0.21 11.9 10.4 10.6 6 4 3 10 10 9 0 Plant protein of unknown function (DUF641) Acetyltransf_1 PF00583.25 EGD89206.2 - 6.3e-18 65.1 0.0 8.7e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGD89206.2 - 3e-08 34.0 0.0 5.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD89206.2 - 1.2e-07 31.6 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EGD89206.2 - 1.9e-06 27.8 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGD89206.2 - 1.4e-05 25.8 0.0 2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGD89206.2 - 0.021 14.3 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EGD89206.2 - 0.033 14.3 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EGD89206.2 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2838 PF10998.8 EGD89207.1 - 0.016 15.4 1.1 0.04 14.2 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2838) AA_permease_2 PF13520.6 EGD89208.1 - 2.9e-62 210.9 49.6 3.6e-62 210.6 49.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD89208.1 - 2.9e-11 42.6 45.0 3.8e-11 42.3 45.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD89209.2 - 7.4e-24 84.2 5.7 8.5e-24 84.0 5.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD89209.2 - 2.8e-08 33.0 2.4 3.4e-08 32.8 2.4 1.1 1 0 0 1 1 1 1 Amino acid permease Brr6_like_C_C PF10104.9 EGD89210.2 - 4.9e-42 142.9 0.0 7.3e-42 142.3 0.0 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain GtrA PF04138.14 EGD89210.2 - 0.044 14.0 0.3 0.079 13.2 0.3 1.3 1 0 0 1 1 1 0 GtrA-like protein Nucleo_P87 PF07267.11 EGD89210.2 - 2.1 7.1 7.2 2.9 6.6 7.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Fungal_trans_2 PF11951.8 EGD89211.1 - 4.6e-96 322.0 2.1 5.4e-96 321.7 2.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD89211.1 - 8.9e-11 41.7 10.0 8.9e-11 41.7 10.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_binding_1 PF01035.20 EGD89214.1 - 4.4e-26 90.8 0.0 5.8e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain PHINT_rpt PF14882.6 EGD89214.1 - 0.13 12.5 0.2 0.28 11.5 0.2 1.5 1 0 0 1 1 1 0 Phage-integrase repeat unit DUF812 PF05667.11 EGD89215.1 - 0.0047 15.9 0.1 0.0054 15.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Macoilin PF09726.9 EGD89215.1 - 0.021 13.4 0.3 0.026 13.1 0.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF1192 PF06698.11 EGD89215.1 - 0.088 12.9 1.0 0.21 11.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Bap31_Bap29_C PF18035.1 EGD89215.1 - 0.093 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain HAUS5 PF14817.6 EGD89215.1 - 0.14 10.9 1.8 0.2 10.4 1.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Pkinase_fungal PF17667.1 EGD89216.1 - 1.6e-132 442.2 0.0 2.1e-132 441.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGD89216.1 - 9.7e-05 21.8 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Bud13 PF09736.9 EGD89217.1 - 2.7e-49 167.3 1.9 2.7e-49 167.3 1.9 3.0 2 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex SPATIAL PF15256.6 EGD89217.1 - 5.9 7.2 9.1 0.7 10.2 4.6 1.7 2 0 0 2 2 2 0 SPATIAL Pkinase PF00069.25 EGD89218.2 - 4.3e-32 111.5 0.1 4.8e-23 81.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD89218.2 - 2.8e-11 43.2 0.1 1.3e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD89218.2 - 0.069 11.9 2.8 0.041 12.6 0.4 1.8 1 1 1 2 2 2 0 Fungal protein kinase Herpes_DNAp_acc PF04929.12 EGD89218.2 - 0.27 10.2 2.6 0.51 9.3 2.6 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Metallophos PF00149.28 EGD89219.1 - 4.7e-15 56.6 2.2 6.2e-15 56.2 2.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGD89219.1 - 8e-08 32.6 1.4 1.4e-06 28.6 1.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.6 EGD89219.1 - 0.013 14.2 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 MutL protein Ras PF00071.22 EGD89221.1 - 9.4e-36 122.9 0.0 4.7e-34 117.3 0.0 2.0 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGD89221.1 - 4.4e-28 97.9 0.0 7.7e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD89221.1 - 1.9e-10 40.4 0.0 2.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGD89221.1 - 0.00045 20.3 0.0 0.00075 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGD89221.1 - 0.0012 19.3 0.1 0.0023 18.4 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGD89221.1 - 0.014 15.7 0.0 0.037 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 EGD89221.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGD89221.1 - 0.061 13.1 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EGD89221.1 - 0.082 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 EGD89221.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 EGD89221.1 - 0.096 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGD89221.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 EGD89221.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGD89221.1 - 0.17 11.4 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MFS_1 PF07690.16 EGD89222.1 - 1.2e-24 86.9 69.1 1.6e-18 66.7 42.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGD89222.1 - 4.7e-09 35.3 14.2 2.8e-07 29.5 7.9 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 EGD89222.1 - 0.58 9.4 31.4 4.3 6.5 31.4 2.3 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Vma12 PF11712.8 EGD89223.1 - 0.7 9.9 3.6 5.7 7.0 3.6 2.0 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pkinase PF00069.25 EGD89224.2 - 1.2e-14 54.4 0.3 5.9e-07 29.1 0.2 3.3 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD89224.2 - 0.088 12.1 0.1 7.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase Synaptobrevin PF00957.21 EGD89226.1 - 8.7e-14 51.1 0.2 1.3e-13 50.5 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGD89226.1 - 1.6e-11 44.1 0.0 3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Amidohydro_2 PF04909.14 EGD89226.1 - 0.044 13.6 0.0 0.066 13.0 0.0 1.4 1 1 0 1 1 1 0 Amidohydrolase Sec63 PF02889.16 EGD89227.1 - 1.2e-122 408.0 0.0 3.7e-77 258.9 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGD89227.1 - 2e-53 180.8 1.3 2.3e-26 92.7 1.5 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EGD89227.1 - 1.2e-22 80.7 0.0 8.2e-11 42.2 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGD89227.1 - 1.2e-15 57.8 0.1 4e-07 30.4 0.0 4.1 4 2 0 4 4 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGD89227.1 - 3e-08 34.0 0.2 0.002 18.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EGD89227.1 - 1.5e-07 31.4 0.4 0.0012 18.6 0.6 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGD89227.1 - 2.5e-05 24.6 1.8 0.0019 18.6 1.2 2.6 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 EGD89227.1 - 0.0015 18.7 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal helicase PWI domain T2SSE PF00437.20 EGD89227.1 - 0.0065 15.6 0.0 2.3 7.2 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 EGD89227.1 - 0.011 15.3 0.0 0.67 9.4 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 EGD89227.1 - 0.034 13.7 0.1 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGD89227.1 - 0.058 13.1 0.1 3.6 7.3 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein DEK_C PF08766.11 EGD89227.1 - 0.074 13.0 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 DEK C terminal domain TniB PF05621.11 EGD89227.1 - 0.2 11.0 3.8 30 3.9 0.4 3.8 3 1 0 4 4 4 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 EGD89227.1 - 0.6 9.4 2.2 0.78 9.0 0.8 1.9 2 1 0 2 2 2 0 FtsK/SpoIIIE family Profilin PF00235.19 EGD89230.1 - 3e-48 163.3 0.0 3.3e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Profilin Got1 PF04178.12 EGD89231.2 - 2.4e-13 50.5 7.4 2.9e-13 50.2 7.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family YL1_C PF08265.11 EGD89232.1 - 5.6e-17 61.2 0.3 8.9e-17 60.5 0.3 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Gag_p12 PF01141.18 EGD89232.1 - 0.22 11.9 2.8 0.19 12.1 0.6 2.0 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 DASH_Dad4 PF08650.10 EGD89233.1 - 1.2e-18 66.8 2.8 1.6e-18 66.5 2.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 Actin PF00022.19 EGD89234.1 - 7.2e-54 182.9 0.0 2.9e-30 105.2 0.0 2.4 1 1 1 2 2 2 2 Actin bZIP_1 PF00170.21 EGD89235.2 - 1.8e-07 31.1 8.9 1.3e-06 28.4 9.0 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGD89235.2 - 0.56 10.3 11.6 5.5 7.1 10.1 2.9 2 1 0 2 2 2 0 Basic region leucine zipper ERM PF00769.19 EGD89236.1 - 3.3e-05 23.8 35.9 6e-05 23.0 35.9 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family HSDR_N_2 PF13588.6 EGD89236.1 - 5e-05 23.2 0.0 0.23 11.4 0.0 2.8 3 0 0 3 3 3 2 Type I restriction enzyme R protein N terminus (HSDR_N) APH PF01636.23 EGD89236.1 - 0.00018 21.5 0.1 0.00018 21.5 0.1 3.4 2 2 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD89236.1 - 0.00074 19.2 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EGD89236.1 - 0.0039 16.6 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Anoctamin PF04547.12 EGD89237.2 - 2e-65 221.4 0.3 2.6e-65 221.0 0.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Pex2_Pex12 PF04757.14 EGD89237.2 - 0.02 14.5 0.1 0.083 12.5 0.0 2.0 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region CS PF04969.16 EGD89238.1 - 8.9e-17 61.9 0.1 1.9e-16 60.8 0.1 1.6 1 0 0 1 1 1 1 CS domain CE2_N PF17996.1 EGD89238.1 - 0.094 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal Spt5-NGN PF03439.13 EGD89239.2 - 4.1e-23 81.1 0.0 7.4e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 EGD89239.2 - 4.3e-18 65.6 46.5 3e-17 62.9 12.6 3.9 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 EGD89239.2 - 4e-11 42.5 14.5 0.0026 17.6 1.6 5.3 5 0 0 5 5 5 3 KOW motif Spt5_N PF11942.8 EGD89239.2 - 0.00026 21.9 0.0 0.00047 21.1 0.0 1.5 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 EGD89239.2 - 0.00057 20.1 9.2 0.0074 16.5 0.1 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3912) DUF1506 PF07405.11 EGD89239.2 - 0.16 12.2 0.2 0.81 9.9 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1506) Acyl-CoA_dh_1 PF00441.24 EGD89240.2 - 2.1e-41 141.6 0.3 2.9e-41 141.2 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGD89240.2 - 2.5e-21 75.7 0.1 4.2e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGD89240.2 - 4.1e-20 72.5 0.0 8.2e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 EGD89240.2 - 7.2e-20 70.9 0.4 1.4e-19 70.0 0.4 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 EGD89240.2 - 3.6e-09 37.0 0.0 6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 EGD89240.2 - 0.2 12.2 0.1 0.77 10.3 0.0 2.0 2 0 0 2 2 2 0 C6 domain RPN2_C PF18004.1 EGD89241.1 - 7.4e-58 195.0 8.3 7.4e-58 195.0 8.3 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EGD89241.1 - 1.8e-32 110.1 24.9 7.7e-10 38.7 0.0 8.8 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGD89241.1 - 4e-22 78.4 0.5 6.7e-16 58.5 0.0 3.9 3 1 1 4 4 3 2 HEAT repeats HEAT_EZ PF13513.6 EGD89241.1 - 8.7e-09 35.7 0.1 0.019 15.5 0.0 4.0 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 EGD89241.1 - 4.1e-06 26.6 0.1 1.8 9.0 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 EGD89241.1 - 0.0025 17.8 0.0 0.18 11.9 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EGD89241.1 - 0.0078 16.8 2.3 1.1 10.1 0.0 4.0 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat GCIP PF13324.6 EGD89241.1 - 0.095 12.3 4.4 0.19 11.3 4.4 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting FAM178 PF14816.6 EGD89241.1 - 0.45 9.4 1.8 0.91 8.4 1.8 1.4 1 0 0 1 1 1 0 Family of unknown function, FAM178 DUF913 PF06025.12 EGD89241.1 - 4.8 6.0 9.4 3.5 6.5 1.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 EGD89241.1 - 8.5 6.7 18.3 0.18 12.1 2.9 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TMF_TATA_bd PF12325.8 EGD89242.1 - 0.0003 21.0 5.5 0.0003 21.0 5.5 3.6 3 2 1 4 4 4 1 TATA element modulatory factor 1 TATA binding TolA_bind_tri PF16331.5 EGD89242.1 - 0.00051 20.1 2.2 0.00051 20.1 2.2 2.9 2 0 0 2 2 2 1 TolA binding protein trimerisation ABC_tran_CTD PF16326.5 EGD89242.1 - 0.0051 17.0 0.7 0.0051 17.0 0.7 3.9 4 1 0 4 4 4 1 ABC transporter C-terminal domain CorA PF01544.18 EGD89242.1 - 0.0053 16.1 0.3 0.016 14.5 0.3 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2730 PF10805.8 EGD89242.1 - 0.011 15.8 1.4 0.011 15.8 1.4 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF2730) DNA_repr_REX1B PF14966.6 EGD89242.1 - 0.044 14.4 1.0 0.16 12.6 1.0 2.0 1 0 0 1 1 1 0 DNA repair REX1-B Spc7 PF08317.11 EGD89242.1 - 0.22 10.4 17.3 0.12 11.3 5.9 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF465 PF04325.13 EGD89242.1 - 0.36 10.9 6.5 3.9 7.6 3.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF465) DUF1515 PF07439.11 EGD89242.1 - 0.41 10.7 4.2 0.51 10.4 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) FlgN PF05130.12 EGD89242.1 - 0.77 10.3 17.6 2.6 8.6 0.4 3.3 3 0 0 3 3 3 0 FlgN protein WDCP PF15390.6 EGD89242.1 - 1.2 7.4 7.9 1.1 7.6 6.6 1.4 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family UPF0184 PF03670.13 EGD89242.1 - 2.6 8.5 5.4 4.8 7.7 0.2 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) APG6_N PF17675.1 EGD89242.1 - 3.1 8.3 27.0 0.59 10.7 6.5 3.9 2 1 2 4 4 4 0 Apg6 coiled-coil region DUF1090 PF06476.12 EGD89242.1 - 3.8 7.7 8.0 0.38 10.9 3.0 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1090) Allexi_40kDa PF05549.11 EGD89242.1 - 3.8 6.9 10.3 0.24 10.9 0.5 3.1 3 0 0 3 3 3 0 Allexivirus 40kDa protein DUF2802 PF10975.8 EGD89242.1 - 4.2 7.6 7.4 4.5 7.5 0.3 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2802) MutS_IV PF05190.18 EGD89242.1 - 8.4 6.8 7.2 45 4.5 0.3 3.7 4 0 0 4 4 4 0 MutS family domain IV Abhydrolase_1 PF00561.20 EGD89243.1 - 0.0005 19.8 0.2 0.0015 18.2 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGD89243.1 - 0.0018 17.9 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EGD89243.1 - 0.0045 16.5 3.3 0.0096 15.4 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGD89243.1 - 0.083 12.1 0.0 0.66 9.2 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 APH PF01636.23 EGD89244.2 - 5.7e-11 42.8 0.1 7.6e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD89244.2 - 3e-05 23.7 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EGD89244.2 - 0.00051 19.7 0.0 0.00064 19.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EGD89244.2 - 0.0049 16.3 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Med8 PF10232.9 EGD89250.1 - 4.9e-61 206.3 1.0 6.6e-61 205.9 1.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 PQ-loop PF04193.14 EGD89251.1 - 4.4e-19 68.0 13.8 1.9e-12 46.7 1.6 3.2 3 0 0 3 3 3 2 PQ loop repeat UbiA PF01040.18 EGD89252.2 - 1.5e-56 191.5 16.6 1.5e-56 191.5 16.6 1.7 2 0 0 2 2 2 1 UbiA prenyltransferase family Zn_clus PF00172.18 EGD89253.2 - 2.7e-09 37.0 6.6 2.7e-09 37.0 6.6 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGD89253.2 - 3.7e-05 22.7 0.1 5.4e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CTP_transf_like PF01467.26 EGD89256.1 - 0.11 12.7 5.2 4.6 7.4 5.2 2.5 1 1 0 1 1 1 0 Cytidylyltransferase-like WD40 PF00400.32 EGD89257.1 - 2.7e-14 53.3 4.2 5.4e-05 23.9 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat TFIIA PF03153.13 EGD89257.1 - 1.1 9.2 34.0 2.8 7.8 34.0 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit mRNA_triPase PF02940.15 EGD89258.2 - 6e-61 206.0 0.0 7.9e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Spt20 PF12090.8 EGD89258.2 - 1.1 8.8 7.5 1.8 8.1 7.5 1.4 1 0 0 1 1 1 0 Spt20 family Kelch_3 PF13415.6 EGD89259.1 - 4e-16 58.9 10.8 3.6e-10 39.9 0.0 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EGD89259.1 - 3.6e-14 52.5 0.5 0.0002 21.3 0.0 5.4 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EGD89259.1 - 7.2e-13 48.3 0.9 0.07 13.5 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EGD89259.1 - 2.8e-11 42.8 0.0 0.031 13.8 0.0 4.1 3 1 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 EGD89259.1 - 2.3e-09 37.0 1.1 0.0089 16.0 0.0 4.1 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 EGD89259.1 - 2.7e-05 24.0 9.2 0.0028 17.6 0.0 5.6 7 0 0 7 7 7 1 Kelch motif AhpC-TSA PF00578.21 EGD89260.1 - 2.2e-29 101.9 0.0 3.3e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGD89260.1 - 8.1e-14 51.6 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGD89260.1 - 8.1e-09 35.2 0.1 1.4e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin bZIP_2 PF07716.15 EGD89263.1 - 3.4e-05 23.8 10.4 5.5e-05 23.2 10.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Aldedh PF00171.22 EGD89266.2 - 4.7e-182 605.6 3.0 5.4e-182 605.4 3.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGD89266.2 - 0.0016 18.0 0.0 0.0052 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Methyltransf_PK PF05891.12 EGD89267.1 - 4.8e-65 219.1 0.0 7.9e-65 218.4 0.0 1.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 EGD89267.1 - 1.6e-07 30.9 0.1 3.4e-07 29.8 0.1 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EGD89267.1 - 4.8e-06 27.2 0.0 1.6e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD89267.1 - 0.00013 22.5 0.0 0.00027 21.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD89267.1 - 0.0017 19.0 0.0 0.0049 17.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD89267.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Bin3 PF06859.12 EGD89267.1 - 0.033 14.8 0.0 0.055 14.1 0.0 1.3 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Sec23_helical PF04815.15 EGD89267.1 - 0.059 13.2 0.1 0.94 9.3 0.1 2.1 1 1 0 1 1 1 0 Sec23/Sec24 helical domain EVE PF01878.18 EGD89268.1 - 4.8e-50 169.4 0.0 4.8e-50 169.4 0.0 1.8 2 1 0 2 2 2 1 EVE domain Ndc1_Nup PF09531.10 EGD89268.1 - 6.2 5.4 7.7 7.3 5.1 7.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 EGD89268.1 - 7.6 5.2 13.7 9.8 4.9 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Endomucin PF07010.12 EGD89268.1 - 8.7 6.2 14.1 13 5.6 14.1 1.2 1 0 0 1 1 1 0 Endomucin Ribophorin_II PF05817.14 EGD89271.1 - 6.2e-29 101.0 0.0 8.5e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II PufQ PF05398.11 EGD89271.1 - 0.011 15.8 1.1 0.26 11.4 0.1 2.3 2 0 0 2 2 2 0 PufQ cytochrome subunit Piwi PF02171.17 EGD89273.2 - 5e-74 249.3 0.0 6.4e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 EGD89273.2 - 3e-05 24.3 0.1 6.7e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 EGD89273.2 - 0.0006 20.0 0.0 0.0018 18.5 0.0 1.9 1 1 0 1 1 1 1 Mid domain of argonaute RIBIOP_C PF04950.12 EGD89273.2 - 0.08 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal GGACT PF06094.12 EGD89274.1 - 5e-15 56.2 0.2 5.9e-15 55.9 0.2 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like adh_short_C2 PF13561.6 EGD89275.1 - 1.2e-59 201.7 0.3 1.4e-59 201.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD89275.1 - 1.7e-50 171.2 1.0 2.2e-50 170.9 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD89275.1 - 3.6e-16 59.6 0.2 4.7e-16 59.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGD89275.1 - 0.0017 17.9 0.4 0.0028 17.2 0.4 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGD89275.1 - 0.0024 17.3 0.2 0.0039 16.6 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase PLA2_B PF01735.18 EGD89280.2 - 3.3e-195 649.2 0.6 3.9e-195 648.9 0.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DAHP_synth_2 PF01474.16 EGD89282.2 - 3.2e-172 573.0 0.0 3.6e-172 572.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family MFS_1 PF07690.16 EGD89284.1 - 3.9e-24 85.3 27.5 3.9e-24 85.3 27.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PHO4 PF01384.20 EGD89284.1 - 0.011 14.8 1.2 0.011 14.8 1.2 2.2 2 0 0 2 2 2 0 Phosphate transporter family Aldose_epim PF01263.20 EGD89285.1 - 6.2e-39 134.1 0.0 7.4e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Rif1_N PF12231.8 EGD89287.1 - 2.8e-124 414.9 0.1 4.3e-124 414.3 0.1 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Glyco_hydro_25 PF01183.20 EGD89288.1 - 3e-40 138.3 0.0 3.5e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Sugar_tr PF00083.24 EGD89290.1 - 1.5e-137 459.1 16.4 1.8e-137 458.9 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGD89290.1 - 1.1e-26 93.7 26.9 1.8e-23 83.0 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGD89290.1 - 4.6e-05 22.2 21.8 0.00066 18.3 9.8 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein BT1 PF03092.16 EGD89290.1 - 0.0087 14.3 0.7 1.9 6.6 0.0 2.3 2 0 0 2 2 2 2 BT1 family Polysacc_synt_4 PF04669.13 EGD89291.1 - 2.1e-22 79.6 0.8 6e-21 74.9 0.8 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Ric8 PF10165.9 EGD89292.2 - 3.9e-88 296.5 0.1 5.2e-88 296.1 0.1 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn NB-LRR PF12061.8 EGD89292.2 - 0.17 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Late blight resistance protein R1 MFS_1 PF07690.16 EGD89295.1 - 1.7e-27 96.3 48.1 1.7e-27 96.3 48.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily OppC_N PF12911.7 EGD89295.1 - 0.99 9.4 9.8 0.64 10.0 0.2 4.2 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C ABC_membrane PF00664.23 EGD89296.1 - 2.7e-88 296.2 29.0 9.2e-48 163.3 10.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGD89296.1 - 1.7e-59 200.2 0.0 2.1e-28 99.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGD89296.1 - 3e-15 56.3 6.0 1.4e-05 24.6 0.5 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGD89296.1 - 8.8e-09 35.0 1.2 0.0013 18.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGD89296.1 - 2.5e-07 31.1 2.7 0.0027 18.0 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGD89296.1 - 3.8e-07 30.7 0.0 0.0044 17.4 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.6 EGD89296.1 - 8.6e-06 25.5 0.1 0.086 12.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EGD89296.1 - 1.4e-05 25.0 0.2 0.26 11.2 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_21 PF13304.6 EGD89296.1 - 2e-05 24.6 8.0 0.45 10.3 0.2 4.7 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGD89296.1 - 2.5e-05 24.9 0.8 0.014 15.9 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGD89296.1 - 0.0001 22.9 0.0 0.74 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 EGD89296.1 - 0.00033 19.6 1.0 0.21 10.4 0.2 3.5 3 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 EGD89296.1 - 0.0015 18.3 1.9 1 9.0 0.2 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EGD89296.1 - 0.0017 18.5 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGD89296.1 - 0.0022 18.1 0.5 0.65 10.1 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase APS_kinase PF01583.20 EGD89296.1 - 0.006 16.5 0.8 5.4 6.9 0.0 3.3 3 0 0 3 3 3 0 Adenylylsulphate kinase SbcCD_C PF13558.6 EGD89296.1 - 0.0065 16.7 0.1 1.1 9.6 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATPase PF06745.13 EGD89296.1 - 0.0072 15.7 0.2 3.5 6.9 0.0 2.7 2 0 0 2 2 2 1 KaiC DUF3987 PF13148.6 EGD89296.1 - 0.0087 15.1 0.1 3.5 6.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA_5 PF07728.14 EGD89296.1 - 0.0089 16.0 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGD89296.1 - 0.015 15.0 0.3 1.8 8.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EGD89296.1 - 0.017 14.9 0.2 9.9 5.8 0.1 3.3 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 EGD89296.1 - 0.017 15.5 0.1 13 6.2 0.0 2.8 3 0 0 3 3 2 0 RNA helicase G-alpha PF00503.20 EGD89296.1 - 0.024 13.8 0.1 0.32 10.1 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA PF00004.29 EGD89296.1 - 0.031 14.7 0.0 2 8.8 0.0 3.3 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGD89296.1 - 0.073 12.6 0.0 10 5.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 EGD89296.1 - 0.096 12.8 5.1 0.84 9.7 0.1 3.3 4 0 0 4 4 3 0 Helicase HerA, central domain NACHT PF05729.12 EGD89296.1 - 0.11 12.5 0.3 37 4.2 0.1 3.3 3 0 0 3 3 3 0 NACHT domain IstB_IS21 PF01695.17 EGD89296.1 - 0.13 12.0 3.2 9 6.0 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein IspD PF01128.19 EGD89296.1 - 0.13 12.0 0.3 0.26 11.0 0.3 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FtsK_SpoIIIE PF01580.18 EGD89296.1 - 0.14 11.4 0.1 20 4.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Guanylate_kin PF00625.21 EGD89296.1 - 0.15 11.7 0.0 9 5.9 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase Cytidylate_kin PF02224.18 EGD89296.1 - 0.16 11.7 0.5 1.7 8.3 0.2 2.4 2 0 0 2 2 2 0 Cytidylate kinase AcrZ PF10766.9 EGD89296.1 - 0.81 9.3 3.7 0.36 10.4 0.1 2.2 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ Methyltransf_23 PF13489.6 EGD89297.2 - 7.6e-18 64.9 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD89297.2 - 1.1e-10 42.0 0.0 3.1e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD89297.2 - 7.6e-08 32.3 0.0 1.4e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD89297.2 - 2.8e-07 31.2 0.2 3.3e-06 27.8 0.0 2.7 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD89297.2 - 4e-07 30.6 0.0 8.1e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGD89297.2 - 0.0046 16.7 0.0 0.0073 16.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EGD89297.2 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGD89297.2 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EGD89297.2 - 0.028 13.9 0.0 0.079 12.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 EGD89297.2 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Med3 PF11593.8 EGD89297.2 - 3.2 6.9 14.8 4.5 6.3 14.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal p450 PF00067.22 EGD89298.1 - 6.6e-60 203.2 0.0 9.3e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4229 PF14012.6 EGD89299.1 - 0.047 13.8 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) RSN1_TM PF13967.6 EGD89299.1 - 0.054 13.3 0.3 0.089 12.6 0.3 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Pkinase PF00069.25 EGD89302.2 - 3.6e-06 26.5 0.0 6.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 EGD89302.2 - 5.2e-06 26.6 0.0 0.046 13.9 0.0 3.0 3 0 0 3 3 3 2 POLO box duplicated region Acetyltransf_3 PF13302.7 EGD89303.1 - 2.1e-27 96.5 0.1 3.5e-27 95.8 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGD89303.1 - 7.2e-05 23.0 0.0 0.0001 22.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EGD89303.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PBAN PF05874.11 EGD89303.1 - 0.035 14.0 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) DHHC PF01529.20 EGD89304.1 - 1.2e-31 109.6 5.5 1.2e-31 109.6 5.5 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase MFS_1 PF07690.16 EGD89305.1 - 2.4e-37 128.7 46.2 8.7e-37 126.8 42.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGD89305.1 - 1e-06 27.5 9.3 1.8e-06 26.7 9.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EGD89307.1 - 7.2e-31 107.4 29.6 7.2e-31 107.4 29.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily APH PF01636.23 EGD89308.1 - 8.7e-14 52.0 0.1 2.5e-13 50.5 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EGD89308.1 - 0.0014 17.9 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase Mei5 PF10376.9 EGD89309.2 - 0.047 13.6 1.5 0.056 13.3 1.5 1.0 1 0 0 1 1 1 0 Double-strand recombination repair protein DNA_mis_repair PF01119.19 EGD89310.2 - 6.1e-11 42.0 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DUF3431 PF11913.8 EGD89311.2 - 1.4e-76 257.0 0.2 1.8e-76 256.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Glyco_transf_54 PF04666.13 EGD89312.1 - 1.5e-14 53.5 0.0 2e-10 40.0 0.0 3.1 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF2754 PF10953.8 EGD89312.1 - 0.0094 16.2 0.3 0.02 15.1 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2754) AAA_12 PF13087.6 EGD89313.1 - 0.0007 19.3 0.0 0.0011 18.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain SET PF00856.28 EGD89314.1 - 5.2e-08 33.4 0.0 7.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 SET domain cobW PF02492.19 EGD89315.1 - 1.9e-42 144.8 0.0 3.6e-42 143.9 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EGD89315.1 - 0.0005 20.0 0.0 0.0018 18.2 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.14 EGD89315.1 - 0.0012 18.7 0.0 0.0064 16.4 0.0 2.2 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 EGD89315.1 - 0.023 15.0 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EGD89315.1 - 0.053 13.3 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EGD89315.1 - 0.12 12.1 0.1 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pox_A32 PF04665.12 EGD89315.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein Orn_Arg_deC_N PF02784.16 EGD89316.1 - 2.8e-82 275.8 0.0 4.5e-82 275.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGD89316.1 - 3.8e-18 65.5 0.0 4.7e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 EGD89316.1 - 0.019 14.4 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Luteo_P1-P2 PF08467.10 EGD89316.1 - 0.23 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase Methyltransf_16 PF10294.9 EGD89317.2 - 2e-50 170.9 0.0 3e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EGD89317.2 - 2.4e-05 25.0 0.1 7e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD89317.2 - 2.6e-05 24.1 0.0 4.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD89317.2 - 4.6e-05 23.2 0.1 0.00024 20.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGD89317.2 - 0.00078 19.0 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGD89317.2 - 0.0017 19.0 1.0 0.0035 18.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGD89317.2 - 0.0094 15.4 0.2 0.016 14.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Bromodomain PF00439.25 EGD89319.1 - 2.3e-22 78.9 0.3 4.2e-22 78.0 0.3 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EGD89319.1 - 6.3e-08 32.9 0.1 1.2e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGD89319.1 - 4.4e-07 29.9 0.3 9.7e-07 28.8 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGD89319.1 - 4.4e-05 23.8 0.3 9.6e-05 22.7 0.2 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD89319.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DSBA PF01323.20 EGD89320.1 - 4.7e-13 49.4 0.0 5.8e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Mitofilin PF09731.9 EGD89324.1 - 3.8e-152 508.4 29.6 5.7e-125 418.6 32.3 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein ATP-synt_B PF00430.18 EGD89324.1 - 0.0093 16.1 20.1 0.19 11.8 8.2 2.8 1 1 1 2 2 2 2 ATP synthase B/B' CF(0) Focal_AT PF03623.13 EGD89324.1 - 0.054 13.5 1.6 0.13 12.2 0.2 2.2 1 1 1 2 2 2 0 Focal adhesion targeting region Ribosomal_L20 PF00453.18 EGD89324.1 - 0.06 13.4 2.1 0.14 12.3 2.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L20 DUF2205 PF10224.9 EGD89324.1 - 0.16 12.0 6.5 0.065 13.2 1.9 2.7 1 1 0 2 2 2 0 Short coiled-coil protein YqhG PF11079.8 EGD89324.1 - 0.46 9.4 3.3 0.78 8.6 3.3 1.3 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function FAD-SLDH PF12318.8 EGD89324.1 - 1.1 9.3 3.2 1.7 8.7 1.1 2.2 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF4363 PF14276.6 EGD89324.1 - 3.4 7.8 9.8 1.6 8.9 0.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) Ras PF00071.22 EGD89325.1 - 8.3e-59 197.8 0.2 9.6e-59 197.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD89325.1 - 2.6e-36 124.5 0.2 4.4e-36 123.7 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD89325.1 - 1.1e-14 54.3 0.1 1.3e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGD89325.1 - 2.8e-07 30.3 0.0 3.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGD89325.1 - 6.2e-07 29.5 0.0 9.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGD89325.1 - 1.4e-06 27.9 0.0 1.7e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGD89325.1 - 2.1e-05 24.5 1.1 0.19 11.6 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EGD89325.1 - 0.011 16.1 0.2 0.028 14.8 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGD89325.1 - 0.056 13.7 0.0 3.1 8.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAT PF03417.16 EGD89325.1 - 0.14 11.8 0.2 0.21 11.3 0.2 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase SUIM_assoc PF16619.5 EGD89327.1 - 1.1 9.3 24.7 8.6 6.5 0.0 3.9 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 EGD89328.2 - 6.5e-05 23.6 2.3 0.018 15.9 0.1 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat LRR19-TM PF15176.6 EGD89328.2 - 0.056 13.4 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF123 PF01986.16 EGD89328.2 - 0.13 12.8 0.1 0.27 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF123 Chitin_synth_2 PF03142.15 EGD89330.1 - 8.7e-290 961.8 0.1 1.4e-289 961.1 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EGD89330.1 - 4.8e-13 49.5 2.6 1.6e-12 47.8 2.6 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGD89330.1 - 2.8e-09 37.2 0.0 7.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGD89330.1 - 0.00013 21.5 0.1 0.0018 17.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGD89330.1 - 0.0094 15.8 0.1 0.084 12.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 OrfB_IS605 PF01385.19 EGD89330.1 - 0.25 11.6 2.8 0.43 10.8 0.8 2.1 2 0 0 2 2 2 0 Probable transposase Selenoprotein_S PF06936.11 EGD89330.1 - 0.67 9.7 4.8 1.4 8.7 4.8 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) Sel1 PF08238.12 EGD89331.2 - 1.8e-38 130.1 31.1 1.6e-05 25.5 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 EGD89331.2 - 0.025 15.2 5.4 2.9 8.7 0.3 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat Mitofilin PF09731.9 EGD89331.2 - 0.049 12.5 6.3 0.069 12.0 6.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PNISR PF15996.5 EGD89331.2 - 8.7 6.6 14.2 2.8 8.2 8.6 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR FAM60A PF15396.6 EGD89331.2 - 9 6.2 9.1 4.2 7.3 4.1 2.3 2 0 0 2 2 2 0 Protein Family FAM60A AF-4 PF05110.13 EGD89331.2 - 9.2 4.2 24.9 0.41 8.7 19.3 1.5 2 0 0 2 2 2 0 AF-4 proto-oncoprotein MFS_1 PF07690.16 EGD89332.2 - 9.5e-42 143.2 63.7 1.9e-40 138.9 63.1 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD89332.2 - 1.9e-14 53.4 9.4 1.9e-14 53.4 9.4 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EGD89332.2 - 2.4e-14 52.7 28.2 5.2e-14 51.6 28.2 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EGD89332.2 - 0.13 10.5 10.1 0.34 9.1 3.6 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_17 PF00332.18 EGD89333.1 - 0.013 15.1 0.7 0.026 14.1 0.2 1.6 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 FAD_binding_2 PF00890.24 EGD89336.1 - 1.1e-81 275.1 0.4 1.4e-81 274.7 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EGD89336.1 - 4.1e-21 74.9 0.1 8.2e-20 70.7 0.0 2.9 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EGD89336.1 - 5.6e-12 45.9 0.6 1.4e-11 44.6 0.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGD89336.1 - 3.2e-10 39.9 1.2 1.2e-09 38.0 1.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGD89336.1 - 2.2e-08 34.2 1.3 8e-08 32.4 0.2 2.5 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGD89336.1 - 1.1e-07 31.4 0.4 1.1e-06 28.1 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGD89336.1 - 1.2e-06 28.1 0.0 0.0076 15.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGD89336.1 - 1.2e-05 24.2 4.2 0.00015 20.6 1.1 2.9 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EGD89336.1 - 0.0001 21.6 1.6 0.027 13.6 0.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 EGD89336.1 - 0.00057 19.2 0.3 0.076 12.2 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EGD89336.1 - 0.0006 19.2 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EGD89336.1 - 0.031 14.8 1.4 6.3 7.4 0.1 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EGD89339.1 - 2e-27 96.1 40.4 2e-27 96.1 40.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ketoacyl-synt PF00109.26 EGD89340.1 - 5.7e-79 265.3 0.0 1.6e-78 263.8 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGD89340.1 - 8.4e-65 219.4 0.0 1.7e-64 218.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EGD89340.1 - 3.7e-61 206.2 0.0 1.7e-60 204.0 0.0 2.1 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 EGD89340.1 - 3.6e-41 139.9 0.2 8.7e-41 138.7 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EGD89340.1 - 8.3e-15 54.9 0.1 1e-12 48.2 0.0 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EGD89340.1 - 1.7e-13 51.0 0.0 4.8e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGD89340.1 - 5.1e-10 39.1 0.0 7.9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 EGD89340.1 - 3.7e-05 23.2 3.5 7.1e-05 22.3 0.8 2.5 3 0 0 3 3 3 1 Thiolase, N-terminal domain adh_short PF00106.25 EGD89340.1 - 0.00014 21.4 0.0 0.0012 18.4 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Fungal_trans PF04082.18 EGD89341.2 - 4.1e-05 22.7 0.0 8.6e-05 21.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 EGD89342.1 - 7.7e-62 208.9 3.5 5.6e-61 206.1 3.5 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD89342.1 - 3.2e-43 147.5 2.5 5.3e-43 146.7 2.5 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD89342.1 - 4.1e-10 39.9 0.3 4.1e-10 39.9 0.3 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EGD89342.1 - 0.031 13.4 0.1 0.046 12.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 EGD89343.1 - 3.5e-21 75.6 0.1 4e-17 62.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGD89343.1 - 2.2e-09 37.2 0.0 1.5e-05 24.6 0.0 2.2 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD89343.1 - 2.2e-07 31.0 0.1 3.9e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 KR domain p450 PF00067.22 EGD89344.2 - 8.6e-31 107.2 0.0 1.1e-30 106.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.12 EGD89345.2 - 2.1e-31 109.0 0.0 4e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGD89345.2 - 1.3e-11 44.4 0.0 2.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGD89345.2 - 7.1e-11 42.3 0.0 1.7e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.28 EGD89345.2 - 2.8e-08 32.8 0.0 5e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Polysacc_synt_2 PF02719.15 EGD89345.2 - 0.1 11.7 0.0 0.2 10.8 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PCI PF01399.27 EGD89346.1 - 3.3e-11 43.6 0.0 8.1e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 EGD89346.1 - 4.5e-07 29.7 0.1 8.8e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TFIIF_beta_N PF17683.1 EGD89347.2 - 1.6e-31 109.8 1.1 3e-31 108.9 1.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 EGD89347.2 - 6.3e-28 96.7 1.4 8.8e-28 96.2 0.3 1.9 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain zf-CCCH PF00642.24 EGD89348.1 - 2.6e-13 49.5 26.0 0.00056 19.8 1.3 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGD89348.1 - 5.4e-08 32.6 28.3 0.0064 16.5 0.5 5.9 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_3 PF15663.5 EGD89348.1 - 0.0014 18.8 12.7 0.11 12.7 1.7 3.7 2 1 1 3 3 3 3 Zinc-finger containing family Torus PF16131.5 EGD89348.1 - 0.0024 18.5 22.2 0.31 11.8 0.9 4.7 1 1 3 4 4 4 3 Torus domain Ebp2 PF05890.12 EGD89348.1 - 0.086 12.4 2.6 0.16 11.5 2.6 1.3 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 zf-C3H1 PF10650.9 EGD89348.1 - 1.2 8.9 0.0 1.2 8.9 0.0 4.0 5 0 0 5 5 5 0 Putative zinc-finger domain bZIP_Maf PF03131.17 EGD89350.1 - 1.3e-05 25.6 14.6 1.3e-05 25.6 14.6 3.1 2 1 1 3 3 3 1 bZIP Maf transcription factor bZIP_2 PF07716.15 EGD89350.1 - 0.00021 21.3 11.6 0.00021 21.3 11.6 3.5 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 EGD89350.1 - 0.00034 20.6 14.6 0.00034 20.6 14.6 3.3 1 1 3 4 4 4 1 bZIP transcription factor DUF1062 PF06353.12 EGD89350.1 - 0.17 12.7 10.2 1.1 10.1 7.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1062) RNA_pol_I_TF PF04090.12 EGD89351.2 - 2.3e-07 30.5 0.0 0.0002 20.9 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor ECM11 PF15463.6 EGD89352.1 - 3.1e-40 137.9 0.5 7.9e-40 136.5 0.0 2.0 2 0 0 2 2 2 1 Extracellular mutant protein 11 FAM216B PF15107.6 EGD89352.1 - 0.029 14.2 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 FAM216B protein family zf-RING_2 PF13639.6 EGD89353.2 - 6.3e-07 29.6 4.1 1e-06 28.9 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGD89353.2 - 2.4e-06 27.2 5.5 4.4e-06 26.3 5.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGD89353.2 - 0.0021 18.1 2.7 0.0042 17.1 2.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGD89353.2 - 0.0069 16.2 3.1 0.012 15.4 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 EGD89353.2 - 0.033 14.1 3.2 0.058 13.3 3.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 EGD89353.2 - 0.037 14.0 3.3 0.06 13.3 3.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Flg_bb_rod PF00460.20 EGD89353.2 - 0.041 13.8 0.6 0.13 12.2 0.6 2.0 1 0 0 1 1 1 0 Flagella basal body rod protein zf-rbx1 PF12678.7 EGD89353.2 - 0.044 14.1 1.9 0.09 13.1 1.9 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 EGD89353.2 - 0.05 13.6 0.9 0.095 12.7 0.9 1.3 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4 PF00097.25 EGD89353.2 - 0.055 13.3 4.7 0.092 12.6 4.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGD89353.2 - 0.066 12.8 2.7 0.11 12.1 2.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 EGD89353.2 - 0.73 10.0 3.5 1.3 9.2 3.5 1.3 1 0 0 1 1 1 0 KIAA1045 RING finger AMP-binding PF00501.28 EGD89356.1 - 2.6e-46 158.1 0.0 3.2e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.16 EGD89358.2 - 2.5e-07 30.0 4.2 1.3e-06 27.6 3.0 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 EGD89361.1 - 7.2e-11 41.5 6.4 2.4e-10 39.8 6.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD89361.1 - 6.3e-06 26.2 11.0 1.3e-05 25.2 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 EGD89361.1 - 1.6 9.1 7.7 0.96 9.8 3.8 2.5 2 0 0 2 2 2 0 Opy2 protein DEAD PF00270.29 EGD89362.1 - 7.3e-26 91.0 0.0 1.2e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EGD89362.1 - 4.9e-18 65.7 0.3 1.8e-17 63.8 0.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EGD89362.1 - 9.1e-14 51.7 0.2 2.3e-12 47.2 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD89362.1 - 0.00019 21.5 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 EGD89362.1 - 0.00062 20.1 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like DUF5414 PF17435.2 EGD89362.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5414) Glyco_transf_20 PF00982.21 EGD89363.2 - 0.0023 16.7 0.0 0.0027 16.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 FKBP_C PF00254.28 EGD89368.1 - 0.00021 21.6 0.0 0.00035 20.8 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FOXP-CC PF16159.5 EGD89368.1 - 0.051 14.2 1.8 5.6 7.7 0.1 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain zf_PR_Knuckle PF18445.1 EGD89368.1 - 0.087 12.7 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 PR zinc knuckle motif zf-C2H2_4 PF13894.6 EGD89368.1 - 0.46 11.5 6.9 22 6.2 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger HEPN_RES_NTD1 PF18870.1 EGD89369.2 - 0.066 13.4 0.3 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 PI3_PI4_kinase PF00454.27 EGD89369.2 - 0.068 13.0 0.1 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase HNH_2 PF13391.6 EGD89370.2 - 6.6e-14 51.8 0.0 1.6e-13 50.6 0.0 1.7 1 1 0 1 1 1 1 HNH endonuclease Ran_BP1 PF00638.18 EGD89371.2 - 1.8e-13 50.8 0.1 3.3e-07 30.6 0.2 2.3 2 0 0 2 2 2 2 RanBP1 domain HSP70 PF00012.20 EGD89372.2 - 0.00013 20.3 0.0 0.00014 20.3 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein ADIP PF11559.8 EGD89373.2 - 0.011 15.9 3.0 0.011 15.9 3.0 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 EGD89373.2 - 0.032 14.3 6.1 1.3 9.1 0.1 2.7 1 1 1 2 2 2 0 Basic region leucine zipper YabA PF06156.13 EGD89373.2 - 0.1 13.2 0.9 0.24 12.1 0.5 1.8 1 1 0 1 1 1 0 Initiation control protein YabA FlxA PF14282.6 EGD89373.2 - 0.3 11.1 5.6 0.14 12.2 1.1 2.2 2 0 0 2 2 2 0 FlxA-like protein MIP-T3_C PF17749.1 EGD89373.2 - 0.39 10.7 5.7 5.8 6.9 0.3 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region MMR_HSR1 PF01926.23 EGD89374.2 - 1.9e-09 37.6 2.2 1.9e-08 34.4 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGD89374.2 - 2.2e-08 33.7 1.4 2.3e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Septin PF00735.18 EGD89374.2 - 0.0006 19.2 0.0 0.0006 19.2 0.0 2.4 2 1 1 3 3 3 1 Septin RsgA_GTPase PF03193.16 EGD89374.2 - 0.001 19.0 0.1 0.001 19.0 0.1 2.1 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 EGD89374.2 - 0.0012 18.4 0.2 0.0028 17.2 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGD89374.2 - 0.0036 17.4 15.7 0.0095 16.0 0.0 3.9 2 2 1 3 3 2 2 Dynamin family Viral_helicase1 PF01443.18 EGD89374.2 - 0.0077 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGD89374.2 - 0.009 16.3 2.5 0.011 16.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EGD89374.2 - 0.021 14.0 0.5 0.051 12.7 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain SRPRB PF09439.10 EGD89374.2 - 0.025 14.0 0.0 0.025 14.0 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF4407 PF14362.6 EGD89374.2 - 0.027 13.8 12.5 0.048 13.0 12.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_tran PF00005.27 EGD89374.2 - 0.065 13.7 0.0 0.065 13.7 0.0 2.5 2 1 0 2 2 1 0 ABC transporter AAA_29 PF13555.6 EGD89374.2 - 0.11 12.2 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fzo_mitofusin PF04799.13 EGD89374.2 - 0.24 11.0 12.2 0.087 12.4 2.1 2.5 1 1 1 2 2 2 0 fzo-like conserved region FtsK_SpoIIIE PF01580.18 EGD89374.2 - 0.24 10.7 0.1 0.24 10.7 0.1 2.1 2 1 0 2 2 2 0 FtsK/SpoIIIE family FUSC PF04632.12 EGD89374.2 - 0.78 8.2 2.1 1.1 7.7 2.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SRP54 PF00448.22 EGD89374.2 - 0.96 9.0 4.6 12 5.5 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain KfrA_N PF11740.8 EGD89374.2 - 2.8 8.6 15.7 0.33 11.7 10.1 2.2 1 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term Exonuc_VII_L PF02601.15 EGD89374.2 - 4.6 6.7 14.0 7 6.1 14.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cu-oxidase_2 PF07731.14 EGD89375.2 - 6.2e-37 126.4 0.1 6.6e-36 123.1 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EGD89375.2 - 1.1e-19 71.1 0.0 3e-19 69.7 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase Yip1 PF04893.17 EGD89376.1 - 2.4e-13 50.2 18.0 4.2e-13 49.4 18.0 1.5 1 1 0 1 1 1 1 Yip1 domain IBR PF01485.21 EGD89377.2 - 0.0033 17.6 6.9 0.0033 17.6 6.9 5.0 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain DMA PF03474.14 EGD89377.2 - 0.068 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif adh_short PF00106.25 EGD89378.1 - 1.7e-83 278.9 5.1 2.7e-43 147.7 0.3 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGD89378.1 - 1.1e-66 224.8 2.6 1.9e-34 119.2 0.2 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EGD89378.1 - 2.6e-32 111.0 0.0 5e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EGD89378.1 - 3.7e-24 85.6 2.9 2.7e-11 43.7 0.3 2.7 2 1 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 EGD89378.1 - 6.6e-05 22.3 0.6 0.0099 15.2 0.5 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EGD89378.1 - 1.3 8.9 5.4 14 5.5 0.2 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.12 EGD89378.1 - 3.6 7.6 5.4 20 5.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF543) TsaE PF02367.17 EGD89379.2 - 0.016 15.2 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 EGD89379.2 - 0.039 13.2 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain LysM PF01476.20 EGD89380.1 - 0.071 13.2 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 LysM domain Fungal_trans PF04082.18 EGD89381.2 - 4.9e-17 61.8 0.5 1.2e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain UPF0492 PF15744.5 EGD89381.2 - 0.32 10.2 6.4 0.53 9.5 6.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 Protocadherin PF08374.11 EGD89381.2 - 1.3 8.9 9.0 6.9 6.6 9.0 2.2 1 1 0 1 1 1 0 Protocadherin Glyco_hydro_18 PF00704.28 EGD89382.1 - 8.9e-51 173.5 0.1 1.5e-50 172.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 EGD89382.1 - 3.8e-30 104.2 0.8 1.3e-29 102.5 0.8 2.0 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.20 EGD89382.1 - 3.8e-07 30.1 1.0 0.016 15.3 0.0 3.4 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 EGD89382.1 - 4.2e-05 23.9 9.0 4.2e-05 23.9 9.0 3.3 3 0 0 3 3 3 1 Chitin recognition protein LysM PF01476.20 EGD89384.2 - 1.7e-19 69.6 1.0 6.2e-05 23.0 0.0 3.2 3 0 0 3 3 3 3 LysM domain UPF0203 PF05254.12 EGD89384.2 - 0.21 11.9 3.1 3.5 7.9 0.7 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Sporozoite_P67 PF05642.11 EGD89384.2 - 1 7.3 10.8 1.5 6.8 10.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 EGD89384.2 - 3.7 7.5 27.5 6.5 6.7 27.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 EGD89384.2 - 5.5 7.4 12.0 16 6.0 12.0 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PigN PF04987.14 EGD89385.1 - 1.7e-162 541.5 30.2 1.7e-162 541.5 30.2 1.4 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EGD89385.1 - 4.8e-09 36.3 3.7 1e-07 31.9 3.3 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGD89385.1 - 1.1e-08 34.8 0.1 1.9e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EGD89385.1 - 3.8e-05 23.2 0.0 6.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily LolB PF03550.14 EGD89385.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB SOBP PF15279.6 EGD89386.2 - 1.3 9.6 10.5 1.8 9.1 10.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein GREB1 PF15782.5 EGD89386.2 - 3.4 4.7 10.0 3.9 4.4 10.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 EGD89386.2 - 3.4 6.1 8.5 4.6 5.7 8.5 1.2 1 0 0 1 1 1 0 Macoilin family MPDZ_u10 PF16667.5 EGD89386.2 - 7.9 7.5 9.4 0.46 11.4 2.2 2.6 2 1 2 4 4 4 0 Unstructured region 10 on multiple PDZ protein AAA PF00004.29 EGD89387.1 - 4.7e-37 127.4 0.0 1.3e-36 125.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD89387.1 - 6.8e-09 35.4 0.0 1.5e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 EGD89387.1 - 1.3e-05 25.2 0.0 8.9e-05 22.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EGD89387.1 - 1.8e-05 24.8 0.1 0.00022 21.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGD89387.1 - 2.1e-05 25.0 0.6 0.00015 22.2 0.1 2.6 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 EGD89387.1 - 2.6e-05 24.0 0.0 5.7e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGD89387.1 - 0.00021 21.5 0.0 0.00051 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGD89387.1 - 0.00036 20.8 0.1 0.0052 17.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EGD89387.1 - 0.00053 20.2 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGD89387.1 - 0.00056 20.5 0.1 0.0025 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGD89387.1 - 0.00077 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGD89387.1 - 0.0011 18.4 0.1 0.002 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EGD89387.1 - 0.0012 18.5 0.1 0.027 14.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGD89387.1 - 0.0013 19.0 0.0 0.005 17.2 0.0 2.1 1 1 1 2 2 2 1 RNA helicase TniB PF05621.11 EGD89387.1 - 0.003 17.0 0.0 2.9 7.3 0.0 2.6 1 1 1 2 2 2 2 Bacterial TniB protein Parvo_NS1 PF01057.17 EGD89387.1 - 0.0041 16.2 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NACHT PF05729.12 EGD89387.1 - 0.0045 16.9 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 EGD89387.1 - 0.0083 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGD89387.1 - 0.009 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EGD89387.1 - 0.0094 16.1 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 EGD89387.1 - 0.0099 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EGD89387.1 - 0.012 15.6 0.1 0.038 13.9 0.0 1.8 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_11 PF13086.6 EGD89387.1 - 0.023 14.5 0.5 0.27 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGD89387.1 - 0.028 14.9 0.2 0.084 13.4 0.0 2.0 2 1 0 2 2 1 0 ABC transporter DUF815 PF05673.13 EGD89387.1 - 0.042 13.0 0.0 0.086 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EGD89387.1 - 0.049 13.1 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EGD89387.1 - 0.066 13.1 0.0 0.24 11.3 0.0 1.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea CPT PF07931.12 EGD89387.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_6 PF12774.7 EGD89387.1 - 0.069 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 EGD89387.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 EGD89387.1 - 0.081 12.1 0.0 0.36 10.0 0.0 2.0 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 EGD89387.1 - 0.13 11.6 0.0 0.57 9.5 0.0 1.9 1 1 1 2 2 2 0 KaiC Viral_helicase1 PF01443.18 EGD89387.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase EOS1 PF12326.8 EGD89387.1 - 0.19 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 N-glycosylation protein Cys_Met_Meta_PP PF01053.20 EGD89388.1 - 7.2e-142 472.4 0.0 8.4e-142 472.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGD89388.1 - 0.00031 20.2 0.0 0.001 18.5 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EGD89388.1 - 0.019 14.2 0.0 0.058 12.7 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase ZFYVE21_C PF16696.5 EGD89388.1 - 0.11 12.3 0.0 1.3 8.9 0.0 2.5 3 0 0 3 3 3 0 Zinc finger FYVE domain-containing protein 21 C-terminus MFS_1 PF07690.16 EGD89389.1 - 7.7e-37 127.0 33.5 8.5e-26 90.7 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipoprotein_16 PF03923.13 EGD89390.1 - 0.059 13.0 0.3 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized lipoprotein MTP18 PF10558.9 EGD89391.1 - 5.8e-82 273.7 0.0 1.2e-81 272.7 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) ATP19 PF11022.8 EGD89392.1 - 1.1e-25 89.8 0.1 1.3e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit K AAT PF03417.16 EGD89393.2 - 2.5e-26 92.8 0.0 2.9e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase ACPS PF01648.20 EGD89394.1 - 1.3e-14 54.3 0.0 1.6e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EGD89394.1 - 0.013 15.6 1.2 3.3 7.9 0.1 2.6 3 0 0 3 3 3 0 4'-phosphopantetheinyl transferase N-terminal domain ATPase-cat_bd PF12156.8 EGD89396.1 - 0.22 12.3 0.9 0.58 10.9 0.7 1.8 1 1 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase PHP PF02811.19 EGD89397.1 - 7.2e-12 45.9 0.0 1e-11 45.4 0.0 1.2 1 0 0 1 1 1 1 PHP domain IFP_35_N PF07334.13 EGD89397.1 - 0.13 12.4 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus AA_permease PF00324.21 EGD89398.1 - 9.6e-133 443.3 47.0 1.2e-132 443.0 47.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD89398.1 - 2.2e-24 86.1 53.3 3.7e-24 85.3 53.3 1.3 1 1 0 1 1 1 1 Amino acid permease FKBP_C PF00254.28 EGD89399.2 - 8.4e-07 29.2 0.0 9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase F-box PF00646.33 EGD89401.2 - 0.00031 20.6 0.8 0.0011 18.8 0.8 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGD89401.2 - 0.017 15.0 0.2 0.034 14.0 0.2 1.5 1 0 0 1 1 1 0 F-box CLTH PF10607.9 EGD89401.2 - 0.21 11.5 0.4 0.34 10.8 0.4 1.2 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain EAP30 PF04157.16 EGD89403.1 - 4.2e-45 153.9 3.2 5.5e-45 153.5 3.2 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 EGD89403.1 - 9.9e-22 76.1 2.5 9.9e-22 76.1 2.5 2.7 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 EGD89403.1 - 4.1e-21 74.9 0.0 9.9e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 EGD89403.1 - 0.002 17.4 9.5 0.0044 16.3 0.2 2.8 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 EGD89403.1 - 0.0022 18.0 9.6 0.0025 17.8 0.9 3.3 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger GRAM PF02893.20 EGD89403.1 - 0.022 14.7 0.0 0.053 13.4 0.0 1.6 2 0 0 2 2 2 0 GRAM domain Cas_CXXC_CXXC PF09706.10 EGD89403.1 - 0.037 14.2 1.4 0.56 10.5 0.1 2.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-MIZ PF02891.20 EGD89403.1 - 0.09 12.5 0.6 0.23 11.2 0.6 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger SAC3_GANP PF03399.16 EGD89404.1 - 6.3e-25 88.2 1.9 1.1e-22 80.8 1.9 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EGD89404.1 - 3.5e-05 23.8 1.3 5.3e-05 23.2 0.2 1.8 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SH3_1 PF00018.28 EGD89405.1 - 1.9e-25 88.2 1.5 2e-11 43.3 0.0 3.2 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 EGD89405.1 - 3.2e-14 52.5 2.5 4.6e-06 26.4 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.24 EGD89405.1 - 2.1e-13 50.2 0.0 4.5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 EGD89405.1 - 5.8e-11 41.9 0.0 6.2e-06 25.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 EGD89405.1 - 1.7e-06 27.8 0.4 3.5e-06 26.8 0.4 1.5 1 0 0 1 1 1 1 PB1 domain IHABP4_N PF16174.5 EGD89405.1 - 1.5 9.4 9.3 0.39 11.3 0.1 2.5 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal AFG1_ATPase PF03969.16 EGD89406.2 - 1.2e-90 304.1 0.0 2.1e-85 286.8 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EGD89406.2 - 0.00018 21.9 0.3 0.13 12.6 0.0 3.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EGD89406.2 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGD89406.2 - 0.0038 17.7 0.0 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGD89406.2 - 0.029 14.6 0.0 0.12 12.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 EGD89406.2 - 0.099 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EGD89406.2 - 0.16 11.9 0.0 0.52 10.2 0.0 1.9 1 1 0 1 1 1 0 NACHT domain dCMP_cyt_deam_1 PF00383.23 EGD89408.1 - 3.2e-06 26.9 0.0 4.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF1774 PF08611.10 EGD89409.1 - 1.6e-29 102.1 2.7 1.6e-29 102.1 2.7 2.1 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Peptidase_M28 PF04389.17 EGD89410.2 - 3.9e-23 82.2 0.0 6.5e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGD89410.2 - 0.00028 20.6 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.6 EGD89411.1 - 9.5e-26 90.8 11.3 9.5e-26 90.8 11.3 1.6 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 EGD89411.1 - 0.0044 17.0 0.0 0.094 12.7 0.0 2.5 2 0 0 2 2 2 1 R3H domain PIN_8 PF18476.1 EGD89411.1 - 0.29 11.0 4.3 0.42 10.4 4.3 1.2 1 0 0 1 1 1 0 PIN like domain TipAS PF07739.13 EGD89411.1 - 0.96 10.0 5.0 1.7 9.2 5.0 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Hist_deacetyl PF00850.19 EGD89412.2 - 4.1e-50 171.0 0.0 7.7e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain zf-AN1 PF01428.16 EGD89413.2 - 2.3e-24 85.3 26.0 2.6e-12 46.7 9.5 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 EGD89413.2 - 0.004 17.4 5.6 0.004 17.4 5.6 3.2 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 EGD89413.2 - 0.012 16.0 4.3 0.012 16.0 4.3 2.6 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Zn-ribbon_8 PF09723.10 EGD89413.2 - 3.3 7.9 11.2 3.1 8.0 2.8 2.8 2 0 0 2 2 2 0 Zinc ribbon domain C1_4 PF07975.12 EGD89413.2 - 7.5 6.9 18.1 2.7 8.3 6.9 2.9 2 2 0 2 2 2 0 TFIIH C1-like domain Thymidylat_synt PF00303.19 EGD89414.1 - 1.5e-104 348.9 0.0 1.7e-104 348.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase TGT PF01702.18 EGD89416.1 - 9.4e-145 482.2 0.0 1.1e-144 481.9 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Glyco_hydro_18 PF00704.28 EGD89421.1 - 5e-73 246.6 0.3 7.4e-73 246.0 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EGD89421.1 - 1.5e-11 44.6 18.8 1.5e-11 44.6 18.8 5.6 5 0 0 5 5 5 2 Chitin recognition protein DUF2532 PF10811.8 EGD89421.1 - 0.16 12.0 0.3 0.29 11.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2532) Metallophos PF00149.28 EGD89422.1 - 8.1e-13 49.3 3.4 1.7e-12 48.3 3.4 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ala_racemase_N PF01168.20 EGD89424.1 - 1.2e-21 77.4 0.0 1.5e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.20 EGD89425.2 - 9e-66 222.5 0.3 1.3e-65 222.0 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EGD89425.2 - 4.3e-32 110.6 0.0 9.5e-32 109.5 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EGD89425.2 - 8.2e-17 61.5 0.0 1.8e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Flavi_glycoprot PF00869.20 EGD89425.2 - 0.074 12.3 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains RTP1_C1 PF10363.9 EGD89425.2 - 0.11 12.7 0.1 0.65 10.2 0.1 2.4 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 efThoc1 PF11957.8 EGD89429.2 - 5.3e-99 332.1 7.0 6.8e-99 331.8 7.0 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Aquarius_N PF16399.5 EGD89430.2 - 7.8e-301 999.9 0.0 9.7e-301 999.6 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EGD89430.2 - 2.2e-25 89.5 0.0 3.9e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGD89430.2 - 1.8e-22 80.4 0.0 3.5e-22 79.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGD89430.2 - 3e-07 30.3 0.0 0.00013 21.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGD89430.2 - 2e-06 28.2 0.0 4.2e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EGD89430.2 - 6.7e-06 26.2 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EGD89430.2 - 0.00072 20.0 0.2 0.0036 17.7 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EGD89430.2 - 0.001 19.5 0.0 0.0046 17.4 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EGD89430.2 - 0.0015 18.3 0.1 0.3 10.8 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 EGD89430.2 - 0.0042 16.4 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain PIF1 PF05970.14 EGD89430.2 - 0.0087 15.3 0.0 0.89 8.7 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.21 EGD89430.2 - 0.013 15.0 0.0 0.034 13.7 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EGD89430.2 - 0.014 15.6 1.6 0.54 10.5 0.1 2.8 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 EGD89430.2 - 0.018 15.0 0.0 0.074 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 EGD89430.2 - 0.02 14.7 0.1 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase Adeno_IVa2 PF02456.15 EGD89430.2 - 0.041 12.7 0.0 0.097 11.4 0.0 1.6 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF2075 PF09848.9 EGD89430.2 - 0.068 12.4 1.0 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 EGD89430.2 - 0.077 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain SPOUT_MTase PF02590.17 EGD89430.2 - 0.087 12.8 0.0 4.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase ATPase_2 PF01637.18 EGD89430.2 - 0.15 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EGD89430.2 - 0.19 12.1 0.0 0.86 10.0 0.0 2.2 1 0 0 1 1 1 0 RNA helicase 4HBT PF03061.22 EGD89431.2 - 6.4e-15 55.3 0.1 7.8e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily PBECR2 PF18810.1 EGD89431.2 - 0.026 14.8 0.0 0.032 14.5 0.0 1.1 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 4HBT_3 PF13622.6 EGD89431.2 - 0.057 13.7 0.0 0.067 13.4 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Transp_cyt_pur PF02133.15 EGD89432.1 - 2.2e-92 310.2 37.6 2.3e-92 310.1 35.1 1.8 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Tfb2 PF03849.14 EGD89433.2 - 9.7e-106 353.7 0.0 1.5e-105 353.1 0.0 1.3 2 0 0 2 2 2 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EGD89433.2 - 4.6e-24 84.6 0.6 8.3e-24 83.8 0.6 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EGD89433.2 - 7.9e-06 26.0 0.0 0.00011 22.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhzC-PhzF PF02567.16 EGD89435.1 - 3.2e-39 135.1 0.2 7.7e-39 133.8 0.2 1.6 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein TIMELESS PF04821.14 EGD89436.1 - 6.1e-84 281.6 0.5 2.9e-83 279.3 0.0 2.3 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 EGD89436.1 - 3.1e-39 135.6 26.4 6.5e-38 131.2 16.6 3.7 2 1 0 2 2 2 1 Timeless protein C terminal region 3HCDH_N PF02737.18 EGD89437.1 - 6.5e-52 176.0 0.7 8.6e-52 175.6 0.7 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGD89437.1 - 4e-34 117.1 0.0 8.9e-34 116.0 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGD89437.1 - 7.8e-05 22.9 0.4 0.00022 21.4 0.4 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 EGD89437.1 - 0.00024 21.4 0.1 0.00038 20.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EGD89437.1 - 0.00036 20.2 0.1 0.0088 15.7 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EGD89437.1 - 0.0056 16.3 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 EGD89437.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGD89437.1 - 0.042 13.1 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EGD89437.1 - 0.067 13.2 0.2 0.14 12.1 0.2 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 EGD89437.1 - 0.11 11.8 0.9 1.2 8.5 0.2 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGD89437.1 - 0.16 12.5 2.1 0.62 10.7 2.0 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IBR PF01485.21 EGD89438.2 - 2.6e-06 27.6 35.1 1.4e-05 25.2 9.3 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain ANAPC16 PF17256.2 EGD89438.2 - 1.2 9.6 3.8 18 5.8 0.5 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, subunit 16 Actin PF00022.19 EGD89439.1 - 1.9e-102 342.9 0.0 1.6e-101 339.9 0.0 1.9 1 1 0 1 1 1 1 Actin GCIP PF13324.6 EGD89440.1 - 2.4e-26 92.9 2.6 2.4e-26 92.9 2.6 1.4 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.13 EGD89440.1 - 0.0065 16.4 1.3 0.011 15.6 1.3 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region LRR_8 PF13855.6 EGD89441.1 - 9.4e-32 108.6 37.7 3.6e-09 36.2 2.3 8.1 7 1 1 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 EGD89441.1 - 1.2e-23 82.8 44.5 1e-05 25.8 0.6 10.6 5 3 6 12 12 12 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGD89441.1 - 4.3e-07 29.6 30.5 0.93 10.3 0.0 12.5 12 1 0 12 12 12 1 Leucine Rich Repeat LRR_9 PF14580.6 EGD89441.1 - 0.0014 18.2 17.6 0.089 12.3 0.6 4.6 3 2 1 4 4 4 4 Leucine-rich repeat FANC_SAP PF18081.1 EGD89441.1 - 3.1 8.0 4.7 9.6 6.5 1.7 2.6 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain DUF4686 PF15742.5 EGD89442.1 - 0.031 13.4 9.7 0.042 13.0 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) GrpE PF01025.19 EGD89442.1 - 0.054 13.1 6.7 2.3 7.9 0.3 2.3 2 0 0 2 2 2 0 GrpE TMF_TATA_bd PF12325.8 EGD89442.1 - 0.059 13.6 9.2 0.12 12.6 9.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Mto2_bdg PF12808.7 EGD89442.1 - 0.2 12.0 7.4 0.095 13.0 2.1 2.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Ribosomal_L13e PF01294.18 EGD89443.2 - 9.8e-78 260.1 3.0 1.4e-77 259.6 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Oxidored-like PF09791.9 EGD89445.1 - 2.4e-24 84.7 4.4 5.1e-24 83.7 4.4 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 EGD89445.1 - 0.07 13.1 3.1 0.16 11.9 3.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5522) KAP PF05804.12 EGD89446.2 - 0.0015 16.8 0.0 0.0021 16.3 0.0 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) DPM3 PF08285.11 EGD89447.1 - 2.3e-33 114.2 0.1 2.5e-33 114.1 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2523 PF10734.9 EGD89447.1 - 0.065 13.8 0.1 0.12 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2523) Yip1 PF04893.17 EGD89447.1 - 0.084 12.6 2.2 0.11 12.2 2.2 1.0 1 0 0 1 1 1 0 Yip1 domain Pribosyltran PF00156.27 EGD89448.2 - 5e-06 26.1 0.0 7.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Menin PF05053.13 EGD89451.2 - 2.2 6.6 5.8 2.3 6.5 5.8 1.0 1 0 0 1 1 1 0 Menin DUF3245 PF11595.8 EGD89454.1 - 3.3e-41 141.2 10.2 4.6e-41 140.8 10.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) ATP-grasp_2 PF08442.10 EGD89455.1 - 2.8e-51 174.0 2.1 6.6e-43 146.6 0.3 2.4 1 1 1 2 2 2 2 ATP-grasp domain Ligase_CoA PF00549.19 EGD89455.1 - 8.3e-25 87.4 0.3 1.5e-24 86.5 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EGD89455.1 - 2.2e-06 27.3 0.3 0.00025 20.6 0.0 2.6 2 1 1 3 3 3 2 ATP-grasp domain GARS_A PF01071.19 EGD89455.1 - 9.4e-05 22.3 0.9 0.026 14.3 0.1 2.5 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 EGD89455.1 - 0.0093 15.8 0.3 1.8 8.4 0.1 2.6 1 1 1 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain VID27_N PF17748.1 EGD89455.1 - 0.12 12.2 0.8 0.22 11.3 0.8 1.3 1 0 0 1 1 1 0 VID27 N-terminal region adh_short PF00106.25 EGD89456.1 - 2.8e-38 131.4 0.1 3.6e-38 131.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD89456.1 - 4.6e-27 95.1 0.0 5.9e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EGD89456.1 - 0.0033 16.8 0.0 0.027 13.8 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EGD89456.1 - 0.0041 17.0 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 EGD89456.1 - 0.02 14.9 0.2 0.055 13.5 0.1 1.7 1 1 1 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 EGD89456.1 - 0.16 12.1 0.0 0.39 10.9 0.0 1.7 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NmrA PF05368.13 EGD89456.1 - 0.17 11.5 0.2 0.33 10.5 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family Beta-lactamase PF00144.24 EGD89457.1 - 4.1e-43 147.9 0.0 5.5e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 EGD89457.1 - 0.01 15.5 0.0 4.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 EGD89457.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase SLAC1 PF03595.17 EGD89460.1 - 9.1e-84 281.5 52.1 1.1e-83 281.3 52.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TraP PF07296.11 EGD89460.1 - 0.48 9.6 2.2 0.52 9.5 0.3 1.8 2 0 0 2 2 2 0 TraP protein CAAD PF14159.6 EGD89460.1 - 1.6 8.6 6.7 0.31 10.9 0.4 3.0 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase ABC1 PF03109.16 EGD89461.1 - 8.6e-21 74.3 0.0 2.9e-18 66.2 0.0 2.5 1 1 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EGD89461.1 - 0.053 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Raf1_HTH PF18579.1 EGD89461.1 - 0.19 11.5 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain HA2 PF04408.23 EGD89462.2 - 6.4e-13 48.9 0.0 1.6e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGD89462.2 - 3.1e-07 30.7 0.1 1e-06 29.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EGD89462.2 - 0.025 14.9 0.1 0.059 13.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain SSB PF00436.25 EGD89463.1 - 1.7e-13 50.5 0.0 2.5e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.15 EGD89464.1 - 7.1e-92 307.7 18.4 9.1e-92 307.3 18.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor Pex24p PF06398.11 EGD89464.1 - 0.61 9.0 8.2 0.04 12.9 3.1 1.6 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF4131 PF13567.6 EGD89464.1 - 0.74 9.4 3.5 0.56 9.8 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Bestrophin PF01062.21 EGD89464.1 - 1.2 8.4 5.7 0.42 9.9 1.6 2.1 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel BPD_transp_1 PF00528.22 EGD89464.1 - 3.1 7.5 8.1 5.7 6.6 6.1 2.3 1 1 1 2 2 2 0 Binding-protein-dependent transport system inner membrane component DUF4472 PF14739.6 EGD89465.1 - 0.064 14.0 0.5 0.16 12.7 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Exo_endo_phos PF03372.23 EGD89466.1 - 2.8e-08 33.6 0.0 5.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCP1 PF06058.13 EGD89467.1 - 5.6e-28 97.2 0.0 8.4e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family LIDHydrolase PF10230.9 EGD89468.1 - 2e-72 244.0 0.0 2.3e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 EGD89468.1 - 0.00012 21.5 0.1 0.0009 18.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGD89468.1 - 0.015 15.4 0.0 0.041 14.0 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_6 PF12697.7 EGD89468.1 - 0.018 15.7 0.0 0.026 15.1 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EGD89468.1 - 0.047 13.5 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGD89468.1 - 0.16 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 EGD89468.1 - 0.17 11.7 0.0 0.72 9.7 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) SMK-1 PF04802.15 EGD89469.2 - 1.4e-76 256.6 0.3 2.5e-76 255.8 0.3 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 CDC45 PF02724.14 EGD89469.2 - 2.6 6.3 12.1 3.7 5.7 12.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SPATIAL PF15256.6 EGD89470.1 - 0.15 12.4 3.4 0.16 12.3 3.4 1.1 1 0 0 1 1 1 0 SPATIAL FGF-BP1 PF06473.12 EGD89470.1 - 0.17 11.7 10.0 0.19 11.5 10.0 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) FAM176 PF14851.6 EGD89470.1 - 0.17 11.5 11.1 0.8 9.4 0.7 2.1 1 1 1 2 2 2 0 FAM176 family CDC27 PF09507.10 EGD89470.1 - 0.18 11.1 14.1 0.19 11.0 14.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 EGD89470.1 - 0.21 9.9 7.8 0.21 9.8 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein PPL5 PF18168.1 EGD89470.1 - 0.22 10.8 4.2 0.23 10.7 4.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 AC_N PF16214.5 EGD89470.1 - 0.23 10.5 3.0 0.25 10.4 3.0 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Presenilin PF01080.17 EGD89470.1 - 0.41 9.3 4.6 0.46 9.2 4.6 1.0 1 0 0 1 1 1 0 Presenilin Med19 PF10278.9 EGD89470.1 - 0.89 9.5 19.7 1.2 9.1 19.7 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.12 EGD89470.1 - 1 9.1 11.4 1.1 9.0 11.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 EGD89470.1 - 2.7 7.4 9.7 3.2 7.2 9.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 EGD89470.1 - 3.7 6.2 9.5 4.2 6.1 9.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 V_ATPase_I PF01496.19 EGD89470.1 - 4.3 5.1 6.3 4.9 4.9 6.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LCD1 PF09798.9 EGD89470.1 - 4.5 5.7 6.1 5 5.5 6.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein TFIIE-A_C PF11521.8 EGD89470.1 - 7 7.0 9.5 26 5.2 4.5 2.3 2 1 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha THOC2_N PF16134.5 EGD89470.1 - 7.8 5.0 9.5 9.7 4.7 9.5 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus RAG1_imp_bd PF12560.8 EGD89470.1 - 9.8 5.6 14.4 15 5.0 14.4 1.3 1 1 0 1 1 1 0 RAG1 importin binding SLC35F PF06027.12 EGD89471.1 - 1.8e-97 326.5 23.0 2.1e-97 326.3 23.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EGD89471.1 - 4.8e-10 38.9 1.1 7.2e-10 38.3 1.1 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EGD89471.1 - 2.3e-09 37.5 39.1 4.5e-05 23.6 16.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family FUSC-like PF12805.7 EGD89471.1 - 5.5 6.0 11.4 0.029 13.4 1.2 2.4 3 1 0 3 3 3 0 FUSC-like inner membrane protein yccS NTP_transf_2 PF01909.23 EGD89475.2 - 2.2e-06 27.9 0.0 4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EGD89475.2 - 4.2e-05 23.7 0.0 0.0001 22.4 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 EGD89475.2 - 0.058 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase SE PF08491.10 EGD89476.1 - 9e-94 313.6 0.0 1.1e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EGD89476.1 - 1.1e-10 41.3 0.0 1.8e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EGD89476.1 - 5.5e-09 36.1 0.3 6.2e-06 26.0 0.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGD89476.1 - 1.7e-06 27.4 1.6 4.3e-05 22.8 1.6 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EGD89476.1 - 0.00022 20.6 0.1 0.00045 19.5 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGD89476.1 - 0.00026 21.2 0.6 0.00054 20.1 0.6 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGD89476.1 - 0.00052 19.2 0.1 0.0016 17.6 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EGD89476.1 - 0.00059 19.2 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EGD89476.1 - 0.00072 19.0 1.4 0.001 18.5 1.4 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGD89476.1 - 0.00075 18.7 0.6 0.0013 17.8 0.4 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 EGD89476.1 - 0.001 17.9 0.3 0.0026 16.5 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EGD89476.1 - 0.0018 18.8 0.1 0.018 15.6 0.2 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EGD89476.1 - 0.0068 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 EGD89476.1 - 0.0071 15.2 0.2 0.12 11.2 0.2 2.0 2 0 0 2 2 2 1 Tryptophan halogenase ApbA PF02558.16 EGD89476.1 - 0.0074 15.9 0.3 0.024 14.3 0.3 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.19 EGD89476.1 - 0.12 11.8 0.2 14 4.9 0.1 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 EGD89476.1 - 0.19 10.9 0.1 0.37 10.0 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PPR PF01535.20 EGD89477.1 - 9.8e-07 28.6 0.7 0.07 13.4 0.0 5.6 5 0 0 5 5 5 1 PPR repeat PPR_2 PF13041.6 EGD89477.1 - 0.0057 16.8 0.1 1.9 8.7 0.0 4.2 4 0 0 4 4 4 1 PPR repeat family PPR_1 PF12854.7 EGD89477.1 - 0.009 15.7 0.0 8.5 6.2 0.0 3.4 3 0 0 3 3 3 2 PPR repeat TPR_14 PF13428.6 EGD89477.1 - 0.014 16.2 0.5 2.1 9.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGD89477.1 - 0.024 15.1 0.1 11 6.6 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGD89477.1 - 0.086 13.0 1.1 1.2e+02 3.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat MFS_1 PF07690.16 EGD89478.2 - 2.5e-31 108.9 30.6 2.4e-29 102.4 12.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2269 PF10027.9 EGD89478.2 - 0.8 9.8 8.7 0.59 10.2 4.3 2.8 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) OATP PF03137.20 EGD89478.2 - 1.1 7.4 12.8 0.57 8.4 4.8 3.0 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ferrochelatase PF00762.19 EGD89479.1 - 8.1e-98 327.4 0.0 9.5e-98 327.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Adap_comp_sub PF00928.21 EGD89481.2 - 2.3e-83 279.6 0.0 2.7e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 EGD89481.2 - 0.07 12.6 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Erf4 PF10256.9 EGD89482.1 - 2.4e-41 140.5 0.0 3.6e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Lipase_3 PF01764.25 EGD89483.2 - 0.00074 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.12 EGD89483.2 - 0.017 14.8 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 EGD89483.2 - 0.043 14.4 0.0 0.079 13.5 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 EGD89483.2 - 0.072 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF900 PF05990.12 EGD89483.2 - 0.077 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) zf-C2H2_4 PF13894.6 EGD89484.1 - 4.7e-20 70.5 28.6 0.035 14.9 0.5 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 EGD89484.1 - 4.8e-19 67.7 36.0 0.0011 19.3 1.0 7.3 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EGD89484.1 - 7.8e-14 51.8 28.9 0.0078 16.5 0.5 6.8 2 2 5 7 7 7 5 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EGD89484.1 - 1.2e-12 47.8 34.2 7.2e-07 29.4 0.4 7.3 7 1 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGD89484.1 - 5.6e-12 45.4 27.1 0.043 13.8 0.2 6.5 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGD89484.1 - 4.4e-10 39.6 25.8 2.2e-06 27.8 0.8 6.6 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EGD89484.1 - 7.9e-06 26.1 37.1 0.63 10.6 0.2 7.8 7 1 0 7 7 7 3 Zinc-finger double domain zf-C2H2_11 PF16622.5 EGD89484.1 - 0.00057 19.6 18.6 0.1 12.3 1.8 5.7 7 0 0 7 7 7 2 zinc-finger C2H2-type zf-Di19 PF05605.12 EGD89484.1 - 0.024 14.9 23.8 0.075 13.3 0.1 5.0 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 EGD89484.1 - 0.036 14.2 0.4 0.036 14.2 0.4 5.8 5 2 0 5 5 5 0 Zinc ribbon domain zf_ZIC PF18366.1 EGD89484.1 - 0.19 11.9 9.7 6.4 7.0 0.0 4.3 3 1 1 4 4 4 0 Zic proteins zinc finger domain zf-C2H2_3rep PF18868.1 EGD89484.1 - 1.3 9.7 13.6 2.4 8.8 1.4 3.0 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 EGD89484.1 - 2 8.3 17.8 6.3 6.7 0.1 5.6 6 1 1 7 7 7 0 C2H2 type zinc-finger (1 copy) Cyto_heme_lyase PF01265.17 EGD89485.1 - 8.5e-124 412.9 0.5 9.7e-124 412.7 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase APH PF01636.23 EGD89486.2 - 9.1e-05 22.5 0.1 0.00016 21.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family UQ_con PF00179.26 EGD89488.1 - 7.3e-19 67.8 0.1 1.1e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.23 EGD89489.1 - 1.1e-42 146.7 0.0 1.5e-42 146.3 0.0 1.1 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.17 EGD89490.1 - 1.2e-06 28.3 13.8 0.00013 21.7 8.3 2.3 2 0 0 2 2 2 2 Yip1 domain UFD1 PF03152.14 EGD89494.1 - 7.3e-29 100.4 0.0 3.8e-26 91.6 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 EGD89494.1 - 1.2e-06 28.6 0.1 4.5e-06 26.8 0.1 1.9 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PEX-1N PF09262.11 EGD89494.1 - 0.043 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal zf_C2HC_14 PF18574.1 EGD89494.1 - 6.2 6.7 7.2 2.5 8.0 1.8 2.8 2 0 0 2 2 2 0 C2HC Zing finger domain DPPIV_N PF00930.21 EGD89495.1 - 3.3e-112 374.8 6.5 5.7e-112 374.0 6.5 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EGD89495.1 - 7.9e-39 133.3 2.8 1.4e-38 132.5 2.8 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGD89495.1 - 0.03 14.9 0.1 0.067 13.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGD89495.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S8 PF00082.22 EGD89497.1 - 4.8e-24 85.1 15.0 9.7e-24 84.1 14.9 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGD89497.1 - 6.4e-13 49.2 0.0 1.1e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 MAPEG PF01124.18 EGD89498.1 - 4.1e-11 42.9 2.2 5e-11 42.6 2.2 1.2 1 0 0 1 1 1 1 MAPEG family MARVEL PF01284.23 EGD89499.1 - 3.2e-06 27.2 11.6 6.3e-06 26.3 11.7 1.4 1 1 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.6 EGD89499.1 - 1.5 8.4 13.7 0.24 10.9 8.4 2.0 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF1129 PF06570.11 EGD89499.1 - 1.6 8.2 4.4 3 7.3 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4131 PF13567.6 EGD89499.1 - 2.9 7.5 6.1 5.5 6.6 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RNB PF00773.19 EGD89501.2 - 5.2e-53 180.5 0.0 6.7e-51 173.5 0.0 2.2 1 1 0 1 1 1 1 RNB domain Tom6 PF17112.5 EGD89502.1 - 0.0008 18.9 0.0 0.00094 18.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal CTNNBL PF08216.11 EGD89503.1 - 2e-38 130.7 1.4 6.8e-38 129.0 0.1 2.6 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear PHTB1_C PF14728.6 EGD89503.1 - 0.0096 15.0 0.3 0.018 14.1 0.3 1.4 1 0 0 1 1 1 1 PTHB1 C-terminus Drf_GBD PF06371.13 EGD89503.1 - 0.063 12.8 0.6 0.68 9.5 0.1 2.8 3 0 0 3 3 3 0 Diaphanous GTPase-binding Domain Mo25 PF08569.11 EGD89503.1 - 0.077 12.3 0.8 0.23 10.8 0.9 1.7 1 1 0 1 1 1 0 Mo25-like V-ATPase_H_C PF11698.8 EGD89503.1 - 0.14 12.3 2.8 23 5.1 0.0 3.8 4 1 0 4 4 4 0 V-ATPase subunit H RNA_pol_Rpb2_6 PF00562.28 EGD89504.1 - 3.6e-123 411.5 0.8 4.4e-123 411.2 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGD89504.1 - 9.4e-60 201.6 0.0 2.6e-59 200.2 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EGD89504.1 - 1.9e-47 161.4 0.0 3.2e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EGD89504.1 - 5e-33 113.4 0.0 1.1e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EGD89504.1 - 1.2e-25 89.4 0.1 3.2e-25 88.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EGD89504.1 - 1.4e-24 86.2 0.4 3.7e-24 84.8 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EGD89504.1 - 7.2e-23 80.9 2.0 1.2e-22 80.2 0.4 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 AMPK1_CBM PF16561.5 EGD89506.1 - 5.1e-05 23.4 0.0 8.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF951 PF06107.11 EGD89506.1 - 0.27 11.2 1.3 0.48 10.4 1.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) Nucleopor_Nup85 PF07575.13 EGD89508.1 - 3.5e-21 75.4 0.5 4.2e-16 58.7 0.0 2.8 3 0 0 3 3 3 2 Nup85 Nucleoporin ADH_N PF08240.12 EGD89510.1 - 1.1e-22 80.0 0.4 1.8e-22 79.2 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGD89510.1 - 1.1e-14 54.5 0.0 1.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGD89510.1 - 3.7e-06 28.0 0.0 6.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGD89510.1 - 0.0088 15.4 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3336 PF11815.8 EGD89512.1 - 1.4e-46 157.6 1.3 2.2e-46 157.0 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EGD89512.1 - 4.4e-19 69.5 1.0 2.3e-18 67.1 0.1 2.7 2 1 0 2 2 2 1 Patatin-like phospholipase Ribosomal_S15 PF00312.22 EGD89512.1 - 0.11 12.8 0.4 0.27 11.5 0.4 1.7 1 0 0 1 1 1 0 Ribosomal protein S15 LRR_8 PF13855.6 EGD89514.1 - 1.4e-12 47.1 20.4 1.9e-07 30.8 3.6 4.4 3 1 3 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 EGD89514.1 - 2.8e-12 46.7 5.9 0.00027 21.3 0.1 4.7 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGD89514.1 - 2.7e-07 30.2 7.9 2.2 9.1 0.0 6.9 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 EGD89514.1 - 2.9e-07 30.0 11.3 0.96 9.7 0.1 6.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 EGD89514.1 - 0.044 13.3 0.3 1.1 8.7 0.0 2.3 1 1 1 2 2 2 0 Leucine-rich repeat SART-1 PF03343.13 EGD89514.1 - 0.16 10.5 2.8 0.37 9.3 0.8 2.0 2 0 0 2 2 2 0 SART-1 family Metallophos PF00149.28 EGD89515.2 - 2.8e-40 139.0 0.1 3.6e-40 138.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGD89515.2 - 1.2e-22 80.0 2.6 1.6e-22 79.7 1.7 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain TERT_thumb PF17984.1 EGD89515.2 - 0.068 13.1 0.5 0.12 12.3 0.5 1.3 1 0 0 1 1 1 0 Telomerase reverse transcriptase thumb DNA binding domain Arf PF00025.21 EGD89516.2 - 2.4e-59 199.7 0.0 6.2e-59 198.4 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 EGD89516.2 - 4.5e-09 35.9 0.0 1.6e-05 24.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGD89516.2 - 3.7e-08 33.0 0.0 4.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGD89516.2 - 3.8e-06 27.0 0.0 5.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGD89516.2 - 9.4e-06 25.8 0.0 2.1e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGD89516.2 - 0.00033 20.3 0.0 0.00046 19.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGD89516.2 - 0.0037 16.6 0.0 0.0043 16.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region mRNA_decap_C PF16741.5 EGD89516.2 - 0.13 11.6 0.2 0.77 9.1 0.1 2.0 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus Mannosidase_ig PF17786.1 EGD89517.1 - 0.15 12.7 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 Mannosidase Ig/CBM-like domain DUF2457 PF10446.9 EGD89518.1 - 2e-149 498.7 35.3 2e-149 498.7 35.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) CDC45 PF02724.14 EGD89518.1 - 0.97 7.6 31.8 0.78 8.0 22.0 2.3 2 0 0 2 2 2 0 CDC45-like protein RPOL_N PF14700.6 EGD89518.1 - 1.5 8.1 5.3 0.2 11.0 1.1 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal CH PF00307.31 EGD89519.1 - 7.9e-09 35.7 0.0 0.0002 21.5 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain MID_pPIWI_RE PF18157.1 EGD89519.1 - 0.002 18.4 0.3 0.0098 16.2 0.0 2.3 3 0 0 3 3 3 1 MID domain of pPIWI_RE IQ PF00612.27 EGD89519.1 - 0.01 15.5 1.4 0.03 14.1 1.4 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ank_2 PF12796.7 EGD89520.1 - 6.7e-44 148.4 8.2 9.6e-10 38.9 0.6 5.7 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD89520.1 - 4.7e-25 87.6 2.6 0.00017 22.1 0.1 7.2 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD89520.1 - 3.8e-24 82.1 0.7 0.037 14.6 0.0 10.2 10 1 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 EGD89520.1 - 6.9e-22 77.2 10.8 2.4e-07 30.9 0.7 7.2 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EGD89520.1 - 3e-15 55.9 10.0 0.024 15.1 0.3 8.8 9 0 0 9 9 9 3 Ankyrin repeat F-box-like PF12937.7 EGD89520.1 - 0.0013 18.6 0.1 0.0028 17.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD89520.1 - 0.086 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 F-box domain MIG-14_Wnt-bd PF06664.12 EGD89524.1 - 0.0065 15.7 6.8 0.0065 15.7 6.8 3.2 1 1 1 2 2 2 1 Wnt-binding factor required for Wnt secretion Sec61_beta PF03911.16 EGD89525.2 - 7e-18 64.4 1.0 9.3e-18 64.0 1.0 1.2 1 0 0 1 1 1 1 Sec61beta family Pkinase PF00069.25 EGD89528.1 - 3.6e-28 98.6 0.0 4.7e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD89528.1 - 6.4e-26 91.2 0.0 8.8e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGD89528.1 - 3.6e-05 23.2 0.0 5.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGD89528.1 - 0.0043 16.4 0.0 0.0097 15.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like YukC PF10140.9 EGD89528.1 - 0.0083 15.0 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC RIO1 PF01163.22 EGD89528.1 - 0.0096 15.5 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGD89528.1 - 0.025 14.2 0.5 0.31 10.6 0.7 2.3 1 1 1 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 EGD89528.1 - 0.029 14.3 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGD89528.1 - 0.069 12.2 0.1 0.38 9.8 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 PIP49_C PF12260.8 EGD89528.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 zinc_ribbon_15 PF17032.5 EGD89529.1 - 0.0021 18.7 0.9 0.0031 18.2 0.9 1.2 1 0 0 1 1 1 1 zinc-ribbon family RecR PF02132.15 EGD89529.1 - 0.077 12.6 0.9 1.6 8.4 0.1 2.2 2 0 0 2 2 2 0 RecR protein zf-LITAF-like PF10601.9 EGD89529.1 - 1.9 8.8 8.7 7.3 6.9 0.4 2.2 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Dynein_light PF01221.18 EGD89530.2 - 1.4e-33 115.0 7.3 6.9e-28 96.8 1.3 2.0 1 1 1 2 2 2 2 Dynein light chain type 1 DUF1805 PF08827.11 EGD89530.2 - 0.053 13.9 0.3 0.072 13.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) RRM_1 PF00076.22 EGD89531.2 - 7.5e-42 141.0 0.0 1.3e-15 56.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGD89531.2 - 2.3e-05 24.0 0.0 0.0066 16.0 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGD89531.2 - 0.00053 19.8 0.2 0.14 12.0 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif APG17 PF04108.12 EGD89531.2 - 0.038 13.1 0.1 0.054 12.6 0.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Limkain-b1 PF11608.8 EGD89531.2 - 0.084 13.0 0.1 40 4.4 0.0 3.5 3 1 0 3 3 3 0 Limkain b1 WW_like PF17890.1 EGD89531.2 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Peptidoglycan hydrolase LytB WW-like domain Aldo_ket_red PF00248.21 EGD89532.1 - 1.1e-44 152.8 0.0 1.4e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.22 EGD89533.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GHMP_kinases_C PF08544.13 EGD89533.1 - 0.011 16.0 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal Pkinase PF00069.25 EGD89535.2 - 1.1e-07 31.5 0.0 2.6e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD89535.2 - 0.14 11.4 0.0 0.8 8.9 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase NIF PF03031.18 EGD89537.1 - 1.6e-54 183.9 0.4 2.3e-54 183.4 0.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LRR_4 PF12799.7 EGD89538.1 - 2e-32 110.7 39.3 3.3e-09 36.9 6.4 6.5 1 1 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGD89538.1 - 7.6e-21 73.6 38.6 3.1e-05 23.6 1.3 6.1 3 2 1 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EGD89538.1 - 1e-14 54.4 20.1 3e-07 30.1 3.8 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 EGD89538.1 - 0.00039 20.6 30.4 2.9 8.8 0.9 8.9 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_6 PF13516.6 EGD89538.1 - 0.00055 19.8 28.7 0.17 12.0 0.2 7.1 8 0 0 8 8 8 4 Leucine Rich repeat ABC_membrane_2 PF06472.15 EGD89539.1 - 7.3e-88 294.5 0.1 7.3e-88 294.5 0.1 1.8 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGD89539.1 - 8.6e-18 65.2 0.0 1.6e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 EGD89539.1 - 0.00092 19.8 0.3 0.049 14.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EGD89539.1 - 0.0039 16.9 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 EGD89539.1 - 0.019 15.4 0.5 0.47 10.9 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 EGD89539.1 - 0.031 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 EGD89539.1 - 0.051 13.0 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGD89539.1 - 0.095 13.1 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 EGD89539.1 - 0.1 12.0 0.1 3.6 6.9 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Sigma54_activat PF00158.26 EGD89539.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 EGD89539.1 - 0.18 11.5 0.0 0.47 10.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Clr2 PF10383.9 EGD89540.2 - 1.7e-22 80.8 0.0 3e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 ABC_membrane_2 PF06472.15 EGD89541.2 - 2.5e-87 292.7 0.0 2.8e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 BTB PF00651.31 EGD89542.1 - 9.6e-08 32.2 0.0 1.5e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 EGD89542.1 - 0.001 19.2 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain tRNA-synt_2 PF00152.20 EGD89543.1 - 3.2e-68 230.1 0.0 4.1e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGD89543.1 - 7.9e-10 38.6 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGD89543.1 - 3.4e-05 23.5 0.0 0.016 14.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.15 EGD89544.1 - 9.8e-22 76.4 0.7 9.8e-22 76.4 0.7 1.5 1 1 1 2 2 2 1 Tim10/DDP family zinc finger Tom5 PF10642.9 EGD89544.1 - 0.029 14.4 3.9 0.33 11.0 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase SUIM_assoc PF16619.5 EGD89544.1 - 1.5 9.0 5.0 2.2 8.4 5.0 1.5 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Transcrip_act PF04949.13 EGD89545.1 - 0.086 12.7 3.7 0.18 11.7 3.7 1.5 1 0 0 1 1 1 0 Transcriptional activator Fib_alpha PF08702.10 EGD89545.1 - 0.22 11.7 1.1 0.5 10.5 1.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CLTH PF10607.9 EGD89546.1 - 1.5e-29 102.8 0.0 2.9e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EGD89546.1 - 4.3e-08 33.1 0.7 8.8e-08 32.0 0.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 EGD89546.1 - 0.00093 18.6 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 EGD89546.1 - 0.0058 16.6 0.4 0.011 15.7 0.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGD89546.1 - 0.011 16.1 0.9 0.02 15.2 0.9 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 EGD89546.1 - 0.021 14.7 0.7 0.041 13.7 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGD89546.1 - 0.034 14.0 1.2 0.072 13.0 1.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGD89546.1 - 0.049 13.5 1.1 0.1 12.5 1.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGD89546.1 - 0.049 13.5 1.6 0.1 12.5 1.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SAD_SRA PF02182.17 EGD89547.2 - 5.3e-27 94.4 0.0 8e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain 2OG-FeII_Oxy PF03171.20 EGD89548.1 - 0.00039 20.8 0.0 0.0008 19.9 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PCI PF01399.27 EGD89549.2 - 7.5e-10 39.3 0.0 1.5e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.14 EGD89549.2 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Ribosomal_L18A PF01775.17 EGD89550.1 - 2.2e-54 182.7 1.4 2.6e-54 182.5 1.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF2887 PF11103.8 EGD89550.1 - 0.041 13.9 0.0 0.047 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) NAD_binding_1 PF00175.21 EGD89551.1 - 4.1e-31 107.9 0.0 6.9e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGD89551.1 - 1.1e-23 83.4 0.0 2.1e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGD89551.1 - 2e-08 34.5 0.0 2.5e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HMG_box PF00505.19 EGD89552.2 - 2e-11 44.1 3.0 2e-11 44.1 3.0 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGD89552.2 - 1e-07 32.5 2.6 4.8e-07 30.3 2.6 2.3 1 0 0 1 1 1 1 HMG-box domain Amidohydro_1 PF01979.20 EGD89553.2 - 1.5e-73 248.1 0.2 2.7e-73 247.3 0.2 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EGD89553.2 - 5.7e-54 181.6 1.3 1.1e-53 180.6 1.3 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EGD89553.2 - 1.1e-40 137.6 0.2 8.3e-40 134.8 0.0 2.2 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 EGD89553.2 - 1.1e-37 128.3 0.0 2.2e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 EGD89553.2 - 1.9e-07 30.9 0.1 0.00017 21.2 0.0 2.6 2 1 1 3 3 3 2 Amidohydrolase family DRMBL PF07522.14 EGD89554.2 - 0.00021 21.4 0.1 0.0011 19.1 0.0 2.3 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase NicO PF03824.16 EGD89555.1 - 0.49 9.7 2.3 0.69 9.2 2.3 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein F-box-like PF12937.7 EGD89556.2 - 2.4e-05 24.1 0.0 5.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like UPF0147 PF03685.13 EGD89556.2 - 0.036 14.1 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) NPR2 PF06218.11 EGD89557.2 - 7.1e-80 268.9 0.0 2.1e-79 267.4 0.0 1.7 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Rox3 PF08633.10 EGD89557.2 - 0.15 12.3 0.8 0.53 10.5 1.3 1.6 2 0 0 2 2 2 0 Rox3 mediator complex subunit Ada3 PF10198.9 EGD89558.1 - 6.1e-52 175.3 0.0 6.1e-52 175.3 0.0 1.9 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF572 PF04502.13 EGD89558.1 - 0.0051 16.5 1.8 0.0097 15.6 1.8 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-RING_2 PF13639.6 EGD89559.2 - 3.3e-11 43.3 8.3 8.7e-11 42.0 8.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGD89559.2 - 5e-08 32.6 1.6 5e-08 32.6 1.6 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGD89559.2 - 1.4e-07 31.3 4.8 2.8e-07 30.3 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGD89559.2 - 3.2e-06 27.0 3.1 6.2e-06 26.1 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGD89559.2 - 1.7e-05 24.6 3.7 1.7e-05 24.6 3.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD89559.2 - 4.8e-05 23.3 2.3 4.8e-05 23.3 2.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGD89559.2 - 0.00053 20.2 7.6 0.0028 17.9 7.6 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGD89559.2 - 0.0036 17.3 1.9 0.0078 16.2 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EGD89559.2 - 0.021 14.7 5.3 0.021 14.7 5.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGD89559.2 - 0.27 11.4 6.1 0.69 10.1 6.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EGD89559.2 - 0.78 9.4 3.2 1.8 8.3 3.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FRG1 PF06229.12 EGD89560.1 - 3.7e-52 176.8 0.0 5e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 EGD89560.1 - 0.072 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Fascin domain ADH_N PF08240.12 EGD89561.1 - 4.2e-35 119.9 3.8 6.1e-35 119.4 2.8 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGD89561.1 - 2.7e-16 59.7 0.0 4.4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGD89561.1 - 6.7e-12 45.3 0.0 1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGD89561.1 - 4.5e-06 27.8 0.0 7.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 EGD89561.1 - 0.0069 16.7 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EGD89561.1 - 0.012 16.1 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EGD89561.1 - 0.046 13.0 1.0 0.069 12.4 1.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_3 PF03447.16 EGD89561.1 - 0.11 13.1 0.0 1.1 10.0 0.0 2.3 2 1 1 3 3 3 0 Homoserine dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.9 EGD89561.1 - 1.1 9.4 3.6 0.38 10.9 0.4 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region HECT PF00632.25 EGD89562.1 - 2.9e-68 230.6 0.0 4e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L15e PF00827.17 EGD89563.1 - 7.5e-89 296.5 12.2 9.3e-89 296.2 12.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 FXMRP1_C_core PF12235.8 EGD89563.1 - 3.4 8.3 9.4 0.39 11.3 3.3 2.0 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Kinetochor_Ybp2 PF08568.10 EGD89564.2 - 0.053 12.0 0.3 0.063 11.8 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin WD40 PF00400.32 EGD89565.2 - 1.5e-31 107.9 10.1 1.9e-07 31.6 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD89565.2 - 7.1e-14 51.9 0.0 0.0001 22.5 0.0 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 EGD89566.1 - 3.2e-13 48.2 4.5 3.1e-06 26.3 0.4 3.2 3 0 0 3 3 3 2 EF hand ZZ PF00569.17 EGD89566.1 - 1.2e-11 44.2 4.2 2.1e-11 43.4 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.6 EGD89566.1 - 1.1e-10 41.8 7.2 3.4e-08 33.8 1.7 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGD89566.1 - 3.8e-10 38.9 3.4 0.00018 21.2 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGD89566.1 - 6.5e-07 28.6 1.9 0.0022 17.4 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGD89566.1 - 0.0001 22.1 5.8 0.0063 16.3 0.4 3.3 4 0 0 4 4 4 2 EF-hand domain pair C1_2 PF03107.16 EGD89566.1 - 0.0089 16.3 3.7 0.019 15.3 3.7 1.5 1 0 0 1 1 1 1 C1 domain HemY_N PF07219.13 EGD89566.1 - 0.12 12.6 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 HemY protein N-terminus MFS_1 PF07690.16 EGD89567.2 - 1.6e-50 172.0 69.4 2.3e-49 168.2 48.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD89567.2 - 9.7e-14 51.1 9.9 9.7e-14 51.1 9.9 3.5 4 0 0 4 4 4 2 Sugar (and other) transporter TMEM220 PF15071.6 EGD89567.2 - 6 7.7 7.2 3.6 8.4 3.0 2.9 2 1 0 2 2 2 0 Transmembrane family 220, helix DUF3382 PF11862.8 EGD89567.2 - 7.8 6.9 10.1 1.7 9.0 0.6 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF3382) Peptidase_M24 PF00557.24 EGD89568.2 - 2.1e-47 161.5 0.0 2.6e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EGD89568.2 - 1.6e-19 69.9 5.3 3.3e-19 68.9 5.3 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EGD89568.2 - 0.0021 18.1 6.0 0.0021 18.1 6.0 2.2 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 EGD89568.2 - 1.8 8.5 4.8 4.3 7.3 4.8 1.7 1 0 0 1 1 1 0 HIT zinc finger FAD_binding_3 PF01494.19 EGD89569.2 - 2e-05 24.0 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 EGD89569.2 - 0.015 14.3 0.0 0.03 13.4 0.0 1.5 1 1 1 2 2 2 0 Squalene epoxidase Sugar_tr PF00083.24 EGD89572.1 - 6.9e-83 279.0 21.7 8.1e-83 278.8 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGD89572.1 - 7.8e-13 48.1 40.2 2.7e-10 39.7 14.2 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGD89572.1 - 0.0033 16.4 5.2 0.0033 16.4 5.2 2.3 2 0 0 2 2 2 1 MFS_1 like family Ribosomal_S8 PF00410.19 EGD89573.2 - 2.3e-14 53.4 0.0 3.9e-13 49.5 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein S8 PIP5K PF01504.18 EGD89575.1 - 2.5e-36 125.3 0.8 1.4e-27 96.6 1.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EGD89575.1 - 8.1e-32 110.5 0.0 1.4e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EGD89575.1 - 5.8e-15 55.2 4.1 5.8e-15 55.2 4.1 2.0 2 0 0 2 2 2 1 FYVE zinc finger DZR PF12773.7 EGD89575.1 - 0.32 11.0 6.8 0.18 11.8 2.6 2.5 2 0 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 EGD89575.1 - 2.1 8.3 10.9 0.021 14.7 2.9 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPP1 PF10341.9 EGD89576.1 - 1.9e-17 63.2 0.0 5.3e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD SBDS_C PF09377.10 EGD89579.2 - 6.5 6.8 6.9 0.38 10.8 0.1 2.5 2 1 0 2 2 2 0 SBDS protein C-terminal domain DUF1769 PF08588.10 EGD89580.2 - 1.7e-26 92.2 0.2 2.8e-26 91.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) MTS_N PF08468.11 EGD89580.2 - 0.17 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal Iso_dh PF00180.20 EGD89581.1 - 1.2e-96 323.9 0.0 2.5e-96 322.8 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ICMT PF04140.14 EGD89581.1 - 0.19 12.2 0.0 0.32 11.5 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PK PF00224.21 EGD89583.1 - 8.3e-174 577.4 4.5 1e-173 577.1 4.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGD89583.1 - 1.2e-38 131.9 0.0 5.3e-38 129.9 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGD89583.1 - 0.00016 20.9 0.3 0.00049 19.3 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EGD89583.1 - 0.0039 16.2 0.1 0.042 12.8 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DUF218 PF02698.17 EGD89583.1 - 0.16 12.0 0.0 0.46 10.5 0.0 1.9 1 1 0 1 1 1 0 DUF218 domain SUR7 PF06687.12 EGD89585.1 - 2.6e-41 141.6 2.2 3.2e-41 141.3 2.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Tweety PF04906.13 EGD89585.1 - 0.064 11.9 0.2 0.38 9.4 0.0 2.0 2 0 0 2 2 2 0 Tweety Ribosomal_S17_N PF16205.5 EGD89587.2 - 9e-33 112.5 0.4 1.9e-32 111.5 0.4 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EGD89587.2 - 3.8e-27 94.2 0.3 1.8e-26 92.0 0.4 2.1 2 0 0 2 2 2 1 Ribosomal protein S17 Spc7_N PF15402.6 EGD89588.1 - 0 1057.4 48.1 0 1057.0 48.1 1.1 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 EGD89588.1 - 4.2e-118 393.7 2.7 4.2e-118 393.7 2.7 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein Pil1 PF13805.6 EGD89589.1 - 1.7e-126 421.1 0.1 2.6e-126 420.6 0.1 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 EGD89589.1 - 0.095 12.1 1.3 0.17 11.3 0.6 1.7 1 1 0 2 2 2 0 FAM92 protein XPG_N PF00752.17 EGD89590.1 - 8.8e-35 119.2 0.0 2.2e-34 118.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGD89590.1 - 3.6e-25 88.1 0.0 9.8e-25 86.7 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 EGD89590.1 - 0.00017 22.1 0.0 0.00064 20.3 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 EGD89590.1 - 0.0037 17.6 0.0 0.0092 16.3 0.0 1.6 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family HHH_5 PF14520.6 EGD89590.1 - 0.068 13.8 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain WD40 PF00400.32 EGD89591.2 - 7.6e-16 58.2 12.8 1e-05 26.2 0.3 9.5 9 0 0 9 9 9 4 WD domain, G-beta repeat DUF5554 PF17709.1 EGD89591.2 - 0.019 15.0 0.0 0.059 13.5 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5554) LSM PF01423.22 EGD89592.1 - 9.6e-09 34.8 0.0 1.6e-08 34.1 0.0 1.3 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGD89592.1 - 0.015 15.5 0.0 0.031 14.4 0.0 1.6 1 1 1 2 2 2 0 Ataxin 2 SM domain Metallophos PF00149.28 EGD89594.2 - 1.7e-37 129.9 0.1 2.7e-37 129.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGD89594.2 - 4e-15 56.0 0.0 7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain ANAPC4_WD40 PF12894.7 EGD89595.2 - 3.7e-05 23.9 0.0 0.56 10.5 0.0 3.3 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGD89595.2 - 0.00038 21.2 2.8 0.29 12.1 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat HIRA_B PF09453.10 EGD89595.2 - 0.00044 20.0 0.5 0.0013 18.5 0.5 1.9 1 0 0 1 1 1 1 HIRA B motif Csm1_N PF18504.1 EGD89597.2 - 0.09 13.1 1.1 0.49 10.8 1.1 2.3 1 0 0 1 1 1 0 Csm1 N-terminal domain YabA PF06156.13 EGD89597.2 - 0.36 11.5 1.4 1.1 9.9 1.4 1.9 1 0 0 1 1 1 0 Initiation control protein YabA F-box-like PF12937.7 EGD89598.2 - 0.001 18.9 0.1 0.0027 17.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 EGD89598.2 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Gpr1_Fun34_YaaH PF01184.19 EGD89599.2 - 4.1e-48 163.8 8.8 5.5e-48 163.3 8.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ANTH PF07651.16 EGD89600.2 - 8.9e-10 38.0 0.0 1.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain Memo PF01875.17 EGD89603.2 - 1.2e-41 142.7 0.0 1.8e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Memo-like protein Rad4 PF03835.15 EGD89604.1 - 1.4e-15 57.2 2.9 2.4e-15 56.5 2.9 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EGD89604.1 - 9.4e-14 51.8 0.4 2e-13 50.8 0.4 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily WD40 PF00400.32 EGD89606.1 - 1.4e-10 41.6 14.9 0.09 13.7 0.0 9.4 10 1 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD89606.1 - 8.2e-10 38.9 0.4 0.16 12.3 0.0 6.4 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGD89606.1 - 1.7e-06 27.8 0.2 0.00017 21.3 0.2 2.7 2 0 0 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 EGD89606.1 - 0.0024 16.9 0.0 0.18 10.7 0.0 2.9 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 EGD89606.1 - 0.055 12.7 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Treacle PF03546.14 EGD89606.1 - 0.079 11.8 0.9 0.13 11.1 0.9 1.3 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle PQQ PF01011.21 EGD89606.1 - 0.15 12.0 1.1 42 4.3 0.1 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat Cyclin_N PF00134.23 EGD89608.1 - 8.9e-36 122.4 0.1 8.9e-36 122.4 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGD89608.1 - 2.3e-09 37.4 1.5 1.6e-08 34.7 0.1 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain TMPIT PF07851.13 EGD89608.1 - 0.066 12.5 0.0 0.092 12.0 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Acyl_transf_3 PF01757.22 EGD89610.2 - 0.00055 19.1 11.6 0.0014 17.7 11.7 1.7 1 1 0 1 1 1 1 Acyltransferase family Caps_synth_CapC PF14102.6 EGD89610.2 - 0.045 14.2 0.1 0.045 14.2 0.1 1.9 2 0 0 2 2 2 0 Capsule biosynthesis CapC Pyr_redox_2 PF07992.14 EGD89611.1 - 1.3e-15 57.5 0.0 4.2e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGD89611.1 - 3.4e-05 23.2 0.4 0.0025 17.1 0.4 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGD89611.1 - 0.00028 19.7 0.0 0.0025 16.6 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EGD89611.1 - 0.002 18.3 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGD89611.1 - 0.0065 15.6 0.1 0.63 9.1 0.0 2.3 1 1 1 2 2 2 2 Glucose inhibited division protein A DAO PF01266.24 EGD89611.1 - 0.015 14.9 0.4 0.039 13.5 0.1 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 EGD89611.1 - 0.029 13.6 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 EGD89611.1 - 0.031 13.4 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGD89611.1 - 0.036 14.0 0.9 2.9 7.9 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EGD89611.1 - 0.23 10.7 2.6 0.43 9.8 1.0 2.2 2 1 1 3 3 3 0 FAD binding domain Cytomega_UL20A PF05984.12 EGD89612.1 - 0.018 15.3 0.1 0.039 14.3 0.1 1.5 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein NAPRTase_N PF17767.1 EGD89613.1 - 0.0014 19.0 1.1 0.0027 18.1 1.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain FKBP_C PF00254.28 EGD89614.1 - 1.5e-32 111.7 0.0 1.9e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyt-b5 PF00173.28 EGD89615.1 - 5.8e-17 61.6 0.0 8.2e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Beta-lactamase PF00144.24 EGD89616.1 - 4.1e-27 95.3 0.0 5.3e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Tom37 PF10568.9 EGD89618.2 - 1.5e-37 128.7 0.0 2.8e-37 127.8 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EGD89618.2 - 1.2e-07 31.4 0.0 8.2e-07 28.7 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGD89618.2 - 0.0028 18.4 0.0 0.0093 16.7 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain NOA36 PF06524.12 EGD89621.1 - 4.4 6.5 7.4 6.9 5.9 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein NAPRTase PF04095.16 EGD89622.2 - 8.8e-57 192.5 0.0 2.6e-28 99.3 0.2 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EGD89622.2 - 2.5e-31 108.7 0.4 5.8e-24 84.9 0.0 2.5 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Syntaxin PF00804.25 EGD89623.2 - 5.5e-18 65.4 11.5 5.5e-18 65.4 11.5 1.8 2 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.6 EGD89623.2 - 9.7e-09 35.5 6.5 4e-08 33.5 0.5 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EGD89623.2 - 1.8e-05 24.6 0.9 6.8e-05 22.8 0.3 2.2 2 0 0 2 2 2 1 SNARE domain COG2 PF06148.11 EGD89623.2 - 0.0053 16.8 0.2 0.0053 16.8 0.2 2.7 2 1 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.21 EGD89623.2 - 0.034 14.6 8.5 1.3 9.5 0.0 3.2 3 1 0 3 3 3 0 Spectrin repeat MCU PF04678.13 EGD89623.2 - 0.07 13.2 7.3 0.049 13.7 0.9 2.6 2 1 0 2 2 2 0 Mitochondrial calcium uniporter Baculo_F PF12259.8 EGD89623.2 - 0.1 11.1 3.9 0.18 10.3 0.1 2.2 1 1 1 2 2 2 0 Baculovirus F protein Gp-FAR-1 PF05823.12 EGD89623.2 - 0.1 13.0 3.9 1.6 9.1 2.5 2.3 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CENP-H PF05837.12 EGD89623.2 - 0.11 12.9 8.6 0.83 10.1 0.3 2.6 2 1 1 3 3 3 0 Centromere protein H (CENP-H) PTA_PTB PF01515.19 EGD89623.2 - 0.12 11.6 1.2 0.19 11.0 1.2 1.3 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase Fib_alpha PF08702.10 EGD89623.2 - 0.13 12.5 10.1 1.2 9.4 0.4 3.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family BORCS8 PF10167.9 EGD89623.2 - 0.14 12.1 4.3 0.18 11.8 0.4 2.4 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 MT0933_antitox PF14013.6 EGD89623.2 - 0.18 12.1 0.6 0.69 10.3 0.1 2.2 2 0 0 2 2 2 0 MT0933-like antitoxin protein YtxH PF12732.7 EGD89623.2 - 0.97 10.0 3.0 97 3.6 3.0 2.9 1 1 0 1 1 1 0 YtxH-like protein Gp58 PF07902.11 EGD89623.2 - 1.1 7.5 9.4 1.6 6.9 9.4 1.3 1 1 0 1 1 1 0 gp58-like protein ISG65-75 PF11727.8 EGD89623.2 - 3.4 6.8 8.1 11 5.1 2.7 2.5 2 1 1 3 3 3 0 Invariant surface glycoprotein TMPIT PF07851.13 EGD89623.2 - 6.9 5.8 8.0 6.3 5.9 0.5 2.2 1 1 0 2 2 2 0 TMPIT-like protein BolA PF01722.18 EGD89624.1 - 5.8e-30 103.4 2.3 7.1e-30 103.1 2.3 1.1 1 0 0 1 1 1 1 BolA-like protein RPA_C PF08784.11 EGD89624.1 - 0.0079 16.8 0.2 0.011 16.4 0.1 1.3 1 1 0 1 1 1 1 Replication protein A C terminal AMP-binding PF00501.28 EGD89625.2 - 1.2e-31 109.7 0.0 2.8e-31 108.6 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme IF4E PF01652.18 EGD89626.1 - 2.5e-52 176.9 1.7 3.2e-52 176.5 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.12 EGD89627.2 - 1.8e-17 63.3 1.3 4.9e-16 58.7 0.2 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family Ribosomal_S5 PF00333.20 EGD89628.1 - 1.3e-27 95.6 2.1 9.2e-27 92.8 1.0 2.5 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGD89628.1 - 9.9e-22 76.2 0.0 1.6e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EGD89628.1 - 2.6 8.6 11.0 6.2 7.4 11.0 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Bac_rhodopsin PF01036.18 EGD89630.1 - 6.5e-39 133.8 16.3 7.8e-39 133.5 16.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein YqhR PF11085.8 EGD89630.1 - 0.011 15.6 2.0 0.026 14.4 0.1 2.2 2 0 0 2 2 2 0 Conserved membrane protein YqhR DUF3810 PF12725.7 EGD89630.1 - 0.054 12.8 10.9 0.11 11.8 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Glycos_transf_4 PF00953.21 EGD89630.1 - 1.2 9.1 12.2 0.082 12.9 5.0 2.4 2 1 0 2 2 2 0 Glycosyl transferase family 4 DUF3040 PF11239.8 EGD89630.1 - 7.2 7.0 8.7 7.9 6.8 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF3938 PF13074.6 EGD89630.1 - 8.1 6.8 13.1 0.58 10.4 2.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) tRNA-synt_1 PF00133.22 EGD89631.1 - 3.9e-162 540.6 0.0 5e-162 540.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGD89631.1 - 1.1e-21 77.4 0.4 2.3e-21 76.3 0.4 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGD89631.1 - 1.9e-20 73.0 0.1 3.7e-13 49.0 0.0 4.4 3 2 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGD89631.1 - 0.063 12.6 0.0 4.4 6.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 EGD89631.1 - 0.082 12.4 0.1 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 EGD89631.1 - 3.2 7.7 4.9 7.9 6.5 4.9 1.7 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS UPF0183 PF03676.14 EGD89632.1 - 6.9e-63 213.3 0.0 2.6e-40 138.9 0.0 2.6 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) Rhodanese PF00581.20 EGD89635.2 - 1.3e-17 64.2 0.0 5.7e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain potato_inhibit PF00280.18 EGD89635.2 - 0.097 13.4 0.0 30 5.4 0.0 2.5 2 0 0 2 2 2 0 Potato inhibitor I family NYN_YacP PF05991.11 EGD89636.2 - 0.043 13.7 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 YacP-like NYN domain NTP_transf_5 PF14907.6 EGD89638.1 - 0.027 14.1 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase DUF2007 PF09413.10 EGD89638.1 - 0.033 14.3 0.0 0.82 9.9 0.0 2.3 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein Metallophos PF00149.28 EGD89639.2 - 5.7e-10 40.0 0.7 8.6e-10 39.5 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGD89639.2 - 6.2e-07 29.8 0.1 7.8e-06 26.2 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AbiEii PF08843.11 EGD89640.1 - 0.0057 16.6 0.0 0.0067 16.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system RPEL PF02755.15 EGD89641.1 - 9.1e-28 95.1 2.5 4.2e-08 32.6 0.1 3.4 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.6 EGD89641.1 - 0.0098 16.4 0.3 0.037 14.6 0.1 1.8 1 1 1 2 2 2 1 PPIC-type PPIASE domain Sigma70_r3 PF04539.16 EGD89641.1 - 0.072 13.2 1.6 3.1 8.0 0.5 2.4 2 0 0 2 2 2 0 Sigma-70 region 3 Translin PF01997.16 EGD89642.1 - 6.2e-59 199.4 0.1 8.5e-59 199.0 0.1 1.2 1 0 0 1 1 1 1 Translin family Hemerythrin PF01814.23 EGD89642.1 - 0.099 13.3 0.0 0.29 11.7 0.0 1.9 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain HBM PF16591.5 EGD89642.1 - 0.12 11.8 0.6 14 5.0 0.0 2.6 2 1 0 3 3 3 0 Helical bimodular sensor domain NPV_P10 PF05531.12 EGD89642.1 - 0.52 10.8 2.1 44 4.6 0.0 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mannosyl_trans PF05007.13 EGD89643.2 - 9.1e-63 212.5 5.4 9.1e-63 212.5 5.4 1.5 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EGD89643.2 - 1.5e-12 47.3 1.0 1.5e-12 47.3 1.0 1.8 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EGD89643.2 - 3e-06 27.1 3.5 3e-06 27.1 3.5 2.6 3 0 0 3 3 3 1 Glycosyltransferase family 87 F-box-like PF12937.7 EGD89644.1 - 0.0044 16.9 0.0 0.018 14.9 0.0 2.1 1 1 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 EGD89645.2 - 1.6e-12 47.0 0.0 2.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Miff PF05644.11 EGD89645.2 - 0.065 12.8 2.4 0.11 12.1 2.4 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff TFIIA PF03153.13 EGD89645.2 - 0.36 10.8 7.5 2.2 8.2 7.7 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Dicty_REP PF05086.12 EGD89645.2 - 0.91 7.4 7.4 1.2 7.0 7.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Menin PF05053.13 EGD89645.2 - 7.3 4.8 8.2 12 4.1 8.2 1.3 1 0 0 1 1 1 0 Menin SQS_PSY PF00494.19 EGD89646.2 - 1.5e-34 119.7 0.0 2.7e-34 118.9 0.0 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase DUF4328 PF14219.6 EGD89646.2 - 0.21 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Amidohydro_1 PF01979.20 EGD89647.1 - 3.6e-10 39.7 0.4 1.2e-09 38.0 0.4 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 EGD89647.1 - 4.4e-07 30.0 0.0 6.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase CoA_binding_2 PF13380.6 EGD89647.1 - 0.0053 17.2 0.2 0.15 12.5 0.1 2.7 2 1 0 3 3 3 1 CoA binding domain DnaJ-X PF14308.6 EGD89648.1 - 1.7e-79 266.2 5.7 1.7e-79 266.2 5.7 2.9 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGD89648.1 - 4.1e-25 87.7 0.3 1e-24 86.4 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain Condensin2nSMC PF12422.8 EGD89648.1 - 0.036 14.2 0.2 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit OrfB_IS605 PF01385.19 EGD89648.1 - 0.25 11.6 2.2 0.65 10.2 2.2 1.7 1 0 0 1 1 1 0 Probable transposase IMS PF00817.20 EGD89650.1 - 3.2e-42 144.0 0.4 1.1e-41 142.4 0.3 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 EGD89650.1 - 6.4e-14 52.7 0.2 1.7e-13 51.3 0.2 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EGD89650.1 - 7.1e-05 22.9 0.0 0.00021 21.4 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif NIBRIN_BRCT_II PF16508.5 EGD89651.2 - 4.9e-06 26.9 0.0 9.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein Acetyltransf_1 PF00583.25 EGD89652.1 - 2.2e-08 34.3 0.1 4e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGD89652.1 - 1.3e-07 31.6 0.0 2.7e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGD89652.1 - 9.7e-06 25.9 0.5 1.9e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGD89652.1 - 0.069 13.2 0.0 0.64 10.1 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ferritin_2 PF13668.6 EGD89653.1 - 1.5e-11 44.7 0.1 2.7e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.24 EGD89654.1 - 3.7e-21 75.5 22.6 1.1e-11 44.3 7.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.25 EGD89656.2 - 1.9e-11 43.8 0.0 2.7e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD89656.2 - 5.2e-05 22.6 0.0 0.00014 21.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase AMP-binding PF00501.28 EGD89657.1 - 5.9e-79 265.6 0.0 7.3e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD89657.1 - 4.1e-12 46.9 0.9 9.4e-12 45.8 0.9 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 EGD89658.1 - 3.8e-39 134.6 25.4 3.8e-39 134.6 25.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily CoA_binding_2 PF13380.6 EGD89660.1 - 2.2e-27 95.8 0.0 2.6e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Methyltransf_11 PF08241.12 EGD89662.2 - 1.7e-23 83.0 0.0 2.9e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD89662.2 - 9.2e-22 77.6 0.0 1.9e-21 76.6 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD89662.2 - 2.3e-14 53.4 0.0 3.4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD89662.2 - 2.2e-12 47.6 0.0 6.5e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD89662.2 - 7.3e-10 38.9 0.0 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD89662.2 - 3.3e-09 36.4 0.0 2.9e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGD89662.2 - 2.8e-05 23.7 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EGD89662.2 - 0.00025 21.0 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGD89662.2 - 0.00052 19.5 0.0 0.0008 18.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 EGD89662.2 - 0.0019 17.3 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 EGD89662.2 - 0.0035 17.3 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGD89662.2 - 0.0039 16.5 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 EGD89662.2 - 0.0064 16.1 0.0 0.0099 15.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 EGD89662.2 - 0.01 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 EGD89662.2 - 0.023 14.5 0.0 0.063 13.1 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase TehB PF03848.14 EGD89662.2 - 0.058 12.8 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.6 EGD89662.2 - 0.15 13.1 0.0 0.54 11.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain HIT PF01230.23 EGD89663.1 - 7.5e-23 81.1 0.3 1.3e-22 80.3 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EGD89663.1 - 1e-05 25.9 0.0 2.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGD89663.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 EGD89663.1 - 0.086 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Rad4 PF03835.15 EGD89664.1 - 1.9e-31 108.7 0.1 5.7e-31 107.2 0.1 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EGD89664.1 - 9.3e-29 99.7 0.2 1.9e-28 98.7 0.2 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 EGD89664.1 - 1.5e-16 61.1 1.4 3.3e-16 60.0 0.1 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 EGD89664.1 - 2.4e-14 52.9 0.4 6.8e-14 51.4 0.1 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 EGD89664.1 - 0.00053 20.4 0.0 0.0034 17.8 0.0 2.4 2 0 0 2 2 2 1 Transglutaminase-like superfamily HD_3 PF13023.6 EGD89665.1 - 5.9e-49 166.2 0.1 7e-49 165.9 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EGD89665.1 - 7.2e-13 48.7 0.1 9.2e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EGD89665.1 - 0.0054 16.9 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 HD domain HATPase_c_4 PF13749.6 EGD89665.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.7 2 0 0 2 2 2 0 Putative ATP-dependent DNA helicase recG C-terminal HAUS6_N PF14661.6 EGD89666.2 - 1.1e-10 41.5 0.4 3e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus cobW PF02492.19 EGD89667.2 - 2.2e-28 99.1 0.1 3e-28 98.6 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGD89667.2 - 1.2e-07 31.6 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain CDCA PF18484.1 EGD89667.2 - 0.034 14.0 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat Auxin_BP PF02041.16 EGD89667.2 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein Mob1_phocein PF03637.17 EGD89668.2 - 7.8e-20 71.6 0.0 1.2e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 EGD89668.2 - 0.43 10.9 5.1 0.86 9.9 5.1 1.4 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases DUF4769 PF15992.5 EGD89668.2 - 3.8 7.2 4.9 4.6 7.0 4.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4769) Pkinase PF00069.25 EGD89669.1 - 5.1e-11 42.4 0.0 1.5e-09 37.6 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD89669.1 - 8.5e-10 38.3 0.0 8.7e-09 35.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase BrkDBD PF09607.10 EGD89671.1 - 0.069 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Brinker DNA-binding domain DUF1158 PF06643.11 EGD89671.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1158) Lon_C PF05362.13 EGD89672.1 - 2.1e-63 213.6 0.0 4e-63 212.7 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EGD89672.1 - 4.2e-22 79.0 0.0 1e-21 77.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 EGD89672.1 - 1.5e-10 41.3 0.1 4.4e-10 39.8 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 EGD89672.1 - 4e-07 30.1 0.0 8.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EGD89672.1 - 2.4e-06 27.4 0.0 6.5e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 EGD89672.1 - 2.8e-06 27.5 0.0 7.9e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGD89672.1 - 1.2e-05 25.1 0.7 0.00049 19.9 0.0 3.3 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGD89672.1 - 1.3e-05 25.5 0.0 0.00017 21.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 EGD89672.1 - 1.3e-05 24.3 0.1 5.2e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 PrkA AAA domain AAA_16 PF13191.6 EGD89672.1 - 0.00025 21.5 2.2 0.0013 19.2 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EGD89672.1 - 0.021 14.9 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGD89672.1 - 0.023 14.4 0.0 0.073 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGD89672.1 - 0.025 14.3 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EGD89672.1 - 0.028 14.3 0.2 0.092 12.6 0.0 1.9 2 0 0 2 2 1 0 RsgA GTPase AAA_18 PF13238.6 EGD89672.1 - 0.049 14.2 0.0 0.049 14.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 EGD89672.1 - 0.057 12.9 0.4 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region F-box-like_2 PF13013.6 EGD89672.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain RNA_helicase PF00910.22 EGD89672.1 - 0.062 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EGD89672.1 - 0.074 13.0 0.2 1 9.2 0.0 2.5 1 1 1 2 2 2 0 NTPase SKI PF01202.22 EGD89672.1 - 0.3 11.2 0.0 0.3 11.2 0.0 2.5 3 0 0 3 3 2 0 Shikimate kinase ABC_tran PF00005.27 EGD89672.1 - 0.64 10.5 0.1 0.64 10.5 0.1 2.8 3 0 0 3 3 3 0 ABC transporter DUF445 PF04286.12 EGD89672.1 - 0.73 9.6 8.5 0.54 10.0 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF445) LON_substr_bdg PF02190.16 EGD89673.1 - 1.6e-19 70.6 0.0 2.4e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain DnaJ_C PF01556.18 EGD89674.1 - 1.2e-36 126.1 0.0 1.6e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGD89674.1 - 1.5e-23 82.7 0.6 5.2e-23 80.9 0.4 2.0 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGD89674.1 - 1.1e-09 38.4 21.4 1.1e-09 38.4 21.4 2.2 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.19 EGD89674.1 - 0.24 11.4 8.5 0.08 13.0 1.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 EGD89674.1 - 2.6 8.1 19.7 0.19 11.7 5.2 3.0 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein PTH2 PF01981.16 EGD89675.1 - 0.15 12.4 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 BRO1 PF03097.18 EGD89676.1 - 5.1e-130 433.8 0.4 5.1e-130 433.8 0.4 1.9 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EGD89676.1 - 7.3e-81 271.7 15.4 1.4e-80 270.8 15.4 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF416 PF04222.12 EGD89676.1 - 0.065 12.7 4.9 1.2 8.5 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF416) DUF2383 PF09537.10 EGD89676.1 - 0.5 10.7 7.5 1.5 9.2 0.6 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF2383) Baculo_PEP_C PF04513.12 EGD89676.1 - 9.9 6.2 7.4 0.63 10.1 0.8 2.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SAP30_Sin3_bdg PF13867.6 EGD89677.1 - 2.3e-09 37.4 0.2 7.2e-09 35.9 0.1 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 F-box-like PF12937.7 EGD89678.1 - 2e-05 24.4 0.1 0.00033 20.5 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGD89678.1 - 0.00013 21.7 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGD89678.1 - 0.0039 17.1 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 F-box Zip PF02535.22 EGD89680.1 - 0.056 12.7 7.4 0.077 12.2 7.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.9 EGD89680.1 - 0.48 8.9 8.8 0.65 8.5 8.8 1.3 1 0 0 1 1 1 0 Macoilin family FAM76 PF16046.5 EGD89680.1 - 6.8 6.0 9.7 11 5.3 9.7 1.2 1 0 0 1 1 1 0 FAM76 protein MOSC PF03473.17 EGD89681.1 - 9.6e-20 70.9 0.0 1.4e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EGD89681.1 - 9.8e-09 35.1 0.0 4.8e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Amidase PF01425.21 EGD89682.1 - 1.8e-67 228.3 0.0 2e-66 224.8 0.0 2.0 1 1 0 1 1 1 1 Amidase Rad51 PF08423.11 EGD89683.1 - 1.6e-12 47.3 0.0 9.1e-12 44.8 0.0 2.0 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 EGD89683.1 - 5.8e-05 22.7 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 EGD89683.1 - 0.0001 21.8 0.0 0.0003 20.2 0.0 1.8 1 1 0 1 1 1 1 KaiC PhoH PF02562.16 EGD89683.1 - 0.0002 20.9 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.6 EGD89683.1 - 0.00058 19.5 0.1 0.006 16.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGD89683.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 EGD89683.1 - 0.0042 17.0 0.1 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EGD89683.1 - 0.0097 16.3 1.1 0.016 15.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 EGD89683.1 - 0.014 15.9 0.7 0.036 14.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter RNA12 PF10443.9 EGD89683.1 - 0.019 13.8 1.9 0.061 12.0 0.0 2.1 2 0 0 2 2 2 0 RNA12 protein CbiA PF01656.23 EGD89683.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DnaB_C PF03796.15 EGD89683.1 - 0.09 12.1 0.0 2 7.7 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Zot PF05707.12 EGD89683.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ATP-synt_E PF05680.12 EGD89683.1 - 6.9 7.1 6.8 13 6.2 6.8 1.4 1 0 0 1 1 1 0 ATP synthase E chain FA_desaturase PF00487.24 EGD89686.1 - 3.2e-18 66.5 12.5 3.2e-18 66.5 12.5 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGD89686.1 - 1.5e-17 63.5 0.1 4.1e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF1189 PF06691.11 EGD89686.1 - 0.038 13.5 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Med3 PF11593.8 EGD89686.1 - 1.3 8.1 4.2 2 7.5 4.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_M3 PF01432.20 EGD89687.1 - 8.1e-165 549.5 0.4 1.1e-164 549.1 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M3 BSP_II PF05432.11 EGD89688.1 - 0.0039 16.9 3.8 0.0039 16.9 3.8 1.8 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Eapp_C PF10238.9 EGD89688.1 - 0.051 13.7 1.8 0.62 10.1 0.1 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein CDC45 PF02724.14 EGD89688.1 - 0.078 11.3 2.6 0.12 10.7 2.6 1.2 1 0 0 1 1 1 0 CDC45-like protein YABBY PF04690.13 EGD89688.1 - 0.1 13.2 1.5 9.2 6.8 0.5 2.7 2 1 0 2 2 2 0 YABBY protein DUF4637 PF15470.6 EGD89688.1 - 0.4 10.4 6.5 0.13 12.0 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) PI3K_1B_p101 PF10486.9 EGD89688.1 - 0.4 8.4 3.7 0.66 7.7 3.7 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 EGD89688.1 - 0.58 8.2 4.8 0.68 8.0 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nucleo_P87 PF07267.11 EGD89688.1 - 1.8 7.3 4.6 2.5 6.9 4.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RNA_pol_Rpc4 PF05132.14 EGD89688.1 - 1.8 9.0 5.5 0.33 11.4 0.4 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 PAC1 PF16094.5 EGD89688.1 - 2.2 7.4 4.6 3.3 6.8 4.6 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 FAM176 PF14851.6 EGD89688.1 - 5.6 6.6 8.0 0.64 9.7 3.6 1.7 2 0 0 2 2 2 0 FAM176 family EF-hand_7 PF13499.6 EGD89689.2 - 6e-13 49.0 0.0 1.2e-08 35.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGD89689.2 - 4e-11 43.1 0.0 9.1e-05 22.7 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_6 PF13405.6 EGD89689.2 - 7e-10 38.0 0.2 0.013 15.4 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EGD89689.2 - 9.8e-10 37.3 0.0 0.022 14.3 0.0 4.1 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGD89689.2 - 1.2e-06 28.3 0.1 5e-05 23.1 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 EGD89689.2 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) EF-hand_14 PF17959.1 EGD89689.2 - 0.13 12.6 0.0 14 6.1 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Fungal_trans PF04082.18 EGD89690.2 - 4.9e-64 215.9 0.5 1.1e-63 214.7 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EGD89690.2 - 0.00036 20.8 14.7 0.0053 17.2 3.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EGD89690.2 - 0.012 15.9 1.7 0.037 14.3 1.7 1.9 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 EGD89690.2 - 6.2 8.0 19.9 0.34 11.9 3.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGD89690.2 - 9.2 6.9 10.4 2 9.0 2.7 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Glyco_transf_90 PF05686.12 EGD89691.2 - 6.1e-13 48.4 0.5 1.4e-11 43.9 0.5 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 LSM PF01423.22 EGD89693.2 - 1.5e-07 31.0 0.1 1.9e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGD89693.2 - 0.0011 18.5 0.1 0.0016 18.0 0.1 1.2 1 0 0 1 1 1 1 Hfq protein 5-FTHF_cyc-lig PF01812.20 EGD89694.1 - 5.7e-33 114.3 0.0 1.4e-32 113.1 0.0 1.5 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.9 EGD89695.1 - 1.1e-86 289.7 0.0 1.2e-86 289.5 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal YqeY PF09424.10 EGD89696.1 - 2.5e-21 76.2 6.2 3.1e-21 76.0 6.2 1.1 1 0 0 1 1 1 1 Yqey-like protein Ino80_Iec3 PF14612.6 EGD89696.1 - 0.077 13.7 0.7 0.098 13.3 0.7 1.2 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Nucleoporin_N PF08801.11 EGD89697.2 - 6.7e-87 292.0 0.3 9.9e-87 291.5 0.3 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EGD89697.2 - 1.5e-09 37.1 0.1 3.1e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Fungal_lectin PF07938.12 EGD89697.2 - 0.12 11.8 0.0 0.38 10.1 0.0 1.7 1 1 1 2 2 2 0 Fungal fucose-specific lectin DUF2781 PF10914.8 EGD89698.1 - 2.6e-40 138.2 11.2 3e-40 138.0 11.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) SLAC1 PF03595.17 EGD89698.1 - 0.0045 16.3 3.5 0.0055 16.0 3.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel NAT PF04768.13 EGD89699.2 - 1.4e-50 171.3 0.0 2.2e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Pyr_redox_2 PF07992.14 EGD89700.1 - 1.5e-37 129.4 0.0 2e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGD89700.1 - 1.4e-16 60.8 0.0 4e-12 46.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGD89700.1 - 6.5e-08 32.2 0.0 5.6e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGD89700.1 - 1.4e-06 27.7 0.0 9.5e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGD89700.1 - 3.6e-06 27.1 0.0 0.0033 17.6 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGD89700.1 - 2.1e-05 24.6 0.3 0.032 14.2 0.0 3.8 3 1 1 4 4 4 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EGD89700.1 - 0.00035 19.6 0.0 4.8 5.9 0.0 3.1 3 0 0 3 3 3 3 Tryptophan halogenase Lycopene_cycl PF05834.12 EGD89700.1 - 0.00051 19.2 0.0 0.74 8.8 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 EGD89700.1 - 0.00063 18.6 0.0 0.23 10.1 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 EGD89700.1 - 0.00071 19.3 0.1 2 7.9 0.1 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase TrkA_N PF02254.18 EGD89700.1 - 0.001 19.3 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain DUF1188 PF06690.11 EGD89700.1 - 0.0037 16.9 0.0 0.023 14.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) FAD_binding_3 PF01494.19 EGD89700.1 - 0.0069 15.7 0.0 0.45 9.7 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 EGD89700.1 - 0.027 14.9 0.0 2.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding TPR_12 PF13424.6 EGD89702.1 - 7.2e-36 122.3 17.3 7.9e-12 45.3 1.1 6.9 2 1 7 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.6 EGD89702.1 - 7.7e-26 89.2 3.9 0.00017 21.4 0.1 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGD89702.1 - 1.2e-08 35.3 5.3 0.2 12.2 0.0 6.3 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGD89702.1 - 5.3e-07 29.3 2.3 0.0077 15.6 0.0 2.9 1 1 1 3 3 3 2 MalT-like TPR region TPR_2 PF07719.17 EGD89702.1 - 1.1e-05 25.1 4.8 30 5.1 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGD89702.1 - 1.2e-05 25.8 5.0 0.29 11.8 1.1 6.0 4 2 1 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGD89702.1 - 9.4e-05 22.9 10.4 3.4 8.7 0.1 7.2 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGD89702.1 - 0.00018 21.2 0.1 36 4.4 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGD89702.1 - 0.00027 21.3 15.0 0.17 12.6 0.6 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGD89702.1 - 0.0013 18.6 4.8 28 5.1 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat NACHT PF05729.12 EGD89702.1 - 0.0023 17.9 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 EGD89702.1 - 0.0036 17.3 0.0 0.01 15.7 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EGD89702.1 - 0.004 16.4 0.0 0.01 15.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 EGD89702.1 - 0.027 14.7 0.1 51 4.4 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Arf PF00025.21 EGD89702.1 - 0.03 13.8 0.0 0.16 11.4 0.0 2.0 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.6 EGD89702.1 - 0.039 14.2 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGD89702.1 - 0.07 13.5 0.5 0.73 10.2 0.0 2.8 2 1 0 3 3 3 0 AAA ATPase domain TPR_17 PF13431.6 EGD89702.1 - 0.15 12.5 0.3 1.2e+02 3.5 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat AAA_24 PF13479.6 EGD89702.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_5 PF12688.7 EGD89702.1 - 0.33 11.2 2.2 2.4 8.4 0.1 3.4 5 0 0 5 5 5 0 Tetratrico peptide repeat Arv1 PF04161.13 EGD89703.1 - 2.4e-61 207.5 0.0 7.8e-52 176.5 0.0 2.3 2 0 0 2 2 2 2 Arv1-like family DUF1180 PF06679.12 EGD89703.1 - 1.3 9.4 4.9 2.7 8.4 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Dabb PF07876.12 EGD89705.1 - 1.8e-15 57.3 0.0 1.9e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF3810 PF12725.7 EGD89706.1 - 0.062 12.6 0.1 0.062 12.6 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) Aminotran_3 PF00202.21 EGD89707.1 - 4.8e-82 275.8 0.0 5.8e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III BAR_2 PF10455.9 EGD89708.1 - 2.2e-61 207.6 0.2 3.3e-61 207.0 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EGD89708.1 - 3e-20 72.9 5.7 6.8e-19 68.5 5.7 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EGD89708.1 - 0.0055 16.4 0.5 0.097 12.4 0.0 2.3 2 0 0 2 2 2 1 BAR domain of APPL family ApoLp-III PF07464.11 EGD89708.1 - 0.015 15.3 2.8 0.5 10.5 0.1 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TetR_C_24 PF17932.1 EGD89708.1 - 0.052 13.8 0.2 0.2 11.9 0.1 2.0 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SRP_TPR_like PF17004.5 EGD89708.1 - 0.084 12.9 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Putative TPR-like repeat SPATA19 PF15212.6 EGD89708.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial DUF5594 PF18057.1 EGD89710.2 - 0.01 15.7 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5594) Glyco_hydro_72 PF03198.14 EGD89712.2 - 8.1e-127 422.8 5.0 1.1e-126 422.4 5.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EGD89712.2 - 1.2e-13 51.5 0.0 3.6e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 EGD89712.2 - 0.012 14.7 0.8 0.051 12.7 0.8 2.0 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 EGD89712.2 - 0.095 12.1 0.5 12 5.2 0.1 2.3 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) NAD_binding_2 PF03446.15 EGD89713.2 - 3e-25 89.3 0.1 7.1e-25 88.0 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGD89713.2 - 3e-11 43.6 0.5 5.1e-11 42.9 0.5 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 EGD89713.2 - 3.1e-06 27.3 0.2 8.4e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EGD89713.2 - 1.4e-05 25.6 0.2 7.4e-05 23.3 0.1 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 EGD89713.2 - 0.086 12.8 0.4 5.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase F-box-like PF12937.7 EGD89714.2 - 0.00019 21.3 1.1 0.0005 19.9 1.1 1.8 1 0 0 1 1 1 1 F-box-like Abhydrolase_6 PF12697.7 EGD89715.1 - 3.1e-14 54.1 0.2 4.2e-14 53.7 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGD89715.1 - 8.6e-12 45.2 0.0 4.5e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD89715.1 - 2.7e-11 43.2 0.0 3.7e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGD89715.1 - 0.0022 17.8 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 EGD89715.1 - 0.0023 18.1 0.0 0.0047 17.1 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Peptidase_S28 PF05577.12 EGD89715.1 - 0.01 14.7 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Thioredoxin PF00085.20 EGD89718.1 - 6.5e-56 186.7 0.0 3.8e-28 97.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EGD89718.1 - 1.9e-24 86.4 0.9 8.5e-24 84.3 0.2 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EGD89718.1 - 2e-13 50.7 0.0 8.8e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EGD89718.1 - 8.7e-13 48.3 0.0 7.3e-06 25.5 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGD89718.1 - 4.8e-08 33.1 0.0 0.0008 19.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EGD89718.1 - 6.5e-07 29.6 0.0 0.11 12.9 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 EGD89718.1 - 7.5e-06 25.9 0.0 0.031 14.2 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 EGD89718.1 - 0.00018 21.4 0.0 0.1 12.4 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EGD89718.1 - 0.0004 20.1 0.0 0.48 10.2 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 EGD89718.1 - 0.0048 16.8 0.0 0.44 10.4 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 EGD89718.1 - 0.018 15.0 0.0 0.33 10.9 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.6 EGD89718.1 - 0.028 14.6 0.2 3.8 7.6 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin Glutaredoxin PF00462.24 EGD89718.1 - 0.059 13.6 0.1 14 6.0 0.2 2.9 2 1 0 2 2 2 0 Glutaredoxin HSBP1 PF06825.12 EGD89719.1 - 3.6e-20 71.6 2.2 4.4e-20 71.3 2.2 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 EGD89719.1 - 0.0001 22.6 1.7 0.00013 22.3 1.7 1.1 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Matrilin_ccoil PF10393.9 EGD89719.1 - 0.00018 21.3 0.6 0.0014 18.4 0.6 2.1 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.12 EGD89719.1 - 0.0011 19.4 1.3 0.0014 19.0 1.3 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 EGD89719.1 - 0.0048 16.9 0.6 0.0056 16.7 0.6 1.1 1 0 0 1 1 1 1 Laminin Domain II DUF3235 PF11574.8 EGD89719.1 - 0.0079 17.0 0.5 0.0098 16.7 0.5 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3235) Baculo_PEP_C PF04513.12 EGD89719.1 - 0.012 15.7 1.2 0.014 15.4 1.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BORCS6 PF10157.9 EGD89719.1 - 0.026 14.8 0.3 0.028 14.7 0.3 1.2 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Med9 PF07544.13 EGD89719.1 - 0.047 13.8 0.9 0.097 12.8 0.9 1.6 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF3450 PF11932.8 EGD89719.1 - 0.047 13.0 2.6 0.049 12.9 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fzo_mitofusin PF04799.13 EGD89719.1 - 0.069 12.7 1.0 0.073 12.6 1.0 1.1 1 0 0 1 1 1 0 fzo-like conserved region Ebp2 PF05890.12 EGD89720.1 - 4.9e-94 314.8 15.7 4.9e-94 314.8 15.7 2.3 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Caldesmon PF02029.15 EGD89720.1 - 0.0049 15.7 45.7 0.0068 15.2 45.7 1.1 1 0 0 1 1 1 1 Caldesmon BUD22 PF09073.10 EGD89720.1 - 0.76 9.1 54.5 0.032 13.6 33.9 2.1 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 EGD89720.1 - 4.1 5.5 55.4 0.018 13.3 36.5 2.2 2 0 0 2 2 2 0 Nop14-like family Neuregulin PF02158.15 EGD89721.1 - 0.0029 17.0 4.6 0.0047 16.3 4.6 1.2 1 0 0 1 1 1 1 Neuregulin intracellular region E3_UbLigase_EDD PF11547.8 EGD89721.1 - 0.01 15.5 1.0 0.03 14.0 1.0 1.8 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD RNase_T PF00929.24 EGD89721.1 - 0.023 15.3 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 Exonuclease DNMT1-RFD PF12047.8 EGD89721.1 - 0.023 14.7 1.6 0.06 13.4 0.0 2.4 3 0 0 3 3 3 0 Cytosine specific DNA methyltransferase replication foci domain Drc1-Sld2 PF11719.8 EGD89721.1 - 7.2 6.0 16.0 0.6 9.6 11.1 1.5 1 1 0 2 2 2 0 DNA replication and checkpoint protein TruB_N PF01509.18 EGD89722.1 - 9.5e-44 149.4 0.0 3.2e-43 147.7 0.0 1.8 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EGD89722.1 - 9e-07 29.0 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain OHCU_decarbox PF09349.10 EGD89724.2 - 9.5e-28 97.6 0.3 1.1e-27 97.4 0.3 1.1 1 0 0 1 1 1 1 OHCU decarboxylase DUF3684 PF12449.8 EGD89724.2 - 0.024 12.5 0.0 0.035 11.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3684) CorA PF01544.18 EGD89724.2 - 0.1 11.9 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein WD40 PF00400.32 EGD89725.2 - 2.9e-17 62.7 2.3 0.0055 17.5 0.2 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EGD89725.2 - 0.0065 15.0 0.0 0.27 9.7 0.0 2.0 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 EGD89725.2 - 0.033 12.8 0.3 1.5 7.4 0.4 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 CBM_19 PF03427.13 EGD89725.2 - 0.035 14.1 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) ANAPC4_WD40 PF12894.7 EGD89725.2 - 0.043 14.1 0.0 25 5.2 0.0 3.9 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGD89725.2 - 0.075 13.1 0.0 10 6.2 0.0 3.4 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nudix_N_2 PF14803.6 EGD89725.2 - 0.95 9.4 4.6 11 6.0 5.7 2.1 2 0 0 2 2 2 0 Nudix N-terminal SRP9-21 PF05486.12 EGD89726.1 - 1.1e-33 115.5 1.5 1.4e-33 115.2 1.5 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Med3 PF11593.8 EGD89726.1 - 5.4 6.1 6.5 0.32 10.2 1.8 1.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal SKG6 PF08693.10 EGD89729.2 - 0.059 12.8 0.4 0.1 12.0 0.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ribonuc_red_sm PF00268.21 EGD89732.1 - 8.1e-122 406.0 2.0 9.7e-122 405.8 2.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Mito_carr PF00153.27 EGD89733.1 - 1.5e-51 172.3 3.8 9.1e-17 60.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 EGD89734.1 - 5.1e-13 49.3 1.4 0.0002 22.1 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD89734.1 - 7.2e-06 26.2 0.0 0.0037 17.5 0.0 3.6 1 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TruB_C PF09142.11 EGD89734.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Frtz PF11768.8 EGD89734.1 - 0.24 9.7 0.0 0.44 8.8 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1308 PF07000.11 EGD89735.1 - 2.2e-14 53.7 0.0 1.3e-13 51.2 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF2408 PF10303.9 EGD89735.1 - 0.12 12.9 1.2 0.33 11.5 0.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Lung_7-TM_R PF06814.13 EGD89736.1 - 1e-72 244.9 19.7 1.2e-72 244.6 19.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SurA_N_3 PF13624.6 EGD89736.1 - 3.5 7.4 4.6 2.5 7.9 0.2 2.3 2 0 0 2 2 2 0 SurA N-terminal domain CTU2 PF10288.9 EGD89737.2 - 1.2e-10 41.7 0.4 4.1e-10 39.9 0.4 1.8 1 1 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 DUF4112 PF13430.6 EGD89738.1 - 4.8e-36 123.2 0.3 6.4e-36 122.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) AgrD PF05931.11 EGD89738.1 - 0.093 12.8 0.3 0.17 11.9 0.3 1.4 1 0 0 1 1 1 0 Staphylococcal AgrD protein DCP2 PF05026.13 EGD89739.1 - 3.8e-31 107.2 1.4 6.9e-31 106.4 1.4 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EGD89739.1 - 6.4e-17 61.8 0.1 1.2e-16 60.9 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Retrotrans_gag PF03732.17 EGD89741.2 - 0.097 13.0 2.6 1.3 9.4 0.4 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein GCV_T PF01571.21 EGD89742.1 - 0.00013 21.4 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Mei4 PF13971.6 EGD89743.1 - 0.0003 20.4 0.1 0.00053 19.6 0.1 1.5 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 DnaJ PF00226.31 EGD89744.1 - 8.8e-20 70.6 0.1 3.3e-19 68.8 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.22 EGD89744.1 - 0.0087 15.9 0.2 0.025 14.4 0.2 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIG-L PF02585.17 EGD89746.1 - 5.5e-29 101.4 0.0 8.4e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.7 EGD89747.1 - 6e-27 93.8 0.0 1.2e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.6 EGD89747.1 - 1.5e-07 31.4 0.0 5e-06 26.5 0.0 2.5 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 EGD89747.1 - 2.5e-05 24.4 0.1 0.097 12.9 0.1 3.3 4 0 0 4 4 4 2 PPR repeat family Csc2 PF18320.1 EGD89747.1 - 0.003 16.6 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Csc2 Crispr FCD PF07729.12 EGD89747.1 - 0.0076 16.7 0.5 0.016 15.6 0.5 1.5 1 0 0 1 1 1 1 FCD domain PPR PF01535.20 EGD89747.1 - 0.088 13.1 0.2 8.7 6.8 0.1 3.4 3 0 0 3 3 3 0 PPR repeat LSM PF01423.22 EGD89748.2 - 4.2e-13 48.8 0.2 5.9e-13 48.3 0.2 1.4 1 1 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EGD89748.2 - 0.016 15.3 0.1 0.027 14.6 0.1 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain GTP_EFTU PF00009.27 EGD89749.2 - 1.9e-19 70.0 0.1 7.2e-19 68.1 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGD89749.2 - 3.9e-07 30.4 1.4 2.6e-06 27.7 0.9 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EGD89749.2 - 3.4e-05 24.1 0.0 9.4e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EGD89749.2 - 0.0027 17.8 0.1 0.0075 16.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGD89749.2 - 0.0042 17.0 0.1 3.3 7.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 EGD89749.2 - 0.0049 16.6 0.3 2.5 7.9 0.0 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.18 EGD89749.2 - 0.022 14.1 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 EGD89749.2 - 0.037 14.1 3.1 0.22 11.6 0.5 2.5 2 1 0 2 2 2 0 Dynamin family Roc PF08477.13 EGD89749.2 - 0.04 14.2 0.3 0.62 10.3 0.1 2.5 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Lyase_1 PF00206.20 EGD89751.2 - 2.3e-22 79.8 0.1 3.7e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EGD89751.2 - 3.1e-17 62.9 0.0 9.3e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus eIF-5_eIF-2B PF01873.17 EGD89754.1 - 6.3e-41 138.9 0.1 1.2e-40 138.1 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zf-HYPF PF07503.12 EGD89754.1 - 0.35 10.7 2.8 12 5.8 0.0 2.7 3 0 0 3 3 3 0 HypF finger Vfa1 PF08432.10 EGD89754.1 - 0.42 10.9 7.4 0.68 10.2 7.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2894 PF11445.8 EGD89754.1 - 0.48 10.9 5.3 8.9 6.7 5.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) Arc_trans_TRASH PF08394.10 EGD89754.1 - 1.2 9.6 7.4 1.1 9.6 0.3 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain AIM24 PF01987.17 EGD89755.2 - 2.3e-33 115.7 0.2 3e-33 115.3 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 bZIP_1 PF00170.21 EGD89758.1 - 3.5e-06 27.0 4.6 7.6e-06 25.9 4.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor LPP PF04728.13 EGD89758.1 - 0.15 12.4 0.1 0.34 11.3 0.1 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Ras PF00071.22 EGD89759.1 - 1.1e-40 138.9 0.0 1.5e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD89759.1 - 1e-28 99.9 0.0 1.5e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD89759.1 - 6.9e-12 45.2 0.0 2.7e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGD89759.1 - 0.0001 21.7 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGD89759.1 - 0.00022 21.3 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGD89759.1 - 0.0034 16.9 0.0 0.018 14.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGD89759.1 - 0.004 17.1 0.0 0.041 13.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EGD89759.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 EGD89759.1 - 0.011 15.7 0.1 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 EGD89759.1 - 0.023 14.9 0.0 0.05 13.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 EGD89759.1 - 0.024 15.1 0.0 0.044 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EGD89759.1 - 0.025 15.0 0.2 0.14 12.5 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EGD89759.1 - 0.035 13.8 0.0 0.92 9.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EGD89759.1 - 0.15 11.8 0.0 0.46 10.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGD89759.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGD89759.1 - 0.2 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ADH_N PF08240.12 EGD89760.1 - 1.5e-32 111.7 2.1 3.1e-32 110.7 0.3 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGD89760.1 - 3.5e-23 82.0 0.1 6.8e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGD89760.1 - 7.8e-07 28.8 0.1 2.1e-06 27.4 0.1 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGD89760.1 - 0.0007 20.7 0.0 0.0018 19.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGD89760.1 - 0.0027 17.0 0.2 0.0045 16.3 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EGD89760.1 - 0.0057 16.3 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FtsJ PF01728.19 EGD89760.1 - 0.022 14.9 0.0 0.037 14.1 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EGD89760.1 - 0.031 15.0 0.0 0.072 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 EGD89760.1 - 0.035 13.3 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGD89760.1 - 0.07 11.8 0.2 0.1 11.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein PrmA PF06325.13 EGD89760.1 - 0.086 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AdoHcyase_NAD PF00670.21 EGD89760.1 - 0.13 12.3 0.3 0.76 9.8 0.2 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_31 PF13847.6 EGD89760.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mannosidase_ig PF17786.1 EGD89761.2 - 1.3e-16 60.9 0.0 2.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_C PF02836.17 EGD89761.2 - 3.4e-05 23.1 1.0 0.0002 20.6 1.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 EGD89761.2 - 0.00069 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain FAD-oxidase_C PF02913.19 EGD89762.2 - 3.3e-52 177.6 0.1 5.8e-52 176.8 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGD89762.2 - 2.2e-35 121.4 0.0 3.8e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DUF2828 PF11443.8 EGD89763.1 - 8.8e-234 777.3 1.2 1.1e-233 777.0 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) KR PF08659.10 EGD89763.1 - 0.15 11.9 0.5 0.38 10.6 0.1 1.8 2 0 0 2 2 2 0 KR domain Het-C PF07217.11 EGD89764.2 - 8.2e-118 394.4 0.1 1e-117 394.1 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C TraT PF05818.12 EGD89764.2 - 8 6.1 5.8 25 4.4 5.8 1.8 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Clr5 PF14420.6 EGD89765.1 - 4.4e-21 74.8 0.7 4.4e-21 74.8 0.7 2.3 2 0 0 2 2 2 1 Clr5 domain Ribosomal_L30_N PF08079.12 EGD89765.1 - 5.2 7.4 8.7 34 4.8 4.9 2.8 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain Phytase-like PF13449.6 EGD89767.1 - 1.6e-40 139.9 0.1 2.1e-40 139.5 0.1 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase Coatomer_WDAD PF04053.14 EGD89769.2 - 1.9e-141 472.1 0.1 2.9e-141 471.6 0.1 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EGD89769.2 - 8e-103 344.3 0.5 8.1e-102 341.0 0.5 2.0 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EGD89769.2 - 4.7e-33 112.7 22.2 1.7e-07 31.8 0.3 8.0 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD89769.2 - 2.6e-07 30.8 0.1 0.022 15.1 0.0 5.1 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EGD89769.2 - 0.003 17.4 0.1 0.35 10.8 0.0 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS Nup160 PF11715.8 EGD89769.2 - 0.021 13.5 6.0 1.5 7.3 0.4 3.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Evr1_Alr PF04777.13 EGD89770.1 - 2.6e-29 101.6 3.3 5.8e-29 100.5 3.3 1.6 1 0 0 1 1 1 1 Erv1 / Alr family Bd3614-deam PF14439.6 EGD89770.1 - 0.048 13.7 0.1 5.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Bd3614-like deaminase DEK_C PF08766.11 EGD89771.2 - 0.0028 17.6 0.3 0.0055 16.6 0.1 1.6 2 0 0 2 2 2 1 DEK C terminal domain Adaptin_N PF01602.20 EGD89772.2 - 5.3e-135 450.9 2.4 6.7e-135 450.6 2.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGD89772.2 - 1.2e-64 217.3 3.0 9.1e-62 207.9 0.4 3.0 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGD89772.2 - 1.5e-17 63.8 1.7 5.1e-07 30.0 0.0 5.1 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 EGD89772.2 - 3.7e-13 48.5 1.3 0.013 15.6 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EGD89772.2 - 4.6e-05 23.8 0.4 0.59 10.7 0.0 5.4 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 EGD89772.2 - 0.0015 18.1 0.3 1.6 8.3 0.0 3.6 3 1 1 4 4 4 1 CLASP N terminal Arm PF00514.23 EGD89772.2 - 0.0036 17.3 4.8 7.6 6.7 0.0 6.1 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EGD89772.2 - 0.01 16.0 0.1 2.1 8.6 0.0 3.8 2 2 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 EGD89772.2 - 0.032 14.3 0.2 5.6 7.1 0.0 3.7 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain TLD PF07534.16 EGD89773.2 - 4.3e-07 30.2 0.0 1.3e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 TLD VID27 PF08553.10 EGD89774.1 - 3.7e-194 644.7 0.0 5e-194 644.2 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EGD89774.1 - 2.8e-75 251.9 0.2 2.8e-75 251.9 0.2 3.3 3 1 1 4 4 4 1 VID27 N-terminal region VID27_PH PF17747.1 EGD89774.1 - 1.8e-47 160.1 0.7 8.1e-47 158.0 0.3 2.1 2 0 0 2 2 2 1 VID27 PH-like domain JHY PF15261.6 EGD89774.1 - 0.52 11.0 3.5 0.71 10.6 1.1 2.4 2 0 0 2 2 2 0 Jhy protein PRP38_assoc PF12871.7 EGD89774.1 - 0.59 10.8 11.1 2 9.1 11.1 1.9 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term GRIM-19 PF06212.12 EGD89776.2 - 1.1e-10 41.6 0.1 4.1e-10 39.7 0.1 1.8 1 1 0 1 1 1 1 GRIM-19 protein Xpo1 PF08389.12 EGD89777.1 - 1.2e-12 48.2 6.2 1.5e-10 41.3 3.2 4.2 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 EGD89777.1 - 0.0027 17.6 1.2 0.073 13.0 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Glyco_hydro_5_C PF18564.1 EGD89778.1 - 9e-23 80.6 0.0 2.1e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EGD89778.1 - 1.2e-08 34.7 3.1 2.2e-06 27.3 1.1 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) EKLF_TAD1 PF16832.5 EGD89778.1 - 0.024 14.5 0.2 0.06 13.2 0.2 1.6 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Glyco_hydro_42 PF02449.15 EGD89778.1 - 0.053 12.8 0.2 7.7 5.7 0.1 2.1 2 0 0 2 2 2 0 Beta-galactosidase TPR_17 PF13431.6 EGD89779.1 - 5.9e-22 76.4 8.9 0.068 13.6 0.0 13.0 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGD89779.1 - 1.7e-20 71.4 40.8 0.032 14.3 0.1 15.2 17 0 0 17 17 16 7 Tetratricopeptide repeat TPR_16 PF13432.6 EGD89779.1 - 1.8e-18 66.9 27.5 0.02 15.6 0.1 11.7 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGD89779.1 - 1.8e-18 65.5 31.3 0.21 11.5 0.1 13.2 14 2 1 15 15 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGD89779.1 - 2.7e-17 62.0 17.9 0.12 13.3 0.0 14.3 11 5 6 17 17 15 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGD89779.1 - 5.2e-16 58.9 13.4 2.1e-05 24.9 0.0 9.8 9 2 2 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGD89779.1 - 1.9e-15 56.9 33.2 0.055 13.8 0.1 13.2 10 5 4 15 15 15 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGD89779.1 - 2.4e-13 49.5 20.6 0.037 13.7 0.0 10.2 11 1 1 12 12 12 3 TPR repeat TPR_8 PF13181.6 EGD89779.1 - 3.8e-13 48.5 25.8 0.13 12.5 0.2 11.7 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGD89779.1 - 1.3e-08 34.3 11.3 1 9.5 0.0 9.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGD89779.1 - 5.2e-05 23.6 22.9 0.33 11.7 0.1 11.6 14 0 0 14 14 13 1 Tetratricopeptide repeat DUF2225 PF09986.9 EGD89779.1 - 0.015 15.0 1.0 3.7 7.2 0.3 2.8 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF3465 PF11948.8 EGD89779.1 - 0.036 14.0 0.1 0.71 9.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3465) TPR_22 PF18833.1 EGD89779.1 - 0.073 13.2 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EGD89779.1 - 0.074 12.4 0.1 1.1 8.6 0.0 3.0 4 0 0 4 4 4 0 Coatomer epsilon subunit ANAPC5 PF12862.7 EGD89779.1 - 0.076 13.1 4.6 2.2 8.4 0.1 4.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 NPCBM_assoc PF10633.9 EGD89779.1 - 0.13 12.5 0.1 0.32 11.3 0.1 1.6 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase TPR_4 PF07721.14 EGD89779.1 - 0.74 10.6 8.7 5.9e+02 1.6 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat BTAD PF03704.17 EGD89779.1 - 8.8 6.8 11.2 12 6.4 0.2 5.0 6 1 1 7 7 6 0 Bacterial transcriptional activator domain RMI1_N PF08585.12 EGD89780.1 - 2.4e-62 210.6 0.0 2.7e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Vps51 PF08700.11 EGD89781.1 - 1.1e-23 83.1 0.0 2e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 EGD89781.1 - 0.0013 18.9 0.1 0.0024 18.0 0.1 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 EGD89781.1 - 0.04 12.6 0.1 0.05 12.3 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family WD40 PF00400.32 EGD89782.2 - 0.00093 20.0 0.0 0.81 10.7 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat CSN8_PSD8_EIF3K PF10075.9 EGD89783.1 - 2.4e-20 73.0 0.0 5e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EGD89783.1 - 0.0069 15.8 0.0 0.0093 15.4 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family DUF2306 PF10067.9 EGD89784.2 - 6.2e-12 45.9 10.1 1.3e-11 44.9 10.1 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) Pro-kuma_activ PF09286.11 EGD89785.1 - 6.9e-35 120.4 0.0 1.7e-34 119.2 0.0 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGD89785.1 - 2.1e-08 33.8 0.0 7.8e-08 31.9 0.0 1.8 1 1 1 2 2 2 1 Subtilase family adh_short PF00106.25 EGD89786.1 - 2.1e-21 76.3 0.2 2.9e-21 75.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD89786.1 - 2.2e-15 56.9 0.1 2.9e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD89786.1 - 3e-05 24.0 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_16 PF10294.9 EGD89787.2 - 4.4e-14 52.6 0.0 6.3e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EGD89787.2 - 3e-05 24.6 0.0 5.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGD89787.2 - 0.00047 19.7 0.0 0.00063 19.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGD89787.2 - 0.0048 16.5 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGD89787.2 - 0.0074 17.0 0.0 0.014 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGD89787.2 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Met_10 PF02475.16 EGD89787.2 - 0.015 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.6 EGD89787.2 - 0.029 14.2 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 EGD89787.2 - 0.037 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 EGD89787.2 - 0.06 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 EGD89787.2 - 0.11 13.2 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EGD89787.2 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_S24e PF01282.19 EGD89788.1 - 4.3e-33 113.1 0.1 7.5e-33 112.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Pro_isomerase PF00160.21 EGD89790.1 - 3e-33 115.3 0.0 4.7e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EGD89790.1 - 3.4e-16 58.8 0.3 4.9e-15 55.1 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGD89790.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif UDPGP PF01704.18 EGD89791.1 - 1.2e-57 195.4 0.0 1.6e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EGD89791.1 - 0.027 14.8 0.0 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fer4_20 PF14691.6 EGD89791.1 - 0.069 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster MPDZ_u10 PF16667.5 EGD89791.1 - 0.075 13.9 1.3 0.3 12.0 0.5 2.4 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein RPAP1_N PF08621.10 EGD89791.1 - 0.087 12.6 1.2 0.42 10.4 0.0 2.4 2 0 0 2 2 2 0 RPAP1-like, N-terminal zf-CCHC PF00098.23 EGD89792.2 - 2.4e-41 138.0 57.0 2.4e-07 30.5 0.9 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EGD89792.2 - 4.1e-09 36.0 40.4 0.19 11.5 1.1 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 EGD89792.2 - 7.5e-05 22.6 39.4 0.043 13.8 0.0 6.9 4 2 2 6 6 6 4 Zinc knuckle zf-CCHC_5 PF14787.6 EGD89792.2 - 0.021 14.5 0.9 0.021 14.5 0.9 7.0 4 2 3 7 7 7 0 GAG-polyprotein viral zinc-finger Rad51 PF08423.11 EGD89793.2 - 2.3e-62 210.5 0.1 2.5e-62 210.4 0.1 1.0 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EGD89793.2 - 3e-06 26.9 0.0 3.4e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EGD89793.2 - 0.0034 17.0 0.0 0.0042 16.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain DnaB_bind PF10410.9 EGD89793.2 - 0.012 15.8 0.0 0.86 9.8 0.0 2.6 1 1 1 2 2 2 0 DnaB-helicase binding domain of primase AAA_24 PF13479.6 EGD89793.2 - 0.019 14.7 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain RRM_Rrp7 PF17799.1 EGD89794.1 - 3.3e-30 105.0 0.0 5.1e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 EGD89794.1 - 9.6e-28 96.7 6.3 9.6e-28 96.7 6.3 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain LisH PF08513.11 EGD89799.2 - 4.8e-05 23.1 0.1 9.1e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 LisH TRAPP PF04051.16 EGD89801.1 - 3.6e-35 120.8 0.0 4.5e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 EGD89801.1 - 0.0036 16.2 0.0 0.0039 16.1 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A WD40 PF00400.32 EGD89802.2 - 5.1e-13 49.3 0.7 7.7e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD89802.2 - 0.012 15.9 0.0 0.047 14.0 0.0 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain FTCD_N PF07837.12 EGD89802.2 - 0.2 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain DUF3382 PF11862.8 EGD89803.2 - 0.023 15.0 0.3 0.046 14.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Cadherin_C_2 PF16492.5 EGD89803.2 - 0.21 12.3 0.6 2 9.2 0.0 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Glyco_hydro_47 PF01532.20 EGD89804.2 - 1.1e-28 100.4 0.0 1.5e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Mg_chelatase PF01078.21 EGD89804.2 - 0.18 11.1 0.0 0.26 10.7 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Pribosyltran PF00156.27 EGD89806.1 - 5.4e-15 55.2 0.0 8e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGD89806.1 - 0.02 14.3 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HD PF01966.22 EGD89808.1 - 0.0017 18.5 0.1 0.0032 17.7 0.1 1.4 1 0 0 1 1 1 1 HD domain Trp_DMAT PF11991.8 EGD89812.2 - 4.8e-62 210.5 0.0 5.9e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase FAD_binding_4 PF01565.23 EGD89813.2 - 1.7e-22 79.7 1.1 3.2e-22 78.8 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGD89813.2 - 3e-10 40.0 0.3 7e-10 38.8 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF3135 PF11333.8 EGD89813.2 - 0.067 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Methyltransf_33 PF10017.9 EGD89814.2 - 6.5e-80 268.6 0.0 7.9e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DUF4363 PF14276.6 EGD89814.2 - 0.12 12.5 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) adh_short_C2 PF13561.6 EGD89815.1 - 1.8e-41 142.2 0.0 2.3e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD89815.1 - 8.2e-40 136.3 0.0 1.1e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD89815.1 - 5.6e-13 49.2 0.2 1e-12 48.4 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGD89815.1 - 3.4e-05 23.4 0.0 0.00015 21.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGD89815.1 - 0.0036 16.5 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF4332 PF14229.6 EGD89815.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) GDP_Man_Dehyd PF16363.5 EGD89815.1 - 0.063 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Catalase PF00199.19 EGD89816.2 - 2.7e-112 375.7 0.0 3.4e-112 375.4 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGD89816.2 - 1.2e-05 25.4 0.0 2.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Lumazine_bd_2 PF12893.7 EGD89817.1 - 1.3e-26 93.6 0.0 1.5e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 Putative lumazine-binding DUF4878 PF12870.7 EGD89817.1 - 0.0023 18.2 0.2 0.018 15.3 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4878) NmrA PF05368.13 EGD89818.1 - 9.2e-13 48.3 0.0 1.2e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGD89818.1 - 4e-11 43.1 0.0 6.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EGD89818.1 - 3.7e-05 24.0 0.1 5.7e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EGD89818.1 - 4.8e-05 22.9 0.0 0.021 14.3 0.0 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EGD89818.1 - 0.00019 21.7 0.1 0.0003 21.0 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain PglD_N PF17836.1 EGD89818.1 - 0.034 14.8 0.0 0.069 13.8 0.0 1.5 1 0 0 1 1 1 0 PglD N-terminal domain GDP_Man_Dehyd PF16363.5 EGD89818.1 - 0.15 11.5 0.0 11 5.3 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase LpxI_N PF17930.1 EGD89818.1 - 0.2 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain Ribonuc_L-PSP PF01042.21 EGD89819.2 - 4.1e-40 136.6 0.0 4.9e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP C2 PF00168.30 EGD89820.2 - 1.4e-13 51.0 0.0 3.6e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 EGD89820.2 - 3e-08 32.7 0.1 4.9e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) NDUF_B8 PF05821.11 EGD89821.1 - 2.5e-06 27.5 0.0 2.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 EGD89822.1 - 2.5e-63 213.9 0.7 4.1e-63 213.2 0.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGD89822.1 - 2.9e-20 72.7 0.0 1.5e-19 70.4 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.13 EGD89822.1 - 1.7e-09 37.9 7.2 7.1e-09 35.9 7.2 2.2 1 0 0 1 1 1 1 HSA ResIII PF04851.15 EGD89822.1 - 1.1e-08 35.3 0.0 2.6e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGD89822.1 - 3.8e-05 23.5 0.0 0.00049 19.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2486 PF10667.9 EGD89822.1 - 2.4 8.3 14.9 0.012 15.8 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) ADH_zinc_N PF00107.26 EGD89827.2 - 7.5e-28 97.1 0.4 1.1e-27 96.5 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGD89827.2 - 1.8e-10 42.0 0.0 3.7e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGD89827.2 - 4.6e-06 26.5 0.0 1.4e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EGD89827.2 - 0.064 12.7 0.1 0.091 12.2 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase ADH_N_2 PF16884.5 EGD89827.2 - 0.13 12.1 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Pep_deformylase PF01327.21 EGD89827.2 - 0.24 11.0 0.1 0.49 10.0 0.1 1.4 1 0 0 1 1 1 0 Polypeptide deformylase GRP PF07172.11 EGD89828.1 - 0.0017 19.0 16.4 0.0017 19.0 16.4 2.2 1 1 1 2 2 2 1 Glycine rich protein family zf-Mss51 PF13824.6 EGD89829.1 - 2.4e-27 94.8 7.1 5.4e-27 93.7 7.1 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 EGD89829.1 - 0.0047 17.0 2.0 0.0047 17.0 2.0 2.1 2 0 0 2 2 2 1 MYND finger Oxysterol_BP PF01237.18 EGD89830.1 - 1.4e-136 455.2 0.0 4.1e-136 453.7 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 EGD89830.1 - 4.4e-17 61.9 0.1 4.8e-10 39.5 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGD89830.1 - 1.3e-16 61.0 0.0 7.7e-08 32.8 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EGD89830.1 - 1e-12 47.9 0.1 0.0018 18.6 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EGD89830.1 - 7e-12 44.4 0.1 0.00081 19.7 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat PH PF00169.29 EGD89830.1 - 1e-10 42.1 0.3 2.6e-10 40.8 0.3 1.8 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 EGD89830.1 - 8.7e-09 35.8 0.1 0.0006 20.3 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PH_8 PF15409.6 EGD89830.1 - 4.9e-07 29.9 0.8 1.4e-06 28.5 0.8 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EGD89830.1 - 1.2e-05 25.7 1.8 4.7e-05 23.8 1.8 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain LLC1 PF14945.6 EGD89830.1 - 0.014 16.0 0.8 0.014 16.0 0.8 2.4 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Glyco_tranf_2_3 PF13641.6 EGD89834.1 - 7.8e-30 104.5 0.0 1e-29 104.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGD89834.1 - 4.4e-07 29.9 0.0 7.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGD89834.1 - 2e-06 27.4 0.0 0.0019 17.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 EGD89834.1 - 0.0018 18.2 2.1 0.0018 18.2 2.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 SH3_1 PF00018.28 EGD89836.1 - 1.9e-14 53.0 0.0 2.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGD89836.1 - 1.5e-12 47.2 0.0 4.7e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EGD89836.1 - 1.2e-07 31.3 0.0 2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MBF1 PF08523.10 EGD89838.1 - 1.1e-26 93.1 0.4 1.1e-26 93.1 0.4 1.7 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EGD89838.1 - 8.2e-12 45.0 0.1 1.9e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EGD89838.1 - 2.1e-07 31.2 0.3 7.1e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Iso_dh PF00180.20 EGD89839.1 - 4.4e-70 236.6 0.0 5.4e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.16 EGD89840.1 - 1.2e-16 60.6 36.8 3.5e-15 55.8 18.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrome-c551 PF10643.9 EGD89840.1 - 0.4 10.2 3.3 10 5.7 0.0 2.8 3 0 0 3 3 3 0 Photosystem P840 reaction-centre cytochrome c-551 FTHFS PF01268.19 EGD89841.1 - 2.1e-252 838.3 0.0 4.1e-252 837.3 0.0 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EGD89841.1 - 1.1e-66 223.0 0.6 1.1e-66 223.0 0.6 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EGD89841.1 - 6e-36 123.2 0.2 1.3e-35 122.2 0.2 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 EGD89841.1 - 0.018 14.0 0.4 0.043 12.8 0.1 1.7 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family WD40 PF00400.32 EGD89842.1 - 1.7e-25 88.8 0.6 5.9e-07 30.1 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD89842.1 - 1.3e-13 51.0 0.1 0.0065 16.7 0.0 5.1 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD89842.1 - 0.0021 16.8 0.8 0.073 11.7 0.1 2.5 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Gmad1 PF10647.9 EGD89842.1 - 0.024 14.4 0.0 0.092 12.5 0.0 1.9 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.6 EGD89842.1 - 0.1 12.1 0.2 0.24 11.0 0.2 1.8 1 1 0 1 1 1 0 PQQ-like domain Pkinase PF00069.25 EGD89843.1 - 1.2e-10 41.2 0.0 4.4e-10 39.4 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD89843.1 - 1.4e-06 27.8 0.0 2.3e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGD89843.1 - 0.024 14.6 0.1 0.29 11.0 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGD89843.1 - 0.061 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGD89843.1 - 0.19 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase SDA1 PF05285.12 EGD89844.1 - 1.3 8.4 7.6 1.9 7.8 7.6 1.3 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 EGD89844.1 - 3.7 7.2 9.5 6 6.5 9.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RrnaAD PF00398.20 EGD89845.1 - 0.0074 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DEAD PF00270.29 EGD89848.1 - 1.1e-16 61.1 0.3 5.1e-16 58.9 0.1 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD89848.1 - 5.6e-09 36.3 0.0 2.2e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD89848.1 - 4.5e-07 30.0 0.0 9.8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4332 PF14229.6 EGD89848.1 - 0.092 13.0 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Vps53_N PF04100.12 EGD89849.1 - 4.5e-107 358.3 9.9 9.1e-107 357.3 9.9 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 EGD89849.1 - 7.2e-08 32.1 6.8 1.3e-07 31.2 6.8 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EGD89849.1 - 7.3e-05 22.7 0.1 0.0012 18.7 0.0 2.6 1 1 1 2 2 2 1 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.11 EGD89849.1 - 0.0032 17.5 3.8 0.0095 16.0 2.4 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sporozoite_P67 PF05642.11 EGD89849.1 - 0.1 10.7 5.2 0.15 10.1 5.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Plk4_PB2 PF18409.1 EGD89849.1 - 0.17 12.6 6.0 2.5 8.8 0.6 4.2 2 1 2 4 4 4 0 Polo-like Kinase 4 Polo Box 2 TRPM_tetra PF16519.5 EGD89849.1 - 0.39 10.8 5.9 0.08 13.0 1.8 2.0 2 0 0 2 2 2 0 Tetramerisation domain of TRPM COG5 PF10392.9 EGD89849.1 - 0.65 10.2 7.8 0.42 10.8 3.3 3.0 3 0 0 3 3 3 0 Golgi transport complex subunit 5 GIT1_C PF12205.8 EGD89849.1 - 0.99 9.5 8.5 1 9.5 1.1 2.7 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF5339 PF17274.2 EGD89849.1 - 6.7 7.7 9.9 1 10.3 0.7 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5339) TAP_C PF03943.13 EGD89850.1 - 2.3e-17 62.3 0.7 4.7e-17 61.4 0.7 1.6 1 0 0 1 1 1 1 TAP C-terminal domain RRM_9 PF18444.1 EGD89850.1 - 2.6e-06 27.2 0.0 1.6e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif LRR_9 PF14580.6 EGD89850.1 - 5.6e-06 26.0 0.0 8.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.20 EGD89850.1 - 3.9e-05 24.2 0.0 9.4e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 EGD89850.1 - 9.4e-05 22.7 5.9 0.0043 17.4 0.3 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGD89850.1 - 0.0081 15.9 0.2 0.021 14.6 0.2 1.8 1 0 0 1 1 1 1 Leucine rich repeat COPIIcoated_ERV PF07970.12 EGD89851.1 - 6.7e-80 268.1 0.0 1.1e-79 267.4 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGD89851.1 - 1.4e-29 102.2 0.0 4.6e-29 100.6 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PH PF00169.29 EGD89852.1 - 2.7e-06 27.8 0.0 1.6e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 PH domain zf-C2H2 PF00096.26 EGD89853.2 - 1.1e-24 85.4 55.9 0.00073 19.9 0.7 11.2 11 1 1 12 12 12 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD89853.2 - 1.3e-17 63.0 55.1 0.015 16.1 0.7 10.6 11 0 0 11 11 11 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGD89853.2 - 5.7e-11 42.3 55.4 0.0031 17.8 0.2 10.9 11 1 1 12 12 12 6 Zinc-finger double domain FOXP-CC PF16159.5 EGD89853.2 - 2.2e-05 25.0 28.1 0.15 12.7 0.3 7.7 6 2 2 8 8 8 3 FOXP coiled-coil domain GAGA PF09237.11 EGD89853.2 - 0.00024 20.8 2.9 0.00026 20.7 0.5 2.2 2 0 0 2 2 2 1 GAGA factor zf-C2H2_jaz PF12171.8 EGD89853.2 - 0.00066 19.9 13.0 2.5 8.5 0.0 7.6 9 0 0 9 9 9 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 EGD89853.2 - 0.00094 19.4 16.0 0.15 12.4 1.4 4.1 2 1 1 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 EGD89853.2 - 0.013 15.2 20.1 4.3 7.2 0.0 6.2 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 EGD89853.2 - 0.083 13.6 14.2 6 7.6 0.2 5.2 4 3 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats DUF5472 PF17566.2 EGD89853.2 - 0.16 12.0 3.7 16 5.5 0.1 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5472) CHORD PF04968.12 EGD89853.2 - 0.21 12.3 15.5 3.2 8.5 1.0 4.7 3 1 1 4 4 4 0 CHORD zf-C2H2_aberr PF17017.5 EGD89853.2 - 0.95 9.6 12.6 9.1 6.4 0.6 4.6 3 1 2 5 5 5 0 Aberrant zinc-finger zf-C2H2_9 PF16293.5 EGD89853.2 - 1.8 8.5 6.0 4.8 7.1 0.7 3.3 3 0 0 3 3 2 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 EGD89853.2 - 6.5 7.3 12.7 70 4.0 0.0 6.5 7 0 0 7 7 7 0 Zinc-finger of C2H2 type RNA_pol_Rpb6 PF01192.22 EGD89854.1 - 6.2e-17 61.3 0.1 8.8e-17 60.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pkinase PF00069.25 EGD89855.2 - 9.7e-16 57.9 0.0 9.7e-16 57.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD89855.2 - 4.2e-15 55.7 0.0 4.6e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD89855.2 - 0.00012 21.5 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like MFS_1 PF07690.16 EGD89856.1 - 4.6e-22 78.4 53.1 2.7e-17 62.7 37.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 EGD89857.1 - 8.3e-12 45.4 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGD89857.1 - 3.5e-09 36.7 0.0 5.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD89857.1 - 1.2e-06 28.4 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGD89857.1 - 3.3e-06 27.4 0.0 4.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGD89857.1 - 0.00048 20.2 0.1 0.00069 19.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGD89857.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CENP-Q PF13094.6 EGD89858.1 - 0.045 13.9 0.6 0.49 10.6 0.1 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Phage_NinH PF06322.11 EGD89858.1 - 0.067 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Phage NinH protein Lectin_N PF03954.14 EGD89858.1 - 0.77 9.5 3.5 5.6 6.7 1.2 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain PCI PF01399.27 EGD89859.1 - 3.2e-12 46.9 0.6 1.4e-10 41.6 0.0 3.1 2 0 0 2 2 2 1 PCI domain BAH PF01426.18 EGD89859.1 - 0.0021 17.9 0.1 0.0065 16.3 0.1 1.9 1 1 0 1 1 1 1 BAH domain Pro_Al_protease PF02983.14 EGD89859.1 - 0.05 13.7 0.0 0.35 11.0 0.0 2.6 1 0 0 1 1 1 0 Alpha-lytic protease prodomain G-gamma PF00631.22 EGD89860.1 - 5.7e-21 74.3 0.0 6.5e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 GGL domain Rdx PF10262.9 EGD89861.1 - 2.9e-32 110.7 0.0 3.8e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Rdx family Ribosomal_60s PF00428.19 EGD89864.2 - 1.2e-13 51.5 0.8 1.9e-13 50.8 0.8 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4246 PF14033.6 EGD89864.2 - 0.13 11.3 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) WD40 PF00400.32 EGD89865.1 - 0.04 14.8 4.2 0.75 10.8 0.9 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat URO-D PF01208.17 EGD89866.1 - 4.3e-129 430.6 0.0 4.8e-129 430.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DnaJ_C PF01556.18 EGD89867.1 - 5.8e-39 133.5 0.0 7.7e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGD89867.1 - 1e-24 86.4 2.5 1.7e-24 85.7 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGD89867.1 - 9.3e-15 54.7 18.6 1.6e-14 54.0 18.6 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EGD89867.1 - 1.2 9.1 10.0 1.5 8.8 2.3 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sulfate_transp PF00916.20 EGD89870.2 - 1.5e-44 152.3 2.0 2.3e-44 151.7 2.0 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGD89870.2 - 3.8e-07 29.7 0.0 6.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGD89870.2 - 0.063 13.7 7.6 0.049 14.0 3.3 2.6 2 1 1 3 3 3 0 Molybdate transporter of MFS superfamily SNN_transmemb PF09049.10 EGD89870.2 - 0.77 9.8 2.7 0.59 10.1 0.2 2.2 2 0 0 2 2 2 0 Stannin transmembrane Rab5ip PF07019.12 EGD89872.1 - 1.9e-22 79.6 3.2 2.5e-22 79.3 3.2 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF5084 PF16894.5 EGD89872.1 - 0.47 10.9 4.9 0.64 10.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5084) RPA43_OB PF17875.1 EGD89873.1 - 9.3e-41 139.3 0.0 9.3e-41 139.3 0.0 3.2 3 0 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EGD89873.1 - 0.001 19.4 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DnaJ PF00226.31 EGD89874.1 - 9.7e-13 48.0 0.0 2.7e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain INO80_Ies4 PF08193.11 EGD89875.1 - 3e-68 230.4 33.7 3e-68 230.4 33.7 1.6 1 1 1 2 2 2 1 INO80 complex subunit Ies4 Na_trans_assoc PF06512.13 EGD89875.1 - 0.0055 17.0 2.9 0.0055 17.0 2.9 1.8 2 0 0 2 2 2 1 Sodium ion transport-associated FGF-BP1 PF06473.12 EGD89875.1 - 0.61 9.9 12.6 0.077 12.8 7.0 2.0 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) CPSF100_C PF13299.6 EGD89875.1 - 2.5 8.2 10.0 0.44 10.7 3.9 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Connexin PF00029.19 EGD89875.1 - 3 7.6 3.4 4.7 6.9 3.4 1.3 1 0 0 1 1 1 0 Connexin VIR_N PF15912.5 EGD89875.1 - 7.2 6.1 20.2 6.4 6.3 10.5 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal PTPRCAP PF15713.5 EGD89875.1 - 8.1 6.7 17.0 1.5 9.1 7.6 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RR_TM4-6 PF06459.12 EGD89875.1 - 9.3 6.0 14.5 6.8 6.4 12.6 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CLTH PF10607.9 EGD89876.2 - 2.8e-27 95.4 0.0 5.3e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EGD89876.2 - 2.3e-24 85.8 0.2 3.8e-24 85.1 0.2 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 EGD89876.2 - 0.0036 17.2 0.5 0.0091 15.9 0.1 1.9 2 0 0 2 2 2 1 LisH TPR_2 PF07719.17 EGD89877.2 - 1e-09 37.7 5.3 0.12 12.5 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGD89877.2 - 3e-08 33.2 0.8 0.066 13.1 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGD89877.2 - 4.3e-08 33.3 5.2 0.001 19.3 0.0 4.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGD89877.2 - 7.3e-07 28.8 2.5 0.92 9.7 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGD89877.2 - 1.3e-05 25.0 0.8 5.6 7.4 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGD89877.2 - 0.009 15.9 0.4 2 8.4 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGD89877.2 - 0.013 16.1 9.1 9.3 7.1 0.6 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGD89877.2 - 0.12 12.8 0.0 3.7 8.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_16 PF00722.21 EGD89878.1 - 2.5e-10 40.1 0.1 4.1e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 IDO PF01231.18 EGD89880.1 - 2.6e-34 118.8 0.0 4.8e-34 117.9 0.0 1.4 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase TPR_2 PF07719.17 EGD89881.1 - 9.3e-09 34.7 7.6 0.041 14.0 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat F-box PF00646.33 EGD89881.1 - 8.6e-06 25.5 0.0 2.7e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 F-box domain TPR_12 PF13424.6 EGD89881.1 - 9.2e-06 25.9 6.9 0.004 17.4 0.4 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGD89881.1 - 9.4e-05 22.1 5.6 0.21 11.4 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.7 EGD89881.1 - 0.0018 18.1 0.0 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like TPR_16 PF13432.6 EGD89881.1 - 0.0019 18.8 7.4 0.094 13.4 3.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 EGD89881.1 - 0.014 15.4 2.3 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 EGD89881.1 - 0.092 12.8 5.9 3.4 7.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGD89881.1 - 0.1 13.4 10.4 1.1 10.3 0.9 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGD89881.1 - 0.41 11.2 6.0 3.2 8.3 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGD89881.1 - 0.58 10.1 4.4 3.9 7.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGD89881.1 - 0.59 10.3 6.0 2.5 8.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGD89881.1 - 1.1 9.7 4.9 26 5.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGD89881.1 - 1.3 9.1 4.6 3.8 7.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGD89881.1 - 3.2 8.6 7.7 5.1 7.9 2.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.6 EGD89881.1 - 8.1 6.3 9.0 3.9 7.3 0.0 4.1 4 1 1 5 5 4 0 Leucine rich repeat Glucosamine_iso PF01182.20 EGD89883.1 - 2.9e-69 233.4 0.0 3.3e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAM76 PF16046.5 EGD89884.1 - 0.16 11.3 3.3 0.32 10.3 3.3 1.3 1 0 0 1 1 1 0 FAM76 protein ECH_1 PF00378.20 EGD89884.1 - 0.25 10.6 0.8 0.45 9.8 0.8 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase WD40 PF00400.32 EGD89885.2 - 2.2e-12 47.3 7.4 0.00053 20.7 0.6 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Nop14 PF04147.12 EGD89885.2 - 6.5 4.8 17.4 11 4.1 17.4 1.3 1 0 0 1 1 1 0 Nop14-like family SET PF00856.28 EGD89886.1 - 2.3e-09 37.9 0.0 6e-08 33.3 0.0 2.8 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 EGD89886.1 - 0.031 14.4 7.4 0.089 12.9 7.4 1.9 1 0 0 1 1 1 0 MYND finger RabGAP-TBC PF00566.18 EGD89889.2 - 1.3e-31 110.0 0.0 7.5e-31 107.5 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Mucin PF01456.17 EGD89889.2 - 2.1 8.3 8.6 5.4 7.0 8.6 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein EF-hand_6 PF13405.6 EGD89890.2 - 1e-06 28.1 0.1 1.8e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EGD89890.2 - 4.6e-06 25.8 0.1 6.9e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGD89890.2 - 0.001 19.4 0.1 0.0015 18.9 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGD89890.2 - 0.0016 17.9 0.1 0.0033 16.9 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EGD89890.2 - 0.013 15.3 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain pair SPA PF08616.10 EGD89891.2 - 2.9e-37 127.1 0.0 4.5e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EGD89891.2 - 0.00094 18.0 0.0 0.12 11.1 0.0 2.7 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.9 EGD89891.2 - 0.13 11.8 0.0 0.32 10.6 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Formyl_trans_N PF00551.19 EGD89892.1 - 1.2e-38 132.7 0.0 1.4e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Ribosomal_L7Ae PF01248.26 EGD89893.1 - 1.6e-24 85.5 0.0 1.8e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_1 PF00076.22 EGD89898.2 - 3.1e-18 65.3 0.0 3e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGD89898.2 - 0.00014 21.9 0.1 0.0056 16.7 0.2 2.4 2 0 0 2 2 2 1 Limkain b1 SLD3 PF08639.10 EGD89898.2 - 7.1 5.3 6.3 11 4.7 6.3 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 MA3 PF02847.17 EGD89901.1 - 5.9e-26 90.7 0.2 1.4e-25 89.4 0.1 1.7 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EGD89901.1 - 5.4e-12 45.8 0.1 1.1e-11 44.9 0.1 1.5 1 0 0 1 1 1 1 MIF4G domain DPM2 PF07297.12 EGD89902.2 - 2.3e-31 107.9 1.4 2.6e-31 107.7 1.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EGD89902.2 - 1.6e-06 28.1 0.4 1.8e-06 27.9 0.4 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 EGD89902.2 - 0.015 15.4 2.6 0.024 14.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) COX14 PF14880.6 EGD89902.2 - 0.022 14.6 2.0 0.04 13.8 0.1 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Phage_holin_3_6 PF07332.11 EGD89902.2 - 0.03 14.4 1.9 0.038 14.0 1.9 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III LapA_dom PF06305.11 EGD89902.2 - 0.049 13.5 0.1 0.049 13.5 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4199 PF13858.6 EGD89902.2 - 6.7 7.1 8.6 2.6 8.4 2.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF4199) HD PF01966.22 EGD89904.1 - 0.00059 20.0 0.1 0.0042 17.3 0.0 2.3 2 1 0 2 2 2 1 HD domain HflK_N PF12221.8 EGD89904.1 - 0.0026 17.7 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial membrane protein N terminal PDEase_I PF00233.19 EGD89904.1 - 0.028 14.1 0.1 0.06 13.1 0.0 1.5 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase RMI1_C PF16099.5 EGD89904.1 - 0.089 12.6 0.0 0.29 11.0 0.0 1.8 3 0 0 3 3 3 0 Recq-mediated genome instability protein 1, C-terminal OB-fold SPX PF03105.19 EGD89906.1 - 4.8 7.0 5.8 5.5 6.8 5.8 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 EGD89906.1 - 6.2 5.9 9.5 6.3 5.9 9.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Arrestin_N PF00339.29 EGD89907.2 - 4.4e-12 46.3 0.1 1.2e-07 31.9 0.0 3.4 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EGD89907.2 - 0.028 13.8 0.4 0.096 12.1 0.0 2.0 3 0 0 3 3 3 0 Bul1 C terminus Mem_trans PF03547.18 EGD89908.1 - 0.28 9.5 2.0 0.37 9.1 2.0 1.3 1 0 0 1 1 1 0 Membrane transport protein Pyr_redox_2 PF07992.14 EGD89909.1 - 2.2e-52 178.1 0.3 2.8e-52 177.8 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EGD89909.1 - 1.8e-16 59.9 0.0 3.6e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EGD89909.1 - 6.5e-16 58.7 0.6 1.8e-13 50.9 0.4 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGD89909.1 - 2.6e-07 30.2 0.1 0.00013 21.3 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EGD89909.1 - 3.9e-06 27.3 0.0 1.1e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.6 EGD89909.1 - 3.4e-05 23.2 0.0 0.25 10.4 0.0 2.4 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGD89909.1 - 0.00019 21.4 0.2 0.63 10.0 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding DUF1188 PF06690.11 EGD89909.1 - 0.003 17.1 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) FIST PF08495.10 EGD89909.1 - 0.008 16.2 0.1 0.066 13.2 0.0 2.2 2 0 0 2 2 2 1 FIST N domain NAD_binding_7 PF13241.6 EGD89909.1 - 0.01 16.2 0.2 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 EGD89909.1 - 0.056 12.2 0.4 10 4.7 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein TrkA_N PF02254.18 EGD89909.1 - 0.15 12.4 0.2 11 6.3 0.1 2.7 2 0 0 2 2 2 0 TrkA-N domain SAM_2 PF07647.17 EGD89910.1 - 1.7e-07 31.3 0.1 3.6e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGD89910.1 - 0.0023 18.3 0.1 0.0066 16.9 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ADIP PF11559.8 EGD89911.1 - 6e-39 133.6 11.8 6e-39 133.6 11.8 2.5 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 EGD89911.1 - 0.0073 15.8 10.9 0.0073 15.8 10.9 2.4 2 0 0 2 2 2 1 Golgin subfamily A member 5 DUF3450 PF11932.8 EGD89911.1 - 0.048 13.0 9.5 0.18 11.1 9.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 EGD89911.1 - 0.16 11.7 9.6 0.12 12.2 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TTRAP PF14203.6 EGD89911.1 - 0.22 11.5 2.3 0.39 10.7 0.2 2.4 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein AAA_13 PF13166.6 EGD89911.1 - 0.23 10.0 4.8 0.45 9.1 4.8 1.4 1 0 0 1 1 1 0 AAA domain RasGAP_C PF03836.15 EGD89911.1 - 0.33 11.1 9.0 5.4 7.2 2.2 2.8 1 1 1 2 2 2 0 RasGAP C-terminus DUF641 PF04859.12 EGD89911.1 - 0.8 10.0 12.5 63 3.9 8.3 3.6 2 2 0 2 2 2 0 Plant protein of unknown function (DUF641) KxDL PF10241.9 EGD89911.1 - 1.4 9.3 10.9 0.18 12.1 5.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein HAUS6_N PF14661.6 EGD89911.1 - 1.4 8.4 5.6 4.1 6.9 5.6 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TRAF_BIRC3_bd PF16673.5 EGD89911.1 - 2.3 8.1 7.0 0.43 10.4 2.4 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Fib_alpha PF08702.10 EGD89911.1 - 3.6 7.8 12.8 0.95 9.6 7.6 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 EGD89911.1 - 5.3 6.2 5.6 13 4.9 5.6 1.7 1 0 0 1 1 1 0 TMPIT-like protein PKcGMP_CC PF16808.5 EGD89911.1 - 7.4 6.5 7.3 70 3.4 0.6 3.7 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Troponin PF00992.20 EGD89911.1 - 8.4 6.7 14.7 2.1 8.7 9.8 2.3 2 0 0 2 2 2 0 Troponin AKNA PF12443.8 EGD89911.1 - 9.8 6.9 10.8 3 8.5 3.1 3.8 4 1 1 5 5 5 0 AT-hook-containing transcription factor KASH_CCD PF14662.6 EGD89911.1 - 9.9 5.9 18.8 0.19 11.5 9.2 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH dUTPase PF00692.19 EGD89912.1 - 7.4e-44 148.5 0.0 9.5e-44 148.2 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 EGD89912.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Phos_pyr_kin PF08543.12 EGD89913.1 - 1.9e-11 43.8 0.0 3.1e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EGD89913.1 - 3.7e-08 33.0 0.0 1.3e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase BON PF04972.17 EGD89913.1 - 0.098 13.0 0.7 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 BON domain PQ-loop PF04193.14 EGD89914.1 - 6e-33 112.4 18.9 1e-17 63.6 1.3 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF3429 PF11911.8 EGD89914.1 - 0.014 15.7 3.0 0.024 14.9 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) ERGIC_N PF13850.6 EGD89914.1 - 0.12 12.7 0.5 0.9 9.9 0.0 2.5 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SPATA9 PF15824.5 EGD89914.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 APH PF01636.23 EGD89917.2 - 5.8e-23 82.1 0.1 9.5e-23 81.4 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGD89917.2 - 0.00075 18.9 0.1 0.0015 17.9 0.0 1.4 2 0 0 2 2 2 1 Ecdysteroid kinase NYD-SP28_assoc PF14775.6 EGD89917.2 - 0.19 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain Choline_kinase PF01633.20 EGD89917.2 - 0.26 10.9 0.0 0.38 10.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 EGD89917.2 - 0.31 9.9 0.0 0.4 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF4079 PF13301.6 EGD89918.2 - 0.021 14.9 12.6 0.076 13.2 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF998 PF06197.13 EGD89918.2 - 0.036 13.7 11.4 0.054 13.1 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF2427 PF10348.9 EGD89918.2 - 0.037 13.8 6.4 0.073 12.9 6.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) ATP-synt_DE_N PF02823.16 EGD89919.2 - 3.2e-15 55.8 0.0 5.1e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Ribosomal_L29e PF01779.17 EGD89920.1 - 5.2e-22 77.9 10.5 7.9e-22 77.3 10.5 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family NCBP3 PF10309.9 EGD89921.1 - 4.9e-24 83.9 0.1 1e-23 83.0 0.1 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Plug PF07715.15 EGD89921.1 - 0.022 15.3 1.1 1.1 9.8 0.1 3.2 2 1 1 3 3 3 0 TonB-dependent Receptor Plug Domain Cu-oxidase_3 PF07732.15 EGD89922.2 - 8.6e-12 45.1 0.4 4.4e-08 33.2 0.2 2.7 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGD89922.2 - 4e-10 39.5 0.1 0.0044 16.7 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Myb_DNA-binding PF00249.31 EGD89926.1 - 2.8e-26 91.4 2.2 9e-15 54.6 0.1 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGD89926.1 - 2.6e-18 66.0 5.8 5.5e-14 52.2 0.1 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain HTH_23 PF13384.6 EGD89926.1 - 0.14 12.0 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DUF2774 PF11242.8 EGD89926.1 - 0.14 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) RAB3GAP2_N PF14655.6 EGD89926.1 - 0.31 10.2 2.0 0.23 10.6 0.3 1.6 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Myb_DNA-bind_4 PF13837.6 EGD89926.1 - 0.46 10.9 0.0 0.46 10.9 0.0 2.7 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 EGD89928.2 - 1.1e-12 47.9 3.8 2.6e-09 37.1 0.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGD89928.2 - 1.6e-08 34.6 6.7 0.00032 20.9 0.2 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Methyltransf_28 PF02636.17 EGD89928.2 - 0.048 13.3 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase HTH_23 PF13384.6 EGD89928.2 - 0.049 13.4 0.1 0.091 12.6 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DUF2774 PF11242.8 EGD89928.2 - 0.054 13.7 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Ribosomal_L11_N PF03946.14 EGD89936.2 - 2.5e-23 81.7 0.3 3.9e-23 81.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGD89936.2 - 6.9e-15 55.3 0.0 1.2e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.15 EGD89937.2 - 6.6e-78 261.6 0.0 9.5e-78 261.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGD89937.2 - 8.5e-29 100.1 0.0 1.7e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EGD89937.2 - 5.5e-25 87.2 0.2 1.4e-24 85.8 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EGD89937.2 - 1.4e-14 53.8 4.5 2.6e-14 53.0 4.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGD89937.2 - 4.5e-11 42.5 0.0 1.2e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EGD89937.2 - 0.15 11.4 1.4 0.22 10.9 0.3 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain ADK PF00406.22 EGD89939.1 - 1.7e-36 125.6 0.0 7.5e-19 68.3 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 EGD89939.1 - 2.5e-16 59.4 0.0 4e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 EGD89939.1 - 4.6e-14 53.0 0.0 9.6e-13 48.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGD89939.1 - 5.1e-06 27.1 0.0 1.8e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGD89939.1 - 0.0031 17.7 0.0 0.015 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 EGD89939.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EGD89939.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EGD89939.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGD89939.1 - 0.18 11.8 0.1 0.32 11.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EGD89939.1 - 0.22 11.8 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SNase PF00565.17 EGD89940.1 - 5.7e-24 84.7 0.0 8.5e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Mito_carr PF00153.27 EGD89941.1 - 1.5e-57 191.5 2.0 2.7e-22 78.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3147 PF11345.8 EGD89941.1 - 0.047 14.1 1.7 0.076 13.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3147) CbiM PF01891.16 EGD89941.1 - 0.12 12.2 2.6 1.2 8.9 0.6 2.5 2 1 0 3 3 3 0 Cobalt uptake substrate-specific transmembrane region Peptidase_C2 PF00648.21 EGD89942.2 - 1.1e-24 87.1 0.0 1.6e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EGD89942.2 - 2.7e-08 34.2 0.0 1.7e-05 25.1 0.0 3.2 2 1 0 2 2 2 1 Calpain large subunit, domain III Vta1 PF04652.16 EGD89943.1 - 3.1e-54 182.9 6.8 3.1e-54 182.9 6.8 1.5 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EGD89943.1 - 2.2e-18 65.7 0.2 5.8e-18 64.3 0.2 1.8 1 0 0 1 1 1 1 Vta1 C-terminal domain Epimerase PF01370.21 EGD89945.1 - 3e-19 69.5 0.0 4.1e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGD89945.1 - 1.7e-10 40.4 0.0 3.3e-10 39.4 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGD89945.1 - 2e-07 30.4 0.0 3.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGD89945.1 - 3.8e-06 26.9 0.0 6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGD89945.1 - 0.00019 21.0 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EGD89945.1 - 0.0055 17.0 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EGD89945.1 - 0.087 12.7 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 KR domain Ldh_1_N PF00056.23 EGD89945.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Topoisom_I PF01028.20 EGD89946.2 - 8.3e-99 329.5 2.6 8.3e-99 329.5 2.6 2.1 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EGD89946.2 - 1.1e-71 240.7 2.3 1.1e-71 240.7 2.3 2.7 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EGD89946.2 - 2.4e-06 27.4 0.0 1.3e-05 25.0 0.0 2.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF89 PF01937.19 EGD89946.2 - 0.044 12.7 3.8 0.086 11.8 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF89 ATP-synt PF00231.19 EGD89947.2 - 5.6e-77 259.2 3.1 6.8e-77 258.9 3.1 1.0 1 0 0 1 1 1 1 ATP synthase Thioredoxin PF00085.20 EGD89950.1 - 6.7e-29 99.9 0.0 2.1e-24 85.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EGD89950.1 - 9e-06 26.1 0.0 0.0028 18.1 0.1 2.7 1 1 1 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EGD89950.1 - 1.5e-05 24.5 0.0 0.00024 20.6 0.0 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EGD89950.1 - 0.0035 17.3 0.0 0.051 13.5 0.0 2.6 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EGD89950.1 - 0.0099 16.2 0.1 0.56 10.6 0.0 3.2 3 1 0 3 3 3 1 Thioredoxin-like TraF PF13728.6 EGD89950.1 - 0.046 13.5 0.0 0.046 13.5 0.0 4.2 4 0 0 4 4 4 0 F plasmid transfer operon protein GNAT_acetyltr_2 PF13718.6 EGD89951.1 - 2.7e-98 327.9 0.0 4.8e-98 327.1 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EGD89951.1 - 4.1e-91 304.9 0.0 7.6e-91 304.0 0.0 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EGD89951.1 - 4.9e-65 218.7 0.0 1.3e-64 217.3 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EGD89951.1 - 1e-34 118.4 0.0 2.8e-34 116.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EGD89951.1 - 0.00036 20.3 0.1 0.051 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 EGD89951.1 - 0.016 15.5 0.0 0.064 13.5 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AAA_22 PF13401.6 EGD89951.1 - 0.025 14.9 0.0 0.46 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Glyco_transf_90 PF05686.12 EGD89952.2 - 2.6e-12 46.4 0.1 4.3e-06 25.9 0.0 3.4 3 1 0 3 3 3 2 Glycosyl transferase family 90 Glyco_hydro_16 PF00722.21 EGD89953.1 - 5.3e-08 32.5 0.0 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Vps8 PF12816.7 EGD89955.1 - 5.6e-65 218.6 0.1 5.6e-65 218.6 0.1 2.5 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EGD89955.1 - 1.5e-07 31.3 6.9 0.0053 16.6 0.1 4.1 5 1 0 5 5 5 2 Region in Clathrin and VPS Pox_D3 PF04580.13 EGD89955.1 - 0.013 15.2 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-C3H2C3 PF17122.5 EGD89955.1 - 0.13 12.3 0.1 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger WD40 PF00400.32 EGD89955.1 - 0.15 13.0 1.2 0.4 11.6 0.1 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-RING_2 PF13639.6 EGD89955.1 - 0.75 10.2 2.0 1.3 9.4 0.1 2.4 3 0 0 3 3 3 0 Ring finger domain zf-HC5HC2H_2 PF13832.6 EGD89956.2 - 1.7e-23 82.9 0.9 1.7e-23 82.9 0.9 4.3 5 0 0 5 5 5 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGD89956.2 - 6.1e-21 74.5 3.0 6.1e-21 74.5 3.0 4.6 4 0 0 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.18 EGD89956.2 - 1.1e-15 57.5 0.0 2.4e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 EGD89956.2 - 3.2e-13 49.3 46.3 4.6e-07 29.6 7.3 5.2 5 0 0 5 5 5 3 PHD-finger PHD_2 PF13831.6 EGD89956.2 - 9.5e-09 34.7 2.9 9.5e-09 34.7 2.9 4.1 5 0 0 5 5 5 1 PHD-finger C1_1 PF00130.22 EGD89956.2 - 0.0093 15.8 2.2 0.0093 15.8 2.2 6.0 6 1 1 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EGD89956.2 - 0.058 13.7 0.2 0.058 13.7 0.2 6.1 6 0 0 6 6 6 0 C1 domain Myb_DNA-binding PF00249.31 EGD89956.2 - 0.062 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain JAB PF01398.21 EGD89958.2 - 1.4e-12 47.7 0.0 2.8e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EGD89958.2 - 4.5e-07 29.6 0.4 1.2e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.11 EGD89958.2 - 4.4e-06 26.9 0.1 9.5e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain Syntaxin-6_N PF09177.11 EGD89958.2 - 0.0013 19.2 1.2 0.0025 18.4 0.7 1.7 1 1 0 1 1 1 1 Syntaxin 6, N-terminal DivIVA PF05103.13 EGD89960.1 - 0.00077 19.6 21.3 0.0092 16.1 7.1 3.5 2 1 1 3 3 3 2 DivIVA protein DUF4407 PF14362.6 EGD89960.1 - 0.0063 15.9 6.0 0.0063 15.9 6.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) HAP1_N PF04849.13 EGD89960.1 - 0.032 13.5 0.2 0.032 13.5 0.2 2.8 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Fib_alpha PF08702.10 EGD89960.1 - 1.8 8.7 16.5 2 8.6 6.5 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family PET117 PF15786.5 EGD89961.1 - 2.5e-26 91.7 1.2 2.9e-26 91.5 1.2 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial THEG4 PF15834.5 EGD89961.1 - 0.16 12.0 0.1 0.22 11.5 0.1 1.3 1 1 0 1 1 1 0 Testis highly expressed protein 4 V-ATPase_G PF03179.15 EGD89962.2 - 1.9e-26 92.6 17.8 2.4e-26 92.3 17.8 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EGD89962.2 - 0.014 15.4 18.1 0.019 15.1 10.1 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 EGD89962.2 - 0.016 15.6 14.4 0.045 14.2 14.4 1.7 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit OmpH PF03938.14 EGD89962.2 - 0.33 11.3 15.2 0.41 11.0 15.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ATP11 PF06644.11 EGD89962.2 - 1.3 8.8 11.0 1.4 8.7 11.0 1.0 1 0 0 1 1 1 0 ATP11 protein DUF3552 PF12072.8 EGD89962.2 - 2.5 7.5 20.3 6.7 6.1 20.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) CENP-I PF07778.11 EGD89962.2 - 9.2 4.8 6.9 10 4.7 6.9 1.0 1 0 0 1 1 1 0 Mis6 Helicase_C PF00271.31 EGD89964.2 - 1.1e-20 74.0 0.2 2.9e-20 72.7 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD89964.2 - 2.3e-10 40.7 0.0 3.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGD89964.2 - 1.4e-08 34.7 0.0 5.5e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EGD89964.2 - 0.0031 16.8 0.0 0.0057 15.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 EGD89964.2 - 0.071 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase F_actin_cap_B PF01115.17 EGD89965.1 - 1.1e-105 352.6 0.0 1.3e-105 352.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Med11 PF10280.9 EGD89966.1 - 5.9e-42 143.4 0.5 7.3e-42 143.1 0.5 1.1 1 0 0 1 1 1 1 Mediator complex protein DUF2298 PF10060.9 EGD89966.1 - 0.14 10.9 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) WD40 PF00400.32 EGD89967.2 - 4.8e-48 160.1 30.0 6.2e-09 36.4 0.4 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD89967.2 - 9.8e-15 54.6 1.4 0.018 15.3 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD89967.2 - 5.1e-07 28.7 2.7 0.0001 21.1 0.1 3.7 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGD89967.2 - 0.00032 19.8 0.3 0.053 12.5 0.0 3.2 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGD89967.2 - 0.0015 17.4 0.1 0.94 8.1 0.0 3.2 2 1 1 3 3 3 2 Nup133 N terminal like eIF2A PF08662.11 EGD89967.2 - 0.0088 15.9 0.2 0.043 13.7 0.1 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF4550 PF15084.6 EGD89967.2 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) RAB3GAP2_N PF14655.6 EGD89967.2 - 0.17 11.1 0.1 7.8 5.6 0.0 2.8 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PALB2_WD40 PF16756.5 EGD89967.2 - 3.6 6.4 5.5 0.61 8.9 0.8 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Abhydrolase_6 PF12697.7 EGD89968.1 - 3.1e-23 83.5 0.1 4.4e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGD89968.1 - 3.3e-10 40.1 0.0 4.6e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD89968.1 - 2.2e-05 23.9 0.0 3.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGD89968.1 - 0.049 13.7 0.1 0.46 10.6 0.1 2.1 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 EGD89968.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EGD89968.1 - 0.1 12.5 0.1 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase DUF676 PF05057.14 EGD89968.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2417 PF10329.9 EGD89969.1 - 8.9e-81 270.8 0.3 1.2e-80 270.3 0.3 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Trp_oprn_chp PF09534.10 EGD89969.1 - 0.085 12.6 4.1 0.039 13.8 1.0 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SP_C-Propep PF08999.10 EGD89969.1 - 0.31 10.8 1.8 1.9 8.3 1.3 2.2 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide PMSR PF01625.21 EGD89970.1 - 2.9e-60 202.9 0.8 3.4e-60 202.7 0.8 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Pro_dh PF01619.18 EGD89971.1 - 2.7e-62 211.0 0.0 4e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Ribosomal_60s PF00428.19 EGD89972.1 - 0.047 14.3 7.6 0.073 13.7 7.6 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein GFA PF04828.14 EGD89972.1 - 0.065 13.6 1.5 0.17 12.2 1.5 1.7 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_16 PF00722.21 EGD89973.2 - 1.2e-22 80.2 3.4 3.4e-17 62.5 0.7 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 16 Lipocalin_4 PF13648.6 EGD89973.2 - 0.21 12.6 7.9 0.26 12.3 2.7 2.3 2 0 0 2 2 2 0 Lipocalin-like domain Alk_phosphatase PF00245.20 EGD89974.1 - 4.3e-107 358.6 0.0 5.7e-107 358.2 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EGD89974.1 - 3.2e-05 23.4 0.1 7.5e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily DUF498 PF04430.14 EGD89975.1 - 1.5e-31 108.7 0.0 2.1e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) ABC_membrane PF00664.23 EGD89976.2 - 1.6e-35 123.1 8.1 1.6e-35 123.1 8.1 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGD89976.2 - 1.8e-33 116.0 0.0 4.3e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGD89976.2 - 5.4e-08 32.5 0.1 7.1e-06 25.6 0.0 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGD89976.2 - 0.013 15.8 0.0 0.066 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EGD89976.2 - 0.014 15.6 0.5 0.4 11.0 0.5 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGD89976.2 - 0.042 13.6 0.2 0.1 12.4 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGD89976.2 - 0.046 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EGD89976.2 - 0.081 13.3 1.3 0.48 10.8 1.3 2.2 1 1 0 1 1 1 0 AAA ATPase domain WD40 PF00400.32 EGD89978.1 - 2.1e-14 53.6 12.5 5.9e-06 26.9 0.4 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD89978.1 - 2.3e-06 27.8 0.0 1.1 9.6 0.0 4.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGD89978.1 - 0.0039 17.1 0.0 0.056 13.3 0.0 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Zn_ribbon_17 PF17120.5 EGD89978.1 - 0.014 15.1 7.5 0.04 13.5 7.5 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PD40 PF07676.12 EGD89978.1 - 0.061 13.3 1.0 0.33 10.9 0.1 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat zinc_ribbon_16 PF17034.5 EGD89978.1 - 0.51 10.6 7.1 2.1 8.6 0.6 2.6 2 0 0 2 2 2 0 Zinc-ribbon like family Forkhead PF00250.18 EGD89979.2 - 8.4e-17 61.2 0.2 1.6e-16 60.3 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain XLF PF09302.11 EGD89981.2 - 9e-56 188.9 0.1 1.4e-55 188.2 0.1 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component NYD-SP28 PF14772.6 EGD89981.2 - 0.1 12.6 0.1 0.35 10.9 0.1 1.8 1 0 0 1 1 1 0 Sperm tail Ribosomal_L34e PF01199.18 EGD89982.1 - 4.4e-43 145.5 2.9 6.6e-43 144.9 2.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 EGD89982.1 - 0.031 13.7 1.4 0.041 13.3 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 EGD89982.1 - 0.66 10.0 5.1 3.5 7.7 0.3 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain PROCN PF08083.11 EGD89983.1 - 7.1e-236 782.5 9.0 7.1e-236 782.5 9.0 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EGD89983.1 - 1.3e-126 420.9 2.6 2.2e-126 420.1 2.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EGD89983.1 - 5.5e-84 279.9 2.0 1.9e-57 193.6 0.3 3.1 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EGD89983.1 - 9e-81 269.2 1.8 2.6e-80 267.7 1.8 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EGD89983.1 - 1.5e-70 235.4 0.1 3.3e-70 234.4 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 EGD89983.1 - 3.3e-48 162.7 0.1 1e-47 161.1 0.1 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 EGD89983.1 - 3.6e-48 161.8 0.3 9.5e-48 160.5 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end_hint PF05203.16 EGD89983.1 - 1e-07 32.2 0.0 1e-07 32.2 0.0 2.0 2 0 0 2 2 2 1 Hom_end-associated Hint Hom_end PF05204.14 EGD89983.1 - 0.008 16.3 0.0 0.027 14.6 0.0 1.9 1 0 0 1 1 1 1 Homing endonuclease APH PF01636.23 EGD89984.1 - 0.084 12.8 0.0 0.24 11.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family CTP_synth_N PF06418.14 EGD89985.2 - 2e-66 224.0 0.0 2.6e-66 223.6 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EGD89985.2 - 7.1e-56 189.0 0.0 1.1e-55 188.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGD89985.2 - 6.2e-06 26.1 0.5 6.9e-05 22.7 0.5 2.3 1 1 0 1 1 1 1 Peptidase C26 Ribosomal_L32p PF01783.23 EGD89986.1 - 0.16 12.2 0.3 0.52 10.6 0.0 1.9 2 0 0 2 2 2 0 Ribosomal L32p protein family Myb_DNA-bind_6 PF13921.6 EGD89988.1 - 8.8e-13 48.3 0.0 7.1e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGD89988.1 - 1.8e-10 40.8 0.1 0.00021 21.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain COX5B PF01215.19 EGD89990.1 - 4.2e-55 184.9 0.0 5.7e-55 184.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 EGD89990.1 - 0.034 13.9 0.1 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Myb_DNA-binding PF00249.31 EGD89992.2 - 9.9e-16 57.7 3.0 2.8e-09 37.0 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGD89992.2 - 5.4e-10 39.4 1.0 2.4e-06 27.7 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGD89992.2 - 0.03 14.2 0.7 0.065 13.1 0.4 1.6 1 1 0 1 1 1 0 Myb DNA-binding like Ndc1_Nup PF09531.10 EGD89992.2 - 3.5 6.2 7.3 3.7 6.1 7.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 EGD89992.2 - 4.3 6.4 7.5 4.8 6.3 7.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PXPV PF12778.7 EGD89996.2 - 0.043 13.7 0.5 0.043 13.7 0.5 1.5 2 0 0 2 2 2 0 PXPV repeat (3 copies) eRF1_1 PF03463.15 EGD89997.1 - 2.1e-45 153.9 0.0 9.7e-45 151.7 0.0 2.0 1 1 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 EGD89997.1 - 1.6e-17 64.0 0.0 2.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 EGD89997.1 - 5.7e-16 59.0 0.0 1.5e-15 57.7 0.0 1.7 1 1 0 1 1 1 1 eRF1 domain 2 LptE PF04390.12 EGD89997.1 - 0.1 13.3 0.0 0.27 11.9 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Aldo_ket_red PF00248.21 EGD90000.1 - 5.9e-45 153.7 0.0 1.3e-42 146.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SCHIP-1 PF10148.9 EGD90000.1 - 0.00037 20.2 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 Dev_Cell_Death PF10539.9 EGD90000.1 - 0.015 15.2 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 Development and cell death domain Ribosomal_S19e PF01090.19 EGD90002.1 - 1.5e-58 196.3 0.2 1.7e-58 196.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_1 PF00561.20 EGD90003.1 - 4.1e-14 52.9 0.0 8.2e-13 48.6 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD90003.1 - 7.1e-13 49.7 1.0 1.7e-12 48.4 0.4 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGD90003.1 - 2.1e-12 46.8 0.0 9.5e-12 44.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 EGD90003.1 - 2.1e-07 30.8 0.0 5e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Chlorophyllase2 PF12740.7 EGD90003.1 - 8.9e-05 21.5 0.0 0.0011 18.0 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase enzyme PGAP1 PF07819.13 EGD90003.1 - 0.00014 21.7 0.1 0.00057 19.7 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Ser_hydrolase PF06821.13 EGD90003.1 - 0.00036 20.4 0.1 0.00071 19.5 0.1 1.4 1 0 0 1 1 1 1 Serine hydrolase Y_phosphatase PF00102.27 EGD90003.1 - 0.0011 18.6 0.0 0.0038 16.8 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase LIDHydrolase PF10230.9 EGD90003.1 - 0.0011 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PTPlike_phytase PF14566.6 EGD90003.1 - 0.0018 18.4 0.0 0.003 17.7 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Thioesterase PF00975.20 EGD90003.1 - 0.02 15.0 0.3 0.042 14.0 0.1 1.6 2 0 0 2 2 2 0 Thioesterase domain LCAT PF02450.15 EGD90003.1 - 0.035 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PAF-AH_p_II PF03403.13 EGD90003.1 - 0.11 11.0 0.4 0.4 9.1 0.1 1.8 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF900 PF05990.12 EGD90003.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) ILVD_EDD PF00920.21 EGD90004.2 - 4e-186 619.6 1.7 5e-186 619.3 1.7 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1772 PF08592.11 EGD90005.1 - 1e-30 106.8 1.2 1.4e-30 106.4 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Pex2_Pex12 PF04757.14 EGD90006.1 - 4e-36 124.7 0.7 5.6e-36 124.2 0.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 EGD90006.1 - 0.016 15.1 1.8 0.041 13.8 1.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGD90006.1 - 0.021 14.9 5.5 0.021 14.9 5.5 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGD90006.1 - 0.042 13.9 6.1 0.23 11.5 6.1 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGD90006.1 - 0.16 11.8 5.3 0.3 11.0 1.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBN_N PF03810.19 EGD90007.1 - 1.7e-14 53.5 0.0 8.9e-14 51.2 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGD90007.1 - 0.00042 20.4 0.8 0.011 15.8 0.0 3.4 4 0 0 4 4 4 1 Exportin 1-like protein DUF3385 PF11865.8 EGD90007.1 - 0.023 14.6 0.3 0.092 12.7 0.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) Cellulase PF00150.18 EGD90008.1 - 2e-15 57.0 0.1 7e-15 55.2 0.1 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GST_N_3 PF13417.6 EGD90009.2 - 2.2e-16 60.0 0.0 4e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGD90009.2 - 1.1e-13 51.3 0.0 1.9e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGD90009.2 - 3.1e-07 30.3 0.0 6.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGD90009.2 - 2.3e-05 24.6 0.1 9.8e-05 22.6 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGD90009.2 - 0.023 14.9 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GPI-anchored PF10342.9 EGD90012.1 - 1.2e-23 83.6 0.3 2.5e-23 82.6 0.0 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_transf_90 PF05686.12 EGD90013.1 - 2.1e-35 122.4 3.0 5.9e-35 120.9 3.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 90 DUF16 PF01519.16 EGD90015.1 - 0.0024 18.3 3.5 0.0056 17.2 3.5 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF16 GOLGA2L5 PF15070.6 EGD90015.1 - 0.055 12.1 13.2 0.081 11.6 13.2 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Prefoldin_2 PF01920.20 EGD90015.1 - 4.7 7.2 9.4 11 6.1 2.9 2.4 1 1 1 2 2 2 0 Prefoldin subunit Gly_transf_sug PF04488.15 EGD90016.1 - 2.1e-10 41.1 0.0 6.3e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EGD90016.1 - 0.014 14.8 0.0 0.014 14.8 0.0 2.0 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein RR_TM4-6 PF06459.12 EGD90016.1 - 0.22 11.3 13.2 0.37 10.6 13.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 EGD90016.1 - 0.34 9.6 7.7 0.49 9.1 7.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.11 EGD90016.1 - 0.57 8.6 16.3 0.69 8.3 16.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein NPR3 PF03666.13 EGD90016.1 - 1.4 7.7 13.9 1.9 7.2 13.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 EGD90016.1 - 4.2 7.5 6.7 6.5 6.8 6.7 1.4 1 0 0 1 1 1 0 DDHD domain DUF2462 PF09495.10 EGD90017.1 - 1.4e-23 83.4 11.2 1.4e-23 83.4 11.2 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) DUF5427 PF10310.9 EGD90018.1 - 4e-167 556.9 0.0 4.9e-167 556.6 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 EGD90018.1 - 0.004 17.3 0.1 0.012 15.8 0.1 1.8 1 0 0 1 1 1 1 Influenza Matrix protein (M1) C-terminal domain ORC6 PF05460.13 EGD90018.1 - 0.43 9.8 4.2 0.66 9.2 4.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TSP9 PF11493.8 EGD90018.1 - 2.3 8.9 4.5 1 10.1 0.1 2.8 3 0 0 3 3 3 0 Thylakoid soluble phosphoprotein TSP9 HA2 PF04408.23 EGD90020.2 - 5.7e-21 74.8 2.1 8e-21 74.4 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGD90020.2 - 1.9e-17 63.4 0.0 9.3e-17 61.2 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGD90020.2 - 2.7e-15 56.7 0.1 8.6e-15 55.0 0.0 1.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGD90020.2 - 0.065 13.0 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase DAD PF02109.16 EGD90021.1 - 1.1e-32 112.6 0.1 1.4e-32 112.3 0.1 1.1 1 0 0 1 1 1 1 DAD family RTC4 PF14474.6 EGD90023.2 - 9.3e-30 103.3 0.0 1.9e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain DUF726 PF05277.12 EGD90024.1 - 2.2e-127 424.7 2.8 2.2e-127 424.7 2.8 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Metallophos PF00149.28 EGD90026.1 - 3.5e-11 44.0 1.6 6.6e-11 43.1 1.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGD90026.1 - 7.5e-06 26.2 0.4 6.8e-05 23.1 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EGD90026.1 - 0.12 11.7 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Mito_carr PF00153.27 EGD90027.1 - 2.1e-73 242.3 0.3 4.3e-25 87.5 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EGD90027.1 - 1.8e-13 50.7 6.7 5.2e-09 36.4 0.8 3.5 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 EGD90027.1 - 1.5e-11 43.3 6.8 6.9e-07 28.7 0.1 5.5 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 EGD90027.1 - 1.5e-10 39.9 11.0 8.4e-07 28.1 0.1 5.6 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 EGD90027.1 - 1.3e-06 28.2 0.7 2.1 8.2 0.0 5.0 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 EGD90027.1 - 2.6e-06 26.6 2.5 5.7e-05 22.4 0.1 3.4 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 EGD90027.1 - 0.086 13.2 0.0 23 5.4 0.0 3.5 3 0 0 3 3 3 0 EF-hand domain Pyr_redox_2 PF07992.14 EGD90029.2 - 0.0003 20.1 0.0 0.0068 15.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGD90029.2 - 0.027 14.7 0.0 0.27 11.5 0.0 2.4 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 EGD90029.2 - 0.034 14.2 0.0 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 EGD90029.2 - 0.11 11.6 0.0 0.3 10.2 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EGD90029.2 - 0.18 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BSMAP PF12280.8 EGD90029.2 - 0.18 12.0 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein NAD_binding_2 PF03446.15 EGD90029.2 - 0.18 11.9 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_transf_25 PF01755.17 EGD90030.1 - 8.3e-06 25.8 0.0 2.8e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) CEP44 PF15007.6 EGD90032.1 - 0.16 12.2 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 Peptidase_M22 PF00814.25 EGD90033.1 - 2.3e-44 152.2 0.0 6.2e-40 137.6 0.0 3.3 2 1 0 2 2 2 2 Glycoprotease family Myb_DNA-bind_6 PF13921.6 EGD90034.1 - 6.8e-09 35.8 1.3 6.6e-08 32.7 0.4 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGD90034.1 - 2.7e-06 27.5 0.2 1.5e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain EPL1 PF10513.9 EGD90037.2 - 2.4e-32 112.5 0.0 4.4e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.6 EGD90037.2 - 6.4e-32 110.0 3.6 6.4e-32 110.0 3.6 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGD90037.2 - 6e-28 96.9 1.3 6e-28 96.9 1.3 2.8 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.6 EGD90037.2 - 3.5e-14 52.1 2.9 3.5e-14 52.1 2.9 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EGD90037.2 - 6.9e-09 35.5 9.8 6.9e-09 35.5 9.8 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 EGD90037.2 - 0.011 15.4 2.1 0.011 15.4 2.1 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Dpy-30 PF05186.13 EGD90039.1 - 4.7e-14 51.8 0.0 6.5e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif VRR_NUC PF08774.11 EGD90040.1 - 9.3e-24 83.6 0.0 2.5e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Ribosomal_S13_N PF08069.12 EGD90041.1 - 9.1e-30 102.5 0.2 1.5e-29 101.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EGD90041.1 - 2.3e-15 56.6 0.2 3.3e-15 56.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EGD90041.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain Chromate_transp PF02417.15 EGD90042.1 - 1.8e-57 193.9 34.2 4.8e-31 108.0 13.8 2.4 3 0 0 3 3 3 2 Chromate transporter NDUF_B12 PF08122.12 EGD90042.1 - 0.075 13.1 4.2 52 4.0 0.1 5.2 4 1 1 5 5 5 0 NADH-ubiquinone oxidoreductase B12 subunit family RRM_1 PF00076.22 EGD90047.2 - 1.8e-31 107.8 0.3 2.3e-13 49.7 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGD90047.2 - 1.5e-07 31.1 0.0 0.046 13.6 0.0 3.4 3 0 0 3 3 3 3 Occluded RNA-recognition motif Vpu PF00558.19 EGD90048.2 - 0.33 10.8 2.4 0.68 9.7 0.1 2.1 2 0 0 2 2 2 0 Vpu protein Pyr_redox_3 PF13738.6 EGD90049.2 - 4.8e-10 39.2 0.0 0.0047 16.2 0.0 3.4 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGD90049.2 - 1.4e-08 34.4 0.0 0.00077 18.8 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGD90049.2 - 2.5e-08 34.0 0.0 5.1e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGD90049.2 - 1.6e-07 31.3 0.0 0.013 15.2 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase FMO-like PF00743.19 EGD90049.2 - 2.4e-07 29.6 0.7 0.00073 18.1 0.0 3.3 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EGD90049.2 - 3.7e-05 23.0 0.0 0.56 9.3 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGD90049.2 - 4.2e-05 23.6 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 EGD90049.2 - 0.00032 20.0 0.2 0.026 13.8 0.0 2.9 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 EGD90049.2 - 0.0091 15.1 0.1 0.17 11.0 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGD90049.2 - 0.13 10.9 0.1 5.9 5.5 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein Fungal_trans_2 PF11951.8 EGD90052.2 - 8.9e-08 31.3 1.4 1.6e-07 30.5 1.4 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Rax2 PF12768.7 EGD90053.1 - 7.9e-69 231.4 0.0 6e-68 228.5 0.0 2.5 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Reg_prop PF07494.11 EGD90053.1 - 0.0057 16.7 0.9 41 4.9 0.0 5.2 5 0 0 5 5 5 2 Two component regulator propeller SSrecog PF03531.14 EGD90054.2 - 2.1e-30 104.4 0.2 3.6e-29 100.5 0.0 3.0 4 0 0 4 4 4 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 EGD90054.2 - 6.6e-30 103.4 0.5 1.2e-28 99.3 0.1 2.6 3 0 0 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 EGD90054.2 - 1.2e-25 89.7 0.1 5.4e-25 87.6 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SAP PF02037.27 EGD90055.1 - 4e-12 45.6 0.6 6.6e-12 44.9 0.1 1.7 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 EGD90055.1 - 1.2e-06 28.2 0.1 1.2e-06 28.2 0.1 2.9 3 0 0 3 3 3 1 Tho1/MOS11 C-terminal domain CCT_2 PF09425.10 EGD90055.1 - 0.1 12.5 6.5 0.85 9.6 1.3 2.7 2 0 0 2 2 2 0 Divergent CCT motif Endomucin PF07010.12 EGD90055.1 - 0.7 9.8 9.1 0.94 9.4 9.1 1.2 1 0 0 1 1 1 0 Endomucin Hamartin PF04388.12 EGD90055.1 - 0.95 8.1 6.9 1.1 7.9 6.9 1.1 1 0 0 1 1 1 0 Hamartin protein DUF966 PF06136.13 EGD90055.1 - 1.4 8.6 7.2 1.9 8.1 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FXMRP1_C_core PF12235.8 EGD90055.1 - 1.4 9.5 14.3 0.34 11.6 5.3 2.6 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Presenilin PF01080.17 EGD90055.1 - 9.1 4.9 6.0 13 4.5 6.0 1.3 1 0 0 1 1 1 0 Presenilin Methyltransf_11 PF08241.12 EGD90056.1 - 0.00053 20.6 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD90056.1 - 0.025 15.3 0.0 0.054 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EGD90056.1 - 0.037 13.2 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF3455 PF11937.8 EGD90057.2 - 4.3e-21 75.9 0.1 3.4e-19 69.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3455) SF3b1 PF08920.10 EGD90058.2 - 1.1e-32 113.0 13.0 1.6e-32 112.5 7.4 3.1 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 EGD90058.2 - 6e-11 42.6 8.6 0.21 12.0 0.1 7.9 6 2 3 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 EGD90058.2 - 8.6e-11 42.1 2.9 0.011 16.2 0.0 6.7 7 1 1 8 8 6 2 HEAT-like repeat HEAT PF02985.22 EGD90058.2 - 2.2e-08 33.6 9.3 0.71 10.3 0.2 8.7 9 0 0 9 9 8 1 HEAT repeat Cnd1 PF12717.7 EGD90058.2 - 1.6e-05 25.0 1.1 5 7.1 0.0 6.2 5 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGD90058.2 - 4.4e-05 24.0 0.2 2.4 8.8 0.0 5.4 6 0 0 6 6 5 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EGD90058.2 - 0.00019 21.4 0.9 0.061 13.2 0.0 4.7 6 1 0 6 6 6 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 EGD90058.2 - 0.00021 21.0 0.2 1.2 8.7 0.0 4.1 5 0 0 5 5 5 2 NUC173 domain UNC45-central PF11701.8 EGD90058.2 - 0.00097 19.1 0.0 0.0036 17.3 0.0 1.9 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central UME PF08064.13 EGD90058.2 - 0.0051 16.7 0.5 8.5 6.4 0.0 4.8 7 0 0 7 7 6 1 UME (NUC010) domain CLASP_N PF12348.8 EGD90058.2 - 0.0053 16.3 0.1 0.95 9.0 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal TAF6_C PF07571.13 EGD90058.2 - 0.022 15.1 0.0 1.1 9.6 0.0 3.4 3 1 0 3 3 2 0 TAF6 C-terminal HEAT repeat domain DRIM PF07539.12 EGD90058.2 - 0.089 11.1 0.2 8.6 4.5 0.0 3.6 2 1 2 4 4 4 0 Down-regulated in metastasis CRM1_C PF08767.11 EGD90058.2 - 0.17 11.0 0.2 0.63 9.1 0.0 2.0 2 0 0 2 2 2 0 CRM1 C terminal Ecm29 PF13001.7 EGD90058.2 - 0.18 10.4 0.0 1.6 7.3 0.0 2.3 2 1 1 3 3 3 0 Proteasome stabiliser DUF1192 PF06698.11 EGD90058.2 - 7 6.8 6.4 20 5.3 0.7 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) CDC45 PF02724.14 EGD90058.2 - 9.7 4.3 8.5 11 4.2 7.2 1.6 2 0 0 2 2 2 0 CDC45-like protein Sec1 PF00995.23 EGD90059.1 - 5.8e-120 402.2 0.0 6.5e-120 402.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Transposase_22 PF02994.14 EGD90059.1 - 0.0058 16.8 0.0 0.17 12.1 0.0 2.8 3 0 0 3 3 3 1 L1 transposable element RBD-like domain V-SNARE_C PF12352.8 EGD90060.1 - 1.4 9.2 7.3 0.092 13.0 0.8 2.3 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus zf-C2H2 PF00096.26 EGD90061.1 - 5.4e-10 39.2 11.4 1.5e-05 25.1 4.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 EGD90061.1 - 8.1e-06 26.1 3.6 2e-05 24.8 1.2 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EGD90061.1 - 2.2e-05 24.7 29.2 2.6e-05 24.4 0.4 3.9 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGD90061.1 - 7.9e-05 22.6 8.7 0.00015 21.7 2.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGD90061.1 - 0.00019 22.0 18.7 0.00065 20.3 2.9 2.9 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGD90061.1 - 0.00073 19.8 2.0 0.00073 19.8 2.0 3.4 4 0 0 4 4 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EGD90061.1 - 0.032 14.1 4.3 3.2 7.7 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PAT1 PF09770.9 EGD90061.1 - 0.042 12.1 17.7 0.055 11.7 17.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.13 EGD90061.1 - 0.16 11.7 3.8 0.24 11.1 3.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spt20 PF12090.8 EGD90061.1 - 0.17 11.5 26.8 0.28 10.8 26.8 1.3 1 0 0 1 1 1 0 Spt20 family Actin_micro PF17003.5 EGD90061.1 - 0.21 10.8 0.2 0.37 9.9 0.2 1.3 1 0 0 1 1 1 0 Putative actin-like family CTU2 PF10288.9 EGD90061.1 - 0.26 11.5 7.4 5.4 7.3 5.0 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Hydin_ADK PF17213.3 EGD90061.1 - 0.44 10.8 9.2 23 5.2 8.7 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 EGD90061.1 - 0.46 9.2 8.2 0.64 8.7 8.2 1.1 1 0 0 1 1 1 0 Presenilin DUF775 PF05603.12 EGD90061.1 - 0.46 10.0 8.0 0.71 9.4 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4175 PF13779.6 EGD90061.1 - 0.51 8.2 14.8 0.65 7.8 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) zf-BED PF02892.15 EGD90061.1 - 0.53 10.4 3.6 0.36 10.9 0.4 2.1 2 0 0 2 2 2 0 BED zinc finger Suf PF05843.14 EGD90061.1 - 0.75 9.7 13.5 0.32 11.0 10.6 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 EGD90061.1 - 0.76 9.8 7.6 0.46 10.5 4.0 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-C2H2_11 PF16622.5 EGD90061.1 - 0.93 9.3 7.3 8 6.3 0.8 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type Endostatin PF06482.11 EGD90061.1 - 1 8.8 10.1 1.7 8.0 10.1 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Zip PF02535.22 EGD90061.1 - 1.9 7.6 3.8 2.7 7.1 3.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Het-C PF07217.11 EGD90061.1 - 3.7 6.0 5.9 5 5.5 5.9 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C TFIIA PF03153.13 EGD90061.1 - 3.8 7.4 38.4 4.4 7.2 37.6 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EGD90061.1 - 5.3 5.6 7.8 5.9 5.5 7.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4834 PF16118.5 EGD90061.1 - 9.7 7.2 13.5 4.1 8.4 10.5 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) FAD_binding_2 PF00890.24 EGD90067.2 - 5.4e-31 108.1 1.3 7.7e-29 101.0 1.3 2.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGD90067.2 - 0.00015 21.3 0.1 0.00021 20.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGD90067.2 - 0.0021 17.3 1.1 0.025 13.8 1.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGD90067.2 - 0.013 14.2 5.1 0.27 9.9 0.8 3.1 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 EGD90067.2 - 0.061 12.4 5.0 0.13 11.3 2.3 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A DAO PF01266.24 EGD90067.2 - 3.5 7.1 7.4 2.1 7.9 2.4 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.18 EGD90068.2 - 6.9e-23 81.0 0.1 1e-22 80.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Vel1p PF10339.9 EGD90068.2 - 0.087 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Yeast-specific zinc responsive DDE_Tnp_1_3 PF13612.6 EGD90068.2 - 0.19 11.7 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain ThiF PF00899.21 EGD90070.2 - 2.9e-66 223.3 0.0 6.9e-66 222.1 0.0 1.4 1 1 1 2 2 2 1 ThiF family E2_bind PF08825.10 EGD90070.2 - 1.9e-29 101.6 0.4 3.1e-29 100.9 0.4 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EGD90070.2 - 0.00077 19.5 1.0 0.0013 18.8 0.0 1.8 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase E1_UFD PF09358.10 EGD90070.2 - 0.004 17.8 0.0 0.011 16.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain Sacchrp_dh_NADP PF03435.18 EGD90070.2 - 0.012 15.8 0.3 0.22 11.8 0.1 2.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 EGD90070.2 - 0.03 14.9 0.1 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.8 EGD90070.2 - 0.032 14.4 2.0 0.07 13.3 2.0 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein NAD_binding_7 PF13241.6 EGD90070.2 - 0.099 13.1 0.1 1.2 9.6 0.0 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EGD90070.2 - 0.1 12.2 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglD_N PF17836.1 EGD90070.2 - 0.15 12.7 1.7 0.37 11.5 0.8 2.1 1 1 1 2 2 2 0 PglD N-terminal domain UBA_e1_thiolCys PF10585.9 EGD90070.2 - 0.41 10.5 3.9 5.5 6.8 0.1 2.6 2 1 0 2 2 2 0 Ubiquitin-activating enzyme active site RNA_pol_A_bac PF01000.26 EGD90071.1 - 3.1e-27 95.2 0.0 5.6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGD90071.1 - 2.9e-19 68.3 0.0 4e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 EGD90072.2 - 1.3e-118 395.0 0.0 4.2e-117 390.1 0.0 2.2 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EGD90072.2 - 0.0075 15.2 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase UQ_con PF00179.26 EGD90073.2 - 1.3e-25 89.7 0.0 1.4e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGD90073.2 - 0.00036 20.2 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGD90073.2 - 0.013 15.8 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain MKT1_N PF12247.8 EGD90074.2 - 5.7e-19 68.3 0.0 1.4e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 EGD90074.2 - 5.9e-06 26.6 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region GIT_SHD PF08518.11 EGD90074.2 - 0.016 14.9 0.2 0.033 13.8 0.2 1.5 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT XPG_N PF00752.17 EGD90074.2 - 0.14 12.7 0.0 0.47 11.0 0.0 1.9 2 0 0 2 2 2 0 XPG N-terminal domain DIOX_N PF14226.6 EGD90075.1 - 1.9e-19 70.6 0.2 2.9e-19 70.0 0.2 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGD90075.1 - 1.5e-12 47.9 0.0 3.4e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-RING_9 PF13901.6 EGD90075.1 - 0.066 13.2 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon 2-Hacid_dh_C PF02826.19 EGD90080.2 - 1.5e-51 174.3 0.0 2.1e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGD90080.2 - 5.5e-15 55.2 0.0 8.7e-15 54.6 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGD90080.2 - 9.4e-08 32.4 0.0 1.5e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGD90080.2 - 0.0013 19.3 0.0 0.003 18.1 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.6 EGD90080.2 - 0.052 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain ApbA PF02558.16 EGD90080.2 - 0.057 13.1 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA CFEM PF05730.11 EGD90081.2 - 6.7e-12 45.3 11.5 1.2e-11 44.5 11.5 1.4 1 0 0 1 1 1 1 CFEM domain Phosducin PF02114.16 EGD90084.1 - 2.2e-15 56.3 0.0 6.9e-15 54.7 0.0 1.8 1 1 0 1 1 1 1 Phosducin YEATS PF03366.16 EGD90085.2 - 1.2e-15 57.2 0.2 3.8e-14 52.4 0.2 2.3 1 1 0 1 1 1 1 YEATS family BET PF17035.5 EGD90085.2 - 2.3e-06 27.7 0.2 3.9e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Ran_BP1 PF00638.18 EGD90086.1 - 5.2e-52 175.3 2.0 9.1e-52 174.5 2.0 1.4 1 0 0 1 1 1 1 RanBP1 domain VID27_PH PF17747.1 EGD90086.1 - 0.00045 20.5 0.1 0.00062 20.0 0.1 1.2 1 0 0 1 1 1 1 VID27 PH-like domain WH1 PF00568.23 EGD90086.1 - 0.0013 18.7 0.4 0.0078 16.1 0.4 2.0 1 1 0 1 1 1 1 WH1 domain LAP1C PF05609.12 EGD90086.1 - 0.26 10.4 10.3 0.3 10.1 10.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC27 PF09507.10 EGD90086.1 - 7.3 5.9 26.1 11 5.3 26.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Tom5 PF10642.9 EGD90086.1 - 8.6 6.5 6.1 0.91 9.6 0.5 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Glyco_transf_15 PF01793.16 EGD90088.1 - 2.5e-95 319.5 13.9 8.1e-95 317.8 13.9 1.7 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PH PF00169.29 EGD90089.1 - 2e-28 98.9 1.5 6.5e-14 52.3 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 EGD90089.1 - 1.4e-12 48.0 4.0 1.8e-07 31.6 0.2 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 EGD90089.1 - 2.7e-07 31.0 7.0 0.0031 17.9 0.2 3.3 2 2 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 EGD90089.1 - 0.00039 20.7 0.0 0.037 14.3 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PBP_N PF17093.5 EGD90089.1 - 0.0062 16.8 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Penicillin-binding protein N-terminus PH_2 PF08458.10 EGD90089.1 - 0.11 12.8 1.8 1.8 9.0 0.1 2.6 3 0 0 3 3 3 0 Plant pleckstrin homology-like region DOT1 PF08123.13 EGD90090.1 - 2.5e-76 255.8 0.0 3.7e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EGD90090.1 - 0.0054 17.4 0.0 0.021 15.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.6 EGD90090.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 EGD90090.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family ATG16 PF08614.11 EGD90091.1 - 1.9e-53 181.7 19.9 2.1e-53 181.5 19.9 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.6 EGD90091.1 - 0.0016 17.6 12.4 0.0016 17.6 12.4 1.4 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region DUF4201 PF13870.6 EGD90091.1 - 0.008 15.9 8.0 0.008 15.9 8.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DUF3786 PF12654.7 EGD90091.1 - 0.022 14.3 0.1 0.084 12.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3786) UPF0242 PF06785.11 EGD90091.1 - 0.039 14.1 2.7 0.039 14.1 2.7 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HAUS-augmin3 PF14932.6 EGD90091.1 - 0.087 12.4 11.1 0.014 15.0 6.5 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF948 PF06103.11 EGD90091.1 - 0.2 11.9 3.4 3.2 8.1 3.4 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 EGD90091.1 - 0.25 10.6 11.1 0.36 10.1 11.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EGD90091.1 - 0.38 9.6 18.3 0.038 12.9 13.7 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 EGD90091.1 - 0.41 10.1 14.0 0.53 9.7 14.0 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 SecD-TM1 PF13721.6 EGD90091.1 - 0.41 11.1 2.5 0.67 10.5 1.2 1.9 1 1 1 2 2 2 0 SecD export protein N-terminal TM region APG6_N PF17675.1 EGD90091.1 - 0.55 10.8 17.3 0.12 12.9 12.7 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Sec2p PF06428.11 EGD90091.1 - 0.79 9.7 14.6 2.2 8.3 12.0 2.5 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p FAM76 PF16046.5 EGD90091.1 - 2.2 7.6 6.8 2.6 7.3 6.8 1.1 1 0 0 1 1 1 0 FAM76 protein Sec34 PF04136.15 EGD90091.1 - 2.3 8.1 8.9 1.7 8.5 0.5 2.7 2 1 1 3 3 3 0 Sec34-like family DHR10 PF18595.1 EGD90091.1 - 3.3 7.8 21.6 1.6 8.8 8.4 2.8 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Laminin_II PF06009.12 EGD90091.1 - 4 7.5 10.7 6.7 6.7 1.8 2.5 2 1 1 3 3 3 0 Laminin Domain II FlgN PF05130.12 EGD90091.1 - 4.9 7.6 15.8 4.8 7.7 13.3 2.1 1 1 1 2 2 2 0 FlgN protein GvpG PF05120.12 EGD90091.1 - 5.7 7.0 10.1 0.18 11.8 2.2 2.4 2 1 1 3 3 2 0 Gas vesicle protein G YabA PF06156.13 EGD90091.1 - 7 7.4 12.5 0.97 10.1 3.7 2.5 2 1 1 3 3 3 0 Initiation control protein YabA DUF4472 PF14739.6 EGD90091.1 - 8 7.3 13.5 6.4 7.6 10.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) HNOBA PF07701.14 EGD90091.1 - 8.8 5.7 9.6 1.2 8.5 2.3 2.3 2 0 0 2 2 2 0 Heme NO binding associated Ras PF00071.22 EGD90092.2 - 3.1e-53 179.7 0.8 1.2e-36 125.7 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 EGD90092.2 - 4.5e-30 104.3 0.2 3e-28 98.5 0.2 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD90092.2 - 2.5e-11 43.4 0.1 1.8e-09 37.3 0.1 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGD90092.2 - 5.9e-09 35.7 0.0 8.3e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGD90092.2 - 9.9e-07 28.8 0.0 1.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGD90092.2 - 4.7e-05 22.8 0.1 7.1e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGD90092.2 - 0.00012 22.1 0.3 0.0034 17.3 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 EGD90092.2 - 0.0052 16.5 0.2 0.16 11.7 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EGD90092.2 - 0.0057 16.0 0.4 0.026 13.8 0.0 2.2 3 0 0 3 3 3 1 Septin AAA_5 PF07728.14 EGD90092.2 - 0.012 15.6 0.1 0.037 14.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGD90092.2 - 0.013 15.8 0.0 0.029 14.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGD90092.2 - 0.017 15.5 0.0 0.025 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EGD90092.2 - 0.018 14.5 0.1 0.036 13.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGD90092.2 - 0.031 14.0 0.5 0.066 12.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGD90092.2 - 0.033 13.8 0.1 0.14 11.7 0.1 2.0 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EGD90092.2 - 0.088 12.7 1.5 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SRPRB PF09439.10 EGD90092.2 - 0.11 11.9 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 EGD90092.2 - 0.11 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 EGD90092.2 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EGD90092.2 - 0.2 12.2 0.3 0.24 11.9 0.3 1.6 1 1 0 1 1 1 0 ABC transporter EamA PF00892.20 EGD90093.2 - 1.1e-11 45.1 36.1 5.2e-08 33.2 4.2 3.1 3 0 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 EGD90093.2 - 2.4e-08 33.6 0.7 2.4e-08 33.6 0.7 1.8 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 EGD90093.2 - 8e-07 28.9 13.7 8e-07 28.9 13.7 1.9 2 0 0 2 2 2 1 Solute carrier family 35 DUF3955 PF13127.6 EGD90093.2 - 0.00024 20.8 0.7 0.00024 20.8 0.7 4.4 6 1 1 7 7 7 1 Protein of unknown function (DUF3955) TPT PF03151.16 EGD90093.2 - 0.0031 16.9 7.1 0.024 14.0 0.2 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF2981 PF11200.8 EGD90093.2 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Spb1_C PF07780.12 EGD90094.2 - 5.4e-85 284.3 18.6 5.4e-85 284.3 18.6 2.3 2 1 1 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 EGD90094.2 - 9.2e-51 171.9 7.7 9.2e-51 171.9 7.7 4.4 5 0 0 5 5 5 2 Domain of unknown function (DUF3381) FtsJ PF01728.19 EGD90094.2 - 1.5e-34 119.7 0.0 2.9e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PcfJ PF14284.6 EGD90094.2 - 3.5 7.5 6.8 0.4 10.5 1.3 2.2 2 0 0 2 2 2 0 PcfJ-like protein Fungal_trans PF04082.18 EGD90096.2 - 0.002 17.2 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_4 PF12763.7 EGD90097.2 - 0.0019 18.1 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.25 EGD90098.1 - 7.5e-70 235.3 0.0 9.3e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90098.1 - 6.3e-33 114.1 0.0 8.5e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGD90098.1 - 1.8e-09 38.1 2.5 4.9e-09 36.8 2.5 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGD90098.1 - 1e-05 24.7 0.1 1.6e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGD90098.1 - 0.043 13.1 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like C2 PF00168.30 EGD90098.1 - 0.069 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 C2 domain FTA2 PF13095.6 EGD90098.1 - 0.073 12.7 0.1 0.83 9.2 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DNA_ligase_A_M PF01068.21 EGD90099.2 - 4.6e-48 163.6 0.0 7.9e-47 159.5 0.0 2.8 3 0 0 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGD90099.2 - 1.6e-31 109.9 0.8 4.7e-31 108.4 0.0 2.2 3 0 0 3 3 3 1 DNA ligase N terminus BRCT_2 PF16589.5 EGD90099.2 - 1e-21 77.1 0.2 2.7e-14 53.4 0.2 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 EGD90099.2 - 1.2e-18 68.0 0.0 3.9e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 RNA ligase DNA_ligase_A_C PF04679.15 EGD90099.2 - 1.3e-17 64.2 0.0 4.5e-17 62.5 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 EGD90099.2 - 3.8e-10 40.0 0.3 3.5e-06 27.3 0.1 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGD90099.2 - 5.8e-08 32.9 1.7 0.0037 17.5 0.0 2.8 2 1 0 2 2 2 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 EGD90099.2 - 0.0054 16.6 0.1 0.72 9.8 0.0 2.4 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain DNA_ligase_IV PF11411.8 EGD90099.2 - 0.0093 16.1 0.2 0.02 15.0 0.2 1.6 1 0 0 1 1 1 1 DNA ligase IV Metallophos PF00149.28 EGD90101.1 - 1.1e-31 110.9 0.0 4.7e-22 79.5 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGD90101.1 - 0.087 13.3 0.1 0.23 11.9 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 EGD90102.2 - 0.038 14.1 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 DUF4646 PF15496.6 EGD90103.2 - 2.7e-19 70.0 0.0 4.5e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) ALG3 PF05208.13 EGD90104.2 - 4.1e-122 408.1 21.5 4.7e-122 407.9 21.5 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.19 EGD90105.1 - 6.3e-20 70.8 0.0 9.1e-20 70.2 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pkinase PF00069.25 EGD90106.2 - 2.7e-60 204.0 0.0 4.3e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90106.2 - 2.8e-35 121.9 0.0 4.9e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 EGD90106.2 - 1.1e-20 73.3 27.8 6.6e-12 45.1 9.0 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EGD90106.2 - 1e-12 48.5 0.4 8.4e-12 45.6 0.7 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 EGD90106.2 - 1.2e-07 32.0 0.0 2.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EGD90106.2 - 0.022 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-RING_9 PF13901.6 EGD90106.2 - 1.8 8.5 22.2 1.3 9.0 7.7 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon TFIIA PF03153.13 EGD90106.2 - 3.8 7.4 31.6 0.57 10.1 27.6 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TFCD_C PF12612.8 EGD90108.1 - 9.9e-36 123.3 0.1 2.1e-35 122.3 0.1 1.6 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EGD90108.1 - 9.2e-06 25.5 0.2 1.8 9.1 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EGD90108.1 - 0.002 18.6 2.9 1.1 9.9 0.0 4.7 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.6 EGD90108.1 - 0.011 16.0 0.4 2.7 8.5 0.1 3.6 3 0 0 3 3 3 0 HEAT repeats IFRD PF05004.13 EGD90108.1 - 0.055 12.6 0.1 0.17 11.0 0.1 1.8 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 EGD90108.1 - 0.067 13.8 0.1 16 6.2 0.0 4.4 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region RsbRD_N PF14361.6 EGD90108.1 - 0.12 13.0 0.1 4.1 8.2 0.0 3.2 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain HEAT_PBS PF03130.16 EGD90108.1 - 0.55 11.1 2.1 30 5.7 0.2 3.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat RRM_1 PF00076.22 EGD90109.1 - 2.9e-27 94.3 1.1 1.9e-12 46.8 0.5 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGD90109.1 - 8.2e-05 22.2 0.0 0.0018 17.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGD90109.1 - 0.0009 19.1 0.0 0.38 10.7 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 EGD90109.1 - 0.017 15.0 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) PHM7_cyt PF14703.6 EGD90109.1 - 0.092 13.0 1.4 5.8 7.1 0.1 3.2 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter SET_assoc PF11767.8 EGD90109.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated ATP-synt_D PF01813.17 EGD90110.1 - 6.7e-71 238.2 0.9 9.7e-71 237.7 0.9 1.2 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.6 EGD90110.1 - 0.0034 17.4 1.5 0.016 15.2 0.5 2.2 2 0 0 2 2 2 1 Synaptonemal complex central element protein 1 HtrL_YibB PF09612.10 EGD90110.1 - 0.049 13.1 0.3 0.077 12.5 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) DUF3919 PF13057.6 EGD90110.1 - 0.063 12.9 0.7 0.093 12.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) TPR_14 PF13428.6 EGD90111.2 - 8.7e-16 57.3 8.6 0.97 10.4 0.0 10.3 8 2 3 11 11 10 3 Tetratricopeptide repeat Suf PF05843.14 EGD90111.2 - 8.5e-11 42.4 9.7 0.052 13.5 0.2 5.8 3 1 2 5 5 5 5 Suppressor of forked protein (Suf) TPR_8 PF13181.6 EGD90111.2 - 3.9e-09 36.0 3.6 0.23 11.7 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGD90111.2 - 5.7e-09 36.4 0.0 0.4 11.2 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGD90111.2 - 9.9e-08 32.2 4.1 20 5.5 0.0 7.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGD90111.2 - 6.2e-07 28.9 2.5 0.00027 20.2 0.3 4.0 4 1 1 5 5 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGD90111.2 - 1.1e-06 28.7 8.4 0.61 10.1 0.1 6.3 5 2 0 6 6 6 1 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 EGD90111.2 - 3.2e-05 23.7 17.4 0.78 10.0 0.0 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGD90111.2 - 0.00024 21.2 2.1 0.9 10.1 0.0 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGD90111.2 - 0.00056 19.6 0.1 3.6 7.6 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGD90111.2 - 0.013 16.1 0.0 97 4.1 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGD90111.2 - 0.025 14.4 9.3 44 4.1 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGD90111.2 - 0.026 14.2 0.0 0.45 10.2 0.0 3.2 4 0 0 4 4 4 0 TPR repeat HAT PF02184.16 EGD90111.2 - 0.034 14.1 8.1 1.5 8.9 0.1 5.8 6 0 0 6 6 5 0 HAT (Half-A-TPR) repeat TPR_7 PF13176.6 EGD90111.2 - 0.093 12.8 2.7 51 4.2 0.0 5.0 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGD90111.2 - 0.11 13.2 3.6 32 5.5 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat PPR PF01535.20 EGD90111.2 - 0.32 11.3 1.8 1e+02 3.5 0.0 4.6 4 0 0 4 4 4 0 PPR repeat Sec7 PF01369.20 EGD90112.2 - 1.3e-60 204.2 0.0 2.1e-60 203.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EGD90112.2 - 1.1e-21 77.3 0.0 3.8e-20 72.4 0.0 2.9 2 1 1 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EGD90112.2 - 0.0033 17.1 0.9 0.0033 17.1 0.9 2.1 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 RhoGEF PF00621.20 EGD90114.1 - 3.9e-19 69.6 0.0 7.4e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 EGD90114.1 - 2.1e-05 24.3 0.0 4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Nod1 PF17114.5 EGD90114.1 - 0.016 15.3 0.0 0.27 11.4 0.0 2.6 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 APG6_N PF17675.1 EGD90114.1 - 4 8.0 9.1 42 4.7 0.1 2.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 EGD90114.1 - 8.5 5.8 7.3 21 4.6 7.3 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_3 PF01171.20 EGD90115.2 - 4.1e-43 147.2 0.0 1.5e-42 145.4 0.0 1.9 1 1 0 1 1 1 1 PP-loop family NAD_synthase PF02540.17 EGD90115.2 - 0.0079 15.3 0.0 0.086 11.9 0.0 2.2 2 0 0 2 2 2 1 NAD synthase Mito_carr PF00153.27 EGD90116.1 - 7e-45 150.9 3.8 8.7e-20 70.5 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 EGD90117.2 - 1.1e-20 73.6 15.5 3.5e-05 24.5 0.3 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD90117.2 - 1.1e-05 25.6 0.3 0.14 12.4 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD90117.2 - 0.0018 17.0 6.4 0.012 14.2 0.6 3.3 2 1 2 4 4 4 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EGD90117.2 - 0.019 13.9 1.6 1.1 8.1 0.4 3.2 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Pkinase PF00069.25 EGD90118.1 - 6e-47 160.2 0.0 3.9e-46 157.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90118.1 - 2.4e-21 76.2 0.0 3.6e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGD90118.1 - 0.0048 16.9 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGD90118.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EGD90118.1 - 0.023 13.6 0.0 0.05 12.5 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EGD90118.1 - 0.094 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L11 PF00298.19 EGD90119.2 - 2.4e-27 95.2 0.1 3.7e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EGD90119.2 - 4e-26 90.6 0.3 6.9e-26 89.9 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Svf1_C PF17187.4 EGD90120.1 - 4.2e-58 195.8 0.0 9.3e-58 194.7 0.0 1.6 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EGD90120.1 - 1.7e-54 184.3 0.0 2.3e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain MFMR PF07777.11 EGD90120.1 - 0.37 11.3 2.6 1.9 9.0 0.0 3.2 3 1 1 4 4 4 0 G-box binding protein MFMR CENP-T_C PF15511.6 EGD90121.2 - 0.0077 16.3 0.0 0.0092 16.1 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AbiEi_4 PF13338.6 EGD90121.2 - 0.0086 16.2 0.8 0.016 15.3 0.4 1.7 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin BP28CT PF08146.12 EGD90121.2 - 0.13 12.1 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 BP28CT (NUC211) domain DUF5368 PF17336.2 EGD90122.1 - 0.0027 17.9 2.5 0.0044 17.2 2.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5368) Acetyltransf_1 PF00583.25 EGD90122.1 - 0.0038 17.5 0.0 0.0057 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.6 EGD90122.1 - 0.027 14.5 0.1 0.057 13.4 0.1 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 EGD90122.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_6 PF12774.7 EGD90124.2 - 1.8e-124 415.0 0.0 1.1e-123 412.5 0.0 2.4 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EGD90124.2 - 3.4e-123 412.2 7.5 3.4e-123 412.2 7.5 3.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EGD90124.2 - 9.9e-116 387.1 3.0 9.9e-116 387.1 3.0 4.1 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EGD90124.2 - 2.1e-74 249.4 1.1 2.1e-74 249.4 1.1 4.5 4 1 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 EGD90124.2 - 4.6e-66 222.8 0.0 1.7e-65 221.0 0.0 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EGD90124.2 - 1.2e-41 142.2 0.0 1.8e-36 125.4 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 EGD90124.2 - 3.7e-39 134.7 7.4 7e-39 133.8 7.4 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGD90124.2 - 3e-32 111.2 0.0 2.2e-27 95.5 0.0 4.4 4 0 0 4 4 4 2 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EGD90124.2 - 3.4e-32 111.3 0.4 1.2e-10 41.5 0.0 6.3 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 EGD90124.2 - 5.6e-27 94.6 0.0 1.4e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 EGD90124.2 - 7.7e-19 68.0 0.1 1.3e-16 60.9 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EGD90124.2 - 1.8e-15 57.4 0.8 0.008 16.4 0.0 7.4 7 0 0 7 7 6 2 AAA domain AAA PF00004.29 EGD90124.2 - 2.1e-14 54.1 0.0 0.0004 20.8 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGD90124.2 - 1.1e-10 42.2 3.0 1.1 9.6 0.0 7.8 7 0 0 7 7 6 2 AAA ATPase domain AAA_33 PF13671.6 EGD90124.2 - 6.6e-10 39.3 3.0 0.091 12.9 0.0 5.5 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.6 EGD90124.2 - 7e-10 39.6 0.8 0.077 13.5 0.0 5.6 5 0 0 5 5 4 2 AAA domain AAA_lid_1 PF17857.1 EGD90124.2 - 9.6e-07 28.9 0.2 0.00013 22.1 0.0 3.5 3 0 0 3 3 2 1 AAA+ lid domain ABC_tran PF00005.27 EGD90124.2 - 1.5e-05 25.5 0.1 1.4 9.5 0.0 5.0 3 0 0 3 3 3 1 ABC transporter T2SSE PF00437.20 EGD90124.2 - 4.6e-05 22.6 0.0 0.034 13.2 0.0 3.0 3 0 0 3 3 2 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 EGD90124.2 - 4.8e-05 22.8 1.0 0.65 9.3 0.0 4.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGD90124.2 - 0.00014 21.9 0.0 1.8 8.6 0.0 4.4 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGD90124.2 - 0.00024 20.9 1.0 38 3.9 0.0 4.8 5 0 0 5 5 4 0 AAA domain AAA_29 PF13555.6 EGD90124.2 - 0.00049 19.8 0.1 2.2 8.1 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGD90124.2 - 0.00064 19.7 0.0 12 5.7 0.0 4.3 4 0 0 4 4 4 0 RsgA GTPase AAA_19 PF13245.6 EGD90124.2 - 0.0018 18.6 2.3 0.27 11.6 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 EGD90124.2 - 0.0026 17.3 0.0 0.32 10.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGD90124.2 - 0.0036 16.6 0.6 1.8 7.8 0.3 4.0 4 0 0 4 4 4 1 Zeta toxin AAA_24 PF13479.6 EGD90124.2 - 0.0037 17.0 0.8 11 5.7 0.0 4.2 4 0 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 EGD90124.2 - 0.0038 17.0 0.8 0.6 9.8 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 EGD90124.2 - 0.0049 16.3 2.8 2 7.7 0.0 4.0 4 0 0 4 4 3 1 FtsK/SpoIIIE family RNA_helicase PF00910.22 EGD90124.2 - 0.0087 16.4 0.1 21 5.5 0.0 4.5 4 0 0 4 4 4 0 RNA helicase Rad17 PF03215.15 EGD90124.2 - 0.0095 15.9 0.2 6.6 6.6 0.0 4.3 5 0 0 5 5 4 0 Rad17 P-loop domain MEDS PF14417.6 EGD90124.2 - 0.19 11.5 3.5 0.18 11.6 0.1 2.9 3 0 0 3 3 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain PduV-EutP PF10662.9 EGD90124.2 - 0.33 10.7 1.7 11 5.7 0.1 4.0 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation DUF4482 PF14818.6 EGD90124.2 - 1.5 9.7 17.8 16 6.3 9.4 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) AAA_17 PF13207.6 EGD90124.2 - 1.6 9.1 6.5 1.4e+02 2.8 0.0 5.0 4 0 0 4 4 4 0 AAA domain Phage_GP20 PF06810.11 EGD90124.2 - 3 7.6 20.8 5.4 6.8 9.8 4.2 3 0 0 3 3 2 0 Phage minor structural protein GP20 NACHT PF05729.12 EGD90124.2 - 8.3 6.3 7.4 31 4.4 0.0 4.2 4 0 0 4 4 3 0 NACHT domain Ribonuclease_3 PF00636.26 EGD90125.1 - 2.7e-41 140.4 0.0 2.1e-19 70.1 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGD90125.1 - 1.2e-23 83.7 0.0 6.5e-12 45.7 0.0 3.3 2 1 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 EGD90125.1 - 8.4e-21 73.9 0.2 1.1e-18 67.1 0.1 2.9 1 1 1 2 2 2 1 Dicer dimerisation domain ResIII PF04851.15 EGD90125.1 - 2.8e-16 60.0 0.3 6.9e-16 58.7 0.3 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGD90125.1 - 1.2e-13 51.4 0.2 5.5e-13 49.2 0.2 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGD90125.1 - 1.2e-09 38.2 0.0 2.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 EGD90125.1 - 0.0047 17.6 0.1 1.4 9.7 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif AAA_22 PF13401.6 EGD90125.1 - 0.076 13.3 0.1 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain TrbI_Ftype PF09677.10 EGD90125.1 - 0.078 13.3 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) TAP42 PF04177.12 EGD90126.1 - 3.5e-107 358.2 4.8 3.9e-107 358.1 4.8 1.0 1 0 0 1 1 1 1 TAP42-like family Lipase_GDSL PF00657.22 EGD90127.2 - 2.6e-10 40.6 0.0 3.3e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EGD90127.2 - 1e-05 26.1 0.0 0.00019 21.9 0.0 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PRP21_like_P PF12230.8 EGD90127.2 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Porphobil_deam PF01379.20 EGD90128.1 - 1.1e-73 247.1 0.1 1.4e-73 246.7 0.1 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EGD90128.1 - 2.9e-18 66.0 0.4 5.1e-18 65.2 0.4 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Lon_C PF05362.13 EGD90129.1 - 2.1e-67 226.6 0.4 4.3e-67 225.6 0.4 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EGD90129.1 - 1.7e-25 90.1 0.1 4.3e-25 88.8 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EGD90129.1 - 4.5e-24 85.4 0.0 3.2e-23 82.6 0.0 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGD90129.1 - 1.1e-07 32.0 0.0 3.7e-07 30.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EGD90129.1 - 1.2e-06 28.4 0.0 2.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EGD90129.1 - 2e-06 28.3 0.1 1.1e-05 26.0 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EGD90129.1 - 6.6e-06 26.0 0.0 1.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EGD90129.1 - 1.8e-05 24.2 0.0 4.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 EGD90129.1 - 6.8e-05 22.7 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGD90129.1 - 0.00035 20.3 0.1 0.0012 18.6 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGD90129.1 - 0.00072 19.7 0.0 0.004 17.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGD90129.1 - 0.001 19.3 0.2 0.01 16.1 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EGD90129.1 - 0.0064 16.7 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Birna_VP4 PF01768.16 EGD90129.1 - 0.0067 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Birnavirus VP4 protein AAA_14 PF13173.6 EGD90129.1 - 0.014 15.5 0.0 0.048 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGD90129.1 - 0.014 15.8 0.0 0.055 13.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 EGD90129.1 - 0.017 15.1 0.1 0.085 12.8 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 EGD90129.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGD90129.1 - 0.023 14.1 0.1 0.059 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EGD90129.1 - 0.026 15.0 0.5 0.24 11.9 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 EGD90129.1 - 0.027 15.0 0.1 0.087 13.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGD90129.1 - 0.036 14.0 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 EGD90129.1 - 0.039 13.4 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_PrkA PF08298.11 EGD90129.1 - 0.042 12.8 0.1 0.18 10.7 0.1 1.9 1 1 0 1 1 1 0 PrkA AAA domain AAA_19 PF13245.6 EGD90129.1 - 0.043 14.2 0.6 0.21 11.9 0.3 2.4 2 1 0 2 2 1 0 AAA domain PhoH PF02562.16 EGD90129.1 - 0.043 13.3 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 EGD90129.1 - 0.05 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EGD90129.1 - 0.058 13.0 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGD90129.1 - 0.074 12.8 0.1 0.074 12.8 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 EGD90129.1 - 0.095 12.4 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGD90129.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGD90129.1 - 0.12 11.5 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 EGD90129.1 - 0.14 11.5 0.1 0.29 10.4 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 EGD90129.1 - 0.15 12.5 0.1 0.15 12.5 0.1 2.9 1 1 1 2 2 1 0 AAA domain Laps PF10169.9 EGD90129.1 - 1 9.9 3.1 4.1 8.0 0.0 2.5 1 1 1 2 2 2 0 Learning-associated protein Ribosomal_L23 PF00276.20 EGD90130.1 - 5.3e-10 39.5 0.0 8.8e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 RIO1 PF01163.22 EGD90131.2 - 1e-32 113.3 0.9 5e-20 71.9 0.1 2.2 2 0 0 2 2 2 2 RIO1 family APH PF01636.23 EGD90131.2 - 1.4e-06 28.4 0.0 0.018 15.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGD90131.2 - 6e-05 22.5 0.0 0.0029 17.0 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SGT1 PF07093.11 EGD90131.2 - 1.1 7.6 5.7 1.4 7.2 5.7 1.1 1 0 0 1 1 1 0 SGT1 protein CDC45 PF02724.14 EGD90131.2 - 1.7 6.9 6.6 2.5 6.3 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Chs7 PF12271.8 EGD90132.1 - 9.9e-123 409.1 15.3 1.1e-122 408.9 15.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 EGD90132.1 - 9.4 6.6 9.5 2.1 8.7 3.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) Ribosomal_L27A PF00828.19 EGD90133.1 - 2.8e-30 105.6 0.4 4.9e-30 104.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A CtnDOT_TraJ PF07863.11 EGD90133.1 - 0.17 12.6 0.1 0.46 11.2 0.1 1.7 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon Pkinase PF00069.25 EGD90135.1 - 9.9e-46 156.2 0.0 1.4e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90135.1 - 1.2e-26 93.6 0.0 4.7e-21 75.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD90135.1 - 0.0042 15.9 0.0 0.0072 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RCC1_2 PF13540.6 EGD90138.1 - 8.4e-14 50.9 7.4 2.5e-07 30.3 0.0 4.5 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 EGD90138.1 - 4.1e-08 33.0 0.1 8.2e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like RCC1 PF00415.18 EGD90138.1 - 0.12 13.0 0.8 4.9 7.9 0.0 3.6 4 1 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat PQ-loop PF04193.14 EGD90139.1 - 2.1e-35 120.3 17.1 2.5e-18 65.6 1.7 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 EGD90139.1 - 0.0027 17.7 9.3 0.016 15.2 0.2 2.9 3 0 0 3 3 3 1 Sugar efflux transporter for intercellular exchange 7TM_GPCR_Srsx PF10320.9 EGD90139.1 - 0.031 13.7 2.4 0.058 12.8 2.4 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2627 PF11118.8 EGD90139.1 - 0.17 12.5 0.3 4.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) Aminotran_1_2 PF00155.21 EGD90140.1 - 1.6e-63 215.1 0.0 2.3e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Tmemb_18A PF09771.9 EGD90140.1 - 0.0024 18.3 0.0 0.0044 17.4 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 188 Beta_elim_lyase PF01212.21 EGD90140.1 - 0.0063 15.8 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase AMP-binding PF00501.28 EGD90141.1 - 9.9e-36 123.2 0.0 1.8e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGD90141.1 - 2e-09 37.2 1.4 7.5e-09 35.4 0.2 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Peptidase_M16_C PF05193.21 EGD90142.1 - 3.5e-50 170.6 0.0 8e-50 169.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGD90142.1 - 7.1e-40 136.4 0.0 1e-38 132.6 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) TRPM_tetra PF16519.5 EGD90142.1 - 0.29 11.3 2.8 0.38 10.9 1.1 2.0 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Abhydrolase_2 PF02230.16 EGD90143.1 - 9.2e-26 91.0 0.0 8.9e-17 61.6 0.0 2.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EGD90143.1 - 0.00027 20.3 0.0 0.0065 15.8 0.0 2.3 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGD90143.1 - 0.0017 17.9 0.0 0.0029 17.1 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGD90143.1 - 0.0077 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 EGD90143.1 - 0.0095 15.6 0.0 0.026 14.2 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EGD90143.1 - 0.021 15.5 0.5 0.035 14.7 0.5 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 EGD90143.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Tom22 PF04281.13 EGD90144.1 - 1.9e-52 176.7 0.7 2.2e-52 176.5 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.6 EGD90145.2 - 3.4e-45 153.6 0.0 1.1e-44 152.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) NPR3 PF03666.13 EGD90145.2 - 0.4 9.4 2.5 0.8 8.4 2.5 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4449 PF14613.6 EGD90146.1 - 1.1e-62 211.0 0.5 1.1e-62 211.0 0.5 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) Peptidase_M2 PF01401.18 EGD90146.1 - 3.8 6.0 11.2 0.088 11.4 3.6 1.8 2 0 0 2 2 2 0 Angiotensin-converting enzyme Peptidase_M35 PF02102.15 EGD90147.2 - 8.5e-73 245.3 0.0 9.4e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EGD90147.2 - 7.7e-35 120.6 0.2 1.2e-34 120.0 0.2 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EGD90147.2 - 0.0014 18.2 0.3 0.067 12.7 0.0 2.2 2 0 0 2 2 2 2 Putative peptidase family Endonuc_subdom PF09062.10 EGD90148.2 - 0.077 13.8 0.0 0.12 13.2 0.0 1.2 1 0 0 1 1 1 0 PI-PfuI Endonuclease subdomain vWA-TerF-like PF10138.9 EGD90149.2 - 3.1e-08 34.0 0.0 4.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Pro-rich PF15240.6 EGD90149.2 - 0.0001 22.7 28.7 0.0001 22.7 28.7 3.4 2 1 1 3 3 3 1 Proline-rich VWA PF00092.28 EGD90149.2 - 0.054 13.7 0.1 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 von Willebrand factor type A domain PhoLip_ATPase_N PF16209.5 EGD90150.2 - 1.1e-24 85.9 0.9 4e-24 84.1 0.3 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EGD90150.2 - 2.8e-11 43.3 0.1 5.9e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase ISN1 PF06437.11 EGD90150.2 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase DUF3573 PF12097.8 EGD90150.2 - 1.2 7.9 3.4 6.5 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) PGP_phosphatase PF09419.10 EGD90154.1 - 2.3e-50 170.5 0.0 2.7e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EGD90154.1 - 2.6e-06 27.4 0.1 4.5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGD90154.1 - 0.00016 22.0 0.1 0.21 11.8 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase TPP_enzyme_M PF00205.22 EGD90154.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain LSM PF01423.22 EGD90155.1 - 3.9e-15 55.3 0.2 5.2e-15 54.9 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGD90155.1 - 0.097 12.8 0.1 0.17 12.0 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Adaptin_binding PF10199.9 EGD90156.2 - 3.6e-18 66.3 3.3 9e-18 65.0 3.3 1.7 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 PTPLA PF04387.14 EGD90157.2 - 1.3e-18 67.3 0.3 1.6e-18 67.0 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA SRP72 PF08492.12 EGD90158.2 - 2.7e-14 53.3 6.3 2.7e-14 53.3 6.3 2.2 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 EGD90158.2 - 0.00076 19.9 0.0 0.002 18.6 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGD90158.2 - 0.082 13.1 0.1 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGD90158.2 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat CBP PF12192.8 EGD90158.2 - 0.13 12.5 1.1 0.25 11.5 0.3 1.9 2 0 0 2 2 2 0 Fungal calcium binding protein Homeobox_KN PF05920.11 EGD90159.1 - 3.7e-20 71.5 0.8 7e-20 70.7 0.8 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EGD90159.1 - 0.00013 21.8 0.2 0.00023 21.0 0.2 1.4 1 0 0 1 1 1 1 Homeodomain FAD_binding_1 PF00667.20 EGD90160.2 - 1.9e-44 151.9 0.0 2.6e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EGD90160.2 - 8e-09 36.1 0.0 2.6e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Med20 PF08612.11 EGD90161.1 - 6.9e-56 189.1 0.0 8.4e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex EF-hand_1 PF00036.32 EGD90162.1 - 1.3e-41 137.0 11.6 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGD90162.1 - 3.6e-36 123.4 5.3 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGD90162.1 - 1.9e-34 117.3 11.5 2.4e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGD90162.1 - 3.8e-30 101.2 8.5 7.1e-09 34.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGD90162.1 - 6.8e-26 88.6 9.8 4.7e-06 25.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGD90162.1 - 1.4e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGD90162.1 - 6.8e-10 38.8 1.6 0.00078 19.4 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGD90162.1 - 5.9e-09 36.2 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EGD90162.1 - 1e-06 28.6 0.1 0.008 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EGD90162.1 - 6.4e-06 26.2 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 EGD90162.1 - 9.4e-05 23.2 0.2 0.0025 18.6 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 EGD90162.1 - 0.00013 21.9 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 EGD90162.1 - 0.00059 19.8 1.6 0.52 10.2 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 EGD90162.1 - 0.00062 20.1 0.7 0.66 10.3 0.1 2.6 2 1 1 3 3 3 2 RNA polymerase Rpb4 Dockerin_1 PF00404.18 EGD90162.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 EGD90162.1 - 0.0057 15.3 0.0 0.0058 15.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 EGD90162.1 - 0.0084 16.0 0.7 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 EGD90162.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 EGD90162.1 - 0.023 14.9 0.0 0.18 12.0 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein RuvA_C PF07499.13 EGD90162.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 EGD90162.1 - 0.061 12.5 0.1 1 8.5 0.1 2.1 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 EGD90162.1 - 0.061 13.5 0.3 0.91 9.7 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF4497 PF14924.6 EGD90162.1 - 0.092 13.2 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RloB PF13707.6 EGD90162.1 - 0.11 12.7 1.3 0.72 10.0 0.2 2.1 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 EGD90162.1 - 0.16 12.1 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) SNARE PF05739.19 EGD90163.1 - 1.4e-14 53.8 1.8 3.3e-14 52.6 1.8 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EGD90163.1 - 0.00027 20.7 8.7 0.00052 19.7 8.7 1.4 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 EGD90163.1 - 0.049 13.4 0.7 0.049 13.4 0.7 2.4 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CTD_bind PF04818.13 EGD90164.2 - 2.2e-17 63.6 0.1 1.1e-16 61.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. YscO-like PF16789.5 EGD90164.2 - 0.022 14.8 1.0 0.049 13.7 1.0 1.5 1 0 0 1 1 1 0 YscO-like protein CTK3 PF12243.8 EGD90164.2 - 0.13 12.3 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 YjcZ PF13990.6 EGD90164.2 - 0.48 9.7 3.2 11 5.3 0.1 2.2 2 0 0 2 2 2 0 YjcZ-like protein CREPT PF16566.5 EGD90164.2 - 0.5 10.5 4.1 0.23 11.6 1.2 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Clathrin_lg_ch PF01086.17 EGD90165.1 - 2.4e-74 250.3 3.4 2.7e-74 250.1 3.4 1.0 1 0 0 1 1 1 1 Clathrin light chain Acyl_transf_3 PF01757.22 EGD90166.2 - 2.7e-06 26.7 34.3 4.7e-06 25.9 34.3 1.4 1 1 0 1 1 1 1 Acyltransferase family Mannosyl_trans3 PF11051.8 EGD90167.2 - 1.5e-55 188.5 0.0 9.5e-32 110.4 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative CDC37_N PF03234.14 EGD90168.2 - 1.6e-50 171.3 2.0 1.6e-50 171.3 2.0 3.2 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EGD90168.2 - 9e-37 125.6 2.2 1.2e-27 96.1 0.1 3.0 3 0 0 3 3 3 2 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EGD90168.2 - 2.6e-35 120.5 3.3 2.6e-35 120.5 3.3 2.2 3 0 0 3 3 3 1 Cdc37 C terminal domain MecA_N PF05223.11 EGD90168.2 - 0.011 16.0 3.1 0.012 15.8 1.2 2.2 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain DUF2680 PF10925.8 EGD90168.2 - 0.66 10.0 4.1 5.6 7.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) ABC_membrane PF00664.23 EGD90169.1 - 1.5e-52 178.9 10.5 2e-52 178.5 10.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGD90169.1 - 3.1e-35 121.7 0.0 9.3e-35 120.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGD90169.1 - 6.2e-07 29.1 0.1 5.1e-05 22.8 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGD90169.1 - 0.00025 21.5 0.7 0.0008 19.8 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGD90169.1 - 0.0031 17.8 0.2 0.021 15.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGD90169.1 - 0.006 16.3 0.5 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 EGD90169.1 - 0.015 15.8 0.0 0.075 13.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EGD90169.1 - 0.031 14.0 0.2 0.5 10.1 0.0 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 EGD90169.1 - 0.043 13.5 0.0 0.14 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGD90169.1 - 0.048 13.2 0.1 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EGD90169.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 EGD90169.1 - 0.12 12.5 0.0 0.59 10.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 EGD90169.1 - 0.13 12.3 0.1 0.89 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EGD90169.1 - 0.21 11.8 1.2 2.5 8.4 0.6 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EGD90169.1 - 0.55 10.7 2.5 0.77 10.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain Nucleoside_tran PF01733.18 EGD90170.1 - 4.3e-41 141.3 15.6 1.4e-39 136.4 11.2 3.1 1 1 1 2 2 2 2 Nucleoside transporter DUF2254 PF10011.9 EGD90170.1 - 0.55 9.0 4.0 0.2 10.4 1.2 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Phage_holin_3_6 PF07332.11 EGD90170.1 - 1.3 9.1 0.0 1.3 9.1 0.0 4.9 3 1 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Ac76 PF05814.11 EGD90170.1 - 1.4 9.0 3.2 0.95 9.5 0.4 2.2 2 0 0 2 2 2 0 Orf76 (Ac76) Metallophos_2 PF12850.7 EGD90172.2 - 5.9e-09 36.3 0.0 3.4e-07 30.6 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGD90172.2 - 7.5e-09 36.4 0.0 1.4e-08 35.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_4 PF07721.14 EGD90172.2 - 0.11 13.2 0.6 0.92 10.3 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Haspin_kinase PF12330.8 EGD90173.1 - 1e-42 146.4 0.0 1.8e-42 145.6 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGD90173.1 - 0.039 13.9 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1682 PF07946.14 EGD90175.1 - 1.1e-112 376.4 1.6 1.3e-112 376.2 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF3619 PF12279.8 EGD90175.1 - 0.019 15.3 0.7 4.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) Glyco_tran_WecB PF03808.13 EGD90175.1 - 0.14 12.1 0.2 0.33 10.9 0.2 1.6 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family COX7a PF02238.15 EGD90176.2 - 5.9e-22 77.8 2.2 7.8e-22 77.4 2.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII PPR_3 PF13812.6 EGD90177.1 - 0.013 15.5 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Pentatricopeptide repeat domain SYF2 PF08231.12 EGD90179.1 - 4.3e-56 189.7 17.8 4.3e-56 189.7 17.8 2.1 2 1 0 2 2 2 1 SYF2 splicing factor ARD PF03079.14 EGD90179.1 - 0.092 12.9 0.6 0.092 12.9 0.6 3.6 2 1 1 3 3 3 0 ARD/ARD' family POT1PC PF16686.5 EGD90179.1 - 0.24 11.3 6.2 0.28 11.0 0.4 2.8 3 0 0 3 3 3 0 ssDNA-binding domain of telomere protection protein Pepsin-I3 PF06394.13 EGD90179.1 - 0.26 11.5 3.0 0.21 11.8 0.4 2.2 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DUF1797 PF08796.10 EGD90179.1 - 1.2 9.3 4.4 0.57 10.3 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) Epimerase PF01370.21 EGD90180.1 - 7.9e-07 28.8 0.0 2e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGD90180.1 - 2.7e-06 27.4 0.0 8.8e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGD90180.1 - 5.4e-05 22.3 0.0 0.00016 20.8 0.0 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EGD90180.1 - 0.00047 19.7 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EGD90180.1 - 0.0038 16.7 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGD90180.1 - 0.0099 15.0 0.0 0.029 13.5 0.0 1.7 3 0 0 3 3 3 1 RmlD substrate binding domain KR PF08659.10 EGD90180.1 - 0.019 14.9 0.0 0.06 13.2 0.0 1.8 2 0 0 2 2 2 0 KR domain Pox_RNA_Pol_19 PF05320.12 EGD90180.1 - 0.031 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit NAD_binding_4 PF07993.12 EGD90180.1 - 0.031 13.4 0.6 1.8 7.7 0.6 3.1 1 1 0 1 1 1 0 Male sterility protein NmrA PF05368.13 EGD90180.1 - 0.04 13.5 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family SMRP1 PF15181.6 EGD90180.1 - 0.078 12.6 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 YEATS PF03366.16 EGD90181.1 - 1.3e-36 124.5 0.7 1.9e-36 123.9 0.7 1.3 1 0 0 1 1 1 1 YEATS family DNA_pol3_delta PF06144.13 EGD90182.2 - 0.0013 18.5 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 EGD90182.2 - 0.002 18.4 0.0 0.0036 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta2 PF13177.6 EGD90182.2 - 0.0026 17.5 0.1 0.004 17.0 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 EGD90182.2 - 0.062 13.7 0.2 0.45 11.0 0.0 2.2 2 1 1 3 3 3 0 Replication factor C C-terminal domain DUF1338 PF07063.13 EGD90184.1 - 9.9e-109 363.4 0.0 1.2e-108 363.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) DUF410 PF04190.13 EGD90186.1 - 4e-88 295.5 0.0 4.7e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RAI1 PF08652.11 EGD90187.2 - 2.4e-26 91.7 0.1 6.3e-26 90.4 0.0 1.8 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease IPPT PF01715.17 EGD90188.2 - 8.7e-62 208.9 0.2 1.4e-61 208.2 0.2 1.3 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 EGD90188.2 - 5.4e-05 22.7 0.2 0.00016 21.1 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 EGD90188.2 - 0.00031 20.9 0.4 0.15 12.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain zf-met PF12874.7 EGD90188.2 - 0.00033 20.9 0.0 0.0006 20.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGD90188.2 - 0.0031 17.8 1.3 0.0075 16.6 0.0 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGD90188.2 - 0.004 17.4 0.0 0.0078 16.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding 7TMR-HDED PF07697.11 EGD90188.2 - 0.0069 16.5 1.5 0.011 15.8 0.6 1.7 1 1 1 2 2 2 1 7TM-HD extracellular AAA_25 PF13481.6 EGD90188.2 - 0.016 14.8 0.4 0.048 13.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGD90188.2 - 0.064 13.8 2.0 1.2 9.7 0.0 3.2 2 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EGD90188.2 - 0.1 13.0 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 EGD90188.2 - 0.12 11.8 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 EGD90188.2 - 0.16 12.3 0.3 0.76 10.1 0.0 2.2 2 1 1 3 3 3 0 AAA ATPase domain DUF3811 PF11656.8 EGD90188.2 - 1.2 9.6 6.6 5 7.6 0.1 3.0 3 0 0 3 3 3 0 YjbD family (DUF3811) DUF87 PF01935.17 EGD90188.2 - 2.9 7.9 7.1 1.3 9.0 0.1 2.9 2 1 1 3 3 3 0 Helicase HerA, central domain ABC_tran PF00005.27 EGD90189.2 - 0.00029 21.4 0.0 0.00047 20.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGD90189.2 - 0.00033 20.6 0.1 0.00053 19.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGD90189.2 - 0.067 12.6 0.0 0.079 12.4 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain FANCF PF11107.8 EGD90189.2 - 0.08 12.1 0.1 0.096 11.9 0.1 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) WD40 PF00400.32 EGD90190.2 - 8.3e-25 86.6 16.6 2.3e-05 25.1 0.0 9.7 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD90190.2 - 3.9e-07 30.3 0.8 22 5.4 0.0 6.4 6 2 2 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain DUF4596 PF15363.6 EGD90190.2 - 0.07 13.4 0.1 0.37 11.1 0.1 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Urm1 PF09138.11 EGD90191.1 - 2.3e-34 117.6 0.0 2.7e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EGD90191.1 - 0.033 14.8 0.0 0.041 14.5 0.0 1.3 1 0 0 1 1 1 0 ThiS family 6PF2K PF01591.18 EGD90192.2 - 2.3e-61 207.0 0.0 3.3e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGD90192.2 - 3.5e-20 72.5 0.0 1.7e-19 70.3 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGD90192.2 - 0.16 12.1 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Porin_3 PF01459.22 EGD90193.1 - 3.7e-80 269.3 0.0 4.3e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 EGD90193.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.25 EGD90195.1 - 6.5e-62 209.3 0.0 7.9e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90195.1 - 4.6e-23 81.8 0.0 6.3e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD90195.1 - 2.8e-05 23.6 0.0 8.6e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGD90195.1 - 0.00043 20.3 0.0 0.017 15.0 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family FA_hydroxylase PF04116.13 EGD90198.1 - 2.3e-25 89.5 18.1 2.7e-25 89.2 15.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily WD40 PF00400.32 EGD90200.2 - 2.3e-15 56.7 4.3 1.1e-05 26.0 0.0 3.2 2 1 0 2 2 2 2 WD domain, G-beta repeat zf-C2H2 PF00096.26 EGD90201.1 - 4.5e-17 61.5 23.3 0.00014 22.1 0.9 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGD90201.1 - 1.7e-14 53.5 22.9 1.7e-07 31.3 2.2 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGD90201.1 - 4.2e-09 36.5 22.7 0.05 14.5 0.6 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EGD90201.1 - 7.4e-05 23.0 1.3 0.061 13.5 0.1 3.0 2 1 1 3 3 3 2 Aberrant zinc-finger zf-met PF12874.7 EGD90201.1 - 0.0011 19.3 7.0 0.3 11.5 0.2 4.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGD90201.1 - 0.26 11.3 10.9 0.23 11.5 0.5 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-LYAR PF08790.11 EGD90201.1 - 0.44 10.5 10.1 9 6.3 0.4 4.5 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 EGD90201.1 - 0.72 10.1 3.1 1.4 9.3 0.6 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain Mito_carr PF00153.27 EGD90202.2 - 4.2e-34 116.4 2.1 3.6e-21 74.9 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Rhabdo_M2 PF04785.12 EGD90202.2 - 0.032 13.6 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 Peptidase_M61 PF05299.12 EGD90202.2 - 0.12 12.8 0.2 0.74 10.2 0.0 2.0 1 1 1 2 2 2 0 M61 glycyl aminopeptidase RRM_1 PF00076.22 EGD90204.1 - 9.9e-35 118.2 0.0 2.1e-16 59.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGD90204.1 - 0.00022 21.3 0.0 0.0056 16.8 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 EGD90204.1 - 0.001 18.7 0.1 0.034 13.7 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGD90204.1 - 0.011 15.8 0.2 0.84 9.8 0.1 2.2 2 0 0 2 2 2 0 Limkain b1 Cas_Cas2CT1978 PF09707.10 EGD90204.1 - 0.014 15.4 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) CMV_1a_C PF12503.8 EGD90204.1 - 0.076 13.0 0.1 17 5.5 0.0 2.3 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein C terminal OB_RNB PF08206.11 EGD90204.1 - 0.11 12.1 0.1 7.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain PHM7_cyt PF14703.6 EGD90204.1 - 0.13 12.5 0.1 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 EGD90204.1 - 0.18 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF2015 PF09435.10 EGD90205.1 - 2.3e-43 146.6 0.0 2.6e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 EGD90206.1 - 2.2e-31 109.0 0.4 3.1e-31 108.5 0.1 1.3 1 1 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.23 EGD90208.2 - 3.4e-44 150.4 0.0 5.3e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EGD90208.2 - 4.8e-42 143.7 0.0 6.6e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 EGD90208.2 - 0.0011 18.0 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF442 PF04273.13 EGD90208.2 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative phosphatase (DUF442) TRAPP PF04051.16 EGD90209.2 - 5.3e-30 104.1 0.0 6.6e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Glyco_transf_90 PF05686.12 EGD90210.1 - 1.9e-18 66.6 7.5 1.8e-13 50.2 4.3 3.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 PINIT PF14324.6 EGD90211.2 - 8.5e-41 139.7 0.1 1.5e-40 138.9 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EGD90211.2 - 2.3e-22 78.5 6.1 7.5e-22 76.8 6.5 1.7 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger SAP PF02037.27 EGD90211.2 - 2.3e-06 27.2 0.6 5.7e-06 26.0 0.6 1.7 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 EGD90211.2 - 7.3e-06 25.7 2.1 1.5e-05 24.7 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit CSTF1_dimer PF16699.5 EGD90211.2 - 0.033 14.0 0.1 0.085 12.6 0.1 1.7 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain zf-Sec23_Sec24 PF04810.15 EGD90211.2 - 0.16 12.1 1.7 0.4 10.8 1.7 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-C3HC4_2 PF13923.6 EGD90211.2 - 4.1 7.3 6.4 9.3 6.2 6.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2423 PF10338.9 EGD90212.1 - 1.6e-20 73.0 0.5 1.6e-20 73.0 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Phosphodiest PF01663.22 EGD90213.1 - 1.2e-13 51.4 1.3 3.5e-07 30.1 0.1 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGD90213.1 - 0.034 13.5 0.0 0.42 10.0 0.0 2.1 2 0 0 2 2 2 0 Sulfatase DUF2567 PF10821.8 EGD90213.1 - 0.28 11.2 5.5 6.6 6.8 1.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2567) Caveolin PF01146.17 EGD90214.1 - 0.037 14.0 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Caveolin RRM_2 PF04059.12 EGD90216.1 - 1.1e-34 118.5 0.6 1.9e-34 117.7 0.6 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EGD90216.1 - 7.6e-09 35.3 0.3 0.048 13.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ins_P5_2-kin PF06090.12 EGD90217.1 - 3.6e-45 154.8 0.0 3.1e-44 151.8 0.0 1.9 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF4444 PF14563.6 EGD90217.1 - 0.047 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) Sec8_exocyst PF04048.14 EGD90218.2 - 0.00017 21.5 3.9 0.00042 20.2 3.9 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 EGD90218.2 - 0.00021 21.4 5.8 0.00066 19.8 5.8 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 PMEI PF04043.15 EGD90218.2 - 0.007 16.7 0.6 0.014 15.7 0.6 1.5 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor COG5 PF10392.9 EGD90218.2 - 0.013 15.7 5.1 0.049 13.8 5.1 2.0 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Vps54_N PF10475.9 EGD90218.2 - 0.017 14.4 6.4 0.028 13.7 6.4 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Sec5 PF15469.6 EGD90218.2 - 0.16 11.8 6.3 0.25 11.1 6.2 1.6 1 1 0 1 1 1 0 Exocyst complex component Sec5 V_ATPase_I PF01496.19 EGD90218.2 - 0.35 8.8 4.8 0.55 8.1 3.9 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family YkyA PF10368.9 EGD90218.2 - 1.6 8.4 8.0 0.23 11.1 3.4 1.9 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein CBFD_NFYB_HMF PF00808.23 EGD90219.2 - 1.3e-12 47.8 0.1 1.9e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGD90219.2 - 4.8e-10 39.9 0.1 7.1e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EGD90219.2 - 0.072 13.4 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Totivirus_coat PF05518.11 EGD90219.2 - 0.86 7.6 6.0 1 7.4 6.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein Fcf2 PF08698.11 EGD90221.1 - 3.7e-38 129.8 0.5 3.7e-38 129.8 0.5 2.0 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Connexin40_C PF16791.5 EGD90221.1 - 0.036 15.3 0.1 0.83 11.0 0.0 2.5 2 0 0 2 2 2 0 Connexin 40 C-terminal domain Ribosomal_S10 PF00338.22 EGD90223.1 - 2.8e-28 98.0 0.0 4.7e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e tRNA-synt_1b PF00579.25 EGD90224.1 - 2.5e-66 224.0 0.0 3.2e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) FAP PF07174.11 EGD90227.1 - 0.14 11.6 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) SWIRM PF04433.17 EGD90229.1 - 3.6e-12 46.4 0.1 1.2e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain CDC50 PF03381.15 EGD90230.1 - 2.2e-79 266.9 0.0 3.5e-79 266.3 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SPT16 PF08644.11 EGD90231.2 - 1.2e-56 191.1 0.1 2.8e-56 189.9 0.1 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 EGD90231.2 - 2.3e-26 92.8 0.0 3.6e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EGD90231.2 - 8.9e-14 51.7 0.1 2.4e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Mito_carr PF00153.27 EGD90232.1 - 1.1e-16 60.5 1.4 2.3e-10 40.3 0.0 3.3 3 1 0 3 3 3 2 Mitochondrial carrier protein GST_N_3 PF13417.6 EGD90234.1 - 8.6e-09 35.7 0.0 1.8e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGD90234.1 - 6.7e-08 32.7 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGD90234.1 - 3.2e-05 24.0 0.0 5.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGD90234.1 - 0.00011 22.1 0.1 0.00022 21.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGD90234.1 - 0.00028 21.0 0.0 0.0006 20.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DBD_Tnp_Hermes PF10683.9 EGD90234.1 - 0.033 13.9 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain PMT PF02366.18 EGD90237.1 - 3.7e-89 298.5 14.7 3.7e-89 298.5 14.7 2.4 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGD90237.1 - 8.8e-65 218.0 17.2 8.8e-65 218.0 17.2 2.1 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGD90237.1 - 3.3e-35 121.6 0.2 5.2e-35 121.0 0.2 1.2 1 0 0 1 1 1 1 MIR domain HKR_ArcB_TM PF18415.1 EGD90237.1 - 1.3 9.8 5.4 0.98 10.3 0.5 3.0 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain Ras PF00071.22 EGD90240.1 - 5.5e-47 159.4 0.1 3e-36 124.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGD90240.1 - 2.2e-28 98.9 0.0 1.2e-17 64.2 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGD90240.1 - 1.3e-08 34.7 0.0 2.4e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 EGD90240.1 - 2.2e-08 33.7 0.1 2.9e-07 30.1 0.1 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGD90240.1 - 2.4e-05 23.8 0.1 0.00013 21.5 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGD90240.1 - 0.00015 21.8 0.1 0.0024 17.9 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGD90240.1 - 0.0025 17.7 0.7 0.37 10.7 0.1 2.4 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EGD90240.1 - 0.099 12.9 1.1 0.74 10.1 0.1 2.5 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 EGD90240.1 - 0.12 12.2 0.1 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FAM176 PF14851.6 EGD90240.1 - 0.14 11.8 3.1 0.22 11.2 3.1 1.2 1 0 0 1 1 1 0 FAM176 family DUF2868 PF11067.8 EGD90240.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) CAP_N PF01213.19 EGD90240.1 - 2.3 7.6 7.4 2.5 7.5 0.2 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Choline_transpo PF04515.12 EGD90242.1 - 2.3e-29 102.6 22.1 2.3e-29 102.6 22.1 2.3 2 0 0 2 2 2 1 Plasma-membrane choline transporter Aldo_ket_red PF00248.21 EGD90245.1 - 3.9e-42 144.5 0.0 8.8e-41 140.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.14 EGD90246.2 - 1.4e-89 301.0 0.0 1.8e-89 300.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family zf-CCHC PF00098.23 EGD90248.2 - 6e-44 146.2 63.3 3.3e-09 36.4 2.0 8.2 8 0 0 8 8 8 7 Zinc knuckle zf-CCHC_4 PF14392.6 EGD90248.2 - 7.7e-11 41.6 45.8 0.0081 15.9 0.7 7.4 8 0 0 8 8 8 7 Zinc knuckle zf-CCHC_5 PF14787.6 EGD90248.2 - 0.046 13.4 42.4 0.84 9.4 0.9 6.8 6 1 1 7 7 7 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EGD90248.2 - 0.067 13.0 1.1 0.067 13.0 1.1 7.0 5 2 2 7 7 7 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGD90248.2 - 0.079 12.9 0.2 0.079 12.9 0.2 7.3 5 2 2 7 7 7 0 Zinc knuckle F-box-like PF12937.7 EGD90249.1 - 9.2e-07 28.7 0.3 2e-06 27.6 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD90249.1 - 1.8e-06 27.7 0.2 3.4e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 EGD90249.1 - 0.093 13.6 0.3 26 5.9 0.2 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat SAE2 PF08573.10 EGD90250.1 - 1.9e-25 90.1 0.0 1.9e-25 90.1 0.0 3.6 4 1 0 4 4 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Cnn_1N PF07989.11 EGD90250.1 - 0.026 14.7 10.0 0.036 14.2 1.8 3.6 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 EGD90250.1 - 0.031 14.8 15.5 0.077 13.5 15.5 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region HOOK PF05622.12 EGD90250.1 - 0.058 11.5 12.0 0.094 10.9 12.0 1.2 1 0 0 1 1 1 0 HOOK protein KASH_CCD PF14662.6 EGD90250.1 - 0.065 13.1 9.2 0.14 11.9 9.2 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 EGD90250.1 - 0.13 11.1 10.4 0.22 10.3 10.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 EGD90250.1 - 0.16 11.7 12.2 0.17 11.7 10.4 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 TMPIT PF07851.13 EGD90250.1 - 0.17 11.1 7.4 0.25 10.6 7.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein TSNAXIP1_N PF15739.5 EGD90250.1 - 0.23 11.8 7.0 0.7 10.3 7.0 1.8 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DivIC PF04977.15 EGD90250.1 - 0.32 10.8 4.0 0.82 9.5 4.0 1.7 1 0 0 1 1 1 0 Septum formation initiator ATG16 PF08614.11 EGD90250.1 - 0.33 11.2 14.0 0.077 13.2 9.2 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 EGD90250.1 - 1.4 8.7 8.4 2.8 7.7 8.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ERM PF00769.19 EGD90250.1 - 1.8 8.3 14.1 0.19 11.6 9.0 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4407 PF14362.6 EGD90250.1 - 4.7 6.5 4.9 10 5.4 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 EGD90250.1 - 7 7.2 13.3 2.7 8.5 0.6 3.0 3 0 0 3 3 3 0 Cell division protein ZapB UPF0242 PF06785.11 EGD90250.1 - 8.5 6.4 10.0 18 5.4 10.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Pex16 PF08610.10 EGD90251.2 - 5.1e-90 301.9 0.0 1.1e-87 294.3 0.0 2.0 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.18 EGD90252.1 - 1.7e-44 152.1 0.0 9.8e-42 143.0 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease HII CENP-C_C PF11699.8 EGD90253.2 - 1.5e-33 114.8 1.5 1.5e-33 114.8 1.5 2.0 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_2 PF07883.11 EGD90253.2 - 2.3e-05 24.0 0.0 6.9e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Cupin domain CAP_GLY PF01302.25 EGD90254.1 - 1.5e-27 95.4 0.0 2.6e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EGD90254.1 - 3.3e-15 56.3 0.0 6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EGD90254.1 - 3.6e-05 23.4 0.0 0.0001 22.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family Methyltransf_11 PF08241.12 EGD90255.1 - 1.7e-12 47.8 0.0 2.7e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD90255.1 - 4.2e-10 40.2 0.0 7.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD90255.1 - 1.8e-07 31.1 0.0 2.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD90255.1 - 1e-06 28.7 0.0 4.5e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD90255.1 - 8.8e-05 23.2 0.0 0.00018 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EGD90255.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Myb_DNA-binding PF00249.31 EGD90257.1 - 5.2e-13 49.0 1.9 4.7e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGD90257.1 - 6.1e-07 29.6 4.3 0.00072 19.7 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain UCH PF00443.29 EGD90261.1 - 1.1e-28 100.4 0.1 1.5e-28 100.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGD90261.1 - 4.1e-16 59.5 6.2 4.3e-15 56.1 6.2 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MitMem_reg PF13012.6 EGD90263.1 - 3.2e-36 124.2 0.2 5.8e-36 123.3 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGD90263.1 - 1.1e-30 106.1 0.0 2.8e-30 104.7 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 EGD90263.1 - 0.029 14.1 4.1 0.039 13.7 4.1 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain ADK PF00406.22 EGD90264.1 - 7.9e-61 204.6 0.1 1e-60 204.2 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGD90264.1 - 4.7e-25 88.6 0.9 9.1e-25 87.7 0.3 1.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 EGD90264.1 - 5.2e-17 61.5 0.0 1.3e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 EGD90264.1 - 5.1e-05 23.5 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGD90264.1 - 0.00026 21.5 0.0 0.00048 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGD90264.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase CFIA_Pcf11 PF11526.8 EGD90266.1 - 2e-11 44.2 1.5 1.4e-10 41.5 1.5 2.5 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 EGD90266.1 - 1.8e-06 28.7 0.0 7.1e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.19 EGD90266.1 - 0.0027 17.5 0.0 0.0091 15.9 0.0 1.8 2 0 0 2 2 2 1 VHS domain zf_UBZ PF18439.1 EGD90266.1 - 1.2 8.8 8.0 4.6 6.9 1.4 2.9 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 EGD90266.1 - 2.2 9.3 3.9 39 5.5 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Inhibitor_I9 PF05922.16 EGD90267.2 - 0.016 15.8 0.1 0.027 15.2 0.1 1.5 1 1 0 1 1 1 0 Peptidase inhibitor I9 Coprogen_oxidas PF01218.18 EGD90269.1 - 1.1e-135 451.1 0.0 1.3e-135 450.8 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.16 EGD90270.1 - 3.1e-51 171.9 0.2 3.6e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EGD90270.1 - 3.4e-06 27.4 0.0 4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Mito_carr PF00153.27 EGD90272.1 - 4.1e-29 100.4 2.7 5.9e-15 55.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Nepo_coat PF03391.15 EGD90273.1 - 0.16 11.4 0.1 0.22 11.0 0.1 1.2 1 0 0 1 1 1 0 Nepovirus coat protein, central domain Apc15p PF05841.11 EGD90274.1 - 9e-12 45.9 0.0 2.4e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Apc15p protein BUD22 PF09073.10 EGD90274.1 - 3.6 6.8 19.2 4.9 6.4 19.2 1.4 1 0 0 1 1 1 0 BUD22 Use1 PF09753.9 EGD90275.1 - 0.0042 16.8 0.0 0.005 16.6 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 CHZ PF09649.10 EGD90276.1 - 2.3e-13 49.4 0.1 2.3e-13 49.4 0.1 2.9 3 0 0 3 3 3 1 Histone chaperone domain CHZ Shugoshin_C PF07557.11 EGD90276.1 - 0.19 11.6 0.1 0.28 11.0 0.1 1.2 1 0 0 1 1 1 0 Shugoshin C terminus CDC27 PF09507.10 EGD90276.1 - 2.9 7.2 10.7 3 7.1 10.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HSP70 PF00012.20 EGD90277.1 - 3.9e-261 867.5 7.8 4.5e-261 867.3 7.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGD90277.1 - 2.5e-16 59.4 0.1 2.1e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGD90277.1 - 0.0032 17.2 0.0 0.01 15.5 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EGD90277.1 - 0.014 15.8 4.4 5.4 7.5 0.0 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 EGD90277.1 - 0.037 13.3 0.1 0.077 12.2 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Fungal_trans PF04082.18 EGD90278.1 - 5.8e-23 81.3 0.8 8.9e-23 80.7 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD90278.1 - 0.013 15.6 13.4 0.022 14.9 13.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAX PF00292.18 EGD90278.1 - 0.14 12.1 0.8 0.33 10.9 0.8 1.5 1 0 0 1 1 1 0 'Paired box' domain DIOX_N PF14226.6 EGD90279.1 - 1.9e-30 106.0 0.0 3.8e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGD90279.1 - 7.5e-18 64.9 0.0 1.5e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GATase_2 PF00310.21 EGD90281.2 - 7.4e-167 555.3 0.0 1e-166 554.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EGD90281.2 - 7.4e-154 512.3 0.0 1.3e-153 511.5 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EGD90281.2 - 4.7e-114 380.6 0.0 5.2e-113 377.2 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EGD90281.2 - 2e-85 285.2 3.5 3.3e-85 284.5 3.5 1.3 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 EGD90281.2 - 3.9e-21 74.9 0.0 8.6e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 EGD90281.2 - 1.5e-17 63.8 0.2 3.4e-17 62.6 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGD90281.2 - 4.8e-09 36.3 0.1 1.8e-08 34.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGD90281.2 - 2e-08 34.7 0.1 1.9e-05 25.1 0.1 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGD90281.2 - 1.4e-07 31.5 1.3 0.0016 18.1 0.5 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EGD90281.2 - 5.6e-07 29.2 0.1 9.4e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EGD90281.2 - 1.7e-05 24.4 0.2 1.7e-05 24.4 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGD90281.2 - 5.6e-05 22.0 0.2 5.6e-05 22.0 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EGD90281.2 - 0.00033 20.0 0.0 0.00068 19.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EGD90281.2 - 0.00037 19.9 1.5 0.029 13.6 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGD90281.2 - 0.0004 19.6 0.4 0.0004 19.6 0.4 1.6 2 0 0 2 2 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EGD90281.2 - 0.0067 15.7 0.2 0.41 9.9 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EGD90281.2 - 0.019 14.1 2.2 0.034 13.2 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 EGD90281.2 - 0.029 13.6 0.2 0.029 13.6 0.2 2.2 3 0 0 3 3 3 0 Thi4 family NAD_binding_7 PF13241.6 EGD90281.2 - 0.033 14.6 1.6 1.9 9.0 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding FMO-like PF00743.19 EGD90281.2 - 0.055 11.9 0.2 0.73 8.2 0.0 2.3 2 1 0 3 3 3 0 Flavin-binding monooxygenase-like AdoHcyase_NAD PF00670.21 EGD90281.2 - 0.077 13.1 0.6 19 5.3 0.0 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Lycopene_cycl PF05834.12 EGD90281.2 - 0.14 11.2 0.2 0.31 10.0 0.2 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Rossmann-like PF10727.9 EGD90281.2 - 0.18 11.7 2.2 1.5 8.7 0.1 2.6 2 0 0 2 2 2 0 Rossmann-like domain DUF3128 PF11326.8 EGD90282.1 - 5.1e-27 94.0 3.7 1e-26 93.1 3.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) RNA12 PF10443.9 EGD90283.1 - 1.2e-157 525.2 1.4 3.3e-156 520.5 1.4 2.2 1 1 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 EGD90283.1 - 0.00023 21.2 0.1 0.0027 17.7 0.1 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2487 PF10673.9 EGD90283.1 - 0.0023 18.0 0.2 0.0078 16.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) RRM_1 PF00076.22 EGD90283.1 - 0.0031 17.3 0.0 0.008 16.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.22 EGD90285.2 - 0.019 13.8 0.0 0.91 8.2 0.0 2.4 2 1 0 2 2 2 0 Cytochrome P450 Mcl1_mid PF12341.8 EGD90286.1 - 6.2e-105 350.8 0.0 1.3e-103 346.5 0.0 2.5 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EGD90286.1 - 1.3e-19 70.2 3.0 7.4e-09 36.1 0.1 7.6 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD90286.1 - 5.5e-18 65.0 0.0 7.9e-05 22.9 0.0 6.8 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGD90286.1 - 6.1e-09 35.4 0.1 1.6e-08 34.0 0.1 1.5 1 1 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.11 EGD90286.1 - 0.00011 22.2 0.2 0.00056 19.9 0.0 2.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 EGD90286.1 - 0.0012 17.3 0.0 0.32 9.3 0.0 2.1 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz DNA_pol_alpha_N PF12254.8 EGD90286.1 - 0.017 15.2 3.2 0.049 13.7 3.2 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal MMS1_N PF10433.9 EGD90286.1 - 0.093 11.3 0.0 0.19 10.3 0.0 1.5 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term TFIIIC_delta PF12657.7 EGD90286.1 - 0.14 12.1 0.1 0.77 9.7 0.0 2.3 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term MMU163 PF17119.5 EGD90287.1 - 4e-113 376.6 0.0 5.1e-113 376.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis MFS_1 PF07690.16 EGD90288.1 - 1.5e-36 126.1 20.4 1.5e-36 126.1 20.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD90288.1 - 5.1e-07 28.9 9.2 8.6e-07 28.2 8.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_5 PF05631.14 EGD90288.1 - 0.0032 16.4 1.5 0.0054 15.7 1.5 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM LacY_symp PF01306.19 EGD90288.1 - 0.017 13.9 0.3 0.033 13.0 0.3 1.4 1 0 0 1 1 1 0 LacY proton/sugar symporter Herpes_UL7 PF01677.16 EGD90289.1 - 0.049 13.4 0.2 0.076 12.7 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL7 like RACo_linker PF17650.1 EGD90289.1 - 0.074 12.9 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 RACo linker region DUF1451 PF07295.11 EGD90289.1 - 0.1 12.6 2.5 0.27 11.3 2.5 1.7 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF2347 PF09804.9 EGD90289.1 - 0.12 12.0 2.3 0.18 11.4 2.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) GRP PF07172.11 EGD90289.1 - 0.39 11.4 21.4 1.6 9.5 21.4 2.1 1 0 0 1 1 1 0 Glycine rich protein family DUF4298 PF14131.6 EGD90289.1 - 1 9.3 8.9 0.44 10.6 4.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) NapD PF03927.13 EGD90289.1 - 1.1 9.4 3.7 1.5 8.9 1.1 2.5 2 0 0 2 2 2 0 NapD protein FAM76 PF16046.5 EGD90289.1 - 2.7 7.3 11.2 3.8 6.8 11.2 1.2 1 0 0 1 1 1 0 FAM76 protein 6PF2K PF01591.18 EGD90292.1 - 2.7e-67 226.3 0.0 2.4e-45 154.5 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGD90292.1 - 1.2e-28 100.1 0.0 4.7e-22 78.6 0.0 2.7 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGD90292.1 - 0.00014 22.0 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF202 PF02656.15 EGD90293.1 - 0.00089 19.7 7.9 0.0061 17.0 7.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF202) Myelin_PLP PF01275.19 EGD90293.1 - 0.043 13.7 0.9 0.053 13.4 0.9 1.1 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) F-box PF00646.33 EGD90294.2 - 5.6e-06 26.1 0.0 5.6e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGD90294.2 - 0.0016 18.3 0.2 0.0034 17.2 0.2 1.5 1 0 0 1 1 1 1 F-box-like FMN_dh PF01070.18 EGD90295.2 - 5.4e-104 348.0 0.0 6.2e-104 347.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EGD90295.2 - 1.5e-07 30.7 0.2 0.00019 20.6 0.0 2.4 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EGD90295.2 - 2e-06 27.2 0.0 4.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EGD90295.2 - 0.0037 16.7 0.4 0.033 13.6 0.1 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 EGD90295.2 - 0.02 14.3 0.0 0.048 13.1 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EGD90295.2 - 0.18 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Sec3_C_2 PF15278.6 EGD90295.2 - 0.2 12.0 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Cauli_VI PF01693.16 EGD90296.2 - 1.8e-38 130.6 7.8 5.6e-20 71.4 0.6 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 EGD90296.2 - 9.2e-37 126.4 0.1 1.7e-36 125.6 0.1 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EGD90296.2 - 0.011 15.6 0.0 0.024 14.4 0.0 1.8 1 1 0 1 1 1 0 Reverse transcriptase-like YmgB PF10798.8 EGD90296.2 - 0.041 13.7 0.3 0.1 12.4 0.3 1.6 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR Na_H_Exchanger PF00999.21 EGD90298.2 - 1.3e-47 162.4 20.5 1.8e-47 162.0 20.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 7TM_GPCR_Srv PF10323.9 EGD90298.2 - 0.17 11.2 3.1 0.13 11.6 1.4 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv GFO_IDH_MocA PF01408.22 EGD90299.2 - 3.4e-13 50.5 0.0 5.3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_23 PF13489.6 EGD90300.2 - 2.9e-08 33.7 0.0 3.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD90300.2 - 0.016 15.0 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGD90300.2 - 0.043 14.6 0.0 0.069 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGD90300.2 - 0.15 12.8 0.0 0.28 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ERG4_ERG24 PF01222.17 EGD90301.2 - 6.4e-107 358.0 13.8 7.9e-107 357.7 13.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ORC6 PF05460.13 EGD90301.2 - 1.6 8.0 4.9 2.9 7.1 4.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-C3HC4 PF00097.25 EGD90302.1 - 1e-05 25.3 9.4 2.1e-05 24.3 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD90302.1 - 2.7e-05 24.1 5.2 2.7e-05 24.1 5.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGD90302.1 - 0.00017 21.9 11.6 0.0031 17.8 5.7 2.4 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 EGD90302.1 - 0.00041 20.2 6.5 0.001 19.0 6.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGD90302.1 - 0.00081 19.2 7.9 0.0019 18.0 7.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGD90302.1 - 0.0022 17.8 6.2 0.0022 17.8 6.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGD90302.1 - 0.0029 17.7 8.8 0.015 15.5 8.9 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGD90302.1 - 2.7 8.3 7.1 14 6.1 7.1 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain UCH PF00443.29 EGD90303.2 - 4.8e-46 157.3 0.0 7.6e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGD90303.2 - 2.2e-15 57.1 0.0 7.2e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DLH PF01738.18 EGD90304.1 - 5.5e-27 94.7 0.0 6.4e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EGD90304.1 - 0.005 16.8 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 EGD90304.1 - 0.022 14.4 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 EGD90304.1 - 0.21 11.1 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Chs7 PF12271.8 EGD90305.1 - 4.4e-108 361.0 6.2 5e-108 360.8 6.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone MpPF26 PF07666.11 EGD90305.1 - 0.011 15.9 2.7 0.011 15.9 2.7 2.8 2 1 0 2 2 2 0 M penetrans paralogue family 26 DUF2569 PF10754.9 EGD90305.1 - 0.018 15.5 15.7 0.034 14.6 6.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) UPF0220 PF05255.11 EGD90305.1 - 0.16 11.5 4.2 0.16 11.5 1.0 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0220) PsbW PF07123.12 EGD90305.1 - 0.24 11.4 1.3 1.4 8.9 0.2 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) EMP70 PF02990.16 EGD90305.1 - 5 5.7 13.0 0.14 10.8 5.5 1.8 2 0 0 2 2 2 0 Endomembrane protein 70 TssN PF17555.2 EGD90305.1 - 9.6 5.5 14.5 0.38 10.1 3.1 2.4 2 1 0 2 2 2 0 Type VI secretion system, TssN Glyoxalase PF00903.25 EGD90306.1 - 5.1e-05 23.5 0.1 0.00013 22.1 0.1 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Importin_rep_6 PF18829.1 EGD90308.1 - 0.16 12.2 1.4 0.31 11.2 0.1 2.0 2 0 0 2 2 2 0 Importin repeat 6 Ge1_WD40 PF16529.5 EGD90308.1 - 0.16 10.9 0.0 0.45 9.4 0.0 1.6 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4239 PF14023.6 EGD90308.1 - 0.24 11.1 1.5 0.59 9.8 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) dCMP_cyt_deam_1 PF00383.23 EGD90309.1 - 7e-05 22.6 0.0 0.00028 20.7 0.0 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF4819 PF16090.5 EGD90309.1 - 0.088 12.9 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4819) Cyclin PF08613.11 EGD90310.1 - 3.5e-29 102.2 2.9 3.5e-29 102.2 2.9 3.5 3 1 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 EGD90310.1 - 0.00049 19.8 0.0 0.00049 19.8 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Arm PF00514.23 EGD90311.2 - 7.5e-11 41.7 12.6 0.0059 16.6 0.5 7.6 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGD90311.2 - 0.062 13.6 15.7 1.7 9.1 0.1 6.5 8 0 0 8 8 8 0 HEAT repeat Fructosamin_kin PF03881.14 EGD90312.2 - 2.2e-60 204.3 0.0 2.9e-59 200.6 0.0 2.0 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EGD90312.2 - 0.00015 21.8 0.0 0.00032 20.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family GST_N_3 PF13417.6 EGD90313.2 - 7.9e-16 58.2 0.1 1.6e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGD90313.2 - 1.8e-15 57.0 0.1 3.7e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGD90313.2 - 1.4e-05 25.4 0.0 3.2e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGD90313.2 - 0.033 14.2 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGD90313.2 - 0.042 14.4 0.0 0.072 13.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGD90313.2 - 0.11 13.3 0.0 0.26 12.1 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain zf-C2H2 PF00096.26 EGD90314.1 - 8.4e-10 38.6 43.4 0.0014 18.9 0.4 9.5 9 0 0 9 9 9 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD90314.1 - 1.1e-08 35.2 44.6 0.11 13.4 0.2 9.3 8 1 1 9 9 9 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGD90314.1 - 7.4e-05 22.9 48.7 0.097 13.0 0.6 9.7 8 2 2 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EGD90314.1 - 0.0056 16.6 0.2 0.0056 16.6 0.2 6.4 6 0 0 6 6 6 2 C2H2-type zinc finger zf-met PF12874.7 EGD90314.1 - 0.24 11.9 32.7 2 9.0 0.1 7.7 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 EGD90314.1 - 0.25 11.2 13.6 4.1 7.3 0.0 4.9 4 1 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 EGD90314.1 - 0.3 11.4 42.8 1.6 9.1 8.3 5.2 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) DUF1477 PF07346.11 EGD90314.1 - 3 8.1 6.4 10 6.4 0.2 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1477) Cyclin_N PF00134.23 EGD90315.1 - 4.8e-09 36.0 0.0 4.3e-07 29.7 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain MRP-S34 PF16053.5 EGD90315.1 - 0.005 16.5 0.1 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S34 CTP_transf_1 PF01148.20 EGD90316.2 - 9.8e-82 274.7 21.8 1.2e-81 274.4 21.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.8 EGD90317.2 - 3.8e-44 150.1 0.0 7.6e-44 149.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 EGD90317.2 - 0.001 17.7 3.5 0.51 8.8 1.8 2.2 2 0 0 2 2 2 2 DNA damage checkpoint protein MAD PF05557.13 EGD90317.2 - 0.0078 14.6 6.1 0.012 14.1 6.1 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF4578 PF15147.6 EGD90317.2 - 0.068 14.1 1.2 0.094 13.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) MOZART1 PF12554.8 EGD90317.2 - 0.076 12.8 0.0 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Peptidase_C65 PF10275.9 EGD90317.2 - 0.21 11.0 1.8 2.5 7.5 0.1 3.0 4 0 0 4 4 4 0 Peptidase C65 Otubain SDA1 PF05285.12 EGD90318.2 - 0.1 12.0 9.3 0.089 12.2 9.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGD90318.2 - 0.15 10.2 9.8 0.13 10.5 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 EGD90318.2 - 0.26 10.8 9.7 0.25 10.9 9.7 1.1 1 0 0 1 1 1 0 PPP4R2 I-EGF_1 PF18372.1 EGD90318.2 - 0.39 10.9 7.2 1.8 8.7 2.3 2.8 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 TFIIA PF03153.13 EGD90318.2 - 1 9.3 11.8 1.1 9.2 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 EGD90318.2 - 6.5 4.9 10.8 7 4.8 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 EGD90318.2 - 9.4 5.5 15.3 14 5.0 15.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FA_desaturase PF00487.24 EGD90319.2 - 1.2e-17 64.6 22.5 1.5e-17 64.3 22.5 1.1 1 0 0 1 1 1 1 Fatty acid desaturase GDPD PF03009.17 EGD90320.1 - 1.2e-16 61.3 0.0 1.7e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family adh_short PF00106.25 EGD90321.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.16 EGD90322.1 - 7.5e-30 104.0 28.9 7.5e-30 104.0 28.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MTS PF05175.14 EGD90324.1 - 8.4e-07 28.7 0.0 5e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGD90324.1 - 8.6e-07 28.9 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD90324.1 - 8.8e-05 23.1 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 EGD90324.1 - 0.00011 21.6 0.0 0.00044 19.7 0.0 1.9 3 0 0 3 3 3 1 RNA methyltransferase PrmC_N PF17827.1 EGD90324.1 - 0.00047 20.7 2.2 0.0019 18.7 0.8 2.8 2 1 0 2 2 2 1 PrmC N-terminal domain PrmA PF06325.13 EGD90324.1 - 0.00078 18.9 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.8 EGD90324.1 - 0.0046 16.5 0.0 0.0072 15.8 0.0 1.4 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Ubie_methyltran PF01209.18 EGD90324.1 - 0.005 16.2 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family N6_Mtase PF02384.16 EGD90324.1 - 0.03 13.6 0.0 0.082 12.2 0.0 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_12 PF08242.12 EGD90324.1 - 0.04 14.6 0.0 0.077 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Asp PF00026.23 EGD90325.1 - 1.6e-65 221.6 0.1 2.1e-65 221.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGD90325.1 - 2.8e-14 53.8 0.9 4.6e-11 43.3 1.5 3.0 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGD90325.1 - 2.9e-05 24.6 0.6 0.39 11.4 0.2 4.2 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EGD90325.1 - 0.0011 19.5 0.1 0.52 10.9 0.0 3.6 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EGD90325.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.6 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal SLX9 PF15341.6 EGD90326.1 - 0.26 11.7 2.1 0.37 11.2 2.1 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Thiamine_BP PF01910.17 EGD90327.2 - 2.2e-31 107.6 0.1 2.5e-31 107.4 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein TPR_12 PF13424.6 EGD90328.1 - 0.0037 17.5 1.6 8.1 6.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGD90328.1 - 0.033 14.7 4.3 4.4 7.9 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGD90328.1 - 0.045 14.6 4.3 7.5 7.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGD90328.1 - 0.076 13.3 3.1 1.5 9.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGD90328.1 - 7.3 7.0 7.7 10 6.5 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_L12 PF00542.19 EGD90330.1 - 6e-22 77.8 8.3 1.6e-20 73.2 6.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EGD90330.1 - 2.7e-12 46.2 18.3 3.8e-12 45.7 10.5 3.4 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 EGD90330.1 - 0.0003 21.3 5.0 0.0003 21.3 5.0 2.2 2 1 0 2 2 2 1 60s Acidic ribosomal protein SpoVIF PF14069.6 EGD90330.1 - 0.095 12.5 3.1 0.2 11.4 0.3 2.5 2 1 0 2 2 2 0 Stage VI sporulation protein F E1_dh PF00676.20 EGD90332.2 - 1.9e-111 371.8 0.1 4.1e-111 370.7 0.1 1.5 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EGD90332.2 - 8.6e-05 21.9 0.1 0.00015 21.1 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase S4 PF01479.25 EGD90335.1 - 3e-15 55.7 0.1 7.1e-15 54.5 0.0 1.7 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.6 EGD90335.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 S4 domain PAP1 PF08601.10 EGD90335.1 - 1.3 8.7 23.8 2 8.1 23.8 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Abhydrolase_1 PF00561.20 EGD90336.2 - 8.7e-09 35.4 0.0 8.7e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD90336.2 - 0.00044 20.9 0.0 0.0005 20.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family APH PF01636.23 EGD90337.1 - 0.00067 19.6 0.5 1.1 9.1 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family AA_permease_2 PF13520.6 EGD90338.1 - 4.5e-63 213.5 43.7 5.8e-63 213.2 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD90338.1 - 2.2e-28 99.1 44.2 3.7e-27 95.1 32.0 2.1 1 1 0 2 2 2 2 Amino acid permease Aminotran_5 PF00266.19 EGD90340.1 - 6.6e-31 107.6 0.0 1.2e-18 67.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aconitase PF00330.20 EGD90341.2 - 9.3e-113 377.6 0.3 7.9e-112 374.6 0.3 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGD90341.2 - 2.3e-23 83.0 0.0 5.3e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF5068 PF16781.5 EGD90341.2 - 0.051 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5068) Peptidase_M22 PF00814.25 EGD90342.1 - 1.8e-83 280.4 0.0 2.4e-83 279.9 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EGD90342.1 - 0.13 11.9 0.1 0.65 9.6 0.1 1.9 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus SET PF00856.28 EGD90343.2 - 2.5e-11 44.3 0.2 7.8e-11 42.6 0.0 1.9 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EGD90343.2 - 4.8e-10 40.2 0.0 1.2e-09 38.9 0.0 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding FAM178 PF14816.6 EGD90343.2 - 0.016 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 EF-hand_1 PF00036.32 EGD90345.2 - 4.4e-27 91.6 12.3 9.4e-08 31.1 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGD90345.2 - 2.7e-22 79.0 12.4 2.3e-13 50.4 1.2 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGD90345.2 - 1.6e-20 71.2 6.0 6.2e-05 22.6 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGD90345.2 - 1.3e-17 62.4 10.6 2.1e-06 27.0 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGD90345.2 - 2.3e-14 52.9 8.2 7.1e-05 22.6 0.1 4.1 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGD90345.2 - 5.9e-06 26.6 0.0 0.01 16.1 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGD90345.2 - 8e-05 22.5 7.8 0.023 14.6 0.3 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGD90345.2 - 0.042 14.2 0.1 0.93 9.9 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain HflK_N PF12221.8 EGD90347.2 - 0.03 14.3 0.1 0.1 12.6 0.1 1.9 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Ribosomal_S9 PF00380.19 EGD90349.1 - 2.3e-38 131.4 1.3 3.6e-38 130.8 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S9/S16 EF1G PF00647.19 EGD90350.1 - 1.7e-48 163.1 0.3 3e-48 162.3 0.3 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EGD90350.1 - 2.9e-12 46.6 0.0 6.2e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGD90350.1 - 3.3e-11 43.4 0.0 8.9e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGD90350.1 - 1.2e-08 35.2 0.0 2.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGD90350.1 - 6.4e-08 32.5 0.0 1.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGD90350.1 - 5.9e-06 26.4 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGD90350.1 - 0.00096 19.4 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.18 EGD90351.1 - 3.4e-27 95.1 2.6 1.6e-26 93.0 2.6 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase RRP36 PF06102.12 EGD90352.1 - 7.4e-43 146.4 37.2 7.4e-43 146.4 37.2 2.5 1 1 1 2 2 2 2 rRNA biogenesis protein RRP36 AMPK1_CBM PF16561.5 EGD90359.1 - 2.3e-30 104.6 0.1 4e-30 103.9 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EGD90359.1 - 2e-25 88.9 1.7 7.6e-25 87.0 1.7 2.1 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CTD PF12815.7 EGD90359.1 - 0.13 12.9 1.7 2.7 8.6 1.7 2.6 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Na_K-ATPase PF00287.18 EGD90360.1 - 0.24 10.5 0.1 0.36 10.0 0.1 1.1 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain PsbY PF06298.11 EGD90360.1 - 0.51 10.3 2.3 1.6 8.7 2.3 1.8 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) Mannosyl_trans3 PF11051.8 EGD90361.1 - 3.2e-59 200.5 0.0 2.9e-33 115.4 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative Glyco_transf_8 PF01501.20 EGD90361.1 - 0.02 14.4 0.2 0.075 12.6 0.0 1.9 1 1 1 2 2 2 0 Glycosyl transferase family 8 ABC1 PF03109.16 EGD90362.2 - 4.7e-34 117.1 0.0 1e-33 116.0 0.0 1.6 1 0 0 1 1 1 1 ABC1 family UreF PF01730.16 EGD90363.1 - 4.9e-23 82.2 1.7 6.3e-23 81.8 1.7 1.2 1 0 0 1 1 1 1 UreF BRE1 PF08647.11 EGD90364.1 - 3.5e-25 87.9 14.5 3.5e-25 87.9 14.5 6.7 4 2 2 6 6 6 2 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 EGD90364.1 - 5.1e-10 39.1 8.1 9.3e-10 38.2 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGD90364.1 - 2.6e-09 36.8 8.5 5.1e-09 35.8 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGD90364.1 - 9.7e-08 31.8 10.8 1.8e-07 30.9 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD90364.1 - 1e-07 31.8 6.4 2.2e-07 30.8 6.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGD90364.1 - 1.1e-07 32.0 9.1 2e-07 31.2 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EGD90364.1 - 2.2e-07 30.6 8.5 4e-07 29.8 8.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGD90364.1 - 2.1e-06 27.6 11.2 3.9e-06 26.7 11.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF745 PF05335.13 EGD90364.1 - 0.0011 18.8 7.1 0.0011 18.8 7.1 5.7 3 2 3 6 6 5 1 Protein of unknown function (DUF745) zf-rbx1 PF12678.7 EGD90364.1 - 0.0015 18.8 5.1 0.0046 17.2 5.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGD90364.1 - 0.0017 18.5 7.0 0.0033 17.5 7.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 EGD90364.1 - 0.017 15.2 5.9 0.036 14.1 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) GP41 PF00517.17 EGD90364.1 - 0.027 14.4 0.1 0.027 14.4 0.1 4.3 4 1 1 5 5 5 0 Retroviral envelope protein zf-RING_10 PF16685.5 EGD90364.1 - 0.031 14.4 7.1 0.079 13.1 7.1 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EGD90364.1 - 0.063 13.1 7.7 0.51 10.2 8.4 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EGD90364.1 - 0.57 10.0 6.0 1.3 8.9 6.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-UDP PF14569.6 EGD90364.1 - 0.69 10.1 4.5 1.7 8.8 4.5 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 EGD90364.1 - 1 9.3 3.8 2 8.3 3.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 EGD90364.1 - 1.3 9.1 6.5 2.8 8.1 6.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 EGD90364.1 - 1.7 8.8 12.8 33 4.7 12.0 2.5 1 1 1 2 2 2 0 FYVE zinc finger HALZ PF02183.18 EGD90364.1 - 2.6 8.4 30.2 4.7 7.5 0.5 6.4 6 0 0 6 6 5 0 Homeobox associated leucine zipper Myb_DNA-bind_4 PF13837.6 EGD90364.1 - 2.6 8.5 11.2 0.44 11.0 0.1 4.0 4 0 0 4 4 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGD90365.1 - 2.6e-28 97.7 0.1 2.6e-28 97.7 0.1 2.5 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EGD90365.1 - 0.00011 22.4 0.0 0.00063 19.9 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Maf PF02545.14 EGD90365.1 - 0.0093 15.8 1.1 0.017 15.0 1.1 1.3 1 0 0 1 1 1 1 Maf-like protein SARAF PF06682.12 EGD90366.2 - 2.3e-86 290.5 10.8 4e-85 286.4 10.8 2.0 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis MMM1 PF10296.9 EGD90367.1 - 1.3e-134 448.4 0.0 1.6e-134 448.2 0.0 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ARD PF03079.14 EGD90368.1 - 6e-48 163.0 0.1 7e-48 162.8 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EGD90368.1 - 5.8e-09 35.5 0.0 9.7e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGD90368.1 - 4.3e-05 23.4 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EGD90368.1 - 0.037 13.6 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Cupin GIDA PF01134.22 EGD90369.2 - 1e-127 426.5 0.0 2.1e-127 425.5 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EGD90369.2 - 1.2e-64 218.3 0.0 1.7e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain DUF3605 PF12239.8 EGD90370.2 - 1.1e-44 152.5 1.2 1.4e-44 152.2 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Sec1 PF00995.23 EGD90371.2 - 3.2e-128 429.5 0.0 3.7e-128 429.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family adh_short PF00106.25 EGD90372.1 - 1.6e-33 115.8 0.0 2.3e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD90372.1 - 7.7e-25 87.8 0.0 1e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD90372.1 - 1.8e-10 41.0 0.0 2.7e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGD90372.1 - 2.3e-07 30.5 0.0 7.3e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGD90372.1 - 0.00057 19.1 0.0 0.00073 18.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGD90372.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGD90372.1 - 0.0026 17.7 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGD90372.1 - 0.019 14.5 0.0 0.044 13.3 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.19 EGD90372.1 - 0.11 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_8 PF13450.6 EGD90373.1 - 3.2e-15 56.1 0.3 4.4e-14 52.5 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGD90373.1 - 2.8e-09 37.0 0.0 2.1e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGD90373.1 - 4.9e-08 32.6 0.1 3.4e-05 23.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGD90373.1 - 5.5e-08 32.5 0.0 2.9e-06 26.9 0.0 2.6 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EGD90373.1 - 4.2e-06 26.1 0.1 7.8e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGD90373.1 - 1.8e-05 24.1 0.0 3.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EGD90373.1 - 1.9e-05 23.5 0.4 0.00016 20.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EGD90373.1 - 8.6e-05 23.0 0.2 0.24 12.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGD90373.1 - 0.00035 20.1 0.0 0.0018 17.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGD90373.1 - 0.0011 19.0 0.3 0.021 14.8 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EGD90373.1 - 0.0023 16.8 0.3 0.0069 15.3 0.0 1.9 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EGD90373.1 - 0.0026 17.1 0.1 0.089 12.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGD90373.1 - 0.022 14.0 0.0 0.068 12.4 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EGD90373.1 - 0.026 13.6 0.1 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EGD90373.1 - 0.067 12.3 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A CAP_assoc_N PF14504.6 EGD90373.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 CAP-associated N-terminal GMC_oxred_N PF00732.19 EGD90373.1 - 0.087 12.2 0.0 11 5.3 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase ApbA PF02558.16 EGD90373.1 - 0.19 11.4 0.0 0.69 9.6 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Tyr-DNA_phospho PF06087.12 EGD90374.2 - 1.3e-56 192.3 0.2 6.1e-44 150.6 0.0 2.1 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase Ribosomal_60s PF00428.19 EGD90374.2 - 0.012 16.2 6.3 0.012 16.2 6.3 2.6 2 1 0 3 3 3 0 60s Acidic ribosomal protein UIM PF02809.20 EGD90374.2 - 1.2 9.3 12.6 0.064 13.2 1.0 3.5 3 0 0 3 3 3 0 Ubiquitin interaction motif CDP-OH_P_transf PF01066.21 EGD90376.1 - 4e-11 43.5 0.1 4e-11 43.5 0.1 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MBOAT PF03062.19 EGD90377.1 - 0.0032 16.9 0.0 0.0091 15.4 0.0 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family CPBP PF02517.16 EGD90380.2 - 9.6e-16 57.9 5.7 9.6e-16 57.9 5.7 1.9 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Suc_Fer-like PF06999.12 EGD90381.2 - 2.3e-56 190.8 0.0 2.7e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like HofP PF10748.9 EGD90381.2 - 0.0073 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 DNA utilization proteins HofP zf-C2H2_2 PF12756.7 EGD90382.2 - 2.1e-20 72.9 9.8 1.5e-19 70.2 5.7 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EGD90382.2 - 0.0038 17.6 0.1 0.011 16.1 0.1 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGD90382.2 - 0.26 12.2 7.6 6.7 7.8 0.0 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger tRNA-synt_1 PF00133.22 EGD90383.2 - 4.3e-50 170.6 0.0 5.8e-30 104.1 0.0 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EGD90383.2 - 8e-38 129.8 0.0 1.3e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EGD90383.2 - 2.7e-29 102.1 2.2 3.8e-22 78.6 0.0 4.5 4 1 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGD90383.2 - 1.2e-13 51.3 0.0 2.6e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGD90383.2 - 6.2e-05 22.5 0.0 0.019 14.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain zf-ribbon_3 PF13248.6 EGD90383.2 - 0.19 11.2 2.8 5.1 6.7 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Cation_ATPase_C PF00689.21 EGD90384.2 - 0.032 14.0 4.6 0.068 12.9 4.6 1.6 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF3397 PF11877.8 EGD90384.2 - 3.1 8.0 6.8 7.6 6.8 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3397) DUF2754 PF10953.8 EGD90384.2 - 3.5 7.9 4.5 7.7 6.8 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) Polysacc_synt_C PF14667.6 EGD90384.2 - 6.5 6.8 13.2 1.9 8.5 8.3 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain 2-Hacid_dh_C PF02826.19 EGD90385.1 - 2.1e-49 167.3 0.0 3.3e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGD90385.1 - 3.4e-16 59.1 0.0 5e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain FH2 PF02181.23 EGD90387.1 - 8.5e-81 271.9 5.0 8.5e-81 271.9 5.0 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EGD90387.1 - 5e-69 231.6 0.5 1.4e-68 230.1 0.0 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGD90387.1 - 5.9e-49 166.3 1.4 3.4e-47 160.6 0.3 2.5 1 1 1 2 2 2 2 Diaphanous FH3 Domain TrmE_N PF10396.9 EGD90390.1 - 8.6e-36 122.8 0.0 2e-35 121.6 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 EGD90390.1 - 9.1e-29 101.1 0.0 3.9e-28 99.0 0.0 1.8 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 EGD90390.1 - 4.1e-18 65.5 0.0 8.6e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGD90390.1 - 4.3e-06 26.3 0.2 3e-05 23.6 0.2 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGD90390.1 - 1.3e-05 25.3 0.1 2.6e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.27 EGD90390.1 - 0.00029 20.4 0.1 0.017 14.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGD90390.1 - 0.011 15.6 0.1 0.94 9.4 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EGD90390.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF5638 PF18688.1 EGD90390.1 - 0.037 14.3 0.1 0.072 13.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5638) ABC_tran PF00005.27 EGD90390.1 - 0.049 14.1 0.2 0.19 12.3 0.1 2.0 1 1 0 1 1 1 0 ABC transporter MCM PF00493.23 EGD90390.1 - 0.071 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Roc PF08477.13 EGD90390.1 - 0.15 12.3 0.0 0.5 10.6 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_3_C PF01915.22 EGD90390.1 - 0.17 11.8 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain RNA_pol_L_2 PF13656.6 EGD90391.1 - 6.9e-34 115.5 0.0 9.3e-34 115.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGD90391.1 - 3.1e-14 52.1 0.0 4.7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.6 EGD90392.2 - 0.00066 20.4 0.1 0.00092 19.9 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGD90392.2 - 0.01 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF5301 PF17225.3 EGD90393.1 - 0.019 15.4 1.4 0.044 14.2 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) Abhydrolase_1 PF00561.20 EGD90394.1 - 2.6e-14 53.5 0.0 1.1e-13 51.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD90394.1 - 2.8e-10 39.9 0.0 1.3e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1749 PF08538.10 EGD90394.1 - 0.05 12.7 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) TRAPPC9-Trs120 PF08626.11 EGD90395.2 - 3.1e-289 962.3 0.0 3.5e-289 962.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF3684 PF12449.8 EGD90396.2 - 0 1419.8 0.0 0 1419.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) RhoGAP PF00620.27 EGD90396.2 - 0.13 12.1 0.7 3.2 7.6 0.0 2.8 2 0 0 2 2 2 0 RhoGAP domain WLM PF08325.10 EGD90396.2 - 0.57 10.2 5.0 0.28 11.3 0.7 2.3 2 0 0 2 2 2 0 WLM domain UPF0767 PF15990.5 EGD90396.2 - 0.9 9.7 2.6 2.7 8.2 2.6 1.8 1 0 0 1 1 1 0 UPF0767 family Pro-kuma_activ PF09286.11 EGD90397.1 - 2.8e-38 131.4 0.2 4.7e-38 130.7 0.2 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGD90397.1 - 0.00034 20.0 0.2 0.0019 17.5 0.0 2.1 2 1 0 2 2 2 1 Subtilase family MATH PF00917.26 EGD90397.1 - 0.15 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 MATH domain Rad33 PF08730.10 EGD90398.1 - 0.13 12.2 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 Rad33 RdRP PF05183.12 EGD90399.1 - 1.4e-178 595.3 0.0 1.7e-178 595.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Lsm_C PF14894.6 EGD90399.1 - 0.12 12.1 0.0 0.62 9.9 0.0 2.2 2 0 0 2 2 2 0 Lsm C-terminal Med6 PF04934.14 EGD90400.1 - 1.8e-39 134.6 0.1 2.5e-39 134.1 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Lysine_decarbox PF03641.14 EGD90401.1 - 1.3e-29 103.0 0.0 1.8e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EGD90401.1 - 0.00084 19.0 1.1 0.0012 18.5 0.1 1.7 2 0 0 2 2 2 1 SLOG cluster4 family LSDAT_prok PF18171.1 EGD90401.1 - 0.041 13.1 0.1 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Proteasome PF00227.26 EGD90402.1 - 8e-49 165.7 0.4 1.2e-48 165.2 0.4 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGD90402.1 - 2.9e-12 46.0 1.1 5e-12 45.3 0.3 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.16 EGD90402.1 - 0.064 13.2 0.6 29 4.6 0.1 3.2 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Vps55 PF04133.14 EGD90403.1 - 2.6e-45 153.2 8.9 2.9e-45 153.0 8.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4231 PF14015.6 EGD90403.1 - 0.59 10.6 0.0 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Sld7_C PF18596.1 EGD90404.2 - 7.1e-11 42.1 0.0 6.4e-10 39.0 0.0 2.3 1 1 0 1 1 1 1 Sld7 C-terminal domain DUF4872 PF16169.5 EGD90404.2 - 0.098 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4872) UPF0220 PF05255.11 EGD90405.1 - 3.1e-69 231.8 4.2 3.5e-69 231.6 4.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) G3P_antiterm PF04309.12 EGD90405.1 - 0.065 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator DUF5337 PF17272.2 EGD90405.1 - 1.5 8.7 4.7 5.3 6.9 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Fes1 PF08609.10 EGD90406.2 - 5.9e-29 100.8 3.0 5.9e-29 100.8 3.0 2.0 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.6 EGD90406.2 - 1e-09 38.7 0.1 3.8e-07 30.5 0.0 2.6 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 EGD90406.2 - 1.8e-09 37.1 0.0 0.00028 20.9 0.0 2.9 3 0 0 3 3 2 2 HEAT repeat HEAT_2 PF13646.6 EGD90406.2 - 1.1e-07 32.1 0.6 3.3e-07 30.6 0.1 1.9 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.23 EGD90406.2 - 3.6e-07 30.0 0.0 0.027 14.5 0.0 2.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGD90406.2 - 1.9e-05 24.8 0.1 4.6e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGD90406.2 - 0.00017 20.3 0.1 0.00045 18.9 0.1 1.7 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 EGD90406.2 - 0.0027 17.1 0.1 0.0032 16.8 0.1 1.2 1 0 0 1 1 1 1 V-ATPase subunit H RICTOR_V PF14668.6 EGD90406.2 - 0.0077 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 SIL1 PF16782.5 EGD90406.2 - 0.0099 15.1 0.0 0.65 9.2 0.0 2.2 1 1 1 2 2 2 2 Nucleotide exchange factor SIL1 TPR_18 PF13512.6 EGD90406.2 - 0.01 16.0 0.2 0.48 10.5 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat V-ATPase_H_C PF11698.8 EGD90406.2 - 0.022 14.9 0.3 0.61 10.2 0.0 2.1 1 1 1 2 2 2 0 V-ATPase subunit H FPL PF09758.9 EGD90406.2 - 0.08 12.9 0.2 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein Actin PF00022.19 EGD90409.1 - 2.5e-132 441.4 0.0 1e-131 439.3 0.0 1.7 1 1 0 1 1 1 1 Actin Glyco_hydro_18 PF00704.28 EGD90410.2 - 1.7e-74 251.4 6.6 2.2e-74 251.0 6.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PhageMin_Tail PF10145.9 EGD90410.2 - 0.031 14.1 0.2 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Phage-related minor tail protein GARS_A PF01071.19 EGD90412.1 - 4.1e-84 281.2 0.2 8.1e-84 280.2 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 EGD90412.1 - 2.1e-36 125.4 0.1 6.7e-36 123.8 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 EGD90412.1 - 1e-35 122.4 0.3 2.2e-34 118.1 0.0 3.0 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EGD90412.1 - 1.4e-26 92.5 0.9 4e-26 91.1 0.9 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EGD90412.1 - 1.8e-14 54.1 1.4 6.7e-14 52.3 1.4 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 EGD90412.1 - 0.00084 19.4 0.0 0.0032 17.5 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 EGD90412.1 - 0.00091 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EGD90412.1 - 0.007 15.9 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 EGD90412.1 - 0.0081 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Pet127 PF08634.10 EGD90413.2 - 3.3e-118 394.1 0.0 4.3e-118 393.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 LRR_6 PF13516.6 EGD90414.1 - 0.35 11.1 7.8 23 5.4 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich repeat Gly_transf_sug PF04488.15 EGD90416.1 - 5e-19 68.7 0.0 9.3e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Abhydrolase_6 PF12697.7 EGD90417.1 - 1.9e-09 38.4 4.8 1.9e-09 38.4 4.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGD90417.1 - 0.00014 21.6 0.0 0.0018 18.0 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Bul1_N PF04425.12 EGD90418.1 - 3e-05 23.0 0.4 6.4e-05 21.9 0.3 1.5 1 1 1 2 2 2 1 Bul1 N terminus Arrestin_N PF00339.29 EGD90418.1 - 0.0005 20.1 0.0 0.0015 18.6 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EGD90418.1 - 0.0056 16.1 0.0 0.012 15.0 0.0 1.5 2 0 0 2 2 2 1 Bul1 C terminus Abhydrolase_3 PF07859.13 EGD90419.1 - 0.00017 21.5 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGD90419.1 - 0.00021 21.0 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EGD90419.1 - 0.00041 19.7 0.0 0.0037 16.6 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 LIP PF03583.14 EGD90419.1 - 0.0014 18.0 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_6 PF12697.7 EGD90419.1 - 0.0017 19.0 1.3 0.0036 17.9 0.4 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGD90419.1 - 0.0024 17.5 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGD90419.1 - 0.0031 17.0 0.0 0.0067 15.9 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family AA_permease PF00324.21 EGD90421.2 - 3.1e-51 174.4 7.7 3.6e-51 174.2 7.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD90421.2 - 4.5e-12 45.5 11.4 5.6e-12 45.2 11.4 1.2 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 EGD90422.2 - 4.6e-30 104.8 54.5 2.9e-21 75.8 31.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD90422.2 - 1.3e-06 27.6 7.8 1.3e-06 27.6 7.8 1.6 1 1 1 2 2 2 1 Sugar (and other) transporter Ycf9 PF01737.17 EGD90422.2 - 6.6 6.7 8.8 27 4.8 0.6 3.6 3 0 0 3 3 3 0 YCF9 p450 PF00067.22 EGD90424.2 - 1.5e-19 70.1 0.0 2.1e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Thioesterase PF00975.20 EGD90425.1 - 5.5e-18 65.9 0.0 1e-17 65.0 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EGD90425.1 - 1.8e-08 35.3 0.0 2.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGD90425.1 - 0.0003 20.5 0.2 0.00051 19.8 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGD90425.1 - 0.0081 16.0 0.0 0.015 15.1 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EGD90425.1 - 0.071 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.25 EGD90427.1 - 7.4e-43 146.8 0.0 1.5e-40 139.2 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Ribonuc_2-5A PF06479.12 EGD90427.1 - 4.2e-40 136.9 0.0 1.2e-39 135.4 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EGD90427.1 - 1.7e-20 73.4 0.0 2.1e-19 69.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 EGD90427.1 - 0.00011 21.9 0.1 0.12 12.4 0.0 3.5 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.14 EGD90427.1 - 0.00071 19.0 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.6 EGD90427.1 - 0.0032 17.1 0.1 0.041 13.4 0.0 2.1 1 1 0 2 2 2 1 PQQ-like domain Pkinase_fungal PF17667.1 EGD90427.1 - 0.004 16.0 0.0 0.004 16.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGD90427.1 - 0.007 15.9 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pro_isomerase PF00160.21 EGD90428.2 - 2.9e-51 173.8 0.1 7.1e-51 172.6 0.1 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EGD90428.2 - 2.9e-07 31.1 0.1 0.27 12.2 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Cpn60_TCP1 PF00118.24 EGD90429.1 - 2.7e-139 465.0 12.5 3.1e-139 464.8 12.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pam17 PF08566.10 EGD90432.2 - 6.3e-66 221.3 0.0 1e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Fungal_trans_2 PF11951.8 EGD90433.2 - 5.9e-55 186.6 0.0 8.9e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD90433.2 - 7.1e-09 35.6 11.4 1.5e-08 34.6 11.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIB PF02201.18 EGD90434.1 - 2.4e-28 97.8 0.1 5.8e-28 96.6 0.0 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 EGD90434.1 - 1.4e-14 53.7 0.1 3.5e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 DEK C terminal domain Mcm10 PF09332.11 EGD90434.1 - 0.0069 15.9 3.2 0.008 15.6 3.2 1.1 1 0 0 1 1 1 1 Mcm10 replication factor CheR_N PF03705.15 EGD90434.1 - 0.025 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain RFXA_RFXANK_bdg PF15289.6 EGD90434.1 - 0.058 13.7 2.4 0.072 13.4 1.0 1.8 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain eIF2A PF08662.11 EGD90435.2 - 4e-36 124.7 5.5 4.4e-34 118.1 1.4 3.8 3 3 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EGD90435.2 - 3.3e-07 30.0 0.0 9.8e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EGD90435.2 - 0.0035 18.1 0.5 0.28 12.1 0.1 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat PRP3 PF08572.10 EGD90435.2 - 0.0058 16.4 0.2 0.015 15.1 0.2 1.7 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DLH PF01738.18 EGD90436.1 - 2.7e-29 102.3 0.0 3e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EGD90436.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EGD90436.1 - 0.085 12.6 0.0 0.74 9.6 0.0 2.2 2 1 1 3 3 3 0 Alpha/beta hydrolase family NmrA PF05368.13 EGD90437.1 - 2.5e-10 40.3 0.0 2.8e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGD90437.1 - 4e-08 33.4 0.0 5.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EGD90437.1 - 0.03 14.6 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peptidase_S10 PF00450.22 EGD90438.2 - 1.3e-57 196.2 0.1 4.1e-39 135.2 0.0 2.1 1 1 1 2 2 2 2 Serine carboxypeptidase Abhydrolase_1 PF00561.20 EGD90439.1 - 2.7e-34 119.0 0.0 3.2e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD90439.1 - 1.3e-16 60.6 0.0 2.4e-16 59.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGD90439.1 - 8.1e-10 39.7 0.2 1.1e-09 39.2 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EGD90439.1 - 2.5e-05 24.3 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 EGD90439.1 - 0.015 15.0 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) AXE1 PF05448.12 EGD90439.1 - 0.043 12.5 0.0 3.8 6.1 0.0 2.5 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase PF00756.20 EGD90439.1 - 0.044 13.4 0.0 0.14 11.7 0.0 1.9 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 EGD90439.1 - 0.084 12.3 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ndr PF03096.14 EGD90439.1 - 0.19 10.4 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Ndr family Fungal_trans PF04082.18 EGD90440.2 - 2.7e-19 69.3 2.4 6.4e-19 68.0 2.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EGD90440.2 - 0.00019 21.7 14.4 0.0021 18.4 1.6 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD90440.2 - 0.0057 17.4 13.9 0.017 15.9 0.8 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger SPX PF03105.19 EGD90440.2 - 2 8.2 9.0 3.4 7.5 9.0 1.4 1 0 0 1 1 1 0 SPX domain RSN1_7TM PF02714.15 EGD90441.1 - 2e-85 286.4 27.1 5.8e-85 284.9 23.3 2.3 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGD90441.1 - 8.2e-44 149.1 1.7 8.2e-44 149.1 1.7 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 EGD90441.1 - 6.5e-27 93.5 0.6 1.8e-26 92.1 0.1 1.9 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 EGD90441.1 - 6.9e-25 88.3 0.1 1.1e-24 87.6 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Rubella_E2 PF05749.11 EGD90441.1 - 0.13 11.7 0.0 0.35 10.3 0.0 1.7 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 MutS_V PF00488.21 EGD90443.1 - 3.7e-62 209.7 0.5 6.4e-62 208.9 0.5 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGD90443.1 - 1.9e-33 116.3 1.7 4.2e-33 115.2 1.7 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EGD90443.1 - 1.5e-11 44.5 0.7 1.6e-10 41.2 0.1 2.6 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 EGD90443.1 - 7e-11 42.5 0.1 1.9e-10 41.2 0.1 1.8 1 0 0 1 1 1 1 MutS domain II HMGL-like PF00682.19 EGD90443.1 - 0.0096 15.5 0.2 0.33 10.5 0.1 2.4 2 0 0 2 2 2 1 HMGL-like RasGEF_N_2 PF14663.6 EGD90443.1 - 0.019 15.4 1.7 8.9 6.8 0.0 3.4 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain AAA_30 PF13604.6 EGD90443.1 - 0.02 14.6 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF3213 PF11491.8 EGD90443.1 - 0.097 12.9 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) AAA_14 PF13173.6 EGD90443.1 - 0.12 12.4 0.0 0.58 10.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EGD90444.1 - 1.1e-59 197.0 31.3 1.6e-11 44.5 0.4 9.3 9 1 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD90444.1 - 5.1e-21 74.8 5.4 0.00028 21.1 0.1 6.0 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD90444.1 - 5.7e-08 31.9 5.1 0.52 8.9 0.0 5.7 5 1 1 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGD90444.1 - 1e-06 28.0 0.0 0.056 12.4 0.0 4.8 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGD90444.1 - 1.2e-06 28.6 0.1 0.053 13.4 0.1 3.5 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 EGD90444.1 - 5.4e-05 23.6 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain DUF4550 PF15084.6 EGD90444.1 - 0.013 15.9 0.1 0.12 12.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) WD40_like PF17005.5 EGD90444.1 - 0.015 14.6 0.0 18 4.5 0.0 4.1 4 2 1 5 5 5 0 WD40-like domain PD40 PF07676.12 EGD90444.1 - 0.021 14.8 0.7 5.5 7.0 0.1 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat FAD_binding_9 PF08021.11 EGD90444.1 - 0.029 14.6 0.0 0.74 10.0 0.0 2.9 3 0 0 3 3 3 0 Siderophore-interacting FAD-binding domain Sec10 PF07393.11 EGD90445.2 - 1.5e-148 496.4 0.1 1.9e-148 496.0 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 EGD90445.2 - 0.0022 17.8 1.3 0.0028 17.5 0.1 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGD90445.2 - 0.0071 16.2 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like RINT1_TIP1 PF04437.13 EGD90445.2 - 0.015 14.2 0.1 0.047 12.6 0.1 1.8 2 0 0 2 2 2 0 RINT-1 / TIP-1 family AAA PF00004.29 EGD90446.2 - 4.7e-09 36.8 0.4 1e-08 35.6 0.2 1.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Las1 PF04031.13 EGD90446.2 - 0.16 12.1 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Las1-like Cytochrom_C1 PF02167.15 EGD90447.1 - 9.9e-93 309.9 0.0 1.2e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family SbcCD_C PF13558.6 EGD90447.1 - 0.003 17.8 0.2 0.0061 16.8 0.2 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Cytochrome_CBB3 PF13442.6 EGD90447.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AIG2_2 PF13772.6 EGD90448.1 - 9.8e-06 25.9 0.0 0.00012 22.4 0.0 2.3 2 0 0 2 2 2 1 AIG2-like family DAHP_synth_1 PF00793.20 EGD90451.1 - 7.7e-103 343.1 0.1 9.6e-103 342.8 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MFS_1 PF07690.16 EGD90452.1 - 7.5e-18 64.6 24.8 7.5e-18 64.6 24.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily RSN1_7TM PF02714.15 EGD90453.1 - 2.5e-81 273.0 21.0 2.5e-81 273.0 21.0 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EGD90453.1 - 3.2e-40 138.2 0.0 4.8e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EGD90453.1 - 1.1e-35 122.8 0.7 1.1e-35 122.8 0.7 2.7 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 EGD90453.1 - 0.0016 17.4 2.3 0.0016 17.4 2.3 2.3 2 0 0 2 2 2 1 Calcium-activated chloride channel DUF4293 PF14126.6 EGD90453.1 - 0.53 10.5 0.0 0.53 10.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) hDGE_amylase PF14701.6 EGD90454.2 - 5.8e-174 579.3 0.0 7.6e-174 578.9 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EGD90454.2 - 1.2e-121 406.3 0.1 2.1e-121 405.5 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EGD90454.2 - 3.5e-84 282.4 0.0 1e-83 280.9 0.0 1.8 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EGD90454.2 - 4.8e-12 45.8 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme NAD_Gly3P_dh_N PF01210.23 EGD90455.2 - 2.6e-45 154.2 0.0 6.2e-45 153.0 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EGD90455.2 - 4.3e-42 143.8 0.1 7.3e-42 143.0 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SLX9 PF15341.6 EGD90456.1 - 1.6e-38 132.1 3.2 1.6e-38 132.1 3.2 1.8 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 Pilin_GH PF16734.5 EGD90456.1 - 0.03 14.6 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 Type IV pilin-like G and H, putative ThiF PF00899.21 EGD90457.2 - 7.2e-23 81.2 0.0 1e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EGD90457.2 - 7.8e-10 39.2 0.0 1.5e-09 38.3 0.0 1.5 2 0 0 2 2 2 1 Rhodanese-like domain DPBB_1 PF03330.18 EGD90458.1 - 1.8e-08 34.6 0.0 3.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EGD90458.1 - 0.074 12.9 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Barwin family PMP1_2 PF08114.11 EGD90459.2 - 0.00094 18.9 2.2 0.00094 18.9 2.2 1.4 1 1 0 1 1 1 1 ATPase proteolipid family DUF4381 PF14316.6 EGD90459.2 - 0.0028 17.9 0.1 0.0035 17.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) NCE101 PF11654.8 EGD90459.2 - 0.013 15.2 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Non-classical export protein 1 5TM-5TMR_LYT PF07694.12 EGD90459.2 - 0.029 13.9 0.2 0.036 13.6 0.2 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Flavi_M PF01004.19 EGD90459.2 - 0.033 14.0 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M SecE PF00584.20 EGD90459.2 - 0.083 12.8 0.3 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Sec61_beta PF03911.16 EGD90459.2 - 0.11 12.6 1.8 0.15 12.1 1.8 1.2 1 0 0 1 1 1 0 Sec61beta family Vma12 PF11712.8 EGD90459.2 - 0.12 12.4 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase NAD_binding_11 PF14833.6 EGD90460.1 - 2.6e-43 147.1 0.2 2.2e-29 102.2 0.1 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EGD90460.1 - 8.5e-36 123.5 0.1 1.5e-35 122.7 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EGD90460.1 - 0.0011 18.9 0.1 0.002 18.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGD90460.1 - 0.037 14.6 0.2 0.1 13.2 0.2 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGD90460.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EGD90460.1 - 0.14 11.8 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F_bP_aldolase PF01116.20 EGD90461.1 - 6.3e-81 271.9 0.0 7.1e-81 271.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Fer2_3 PF13085.6 EGD90462.1 - 1.2e-32 112.1 0.1 2e-32 111.4 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EGD90462.1 - 9.9e-09 35.6 5.7 9.9e-09 35.6 5.7 2.2 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGD90462.1 - 1.7e-07 31.5 6.3 1.7e-07 31.5 6.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGD90462.1 - 8.4e-07 29.0 2.5 8.4e-07 29.0 2.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EGD90462.1 - 0.0021 18.6 4.3 0.0021 18.6 4.3 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EGD90462.1 - 0.0049 16.8 0.4 0.0049 16.8 0.4 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain SF3a60_bindingd PF12108.8 EGD90462.1 - 0.17 11.8 0.2 0.26 11.2 0.2 1.3 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain RTA1 PF04479.13 EGD90463.2 - 1.5e-72 243.6 4.1 1.9e-72 243.2 4.1 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3493 PF11998.8 EGD90463.2 - 0.015 15.4 0.5 0.3 11.3 0.1 2.5 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 CBP_BcsF PF11120.8 EGD90463.2 - 0.025 14.7 0.2 0.067 13.3 0.2 1.7 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF Abhydrolase_9_N PF15420.6 EGD90463.2 - 0.31 11.0 2.2 0.52 10.3 1.8 1.5 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Velvet PF11754.8 EGD90465.1 - 1.2e-89 300.6 0.2 1.2e-89 300.6 0.2 2.1 2 0 0 2 2 2 1 Velvet factor Git3 PF11710.8 EGD90466.1 - 7.9e-26 91.1 6.9 1.6e-25 90.1 6.9 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EGD90466.1 - 7.6e-11 41.9 0.8 3.9e-10 39.6 0.0 2.4 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 EGD90466.1 - 3.9e-05 23.1 5.3 7e-05 22.3 5.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 EGD90466.1 - 0.035 13.3 5.3 0.049 12.8 5.0 1.4 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor TPPK_C PF12555.8 EGD90466.1 - 0.42 10.7 6.2 2.7 8.1 2.4 3.0 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal HhH-GPD PF00730.25 EGD90471.1 - 2.7e-07 31.0 0.0 3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4332 PF14229.6 EGD90471.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Fasciclin PF02469.22 EGD90472.1 - 5.9e-34 117.0 0.1 1.9e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain G_glu_transpept PF01019.21 EGD90473.2 - 2.8e-95 320.0 0.0 3.4e-95 319.8 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase TOBE_2 PF08402.10 EGD90473.2 - 0.18 12.0 0.2 1.3 9.3 0.0 2.4 3 0 0 3 3 3 0 TOBE domain AAA PF00004.29 EGD90475.2 - 2.3e-45 154.3 0.4 8.4e-45 152.4 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGD90475.2 - 3.6e-10 39.6 0.1 2.1e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EGD90475.2 - 7.2e-09 35.8 0.4 2.3e-08 34.1 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGD90475.2 - 4.9e-08 33.3 0.0 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGD90475.2 - 1.4e-07 32.0 0.5 3.9e-05 24.1 0.0 3.0 2 2 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EGD90475.2 - 2.9e-06 26.6 0.0 5.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGD90475.2 - 4.6e-05 23.7 1.2 0.011 16.0 0.1 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EGD90475.2 - 0.00023 21.0 0.0 0.00071 19.3 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EGD90475.2 - 0.00038 20.0 0.0 0.0027 17.2 0.1 2.2 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_3 PF17862.1 EGD90475.2 - 0.0004 20.1 0.0 0.00088 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_28 PF13521.6 EGD90475.2 - 0.00043 20.6 0.0 0.0016 18.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGD90475.2 - 0.00059 20.4 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGD90475.2 - 0.0015 18.6 0.1 0.0057 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EGD90475.2 - 0.0015 18.6 0.0 0.019 14.9 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGD90475.2 - 0.0018 18.6 0.0 0.0042 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EGD90475.2 - 0.0021 17.3 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 EGD90475.2 - 0.0036 17.2 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_3 PF07726.11 EGD90475.2 - 0.0061 16.4 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGD90475.2 - 0.0064 16.2 0.1 0.014 15.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EGD90475.2 - 0.0074 16.2 0.2 0.12 12.3 0.0 2.6 3 0 0 3 3 2 1 NACHT domain Mg_chelatase PF01078.21 EGD90475.2 - 0.0079 15.6 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGD90475.2 - 0.0094 16.1 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EGD90475.2 - 0.011 15.2 0.0 0.52 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 EGD90475.2 - 0.016 14.9 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EGD90475.2 - 0.026 14.3 0.2 0.055 13.2 0.2 1.6 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 EGD90475.2 - 0.045 13.6 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 EGD90475.2 - 0.049 13.6 1.1 0.36 10.7 0.0 2.5 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea ATPase PF06745.13 EGD90475.2 - 0.049 13.0 1.0 0.57 9.5 0.0 2.4 3 0 0 3 3 2 0 KaiC AAA_29 PF13555.6 EGD90475.2 - 0.05 13.4 0.0 0.34 10.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.6 EGD90475.2 - 0.055 13.3 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 EGD90475.2 - 0.081 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activat PF00158.26 EGD90475.2 - 0.081 12.6 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGD90475.2 - 0.085 12.1 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 EGD90475.2 - 0.098 12.2 1.3 0.28 10.8 0.1 2.2 2 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EGD90475.2 - 0.14 12.5 0.1 0.38 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGD90475.2 - 0.16 11.5 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Parvo_NS1 PF01057.17 EGD90475.2 - 0.21 10.6 0.0 0.38 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.23 EGD90476.1 - 1.4e-107 359.8 0.1 1.7e-107 359.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGD90476.1 - 6.7e-15 55.8 1.9 4.2e-12 46.6 1.9 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGD90476.1 - 9.3e-06 26.2 0.4 0.17 12.6 0.0 3.6 3 2 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 EGD90476.1 - 0.0011 18.7 0.0 0.014 15.2 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGD90476.1 - 0.0015 19.0 0.1 3.8 8.1 0.0 3.3 3 2 0 3 3 3 2 gag-polyprotein putative aspartyl protease gp45-slide_C PF09116.10 EGD90476.1 - 0.086 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal Arginase PF00491.21 EGD90480.1 - 3.9e-76 256.2 0.4 4.5e-76 256.0 0.4 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.15 EGD90481.1 - 7.4e-96 320.7 0.0 9.4e-96 320.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EGD90481.1 - 8.7e-24 84.1 0.0 1.6e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 GatB domain POM121 PF15229.6 EGD90481.1 - 0.019 14.6 0.2 0.031 13.9 0.2 1.2 1 0 0 1 1 1 0 POM121 family PikAIV_N PF18605.1 EGD90481.1 - 0.09 12.4 0.0 0.09 12.4 0.0 2.8 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain RdRP_1 PF00680.20 EGD90482.1 - 0.09 11.3 0.4 0.13 10.8 0.4 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase Secretin_N_2 PF07655.13 EGD90483.1 - 6.8 7.3 8.8 0.39 11.3 0.3 2.8 2 1 1 3 3 3 0 Secretin N-terminal domain ECH_1 PF00378.20 EGD90485.1 - 1.9e-41 142.1 0.0 3.5e-41 141.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGD90485.1 - 3e-28 99.3 0.0 4.1e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pox_P21 PF05313.12 EGD90485.1 - 0.23 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein NB-ARC PF00931.22 EGD90486.1 - 2.8e-08 33.3 0.0 4.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EGD90486.1 - 2.3e-06 28.1 0.0 2.1e-05 25.0 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain PGAP1 PF07819.13 EGD90486.1 - 2.5e-06 27.4 0.0 2e-05 24.5 0.0 2.0 1 1 1 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 EGD90486.1 - 2.4e-05 23.9 0.2 7.9e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) AAA_33 PF13671.6 EGD90486.1 - 0.0072 16.5 0.0 0.026 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGD90486.1 - 0.0076 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Abhydrolase_6 PF12697.7 EGD90486.1 - 0.016 15.9 0.1 0.016 15.9 0.1 2.9 2 2 0 2 2 1 0 Alpha/beta hydrolase family AAA_22 PF13401.6 EGD90486.1 - 0.019 15.3 0.0 0.057 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hydrolase_4 PF12146.8 EGD90486.1 - 0.022 14.0 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 NACHT PF05729.12 EGD90486.1 - 0.13 12.2 0.1 0.81 9.6 0.0 2.3 2 1 0 2 2 2 0 NACHT domain ATPase PF06745.13 EGD90486.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 EGD90486.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain FHA PF00498.26 EGD90489.1 - 2.3e-12 47.1 0.0 4.6e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain MFS_1 PF07690.16 EGD90490.2 - 4.2e-10 39.1 5.7 4.6e-10 38.9 5.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 EGD90491.1 - 1.3e-18 67.0 6.5 1.2e-13 50.6 0.9 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DnaJ PF00226.31 EGD90492.1 - 2.9e-08 33.7 0.1 5.7e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain SUKH-4 PF14435.6 EGD90492.1 - 0.11 12.6 0.5 1.2 9.2 0.2 2.1 2 0 0 2 2 2 0 SUKH-4 immunity protein Abhydrolase_3 PF07859.13 EGD90493.2 - 5.6e-32 111.3 0.0 1.1e-30 107.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGD90493.2 - 0.0018 17.2 0.1 0.0085 15.0 0.1 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase DUF3944 PF13099.6 EGD90494.1 - 0.011 15.6 0.8 0.031 14.2 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) SLH PF00395.20 EGD90496.1 - 0.073 13.1 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 S-layer homology domain HMG_box PF00505.19 EGD90498.1 - 1.3e-24 86.4 0.5 2.2e-24 85.7 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGD90498.1 - 1.4e-18 67.2 0.9 2.2e-18 66.6 0.9 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EGD90498.1 - 0.00078 20.0 2.5 0.001 19.6 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 EGD90498.1 - 0.013 15.5 1.1 0.014 15.3 0.1 1.6 2 0 0 2 2 2 0 HMG (high mobility group) box 5 CHDNT PF08073.12 EGD90498.1 - 0.042 13.8 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain p450 PF00067.22 EGD90499.2 - 2.9e-36 125.2 0.0 4.5e-36 124.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 O_Spanin_T7 PF17531.2 EGD90499.2 - 0.095 12.7 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 outer-membrane spanin sub-unit Exostosin PF03016.15 EGD90499.2 - 0.17 11.1 0.2 0.26 10.4 0.2 1.4 1 0 0 1 1 1 0 Exostosin family Homoserine_dh PF00742.19 EGD90500.1 - 1.8e-52 177.7 0.0 2.4e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EGD90500.1 - 2.2e-13 50.9 0.0 6.4e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.6 EGD90501.1 - 1.5e-28 98.9 10.3 1.5e-28 98.9 10.3 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4078) ATG11 PF10377.9 EGD90502.2 - 4.8e-45 152.8 0.0 4.8e-45 152.8 0.0 3.6 4 0 0 4 4 4 1 Autophagy-related protein 11 APG17 PF04108.12 EGD90502.2 - 1.5e-08 34.2 46.3 8.3e-08 31.7 0.0 4.3 4 1 0 4 4 4 2 Autophagy protein Apg17 ERM PF00769.19 EGD90502.2 - 0.00032 20.6 17.4 0.00032 20.6 17.4 5.6 4 1 1 5 5 5 2 Ezrin/radixin/moesin family CENP-H PF05837.12 EGD90503.1 - 8.1e-26 90.6 8.7 8.1e-26 90.6 8.7 2.2 2 0 0 2 2 2 2 Centromere protein H (CENP-H) SOAR PF16533.5 EGD90503.1 - 0.018 15.0 7.6 0.1 12.6 3.3 2.8 1 1 2 3 3 3 0 STIM1 Orai1-activating region Cas_DxTHG PF09455.10 EGD90503.1 - 2.5 7.6 8.0 0.96 9.0 5.3 1.6 1 1 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Pex19 PF04614.12 EGD90505.2 - 8e-61 205.9 15.1 8e-61 205.9 15.1 2.0 1 1 1 2 2 2 1 Pex19 protein family DUF4327 PF14217.6 EGD90505.2 - 0.0025 17.9 0.0 0.0068 16.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4327) Gluconate_2-dh3 PF13618.6 EGD90505.2 - 0.15 12.3 9.2 0.4 10.9 1.3 3.1 1 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 ASF1_hist_chap PF04729.13 EGD90506.1 - 2.5e-74 248.3 0.0 3.7e-74 247.8 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 EGD90506.1 - 2 6.5 23.0 2.6 6.2 23.0 1.0 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 EGD90506.1 - 6.6 6.0 14.1 9.4 5.5 14.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Oxysterol_BP PF01237.18 EGD90508.1 - 7.1e-64 216.0 2.6 1e-61 208.8 2.6 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein POT1 PF02765.17 EGD90508.1 - 0.032 14.0 2.0 0.47 10.3 0.0 3.2 4 0 0 4 4 4 0 Telomeric single stranded DNA binding POT1/CDC13 CUE PF02845.16 EGD90510.1 - 1.9e-10 40.2 0.0 3.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain ELK PF03789.13 EGD90510.1 - 0.058 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 ELK domain UCH PF00443.29 EGD90514.1 - 3.6e-36 125.0 1.1 2.3e-31 109.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGD90514.1 - 8.3e-12 45.3 1.4 7.6e-11 42.2 1.3 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_4 PF13717.6 EGD90514.1 - 1.1 9.3 7.3 4.9 7.2 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain F_bP_aldolase PF01116.20 EGD90516.1 - 1.7e-90 303.3 0.0 1.9e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II RSN1_7TM PF02714.15 EGD90518.1 - 2.5e-77 259.9 23.0 4e-77 259.2 23.0 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EGD90518.1 - 1.5e-42 145.8 0.0 2.3e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EGD90518.1 - 4.3e-39 133.8 0.8 4.3e-39 133.8 0.8 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3445 PF11927.8 EGD90521.2 - 1.7e-59 201.2 0.0 2.4e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Pkinase PF00069.25 EGD90524.2 - 1.6e-08 34.2 0.2 2.4e-08 33.7 0.2 1.3 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90524.2 - 0.01 15.2 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase peroxidase PF00141.23 EGD90526.2 - 1.6e-42 145.7 0.0 2.7e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase ERG2_Sigma1R PF04622.12 EGD90527.2 - 2.3e-55 187.2 0.2 2.5e-55 187.0 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein zf-CSL PF05207.13 EGD90528.1 - 1.5e-18 66.2 1.0 2.7e-18 65.4 1.0 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EGD90528.1 - 5.8e-13 48.8 0.2 3.9e-08 33.3 0.1 2.3 2 0 0 2 2 2 2 DnaJ domain PITH PF06201.13 EGD90529.1 - 6.5e-35 120.6 0.0 9.2e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EGD90529.1 - 3.2e-24 84.9 0.0 6.5e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGD90529.1 - 0.00013 22.2 0.0 0.0011 19.2 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGD90529.1 - 0.00017 22.0 0.1 0.00061 20.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EGD90529.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EGD90529.1 - 0.0028 17.1 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGD90529.1 - 0.0056 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EGD90529.1 - 0.037 13.8 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Phosducin PF02114.16 EGD90529.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosducin zf-C2H2 PF00096.26 EGD90531.1 - 2.8e-12 46.4 13.1 1.4e-06 28.4 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD90531.1 - 2.9e-07 30.8 10.7 0.0063 17.3 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGD90531.1 - 1.9e-06 28.0 3.2 0.012 15.9 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EGD90531.1 - 3.8e-06 27.1 3.5 3.8e-06 27.1 3.5 3.7 4 0 0 4 4 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGD90531.1 - 0.00041 20.3 9.0 0.02 14.9 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EGD90531.1 - 0.0013 19.1 10.2 0.0081 16.5 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-LYAR PF08790.11 EGD90531.1 - 0.0052 16.7 3.5 0.19 11.6 0.5 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-UBR PF02207.20 EGD90531.1 - 0.12 12.6 0.7 0.28 11.4 0.7 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf_UBZ PF18439.1 EGD90531.1 - 0.31 10.7 1.9 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 EGD90531.1 - 0.31 10.7 7.8 1.3 8.8 0.4 3.2 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 EGD90531.1 - 0.35 11.2 4.1 10 6.6 0.4 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 EGD90531.1 - 0.68 10.6 5.3 6.3 7.5 0.7 3.2 2 1 1 3 3 2 0 Zinc finger C2H2-type, 3 repeats zf-trcl PF13451.6 EGD90531.1 - 0.78 9.7 4.2 0.83 9.6 0.6 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 EGD90531.1 - 0.85 9.4 8.5 7.3 6.4 0.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 EGD90531.1 - 2 8.5 5.1 1.2 9.3 1.4 2.3 1 1 1 2 2 2 0 BED zinc finger DUF629 PF04780.12 EGD90531.1 - 2.6 6.5 4.5 13 4.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Zn-ribbon_8 PF09723.10 EGD90531.1 - 2.8 8.1 4.4 6.6 6.9 0.6 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2HE PF16278.5 EGD90531.1 - 5.5 7.5 6.8 5.5e+02 1.1 7.0 2.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger DTHCT PF08070.11 EGD90531.1 - 7.9 7.3 13.4 17 6.2 0.6 3.3 2 1 1 3 3 3 0 DTHCT (NUC029) region Diphthami_syn_2 PF01902.17 EGD90532.1 - 4.6e-19 68.8 0.0 1.2e-05 25.0 0.0 4.2 3 1 0 3 3 3 3 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EGD90532.1 - 1.2e-11 44.7 0.0 3e-05 24.0 0.0 3.7 3 1 0 3 3 3 2 Endoribonuclease L-PSP DUF3543 PF12063.8 EGD90538.2 - 1.9e-89 299.3 0.0 3.7e-89 298.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EGD90538.2 - 9.8e-51 172.6 0.0 2.2e-50 171.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90538.2 - 1.1e-35 123.2 0.0 2.8e-35 121.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGD90538.2 - 0.033 14.1 0.8 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family AA_permease_2 PF13520.6 EGD90539.2 - 8.3e-09 34.8 10.6 1.1e-08 34.3 10.6 1.2 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 EGD90539.2 - 0.023 13.7 5.1 0.03 13.4 5.1 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family AA_permease PF00324.21 EGD90539.2 - 0.048 12.3 11.2 0.012 14.2 8.1 1.5 2 0 0 2 2 2 0 Amino acid permease PsbN PF02468.15 EGD90539.2 - 0.053 13.4 1.5 0.053 13.4 1.5 2.1 1 1 1 2 2 2 0 Photosystem II reaction centre N protein (psbN) Aa_trans PF01490.18 EGD90539.2 - 0.18 10.5 7.5 0.32 9.6 7.5 1.5 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein ERAP1_C PF11838.8 EGD90540.2 - 3.2e-87 293.0 0.4 3.9e-85 286.2 0.1 2.5 2 0 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EGD90540.2 - 1.8e-84 282.7 2.8 3.1e-84 281.9 2.8 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EGD90540.2 - 2.2e-52 178.0 1.7 4.3e-52 177.0 1.7 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DEAD PF00270.29 EGD90541.1 - 3.3e-46 157.3 0.0 1.2e-45 155.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD90541.1 - 4.4e-30 104.3 0.1 2e-29 102.2 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD90541.1 - 0.0071 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PRAI PF00697.22 EGD90541.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF2986 PF11661.8 EGD90541.1 - 2.3 8.8 10.0 0.13 12.8 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) UPF0164 PF03687.13 EGD90542.2 - 0.033 13.0 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) p450 PF00067.22 EGD90543.1 - 6.2e-22 78.0 0.1 1.9e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 FAD_binding_4 PF01565.23 EGD90544.1 - 4.3e-20 71.9 3.6 1.4e-19 70.3 3.6 1.9 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGD90544.1 - 0.16 12.1 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like PNPase_C PF12111.8 EGD90544.1 - 3.6 7.1 6.5 7.4 6.1 4.2 2.3 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal Suf PF05843.14 EGD90546.1 - 0.00062 19.8 5.3 0.00071 19.7 0.2 2.8 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EGD90546.1 - 0.0082 16.9 0.4 0.0082 16.9 0.4 6.8 8 1 1 9 9 9 1 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 EGD90546.1 - 0.011 16.0 1.4 1.6 9.0 0.0 3.4 2 1 0 2 2 2 0 c-SKI Smad4 binding domain FAT PF02259.23 EGD90546.1 - 0.037 13.2 0.2 0.25 10.5 0.0 2.3 1 1 1 3 3 3 0 FAT domain DUF4810 PF16068.5 EGD90546.1 - 0.052 14.1 0.1 4 8.1 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4810) TPR_19 PF14559.6 EGD90546.1 - 0.11 13.0 0.4 44 4.7 0.0 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat Mitoc_mL59 PF18126.1 EGD90547.1 - 2.5e-49 166.9 1.4 4.8e-49 166.0 1.4 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 MOSC PF03473.17 EGD90548.1 - 5.2e-30 104.2 0.0 1e-29 103.2 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EGD90548.1 - 5.3e-25 87.6 0.0 1e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 EGD90548.1 - 1.5e-23 83.4 0.0 2.1e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Trypsin PF00089.26 EGD90550.1 - 0.13 12.1 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 Trypsin PAP2 PF01569.21 EGD90551.1 - 2.4e-28 98.6 0.1 2.4e-28 98.6 0.1 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EGD90551.1 - 0.0023 17.6 0.3 0.0092 15.7 0.3 2.0 1 1 0 1 1 1 1 PAP2 superfamily Git3 PF11710.8 EGD90551.1 - 0.17 11.6 1.8 2.8 7.7 0.3 2.7 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 But2 PF09792.9 EGD90553.1 - 3.1e-47 160.6 0.1 4.2e-47 160.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF5640 PF18692.1 EGD90553.1 - 0.19 11.8 0.1 0.99 9.5 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5640) Lactamase_B PF00753.27 EGD90554.1 - 2.6e-05 24.3 0.2 4.2e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Gpr1_Fun34_YaaH PF01184.19 EGD90557.1 - 1.6e-48 165.1 13.4 2.5e-48 164.4 13.4 1.2 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family YrhC PF14143.6 EGD90557.1 - 0.023 14.7 4.5 0.059 13.5 4.5 1.7 1 0 0 1 1 1 0 YrhC-like protein p450 PF00067.22 EGD90558.2 - 3.5e-26 92.0 2.2 1.4e-19 70.2 1.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 TFIIE_alpha PF02002.17 EGD90558.2 - 0.083 12.8 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 TFIIE alpha subunit Pkinase PF00069.25 EGD90559.1 - 3.1e-39 135.0 0.0 1.2e-38 133.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90559.1 - 4e-28 98.4 0.0 5.8e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD90559.1 - 0.0009 18.1 0.0 0.0013 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGD90559.1 - 0.075 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGD90559.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prefoldin_3 PF13758.6 EGD90560.1 - 7.9e-33 112.5 0.5 2.1e-32 111.1 0.1 2.0 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 EGD90560.1 - 4.2e-26 91.6 9.7 8.6e-24 84.2 0.3 3.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3835) MerR-DNA-bind PF09278.11 EGD90560.1 - 0.08 13.5 0.4 21 5.7 0.0 3.1 2 0 0 2 2 2 0 MerR, DNA binding Lzipper-MIP1 PF14389.6 EGD90560.1 - 0.26 11.6 5.7 8.2 6.8 0.3 3.7 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Prefoldin_2 PF01920.20 EGD90560.1 - 0.92 9.5 5.3 5.1 7.1 0.0 3.4 4 0 0 4 4 4 0 Prefoldin subunit Zip PF02535.22 EGD90561.1 - 4.5e-40 137.9 24.4 4.5e-40 137.9 24.4 2.4 2 1 0 2 2 2 1 ZIP Zinc transporter MAT1 PF06391.13 EGD90563.1 - 6.9e-42 143.6 17.4 9.1e-42 143.2 17.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EGD90563.1 - 1.9e-32 110.9 8.5 3e-32 110.3 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGD90563.1 - 0.00014 21.7 5.1 0.00024 20.9 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGD90563.1 - 0.00016 21.5 3.7 0.00041 20.1 3.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGD90563.1 - 0.0014 18.4 4.1 0.0029 17.4 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGD90563.1 - 0.0019 18.5 6.2 0.0033 17.7 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 EGD90563.1 - 0.012 15.4 5.1 0.069 13.0 1.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGD90563.1 - 0.017 14.7 1.4 0.034 13.8 1.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EGD90563.1 - 0.03 14.3 7.2 0.23 11.4 7.7 2.0 1 1 1 2 2 2 0 zinc-RING finger domain DUF3797 PF12677.7 EGD90563.1 - 0.072 13.0 2.3 0.16 11.9 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_UBOX PF13445.6 EGD90563.1 - 0.39 10.8 6.8 0.78 9.8 6.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EGD90563.1 - 1.8 8.5 8.0 41 4.2 8.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF2582 PF10771.9 EGD90564.2 - 0.02 15.0 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) TMF_TATA_bd PF12325.8 EGD90564.2 - 0.021 15.0 0.4 0.15 12.3 0.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding adh_short PF00106.25 EGD90565.2 - 2.4e-24 85.9 0.0 3.4e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD90565.2 - 2.3e-14 53.6 0.0 3.2e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD90565.2 - 0.0029 17.6 0.1 0.0073 16.2 0.0 1.7 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 EGD90565.2 - 0.025 14.0 0.1 0.088 12.2 0.1 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EGD90565.2 - 0.11 12.4 0.1 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding DUF1263 PF06882.12 EGD90565.2 - 0.13 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1263) PEX11 PF05648.14 EGD90568.1 - 1.4e-33 116.3 0.1 1.7e-33 116.0 0.1 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FMN_red PF03358.15 EGD90569.1 - 9e-10 38.5 0.0 1.2e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGD90569.1 - 1.1e-07 31.8 0.0 1.3e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EGD90569.1 - 7.3e-05 23.0 0.2 0.0013 18.9 0.2 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EGD90569.1 - 0.0014 18.9 0.0 0.0051 17.0 0.0 1.8 1 1 1 2 2 2 1 Flavodoxin domain NPL4 PF05021.15 EGD90570.1 - 1.2e-139 465.0 0.0 1.5e-139 464.7 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EGD90570.1 - 9.5e-69 230.1 0.1 1.5e-68 229.5 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EGD90570.1 - 0.0052 17.2 0.0 0.025 15.1 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Kinesin PF00225.23 EGD90571.1 - 1.2e-116 389.3 0.1 2e-116 388.6 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGD90571.1 - 1.3e-26 93.4 1.4 2e-26 92.7 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Herpes_UL14 PF03580.14 EGD90571.1 - 0.0038 17.5 1.6 0.012 15.9 1.6 1.9 1 0 0 1 1 1 1 Herpesvirus UL14-like protein ArgoL2 PF16488.5 EGD90571.1 - 0.13 12.7 0.3 0.33 11.3 0.3 1.8 1 0 0 1 1 1 0 Argonaute linker 2 domain ING PF12998.7 EGD90571.1 - 1.8 9.2 7.4 2.9 8.5 2.4 3.2 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF5565 PF17720.1 EGD90572.2 - 0.15 10.9 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5565) Tim17 PF02466.19 EGD90573.1 - 0.00029 21.2 3.4 0.00039 20.8 2.7 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family cNMPbd_u2 PF16643.5 EGD90576.1 - 3.3e-38 131.6 9.0 3.3e-38 131.6 9.0 1.7 2 0 0 2 2 2 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 EGD90576.1 - 1.5e-29 101.9 0.0 1.1e-15 57.5 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 EGD90576.1 - 2.1e-10 39.8 8.4 1.4 9.2 0.0 8.3 10 0 0 10 10 10 4 Leucine Rich repeat F-box-like PF12937.7 EGD90576.1 - 3.2e-06 26.9 1.7 6.2e-06 26.0 0.5 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EGD90576.1 - 8.2e-06 26.1 8.2 0.04 14.3 0.1 6.5 5 2 3 8 8 8 3 Leucine Rich repeats (2 copies) F-box PF00646.33 EGD90576.1 - 3.7e-05 23.5 1.2 3.7e-05 23.5 1.2 3.4 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 EGD90576.1 - 0.0025 18.1 10.1 54 4.9 0.1 7.8 10 0 0 10 10 10 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 EGD90576.1 - 0.091 13.0 3.8 8.8 6.6 0.6 4.1 3 2 0 3 3 3 0 Ste50p, sterile alpha motif Zn_clus PF00172.18 EGD90577.2 - 0.0033 17.5 1.2 0.0079 16.3 1.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ZapB PF06005.12 EGD90577.2 - 0.005 17.2 0.0 0.0095 16.4 0.0 1.4 1 0 0 1 1 1 1 Cell division protein ZapB NRBF2 PF08961.10 EGD90577.2 - 0.0089 15.7 0.2 0.013 15.1 0.2 1.2 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 EGD90577.2 - 0.024 15.2 0.0 0.044 14.4 0.0 1.4 1 0 0 1 1 1 0 Initiation control protein YabA RasGAP_C PF03836.15 EGD90577.2 - 0.058 13.6 0.0 0.069 13.3 0.0 1.4 1 1 0 1 1 1 0 RasGAP C-terminus APC_N_CC PF16689.5 EGD90577.2 - 0.098 12.7 0.0 0.24 11.5 0.0 1.6 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain TSC22 PF01166.18 EGD90577.2 - 0.14 12.5 0.2 0.3 11.4 0.2 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family PikAIV_N PF18605.1 EGD90577.2 - 0.17 11.5 8.5 0.7 9.5 1.1 2.4 1 1 1 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain VEGFR-2_TMD PF17988.1 EGD90577.2 - 0.21 11.0 1.7 0.35 10.3 1.7 1.3 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Slx4 PF09494.10 EGD90578.1 - 4.2e-25 87.5 0.3 7.2e-25 86.7 0.3 1.4 1 0 0 1 1 1 1 Slx4 endonuclease CGI-121 PF08617.10 EGD90579.1 - 2.8e-59 199.9 0.5 3.2e-59 199.7 0.5 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 HTH_40 PF14493.6 EGD90579.1 - 0.069 13.6 0.1 0.31 11.5 0.1 2.0 1 1 2 3 3 3 0 Helix-turn-helix domain Bax1-I PF01027.20 EGD90580.1 - 6.6e-33 114.3 10.5 1.1e-32 113.5 10.5 1.4 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Cutinase PF01083.22 EGD90582.2 - 7.7e-25 87.9 0.0 9.7e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.16 EGD90582.2 - 0.00013 21.9 0.0 0.00013 21.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase LIP PF03583.14 EGD90582.2 - 0.018 14.4 0.0 0.031 13.6 0.0 1.4 1 1 1 2 2 2 0 Secretory lipase Abhydrolase_8 PF06259.12 EGD90582.2 - 0.05 13.2 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.20 EGD90582.2 - 0.061 13.0 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 EGD90582.2 - 0.067 12.7 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_6 PF12697.7 EGD90582.2 - 0.13 12.9 0.0 0.13 12.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family RRM_1 PF00076.22 EGD90583.1 - 1e-15 57.3 0.0 1.5e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGD90583.1 - 0.0072 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.7 EGD90583.1 - 0.93 10.1 13.8 15 6.3 10.6 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Glyco_hydro_76 PF03663.14 EGD90584.1 - 1e-24 87.7 0.2 9.8e-17 61.5 0.1 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 DUF2236 PF09995.9 EGD90585.1 - 1.4e-07 31.9 0.0 2.7e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2205 PF10224.9 EGD90590.1 - 5.6e-33 112.8 0.4 1e-32 111.9 0.4 1.4 1 0 0 1 1 1 1 Short coiled-coil protein Macoilin PF09726.9 EGD90590.1 - 0.011 14.4 3.7 0.013 14.1 3.7 1.0 1 0 0 1 1 1 0 Macoilin family YabA PF06156.13 EGD90590.1 - 0.017 15.7 0.3 0.029 15.0 0.3 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF4208 PF13907.6 EGD90590.1 - 0.021 15.2 0.1 0.033 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) DivIC PF04977.15 EGD90590.1 - 0.026 14.3 0.4 0.043 13.6 0.4 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4201 PF13870.6 EGD90590.1 - 0.027 14.2 0.4 0.038 13.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) CASP_C PF08172.12 EGD90590.1 - 0.039 13.3 0.8 0.039 13.3 0.8 2.0 2 0 0 2 2 2 0 CASP C terminal HALZ PF02183.18 EGD90590.1 - 0.043 14.0 2.8 0.097 12.9 0.2 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper PI3K_P85_iSH2 PF16454.5 EGD90590.1 - 0.047 13.3 0.2 0.061 12.9 0.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Prefoldin PF02996.17 EGD90590.1 - 0.072 13.0 0.6 0.11 12.4 0.6 1.4 1 0 0 1 1 1 0 Prefoldin subunit NAM-associated PF14303.6 EGD90590.1 - 8.6 7.1 10.4 20 5.9 10.3 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain 14-3-3 PF00244.20 EGD90592.1 - 9.8e-105 349.0 7.3 1.2e-104 348.7 7.3 1.1 1 0 0 1 1 1 1 14-3-3 protein IATP PF04568.12 EGD90593.1 - 6e-26 90.7 2.0 6.7e-26 90.6 2.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Pannexin_like PF12534.8 EGD90593.1 - 0.14 11.2 0.2 0.15 11.2 0.2 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Nsp1_C PF05064.13 EGD90594.1 - 6.7e-43 145.2 3.4 1.5e-42 144.1 3.4 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EGD90594.1 - 0.00036 21.3 31.0 0.00036 21.3 31.0 6.6 1 1 3 4 4 3 3 Nucleoporin FG repeat region ParB PF08775.10 EGD90594.1 - 0.037 14.5 0.4 0.037 14.5 0.4 1.9 2 1 0 2 2 2 0 ParB family HIP1_clath_bdg PF16515.5 EGD90594.1 - 0.16 12.6 14.1 1.5 9.4 6.0 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2935 PF11155.8 EGD90594.1 - 0.29 11.5 1.1 3.1 8.2 1.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) OmpH PF03938.14 EGD90594.1 - 0.43 10.9 12.3 2.3 8.6 0.1 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.6 EGD90594.1 - 0.57 10.6 12.1 0.22 11.9 6.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FlaC_arch PF05377.11 EGD90594.1 - 0.59 10.6 9.1 0.98 9.9 0.4 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 EGD90594.1 - 0.76 9.8 6.4 1.1 9.3 4.8 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 EGD90594.1 - 0.98 8.0 7.8 2 7.0 7.5 1.5 1 1 0 1 1 1 0 AAA domain DUF4407 PF14362.6 EGD90594.1 - 1 8.6 9.7 0.64 9.3 7.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) IFT57 PF10498.9 EGD90594.1 - 1.8 7.4 10.8 0.15 11.0 3.9 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 EGD90594.1 - 1.9 8.5 8.7 1.8 8.6 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EGD90594.1 - 2.7 8.0 10.3 4.3 7.3 3.0 2.3 1 1 0 2 2 2 0 Laminin Domain II FliT PF05400.13 EGD90594.1 - 2.9 8.8 6.2 1.2 10.0 0.9 2.6 1 1 1 2 2 2 0 Flagellar protein FliT CK2S PF15011.6 EGD90594.1 - 3.3 7.6 7.8 1.9 8.4 3.4 2.2 2 0 0 2 2 2 0 Casein Kinase 2 substrate Med21 PF11221.8 EGD90594.1 - 3.5 7.9 14.9 1.2e+02 2.9 14.9 3.0 1 1 0 1 1 1 0 Subunit 21 of Mediator complex CREPT PF16566.5 EGD90594.1 - 5 7.3 7.0 1.1 9.4 1.7 2.1 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour V-SNARE PF05008.15 EGD90594.1 - 5.1 7.5 9.5 1.2 9.6 0.7 3.1 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Occludin_ELL PF07303.13 EGD90594.1 - 5.5 7.8 5.0 7.4 7.4 1.9 2.2 2 0 0 2 2 2 0 Occludin homology domain ATG16 PF08614.11 EGD90594.1 - 6.6 6.9 16.1 0.58 10.4 6.8 2.8 1 1 1 2 2 1 0 Autophagy protein 16 (ATG16) GAT PF03127.14 EGD90594.1 - 8.9 6.7 7.1 13 6.2 0.2 2.8 1 1 1 2 2 2 0 GAT domain DUF5102 PF17104.5 EGD90595.1 - 1.9e-115 385.9 2.5 1.9e-115 385.9 2.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5102) DUF4543 PF15076.6 EGD90595.1 - 0.17 12.1 0.8 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) zf-MIZ PF02891.20 EGD90596.2 - 2e-10 40.3 0.2 4.3e-10 39.2 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger DUF281 PF03436.13 EGD90596.2 - 0.17 12.3 1.0 0.76 10.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF281) DUF3157 PF11355.8 EGD90596.2 - 3.2 7.3 9.1 22 4.6 4.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3157) PH PF00169.29 EGD90597.1 - 2.7e-10 40.7 0.3 5.4e-09 36.5 0.3 2.7 1 1 0 1 1 1 1 PH domain SH3_1 PF00018.28 EGD90597.1 - 5.6e-10 38.7 0.0 1.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGD90597.1 - 3e-09 36.6 0.1 7.2e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 EGD90597.1 - 5.6e-08 32.8 0.1 9.4e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 EGD90597.1 - 0.00011 21.9 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 EGD90597.1 - 0.00043 20.7 0.0 0.0015 18.9 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.30 EGD90597.1 - 0.0018 18.7 0.1 0.0034 17.8 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 EGD90597.1 - 0.034 14.4 0.0 0.095 13.0 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Ribosomal_L14 PF00238.19 EGD90599.2 - 5.7e-34 116.8 0.0 6.8e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 EGD90599.2 - 0.21 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Hist_deacetyl PF00850.19 EGD90600.2 - 1.8e-31 109.8 0.1 5.7e-31 108.1 0.0 1.8 2 0 0 2 2 2 1 Histone deacetylase domain Glycoprotein_G PF00802.19 EGD90600.2 - 0.41 10.0 5.0 0.64 9.3 5.0 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G JAB PF01398.21 EGD90601.1 - 1.1e-33 115.7 0.0 2.5e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGD90601.1 - 5.4e-12 46.1 0.7 8.7e-12 45.4 0.7 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EGD90601.1 - 6.2e-08 32.4 0.0 4.6e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain NIF PF03031.18 EGD90603.1 - 1.5e-40 138.5 0.0 2.1e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Fungal_trans PF04082.18 EGD90605.2 - 1.7e-16 60.1 0.0 5.4e-16 58.4 0.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD90605.2 - 2.4e-06 27.6 6.3 4.4e-06 26.7 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cas_Csy1 PF09611.10 EGD90605.2 - 0.12 11.4 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) F-box-like PF12937.7 EGD90606.1 - 9.2e-06 25.5 1.0 2.4e-05 24.1 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD90606.1 - 0.002 17.9 0.5 0.0042 16.9 0.5 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 EGD90606.1 - 0.034 15.0 0.1 1.2e+02 3.8 0.2 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat EspF PF04806.12 EGD90606.1 - 0.15 12.5 11.8 0.075 13.4 2.1 3.4 2 0 0 2 2 2 0 EspF protein repeat Pkinase PF00069.25 EGD90611.1 - 9.4e-73 244.8 0.0 1.6e-72 244.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90611.1 - 1.9e-38 132.2 0.0 4.8e-38 130.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD90611.1 - 0.00096 18.5 0.1 0.66 9.2 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EGD90611.1 - 0.037 13.9 1.3 1.8 8.4 0.0 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGD90611.1 - 0.27 9.9 0.0 0.27 9.9 0.0 2.4 3 1 1 4 4 4 0 Fungal protein kinase MFS_1 PF07690.16 EGD90612.1 - 1.9e-29 102.7 34.4 1.1e-20 73.9 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD90612.1 - 3.6e-22 78.8 15.0 5.1e-22 78.4 15.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGD90613.1 - 6.8e-27 94.3 41.1 6.8e-27 94.3 41.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD90613.1 - 2.2e-08 33.4 35.8 1.4e-05 24.2 13.2 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter M20_dimer PF07687.14 EGD90614.2 - 0.11 12.4 2.5 2.8 7.9 0.3 2.6 2 0 0 2 2 2 0 Peptidase dimerisation domain HAMP PF00672.25 EGD90615.2 - 1.9e-36 124.2 15.8 6.3e-08 32.9 0.5 7.8 6 2 2 8 8 8 5 HAMP domain HATPase_c PF02518.26 EGD90615.2 - 2.6e-33 114.9 0.0 1.4e-32 112.5 0.0 2.4 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGD90615.2 - 9.4e-25 87.0 1.2 5.7e-24 84.4 0.5 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EGD90615.2 - 6.9e-17 61.3 4.4 2.1e-16 59.7 0.1 4.0 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain DUF4279 PF14106.6 EGD90615.2 - 7.8e-06 26.1 0.0 3.4 7.9 0.0 5.5 5 1 0 5 5 5 1 Domain of unknown function (DUF4279) DUF3829 PF12889.7 EGD90615.2 - 0.00089 18.8 14.1 0.035 13.6 0.2 5.0 5 1 1 6 6 6 2 Protein of unknown function (DUF3829) DUF948 PF06103.11 EGD90615.2 - 0.0014 18.9 48.0 1.2 9.4 0.1 9.2 3 1 3 6 6 6 2 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 EGD90615.2 - 0.0017 18.7 15.6 5.6 7.4 0.0 6.9 3 2 3 6 6 6 1 Syntaxin-like protein Fib_alpha PF08702.10 EGD90615.2 - 0.014 15.6 34.0 2.6 8.2 0.1 7.3 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family NOD PF06816.13 EGD90615.2 - 0.043 13.4 0.0 5.8 6.6 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein AdHead_fibreRBD PF16812.5 EGD90615.2 - 0.044 13.6 0.4 0.044 13.6 0.4 3.3 3 1 1 4 4 4 0 C-terminal head domain of the fowl adenovirus type 1 long fibre IcmF_C PF06744.12 EGD90615.2 - 0.055 13.1 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal Vps52 PF04129.12 EGD90615.2 - 0.057 12.2 4.5 4.6 5.9 0.2 3.9 4 0 0 4 4 4 0 Vps52 / Sac2 family Gp-FAR-1 PF05823.12 EGD90615.2 - 0.076 13.4 4.2 40 4.6 0.0 4.7 1 1 3 6 6 6 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SpoIIID PF12116.8 EGD90615.2 - 0.083 13.0 2.7 24 5.1 0.1 4.5 4 0 0 4 4 4 0 Stage III sporulation protein D CMD PF02627.20 EGD90615.2 - 0.52 10.4 2.1 8.2 6.6 0.1 3.7 4 0 0 4 4 4 0 Carboxymuconolactone decarboxylase family WXG100 PF06013.12 EGD90615.2 - 0.91 9.8 20.9 13 6.1 0.3 7.1 6 3 1 7 7 7 0 Proteins of 100 residues with WXG DUF2877 PF11392.8 EGD90615.2 - 1 10.1 9.0 11 6.8 0.2 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2877) CENP-F_leu_zip PF10473.9 EGD90615.2 - 2.1 8.4 28.1 3.3 7.7 0.2 7.5 5 3 2 8 8 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GLE1 PF07817.13 EGD90615.2 - 3 7.0 11.3 19 4.4 0.4 4.4 3 1 2 5 5 5 0 GLE1-like protein GhoS PF11080.8 EGD90615.2 - 3 7.9 7.4 4.1 7.5 0.1 3.9 4 0 0 4 4 4 0 Endoribonuclease GhoS tRNA-synt_2d PF01409.20 EGD90618.1 - 2.3e-88 295.8 0.0 3.1e-88 295.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EGD90618.1 - 1.3e-16 60.6 0.5 1.3e-16 60.6 0.5 2.0 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA-synt_2 PF00152.20 EGD90618.1 - 5.7e-05 22.3 0.1 0.0033 16.6 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA_synthFbeta PF17759.1 EGD90618.1 - 6.9e-05 22.4 0.0 0.044 13.2 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 EGD90618.1 - 0.00054 19.9 0.5 0.0014 18.5 0.5 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 DUF2564 PF10819.8 EGD90618.1 - 0.031 14.6 0.1 0.076 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) LRRC37 PF15779.5 EGD90618.1 - 0.068 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Leucine-rich repeat-containing protein 37 family Ribosomal_S21e PF01249.18 EGD90619.1 - 5.3e-42 141.8 0.0 5.9e-42 141.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.28 EGD90620.1 - 3.5e-07 30.3 0.0 1.7e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.25 EGD90621.1 - 1.9e-130 434.9 4.7 2.3e-130 434.6 4.7 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EGD90621.1 - 1.3e-17 63.9 0.1 1.2e-08 35.3 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 EGD90621.1 - 8.1e-08 31.7 0.8 1.7e-07 30.6 0.8 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EGD90621.1 - 2e-06 27.4 7.6 0.0027 17.2 6.6 2.9 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 EGD90621.1 - 0.00011 21.7 2.5 0.00044 19.8 2.5 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein PK PF00224.21 EGD90621.1 - 0.0019 17.1 0.1 0.0046 15.9 0.0 1.7 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain Aldolase PF01081.19 EGD90621.1 - 0.0064 15.9 1.6 0.054 12.9 1.4 2.3 1 1 0 1 1 1 1 KDPG and KHG aldolase ThiG PF05690.14 EGD90621.1 - 0.031 13.6 0.5 0.031 13.6 0.5 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 EGD90621.1 - 0.078 12.1 3.5 0.14 11.3 3.5 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase YpsA PF06908.11 EGD90621.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family EAL PF00563.20 EGD90621.1 - 0.17 11.4 0.4 17 4.8 0.0 2.5 2 1 0 2 2 2 0 EAL domain G3P_antiterm PF04309.12 EGD90621.1 - 0.3 10.5 1.8 2.7 7.4 0.2 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator RasGAP PF00616.19 EGD90622.1 - 3.5e-52 177.1 0.0 7.8e-52 176.0 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGD90622.1 - 2.1e-50 170.4 4.7 7.7e-50 168.6 4.7 2.1 1 0 0 1 1 1 1 RasGAP C-terminus CH PF00307.31 EGD90622.1 - 2.6e-13 50.1 0.0 1.7e-12 47.5 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 EGD90622.1 - 6.9e-10 37.8 43.8 0.22 11.4 0.0 15.2 17 0 0 17 17 17 7 IQ calmodulin-binding motif CAMSAP_CH PF11971.8 EGD90622.1 - 0.017 14.9 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 0 CAMSAP CH domain Acylphosphatase PF00708.18 EGD90622.1 - 0.038 14.4 1.2 12 6.3 0.2 3.0 2 0 0 2 2 2 0 Acylphosphatase Trypan_PARP PF05887.11 EGD90622.1 - 0.044 13.8 4.1 0.098 12.6 4.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) IZUMO PF15005.6 EGD90622.1 - 0.084 13.4 0.1 0.38 11.3 0.1 2.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated ENTH PF01417.20 EGD90623.1 - 2.3e-46 156.9 0.1 4e-46 156.1 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EGD90623.1 - 0.001 18.2 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain SH3_1 PF00018.28 EGD90624.1 - 3.2e-11 42.6 0.0 5.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGD90624.1 - 7e-09 35.4 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGD90624.1 - 4.1e-07 29.6 0.0 7.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.16 EGD90625.2 - 8.2e-11 41.4 17.6 1e-10 41.1 17.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CVNH PF08881.10 EGD90629.1 - 1.3e-25 90.0 0.3 1.5e-25 89.8 0.3 1.0 1 0 0 1 1 1 1 CVNH domain Pro_isomerase PF00160.21 EGD90632.2 - 1.7e-41 142.1 0.1 2.2e-41 141.8 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNase_PH PF01138.21 EGD90633.1 - 5.5e-33 114.3 0.6 1.2e-32 113.2 0.3 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 SNF2_N PF00176.23 EGD90634.1 - 4e-53 180.4 0.0 6.6e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 EGD90634.1 - 1.9e-24 85.5 0.1 4.9e-24 84.2 0.1 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 EGD90634.1 - 2.9e-19 69.4 0.0 1.1e-18 67.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGD90634.1 - 1.9e-08 33.8 0.0 3.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EGD90634.1 - 3.8e-08 33.5 0.2 1.8e-07 31.3 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Ssu72 PF04722.13 EGD90635.1 - 4.1e-82 274.4 0.0 4.8e-82 274.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein PRIMA1 PF16101.5 EGD90635.1 - 0.19 11.8 8.6 0.33 11.0 8.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 EGD90635.1 - 3 7.9 4.4 4.1 7.4 4.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator VIR_N PF15912.5 EGD90635.1 - 3.9 7.0 5.9 5.7 6.5 5.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal zf-CHCC PF10276.9 EGD90636.1 - 0.01 15.8 4.0 0.17 12.0 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger domain zf-CCHC PF00098.23 EGD90636.1 - 0.053 13.6 3.3 0.1 12.7 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle PyrI_C PF02748.15 EGD90636.1 - 0.12 12.3 0.4 8.7 6.3 0.1 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 EGD90636.1 - 0.19 11.8 3.1 5.8 7.0 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger DUF3605 PF12239.8 EGD90639.1 - 2.2e-54 183.9 0.3 3.2e-54 183.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) EIAV_Rev PF11129.8 EGD90639.1 - 0.068 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus Isochorismatase PF00857.20 EGD90640.1 - 9.9e-26 91.0 0.0 9.4e-25 87.8 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family Hist_deacetyl PF00850.19 EGD90641.1 - 9.1e-78 261.8 0.0 1.3e-77 261.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.7 EGD90642.2 - 6.4e-14 52.4 3.7 1.1e-13 51.6 3.7 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGD90642.2 - 2.5e-05 24.1 9.7 4.6e-05 23.2 9.7 1.5 1 0 0 1 1 1 1 PHD-finger TFIIA PF03153.13 EGD90642.2 - 0.0029 17.7 7.5 0.004 17.2 7.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-HC5HC2H PF13771.6 EGD90642.2 - 0.037 14.3 0.4 0.079 13.2 0.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain SURF2 PF05477.11 EGD90642.2 - 0.49 10.1 5.2 0.78 9.4 5.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PHD_2 PF13831.6 EGD90642.2 - 0.51 9.9 3.8 1 9.0 3.8 1.5 1 0 0 1 1 1 0 PHD-finger Hamartin PF04388.12 EGD90642.2 - 1.7 7.3 12.4 2.3 6.8 12.4 1.1 1 0 0 1 1 1 0 Hamartin protein RNA_pol_Rpc34 PF05158.12 EGD90643.1 - 5.5e-105 351.5 0.0 6.6e-105 351.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TPR_1 PF00515.28 EGD90644.1 - 2.2e-38 128.5 23.9 2.2e-05 24.1 0.0 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 EGD90644.1 - 6.6e-37 125.2 6.4 6.9e-20 70.7 0.3 3.1 3 0 0 3 3 3 2 STI1 domain TPR_2 PF07719.17 EGD90644.1 - 1.3e-29 99.8 23.3 0.00026 20.9 0.1 10.0 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 EGD90644.1 - 1.7e-18 66.0 16.5 0.0042 16.7 0.0 7.9 6 1 2 8 8 8 5 TPR repeat TPR_19 PF14559.6 EGD90644.1 - 3.2e-15 56.4 20.8 0.00096 19.6 0.2 6.7 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGD90644.1 - 2.1e-14 52.5 21.8 0.01 16.0 0.1 8.9 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGD90644.1 - 1.2e-10 41.8 18.3 0.011 16.3 0.1 7.0 3 3 6 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 EGD90644.1 - 3.9e-10 39.7 3.9 0.0018 18.4 0.1 4.8 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGD90644.1 - 5.9e-09 36.0 21.0 1.1 10.2 0.3 9.4 8 2 2 10 10 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGD90644.1 - 6.2e-09 36.0 19.7 0.0002 21.5 0.3 6.3 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGD90644.1 - 2.5e-08 33.7 9.6 0.11 12.9 0.0 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGD90644.1 - 3.6e-07 29.7 12.2 0.0073 16.3 0.0 6.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGD90644.1 - 0.0004 20.1 11.0 0.31 10.9 0.1 6.5 6 1 1 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGD90644.1 - 0.0013 18.9 7.9 0.25 11.6 0.2 3.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGD90644.1 - 0.031 14.9 21.2 1.3 9.8 0.0 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat SPESP1 PF15754.5 EGD90644.1 - 0.057 12.6 0.6 0.16 11.2 0.6 1.7 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Inhibitor_I9 PF05922.16 EGD90644.1 - 0.09 13.5 0.0 0.42 11.3 0.0 2.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 SHNi-TPR PF10516.9 EGD90644.1 - 1.1 8.8 8.6 20 4.7 0.1 5.6 6 0 0 6 6 6 0 SHNi-TPR TetR_C_15 PF17918.1 EGD90644.1 - 1.8 9.3 4.8 7.7 7.3 3.9 2.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain C2 PF00168.30 EGD90645.1 - 4.1e-73 242.2 0.3 5.8e-19 68.3 0.0 5.4 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 EGD90645.1 - 0.012 15.1 0.0 0.063 12.7 0.0 2.1 1 1 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.9 EGD90645.1 - 0.14 11.9 0.1 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins APH PF01636.23 EGD90646.2 - 5.5e-12 46.1 0.0 8.3e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD90646.2 - 3.4e-05 23.6 0.0 8.1e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 EGD90646.2 - 0.0043 16.7 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family UDPGP PF01704.18 EGD90648.1 - 3.4e-189 628.7 0.0 4e-189 628.5 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.13 EGD90648.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Pilus assembly protein, PilO zf-CCCH PF00642.24 EGD90651.1 - 3.3e-08 33.2 20.0 3e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EGD90651.1 - 0.00044 20.0 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EGD90651.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 EGD90651.1 - 0.0087 16.7 3.1 0.5 11.1 0.2 2.5 2 0 0 2 2 2 2 Torus domain DUF4185 PF13810.6 EGD90652.2 - 0.0013 18.1 0.1 0.0018 17.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Amidase PF01425.21 EGD90653.1 - 1.2e-87 294.8 0.0 1.9e-87 294.1 0.0 1.3 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 EGD90654.1 - 3.6e-17 62.3 19.6 8e-17 61.2 19.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PhyH PF05721.13 EGD90655.1 - 1.9e-30 106.7 0.0 2.3e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HNH_2 PF13391.6 EGD90656.1 - 2.7e-13 49.8 0.1 4.9e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease Epimerase PF01370.21 EGD90657.1 - 3.9e-06 26.5 0.0 5.3e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 EGD90658.1 - 1.4e-05 25.1 11.8 2.4e-05 24.4 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGD90658.1 - 0.00065 18.8 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRP PF06011.12 EGD90660.1 - 1.8e-39 135.7 20.2 2.1e-37 128.9 20.2 2.2 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGD90660.1 - 8e-16 58.7 0.1 1.2e-15 58.0 0.1 1.3 1 0 0 1 1 1 1 ML-like domain Strabismus PF06638.11 EGD90660.1 - 3.3 6.2 5.5 5.4 5.6 5.5 1.2 1 0 0 1 1 1 0 Strabismus protein SUIM_assoc PF16619.5 EGD90661.2 - 4.6 7.4 25.9 1.3 9.1 3.3 3.3 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cys_Met_Meta_PP PF01053.20 EGD90662.1 - 1.3e-61 208.3 0.0 5.7e-61 206.2 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGD90662.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF2073 PF09846.9 EGD90662.1 - 0.011 15.7 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) Aminotran_1_2 PF00155.21 EGD90662.1 - 0.018 14.2 0.0 0.04 13.1 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II ThiS PF02597.20 EGD90663.1 - 0.00033 21.2 0.0 0.0032 18.1 0.0 1.9 1 1 0 1 1 1 1 ThiS family GFA PF04828.14 EGD90664.1 - 1.5e-23 82.9 1.6 1.5e-23 82.9 1.6 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme INPP5B_PH PF16776.5 EGD90664.1 - 0.098 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Zn_clus PF00172.18 EGD90665.1 - 2e-08 34.2 4.4 4e-08 33.3 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGD90665.1 - 2.8e-06 26.6 0.0 5.9e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_2 PF00152.20 EGD90667.2 - 1.4e-42 145.9 0.0 1.7e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Oxidored_q2 PF00420.24 EGD90670.2 - 0.041 13.5 2.4 0.064 12.9 0.0 2.4 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PUD PF03714.14 EGD90670.2 - 0.079 13.8 1.0 15 6.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial pullanase-associated domain PEP_mutase PF13714.6 EGD90671.1 - 6.9e-68 228.7 1.6 7.8e-68 228.5 1.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Aminotran_MocR PF12897.7 EGD90671.1 - 0.024 13.4 0.2 0.08 11.7 0.2 1.8 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase Pantoate_transf PF02548.15 EGD90671.1 - 0.086 12.2 0.1 2.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase Lectin_like PF18560.1 EGD90671.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Lectin like domain ABC_membrane PF00664.23 EGD90672.1 - 4.1e-07 29.9 0.1 2.3e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_23 PF13476.6 EGD90672.1 - 2e-05 25.2 0.0 3.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGD90672.1 - 0.00086 19.8 0.0 0.002 18.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EGD90672.1 - 0.0072 16.0 0.1 0.018 14.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 EGD90672.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EGD90672.1 - 0.12 12.7 0.0 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGD90672.1 - 0.12 12.2 0.3 0.39 10.6 0.3 1.8 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 EGD90672.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PhoD PF09423.10 EGD90673.1 - 9.7e-112 373.4 1.1 1.2e-111 373.2 1.1 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EGD90673.1 - 8.5e-35 119.2 0.1 2e-34 118.0 0.1 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EGD90673.1 - 5.7e-05 23.6 0.1 0.00017 22.1 0.1 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain LigD_N PF13298.6 EGD90674.1 - 2.9e-35 120.7 0.0 4.9e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Pheromone PF08015.11 EGD90674.1 - 6 8.0 5.9 1.2 10.2 1.1 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone Peptidase_M28 PF04389.17 EGD90676.2 - 7.2e-30 104.2 0.0 1.3e-29 103.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 Rhodanese PF00581.20 EGD90679.1 - 4.8e-07 30.3 0.0 7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain HTH_22 PF13309.6 EGD90679.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 HTH domain MutS_V PF00488.21 EGD90680.2 - 2.8e-67 226.4 0.2 5.7e-67 225.4 0.2 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGD90680.2 - 3.5e-41 141.5 0.1 7.5e-41 140.5 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EGD90680.2 - 2.3e-33 114.8 0.1 1.3e-32 112.4 0.1 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 EGD90680.2 - 4.4e-15 55.8 2.6 1.1e-14 54.5 2.6 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EGD90680.2 - 3.3e-12 46.8 0.0 1.3e-11 44.9 0.0 2.1 1 1 0 1 1 1 1 MutS domain II AAA_23 PF13476.6 EGD90680.2 - 0.0016 19.0 3.4 0.02 15.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EGD90680.2 - 0.015 14.9 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EGD90680.2 - 0.046 13.5 0.4 0.11 12.3 0.2 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGD90680.2 - 0.054 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain tRNA-synt_1b PF00579.25 EGD90681.2 - 5e-46 157.3 0.0 7.7e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EGD90681.2 - 5.1e-44 148.9 0.0 9.6e-44 148.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain Raffinose_syn PF05691.12 EGD90682.2 - 8.6e-55 185.9 2.6 2.9e-51 174.2 1.0 3.9 2 1 1 3 3 3 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 EGD90682.2 - 0.0028 16.7 0.0 0.0043 16.1 0.0 1.3 1 0 0 1 1 1 1 Melibiase SnAC PF14619.6 EGD90682.2 - 0.22 12.2 0.0 0.45 11.1 0.0 1.4 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex Aldedh PF00171.22 EGD90683.1 - 3.3e-165 550.1 0.3 3.7e-165 549.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRN9 PF10680.9 EGD90684.1 - 1.6e-22 79.6 1.0 3.5e-22 78.5 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor zf-C2H2 PF00096.26 EGD90684.1 - 0.14 12.7 0.1 0.32 11.5 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type PIG-U PF06728.13 EGD90686.1 - 8e-119 397.1 22.4 9.1e-119 396.9 22.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Acetyltransf_1 PF00583.25 EGD90687.1 - 6.1e-12 45.8 0.0 8.1e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGD90687.1 - 3.9e-09 36.8 0.0 6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGD90687.1 - 7.6e-09 35.6 0.0 1.6e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD90687.1 - 2.2e-05 24.3 0.0 4.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EGD90687.1 - 0.0011 19.1 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGD90687.1 - 0.036 14.7 0.0 0.051 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HIG_1_N PF04588.13 EGD90688.1 - 7.9e-30 102.9 0.6 1.1e-29 102.4 0.6 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PALP PF00291.25 EGD90689.1 - 5.5e-66 222.9 1.1 3.9e-65 220.2 1.1 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EGD90689.1 - 3.2e-41 139.0 0.0 1.7e-19 69.4 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.18 EGD90690.1 - 3.6e-21 75.1 9.8 7.2e-21 74.1 9.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L36 Med28 PF11594.8 EGD90690.1 - 0.036 14.1 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 28 GTP_EFTU PF00009.27 EGD90691.1 - 2.1e-58 197.1 0.4 3.9e-58 196.2 0.4 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGD90691.1 - 2.7e-33 114.3 0.0 5.9e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EGD90691.1 - 2.7e-32 110.7 0.0 5.6e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EGD90691.1 - 1.5e-24 85.8 0.0 3.8e-24 84.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGD90691.1 - 1.8e-11 44.3 0.0 4.6e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGD90691.1 - 1.6e-05 24.7 0.0 3.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain ATP_bind_1 PF03029.17 EGD90691.1 - 0.024 14.4 0.1 0.099 12.4 0.1 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Abhydrolase_6 PF12697.7 EGD90692.2 - 3.8e-12 47.3 0.2 5.7e-12 46.7 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGD90692.2 - 2.5e-08 33.5 0.0 5.1e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGD90692.2 - 1.4e-07 31.4 0.0 1.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EGD90692.2 - 0.00013 21.9 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.12 EGD90692.2 - 0.00047 19.2 0.0 0.00069 18.7 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 EGD90692.2 - 0.037 13.5 0.0 0.093 12.2 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family MAF_flag10 PF01973.18 EGD90692.2 - 0.092 12.4 0.0 0.35 10.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF115 TLD PF07534.16 EGD90694.2 - 1.1e-20 74.3 0.0 2.1e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 EGD90694.2 - 0.00018 22.4 0.2 0.00046 21.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function NMT_C PF02799.15 EGD90695.1 - 3.3e-90 301.2 0.2 4.9e-90 300.6 0.2 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EGD90695.1 - 2.1e-71 239.0 0.0 3.7e-71 238.1 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EGD90695.1 - 6.2e-05 23.1 0.0 0.00021 21.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain ATP-grasp_5 PF13549.6 EGD90695.1 - 0.18 11.2 0.0 7.3 6.0 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Mur_ligase_M PF08245.12 EGD90696.2 - 1.2e-06 28.6 1.0 5.5e-05 23.3 0.1 3.1 2 1 1 3 3 3 2 Mur ligase middle domain Syja_N PF02383.18 EGD90697.1 - 2.6e-86 289.8 0.0 3.3e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain FUN14 PF04930.15 EGD90697.1 - 0.028 14.8 0.1 1.2 9.5 0.0 3.0 3 0 0 3 3 3 0 FUN14 family zf-CCCH PF00642.24 EGD90698.1 - 3.2e-19 68.3 29.7 2.2e-06 27.4 0.7 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGD90698.1 - 1.5e-11 43.9 33.7 0.00058 19.8 2.5 5.2 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 EGD90698.1 - 1.3e-08 35.4 28.3 0.00022 21.9 1.0 5.4 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 EGD90698.1 - 4.1e-05 23.3 0.8 4.1e-05 23.3 0.8 5.0 5 0 0 5 5 5 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EGD90698.1 - 0.11 12.7 11.5 6.4 7.0 4.1 3.5 2 1 1 3 3 3 0 Zinc-finger containing family TRP_N PF14558.6 EGD90698.1 - 0.4 11.0 3.6 16 5.9 0.1 3.1 2 1 1 3 3 3 0 ML-like domain zf-C3H1 PF10650.9 EGD90698.1 - 3.2 7.6 11.2 1.2 9.0 0.4 3.5 3 0 0 3 3 3 0 Putative zinc-finger domain Glyco_hydro_18 PF00704.28 EGD90699.2 - 7.8e-71 239.3 0.0 9e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_75 PF07335.11 EGD90700.2 - 8.5e-48 162.7 1.0 1.3e-47 162.1 1.0 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF3712 PF12505.8 EGD90701.1 - 2.3e-33 115.1 3.5 3.6e-33 114.5 2.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF4307 PF14155.6 EGD90701.1 - 0.055 13.3 0.5 0.1 12.4 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Wzy_C PF04932.15 EGD90701.1 - 0.062 12.9 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 O-Antigen ligase Sel1 PF08238.12 EGD90702.1 - 4.7e-11 43.0 12.1 0.00031 21.3 2.6 4.1 4 0 0 4 4 4 3 Sel1 repeat Glyco_hydro_18 PF00704.28 EGD90703.1 - 7.4e-25 88.3 1.2 1.2e-23 84.3 1.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4849 PF16141.5 EGD90703.1 - 0.003 16.9 0.2 0.013 14.8 0.2 2.1 1 1 0 1 1 1 1 Putative glycoside hydrolase Family 18, chitinase_18 GDI PF00996.18 EGD90703.1 - 0.023 13.2 0.0 0.031 12.8 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Pkinase PF00069.25 EGD90706.2 - 9.4e-14 51.4 0.0 1.6e-12 47.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90706.2 - 5.2e-11 42.3 0.0 3.4e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Syndecan PF01034.20 EGD90708.1 - 0.32 11.0 1.2 0.77 9.7 1.2 1.6 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 EGD90708.1 - 0.55 11.1 2.4 2 9.4 2.3 2.1 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Yip1 PF04893.17 EGD90710.1 - 0.081 12.6 25.2 0.02 14.6 6.4 2.2 1 1 1 2 2 2 0 Yip1 domain 7tm_7 PF08395.12 EGD90710.1 - 3.2 6.9 14.7 4.5 6.4 13.9 1.6 1 1 0 1 1 1 0 7tm Chemosensory receptor DUF1776 PF08643.10 EGD90711.1 - 1e-86 291.0 0.0 1.2e-86 290.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 EGD90711.1 - 0.029 13.8 0.0 0.097 12.1 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase CHASE4 PF05228.13 EGD90711.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 CHASE4 domain zf-RanBP PF00641.18 EGD90712.2 - 1.4e-05 24.3 2.0 1.4e-05 24.3 2.0 3.1 2 1 0 3 3 3 2 Zn-finger in Ran binding protein and others LRS4 PF10422.9 EGD90712.2 - 0.091 12.3 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DZR PF12773.7 EGD90712.2 - 0.4 10.7 9.0 2 8.5 2.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 EGD90712.2 - 3 7.8 9.2 7.7 6.5 2.5 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Ribonuclease PF00545.20 EGD90716.1 - 2.2e-07 31.5 0.1 3.1e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 ribonuclease DIM PF08194.12 EGD90716.1 - 0.28 11.4 4.3 3 8.1 0.2 2.4 2 0 0 2 2 2 0 DIM protein WD40 PF00400.32 EGD90717.1 - 6.2e-46 153.4 34.0 2.3e-05 25.0 0.1 12.1 11 1 0 11 11 11 9 WD domain, G-beta repeat Utp12 PF04003.12 EGD90717.1 - 2.2e-22 79.4 0.1 5.6e-22 78.1 0.1 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EGD90717.1 - 2.6e-19 69.3 7.1 0.0035 17.6 0.0 9.6 6 2 3 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGD90717.1 - 1.4e-08 34.1 1.3 0.2 10.6 0.5 4.9 3 1 0 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGD90717.1 - 1.1e-05 25.0 0.0 0.3 10.4 0.1 3.8 3 1 1 4 4 4 2 WD40-like domain Nup160 PF11715.8 EGD90717.1 - 1.5e-05 23.8 1.2 0.53 8.9 0.0 4.7 5 1 0 5 5 5 2 Nucleoporin Nup120/160 Frtz PF11768.8 EGD90717.1 - 0.00097 17.6 0.1 0.089 11.1 0.0 2.4 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Utp13 PF08625.11 EGD90717.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain WD40_3 PF15911.5 EGD90717.1 - 0.12 12.3 0.0 2.4 8.2 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat P34-Arc PF04045.14 EGD90718.1 - 5.5e-104 347.1 0.0 6.5e-104 346.9 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 EGD90718.1 - 0.034 13.7 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) DUF2158 PF09926.9 EGD90718.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) DUF4294 PF14127.6 EGD90719.1 - 0.01 15.8 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) PP2C PF00481.21 EGD90721.1 - 3.3e-05 23.7 0.0 0.23 11.0 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EGD90721.1 - 0.01 15.8 0.1 0.027 14.4 0.1 1.8 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Lar_N PF09861.9 EGD90721.1 - 0.2 10.8 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Lactate racemase N-terminal domain Cmc1 PF08583.10 EGD90723.1 - 1.2e-18 66.8 7.0 1.5e-18 66.6 7.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like HECA PF15353.6 EGD90723.1 - 0.072 13.3 1.7 0.092 13.0 1.7 1.2 1 0 0 1 1 1 0 Headcase protein family homologue WD40 PF00400.32 EGD90724.1 - 3e-15 56.3 14.7 0.00037 21.2 0.6 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 EGD90724.1 - 0.00011 21.0 5.0 0.0032 16.2 1.1 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGD90724.1 - 0.0014 18.9 1.9 0.26 11.6 0.4 4.3 3 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGD90724.1 - 0.062 12.0 0.2 4.8 5.8 0.1 2.9 2 1 1 3 3 3 0 Nup133 N terminal like DUF4398 PF14346.6 EGD90724.1 - 0.24 12.0 8.6 0.61 10.8 8.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) RNA_polI_A34 PF08208.11 EGD90724.1 - 7.3 6.6 15.1 13 5.8 1.1 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Peptidase_S64 PF08192.11 EGD90728.2 - 1.5e-06 27.0 0.0 2.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 2 Peptidase family S64 RRN3 PF05327.11 EGD90729.1 - 1.1e-169 565.6 0.0 1.1e-169 565.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 tRNA-synt_2 PF00152.20 EGD90731.1 - 6.9e-70 235.6 0.0 1e-69 235.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EGD90731.1 - 1.1e-17 64.0 0.0 1.7e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EGD90731.1 - 9.1e-05 22.4 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGD90731.1 - 0.00087 18.8 0.0 0.99 8.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ank_2 PF12796.7 EGD90732.2 - 5.3e-30 103.8 0.1 7.5e-10 39.3 0.0 5.5 2 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGD90732.2 - 2.2e-20 70.6 0.3 0.0099 16.3 0.0 9.0 9 0 0 9 9 9 3 Ankyrin repeat Ank_4 PF13637.6 EGD90732.2 - 2.8e-18 66.0 2.9 0.0001 22.8 0.0 7.6 3 3 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EGD90732.2 - 4.1e-11 42.8 2.5 0.39 11.2 0.0 7.1 5 2 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EGD90732.2 - 3.7e-10 39.8 1.2 0.038 14.3 0.0 6.9 5 2 2 7 7 7 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EGD90732.2 - 0.052 13.5 0.0 35 4.4 0.0 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF3447) VWA_3_C PF18571.1 EGD90732.2 - 0.059 13.2 0.6 20 5.2 0.0 3.3 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain Sec15 PF04091.12 EGD90732.2 - 0.17 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like HLH PF00010.26 EGD90733.1 - 1.1e-13 50.9 0.3 2.8e-13 49.6 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Septin PF00735.18 EGD90735.2 - 1.6e-08 34.2 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Septin HSP90 PF00183.18 EGD90736.1 - 1.2e-220 733.8 29.6 1.5e-220 733.5 29.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGD90736.1 - 6.5e-15 55.6 0.1 1.2e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGD90736.1 - 3.1e-09 36.8 0.1 1e-08 35.1 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 EGD90736.1 - 0.071 13.1 0.2 0.26 11.3 0.2 1.9 1 0 0 1 1 1 0 Tumour suppressor protein NTF2 PF02136.20 EGD90737.1 - 3.7e-23 82.4 0.2 6e-23 81.7 0.2 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EGD90737.1 - 3e-08 33.4 0.1 5.3e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGD90737.1 - 0.031 14.3 0.0 0.08 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif PknG_rubred PF16919.5 EGD90738.1 - 0.41 10.8 2.5 7.6 6.7 2.5 2.0 1 1 0 1 1 1 0 Protein kinase G rubredoxin domain TPR_17 PF13431.6 EGD90740.1 - 6.1e-05 23.1 1.0 0.63 10.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGD90740.1 - 0.0021 17.7 4.8 0.19 11.5 0.0 3.9 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.28 EGD90740.1 - 0.0033 17.2 0.4 0.48 10.3 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGD90740.1 - 0.0086 16.1 0.3 0.72 10.1 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGD90740.1 - 0.055 13.8 4.7 2 8.8 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat UPF0560 PF10577.9 EGD90740.1 - 0.063 11.8 3.7 0.088 11.3 3.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TPR_14 PF13428.6 EGD90740.1 - 0.081 13.8 4.4 23 6.2 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGD90740.1 - 0.14 12.7 3.7 47 4.6 0.0 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat Nnf1 PF03980.14 EGD90741.1 - 9e-33 113.0 6.2 9e-33 113.0 6.2 1.8 1 1 1 2 2 2 1 Nnf1 SHE3 PF17078.5 EGD90741.1 - 0.0085 15.8 1.4 0.015 15.1 1.4 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF1887 PF09002.11 EGD90741.1 - 0.0094 14.7 0.7 0.012 14.4 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1887) DUF948 PF06103.11 EGD90741.1 - 0.014 15.7 0.8 0.037 14.3 0.5 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MCM_N PF14551.6 EGD90741.1 - 0.032 14.8 1.0 0.056 14.0 1.0 1.5 1 1 0 1 1 1 0 MCM N-terminal domain FlgN PF05130.12 EGD90741.1 - 0.049 14.1 8.2 0.053 14.0 5.9 2.0 1 1 0 2 2 2 0 FlgN protein DUF16 PF01519.16 EGD90741.1 - 0.059 13.9 4.0 0.087 13.3 4.0 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 Mod_r PF07200.13 EGD90741.1 - 0.068 13.3 7.3 0.075 13.1 5.5 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.21 EGD90741.1 - 0.13 12.3 7.8 0.18 11.9 3.3 2.5 2 0 0 2 2 2 0 bZIP transcription factor DUF1664 PF07889.12 EGD90741.1 - 0.21 11.6 4.2 0.31 11.1 3.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NYD-SP28 PF14772.6 EGD90741.1 - 0.22 11.6 8.1 0.12 12.4 4.9 2.1 2 0 0 2 2 2 0 Sperm tail Cnn_1N PF07989.11 EGD90741.1 - 0.24 11.6 4.5 0.11 12.7 1.1 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Nup54 PF13874.6 EGD90741.1 - 0.28 11.3 8.3 0.19 11.8 5.7 1.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Syntaxin-6_N PF09177.11 EGD90741.1 - 0.55 10.8 4.7 0.58 10.7 2.9 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TMPIT PF07851.13 EGD90741.1 - 0.96 8.6 2.7 1.4 8.1 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.11 EGD90741.1 - 1.5 9.3 5.6 0.74 10.3 1.7 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Fungal_TACC PF12709.7 EGD90741.1 - 2.1 8.8 6.5 0.73 10.3 1.9 2.5 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Pkinase PF00069.25 EGD90742.1 - 2e-75 253.6 0.0 2.8e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90742.1 - 4.3e-37 127.8 0.0 6.1e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGD90742.1 - 3.9e-05 22.8 0.0 0.00051 19.1 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGD90742.1 - 0.01 15.2 0.8 0.033 13.5 0.1 2.2 2 1 1 3 3 3 0 Kinase-like APH PF01636.23 EGD90742.1 - 0.05 13.5 0.1 0.05 13.5 0.1 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD90742.1 - 0.12 12.0 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EGD90742.1 - 0.34 10.2 4.8 0.059 12.7 0.7 1.8 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SIR2 PF02146.17 EGD90743.1 - 1.9e-29 102.8 0.0 3.2e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family AATase PF07247.12 EGD90744.1 - 3.9e-16 58.7 0.0 2.3e-13 49.6 0.0 2.5 2 1 0 2 2 2 2 Alcohol acetyltransferase Cation_efflux PF01545.21 EGD90745.1 - 5.5e-55 186.2 5.8 7.9e-55 185.7 5.8 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGD90745.1 - 0.00059 19.9 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter FGGY_C PF02782.16 EGD90746.1 - 2.4e-29 102.5 0.0 4.4e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGD90746.1 - 3.2e-18 66.2 0.0 4.7e-12 46.0 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Esterase PF00756.20 EGD90748.2 - 7.9e-47 160.0 0.0 9.5e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 EGD90748.2 - 0.00019 20.4 0.0 0.00036 19.5 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EGD90748.2 - 0.00032 20.3 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGD90748.2 - 0.0012 18.1 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EGD90748.2 - 0.0083 15.6 0.0 0.21 11.0 0.0 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase Tannase PF07519.11 EGD90748.2 - 0.02 13.8 0.1 0.03 13.2 0.1 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase Lipase_3 PF01764.25 EGD90748.2 - 0.021 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 EGD90748.2 - 0.026 14.3 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein AXE1 PF05448.12 EGD90748.2 - 0.052 12.2 0.0 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 EGD90748.2 - 0.063 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_C50 PF03568.17 EGD90749.1 - 1e-149 499.0 0.0 2.2e-149 497.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 EGD90749.1 - 0.0002 20.9 0.0 0.0014 18.1 0.0 2.3 1 1 1 2 2 2 1 CHAT domain TPR_2 PF07719.17 EGD90749.1 - 0.18 12.0 10.3 10 6.5 0.2 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 EGD90749.1 - 0.43 10.3 5.1 3.4 7.3 0.0 3.6 4 0 0 4 4 4 0 26S proteasome subunit RPN7 DUF5321 PF17254.2 EGD90750.1 - 1.5e-50 170.7 0.4 1.9e-50 170.5 0.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5321) DUF2852 PF11014.8 EGD90750.1 - 0.015 15.5 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Muted PF14942.6 EGD90750.1 - 0.02 15.2 1.9 0.027 14.8 1.9 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF1611 PF07755.11 EGD90750.1 - 0.044 13.1 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain KaiB PF07689.12 EGD90750.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 KaiB domain CREPT PF16566.5 EGD90750.1 - 0.075 13.2 0.8 0.11 12.7 0.8 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fungal_trans PF04082.18 EGD90755.2 - 1.5e-18 66.8 0.1 2.1e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ZipA_C PF04354.13 EGD90755.2 - 0.19 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain Pectate_lyase_3 PF12708.7 EGD90759.2 - 3.6e-87 291.7 10.9 2.9e-71 239.7 4.6 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGD90759.2 - 0.00035 20.2 0.2 0.00084 19.0 0.2 1.6 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase Zn_clus PF00172.18 EGD90762.1 - 2.8e-07 30.5 10.0 6.3e-07 29.4 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 EGD90765.2 - 2.6e-38 131.9 0.0 6e-35 120.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGD90765.2 - 2.7e-11 43.8 0.0 1.3e-08 35.3 0.0 3.0 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGD90765.2 - 0.0026 17.7 0.6 0.24 11.4 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding GAT PF03127.14 EGD90767.1 - 1.6e-20 73.2 0.2 4.1e-20 71.9 0.2 1.7 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 EGD90767.1 - 0.035 14.0 0.9 0.11 12.3 0.0 2.2 3 0 0 3 3 3 0 VHS domain API5 PF05918.11 EGD90767.1 - 0.14 10.9 0.3 0.88 8.3 0.1 2.0 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Ferric_reduct PF01794.19 EGD90768.1 - 2.9e-26 92.0 9.1 2.9e-26 92.0 9.1 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGD90768.1 - 6.9e-16 58.7 0.1 2e-13 50.7 0.0 2.7 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGD90768.1 - 5.4e-11 42.6 0.0 3.9e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 EGD90768.1 - 0.17 12.5 0.0 0.79 10.4 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Fungal_trans PF04082.18 EGD90770.1 - 1.2e-07 31.1 4.6 3.2e-07 29.7 0.0 3.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD90770.1 - 6.5e-06 26.2 11.1 1.2e-05 25.3 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Presenilin PF01080.17 EGD90770.1 - 0.19 10.4 3.3 0.33 9.7 3.3 1.3 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 EGD90770.1 - 1.2 7.4 10.9 1.9 6.8 10.9 1.2 1 0 0 1 1 1 0 Menin DUF4614 PF15391.6 EGD90770.1 - 1.2 9.1 10.3 20 5.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) adh_short PF00106.25 EGD90771.1 - 7.9e-44 149.5 0.3 1e-43 149.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD90771.1 - 1.1e-43 149.5 0.3 1.2e-43 149.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD90771.1 - 1.1e-09 38.5 0.3 1.5e-09 38.0 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGD90771.1 - 0.00044 19.8 0.1 0.0033 16.9 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGD90771.1 - 0.0019 18.2 0.1 0.0051 16.7 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGD90771.1 - 0.0047 16.4 0.0 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 EGD90771.1 - 0.0069 15.8 0.0 0.0094 15.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.19 EGD90774.1 - 5.4e-56 188.8 0.0 7.3e-56 188.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGD90774.1 - 2.1e-18 66.3 0.0 2.5e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGD90774.1 - 0.0029 17.8 0.1 0.0071 16.5 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EGD90774.1 - 0.024 14.7 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ribosomal_L22 PF00237.19 EGD90775.2 - 2.8e-40 136.7 0.1 3.7e-40 136.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LSM PF01423.22 EGD90778.1 - 2.7e-20 71.8 1.0 3.5e-20 71.5 1.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGD90778.1 - 0.025 14.7 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 EGD90778.1 - 0.03 14.5 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Pan3_PK PF18101.1 EGD90779.2 - 1.6e-62 209.6 0.4 2.5e-62 208.9 0.4 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EGD90779.2 - 8.7e-06 25.3 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90779.2 - 0.12 11.6 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase UBA_4 PF14555.6 EGD90780.1 - 1.2e-11 44.2 0.0 2.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EGD90780.1 - 1.6e-08 34.6 0.0 3.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain Atg14 PF10186.9 EGD90780.1 - 0.036 13.2 4.9 0.056 12.5 4.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RR_TM4-6 PF06459.12 EGD90780.1 - 0.13 12.0 5.2 0.22 11.3 5.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAR2 PF05282.11 EGD90780.1 - 0.23 10.8 5.3 0.35 10.2 5.3 1.2 1 0 0 1 1 1 0 AAR2 protein DUF1682 PF07946.14 EGD90780.1 - 0.3 10.3 10.6 0.48 9.6 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ALMT PF11744.8 EGD90780.1 - 7.1 5.3 4.9 10 4.8 4.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 EGD90780.1 - 7.6 5.2 8.4 11 4.6 8.4 1.1 1 0 0 1 1 1 0 Presenilin PALP PF00291.25 EGD90781.1 - 3e-59 200.9 0.2 5.2e-59 200.1 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 EGD90781.1 - 2e-23 83.2 0.1 8.2e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGD90781.1 - 2.3e-19 69.3 0.0 7.5e-19 67.7 0.0 1.9 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGD90781.1 - 0.00021 21.1 0.1 0.00045 20.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 EGD90781.1 - 0.0073 15.4 0.0 8.8 5.2 0.0 3.1 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Vps39_2 PF10367.9 EGD90782.2 - 5.6e-08 33.2 0.0 1.3e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CASP_C PF08172.12 EGD90783.1 - 1.9e-90 302.6 0.4 1.9e-90 302.6 0.4 3.4 3 1 0 3 3 3 1 CASP C terminal HTH_Crp_2 PF13545.6 EGD90783.1 - 0.049 13.6 1.2 0.16 11.9 1.2 2.0 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF3455 PF11937.8 EGD90784.1 - 4.4e-42 144.2 0.0 5.4e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 EGD90784.1 - 0.00038 20.6 0.0 0.00073 19.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) Fibrillarin PF01269.17 EGD90785.2 - 1.2e-97 325.5 0.0 1.6e-97 325.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EGD90785.2 - 5.7e-06 26.2 0.0 9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 EGD90785.2 - 0.025 14.2 0.0 0.055 13.1 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EGD90785.2 - 0.04 13.7 0.1 0.066 13.0 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Epimerase PF01370.21 EGD90786.1 - 6.1e-20 71.7 0.0 7.8e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGD90786.1 - 1.9e-12 47.3 0.0 4.5e-12 46.0 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGD90786.1 - 3.4e-10 39.4 0.0 4.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGD90786.1 - 0.00024 20.4 0.0 0.32 10.1 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EGD90786.1 - 0.00027 20.9 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EGD90786.1 - 0.00051 19.2 0.0 0.00092 18.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EGD90786.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EGD90786.1 - 0.0016 17.9 0.0 0.0058 16.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Ldh_1_N PF00056.23 EGD90786.1 - 0.023 14.8 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Nitroreductase PF00881.24 EGD90787.1 - 3.8e-16 59.6 0.0 4.8e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Phosphoesterase PF04185.14 EGD90787.1 - 0.081 12.1 0.1 0.18 11.0 0.0 1.5 1 1 1 2 2 2 0 Phosphoesterase family MFS_1 PF07690.16 EGD90788.1 - 1.1e-32 113.4 62.0 1.2e-31 110.0 45.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M16 PF00675.20 EGD90789.1 - 8.6e-55 184.8 0.0 3.1e-54 183.0 0.1 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGD90789.1 - 1.2e-39 136.2 0.0 2.6e-38 131.9 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain ADH_zinc_N PF00107.26 EGD90790.1 - 9.2e-22 77.4 0.0 1.3e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGD90790.1 - 2e-18 66.3 0.0 3.7e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EGD90790.1 - 1.1e-11 45.9 0.0 1.8e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 EGD90790.1 - 0.27 11.0 0.0 0.79 9.4 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2855) CybS PF05328.12 EGD90791.1 - 1.7e-50 170.2 0.0 2.1e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Maf PF02545.14 EGD90792.1 - 1.2e-45 155.4 0.0 1.4e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein HNH_2 PF13391.6 EGD90793.1 - 6.6e-15 55.0 0.0 1.4e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease HLH PF00010.26 EGD90794.1 - 3.9e-09 36.3 0.1 1e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Hamartin PF04388.12 EGD90794.1 - 0.0079 14.9 2.2 0.0092 14.7 2.2 1.0 1 0 0 1 1 1 1 Hamartin protein GFA PF04828.14 EGD90795.1 - 0.054 13.8 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme FoP_duplication PF13865.6 EGD90796.2 - 5.6 7.6 8.9 0.73 10.4 0.2 3.2 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 Ribonuc_L-PSP PF01042.21 EGD90797.2 - 4.9e-39 133.1 0.0 5.6e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DEAD PF00270.29 EGD90798.2 - 2.4e-24 86.0 0.4 1.4e-23 83.6 0.4 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD90798.2 - 4.9e-23 81.6 0.0 1.2e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD90798.2 - 0.00013 22.0 0.0 0.00028 20.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EGD90798.2 - 0.051 12.3 0.0 0.92 8.2 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 T4SS-DNA_transf PF02534.14 EGD90798.2 - 0.15 10.8 0.1 0.46 9.2 0.0 1.8 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Alpha-amylase PF00128.24 EGD90799.2 - 3e-24 86.2 0.4 1.5e-23 83.9 0.4 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EGD90799.2 - 3.2e-05 22.3 1.1 0.0083 14.4 0.0 2.5 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 But2 PF09792.9 EGD90801.1 - 0.073 13.5 0.0 0.29 11.5 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain Ank_2 PF12796.7 EGD90805.1 - 4.1e-30 104.2 0.2 7.9e-10 39.2 0.0 4.6 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD90805.1 - 1.2e-19 70.3 1.2 0.00015 22.2 0.0 6.1 3 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD90805.1 - 2e-18 64.5 2.6 0.016 15.7 0.0 7.6 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 EGD90805.1 - 1.4e-16 60.1 4.9 0.00063 20.1 0.1 7.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EGD90805.1 - 7.1e-15 54.9 1.7 1.4e-06 28.5 0.0 4.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Helo_like_N PF17111.5 EGD90805.1 - 0.00021 20.7 2.2 0.0005 19.5 2.2 1.7 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_2 PF12796.7 EGD90806.2 - 1.2e-16 61.0 0.1 1.9e-05 25.2 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD90806.2 - 1.5e-13 50.9 0.3 0.00059 20.4 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD90806.2 - 4.6e-09 35.8 0.2 0.045 14.3 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EGD90806.2 - 1.3e-06 28.6 0.4 0.0027 18.0 0.0 4.1 1 1 3 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EGD90806.2 - 2.8e-06 27.5 0.9 0.064 13.7 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat SPX PF03105.19 EGD90806.2 - 2e-05 24.7 0.0 4.5e-05 23.5 0.1 1.5 2 0 0 2 2 2 1 SPX domain ATPgrasp_N PF18130.1 EGD90808.1 - 5.7e-16 58.9 0.0 1.6e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EGD90808.1 - 6.1e-08 32.4 0.0 3.1e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGD90808.1 - 6.7e-07 29.0 0.0 1.3e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EGD90808.1 - 0.00055 20.0 0.0 0.07 13.2 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EGD90808.1 - 0.063 13.0 0.0 0.41 10.4 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon tRNA-synt_1c PF00749.21 EGD90811.1 - 1.2e-97 326.6 0.0 1.7e-97 326.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGD90811.1 - 1.2e-29 103.4 0.0 3.4e-29 102.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF3408 PF11888.8 EGD90811.1 - 6.5 6.9 7.5 14 5.8 7.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) MFS_1 PF07690.16 EGD90813.1 - 1.2e-29 103.4 59.0 8.8e-28 97.2 57.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD90813.1 - 2.1e-07 30.2 12.7 2.1e-07 30.2 12.7 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter SpoVS PF04232.12 EGD90813.1 - 5.6 6.8 9.6 4.7 7.0 1.8 2.7 2 1 1 3 3 3 0 Stage V sporulation protein S (SpoVS) HSP70 PF00012.20 EGD90814.1 - 4.6e-62 210.0 18.0 2.3e-61 207.8 2.5 3.1 3 1 0 3 3 3 2 Hsp70 protein DUF4296 PF14129.6 EGD90814.1 - 0.042 14.5 0.5 0.39 11.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) Myb_DNA-bind_3 PF12776.7 EGD90814.1 - 1.2 10.2 6.0 1.3 10.0 0.1 3.4 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain Tubulin_3 PF14881.6 EGD90817.2 - 1.4e-81 272.5 0.1 2.9e-81 271.5 0.1 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EGD90817.2 - 6.7e-42 142.5 0.6 1.6e-41 141.4 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EGD90817.2 - 1.3e-05 25.5 0.0 0.028 14.6 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain DinB_2 PF12867.7 EGD90818.1 - 0.31 11.6 2.7 3.2 8.3 0.0 2.6 2 0 0 2 2 2 0 DinB superfamily TTKRSYEDQ PF10212.9 EGD90818.1 - 0.35 9.8 9.0 1.3 7.9 4.3 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 EGD90818.1 - 0.65 8.8 19.7 1.3 7.8 19.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_23 PF13476.6 EGD90818.1 - 2.7 8.5 10.5 6.8 7.1 10.5 1.8 1 0 0 1 1 1 0 AAA domain Luteo_P1-P2 PF08467.10 EGD90818.1 - 3.6 6.7 11.0 48 3.1 9.9 2.5 2 1 0 2 2 2 0 Luteovirus RNA polymerase P1-P2/replicase Exonuc_VII_L PF02601.15 EGD90818.1 - 3.9 7.0 11.2 8.2 5.9 11.2 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 EGD90818.1 - 9 6.3 24.2 0.68 10.0 9.6 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF2347 PF09804.9 EGD90819.1 - 1.3e-101 339.9 0.0 2.5e-101 339.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EGD90819.1 - 2.6e-61 207.3 0.7 3.8e-61 206.8 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 EGD90819.1 - 9.4e-07 27.9 0.0 0.0031 16.3 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.10 EGD90819.1 - 0.038 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis Barttin PF15462.6 EGD90819.1 - 0.13 12.0 0.7 0.3 10.8 0.7 1.5 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) EBP PF05241.12 EGD90820.2 - 3.5e-56 189.5 9.8 4.5e-56 189.1 9.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein SNF2_N PF00176.23 EGD90821.1 - 1.9e-64 217.6 0.0 2.8e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGD90821.1 - 7.2e-15 55.3 0.0 1.6e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD90821.1 - 5.1e-10 39.6 0.0 1.5e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGD90821.1 - 0.015 14.5 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 START PF01852.19 EGD90825.2 - 0.09 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 START domain Urease_linker PF18473.1 EGD90825.2 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Urease subunit beta-alpha linker domain Sulfotransfer_3 PF13469.6 EGD90826.2 - 0.0054 17.1 0.1 2.7 8.3 0.1 2.8 1 1 0 2 2 2 2 Sulfotransferase family KAAG1 PF15354.6 EGD90826.2 - 0.018 15.6 2.6 0.028 15.0 1.2 2.1 2 1 1 3 3 3 0 Kidney-associated antigen 1 ATG27 PF09451.10 EGD90827.2 - 9.3e-84 281.4 0.0 1.1e-83 281.1 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EGD90827.2 - 0.00031 20.8 0.1 0.22 11.6 0.1 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF1242 PF06842.12 EGD90827.2 - 0.024 14.4 0.1 0.16 11.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) SRP9-21 PF05486.12 EGD90827.2 - 0.3 11.5 1.7 0.55 10.7 1.7 1.3 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Prefoldin_2 PF01920.20 EGD90828.1 - 1.2e-22 79.8 3.9 1.6e-22 79.4 3.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Osmo_CC PF08946.10 EGD90828.1 - 0.036 14.3 2.6 0.098 12.9 2.6 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil GPS2_interact PF15784.5 EGD90828.1 - 0.041 14.3 0.4 0.041 14.3 0.4 2.2 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain LPP PF04728.13 EGD90828.1 - 0.1 13.0 2.3 0.11 13.0 0.1 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF3338 PF11819.8 EGD90828.1 - 0.11 12.5 7.5 1.7 8.6 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) Mei5 PF10376.9 EGD90828.1 - 0.18 11.7 7.8 0.23 11.3 7.8 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein RGCC PF15151.6 EGD90828.1 - 0.26 11.5 4.3 0.12 12.7 1.7 1.7 2 0 0 2 2 2 0 Response gene to complement 32 protein family Syntaxin-6_N PF09177.11 EGD90828.1 - 0.27 11.8 5.6 3.3 8.3 5.5 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CENP-F_leu_zip PF10473.9 EGD90828.1 - 0.29 11.2 14.6 0.3 11.1 0.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EGD90828.1 - 0.5 10.4 3.0 1.9 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 EGD90828.1 - 0.61 10.3 11.0 0.71 10.1 0.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 EGD90828.1 - 0.65 9.3 11.6 4.7 6.5 6.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 EGD90828.1 - 1.4 9.4 19.2 0.87 10.1 1.8 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region bZIP_1 PF00170.21 EGD90828.1 - 1.6 8.9 12.4 0.11 12.6 2.4 2.2 2 0 0 2 2 2 0 bZIP transcription factor Spc7 PF08317.11 EGD90828.1 - 1.8 7.4 12.1 0.92 8.3 0.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-H PF05837.12 EGD90828.1 - 2.3 8.7 10.9 1.4 9.4 0.6 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.15 EGD90828.1 - 6.1 6.7 12.1 2.8 7.8 0.6 2.3 2 0 0 2 2 2 0 Septum formation initiator N2227 PF07942.12 EGD90831.2 - 1.8e-86 289.7 0.0 3.3e-86 288.8 0.0 1.4 1 1 0 1 1 1 1 N2227-like protein HSP70 PF00012.20 EGD90832.1 - 3.4e-10 38.8 0.1 8.2e-09 34.2 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EGD90832.1 - 0.14 11.0 0.0 0.38 9.5 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein DUF3445 PF11927.8 EGD90834.2 - 2.6e-59 200.6 0.1 3.8e-59 200.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Lipase_GDSL_3 PF14606.6 EGD90834.2 - 0.023 14.9 0.0 0.065 13.4 0.0 1.7 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family 4HBT_3 PF13622.6 EGD90835.1 - 1.3e-78 264.7 1.0 1.6e-78 264.4 1.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EGD90835.1 - 4.1e-25 88.1 0.0 1.2e-11 44.6 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Pkinase PF00069.25 EGD90836.2 - 6.8e-20 71.5 0.0 3.4e-19 69.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90836.2 - 0.00044 19.6 0.0 0.0046 16.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGD90836.2 - 0.059 13.3 0.1 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGD90836.2 - 0.14 11.4 0.1 65 2.7 0.0 3.0 2 1 1 3 3 3 0 Kinase-like 5_nucleotid_C PF02872.18 EGD90837.2 - 0.0058 16.9 0.0 0.016 15.4 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Pkinase PF00069.25 EGD90838.1 - 1.5e-16 60.6 0.0 2.4e-09 37.0 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90838.1 - 6.5e-06 25.6 0.1 0.016 14.5 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 EGD90838.1 - 0.066 12.6 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Smim3 PF17307.2 EGD90839.2 - 0.056 12.9 1.3 0.1 12.1 1.3 1.4 1 0 0 1 1 1 0 Small integral membrane protein 3 Methyltransf_23 PF13489.6 EGD90840.2 - 6.5e-19 68.4 0.0 1.2e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD90840.2 - 8.4e-13 48.8 0.0 2.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD90840.2 - 6e-08 33.3 0.0 3.8e-07 30.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD90840.2 - 8.8e-08 32.7 0.0 2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD90840.2 - 3.8e-07 30.0 0.0 2.9e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGD90840.2 - 0.00061 19.4 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EGD90840.2 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 EGD90840.2 - 0.0067 15.8 0.0 0.2 11.0 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EGD90840.2 - 0.012 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 EGD90840.2 - 0.018 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EGD90840.2 - 0.03 14.4 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EGD90840.2 - 0.084 12.3 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Ribosomal_S7 PF00177.21 EGD90841.1 - 4.2e-37 127.1 1.7 5.2e-37 126.8 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.12 EGD90842.2 - 5.4e-89 299.0 57.7 1e-88 298.1 49.7 2.9 2 1 0 2 2 2 2 SDA1 RNR_inhib PF08591.10 EGD90843.1 - 7.9e-25 88.3 0.7 1.7e-24 87.1 0.1 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Carb_anhydrase PF00194.21 EGD90844.1 - 6.1e-33 114.4 0.0 1.3e-32 113.4 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase AMP-binding PF00501.28 EGD90845.2 - 1.3e-65 221.7 0.1 1.3e-36 126.2 0.0 4.5 2 2 0 2 2 2 2 AMP-binding enzyme HMGL-like PF00682.19 EGD90846.1 - 1.6e-80 270.5 0.0 2.5e-80 269.8 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EGD90846.1 - 6.5e-21 74.6 0.0 1.2e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DEAD PF00270.29 EGD90847.1 - 4.5e-46 156.8 0.0 8.9e-46 155.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD90847.1 - 1.3e-29 102.8 0.3 1.4e-27 96.2 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EGD90847.1 - 0.0092 14.8 2.2 0.021 13.6 0.2 2.5 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Arf PF00025.21 EGD90849.2 - 4.9e-47 159.6 0.0 5.4e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGD90849.2 - 6.7e-08 32.1 0.4 2e-07 30.5 0.4 1.6 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 EGD90849.2 - 8.7e-07 28.7 0.0 1e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD90849.2 - 1.1e-05 25.6 0.0 1.5e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGD90849.2 - 7.6e-05 22.2 0.0 8.3e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGD90849.2 - 0.00077 19.0 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HCV_NS1 PF01560.17 EGD90849.2 - 0.028 13.1 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 DUF4045 PF13254.6 EGD90850.1 - 4.1e-93 313.3 48.8 4.1e-93 313.3 48.8 6.0 3 3 2 5 5 5 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 EGD90850.1 - 8.7e-11 41.6 0.0 0.0041 17.0 0.0 3.8 3 0 0 3 3 3 3 Gelsolin repeat ALO PF04030.14 EGD90851.1 - 6.5e-91 304.7 0.1 1e-90 304.1 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EGD90851.1 - 2e-31 108.6 0.1 3.2e-31 107.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 EGD90853.1 - 3.5e-17 62.5 0.0 1.4e-15 57.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGD90853.1 - 7.4e-09 35.5 0.0 1.9e-07 30.9 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD90853.1 - 1.3e-07 31.7 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 EGD90854.2 - 1.1e-09 37.7 0.4 1.7e-09 37.1 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PDEase_II PF02112.15 EGD90855.2 - 7.2e-56 189.7 0.0 7.4e-27 94.4 0.0 3.0 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 EGD90855.2 - 0.00094 18.8 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGD90855.2 - 0.0023 17.9 0.1 0.0051 16.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SPRY PF00622.28 EGD90856.1 - 1.2e-19 70.6 0.0 1.2e-19 70.6 0.0 1.8 2 0 0 2 2 2 1 SPRY domain TFIIA PF03153.13 EGD90856.1 - 0.00059 19.9 9.4 0.00059 19.9 9.4 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EGD90856.1 - 0.021 15.5 1.7 0.021 15.5 1.7 3.6 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Band_3_cyto PF07565.13 EGD90856.1 - 1.1 9.0 6.3 2.1 8.1 6.3 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spt20 PF12090.8 EGD90856.1 - 4.4 6.8 22.5 0.14 11.8 9.9 2.2 2 0 0 2 2 2 0 Spt20 family GREB1 PF15782.5 EGD90856.1 - 9.4 3.2 7.7 16 2.4 7.7 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3984 PF13136.6 EGD90857.1 - 0.047 13.1 8.5 0.074 12.5 8.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3984) Peptidase_S64 PF08192.11 EGD90858.2 - 1.7e-06 26.8 0.0 3.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.6 EGD90858.2 - 0.038 14.9 0.0 0.13 13.2 0.0 1.9 1 1 0 1 1 1 0 Trypsin-like peptidase domain Trypsin PF00089.26 EGD90858.2 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Trypsin Peptidase_M24 PF00557.24 EGD90859.1 - 5.5e-53 179.8 0.0 7.2e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGD90859.1 - 1.4e-22 79.7 0.0 2.8e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain NAD_binding_8 PF13450.6 EGD90859.1 - 0.17 12.1 0.1 9.8 6.5 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DnaJ PF00226.31 EGD90861.2 - 2.7e-16 59.4 0.6 6.7e-16 58.2 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 EGD90861.2 - 6.7e-14 51.7 0.0 6.4e-13 48.5 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain Amidase PF01425.21 EGD90862.2 - 1.3e-74 251.8 0.3 5.1e-74 249.9 0.3 1.7 1 1 0 1 1 1 1 Amidase GWT1 PF06423.12 EGD90863.1 - 1.8e-39 135.2 4.3 5.5e-39 133.7 2.4 2.5 2 0 0 2 2 2 1 GWT1 DUF4818 PF16089.5 EGD90863.1 - 0.012 16.1 2.9 0.17 12.3 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4818) OAR PF03826.17 EGD90864.1 - 1.3 8.9 6.2 1.5 8.8 0.3 2.5 2 0 0 2 2 2 0 OAR domain Acyl-CoA_dh_1 PF00441.24 EGD90868.2 - 4.7e-38 130.8 6.2 7.1e-38 130.2 6.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGD90868.2 - 5.9e-29 101.0 0.7 1.9e-28 99.4 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGD90868.2 - 2.3e-24 85.4 0.0 7.3e-24 83.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGD90868.2 - 2.7e-14 53.6 2.4 3.9e-14 53.1 2.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AgrD PF05931.11 EGD90868.2 - 0.0051 16.8 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 Staphylococcal AgrD protein HpaB_N PF11794.8 EGD90868.2 - 0.013 15.2 0.0 0.037 13.7 0.0 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Stanniocalcin PF03298.13 EGD90869.1 - 1.7e-05 24.3 0.0 1.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Stanniocalcin family tRNA-synt_1f PF01921.18 EGD90869.1 - 0.16 10.9 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) Senescence PF06911.12 EGD90870.1 - 5e-55 186.7 1.3 7.9e-55 186.0 1.3 1.3 1 0 0 1 1 1 1 Senescence-associated protein RCR PF12273.8 EGD90870.1 - 2.9 8.6 10.5 3 8.5 6.8 2.6 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Pkinase PF00069.25 EGD90872.1 - 1.5e-63 214.7 0.0 2.3e-63 214.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD90872.1 - 1.1e-34 120.0 0.0 2.6e-29 102.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGD90872.1 - 2.7e-06 26.9 0.0 0.00061 19.2 0.0 2.2 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGD90872.1 - 0.0006 19.8 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGD90872.1 - 0.0034 17.0 0.0 0.0081 15.8 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EGD90872.1 - 0.016 14.1 0.2 0.027 13.4 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EGD90872.1 - 0.034 13.5 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MMM1 PF10296.9 EGD90877.1 - 2.1e-07 30.3 0.0 4.7e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Bap31 PF05529.12 EGD90878.2 - 1.8e-48 163.8 6.8 2.3e-48 163.5 6.8 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EGD90878.2 - 7.3e-16 57.9 3.8 1.1e-15 57.3 3.8 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 EGD90878.2 - 0.014 15.1 1.0 0.079 12.7 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.9 EGD90878.2 - 0.031 13.4 1.3 0.039 13.0 1.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 EGD90878.2 - 0.032 14.4 0.5 0.058 13.6 0.4 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cep57_MT_bd PF06657.13 EGD90878.2 - 0.075 13.5 0.1 0.15 12.6 0.1 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF4349 PF14257.6 EGD90878.2 - 0.12 11.8 0.2 0.12 11.8 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) zf-C2H2_aberr PF17017.5 EGD90880.2 - 0.00011 22.4 1.0 0.042 14.0 0.0 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-H2C2_2 PF13465.6 EGD90880.2 - 0.027 14.9 0.5 0.027 14.9 0.5 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGD90880.2 - 0.031 15.1 0.6 0.031 15.1 0.6 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGD90880.2 - 0.051 14.1 0.8 0.051 14.1 0.8 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF4719 PF15843.5 EGD90880.2 - 0.11 12.6 0.0 0.11 12.6 0.0 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4719) Macoilin PF09726.9 EGD90880.2 - 4.1 5.8 7.9 7 5.1 7.9 1.3 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 EGD90881.2 - 3.1e-87 294.3 23.9 3.7e-87 294.0 23.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 EGD90881.2 - 0.0023 18.0 10.6 0.0023 18.0 10.6 3.5 2 2 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF2563 PF10817.8 EGD90881.2 - 0.28 11.8 2.5 0.42 11.3 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2563) DUF3391 PF11871.8 EGD90881.2 - 0.47 11.0 8.0 0.083 13.4 1.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Peptidase_S64 PF08192.11 EGD90883.1 - 0.00044 18.9 0.0 0.00069 18.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S64 ANAPC4_WD40 PF12894.7 EGD90884.1 - 8.1e-16 58.1 2.6 9.8e-06 25.8 0.1 4.3 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGD90884.1 - 1.8e-15 57.0 15.5 0.00048 20.9 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGD90884.1 - 1.6e-05 24.0 0.0 0.00093 18.2 0.0 3.0 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGD90884.1 - 0.00042 20.2 0.2 0.027 14.4 0.1 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A APH PF01636.23 EGD90885.1 - 0.00011 22.3 0.2 0.0016 18.4 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD90885.1 - 0.00011 21.9 0.2 0.00014 21.5 0.2 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kelch_4 PF13418.6 EGD90886.1 - 2.3e-27 94.7 5.8 9.2e-07 28.8 0.0 4.8 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGD90886.1 - 5.2e-25 87.0 0.2 1.1e-05 25.3 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 EGD90886.1 - 4.7e-23 80.2 1.4 4.2e-07 29.7 0.1 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 EGD90886.1 - 9e-23 79.7 3.5 9.4e-06 25.7 0.0 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EGD90886.1 - 3.6e-21 74.5 1.9 6.9e-06 25.5 0.1 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 EGD90886.1 - 7.8e-21 73.9 13.3 1.7e-07 31.3 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain BTB PF00651.31 EGD90886.1 - 5.3e-08 33.1 0.0 9.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Dus PF01207.17 EGD90887.2 - 1.5e-42 145.8 0.0 6.5e-30 104.3 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 EGD90887.2 - 0.00031 20.6 2.7 0.025 14.5 0.3 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGD90887.2 - 0.0018 18.3 7.2 0.067 13.3 1.8 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EGD90887.2 - 0.0046 16.7 1.0 0.0046 16.7 1.0 3.4 4 0 0 4 4 4 1 CCCH-type zinc finger Sel1 PF08238.12 EGD90890.2 - 2.9e-32 110.4 56.6 3.2e-06 27.6 1.5 13.1 15 1 1 16 16 16 8 Sel1 repeat TPR_16 PF13432.6 EGD90890.2 - 0.072 13.8 16.0 5.1 7.8 2.3 5.5 6 1 1 7 7 7 0 Tetratricopeptide repeat Pkinase PF00069.25 EGD90891.2 - 7.1e-06 25.6 0.0 8.5e-06 25.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Aldedh PF00171.22 EGD90892.1 - 1.6e-144 481.9 0.2 1.8e-144 481.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGD90892.1 - 0.12 11.8 0.1 0.26 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) DUF155 PF02582.14 EGD90893.1 - 5.7e-53 179.6 0.0 1.2e-52 178.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Serglycin PF04360.12 EGD90893.1 - 0.075 13.0 0.9 0.14 12.1 0.9 1.4 1 0 0 1 1 1 0 Serglycin Plasmodium_Vir PF05795.11 EGD90893.1 - 0.28 10.6 1.1 1.4 8.3 0.1 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein CDC45 PF02724.14 EGD90893.1 - 4.1 5.6 26.0 0.24 9.7 5.0 2.1 2 0 0 2 2 2 0 CDC45-like protein APH PF01636.23 EGD90894.2 - 2.9e-10 40.5 0.1 5.4e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Prophage_tail PF06605.11 EGD90894.2 - 0.18 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Prophage endopeptidase tail Occludin_ELL PF07303.13 EGD90896.2 - 0.002 18.8 1.2 0.0022 18.7 1.2 1.1 1 0 0 1 1 1 1 Occludin homology domain ELL PF10390.9 EGD90897.1 - 0.00014 21.5 0.0 0.00014 21.5 0.0 2.0 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL WD40 PF00400.32 EGD90899.1 - 1.7e-16 60.3 8.0 0.00029 21.6 0.1 5.5 6 1 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EGD90899.1 - 0.0001 21.2 0.1 0.15 10.8 0.0 2.2 2 0 0 2 2 2 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 EGD90899.1 - 0.00027 21.2 0.0 2.3 8.6 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PTH2 PF01981.16 EGD90901.1 - 4.5e-43 146.2 0.1 5.9e-43 145.9 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 HMGL-like PF00682.19 EGD90903.1 - 9.7e-79 264.6 0.3 1.4e-78 264.1 0.3 1.2 1 0 0 1 1 1 1 HMGL-like Hpt PF01627.23 EGD90907.1 - 3.1e-12 46.6 0.0 4.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Hpt domain DUF4448 PF14610.6 EGD90908.2 - 4.3e-37 127.7 0.0 5.5e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) LapA_dom PF06305.11 EGD90908.2 - 0.0026 17.5 0.5 0.0057 16.4 0.5 1.5 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain RhlB PF12300.8 EGD90909.2 - 0.12 12.5 0.4 0.15 12.2 0.4 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Pkinase PF00069.25 EGD90910.1 - 3.4e-13 49.6 0.0 4e-12 46.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain dsrm PF00035.26 EGD90911.1 - 0.00015 22.4 0.0 0.00025 21.7 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EGD90911.1 - 0.013 15.7 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF4692 PF15763.5 EGD90911.1 - 0.17 12.3 0.3 0.29 11.6 0.3 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Prenyltrans PF00432.21 EGD90912.1 - 4.2e-15 55.2 31.9 1e-12 47.6 1.1 5.3 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Zn_clus PF00172.18 EGD90913.1 - 0.0047 17.0 7.8 0.01 16.0 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ubiquitin PF00240.23 EGD90914.1 - 1.4e-101 332.3 14.2 2.3e-33 113.7 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 EGD90914.1 - 7.7e-48 160.2 14.9 1.8e-15 56.5 0.8 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGD90914.1 - 1.2e-17 64.1 6.8 0.00026 21.4 0.2 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 EGD90914.1 - 4.1e-12 45.9 2.5 0.018 15.0 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGD90914.1 - 1.1e-11 45.0 2.8 0.023 15.1 0.1 3.1 1 1 2 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGD90914.1 - 6.2e-11 42.4 1.6 0.078 13.1 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGD90914.1 - 4.1e-10 40.2 0.5 0.17 12.5 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGD90914.1 - 1.8e-07 31.2 0.3 0.71 9.7 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EGD90914.1 - 4.1e-06 26.8 16.7 11 6.1 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 EGD90914.1 - 5.9e-05 23.2 1.2 6.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 EGD90914.1 - 0.00024 21.4 0.0 20 5.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 EGD90914.1 - 0.00033 20.1 0.2 0.83 8.9 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 EGD90914.1 - 0.00036 21.2 0.1 22 5.9 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain ACT_5 PF13710.6 EGD90914.1 - 0.0012 18.6 2.3 13 5.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain Big_3_3 PF13750.6 EGD90914.1 - 0.0019 17.8 0.0 21 4.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) NEAT PF05031.12 EGD90914.1 - 0.0037 17.9 1.7 0.27 11.9 1.8 2.4 1 1 0 1 1 1 1 Iron Transport-associated domain DUF969 PF06149.12 EGD90914.1 - 0.0046 16.4 0.0 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) UDP-g_GGTase PF06427.11 EGD90914.1 - 0.0088 16.2 3.5 4.1 7.6 0.1 3.2 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase YcgR_2 PF12945.7 EGD90914.1 - 0.014 15.6 3.0 31 4.8 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR ACT_4 PF13291.6 EGD90914.1 - 0.019 15.6 0.3 79 3.9 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF493 PF04359.14 EGD90914.1 - 0.023 15.3 0.0 86 3.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 EGD90914.1 - 0.032 13.9 0.1 72 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ORF11CD3 PF10549.9 EGD90914.1 - 0.061 13.5 0.0 62 3.8 0.0 3.7 3 0 0 3 3 3 0 ORF11CD3 domain Tash_PEST PF07708.11 EGD90914.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif ProRS-C_2 PF09181.10 EGD90914.1 - 0.15 12.2 2.6 78 3.5 0.1 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Myosin_N PF02736.19 EGD90914.1 - 0.23 11.3 3.4 76 3.3 0.0 4.4 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 EGD90914.1 - 0.27 10.9 1.5 72 3.1 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif FlgD_ig PF13860.6 EGD90914.1 - 0.46 10.4 5.1 62 3.6 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain Phage_sheath_1N PF17481.2 EGD90914.1 - 0.56 10.7 5.3 2.5e+02 2.2 5.3 3.1 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain Plexin_cytopl PF08337.12 EGD90914.1 - 2.3 6.8 11.7 13 4.3 0.5 3.9 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 EGD90914.1 - 5.1 6.9 6.0 98 2.8 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain DivIC PF04977.15 EGD90915.1 - 0.0094 15.7 6.0 0.015 15.1 0.6 2.2 1 1 1 2 2 2 1 Septum formation initiator Vac_Fusion PF02346.16 EGD90915.1 - 0.016 14.9 1.3 0.048 13.3 0.3 2.0 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 BLOC1_2 PF10046.9 EGD90915.1 - 0.048 14.0 5.9 1.2 9.5 5.9 2.2 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.8 EGD90915.1 - 0.087 13.1 11.0 1.3 9.3 11.0 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding THOC7 PF05615.13 EGD90915.1 - 0.1 12.9 12.4 1.2 9.4 4.4 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 FapA PF03961.13 EGD90915.1 - 0.36 9.4 4.7 0.41 9.2 4.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4988 PF16378.5 EGD90915.1 - 0.4 10.3 2.0 1.1 8.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function Osmo_CC PF08946.10 EGD90915.1 - 0.53 10.6 8.8 1.6 9.1 1.8 2.8 1 1 2 3 3 3 0 Osmosensory transporter coiled coil DUF4349 PF14257.6 EGD90915.1 - 0.53 9.7 9.9 0.14 11.6 4.0 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4349) DUF4140 PF13600.6 EGD90915.1 - 0.74 10.3 7.7 6.6 7.2 7.7 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) LppA PF16708.5 EGD90915.1 - 1.2 9.0 4.2 1.1 9.1 0.8 1.9 1 1 1 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium MerR-DNA-bind PF09278.11 EGD90915.1 - 1.5 9.5 10.3 0.29 11.7 2.0 2.2 2 0 0 2 2 2 0 MerR, DNA binding AAA_23 PF13476.6 EGD90915.1 - 1.7 9.1 4.6 2.7 8.5 4.6 1.4 1 1 0 1 1 1 0 AAA domain bZIP_2 PF07716.15 EGD90915.1 - 2.3 8.4 10.9 1.7 8.8 0.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper ABC_tran_CTD PF16326.5 EGD90915.1 - 4.4 7.6 12.0 2.3e+02 2.1 11.1 2.5 1 1 0 1 1 1 0 ABC transporter C-terminal domain APG6_N PF17675.1 EGD90915.1 - 4.5 7.8 14.3 14 6.2 4.6 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region TPD52 PF04201.15 EGD90915.1 - 7.8 6.1 8.8 7.3 6.2 3.2 2.1 1 1 1 2 2 2 0 Tumour protein D52 family APH PF01636.23 EGD90916.1 - 4e-16 59.7 0.0 1e-15 58.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGD90916.1 - 0.0087 15.4 0.0 0.048 13.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 EGD90916.1 - 0.075 12.6 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-UBP PF02148.19 EGD90917.2 - 2.8e-20 72.4 4.4 7.1e-20 71.1 3.9 2.0 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EGD90917.2 - 7e-09 35.9 9.2 7e-09 35.9 9.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGD90917.2 - 1.1e-06 28.4 8.7 1.1e-06 28.4 8.7 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGD90917.2 - 0.00025 20.7 5.2 0.00025 20.7 5.2 2.7 2 1 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGD90917.2 - 0.00027 20.7 7.7 0.00027 20.7 7.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGD90917.2 - 0.00034 20.4 5.4 0.00034 20.4 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGD90917.2 - 0.00035 20.5 7.2 0.00035 20.5 7.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGD90917.2 - 0.00037 20.7 6.4 0.00037 20.7 6.4 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGD90917.2 - 0.00054 19.9 5.4 0.00054 19.9 5.4 2.7 2 1 0 2 2 1 1 RING-type zinc-finger JAKMIP_CC3 PF16034.5 EGD90917.2 - 0.00069 19.6 7.4 0.0011 18.9 7.4 1.3 1 0 0 1 1 1 1 JAKMIP CC3 domain Lectin_N PF03954.14 EGD90917.2 - 0.0017 18.1 2.5 0.002 17.9 1.0 1.8 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain zf-ANAPC11 PF12861.7 EGD90917.2 - 0.003 17.6 4.9 0.008 16.2 4.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger MIP-T3_C PF17749.1 EGD90917.2 - 0.0069 16.4 6.6 0.011 15.7 6.6 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region Prok-RING_4 PF14447.6 EGD90917.2 - 0.0082 16.0 5.0 0.0082 16.0 5.0 3.3 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 ERM PF00769.19 EGD90917.2 - 0.0092 15.8 15.5 0.011 15.5 15.5 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family zf-RING_6 PF14835.6 EGD90917.2 - 0.014 15.2 5.1 0.014 15.2 5.1 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein ATG16 PF08614.11 EGD90917.2 - 0.018 15.3 12.8 0.028 14.6 12.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 EGD90917.2 - 0.034 14.6 0.5 0.034 14.6 0.5 2.5 1 1 1 2 2 2 0 Cell division protein ZapB Taxilin PF09728.9 EGD90917.2 - 0.035 13.3 11.0 0.048 12.9 11.0 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein TolA_bind_tri PF16331.5 EGD90917.2 - 0.047 13.8 7.2 0.5 10.5 0.9 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation HALZ PF02183.18 EGD90917.2 - 0.055 13.7 1.7 2.1 8.7 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 EGD90917.2 - 0.11 12.6 18.6 0.2 11.7 18.6 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1993 PF09351.10 EGD90917.2 - 0.15 12.2 4.4 1.1 9.4 4.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) TLE_N PF03920.15 EGD90917.2 - 0.18 11.9 5.4 0.76 9.9 2.6 2.5 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain DUF4788 PF16032.5 EGD90917.2 - 0.19 10.7 2.3 0.23 10.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4788) GIT_CC PF16559.5 EGD90917.2 - 0.23 11.4 4.7 0.6 10.0 0.8 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Exonuc_VII_L PF02601.15 EGD90917.2 - 0.73 9.3 7.2 1 8.9 7.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YdjO PF14169.6 EGD90917.2 - 0.74 9.6 5.2 6.8 6.5 0.0 2.9 3 0 0 3 3 2 0 Cold-inducible protein YdjO UPF0242 PF06785.11 EGD90917.2 - 1 9.4 9.2 1.7 8.7 9.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TerY_C PF15616.6 EGD90917.2 - 1 9.5 13.0 1.1 9.3 1.3 2.4 1 1 1 2 2 2 0 TerY-C metal binding domain DUF3450 PF11932.8 EGD90917.2 - 1.5 8.1 14.7 3.1 7.0 11.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SHE3 PF17078.5 EGD90917.2 - 1.7 8.3 10.7 14 5.4 10.3 2.3 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF1664 PF07889.12 EGD90917.2 - 1.8 8.6 5.9 6.7 6.8 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 EGD90917.2 - 1.8 7.7 4.0 3 7.0 4.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein PRKG1_interact PF15898.5 EGD90917.2 - 1.9 9.4 13.5 0.93 10.4 10.6 1.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Zn_ribbon_17 PF17120.5 EGD90917.2 - 5.5 6.7 15.3 0.13 11.9 5.3 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type V_ATPase_I PF01496.19 EGD90917.2 - 6.4 4.5 6.9 8.8 4.1 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 EGD90917.2 - 7.3 5.0 7.0 9.5 4.6 7.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family BST2 PF16716.5 EGD90917.2 - 7.5 7.2 11.1 5.2 7.7 2.1 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 E1-E2_ATPase PF00122.20 EGD90920.1 - 1.9e-36 125.3 14.8 1.5e-29 102.8 0.5 3.3 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGD90920.1 - 3.5e-28 98.5 3.9 3.5e-28 98.5 3.9 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGD90920.1 - 2.8e-24 85.0 0.0 7.1e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGD90920.1 - 1.2e-18 68.1 1.0 1.9e-17 64.3 1.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGD90920.1 - 1.7e-14 53.3 0.1 4.1e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGD90920.1 - 3.2e-05 23.8 0.7 0.0021 17.8 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.6 EGD90923.1 - 1.2e-19 70.7 0.0 1.9e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD90923.1 - 1.5e-13 51.2 0.0 2.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD90923.1 - 2.3e-12 47.5 0.0 3.9e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD90923.1 - 9.3e-12 45.5 0.0 1.6e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD90923.1 - 2.6e-09 37.0 0.0 4.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EGD90923.1 - 0.11 12.0 0.0 2.8 7.4 0.0 2.1 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_24 PF13578.6 EGD90923.1 - 0.11 13.5 0.0 0.21 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 EGD90923.1 - 0.18 11.4 0.0 6.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.17 EGD90923.1 - 0.18 10.9 0.0 0.62 9.2 0.0 1.7 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Prp18 PF02840.15 EGD90923.1 - 0.27 11.3 0.2 0.57 10.2 0.2 1.5 1 0 0 1 1 1 0 Prp18 domain Dscam_C PF12355.8 EGD90923.1 - 0.4 11.7 7.6 0.8 10.7 7.6 1.5 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Caskin-Pro-rich PF16907.5 EGD90923.1 - 0.78 10.3 7.8 1.4 9.5 7.8 1.4 1 0 0 1 1 1 0 Proline rich region of Caskin proteins PRIMA1 PF16101.5 EGD90923.1 - 0.86 9.7 4.6 1.7 8.7 4.6 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EGD90923.1 - 2 7.8 7.0 3.1 7.2 7.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RCDG1 PF15725.5 EGD90923.1 - 3.2 8.3 11.1 7.9 7.0 11.1 1.6 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein zf-H2C2_2 PF13465.6 EGD90924.2 - 6.7e-17 61.1 28.0 2e-06 28.0 3.2 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 EGD90924.2 - 8.4e-17 60.6 30.5 0.0004 20.7 1.8 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGD90924.2 - 2.3e-09 37.3 28.1 0.026 15.4 3.2 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGD90924.2 - 4.5e-05 23.6 4.9 0.34 11.3 0.1 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EGD90924.2 - 0.0011 19.5 6.3 0.13 13.0 0.6 3.4 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 EGD90924.2 - 0.0046 17.1 0.8 2.1 8.4 0.1 2.3 2 1 0 2 2 2 2 Aberrant zinc-finger zf_UBZ PF18439.1 EGD90924.2 - 0.18 11.5 5.1 0.53 9.9 0.2 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 EGD90924.2 - 0.23 11.9 0.2 0.23 11.9 0.2 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EGD90924.2 - 0.24 11.2 15.1 0.055 13.2 2.1 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF4764 PF15961.5 EGD90924.2 - 0.32 9.6 6.2 0.14 10.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) Aminotran_1_2 PF00155.21 EGD90926.1 - 2.8e-92 309.7 0.0 3.2e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 EGD90927.1 - 3.6e-13 49.0 0.0 7.3e-13 48.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 EGD90927.1 - 9.9e-07 28.4 0.0 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EGD90927.1 - 1.7e-06 27.2 0.0 3.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGD90927.1 - 0.006 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_L30 PF00327.20 EGD90928.1 - 3.6e-12 46.0 0.2 5e-12 45.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Sec6 PF06046.13 EGD90929.1 - 3.8e-174 580.3 3.3 5.1e-174 579.8 3.3 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 AKAP7_NLS PF10469.9 EGD90930.1 - 2e-15 57.3 0.0 3.5e-15 56.4 0.0 1.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Frataxin_Cyay PF01491.16 EGD90931.1 - 1.1e-33 115.6 0.0 1.5e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain DUF1192 PF06698.11 EGD90931.1 - 0.097 12.7 0.5 0.2 11.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Rsbr_N PF08678.10 EGD90931.1 - 0.16 12.1 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 Rsbr N terminal zf-CSL PF05207.13 EGD90932.1 - 1.9e-21 75.6 0.1 2.3e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 CSL zinc finger Bromodomain PF00439.25 EGD90933.1 - 1.2e-38 131.0 1.0 1.5e-19 69.8 0.5 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EGD90933.1 - 3.7e-18 65.5 0.2 8.8e-18 64.2 0.2 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF3573 PF12097.8 EGD90933.1 - 0.22 10.3 2.4 0.48 9.2 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Utp12 PF04003.12 EGD90934.2 - 2.6e-22 79.2 0.3 6.6e-22 77.8 0.3 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family Mpp10 PF04006.12 EGD90934.2 - 6.7 5.0 34.5 1.9 6.8 0.3 2.2 2 0 0 2 2 2 0 Mpp10 protein WD40 PF00400.32 EGD90935.1 - 2.8e-10 40.6 2.6 6.2e-06 26.9 0.0 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD90935.1 - 2.8e-08 33.9 0.2 0.00019 21.7 0.1 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain QueH PF02677.14 EGD90935.1 - 0.19 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH APH PF01636.23 EGD90936.1 - 9e-16 58.5 0.1 1.3e-15 58.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD90936.1 - 2.2e-05 24.1 0.0 4.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EGD90936.1 - 0.0029 17.0 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF1679 PF07914.11 EGD90936.1 - 0.0035 16.3 0.2 0.48 9.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 EGD90936.1 - 0.033 13.4 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Pkinase_Tyr PF07714.17 EGD90936.1 - 0.17 11.1 0.1 1.2 8.3 0.1 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Glyco_hydro_56 PF01630.18 EGD90936.1 - 0.23 10.5 1.2 10 5.0 0.0 2.6 1 1 2 3 3 3 0 Hyaluronidase PPTA PF01239.22 EGD90939.2 - 1.3e-28 97.8 2.0 3.2e-08 33.0 0.1 3.5 3 1 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat RabGAP-TBC PF00566.18 EGD90940.2 - 8.9e-51 172.6 0.3 8.9e-51 172.6 0.3 2.9 2 2 0 2 2 2 1 Rab-GTPase-TBC domain Acetone_carb_G PF08882.11 EGD90940.2 - 0.31 11.2 1.5 2.2 8.5 0.1 2.3 2 0 0 2 2 2 0 Acetone carboxylase gamma subunit Glyoxalase_5 PF14696.6 EGD90941.2 - 0.0016 18.6 0.1 0.0065 16.6 0.0 1.9 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 EGD90941.2 - 0.032 14.4 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain Pectinesterase PF01095.19 EGD90941.2 - 0.048 12.4 0.0 0.067 11.9 0.0 1.3 1 0 0 1 1 1 0 Pectinesterase DUF3813 PF12758.7 EGD90941.2 - 1.7 9.0 4.1 0.64 10.4 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Ctf8 PF09696.10 EGD90942.1 - 1.8e-48 164.5 0.2 2.1e-48 164.3 0.2 1.0 1 0 0 1 1 1 1 Ctf8 Cnl2_NKP2 PF09447.10 EGD90944.1 - 3.5e-28 97.5 3.7 6.1e-28 96.8 3.7 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Syntaxin_2 PF14523.6 EGD90944.1 - 0.037 14.4 2.2 0.094 13.1 0.0 2.1 1 1 0 2 2 2 0 Syntaxin-like protein Mod_r PF07200.13 EGD90944.1 - 0.043 13.9 2.7 0.11 12.5 2.7 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 EGD90944.1 - 0.082 13.6 0.6 5.9 7.6 0.2 2.2 2 0 0 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 EGD90944.1 - 0.099 13.2 2.9 0.58 10.7 2.1 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region MRG PF05712.13 EGD90945.2 - 5e-60 202.2 0.0 6.3e-60 201.9 0.0 1.0 1 0 0 1 1 1 1 MRG DUF1741 PF08427.10 EGD90946.1 - 3.8e-84 282.0 0.5 7e-84 281.1 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) MFS_1 PF07690.16 EGD90947.2 - 6.3e-38 130.6 49.2 6.3e-38 130.6 49.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD90947.2 - 1e-12 47.7 12.1 1e-12 47.7 12.1 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter 2OG-Fe_Oxy_2 PF10014.9 EGD90948.1 - 2.8e-54 183.9 0.1 3.3e-54 183.6 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase V-SNARE PF05008.15 EGD90951.2 - 4.6e-23 81.4 7.2 4.6e-23 81.4 7.2 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EGD90951.2 - 3e-15 56.3 2.0 3e-15 56.3 2.0 2.9 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus DUF1542 PF07564.11 EGD90951.2 - 0.12 12.5 6.5 0.16 12.1 4.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) CDPS PF16715.5 EGD90951.2 - 0.16 11.6 2.0 0.17 11.5 1.6 1.3 1 1 0 1 1 1 0 Cyclodipeptide synthase DUF4355 PF14265.6 EGD90951.2 - 0.7 10.1 8.3 0.16 12.2 4.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Exonuc_VII_L PF02601.15 EGD90951.2 - 0.93 9.0 12.4 1.4 8.4 12.4 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit TBCA PF02970.16 EGD90951.2 - 1.1 9.6 8.2 0.57 10.6 2.6 2.7 2 1 0 2 2 2 0 Tubulin binding cofactor A zf-C4H2 PF10146.9 EGD90951.2 - 1.1 9.5 9.6 7.4 6.8 9.9 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein DUF349 PF03993.12 EGD90951.2 - 2 8.8 11.1 3.3 8.1 0.3 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) FUSC PF04632.12 EGD90951.2 - 2 6.8 9.4 0.16 10.4 3.2 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 EGD90951.2 - 8.8 4.1 6.7 2.5 5.9 2.6 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TIP49 PF06068.13 EGD90952.2 - 2.5e-54 184.8 0.1 3e-54 184.5 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGD90952.2 - 9.9e-22 76.9 0.1 7.9e-21 74.0 0.0 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA_22 PF13401.6 EGD90952.2 - 0.042 14.1 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGD90952.2 - 0.07 13.6 0.1 0.14 12.6 0.1 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 EGD90952.2 - 0.081 12.7 0.1 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_14 PF13173.6 EGD90952.2 - 0.099 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L28 PF00830.19 EGD90953.1 - 4e-16 58.9 0.6 7.3e-16 58.1 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L28 family Glyco_transf_34 PF05637.12 EGD90954.1 - 6.9e-58 196.2 0.0 8.5e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Steroid_dh PF02544.16 EGD90955.2 - 2.3e-29 102.3 0.0 3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EGD90955.2 - 1.7e-06 27.7 0.1 2.1e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EGD90955.2 - 7.6e-05 23.1 0.1 0.00014 22.2 0.1 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF913 PF06025.12 EGD90957.2 - 8.8e-126 419.8 0.0 8.8e-126 419.8 0.0 6.2 5 2 0 5 5 5 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 EGD90957.2 - 1e-110 370.6 5.7 1e-110 370.6 5.7 4.3 5 0 0 5 5 5 1 Domain of Unknown Function (DUF908) HECT PF00632.25 EGD90957.2 - 1.1e-93 314.1 0.0 1.9e-93 313.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 EGD90957.2 - 6.2e-30 101.7 21.6 4.6e-10 38.6 3.2 4.2 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 EGD90957.2 - 0.011 15.6 0.0 0.04 13.8 0.0 1.9 1 0 0 1 1 1 0 UBA/TS-N domain Pribosyltran_N PF13793.6 EGD90958.1 - 1.9e-47 160.0 0.3 6.2e-45 151.9 0.1 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGD90958.1 - 5.4e-44 150.4 1.0 4.4e-37 127.9 0.4 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGD90958.1 - 8.2e-19 67.7 0.5 9.3e-18 64.3 0.3 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGD90958.1 - 0.002 17.6 0.1 0.004 16.6 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ribosomal_S6e PF01092.19 EGD90959.1 - 2.2e-56 189.2 0.0 4.7e-56 188.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e SNF2_N PF00176.23 EGD90962.2 - 1e-27 96.8 0.0 8.9e-24 83.8 0.0 2.5 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EGD90962.2 - 1.2e-08 35.3 0.0 3.4e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PRK PF00485.18 EGD90963.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 EGD90963.1 - 0.0003 21.3 0.0 0.00048 20.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGD90963.1 - 0.0011 19.4 0.1 0.002 18.5 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGD90963.1 - 0.0061 17.1 0.1 0.03 14.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGD90963.1 - 0.039 14.2 1.3 0.1 12.8 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGD90963.1 - 0.097 13.2 3.0 0.45 11.0 3.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGD90963.1 - 0.12 12.7 0.2 0.41 10.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain NAD_binding_4 PF07993.12 EGD90964.1 - 9.2e-72 241.3 0.0 1.3e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGD90964.1 - 3.2e-70 236.9 0.0 4.7e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EGD90964.1 - 6.9e-10 38.8 0.0 1.7e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 EGD90964.1 - 2.6e-09 36.3 0.2 1.8e-08 33.6 0.2 2.1 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EGD90964.1 - 3.4e-09 36.9 0.0 8e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EGD90964.1 - 0.00071 18.7 0.0 0.0025 16.9 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EGD90964.1 - 0.00084 20.3 0.0 0.0038 18.2 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 EGD90964.1 - 0.0016 18.4 0.0 0.035 14.0 0.0 2.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGD90964.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGD90964.1 - 0.12 11.4 0.0 0.45 9.6 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain FAD_binding_5 PF00941.21 EGD90965.2 - 1.6e-41 141.9 0.0 2.6e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EGD90965.2 - 6e-34 116.3 0.0 1.6e-33 114.9 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 EGD90965.2 - 1.6e-29 102.5 0.0 3.7e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Ald_Xan_dh_C2 PF02738.18 EGD90965.2 - 3e-18 65.6 0.1 4.3e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase DUF3665 PF12427.8 EGD90967.1 - 0.00063 19.4 0.1 0.87 9.3 0.1 2.5 2 0 0 2 2 2 2 Branched-chain amino acid aminotransferase HHH_3 PF12836.7 EGD90967.1 - 0.05 13.9 0.0 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif KH_1 PF00013.29 EGD90969.2 - 6.5e-33 112.4 1.2 7.8e-16 57.7 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 EGD90969.2 - 6.7e-07 29.0 0.4 0.0013 18.5 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 EGD90969.2 - 2.9e-06 27.1 0.1 0.0054 16.6 0.0 2.5 2 0 0 2 2 2 2 KH domain Hamartin PF04388.12 EGD90969.2 - 0.034 12.8 2.0 0.041 12.6 2.0 1.1 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 EGD90969.2 - 0.19 11.7 21.4 0.31 11.0 21.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 EGD90969.2 - 2.8 6.6 6.9 4 6.1 6.9 1.2 1 0 0 1 1 1 0 Presenilin Aminotran_1_2 PF00155.21 EGD90970.1 - 1.6e-70 238.1 0.0 1.8e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGD90970.1 - 8.4e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGD90970.1 - 0.00018 20.6 0.1 0.0022 17.0 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGD90970.1 - 0.00022 19.9 0.0 0.00048 18.8 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGD90970.1 - 0.01 15.2 0.0 0.021 14.1 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MgsA_C PF12002.8 EGD90972.1 - 1.4e-58 197.6 0.1 2.3e-58 196.8 0.1 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EGD90972.1 - 4.1e-24 84.7 0.7 8.8e-24 83.7 0.7 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EGD90972.1 - 5.1e-14 52.8 0.0 1.2e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGD90972.1 - 2.2e-11 43.8 0.0 4.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EGD90972.1 - 9.2e-06 25.2 0.2 0.044 13.2 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGD90972.1 - 3.9e-05 23.7 0.0 0.0012 18.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGD90972.1 - 6e-05 22.8 0.0 0.0036 17.0 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EGD90972.1 - 9.3e-05 22.9 0.2 0.038 14.4 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_3 PF07726.11 EGD90972.1 - 0.00033 20.5 0.0 0.0009 19.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGD90972.1 - 0.00084 19.6 0.1 0.0044 17.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGD90972.1 - 0.0014 17.8 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EGD90972.1 - 0.0021 18.1 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGD90972.1 - 0.0056 16.7 0.1 0.51 10.3 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 EGD90972.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EGD90972.1 - 0.022 14.5 0.2 0.086 12.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 EGD90972.1 - 0.027 13.7 0.1 0.054 12.7 0.1 1.3 1 1 0 1 1 1 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 EGD90972.1 - 0.035 14.2 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PIF1 PF05970.14 EGD90972.1 - 0.036 13.2 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase NACHT PF05729.12 EGD90972.1 - 0.056 13.4 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EGD90972.1 - 0.074 12.8 0.1 5.1 6.9 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EGD90972.1 - 0.094 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGD90972.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 EGD90972.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 EGD90972.1 - 0.12 12.9 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGD90972.1 - 0.15 12.4 0.2 0.57 10.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGD90972.1 - 0.15 11.9 0.0 9.7 6.0 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_13 PF13166.6 EGD90972.1 - 0.2 10.3 0.1 0.39 9.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain EF-hand_7 PF13499.6 EGD90973.1 - 3.2e-16 59.5 0.6 5.3e-10 39.6 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGD90973.1 - 1.3e-14 52.5 1.5 1.8e-05 23.9 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGD90973.1 - 1.8e-13 49.2 3.4 1.8e-05 24.3 0.2 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EGD90973.1 - 1.9e-11 43.6 1.3 1.3e-08 34.6 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 EGD90973.1 - 0.0063 16.5 0.0 0.021 14.7 0.0 1.7 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF3572 PF12096.8 EGD90973.1 - 0.024 14.8 0.1 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) EF-hand_5 PF13202.6 EGD90973.1 - 0.034 13.6 4.2 1.4 8.5 0.1 2.7 3 0 0 3 3 3 0 EF hand EFhand_Ca_insen PF08726.10 EGD90973.1 - 0.16 12.1 0.3 0.55 10.4 0.0 2.0 2 1 1 3 3 3 0 Ca2+ insensitive EF hand Reprolysin_5 PF13688.6 EGD90974.2 - 8.9e-58 195.7 6.6 8.9e-58 195.7 6.6 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EGD90974.2 - 4.9e-46 157.1 1.8 1.2e-45 155.8 1.8 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EGD90974.2 - 5.1e-43 147.1 1.8 9.9e-43 146.1 1.8 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EGD90974.2 - 9.9e-15 55.1 36.6 9.9e-15 55.1 36.6 4.5 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 EGD90974.2 - 2.8e-11 44.0 0.1 8.5e-11 42.4 0.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 EGD90974.2 - 3.4e-07 30.7 1.6 3.4e-07 30.7 1.6 5.4 2 1 2 4 4 4 1 ADAM cysteine-rich domain IMS PF00817.20 EGD90975.2 - 2.1e-16 60.2 0.0 3.6e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EGD90975.2 - 2.4e-16 60.5 0.2 1e-15 58.4 0.1 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EGD90975.2 - 0.039 14.3 0.1 0.38 11.2 0.0 2.4 2 0 0 2 2 2 0 IMS family HHH motif KRAP_IP3R_bind PF14722.6 EGD90975.2 - 0.15 11.8 0.1 0.54 10.0 0.0 1.8 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain HHH_5 PF14520.6 EGD90975.2 - 0.19 12.4 0.1 2.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain C2 PF00168.30 EGD90977.1 - 5.6e-29 100.5 0.0 2.9e-17 62.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain GET2 PF08690.10 EGD90978.1 - 6.9e-09 35.8 0.0 1.7e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 GET complex subunit GET2 HTH_24 PF13412.6 EGD90978.1 - 0.031 13.8 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AMP-binding PF00501.28 EGD90979.1 - 1.1e-89 301.0 0.0 1.4e-89 300.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD90979.1 - 3.2e-27 95.3 1.1 1.7e-25 89.8 1.3 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGD90979.1 - 7.2e-16 57.8 0.0 1.8e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus F-box-like PF12937.7 EGD90980.1 - 0.024 14.5 0.2 0.085 12.8 0.2 2.0 1 0 0 1 1 1 0 F-box-like zf-C3Hc3H PF13891.6 EGD90980.1 - 0.91 9.9 7.2 0.2 12.1 2.7 2.2 2 1 0 2 2 2 0 Potential DNA-binding domain Nup96 PF12110.8 EGD90981.2 - 1e-78 264.4 0.0 1.7e-78 263.7 0.0 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EGD90981.2 - 2.5e-52 177.0 0.0 5e-52 176.0 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase DUF2336 PF10098.9 EGD90981.2 - 0.026 14.0 0.0 0.071 12.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) Complex1_51K PF01512.17 EGD90982.2 - 6.2e-48 162.5 0.0 1e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EGD90982.2 - 3.1e-29 100.9 2.0 4e-29 100.5 0.3 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EGD90982.2 - 8.4e-09 35.2 0.0 2.7e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 SLBB domain SET PF00856.28 EGD90983.1 - 2.8e-05 24.6 0.0 6.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 SET domain SAPS PF04499.15 EGD90984.2 - 6.8e-60 203.2 0.6 1e-59 202.6 0.6 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Cauli_DNA-bind PF03310.13 EGD90984.2 - 0.056 13.5 0.1 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Snf7 PF03357.21 EGD90985.1 - 8.4e-44 149.2 12.8 1e-43 148.9 12.8 1.1 1 0 0 1 1 1 1 Snf7 DUF3584 PF12128.8 EGD90985.1 - 0.00032 18.4 4.8 0.00044 17.9 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Atg14 PF10186.9 EGD90985.1 - 0.00077 18.6 1.6 0.00095 18.3 1.6 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 CLZ PF16526.5 EGD90985.1 - 0.0014 18.9 2.1 0.47 10.8 0.0 3.4 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 EGD90985.1 - 0.012 16.1 5.5 0.41 11.1 2.0 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.6 EGD90985.1 - 0.012 15.3 7.3 0.013 15.3 4.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HsbA PF12296.8 EGD90985.1 - 0.069 13.6 0.3 0.38 11.2 0.3 2.0 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Alpha-2-MRAP_C PF06401.11 EGD90985.1 - 0.095 12.7 2.3 0.16 11.9 1.0 1.9 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF948 PF06103.11 EGD90985.1 - 0.13 12.5 0.6 0.66 10.3 0.6 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 EGD90985.1 - 0.26 11.7 5.0 33 5.0 0.8 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 EGD90985.1 - 0.3 11.4 6.4 0.57 10.5 0.1 3.2 2 2 0 2 2 2 0 ABC transporter C-terminal domain Vps51 PF08700.11 EGD90985.1 - 1.6 8.9 6.3 2.7 8.1 0.6 3.1 2 1 1 3 3 3 0 Vps51/Vps67 DASH_Dam1 PF08653.10 EGD90985.1 - 1.8 8.4 3.6 22 5.0 0.3 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF4094 PF13334.6 EGD90985.1 - 2.8 8.4 5.0 12 6.4 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) SlyX PF04102.12 EGD90985.1 - 5.6 7.7 10.4 11 6.7 1.7 3.6 1 1 2 3 3 3 0 SlyX APH PF01636.23 EGD90987.2 - 3.9e-08 33.5 0.1 8.1e-08 32.5 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD90987.2 - 4.4e-05 23.2 0.0 6.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGD90987.2 - 0.097 12.0 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family GFO_IDH_MocA PF01408.22 EGD90988.2 - 1.8e-16 61.1 0.3 3.8e-16 60.0 0.2 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold RraA-like PF03737.15 EGD90991.1 - 1.9e-31 109.2 0.1 2.5e-31 108.9 0.1 1.1 1 0 0 1 1 1 1 Aldolase/RraA NTP_transf_3 PF12804.7 EGD90991.1 - 0.0038 17.6 0.2 0.055 13.8 0.1 2.1 1 1 0 2 2 2 1 MobA-like NTP transferase domain Acetyltransf_2 PF00797.17 EGD90992.1 - 1.4e-40 139.6 0.0 2.1e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase MWFE PF15879.5 EGD90993.2 - 4.5e-18 65.2 0.0 5.2e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit ABC_tran PF00005.27 EGD90993.2 - 0.16 12.5 0.0 0.17 12.4 0.0 1.1 1 0 0 1 1 1 0 ABC transporter MOZ_SAS PF01853.18 EGD90994.1 - 7.6e-75 250.5 0.0 1.2e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGD90994.1 - 1.9e-21 75.4 3.2 4.8e-21 74.1 3.2 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 EGD90994.1 - 6.2e-08 32.6 11.9 2e-07 31.0 11.9 2.0 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 EGD90994.1 - 0.0028 17.5 11.7 0.0028 17.5 11.7 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EGD90994.1 - 0.01 15.3 4.2 0.01 15.3 4.2 2.2 2 0 0 2 2 2 0 PHD-finger zf-Sec23_Sec24 PF04810.15 EGD90994.1 - 0.47 10.5 5.0 2.1 8.4 1.9 2.9 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Velvet PF11754.8 EGD90997.1 - 3.5e-47 161.5 0.3 7.3e-33 114.6 0.1 3.6 2 1 2 4 4 4 2 Velvet factor Pro_CA PF00484.19 EGD90999.2 - 2e-43 148.4 0.1 2.6e-43 148.0 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase EZH2_WD-Binding PF11616.8 EGD91000.2 - 0.027 14.6 0.2 0.059 13.5 0.2 1.6 1 0 0 1 1 1 0 WD repeat binding protein EZH2 PDDEXK_2 PF12784.7 EGD91000.2 - 0.06 12.9 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase DBD_Tnp_Hermes PF10683.9 EGD91001.1 - 0.03 14.0 0.1 0.063 13.0 0.1 1.4 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain Mannosyl_trans2 PF04188.13 EGD91003.2 - 3.8e-54 184.7 14.2 5e-54 184.3 14.2 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) BLM10_mid PF16507.5 EGD91004.2 - 8.1e-210 697.9 0.0 1.7e-209 696.9 0.0 1.6 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EGD91004.2 - 2e-19 69.3 0.0 1.1e-18 66.9 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) CLASP_N PF12348.8 EGD91004.2 - 0.0042 16.7 0.2 3.2 7.2 0.0 3.3 4 0 0 4 4 4 2 CLASP N terminal HEAT_2 PF13646.6 EGD91004.2 - 0.022 15.2 0.1 14 6.2 0.0 3.4 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.22 EGD91004.2 - 0.035 14.4 0.5 3.4 8.2 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat MOSC PF03473.17 EGD91005.1 - 5.7e-05 23.2 0.0 8.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain V_ATPase_I PF01496.19 EGD91006.1 - 0 1075.8 0.1 0 1075.6 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 EGD91006.1 - 0.00065 19.7 0.2 0.002 18.2 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) CheZ PF04344.13 EGD91006.1 - 0.012 15.5 5.0 0.33 10.9 0.5 2.4 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF4988 PF16378.5 EGD91006.1 - 0.12 12.0 0.2 0.29 10.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF1664 PF07889.12 EGD91006.1 - 0.15 12.1 3.9 10 6.1 0.1 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) Tektin PF03148.14 EGD91006.1 - 0.24 10.1 7.9 0.25 10.0 2.5 2.2 2 0 0 2 2 2 0 Tektin family Filament PF00038.21 EGD91006.1 - 0.28 10.7 9.7 2.7 7.5 0.1 2.4 2 1 0 2 2 2 0 Intermediate filament protein DUF16 PF01519.16 EGD91006.1 - 0.32 11.5 3.0 8.5 6.9 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function DUF16 CdvA PF18822.1 EGD91006.1 - 0.35 10.7 5.5 15 5.5 0.1 3.4 2 1 1 3 3 3 0 CdvA-like coiled-coil domain BLOC1_2 PF10046.9 EGD91006.1 - 0.63 10.4 4.4 3.2 8.1 1.2 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fmp27_WPPW PF10359.9 EGD91006.1 - 1 8.1 5.0 0.4 9.5 1.5 1.8 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain FapA PF03961.13 EGD91006.1 - 2.2 6.8 6.1 0.34 9.5 0.8 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A Nup54 PF13874.6 EGD91006.1 - 2.4 8.2 5.7 3 7.9 1.7 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF3552 PF12072.8 EGD91006.1 - 3.4 7.1 7.0 18 4.7 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) HMMR_N PF15905.5 EGD91006.1 - 4.5 6.7 6.8 2.2 7.7 2.2 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DivIC PF04977.15 EGD91006.1 - 6.3 6.7 5.8 2 8.2 0.3 2.9 3 0 0 3 3 3 0 Septum formation initiator Sugar_tr PF00083.24 EGD91007.2 - 1.5e-67 228.5 20.6 5.1e-49 167.4 2.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGD91007.2 - 1.7e-17 63.4 39.2 6.4e-15 54.9 17.7 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily HN PF00423.19 EGD91007.2 - 0.19 10.5 0.1 0.27 10.0 0.1 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase HlyIII PF03006.20 EGD91008.2 - 5.1e-16 59.1 5.8 5.9e-16 58.9 5.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related Lys_export PF03956.13 EGD91008.2 - 0.072 12.6 2.4 0.097 12.2 2.4 1.2 1 0 0 1 1 1 0 Lysine exporter LysO Cation_ATPase PF13246.6 EGD91009.2 - 5.3e-18 64.9 0.0 1e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGD91009.2 - 2.4e-15 57.4 0.0 7.7e-15 55.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EGD91009.2 - 7.8e-08 32.2 0.1 1.5e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 EGD91009.2 - 0.0002 21.2 1.4 0.0034 17.2 1.6 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.8 EGD91010.1 - 2.6e-40 138.4 0.3 3.4e-40 138.0 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD91010.1 - 2.3e-07 30.8 11.1 3.6e-07 30.2 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FBPase PF00316.20 EGD91012.1 - 4.2e-69 231.8 0.1 5.4e-69 231.5 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Aha1_N PF09229.11 EGD91014.1 - 2.4e-40 137.9 0.6 2.4e-40 137.9 0.6 1.5 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EGD91014.1 - 4.1e-19 69.0 0.1 7.2e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Drc1-Sld2 PF11719.8 EGD91014.1 - 0.28 10.7 2.0 0.37 10.3 2.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Glyco_hydro_15 PF00723.21 EGD91015.1 - 1.1e-92 311.2 0.1 1.3e-92 310.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EGD91015.1 - 9.1e-28 96.0 0.0 2e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain ADH_zinc_N_2 PF13602.6 EGD91016.1 - 4.9e-23 82.6 0.0 8.8e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGD91016.1 - 4.2e-15 55.9 0.2 6.5e-15 55.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGD91016.1 - 0.014 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PGM_PMM_II PF02879.16 EGD91016.1 - 0.13 12.9 0.0 0.58 10.8 0.0 2.1 3 0 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Sacchrp_dh_C PF16653.5 EGD91018.1 - 2.1e-96 323.1 0.0 4.5e-96 322.0 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EGD91018.1 - 7.5e-23 81.2 0.7 1.3e-22 80.4 0.7 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EGD91018.1 - 1.5e-06 28.3 0.2 3e-06 27.4 0.2 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EGD91018.1 - 0.0008 19.3 0.8 0.013 15.4 0.2 2.1 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_7 PF13241.6 EGD91018.1 - 0.045 14.2 0.1 0.09 13.2 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Prenyltransf PF01255.19 EGD91019.1 - 1.3e-81 273.4 0.0 3e-81 272.2 0.0 1.6 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Tmemb_cc2 PF10267.9 EGD91019.1 - 0.0091 15.2 0.8 0.011 14.9 0.8 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Apt1 PF10351.9 EGD91019.1 - 0.062 12.1 1.4 0.082 11.7 1.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SelP_N PF04592.14 EGD91019.1 - 0.42 10.0 8.4 0.65 9.4 8.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Acyl-thio_N PF12590.8 EGD91024.2 - 0.052 14.1 0.0 11 6.6 0.0 2.1 2 0 0 2 2 2 0 Acyl-ATP thioesterase Vps36_ESCRT-II PF11605.8 EGD91025.2 - 0.00036 20.6 0.0 0.12 12.6 0.0 2.3 1 1 1 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 UCR_hinge PF02320.16 EGD91026.2 - 2e-17 63.1 15.9 9.5e-13 48.2 4.9 2.6 2 1 1 3 3 2 2 Ubiquinol-cytochrome C reductase hinge protein DUF4211 PF13926.6 EGD91026.2 - 0.0088 16.1 0.9 0.013 15.6 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) CDC45 PF02724.14 EGD91026.2 - 0.2 9.9 4.2 0.2 9.9 4.2 1.0 1 0 0 1 1 1 0 CDC45-like protein ORC_WH_C PF18137.1 EGD91026.2 - 0.3 11.2 4.4 0.089 12.9 1.6 1.6 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Radial_spoke PF04712.12 EGD91026.2 - 0.3 10.0 8.0 0.32 9.9 8.0 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Zip PF02535.22 EGD91026.2 - 0.41 9.8 1.8 0.5 9.5 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_60s PF00428.19 EGD91026.2 - 0.44 11.2 14.7 1 10.0 14.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nop14 PF04147.12 EGD91026.2 - 0.75 7.9 10.6 0.78 7.9 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.8 EGD91026.2 - 0.77 8.5 4.2 0.79 8.4 4.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RRN3 PF05327.11 EGD91026.2 - 1 7.8 4.8 1.2 7.6 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 EGD91026.2 - 2.4 7.5 12.3 2.7 7.3 12.3 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EGD91026.2 - 7.8 4.5 15.4 8.1 4.4 15.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 EGD91026.2 - 9.2 5.5 14.2 11 5.2 14.2 1.0 1 0 0 1 1 1 0 BUD22 MFS_1 PF07690.16 EGD91027.2 - 1.8e-17 63.3 28.0 2.7e-17 62.8 28.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Uds1 PF15456.6 EGD91028.2 - 5.5e-39 133.3 1.1 5.5e-39 133.3 1.1 6.1 4 2 2 6 6 6 2 Up-regulated During Septation TPR_MLP1_2 PF07926.12 EGD91028.2 - 6.9e-05 22.9 17.9 0.00081 19.5 14.8 7.6 6 1 3 9 9 9 3 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 EGD91028.2 - 0.0031 17.5 7.4 0.0031 17.5 7.4 8.6 10 1 1 11 11 11 1 TATA element modulatory factor 1 DNA binding Filament PF00038.21 EGD91028.2 - 0.0039 16.8 9.0 0.0039 16.8 9.0 5.7 2 2 0 3 3 3 1 Intermediate filament protein DUF4407 PF14362.6 EGD91028.2 - 0.49 9.7 51.9 0.25 10.6 14.6 4.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) Taxilin PF09728.9 EGD91028.2 - 0.82 8.8 49.4 0.057 12.6 23.5 5.0 3 1 1 4 4 4 0 Myosin-like coiled-coil protein ApoO PF09769.9 EGD91028.2 - 0.92 9.5 12.2 5.7 6.9 1.7 4.6 5 2 2 7 7 7 0 Apolipoprotein O Baculo_PEP_C PF04513.12 EGD91028.2 - 2.8 8.0 28.2 4.5 7.3 1.3 6.1 2 2 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EGD91028.2 - 4.8 7.4 38.8 12 6.1 6.5 6.0 4 1 2 6 6 6 0 Fibrinogen alpha/beta chain family WD40 PF00400.32 EGD91030.1 - 3.7e-27 94.0 14.1 0.00012 22.8 0.1 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 EGD91030.1 - 1.5e-11 44.0 0.3 3e-11 43.0 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD91030.1 - 2.1e-07 30.6 0.1 5.9e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EGD91030.1 - 0.00028 21.1 0.3 21 5.5 0.0 4.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGD91030.1 - 0.0019 18.2 0.0 3.9 7.6 0.0 3.7 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EGD91030.1 - 0.19 11.0 0.0 11 5.2 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain DNA_pol_phi PF04931.13 EGD91035.1 - 0.5 8.4 5.5 0.89 7.6 5.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 EGD91035.1 - 0.54 10.7 11.9 0.14 12.5 7.6 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EGD91035.1 - 5 6.3 18.6 0.013 14.9 8.2 1.8 2 0 0 2 2 2 0 NOA36 protein Sld5 PF05916.11 EGD91036.1 - 1.7e-19 70.3 0.0 2.3e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DUF3280 PF11684.8 EGD91037.2 - 0.65 10.4 2.3 1.3 9.5 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) YabA PF06156.13 EGD91037.2 - 1.3 9.7 8.1 2.6 8.7 8.1 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Spc7 PF08317.11 EGD91037.2 - 6.5 5.5 9.6 9.7 5.0 9.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Sod_Fe_C PF02777.18 EGD91039.1 - 3.5e-36 123.5 0.1 6.1e-36 122.7 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGD91039.1 - 3.7e-30 104.2 0.6 6.1e-30 103.5 0.6 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GCFC PF07842.12 EGD91040.1 - 1.2e-85 287.5 8.3 2e-85 286.7 8.3 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EGD91040.1 - 5e-16 58.3 0.5 9.7e-16 57.4 0.5 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGD91040.1 - 9.9e-07 28.8 0.2 9.9e-07 28.8 0.2 2.0 2 0 0 2 2 2 1 G-patch domain Scm3 PF10384.9 EGD91040.1 - 0.072 12.9 0.4 0.25 11.1 0.4 1.9 1 0 0 1 1 1 0 Centromere protein Scm3 NICE-3 PF07406.11 EGD91041.1 - 0.0027 17.7 0.0 0.0046 17.0 0.0 1.3 1 0 0 1 1 1 1 NICE-3 protein DUF4129 PF13559.6 EGD91041.1 - 0.047 14.0 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) DUF3810 PF12725.7 EGD91041.1 - 0.73 9.1 2.4 1.1 8.6 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Suc_Fer-like PF06999.12 EGD91042.2 - 2.6e-55 187.4 0.0 2.9e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like zf-C2H2 PF00096.26 EGD91043.2 - 1.2e-18 66.4 32.5 0.00015 22.0 1.4 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGD91043.2 - 1.9e-13 50.2 34.1 7.1e-06 26.2 0.5 5.9 5 1 1 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGD91043.2 - 1.9e-05 25.1 35.5 0.21 12.5 2.9 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger FOXP-CC PF16159.5 EGD91043.2 - 0.92 10.2 30.8 5.4 7.7 0.5 5.8 3 2 3 6 6 6 0 FOXP coiled-coil domain Zip PF02535.22 EGD91043.2 - 8.5 5.5 5.8 12 5.0 5.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter adh_short PF00106.25 EGD91045.2 - 2.1e-06 27.3 0.0 0.003 17.0 0.0 3.0 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGD91045.2 - 0.00025 20.7 0.0 0.1 12.2 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NTP_transferase PF00483.23 EGD91046.1 - 9e-25 87.7 0.0 1.9e-24 86.6 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 EGD91046.1 - 7.3e-19 66.7 16.4 4e-11 42.2 1.9 4.0 3 2 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGD91046.1 - 1.3e-06 28.0 1.1 1.3e-06 28.0 1.1 3.6 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EGD91046.1 - 0.0017 16.6 0.1 0.005 15.0 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) Peptidase_M41 PF01434.18 EGD91048.1 - 4.7e-54 183.1 0.1 8.2e-54 182.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGD91048.1 - 3.3e-42 144.0 0.0 7.2e-42 142.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD91048.1 - 9.4e-10 38.1 0.0 2.6e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGD91048.1 - 2.8e-05 24.2 0.0 8.1e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGD91048.1 - 7.1e-05 22.2 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EGD91048.1 - 0.00012 22.4 0.2 0.014 15.6 0.2 2.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGD91048.1 - 0.00012 22.5 3.1 0.00049 20.5 0.6 3.0 3 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 EGD91048.1 - 0.00053 19.8 0.0 0.0022 17.8 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGD91048.1 - 0.0017 18.5 0.0 0.0057 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGD91048.1 - 0.0058 16.8 0.0 0.019 15.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 EGD91048.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EGD91048.1 - 0.016 15.7 0.0 0.055 14.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EGD91048.1 - 0.018 14.6 1.7 0.76 9.3 0.2 2.4 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGD91048.1 - 0.024 14.1 0.3 0.045 13.1 0.3 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EGD91048.1 - 0.028 13.6 0.0 0.058 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase PF06745.13 EGD91048.1 - 0.054 12.8 0.0 1.6 8.0 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 EGD91048.1 - 0.057 13.7 0.4 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGD91048.1 - 0.072 13.0 0.4 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EGD91048.1 - 0.089 12.8 0.0 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EGD91048.1 - 0.089 12.8 0.0 0.44 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGD91048.1 - 0.16 12.4 0.2 0.46 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGD91048.1 - 0.19 11.0 0.8 0.72 9.1 0.5 2.0 1 1 1 2 2 2 0 Zeta toxin FGGY_C PF02782.16 EGD91050.2 - 5.4e-35 120.9 0.4 7e-35 120.6 0.4 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF3429 PF11911.8 EGD91051.1 - 1.7e-44 151.6 13.4 2.6e-44 151.0 13.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) VPS13_C PF16909.5 EGD91053.2 - 4.6e-76 254.5 3.9 4.7e-71 238.2 0.3 2.4 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 EGD91053.2 - 8.4e-07 29.2 0.0 3.9e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Transket_pyr PF02779.24 EGD91055.1 - 1.6e-66 223.4 0.0 2.8e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EGD91055.1 - 1.6e-56 190.2 0.0 2.7e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EGD91055.1 - 3e-56 190.6 0.0 4.6e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 EGD91055.1 - 3.1e-20 71.5 0.6 3.1e-20 71.5 0.6 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus ING PF12998.7 EGD91056.2 - 4.3e-10 40.1 0.0 9.3e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGD91056.2 - 0.0004 20.2 0.9 0.00071 19.4 0.9 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EGD91056.2 - 0.057 13.7 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF4504 PF14953.6 EGD91056.2 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) DUF1751 PF08551.10 EGD91057.1 - 0.0036 17.8 1.7 0.0051 17.4 0.5 1.9 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) PhoR PF11808.8 EGD91057.1 - 0.93 10.0 6.1 1.9 8.9 2.4 2.7 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR BSD PF03909.17 EGD91058.1 - 1.2e-23 82.8 7.8 1.2e-11 44.4 1.0 3.0 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 EGD91058.1 - 2.6e-23 82.2 0.0 6.2e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain PIN_8 PF18476.1 EGD91058.1 - 0.068 13.0 0.2 0.068 13.0 0.2 2.5 3 0 0 3 3 3 0 PIN like domain APH PF01636.23 EGD91060.1 - 6.5e-14 52.4 0.0 9.4e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD91060.1 - 5.7e-10 39.1 0.0 2.2e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase p450 PF00067.22 EGD91061.1 - 8e-48 163.3 0.0 6.2e-47 160.4 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 EGD91062.1 - 3.3e-58 197.5 49.4 4.1e-58 197.2 49.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD91062.1 - 1.4e-25 89.8 43.2 1.9e-25 89.4 43.2 1.0 1 0 0 1 1 1 1 Amino acid permease LRR19-TM PF15176.6 EGD91064.1 - 1.8 8.6 4.4 4.7 7.3 0.1 3.3 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain F-box-like PF12937.7 EGD91065.1 - 5.5e-05 23.0 0.2 0.00015 21.6 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EGD91065.1 - 0.00028 20.7 12.0 4.2 7.7 0.0 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 EGD91065.1 - 0.00065 20.0 14.0 0.057 13.9 0.2 5.7 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGD91065.1 - 0.0039 17.5 7.8 47 5.1 0.2 6.9 6 0 0 6 6 6 0 Leucine Rich Repeat F-box PF00646.33 EGD91065.1 - 0.047 13.6 1.7 0.3 11.0 1.7 2.4 1 1 0 1 1 1 0 F-box domain MRP-L46 PF11788.8 EGD91065.1 - 0.14 12.9 0.4 0.39 11.5 0.4 1.7 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Serglycin PF04360.12 EGD91066.2 - 0.81 9.6 4.2 0.5 10.3 1.4 2.0 2 0 0 2 2 2 0 Serglycin SUZ PF12752.7 EGD91068.2 - 2.4e-05 25.0 5.6 2.4e-05 25.0 5.6 3.7 2 2 0 2 2 2 1 SUZ domain MAP7 PF05672.11 EGD91068.2 - 0.91 9.2 14.3 1.9 8.1 14.3 1.5 1 1 0 1 1 1 0 MAP7 (E-MAP-115) family GST_N_3 PF13417.6 EGD91069.1 - 6.9e-20 71.2 0.0 1.6e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGD91069.1 - 6e-16 58.5 0.0 1.8e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGD91069.1 - 1.7e-07 31.5 0.0 3.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGD91069.1 - 1.7e-06 27.9 0.1 3.5e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGD91069.1 - 0.023 14.9 0.0 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGD91069.1 - 0.027 15.0 0.0 0.054 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EGD91069.1 - 0.076 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin ATP_bind_1 PF03029.17 EGD91071.2 - 3.3e-61 207.1 0.0 4.8e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EGD91071.2 - 0.0024 17.4 0.0 0.011 15.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGD91071.2 - 0.056 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B MeaB PF03308.16 EGD91071.2 - 0.059 12.3 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CwfJ_C_1 PF04677.15 EGD91072.1 - 6.8e-29 100.2 0.0 1.3e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EGD91072.1 - 8.2e-29 100.4 0.1 8.2e-29 100.4 0.1 2.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 FumaraseC_C PF10415.9 EGD91072.1 - 0.0028 18.0 1.6 2.2 8.8 0.1 3.1 3 0 0 3 3 3 2 Fumarase C C-terminus 2-Hacid_dh_C PF02826.19 EGD91073.2 - 3e-56 189.6 0.0 4.1e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGD91073.2 - 1.5e-08 34.4 0.0 1.9e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGD91073.2 - 0.00092 19.4 0.1 0.0014 18.9 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.18 EGD91074.1 - 1.4e-08 34.7 10.4 2.4e-08 33.9 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-U1 PF06220.12 EGD91075.1 - 2.1e-08 33.8 0.6 3.9e-08 32.9 0.6 1.5 1 0 0 1 1 1 1 U1 zinc finger ABC_tran_Xtn PF12848.7 EGD91075.1 - 7.8 6.6 14.2 2.8 8.0 0.8 2.7 3 0 0 3 3 3 0 ABC transporter CAP_GLY PF01302.25 EGD91076.1 - 3.6e-21 75.0 0.1 5.7e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 EGD91076.1 - 6.1e-14 51.9 9.6 0.022 15.2 0.6 5.4 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGD91076.1 - 6.4e-06 25.8 16.2 0.0054 16.5 1.6 5.2 5 2 0 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 EGD91076.1 - 0.00039 20.0 6.4 0.067 12.7 0.4 3.1 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 EGD91076.1 - 0.0088 16.0 9.3 4.8 7.5 0.0 5.8 7 0 0 7 7 7 2 Leucine Rich repeat MFS_1 PF07690.16 EGD91077.2 - 2.4e-15 56.3 22.4 1.2e-14 54.1 19.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SieB PF14163.6 EGD91077.2 - 0.62 9.5 2.9 1.8 8.0 0.1 2.7 3 0 0 3 3 3 0 Super-infection exclusion protein B Methyltransf_2 PF00891.18 EGD91078.1 - 2.6e-12 46.5 0.0 3.7e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGD91078.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_11 PF08241.12 EGD91079.1 - 6.9e-12 45.9 0.0 1.5e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD91079.1 - 6.7e-10 39.5 0.0 2e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD91079.1 - 3.5e-07 30.9 0.0 6.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD91079.1 - 0.00067 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD91079.1 - 0.038 13.8 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGD91079.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SF3A2 PF16835.5 EGD91080.1 - 3.3e-37 126.8 0.0 4.8e-37 126.2 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EGD91080.1 - 1.2e-05 25.5 0.5 2.1e-05 24.8 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 EGD91080.1 - 0.05 13.2 1.5 0.11 12.0 1.5 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.25 EGD91081.1 - 4.9e-56 190.0 0.0 8.3e-55 186.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD91081.1 - 8.4e-25 87.5 0.3 3.6e-19 69.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGD91081.1 - 4.8e-06 25.8 0.1 7e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGD91081.1 - 0.00026 21.0 0.2 0.038 13.9 0.2 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGD91081.1 - 0.00071 19.0 0.2 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGD91081.1 - 0.0016 17.9 0.0 0.0038 16.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGD91081.1 - 0.02 14.6 0.2 2.8 7.5 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NFACT-C PF11923.8 EGD91081.1 - 0.028 14.4 0.4 0.059 13.3 0.4 1.5 1 0 0 1 1 1 0 NFACT protein C-terminal domain Pkinase_fungal PF17667.1 EGD91081.1 - 0.041 12.7 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EGD91081.1 - 0.048 12.7 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PepX_N PF09168.10 EGD91081.1 - 0.058 13.8 0.6 0.12 12.7 0.6 1.5 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Pox_ser-thr_kin PF05445.11 EGD91081.1 - 0.075 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EGD91081.1 - 0.43 10.2 2.2 0.84 9.2 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Tim54 PF11711.8 EGD91082.1 - 7.8e-139 462.6 0.0 9.1e-139 462.4 0.0 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.8 EGD91083.2 - 2.3e-215 716.4 1.9 2.3e-215 716.4 1.9 1.7 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 EGD91083.2 - 2.5e-20 71.4 15.0 0.0012 19.5 1.6 9.9 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGD91083.2 - 2.5e-19 67.8 27.7 9.1e-05 22.3 0.5 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGD91083.2 - 4e-16 59.3 24.4 5.8e-05 23.5 0.0 6.9 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGD91083.2 - 2.2e-11 43.1 27.7 1.4e-05 24.7 0.6 8.6 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGD91083.2 - 2.3e-11 42.9 21.5 0.0003 20.8 0.3 7.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGD91083.2 - 4.6e-11 43.2 16.5 0.0025 18.4 1.7 7.5 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGD91083.2 - 7.1e-09 35.7 14.5 0.0016 18.6 0.0 5.9 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGD91083.2 - 1.3e-08 34.4 13.5 0.00038 20.1 1.4 6.1 6 0 0 6 6 6 2 TPR repeat ANAPC3 PF12895.7 EGD91083.2 - 9.8e-08 32.1 10.1 0.063 13.5 1.1 4.7 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGD91083.2 - 1.6e-07 31.5 21.8 0.068 13.5 0.5 7.2 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 EGD91083.2 - 1.1e-06 28.5 1.2 8.6e-05 22.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 EGD91083.2 - 1.4e-06 28.3 11.6 0.048 14.1 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGD91083.2 - 1.7e-06 27.5 9.7 0.0054 16.0 0.8 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 EGD91083.2 - 0.00043 20.7 2.8 0.0038 17.7 0.2 3.4 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 EGD91083.2 - 0.00067 20.1 17.2 0.15 12.8 0.2 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGD91083.2 - 0.00096 19.0 13.9 0.95 9.6 0.4 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_3 PF07720.12 EGD91083.2 - 0.0027 17.7 5.6 0.056 13.5 0.2 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 EGD91083.2 - 0.098 12.8 0.1 0.39 10.9 0.1 2.1 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.14 EGD91083.2 - 0.12 13.1 11.1 3.7 8.5 2.1 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGD91083.2 - 7.3 6.8 12.0 36 4.5 0.2 5.0 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Cid2 PF09774.9 EGD91084.1 - 1.3e-56 191.4 0.1 1.6e-56 191.2 0.1 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Fapy_DNA_glyco PF01149.24 EGD91085.1 - 4.4e-34 117.6 0.0 8.8e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EGD91085.1 - 8.8e-21 73.7 0.0 1.7e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Mitofilin PF09731.9 EGD91085.1 - 0.0038 16.1 7.7 0.0051 15.7 7.7 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein FbpA PF05833.11 EGD91085.1 - 0.0057 15.5 0.0 0.0093 14.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) GCP5-Mod21 PF14609.6 EGD91085.1 - 0.7 8.2 3.5 0.99 7.7 3.5 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Pol_alpha_B_N PF08418.10 EGD91085.1 - 3.3 7.6 12.8 4.6 7.1 12.8 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RR_TM4-6 PF06459.12 EGD91085.1 - 3.7 7.3 5.9 5.7 6.7 5.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2263 PF10021.9 EGD91086.1 - 6.6e-19 68.7 0.0 2.1e-18 67.1 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Fe_hyd_lg_C PF02906.14 EGD91087.2 - 6.8e-49 166.7 0.0 1e-48 166.2 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain fn3 PF00041.21 EGD91090.2 - 2.9e-12 46.7 1.2 3.4e-07 30.5 0.0 3.0 3 0 0 3 3 3 2 Fibronectin type III domain zf-NADH-PPase PF09297.11 EGD91090.2 - 0.00085 18.9 0.5 0.0023 17.6 0.5 1.8 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DNA_RNApol_7kD PF03604.13 EGD91091.1 - 2.2e-17 62.4 7.0 2.9e-17 62.0 7.0 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 EGD91091.1 - 0.0012 18.8 0.3 0.0013 18.8 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2318 PF10080.9 EGD91091.1 - 0.0037 17.4 0.2 0.0039 17.3 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) DUF2197 PF09963.9 EGD91091.1 - 0.0045 17.2 2.8 0.22 11.8 0.2 2.2 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) zinc-ribbon_6 PF10005.9 EGD91091.1 - 0.0055 17.4 0.5 0.0073 17.0 0.5 1.2 1 0 0 1 1 1 1 zinc-ribbon domain GFA PF04828.14 EGD91091.1 - 0.0078 16.5 1.0 1.3 9.4 0.1 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme TRL PF13146.6 EGD91091.1 - 0.0081 16.4 0.0 0.0094 16.2 0.0 1.2 1 0 0 1 1 1 1 TRL-like protein family Zn_ribbon_SprT PF17283.2 EGD91091.1 - 0.011 15.7 0.4 0.015 15.2 0.4 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain DZR PF12773.7 EGD91091.1 - 0.012 15.6 0.3 0.017 15.1 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EGD91091.1 - 0.015 15.4 0.7 0.027 14.6 0.7 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 EGD91091.1 - 0.019 14.9 0.4 0.026 14.5 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 EGD91091.1 - 0.021 14.4 1.6 1.4 8.6 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF1451 PF07295.11 EGD91091.1 - 0.023 14.7 0.3 0.025 14.6 0.3 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF2757 PF10955.8 EGD91091.1 - 0.037 14.3 0.6 0.046 14.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Zn_ribbon_recom PF13408.6 EGD91091.1 - 0.12 12.9 5.4 2.1 8.9 0.9 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF951 PF06107.11 EGD91091.1 - 0.3 11.0 3.3 0.97 9.4 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) TFIIS_C PF01096.18 EGD91091.1 - 0.92 9.4 4.9 7.5 6.5 0.7 2.5 1 1 0 2 2 2 0 Transcription factor S-II (TFIIS) Glycos_transf_3 PF00591.21 EGD91092.1 - 2.9e-55 187.6 0.0 1.2e-52 179.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EGD91092.1 - 3e-06 27.0 1.3 4e-06 26.6 0.3 1.7 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain F-box PF00646.33 EGD91094.1 - 0.054 13.4 0.3 0.16 11.9 0.2 1.8 2 0 0 2 2 2 0 F-box domain DUF1598 PF07643.11 EGD91095.1 - 0.08 13.2 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) Ribosomal_L10 PF00466.20 EGD91095.1 - 0.085 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L10 PI-PLC-X PF00388.19 EGD91096.1 - 7.4e-11 41.8 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain 2-oxoacid_dh PF00198.23 EGD91097.1 - 2.1e-81 272.8 0.7 2.8e-81 272.4 0.7 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 EGD91097.1 - 9.8e-14 51.4 0.0 2.3e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.22 EGD91097.1 - 3e-12 46.2 0.0 6.9e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Peptidase_C14 PF00656.22 EGD91098.2 - 1.2e-61 208.8 0.0 1.7e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Acetyltransf_3 PF13302.7 EGD91099.2 - 0.0001 23.0 0.0 0.00013 22.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_18 PF13238.6 EGD91100.1 - 4.9e-11 43.3 0.0 3.5e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGD91100.1 - 2.4e-10 40.7 0.1 1e-09 38.7 0.0 2.0 2 1 0 2 2 1 1 AAA domain SKI PF01202.22 EGD91100.1 - 2.7e-10 40.6 0.1 4.3e-09 36.7 0.1 2.2 1 1 0 1 1 1 1 Shikimate kinase Rad17 PF03215.15 EGD91100.1 - 1e-06 28.8 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_17 PF13207.6 EGD91100.1 - 9.1e-06 26.1 0.0 0.0039 17.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 EGD91100.1 - 9.6e-06 25.6 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA PF00004.29 EGD91100.1 - 6.4e-05 23.4 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGD91100.1 - 0.00024 21.1 0.0 0.00067 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGD91100.1 - 0.00036 20.8 0.1 0.0011 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EGD91100.1 - 0.00046 20.0 0.0 0.0012 18.6 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase NACHT PF05729.12 EGD91100.1 - 0.00091 19.2 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGD91100.1 - 0.00094 19.6 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EGD91100.1 - 0.0016 18.8 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Cytidylate_kin2 PF13189.6 EGD91100.1 - 0.0022 18.1 0.0 0.022 14.9 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase-like family APS_kinase PF01583.20 EGD91100.1 - 0.0041 17.0 0.0 0.016 15.1 0.0 1.9 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_28 PF13521.6 EGD91100.1 - 0.0045 17.3 0.0 0.0084 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EGD91100.1 - 0.0085 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EGD91100.1 - 0.0091 15.8 0.1 0.019 14.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGD91100.1 - 0.01 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EGD91100.1 - 0.011 15.7 0.0 0.024 14.5 0.0 1.6 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EGD91100.1 - 0.014 14.7 0.0 0.058 12.7 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 EGD91100.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain tRNA_lig_kinase PF08303.11 EGD91100.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.6 2 0 0 2 2 1 0 tRNA ligase kinase domain PRK PF00485.18 EGD91100.1 - 0.015 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 EGD91100.1 - 0.016 15.7 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 EGD91100.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Viral_helicase1 PF01443.18 EGD91100.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 EGD91100.1 - 0.037 13.5 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Herpes_Helicase PF02689.14 EGD91100.1 - 0.045 11.7 0.0 0.06 11.3 0.0 1.1 1 0 0 1 1 1 0 Helicase DUF2075 PF09848.9 EGD91100.1 - 0.049 12.9 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 EGD91100.1 - 0.052 12.9 0.1 0.13 11.6 0.1 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EGD91100.1 - 0.053 13.3 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 EGD91100.1 - 0.054 13.4 0.0 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 EGD91100.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ADK PF00406.22 EGD91100.1 - 0.075 13.1 0.1 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase AAA_25 PF13481.6 EGD91100.1 - 0.082 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGD91100.1 - 0.092 13.1 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGD91100.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain CoaE PF01121.20 EGD91100.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase PduV-EutP PF10662.9 EGD91100.1 - 0.17 11.6 0.0 0.5 10.1 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Vps26 PF03643.15 EGD91102.1 - 1.2e-128 427.9 0.1 1.4e-128 427.7 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EGD91102.1 - 0.00055 20.0 0.1 2.1 8.4 0.0 3.3 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Sec7_N PF12783.7 EGD91103.2 - 3.1e-40 137.7 19.6 9e-40 136.2 5.3 4.8 4 1 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EGD91103.2 - 4e-36 124.3 3.5 4e-36 124.3 3.5 4.7 5 1 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 EGD91103.2 - 1.2e-19 70.1 2.2 1.2e-19 70.1 2.2 2.6 3 1 0 3 3 3 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 EGD91103.2 - 0.00088 19.1 4.6 0.011 15.5 0.0 4.9 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Gly_acyl_tr_N PF06021.11 EGD91103.2 - 0.0025 18.0 0.4 0.093 12.8 0.0 2.7 2 0 0 2 2 2 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Antimicrobial19 PF08225.11 EGD91103.2 - 0.097 12.3 0.0 0.47 10.1 0.0 2.2 1 0 0 1 1 1 0 Pseudin antimicrobial peptide UQ_con PF00179.26 EGD91104.1 - 6.3e-18 64.8 0.0 6.9e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Dodecin PF07311.12 EGD91105.2 - 0.098 12.9 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Dodecin GST_C PF00043.25 EGD91106.1 - 1.2e-16 60.7 0.1 2.6e-16 59.6 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGD91106.1 - 6.5e-14 52.0 0.0 1.9e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGD91106.1 - 9.6e-11 41.9 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGD91106.1 - 2.9e-10 40.3 0.0 5.5e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGD91106.1 - 9.1e-09 35.2 0.3 2.6e-08 33.8 0.1 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGD91106.1 - 1.2e-08 35.0 0.0 2.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGD91106.1 - 0.0038 17.8 0.0 0.007 16.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Putative_PNPOx PF01243.20 EGD91107.1 - 3.1e-06 27.3 0.0 5.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RWD PF05773.22 EGD91108.1 - 5.5e-26 91.1 2.0 1.1e-25 90.1 2.0 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 EGD91108.1 - 0.00038 20.9 15.5 0.0018 18.7 15.1 2.3 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF1682 PF07946.14 EGD91108.1 - 0.001 18.3 7.8 0.0014 17.9 7.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) ketoacyl-synt PF00109.26 EGD91108.1 - 0.2 11.2 0.2 0.29 10.7 0.2 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain MPM1 PF17234.2 EGD91108.1 - 3.4 7.9 10.1 1.5 9.0 7.4 1.6 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 TPR_2 PF07719.17 EGD91109.1 - 5e-13 48.1 0.0 0.0001 22.2 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGD91109.1 - 3.1e-11 43.6 0.0 8.2e-06 26.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGD91109.1 - 2.3e-10 40.4 0.3 0.18 12.7 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGD91109.1 - 2.1e-09 37.5 0.0 7.3e-06 26.2 0.0 4.0 4 2 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGD91109.1 - 3e-09 36.3 0.0 0.00027 20.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGD91109.1 - 3.5e-09 36.2 0.0 1e-05 25.3 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGD91109.1 - 1.5e-07 31.9 0.0 0.43 11.3 0.0 3.5 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGD91109.1 - 7.1e-06 26.1 0.1 2.1 8.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGD91109.1 - 3.6e-05 23.5 0.0 0.21 11.7 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGD91109.1 - 7.1e-05 22.4 0.0 0.00072 19.2 0.0 2.4 2 0 0 2 2 2 1 TPR repeat ANAPC3 PF12895.7 EGD91109.1 - 0.00021 21.5 0.0 0.3 11.3 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGD91109.1 - 0.00058 19.6 0.1 11 6.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGD91109.1 - 0.0094 15.7 0.0 0.55 9.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 EGD91109.1 - 0.011 15.1 0.0 0.68 9.2 0.0 2.4 2 0 0 2 2 2 0 MalT-like TPR region TPR_5 PF12688.7 EGD91109.1 - 0.02 15.1 0.0 0.28 11.5 0.0 2.5 1 1 0 2 2 2 0 Tetratrico peptide repeat TPR_17 PF13431.6 EGD91109.1 - 0.023 15.0 0.0 92 3.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EGD91109.1 - 0.046 13.1 0.0 3.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_4 PF07721.14 EGD91109.1 - 0.11 13.2 0.9 2.9 8.8 0.0 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGD91109.1 - 0.11 12.0 0.6 5.6 6.5 0.1 2.8 2 0 0 2 2 2 0 SHNi-TPR TPR_6 PF13174.6 EGD91109.1 - 0.18 12.5 0.1 12 6.7 0.0 3.6 5 0 0 5 5 3 0 Tetratricopeptide repeat SIR2 PF02146.17 EGD91110.1 - 7.4e-60 201.9 0.0 1.1e-59 201.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EGD91110.1 - 7e-07 29.1 0.1 1.2e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EGD91110.1 - 0.0006 19.6 0.3 1 9.1 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF2985 PF11204.8 EGD91111.2 - 5.8e-18 64.8 5.8 1.3e-17 63.7 5.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) LTXXQ PF07813.12 EGD91111.2 - 0.0019 18.9 0.3 0.0019 18.9 0.3 2.4 2 0 0 2 2 2 1 LTXXQ motif family protein NARP1 PF12569.8 EGD91111.2 - 0.45 9.4 7.0 0.87 8.4 7.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.10 EGD91111.2 - 10 6.2 9.1 6.7 6.8 6.1 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal UPF0020 PF01170.18 EGD91113.2 - 1e-09 38.4 0.0 1.2e-08 34.9 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 EGD91113.2 - 3.7e-05 23.2 0.0 5.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.15 EGD91113.2 - 0.045 13.4 0.3 0.15 11.7 0.0 1.9 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase HIT PF01230.23 EGD91114.1 - 2.4e-11 44.2 0.1 9.8e-11 42.3 0.1 1.9 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EGD91114.1 - 0.0037 17.7 0.0 0.0078 16.7 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGD91114.1 - 0.038 13.8 0.1 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 Cyclin_N PF00134.23 EGD91115.1 - 6.3e-47 158.5 0.1 5.9e-45 152.1 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGD91115.1 - 1.9e-32 111.9 0.1 3.6e-32 111.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF2868 PF11067.8 EGD91115.1 - 2 7.8 7.8 0.14 11.6 2.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2868) Ribosomal_L2_C PF03947.18 EGD91117.2 - 6e-48 162.2 2.9 2.6e-34 118.1 1.9 2.6 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGD91117.2 - 5.5e-24 83.9 0.5 1.3e-23 82.8 0.5 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Fungal_trans PF04082.18 EGD91118.1 - 2.2e-18 66.2 0.1 4.9e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD91118.1 - 9.2e-10 38.5 9.6 1.9e-09 37.5 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MCCD1 PF15707.5 EGD91118.1 - 0.12 12.8 0.5 4.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial coiled-coil domain protein 1 WD40 PF00400.32 EGD91119.1 - 1.7e-27 95.1 14.9 4e-06 27.5 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD91119.1 - 1.1e-16 60.9 0.0 0.0021 18.3 0.0 5.6 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGD91119.1 - 7.7e-08 31.3 0.0 0.0011 17.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 EGD91119.1 - 0.00018 21.4 0.0 0.17 11.7 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EGD91119.1 - 0.024 14.6 3.4 3.9 7.5 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EGD91119.1 - 0.047 12.4 0.0 0.23 10.2 0.0 2.0 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nup160 PF11715.8 EGD91119.1 - 0.051 12.2 0.2 2.5 6.6 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EGD91119.1 - 0.058 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 EGD91119.1 - 0.076 12.0 0.0 5.6 5.8 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribonuc_P_40 PF08584.11 EGD91120.2 - 1.9e-72 244.0 0.0 2.3e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Dna2 PF08696.11 EGD91121.1 - 1.3e-67 227.6 0.0 3.8e-67 226.0 0.0 1.8 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.6 EGD91121.1 - 2.3e-53 180.8 0.0 4e-53 180.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGD91121.1 - 1.7e-33 116.6 0.1 2.3e-17 63.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EGD91121.1 - 2.9e-14 53.2 0.0 5.3e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGD91121.1 - 3.2e-11 43.8 0.1 7.8e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 EGD91121.1 - 3.3e-09 37.0 0.0 4.6e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 EGD91121.1 - 5.9e-08 32.9 0.0 1.6e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 EGD91121.1 - 1e-06 28.7 0.7 0.22 11.2 0.0 3.8 4 0 0 4 4 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EGD91121.1 - 0.00014 21.8 0.0 0.00035 20.5 0.0 1.7 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 EGD91121.1 - 0.00062 19.4 0.8 0.0013 18.4 0.1 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 EGD91121.1 - 0.0012 18.6 0.1 0.0022 17.6 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Csa1 PF06023.12 EGD91121.1 - 0.0068 15.8 0.0 0.064 12.6 0.0 2.2 1 1 0 1 1 1 1 CRISPR-associated exonuclease Csa1 AAA_16 PF13191.6 EGD91121.1 - 0.0073 16.7 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 EGD91121.1 - 0.02 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 EGD91121.1 - 0.025 13.8 0.3 0.092 11.9 0.3 1.8 1 1 0 1 1 1 0 PIF1-like helicase MobB PF03205.14 EGD91121.1 - 0.032 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.15 EGD91121.1 - 0.037 14.0 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CbiA PF01656.23 EGD91121.1 - 0.041 14.0 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF87 PF01935.17 EGD91121.1 - 0.052 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 EGD91121.1 - 0.058 13.8 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGD91121.1 - 0.064 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EGD91121.1 - 0.082 12.8 0.3 0.18 11.7 0.3 1.5 1 0 0 1 1 1 0 NTPase MeaB PF03308.16 EGD91121.1 - 0.19 10.7 0.1 0.39 9.7 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mito_carr PF00153.27 EGD91122.1 - 1.3e-65 217.3 0.7 4.6e-24 84.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pept_tRNA_hydro PF01195.19 EGD91122.1 - 0.042 13.8 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase HLH PF00010.26 EGD91123.1 - 1.5e-11 44.1 0.0 6.3e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain tRNA_lig_CPD PF08302.11 EGD91126.1 - 2.5e-92 308.9 0.2 4.2e-92 308.2 0.2 1.4 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 EGD91126.1 - 2.1e-84 282.8 0.4 5.4e-84 281.4 0.0 1.9 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.11 EGD91126.1 - 5.5e-50 169.7 0.1 1.3e-49 168.5 0.0 1.7 2 0 0 2 2 2 1 tRNA ligase kinase domain Tim54 PF11711.8 EGD91126.1 - 0.0031 16.3 1.4 0.0047 15.8 1.4 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 AAA_23 PF13476.6 EGD91126.1 - 0.0032 18.0 0.5 0.008 16.7 0.5 1.7 1 0 0 1 1 1 1 AAA domain DUF3217 PF11506.8 EGD91126.1 - 0.046 13.7 0.1 12 5.9 0.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3217) SUIM_assoc PF16619.5 EGD91126.1 - 0.11 12.5 8.9 0.042 13.9 2.7 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AAA_18 PF13238.6 EGD91126.1 - 0.12 12.9 2.5 0.36 11.4 0.1 3.1 3 1 0 3 3 3 0 AAA domain CotH PF08757.11 EGD91126.1 - 0.34 10.4 4.8 0.054 13.0 0.7 1.7 2 0 0 2 2 2 0 CotH kinase protein NPR3 PF03666.13 EGD91128.1 - 7.8e-154 512.9 0.0 7.8e-154 512.9 0.0 2.5 3 0 0 3 3 2 1 Nitrogen Permease regulator of amino acid transport activity 3 VPS38 PF17649.1 EGD91128.1 - 0.0042 16.0 0.3 0.021 13.7 0.0 2.2 3 0 0 3 3 3 1 Vacuolar protein sorting 38 BUD22 PF09073.10 EGD91128.1 - 0.0044 16.4 2.3 0.0044 16.4 2.3 3.2 3 0 0 3 3 3 1 BUD22 ATG22 PF11700.8 EGD91128.1 - 0.04 12.6 0.0 0.1 11.2 0.0 1.6 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like NPR2 PF06218.11 EGD91128.1 - 0.049 12.4 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Nitrogen permease regulator 2 BSP_II PF05432.11 EGD91128.1 - 0.058 13.1 49.1 1.8 8.2 5.3 3.3 2 1 0 2 2 2 0 Bone sialoprotein II (BSP-II) JAB PF01398.21 EGD91128.1 - 0.64 10.0 0.0 0.64 10.0 0.0 2.8 4 0 0 4 4 4 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Hepatitis_core PF00906.20 EGD91128.1 - 1.2 8.7 5.7 2.1 7.8 3.7 2.1 2 0 0 2 2 2 0 Hepatitis core antigen Mago-bind PF09282.10 EGD91128.1 - 1.2 9.1 6.3 3.8 7.5 6.3 1.9 1 0 0 1 1 1 0 Mago binding Myc_N PF01056.18 EGD91128.1 - 3.5 7.5 25.2 0.28 11.0 3.6 3.4 3 0 0 3 3 3 0 Myc amino-terminal region BORG_CEP PF14957.6 EGD91128.1 - 8.9 7.5 13.7 10 7.3 5.0 3.6 3 0 0 3 3 3 0 Cdc42 effector CHCH PF06747.13 EGD91129.1 - 0.00014 21.9 0.4 0.00022 21.3 0.4 1.4 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 EGD91129.1 - 0.0064 16.8 1.7 0.33 11.3 0.1 2.2 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 EGD91129.1 - 0.019 15.3 1.8 0.059 13.7 1.9 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 GFA PF04828.14 EGD91130.2 - 0.031 14.6 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Aldo_ket_red PF00248.21 EGD91132.1 - 3.6e-48 164.3 0.1 5.9e-48 163.6 0.1 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_C14 PF00656.22 EGD91133.2 - 5.7e-05 23.2 0.0 7.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 EGD91133.2 - 0.00041 20.0 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Raptor_N PF14538.6 EGD91133.2 - 0.025 14.5 2.0 0.039 13.9 0.3 2.0 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain Peptidase_S48 PF03574.15 EGD91133.2 - 0.14 12.3 0.0 0.56 10.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase family S48 PAP2 PF01569.21 EGD91135.2 - 2.9e-25 88.6 0.6 8.6e-25 87.1 0.6 1.8 1 0 0 1 1 1 1 PAP2 superfamily Mod_r PF07200.13 EGD91136.1 - 1.1e-25 90.5 0.4 1.3e-25 90.2 0.4 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein GIT_CC PF16559.5 EGD91136.1 - 0.072 13.0 0.3 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor PSK_trans_fac PF07704.11 EGD91136.1 - 0.2 12.4 1.8 0.55 11.0 1.8 1.6 1 0 0 1 1 1 0 Rv0623-like transcription factor tRNA_U5-meth_tr PF05958.11 EGD91136.1 - 0.23 10.4 0.1 0.28 10.1 0.1 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase APG6_N PF17675.1 EGD91136.1 - 0.9 10.1 4.2 0.25 11.9 0.5 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Cortex-I_coil PF09304.10 EGD91136.1 - 0.97 9.7 3.9 0.46 10.7 1.3 1.7 2 0 0 2 2 2 0 Cortexillin I, coiled coil SH3_6 PF12913.7 EGD91138.1 - 0.027 14.0 2.2 34 4.1 0.0 4.2 4 0 0 4 4 4 0 SH3 domain (SH3b1 type) AMP-binding PF00501.28 EGD91141.1 - 4.5e-72 243.0 0.0 6.7e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EGD91141.1 - 7e-72 242.0 0.0 1.3e-71 241.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EGD91141.1 - 8.3e-52 175.7 0.1 5.9e-50 169.7 0.0 2.5 2 0 0 2 2 2 1 KR domain Condensation PF00668.20 EGD91141.1 - 9e-52 176.3 0.0 1.5e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 EGD91141.1 - 5.4e-49 167.0 0.0 8.5e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EGD91141.1 - 9.8e-41 140.3 0.0 2e-40 139.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGD91141.1 - 9.5e-32 109.5 0.0 3e-31 107.9 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EGD91141.1 - 3.1e-24 85.6 0.0 5.9e-23 81.3 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 EGD91141.1 - 2.4e-20 73.1 0.0 1.7e-18 67.1 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 EGD91141.1 - 1.2e-17 64.0 0.3 7.2e-09 35.9 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EGD91141.1 - 8.7e-14 51.9 0.0 6.8e-13 49.1 0.0 2.5 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 EGD91141.1 - 2.6e-12 47.3 0.0 2.4e-11 44.2 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.21 EGD91141.1 - 2.8e-10 40.1 0.0 4.6e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 EGD91141.1 - 6.5e-10 39.1 0.0 1.5e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD91141.1 - 1.7e-09 38.2 0.0 2.9e-08 34.3 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD91141.1 - 6.2e-09 35.8 0.0 3.9e-08 33.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 EGD91141.1 - 6.7e-09 35.5 0.0 1.1e-07 31.5 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 EGD91141.1 - 3.1e-06 26.7 0.1 6.2e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 EGD91141.1 - 6.4e-06 25.7 0.0 2e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EGD91141.1 - 0.002 17.9 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase GDP_Man_Dehyd PF16363.5 EGD91141.1 - 0.0031 17.0 0.0 0.044 13.2 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Methyltransf_33 PF10017.9 EGD91141.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent UvdE PF03851.14 EGD91142.2 - 2.4e-107 358.3 0.0 3.2e-107 357.9 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE ADH_zinc_N PF00107.26 EGD91144.1 - 1.2e-10 41.4 0.0 2.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGD91144.1 - 6e-06 26.1 1.7 2e-05 24.4 1.6 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGD91144.1 - 0.0054 17.8 0.0 0.012 16.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UPF0126 PF03458.13 EGD91144.1 - 0.087 12.7 0.7 0.16 11.8 0.7 1.5 1 0 0 1 1 1 0 UPF0126 domain ADH_N_2 PF16884.5 EGD91144.1 - 0.14 12.0 0.2 2.7 7.9 0.3 2.2 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Zn_clus PF00172.18 EGD91145.1 - 2.7e-05 24.2 8.0 5.6e-05 23.2 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrome_C7 PF14522.6 EGD91145.1 - 0.16 12.0 2.8 0.29 11.2 2.8 1.4 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Pkinase PF00069.25 EGD91146.1 - 3e-63 213.7 0.0 3.6e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD91146.1 - 3.8e-29 101.8 0.0 5.8e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGD91146.1 - 0.043 12.8 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain zf-UBR PF02207.20 EGD91147.1 - 7e-14 51.7 3.8 7e-14 51.7 3.8 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.23 EGD91148.2 - 4.9e-98 326.7 0.0 8.6e-98 325.9 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGD91148.2 - 2.4e-39 134.0 0.1 4.5e-39 133.2 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EGD91148.2 - 7.5e-26 91.3 27.7 7.5e-26 91.3 27.7 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EGD91148.2 - 2.8e-24 85.3 0.3 9.5e-24 83.6 0.3 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGD91148.2 - 3.5e-12 46.8 0.2 1.1e-11 45.2 0.2 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGD91148.2 - 1.6e-07 30.9 0.2 8.9e-06 25.2 0.0 2.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGD91148.2 - 5.8e-06 26.3 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGD91148.2 - 0.00046 20.1 0.0 0.0041 17.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGD91148.2 - 0.0087 15.8 0.2 0.14 11.8 0.2 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 EGD91148.2 - 0.13 12.0 0.4 0.29 10.8 0.4 1.5 1 0 0 1 1 1 0 AAA domain NupH_GANP PF16768.5 EGD91149.2 - 0.0032 17.2 36.9 0.016 14.9 7.9 3.3 1 1 2 3 3 3 2 Nucleoporin homology of Germinal-centre associated nuclear protein VHS PF00790.19 EGD91150.2 - 1.2e-44 151.5 0.0 6.3e-44 149.2 0.0 2.1 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 EGD91150.2 - 1.3e-20 73.5 0.8 1.3e-20 73.5 0.8 3.2 4 0 0 4 4 4 1 GAT domain Alpha_adaptinC2 PF02883.20 EGD91150.2 - 4.4e-18 65.6 0.5 4.4e-18 65.6 0.5 1.8 2 0 0 2 2 2 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 EGD91150.2 - 2.2e-07 30.4 1.7 1.1e-06 28.1 0.1 2.6 2 0 0 2 2 2 1 GGA N-GAT domain Ribo_biogen_C PF04034.13 EGD91153.1 - 2.4e-50 169.5 0.1 3.3e-50 169.0 0.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EGD91153.1 - 2.3e-09 36.9 0.4 3.7e-09 36.2 0.4 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Peptidase_C37 PF05416.12 EGD91153.1 - 0.042 12.4 3.6 0.059 11.9 3.6 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase BUD22 PF09073.10 EGD91153.1 - 0.05 13.0 12.0 0.067 12.5 12.0 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EGD91153.1 - 8.4 4.5 15.0 11 4.1 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGD91153.1 - 8.6 4.5 9.4 11 4.1 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-H2C2 PF09337.10 EGD91154.1 - 1.5e-14 53.9 2.2 3.3e-14 52.8 2.2 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 EGD91154.1 - 8.8e-10 38.5 0.5 8.8e-10 38.5 0.5 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 EGD91154.1 - 0.0002 21.6 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EGD91154.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGD91154.1 - 0.18 12.5 0.0 0.37 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cpn60_TCP1 PF00118.24 EGD91155.1 - 5.5e-155 516.7 6.0 6.2e-155 516.5 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 EGD91155.1 - 0.035 14.5 0.1 13 6.3 0.0 2.7 2 0 0 2 2 2 0 Replication factor C C-terminal domain Peptidase_C14 PF00656.22 EGD91156.1 - 6.4e-61 206.5 0.0 7.9e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF1944 PF09175.10 EGD91157.1 - 0.058 13.2 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1944) Ribosomal_S26e PF01283.19 EGD91159.1 - 4.7e-51 171.7 8.2 6e-51 171.4 8.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EGD91159.1 - 0.021 14.8 0.7 0.041 13.8 0.0 1.8 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 EGD91159.1 - 0.2 11.5 1.9 0.26 11.1 1.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) CBS PF00571.28 EGD91160.2 - 4.2e-36 123.2 5.5 4.1e-09 36.7 0.0 5.7 6 0 0 6 6 6 4 CBS domain PB1 PF00564.24 EGD91160.2 - 6.8e-11 42.0 0.1 3.2e-10 39.8 0.0 2.3 2 1 0 2 2 2 1 PB1 domain Importin_rep_4 PF18808.1 EGD91161.1 - 9.2e-33 112.4 2.6 3.5e-32 110.6 1.0 3.0 2 0 0 2 2 2 1 Importin repeat Importin_rep_5 PF18816.1 EGD91161.1 - 8.7e-23 80.4 0.3 2.7e-22 78.8 0.3 2.0 1 0 0 1 1 1 1 Importin repeat HEAT_2 PF13646.6 EGD91161.1 - 2.1e-20 72.9 3.2 0.00011 22.6 0.0 7.4 5 2 2 8 8 7 5 HEAT repeats HEAT_EZ PF13513.6 EGD91161.1 - 1.5e-19 70.1 12.4 1.3e-08 35.2 0.3 8.6 9 1 1 10 10 9 2 HEAT-like repeat HEAT PF02985.22 EGD91161.1 - 2.6e-18 64.5 6.1 0.0072 16.5 0.0 11.0 11 0 0 11 11 9 4 HEAT repeat Importin_rep_6 PF18829.1 EGD91161.1 - 4.8e-14 52.4 0.8 3e-13 49.8 0.2 2.7 2 0 0 2 2 2 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 EGD91161.1 - 1.2e-09 38.7 0.0 0.094 13.3 0.0 6.0 3 2 2 6 6 6 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 EGD91161.1 - 1.8e-09 37.2 1.0 0.00013 21.2 0.1 5.0 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 EGD91161.1 - 9.2e-08 32.2 2.0 0.22 11.4 0.0 6.5 6 3 2 9 9 9 2 Domain of unknown function (DUF3385) Cnd1 PF12717.7 EGD91161.1 - 4.5e-07 30.1 0.0 0.027 14.5 0.0 4.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 EGD91161.1 - 2e-06 27.7 0.9 0.0011 18.8 0.1 4.9 5 2 0 5 5 5 1 rRNA processing/ribosome biogenesis DRIM PF07539.12 EGD91161.1 - 2.1e-06 26.4 0.9 0.032 12.6 0.1 4.3 3 2 0 4 4 4 2 Down-regulated in metastasis Arm PF00514.23 EGD91161.1 - 1.1e-05 25.3 0.6 1.3 9.1 0.1 5.0 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EGD91161.1 - 2.5e-05 24.0 0.0 0.21 11.1 0.0 5.1 5 1 0 5 5 4 1 CLASP N terminal RTP1_C1 PF10363.9 EGD91161.1 - 4.6e-05 23.6 0.2 0.21 11.8 0.1 4.8 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 EGD91161.1 - 0.00059 18.5 1.3 0.013 14.0 0.1 3.5 3 1 2 5 5 5 1 Adaptin N terminal region IBN_N PF03810.19 EGD91161.1 - 0.00063 19.6 1.1 0.007 16.3 0.0 3.4 4 0 0 4 4 3 1 Importin-beta N-terminal domain V-ATPase_H_N PF03224.14 EGD91161.1 - 0.021 14.1 2.8 0.13 11.5 0.0 3.3 4 0 0 4 4 4 0 V-ATPase subunit H Cnd3 PF12719.7 EGD91161.1 - 0.036 13.3 1.1 3.8 6.6 0.0 4.1 3 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain TFCD_C PF12612.8 EGD91161.1 - 0.059 13.2 1.0 19 5.0 0.0 3.9 4 0 0 4 4 4 0 Tubulin folding cofactor D C terminal DUF4042 PF13251.6 EGD91161.1 - 0.13 11.9 5.6 16 5.2 0.0 5.1 7 0 0 7 7 6 0 Domain of unknown function (DUF4042) Aconitase PF00330.20 EGD91162.2 - 8.4e-139 463.5 0.0 1.1e-138 463.1 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGD91162.2 - 1.8e-40 138.3 0.0 2.9e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2408 PF10303.9 EGD91163.1 - 1.3e-50 171.4 0.1 7.6e-29 101.0 0.0 5.2 4 2 1 5 5 5 4 Protein of unknown function (DUF2408) CARD PF00619.21 EGD91163.1 - 0.039 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Caspase recruitment domain Snapin_Pallidin PF14712.6 EGD91163.1 - 0.14 12.6 1.0 5.7 7.4 0.1 3.3 3 0 0 3 3 3 0 Snapin/Pallidin Baculo_PEP_C PF04513.12 EGD91163.1 - 0.18 11.9 0.9 2 8.4 0.1 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_60s PF00428.19 EGD91164.2 - 2.4e-25 88.9 7.3 3.4e-25 88.5 7.3 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Glyco_transf_21 PF13506.6 EGD91164.2 - 0.068 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 PQ-loop PF04193.14 EGD91165.1 - 8.1e-39 131.2 10.6 8.9e-20 70.2 0.0 2.8 3 0 0 3 3 3 2 PQ loop repeat DUF3021 PF11457.8 EGD91165.1 - 1.9 8.8 9.4 0.84 10.0 3.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) Tcf25 PF04910.14 EGD91166.1 - 2.7e-74 250.3 0.1 3.7e-74 249.9 0.1 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Stm1_N PF09598.10 EGD91166.1 - 0.013 16.3 5.4 0.05 14.5 5.4 2.0 1 0 0 1 1 1 0 Stm1 DUF3381 PF11861.8 EGD91166.1 - 2.8 7.7 7.8 4.8 7.0 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PP2C PF00481.21 EGD91167.1 - 3.2e-42 144.9 0.0 5.2e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGD91167.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Baseplate_J PF04865.14 EGD91167.1 - 0.022 13.9 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Baseplate J-like protein SpoIIE PF07228.12 EGD91167.1 - 0.13 12.2 0.0 2.8 7.8 0.0 2.5 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) PPDFL PF15060.6 EGD91167.1 - 1.1 9.9 6.1 11 6.6 0.0 2.9 2 1 0 2 2 2 0 Differentiation and proliferation regulator 60KD_IMP PF02096.20 EGD91168.2 - 1.7e-16 60.6 0.8 1.1e-15 57.9 0.8 1.9 1 1 0 1 1 1 1 60Kd inner membrane protein ALG11_N PF15924.5 EGD91169.1 - 2.4e-82 276.0 0.0 3.3e-82 275.6 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EGD91169.1 - 2.5e-19 69.4 0.0 6.1e-19 68.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGD91169.1 - 9.4e-08 32.6 0.0 8.7e-07 29.4 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 HemY_N PF07219.13 EGD91169.1 - 0.016 15.4 0.1 0.084 13.1 0.1 2.3 1 0 0 1 1 1 0 HemY protein N-terminus Glyco_transf_4 PF13439.6 EGD91169.1 - 0.04 13.9 0.1 0.083 12.9 0.1 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Methyltransf_23 PF13489.6 EGD91173.2 - 5.2e-17 62.2 0.0 7.6e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD91173.2 - 1.3e-08 35.4 0.0 4.5e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD91173.2 - 2.3e-05 24.9 0.0 6.5e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD91173.2 - 4.7e-05 23.2 0.0 0.00012 21.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGD91173.2 - 0.0002 20.9 0.0 0.00047 19.7 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 EGD91173.2 - 0.00036 21.2 0.0 0.0012 19.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGD91173.2 - 0.00095 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EGD91173.2 - 0.0013 18.9 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 EGD91173.2 - 0.006 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EGD91173.2 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 EGD91173.2 - 0.021 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 EGD91173.2 - 0.07 12.4 0.0 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGD91173.2 - 0.11 11.8 0.0 0.57 9.5 0.0 2.0 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family WD40 PF00400.32 EGD91174.1 - 7.2e-16 58.3 10.5 2.4e-06 28.2 0.5 5.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD91174.1 - 3.4e-11 43.3 1.3 0.006 16.9 0.0 4.3 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGD91174.1 - 8.3e-05 22.6 0.1 0.78 9.6 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EGD91174.1 - 0.1 11.1 0.0 0.21 10.1 0.0 1.6 1 0 0 1 1 1 0 Cytochrome D1 heme domain RNA_pol_Rpb1_5 PF04998.17 EGD91175.2 - 3.8e-105 351.1 0.0 6.3e-105 350.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGD91175.2 - 6.9e-75 250.8 0.0 1.7e-74 249.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EGD91175.2 - 2e-65 220.2 1.4 3.9e-65 219.3 1.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_1 PF04997.12 EGD91175.2 - 9.5e-57 192.7 0.1 2e-56 191.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 EGD91175.2 - 2.4e-47 160.8 0.0 6e-47 159.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EGD91175.2 - 1.9e-44 150.9 7.7 3.2e-44 150.2 5.9 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EGD91175.2 - 6.5e-38 129.0 0.2 1.4e-37 127.9 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EGD91175.2 - 1.3e-13 50.5 209.2 0.0071 16.7 8.7 14.8 12 2 1 14 14 14 10 RNA polymerase Rpb1 C-terminal repeat DUF4407 PF14362.6 EGD91176.1 - 7.7 5.8 13.6 11 5.3 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Thg1C PF14413.6 EGD91177.2 - 2.5e-31 108.4 1.8 7e-17 61.7 0.3 2.2 1 1 1 2 2 2 2 Thg1 C terminal domain fn3 PF00041.21 EGD91178.1 - 0.00071 19.9 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain DUF4407 PF14362.6 EGD91178.1 - 0.3 10.4 26.2 0.14 11.5 23.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Snapin_Pallidin PF14712.6 EGD91178.1 - 0.4 11.1 23.5 0.81 10.1 1.7 3.2 2 1 0 2 2 2 0 Snapin/Pallidin APG6_N PF17675.1 EGD91178.1 - 0.65 10.5 47.2 0.16 12.5 3.5 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region LNS2 PF08235.13 EGD91179.2 - 2e-95 318.5 0.0 2.8e-95 318.1 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EGD91179.2 - 1e-23 83.2 0.0 2.3e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EGD91179.2 - 0.013 15.1 0.0 0.13 11.8 0.0 2.4 3 0 0 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) TFIID-31kDa PF02291.15 EGD91180.1 - 5.6e-45 152.4 0.0 7.4e-45 152.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit LRR19-TM PF15176.6 EGD91180.1 - 1.7 8.7 3.5 2.9 7.9 3.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Cmc1 PF08583.10 EGD91181.1 - 4e-12 46.0 3.6 1e-11 44.6 3.6 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Metal_resist PF13801.6 EGD91181.1 - 0.42 10.8 8.7 0.47 10.6 5.0 2.0 2 0 0 2 2 2 0 Heavy-metal resistance Utp11 PF03998.13 EGD91182.1 - 7.2e-57 193.1 28.5 8.3e-57 192.9 28.5 1.0 1 0 0 1 1 1 1 Utp11 protein AAA PF00004.29 EGD91182.1 - 0.35 11.3 2.5 3.3 8.1 2.4 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GCIP PF13324.6 EGD91182.1 - 0.93 9.0 7.4 1.3 8.6 7.4 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Histidinol_dh PF00815.20 EGD91183.2 - 2.1e-152 507.9 6.7 1.3e-136 455.9 4.4 2.2 2 0 0 2 2 2 2 Histidinol dehydrogenase PRA-CH PF01502.18 EGD91183.2 - 6.6e-24 83.5 0.1 1.4e-23 82.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EGD91183.2 - 2.8e-14 53.3 0.6 1.4e-13 51.1 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 EGD91183.2 - 0.8 9.9 3.4 0.34 11.1 0.3 2.0 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Glyco_hydro_47 PF01532.20 EGD91185.2 - 2.8e-137 458.4 0.0 7.3e-109 364.7 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 TFIIA PF03153.13 EGD91186.2 - 0.46 10.4 7.7 0.68 9.9 7.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acetyltransf_3 PF13302.7 EGD91187.1 - 3.6e-18 66.6 0.0 6.4e-18 65.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGD91187.1 - 7.9e-09 35.8 0.0 1.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGD91187.1 - 0.0009 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EGD91187.1 - 0.052 13.5 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 EGD91188.1 - 1e-42 146.5 46.5 1.3e-42 146.1 46.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD91188.1 - 1.1e-22 80.3 43.5 6.5e-22 77.8 43.5 1.8 1 1 0 1 1 1 1 Amino acid permease YlaH PF14036.6 EGD91188.1 - 0.0001 22.6 1.5 0.00053 20.3 1.5 2.2 1 0 0 1 1 1 1 YlaH-like protein CBM_19 PF03427.13 EGD91188.1 - 0.082 12.9 0.6 0.24 11.4 0.6 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Acetyltransf_7 PF13508.7 EGD91190.1 - 2.6e-09 37.4 0.0 4.3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGD91190.1 - 1.7e-08 34.4 0.0 2.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGD91190.1 - 1.5e-07 31.7 0.0 3e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGD91190.1 - 5.1e-05 23.2 0.0 9.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGD91190.1 - 0.016 15.2 0.3 1.8 8.6 0.0 2.5 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain CDC45 PF02724.14 EGD91191.1 - 1.8e-238 793.0 0.0 7.8e-238 790.9 0.0 2.5 1 1 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 EGD91191.1 - 0.6 9.4 26.7 0.29 10.4 10.1 2.1 2 0 0 2 2 2 0 BUD22 CSRNP_N PF16019.5 EGD91191.1 - 2.2 8.2 5.6 4.7 7.1 5.6 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus FAM60A PF15396.6 EGD91191.1 - 2.8 7.9 6.0 0.28 11.2 1.0 1.7 2 0 0 2 2 2 0 Protein Family FAM60A Med5 PF08689.10 EGD91191.1 - 3.7 5.2 4.5 5.2 4.8 4.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 DUF572 PF04502.13 EGD91191.1 - 9.5 5.7 15.4 1.9 8.0 8.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF3043 PF11241.8 EGD91191.1 - 9.6 6.2 14.6 19 5.2 14.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Peptidase_C13 PF01650.18 EGD91192.1 - 2e-41 142.2 0.0 3e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family F-box-like PF12937.7 EGD91193.2 - 3.3e-07 30.1 0.2 6.4e-07 29.2 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD91193.2 - 2.1e-06 27.5 0.4 5.9e-06 26.0 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGD91193.2 - 0.0027 17.6 0.1 0.006 16.4 0.1 1.6 1 0 0 1 1 1 1 F-box Ccdc124 PF06244.12 EGD91194.1 - 5.6e-28 98.1 26.2 5.6e-28 98.1 26.2 2.4 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 WD40 PF00400.32 EGD91195.1 - 1.1e-15 57.7 14.0 0.0053 17.6 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF1518 PF07469.12 EGD91195.1 - 0.39 11.2 3.1 2 8.9 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) Abhydrolase_6 PF12697.7 EGD91196.1 - 9.5e-15 55.8 4.9 4.7e-14 53.5 4.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGD91196.1 - 0.0071 16.0 0.0 0.014 15.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 EGD91197.1 - 1.9e-35 122.4 11.9 9.6e-34 116.8 12.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD91197.1 - 7.4e-10 38.3 1.7 1.7e-09 37.1 1.7 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGD91197.1 - 0.0041 16.0 2.8 0.0041 16.0 2.8 2.4 2 0 0 2 2 2 1 MFS_1 like family GTP1_OBG PF01018.22 EGD91200.1 - 4.9e-37 126.9 2.3 4.1e-27 94.7 3.3 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EGD91200.1 - 3.1e-22 78.8 0.0 5.7e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGD91200.1 - 2.6e-08 33.5 0.0 5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 EGD91200.1 - 0.02 13.9 0.1 0.48 9.3 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EGD91200.1 - 0.067 13.7 1.5 0.15 12.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter UQ_con PF00179.26 EGD91201.1 - 5.1e-10 39.1 0.0 8.6e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGD91201.1 - 0.16 12.2 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 RWD domain 2OG-FeII_Oxy_2 PF13532.6 EGD91203.1 - 4.8e-36 124.8 0.1 6.8e-36 124.3 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.16 EGD91203.1 - 0.00014 21.5 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain zf-GRF PF06839.12 EGD91203.1 - 0.0004 20.4 7.9 0.0004 20.4 7.9 1.9 2 0 0 2 2 2 1 GRF zinc finger Cupin_8 PF13621.6 EGD91204.1 - 3.9e-33 115.2 0.0 7.8e-33 114.3 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGD91204.1 - 1.6e-06 27.9 0.1 0.0011 18.5 0.0 2.5 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.22 EGD91204.1 - 0.027 14.9 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase Homeobox_KN PF05920.11 EGD91206.1 - 1.3e-15 57.0 1.0 2.8e-15 55.9 0.2 2.1 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 EGD91206.1 - 0.00011 22.2 0.0 0.00048 20.1 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 EGD91206.1 - 0.00026 20.8 0.1 0.00065 19.5 0.1 1.8 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 EGD91206.1 - 0.00075 20.1 1.5 0.00075 20.1 1.5 5.1 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGD91206.1 - 0.0039 17.6 22.4 0.072 13.6 1.6 4.8 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EGD91206.1 - 0.79 10.4 5.8 1 10.0 0.3 3.0 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 EGD91206.1 - 1.2 9.7 9.3 6.8 7.3 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double domain Fungal_trans PF04082.18 EGD91208.1 - 3.4e-25 88.6 0.0 1e-24 87.0 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD91208.1 - 3.8e-08 33.3 13.3 6.3e-08 32.6 13.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adenylsucc_synt PF00709.21 EGD91211.2 - 9.1e-87 291.7 0.0 1e-86 291.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ank_2 PF12796.7 EGD91212.1 - 1.6e-06 28.6 0.8 0.076 13.6 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD91212.1 - 0.0041 17.6 1.5 0.72 10.5 0.0 4.3 4 2 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD91212.1 - 0.0083 16.6 2.9 5.7 7.9 0.1 5.1 6 0 0 6 6 6 1 Ankyrin repeat Mating_C PF12737.7 EGD91212.1 - 0.077 12.2 0.2 0.11 11.7 0.2 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Adenylsucc_synt PF00709.21 EGD91213.1 - 1.5e-170 567.7 0.0 1.7e-170 567.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase KHA PF11834.8 EGD91213.1 - 0.077 13.1 0.0 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel Ank_2 PF12796.7 EGD91214.1 - 2.5e-29 101.7 22.1 7e-07 29.8 0.0 12.6 8 4 5 13 13 13 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD91214.1 - 1.7e-22 79.5 19.6 0.003 18.1 0.0 14.4 12 4 3 15 15 15 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGD91214.1 - 1.9e-14 53.5 0.9 0.01 16.2 0.0 9.8 9 1 1 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD91214.1 - 9.9e-14 50.1 14.1 10 7.1 0.0 16.2 21 0 0 21 21 21 3 Ankyrin repeat Ank PF00023.30 EGD91214.1 - 2.6e-08 33.9 32.6 1.2 9.7 0.1 14.9 16 3 0 16 16 16 3 Ankyrin repeat VLPT PF07122.11 EGD91214.1 - 0.52 10.1 3.2 4.1 7.2 0.1 2.9 2 0 0 2 2 2 0 Variable length PCR target protein (VLPT) DEAD PF00270.29 EGD91215.1 - 3.7e-43 147.3 0.0 5.5e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD91215.1 - 4.6e-19 68.8 0.3 2.7e-18 66.3 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD91215.1 - 8.1e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Aldolase_II PF00596.21 EGD91216.1 - 7.3e-46 156.5 0.1 9.2e-46 156.1 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PLAC8 PF04749.17 EGD91217.1 - 7.9e-17 62.1 11.1 9.6e-17 61.8 11.1 1.1 1 0 0 1 1 1 1 PLAC8 family Abhydrolase_3 PF07859.13 EGD91219.2 - 1.8e-25 90.0 0.3 2.4e-25 89.7 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EGD91219.2 - 0.026 14.7 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Methyltr_RsmB-F PF01189.17 EGD91220.1 - 2e-31 109.2 0.0 1.1e-23 83.9 0.0 3.2 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 EGD91220.1 - 0.2 11.0 0.0 0.86 8.9 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family ECF_trnsprt PF12822.7 EGD91221.2 - 0.025 14.7 0.0 0.03 14.4 0.0 1.1 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Syndecan PF01034.20 EGD91221.2 - 0.44 10.5 2.0 0.44 10.5 0.2 1.8 2 0 0 2 2 2 0 Syndecan domain CYSTM PF12734.7 EGD91222.1 - 1.9e-07 31.3 4.8 1.9e-07 31.3 4.8 3.9 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance DUF2076 PF09849.9 EGD91222.1 - 0.64 10.0 14.1 0.91 9.5 14.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 EGD91222.1 - 0.78 10.4 9.6 0.95 10.1 9.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2968 PF11180.8 EGD91223.2 - 0.0004 20.1 9.4 0.0004 20.1 9.4 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2968) Spectrin PF00435.21 EGD91223.2 - 0.012 16.1 9.2 0.012 16.1 9.2 2.8 2 1 0 2 2 2 0 Spectrin repeat Fib_alpha PF08702.10 EGD91223.2 - 0.016 15.4 3.5 0.016 15.4 3.5 3.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 EGD91223.2 - 0.13 12.8 40.8 0.037 14.5 18.4 3.7 1 1 1 3 3 3 0 Apg6 coiled-coil region DUF4363 PF14276.6 EGD91223.2 - 0.17 12.0 12.9 0.023 14.8 4.6 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4363) CENP-F_leu_zip PF10473.9 EGD91223.2 - 0.22 11.5 31.8 1 9.4 17.6 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 EGD91223.2 - 0.88 9.6 13.0 1.9 8.5 3.4 3.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.9 EGD91223.2 - 1.1 9.6 20.6 0.5 10.7 0.2 4.7 1 1 3 5 5 5 0 Uncharacterized conserved protein Osmo_CC PF08946.10 EGD91223.2 - 1.1 9.5 11.4 1.6 9.1 1.5 3.9 3 1 0 3 3 3 0 Osmosensory transporter coiled coil Occludin_ELL PF07303.13 EGD91223.2 - 4 8.2 30.5 2.5 8.9 2.1 4.1 2 1 2 4 4 3 0 Occludin homology domain DUF1664 PF07889.12 EGD91223.2 - 5.6 7.0 17.8 2.5 8.1 4.9 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EGD91223.2 - 8.2 6.9 14.3 44 4.6 0.0 5.7 2 1 4 6 6 6 0 Flagella accessory protein C (FlaC) Sec34 PF04136.15 EGD91223.2 - 8.6 6.2 16.2 0.26 11.2 3.0 3.4 1 1 3 4 4 4 0 Sec34-like family RNA_pol_Rpb5_C PF01191.19 EGD91224.1 - 9.8e-34 115.1 0.1 1.7e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EGD91224.1 - 3.8e-26 91.5 0.0 6e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EGD91224.1 - 0.00035 20.6 0.0 0.00091 19.2 0.0 1.6 2 0 0 2 2 2 1 Restriction endonuclease AMP-binding PF00501.28 EGD91230.1 - 1.1e-43 149.4 0.0 1.7e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD91230.1 - 0.0017 19.3 0.0 0.0036 18.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGD91230.1 - 0.016 15.1 0.0 0.068 13.1 0.0 2.1 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus zf-C2H2_jaz PF12171.8 EGD91231.1 - 2.4e-08 34.1 0.4 4e-08 33.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGD91231.1 - 9.3e-06 25.9 0.5 9.3e-06 25.9 0.5 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EGD91231.1 - 0.00082 19.7 0.4 0.0016 18.8 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type Tam41_Mmp37 PF09139.11 EGD91233.1 - 1.8e-131 438.4 0.0 2.1e-131 438.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Aminotran_1_2 PF00155.21 EGD91235.1 - 7e-63 213.0 0.0 8.3e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGD91235.1 - 0.024 13.2 0.1 0.051 12.1 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGD91235.1 - 0.065 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V TFIID-18kDa PF02269.16 EGD91236.1 - 2e-30 104.6 0.4 2.3e-29 101.2 0.4 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TP_methylase PF00590.20 EGD91237.2 - 1.8e-19 70.6 0.4 1.6e-10 41.3 0.1 2.3 2 0 0 2 2 2 2 Tetrapyrrole (Corrin/Porphyrin) Methylases Orbi_NS1 PF01718.16 EGD91238.1 - 0.031 12.7 0.0 0.04 12.4 0.0 1.1 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Clat_adaptor_s PF01217.20 EGD91239.1 - 2e-54 183.4 2.3 2.4e-54 183.1 2.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AMP-binding PF00501.28 EGD91240.2 - 3.5e-20 72.0 0.0 4.3e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD91240.2 - 1.2e-05 26.2 0.0 2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_S28 PF05577.12 EGD91243.1 - 3.1e-56 191.0 0.8 5.3e-56 190.2 0.8 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Ist1 PF03398.14 EGD91245.1 - 3.8e-27 95.2 0.6 7.7e-15 55.2 1.7 2.1 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway zf-CCCH PF00642.24 EGD91246.2 - 0.00076 19.3 1.2 0.0016 18.3 1.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EGD91246.2 - 0.0076 16.5 0.2 0.016 15.4 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger containing family Torus PF16131.5 EGD91246.2 - 0.047 14.4 1.6 0.061 14.0 1.4 1.6 1 1 0 1 1 1 0 Torus domain zf_CCCH_4 PF18345.1 EGD91246.2 - 0.39 10.9 8.5 1.2 9.3 8.5 1.9 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 EGD91246.2 - 2.4 8.7 8.5 0.19 12.3 2.6 2.2 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger SUN PF03856.13 EGD91247.1 - 3.8e-72 242.7 11.6 5.4e-72 242.2 11.6 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) SPX PF03105.19 EGD91247.1 - 0.33 10.8 10.4 0.47 10.3 10.4 1.3 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 EGD91247.1 - 2 7.5 18.1 2.8 7.0 18.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 EGD91247.1 - 4.7 5.9 11.3 6.8 5.4 11.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain LCM PF04072.14 EGD91248.1 - 1.6e-22 80.3 0.0 3.8e-22 79.1 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DUF647 PF04884.14 EGD91248.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis zf-RING_2 PF13639.6 EGD91249.2 - 1.1e-07 32.1 11.7 2.8e-07 30.7 11.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EGD91249.2 - 0.00017 21.6 4.1 0.00039 20.4 4.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGD91249.2 - 0.00024 21.3 10.5 0.00094 19.4 10.8 1.9 1 1 1 2 2 2 1 RING-H2 zinc finger domain FANCL_C PF11793.8 EGD91249.2 - 0.001 19.2 6.8 0.0021 18.2 6.8 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 EGD91249.2 - 0.0027 17.5 11.1 0.0089 15.9 11.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGD91249.2 - 0.004 17.0 13.0 0.0085 15.9 13.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGD91249.2 - 0.015 14.9 6.7 0.033 13.8 6.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DICT PF10069.9 EGD91249.2 - 0.073 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system DUF2913 PF11140.8 EGD91249.2 - 0.097 12.4 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2913) zf-RING-like PF08746.11 EGD91249.2 - 0.17 12.2 10.1 0.41 11.0 10.1 1.7 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.22 EGD91249.2 - 0.83 9.6 8.7 0.31 11.0 5.6 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.7 EGD91249.2 - 1.3 9.2 10.1 2.6 8.2 10.1 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 EGD91249.2 - 3.6 7.5 5.5 9.4 6.1 5.5 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 EGD91249.2 - 5.5 6.9 7.8 14 5.6 7.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DEAD_2 PF06733.15 EGD91250.1 - 3.7e-56 189.5 0.1 7.9e-56 188.4 0.1 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EGD91250.1 - 8.2e-48 162.6 1.8 1.4e-42 145.6 0.6 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EGD91250.1 - 5.3e-44 150.4 0.0 1.5e-43 148.9 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 EGD91250.1 - 5.8e-06 26.4 0.0 0.00094 19.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGD91250.1 - 0.00039 20.2 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.23 EGD91250.1 - 0.0073 15.1 0.1 0.2 10.4 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 EGD91250.1 - 0.061 13.6 2.1 12 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EGD91250.1 - 0.15 12.4 0.0 0.61 10.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGD91250.1 - 1.5 8.6 4.0 0.88 9.3 0.2 2.3 2 1 0 2 2 2 0 AAA domain RNA_pol_Rpb1_5 PF04998.17 EGD91251.2 - 3e-87 292.4 0.1 4.9e-87 291.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGD91251.2 - 5.4e-67 225.2 0.1 1.3e-66 223.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGD91251.2 - 5.6e-33 114.1 0.0 2.6e-31 108.7 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGD91251.2 - 1.6e-17 63.4 0.0 6.2e-17 61.5 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 EGD91251.2 - 8.1e-07 28.7 0.9 6.5e-06 25.7 0.8 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 PRP3 PF08572.10 EGD91252.1 - 2.3e-74 249.9 3.9 3.9e-74 249.2 3.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EGD91252.1 - 3e-48 163.6 0.6 3e-48 163.6 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Zn_clus PF00172.18 EGD91253.1 - 1.5e-06 28.2 10.5 2.3e-06 27.6 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGD91253.1 - 7.3e-05 21.9 0.1 0.00019 20.5 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain ERCC4 PF02732.15 EGD91254.1 - 3e-25 89.2 0.0 5e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 EGD91254.1 - 0.015 15.7 0.2 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain E1-E2_ATPase PF00122.20 EGD91255.1 - 1.7e-49 167.8 0.0 7.1e-49 165.8 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 EGD91255.1 - 2e-38 130.6 3.6 3.5e-10 40.2 0.1 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 EGD91255.1 - 3.8e-35 122.1 0.1 6.6e-35 121.3 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGD91255.1 - 4.4e-05 23.3 1.2 0.00093 19.0 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGD91255.1 - 0.0024 18.3 0.0 0.0056 17.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TFIIB PF00382.19 EGD91256.1 - 4.9e-31 106.6 0.4 4.1e-17 62.0 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EGD91256.1 - 5.6e-25 87.6 2.7 1e-24 86.8 0.0 2.9 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EGD91256.1 - 0.00013 21.4 2.7 0.00028 20.3 2.7 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EGD91256.1 - 0.018 14.8 0.1 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Cyclin, N-terminal domain RNase_H PF00075.24 EGD91260.2 - 1.3e-19 70.8 0.0 1.7e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EGD91260.2 - 1.2e-05 25.1 0.2 0.001 18.9 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like Amino_oxidase PF01593.24 EGD91263.1 - 1.2e-08 34.7 0.0 2.4e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGD91263.1 - 1.1e-07 32.0 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGD91263.1 - 0.0016 17.7 0.1 0.021 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGD91263.1 - 0.009 15.3 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGD91263.1 - 0.015 14.6 0.1 0.033 13.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EGD91263.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGD91263.1 - 0.046 13.0 0.1 0.072 12.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 EGD91263.1 - 0.075 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 EGD91263.1 - 0.091 11.8 0.3 0.27 10.3 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 EGD91263.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thyroglob_assoc PF16597.5 EGD91265.1 - 0.1 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Thyroglobulin_1 repeat associated disordered domain DUF4360 PF14273.6 EGD91268.2 - 1e-27 97.1 0.9 1.3e-27 96.8 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) BTB PF00651.31 EGD91269.2 - 0.085 13.1 0.1 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain Pneumovirus_M2 PF06436.11 EGD91269.2 - 0.14 11.6 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) MerR-DNA-bind PF09278.11 EGD91269.2 - 0.24 11.9 0.6 13 6.5 0.1 2.6 2 0 0 2 2 2 0 MerR, DNA binding ASFV_J13L PF05568.11 EGD91269.2 - 1.6 8.5 5.2 0.49 10.1 1.9 1.7 2 0 0 2 2 2 0 African swine fever virus J13L protein Sugar_tr PF00083.24 EGD91270.2 - 1.2e-107 360.6 24.0 1.5e-107 360.3 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGD91270.2 - 6e-17 61.6 39.9 5.6e-13 48.5 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGD91270.2 - 2.1e-05 23.0 1.0 2.1e-05 23.0 1.0 2.5 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF3464 PF11947.8 EGD91270.2 - 0.014 15.1 2.9 0.04 13.7 2.9 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 zf-CCHC PF00098.23 EGD91272.2 - 6.1e-54 177.8 103.9 1.4e-07 31.3 2.5 11.3 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_2 PF13696.6 EGD91272.2 - 1.3e-11 44.1 89.6 0.00062 19.5 0.5 11.4 11 0 0 11 11 11 7 Zinc knuckle zf-CCHC_3 PF13917.6 EGD91272.2 - 1.9e-08 34.1 77.6 0.052 13.5 0.8 11.1 2 2 9 11 11 11 8 Zinc knuckle zf-CCHC_4 PF14392.6 EGD91272.2 - 8.5e-08 31.8 68.9 0.25 11.1 0.4 11.2 11 0 0 11 11 11 7 Zinc knuckle zf-CCHC_6 PF15288.6 EGD91272.2 - 0.0075 16.1 2.9 0.0075 16.1 2.9 10.5 8 2 2 10 10 10 4 Zinc knuckle zf-CCCH_8 PF18633.1 EGD91272.2 - 0.023 14.8 2.4 0.023 14.8 2.4 2.4 2 0 0 2 2 2 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 zf-C2H2_10 PF16588.5 EGD91272.2 - 0.029 14.1 2.8 0.029 14.1 2.8 9.4 10 0 0 10 10 10 0 C2H2 zinc-finger DUF846 PF05832.12 EGD91273.1 - 3.3e-48 163.2 10.1 3.9e-48 163.0 10.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Acyl-CoA_dh_1 PF00441.24 EGD91274.1 - 7.1e-31 107.5 0.1 9.7e-31 107.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGD91274.1 - 4.1e-26 91.9 0.0 8.5e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGD91274.1 - 3.2e-22 78.5 0.0 5.6e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGD91274.1 - 0.0029 17.9 0.0 0.0042 17.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 EGD91275.1 - 4.2e-47 160.6 0.0 5.5e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGD91275.1 - 1.5e-24 87.1 0.1 4.1e-22 79.1 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HpcH_HpaI PF03328.14 EGD91277.1 - 2.9e-43 147.6 0.1 2.6e-42 144.4 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EGD91277.1 - 6.7e-15 55.1 0.1 3.3e-07 29.8 0.0 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 EGD91277.1 - 0.1 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain DUF1771 PF08590.10 EGD91278.2 - 7.9e-14 51.8 5.0 7.9e-14 51.8 5.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EGD91278.2 - 2.9e-10 40.3 0.0 1e-09 38.6 0.0 2.0 1 0 0 1 1 1 1 Smr domain zf_CCCH_4 PF18345.1 EGD91278.2 - 6.5e-08 32.4 10.7 7.9e-07 28.9 0.8 3.2 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 EGD91278.2 - 6.5e-07 29.1 2.3 0.0059 16.5 0.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGD91278.2 - 5.6e-06 26.0 11.1 0.00012 21.8 0.8 3.0 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EGD91278.2 - 0.00081 19.8 6.1 0.13 12.8 0.9 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EGD91278.2 - 0.0055 16.9 8.4 0.31 11.3 0.1 3.0 1 1 1 2 2 2 2 Zinc-finger containing family CUE PF02845.16 EGD91278.2 - 0.081 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 CUE domain Plasmodium_Vir PF05795.11 EGD91278.2 - 10 5.5 7.7 1.7 7.9 2.0 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Glyco_transf_90 PF05686.12 EGD91279.2 - 1.3e-15 57.2 1.8 1e-09 37.8 1.3 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 Oxidored_molyb PF00174.19 EGD91280.2 - 5e-51 172.7 0.0 6.5e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGD91280.2 - 4.2e-13 49.5 0.0 7.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain CAP59_mtransfer PF11735.8 EGD91281.2 - 5e-84 281.8 0.0 6.6e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 AICARFT_IMPCHas PF01808.18 EGD91282.2 - 1.1e-89 300.8 0.0 2.1e-89 299.9 0.0 1.5 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EGD91282.2 - 6.3e-08 32.7 0.0 1.2e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DUF346 PF03984.13 EGD91283.1 - 3.5e-59 196.3 63.0 3.9e-10 39.3 0.4 7.2 7 0 0 7 7 7 7 Repeat of unknown function (DUF346) Ntox14 PF15522.6 EGD91283.1 - 1.9e-05 24.2 0.0 22 4.4 0.0 6.2 7 0 0 7 7 7 1 Novel toxin 14 DUF2510 PF10708.9 EGD91283.1 - 0.014 15.1 47.3 0.33 10.8 2.9 6.4 6 0 0 6 6 6 0 Protein of unknown function (DUF2510) DUF1724 PF08350.10 EGD91283.1 - 0.017 15.3 7.5 4 7.6 0.0 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF1724) Fungal_lectin PF07938.12 EGD91283.1 - 0.048 13.0 15.8 0.18 11.2 0.2 4.5 1 1 1 3 3 3 0 Fungal fucose-specific lectin SNARE_assoc PF09335.11 EGD91284.1 - 1.1e-11 45.3 4.9 1.1e-11 45.3 4.9 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein Amino_oxidase PF01593.24 EGD91285.2 - 7.4e-84 282.6 0.1 5.3e-74 250.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 EGD91285.2 - 6.9e-14 52.0 0.1 2.3e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 EGD91285.2 - 8.1e-07 29.2 0.1 1.7e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 EGD91285.2 - 4.2e-05 23.9 5.3 4.4e-05 23.8 2.6 2.4 2 1 0 2 2 2 1 HMG (high mobility group) box Pyr_redox_2 PF07992.14 EGD91285.2 - 0.0095 15.2 0.0 0.073 12.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGD91285.2 - 0.017 14.7 0.3 0.036 13.7 0.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HMG_box_2 PF09011.10 EGD91285.2 - 0.63 10.7 2.5 1.1 9.9 1.1 2.1 2 0 0 2 2 2 0 HMG-box domain Pyr_redox_2 PF07992.14 EGD91286.1 - 2.7e-48 164.7 1.2 3.2e-48 164.4 1.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGD91286.1 - 2.1e-16 60.3 0.5 9.5e-14 51.7 0.2 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGD91286.1 - 9e-16 58.0 0.2 4.4e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGD91286.1 - 2.8e-05 23.5 0.7 6.5e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 EGD91286.1 - 5.1e-05 23.7 0.0 0.014 15.8 0.0 2.7 1 1 1 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EGD91286.1 - 0.00018 21.6 0.2 0.16 12.2 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EGD91286.1 - 0.0055 15.9 0.1 0.6 9.2 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EGD91286.1 - 0.012 14.9 0.5 2.2 7.5 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain DAO PF01266.24 EGD91286.1 - 0.028 14.0 4.4 0.88 9.1 0.1 3.4 2 2 1 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGD91286.1 - 0.033 13.5 0.3 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EGD91286.1 - 0.083 12.9 0.2 8.5 6.4 0.0 2.9 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 EGD91286.1 - 0.18 10.8 5.4 2 7.4 0.1 3.5 3 1 2 5 5 5 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGD91286.1 - 0.36 9.9 5.0 0.37 9.8 0.3 2.6 2 2 0 2 2 2 0 FAD binding domain APH PF01636.23 EGD91288.1 - 7.4e-14 52.3 0.0 1.2e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD91288.1 - 3.2e-10 40.0 0.0 7.8e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 EGD91288.1 - 0.0043 16.4 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain DUF1679 PF07914.11 EGD91288.1 - 0.056 12.3 0.0 0.68 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Sulfotransfer_4 PF17784.1 EGD91289.1 - 3.2e-64 216.7 0.3 3.9e-64 216.4 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain DUF2116 PF09889.9 EGD91289.1 - 0.0096 15.9 0.6 0.018 15.0 0.6 1.4 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) SKA2 PF16740.5 EGD91290.1 - 0.096 12.5 0.2 0.22 11.3 0.1 1.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Astro_capsid_p PF12226.8 EGD91291.2 - 0.84 8.7 7.1 1 8.4 7.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RNA_pol_3_Rpc31 PF11705.8 EGD91291.2 - 2.7 8.2 12.7 3.4 7.9 12.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Peptidase_S8 PF00082.22 EGD91292.1 - 3e-33 115.4 2.4 5.2e-33 114.6 2.4 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EGD91292.1 - 7.8e-29 99.5 0.9 1.5e-28 98.6 0.9 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Mucin PF01456.17 EGD91292.1 - 2.3 8.2 12.4 4.8 7.2 12.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Metallophos PF00149.28 EGD91293.1 - 5.8e-11 43.3 0.3 1.1e-10 42.4 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGD91293.1 - 0.0013 19.0 0.0 0.014 15.6 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PX PF00787.24 EGD91294.1 - 8.8e-19 67.6 0.4 2.2e-18 66.3 0.4 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EGD91294.1 - 6.9e-12 45.4 6.2 2.5e-05 23.9 0.1 2.1 1 1 0 2 2 2 2 Vps5 C terminal like DUF1664 PF07889.12 EGD91294.1 - 0.033 14.2 0.4 2.1 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ALC PF17527.2 EGD91294.1 - 0.047 13.3 0.5 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Phage ALC protein CNOT11 PF10155.9 EGD91294.1 - 0.17 12.0 0.3 0.76 9.9 0.3 2.1 1 1 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 Occludin_ELL PF07303.13 EGD91294.1 - 0.2 12.4 3.0 2.7 8.8 0.0 2.8 3 0 0 3 3 3 0 Occludin homology domain FAD_binding_3 PF01494.19 EGD91296.2 - 6.2e-17 61.9 0.0 5.6e-15 55.4 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EGD91296.2 - 0.0099 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase tRNA-synt_His PF13393.6 EGD91297.2 - 6.5e-36 124.2 0.0 9.4e-30 103.9 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EGD91297.2 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGD91297.2 - 3.1e-05 24.0 0.0 6e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 EGD91297.2 - 0.002 17.7 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs UCH PF00443.29 EGD91299.1 - 4.1e-55 187.0 0.7 4.1e-55 187.0 0.7 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGD91299.1 - 9.1e-27 94.5 2.8 9.4e-26 91.2 2.8 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Nop53 PF07767.11 EGD91299.1 - 1.6 8.1 25.4 0.91 8.8 21.7 2.3 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CAF-1_p150 PF11600.8 EGD91299.1 - 5.9 6.6 29.9 17 5.1 29.9 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Yos1 PF08571.10 EGD91300.2 - 6.2e-33 112.9 1.0 7.9e-33 112.6 1.0 1.1 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.17 EGD91301.2 - 5.6e-25 88.4 8.0 6.8e-25 88.1 8.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1772 PF08592.11 EGD91301.2 - 2.6 8.3 8.1 0.19 12.0 3.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Dynamitin PF04912.14 EGD91302.1 - 3e-73 247.4 12.8 1.3e-71 242.0 12.8 2.1 1 1 0 1 1 1 1 Dynamitin APG6_N PF17675.1 EGD91302.1 - 0.00037 21.0 11.0 0.31 11.6 2.2 3.3 3 0 0 3 3 3 2 Apg6 coiled-coil region MnmE_helical PF12631.7 EGD91302.1 - 0.0018 18.4 2.6 0.025 14.7 0.1 2.2 2 0 0 2 2 2 1 MnmE helical domain Jnk-SapK_ap_N PF09744.9 EGD91302.1 - 0.0026 18.0 12.4 0.012 15.9 0.7 3.0 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 EGD91302.1 - 0.0038 17.3 2.8 0.0038 17.3 2.8 3.6 4 0 0 4 4 3 1 TPR/MLP1/MLP2-like protein DUF2203 PF09969.9 EGD91302.1 - 0.0051 17.5 5.3 0.36 11.6 0.2 3.6 4 0 0 4 4 3 1 Uncharacterized conserved protein (DUF2203) DUF2408 PF10303.9 EGD91302.1 - 0.0067 17.0 5.3 0.8 10.3 0.4 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF2408) DivIC PF04977.15 EGD91302.1 - 0.0074 16.0 14.1 0.034 13.9 1.2 3.4 3 0 0 3 3 3 1 Septum formation initiator SlyX PF04102.12 EGD91302.1 - 0.011 16.3 12.9 0.08 13.6 0.5 4.3 4 0 0 4 4 4 0 SlyX SOGA PF11365.8 EGD91302.1 - 0.011 16.8 8.4 0.12 13.5 1.7 3.2 3 0 0 3 3 3 0 Protein SOGA Plant_NMP1 PF06694.11 EGD91302.1 - 0.014 14.5 0.2 0.45 9.6 0.0 2.7 3 0 0 3 3 3 0 Plant nuclear matrix protein 1 (NMP1) DUF812 PF05667.11 EGD91302.1 - 0.016 14.1 0.3 0.016 14.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) SKA2 PF16740.5 EGD91302.1 - 0.023 14.5 3.9 0.28 11.0 0.0 3.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DHR10 PF18595.1 EGD91302.1 - 0.028 14.5 0.9 0.028 14.5 0.9 3.3 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain pPIWI_RE_REase PF18154.1 EGD91302.1 - 0.029 14.3 0.2 0.065 13.2 0.2 1.5 1 0 0 1 1 1 0 REase associating with pPIWI_RE DUF4200 PF13863.6 EGD91302.1 - 0.038 14.4 12.9 0.59 10.5 3.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF4618 PF15397.6 EGD91302.1 - 0.038 13.4 2.7 0.95 8.8 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Laminin_II PF06009.12 EGD91302.1 - 0.1 12.6 0.4 0.1 12.6 0.4 3.1 3 1 0 3 3 3 0 Laminin Domain II OmpH PF03938.14 EGD91302.1 - 0.1 12.9 10.1 0.36 11.2 2.5 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) ADIP PF11559.8 EGD91302.1 - 0.11 12.6 9.5 0.9 9.6 0.5 3.3 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.6 EGD91302.1 - 0.12 12.9 13.1 3.5 8.1 0.9 4.0 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 EGD91302.1 - 0.13 11.6 16.5 3.3 7.0 0.9 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.9 EGD91302.1 - 0.16 11.9 8.8 1.1 9.1 0.8 2.7 3 0 0 3 3 2 0 Axonemal dynein light chain DUF16 PF01519.16 EGD91302.1 - 0.16 12.4 4.1 0.18 12.3 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF16 Cob_adeno_trans PF01923.18 EGD91302.1 - 0.21 11.7 4.3 35 4.5 0.4 3.2 3 0 0 3 3 3 0 Cobalamin adenosyltransferase FH2 PF02181.23 EGD91302.1 - 0.23 10.6 4.7 0.17 11.0 0.2 2.6 3 0 0 3 3 3 0 Formin Homology 2 Domain Spc7 PF08317.11 EGD91302.1 - 0.27 10.1 9.6 0.13 11.1 1.2 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.9 EGD91302.1 - 0.33 9.8 5.1 2.2 7.0 0.4 2.9 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain DUF1664 PF07889.12 EGD91302.1 - 0.55 10.3 3.6 0.73 9.9 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Csm1_N PF18504.1 EGD91302.1 - 0.57 10.6 14.1 2.6 8.5 2.3 3.4 3 0 0 3 3 3 0 Csm1 N-terminal domain Muted PF14942.6 EGD91302.1 - 0.58 10.5 9.8 2.3 8.6 1.0 3.2 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein FapA PF03961.13 EGD91302.1 - 0.63 8.6 2.1 7.3 5.1 0.1 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A Prefoldin_2 PF01920.20 EGD91302.1 - 0.64 10.0 13.5 2.3 8.2 3.4 3.4 3 1 0 3 3 3 0 Prefoldin subunit Spectrin PF00435.21 EGD91302.1 - 0.8 10.2 8.5 22 5.6 1.7 3.4 3 0 0 3 3 3 0 Spectrin repeat LPP PF04728.13 EGD91302.1 - 0.82 10.1 14.9 0.54 10.7 0.6 4.4 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Spc24 PF08286.11 EGD91302.1 - 0.85 9.9 13.5 3.4 8.0 2.0 3.6 4 0 0 4 4 3 0 Spc24 subunit of Ndc80 Cnn_1N PF07989.11 EGD91302.1 - 1 9.5 9.2 4.9 7.4 0.7 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 KxDL PF10241.9 EGD91302.1 - 1.1 9.5 4.6 0.54 10.6 0.4 2.5 3 0 0 3 3 2 0 Uncharacterized conserved protein Golgin_A5 PF09787.9 EGD91302.1 - 1.2 8.6 8.2 0.88 9.0 1.7 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 GrpE PF01025.19 EGD91302.1 - 1.5 8.4 8.6 5.2 6.7 1.0 3.0 3 0 0 3 3 3 0 GrpE Atg14 PF10186.9 EGD91302.1 - 1.7 7.6 7.5 3.1 6.8 0.2 2.6 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 JIP_LZII PF16471.5 EGD91302.1 - 1.8 8.8 13.8 0.57 10.4 3.6 3.4 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II TMPIT PF07851.13 EGD91302.1 - 1.9 7.7 2.9 2.1 7.5 0.4 2.1 2 0 0 2 2 2 0 TMPIT-like protein PRKG1_interact PF15898.5 EGD91302.1 - 1.9 9.4 11.6 2.2 9.2 1.6 3.3 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain FliD_C PF07195.12 EGD91302.1 - 2 7.8 6.1 0.55 9.6 1.9 2.1 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF724 PF05266.14 EGD91302.1 - 2.2 8.1 6.6 5.7 6.7 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF724) ZapB PF06005.12 EGD91302.1 - 2.4 8.7 12.8 14 6.2 3.0 3.5 3 0 0 3 3 3 0 Cell division protein ZapB DUF3584 PF12128.8 EGD91302.1 - 3.1 5.2 13.4 1.3 6.4 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) COG2 PF06148.11 EGD91302.1 - 4.4 7.4 5.5 2.7 8.1 0.3 2.7 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BLOC1_2 PF10046.9 EGD91302.1 - 4.8 7.6 6.9 3.1 8.2 0.5 3.2 4 1 0 4 4 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 EGD91302.1 - 9 6.6 13.1 0.62 10.3 1.1 3.5 3 1 1 4 4 3 0 Haemolysin XhlA DUF4337 PF14235.6 EGD91302.1 - 9.1 6.4 12.3 5.2 7.2 0.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) RPN7 PF10602.9 EGD91302.1 - 9.2 5.9 8.7 0.21 11.3 1.1 2.0 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Peptidase_M24 PF00557.24 EGD91304.1 - 4.3e-38 131.1 0.5 6.1e-38 130.6 0.5 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Aldedh PF00171.22 EGD91305.1 - 7.6e-137 456.6 0.8 9.9e-137 456.2 0.8 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 EGD91305.1 - 0.037 14.0 0.6 0.075 13.0 0.6 1.5 1 0 0 1 1 1 0 WTAP/Mum2p family Calreticulin PF00262.18 EGD91306.1 - 1.2e-172 573.9 15.8 1.2e-172 573.9 15.8 1.6 2 0 0 2 2 2 1 Calreticulin family Aldolase_II PF00596.21 EGD91307.1 - 1.5e-43 148.9 0.0 1.8e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.10 EGD91308.1 - 4.7e-89 298.0 7.1 4.7e-89 298.0 7.1 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 EGD91308.1 - 1.9e-25 89.0 0.2 5e-25 87.7 0.0 1.8 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 EGD91308.1 - 0.035 13.8 6.4 0.21 11.3 2.8 2.5 1 1 1 2 2 2 0 BAR domain of APPL family TFIIA PF03153.13 EGD91308.1 - 0.22 11.5 0.1 0.22 11.5 0.1 3.1 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit NifQ PF04891.12 EGD91308.1 - 0.35 11.2 1.9 0.81 10.0 1.9 1.5 1 0 0 1 1 1 0 NifQ PilJ PF13675.6 EGD91308.1 - 6.5 6.8 9.1 0.29 11.2 0.4 3.0 4 0 0 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Flavin_Reduct PF01613.18 EGD91310.1 - 1.3e-23 83.8 2.1 1.3e-23 83.8 2.1 1.9 2 1 0 2 2 2 1 Flavin reductase like domain Tweety PF04906.13 EGD91311.1 - 4.1 6.0 6.1 3.8 6.1 4.8 1.5 1 1 0 1 1 1 0 Tweety LMBR1 PF04791.16 EGD91311.1 - 4.2 6.2 5.0 8.3 5.2 5.0 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein Atg14 PF10186.9 EGD91311.1 - 5 6.1 20.6 15 4.5 20.6 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 4HBT_2 PF13279.6 EGD91312.2 - 1.9e-15 57.4 0.0 2.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily PspB PF06667.12 EGD91312.2 - 0.037 14.1 0.2 0.059 13.4 0.2 1.3 1 0 0 1 1 1 0 Phage shock protein B Complex1_LYR_2 PF13233.6 EGD91313.2 - 9.2e-06 26.3 0.8 1.2e-05 25.9 0.8 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGD91313.2 - 2.7e-05 24.1 0.1 4.2e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Methyltransf_25 PF13649.6 EGD91314.1 - 1.7e-12 47.9 0.0 3.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD91314.1 - 7.6e-11 42.5 0.0 1.9e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD91314.1 - 9.8e-08 31.9 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD91314.1 - 8.4e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGD91314.1 - 2e-05 25.2 0.2 0.00014 22.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD91314.1 - 4.7e-05 23.3 0.0 9.5e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Exo_endo_phos PF03372.23 EGD91315.2 - 2e-22 79.9 0.0 1.2e-21 77.3 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 EGD91315.2 - 5.9e-15 54.8 27.5 1.1e-07 31.5 7.7 2.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EGD91315.2 - 9e-11 41.8 9.8 2.9e-06 27.5 1.6 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGD91315.2 - 0.038 13.5 0.2 0.067 12.7 0.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 EGD91315.2 - 0.2 12.3 5.0 4.5 8.2 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat MFS_1 PF07690.16 EGD91317.1 - 1.1e-47 162.8 48.2 3.7e-47 161.0 47.8 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGD91317.1 - 4.5e-24 84.8 12.4 6.2e-21 74.5 10.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGD91317.1 - 4.2e-19 68.7 2.9 4.2e-19 68.7 2.9 2.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EGD91317.1 - 6.2e-06 25.8 7.7 6.2e-06 25.8 7.7 3.1 3 1 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB EptA_B_N PF08019.12 EGD91317.1 - 0.0046 16.8 0.1 0.0046 16.8 0.1 3.0 4 0 0 4 4 4 1 Phosphoethanolamine transferase EptA/EptB Peptidase_M56 PF05569.11 EGD91317.1 - 0.026 13.7 0.2 0.046 12.9 0.2 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 OATP PF03137.20 EGD91317.1 - 0.69 8.1 15.3 0.091 11.0 3.7 3.3 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family GCD14 PF08704.10 EGD91318.1 - 6.4e-07 29.3 0.0 0.00055 19.7 0.0 2.4 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 EGD91318.1 - 3.3e-06 26.8 1.9 6.2e-06 26.0 0.8 2.1 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_31 PF13847.6 EGD91318.1 - 0.02 14.7 0.0 6.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain HEPN_RnaseLS PF18869.1 EGD91318.1 - 0.077 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 RnaseLS-like HEPN Methyltransf_25 PF13649.6 EGD91318.1 - 0.097 13.4 0.0 2.7 8.8 0.0 2.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGD91318.1 - 0.14 12.9 0.0 19 6.0 0.0 2.8 2 1 1 3 3 3 0 Methyltransferase domain Metallophos PF00149.28 EGD91319.1 - 6.7e-19 69.2 2.2 7.1e-19 69.1 0.3 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGD91319.1 - 1.3e-06 28.7 0.0 0.0017 18.5 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain NAD_binding_6 PF08030.12 EGD91320.2 - 0.00017 21.8 0.4 0.0054 16.9 0.4 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EGD91320.2 - 0.00058 20.5 0.1 0.13 12.9 0.1 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain MARVEL PF01284.23 EGD91321.1 - 0.00046 20.2 2.0 0.00064 19.8 2.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain TMEM156 PF15106.6 EGD91321.1 - 0.031 13.7 0.5 0.048 13.1 0.5 1.2 1 0 0 1 1 1 0 TMEM156 protein family EF-1_beta_acid PF10587.9 EGD91321.1 - 0.5 10.9 4.7 0.88 10.1 4.7 1.3 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region COesterase PF00135.28 EGD91322.1 - 2.6e-54 185.0 0.0 5.1e-54 184.0 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGD91322.1 - 8.2e-07 29.1 0.2 4.7e-06 26.6 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold CSN7a_helixI PF18392.1 EGD91324.1 - 0.0012 18.7 0.1 0.0022 17.9 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 EGD91324.1 - 0.0021 18.6 0.0 0.0037 17.8 0.0 1.3 1 0 0 1 1 1 1 PCI domain RGS PF00615.19 EGD91325.1 - 4.9e-13 49.4 0.0 4e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Bromodomain PF00439.25 EGD91326.2 - 1.1e-24 86.3 1.0 2.1e-24 85.4 1.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EGD91326.2 - 2.9e-08 33.9 0.0 5.8e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGD91326.2 - 9.9e-07 28.7 0.1 1.8e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGD91326.2 - 0.00034 21.0 0.1 0.00061 20.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SbcCD_C PF13558.6 EGD91328.2 - 7.1e-07 29.4 0.0 2e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit 2OG-FeII_Oxy_2 PF13532.6 EGD91328.2 - 0.12 12.5 2.4 0.21 11.7 0.8 2.4 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily PPP4R2 PF09184.11 EGD91329.2 - 6.9e-11 42.3 0.0 1.1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 PPP4R2 DUF3480 PF11979.8 EGD91330.1 - 0.023 13.6 0.1 0.85 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3480) zf-C2H2 PF00096.26 EGD91331.2 - 1.5e-12 47.2 13.9 3.9e-06 27.0 2.4 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGD91331.2 - 7.5e-11 42.0 10.1 1.4e-06 28.4 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGD91331.2 - 1.5e-08 34.8 11.4 0.00092 19.9 1.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGD91331.2 - 8.3e-07 28.9 5.2 0.0022 17.9 0.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGD91331.2 - 5.2e-06 26.6 0.2 0.067 13.5 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGD91331.2 - 0.00016 21.9 1.4 0.013 15.9 0.3 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EGD91331.2 - 0.00031 20.4 5.6 0.095 12.5 0.6 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 EGD91331.2 - 0.019 15.5 1.3 0.048 14.2 1.3 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 EGD91331.2 - 0.097 13.0 1.6 0.19 12.1 1.6 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 EGD91331.2 - 0.16 12.5 2.1 4.1 7.9 0.4 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 EGD91331.2 - 0.74 10.1 2.3 14 6.0 0.2 2.4 1 1 1 2 2 2 0 LIM domain C5HCH PF17982.1 EGD91331.2 - 2.5 8.4 6.3 18 5.6 1.2 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain Pkinase PF00069.25 EGD91334.2 - 3.1e-34 118.5 0.0 4.8e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD91334.2 - 7.1e-13 48.4 0.0 1e-11 44.7 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD91334.2 - 6e-05 22.0 0.0 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGD91334.2 - 0.00072 19.0 0.0 0.0021 17.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGD91334.2 - 0.0022 18.0 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kelch_4 PF13418.6 EGD91336.1 - 3e-05 23.9 0.3 0.033 14.2 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EGD91336.1 - 0.00027 20.8 0.0 0.025 14.6 0.0 2.9 2 0 0 2 2 2 1 Kelch motif Mid2 PF04478.12 EGD91336.1 - 0.0004 20.2 0.0 0.00095 19.0 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Kelch_3 PF13415.6 EGD91336.1 - 0.0032 17.7 1.1 6.7 7.1 0.1 4.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EGD91336.1 - 0.0055 16.9 0.7 0.74 10.2 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 EGD91336.1 - 0.011 15.7 1.8 0.67 10.0 0.0 3.9 3 0 0 3 3 3 0 Kelch motif SKG6 PF08693.10 EGD91336.1 - 0.03 13.7 3.2 0.058 12.8 3.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain BPL_LplA_LipB PF03099.19 EGD91337.2 - 5.8e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.21 EGD91338.1 - 1.1e-139 464.7 0.0 1.3e-139 464.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Ima1_N PF09779.9 EGD91339.1 - 3.1e-37 128.4 7.7 3.1e-37 128.4 7.7 1.9 2 0 0 2 2 2 1 Ima1 N-terminal domain DZR PF12773.7 EGD91339.1 - 0.082 12.9 4.4 1.7 8.8 0.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 EGD91339.1 - 0.61 10.1 3.6 0.29 11.1 0.8 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 EGD91339.1 - 0.84 9.7 11.1 0.063 13.3 4.3 2.5 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Alg14 PF08660.11 EGD91340.1 - 6.7e-52 175.9 0.0 9.5e-52 175.4 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like PNK3P PF08645.11 EGD91342.2 - 8.7e-43 145.8 0.1 2.1e-42 144.6 0.1 1.6 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase PGP_phosphatase PF09419.10 EGD91342.2 - 0.025 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Med18 PF09637.10 EGD91343.1 - 9.4e-43 146.8 0.0 1.1e-42 146.7 0.0 1.0 1 0 0 1 1 1 1 Med18 protein S36_mt PF10937.8 EGD91344.1 - 1.7e-42 145.6 0.4 2e-42 145.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial DUF647 PF04884.14 EGD91347.1 - 1.2e-111 372.2 1.2 1.7e-111 371.7 1.2 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Mntp PF02659.15 EGD91347.1 - 0.019 14.8 0.5 0.046 13.5 0.2 1.8 2 0 0 2 2 2 0 Putative manganese efflux pump RGS PF00615.19 EGD91351.1 - 1.9e-11 44.2 0.0 2.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.25 EGD91355.2 - 1.3e-27 96.8 0.0 1.7e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD91355.2 - 2.2e-14 53.4 0.0 3.2e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD91355.2 - 1.9e-07 30.2 0.1 2.7e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Rtt106 PF08512.12 EGD91356.1 - 9.7e-31 106.0 0.0 1.9e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 EGD91356.1 - 0.014 15.4 0.0 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain PPP4R2 PF09184.11 EGD91356.1 - 8.7 5.8 11.7 14 5.2 11.7 1.3 1 0 0 1 1 1 0 PPP4R2 KOW PF00467.29 EGD91357.1 - 2.4e-06 27.3 0.3 4.9e-06 26.3 0.3 1.5 1 0 0 1 1 1 1 KOW motif SH3_13 PF18335.1 EGD91357.1 - 0.057 13.3 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Ras PF00071.22 EGD91358.1 - 1.4e-55 187.3 0.0 1.6e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD91358.1 - 3.3e-22 79.0 0.0 5e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD91358.1 - 1.1e-06 28.3 0.0 1.8e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGD91358.1 - 0.0024 17.3 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit baeRF_family3 PF18845.1 EGD91358.1 - 0.046 14.0 0.0 0.088 13.1 0.0 1.4 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 Gtr1_RagA PF04670.12 EGD91358.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Podoplanin PF05808.11 EGD91360.1 - 0.00062 19.9 0.5 0.00062 19.9 0.5 1.7 1 1 1 2 2 2 1 Podoplanin MGC-24 PF05283.11 EGD91360.1 - 0.00063 20.2 1.3 0.00063 20.2 1.3 2.0 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4690 PF15756.5 EGD91360.1 - 0.0054 17.3 0.7 0.0054 17.3 0.7 1.8 2 0 0 2 2 2 1 Small Novel Rich in Cartilage Syndecan PF01034.20 EGD91360.1 - 0.038 13.9 0.9 0.069 13.1 0.9 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 EGD91360.1 - 0.054 12.9 1.2 0.11 11.9 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Aldedh PF00171.22 EGD91361.1 - 4.3e-144 480.5 0.0 5.3e-144 480.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Hydant_A_N PF05378.13 EGD91361.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region DUF1712 PF08217.11 EGD91363.2 - 4.5e-12 45.3 0.0 2.3e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.19 EGD91364.2 - 1.1e-22 80.7 0.0 1.7e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase adh_short_C2 PF13561.6 EGD91365.1 - 1.6e-43 148.9 0.1 2e-43 148.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD91365.1 - 4.1e-42 143.9 0.1 5.3e-42 143.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD91365.1 - 5.5e-11 42.7 0.4 8e-11 42.2 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGD91365.1 - 0.026 14.0 0.3 0.14 11.6 0.2 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGD91365.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein EMP24_GP25L PF01105.24 EGD91366.1 - 3.1e-51 173.9 0.0 4.1e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HXXSHH PF07586.11 EGD91366.1 - 0.078 12.5 1.4 0.11 12.1 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1552) TMEMspv1-c74-12 PF11044.8 EGD91366.1 - 0.1 12.6 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PspB PF06667.12 EGD91366.1 - 0.22 11.6 0.6 0.45 10.6 0.6 1.5 1 0 0 1 1 1 0 Phage shock protein B SANT_DAMP1_like PF16282.5 EGD91367.2 - 7.8e-31 106.1 1.1 1.5e-30 105.2 1.1 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 EGD91367.2 - 0.0025 17.7 7.1 0.0025 17.7 7.1 3.0 1 1 1 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF1704 PF08014.11 EGD91367.2 - 0.04 12.9 0.9 0.08 11.9 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) Myb_DNA-binding PF00249.31 EGD91367.2 - 0.083 13.1 0.0 0.47 10.7 0.0 2.4 2 1 0 2 2 2 0 Myb-like DNA-binding domain UPF0242 PF06785.11 EGD91367.2 - 1.2 9.2 9.6 0.51 10.4 1.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Meth_synt_2 PF01717.18 EGD91369.1 - 4.8e-151 502.6 0.0 1.4e-147 491.2 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EGD91369.1 - 2.7e-118 395.0 0.0 2e-112 375.8 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EGD91369.1 - 2.6e-05 23.6 0.0 0.024 13.8 0.0 2.6 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) VbhA PF18495.1 EGD91369.1 - 0.065 13.1 0.1 16 5.4 0.0 2.8 2 0 0 2 2 2 0 Antitoxin VbhA SHOCT PF09851.9 EGD91369.1 - 0.85 9.4 5.7 0.48 10.2 0.2 3.0 3 0 0 3 3 3 0 Short C-terminal domain DUF5302 PF17227.2 EGD91369.1 - 1.3 10.1 3.4 3.3 8.8 3.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5302) Steroid_dh PF02544.16 EGD91370.1 - 6.7e-09 35.9 1.5 0.0043 17.0 0.1 3.8 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EGD91370.1 - 0.03 13.8 0.3 0.2 11.1 0.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Ufd2P_core PF10408.9 EGD91371.2 - 1.4e-205 684.6 15.7 1.8e-205 684.3 15.7 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EGD91371.2 - 7.4e-28 96.5 1.8 3.6e-27 94.3 0.4 2.6 2 0 0 2 2 2 1 U-box domain CCDC53 PF10152.9 EGD91371.2 - 0.72 10.3 5.5 0.59 10.6 3.4 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF2452 PF10504.9 EGD91372.1 - 0.24 10.9 0.0 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2452) DUF1977 PF09320.11 EGD91373.1 - 1.4e-31 108.9 0.1 2.6e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EGD91373.1 - 1.5e-22 79.5 0.4 2.6e-22 78.7 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Aim19 PF10315.9 EGD91374.1 - 5.3e-06 26.7 0.6 1.2e-05 25.6 0.6 1.7 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 CTP_transf_like PF01467.26 EGD91375.1 - 0.00035 20.8 0.0 0.0015 18.8 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase-like Ydc2-catalyt PF09159.10 EGD91377.1 - 7.3e-91 304.8 0.0 9.3e-91 304.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 EGD91377.1 - 3.3e-05 24.1 0.0 0.8 9.8 0.0 3.3 3 0 0 3 3 3 2 Poxvirus A22 protein SAP PF02037.27 EGD91377.1 - 6.3e-05 22.6 0.6 0.00013 21.7 0.6 1.6 1 0 0 1 1 1 1 SAP domain Tcp11 PF05794.13 EGD91378.1 - 6.3e-97 325.4 0.0 9.2e-97 324.9 0.0 1.2 1 0 0 1 1 1 1 T-complex protein 11 Peptidase_S10 PF00450.22 EGD91380.1 - 2.9e-78 264.1 0.0 1.4e-77 261.9 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase SOG2 PF10428.9 EGD91381.1 - 3.1e-105 353.3 2.6 3.1e-105 353.3 2.6 4.2 3 1 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.7 EGD91381.1 - 5.2e-13 49.0 5.1 5.6e-05 23.4 0.5 3.9 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGD91381.1 - 1.9e-12 46.7 6.3 2.7e-07 30.2 0.5 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EGD91381.1 - 0.028 14.9 6.7 40 5.3 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EGD91381.1 - 0.058 13.5 5.2 3.3 8.0 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat MRP-S25 PF13741.6 EGD91383.1 - 2.1e-79 266.3 6.1 2.5e-79 266.1 6.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EGD91383.1 - 0.062 13.6 3.8 15 5.9 3.1 3.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 PPR_2 PF13041.6 EGD91384.1 - 5.5e-10 39.3 0.3 0.0097 16.1 0.0 4.7 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.20 EGD91384.1 - 4.6e-07 29.7 1.3 0.25 11.7 0.1 4.4 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 EGD91384.1 - 0.00062 19.2 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EGD91384.1 - 0.081 13.0 0.3 4.7 7.3 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain ESSS PF10183.9 EGD91384.1 - 0.083 13.1 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DEAD PF00270.29 EGD91385.1 - 9.6e-17 61.3 0.0 4.6e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD91385.1 - 1.2e-13 51.4 0.0 1.3e-10 41.6 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EGD91385.1 - 8.5e-05 23.2 1.1 8.5e-05 23.2 1.1 2.3 2 0 0 2 2 2 1 RecQ zinc-binding KH_1 PF00013.29 EGD91386.1 - 5.8e-08 32.4 0.0 4.2e-06 26.5 0.0 2.5 2 0 0 2 2 2 1 KH domain ATLF PF07737.11 EGD91386.1 - 0.16 11.2 0.0 0.56 9.5 0.0 1.7 2 0 0 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain DivIC PF04977.15 EGD91386.1 - 0.42 10.4 8.5 1.1 9.1 8.5 1.6 1 0 0 1 1 1 0 Septum formation initiator ALS_ss_C PF10369.9 EGD91387.1 - 2.8e-15 56.3 0.0 6.6e-14 51.9 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EGD91387.1 - 2.1e-12 46.6 0.2 3.7e-12 45.8 0.2 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EGD91387.1 - 5e-08 32.7 0.0 9.4e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EGD91387.1 - 0.031 14.3 0.1 11 6.0 0.0 2.6 2 0 0 2 2 2 0 ACT domain Cu-oxidase_3 PF07732.15 EGD91390.1 - 9.1e-42 141.8 0.2 1.7e-40 137.7 0.2 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGD91390.1 - 2.7e-37 127.6 6.6 5.4e-35 120.1 0.7 3.9 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 EGD91390.1 - 1.6e-26 93.3 0.0 1.2e-25 90.5 0.0 2.2 2 1 0 2 2 2 1 Multicopper oxidase OTCace PF00185.24 EGD91393.1 - 1.1e-45 155.6 0.0 1.7e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EGD91393.1 - 8.8e-44 149.1 0.0 1.3e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF3984 PF13136.6 EGD91394.1 - 9e-102 340.9 21.2 1.5e-101 340.2 21.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Ndc1_Nup PF09531.10 EGD91395.2 - 2.3e-194 647.6 2.4 2.6e-194 647.4 2.4 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 EGD91396.1 - 1e-22 80.4 8.8 1e-22 80.4 3.3 2.4 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EGD91396.1 - 1.2e-14 54.1 2.0 1.2e-14 54.1 2.0 2.2 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 EGD91396.1 - 1.1e-06 28.5 8.2 1.8e-06 27.7 8.2 1.4 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 EGD91396.1 - 2.3e-05 24.1 1.6 0.00057 19.6 0.3 2.6 2 1 0 2 2 2 1 Synaptobrevin T3SSipB PF16535.5 EGD91396.1 - 0.0062 17.0 4.8 0.036 14.6 3.4 2.4 2 0 0 2 2 2 1 Type III cell invasion protein SipB DUF334 PF03904.13 EGD91396.1 - 0.035 13.6 4.1 0.44 10.1 1.7 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF334) SepF PF04472.12 EGD91396.1 - 0.055 13.7 0.0 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 Cell division protein SepF Fib_alpha PF08702.10 EGD91396.1 - 0.23 11.6 2.9 0.55 10.4 0.2 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 EGD91396.1 - 0.24 10.0 8.8 0.32 9.6 8.8 1.2 1 0 0 1 1 1 0 AAA domain DUF883 PF05957.13 EGD91396.1 - 0.28 11.8 11.5 0.54 10.9 0.4 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF16 PF01519.16 EGD91396.1 - 0.66 10.5 5.7 0.86 10.1 0.8 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 Prominin PF05478.11 EGD91396.1 - 2.5 6.0 6.5 1.9 6.4 0.9 2.1 1 1 1 2 2 2 0 Prominin Cyto_heme_lyase PF01265.17 EGD91397.1 - 7.7e-40 137.3 6.8 2.2e-35 122.6 0.2 2.6 2 1 0 2 2 2 2 Cytochrome c/c1 heme lyase MDD_C PF18376.1 EGD91398.1 - 2.9e-61 206.5 0.0 3.9e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EGD91398.1 - 2.8e-10 40.3 1.7 6.7e-10 39.1 1.7 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain IKI3 PF04762.12 EGD91399.1 - 2.4e-299 995.6 0.0 2.8e-299 995.3 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EGD91399.1 - 0.00021 21.5 0.1 2.1 8.7 0.0 4.3 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain COX7C PF02935.16 EGD91400.1 - 1.1e-22 80.1 3.6 1.3e-22 79.8 3.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Cut8 PF08559.10 EGD91402.1 - 1.8e-82 276.6 0.0 2.3e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein HalOD1 PF18545.1 EGD91402.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Halobacterial output domain 1 DUF1631 PF07793.11 EGD91402.1 - 0.16 10.4 0.7 0.2 10.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Motile_Sperm PF00635.26 EGD91403.1 - 2.6e-25 88.4 0.1 5.1e-25 87.4 0.1 1.5 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Trypan_PARP PF05887.11 EGD91403.1 - 0.003 17.5 2.0 0.0053 16.7 2.0 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) ASH PF15780.5 EGD91403.1 - 0.0055 16.9 0.1 0.032 14.4 0.0 2.1 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin UBX PF00789.20 EGD91404.2 - 3e-06 27.3 0.0 7.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain Selenoprotein_S PF06936.11 EGD91404.2 - 0.3 10.9 10.6 0.48 10.2 10.6 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) RNB PF00773.19 EGD91404.2 - 0.3 10.4 3.6 0.41 9.9 3.6 1.2 1 0 0 1 1 1 0 RNB domain SOBP PF15279.6 EGD91404.2 - 0.55 10.8 3.7 0.62 10.6 3.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.17 EGD91404.2 - 1.2 7.9 6.6 1.2 7.8 6.6 1.1 1 0 0 1 1 1 0 Presenilin Ureide_permease PF07168.11 EGD91404.2 - 2.6 6.7 4.2 3.3 6.3 4.2 1.1 1 0 0 1 1 1 0 Ureide permease DivIC PF04977.15 EGD91404.2 - 4.2 7.2 17.0 0.065 13.0 6.5 2.4 1 1 1 2 2 2 0 Septum formation initiator Ntox1 PF15500.6 EGD91404.2 - 4.5 7.7 12.5 4.5 7.7 11.2 1.7 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 AAA_11 PF13086.6 EGD91404.2 - 6.2 6.5 11.4 8.5 6.1 11.4 1.2 1 0 0 1 1 1 0 AAA domain Peptidase_C48 PF02902.19 EGD91404.2 - 6.3 6.6 7.2 6.8 6.5 4.4 2.2 2 1 0 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain O-antigen_lig PF13425.6 EGD91404.2 - 7.4 5.2 7.6 9.9 4.8 7.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Aa_trans PF01490.18 EGD91407.1 - 1.6e-78 264.2 30.7 2e-78 264.0 30.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3043 PF11241.8 EGD91407.1 - 0.47 10.5 3.9 31 4.6 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) Trypsin_2 PF13365.6 EGD91408.1 - 2.6e-05 25.2 0.0 0.0017 19.2 0.0 2.8 2 1 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.11 EGD91408.1 - 0.0012 17.4 0.0 0.0016 17.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 Peptidase_S32 PF05579.13 EGD91408.1 - 0.039 13.2 0.0 0.086 12.0 0.0 1.5 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 DUF4667 PF15700.5 EGD91408.1 - 0.14 12.2 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Y_phosphatase2 PF03162.13 EGD91410.2 - 9.2e-42 142.4 0.0 1.2e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGD91410.2 - 7.6e-09 35.9 0.0 1.2e-08 35.2 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EGD91410.2 - 3.1e-06 27.0 0.0 4.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGD91410.2 - 0.00079 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF1133 PF06576.11 EGD91410.2 - 0.069 12.5 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) PTPlike_phytase PF14566.6 EGD91410.2 - 0.092 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate TatD_DNase PF01026.21 EGD91412.2 - 5e-42 144.0 0.0 5.9e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.18 EGD91413.1 - 2.3e-112 375.5 0.0 2.8e-112 375.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EGD91413.1 - 4.4e-18 65.2 0.0 8e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EGD91413.1 - 0.00037 19.7 0.0 0.00058 19.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 EGD91413.1 - 0.0013 18.1 0.0 0.083 12.2 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 EGD91413.1 - 0.0014 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGD91413.1 - 0.007 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CbiJ PF02571.14 EGD91413.1 - 0.14 11.6 0.0 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK SAP PF02037.27 EGD91414.1 - 9e-10 38.1 0.0 1.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 SAP domain PCMT PF01135.19 EGD91414.1 - 0.18 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNA_pol_Rpb1_5 PF04998.17 EGD91415.2 - 3e-79 266.2 0.9 3e-79 266.2 0.9 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGD91415.2 - 6.9e-72 241.1 0.0 1.3e-71 240.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 EGD91415.2 - 1.1e-43 149.8 0.0 2.1e-43 148.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 EGD91415.2 - 5.2e-34 117.4 0.0 1.1e-33 116.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGD91415.2 - 1.5e-25 89.3 0.5 4.7e-25 87.6 0.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Asp PF00026.23 EGD91416.2 - 4.5e-65 220.1 0.6 5.3e-65 219.9 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGD91416.2 - 1.8e-05 25.1 1.6 0.00074 19.8 2.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGD91416.2 - 0.017 15.8 0.5 3.9 8.2 0.1 3.1 2 2 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 EGD91416.2 - 0.039 14.5 0.0 8.6 7.0 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EGD91416.2 - 0.04 13.7 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DSPc PF00782.20 EGD91419.2 - 3.9e-22 78.5 0.0 5e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGD91419.2 - 0.0067 16.7 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EGD91419.2 - 0.087 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-C2H2 PF00096.26 EGD91420.1 - 0.014 15.8 3.3 0.014 15.8 3.3 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGD91420.1 - 0.015 15.7 1.2 0.015 15.7 1.2 3.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EGD91420.1 - 0.071 13.4 4.2 0.19 12.0 4.2 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF2614 PF11023.8 EGD91420.1 - 0.17 12.0 0.3 0.28 11.3 0.3 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Cytochrome_C7 PF14522.6 EGD91420.1 - 2.3 8.3 13.0 7.9 6.6 13.0 2.0 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-C2H2_4 PF13894.6 EGD91420.1 - 2.8 9.0 20.6 0.35 11.8 2.3 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger FA_desaturase PF00487.24 EGD91421.1 - 8.1e-26 91.4 10.2 1.2e-25 90.8 10.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EGD91421.1 - 2.1e-17 62.3 0.7 3.9e-17 61.4 0.7 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ABC1 PF03109.16 EGD91422.1 - 5e-33 113.8 0.0 9.2e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EGD91422.1 - 0.059 13.0 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Anp1 PF03452.14 EGD91423.1 - 3.3e-104 348.0 0.1 4.1e-104 347.7 0.1 1.1 1 0 0 1 1 1 1 Anp1 Ecm33 PF12454.8 EGD91424.1 - 1.3e-11 44.4 1.4 2.5e-11 43.5 0.4 2.1 1 1 1 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 EGD91424.1 - 1.5e-10 41.1 2.4 0.015 15.4 0.0 5.2 2 2 3 5 5 5 3 Receptor L domain LRR_4 PF12799.7 EGD91424.1 - 0.12 12.8 7.1 7.8 7.1 0.2 4.5 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) HhH-GPD PF00730.25 EGD91425.2 - 9.2e-13 48.6 0.0 1.9e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HMG14_17 PF01101.18 EGD91425.2 - 0.4 11.7 8.2 0.92 10.5 8.2 1.5 1 0 0 1 1 1 0 HMG14 and HMG17 Mito_fiss_reg PF05308.11 EGD91425.2 - 0.71 9.9 5.6 1.3 9.1 5.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator UCR_14kD PF02271.16 EGD91426.1 - 4.4e-44 148.5 0.1 5.2e-44 148.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 EGD91427.1 - 5.2e-63 209.0 2.5 2e-21 75.7 0.0 3.8 2 2 1 3 3 3 3 Mitochondrial carrier protein Androgen_recep PF02166.16 EGD91427.1 - 3.3 6.4 9.6 5.9 5.6 9.6 1.3 1 0 0 1 1 1 0 Androgen receptor SUI1 PF01253.22 EGD91429.2 - 7.5e-18 64.8 0.0 1.9e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Trypsin PF00089.26 EGD91430.1 - 2.2e-08 34.2 0.1 4.6e-08 33.1 0.1 1.4 1 1 0 1 1 1 1 Trypsin TIG PF01833.24 EGD91431.2 - 1.4e-09 37.9 0.2 4.4e-09 36.3 0.2 1.9 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.30 EGD91431.2 - 1.2e-08 34.9 6.2 0.0024 18.2 2.9 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EGD91431.2 - 6.2e-08 33.1 0.1 1.2e-07 32.2 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGD91431.2 - 4.5e-07 30.0 0.9 5.7e-05 23.3 0.6 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGD91431.2 - 4.7e-07 30.2 0.9 2e-06 28.2 0.4 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD91431.2 - 5.5e-06 26.3 0.9 0.076 13.6 0.3 2.7 2 0 0 2 2 2 2 Ankyrin repeat FA_desaturase PF00487.24 EGD91433.1 - 9.6e-24 84.6 19.2 2.7e-23 83.1 19.2 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EGD91433.1 - 4.8e-09 36.5 0.0 1.1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Rad51 PF08423.11 EGD91434.2 - 5.1e-19 68.5 0.0 1.3e-16 60.7 0.0 2.1 2 0 0 2 2 2 2 Rad51 MFS_1 PF07690.16 EGD91435.2 - 1.9e-08 33.6 9.9 1.9e-08 33.6 9.9 3.3 2 2 2 4 4 4 4 Major Facilitator Superfamily DAO PF01266.24 EGD91436.2 - 7.3e-49 167.2 0.5 8.4e-49 167.0 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGD91436.2 - 3.6e-05 23.1 0.0 6.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EGD91436.2 - 6e-05 23.2 0.5 0.00015 21.9 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EGD91436.2 - 0.0027 16.9 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Mqo PF06039.15 EGD91436.2 - 0.014 14.0 0.1 0.02 13.5 0.1 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 EGD91436.2 - 0.054 12.6 0.9 0.095 11.8 0.6 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 EGD91436.2 - 0.083 12.9 0.1 0.3 11.0 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EGD91436.2 - 0.086 12.1 0.0 0.54 9.5 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase SecD-TM1 PF13721.6 EGD91436.2 - 0.18 12.3 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 SecD export protein N-terminal TM region La PF05383.17 EGD91437.1 - 5.9e-21 74.3 0.0 1.2e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EGD91437.1 - 2.6e-05 23.9 0.0 6.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chitin_synth_2 PF03142.15 EGD91438.2 - 5.6e-24 84.7 4.1 5.6e-22 78.1 2.8 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGD91438.2 - 8.3e-15 55.2 7.7 8.3e-15 55.2 7.7 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGD91438.2 - 6.3e-11 42.6 0.2 3.1e-10 40.3 0.1 2.1 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGD91438.2 - 0.011 15.6 0.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGD91438.2 - 0.53 9.7 1.7 6.5 6.2 1.7 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 21 HSP70 PF00012.20 EGD91439.2 - 3.7e-163 543.9 1.4 2.7e-162 541.1 1.4 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGD91439.2 - 3.5e-11 42.5 0.4 6.9e-11 41.5 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EGD91439.2 - 0.0035 17.7 0.1 0.5 10.8 0.0 3.2 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 EGD91439.2 - 0.084 12.9 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGD91440.1 - 1e-69 234.8 0.5 1.5e-69 234.3 0.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGD91440.1 - 2.8e-41 140.0 0.5 6.2e-41 138.9 0.5 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EGD91440.1 - 0.007 16.2 0.2 2.8 7.9 0.1 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EGD91440.1 - 0.037 13.6 2.0 0.13 11.9 1.2 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain SMG1 PF15785.5 EGD91440.1 - 0.096 11.0 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 WLM PF08325.10 EGD91441.1 - 5.6e-50 170.1 0.0 7.7e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 EGD91441.1 - 6.1e-05 23.1 0.1 0.00046 20.3 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.9 EGD91441.1 - 0.036 13.9 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 SprT-like family LicD PF04991.13 EGD91442.1 - 3.1e-21 76.6 1.5 5.2e-17 62.8 2.4 2.1 1 1 1 2 2 2 2 LicD family MTBP_C PF14920.6 EGD91443.2 - 0.048 13.4 3.2 0.07 12.9 3.2 1.2 1 0 0 1 1 1 0 MDM2-binding LIM PF00412.22 EGD91445.2 - 0.00045 20.4 8.1 0.00045 20.4 8.1 1.9 2 0 0 2 2 2 1 LIM domain CENP-H PF05837.12 EGD91445.2 - 0.034 14.6 0.3 0.034 14.6 0.3 2.7 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Zn-ribbon_8 PF09723.10 EGD91445.2 - 0.25 11.5 7.5 1.1 9.4 1.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Fez1 PF06818.15 EGD91445.2 - 0.43 11.0 15.4 2.5 8.5 15.5 2.2 1 1 0 1 1 1 0 Fez1 TF_Zn_Ribbon PF08271.12 EGD91445.2 - 3.1 7.4 9.8 4.1 7.0 3.7 3.1 2 1 1 3 3 3 0 TFIIB zinc-binding 4HBT PF03061.22 EGD91448.1 - 7.4e-06 26.2 0.1 1.4e-05 25.4 0.1 1.5 1 1 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EGD91448.1 - 0.0055 17.0 0.0 0.0078 16.5 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Carn_acyltransf PF00755.20 EGD91449.2 - 7.1e-157 523.6 0.0 8.3e-157 523.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase UQ_con PF00179.26 EGD91451.2 - 0.023 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme AA_permease_2 PF13520.6 EGD91452.2 - 3.3e-41 141.5 19.1 4.3e-41 141.1 19.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD91452.2 - 1.7e-23 83.0 19.6 2.2e-23 82.6 19.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 EGD91452.2 - 0.14 12.3 0.8 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 Orai-1 PF07856.12 EGD91452.2 - 0.67 9.6 6.9 0.26 11.0 2.6 2.1 2 0 0 2 2 2 0 Mediator of CRAC channel activity Cyclase PF04199.13 EGD91453.2 - 9.9e-15 55.0 0.0 2.4e-14 53.7 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase Ribonuc_L-PSP PF01042.21 EGD91458.1 - 1e-38 132.0 0.1 1.1e-38 131.9 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP QRPTase_C PF01729.19 EGD91458.1 - 0.029 14.1 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain D-ser_dehydrat PF14031.6 EGD91459.2 - 9.8e-25 87.1 0.0 1.8e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EGD91459.2 - 3.5e-08 33.4 0.0 5.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Glyco_hyd_101C PF17451.2 EGD91459.2 - 0.071 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain BST2 PF16716.5 EGD91460.2 - 0.61 10.7 3.9 0.19 12.3 0.4 1.9 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Velvet PF11754.8 EGD91461.1 - 3.5e-50 171.3 0.1 1.1e-31 110.7 0.0 4.7 2 2 1 3 3 3 2 Velvet factor CAP_N PF01213.19 EGD91462.2 - 8.2 5.8 7.2 11 5.4 7.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PPTA PF01239.22 EGD91463.1 - 0.00093 18.9 6.6 0.21 11.4 1.2 3.3 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat 4F5 PF04419.14 EGD91464.2 - 1.6e-11 44.9 7.4 1.6e-11 44.9 7.4 1.7 2 0 0 2 2 2 1 4F5 protein family AA_permease_2 PF13520.6 EGD91467.2 - 7.5e-17 61.3 26.7 8.7e-17 61.1 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD91467.2 - 2e-09 36.6 18.4 2.7e-09 36.1 18.4 1.1 1 0 0 1 1 1 1 Amino acid permease TRAM_LAG1_CLN8 PF03798.16 EGD91468.2 - 3.1e-39 134.8 22.9 3.1e-39 134.8 22.9 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EGD91468.2 - 1e-13 50.7 3.4 1.4e-13 50.2 0.1 2.5 2 0 0 2 2 2 1 TRAM1-like protein RRM_1 PF00076.22 EGD91469.1 - 5.2e-15 55.0 0.0 1.4e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGD91469.1 - 0.022 14.9 0.1 0.11 12.7 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 EGD91469.1 - 0.12 12.4 0.1 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SMN PF06003.12 EGD91470.1 - 6.3e-09 35.5 3.2 3.9e-08 32.9 0.3 2.2 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) PPS_PS PF02006.16 EGD91470.1 - 0.017 14.7 0.5 0.023 14.2 0.5 1.2 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase Thiolase_N PF00108.23 EGD91471.1 - 1.4e-14 54.1 0.1 2.2e-13 50.2 0.1 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGD91471.1 - 3.9e-11 42.7 3.0 6.7e-11 41.9 0.1 2.5 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EGD91471.1 - 1.3e-07 31.3 0.1 1e-05 25.3 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EGD91471.1 - 0.003 17.2 0.1 0.0063 16.1 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 EGD91471.1 - 0.015 14.0 0.1 0.042 12.6 0.1 1.7 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Mito_carr PF00153.27 EGD91473.2 - 2.2e-31 107.6 3.1 4.9e-16 58.4 0.4 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein bZIP_2 PF07716.15 EGD91474.1 - 2.3e-13 50.0 12.1 4.2e-13 49.1 12.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EGD91474.1 - 1.2e-05 25.3 10.9 2.1e-05 24.5 10.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor TFIIA PF03153.13 EGD91474.1 - 0.76 9.7 32.2 1.2 9.0 32.2 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC106 PF15794.5 EGD91474.1 - 0.78 9.4 16.5 1.4 8.6 1.2 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 DUF966 PF06136.13 EGD91474.1 - 0.89 9.2 14.7 1.1 8.9 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TSC22 PF01166.18 EGD91474.1 - 3 8.2 6.2 0.29 11.5 0.7 2.2 2 1 0 2 2 2 0 TSC-22/dip/bun family SOGA PF11365.8 EGD91474.1 - 3.1 9.0 10.6 0.085 14.0 2.9 2.3 3 0 0 3 3 3 0 Protein SOGA DUF4094 PF13334.6 EGD91474.1 - 8.7 6.8 9.2 25 5.4 9.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) ALIX_LYPXL_bnd PF13949.6 EGD91475.1 - 2.4e-88 296.2 11.7 6e-88 294.9 11.7 1.7 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV BRO1 PF03097.18 EGD91475.1 - 2.4e-68 230.7 0.2 1.1e-66 225.2 0.0 2.5 2 0 0 2 2 2 2 BRO1-like domain Cellulase-like PF12876.7 EGD91475.1 - 0.0047 16.3 0.7 0.054 12.9 0.1 2.1 2 0 0 2 2 2 1 Sugar-binding cellulase-like YebO PF13974.6 EGD91475.1 - 3.9 7.6 5.0 2.6 8.2 0.6 2.8 2 0 0 2 2 2 0 YebO-like protein bZIP_2 PF07716.15 EGD91476.1 - 4.1e-13 49.2 12.1 7.4e-13 48.4 12.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EGD91476.1 - 2.1e-05 24.5 10.9 3.7e-05 23.7 10.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor TFIIA PF03153.13 EGD91476.1 - 0.0016 18.5 22.3 0.0023 18.0 22.3 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1387 PF07139.11 EGD91476.1 - 0.043 13.6 13.3 0.069 12.9 13.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TSC22 PF01166.18 EGD91476.1 - 0.1 13.0 0.5 0.4 11.0 0.5 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF966 PF06136.13 EGD91476.1 - 0.86 9.3 13.4 1.1 8.9 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CCDC106 PF15794.5 EGD91476.1 - 2.4 7.8 16.4 2.4 7.8 1.1 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 DUF4094 PF13334.6 EGD91476.1 - 5.5 7.5 7.4 1.2 9.5 3.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) CENP-N PF05238.13 EGD91478.1 - 7.7e-121 404.3 4.4 1.9e-120 403.0 4.4 1.5 1 1 0 1 1 1 1 Kinetochore protein CHL4 like zf-ANAPC11 PF12861.7 EGD91479.2 - 7.5e-07 29.1 5.5 7e-06 26.0 1.9 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EGD91479.2 - 1.4e-06 28.5 6.2 1.4e-06 28.5 6.2 1.9 2 1 0 2 2 2 1 Ring finger domain SWIM PF04434.17 EGD91479.2 - 9.8e-06 25.1 0.6 1.7e-05 24.3 0.6 1.4 1 0 0 1 1 1 1 SWIM zinc finger FANCL_C PF11793.8 EGD91479.2 - 0.00098 19.3 7.4 0.0039 17.3 4.8 2.4 2 0 0 2 2 2 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 EGD91479.2 - 0.0015 18.4 1.5 0.0015 18.4 1.5 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 EGD91479.2 - 0.0058 16.4 6.4 0.012 15.4 6.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.29 EGD91479.2 - 0.012 15.5 7.1 0.023 14.6 7.1 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 EGD91479.2 - 0.029 14.5 8.7 0.058 13.5 8.7 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 EGD91479.2 - 0.99 9.3 7.8 0.23 11.4 4.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 EGD91479.2 - 1.2 9.1 7.2 0.39 10.6 2.9 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.7 EGD91479.2 - 1.2 9.5 11.1 0.13 12.6 5.9 2.1 2 1 0 2 2 2 0 RING-H2 zinc finger domain SCRL PF06876.12 EGD91479.2 - 2.3 8.4 8.3 0.6 10.3 1.1 2.3 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein DUF974 PF06159.13 EGD91480.1 - 2e-78 263.6 0.0 2.4e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.21 EGD91483.1 - 8.2e-56 188.9 0.1 1.7e-55 187.9 0.1 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EGD91483.1 - 1.6e-15 57.6 0.4 8.1e-15 55.3 0.0 2.5 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 EGD91483.1 - 3.2e-14 52.6 0.7 7.3e-14 51.5 0.7 1.7 1 0 0 1 1 1 1 dDENN domain C1_2 PF03107.16 EGD91483.1 - 1.5e-06 28.4 4.6 3.2e-06 27.3 4.6 1.6 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 EGD91483.1 - 0.005 16.7 5.8 0.01 15.7 5.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 EGD91483.1 - 0.14 12.2 5.9 0.31 11.2 5.9 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 EGD91483.1 - 2.6 7.8 7.6 4.6 6.9 7.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 EGD91483.1 - 3 7.8 8.7 2.2 8.2 6.6 1.9 1 1 1 2 2 2 0 PHD-finger zf-HIT PF04438.16 EGD91483.1 - 7.9 6.4 5.5 18 5.3 5.5 1.6 1 1 0 1 1 1 0 HIT zinc finger RTA1 PF04479.13 EGD91484.2 - 8.9e-33 113.6 5.6 1.1e-32 113.4 5.6 1.1 1 0 0 1 1 1 1 RTA1 like protein SLAC1 PF03595.17 EGD91484.2 - 0.00048 19.5 1.0 0.00055 19.3 1.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel GCSF PF16647.5 EGD91486.1 - 0.12 12.2 0.5 12 5.7 0.1 2.2 2 0 0 2 2 2 0 Granulocyte colony-stimulating factor Fungal_trans_2 PF11951.8 EGD91487.2 - 0.0014 17.6 1.1 0.0014 17.6 1.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain SLATT_fungal PF18142.1 EGD91488.1 - 5e-35 120.1 0.0 6.9e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain MutL_C PF08676.11 EGD91490.2 - 2.1e-10 40.5 0.0 1.1e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain RasGEF PF00617.19 EGD91491.2 - 1.2e-51 175.4 0.8 2.4e-51 174.4 0.8 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGD91491.2 - 1.8e-14 53.9 0.0 6e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 EGD91491.2 - 7.6e-07 28.9 0.1 2.1e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EGD91491.2 - 2.7e-05 23.7 0.0 7e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain GHMP_kinases_N PF00288.26 EGD91494.1 - 1.3e-11 44.6 0.1 3.2e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGD91494.1 - 7.2e-05 23.1 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Swm2 PF17083.5 EGD91497.2 - 0.029 14.4 0.1 0.061 13.3 0.1 1.5 1 0 0 1 1 1 0 Nucleolar protein Swm2 CAF1A PF12253.8 EGD91498.2 - 1.1e-22 80.0 4.6 2.8e-22 78.7 4.6 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A Methyltransf_23 PF13489.6 EGD91500.2 - 2.1e-15 57.0 0.0 8.1e-15 55.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD91500.2 - 0.00017 22.3 0.1 0.0055 17.4 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD91500.2 - 0.002 18.7 0.0 0.0038 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD91500.2 - 0.0082 16.9 0.0 0.02 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD91500.2 - 0.052 13.3 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CoA_transf_3 PF02515.17 EGD91503.1 - 4.8e-70 236.5 0.0 5.8e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DNA_ligase_OB_2 PF14743.6 EGD91503.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 DNA ligase OB-like domain adh_short_C2 PF13561.6 EGD91505.1 - 5.9e-57 192.9 0.1 7.4e-57 192.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD91505.1 - 1.5e-46 158.3 0.1 2.2e-46 157.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD91505.1 - 1.6e-11 44.5 0.6 2.5e-11 43.8 0.6 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EGD91505.1 - 0.0093 15.0 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGD91505.1 - 0.054 12.9 0.1 0.11 12.0 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HATPase_c PF02518.26 EGD91505.1 - 0.056 14.0 0.0 0.14 12.7 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CcmE PF03100.15 EGD91505.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 CcmE YjeF_N PF03853.15 EGD91505.1 - 0.081 12.8 0.0 0.4 10.6 0.0 2.0 1 1 1 2 2 2 0 YjeF-related protein N-terminus GDP_Man_Dehyd PF16363.5 EGD91505.1 - 0.13 11.7 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Peptidase_S64 PF08192.11 EGD91506.2 - 0.055 12.0 0.1 0.45 8.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S64 Peptidase_S3 PF00944.19 EGD91506.2 - 0.09 12.6 0.1 3.5 7.4 0.1 2.2 2 0 0 2 2 2 0 Alphavirus core protein Glyco_hydro_18 PF00704.28 EGD91508.2 - 1.9e-15 57.4 0.0 2.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PhoD PF09423.10 EGD91509.2 - 1.6e-38 132.7 0.0 5.9e-38 130.8 0.0 1.8 1 1 0 1 1 1 1 PhoD-like phosphatase SRP54 PF00448.22 EGD91510.1 - 3.1e-74 248.9 1.8 6.2e-74 247.9 1.8 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EGD91510.1 - 2.6e-28 98.5 0.1 2.6e-28 98.5 0.1 4.3 2 2 2 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 EGD91510.1 - 6.6e-20 71.1 0.4 1.6e-19 69.9 0.4 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EGD91510.1 - 7.1e-07 29.0 0.6 2.8e-06 27.0 0.5 2.1 2 1 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGD91510.1 - 2.3e-06 27.8 0.0 6.3e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGD91510.1 - 6.4e-05 23.4 0.1 6.4e-05 23.4 0.1 2.3 3 0 0 3 3 1 1 AAA domain Zeta_toxin PF06414.12 EGD91510.1 - 6.7e-05 22.2 0.1 0.00013 21.3 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 EGD91510.1 - 0.00033 19.7 1.2 0.0032 16.5 0.0 2.7 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EGD91510.1 - 0.00043 20.7 0.0 0.0013 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 EGD91510.1 - 0.00067 19.5 0.8 0.024 14.4 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein 6PF2K PF01591.18 EGD91510.1 - 0.002 17.5 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase APS_kinase PF01583.20 EGD91510.1 - 0.0024 17.8 0.1 0.0052 16.7 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ResIII PF04851.15 EGD91510.1 - 0.0032 17.5 1.3 0.016 15.2 1.3 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGD91510.1 - 0.005 16.6 0.3 0.005 16.6 0.3 2.1 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.10 EGD91510.1 - 0.0071 15.8 2.2 2.4 7.5 1.8 3.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit CbiA PF01656.23 EGD91510.1 - 0.0074 16.3 0.0 0.014 15.5 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 EGD91510.1 - 0.0099 16.2 0.0 0.044 14.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGD91510.1 - 0.01 15.5 0.2 0.038 13.7 0.2 1.9 1 0 0 1 1 1 0 Thymidylate kinase Methyltransf_25 PF13649.6 EGD91510.1 - 0.014 16.1 0.5 1.2 9.9 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain AAA_18 PF13238.6 EGD91510.1 - 0.015 15.8 0.1 0.042 14.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.23 EGD91510.1 - 0.02 15.0 0.2 0.088 12.9 0.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EGD91510.1 - 0.031 14.0 0.1 0.078 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGD91510.1 - 0.042 14.1 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EGD91510.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_19 PF13245.6 EGD91510.1 - 0.044 14.1 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EGD91510.1 - 0.054 13.4 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 EGD91510.1 - 0.087 12.7 0.9 0.73 9.7 1.0 2.3 1 1 0 1 1 1 0 AAA domain VirE PF05272.11 EGD91510.1 - 0.1 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Virulence-associated protein E ABC_tran PF00005.27 EGD91510.1 - 0.13 12.8 1.0 0.31 11.5 0.1 2.1 2 1 0 2 2 2 0 ABC transporter Rrp15p PF07890.12 EGD91511.1 - 1.2e-38 132.5 8.5 1.2e-38 132.5 8.5 1.9 2 1 0 2 2 2 1 Rrp15p RRN3 PF05327.11 EGD91511.1 - 0.12 10.9 5.0 0.17 10.4 5.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FliL PF03748.14 EGD91511.1 - 2.4 8.8 5.6 13 6.5 0.0 3.0 2 1 1 3 3 3 0 Flagellar basal body-associated protein FliL Fer2 PF00111.27 EGD91512.1 - 2.8e-14 52.8 0.5 4.2e-14 52.2 0.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.27 EGD91513.1 - 1.2e-10 41.1 0.6 0.013 15.4 0.0 4.8 4 1 0 4 4 4 3 Mitochondrial carrier protein DUF3175 PF11373.8 EGD91513.1 - 0.1 12.8 0.2 0.37 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3175) Hap4_Hap_bind PF10297.9 EGD91514.1 - 1e-07 31.8 6.9 2.3e-07 30.7 6.9 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EGD91514.1 - 1.5e-07 31.4 12.2 4.3e-07 29.9 12.2 1.8 1 0 0 1 1 1 1 bZIP transcription factor DUF812 PF05667.11 EGD91514.1 - 0.0069 15.3 6.2 0.0099 14.8 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) dsrm PF00035.26 EGD91514.1 - 0.078 13.7 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif PSI_PsaF PF02507.15 EGD91514.1 - 0.23 11.3 1.2 0.41 10.5 1.2 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III SlyX PF04102.12 EGD91514.1 - 0.7 10.5 8.4 1.9 9.2 6.9 2.4 1 1 1 2 2 2 0 SlyX bZIP_2 PF07716.15 EGD91514.1 - 1.9 8.6 20.8 15 5.7 20.8 2.4 1 1 0 1 1 1 0 Basic region leucine zipper Golgin_A5 PF09787.9 EGD91514.1 - 3.9 6.8 13.7 3.9 6.8 12.2 1.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 V_ATPase_I PF01496.19 EGD91514.1 - 5.2 4.9 6.0 6.4 4.5 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 EGD91514.1 - 7.4 5.8 7.4 15 4.8 7.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_Maf PF03131.17 EGD91514.1 - 8.8 6.9 16.6 1.4 9.5 12.3 1.9 2 0 0 2 2 1 0 bZIP Maf transcription factor Methyltransf_24 PF13578.6 EGD91515.1 - 3.2e-12 47.4 0.0 4.8e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EGD91515.1 - 0.0013 17.9 0.1 0.0072 15.5 0.1 1.9 1 1 0 1 1 1 1 O-methyltransferase Ribosomal_L19 PF01245.20 EGD91516.1 - 1.9e-11 43.9 0.1 4.3e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L19 AMP-binding PF00501.28 EGD91518.2 - 1.3e-13 50.4 0.0 3.5e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NPCC PF08058.11 EGD91519.1 - 2.8e-24 85.6 0.0 4.3e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex component HTH_21 PF13276.6 EGD91519.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 HTH-like domain Glycogen_syn PF05693.13 EGD91520.2 - 1.2e-303 1008.6 0.0 1.5e-303 1008.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 EGD91520.2 - 9.1e-06 25.8 0.2 2e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EGD91520.2 - 1.1e-05 25.1 0.0 0.0042 16.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGD91520.2 - 1.4e-05 25.6 0.0 0.021 15.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGD91520.2 - 4.1e-05 24.1 0.0 0.00011 22.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 EGD91520.2 - 7.3e-05 22.6 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain polyprenyl_synt PF00348.17 EGD91521.1 - 1.2e-90 303.0 0.0 1.5e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase TPR_1 PF00515.28 EGD91522.2 - 5e-23 79.9 4.9 6.7e-05 22.5 0.0 5.7 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGD91522.2 - 2e-21 74.4 6.2 6.5e-06 25.9 0.0 6.0 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGD91522.2 - 7.3e-16 56.9 12.1 0.022 14.8 2.8 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGD91522.2 - 1.4e-12 47.3 13.6 0.0024 18.5 0.0 6.0 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGD91522.2 - 2e-12 46.5 4.2 4e-07 29.6 0.3 4.7 3 2 2 5 5 5 4 TPR repeat TPR_16 PF13432.6 EGD91522.2 - 2.8e-10 40.7 13.7 6e-06 26.8 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGD91522.2 - 3.9e-10 40.1 6.0 0.023 15.2 0.4 5.0 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGD91522.2 - 3.8e-09 36.6 5.5 4.1e-05 23.6 0.4 3.4 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGD91522.2 - 7.9e-09 35.7 7.8 0.09 13.1 0.0 5.1 5 1 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGD91522.2 - 1.5e-07 31.5 5.7 0.032 14.4 0.3 3.7 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGD91522.2 - 7.6e-07 29.1 2.6 0.49 10.9 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGD91522.2 - 0.00011 22.5 22.7 2.4 9.0 0.1 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGD91522.2 - 0.00016 21.4 10.7 1.1 9.4 0.0 5.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGD91522.2 - 0.00017 20.9 2.9 0.0006 19.1 1.4 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGD91522.2 - 0.32 10.9 9.0 15 5.6 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 EGD91522.2 - 0.67 10.0 3.3 3 7.9 0.1 3.0 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) DNA_ligase_A_M PF01068.21 EGD91523.1 - 1.1e-21 77.5 0.0 1.8e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGD91523.1 - 1.5e-19 71.0 0.0 3.3e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 EGD91523.1 - 1.1e-05 25.7 0.0 4.5e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 RNA ligase DUF3449 PF11931.8 EGD91525.1 - 2.2e-76 255.7 0.3 2.2e-76 255.7 0.3 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EGD91525.1 - 4.7e-23 81.5 1.8 7.1e-23 80.9 0.6 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EGD91525.1 - 2.2e-11 43.4 0.2 4.7e-11 42.4 0.2 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 EGD91525.1 - 2.7e-09 37.1 3.9 1.2e-07 31.9 1.0 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGD91525.1 - 7.4e-08 32.5 1.0 7.4e-08 32.5 1.0 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGD91525.1 - 0.00033 20.9 0.1 0.017 15.5 0.0 2.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 EGD91525.1 - 0.053 13.4 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 EGD91525.1 - 0.082 13.8 1.4 5.3 8.2 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger PRP9_N PF16958.5 EGD91525.1 - 0.73 9.9 20.1 0.12 12.4 1.1 3.6 3 1 1 4 4 4 0 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2 PF00096.26 EGD91525.1 - 2.5 8.7 4.3 5.6 7.6 0.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.29 EGD91526.2 - 7.4e-42 143.1 0.1 1.3e-41 142.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD91526.2 - 1.5e-33 115.5 0.1 6.2e-33 113.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EGD91526.2 - 0.00066 19.4 0.0 0.00097 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGD91526.2 - 0.00068 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGD91526.2 - 0.0024 18.2 0.0 0.023 15.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 EGD91526.2 - 0.049 13.5 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 EGD91526.2 - 0.052 13.5 0.9 0.15 12.0 0.1 2.2 2 2 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 EGD91526.2 - 0.078 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 EGD91526.2 - 0.11 12.8 1.0 0.58 10.4 1.0 2.1 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 EGD91527.2 - 3.1e-25 87.9 8.1 5.5e-05 23.9 0.0 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD91527.2 - 1.9e-14 53.7 1.2 0.0019 18.4 0.0 5.4 2 1 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGD91527.2 - 3.5e-05 22.9 0.0 0.024 13.6 0.0 3.4 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGD91527.2 - 0.00045 20.1 0.2 15 5.7 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EGD91527.2 - 0.0012 18.8 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EGD91527.2 - 0.09 11.3 0.0 0.84 8.1 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain ATP-synt_ab PF00006.25 EGD91528.2 - 1.4e-96 322.3 0.0 2e-96 321.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EGD91528.2 - 2.4e-44 150.1 0.0 4.9e-44 149.1 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EGD91528.2 - 2.3e-14 53.7 3.6 4.6e-14 52.7 3.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Dynamin_M PF01031.20 EGD91529.1 - 1.3e-101 339.6 0.0 2.5e-101 338.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EGD91529.1 - 5.2e-57 192.6 0.2 9.8e-57 191.7 0.2 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EGD91529.1 - 8.7e-30 102.7 2.8 2.2e-29 101.4 2.8 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGD91529.1 - 6.3e-06 26.3 1.1 3.7e-05 23.8 1.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2738 PF10927.8 EGD91529.1 - 0.065 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) AAA_16 PF13191.6 EGD91529.1 - 0.075 13.4 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 EGD91529.1 - 0.24 11.1 3.2 2.1 8.0 0.4 2.5 2 1 0 2 2 2 0 AAA ATPase domain COesterase PF00135.28 EGD91530.1 - 2.8e-37 128.8 0.0 1.9e-28 99.6 0.0 2.5 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGD91530.1 - 6.4e-08 32.7 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2264 PF10022.9 EGD91530.1 - 0.0012 18.0 0.1 0.0019 17.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Abhydrolase_6 PF12697.7 EGD91530.1 - 0.0041 17.8 1.9 0.0041 17.8 1.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGD91530.1 - 0.0076 15.9 0.0 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.8 EGD91530.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 EGD91530.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Basic PF01586.16 EGD91531.1 - 0.044 14.9 0.0 0.068 14.4 0.0 1.3 1 0 0 1 1 1 0 Myogenic Basic domain DUF5549 PF17703.1 EGD91533.2 - 0.011 15.4 1.1 0.021 14.5 0.2 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5549) DUF4716 PF15837.5 EGD91533.2 - 0.083 13.0 0.1 0.19 11.8 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4716) Cytochrome-c551 PF10643.9 EGD91534.2 - 0.043 13.4 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 NmrA PF05368.13 EGD91536.2 - 0.0029 17.2 0.0 0.0036 16.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family WD40 PF00400.32 EGD91538.1 - 6.9e-19 67.8 16.2 3.8e-06 27.5 0.0 8.4 7 2 0 7 7 7 3 WD domain, G-beta repeat Peptidase_S8 PF00082.22 EGD91538.1 - 3.2e-18 66.0 0.0 5.2e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Subtilase family ANAPC4_WD40 PF12894.7 EGD91538.1 - 2.2e-15 56.7 0.1 0.048 13.9 0.1 6.9 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGD91538.1 - 3.8e-09 36.3 2.3 9.9 6.2 0.0 8.6 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat NACHT PF05729.12 EGD91538.1 - 7.1e-08 32.5 1.0 2.8e-06 27.4 0.2 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EGD91538.1 - 0.00013 22.4 0.0 0.00038 20.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Lactonase PF10282.9 EGD91538.1 - 0.00023 20.5 0.0 0.00069 19.0 0.0 1.8 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller KAP_NTPase PF07693.14 EGD91538.1 - 0.00042 19.7 0.0 0.00079 18.8 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain Nup160 PF11715.8 EGD91538.1 - 0.00053 18.8 0.0 0.63 8.6 0.1 3.2 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 EGD91538.1 - 0.0023 17.3 0.5 0.67 9.2 0.0 3.5 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 EGD91538.1 - 0.021 13.8 0.1 3.4 6.5 0.0 3.9 3 2 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 EGD91538.1 - 0.36 10.6 8.9 8.2 6.2 0.0 5.5 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Hce2 PF14856.6 EGD91540.1 - 1.3e-28 99.3 0.2 1.7e-28 98.9 0.2 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Glyco_transf_54 PF04666.13 EGD91541.1 - 2.2e-14 53.0 0.0 3.3e-10 39.3 0.0 3.0 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region MUG113 PF13455.6 EGD91542.1 - 4.7e-21 75.2 0.5 1e-20 74.1 0.5 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 EGD91542.1 - 2.4e-20 73.0 0.2 5.9e-20 71.7 0.2 1.7 1 0 0 1 1 1 1 T5orf172 domain Promethin PF16015.5 EGD91543.1 - 4.5e-27 94.1 17.5 6e-27 93.6 17.5 1.2 1 0 0 1 1 1 1 Promethin UL45 PF05473.12 EGD91543.1 - 0.11 12.1 1.9 0.18 11.4 1.9 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Spc42p PF11544.8 EGD91544.1 - 0.46 10.5 9.8 3.8 7.6 9.8 2.7 1 0 0 1 1 1 0 Spindle pole body component Spc42p Sas6_CC PF18594.1 EGD91544.1 - 2.7 7.9 9.4 0.11 12.3 0.5 3.2 3 0 0 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain SecY PF00344.20 EGD91545.2 - 3.6e-73 246.5 7.5 4.5e-73 246.2 7.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EGD91545.2 - 2.2e-17 62.6 0.3 6e-17 61.2 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p ArgJ PF01960.18 EGD91546.1 - 1.9e-149 497.5 0.1 2.2e-149 497.3 0.1 1.0 1 0 0 1 1 1 1 ArgJ family ORC2 PF04084.14 EGD91547.1 - 1.8e-117 392.0 0.0 2.2e-117 391.7 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.19 EGD91547.1 - 2.9 8.1 10.6 8.1 6.7 10.6 1.8 1 0 0 1 1 1 0 AT hook motif FUN14 PF04930.15 EGD91548.1 - 1.9e-07 31.4 1.2 4.9e-07 30.1 1.2 1.7 1 1 0 1 1 1 1 FUN14 family DUF3487 PF11990.8 EGD91548.1 - 0.25 11.3 1.5 0.58 10.1 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3487) SOR_SNZ PF01680.17 EGD91549.1 - 7e-108 359.1 4.7 1.2e-107 358.4 4.7 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EGD91549.1 - 1.1e-09 37.9 6.3 1.4e-07 31.1 0.1 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EGD91549.1 - 0.0019 17.4 0.6 0.32 10.0 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EGD91549.1 - 0.0023 17.5 0.2 0.032 13.7 0.0 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein TetR_C_27 PF17935.1 EGD91549.1 - 0.0041 17.2 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 EGD91549.1 - 0.0083 15.3 0.0 0.35 10.0 0.0 2.4 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.17 EGD91549.1 - 0.018 14.4 0.7 0.62 9.4 0.0 3.1 3 0 0 3 3 3 0 Thiamine monophosphate synthase NanE PF04131.14 EGD91549.1 - 0.02 14.1 0.9 0.26 10.5 0.0 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.24 EGD91549.1 - 0.052 13.1 0.1 0.4 10.2 0.0 2.1 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Importin_rep_3 PF18806.1 EGD91551.2 - 0.00028 20.9 0.0 0.094 12.8 0.0 2.8 2 0 0 2 2 2 2 Importin 13 repeat U3snoRNP10 PF12397.8 EGD91551.2 - 0.095 13.0 0.1 0.85 10.0 0.1 2.4 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 MEF2_binding PF09047.10 EGD91551.2 - 0.89 9.5 2.6 0.72 9.7 0.3 2.0 2 0 0 2 2 2 0 MEF2 binding Creatinase_N_2 PF16189.5 EGD91552.2 - 3.5e-53 180.0 0.0 9.1e-52 175.4 0.1 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EGD91552.2 - 2.2e-32 112.4 0.0 3.8e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EGD91552.2 - 1.2e-19 71.2 0.0 3.7e-16 60.0 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Pga1 PF10333.9 EGD91553.1 - 0.0024 17.8 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator LapA_dom PF06305.11 EGD91553.1 - 0.2 11.5 1.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Tubulin PF00091.25 EGD91554.1 - 6.8e-65 219.0 0.0 1.1e-64 218.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGD91554.1 - 2e-47 160.5 0.1 3.7e-47 159.6 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGD91554.1 - 0.0017 18.1 0.0 0.005 16.5 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain EF-hand_4 PF12763.7 EGD91555.1 - 9.5e-39 131.5 0.0 2e-15 56.6 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EGD91555.1 - 9.2e-09 35.6 0.0 4e-05 24.0 0.0 4.2 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EGD91555.1 - 8.5e-07 28.1 1.3 0.022 14.3 0.0 5.9 7 0 0 7 7 7 1 EF hand UBA PF00627.31 EGD91555.1 - 2.3e-05 24.2 0.1 4.2e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.6 EGD91555.1 - 3.3e-05 23.4 1.0 9.2 6.5 0.0 6.3 6 0 0 6 6 6 0 EF-hand domain DUF812 PF05667.11 EGD91555.1 - 0.0029 16.6 14.8 0.0061 15.5 14.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF812) EF-hand_8 PF13833.6 EGD91555.1 - 0.0032 17.3 0.2 0.091 12.6 0.0 3.5 4 0 0 4 4 4 1 EF-hand domain pair BicD PF09730.9 EGD91555.1 - 0.0064 15.0 26.9 0.054 11.9 26.3 2.0 1 1 0 1 1 1 1 Microtubule-associated protein Bicaudal-D GAS PF13851.6 EGD91555.1 - 0.0079 15.6 32.0 0.048 13.0 17.9 2.7 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 EGD91555.1 - 0.27 10.5 35.1 0.079 12.3 13.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 EGD91555.1 - 0.73 10.1 30.2 0.17 12.1 4.9 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FPP PF05911.11 EGD91555.1 - 0.87 7.7 26.4 1.3 7.1 26.4 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil CENP-F_leu_zip PF10473.9 EGD91555.1 - 1.9 8.5 32.0 0.29 11.2 12.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFT57 PF10498.9 EGD91555.1 - 2.2 7.1 21.6 15 4.4 21.5 2.0 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 ATG16 PF08614.11 EGD91555.1 - 3.4 7.8 38.3 5.1 7.3 15.0 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Cep57_MT_bd PF06657.13 EGD91555.1 - 4.1 7.9 12.8 0.1 13.1 3.7 2.8 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Spc7 PF08317.11 EGD91555.1 - 5.8 5.7 33.8 1.2 7.9 10.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EGD91555.1 - 7.4 6.0 17.9 14 5.2 17.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 EGD91555.1 - 8.5 6.6 22.2 0.039 14.1 8.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ERM PF00769.19 EGD91555.1 - 8.7 6.1 35.7 7.6 6.3 31.1 2.5 2 1 0 2 2 2 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 EGD91555.1 - 9.5 6.3 38.9 3 7.9 16.4 2.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein MARVEL PF01284.23 EGD91556.1 - 3e-17 63.0 20.8 3.7e-17 62.7 20.8 1.0 1 0 0 1 1 1 1 Membrane-associating domain Cys_Met_Meta_PP PF01053.20 EGD91558.1 - 3.6e-146 486.6 0.0 4.1e-146 486.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGD91558.1 - 9.3e-13 48.2 0.2 1.7e-12 47.3 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGD91558.1 - 4.5e-09 35.9 0.1 7.4e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGD91558.1 - 1.5e-07 30.8 0.2 2.7e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGD91558.1 - 0.00075 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Asparaginase_C PF17763.1 EGD91558.1 - 0.021 15.0 0.1 0.092 13.0 0.0 2.1 3 0 0 3 3 3 0 Glutaminase/Asparaginase C-terminal domain SepSecS PF05889.13 EGD91558.1 - 0.035 12.8 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS AMP-binding PF00501.28 EGD91559.1 - 3.5e-84 282.9 0.0 4.3e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2012 PF09430.10 EGD91560.1 - 1.2e-22 80.3 0.0 1.7e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 EGD91560.1 - 0.057 13.0 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Suppressor of PMA 1-7 protein LCCL PF03815.19 EGD91561.1 - 5.3e-20 71.3 0.1 8.1e-20 70.7 0.1 1.3 1 0 0 1 1 1 1 LCCL domain DUF3328 PF11807.8 EGD91564.1 - 4.8e-47 160.6 0.4 6e-47 160.3 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Dexa_ind PF15198.6 EGD91564.1 - 0.14 12.3 0.9 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Dexamethasone-induced Sigma_reg_N PF13800.6 EGD91564.1 - 0.14 12.4 0.4 0.25 11.6 0.4 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Ank_4 PF13637.6 EGD91565.2 - 1.4e-27 95.7 0.4 9.3e-12 45.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGD91565.2 - 1.1e-22 80.4 0.1 7.3e-16 58.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGD91565.2 - 3e-19 68.8 0.6 4e-07 30.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGD91565.2 - 8.6e-18 63.9 0.3 3.6e-05 24.0 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EGD91565.2 - 3.6e-16 57.6 0.0 1.6e-05 24.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.21 EGD91565.2 - 0.0011 19.1 8.2 0.0019 18.3 8.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EGD91565.2 - 0.0084 16.6 6.6 0.014 15.9 6.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor VWA_3_C PF18571.1 EGD91565.2 - 0.08 12.8 0.3 3.4 7.6 0.1 2.5 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain PTR2 PF00854.21 EGD91566.1 - 2.3e-79 267.1 8.1 3.1e-79 266.7 8.1 1.2 1 0 0 1 1 1 1 POT family Methyltransf_32 PF13679.6 EGD91567.2 - 5.4e-20 72.0 2.8 3.1e-19 69.5 2.8 2.0 1 1 0 1 1 1 1 Methyltransferase domain Syntaxin-6_N PF09177.11 EGD91568.1 - 7.3e-24 84.2 1.1 2.2e-23 82.7 0.1 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EGD91568.1 - 0.0026 17.7 1.4 0.0059 16.6 1.4 1.6 1 0 0 1 1 1 1 SNARE domain APG17 PF04108.12 EGD91568.1 - 0.0033 16.6 2.9 0.14 11.3 0.2 2.2 2 0 0 2 2 2 2 Autophagy protein Apg17 DUF3618 PF12277.8 EGD91568.1 - 0.0096 16.2 8.1 1.3 9.4 0.2 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3618) DUF4795 PF16043.5 EGD91568.1 - 0.035 13.7 0.9 0.92 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) HMMR_N PF15905.5 EGD91568.1 - 0.038 13.5 0.1 0.038 13.5 0.1 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Vps51 PF08700.11 EGD91568.1 - 0.063 13.4 3.1 10 6.3 0.0 3.4 3 1 0 3 3 3 0 Vps51/Vps67 SPX PF03105.19 EGD91568.1 - 0.16 11.9 1.2 0.19 11.6 1.2 1.1 1 0 0 1 1 1 0 SPX domain Laminin_II PF06009.12 EGD91568.1 - 0.18 11.8 1.0 4.5 7.3 0.1 2.4 2 1 0 2 2 2 0 Laminin Domain II DUF2312 PF10073.9 EGD91568.1 - 0.3 10.8 4.1 3.3 7.4 0.7 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF4726 PF15855.5 EGD91568.1 - 0.32 11.3 0.1 0.32 11.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) Cnn_1N PF07989.11 EGD91568.1 - 0.48 10.6 8.0 14 5.9 1.5 3.5 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 GCIP PF13324.6 EGD91568.1 - 0.89 9.1 6.3 0.52 9.9 2.8 2.1 2 1 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF883 PF05957.13 EGD91568.1 - 0.98 10.1 6.3 22 5.7 0.0 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EGD91568.1 - 1.5 9.4 3.5 6.7 7.3 0.5 2.6 2 1 0 2 2 2 0 YtxH-like protein NAP PF00956.18 EGD91569.1 - 9.5e-19 67.6 6.4 9.5e-19 67.6 6.4 2.6 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) NmrA PF05368.13 EGD91570.1 - 2.4e-68 230.2 0.0 2.9e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family DUF1876 PF08962.11 EGD91570.1 - 0.23 11.5 0.2 0.23 11.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) Asparaginase PF00710.20 EGD91571.1 - 8.7e-57 191.8 0.0 1.2e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EGD91571.1 - 7.7e-30 103.5 0.3 3.6e-29 101.3 0.3 2.0 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 EGD91571.1 - 3.2e-17 62.9 1.2 1.3e-10 41.7 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGD91571.1 - 1.6e-10 40.9 5.2 2.3e-06 27.8 0.4 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGD91571.1 - 5.3e-09 35.6 1.3 0.00032 20.9 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGD91571.1 - 3.1e-08 33.7 0.1 1.1e-07 32.0 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGD91571.1 - 1.5e-07 31.9 0.1 5.6e-05 23.6 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) MTTB PF06253.11 EGD91571.1 - 0.006 14.6 0.1 0.0092 14.0 0.1 1.2 1 0 0 1 1 1 1 Trimethylamine methyltransferase (MTTB) DUF1996 PF09362.10 EGD91577.1 - 4.5e-84 282.1 0.2 6.9e-84 281.5 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) AdoMet_MTase PF07757.13 EGD91577.1 - 0.016 15.5 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase adh_short PF00106.25 EGD91578.2 - 1.3e-21 77.0 0.1 1.5e-21 76.8 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD91578.2 - 2e-15 57.0 0.0 2.5e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD91578.2 - 0.0092 15.9 1.1 0.03 14.2 1.1 1.7 1 1 0 1 1 1 1 KR domain HI0933_like PF03486.14 EGD91578.2 - 0.017 13.8 0.5 0.02 13.6 0.5 1.1 1 0 0 1 1 1 0 HI0933-like protein Dak1 PF02733.17 EGD91578.2 - 0.075 11.9 2.2 0.53 9.1 0.7 2.0 1 1 1 2 2 2 0 Dak1 domain Epimerase PF01370.21 EGD91578.2 - 0.11 11.9 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AA_permease_2 PF13520.6 EGD91579.2 - 9.8e-42 143.2 49.5 1.2e-41 142.9 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGD91579.2 - 9.8e-17 60.7 40.1 1.3e-16 60.2 40.1 1.0 1 0 0 1 1 1 1 Amino acid permease ELO PF01151.18 EGD91581.1 - 5.7e-63 212.8 19.9 6.8e-63 212.5 19.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family COX5A PF02284.16 EGD91582.2 - 2e-38 130.5 0.8 2.7e-38 130.1 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF4972 PF16342.5 EGD91582.2 - 0.11 12.2 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) WD40_4 PF16300.5 EGD91582.2 - 0.11 12.4 0.0 9.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Type of WD40 repeat Acetyltransf_8 PF13523.6 EGD91584.1 - 1.2e-45 154.8 0.7 1.7e-45 154.3 0.7 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CLASP_N PF12348.8 EGD91585.1 - 1.1e-149 496.1 2.8 5.2e-91 304.2 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal Cnd1 PF12717.7 EGD91585.1 - 1.7e-06 28.2 0.1 0.042 13.9 0.0 4.5 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGD91585.1 - 2.1e-05 24.4 0.6 5.4 7.6 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat BSP PF04450.12 EGD91586.2 - 1.6e-64 217.5 0.0 1.9e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Ribonucleas_3_3 PF14622.6 EGD91588.1 - 7.7e-07 29.3 0.0 0.004 17.3 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGD91588.1 - 0.00012 22.6 0.0 0.00023 21.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain PfkB PF00294.24 EGD91590.2 - 2.6e-11 43.4 0.0 5e-11 42.5 0.0 1.4 2 0 0 2 2 2 1 pfkB family carbohydrate kinase CAP_N PF01213.19 EGD91591.1 - 2.9e-112 375.3 0.5 3.9e-112 374.8 0.0 1.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EGD91591.1 - 2.1e-54 183.4 1.4 2.8e-54 183.0 1.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EGD91591.1 - 0.1 12.3 3.1 1.8 8.3 3.0 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C Ribosomal_60s PF00428.19 EGD91591.1 - 2.9 8.6 7.6 0.3 11.7 1.4 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF4210 PF13915.6 EGD91592.1 - 2e-33 114.8 0.1 5.5e-33 113.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 EGD91592.1 - 8.9e-22 77.0 0.2 2.3e-21 75.7 0.2 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.11 EGD91593.1 - 0.061 13.4 19.0 4.6 7.3 19.0 2.4 1 1 0 1 1 1 0 rRNA processing GCP_C_terminal PF04130.13 EGD91594.2 - 3.1e-65 220.7 0.0 4.3e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGD91594.2 - 5e-32 111.8 0.0 1.2e-30 107.2 0.0 2.7 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF2310 PF10071.9 EGD91594.2 - 0.02 14.2 0.1 0.035 13.4 0.1 1.3 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Eaf7 PF07904.13 EGD91595.1 - 3.1e-28 98.2 0.0 6.4e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Iso_dh PF00180.20 EGD91596.1 - 1.9e-101 339.7 0.0 2.4e-101 339.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 EGD91596.1 - 0.0062 16.3 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 Bacteriophage protein GP30.3 Sec5 PF15469.6 EGD91597.1 - 4.5e-36 124.4 0.0 1.2e-35 123.0 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 EGD91597.1 - 2.8e-05 24.1 0.7 0.0001 22.3 0.7 2.0 1 0 0 1 1 1 1 Vps51/Vps67 GTP-bdg_M PF16360.5 EGD91597.1 - 0.0048 17.5 0.7 0.52 10.9 0.2 3.6 3 0 0 3 3 3 1 GTP-binding GTPase Middle Region RINT1_TIP1 PF04437.13 EGD91597.1 - 0.065 12.1 0.2 0.14 11.0 0.2 1.5 1 0 0 1 1 1 0 RINT-1 / TIP-1 family COG2 PF06148.11 EGD91597.1 - 0.077 13.1 0.3 0.3 11.2 0.3 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF802 PF05650.11 EGD91597.1 - 0.72 10.4 4.0 0.31 11.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF802) Mo-co_dimer PF03404.16 EGD91598.1 - 1.9e-58 196.4 0.5 3.6e-58 195.5 0.5 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EGD91598.1 - 2.9e-54 183.3 0.0 4.9e-54 182.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_1 PF00175.21 EGD91598.1 - 3.3e-27 95.3 0.0 2.2e-26 92.6 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EGD91598.1 - 1.3e-17 63.7 0.0 2.9e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 EGD91598.1 - 5.9e-17 61.9 0.0 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGD91598.1 - 0.0044 17.2 0.1 0.046 13.9 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain LPMO_10 PF03067.15 EGD91599.1 - 0.0054 17.4 0.1 0.018 15.7 0.1 1.8 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading PI-PLC-X PF00388.19 EGD91602.2 - 2.5e-58 195.8 0.0 6.1e-58 194.5 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGD91602.2 - 1.6e-42 144.5 0.1 3.3e-42 143.5 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGD91602.2 - 4.1e-05 23.8 0.0 0.0003 21.0 0.0 2.3 1 1 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 EGD91602.2 - 0.0025 18.3 0.9 0.007 16.8 0.9 1.8 1 1 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.17 EGD91602.2 - 0.14 11.8 0.0 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family AhpC-TSA_2 PF13911.6 EGD91603.1 - 1.3e-11 44.6 0.0 2.2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGD91603.1 - 0.00051 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family AAA_12 PF13087.6 EGD91605.2 - 3.6e-58 196.5 0.0 5.7e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGD91605.2 - 3.1e-52 178.0 5.3 3.8e-30 105.6 0.3 2.2 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EGD91605.2 - 1.5e-33 114.9 0.0 3.1e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) UPF1_Zn_bind PF09416.10 EGD91605.2 - 2.9e-16 59.8 3.4 3e-15 56.5 0.3 2.4 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_30 PF13604.6 EGD91605.2 - 2.6e-12 46.8 0.2 2.4e-11 43.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGD91605.2 - 4e-10 40.2 0.1 2.1e-09 37.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 EGD91605.2 - 2.7e-06 27.5 0.0 5.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EGD91605.2 - 0.00014 21.8 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 EGD91605.2 - 0.00029 20.7 0.1 0.96 9.1 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EGD91605.2 - 0.0013 18.0 0.7 0.027 13.7 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 EGD91605.2 - 0.017 14.6 0.0 0.24 10.9 0.1 2.3 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 EGD91605.2 - 0.017 14.3 0.0 4.8 6.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase DEAD PF00270.29 EGD91605.2 - 0.021 14.6 0.4 0.046 13.5 0.2 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 EGD91605.2 - 0.022 15.0 0.0 0.067 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGD91605.2 - 0.034 13.6 0.0 0.082 12.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein DUF4123 PF13503.6 EGD91605.2 - 0.047 14.1 0.4 0.72 10.3 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4123) AAA_10 PF12846.7 EGD91605.2 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 EGD91605.2 - 0.12 12.8 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 EGD91605.2 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 EGD91605.2 - 0.16 11.3 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 KaiC PTCB-BRCT PF12738.7 EGD91606.1 - 3.8e-07 30.0 0.1 8.3e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EGD91606.1 - 8.8e-06 26.0 0.0 1.9e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGD91606.1 - 1.1e-05 25.7 0.0 2.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain WGR PF05406.15 EGD91606.1 - 0.0008 19.4 0.0 0.0024 17.9 0.0 1.8 1 0 0 1 1 1 1 WGR domain IGPS PF00218.21 EGD91607.1 - 1.6e-94 315.9 0.0 6.1e-94 313.9 0.0 1.9 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EGD91607.1 - 2.7e-52 177.4 0.1 4.5e-47 160.4 0.0 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EGD91607.1 - 1.1e-47 162.3 0.0 2.2e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGD91607.1 - 0.00045 20.0 0.3 0.0028 17.4 0.3 2.2 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 EGD91607.1 - 0.0066 16.2 0.2 0.36 10.6 0.0 2.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 EGD91607.1 - 0.037 13.5 0.1 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 EGD91607.1 - 0.12 11.5 0.3 0.44 9.7 0.0 2.0 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Nup188_C PF18378.1 EGD91608.2 - 1.9e-138 461.3 0.0 2.8e-138 460.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 EGD91608.2 - 2.4e-68 231.0 0.0 3.8e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Acetyltransf_1 PF00583.25 EGD91612.1 - 1.7e-05 25.0 0.0 4.6e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGD91612.1 - 7.2e-05 22.7 0.0 0.0029 17.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGD91612.1 - 0.0034 17.8 0.0 0.0066 16.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Use1 PF09753.9 EGD91613.1 - 8.3e-12 45.4 0.0 8.3e-12 45.4 0.0 2.3 1 1 1 2 2 2 1 Membrane fusion protein Use1 DUF5538 PF17692.1 EGD91613.1 - 0.0068 16.5 1.1 0.016 15.2 1.1 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5538) HR1 PF02185.16 EGD91613.1 - 2.3 8.4 10.4 0.15 12.2 3.8 2.4 2 1 0 2 2 2 0 Hr1 repeat G-alpha PF00503.20 EGD91614.1 - 2.4e-123 411.8 1.7 2.8e-123 411.6 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGD91614.1 - 1.7e-15 56.9 1.1 2.5e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 EGD91614.1 - 6.3e-05 22.7 0.0 0.00027 20.7 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 EGD91614.1 - 0.0012 18.3 3.0 0.053 12.9 0.0 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGD91614.1 - 0.014 15.6 0.2 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGD91614.1 - 0.019 14.7 0.1 0.051 13.3 0.1 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EGD91614.1 - 0.026 13.7 0.1 0.042 13.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain GTP_EFTU PF00009.27 EGD91614.1 - 0.061 12.8 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.23 EGD91614.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 EGD91614.1 - 0.1 12.0 0.0 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EGD91614.1 - 0.14 12.2 0.0 10 6.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase CH PF00307.31 EGD91616.2 - 1.5e-29 102.3 0.0 7.9e-24 83.9 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGD91616.2 - 1.2e-07 31.5 0.0 3.4e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain EF-hand_6 PF13405.6 EGD91616.2 - 0.0013 18.4 0.0 0.0063 16.4 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain Spectrin PF00435.21 EGD91616.2 - 0.007 16.8 5.3 0.55 10.7 0.0 2.7 1 1 0 2 2 2 1 Spectrin repeat EF-hand_8 PF13833.6 EGD91616.2 - 0.0074 16.1 0.3 0.037 13.9 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGD91616.2 - 0.013 15.0 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 0 EF hand SKA1 PF07160.12 EGD91616.2 - 0.089 12.6 1.5 0.15 11.9 0.9 1.6 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 EF-hand_7 PF13499.6 EGD91616.2 - 0.21 12.0 2.5 0.74 10.3 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain pair Hom_end_hint PF05203.16 EGD91616.2 - 0.4 10.6 1.4 0.93 9.4 1.1 1.7 1 1 1 2 2 2 0 Hom_end-associated Hint FliG_N PF14842.6 EGD91616.2 - 0.63 10.6 2.6 2.3 8.8 0.1 2.8 3 1 1 4 4 3 0 FliG N-terminal domain Baculo_PEP_C PF04513.12 EGD91616.2 - 4.4 7.4 5.2 1.6 8.7 0.5 2.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRM_1 PF00076.22 EGD91617.1 - 9.1e-18 63.9 0.0 1.8e-13 50.1 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGD91617.1 - 0.016 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif GET2 PF08690.10 EGD91617.1 - 0.032 13.9 0.1 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 TERB2 PF15101.6 EGD91617.1 - 0.034 14.2 1.7 0.054 13.5 1.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4834 PF16118.5 EGD91617.1 - 0.5 11.4 3.7 1.2 10.1 3.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Suf PF05843.14 EGD91617.1 - 0.76 9.7 5.4 1.5 8.8 5.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Dickkopf_N PF04706.12 EGD91619.2 - 0.039 14.4 10.4 0.039 14.4 10.4 3.2 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region Ribosomal_S16 PF00886.19 EGD91620.2 - 2.2e-24 85.3 0.1 3.8e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 EGD91621.1 - 3.2e-37 128.1 0.0 3.7e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SL4P PF17618.2 EGD91621.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein PUL PF08324.11 EGD91622.2 - 3.1e-70 236.6 0.2 4.1e-70 236.2 0.2 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EGD91622.2 - 3.4e-44 149.7 0.1 7.4e-44 148.6 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EGD91622.2 - 9.2e-26 89.6 15.6 3.6e-07 30.8 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat WD40 PF00400.32 EGD91623.1 - 2.5e-19 69.2 10.7 3.1e-06 27.8 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD91623.1 - 9.9e-08 32.2 0.2 0.15 12.4 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD91623.1 - 0.0014 17.4 0.6 1.1 7.9 0.2 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGD91623.1 - 0.0036 16.3 0.1 0.79 8.6 0.0 2.5 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 EGD91623.1 - 0.05 12.5 0.0 0.84 8.4 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) RRM_1 PF00076.22 EGD91624.2 - 1.7e-16 59.8 0.0 2.9e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EGD91624.2 - 1.1e-06 29.0 12.6 1.1e-06 29.0 12.6 3.2 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Bot1p PF12298.8 EGD91625.1 - 6.2e-57 192.5 0.5 6.2e-57 192.5 0.5 1.9 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Pkinase PF00069.25 EGD91626.2 - 8.5e-52 176.1 0.0 1.1e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD91626.2 - 2.3e-25 89.4 0.1 1.9e-24 86.4 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD91626.2 - 0.0024 17.3 0.0 0.0053 16.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGD91626.2 - 0.14 11.8 0.3 0.61 9.7 0.2 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGD91626.2 - 0.14 10.9 0.9 0.23 10.2 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EGD91626.2 - 0.2 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.13 EGD91626.2 - 6 6.7 15.5 8.4 6.3 15.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TSP_NTD PF17804.1 EGD91628.1 - 0.15 12.3 10.4 0.18 12.0 10.4 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain SR-25 PF10500.9 EGD91628.1 - 0.32 10.6 25.5 0.44 10.1 25.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Activator_LAG-3 PF11498.8 EGD91628.1 - 0.71 8.8 26.2 0.89 8.5 26.2 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RR_TM4-6 PF06459.12 EGD91628.1 - 1.1 9.1 21.4 1.3 8.7 21.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3381 PF11861.8 EGD91628.1 - 1.1 9.0 23.7 1.9 8.3 23.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) GAGA_bind PF06217.12 EGD91628.1 - 1.7 8.8 16.4 2.3 8.4 16.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family VIR_N PF15912.5 EGD91628.1 - 4.4 6.8 14.1 5.5 6.5 14.1 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal MCM_bind PF09739.9 EGD91628.1 - 6.7 5.0 16.3 7.6 4.8 16.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Serinc PF03348.15 EGD91628.1 - 7.5 5.4 5.5 9.2 5.1 5.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 EGD91628.1 - 7.9 5.1 17.9 9.5 4.9 17.9 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 EGD91628.1 - 9.7 5.0 19.1 11 4.8 19.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AMP-binding PF00501.28 EGD91631.2 - 6.9e-68 229.2 0.2 9.2e-68 228.8 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGD91631.2 - 1.7e-19 70.6 0.2 4.5e-19 69.2 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF111 PF01969.17 EGD91632.2 - 0.16 11.0 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF111 UBA_4 PF14555.6 EGD91633.1 - 2.5e-13 49.6 0.2 4.6e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain Dynactin_p22 PF07426.11 EGD91634.1 - 3e-07 30.5 0.0 4.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 SH3_1 PF00018.28 EGD91635.1 - 3e-09 36.3 0.1 5.2e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGD91635.1 - 4.6e-07 29.6 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGD91635.1 - 6.7e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 EGD91635.1 - 0.09 12.9 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 SH3 domain YhhN PF07947.14 EGD91635.1 - 0.13 11.8 8.3 0.19 11.3 8.3 1.1 1 0 0 1 1 1 0 YhhN family Response_reg PF00072.24 EGD91636.1 - 4.2e-21 75.2 0.0 2.7e-14 53.3 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain DUF2052 PF09747.9 EGD91637.1 - 2.2e-20 73.7 16.5 4.2e-10 40.1 0.4 2.1 1 1 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Spermine_synth PF01564.17 EGD91638.1 - 0.0001 21.8 0.1 0.00021 20.8 0.1 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 EGD91638.1 - 0.032 14.1 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RskA PF10099.9 EGD91638.1 - 0.99 9.7 5.9 1.8 8.8 5.9 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Y_phosphatase3 PF13350.6 EGD91639.1 - 1e-58 199.1 0.0 1.1e-58 198.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Lysis_col PF02402.16 EGD91639.1 - 0.0044 16.7 0.1 0.0097 15.6 0.1 1.5 1 0 0 1 1 1 1 Lysis protein Y_phosphatase2 PF03162.13 EGD91639.1 - 0.0055 16.3 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGD91639.1 - 0.032 13.8 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGD91639.1 - 0.22 11.6 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Peptidase_C12 PF01088.21 EGD91640.1 - 5.9e-50 169.9 0.0 7e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DLIC PF05783.11 EGD91643.1 - 7e-31 107.6 1.9 5.1e-27 94.8 0.0 3.9 2 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 EGD91644.1 - 1.2e-19 69.8 0.1 4.6e-19 68.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGD91644.1 - 1.3e-05 25.2 0.0 4.6e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EGD91644.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 EGD91645.2 - 0.0012 19.1 0.0 0.3 11.4 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGD91645.2 - 0.0021 18.8 0.0 0.63 11.0 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGD91645.2 - 0.028 13.4 0.1 0.092 11.7 0.1 1.7 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EGD91645.2 - 0.11 11.8 0.0 1.1 8.5 0.0 1.9 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Septin PF00735.18 EGD91646.1 - 3.9e-108 361.0 0.3 6.3e-108 360.3 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EGD91646.1 - 9.7e-06 25.7 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGD91646.1 - 0.0011 19.0 4.0 1 9.4 0.0 3.2 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EGD91646.1 - 0.0029 17.2 0.2 0.17 11.4 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGD91646.1 - 0.0079 16.1 0.5 0.0079 16.1 0.5 2.5 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 EGD91646.1 - 0.016 14.5 0.0 0.04 13.2 0.0 1.7 1 0 0 1 1 1 0 AIG1 family IIGP PF05049.13 EGD91646.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 EGD91646.1 - 0.18 12.3 1.3 0.96 10.0 0.0 2.5 2 1 0 2 2 2 0 ABC transporter EB1 PF03271.17 EGD91646.1 - 0.33 11.2 4.3 3.5 8.0 1.3 2.8 2 0 0 2 2 2 0 EB1-like C-terminal motif CNH PF00780.22 EGD91648.1 - 3.1e-81 273.0 0.0 2e-80 270.4 0.0 2.0 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EGD91648.1 - 1.1e-39 135.6 0.0 2.4e-39 134.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EGD91648.1 - 8.9e-38 130.3 0.0 1.6e-37 129.5 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EGD91648.1 - 3.9e-13 49.3 0.0 8.3e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.21 EGD91649.2 - 9.8e-18 64.3 19.8 8.3e-12 45.3 8.7 2.2 2 0 0 2 2 2 2 ATP synthase subunit C NapE PF06796.11 EGD91649.2 - 0.45 10.1 2.4 3.2 7.3 2.1 2.3 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Pkinase PF00069.25 EGD91650.1 - 2.9e-64 217.0 0.0 4e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD91650.1 - 1.8e-34 119.2 0.0 2.4e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD91650.1 - 0.00019 20.8 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PyrBI_leader PF08052.11 EGD91650.1 - 0.0091 15.9 0.1 2.8 8.0 0.0 2.4 2 0 0 2 2 2 2 PyrBI operon leader peptide Haspin_kinase PF12330.8 EGD91650.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGD91650.1 - 0.032 14.1 0.0 0.13 12.2 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2773 PF10971.8 EGD91650.1 - 0.041 14.0 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) Kdo PF06293.14 EGD91650.1 - 0.091 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGD91650.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 EGD91650.1 - 0.23 10.5 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gly_transf_sug PF04488.15 EGD91651.1 - 2.1e-14 53.9 0.0 4.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Trypan_PARP PF05887.11 EGD91651.1 - 0.0023 17.9 9.2 0.0036 17.3 9.2 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Abhydrolase_1 PF00561.20 EGD91653.1 - 8.7e-50 169.8 0.1 2.8e-48 164.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGD91653.1 - 0.00071 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Metallophos PF00149.28 EGD91655.2 - 1.5e-14 55.0 0.0 2.3e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGD91655.2 - 2.7e-08 34.2 0.0 7.1e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EGD91655.2 - 0.012 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily MARVEL PF01284.23 EGD91656.1 - 7.4e-17 61.7 7.7 9.5e-17 61.4 7.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.6 EGD91656.1 - 0.0018 17.9 1.6 0.0028 17.2 1.5 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein PepSY_TM PF03929.16 EGD91656.1 - 3.2 7.4 9.4 0.15 11.7 0.7 2.0 1 1 0 2 2 2 0 PepSY-associated TM region DUF4336 PF14234.6 EGD91657.2 - 4.5e-16 59.0 0.3 3.8e-12 46.0 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) RTBV_P46 PF06216.11 EGD91657.2 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Nse4_C PF08743.10 EGD91658.1 - 1.3e-31 108.7 0.0 3.5e-31 107.3 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EGD91658.1 - 8.2e-16 57.9 0.0 2.3e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE PI3Ka PF00613.20 EGD91659.1 - 4.3e-59 199.0 0.2 6.8e-59 198.4 0.2 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGD91659.1 - 6.9e-46 157.1 0.0 1.4e-30 107.0 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EGD91659.1 - 1.2e-32 112.7 0.0 2e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 HCO3_cotransp PF00955.21 EGD91660.2 - 3.4e-40 138.3 7.0 1.8e-37 129.4 0.6 2.0 1 1 1 2 2 2 2 HCO3- transporter family MMR_HSR1 PF01926.23 EGD91661.1 - 2e-12 47.2 0.0 4.2e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGD91661.1 - 1.1e-06 28.7 0.0 2.3e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EGD91661.1 - 0.00045 19.8 0.2 0.0012 18.4 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 EGD91661.1 - 0.011 16.3 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EGD91661.1 - 0.041 13.4 0.0 0.099 12.2 0.0 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 EGD91661.1 - 0.043 13.0 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MeaB PF03308.16 EGD91661.1 - 0.064 12.2 0.1 0.1 11.5 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Septin PF00735.18 EGD91661.1 - 0.085 12.1 0.0 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 Septin Arf PF00025.21 EGD91661.1 - 0.091 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family TniB PF05621.11 EGD91661.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein NTPase_1 PF03266.15 EGD91661.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 NTPase Roc PF08477.13 EGD91661.1 - 0.16 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EGD91661.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Isy1 PF06246.12 EGD91662.2 - 9.1e-37 127.0 0.6 1.1e-36 126.8 0.6 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Myosin_head PF00063.21 EGD91663.1 - 5.3e-264 877.6 1.4 6.8e-264 877.2 0.0 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 EGD91663.1 - 3.8e-15 54.9 270.3 5.4e-10 37.8 119.5 7.1 1 1 2 4 4 4 3 Myosin tail Myosin_N PF02736.19 EGD91663.1 - 5.7e-12 45.3 0.2 1.4e-11 44.1 0.2 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ADIP PF11559.8 EGD91663.1 - 0.0011 19.1 11.9 0.0011 19.1 11.9 17.7 5 4 12 19 19 19 2 Afadin- and alpha -actinin-Binding DUF1292 PF06949.11 EGD91663.1 - 0.034 15.1 0.0 0.16 12.9 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1292) AAA_22 PF13401.6 EGD91663.1 - 0.49 10.7 0.0 0.49 10.7 0.0 5.4 4 2 0 4 4 4 0 AAA domain AAA_24 PF13479.6 EGD91663.1 - 3.3 7.4 7.2 14 5.3 0.0 3.8 3 0 0 3 3 3 0 AAA domain zf-C3H1 PF10650.9 EGD91664.2 - 1.1e-09 37.8 0.8 1.9e-09 37.1 0.8 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain LMP PF04778.12 EGD91664.2 - 0.011 15.7 1.6 0.045 13.7 1.6 2.1 1 0 0 1 1 1 0 LMP repeated region MFS_1 PF07690.16 EGD91665.1 - 4.5e-45 154.1 27.3 4.5e-45 154.1 27.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD91665.1 - 6.5e-11 41.7 19.7 1.2e-10 40.9 19.7 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EGD91665.1 - 1.2e-06 27.3 3.5 2.1e-06 26.5 3.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EGD91665.1 - 1.2e-05 24.8 1.1 1.2e-05 24.8 1.1 2.3 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF4271 PF14093.6 EGD91665.1 - 0.15 12.0 0.1 0.15 12.0 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4271) DUF4231 PF14015.6 EGD91665.1 - 1.9 9.0 5.8 2.8 8.5 0.4 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) DUF4064 PF13273.6 EGD91665.1 - 2.2 8.6 9.9 3 8.1 0.1 4.5 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) GATase_5 PF13507.6 EGD91666.1 - 1.7e-96 322.3 0.0 2.7e-96 321.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EGD91666.1 - 6.8e-39 133.5 0.1 1.5e-24 86.9 0.1 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EGD91666.1 - 3.4e-32 110.8 0.0 6e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EGD91666.1 - 4.1e-21 75.3 0.0 8.7e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain GCP_N_terminal PF17681.1 EGD91667.1 - 2e-30 106.5 0.5 2e-30 106.5 0.5 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGD91667.1 - 2.2e-23 83.2 10.0 3.1e-23 82.7 2.2 2.3 2 0 0 2 2 2 2 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 EGD91667.1 - 8.3e-05 21.1 1.6 0.00017 20.1 0.4 2.1 2 1 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 Rrp44_S1 PF17215.3 EGD91667.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 S1 domain Glyco_transf_15 PF01793.16 EGD91668.1 - 7.9e-116 386.8 8.1 9.6e-116 386.6 8.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase ACBP PF00887.19 EGD91669.2 - 1.7e-07 31.4 0.2 1.7e-07 31.4 0.2 2.5 2 1 0 2 2 2 1 Acyl CoA binding protein Sporozoite_P67 PF05642.11 EGD91669.2 - 0.057 11.5 2.7 0.068 11.3 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SprA-related PF12118.8 EGD91669.2 - 0.1 11.7 7.9 0.13 11.4 7.9 1.1 1 0 0 1 1 1 0 SprA-related family AAA_11 PF13086.6 EGD91669.2 - 0.19 11.5 3.1 0.25 11.1 3.1 1.3 1 0 0 1 1 1 0 AAA domain TraP PF07296.11 EGD91669.2 - 0.21 10.7 0.5 0.36 10.0 0.5 1.3 1 0 0 1 1 1 0 TraP protein CDC45 PF02724.14 EGD91669.2 - 0.65 8.2 8.9 0.89 7.8 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein NAM-associated PF14303.6 EGD91669.2 - 0.93 10.2 10.6 0.1 13.3 4.5 2.0 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain NOA36 PF06524.12 EGD91669.2 - 2.2 7.5 8.3 3.2 7.0 8.3 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EGD91669.2 - 2.5 6.1 9.2 1.8 6.6 7.8 1.5 2 0 0 2 2 2 0 DNA polymerase phi LSM14 PF12701.7 EGD91670.1 - 3e-26 91.3 0.0 5.5e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EGD91670.1 - 4.5e-18 66.0 3.3 4.5e-18 66.0 3.3 3.4 2 1 1 3 3 3 1 FDF domain SM-ATX PF14438.6 EGD91670.1 - 0.00021 21.3 0.1 0.00061 19.9 0.0 1.8 2 0 0 2 2 2 1 Ataxin 2 SM domain GRP PF07172.11 EGD91670.1 - 1 10.1 27.6 8.6 7.1 1.7 2.8 2 0 0 2 2 2 0 Glycine rich protein family WD40 PF00400.32 EGD91671.1 - 9e-15 54.8 19.1 0.0036 18.1 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD91671.1 - 0.0065 16.7 0.3 8 6.8 0.0 3.8 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGD91671.1 - 0.041 12.5 0.4 0.066 11.9 0.1 1.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Reg_prop PF07494.11 EGD91671.1 - 0.045 14.0 0.0 1.2 9.6 0.0 3.1 2 0 0 2 2 2 0 Two component regulator propeller DUF1513 PF07433.11 EGD91671.1 - 0.051 12.7 0.1 0.32 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.11 EGD91671.1 - 0.12 11.1 0.0 0.32 9.7 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like PQQ_3 PF13570.6 EGD91671.1 - 0.13 12.8 1.0 0.64 10.6 0.0 2.7 3 1 1 4 4 4 0 PQQ-like domain Thioredox_DsbH PF03190.15 EGD91672.2 - 2e-39 135.1 0.0 5.3e-39 133.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Glyco_hydro_9 PF00759.19 EGD91672.2 - 0.087 12.2 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 CAP PF00188.26 EGD91673.1 - 4.2e-16 59.9 5.3 5.7e-16 59.5 5.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PPTA PF01239.22 EGD91673.1 - 1 9.2 3.1 1.9 8.3 3.1 1.5 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat CHCH PF06747.13 EGD91674.2 - 8.4e-06 25.8 15.0 0.00021 21.3 9.0 2.5 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 EGD91674.2 - 3e-05 23.9 10.1 0.00016 21.6 6.9 2.3 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, SCRG1 PF15224.6 EGD91674.2 - 0.062 13.4 2.1 0.098 12.8 2.1 1.3 1 0 0 1 1 1 0 Scrapie-responsive protein 1 Pet191_N PF10203.9 EGD91674.2 - 0.24 11.7 10.3 1.1 9.6 1.6 3.1 2 1 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 EGD91674.2 - 2.4 8.5 11.9 8.2 6.7 5.6 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 EGD91674.2 - 3.8 7.6 14.6 9.5 6.3 1.1 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like KH_1 PF00013.29 EGD91675.2 - 0.0018 18.1 0.0 0.24 11.2 0.0 2.5 2 0 0 2 2 2 2 KH domain Prefoldin PF02996.17 EGD91676.1 - 6.8e-24 84.1 0.1 8.7e-24 83.7 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit tRNA-synt_2b PF00587.25 EGD91677.1 - 3.5e-30 105.3 0.0 1.7e-29 103.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGD91677.1 - 5.5e-09 36.1 0.0 1.4e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain zf-ribbon_3 PF13248.6 EGD91677.1 - 0.067 12.6 0.4 0.067 12.6 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain LANC_like PF05147.13 EGD91679.2 - 1.2e-12 47.1 0.0 4.1e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein Goodbye PF17109.5 EGD91681.2 - 1.6e-05 25.4 2.0 2.5e-05 24.7 0.1 2.4 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain DUF5343 PF17278.2 EGD91681.2 - 0.045 13.8 0.1 0.21 11.7 0.1 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5343) Pkinase PF00069.25 EGD91683.2 - 5.4e-66 222.6 0.0 8.5e-66 222.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD91683.2 - 1.9e-34 119.2 0.0 1.5e-33 116.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGD91683.2 - 2.9e-06 26.3 0.1 5.3e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGD91683.2 - 4.3e-06 26.2 0.1 2.5e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGD91683.2 - 2.2e-05 24.5 0.0 0.0034 17.3 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGD91683.2 - 0.01 14.9 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EGD91683.2 - 0.079 12.3 0.8 0.59 9.5 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 EGD91684.2 - 1.5e-17 63.2 0.1 1e-08 34.8 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGD91684.2 - 0.069 13.2 6.0 0.31 11.1 0.0 3.4 2 1 1 3 3 3 0 RNA binding motif Tubulin PF00091.25 EGD91685.2 - 2.9e-67 226.7 0.0 6e-67 225.7 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGD91685.2 - 1.3e-43 148.2 0.1 2.1e-43 147.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGD91685.2 - 2.3e-06 27.9 0.0 6.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EGD91685.2 - 0.00086 18.6 0.0 0.034 13.3 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EGD91685.2 - 0.0043 16.7 0.0 0.0093 15.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Aldedh PF00171.22 EGD91686.1 - 8.5e-108 360.8 0.0 1e-107 360.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AGT PF11440.8 EGD91687.2 - 0.051 12.6 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Methyltransf_31 PF13847.6 EGD91688.1 - 1e-10 41.6 0.0 1.5e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD91688.1 - 6.2e-10 39.7 0.0 1.2e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD91688.1 - 8.5e-09 35.4 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD91688.1 - 6.1e-08 33.3 0.0 1.2e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD91688.1 - 5.7e-05 23.7 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD91688.1 - 0.035 13.4 0.0 0.084 12.2 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CheR PF01739.18 EGD91688.1 - 0.042 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Isochorismatase PF00857.20 EGD91690.1 - 2.3e-34 119.1 0.1 8.7e-34 117.2 0.1 1.8 2 0 0 2 2 2 1 Isochorismatase family Iso_dh PF00180.20 EGD91690.1 - 5.6e-14 52.0 0.0 8.3e-08 31.8 0.0 2.1 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase TK PF00265.18 EGD91690.1 - 0.016 15.1 0.0 0.089 12.7 0.0 2.1 2 0 0 2 2 2 0 Thymidine kinase Methyltransf_25 PF13649.6 EGD91691.1 - 2.7e-10 40.8 0.0 9e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD91691.1 - 2.8e-06 27.9 0.0 7.9e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD91691.1 - 3.2e-05 23.8 0.0 4.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD91691.1 - 6.4e-05 23.6 0.0 9.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD91691.1 - 6.6e-05 22.7 0.0 8.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD91691.1 - 0.0039 16.6 0.0 0.0051 16.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Abhydrolase_6 PF12697.7 EGD91692.1 - 4.8e-08 33.9 0.0 5.9e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Rad60-SLD PF11976.8 EGD91694.1 - 5.5e-20 71.0 0.3 6.4e-20 70.8 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGD91694.1 - 3.9e-11 42.5 0.2 4.4e-11 42.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family MTCP1 PF08991.10 EGD91695.2 - 3.1e-26 91.4 12.4 3.5e-26 91.2 12.4 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 EGD91695.2 - 0.022 14.9 6.5 0.034 14.3 6.5 1.4 1 0 0 1 1 1 0 CHCH domain Nup84_Nup100 PF04121.13 EGD91696.2 - 3.3e-173 577.6 1.0 4.3e-173 577.3 1.0 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 HBM PF16591.5 EGD91696.2 - 0.017 14.5 0.9 0.017 14.5 0.9 1.8 2 0 0 2 2 2 0 Helical bimodular sensor domain PEP-utilizers_C PF02896.18 EGD91696.2 - 0.15 11.1 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Cation_ATPase_C PF00689.21 EGD91697.1 - 8e-46 156.0 4.8 8e-46 156.0 4.8 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGD91697.1 - 1.9e-34 118.7 4.6 1.9e-34 118.7 4.6 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGD91697.1 - 7.9e-24 83.6 0.1 1.5e-23 82.7 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGD91697.1 - 7.2e-16 59.1 1.7 7.7e-15 55.7 1.7 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGD91697.1 - 1.4e-06 27.9 0.0 1.1e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGD91697.1 - 3.5e-05 23.7 0.6 9.2e-05 22.3 0.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RskA PF10099.9 EGD91697.1 - 0.0093 16.3 1.0 3.1 8.1 0.0 3.3 2 1 0 2 2 2 1 Anti-sigma-K factor rskA LptF_LptG PF03739.14 EGD91697.1 - 0.016 14.1 5.7 0.041 12.7 5.7 1.7 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF1774 PF08611.10 EGD91697.1 - 0.17 12.2 5.3 0.13 12.6 0.4 2.8 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) Nucleo_P87 PF07267.11 EGD91698.1 - 0.28 10.0 8.0 0.32 9.8 8.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 4HBT PF03061.22 EGD91700.1 - 8.9e-11 42.0 0.0 1.5e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily V-ATPase_C PF03223.15 EGD91701.1 - 8.6e-124 413.7 0.0 1e-123 413.5 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.15 EGD91701.1 - 0.031 14.9 0.1 0.071 13.8 0.1 1.6 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Cep57_MT_bd PF06657.13 EGD91701.1 - 0.17 12.3 0.4 28 5.3 0.1 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 APS_kinase PF01583.20 EGD91702.1 - 3e-52 176.7 0.0 5.1e-52 175.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 EGD91702.1 - 2e-07 31.6 0.1 2.3e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGD91702.1 - 0.00012 22.2 2.4 0.00027 21.1 0.0 2.6 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGD91702.1 - 0.0017 18.0 0.6 0.0046 16.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGD91702.1 - 0.0094 15.2 0.8 0.025 13.9 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 EGD91702.1 - 0.042 14.4 0.0 0.042 14.4 0.0 2.4 3 1 0 3 3 3 0 ABC transporter CbiA PF01656.23 EGD91702.1 - 0.072 13.2 0.0 0.19 11.8 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EGD91702.1 - 0.12 12.8 6.1 0.8 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 EGD91702.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.10 EGD91702.1 - 0.14 11.6 0.2 0.41 10.0 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_23 PF13476.6 EGD91702.1 - 1.9 8.9 6.0 11 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain GCV_T PF01571.21 EGD91703.1 - 8.4e-78 261.3 0.0 1.2e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EGD91703.1 - 4.6e-17 61.7 0.3 1.2e-16 60.4 0.3 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Aa_trans PF01490.18 EGD91704.1 - 1.8e-26 92.8 35.3 3.5e-26 91.9 35.3 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Vps5 PF09325.10 EGD91707.2 - 0.0027 17.3 0.7 0.008 15.7 0.4 1.7 2 0 0 2 2 2 1 Vps5 C terminal like Baculo_PEP_C PF04513.12 EGD91707.2 - 0.018 15.1 5.9 0.066 13.3 6.3 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fe-ADH_2 PF13685.6 EGD91707.2 - 0.027 14.2 0.1 0.034 13.8 0.1 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase FapA PF03961.13 EGD91707.2 - 0.046 12.3 0.4 0.067 11.8 0.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A LPP PF04728.13 EGD91707.2 - 0.063 13.7 0.5 0.063 13.7 0.5 2.6 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Topoisom_bac PF01131.20 EGD91709.2 - 3.2e-96 322.9 0.0 5.6e-91 305.6 0.0 2.0 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 EGD91709.2 - 5.4e-11 42.6 0.0 1.3e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Guanylate_kin PF00625.21 EGD91710.2 - 3.3e-47 160.5 0.0 4.4e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 EGD91710.2 - 0.00059 20.4 0.1 0.0017 18.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGD91710.2 - 0.00076 19.8 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGD91710.2 - 0.0025 17.9 0.0 0.034 14.2 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGD91710.2 - 0.0098 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 EGD91710.2 - 0.022 14.9 0.5 0.27 11.4 0.5 2.2 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGD91710.2 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 EGD91710.2 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EGD91710.2 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.6 EGD91710.2 - 0.21 12.0 0.3 0.54 10.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain DUF3738 PF12543.8 EGD91711.2 - 0.05 13.7 1.0 0.074 13.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) Mago_nashi PF02792.14 EGD91712.2 - 1.7e-73 245.4 0.2 1.9e-73 245.3 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein LrgB PF04172.16 EGD91714.2 - 0.0023 17.5 2.9 0.0023 17.5 2.9 2.3 2 1 0 2 2 2 1 LrgB-like family DUF2569 PF10754.9 EGD91714.2 - 2.2 8.7 19.0 1.8 9.0 8.1 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF2569) Pkinase PF00069.25 EGD91716.2 - 1.7e-57 194.8 0.0 2.9e-57 194.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD91716.2 - 3.6e-33 114.9 0.0 5.3e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EGD91716.2 - 2.7e-17 62.3 0.4 5.8e-17 61.2 0.4 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 EGD91716.2 - 5.7e-06 25.8 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGD91716.2 - 3.4e-05 23.3 0.0 6.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGD91716.2 - 0.00021 20.4 0.1 0.00035 19.6 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGD91716.2 - 0.0059 16.5 0.0 0.038 13.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGD91716.2 - 0.064 12.8 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 EGD91716.2 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1604 PF07713.13 EGD91717.1 - 2.3e-42 142.7 8.2 1.5e-41 140.1 2.8 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EGD91717.1 - 9.5e-08 31.8 0.9 2.6e-07 30.4 0.4 2.0 2 0 0 2 2 2 1 G-patch domain Patatin PF01734.22 EGD91717.1 - 0.026 14.7 0.3 0.068 13.3 0.3 1.7 1 0 0 1 1 1 0 Patatin-like phospholipase G-patch_2 PF12656.7 EGD91717.1 - 0.029 14.4 0.0 0.029 14.4 0.0 3.2 4 0 0 4 4 4 0 G-patch domain SLT_2 PF13406.6 EGD91717.1 - 0.15 11.2 0.0 0.15 11.2 0.0 1.9 3 0 0 3 3 3 0 Transglycosylase SLT domain UBD PF16455.5 EGD91718.1 - 8.8e-41 138.4 0.0 1.3e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 EGD91718.1 - 1.8e-05 24.4 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family baeRF_family2 PF18844.1 EGD91718.1 - 0.00022 21.3 2.8 0.00048 20.2 2.8 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 2 Rad60-SLD PF11976.8 EGD91718.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGD91718.1 - 0.016 15.8 0.2 0.035 14.7 0.0 1.6 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain baeRF_family10 PF18854.1 EGD91718.1 - 0.061 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 Nop52 PF05997.12 EGD91719.2 - 7.7e-34 117.4 0.1 1.4e-32 113.2 0.1 2.1 1 1 0 1 1 1 1 Nucleolar protein,Nop52 DUF4519 PF15012.6 EGD91719.2 - 8.5 6.6 5.5 19 5.5 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) SET PF00856.28 EGD91720.1 - 3.4e-19 69.9 0.1 9.2e-19 68.4 0.1 1.8 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 EGD91720.1 - 5.9e-11 43.0 5.3 5.9e-11 43.0 5.3 2.2 3 0 0 3 3 3 1 Pre-SET motif Ion_trans PF00520.31 EGD91722.1 - 8.8e-125 414.8 90.2 2.2e-39 135.2 8.8 4.6 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.32 EGD91722.1 - 0.002 17.5 0.0 0.0062 16.0 0.0 1.9 1 0 0 1 1 1 1 EF hand GPHH PF16905.5 EGD91722.1 - 0.0043 16.8 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_7 PF13499.6 EGD91722.1 - 0.034 14.6 0.3 0.32 11.5 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 EGD91722.1 - 0.051 13.5 0.0 0.31 11.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain FUN14 PF04930.15 EGD91722.1 - 0.061 13.7 0.2 27 5.3 0.0 2.9 2 0 0 2 2 2 0 FUN14 family Proteasom_Rpn13 PF04683.13 EGD91723.1 - 7.5e-26 90.5 0.0 1.2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EGD91723.1 - 6.1e-13 48.9 1.1 3.1e-12 46.6 1.6 1.8 2 0 0 2 2 2 1 UCH-binding domain Ribosomal_L6e PF01159.19 EGD91724.1 - 4.7e-37 126.9 0.0 7.7e-37 126.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e FA_hydroxylase PF04116.13 EGD91725.1 - 2.1e-17 63.7 13.0 2.1e-17 63.7 13.0 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.25 EGD91726.1 - 3e-24 85.6 0.0 4.2e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD91726.1 - 7.2e-12 45.4 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGD91726.1 - 3.3e-10 40.2 0.1 2.7e-09 37.2 0.1 2.0 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGD91726.1 - 0.016 14.6 0.0 0.033 13.6 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 EGD91726.1 - 0.016 14.5 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 EGD91726.1 - 0.018 15.4 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 EGD91726.1 - 0.026 14.6 0.0 0.081 13.0 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EGD91726.1 - 0.038 13.4 0.0 0.069 12.6 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGD91726.1 - 0.073 13.3 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sas10 PF09368.10 EGD91727.1 - 1.9e-28 98.7 7.6 1.9e-28 98.7 7.6 3.4 5 0 0 5 5 5 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EGD91727.1 - 1.3e-10 41.8 0.0 6e-10 39.6 0.0 2.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family MutS_V PF00488.21 EGD91728.1 - 1.7e-49 168.4 0.1 3.3e-49 167.5 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGD91728.1 - 2e-17 64.1 0.7 9.4e-17 61.9 0.0 2.2 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EGD91728.1 - 0.0012 19.2 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA PF00004.29 EGD91728.1 - 0.028 14.8 0.0 0.08 13.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EGD91729.1 - 3.1e-46 157.6 0.0 1.9e-44 151.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGD91729.1 - 2.8e-35 120.3 1.8 2.8e-35 120.3 1.8 2.5 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EGD91729.1 - 5.7e-27 93.6 0.1 2.2e-26 91.7 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EGD91729.1 - 2.1e-17 63.8 0.1 8.1e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGD91729.1 - 1.5e-12 47.7 0.1 1.7e-07 31.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGD91729.1 - 2.7e-08 34.4 9.9 0.00021 21.7 0.1 4.4 3 2 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.26 EGD91729.1 - 2.9e-08 33.6 0.3 0.00021 21.1 0.1 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 EGD91729.1 - 1.4e-06 28.6 2.8 0.019 15.2 0.0 3.8 3 2 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EGD91729.1 - 1.1e-05 25.3 0.0 0.084 12.6 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein TniB PF05621.11 EGD91729.1 - 3.4e-05 23.3 0.1 0.029 13.8 0.0 3.6 3 1 0 3 3 2 1 Bacterial TniB protein AAA_14 PF13173.6 EGD91729.1 - 3.6e-05 23.8 0.2 0.12 12.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 EGD91729.1 - 3.7e-05 23.3 0.0 0.067 12.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 EGD91729.1 - 4.1e-05 23.6 0.3 0.14 12.0 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_28 PF13521.6 EGD91729.1 - 0.0002 21.6 1.5 0.042 14.1 0.0 3.4 3 1 1 4 4 3 1 AAA domain AAA_18 PF13238.6 EGD91729.1 - 0.00036 21.1 0.1 1.5 9.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EGD91729.1 - 0.00073 19.5 6.1 2.7 7.8 0.0 4.2 3 2 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGD91729.1 - 0.00094 19.0 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EGD91729.1 - 0.001 18.7 0.1 0.16 11.5 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 EGD91729.1 - 0.0041 16.5 0.2 2.2 7.6 0.0 3.0 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGD91729.1 - 0.0045 17.4 0.1 2 8.8 0.0 2.9 2 1 0 2 2 2 1 RNA helicase ResIII PF04851.15 EGD91729.1 - 0.0045 17.0 0.0 7.3 6.6 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGD91729.1 - 0.0054 17.1 0.9 0.17 12.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGD91729.1 - 0.0075 16.8 0.8 0.67 10.5 0.0 3.0 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 EGD91729.1 - 0.011 15.7 0.9 1.5 8.7 0.0 2.8 3 0 0 3 3 2 0 RsgA GTPase AAA_33 PF13671.6 EGD91729.1 - 0.011 15.9 0.1 4.7 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGD91729.1 - 0.012 15.3 0.0 0.49 10.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TrwB_AAD_bind PF10412.9 EGD91729.1 - 0.013 14.5 0.1 0.4 9.6 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 EGD91729.1 - 0.015 15.3 1.2 6.4 6.8 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EGD91729.1 - 0.017 14.3 0.3 0.66 9.1 0.2 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 EGD91729.1 - 0.02 15.1 0.1 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 EGD91729.1 - 0.02 14.1 0.0 1.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 EGD91729.1 - 0.023 14.3 0.2 0.47 10.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 EGD91729.1 - 0.038 13.5 2.5 0.41 10.1 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain FapA PF03961.13 EGD91729.1 - 0.045 12.4 3.3 0.083 11.5 3.3 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_21 PF13304.6 EGD91729.1 - 0.07 12.9 0.2 1 9.1 0.0 2.9 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP_bind_1 PF03029.17 EGD91729.1 - 0.13 12.0 0.1 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EGD91729.1 - 0.19 11.4 8.0 0.17 11.6 0.4 3.8 4 1 0 4 4 4 0 AAA domain HisKA_2 PF07568.12 EGD91729.1 - 0.24 11.5 1.4 0.78 9.9 0.8 2.2 2 0 0 2 2 1 0 Histidine kinase DUF4094 PF13334.6 EGD91729.1 - 0.36 11.3 2.3 0.72 10.3 0.6 2.4 3 0 0 3 3 1 0 Domain of unknown function (DUF4094) V_ATPase_I PF01496.19 EGD91729.1 - 0.77 7.6 3.0 1.1 7.1 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EF1_GNE PF00736.19 EGD91730.1 - 1e-31 108.9 0.8 1e-31 108.9 0.8 1.5 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EGD91730.1 - 5.8e-07 29.8 1.7 5.8e-07 29.8 1.7 1.9 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region DUF4604 PF15377.6 EGD91730.1 - 0.04 14.3 1.0 0.055 13.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) GST_C PF00043.25 EGD91730.1 - 0.079 13.2 0.1 0.27 11.5 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MMgT PF10270.9 EGD91731.1 - 4.3e-33 113.6 0.0 5.2e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Cas_Csy4 PF09618.10 EGD91733.1 - 0.012 15.8 0.4 0.012 15.7 0.4 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) UQ_con PF00179.26 EGD91734.2 - 1.5e-36 125.2 0.0 2.6e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGD91734.2 - 0.0037 17.0 0.5 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic E2 family B RNB PF00773.19 EGD91735.2 - 3.6e-79 266.4 0.0 9.9e-79 265.0 0.0 1.8 2 0 0 2 2 2 1 RNB domain Dis3l2_C_term PF17877.1 EGD91735.2 - 2.3e-25 88.7 0.0 6.9e-25 87.2 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 EGD91735.2 - 1.5e-24 85.8 0.0 3.3e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EGD91735.2 - 0.00071 19.7 0.0 0.24 11.6 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 EGD91735.2 - 0.0016 18.2 0.0 0.0047 16.7 0.0 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain TFIIA PF03153.13 EGD91735.2 - 0.0053 16.8 14.1 0.0053 16.8 14.1 3.4 2 1 1 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF4667 PF15700.5 EGD91735.2 - 0.009 16.1 3.0 0.009 16.1 3.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4667) GLE1 PF07817.13 EGD91738.1 - 1.2e-46 158.9 0.0 2.3e-46 158.1 0.0 1.4 1 0 0 1 1 1 1 GLE1-like protein Asp-B-Hydro_N PF05279.11 EGD91738.1 - 0.11 12.5 37.1 0.17 12.0 37.1 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AF-4 PF05110.13 EGD91738.1 - 0.72 7.9 32.3 0.93 7.5 32.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3425 PF11905.8 EGD91739.2 - 1.5e-10 41.1 0.0 2.7e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) PRKG1_interact PF15898.5 EGD91739.2 - 0.029 15.2 4.4 0.048 14.6 4.4 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF2508 PF10704.9 EGD91740.1 - 0.02 15.0 0.4 0.02 15.0 0.4 5.6 7 1 0 7 7 7 0 Protein of unknown function (DUF2508) PAM2 PF07145.15 EGD91740.1 - 3.1 7.7 11.7 12 5.8 0.1 4.1 4 0 0 4 4 4 0 Ataxin-2 C-terminal region Glyco_hydro_17 PF00332.18 EGD91741.1 - 4.7e-33 115.1 0.0 5.7e-32 111.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Myb_DNA-binding PF00249.31 EGD91742.2 - 0.015 15.5 4.1 7.5 6.8 0.0 3.4 3 1 0 3 3 3 0 Myb-like DNA-binding domain Carbam_trans_C PF16861.5 EGD91742.2 - 0.021 14.4 0.1 0.029 14.0 0.1 1.2 1 0 0 1 1 1 0 Carbamoyltransferase C-terminus MADF_DNA_bdg PF10545.9 EGD91742.2 - 0.029 14.7 4.1 0.035 14.4 2.7 1.9 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 EGD91742.2 - 0.029 14.6 5.8 0.23 11.8 4.6 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain FGF-BP1 PF06473.12 EGD91742.2 - 0.073 12.9 2.5 0.094 12.5 2.5 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) GIDA_assoc PF13932.6 EGD91742.2 - 0.19 11.9 1.8 0.24 11.5 1.8 1.1 1 0 0 1 1 1 0 GidA associated domain PRIMA1 PF16101.5 EGD91742.2 - 1.6 8.8 6.5 2.8 8.0 6.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EMP24_GP25L PF01105.24 EGD91743.1 - 7.4e-47 159.6 0.1 8.7e-47 159.4 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Vac_ImportDeg PF09783.9 EGD91743.1 - 0.038 13.8 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Vacuolar import and degradation protein Y_Y_Y PF07495.13 EGD91743.1 - 0.049 13.6 0.1 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 Y_Y_Y domain DUF4793 PF16041.5 EGD91743.1 - 0.057 13.6 0.1 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4793) DUF5643 PF18705.1 EGD91743.1 - 0.078 12.9 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5643) DUF1408 PF07193.11 EGD91743.1 - 0.13 12.4 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) GRP PF07172.11 EGD91744.1 - 0.00057 20.5 8.8 0.00083 20.0 8.8 1.2 1 0 0 1 1 1 1 Glycine rich protein family MAP17 PF15807.5 EGD91744.1 - 0.00064 20.0 0.0 0.0013 19.0 0.0 1.5 2 0 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PSI PF01437.25 EGD91744.1 - 0.0013 19.2 7.6 0.0024 18.4 7.6 1.5 1 0 0 1 1 1 1 Plexin repeat SARAF PF06682.12 EGD91744.1 - 0.0023 17.7 0.0 0.0027 17.4 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis TNFR_16_TM PF18422.1 EGD91744.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain TM231 PF10149.9 EGD91744.1 - 0.2 10.9 0.1 0.29 10.4 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 231 PSI_integrin PF17205.3 EGD91744.1 - 0.3 10.9 9.4 0.59 9.9 9.4 1.4 1 0 0 1 1 1 0 Integrin plexin domain FeoB_associated PF12669.7 EGD91744.1 - 0.37 11.2 5.3 0.46 10.9 0.0 2.5 2 1 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF3237 PF11578.8 EGD91745.1 - 5.3e-44 149.7 0.1 5.9e-44 149.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Lant_dehydr_C PF14028.6 EGD91746.2 - 0.097 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term SRP72 PF08492.12 EGD91746.2 - 0.51 10.8 8.9 1 9.8 5.5 2.6 2 0 0 2 2 2 0 SRP72 RNA-binding domain TilS_C PF11734.8 EGD91746.2 - 1.5 8.3 4.1 18 4.8 1.2 3.2 2 1 1 3 3 3 0 TilS substrate C-terminal domain PBP1_TM PF14812.6 EGD91746.2 - 4.5 7.7 8.7 1.4 9.4 4.9 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal APH PF01636.23 EGD91747.1 - 4.6e-15 56.2 0.2 7.6e-15 55.5 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EGD91747.1 - 0.0089 15.3 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase tRNA-synt_1b PF00579.25 EGD91748.1 - 3.8e-24 85.5 0.0 7.3e-24 84.6 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) 14-3-3 PF00244.20 EGD91750.1 - 3.3e-08 33.3 0.1 5.2e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 14-3-3 protein Acyl-CoA_dh_1 PF00441.24 EGD91751.1 - 1.1e-32 113.4 0.6 1.5e-32 112.9 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGD91751.1 - 2.3e-22 79.0 0.0 3.9e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGD91751.1 - 5.5e-13 49.6 0.1 2.2e-12 47.7 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGD91751.1 - 8.3e-05 22.9 0.1 0.00012 22.4 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.18 EGD91752.2 - 1.4e-08 34.1 0.5 2.4e-08 33.3 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HpcH_HpaI PF03328.14 EGD91753.2 - 3.1e-30 105.0 0.0 4.1e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.6 EGD91753.2 - 0.029 13.8 0.3 0.82 9.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase CHORD PF04968.12 EGD91754.1 - 4.4e-50 168.3 20.2 2.4e-25 89.0 7.0 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 EGD91754.1 - 7.7e-13 49.3 0.2 1.1e-12 48.7 0.2 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.19 EGD91754.1 - 0.27 11.1 8.9 3.2 7.6 0.3 3.2 3 0 0 3 3 3 0 BTK motif Choline_kinase PF01633.20 EGD91755.1 - 1.4e-44 152.2 0.0 2.1e-43 148.4 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EGD91755.1 - 6.8e-09 36.0 1.0 6e-08 32.9 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3050 PF11251.8 EGD91756.2 - 0.078 12.6 0.8 0.44 10.2 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3050) Voldacs PF03517.13 EGD91756.2 - 0.25 11.5 8.4 0.38 10.9 8.4 1.3 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Sod_Cu PF00080.20 EGD91757.1 - 8.1e-09 35.8 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF3405 PF11885.8 EGD91762.1 - 1.3e-231 769.7 1.7 1.5e-231 769.5 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Mucin15 PF15672.5 EGD91763.1 - 0.00032 20.3 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 SARAF PF06682.12 EGD91763.1 - 0.14 11.8 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Arf PF00025.21 EGD91767.1 - 2.6e-79 264.7 0.1 2.9e-79 264.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGD91767.1 - 7.6e-15 54.8 0.0 9.2e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGD91767.1 - 2e-14 53.9 0.1 2.7e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGD91767.1 - 3.2e-13 49.6 1.7 2.1e-09 37.0 0.4 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGD91767.1 - 3.8e-13 49.4 0.0 4.2e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGD91767.1 - 2e-10 40.4 0.0 2.4e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGD91767.1 - 3.3e-06 27.2 0.0 4.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGD91767.1 - 0.0079 15.5 0.5 0.021 14.2 0.5 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 EGD91767.1 - 0.025 14.8 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas2 Acetyltransf_1 PF00583.25 EGD91768.1 - 1.7e-12 47.6 0.0 2.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGD91768.1 - 4.8e-08 33.0 0.0 2.2e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGD91768.1 - 5.8e-08 33.1 0.0 8.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD91768.1 - 7.8e-06 25.8 0.0 4.6e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 EGD91768.1 - 9.9e-05 23.0 0.1 0.00037 21.2 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGD91768.1 - 0.00063 19.5 0.2 0.0017 18.0 0.0 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGD91768.1 - 0.0089 16.1 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EGD91768.1 - 0.048 13.8 0.3 0.32 11.1 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Ribosomal_L1 PF00687.21 EGD91769.2 - 6.6e-47 159.9 0.2 8.3e-47 159.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family WH2 PF02205.20 EGD91771.1 - 2.9e-10 39.6 0.3 2.9e-10 39.6 0.3 2.0 2 0 0 2 2 2 1 WH2 motif LSM PF01423.22 EGD91773.1 - 1.9e-16 59.5 0.1 2.5e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain SURF4 PF02077.15 EGD91776.1 - 2.8e-94 315.7 7.1 3.1e-94 315.5 7.1 1.0 1 0 0 1 1 1 1 SURF4 family DUF1405 PF07187.11 EGD91776.1 - 0.0096 15.9 3.0 0.0096 15.9 3.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1405) DoxX PF07681.12 EGD91776.1 - 0.03 14.9 20.1 0.11 13.2 5.1 3.1 3 2 0 3 3 3 0 DoxX UPF0139 PF03669.13 EGD91776.1 - 0.043 13.7 0.7 0.043 13.7 0.7 2.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0139) TMIE PF16038.5 EGD91776.1 - 4.5 7.2 6.7 12 5.8 0.4 2.7 2 0 0 2 2 2 0 TMIE protein Oxidored_q2 PF00420.24 EGD91778.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L ANAPC1 PF12859.7 EGD91778.1 - 5.8 7.5 6.2 26 5.4 0.8 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 1 Amidase PF01425.21 EGD91779.1 - 4.7e-94 315.9 0.0 9.1e-94 315.0 0.0 1.4 1 1 0 1 1 1 1 Amidase Glycos_transf_1 PF00534.20 EGD91780.1 - 3.4e-13 49.5 0.0 6.2e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGD91780.1 - 1.4e-07 32.0 0.0 3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGD91780.1 - 0.059 13.8 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 HLH PF00010.26 EGD91782.2 - 4.3e-14 52.2 0.7 1e-13 51.0 0.7 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GDH_N PF12466.8 EGD91782.2 - 0.029 14.6 0.3 0.11 12.8 0.3 2.0 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Spt20 PF12090.8 EGD91782.2 - 7.8 6.0 16.8 0.66 9.5 11.3 1.9 2 0 0 2 2 2 0 Spt20 family IU_nuc_hydro PF01156.19 EGD91783.1 - 3.4e-47 161.5 0.0 4.9e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase UvrD_C_2 PF13538.6 EGD91784.1 - 0.019 14.8 1.0 0.045 13.6 1.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Fungal_trans PF04082.18 EGD91785.1 - 2.2e-15 56.4 1.6 3.4e-15 55.8 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD91785.1 - 6.2e-08 32.6 9.2 1.6e-07 31.4 9.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIP_1 PF08995.10 EGD91785.1 - 0.13 12.6 4.2 31 5.0 0.0 2.8 2 1 0 2 2 2 0 Necrosis inducing protein-1 p450 PF00067.22 EGD91786.2 - 4.6e-40 137.7 0.0 6.9e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Mpv17_PMP22 PF04117.12 EGD91786.2 - 0.1 12.8 0.8 3.2 8.1 0.7 2.7 2 0 0 2 2 2 0 Mpv17 / PMP22 family Arylsulfotran_2 PF14269.6 EGD91788.2 - 1.1e-31 110.3 0.1 2e-31 109.5 0.1 1.4 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) p450 PF00067.22 EGD91789.2 - 5.7e-52 177.0 0.0 7.2e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.22 EGD91790.2 - 1.1e-28 100.4 15.2 1.9e-28 99.6 15.2 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGD91790.2 - 1.1e-14 54.8 0.0 2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_M14 PF00246.24 EGD91793.1 - 2.1e-81 273.9 0.1 4.5e-81 272.8 0.0 1.5 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EGD91793.1 - 5.8e-11 42.6 0.0 1.5e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Cellulase PF00150.18 EGD91793.1 - 0.041 13.3 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) AstE_AspA PF04952.14 EGD91793.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Fungal_trans PF04082.18 EGD91794.2 - 1.4e-14 53.8 0.1 2.3e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SOG2 PF10428.9 EGD91794.2 - 0.0097 15.2 7.2 0.012 14.8 7.2 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Rox3 PF08633.10 EGD91795.2 - 2.4e-66 223.9 0.2 2.4e-66 223.9 0.2 1.8 2 1 1 3 3 3 1 Rox3 mediator complex subunit HAD_2 PF13419.6 EGD91796.2 - 2.1e-08 34.5 0.0 5e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGD91796.2 - 3.7e-06 27.4 0.0 5.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Thr_synth_N PF14821.6 EGD91797.1 - 3.1e-28 97.8 0.0 1.2e-27 96.0 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 EGD91797.1 - 1.2e-15 57.7 0.0 1.7e-14 53.9 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4202 PF13875.6 EGD91798.1 - 1e-77 260.2 2.9 1.2e-77 260.1 2.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) VIT1 PF01988.19 EGD91799.1 - 6.6e-60 202.6 2.5 7.7e-60 202.4 2.5 1.0 1 0 0 1 1 1 1 VIT family MAGI_u5 PF16666.5 EGD91801.2 - 0.65 10.2 16.8 0.054 13.6 3.7 2.6 2 0 0 2 2 2 0 Unstructured region on MAGI VPS9 PF02204.18 EGD91802.2 - 1.3e-30 105.6 0.1 2.3e-30 104.9 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EGD91802.2 - 9.2e-17 61.1 0.1 2.1e-16 60.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 EGD91802.2 - 5.2e-09 35.6 0.2 1.5e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 CUE domain Asn_synthase PF00733.21 EGD91803.2 - 1.2e-15 58.1 2.6 1.3e-05 25.0 0.1 3.1 2 1 1 3 3 3 3 Asparagine synthase NAD_synthase PF02540.17 EGD91803.2 - 0.08 12.1 0.1 0.55 9.3 0.1 2.0 1 1 1 2 2 2 0 NAD synthase bZIP_1 PF00170.21 EGD91804.1 - 5.5e-08 32.8 6.7 9.5e-08 32.0 6.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGD91804.1 - 1.9e-07 31.0 6.9 3.7e-07 30.1 6.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGD91804.1 - 0.005 17.3 5.6 0.01 16.4 5.6 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Sugarporin_N PF11471.8 EGD91804.1 - 0.0061 16.5 3.7 0.017 15.1 3.7 1.7 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension ASD2 PF08687.11 EGD91804.1 - 0.019 14.5 0.2 0.025 14.2 0.2 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF4094 PF13334.6 EGD91804.1 - 0.044 14.2 0.7 0.07 13.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Hamartin PF04388.12 EGD91804.1 - 1.3 7.6 8.5 1.5 7.4 8.5 1.1 1 0 0 1 1 1 0 Hamartin protein Sld5 PF05916.11 EGD91809.2 - 2.4e-12 47.3 0.5 9.4e-12 45.4 0.5 2.0 1 1 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 EGD91809.2 - 0.13 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus HMG_box PF00505.19 EGD91811.1 - 1e-09 38.6 0.8 2.4e-09 37.5 0.8 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box PAXIP1_C PF15364.6 EGD91811.1 - 0.024 14.9 1.1 0.052 13.9 1.1 1.6 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein PHD PF00628.29 EGD91814.1 - 2.1e-09 37.1 12.4 1.1e-08 34.9 10.1 2.4 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EGD91814.1 - 0.0015 18.1 5.4 0.0015 18.1 5.4 2.0 2 0 0 2 2 2 1 PHD-finger C1_2 PF03107.16 EGD91814.1 - 6.7 7.1 9.1 0.93 9.9 1.9 2.9 3 0 0 3 3 3 0 C1 domain Rcd1 PF04078.13 EGD91815.1 - 7.8e-126 418.6 3.5 9.6e-126 418.4 3.5 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Macoilin PF09726.9 EGD91815.1 - 0.027 13.0 6.2 0.033 12.8 6.2 1.1 1 0 0 1 1 1 0 Macoilin family OMP_b-brl PF13505.6 EGD91815.1 - 0.12 12.5 0.9 0.18 11.9 0.9 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain EPL1 PF10513.9 EGD91815.1 - 0.37 11.2 6.6 0.59 10.5 6.6 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like TAF4 PF05236.14 EGD91815.1 - 0.7 9.6 9.4 1.1 9.0 9.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PAT1 PF09770.9 EGD91815.1 - 1.2 7.3 20.4 1.4 7.1 20.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 EGD91815.1 - 1.3 8.9 29.1 1.7 8.5 29.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Otopetrin PF03189.13 EGD91815.1 - 1.6 7.4 6.6 0.11 11.3 0.9 1.7 2 0 0 2 2 2 0 Otopetrin Lin-8 PF03353.15 EGD91815.1 - 2.2 7.8 15.1 3.1 7.3 15.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DDRGK PF09756.9 EGD91815.1 - 2.4 7.7 6.6 3.8 7.1 6.6 1.2 1 0 0 1 1 1 0 DDRGK domain NST1 PF13945.6 EGD91815.1 - 3.4 7.7 11.8 5 7.2 11.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF4407 PF14362.6 EGD91815.1 - 4.8 6.4 8.9 8.2 5.7 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med15 PF09606.10 EGD91815.1 - 5.3 5.6 34.6 6.8 5.2 34.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S64 PF08192.11 EGD91815.1 - 6.4 5.1 9.9 10 4.5 9.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.7 EGD91815.1 - 9.1 4.3 10.1 16 3.5 10.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4690 PF15756.5 EGD91816.1 - 0.011 16.3 1.7 0.034 14.8 1.7 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF4834 PF16118.5 EGD91816.1 - 0.064 14.2 0.0 3.5 8.6 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Mito_carr PF00153.27 EGD91820.1 - 2.5e-19 69.0 0.0 3e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein NP1-WLL PF11733.8 EGD91820.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Non-capsid protein NP1 Polysacc_deac_1 PF01522.21 EGD91821.2 - 3.5e-12 46.3 0.4 1e-10 41.6 0.0 2.4 1 1 1 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGD91821.2 - 0.033 13.4 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 SOG2 PF10428.9 EGD91821.2 - 0.39 9.9 12.5 0.48 9.6 12.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF908 PF06012.12 EGD91821.2 - 9.4 5.5 11.6 14 5.0 11.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Prefoldin_2 PF01920.20 EGD91823.1 - 2.5e-20 72.4 6.4 3.1e-20 72.1 6.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit T6PP_N PF18572.1 EGD91823.1 - 0.0022 17.8 2.3 0.0089 15.9 2.3 1.8 1 1 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF4407 PF14362.6 EGD91823.1 - 0.0061 15.9 0.8 0.0083 15.5 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CCDC-167 PF15188.6 EGD91823.1 - 0.008 16.5 1.4 0.014 15.7 1.4 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 Spc24 PF08286.11 EGD91823.1 - 0.0085 16.3 3.5 0.18 12.0 0.3 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF3450 PF11932.8 EGD91823.1 - 0.0099 15.2 5.9 0.67 9.2 1.4 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EGD91823.1 - 0.01 16.1 7.3 0.06 13.5 0.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 EGD91823.1 - 0.011 16.2 1.8 0.011 16.2 1.8 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DUF5082 PF16888.5 EGD91823.1 - 0.016 15.5 3.7 0.14 12.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) FlxA PF14282.6 EGD91823.1 - 0.018 15.0 8.0 1.6 8.8 3.7 2.2 2 0 0 2 2 2 0 FlxA-like protein Tektin PF03148.14 EGD91823.1 - 0.02 13.7 6.5 0.034 12.9 0.5 2.0 2 0 0 2 2 2 0 Tektin family HAUS-augmin3 PF14932.6 EGD91823.1 - 0.022 14.3 4.2 0.72 9.4 0.5 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Jnk-SapK_ap_N PF09744.9 EGD91823.1 - 0.024 14.9 0.7 0.024 14.9 0.7 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Val_tRNA-synt_C PF10458.9 EGD91823.1 - 0.031 14.5 0.4 0.031 14.5 0.4 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm CdvA PF18822.1 EGD91823.1 - 0.034 14.0 5.6 0.16 11.8 1.3 2.6 2 1 0 2 2 2 0 CdvA-like coiled-coil domain Prefoldin PF02996.17 EGD91823.1 - 0.04 13.8 6.5 0.23 11.4 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit BLOC1_2 PF10046.9 EGD91823.1 - 0.046 14.0 4.7 0.1 12.9 0.4 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 EGD91823.1 - 0.049 13.5 3.0 1.9 8.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TMCO5 PF14992.6 EGD91823.1 - 0.05 13.2 3.0 0.063 12.8 3.0 1.1 1 0 0 1 1 1 0 TMCO5 family AIP3 PF03915.13 EGD91823.1 - 0.056 12.5 3.4 0.065 12.3 3.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 SKA2 PF16740.5 EGD91823.1 - 0.059 13.2 4.7 0.24 11.2 0.2 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Snf7 PF03357.21 EGD91823.1 - 0.06 12.9 5.1 1.2 8.7 0.4 2.1 2 0 0 2 2 2 0 Snf7 DUF2681 PF10883.8 EGD91823.1 - 0.062 13.7 4.9 0.65 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4140 PF13600.6 EGD91823.1 - 0.075 13.5 3.0 3.6 8.1 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4618 PF15397.6 EGD91823.1 - 0.088 12.2 6.7 0.42 10.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) CC2-LZ PF16516.5 EGD91823.1 - 0.11 12.9 4.8 4.2 7.8 0.5 2.1 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Phage_Mu_Gam PF07352.12 EGD91823.1 - 0.17 11.8 4.1 0.27 11.1 0.2 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein IFP_35_N PF07334.13 EGD91823.1 - 0.17 11.9 4.5 2.6 8.2 0.5 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SlyX PF04102.12 EGD91823.1 - 0.26 12.0 7.1 6.8 7.4 0.1 2.2 2 0 0 2 2 2 0 SlyX DUF4200 PF13863.6 EGD91823.1 - 0.27 11.6 7.4 4.1 7.8 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) PspA_IM30 PF04012.12 EGD91823.1 - 0.3 10.7 7.9 1.6 8.3 2.0 2.1 2 0 0 2 2 2 0 PspA/IM30 family Cnn_1N PF07989.11 EGD91823.1 - 0.37 11.0 8.6 0.13 12.4 1.1 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Uso1_p115_C PF04871.13 EGD91823.1 - 0.48 10.8 4.6 1.4 9.3 0.5 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Syntaxin-6_N PF09177.11 EGD91823.1 - 0.51 10.9 4.3 2.5 8.7 4.3 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal APG6_N PF17675.1 EGD91823.1 - 0.72 10.4 7.2 9.6 6.7 6.6 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 EGD91823.1 - 0.73 9.9 7.6 0.23 11.5 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 EGD91823.1 - 0.79 9.5 7.9 1.6 8.6 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Fungal_TACC PF12709.7 EGD91823.1 - 0.8 10.2 6.4 0.91 10.0 0.3 2.2 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins bZIP_1 PF00170.21 EGD91823.1 - 1.1 9.5 6.1 0.58 10.3 2.1 2.2 2 0 0 2 2 2 0 bZIP transcription factor THOC7 PF05615.13 EGD91823.1 - 1.1 9.5 11.1 3 8.1 0.9 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 Swi5 PF07061.11 EGD91823.1 - 1.2 9.3 9.1 1.5 8.9 2.3 2.2 2 0 0 2 2 2 0 Swi5 Fzo_mitofusin PF04799.13 EGD91823.1 - 2.2 7.8 6.8 0.3 10.6 0.7 2.0 1 1 0 2 2 2 0 fzo-like conserved region Csm1_N PF18504.1 EGD91823.1 - 5 7.5 10.6 0.58 10.5 1.5 2.4 2 1 0 2 2 2 0 Csm1 N-terminal domain YabA PF06156.13 EGD91823.1 - 6.1 7.6 9.5 4.4 8.0 1.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Aminotran_1_2 PF00155.21 EGD91824.2 - 1.4e-13 50.7 0.0 1.9e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF5615 PF18480.1 EGD91824.2 - 0.068 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) 2_5_RNA_ligase2 PF13563.6 EGD91828.1 - 1.9e-32 112.3 0.1 6e-32 110.7 0.1 1.8 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.17 EGD91828.1 - 1.2e-21 76.8 0.0 2.2e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain MJ1316 PF04457.12 EGD91828.1 - 1.4e-20 73.8 0.6 3.6e-20 72.5 0.6 1.8 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Exo_endo_phos PF03372.23 EGD91828.1 - 1.8e-06 27.6 0.1 4e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 EGD91828.1 - 0.00066 19.9 0.0 0.0026 18.0 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain LigT_PEase PF02834.16 EGD91828.1 - 0.03 14.5 0.1 0.1 12.8 0.1 2.0 1 0 0 1 1 1 0 LigT like Phosphoesterase BTRD1 PF17660.1 EGD91829.1 - 1.4e-57 191.3 14.8 2.9e-15 55.8 0.1 5.0 5 0 0 5 5 5 5 Bacterial tandem repeat domain 1 rve_2 PF13333.6 EGD91829.1 - 0.001 19.2 0.1 0.064 13.4 0.1 3.0 3 0 0 3 3 3 1 Integrase core domain UvrA_inter PF17760.1 EGD91829.1 - 0.075 13.1 0.0 18 5.5 0.0 3.0 3 0 0 3 3 3 0 UvrA interaction domain Methyltransf_25 PF13649.6 EGD91830.1 - 3.8e-09 37.1 0.0 9.3e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD91830.1 - 8e-07 29.7 0.0 1.5e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD91830.1 - 9.5e-06 25.5 0.0 6.9e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD91830.1 - 3.9e-05 23.5 0.0 6.8e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD91830.1 - 0.00029 21.4 0.0 0.0025 18.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD91830.1 - 0.00067 19.1 0.0 0.0021 17.5 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_20 PF12147.8 EGD91830.1 - 0.0021 17.3 0.0 0.014 14.6 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Sulfotransfer_4 PF17784.1 EGD91831.1 - 4.4e-56 190.1 0.0 5.1e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGD91831.1 - 0.0041 17.5 0.5 0.21 11.9 0.5 2.6 1 1 0 1 1 1 1 Sulfotransferase family Cation_efflux PF01545.21 EGD91832.1 - 2.5e-14 53.5 8.5 3.1e-14 53.2 8.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGD91832.1 - 1.2e-10 41.4 0.2 2.9e-10 40.1 0.2 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter FlgN PF05130.12 EGD91832.1 - 0.14 12.7 2.2 0.29 11.6 2.2 1.4 1 0 0 1 1 1 0 FlgN protein Amidase PF01425.21 EGD91833.2 - 3.4e-83 280.1 0.0 4.1e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 Amidase adh_short_C2 PF13561.6 EGD91834.1 - 1e-41 143.0 2.6 1.3e-41 142.7 2.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD91834.1 - 5.8e-39 133.6 0.8 6.9e-39 133.3 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD91834.1 - 1.4e-10 41.4 0.2 2.3e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 KR domain Glyco_transf_20 PF00982.21 EGD91835.2 - 5.3e-69 233.1 0.1 1.1e-67 228.8 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 EGD91835.2 - 0.0073 16.0 0.1 0.009 15.7 0.1 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Abhydrolase_1 PF00561.20 EGD91837.2 - 4e-12 46.3 0.0 4.9e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD91837.2 - 0.0084 15.4 0.0 0.0089 15.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGD91837.2 - 0.072 13.7 0.0 0.072 13.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family ADH_zinc_N PF00107.26 EGD91838.1 - 1.3e-17 63.9 0.0 3.1e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGD91838.1 - 9.5e-16 59.1 0.0 2.1e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGD91838.1 - 1.1e-06 28.4 0.0 4.8e-06 26.4 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ATP-synt_G PF04718.15 EGD91839.1 - 1.7e-33 115.4 0.1 6.9e-33 113.5 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Glyco_hydro_92 PF07971.12 EGD91841.2 - 5.1e-135 451.0 0.2 6.4e-135 450.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EGD91841.2 - 1e-47 163.0 2.2 1.9e-47 162.2 2.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain MFS_1 PF07690.16 EGD91842.1 - 2.4e-18 66.2 38.6 6.6e-13 48.3 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD91842.1 - 9.8e-15 54.3 23.0 4.9e-14 52.0 23.0 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Asp PF00026.23 EGD91843.1 - 6.5e-05 22.5 0.3 0.0018 17.8 0.0 2.4 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Spore_YtfJ PF09579.10 EGD91843.1 - 0.19 11.9 1.1 0.46 10.7 1.1 1.5 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) Glyco_hydro_31 PF01055.26 EGD91845.2 - 3.8e-168 560.2 0.5 4.9e-168 559.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EGD91845.2 - 1.7e-39 134.6 0.5 3.7e-39 133.5 0.5 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EGD91845.2 - 4.4e-15 55.8 0.1 1.3e-14 54.2 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Abhydrolase_2 PF02230.16 EGD91846.1 - 3.5e-22 79.3 0.0 2.6e-17 63.3 0.0 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EGD91846.1 - 0.0078 15.5 0.1 0.061 12.6 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGD91846.1 - 0.015 14.8 0.1 0.037 13.5 0.1 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGD91846.1 - 0.038 13.6 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Choline_kinase PF01633.20 EGD91847.1 - 1e-59 201.7 0.0 2e-59 200.8 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EGD91847.1 - 7.1e-17 60.8 0.0 1.5e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 EGD91847.1 - 0.00032 20.7 0.1 0.001 19.1 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Mem_trans PF03547.18 EGD91848.2 - 1.2e-14 53.5 9.3 1.4e-14 53.3 9.3 1.0 1 0 0 1 1 1 1 Membrane transport protein Pkinase PF00069.25 EGD91849.1 - 1.8e-53 181.6 0.0 3.4e-51 174.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD91849.1 - 7.6e-32 110.6 0.0 9.2e-31 107.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGD91849.1 - 0.0027 17.1 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGD91849.1 - 0.0042 16.1 0.0 0.0061 15.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGD91849.1 - 0.0048 16.0 0.1 0.0091 15.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EGD91849.1 - 0.16 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pyr_redox_2 PF07992.14 EGD91852.2 - 7.4e-54 183.0 0.4 1.2e-53 182.3 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGD91852.2 - 3.5e-30 104.5 0.1 7.9e-30 103.3 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGD91852.2 - 4.2e-14 52.9 0.1 4.2e-14 52.9 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGD91852.2 - 4.2e-10 39.4 0.9 5.5e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGD91852.2 - 0.015 14.4 0.0 0.036 13.2 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 EGD91852.2 - 0.057 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EGD91852.2 - 1.1 8.3 3.3 0.89 8.6 0.4 2.3 3 1 1 4 4 4 0 Glucose inhibited division protein A ECH_1 PF00378.20 EGD91853.1 - 3.2e-41 141.3 0.0 4.2e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGD91853.1 - 1.8e-25 90.2 0.2 2.4e-25 89.7 0.2 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase tRNA-synt_2b PF00587.25 EGD91854.1 - 6.2e-33 114.3 0.0 1e-32 113.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGD91854.1 - 0.00049 20.2 0.0 0.0029 17.7 0.0 2.2 3 0 0 3 3 3 1 Anticodon binding domain Fungal_trans PF04082.18 EGD91855.2 - 1.2e-25 90.0 0.1 2e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SOGA PF11365.8 EGD91855.2 - 0.11 13.7 0.9 0.25 12.5 0.9 1.6 1 0 0 1 1 1 0 Protein SOGA Spc24 PF08286.11 EGD91855.2 - 1.2 9.4 4.6 8.6 6.7 0.0 2.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Amidohydro_2 PF04909.14 EGD91856.1 - 2.2e-19 70.4 0.0 2.6e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase GP120 PF00516.18 EGD91860.1 - 0.091 11.3 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Envelope glycoprotein GP120 Peptidase_C12 PF01088.21 EGD91861.1 - 3.3e-68 229.6 0.0 5.8e-68 228.8 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EGD91861.1 - 6.4e-08 32.4 0.1 1.4e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases LRR19-TM PF15176.6 EGD91863.2 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain HEAT_EZ PF13513.6 EGD91865.1 - 2.8e-30 104.3 12.4 1.4e-15 57.4 0.0 10.2 7 3 4 11 11 11 5 HEAT-like repeat HEAT PF02985.22 EGD91865.1 - 6.3e-23 78.9 18.3 7.5e-05 22.7 0.0 11.7 14 0 0 14 14 13 3 HEAT repeat HEAT_2 PF13646.6 EGD91865.1 - 4.9e-18 65.3 2.7 0.003 17.9 0.0 8.1 5 3 3 8 8 8 3 HEAT repeats Cnd1 PF12717.7 EGD91865.1 - 2.2e-12 47.3 0.0 0.00056 20.0 0.0 5.9 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGD91865.1 - 1.1e-08 35.5 0.0 0.035 14.7 0.0 4.9 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 EGD91865.1 - 1.7e-08 34.0 6.1 0.42 9.7 0.3 5.4 5 1 0 5 5 5 3 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 EGD91865.1 - 5e-08 32.8 0.6 0.0045 16.6 0.2 6.0 3 3 1 4 4 4 1 CLASP N terminal Xpo1 PF08389.12 EGD91865.1 - 2e-05 24.7 0.1 0.00048 20.2 0.0 3.4 4 1 0 4 4 2 1 Exportin 1-like protein RIX1 PF08167.12 EGD91865.1 - 5.1e-05 23.1 0.8 3.1 7.5 0.0 5.5 5 1 1 6 6 6 1 rRNA processing/ribosome biogenesis IBN_N PF03810.19 EGD91865.1 - 7.8e-05 22.5 0.8 0.012 15.5 0.0 4.2 3 2 1 4 4 4 1 Importin-beta N-terminal domain Sec7_N PF12783.7 EGD91865.1 - 0.00031 20.7 0.3 0.0099 15.8 0.1 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3437 PF11919.8 EGD91865.1 - 0.00056 19.8 0.7 0.16 11.9 0.0 4.7 6 0 0 6 6 5 1 Domain of unknown function (DUF3437) Adaptin_N PF01602.20 EGD91865.1 - 0.00058 18.5 0.5 0.16 10.5 0.0 4.0 3 2 1 4 4 4 1 Adaptin N terminal region Dopey_N PF04118.14 EGD91865.1 - 0.00059 19.0 0.1 0.054 12.6 0.0 2.7 3 0 0 3 3 3 1 Dopey, N-terminal Arm PF00514.23 EGD91865.1 - 0.0011 18.9 7.1 2.1 8.5 0.0 6.3 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EGD91865.1 - 0.0046 17.1 0.0 0.03 14.5 0.0 2.5 2 0 0 2 2 1 1 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 EGD91865.1 - 0.087 12.5 0.0 2.4 7.8 0.0 2.7 3 0 0 3 3 3 0 DNA alkylation repair enzyme HEAT_PBS PF03130.16 EGD91865.1 - 0.19 12.5 4.5 27 5.8 0.0 5.3 7 0 0 7 7 3 0 PBS lyase HEAT-like repeat TAFH PF07531.14 EGD91865.1 - 0.75 9.9 6.6 21 5.3 0.0 5.1 6 0 0 6 6 5 0 NHR1 homology to TAF Syja_N PF02383.18 EGD91866.2 - 1e-61 209.1 0.0 1.8e-61 208.2 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EGD91866.2 - 2.7e-39 133.4 0.0 4.5e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 Inositol phosphatase Mg_trans_NIPA PF05653.14 EGD91867.1 - 4.3e-105 351.0 15.0 5e-105 350.8 15.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EGD91867.1 - 2.7e-06 27.6 31.7 9.1e-05 22.6 8.0 3.3 3 0 0 3 3 3 3 EamA-like transporter family Acyl_transf_3 PF01757.22 EGD91867.1 - 0.00062 18.9 5.2 0.00062 18.9 5.2 2.2 1 1 0 2 2 2 1 Acyltransferase family DUF2420 PF10336.9 EGD91869.1 - 1.5e-18 66.8 0.0 2.6e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 EGD91870.2 - 1.3e-22 80.4 0.0 1.9e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGD91870.2 - 8.7e-07 29.0 0.3 1.5e-06 28.2 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 EGD91870.2 - 0.0022 18.4 0.2 0.0042 17.5 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) FTR1 PF03239.14 EGD91872.1 - 7.7e-83 278.2 9.7 9.6e-83 277.9 9.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Rft-1 PF04506.13 EGD91872.1 - 0.019 13.8 0.7 0.019 13.8 0.7 1.8 2 0 0 2 2 2 0 Rft protein DUF1218 PF06749.12 EGD91872.1 - 2.7 8.6 6.6 5.6 7.5 1.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) FtsX PF02687.21 EGD91872.1 - 8.5 6.9 21.5 0.099 13.1 1.0 3.8 2 1 0 2 2 2 0 FtsX-like permease family Cu-oxidase_2 PF07731.14 EGD91873.1 - 1.7e-47 160.6 5.8 2e-42 144.2 0.9 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGD91873.1 - 9.2e-42 141.8 1.3 5e-38 129.8 0.3 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EGD91873.1 - 1e-38 133.0 2.2 4.2e-34 118.0 0.7 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EGD91873.1 - 0.00017 21.7 0.0 2.7 8.2 0.0 3.6 2 1 0 2 2 2 2 Cupredoxin-like domain C1q PF00386.21 EGD91873.1 - 0.029 14.6 0.0 4.8 7.4 0.2 2.4 2 0 0 2 2 2 0 C1q domain OMPdecase PF00215.24 EGD91874.2 - 4.9e-09 36.1 0.0 1e-06 28.5 0.0 2.4 2 0 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family Cyt-b5 PF00173.28 EGD91876.1 - 2.1e-18 66.2 0.1 2.1e-18 66.2 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EGD91876.1 - 1.6e-12 47.9 16.0 1.6e-12 47.9 16.0 1.9 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 EGD91876.1 - 0.0056 16.9 0.3 0.011 15.9 0.3 1.4 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region MFS_1 PF07690.16 EGD91878.1 - 2.5e-36 125.4 42.1 6.4e-35 120.7 40.8 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGD91878.1 - 4.6e-11 42.3 12.1 4.6e-11 42.3 12.1 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 EGD91878.1 - 0.0028 16.0 1.0 0.0028 16.0 1.0 2.9 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Ac76 PF05814.11 EGD91878.1 - 0.021 14.8 1.0 1.8 8.6 0.2 2.6 2 0 0 2 2 2 0 Orf76 (Ac76) DUF2561 PF10812.8 EGD91878.1 - 0.024 14.7 0.0 0.024 14.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) DUF2721 PF11026.8 EGD91878.1 - 0.035 14.0 0.1 0.035 14.0 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) RRM_1 PF00076.22 EGD91879.2 - 1.8e-05 24.5 0.0 2.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATG16 PF08614.11 EGD91880.1 - 0.0013 19.0 2.8 0.0025 18.1 2.8 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ADIP PF11559.8 EGD91880.1 - 0.083 13.0 2.1 0.14 12.2 2.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding T2SS_PulS_OutS PF09691.10 EGD91880.1 - 0.1 12.7 0.1 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 Type II secretion system pilotin lipoprotein (PulS_OutS) DUF4407 PF14362.6 EGD91880.1 - 0.14 11.5 0.6 0.23 10.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_tran_CTD PF16326.5 EGD91880.1 - 0.39 11.0 7.7 26 5.2 8.0 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain MscS_porin PF12795.7 EGD91880.1 - 0.44 10.0 9.7 0.71 9.4 9.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain TRAF_BIRC3_bd PF16673.5 EGD91880.1 - 0.72 9.7 3.0 6.1 6.7 3.0 2.1 1 1 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Metal_resist PF13801.6 EGD91880.1 - 0.86 9.8 10.7 0.12 12.5 5.8 2.1 2 0 0 2 2 2 0 Heavy-metal resistance GreA_GreB_N PF03449.15 EGD91880.1 - 1.1 9.4 4.2 38 4.5 4.2 2.4 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal GrpE PF01025.19 EGD91880.1 - 1.2 8.8 5.9 1.8 8.2 0.1 2.9 2 1 1 3 3 3 0 GrpE BST2 PF16716.5 EGD91880.1 - 2.3 8.9 5.7 16 6.1 0.5 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 PKcGMP_CC PF16808.5 EGD91880.1 - 4.7 7.1 8.3 5.2 7.0 1.1 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Serglycin PF04360.12 EGD91880.1 - 7.8 6.4 9.8 0.15 12.0 1.5 2.1 2 0 0 2 2 2 0 Serglycin DUF5320 PF17253.2 EGD91880.1 - 9.2 7.4 16.9 4.2 8.5 0.1 3.9 2 2 1 4 4 4 0 Family of unknown function (DUF5320) PP2C PF00481.21 EGD91882.1 - 5.8e-32 111.3 0.0 5e-26 91.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGD91882.1 - 0.0079 15.9 0.1 0.029 14.0 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C CDP-OH_P_transf PF01066.21 EGD91883.1 - 1.8e-12 47.8 0.3 1.8e-12 47.8 0.3 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Med3 PF11593.8 EGD91883.1 - 0.37 9.9 5.2 0.53 9.4 5.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Methyltransf_23 PF13489.6 EGD91884.2 - 2e-20 73.3 0.0 3.3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD91884.2 - 6e-10 39.7 0.0 1.6e-09 38.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD91884.2 - 1.1e-08 35.1 0.0 9.1e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD91884.2 - 2.6e-07 31.2 0.0 6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD91884.2 - 4.4e-06 27.3 0.0 3.3e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGD91884.2 - 0.00073 19.1 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EGD91884.2 - 0.0086 16.2 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EGD91884.2 - 0.055 13.2 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 EGD91884.2 - 0.057 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EGD91884.2 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Iso_dh PF00180.20 EGD91886.2 - 3.6e-97 325.6 0.0 4.1e-97 325.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AAA_lid_3 PF17862.1 EGD91886.2 - 0.025 14.4 0.0 0.076 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA+ lid domain ANAPC10 PF03256.16 EGD91887.1 - 3.7e-45 153.8 0.0 5.5e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DNA_pol_phi PF04931.13 EGD91887.1 - 0.084 11.0 31.0 0.0084 14.3 19.2 2.0 2 0 0 2 2 2 0 DNA polymerase phi Raftlin PF15250.6 EGD91887.1 - 1.9 7.1 4.1 3.7 6.2 4.1 1.4 1 0 0 1 1 1 0 Raftlin FYDLN_acid PF09538.10 EGD91887.1 - 3 8.6 22.8 5.4 7.7 2.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) BUD22 PF09073.10 EGD91887.1 - 3.2 7.0 22.0 0.22 10.8 11.3 2.0 2 0 0 2 2 2 0 BUD22 CPSF100_C PF13299.6 EGD91887.1 - 5.9 7.1 6.9 4.7 7.4 4.2 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal COPI_C PF06957.11 EGD91887.1 - 6.5 5.4 9.8 12 4.6 9.8 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus E1-E2_ATPase PF00122.20 EGD91888.1 - 1.6e-37 128.8 16.3 4.2e-31 107.9 0.0 3.8 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGD91888.1 - 1.1e-25 90.5 7.6 1.1e-25 90.5 7.6 2.9 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGD91888.1 - 9e-19 68.6 0.0 1e-16 61.9 0.0 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGD91888.1 - 7e-17 60.9 0.0 1.4e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGD91888.1 - 1.6e-15 56.9 0.0 3.3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGD91888.1 - 0.00013 21.8 0.4 0.0026 17.5 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 EGD91888.1 - 0.0034 17.3 0.6 0.0082 16.0 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) Wzy_C PF04932.15 EGD91888.1 - 0.34 10.5 0.0 0.34 10.5 0.0 2.6 3 0 0 3 3 3 0 O-Antigen ligase PS_Dcarbxylase PF02666.15 EGD91889.1 - 2e-75 252.8 0.0 7.3e-75 250.9 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase PT PF04886.12 EGD91890.2 - 0.022 14.3 3.1 0.022 14.3 3.1 3.1 3 0 0 3 3 3 0 PT repeat His_Phos_1 PF00300.22 EGD91891.2 - 0.00066 19.4 0.0 0.002 17.9 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_S8 PF00410.19 EGD91892.1 - 8.6e-22 77.4 0.2 1.3e-21 76.8 0.2 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Metallophos PF00149.28 EGD91893.1 - 9.5e-12 45.8 0.2 1.5e-11 45.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGD91893.1 - 4.1e-06 27.1 0.0 6.5e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ANAPC4 PF12896.7 EGD91894.2 - 4.8e-63 212.4 0.7 6.3e-63 212.0 0.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF374 PF04028.13 EGD91894.2 - 0.1 12.1 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF374) HEAT PF02985.22 EGD91895.1 - 8.6e-14 50.5 17.9 0.00011 22.1 0.0 8.7 10 1 0 10 10 9 2 HEAT repeat HEAT_EZ PF13513.6 EGD91895.1 - 5.1e-11 42.8 3.8 1.3e-06 28.7 0.0 6.3 6 0 0 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 EGD91895.1 - 1.7e-09 37.9 7.3 0.00029 21.2 0.1 6.2 3 2 3 6 6 6 3 HEAT repeats CLASP_N PF12348.8 EGD91895.1 - 6.3e-07 29.2 1.3 0.029 13.9 0.0 4.0 4 0 0 4 4 4 2 CLASP N terminal IBN_N PF03810.19 EGD91895.1 - 4.8e-05 23.2 2.3 0.04 13.8 0.2 3.7 3 0 0 3 3 3 2 Importin-beta N-terminal domain DUF3385 PF11865.8 EGD91895.1 - 0.00015 21.7 1.5 3.3 7.6 0.5 4.1 4 0 0 4 4 4 2 Domain of unknown function (DUF3385) MMS19_N PF14500.6 EGD91895.1 - 0.0092 15.6 0.7 2.1 7.9 0.8 2.8 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II Cse1 PF08506.10 EGD91895.1 - 0.01 14.7 0.0 1.9 7.2 0.0 3.2 3 0 0 3 3 3 0 Cse1 Arm PF00514.23 EGD91895.1 - 0.018 15.0 4.0 24 5.1 0.2 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 EGD91895.1 - 0.062 13.2 0.3 2.2 8.2 0.0 2.8 1 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal NUC173 PF08161.12 EGD91895.1 - 0.38 10.4 3.8 63 3.1 0.0 4.0 4 1 0 5 5 5 0 NUC173 domain ANAPC4 PF12896.7 EGD91896.2 - 1.1e-17 64.2 0.1 1.9e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 VWA PF00092.28 EGD91899.1 - 1.9e-07 31.5 0.0 2.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGD91899.1 - 0.00052 20.6 0.0 0.0029 18.2 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain Tannase PF07519.11 EGD91900.1 - 2.3e-96 323.5 0.0 2.8e-96 323.3 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 EGD91900.1 - 0.0071 16.0 0.0 0.023 14.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGD91900.1 - 0.12 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Methyltransf_16 PF10294.9 EGD91903.1 - 2.9e-22 79.2 0.0 4.7e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase APH PF01636.23 EGD91904.1 - 5.2e-18 65.9 0.0 6.8e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD91904.1 - 0.0032 17.1 0.0 0.0061 16.2 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EGD91904.1 - 0.012 15.2 0.0 3.9 7.0 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.14 EGD91904.1 - 0.064 12.4 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Pkinase PF00069.25 EGD91904.1 - 0.17 11.2 0.0 3.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Zn_clus PF00172.18 EGD91906.1 - 6.7e-09 35.7 9.6 1.2e-08 34.9 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGD91906.1 - 1.2e-07 30.9 4.8 1.2e-06 27.6 0.4 3.0 2 1 1 3 3 3 2 Fungal specific transcription factor domain VPS28 PF03997.12 EGD91907.2 - 3.2e-45 154.1 0.1 3.5e-45 154.0 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.13 EGD91908.1 - 3.7e-129 430.3 0.3 1e-128 428.8 0.0 1.9 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 EGD91908.1 - 0.00041 18.7 0.3 0.00041 18.7 0.3 3.1 2 1 1 3 3 3 2 Nop14-like family bMG10 PF17973.1 EGD91908.1 - 0.11 12.7 0.6 0.28 11.4 0.6 1.7 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain Piwi PF02171.17 EGD91909.2 - 3.4e-64 217.0 0.0 5.6e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EGD91909.2 - 1.4e-18 67.8 0.3 4.1e-18 66.3 0.3 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EGD91909.2 - 1.5e-15 56.6 1.1 2.9e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 EGD91909.2 - 4.1e-09 36.3 0.1 8.7e-08 32.1 0.0 3.0 3 0 0 3 3 3 1 PAZ domain ArgoL2 PF16488.5 EGD91909.2 - 1.6e-06 28.4 0.0 4.3e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain MoaC PF01967.21 EGD91910.1 - 3.7e-44 150.1 0.2 5.8e-44 149.5 0.2 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EGD91910.1 - 4.9e-37 126.7 0.0 5.7e-36 123.3 0.0 2.2 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EGD91910.1 - 6.7e-28 98.2 0.1 1.5e-27 97.0 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EGD91910.1 - 8.3e-05 22.9 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain CARMIL_C PF16000.5 EGD91910.1 - 0.092 12.4 2.3 0.17 11.5 2.3 1.3 1 0 0 1 1 1 0 CARMIL C-terminus RVT_1 PF00078.27 EGD91911.2 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AA_permease PF00324.21 EGD91912.1 - 1.7e-142 475.4 36.4 2.1e-142 475.1 36.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGD91912.1 - 8.8e-36 123.6 38.5 1.1e-35 123.4 38.5 1.1 1 0 0 1 1 1 1 Amino acid permease ABC_tran PF00005.27 EGD91913.2 - 2.3e-35 122.1 0.3 2.8e-23 82.9 0.0 3.2 3 1 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EGD91913.2 - 1.7e-09 37.6 2.0 5.1e-09 36.0 2.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGD91913.2 - 8.5e-08 32.3 3.8 0.092 12.5 0.1 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGD91913.2 - 2.3e-07 30.5 0.3 0.089 12.2 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGD91913.2 - 0.025 14.7 0.1 0.25 11.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase CCDC-167 PF15188.6 EGD91913.2 - 0.73 10.2 3.1 1.2 9.5 0.3 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 AAA_23 PF13476.6 EGD91913.2 - 0.74 10.3 0.0 0.74 10.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain 2OG-FeII_Oxy_3 PF13640.6 EGD91914.2 - 1e-07 32.8 0.0 2.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ANAPC4_WD40 PF12894.7 EGD91915.2 - 5.6e-08 33.0 0.1 0.00085 19.6 0.0 3.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGD91915.2 - 8.3e-07 29.6 4.1 0.021 15.7 0.1 4.4 3 1 0 3 3 3 2 WD domain, G-beta repeat IKI3 PF04762.12 EGD91915.2 - 2.6e-06 25.8 0.0 4.5e-06 25.0 0.0 1.2 1 1 0 1 1 1 1 IKI3 family PD40 PF07676.12 EGD91915.2 - 0.11 12.4 1.7 0.59 10.1 0.1 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ribosomal_S25 PF03297.15 EGD91916.2 - 9.7e-37 125.2 5.2 1.1e-36 125.1 5.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.12 EGD91916.2 - 0.0049 16.6 0.1 0.0072 16.1 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 EGD91916.2 - 0.02 15.3 0.1 0.026 14.8 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_11 PF08279.12 EGD91916.2 - 0.023 14.6 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 EGD91916.2 - 0.047 13.3 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EGD91916.2 - 0.077 12.9 0.2 0.1 12.5 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 EGD91916.2 - 0.086 12.7 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 MarR family Cyt-b5 PF00173.28 EGD91917.1 - 5.6e-10 39.2 0.0 1.2e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gtr1_RagA PF04670.12 EGD91918.2 - 2.1e-56 190.9 0.6 3.2e-56 190.3 0.6 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EGD91918.2 - 0.018 14.9 0.2 0.027 14.2 0.2 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Arf PF00025.21 EGD91918.2 - 0.033 13.6 0.1 0.062 12.8 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Pkinase PF00069.25 EGD91919.1 - 5.1e-23 81.8 0.0 6.4e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD91919.1 - 0.00043 19.6 0.0 0.00079 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGD91919.1 - 0.0014 18.6 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family His_Phos_2 PF00328.22 EGD91920.1 - 1.9e-17 63.7 0.0 5.4e-16 58.9 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lactamase_B_4 PF13691.6 EGD91921.1 - 2.7e-27 94.2 0.5 4.7e-26 90.3 0.1 2.6 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EGD91921.1 - 1e-13 51.3 0.3 3.9e-06 26.5 0.0 2.4 1 1 1 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGD91921.1 - 8.6e-05 22.6 0.1 0.00021 21.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily NAD_binding_10 PF13460.6 EGD91922.1 - 7.3e-19 68.4 0.0 2e-18 67.0 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGD91922.1 - 0.0011 18.4 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family LAM_C PF12544.8 EGD91922.1 - 0.16 12.2 0.4 1.1 9.5 0.0 2.2 3 0 0 3 3 3 0 Lysine-2,3-aminomutase Methyltransf_25 PF13649.6 EGD91923.1 - 5.2e-18 65.5 0.0 2.5e-17 63.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD91923.1 - 2e-16 60.4 0.0 2.2e-14 53.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD91923.1 - 1.8e-15 57.2 0.0 5.6e-14 52.3 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD91923.1 - 3e-15 56.8 0.0 2.2e-09 37.9 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EGD91923.1 - 2e-14 53.6 0.0 1.5e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain CMAS PF02353.20 EGD91923.1 - 6.3e-09 35.5 0.0 1.1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 EGD91923.1 - 1.4e-06 28.1 0.0 0.00011 21.9 0.0 2.3 2 0 0 2 2 2 1 Nodulation protein S (NodS) Pox_MCEL PF03291.16 EGD91923.1 - 1.4e-05 24.4 0.0 0.00019 20.6 0.0 2.4 1 1 0 1 1 1 1 mRNA capping enzyme MTS PF05175.14 EGD91923.1 - 0.00014 21.4 0.0 0.00056 19.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.12 EGD91923.1 - 0.00016 21.3 0.0 0.0023 17.6 0.0 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW CheR PF01739.18 EGD91923.1 - 0.00028 20.4 0.1 0.32 10.5 0.0 2.5 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain TPMT PF05724.11 EGD91923.1 - 0.00087 19.0 0.0 0.0027 17.4 0.0 1.9 2 1 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 EGD91923.1 - 0.0067 15.8 0.0 0.029 13.7 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 EGD91923.1 - 0.0078 15.2 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) SBD_N PF07005.11 EGD91923.1 - 0.014 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-binding N-terminal domain PCMT PF01135.19 EGD91923.1 - 0.016 15.0 0.0 0.043 13.6 0.0 1.8 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 EGD91923.1 - 0.016 14.6 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 EGD91923.1 - 0.038 14.0 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.13 EGD91923.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) bZIP_1 PF00170.21 EGD91924.1 - 2.7e-08 33.8 9.3 2.7e-08 33.8 9.3 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGD91924.1 - 0.00066 19.7 11.1 0.00066 19.7 11.1 2.7 2 1 0 2 2 2 1 Basic region leucine zipper Het-C PF07217.11 EGD91924.1 - 1.4 7.3 11.0 13 4.2 0.0 2.4 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C Dus PF01207.17 EGD91925.2 - 7.5e-59 199.3 0.0 1.8e-58 198.1 0.0 1.6 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EGD91925.2 - 0.014 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase APH PF01636.23 EGD91926.1 - 1.3e-10 41.6 0.2 1.3e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGD91926.1 - 0.052 12.9 0.1 0.09 12.1 0.1 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 EGD91926.1 - 0.071 12.0 0.1 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) SpoIID PF08486.10 EGD91926.1 - 0.2 12.3 0.0 0.83 10.2 0.0 1.9 2 0 0 2 2 2 0 Stage II sporulation protein Macro PF01661.21 EGD91928.1 - 2.2e-11 43.8 0.0 1.6e-05 24.9 0.0 2.4 2 1 0 2 2 2 2 Macro domain Corona_nucleoca PF00937.18 EGD91928.1 - 0.038 13.0 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FoP_duplication PF13865.6 EGD91928.1 - 7.4 7.2 8.9 12 6.5 8.9 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 CENP-X PF09415.10 EGD91929.1 - 2.1e-23 82.4 0.3 4.1e-23 81.5 0.3 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Mis12 PF05859.12 EGD91931.1 - 1.1e-47 161.4 0.0 2e-47 160.7 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein ATG16 PF08614.11 EGD91931.1 - 0.041 14.1 1.2 0.46 10.7 0.4 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) MitoNEET_N PF10660.9 EGD91931.1 - 0.09 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Trans_reg_C PF00486.28 EGD91932.1 - 0.0087 16.1 0.5 0.056 13.5 0.1 2.2 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Pheromone PF08015.11 EGD91934.2 - 2.4 9.3 5.4 3.3 8.8 2.8 2.3 1 1 1 2 2 2 0 Fungal mating-type pheromone Herpes_DNAp_acc PF04929.12 EGD91934.2 - 4.3 6.2 5.8 7.2 5.5 5.8 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Acetyltransf_3 PF13302.7 EGD91935.1 - 2e-30 106.2 0.0 2.5e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGD91935.1 - 0.091 13.0 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EGD91935.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Methyltransf_3 PF01596.17 EGD91936.2 - 1e-24 86.9 0.0 1.9e-24 86.1 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGD91936.2 - 3.2e-10 41.0 0.0 7.8e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGD91936.2 - 1.2e-09 38.3 0.0 1.7e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGD91936.2 - 2.2e-08 34.0 0.0 2.4e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGD91936.2 - 1.6e-07 32.0 0.0 2.9e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGD91936.2 - 0.00065 19.1 0.0 0.00078 18.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EGD91936.2 - 0.00068 20.2 0.1 0.003 18.2 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGD91936.2 - 0.001 18.6 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 EGD91936.2 - 0.0087 16.8 0.0 0.018 15.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EGD91936.2 - 0.027 14.2 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_15 PF09445.10 EGD91936.2 - 0.19 11.3 0.0 0.28 10.8 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Spt20 PF12090.8 EGD91937.2 - 9.2e-36 123.6 10.1 9.2e-36 123.6 10.1 7.4 4 3 0 4 4 4 2 Spt20 family Fungal_lectin_2 PF18647.1 EGD91938.2 - 5.9e-36 123.0 0.4 1.3e-35 121.9 0.4 1.6 1 0 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 EGD91938.2 - 2.8e-12 47.4 0.0 5.4e-12 46.5 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGD91938.2 - 6.1e-06 26.4 0.0 1.8e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase DUF515 PF04415.12 EGD91940.1 - 0.12 10.8 4.6 0.13 10.7 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) BES1_N PF05687.13 EGD91940.1 - 3.4 8.1 8.4 4.4 7.7 8.4 1.2 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Hexapep PF00132.24 EGD91944.1 - 2.2e-06 27.2 2.8 0.022 14.5 0.3 3.7 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EGD91944.1 - 6.5e-06 25.3 0.1 1.2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.23 EGD91944.1 - 0.00077 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 EGD91944.1 - 0.011 13.9 0.2 0.016 13.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 EGD91944.1 - 0.034 14.5 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Serglycin PF04360.12 EGD91949.2 - 0.0062 16.5 4.2 0.0062 16.5 4.2 2.5 3 0 0 3 3 3 1 Serglycin Ribosomal_L11_N PF03946.14 EGD91953.1 - 0.0023 17.7 0.5 0.0083 15.9 0.5 2.0 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain ELO PF01151.18 EGD91954.1 - 6.7e-39 133.9 2.9 8.4e-39 133.6 2.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4672 PF15716.5 EGD91954.1 - 0.35 10.5 3.1 0.83 9.2 3.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) DHHC PF01529.20 EGD91954.1 - 2 8.5 5.0 32 4.6 0.0 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2072 PF09845.9 EGD91954.1 - 3.7 7.8 5.0 10 6.4 4.9 1.8 1 1 0 1 1 1 0 Zn-ribbon containing protein Fumarate_red_C PF02300.17 EGD91955.2 - 0.1 12.7 0.6 0.15 12.1 0.6 1.2 1 0 0 1 1 1 0 Fumarate reductase subunit C Fungal_trans_2 PF11951.8 EGD91955.2 - 0.77 8.5 4.5 1.2 7.9 4.5 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD91957.1 - 6e-09 35.9 8.8 1.1e-08 35.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGD91957.1 - 5.5e-05 22.2 9.5 8.5e-05 21.5 9.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fumarate_red_C PF02300.17 EGD91957.1 - 0.079 13.0 1.7 0.3 11.2 0.8 2.3 1 1 1 2 2 2 0 Fumarate reductase subunit C APH PF01636.23 EGD91961.1 - 1.8e-14 54.3 0.2 1.1e-13 51.7 0.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGD91961.1 - 0.00011 21.9 0.0 0.00027 20.6 0.1 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase BNR PF02012.20 EGD91962.1 - 0.035 14.1 1.1 0.13 12.4 0.2 2.5 2 0 0 2 2 2 0 BNR/Asp-box repeat Mo-co_dimer PF03404.16 EGD91962.1 - 0.055 13.5 0.1 0.08 13.0 0.1 1.2 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain TruD PF01142.18 EGD91963.1 - 3.6e-59 200.7 0.0 5.8e-55 186.8 0.0 3.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Cupin_1 PF00190.22 EGD91964.1 - 1.1e-37 128.9 0.0 2.8e-18 66.0 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EGD91964.1 - 1.4e-20 72.7 1.4 1.1e-09 37.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EGD91964.1 - 1e-05 25.1 0.1 0.016 14.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EGD91964.1 - 0.00048 20.0 0.8 0.032 14.1 0.2 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain 3-HAO PF06052.12 EGD91964.1 - 0.04 13.5 0.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.12 EGD91964.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Acetyltransf_10 PF13673.7 EGD91966.1 - 0.0006 19.8 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGD91966.1 - 0.026 14.9 0.0 0.067 13.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGD91966.1 - 0.066 13.5 0.0 0.1 12.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family RPE65 PF03055.15 EGD91968.1 - 1.4e-112 377.3 0.0 1.6e-112 377.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF2293 PF10056.9 EGD91969.1 - 2.2e-28 98.3 1.2 3.4e-28 97.7 0.5 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) DUF3754 PF12576.8 EGD91969.1 - 0.16 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) BNIP2 PF12496.8 EGD91971.2 - 1.8 9.0 6.4 0.54 10.7 0.2 2.9 3 1 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 NUP50 PF08911.11 EGD91971.2 - 8 7.2 9.1 0.39 11.4 1.5 2.9 3 0 0 3 3 3 0 NUP50 (Nucleoporin 50 kDa) Mtc PF03820.17 EGD91972.1 - 2.3e-118 394.8 0.0 2.6e-118 394.6 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.25 EGD91973.1 - 5.6e-49 166.9 0.0 3.1e-48 164.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD91973.1 - 1.6e-19 70.2 0.0 5e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DPBB_1 PF03330.18 EGD91974.1 - 0.0016 18.7 0.3 0.003 17.8 0.3 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EGD91974.1 - 0.0094 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Barwin family FAD_binding_4 PF01565.23 EGD91975.2 - 1.8e-21 76.3 0.9 1.8e-21 76.3 0.9 1.5 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EGD91975.2 - 2.7e-13 49.8 0.0 6.6e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like TAF4 PF05236.14 EGD91977.1 - 1.3e-25 90.7 6.2 1.4e-24 87.3 6.2 2.4 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Kdo PF06293.14 EGD91978.1 - 3.1e-07 30.0 0.2 6.7e-07 28.9 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.14 EGD91978.1 - 0.034 12.5 13.4 0.065 11.5 13.4 1.4 1 0 0 1 1 1 0 CDC45-like protein APH PF01636.23 EGD91978.1 - 0.036 14.0 0.1 0.036 14.0 0.1 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGD91978.1 - 0.069 12.5 0.4 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain AsmA PF05170.14 EGD91978.1 - 0.23 10.2 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 AsmA family MAP7 PF05672.11 EGD91978.1 - 0.52 10.0 49.8 1.3 8.7 49.8 1.6 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Spore_coat_CotO PF14153.6 EGD91978.1 - 4.8 7.1 23.6 23 4.8 19.3 2.3 2 0 0 2 2 2 0 Spore coat protein CotO ALMT PF11744.8 EGD91978.1 - 5 5.8 10.6 7.7 5.2 10.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF913 PF06025.12 EGD91978.1 - 5.5 5.9 7.7 11 4.8 7.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CiPC PF15800.5 EGD91978.1 - 6.5 6.4 23.1 9.9 5.8 5.0 3.1 3 0 0 3 3 3 0 Clock interacting protein circadian OATP PF03137.20 EGD91978.1 - 6.9 4.8 4.8 11 4.2 4.8 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S41 PF03572.18 EGD91979.2 - 8.2e-08 32.0 0.0 2.5e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 DUF1659 PF07872.11 EGD91979.2 - 0.031 13.9 0.2 0.063 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) DUF677 PF05055.12 EGD91983.1 - 0.23 10.3 3.7 0.31 9.9 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Peptidase_S8 PF00082.22 EGD91985.1 - 2e-33 115.9 14.9 6.1e-33 114.3 14.9 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGD91985.1 - 3.1e-17 63.0 0.1 9.6e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase inhibitor I9 AAT PF03417.16 EGD91986.1 - 3.7e-38 131.5 0.0 4.5e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 2OG-FeII_Oxy PF03171.20 EGD91987.1 - 1.3e-13 51.2 0.4 3.3e-13 50.0 0.0 1.8 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGD91987.1 - 3e-13 50.6 0.0 4.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal AMP-binding PF00501.28 EGD91988.1 - 2.9e-246 816.8 0.0 1.4e-87 294.0 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EGD91988.1 - 4.6e-243 806.9 9.9 1.9e-90 303.8 3.1 5.1 5 0 0 5 5 5 4 Condensation domain PP-binding PF00550.25 EGD91988.1 - 1.1e-52 176.2 0.6 2.8e-17 62.8 0.1 4.3 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGD91988.1 - 1e-26 93.7 0.0 3.9e-10 40.6 0.0 3.8 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 EGD91988.1 - 4.3e-26 92.4 0.0 1e-25 91.2 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EGD91988.1 - 0.0012 19.5 1.2 0.02 15.5 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family AATase PF07247.12 EGD91988.1 - 0.011 14.3 1.7 0.099 11.2 0.1 2.7 2 1 1 3 3 3 0 Alcohol acetyltransferase GST_N PF02798.20 EGD91992.1 - 7.2e-12 45.5 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGD91992.1 - 1.7e-09 38.0 0.1 8.5e-09 35.7 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGD91992.1 - 2.9e-07 30.7 0.0 4.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGD91992.1 - 7e-07 29.4 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGD91992.1 - 0.0002 21.5 0.0 0.00032 20.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGD91992.1 - 0.00039 20.4 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGD91992.1 - 0.13 12.8 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BTB_2 PF02214.22 EGD91993.1 - 6.9e-09 35.9 0.1 2.2e-05 24.7 0.0 2.6 3 0 0 3 3 3 2 BTB/POZ domain BTB PF00651.31 EGD91993.1 - 0.011 15.9 0.0 0.071 13.3 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain FYVE PF01363.21 EGD91994.1 - 2.1e-14 53.4 5.5 3.2e-14 52.8 5.5 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 EGD91994.1 - 0.066 13.4 9.3 0.14 12.3 9.3 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger Acetyltransf_1 PF00583.25 EGD91995.2 - 9.6e-11 41.9 0.0 1.3e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGD91995.2 - 1.3e-10 41.2 0.0 1.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGD91995.2 - 4.1e-10 39.9 0.0 6.6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 EGD91995.2 - 2.2e-07 31.5 0.0 3.9e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGD91995.2 - 1.7e-05 24.8 0.1 3.2e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EGD91995.2 - 4e-05 24.3 0.0 5.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGD91995.2 - 0.00033 20.6 0.0 0.00093 19.1 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGD91995.2 - 0.0035 17.4 0.1 0.006 16.7 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGD91995.2 - 0.05 13.1 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Methyltr_RsmB-F PF01189.17 EGD91996.1 - 2e-18 66.8 0.0 1.9e-10 40.8 0.0 2.5 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F NDUF_B4 PF07225.12 EGD91997.2 - 5.7e-05 23.0 0.0 6.2e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Atthog PF18800.1 EGD91997.2 - 0.088 12.7 0.0 0.089 12.7 0.0 1.1 1 0 0 1 1 1 0 Attenuator of Hedgehog SAP18 PF06487.12 EGD91998.1 - 3.9e-50 169.7 0.0 4.9e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.15 EGD91999.1 - 2.3e-55 186.6 0.0 2.3e-55 186.6 0.0 2.0 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EGD91999.1 - 4.1e-12 45.4 2.5 4.1e-12 45.4 2.5 2.9 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.10 EGD91999.1 - 0.98 8.7 23.4 1.7 8.0 23.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MAJIN PF15077.6 EGD91999.1 - 7.6 6.2 10.4 13 5.5 10.4 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein DEAD PF00270.29 EGD92000.1 - 2.2e-35 122.0 0.0 1.8e-17 63.7 0.0 2.6 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD92000.1 - 8.4e-19 68.0 0.0 5.5e-18 65.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD92000.1 - 3.1e-07 30.5 0.0 1.5e-06 28.3 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3833 PF12915.7 EGD92000.1 - 0.062 12.9 0.6 0.63 9.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3833) Macoilin PF09726.9 EGD92000.1 - 0.17 10.4 18.4 0.038 12.6 3.5 2.1 2 0 0 2 2 2 0 Macoilin family ANAPC1 PF12859.7 EGD92000.1 - 0.54 10.8 6.2 2.2 8.9 6.2 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Glycos_transf_1 PF00534.20 EGD92001.2 - 4.2e-26 91.5 0.0 6e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGD92001.2 - 2.8e-23 82.8 0.0 4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGD92001.2 - 0.0013 19.1 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Arf PF00025.21 EGD92002.2 - 5.2e-39 133.5 0.0 8.2e-26 90.5 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGD92002.2 - 2e-12 47.4 0.0 6.2e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGD92002.2 - 8.8e-11 41.5 0.0 5.8e-05 22.4 0.0 2.8 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGD92002.2 - 1e-07 31.7 0.0 0.00048 19.8 0.0 2.3 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.23 EGD92002.2 - 2.9e-07 30.5 0.0 2.4e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGD92002.2 - 8.7e-07 28.5 0.0 9.6e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGD92002.2 - 1.1e-05 24.9 0.1 6.9e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGD92002.2 - 3e-05 23.6 0.0 0.00083 19.0 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGD92002.2 - 0.033 13.9 0.0 0.097 12.4 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EGD92002.2 - 0.034 13.7 0.0 0.078 12.5 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 EGD92002.2 - 0.097 12.4 0.0 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 EGD92004.2 - 3.7e-21 75.7 0.0 2e-09 37.2 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD92004.2 - 1.9e-09 37.2 0.0 0.00081 18.7 0.1 3.8 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EGD92004.2 - 0.017 14.5 0.1 20 4.4 0.0 3.0 3 0 0 3 3 3 0 Kinase-like APH PF01636.23 EGD92004.2 - 0.054 13.4 0.2 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pyr_redox_3 PF13738.6 EGD92005.2 - 0.00046 19.5 0.0 0.00067 19.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF983 PF06170.12 EGD92007.1 - 3.6 8.1 5.7 36 4.8 3.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Kelch_5 PF13854.6 EGD92009.1 - 1.7e-11 43.9 5.7 9.7e-11 41.4 0.4 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 EGD92009.1 - 2.3e-05 24.3 1.8 0.002 18.1 0.1 4.0 2 2 1 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.25 EGD92009.1 - 5.8e-05 22.6 5.2 0.1 12.2 0.3 4.2 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EGD92009.1 - 7.7e-05 22.9 3.4 0.0016 18.7 0.1 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EGD92009.1 - 0.0051 17.1 4.3 0.022 15.1 0.1 3.7 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 EGD92009.1 - 0.01 15.8 0.4 9.3 6.4 0.1 4.2 4 0 0 4 4 4 0 Kelch motif DUF1658 PF07871.11 EGD92009.1 - 0.75 9.8 3.8 2.2 8.4 3.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) Aldo_ket_red PF00248.21 EGD92010.1 - 2.4e-64 217.3 0.0 2.8e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FA_hydroxylase PF04116.13 EGD92011.1 - 6.7e-23 81.5 13.4 6.7e-23 81.5 13.4 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily UNC-79 PF14776.6 EGD92011.1 - 0.03 13.1 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 BCS1_N PF08740.11 EGD92014.1 - 1.1e-48 165.7 1.1 4.7e-48 163.7 1.5 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 EGD92014.1 - 8.8e-17 61.8 0.0 3.8e-08 33.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGD92014.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGD92014.1 - 0.034 14.5 0.1 0.093 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EGD92014.1 - 0.054 14.0 0.6 0.24 12.0 0.0 2.4 3 1 0 3 3 3 0 AAA domain ATPase PF06745.13 EGD92014.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC Polyoma_lg_T_C PF06431.11 EGD92014.1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus Fungal_trans PF04082.18 EGD92015.2 - 1e-15 57.5 0.1 1.7e-15 56.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SRP19 PF01922.17 EGD92016.1 - 3.3e-33 114.5 0.1 1e-32 112.9 0.0 1.8 2 0 0 2 2 2 1 SRP19 protein PG_binding_1 PF01471.18 EGD92016.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative peptidoglycan binding domain TCTP PF00838.17 EGD92017.2 - 6.1e-13 49.5 0.2 7.1e-13 49.2 0.2 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein GMC_oxred_C PF05199.13 EGD92018.2 - 7.4e-30 104.4 0.2 1.5e-29 103.3 0.2 1.4 1 1 0 1 1 1 1 GMC oxidoreductase Urb2 PF10441.9 EGD92019.2 - 2.3e-64 217.1 0.2 1.6e-63 214.3 0.0 2.4 2 0 0 2 2 2 1 Urb2/Npa2 family hnRNP_Q_AcD PF18360.1 EGD92019.2 - 0.085 12.8 0.1 4.9 7.2 0.0 2.7 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Med22 PF06179.12 EGD92019.2 - 0.25 11.6 1.2 2.2 8.5 0.1 3.0 2 1 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex DUF543 PF04418.12 EGD92020.1 - 1.4e-27 95.4 0.0 1.7e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Copper-fist PF00649.18 EGD92021.1 - 1.2e-17 63.1 0.4 1.2e-17 63.1 0.4 2.0 2 0 0 2 2 2 1 Copper fist DNA binding domain SUIM_assoc PF16619.5 EGD92021.1 - 0.012 15.7 3.0 0.012 15.7 3.0 2.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Metallothio_2 PF01439.18 EGD92021.1 - 0.14 13.0 22.8 0.36 11.8 8.5 3.7 3 0 0 3 3 3 0 Metallothionein GST_N_4 PF17172.4 EGD92022.1 - 1.1e-19 71.0 0.0 4.6e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EGD92022.1 - 3.5e-19 68.3 0.1 6.7e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EGD92022.1 - 6.6e-11 42.6 0.0 1.5e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 EGD92022.1 - 2.1e-05 24.8 0.2 6.3e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 EGD92022.1 - 0.00071 19.5 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pheromone PF08015.11 EGD92022.1 - 0.32 12.1 6.4 1.1 10.4 6.4 1.9 1 0 0 1 1 1 0 Fungal mating-type pheromone Methyltransf_25 PF13649.6 EGD92023.1 - 1.8e-16 60.6 0.0 3.3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGD92023.1 - 2.8e-15 56.7 0.0 5.1e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGD92023.1 - 2.8e-13 49.9 0.0 3.6e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGD92023.1 - 5.7e-13 49.4 0.0 9.4e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGD92023.1 - 4.1e-11 43.0 0.0 5.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGD92023.1 - 5.2e-07 29.4 0.0 4.1e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EGD92023.1 - 2.7e-06 26.9 0.0 4.2e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EGD92023.1 - 0.00016 21.2 0.0 0.00078 19.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 EGD92023.1 - 0.00052 19.4 0.0 0.00067 19.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EGD92023.1 - 0.0024 17.6 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ADH_zinc_N PF00107.26 EGD92023.1 - 0.01 15.8 0.0 0.041 13.9 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF938 PF06080.12 EGD92023.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) TehB PF03848.14 EGD92023.1 - 0.045 13.2 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB DOT1 PF08123.13 EGD92023.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 GidB PF02527.15 EGD92023.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.6 EGD92023.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_7 PF03492.15 EGD92023.1 - 0.16 11.2 0.0 0.33 10.1 0.0 1.5 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase CDC14 PF08045.11 EGD92024.1 - 2.8e-131 436.8 0.0 3.2e-131 436.6 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component TOH_N PF12549.8 EGD92024.1 - 0.057 13.3 3.6 0.19 11.6 3.6 1.9 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal Radial_spoke PF04712.12 EGD92025.1 - 0.029 13.3 2.7 0.035 13.1 2.7 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Sugar_tr PF00083.24 EGD92027.1 - 5.2e-86 289.3 18.1 6.2e-86 289.0 18.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGD92027.1 - 2.9e-13 49.5 42.2 7.5e-10 38.3 32.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_4 PF01063.19 EGD92028.2 - 6.4e-17 62.2 0.0 1.8e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 Amino-transferase class IV Cyclin PF08613.11 EGD92029.1 - 9.3e-06 26.1 0.0 9.3e-06 26.1 0.0 2.9 3 1 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 EGD92029.1 - 0.0033 17.2 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-MYND PF01753.18 EGD92031.2 - 9e-08 32.1 9.5 9e-08 32.1 9.5 1.9 2 0 0 2 2 2 1 MYND finger Cation_efflux PF01545.21 EGD92032.1 - 3.1e-30 105.4 10.8 7.3e-30 104.2 10.8 1.6 1 1 0 1 1 1 1 Cation efflux family MARVEL PF01284.23 EGD92032.1 - 8.3e-05 22.6 0.2 0.36 10.8 0.0 2.5 1 1 1 2 2 2 2 Membrane-associating domain EphA2_TM PF14575.6 EGD92032.1 - 0.042 14.7 1.5 2.5 9.0 0.0 3.3 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2946 PF11162.8 EGD92032.1 - 8.5 7.1 13.8 1.3 9.7 7.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2946) Pkinase PF00069.25 EGD92033.1 - 6.2e-07 29.0 0.0 1.9e-05 24.2 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain LysM PF01476.20 EGD92034.2 - 0.0034 17.4 0.0 0.0054 16.8 0.0 1.3 1 0 0 1 1 1 1 LysM domain SH3BGR PF04908.15 EGD92034.2 - 4.9 7.4 4.6 12 6.1 0.5 2.4 1 1 1 2 2 2 0 SH3-binding, glutamic acid-rich protein Ribosomal_S13 PF00416.22 EGD92036.2 - 7.6e-51 171.8 2.5 8.7e-51 171.6 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EGD92036.2 - 0.03 13.1 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.11 EGD92036.2 - 0.066 12.3 0.0 0.077 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Peptidase_S10 PF00450.22 EGD92037.1 - 2e-130 436.0 0.1 2.3e-130 435.8 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EGD92037.1 - 6.1e-06 26.8 0.6 4.5e-05 24.0 0.6 2.3 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide SBDS_C PF09377.10 EGD92038.1 - 7.2e-43 145.3 0.0 1.1e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EGD92038.1 - 1.3e-32 111.7 0.1 2.5e-32 110.8 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Tox-REase-9 PF15650.6 EGD92038.1 - 0.03 14.6 0.1 0.1 12.9 0.1 1.9 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 NST1 PF13945.6 EGD92038.1 - 0.04 14.0 11.2 1.5 8.9 1.3 3.2 3 0 0 3 3 3 0 Salt tolerance down-regulator POX PF07526.11 EGD92038.1 - 0.47 11.0 3.7 2.4 8.7 0.4 2.2 2 0 0 2 2 2 0 Associated with HOX FAM176 PF14851.6 EGD92038.1 - 2.4 7.8 7.1 7.8 6.1 0.9 2.9 3 0 0 3 3 3 0 FAM176 family DUF3679 PF12438.8 EGD92040.1 - 0.0056 16.3 0.1 0.02 14.6 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3679) Peptidase_S29 PF02907.15 EGD92040.1 - 0.073 12.8 0.1 0.52 10.1 0.1 2.1 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Peptidase_S8 PF00082.22 EGD92042.2 - 4.2e-33 114.9 8.7 9e-33 113.8 8.7 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGD92042.2 - 1.3e-14 54.7 0.1 2.2e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pyridoxal_deC PF00282.19 EGD92043.1 - 2e-78 263.7 0.0 2.6e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGD92043.1 - 3e-05 23.1 0.0 4.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EGD92043.1 - 0.034 12.9 0.0 0.051 12.3 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 EGD92043.1 - 0.054 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans_2 PF11951.8 EGD92044.2 - 0.008 15.0 1.2 0.18 10.6 0.7 2.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain HPIP PF15226.6 EGD92044.2 - 0.07 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family adh_short_C2 PF13561.6 EGD92046.1 - 9e-62 208.7 0.2 1e-61 208.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD92046.1 - 2.4e-42 144.6 0.3 2.8e-42 144.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD92046.1 - 2e-14 53.9 0.1 3e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 KR domain LktC PF06261.11 EGD92046.1 - 0.065 13.2 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC YjeF_N PF03853.15 EGD92046.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus DUF2526 PF10735.9 EGD92048.1 - 0.12 12.5 0.1 9 6.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) FAD_binding_3 PF01494.19 EGD92049.1 - 3.7e-22 79.0 0.0 5.1e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGD92049.1 - 1.8e-07 30.7 0.8 0.00098 18.4 0.1 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGD92049.1 - 3.1e-06 27.7 0.3 0.00052 20.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGD92049.1 - 0.00064 19.4 1.5 0.0063 16.1 1.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGD92049.1 - 0.0013 17.9 0.6 0.0024 17.0 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EGD92049.1 - 0.005 15.8 0.1 5 5.8 0.0 3.0 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EGD92049.1 - 0.013 15.7 0.4 0.029 14.6 0.4 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 EGD92049.1 - 0.029 13.4 0.0 0.057 12.5 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase Amino_oxidase PF01593.24 EGD92049.1 - 0.057 12.7 0.0 0.64 9.2 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EGD92049.1 - 0.14 11.4 0.5 8.3 5.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EGD92049.1 - 0.14 12.0 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EGD92049.1 - 0.22 10.5 0.3 0.32 10.0 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A RAD51_interact PF15696.5 EGD92050.1 - 0.088 12.9 1.6 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 RAD51 interacting motif Polysacc_deac_1 PF01522.21 EGD92051.1 - 1.8e-27 95.7 0.0 4.3e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EGD92051.1 - 4.6e-09 36.6 41.3 7.4e-05 23.1 16.3 2.5 2 0 0 2 2 2 2 Chitin recognition protein DUF2334 PF10096.9 EGD92051.1 - 0.026 14.2 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) RGS PF00615.19 EGD92051.1 - 0.081 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain RTP1_C1 PF10363.9 EGD92054.1 - 3e-30 104.7 0.2 4e-29 101.1 0.0 2.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EGD92054.1 - 1.4e-10 40.7 0.0 3.2e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 Lig_chan-Glu_bd PF10613.9 EGD92054.1 - 0.084 13.1 0.1 3.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site Mis14 PF08641.12 EGD92054.1 - 0.095 13.0 0.8 0.26 11.6 0.6 1.9 2 0 0 2 2 2 0 Kinetochore protein Mis14 like DBR1 PF05011.13 EGD92055.1 - 7.6e-43 146.3 0.0 3.3e-42 144.2 0.0 2.0 1 1 1 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EGD92055.1 - 3.9e-06 27.5 1.7 6.6e-06 26.8 1.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rpr2 PF04032.16 EGD92056.1 - 2.2e-12 47.1 1.4 2.2e-12 47.1 1.4 2.2 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.10 EGD92056.1 - 0.0085 16.2 0.6 2.3 8.4 0.1 2.5 2 0 0 2 2 2 2 Zinc ribbon domain zf-ribbon_3 PF13248.6 EGD92056.1 - 0.024 14.0 0.1 0.052 13.0 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-ZPR1 PF03367.13 EGD92057.1 - 3.9e-87 290.0 0.0 9.8e-50 168.5 0.0 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-ISL3 PF14690.6 EGD92057.1 - 0.28 11.9 2.0 18 6.1 0.0 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.7 EGD92057.1 - 0.3 11.1 1.4 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain UPF0547 PF10571.9 EGD92057.1 - 4.4 7.5 8.7 2.2 8.4 1.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Pro_isomerase PF00160.21 EGD92058.1 - 1.7e-34 119.4 0.0 2.7e-34 118.7 0.0 1.4 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.22 EGD92059.2 - 2.2e-09 37.9 0.0 5.4e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.7 EGD92061.1 - 1.3e-29 102.1 0.0 2.3e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EGD92061.1 - 0.0065 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Skp1_POZ PF03931.15 EGD92062.2 - 3.3e-09 36.8 0.0 5.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Nif11 PF07862.11 EGD92062.2 - 0.096 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Nif11 domain Pkinase PF00069.25 EGD92063.1 - 2.7e-07 30.2 0.0 7.5e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGD92063.1 - 8.9e-07 29.1 2.8 5.6e-06 26.5 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGD92063.1 - 0.00014 21.3 0.0 0.00035 20.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGD92063.1 - 0.0084 15.7 0.1 0.029 14.0 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase HSDR_N_2 PF13588.6 EGD92063.1 - 0.014 15.4 0.1 4.5 7.3 0.0 3.2 3 0 0 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) SR-25 PF10500.9 EGD92063.1 - 0.054 13.1 14.7 0.039 13.6 10.3 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein adh_short_C2 PF13561.6 EGD92064.2 - 4.9e-32 111.4 3.1 2.1e-30 106.0 3.1 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD92064.2 - 9.1e-31 106.8 4.0 7.9e-17 61.4 0.1 2.7 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EGD92064.2 - 1.8e-07 31.3 2.3 1.1e-06 28.7 0.1 2.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 EGD92064.2 - 0.0001 21.9 0.1 0.00029 20.4 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGD92064.2 - 0.0032 16.6 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGD92064.2 - 0.0042 16.3 0.0 0.008 15.4 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Q_salvage PF10343.9 EGD92066.2 - 6e-91 304.9 0.3 7.6e-91 304.6 0.3 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family ORC6 PF05460.13 EGD92067.1 - 9.9e-47 159.9 0.3 1.2e-46 159.6 0.3 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Senescence_reg PF04520.13 EGD92067.1 - 0.012 16.5 3.1 0.06 14.2 0.7 2.3 2 0 0 2 2 2 0 Senescence regulator Amidase PF01425.21 EGD92068.1 - 8.2e-89 298.6 0.0 1.1e-88 298.2 0.0 1.2 1 0 0 1 1 1 1 Amidase DNA_pol_delta_4 PF04081.13 EGD92069.2 - 4.5e-12 46.4 4.8 9.8e-12 45.4 4.3 2.0 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Rrp15p PF07890.12 EGD92069.2 - 0.47 10.8 9.9 1 9.7 9.9 1.8 1 1 0 1 1 1 0 Rrp15p CFEM PF05730.11 EGD92071.1 - 4.1e-15 55.6 9.5 5.7e-15 55.2 9.5 1.2 1 0 0 1 1 1 1 CFEM domain Citrate_bind PF16114.5 EGD92072.1 - 5.5e-87 289.9 0.0 7.8e-87 289.3 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EGD92072.1 - 2.1e-07 30.7 0.0 3.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 EGD92072.1 - 0.063 11.4 0.0 0.087 10.9 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Citrate_synt PF00285.21 EGD92073.1 - 1.4e-19 70.4 0.0 1.6e-16 60.4 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 EGD92073.1 - 2.2e-18 66.7 0.1 8.9e-18 64.8 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EGD92073.1 - 7.4e-13 48.6 0.1 1.3e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EGD92073.1 - 1.5e-05 24.8 0.1 0.00015 21.6 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain RNase_P_Rpp14 PF01900.19 EGD92074.1 - 1.3e-38 131.4 0.0 1.6e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.17 EGD92075.1 - 1.3e-77 260.9 0.0 1.6e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 EGD92075.1 - 0.0011 18.9 0.0 0.5 10.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain MeaB PF03308.16 EGD92075.1 - 0.0016 17.5 0.1 0.0039 16.2 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EGD92075.1 - 0.0021 18.1 0.0 0.012 15.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.7 EGD92075.1 - 0.0099 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain KTI12 PF08433.10 EGD92075.1 - 0.02 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Fer4_NifH PF00142.18 EGD92075.1 - 0.021 14.3 0.1 0.053 13.0 0.1 1.7 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 EGD92075.1 - 0.03 14.7 0.0 0.049 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 EGD92075.1 - 0.05 14.0 0.1 0.14 12.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGD92075.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGD92075.1 - 0.061 13.6 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGD92075.1 - 0.077 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EGD92075.1 - 0.081 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 EGD92075.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 EGD92075.1 - 0.11 13.0 0.1 0.29 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGD92075.1 - 0.19 11.9 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EGD92076.1 - 1.7e-12 47.6 2.8 0.13 13.2 0.6 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat HNH_2 PF13391.6 EGD92077.1 - 2.2e-11 43.7 0.0 5.4e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease AMP-binding PF00501.28 EGD92079.2 - 0 1240.0 0.0 8.5e-78 261.8 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.20 EGD92079.2 - 6.7e-271 898.6 0.0 1.7e-51 175.4 0.0 8.9 9 1 0 9 9 9 8 Condensation domain PP-binding PF00550.25 EGD92079.2 - 2.6e-52 175.0 11.3 5.3e-09 36.3 0.1 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGD92079.2 - 1.3e-13 51.7 0.0 0.02 15.9 0.0 5.4 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain DUF5122 PF17164.4 EGD92079.2 - 0.08 13.2 3.1 51 4.3 0.1 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller ASC PF00858.24 EGD92079.2 - 0.1 11.5 0.1 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel TraD_N PF12615.8 EGD92079.2 - 0.2 12.4 1.0 57 4.6 0.4 3.2 2 0 0 2 2 2 0 F sex factor protein N terminal p450 PF00067.22 EGD92080.2 - 2.3e-61 208.0 0.0 3e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1729 PF08354.10 EGD92081.1 - 1.8e-137 458.0 0.0 2.7e-137 457.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EGD92081.1 - 1.1e-66 225.5 0.0 4.1e-66 223.7 0.0 2.0 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 EGD92081.1 - 5.5e-39 133.3 0.0 1.3e-38 132.1 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydrat_N PF13452.6 EGD92081.1 - 4.7e-27 94.7 0.0 4.3e-25 88.4 0.0 2.7 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase SAT PF16073.5 EGD92081.1 - 8.1e-27 94.5 0.3 2e-26 93.2 0.3 1.7 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 EGD92081.1 - 8e-24 83.6 0.0 1.8e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 EGD92081.1 - 1.1e-05 25.5 0.0 3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta 4HBT_2 PF13279.6 EGD92082.1 - 2e-07 31.5 0.0 3.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily RTA1 PF04479.13 EGD92083.1 - 6.9e-54 182.6 7.1 1.1e-53 182.0 7.1 1.3 1 0 0 1 1 1 1 RTA1 like protein ABC_tran PF00005.27 EGD92084.2 - 1.4e-48 164.9 0.0 2.1e-27 96.3 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGD92084.2 - 6.9e-33 114.5 20.3 1.3e-22 80.7 10.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGD92084.2 - 2.6e-12 46.6 6.0 0.00023 20.7 0.2 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGD92084.2 - 1.5e-10 41.4 2.4 0.095 12.5 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGD92084.2 - 6.5e-08 32.2 0.3 0.0094 15.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGD92084.2 - 5.5e-07 29.6 0.2 0.021 14.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGD92084.2 - 1.7e-05 25.3 1.0 0.23 11.8 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain NB-ARC PF00931.22 EGD92084.2 - 1.8e-05 24.1 0.6 0.0014 17.9 0.1 2.8 2 1 0 2 2 2 1 NB-ARC domain AAA_23 PF13476.6 EGD92084.2 - 4.2e-05 24.1 1.0 0.034 14.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGD92084.2 - 4.3e-05 23.8 0.1 0.42 10.9 0.1 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGD92084.2 - 7.6e-05 22.8 0.0 0.6 10.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 EGD92084.2 - 0.00023 21.7 0.1 0.071 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGD92084.2 - 0.00057 19.9 0.3 15 5.6 0.1 4.3 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGD92084.2 - 0.0009 19.6 0.0 0.62 10.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 EGD92084.2 - 0.0013 18.3 0.3 0.52 9.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 EGD92084.2 - 0.0017 18.8 0.2 2.7 8.4 0.1 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EGD92084.2 - 0.002 17.9 2.4 0.81 9.3 0.4 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EGD92084.2 - 0.0023 18.1 0.0 2.3 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGD92084.2 - 0.0044 16.6 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGD92084.2 - 0.0074 16.2 0.5 0.47 10.3 0.0 3.4 4 0 0 4 4 3 1 NACHT domain NTPase_1 PF03266.15 EGD92084.2 - 0.0078 16.1 0.4 1.2 9.0 0.2 2.4 2 0 0 2 2 2 1 NTPase Dynamin_N PF00350.23 EGD92084.2 - 0.0084 16.2 3.5 2.2 8.3 0.1 2.5 2 0 0 2 2 2 2 Dynamin family Rad17 PF03215.15 EGD92084.2 - 0.0085 16.0 2.0 1.6 8.7 0.0 3.3 2 1 0 3 3 3 1 Rad17 P-loop domain AAA_30 PF13604.6 EGD92084.2 - 0.0099 15.6 0.0 4 7.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 EGD92084.2 - 0.016 14.3 0.3 3.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF815 PF05673.13 EGD92084.2 - 0.016 14.4 0.1 0.87 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EGD92084.2 - 0.023 14.4 0.0 0.45 10.2 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGD92084.2 - 0.03 13.6 0.0 8.3 5.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 EGD92084.2 - 0.034 13.7 0.8 0.32 10.6 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EGD92084.2 - 0.04 13.6 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF502 PF04367.13 EGD92084.2 - 0.05 13.5 0.3 20 5.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF502) ATPase_2 PF01637.18 EGD92084.2 - 0.055 13.4 0.2 0.25 11.2 0.0 2.1 3 0 0 3 3 1 0 ATPase domain predominantly from Archaea AIG1 PF04548.16 EGD92084.2 - 0.071 12.4 0.8 2.6 7.3 0.0 2.7 3 0 0 3 3 2 0 AIG1 family Roc PF08477.13 EGD92084.2 - 0.083 13.1 0.2 16 5.7 0.1 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 EGD92084.2 - 0.1 12.4 0.7 0.38 10.4 0.1 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 EGD92084.2 - 0.11 12.8 1.2 22 5.4 0.0 3.7 4 0 0 4 4 3 0 AAA domain ATP-synt_ab PF00006.25 EGD92084.2 - 0.13 11.9 0.2 15 5.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 EGD92084.2 - 0.16 11.7 1.0 5.9 6.6 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Septin PF00735.18 EGD92084.2 - 0.16 11.2 0.1 15 4.8 0.0 2.2 2 0 0 2 2 2 0 Septin TsaE PF02367.17 EGD92084.2 - 0.16 11.9 0.1 24 4.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IZUMO PF15005.6 EGD92084.2 - 0.18 12.3 0.4 0.39 11.2 0.1 1.6 2 0 0 2 2 1 0 Izumo sperm-egg fusion, Ig domain-associated dNK PF01712.19 EGD92084.2 - 0.81 9.5 1.9 18 5.1 0.1 2.8 3 0 0 3 3 3 0 Deoxynucleoside kinase Aminotran_4 PF01063.19 EGD92085.2 - 1.6e-25 90.3 0.0 5e-25 88.7 0.0 1.7 1 1 0 1 1 1 1 Amino-transferase class IV Fas_alpha_ACP PF18325.1 EGD92086.1 - 2.1e-63 213.5 0.0 4.4e-63 212.4 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 EGD92086.1 - 5.8e-38 130.6 0.0 5.8e-38 130.6 0.0 1.8 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 EGD92086.1 - 5.5e-20 72.0 0.0 1.2e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGD92086.1 - 7.7e-12 45.3 0.0 1.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Rib_5-P_isom_A PF06026.14 EGD92087.1 - 9.5e-43 145.8 0.0 1.6e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) ThiF PF00899.21 EGD92088.1 - 2.7e-16 59.7 0.0 1.5e-15 57.3 0.0 2.0 1 1 0 1 1 1 1 ThiF family SPX PF03105.19 EGD92089.1 - 5.7 6.7 11.6 7.9 6.3 11.6 1.2 1 0 0 1 1 1 0 SPX domain Asp PF00026.23 EGD92090.2 - 2.1e-05 24.1 0.0 3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 EGD92090.2 - 0.1 12.0 5.0 0.21 11.0 5.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-C3HC4_3 PF13920.6 EGD92092.1 - 2.1e-09 37.1 12.2 3.5e-09 36.4 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGD92092.1 - 0.12 12.3 13.1 0.23 11.4 13.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Mod_r PF07200.13 EGD92094.2 - 0.027 14.6 1.1 0.039 14.1 1.1 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Ndr PF03096.14 EGD92094.2 - 0.07 11.8 0.4 0.077 11.7 0.4 1.1 1 0 0 1 1 1 0 Ndr family TAF6_C PF07571.13 EGD92094.2 - 0.14 12.5 0.2 10 6.5 0.0 2.5 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain XAP5 PF04921.14 EGD92095.1 - 2.9e-84 282.8 0.0 5.8e-84 281.8 0.0 1.4 1 1 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 EGD92095.1 - 0.0046 17.4 6.0 0.009 16.5 6.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Fip1 PF05182.13 EGD92096.1 - 1.1e-20 72.9 1.9 1.9e-20 72.1 1.9 1.4 1 0 0 1 1 1 1 Fip1 motif WRNPLPNID PF15017.6 EGD92096.1 - 0.71 10.8 7.8 1.8 9.5 7.8 1.8 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Nop14 PF04147.12 EGD92096.1 - 6.8 4.8 7.8 8.1 4.5 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family Cpn10 PF00166.21 EGD92097.1 - 2.7e-27 94.6 0.0 3e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Nucleoporin_FG PF13634.6 EGD92099.1 - 6e-07 30.2 72.2 0.013 16.4 27.0 3.6 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF1664 PF07889.12 EGD92099.1 - 0.0046 17.0 0.9 1.2 9.1 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Lectin_N PF03954.14 EGD92099.1 - 0.13 12.0 0.3 17 5.1 0.0 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain WD40 PF00400.32 EGD92100.2 - 0.046 14.6 0.2 1.2e+02 3.8 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Lactonase PF10282.9 EGD92100.2 - 0.089 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller HAD_2 PF13419.6 EGD92103.2 - 6.2e-14 52.5 0.0 9.4e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGD92103.2 - 1.8e-07 31.7 0.0 2e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGD92103.2 - 0.034 14.2 0.0 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 HAD-hyrolase-like Pkinase PF00069.25 EGD92104.2 - 3.2e-20 72.6 0.0 2.7e-13 49.9 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD92104.2 - 1.1e-07 31.4 0.0 0.00012 21.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase TPR_1 PF00515.28 EGD92105.1 - 5.4e-08 32.3 3.1 0.00022 20.9 0.0 4.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGD92105.1 - 1.4e-05 24.8 3.2 0.03 14.4 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGD92105.1 - 2.3e-05 24.0 0.6 0.00022 20.8 0.1 2.6 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 EGD92105.1 - 0.00024 20.9 0.8 0.13 12.3 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGD92105.1 - 0.00032 20.9 2.0 0.00041 20.6 0.1 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGD92105.1 - 0.014 16.2 1.8 0.21 12.5 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGD92105.1 - 0.049 14.1 0.1 0.42 11.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5113 PF17140.4 EGD92105.1 - 0.13 12.1 0.4 0.24 11.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) TPR_6 PF13174.6 EGD92105.1 - 0.58 10.9 2.4 59 4.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3112 PF11309.8 EGD92106.2 - 6.7e-12 45.3 8.4 2e-09 37.3 0.4 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) adh_short_C2 PF13561.6 EGD92107.1 - 5e-48 163.7 0.5 6.3e-48 163.4 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGD92107.1 - 7.8e-44 149.5 0.3 1e-43 149.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGD92107.1 - 1.5e-10 41.3 0.1 2.2e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGD92107.1 - 0.014 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 EGD92107.1 - 0.022 14.1 0.2 0.033 13.5 0.2 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 EGD92107.1 - 0.17 11.9 0.1 0.35 10.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Metallophos PF00149.28 EGD92108.1 - 1.6e-37 130.0 0.4 2.8e-37 129.2 0.4 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EGD92108.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PI31_Prot_N PF11566.8 EGD92109.1 - 4.2e-37 127.4 0.0 6.3e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EGD92109.1 - 1.6e-18 67.6 13.9 1.6e-18 67.6 13.9 2.8 3 0 0 3 3 3 1 PI31 proteasome regulator DUF2183 PF09949.9 EGD92111.1 - 6.8e-32 109.7 0.0 2.2e-31 108.1 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) HrpB2 PF09487.10 EGD92111.1 - 0.0024 18.3 0.3 0.0024 18.3 0.3 2.0 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB2) CarboxypepD_reg PF13620.6 EGD92111.1 - 0.034 14.4 0.1 0.3 11.4 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain RPAP1_N PF08621.10 EGD92111.1 - 0.066 13.0 2.2 0.13 12.0 2.2 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal Metallophos_2 PF12850.7 EGD92112.1 - 2.9e-06 27.6 0.0 0.015 15.5 0.0 2.1 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGD92112.1 - 5.5e-06 27.0 0.0 9.7e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase LEA_6 PF10714.9 EGD92113.1 - 1.6 8.9 4.6 1.2 9.2 0.6 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Amino_oxidase PF01593.24 EGD92114.2 - 1.4e-26 93.8 0.0 4.3e-26 92.2 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Aldedh PF00171.22 EGD92118.1 - 1.7e-103 346.6 0.0 2e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 EGD92119.1 - 2.7e-65 220.8 4.0 3.4e-65 220.5 4.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Hydrolase PF00702.26 EGD92119.1 - 0.075 13.3 0.4 4.2 7.6 0.1 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Radical_SAM PF04055.21 EGD92120.2 - 1.9e-22 80.4 0.1 1.1e-21 77.9 0.1 2.2 2 1 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.12 EGD92120.2 - 2e-22 79.3 0.0 4.3e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation MFS_1 PF07690.16 EGD92121.1 - 2.1e-45 155.2 43.1 2.1e-45 155.2 43.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.12 EGD92121.1 - 0.0001 21.0 1.2 0.00018 20.2 0.0 1.9 2 0 0 2 2 2 1 Ferroportin1 (FPN1) Sugar_tr PF00083.24 EGD92121.1 - 0.00031 19.7 23.9 0.0021 17.0 23.9 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_C3 PF00548.20 EGD92123.1 - 0.045 13.7 0.0 4.5 7.2 0.0 2.2 2 0 0 2 2 2 0 3C cysteine protease (picornain 3C) HNH_2 PF13391.6 EGD92125.2 - 4.7e-06 26.6 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.25 EGD92127.2 - 1.3e-09 37.8 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain MACPF PF01823.19 EGD92129.2 - 1.1e-16 61.5 2.0 1.6e-16 61.1 2.0 1.2 1 0 0 1 1 1 1 MAC/Perforin domain CBM_19 PF03427.13 EGD92129.2 - 0.31 11.0 3.4 0.92 9.5 3.4 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) FAD_binding_4 PF01565.23 EGD92130.2 - 6.9e-19 68.0 0.0 1.1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.22 EGD92132.2 - 5.3e-46 157.3 0.0 7e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SQHop_cyclase_N PF13249.6 EGD92133.1 - 0.029 13.5 0.0 6.6 5.7 0.0 2.8 3 0 0 3 3 3 0 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EGD92133.1 - 0.029 13.5 0.3 8.9 5.3 0.0 3.3 2 1 1 3 3 3 0 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 EGD92133.1 - 0.048 13.4 0.0 9.6 6.0 0.0 3.0 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat p450 PF00067.22 EGD92134.2 - 1.9e-41 142.3 0.0 2.1e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGD92135.2 - 9.9e-41 139.9 0.0 1.3e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Na_Ca_ex PF01699.24 EGD92137.1 - 1.2e-32 112.9 37.9 1.1e-16 61.2 11.9 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein p450 PF00067.22 EGD92138.2 - 1e-24 87.1 0.0 9.8e-18 64.1 0.0 3.0 1 1 1 2 2 2 2 Cytochrome P450 DUF3176 PF11374.8 EGD92139.1 - 0.024 14.9 2.0 0.061 13.5 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) ADH_zinc_N_2 PF13602.6 EGD92140.1 - 2.2e-16 61.1 0.0 5.1e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGD92140.1 - 6.2e-09 35.9 0.0 6.8e-08 32.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGD92140.1 - 2.5e-08 33.8 0.0 4.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2OG-FeII_Oxy PF03171.20 EGD92141.1 - 8.3e-15 55.1 0.1 1.5e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ketoacyl-synt PF00109.26 EGD92142.1 - 6.4e-74 248.7 0.0 1.1e-73 247.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EGD92142.1 - 3.3e-48 164.5 2.1 2e-46 158.7 0.0 2.8 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EGD92142.1 - 8.2e-36 124.1 0.0 8.2e-36 124.1 0.0 2.7 4 0 0 4 4 4 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGD92142.1 - 1.6e-33 115.2 0.4 1.6e-33 115.2 0.4 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EGD92142.1 - 2.3e-14 53.5 0.1 6.3e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EGD92142.1 - 1.6e-11 44.6 0.1 6.6e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGD92142.1 - 2.6e-08 33.5 0.0 4.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 EGD92142.1 - 0.001 18.5 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain STATa_Ig PF18214.1 EGD92142.1 - 0.16 12.0 0.1 0.56 10.2 0.0 1.9 2 0 0 2 2 2 0 STATa Immunoglobulin-like domain Trp_DMAT PF11991.8 EGD92143.1 - 5.9e-78 262.8 0.0 7.4e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Orexin PF02072.15 EGD92143.1 - 0.0033 17.4 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Prepro-orexin DUF4060 PF13269.6 EGD92143.1 - 0.17 12.0 0.0 15 5.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4060) FAD_binding_3 PF01494.19 EGD92144.1 - 1.4e-10 41.0 1.1 4.3e-09 36.1 1.1 2.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGD92144.1 - 0.024 13.9 0.0 0.67 9.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGD92144.1 - 0.077 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF871 PF05913.11 EGD92144.1 - 0.21 10.7 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) Lactamase_B PF00753.27 EGD92145.1 - 2e-16 60.6 1.2 5e-14 52.8 1.2 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGD92145.1 - 0.00026 20.6 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 EGD92145.1 - 0.011 15.7 0.0 0.052 13.6 0.0 2.2 3 0 0 3 3 3 0 Beta-lactamase associated winged helix domain Fungal_trans PF04082.18 EGD92146.1 - 6.1e-08 32.0 0.1 9.9e-08 31.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD92146.1 - 1.5e-07 31.4 7.1 2.7e-07 30.6 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_6 PF13516.6 EGD92148.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Leucine Rich repeat Tyosinase_C PF18132.1 EGD92149.2 - 8.3e-17 62.0 0.0 1e-16 61.7 0.0 1.2 1 0 0 1 1 1 1 Tyosinase C-terminal domain Ribosomal_S8e PF01201.22 EGD92152.2 - 2.9e-47 160.3 2.0 4.1e-47 159.8 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e RIBIOP_C PF04950.12 EGD92152.2 - 0.23 10.9 6.4 0.54 9.6 6.4 1.7 1 1 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Ribosomal_L21p PF00829.21 EGD92153.1 - 7.9e-09 35.7 0.0 1.4e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein CutA1 PF03091.15 EGD92153.1 - 0.097 12.5 0.3 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein RIB43A PF05914.12 EGD92153.1 - 0.61 8.8 5.2 0.1 11.4 0.7 1.7 2 0 0 2 2 2 0 RIB43A BES1_N PF05687.13 EGD92153.1 - 1.6 9.1 6.5 7.2 7.0 0.5 2.5 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal Pkinase PF00069.25 EGD92154.1 - 5.4e-49 166.9 0.0 8e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGD92154.1 - 5.8e-18 65.1 0.0 9e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGD92154.1 - 0.0003 20.4 0.2 0.00084 19.0 0.1 1.8 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 EGD92154.1 - 0.00051 20.0 0.0 0.31 10.9 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGD92154.1 - 0.011 15.1 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGD92154.1 - 0.033 13.5 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EGD92154.1 - 0.44 9.2 0.0 0.44 9.2 0.0 2.0 3 0 0 3 3 3 0 Fungal protein kinase DUF4648 PF15505.6 EGD92154.1 - 4.8 8.1 9.8 11 7.0 0.0 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF4648) PWI PF01480.17 EGD92155.2 - 6.6e-32 109.6 0.1 9.5e-32 109.1 0.1 1.2 1 0 0 1 1 1 1 PWI domain FAA_hydrolase PF01557.18 EGD92159.1 - 1.7e-53 181.5 0.0 2.1e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3708 PF12501.8 EGD92160.1 - 0.019 14.7 0.3 0.089 12.6 0.0 2.1 2 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter Nup54_57_C PF18570.1 EGD92160.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain HTH_1 PF00126.27 EGD92160.1 - 0.088 12.8 0.6 0.24 11.4 0.2 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family SF-assemblin PF06705.11 EGD92160.1 - 0.1 11.9 5.8 0.031 13.6 2.8 1.5 2 0 0 2 2 2 0 SF-assemblin/beta giardin PHD_like PF12910.7 EGD92160.1 - 0.15 12.1 0.4 6.4 6.8 0.2 2.1 1 1 1 2 2 2 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Baculo_PEP_C PF04513.12 EGD92160.1 - 0.18 11.8 0.9 0.67 10.0 0.5 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 EGD92160.1 - 0.62 10.2 4.3 3.7 7.7 0.2 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF883 PF05957.13 EGD92160.1 - 0.64 10.6 5.8 0.66 10.6 2.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Cortex-I_coil PF09304.10 EGD92160.1 - 0.92 9.8 6.5 3.2 8.0 4.4 2.5 1 1 2 3 3 3 0 Cortexillin I, coiled coil DEAD PF00270.29 EGD92161.1 - 7.5e-45 152.8 0.7 1.4e-44 151.9 0.7 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD92161.1 - 1.2e-31 109.3 0.3 4.1e-31 107.6 0.1 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD92161.1 - 7.5e-07 29.3 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGD92161.1 - 5.6e-05 22.9 0.1 0.00011 22.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGD92161.1 - 0.00068 20.0 1.2 0.0046 17.3 0.7 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGD92161.1 - 0.0038 17.5 0.4 0.019 15.2 0.4 2.2 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 EGD92161.1 - 0.011 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 EGD92161.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Helicase fragilysinNterm PF16376.5 EGD92161.1 - 0.099 12.4 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of fragilysin Flavi_DEAD PF07652.14 EGD92161.1 - 0.12 12.4 0.2 0.71 9.8 0.2 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain Ctr PF04145.15 EGD92163.1 - 9.6e-30 104.2 0.2 1.2e-29 103.8 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family NuA4 PF09340.10 EGD92164.1 - 2.2e-27 94.7 0.2 2.2e-27 94.7 0.2 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 NUDIX PF00293.28 EGD92167.2 - 5.3e-09 36.2 0.2 2.1e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain TRM13 PF05206.14 EGD92167.2 - 0.077 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 PHINT_rpt PF14882.6 EGD92167.2 - 0.11 12.8 0.3 0.28 11.5 0.3 1.6 1 0 0 1 1 1 0 Phage-integrase repeat unit DUF725 PF05267.12 EGD92167.2 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF725) LETM1 PF07766.13 EGD92168.1 - 3.2e-103 344.8 0.1 5.8e-103 343.9 0.1 1.4 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 EGD92168.1 - 0.0063 16.2 0.3 0.55 10.1 0.0 3.4 4 0 0 4 4 4 1 SAP domain DUF2838 PF10998.8 EGD92169.1 - 2.5e-39 133.9 11.0 2.5e-39 133.9 11.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Exonuc_VII_L PF02601.15 EGD92169.1 - 0.062 12.9 0.3 0.092 12.3 0.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ApoLp-III PF07464.11 EGD92169.1 - 0.064 13.3 2.4 0.11 12.5 2.4 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Tropomyosin_1 PF12718.7 EGD92169.1 - 0.068 13.3 2.2 0.13 12.4 2.2 1.3 1 0 0 1 1 1 0 Tropomyosin like OmpH PF03938.14 EGD92169.1 - 2.7 8.3 8.7 0.99 9.7 5.7 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ank_4 PF13637.6 EGD92170.1 - 2.8e-10 40.5 0.0 0.0005 20.6 0.0 3.7 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGD92170.1 - 4.5e-08 33.6 0.0 0.0042 17.7 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGD92170.1 - 4.8e-08 33.1 0.6 0.0051 17.1 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD92170.1 - 0.00029 21.1 0.2 9.5 7.2 0.0 4.3 4 1 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EGD92170.1 - 0.0037 17.7 0.1 4.9 7.8 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat SMC_N PF02463.19 EGD92171.2 - 2.3e-42 144.9 0.0 2.5e-37 128.4 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGD92171.2 - 2.3e-30 105.3 1.1 1.3e-29 102.9 0.0 2.9 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGD92171.2 - 3.8e-06 26.9 1.9 3.8e-06 26.9 1.9 3.3 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system CALCOCO1 PF07888.11 EGD92171.2 - 0.00094 18.2 3.5 0.00094 18.2 3.5 5.2 3 2 1 5 5 5 3 Calcium binding and coiled-coil domain (CALCOCO1) like SbcCD_C PF13558.6 EGD92171.2 - 0.0029 17.8 0.0 0.03 14.5 0.0 2.8 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF1664 PF07889.12 EGD92171.2 - 0.57 10.2 61.7 1.1 9.2 5.2 8.9 5 3 4 10 10 10 0 Protein of unknown function (DUF1664) WH1 PF00568.23 EGD92172.1 - 0.1 12.6 0.1 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 WH1 domain E3_binding PF02817.17 EGD92173.1 - 2e-12 47.2 0.3 1.4e-10 41.3 0.0 2.8 2 1 0 2 2 2 2 e3 binding domain Abhydrolase_2 PF02230.16 EGD92175.1 - 3.6e-26 92.3 0.0 2.4e-16 60.2 0.0 3.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGD92175.1 - 0.00043 21.0 2.3 0.0006 20.5 2.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGD92175.1 - 0.00046 19.7 0.0 0.0021 17.5 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Sulphotransf PF09037.10 EGD92175.1 - 0.031 13.8 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Stf0 sulphotransferase Hydrolase_4 PF12146.8 EGD92175.1 - 0.18 11.0 0.0 1.2 8.3 0.0 2.1 2 1 0 2 2 2 0 Serine aminopeptidase, S33 HNH_2 PF13391.6 EGD92176.1 - 1.2e-14 54.2 0.1 2.1e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease WD40 PF00400.32 EGD92177.1 - 9.6e-24 83.2 13.9 0.00014 22.6 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD92177.1 - 1.1e-13 51.3 6.4 0.0012 19.1 0.3 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGD92177.1 - 1.5e-07 31.5 0.1 0.0078 16.1 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 EGD92177.1 - 0.024 13.6 0.9 3.8 6.3 0.1 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 EGD92177.1 - 0.025 13.5 0.0 0.064 12.2 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M18 PF02127.15 EGD92178.2 - 2e-139 465.1 0.0 2.2e-139 465.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Sugar_tr PF00083.24 EGD92179.2 - 1e-45 156.5 13.5 1.5e-45 156.0 13.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGD92179.2 - 8.9e-34 117.0 30.2 3.7e-22 78.7 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGD92179.2 - 0.0001 20.7 3.3 0.0001 20.7 3.3 2.1 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.8 EGD92179.2 - 0.064 11.9 6.6 0.024 13.3 1.4 2.3 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Flu_PB1 PF00602.17 EGD92179.2 - 0.065 11.3 0.0 0.091 10.9 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 Hydrolase_6 PF13344.6 EGD92180.1 - 1e-28 99.4 0.0 1.7e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGD92180.1 - 1.5e-16 60.2 0.0 3.2e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGD92180.1 - 1e-10 42.3 0.1 1.4e-08 35.3 0.1 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGD92180.1 - 2.4e-06 27.8 0.2 0.082 13.0 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase UPF0253 PF06786.12 EGD92180.1 - 0.049 13.9 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) Acid_phosphat_B PF03767.14 EGD92180.1 - 0.052 13.1 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF1746 PF08508.10 EGD92182.1 - 2.9e-44 150.1 0.6 4e-44 149.6 0.6 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CLP_protease PF00574.23 EGD92183.1 - 2.2e-71 239.5 0.0 2.8e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Clp protease DHDPS PF00701.22 EGD92183.1 - 0.0053 15.5 0.0 0.0089 14.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Rep_fac_C PF08542.11 EGD92184.2 - 5.2e-24 84.5 0.1 2.9e-23 82.1 0.1 2.2 2 1 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 EGD92184.2 - 3e-12 47.1 0.0 9.1e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGD92184.2 - 2.6e-09 37.1 0.0 2.6e-07 30.6 0.0 2.5 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 EGD92184.2 - 2.9e-05 24.3 0.3 0.0001 22.5 0.1 2.0 2 0 0 2 2 2 1 AAA C-terminal domain AAA_11 PF13086.6 EGD92184.2 - 0.0033 17.3 0.0 0.0049 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGD92184.2 - 0.0072 16.1 0.0 0.021 14.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGD92184.2 - 0.0084 16.4 1.2 0.39 11.0 0.1 3.3 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 EGD92184.2 - 0.052 12.9 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGD92184.2 - 0.065 13.6 0.5 1.2 9.5 0.1 2.6 2 1 1 3 3 3 0 AAA ATPase domain AAA_19 PF13245.6 EGD92184.2 - 0.069 13.5 0.1 0.43 10.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EGD92184.2 - 0.071 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 EGD92184.2 - 0.16 12.0 0.1 4.7 7.2 0.2 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) MFS_1 PF07690.16 EGD92185.2 - 1.6e-41 142.4 49.4 1.6e-41 142.4 49.4 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGD92185.2 - 3.9e-12 45.4 14.2 3.9e-12 45.4 14.2 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGD92185.2 - 2.2e-10 40.0 14.2 2.2e-10 40.0 14.2 2.6 2 2 0 2 2 2 2 Sugar (and other) transporter DUF3522 PF12036.8 EGD92185.2 - 0.0019 18.5 2.6 0.0048 17.2 0.3 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3522) Sec20 PF03908.13 EGD92186.2 - 5.9e-16 58.2 2.4 1.6e-15 56.8 2.4 1.7 1 0 0 1 1 1 1 Sec20 CUT PF02376.15 EGD92186.2 - 0.45 10.7 3.3 2.3 8.5 3.3 2.1 1 1 0 1 1 1 0 CUT domain Plasmid_RAQPRD PF09686.10 EGD92186.2 - 9.5 6.5 8.5 0.51 10.6 0.3 2.7 2 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) MRP_L53 PF10780.9 EGD92187.2 - 1.6e-13 50.6 0.1 2.8e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.19 EGD92188.1 - 5.8e-58 195.2 0.1 8e-58 194.8 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.17 EGD92189.2 - 2.2e-42 145.3 0.0 5.3e-42 144.0 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_M28 PF04389.17 EGD92190.1 - 7.3e-44 149.8 0.4 1.6e-43 148.8 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 EGD92190.1 - 2.2e-13 50.0 0.7 5.8e-13 48.7 0.7 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.14 EGD92190.1 - 0.0057 15.7 0.0 0.2 10.6 0.0 2.4 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 EGD92190.1 - 0.0088 15.8 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SNF2_N PF00176.23 EGD92191.1 - 1.3e-51 175.3 0.2 2.1e-51 174.7 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGD92191.1 - 9.7e-20 71.0 0.4 1.6e-18 67.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD92191.1 - 3e-08 33.9 0.0 6.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGD92191.1 - 1.4e-06 27.7 0.1 2.7e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 EGD92191.1 - 2.3e-05 24.2 0.0 4.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TRAM_LAG1_CLN8 PF03798.16 EGD92196.2 - 2.2e-36 125.5 15.3 4e-36 124.6 15.3 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EGD92196.2 - 9.2e-25 86.1 0.1 2.3e-24 84.8 0.1 1.7 1 0 0 1 1 1 1 TRAM1-like protein MIP PF00230.20 EGD92196.2 - 0.078 12.7 0.6 0.12 12.1 0.6 1.3 1 0 0 1 1 1 0 Major intrinsic protein T_cell_tran_alt PF15128.6 EGD92196.2 - 0.78 9.6 3.5 0.59 10.0 0.7 2.1 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Hira PF07569.11 EGD92197.2 - 1.2e-79 267.2 0.0 2.3e-79 266.2 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 EGD92197.2 - 5.4e-22 77.7 22.1 0.00011 22.9 0.0 8.5 8 1 1 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGD92197.2 - 1.6e-10 41.1 0.1 0.18 12.1 0.0 5.6 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EGD92197.2 - 1.7e-10 40.5 0.1 3.9e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EGD92197.2 - 6.2e-05 22.8 5.3 0.75 9.8 0.0 5.3 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EGD92197.2 - 0.0066 14.5 0.0 0.02 12.9 0.0 1.7 1 1 1 2 2 2 1 IKI3 family YchF-GTPase_C PF06071.13 EGD92198.2 - 1.7e-33 114.6 0.1 3.9e-33 113.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGD92198.2 - 3e-17 62.7 0.0 8.1e-17 61.3 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGD92198.2 - 0.00063 19.3 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 EGD92198.2 - 0.01 15.8 0.1 0.041 13.9 0.1 2.0 2 1 0 2 2 2 0 TGS domain AAA_14 PF13173.6 EGD92198.2 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pre-PUA PF17832.1 EGD92199.1 - 1.6e-22 80.0 0.1 2.2e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EGD92199.1 - 9.2e-14 51.2 0.3 1.4e-13 50.6 0.3 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 EGD92199.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) RIC1 PF07064.13 EGD92200.1 - 9.3e-79 264.4 0.0 1.5e-78 263.7 0.0 1.4 1 0 0 1 1 1 1 RIC1 AP-5_subunit_s1 PF15001.6 EGD92200.1 - 0.2 11.7 0.6 0.4 10.7 0.6 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 SGTA_dimer PF16546.5 EGD92201.1 - 6.3e-24 83.5 0.7 1.1e-23 82.7 0.1 1.7 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 EGD92201.1 - 1.1e-13 50.2 5.5 0.00054 19.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGD92201.1 - 1.2e-13 50.2 3.8 3.1e-05 23.6 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGD92201.1 - 1.3e-09 37.6 4.8 2.2e-06 27.2 0.4 3.0 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.6 EGD92201.1 - 1.8e-09 38.1 17.5 1.2e-06 29.1 3.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGD92201.1 - 3.9e-06 26.6 3.3 0.3 11.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGD92201.1 - 1e-05 25.5 0.9 0.022 15.1 0.4 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGD92201.1 - 2.2e-05 24.6 2.2 0.00066 19.9 0.3 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGD92201.1 - 5e-05 23.0 0.3 4.1 7.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGD92201.1 - 5.4e-05 23.3 1.3 0.00082 19.5 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGD92201.1 - 8.5e-05 23.1 5.4 0.088 13.7 0.7 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat XPC-binding PF09280.11 EGD92201.1 - 0.00065 19.4 3.1 0.0021 17.7 3.1 1.8 2 0 0 2 2 2 1 XPC-binding domain STI1 PF17830.1 EGD92201.1 - 0.00075 19.4 11.4 0.0078 16.1 6.1 2.8 3 0 0 3 3 3 1 STI1 domain TPR_19 PF14559.6 EGD92201.1 - 0.0018 18.8 1.5 0.016 15.7 0.5 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGD92201.1 - 0.063 12.5 0.2 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGD92201.1 - 0.067 13.1 4.0 0.1 12.5 0.6 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat GerD PF17898.1 EGD92201.1 - 0.19 11.7 1.4 0.73 9.8 0.5 2.2 2 0 0 2 2 2 0 Spore germination GerD central core domain DUF4264 PF14084.6 EGD92201.1 - 0.22 11.2 0.0 0.48 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) TPR_6 PF13174.6 EGD92201.1 - 0.31 11.8 3.8 9.5 7.1 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Tim44 PF04280.15 EGD92202.1 - 1.8e-37 128.7 0.0 4.3e-37 127.5 0.0 1.7 2 0 0 2 2 2 1 Tim44-like domain Ribosomal_S11 PF00411.19 EGD92203.1 - 1.6e-06 28.5 0.0 3.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S11 VPS9 PF02204.18 EGD92204.2 - 2.5e-18 66.2 0.1 6.9e-18 64.8 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 EGD92204.2 - 4.4e-16 58.7 0.6 2.1e-13 50.2 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGD92204.2 - 3.9e-11 43.4 0.0 0.0025 18.3 0.0 3.7 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGD92204.2 - 2.9e-05 24.1 0.2 0.64 10.8 0.0 5.6 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EGD92204.2 - 5.6e-05 23.6 0.3 0.36 11.5 0.0 4.9 4 1 0 4 4 4 1 Ankyrin repeats (many copies) PX PF00787.24 EGD92204.2 - 6.2e-05 23.0 0.5 0.00018 21.5 0.5 1.8 1 0 0 1 1 1 1 PX domain Ank PF00023.30 EGD92204.2 - 0.0058 17.0 0.4 11 6.6 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Inhibitor_I78 PF11720.8 EGD92206.1 - 2.1e-13 50.1 0.0 2.5e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 EGD92206.1 - 6.4e-05 23.5 0.1 7.8e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 Potato inhibitor I family Nefa_Nip30_N PF10187.9 EGD92207.1 - 5.3e-32 110.3 12.2 5.3e-32 110.3 12.2 1.9 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 EGD92207.1 - 0.0012 18.6 16.1 0.0015 18.2 16.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Golgin_A5 PF09787.9 EGD92207.1 - 0.61 9.5 12.0 1 8.8 12.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 CK_II_beta PF01214.18 EGD92209.1 - 4.7e-78 261.2 0.1 5.9e-78 260.8 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit zf-B_box PF00643.24 EGD92209.1 - 0.44 10.7 1.9 0.66 10.2 0.4 1.9 2 0 0 2 2 2 0 B-box zinc finger E1-E2_ATPase PF00122.20 EGD92210.1 - 3.2e-46 157.1 1.8 3.2e-46 157.1 1.8 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGD92210.1 - 1.1e-22 81.4 0.2 2.4e-22 80.3 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGD92210.1 - 3.7e-09 36.9 0.0 1.5e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EGD92210.1 - 0.0003 20.6 0.2 0.92 9.2 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.6 EGD92210.1 - 0.0026 18.2 0.1 0.0094 16.4 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain HAD PF12710.7 EGD92210.1 - 0.027 14.9 0.0 0.094 13.1 0.0 1.9 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.8 EGD92211.1 - 1.4e-51 175.5 5.6 1.8e-51 175.2 5.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD92211.1 - 3.1e-05 24.0 13.9 7.1e-05 22.9 13.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 EGD92212.1 - 3.4e-07 30.3 0.3 8.5e-07 29.0 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGD92212.1 - 0.0028 18.3 2.5 0.0035 18.0 2.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EGD92212.1 - 0.04 14.0 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 EGD92212.1 - 0.094 12.3 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EGD92212.1 - 0.17 11.8 0.2 0.31 10.9 0.1 1.5 1 1 0 1 1 1 0 Lipase (class 3) JAB PF01398.21 EGD92213.2 - 1.8e-05 24.7 0.1 0.0012 18.8 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HMG_box PF00505.19 EGD92215.1 - 2e-06 28.1 4.2 2e-06 28.1 4.2 2.6 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGD92215.1 - 2.3e-06 28.1 2.9 2.3e-06 28.1 2.9 2.3 2 0 0 2 2 2 1 HMG-box domain Protamine_like PF06382.11 EGD92215.1 - 0.0021 18.2 0.8 0.0021 18.2 0.8 2.2 2 0 0 2 2 2 1 Protamine and protamine like Neugrin PF06413.11 EGD92215.1 - 0.025 14.6 3.2 0.043 13.8 0.1 2.1 2 0 0 2 2 2 0 Neugrin DEAD PF00270.29 EGD92216.1 - 5.2e-49 166.4 0.0 1.6e-48 164.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGD92216.1 - 1.1e-26 93.3 0.0 3.5e-26 91.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGD92216.1 - 0.005 16.9 0.0 0.034 14.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit WLM PF08325.10 EGD92217.1 - 0.001 19.2 0.3 0.0019 18.3 0.3 1.4 1 0 0 1 1 1 1 WLM domain zf-C2H2 PF00096.26 EGD92218.2 - 3e-12 46.3 8.4 8.2e-07 29.2 0.9 7.5 8 0 0 8 8 7 4 Zinc finger, C2H2 type zf-met PF12874.7 EGD92218.2 - 1.7e-11 44.1 3.0 0.00037 20.8 0.3 4.7 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EGD92218.2 - 6.9e-10 38.9 10.2 5.9e-08 32.8 0.8 6.6 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EGD92218.2 - 6.4e-09 35.9 7.1 0.0036 17.6 0.3 4.6 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EGD92218.2 - 7.2e-08 32.6 7.3 0.00022 21.8 0.6 7.6 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGD92218.2 - 4.2e-07 29.8 12.0 0.00057 19.8 0.6 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGD92218.2 - 5e-06 26.2 1.4 0.098 12.4 0.1 3.7 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 EGD92218.2 - 4.3e-05 23.3 1.9 0.038 13.9 0.3 4.0 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf_UBZ PF18439.1 EGD92218.2 - 0.00031 20.3 1.9 4.3 7.0 0.1 3.9 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 EGD92218.2 - 0.096 12.7 11.4 0.87 9.7 0.6 4.2 3 1 1 4 4 4 0 BED zinc finger zf_ZIC PF18366.1 EGD92218.2 - 0.1 12.7 4.8 3.1 8.0 0.0 3.5 3 0 0 3 3 3 0 Zic proteins zinc finger domain BolA PF01722.18 EGD92218.2 - 0.38 11.1 5.1 0.74 10.1 0.1 3.2 3 1 1 4 4 3 0 BolA-like protein zf-C2H2 PF00096.26 EGD92221.1 - 2.4e-06 27.7 12.8 3.9e-05 23.9 3.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGD92221.1 - 5.6e-06 26.5 3.2 5.6e-06 26.5 3.2 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGD92221.1 - 0.0018 19.0 1.9 0.0018 19.0 1.9 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 EGD92221.1 - 0.0019 18.5 0.9 0.0019 18.5 0.9 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGD92221.1 - 0.014 15.4 1.5 0.014 15.4 1.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGD92221.1 - 0.014 15.6 0.9 0.047 14.0 0.9 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF2225 PF09986.9 EGD92221.1 - 0.018 14.8 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) IBR PF01485.21 EGD92221.1 - 0.061 13.6 1.6 0.13 12.6 1.6 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-Di19 PF05605.12 EGD92221.1 - 0.065 13.5 5.6 0.15 12.4 5.6 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Podoplanin PF05808.11 EGD92223.2 - 0.012 15.7 2.7 0.022 14.9 2.7 1.4 1 0 0 1 1 1 0 Podoplanin SKG6 PF08693.10 EGD92223.2 - 2 7.9 4.1 3.9 7.0 4.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PRCC PF10253.9 EGD92223.2 - 2.2 9.0 10.7 10 6.9 6.6 2.5 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting HAT PF02184.16 EGD92224.1 - 1e-24 86.1 81.5 1.9e-16 59.7 2.6 13.2 14 0 0 14 14 14 6 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 EGD92224.1 - 3.6e-19 69.0 0.1 3.4e-05 24.3 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGD92224.1 - 6.7e-19 67.0 25.1 0.00068 20.2 0.4 11.1 6 2 7 13 13 12 6 Tetratricopeptide repeat Suf PF05843.14 EGD92224.1 - 3.3e-12 47.0 38.1 1.6e-05 25.1 1.8 6.2 3 2 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 EGD92224.1 - 5.1e-09 35.9 3.3 0.59 10.6 0.0 6.8 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGD92224.1 - 6.1e-07 29.2 4.2 12 6.4 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGD92224.1 - 3.9e-05 24.0 18.0 0.73 10.6 0.0 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGD92224.1 - 0.00037 20.4 18.0 1.1 9.5 0.0 8.0 11 0 0 11 11 10 2 Tetratricopeptide repeat SUIM_assoc PF16619.5 EGD92224.1 - 0.005 16.9 3.4 0.006 16.6 0.7 2.7 2 1 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 TPR_16 PF13432.6 EGD92224.1 - 0.013 16.1 9.8 4 8.2 0.0 6.5 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGD92224.1 - 0.018 15.2 2.4 4.3 7.6 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EGD92224.1 - 0.32 11.1 32.2 0.075 13.1 2.8 7.3 6 3 3 9 9 9 0 U3 small nucleolar RNA-associated protein 6 ER PF01133.17 EGD92224.1 - 0.7 9.9 3.3 4.8 7.3 0.6 3.7 3 1 1 4 4 4 0 Enhancer of rudimentary TPR_12 PF13424.6 EGD92224.1 - 8 6.8 19.9 8.3 6.8 0.1 6.8 7 2 0 7 7 6 0 Tetratricopeptide repeat Nop PF01798.18 EGD92225.1 - 2.7e-71 239.7 0.0 4e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EGD92225.1 - 1.8e-47 161.2 1.7 3.5e-47 160.3 1.7 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain RRN3 PF05327.11 EGD92225.1 - 1.1 7.7 6.4 1.6 7.2 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AdoHcyase PF05221.17 EGD92226.1 - 4e-97 325.0 0.0 6.6e-74 248.7 0.3 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EGD92226.1 - 2e-54 184.0 3.3 4.4e-54 182.9 3.1 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGD92226.1 - 1e-05 25.0 0.1 1.8e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EGD92226.1 - 7.2e-05 22.4 0.3 0.00014 21.5 0.3 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EGD92226.1 - 0.0012 19.0 0.1 0.0028 17.9 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain DUF3759 PF12585.8 EGD92227.1 - 5.3e-39 132.2 7.9 6.1e-39 132.0 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Band_7 PF01145.25 EGD92229.1 - 6.2e-30 104.5 0.8 6.2e-30 104.5 0.8 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EGD92229.1 - 4e-23 81.2 2.3 4e-23 81.2 2.3 2.1 2 0 0 2 2 2 1 C-terminal region of band_7 Pox_A11 PF05061.13 EGD92229.1 - 0.02 14.2 0.5 0.031 13.6 0.5 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein RecX PF02631.16 EGD92229.1 - 0.042 14.3 1.5 0.1 13.1 0.6 2.1 1 1 1 2 2 2 0 RecX family Band_7_1 PF13421.6 EGD92229.1 - 0.069 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family SQS_PSY PF00494.19 EGD92230.2 - 4.8e-44 150.8 0.0 8.7e-44 150.0 0.0 1.4 1 1 0 1 1 1 1 Squalene/phytoene synthase Soyouz_module PF14313.6 EGD92230.2 - 0.031 14.0 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) CorA PF01544.18 EGD92231.2 - 2e-14 53.6 7.9 2.9e-07 30.1 0.1 3.8 4 0 0 4 4 4 3 CorA-like Mg2+ transporter protein DNApol_Exo PF18136.1 EGD92232.2 - 1.6e-93 312.9 0.3 2.6e-93 312.2 0.3 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EGD92232.2 - 2.6e-57 194.6 0.0 4.5e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EGD92232.2 - 0.02 14.6 0.1 0.55 9.9 0.1 2.4 1 1 0 1 1 1 0 3'-5' exonuclease TFIIS_M PF07500.14 EGD92232.2 - 0.023 15.2 0.9 0.088 13.3 0.9 1.9 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain Mad3_BUB1_I PF08311.12 EGD92232.2 - 0.18 11.8 0.2 0.42 10.6 0.2 1.5 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 zf-C3HC4_2 PF13923.6 EGD92233.1 - 4.2e-09 36.1 7.1 8.6e-09 35.1 3.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGD92233.1 - 5.2e-09 35.8 3.7 1.2e-08 34.7 3.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGD92233.1 - 4.5e-08 33.3 4.6 7.2e-08 32.6 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGD92233.1 - 4.9e-08 32.7 7.9 1.4e-07 31.2 7.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD92233.1 - 6.6e-08 32.4 5.9 2.9e-07 30.4 1.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGD92233.1 - 8.4e-07 28.9 5.5 1.5e-06 28.0 5.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGD92233.1 - 2.4e-06 27.6 2.6 2.4e-06 27.6 2.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGD92233.1 - 0.00056 19.7 8.0 0.0031 17.3 8.0 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 RNHCP PF12647.7 EGD92233.1 - 0.0074 16.2 1.6 1 9.4 0.2 2.5 1 1 0 2 2 2 1 RNHCP domain zf-Nse PF11789.8 EGD92233.1 - 0.053 13.3 1.5 0.13 12.1 1.5 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 EGD92233.1 - 0.12 12.6 3.9 0.55 10.5 4.0 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 EGD92233.1 - 0.17 11.8 0.6 6.6 6.7 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-rbx1 PF12678.7 EGD92233.1 - 0.19 12.0 6.2 0.64 10.3 6.2 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain DUF1644 PF07800.12 EGD92233.1 - 0.28 11.2 6.1 0.92 9.6 2.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-ANAPC11 PF12861.7 EGD92233.1 - 0.5 10.5 3.7 2.7 8.1 3.7 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EGD92233.1 - 0.51 10.2 3.9 0.53 10.2 1.6 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EGD92233.1 - 5.1 7.0 7.8 27 4.7 7.8 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain UPF0052 PF01933.18 EGD92234.1 - 4.6e-58 196.8 0.0 6.4e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 PI3_PI4_kinase PF00454.27 EGD92235.2 - 3.4e-49 167.9 1.8 4.4e-49 167.6 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EGD92235.2 - 2.7e-45 154.2 0.1 9.4e-45 152.4 0.1 2.1 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EGD92235.2 - 7.3e-12 44.9 0.1 2.2e-11 43.4 0.1 1.9 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 EGD92235.2 - 7e-05 22.2 1.8 0.00015 21.1 1.8 1.5 1 0 0 1 1 1 1 FAT domain Nup192 PF11894.8 EGD92236.2 - 0 1259.8 23.8 0 1259.6 23.8 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Dak1 PF02733.17 EGD92238.2 - 4.3e-106 354.3 2.0 5.6e-106 353.9 2.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EGD92238.2 - 5.1e-48 163.3 0.4 2.3e-47 161.1 0.3 2.0 2 0 0 2 2 2 1 DAK2 domain DUF2497 PF10691.9 EGD92238.2 - 0.093 13.2 0.2 0.35 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) LSM PF01423.22 EGD92239.2 - 4.4e-15 55.1 0.2 1.8e-14 53.2 0.2 1.9 1 1 0 1 1 1 1 LSM domain Rep_fac-A_3 PF08661.11 EGD92241.1 - 9.8e-23 80.5 0.0 1.1e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Glyco_hydro_16 PF00722.21 EGD92242.1 - 1.6e-45 154.8 2.4 2.4e-45 154.2 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFAP1 PF06991.11 EGD92243.1 - 2.8e-66 223.5 14.9 2.8e-66 223.5 14.9 3.0 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing TRAPP PF04051.16 EGD92244.1 - 5.6e-39 133.2 0.0 7.7e-39 132.7 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NAD_kinase PF01513.21 EGD92245.1 - 1.3e-74 251.1 0.0 1.7e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Las1 PF04031.13 EGD92250.1 - 1.6e-48 164.7 0.5 2.7e-48 164.0 0.5 1.4 1 0 0 1 1 1 1 Las1-like HAGH_C PF16123.5 EGD92251.1 - 4.3e-21 75.2 1.1 6.5e-21 74.6 1.1 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EGD92251.1 - 1.4e-16 61.1 5.1 1.2e-15 58.1 5.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGD92251.1 - 0.011 15.3 4.3 0.15 11.6 4.1 2.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.20 EGD92251.1 - 0.09 12.3 0.1 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_S24 PF00717.23 EGD92252.1 - 4.7e-09 36.1 0.0 7.8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EGD92252.1 - 0.00016 21.5 0.0 0.0049 16.7 0.0 2.3 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 PBP PF01161.20 EGD92253.2 - 1.5e-05 25.4 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ABC_tran_Xtn PF12848.7 EGD92253.2 - 3.1 7.9 12.4 0.5 10.4 5.1 2.5 2 0 0 2 2 2 0 ABC transporter Ribosomal_L4 PF00573.22 EGD92254.1 - 2.3e-46 157.9 0.0 3.4e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family ECH_2 PF16113.5 EGD92255.1 - 1.7e-130 435.4 0.0 2.2e-130 435.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGD92255.1 - 2.1e-27 96.0 0.0 1.5e-26 93.3 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase RhoGAP PF00620.27 EGD92256.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain CBS PF00571.28 EGD92257.2 - 4.2e-19 68.8 6.7 7.9e-09 35.8 0.4 3.2 3 0 0 3 3 3 3 CBS domain CRAL_TRIO PF00650.20 EGD92258.1 - 1.8e-36 125.3 0.0 2.5e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGD92258.1 - 5.1e-14 52.2 0.0 1.4e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGD92258.1 - 0.0005 20.2 0.0 0.00073 19.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DNA_pol_E_B PF04042.16 EGD92259.2 - 4.3e-35 121.0 0.0 5.8e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 EGD92259.2 - 6.9e-31 108.1 0.9 9.1e-31 107.7 0.9 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Apc13p PF05839.11 EGD92260.1 - 6.4e-21 74.3 1.1 1.2e-17 63.9 0.1 2.2 1 1 1 2 2 2 2 Apc13p protein IF-2B PF01008.17 EGD92261.1 - 6.6e-70 235.5 0.0 8.5e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Kinesin PF00225.23 EGD92262.2 - 6.9e-113 376.9 0.0 1.1e-112 376.2 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGD92262.2 - 6.4e-26 91.1 0.7 1.3e-25 90.1 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding DUF1460 PF07313.12 EGD92262.2 - 0.065 12.6 1.2 0.13 11.6 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) DUF5094 PF17015.5 EGD92262.2 - 0.081 13.0 5.7 0.23 11.5 5.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) YabA PF06156.13 EGD92262.2 - 0.17 12.5 9.5 4.7 7.9 5.3 3.0 2 0 0 2 2 2 0 Initiation control protein YabA FUSC PF04632.12 EGD92262.2 - 0.18 10.3 3.3 0.17 10.4 1.7 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family BPL_N PF09825.9 EGD92262.2 - 0.81 8.7 3.0 2 7.4 3.0 1.7 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF1043 PF06295.12 EGD92262.2 - 1.6 8.7 8.4 4.4 7.3 8.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PUL PF08324.11 EGD92263.2 - 1.1e-56 192.1 1.1 1.7e-56 191.5 1.1 1.3 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 EGD92263.2 - 3.6e-40 137.2 0.0 7e-40 136.3 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 EGD92263.2 - 3.3e-14 52.7 0.0 6.8e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EGD92263.2 - 9.3e-06 25.6 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EGD92263.2 - 0.0029 18.0 0.3 0.013 15.9 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGD92263.2 - 0.0057 16.0 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 EGD92263.2 - 0.026 14.6 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain AhpC-TSA PF00578.21 EGD92263.2 - 0.068 13.1 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 AhpC/TSA family DUF2847 PF11009.8 EGD92263.2 - 0.15 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) EF-hand_9 PF14658.6 EGD92264.1 - 0.0011 19.2 0.0 0.52 10.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Dak2 PF02734.17 EGD92264.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 DAK2 domain UCH PF00443.29 EGD92265.1 - 7.8e-30 104.2 0.0 3.7e-29 102.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGD92265.1 - 5.9e-07 29.4 1.1 1.4e-05 24.9 1.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alb1 PF09135.11 EGD92266.1 - 1.8e-31 109.1 11.9 3.1e-31 108.4 11.9 1.4 1 0 0 1 1 1 1 Alb1 CTX_RstB PF07459.11 EGD92266.1 - 0.12 12.6 0.2 0.3 11.4 0.2 1.6 1 1 0 1 1 1 0 CTX phage RstB protein Vps16_N PF04841.13 EGD92267.1 - 2.8e-98 329.4 0.0 4.3e-98 328.8 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EGD92267.1 - 2.7e-89 299.4 0.4 4e-89 298.8 0.4 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 EGD92267.1 - 2.6e-05 24.4 0.0 0.0021 18.3 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_lid_2 PF17863.1 EGD92268.1 - 0.00045 20.0 0.0 0.00081 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain Epsilon_antitox PF08998.11 EGD92269.2 - 0.2 12.0 0.1 0.34 11.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial epsilon antitoxin Bestrophin PF01062.21 EGD92270.1 - 9.2e-58 195.9 0.0 1.2e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FHA PF00498.26 EGD92271.2 - 2.3e-14 53.5 0.0 4.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EGD92271.2 - 2.2e-10 40.1 4.2 4.3e-10 39.1 4.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGD92271.2 - 7.2e-07 29.4 8.8 1.3e-06 28.6 8.8 1.5 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 EGD92271.2 - 0.0003 21.1 0.0 0.00065 20.0 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 EGD92271.2 - 0.0011 18.9 6.7 0.0021 18.0 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGD92271.2 - 0.01 15.7 8.1 0.019 14.8 8.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGD92271.2 - 0.016 15.1 8.7 0.03 14.2 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EGD92271.2 - 0.017 15.4 5.5 0.039 14.3 5.5 1.7 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 EGD92271.2 - 0.041 13.9 2.9 0.086 12.9 2.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGD92271.2 - 0.12 12.7 8.2 0.34 11.2 8.2 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGD92271.2 - 0.14 12.2 6.8 0.3 11.2 6.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 EGD92271.2 - 0.17 11.8 5.6 0.35 10.8 5.6 1.6 1 0 0 1 1 1 0 PHD-finger TFIIA PF03153.13 EGD92271.2 - 0.35 10.8 23.0 0.044 13.8 13.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ima1_N PF09779.9 EGD92271.2 - 2.2 9.1 12.2 0.28 12.1 7.5 1.9 2 0 0 2 2 2 0 Ima1 N-terminal domain zf-C3HC4_4 PF15227.6 EGD92271.2 - 2.6 8.3 6.8 5.2 7.3 6.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EGD92271.2 - 3.2 7.4 8.1 6.7 6.4 8.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Arm PF00514.23 EGD92272.2 - 4.8e-64 210.6 24.2 3e-11 42.9 0.1 10.3 9 1 1 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGD92272.2 - 7.6e-15 55.0 18.0 4.5e-05 23.8 0.2 7.4 5 3 3 8 8 8 4 HEAT-like repeat Adaptin_N PF01602.20 EGD92272.2 - 2e-14 53.0 6.9 1.5e-08 33.7 0.2 2.6 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.6 EGD92272.2 - 2.1e-14 53.7 10.2 0.00013 22.3 0.0 6.3 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 EGD92272.2 - 1.1e-13 50.1 14.6 0.2 12.0 0.2 8.3 9 0 0 9 9 9 4 HEAT repeat Arm_2 PF04826.13 EGD92272.2 - 1.4e-09 37.8 5.6 8.2e-06 25.5 1.9 2.4 1 1 0 2 2 2 2 Armadillo-like KAP PF05804.12 EGD92272.2 - 2.3e-09 36.0 0.5 6.6e-09 34.5 0.2 1.7 1 1 1 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EGD92272.2 - 4e-08 32.9 1.3 0.00042 19.7 0.7 2.9 1 1 1 2 2 2 2 V-ATPase subunit H DUF5578 PF17741.1 EGD92272.2 - 1.2e-06 28.2 7.2 0.14 11.6 0.1 4.5 1 1 4 5 5 5 2 Family of unknown function (DUF5578) Cnd1 PF12717.7 EGD92272.2 - 0.00079 19.5 6.2 0.018 15.1 0.6 3.9 1 1 3 4 4 4 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 EGD92272.2 - 0.0012 18.9 2.3 21 5.3 0.0 4.8 1 1 7 8 8 8 0 V-ATPase subunit H HEAT_PBS PF03130.16 EGD92272.2 - 0.0024 18.4 7.8 1.1 10.2 0.5 6.0 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat DUF3361 PF11841.8 EGD92272.2 - 0.0039 17.1 9.2 0.95 9.4 0.1 4.2 1 1 4 5 5 5 1 Domain of unknown function (DUF3361) UNC45-central PF11701.8 EGD92272.2 - 0.0074 16.2 1.8 1 9.3 0.1 3.1 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 EGD92272.2 - 0.028 15.0 0.1 0.54 10.9 0.1 2.8 1 1 3 4 4 4 0 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.9 EGD92272.2 - 0.036 14.1 9.2 1.6 8.8 0.2 4.8 3 3 2 5 5 5 0 Spinocerebellar ataxia type 10 protein domain EXOSC1 PF10447.9 EGD92273.1 - 5e-28 97.9 4.6 7.5e-28 97.3 4.6 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EGD92273.1 - 1.8e-10 40.4 0.0 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region PCB_OB PF17092.5 EGD92273.1 - 0.13 13.0 1.2 0.95 10.2 1.0 2.2 1 1 1 2 2 2 0 Penicillin-binding protein OB-like domain GTP_EFTU_D2 PF03144.25 EGD92274.2 - 4.9e-08 33.2 0.0 1.3e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGD92274.2 - 2.1e-07 30.9 0.0 5.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EGD92274.2 - 2.9e-05 23.8 0.0 0.00038 20.2 0.0 2.6 1 1 0 1 1 1 1 Elongation factor G, domain IV DUF4604 PF15377.6 EGD92275.1 - 2.9e-24 86.4 17.2 3.2e-24 86.3 17.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DRY_EERY PF09750.9 EGD92275.1 - 6.8 7.0 8.7 45 4.3 8.7 2.0 1 1 0 1 1 1 0 Alternative splicing regulator Prp19 PF08606.11 EGD92276.1 - 4.2e-33 113.1 1.2 8e-33 112.2 1.2 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EGD92276.1 - 5e-15 55.6 0.0 2.1e-07 31.2 0.0 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGD92276.1 - 1.9e-10 41.1 10.7 2.7e-05 24.8 0.0 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EGD92276.1 - 2.6e-10 40.0 0.1 0.00018 20.7 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 EGD92276.1 - 6e-06 26.3 0.1 0.06 13.2 0.0 3.5 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A V_ATPase_I_N PF18670.1 EGD92276.1 - 0.00051 20.4 0.2 0.0011 19.3 0.2 1.5 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain WD40_like PF17005.5 EGD92276.1 - 0.0018 17.7 0.0 1 8.7 0.0 2.5 1 1 0 2 2 2 2 WD40-like domain Cytochrom_D1 PF02239.16 EGD92276.1 - 0.0027 16.3 0.3 0.2 10.1 0.1 2.2 1 1 0 2 2 2 1 Cytochrome D1 heme domain Rtf2 PF04641.12 EGD92276.1 - 0.0073 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger HPS3_N PF14761.6 EGD92276.1 - 0.0077 15.8 0.0 3 7.3 0.0 3.0 1 1 2 3 3 3 1 Hermansky-Pudlak syndrome 3 Ge1_WD40 PF16529.5 EGD92276.1 - 0.023 13.7 0.1 0.062 12.2 0.1 1.7 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-Nse PF11789.8 EGD92276.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Frtz PF11768.8 EGD92276.1 - 0.15 10.3 0.0 0.25 9.6 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 EGD92276.1 - 0.17 10.9 0.1 0.3 10.1 0.1 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain zf-RING_5 PF14634.6 EGD92277.1 - 0.00038 20.3 1.7 0.00076 19.4 1.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGD92277.1 - 0.013 15.8 0.8 0.039 14.3 0.9 1.8 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 EGD92277.1 - 0.014 15.2 1.1 0.23 11.4 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGD92277.1 - 0.033 14.2 0.5 0.07 13.2 0.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EGD92277.1 - 0.053 13.4 0.4 2 8.3 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.21 EGD92277.1 - 0.054 13.6 2.9 0.12 12.5 2.9 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_2 PF13923.6 EGD92277.1 - 0.093 12.6 1.2 0.25 11.2 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UBP PF02148.19 EGD92277.1 - 0.22 11.9 2.5 0.69 10.3 2.5 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein GET2 PF08690.10 EGD92277.1 - 0.22 11.2 0.7 0.38 10.4 0.7 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 zf-C3HC4 PF00097.25 EGD92277.1 - 0.34 10.8 3.5 3.2 7.7 4.3 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) L51_S25_CI-B8 PF05047.16 EGD92278.1 - 4.7e-16 58.4 0.3 7.1e-16 57.9 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.8 EGD92279.1 - 6.5e-28 97.2 1.0 1.5e-27 96.1 1.0 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EGD92279.1 - 6.9e-17 61.0 0.0 1.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGD92279.1 - 2.1e-05 24.6 0.0 3.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif RL10P_insert PF17777.1 EGD92280.1 - 4.3e-22 77.9 0.0 9.1e-22 76.8 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EGD92280.1 - 9.3e-19 67.4 0.0 2.2e-18 66.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L10 TIM PF00121.18 EGD92281.2 - 1.9e-89 299.2 0.5 2.3e-89 299.0 0.5 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MDM10 PF12519.8 EGD92282.1 - 1.1e-144 482.8 3.5 3.4e-126 421.8 1.9 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 YjeF_N PF03853.15 EGD92283.2 - 9.3e-34 116.8 0.1 1.4e-33 116.2 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EGD92283.2 - 1.1e-06 29.4 0.5 1.1e-06 29.4 0.5 2.7 3 0 0 3 3 3 1 FDF domain OCD_Mu_crystall PF02423.15 EGD92283.2 - 0.094 11.6 0.2 1 8.2 0.0 2.1 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Pkinase PF00069.25 EGD92284.1 - 2.3e-17 63.3 0.2 3.7e-14 52.7 0.1 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD92284.1 - 6e-10 38.8 0.0 3.1e-07 30.0 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 EGD92284.1 - 5.1e-06 26.2 0.1 9e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pro_isomerase PF00160.21 EGD92285.2 - 5.8e-41 140.4 0.0 1e-40 139.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 EGD92285.2 - 0.00021 21.4 0.0 0.00058 19.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 EGD92285.2 - 0.00049 20.2 0.0 0.0022 18.1 0.0 2.0 1 1 1 2 2 2 1 U-box domain Rtf2 PF04641.12 EGD92285.2 - 0.0013 18.1 0.7 0.0074 15.7 0.7 2.1 1 1 0 1 1 1 1 Rtf2 RING-finger PIF1 PF05970.14 EGD92287.2 - 2.7e-64 217.6 0.1 3.9e-64 217.1 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EGD92287.2 - 6.8e-25 87.9 0.0 1.3e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGD92287.2 - 2.8e-11 44.0 0.0 4.9e-10 39.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGD92287.2 - 5.9e-09 36.3 0.0 1.6e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGD92287.2 - 4.9e-05 22.9 0.2 0.00014 21.4 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 EGD92287.2 - 0.00016 22.1 0.3 0.0005 20.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 EGD92287.2 - 0.00023 20.9 0.1 0.00075 19.3 0.1 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EGD92287.2 - 0.00026 19.1 0.0 0.0011 17.0 0.0 1.8 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 EGD92287.2 - 0.00039 20.2 0.1 0.13 11.9 0.0 2.9 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 EGD92287.2 - 0.0056 16.7 0.1 0.029 14.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGD92287.2 - 0.006 15.8 0.3 0.011 14.9 0.3 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.9 EGD92287.2 - 0.0072 15.6 0.1 0.028 13.7 0.1 2.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EGD92287.2 - 0.012 16.0 0.0 0.041 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EGD92287.2 - 0.016 15.2 0.1 0.074 13.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 EGD92287.2 - 0.021 14.3 0.0 0.06 12.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 EGD92287.2 - 0.039 13.9 1.4 0.27 11.1 1.4 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF5605 PF18310.1 EGD92287.2 - 0.042 13.7 0.0 0.16 11.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) RsgA_GTPase PF03193.16 EGD92287.2 - 0.051 13.5 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EGD92287.2 - 0.052 14.1 0.1 1.3 9.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain SH3_13 PF18335.1 EGD92287.2 - 0.059 13.2 0.0 0.23 11.3 0.0 2.0 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain T2SSE PF00437.20 EGD92287.2 - 0.063 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 EGD92287.2 - 0.065 12.1 0.0 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 EGD92287.2 - 0.091 13.2 0.0 0.31 11.4 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 EGD92287.2 - 0.12 12.8 1.4 0.19 12.1 0.1 2.0 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 EGD92287.2 - 0.16 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EGD92287.2 - 0.35 11.4 2.0 0.62 10.6 0.1 2.3 2 1 0 2 2 1 0 ABC transporter AAA_11 PF13086.6 EGD92287.2 - 0.61 9.8 0.0 0.61 9.8 0.0 2.9 2 1 0 2 2 1 0 AAA domain Dynamin_N PF00350.23 EGD92289.2 - 3.6e-18 66.2 1.1 3e-17 63.2 0.1 2.8 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EGD92289.2 - 2e-10 40.7 0.0 1.1e-08 35.1 0.0 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGD92289.2 - 1.2e-07 31.5 0.0 7.5e-05 22.4 0.1 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF2205 PF10224.9 EGD92289.2 - 0.026 14.5 0.1 0.094 12.7 0.1 1.9 1 0 0 1 1 1 0 Short coiled-coil protein FeoB_N PF02421.18 EGD92289.2 - 0.094 12.2 0.2 40 3.7 0.0 3.7 4 0 0 4 4 4 0 Ferrous iron transport protein B AAA_18 PF13238.6 EGD92289.2 - 0.098 13.2 0.1 0.59 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGD92289.2 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 EGD92289.2 - 0.11 12.7 0.1 3 8.1 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGD92289.2 - 0.16 11.8 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Snf7 PF03357.21 EGD92290.1 - 5.8e-35 120.4 17.5 4.4e-34 117.6 15.8 2.0 2 0 0 2 2 2 1 Snf7 DUF3958 PF13125.6 EGD92290.1 - 6.9 6.9 13.1 0.19 11.9 4.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) Remorin_C PF03763.13 EGD92290.1 - 8.1 6.4 12.7 0.49 10.3 7.2 1.9 2 1 0 2 2 2 0 Remorin, C-terminal region YceG PF02618.16 EGD92291.1 - 0.066 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 YceG-like family PP2C PF00481.21 EGD92292.2 - 2e-49 168.6 1.5 1.3e-36 126.5 0.0 3.5 2 1 1 3 3 3 2 Protein phosphatase 2C AAA_33 PF13671.6 EGD92292.2 - 0.025 14.7 0.1 0.092 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mhr1 PF12829.7 EGD92294.1 - 1.3e-27 95.6 0.2 3e-27 94.5 0.2 1.6 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination RR_TM4-6 PF06459.12 EGD92294.1 - 4.8 6.9 11.5 7.9 6.2 11.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Atg14 PF10186.9 EGD92295.1 - 4.8e-16 58.7 0.0 8.6e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 EGD92295.1 - 7.1e-07 28.5 0.9 0.016 14.1 0.0 3.2 3 0 0 3 3 3 3 Vacuolar protein sorting 38 FUSC PF04632.12 EGD92295.1 - 2.5 6.5 6.9 3.7 6.0 6.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family F-box-like PF12937.7 EGD92299.1 - 5.9e-06 26.1 0.8 1.6e-05 24.7 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGD92299.1 - 0.055 13.4 0.3 0.13 12.2 0.3 1.6 1 0 0 1 1 1 0 F-box domain PalH PF08733.10 EGD92300.1 - 6.6e-114 380.3 0.0 8.5e-114 380.0 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 PLAC8 PF04749.17 EGD92301.1 - 1.4e-21 77.3 16.4 2.1e-21 76.8 16.4 1.3 1 0 0 1 1 1 1 PLAC8 family TFIIA PF03153.13 EGD92301.1 - 8 6.3 33.7 12 5.7 33.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ADH_zinc_N PF00107.26 EGD92304.2 - 1.9e-14 53.8 0.0 3.3e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGD92304.2 - 0.028 14.3 0.0 0.064 13.1 0.0 1.6 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EGD92304.2 - 0.14 11.6 0.2 0.22 10.9 0.2 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Metallophos PF00149.28 EGD92306.1 - 7.7e-06 26.5 0.0 1.6e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EGD92306.1 - 0.0012 19.0 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Transket_pyr PF02779.24 EGD92307.1 - 1.5e-47 161.5 0.0 2.9e-47 160.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGD92307.1 - 3.2e-35 120.7 0.1 8.6e-35 119.3 0.1 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Glyco_hydro_43 PF04616.14 EGD92308.2 - 1.1e-42 146.4 2.3 1.2e-42 146.2 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 zf-C2H2 PF00096.26 EGD92309.1 - 0.0035 17.7 1.2 0.0073 16.7 1.2 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 EGD92309.1 - 0.0062 16.9 0.3 0.011 16.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGD92309.1 - 0.015 15.5 2.3 0.025 14.8 2.3 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EGD92309.1 - 0.089 13.7 0.5 0.22 12.5 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf_PR_Knuckle PF18445.1 EGD92309.1 - 0.16 11.8 0.2 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 PR zinc knuckle motif DUF1691 PF07950.11 EGD92310.1 - 9e-41 138.9 5.3 2.5e-32 111.8 4.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) TRM PF02005.16 EGD92311.1 - 7.3e-109 364.4 0.0 6.7e-94 315.1 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_25 PF13649.6 EGD92311.1 - 0.01 16.5 0.0 0.026 15.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGD92311.1 - 0.025 14.4 0.0 0.078 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.16 EGD92311.1 - 0.046 13.5 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DUF2067 PF09840.9 EGD92311.1 - 0.084 12.4 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) MTS PF05175.14 EGD92311.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain DUF1729 PF08354.10 EGD92313.1 - 6.2e-162 538.4 0.0 9.7e-162 537.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EGD92313.1 - 4.8e-94 315.4 0.1 7.7e-91 304.9 0.0 3.7 5 0 0 5 5 5 2 Acyl transferase domain FAS_meander PF17951.1 EGD92313.1 - 2e-53 180.1 0.0 4.7e-53 178.9 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 EGD92313.1 - 2.4e-38 130.5 0.1 9.7e-38 128.5 0.0 2.0 2 0 0 2 2 2 1 MaoC like domain SAT PF16073.5 EGD92313.1 - 4.9e-38 131.2 0.1 2e-37 129.2 0.0 2.0 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 EGD92313.1 - 1.4e-37 128.6 0.0 1.2e-36 125.5 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 EGD92313.1 - 1.3e-21 77.1 0.0 3.8e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MCRS_N PF13325.6 EGD92313.1 - 0.076 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Gamma-thionin PF00304.20 EGD92314.1 - 0.0034 17.6 7.3 0.0045 17.2 7.3 1.3 1 0 0 1 1 1 1 Gamma-thionin family SLR1-BP PF07333.12 EGD92314.1 - 0.0075 16.7 4.4 0.0088 16.5 4.4 1.2 1 0 0 1 1 1 1 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Myticin-prepro PF10690.9 EGD92314.1 - 0.084 13.1 5.9 0.097 12.9 5.9 1.0 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel His_Phos_2 PF00328.22 EGD92315.1 - 1e-106 357.5 0.0 1.3e-106 357.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EGD92315.1 - 9.6e-38 128.2 0.0 2e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EGD92315.1 - 0.00011 21.8 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain FeoB_associated PF12669.7 EGD92317.1 - 0.13 12.6 0.8 0.22 11.9 0.8 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF383 PF04063.14 EGD92318.1 - 8.6e-69 231.0 0.0 7.9e-68 227.9 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EGD92318.1 - 2e-21 75.6 1.1 2e-21 75.6 1.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF384) Peptidase_C50 PF03568.17 EGD92318.1 - 0.00047 19.4 0.0 0.00085 18.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family C50 SPO22 PF08631.10 EGD92318.1 - 0.088 12.3 0.5 0.17 11.4 0.1 1.6 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like PAP_assoc PF03828.19 EGD92319.1 - 6.1e-08 32.8 0.0 1.6e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGD92319.1 - 0.09 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain TFIIF_alpha PF05793.12 EGD92320.2 - 6.3e-09 35.0 11.6 6.3e-09 35.0 11.6 2.6 1 1 1 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MbeB_N PF04837.12 EGD92320.2 - 2.1 8.7 4.9 0.45 10.9 0.8 2.0 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Herpes_LMP2 PF07415.11 EGD92320.2 - 3.4 6.3 3.5 5.1 5.8 3.5 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DNA_pol_phi PF04931.13 EGD92320.2 - 8.5 4.3 15.9 13 3.7 15.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi IBR PF01485.21 EGD92321.2 - 1.7e-12 47.4 35.5 5.1e-07 29.8 8.8 3.2 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain XPG_I_2 PF12813.7 EGD92322.1 - 1.4e-75 254.0 0.0 2e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc_N PF02739.16 EGD92322.1 - 0.11 12.4 0.1 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain Inositol_P PF00459.25 EGD92323.1 - 5.9e-64 216.2 0.0 2.9e-62 210.7 0.0 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family Connexin40_C PF16791.5 EGD92323.1 - 0.014 16.7 0.2 0.023 16.0 0.2 1.3 1 0 0 1 1 1 0 Connexin 40 C-terminal domain DAGK_cat PF00781.24 EGD92324.1 - 1.3e-12 47.4 0.0 2.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF676 PF05057.14 EGD92325.1 - 6.4e-38 130.4 0.0 6.6e-36 123.9 0.0 3.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EGD92325.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 EGD92325.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Fcf1 PF04900.12 EGD92326.2 - 1.2e-36 125.1 1.2 1.4e-36 124.8 0.3 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 EGD92326.2 - 2.5e-13 50.3 0.4 1.1e-12 48.3 0.1 1.9 2 0 0 2 2 2 1 PIN like domain Ras PF00071.22 EGD92328.1 - 8.5e-65 217.3 0.1 1e-64 217.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGD92328.1 - 3.3e-34 117.7 0.0 4.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGD92328.1 - 1.7e-13 50.4 0.1 2.1e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGD92328.1 - 8.4e-06 25.5 0.1 1.9e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGD92328.1 - 1.7e-05 24.3 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGD92328.1 - 0.00063 19.7 0.1 0.62 10.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGD92328.1 - 0.0016 18.5 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGD92328.1 - 0.0049 16.4 0.0 0.026 14.1 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 EGD92328.1 - 0.0066 15.9 0.1 0.0081 15.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EGD92328.1 - 0.15 12.3 0.1 0.46 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain NCA2 PF08637.10 EGD92329.1 - 1.3e-79 267.4 0.1 2.9e-79 266.3 0.0 1.6 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Dicty_REP PF05086.12 EGD92329.1 - 0.74 7.7 1.4 1 7.2 1.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FA_hydroxylase PF04116.13 EGD92330.2 - 1e-25 90.6 17.1 1e-25 90.6 17.1 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily AAA PF00004.29 EGD92331.1 - 3.2e-58 195.8 0.0 9.2e-41 139.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD92331.1 - 4.3e-12 45.6 0.7 3e-06 26.9 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGD92331.1 - 5.1e-08 33.5 2.3 0.076 13.4 0.7 4.3 2 2 0 3 3 3 2 AAA ATPase domain Bac_DnaA PF00308.18 EGD92331.1 - 6.2e-06 26.2 0.0 0.0044 16.9 0.0 3.0 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.6 EGD92331.1 - 1.4e-05 25.4 0.5 0.34 11.2 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.14 EGD92331.1 - 1.6e-05 25.0 0.7 0.0064 16.5 0.1 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGD92331.1 - 2.5e-05 24.1 0.0 0.014 15.2 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGD92331.1 - 9.8e-05 22.7 0.0 0.16 12.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 EGD92331.1 - 0.00013 21.6 0.1 0.32 10.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region TIP49 PF06068.13 EGD92331.1 - 0.00015 21.1 0.5 0.0023 17.2 0.1 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 EGD92331.1 - 0.00022 21.4 0.0 0.00061 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 EGD92331.1 - 0.00034 20.6 0.0 0.002 18.1 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 EGD92331.1 - 0.00035 20.8 0.0 0.86 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EGD92331.1 - 0.00046 20.2 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGD92331.1 - 0.00084 19.0 0.4 6.2 6.4 0.1 3.9 3 1 1 4 4 4 1 AAA domain IstB_IS21 PF01695.17 EGD92331.1 - 0.0011 18.8 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein CDC48_N PF02359.18 EGD92331.1 - 0.0012 19.0 0.0 0.066 13.4 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain Mg_chelatase PF01078.21 EGD92331.1 - 0.0021 17.5 2.0 0.0092 15.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EGD92331.1 - 0.0026 16.9 0.0 2.8 7.0 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF815) Vps4_C PF09336.10 EGD92331.1 - 0.0066 16.4 0.1 2.4 8.2 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MCM PF00493.23 EGD92331.1 - 0.015 14.4 0.0 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_30 PF13604.6 EGD92331.1 - 0.016 14.9 0.3 3.2 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 EGD92331.1 - 0.017 15.0 0.6 5.7 6.8 0.1 2.8 3 0 0 3 3 2 0 NACHT domain AAA_24 PF13479.6 EGD92331.1 - 0.018 14.8 0.1 5.4 6.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGD92331.1 - 0.023 14.6 0.5 5.9 6.7 0.1 3.1 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EGD92331.1 - 0.11 12.2 0.2 0.94 9.3 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 EGD92331.1 - 0.16 11.7 0.1 7.1 6.3 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EGD92331.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HNH_2 PF13391.6 EGD92332.1 - 1.3e-14 54.1 0.2 4.4e-14 52.4 0.0 2.0 1 1 1 2 2 2 1 HNH endonuclease RRM_1 PF00076.22 EGD92333.1 - 2.9e-14 52.6 0.0 4.2e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGD92333.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGD92333.1 - 0.028 14.3 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif NADH-u_ox-rdase PF10785.9 EGD92336.1 - 7e-27 93.9 0.4 1.8e-26 92.6 0.2 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 EGD92336.1 - 9.5e-27 92.8 0.1 1.4e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.12 EGD92337.2 - 2.4e-31 107.5 0.2 5e-31 106.5 0.2 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 RCC1 PF00415.18 EGD92338.1 - 3.3e-61 203.7 13.3 2.5e-10 40.8 0.2 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGD92338.1 - 1.5e-41 139.3 35.1 2.5e-08 33.5 0.9 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RibD_C PF01872.17 EGD92339.1 - 3.7e-28 98.7 0.0 7.1e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 RibD C-terminal domain Nic96 PF04097.14 EGD92340.2 - 9.3e-222 737.9 0.0 1.1e-221 737.6 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Peptidase_S10 PF00450.22 EGD92342.1 - 5.1e-88 296.3 0.0 8.1e-88 295.6 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Na_Ca_ex PF01699.24 EGD92343.2 - 1.6e-21 76.9 38.0 7.6e-16 58.4 13.7 3.6 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 EGD92343.2 - 6.2e-15 55.7 10.9 6.2e-15 55.7 10.9 4.6 5 0 0 5 5 5 1 Inner membrane component domain AAA PF00004.29 EGD92344.1 - 1.6e-43 148.3 0.0 2.6e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGD92344.1 - 4.2e-14 52.1 0.0 1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGD92344.1 - 9.5e-08 32.3 0.0 1.8e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGD92344.1 - 1.5e-07 31.5 0.0 3.7e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGD92344.1 - 1.8e-06 28.4 0.0 0.00011 22.6 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 EGD92344.1 - 1e-05 25.4 2.1 2.8e-05 24.0 2.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EGD92344.1 - 2.6e-05 24.5 0.2 0.0061 16.8 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGD92344.1 - 5.7e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGD92344.1 - 0.00088 19.8 0.0 0.019 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGD92344.1 - 0.00099 18.4 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGD92344.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGD92344.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EGD92344.1 - 0.0035 17.2 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EGD92344.1 - 0.0077 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 EGD92344.1 - 0.0078 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGD92344.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGD92344.1 - 0.011 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGD92344.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EGD92344.1 - 0.022 14.5 0.0 0.097 12.4 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EGD92344.1 - 0.024 14.1 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EGD92344.1 - 0.035 13.6 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 EGD92344.1 - 0.035 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase HR1 PF02185.16 EGD92344.1 - 0.036 14.2 0.7 0.092 12.9 0.7 1.7 1 0 0 1 1 1 0 Hr1 repeat AAA_14 PF13173.6 EGD92344.1 - 0.037 14.1 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGD92344.1 - 0.039 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGD92344.1 - 0.055 13.1 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EGD92344.1 - 0.063 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 EGD92344.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FGGY_C PF02782.16 EGD92346.2 - 1.4e-50 171.8 0.2 2.3e-50 171.1 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGD92346.2 - 6.9e-07 29.1 0.0 8.6e-06 25.5 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Cas_NE0113 PF09623.10 EGD92348.1 - 0.22 11.2 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) F-box-like_2 PF13013.6 EGD92349.1 - 0.0032 17.4 0.2 0.0076 16.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.33 EGD92349.1 - 0.0035 17.2 2.5 0.0069 16.2 2.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGD92349.1 - 0.13 12.2 2.5 0.34 10.8 2.5 1.8 1 0 0 1 1 1 0 F-box-like RNA_pol_3_Rpc31 PF11705.8 EGD92349.1 - 0.35 11.1 15.6 4.9 7.3 13.8 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 EGD92349.1 - 0.84 9.2 8.4 1.6 8.3 8.4 1.4 1 0 0 1 1 1 0 PPP4R2 TFB6 PF17110.5 EGD92349.1 - 1.2 8.9 4.7 1.9 8.2 4.7 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH F-box_4 PF15966.5 EGD92349.1 - 1.3 9.0 3.7 0.65 9.9 1.2 1.8 2 0 0 2 2 2 0 F-box Y_phosphatase PF00102.27 EGD92350.2 - 4.3e-65 219.6 0.0 6.3e-65 219.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 EGD92350.2 - 3e-10 40.6 0.0 1.4e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 EGD92350.2 - 0.015 15.1 0.6 0.036 13.9 0.6 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CCAP PF11105.8 EGD92350.2 - 0.11 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a COX16 PF14138.6 EGD92352.1 - 2.2e-31 108.2 0.1 2.8e-31 107.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Pkinase PF00069.25 EGD92353.2 - 2.4e-16 59.9 0.0 1.9e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGD92353.2 - 0.0036 16.6 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PSD2 PF07624.11 EGD92354.2 - 0.031 14.1 0.1 0.057 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) tRNA-synt_1g PF09334.11 EGD92357.1 - 1.2e-140 468.8 0.0 1.5e-140 468.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGD92357.1 - 0.0005 18.5 0.9 0.014 13.7 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGD92357.1 - 0.0048 16.9 0.1 0.0096 15.9 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA COesterase PF00135.28 EGD92361.2 - 1.3e-11 44.0 0.0 1.6e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family TrkH PF02386.16 EGD92362.1 - 9.7e-145 482.8 2.3 2e-142 475.2 1.7 2.1 2 0 0 2 2 2 2 Cation transport protein PH PF00169.29 EGD92364.1 - 2.7e-05 24.6 0.3 6.6e-05 23.4 0.3 1.6 1 0 0 1 1 1 1 PH domain Big_3 PF07523.12 EGD92364.1 - 0.11 12.8 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) F-box-like PF12937.7 EGD92366.1 - 6.3e-08 32.4 0.0 1.4e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EGD92366.1 - 0.0018 18.6 2.2 40 4.8 0.1 4.9 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) F-box PF00646.33 EGD92366.1 - 0.068 13.1 0.2 4.3 7.3 0.0 3.2 3 0 0 3 3 3 0 F-box domain TPR_2 PF07719.17 EGD92369.1 - 3.2e-08 33.1 0.0 0.58 10.4 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGD92369.1 - 9.1e-06 25.3 0.0 0.23 11.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGD92369.1 - 0.00033 20.9 0.0 0.0058 16.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat UBA PF00627.31 EGD92369.1 - 0.00049 19.9 0.0 0.0014 18.5 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.31 EGD92369.1 - 0.056 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 DnaJ domain Ank_5 PF13857.6 EGD92370.1 - 1.8e-15 56.8 1.5 2.7e-07 30.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGD92370.1 - 2.4e-13 50.5 0.2 9.8e-13 48.5 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD92370.1 - 3e-10 40.4 0.0 9.8e-06 26.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGD92370.1 - 8.7e-07 29.1 0.3 0.2 12.2 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGD92370.1 - 7.8e-06 25.9 0.2 1.1 10.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat bZIP_1 PF00170.21 EGD92370.1 - 0.18 11.9 8.5 0.38 10.9 8.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor AMP-binding PF00501.28 EGD92371.2 - 5.8e-72 242.6 0.0 8.1e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGD92371.2 - 2e-32 112.5 0.0 2.7e-29 102.1 0.0 2.1 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EGD92371.2 - 7.2e-13 48.7 0.0 1.9e-10 40.9 0.0 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site DegT_DnrJ_EryC1 PF01041.17 EGD92372.2 - 2.6e-49 168.5 0.0 4.2e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GFO_IDH_MocA PF01408.22 EGD92372.2 - 4e-19 69.6 0.0 8.4e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGD92372.2 - 0.00023 21.1 0.0 0.00058 19.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Aminotran_5 PF00266.19 EGD92372.2 - 0.00052 19.1 0.0 0.00086 18.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V CoA_binding PF02629.19 EGD92372.2 - 0.00089 19.9 0.0 0.0033 18.1 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Beta_elim_lyase PF01212.21 EGD92372.2 - 0.0011 18.4 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EGD92372.2 - 0.0029 16.2 0.0 0.0047 15.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Semialdhyde_dh PF01118.24 EGD92372.2 - 0.0062 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 5_nucleotid_C PF02872.18 EGD92373.1 - 7e-34 117.3 0.0 1.4e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGD92373.1 - 0.00013 22.6 0.1 0.00045 20.8 0.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase tRNA-synt_1e PF01406.19 EGD92374.2 - 3.6e-114 381.2 0.0 5.9e-114 380.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGD92374.2 - 2e-05 23.5 0.3 0.07 11.9 0.2 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 EGD92374.2 - 0.00041 20.8 0.1 0.0011 19.4 0.1 1.8 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.18 EGD92374.2 - 0.048 12.6 0.0 0.68 8.8 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) GCD14 PF08704.10 EGD92375.1 - 3.5e-62 210.3 0.0 2.6e-61 207.5 0.0 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Rotamase_2 PF13145.6 EGD92375.1 - 4 8.3 9.4 0.11 13.3 2.7 1.8 2 0 0 2 2 2 0 PPIC-type PPIASE domain ABC_membrane PF00664.23 EGD92376.2 - 5.2e-74 249.3 32.2 9.4e-46 156.7 15.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGD92376.2 - 2.4e-54 183.5 0.0 2.7e-34 118.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGD92376.2 - 6.1e-09 35.6 1.2 0.0016 17.9 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGD92376.2 - 9.5e-09 34.9 0.4 0.0059 16.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGD92376.2 - 1e-07 32.5 0.1 0.00087 19.7 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EGD92376.2 - 4.2e-07 30.0 0.0 0.024 14.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EGD92376.2 - 1.8e-06 28.6 0.1 0.032 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGD92376.2 - 2.7e-06 27.4 0.0 0.037 13.9 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 EGD92376.2 - 2.1e-05 24.8 0.1 0.04 14.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGD92376.2 - 0.00021 21.3 0.0 1.3 9.2 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EGD92376.2 - 0.0004 20.3 0.1 0.22 11.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EGD92376.2 - 0.0017 18.5 0.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain Zeta_toxin PF06414.12 EGD92376.2 - 0.0019 17.5 0.0 0.97 8.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.18 EGD92376.2 - 0.004 16.5 0.1 0.18 11.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family ABC_ATPase PF09818.9 EGD92376.2 - 0.0068 15.3 0.7 0.017 14.0 0.1 1.9 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_30 PF13604.6 EGD92376.2 - 0.0092 15.7 0.2 7 6.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGD92376.2 - 0.011 15.3 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGD92376.2 - 0.011 15.4 0.9 8.9 6.0 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein G-alpha PF00503.20 EGD92376.2 - 0.016 14.4 0.0 0.45 9.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_25 PF13481.6 EGD92376.2 - 0.018 14.6 0.0 4.3 6.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EGD92376.2 - 0.018 15.2 0.0 9.8 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EGD92376.2 - 0.026 14.3 0.0 3.1 7.5 0.0 2.8 3 0 0 3 3 2 0 DEAD/DEAH box helicase AAA_10 PF12846.7 EGD92376.2 - 0.026 13.4 0.0 5.7 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Gtr1_RagA PF04670.12 EGD92376.2 - 0.04 13.3 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region SbcCD_C PF13558.6 EGD92376.2 - 0.063 13.5 0.3 0.23 11.7 0.3 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 EGD92376.2 - 0.076 13.0 0.0 36 4.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGD92376.2 - 0.078 13.5 0.0 18 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 EGD92376.2 - 0.095 11.7 0.0 0.66 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) TMEM100 PF16311.5 EGD92376.2 - 0.14 11.7 0.2 0.44 10.1 0.2 1.8 1 0 0 1 1 1 0 Transmembrane protein 100 APS_kinase PF01583.20 EGD92376.2 - 0.17 11.8 0.0 21 5.0 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Dynamin_N PF00350.23 EGD92376.2 - 0.19 11.7 2.2 18 5.4 0.1 3.2 4 0 0 4 4 3 0 Dynamin family NB-ARC PF00931.22 EGD92376.2 - 0.2 10.8 0.0 7.8 5.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain adh_short PF00106.25 EGD92377.1 - 9.6e-41 139.4 0.0 1.3e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGD92377.1 - 8.2e-27 94.3 0.0 1.1e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EGD92377.1 - 5.4e-07 29.3 0.0 7e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EGD92377.1 - 2.7e-06 27.4 0.0 6.7e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 KR domain PQ-loop PF04193.14 EGD92378.2 - 4.4e-33 112.9 2.8 1.8e-20 72.5 1.0 2.5 2 0 0 2 2 2 2 PQ loop repeat SGS PF05002.15 EGD92379.1 - 8.3e-28 96.3 9.2 7.3e-27 93.3 9.2 2.6 1 1 0 1 1 1 1 SGS domain CS PF04969.16 EGD92379.1 - 3.5e-18 66.4 0.0 7.1e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 EGD92379.1 - 2.3e-05 24.0 0.2 0.00038 20.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGD92379.1 - 0.0007 19.5 0.1 0.18 12.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGD92379.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 TPR repeat CcmH PF03918.14 EGD92379.1 - 0.057 12.7 0.1 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 Cytochrome C biogenesis protein TPR_16 PF13432.6 EGD92379.1 - 0.12 13.1 0.0 1.6 9.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ParB PF08775.10 EGD92379.1 - 3.7 8.1 7.3 0.5 10.8 2.8 1.8 2 0 0 2 2 2 0 ParB family SQHop_cyclase_C PF13243.6 EGD92380.2 - 1.1e-39 136.5 0.0 1.4e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 EGD92380.2 - 2.4e-23 81.6 2.8 3.1e-10 39.6 0.0 4.7 5 0 0 5 5 5 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EGD92380.2 - 1.3e-07 31.0 0.1 0.0039 16.3 0.0 3.5 2 1 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain Pec_lyase PF09492.10 EGD92380.2 - 3e-06 26.8 0.2 0.026 13.9 0.0 3.5 2 1 1 3 3 3 3 Pectic acid lyase TED_complement PF07678.14 EGD92380.2 - 0.0023 17.0 0.1 0.045 12.8 0.1 2.7 2 1 1 3 3 3 1 A-macroglobulin TED domain Ank_2 PF12796.7 EGD92382.2 - 8.4e-33 112.8 9.7 7.9e-11 42.4 0.4 5.2 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGD92382.2 - 3.6e-29 100.7 6.2 3.1e-10 40.4 0.5 6.9 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGD92382.2 - 8.9e-24 81.0 13.3 2.7e-05 24.2 0.0 10.8 11 0 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 EGD92382.2 - 1.5e-21 76.1 2.6 4.3e-10 39.6 0.1 6.9 5 2 3 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 EGD92382.2 - 3.6e-17 62.0 12.2 5.9e-06 26.5 0.1 7.7 9 1 0 9 9 9 3 Ankyrin repeat F-box-like PF12937.7 EGD92382.2 - 2e-05 24.4 0.1 3.9e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGD92382.2 - 3.1e-05 23.7 0.2 5.9e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 F-box domain eIF-6 PF01912.18 EGD92383.1 - 2.6e-79 265.2 0.7 3.2e-79 264.9 0.7 1.1 1 0 0 1 1 1 1 eIF-6 family SRR1 PF07985.12 EGD92384.1 - 4.1e-09 36.3 0.0 7.1e-08 32.4 0.0 2.6 2 0 0 2 2 2 1 SRR1 Zn_clus PF00172.18 EGD92385.1 - 0.00013 22.0 8.1 0.00032 20.8 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 EGD92386.2 - 5.4e-44 151.0 0.0 6.6e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase_Tyr PF07714.17 EGD92388.1 - 1.3e-13 50.8 0.0 1.8e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGD92388.1 - 3.5e-12 46.2 0.0 7.3e-12 45.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGD92388.1 - 0.0069 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGD92388.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGD92388.1 - 0.033 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PHO4 PF01384.20 EGD92389.1 - 3.5e-110 368.2 6.9 5.4e-110 367.6 6.9 1.3 1 1 0 1 1 1 1 Phosphate transporter family Aminotran_1_2 PF00155.21 EGD92390.2 - 3.8e-42 144.8 0.0 4.6e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGD92390.2 - 3.9e-11 42.1 0.0 4.9e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGD92390.2 - 2.1e-10 40.1 0.0 3e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGD92390.2 - 1.2e-05 24.7 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EGD92390.2 - 0.0073 14.9 0.0 0.0097 14.5 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Glyco_transf_22 PF03901.17 EGD92393.2 - 5e-30 105.1 7.0 6e-30 104.8 7.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3488 PF11992.8 EGD92393.2 - 0.0041 16.1 2.9 0.0063 15.5 2.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3488) DUF420 PF04238.12 EGD92393.2 - 0.11 12.8 0.7 0.11 12.8 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF420) Skp1 PF01466.19 EGD92394.1 - 3e-28 97.7 0.5 4.8e-28 97.0 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EGD92394.1 - 1.7e-24 85.7 0.2 4.2e-24 84.5 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DFF-C PF09033.10 EGD92394.1 - 0.044 13.7 0.1 0.081 12.8 0.0 1.5 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain Ribosomal_L39 PF00832.20 EGD92395.2 - 1.7e-14 53.1 0.9 2.1e-14 52.8 0.9 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein ABC_membrane PF00664.23 EGD92396.1 - 8.8e-102 340.4 37.1 4.6e-52 177.4 12.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGD92396.1 - 5.9e-68 227.6 0.0 1.4e-32 113.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGD92396.1 - 5e-15 55.5 0.0 0.00016 21.2 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGD92396.1 - 2.2e-07 31.4 1.9 0.027 14.8 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGD92396.1 - 7.8e-07 29.1 0.0 0.0078 16.1 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 EGD92396.1 - 8.9e-07 28.6 1.0 0.0068 16.1 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGD92396.1 - 2.3e-06 27.9 1.3 0.076 13.3 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EGD92396.1 - 1.2e-05 25.3 1.0 0.62 9.8 0.0 4.1 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 EGD92396.1 - 2.8e-05 23.1 1.9 0.06 12.1 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 EGD92396.1 - 5.6e-05 22.9 2.6 0.39 10.4 0.3 3.6 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 EGD92396.1 - 9.3e-05 22.1 0.2 0.089 12.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EGD92396.1 - 0.00011 22.0 0.0 0.06 13.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EGD92396.1 - 0.00012 22.6 4.3 0.37 11.2 0.5 4.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGD92396.1 - 0.00022 21.2 0.1 0.088 12.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 EGD92396.1 - 0.00061 19.3 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 EGD92396.1 - 0.00091 19.2 0.2 1.1 9.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGD92396.1 - 0.002 18.7 0.0 1.8 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGD92396.1 - 0.0025 18.0 0.1 2.8 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EGD92396.1 - 0.0048 16.6 0.1 1.5 8.5 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EGD92396.1 - 0.0073 15.6 0.0 3.8 6.7 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 EGD92396.1 - 0.0075 16.0 0.0 3.5 7.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 EGD92396.1 - 0.015 15.0 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 EGD92396.1 - 0.016 15.6 0.0 4.6 7.7 0.0 3.0 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.6 EGD92396.1 - 0.022 15.0 5.1 5.4 7.3 0.4 4.1 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 EGD92396.1 - 0.038 14.2 0.9 6 7.1 0.1 2.8 3 0 0 3 3 2 0 AAA domain Cytidylate_kin PF02224.18 EGD92396.1 - 0.047 13.4 0.1 5.1 6.8 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase SAA PF00277.18 EGD92396.1 - 0.073 13.5 1.5 1.2 9.6 0.0 2.7 3 0 0 3 3 2 0 Serum amyloid A protein AAA_23 PF13476.6 EGD92396.1 - 0.076 13.5 9.5 1.5 9.3 0.0 4.3 4 1 0 4 4 4 0 AAA domain G-alpha PF00503.20 EGD92396.1 - 0.087 12.0 0.0 11 5.0 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit APS_kinase PF01583.20 EGD92396.1 - 0.096 12.6 0.0 3.5 7.5 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 EGD92396.1 - 0.13 12.7 0.2 46 4.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain VP4_helical PF17478.2 EGD92397.2 - 0.023 14.1 0.1 0.023 14.1 0.1 1.1 1 0 0 1 1 1 0 Rotavirus VP4 helical domain CLN3 PF02487.17 EGD92397.2 - 0.064 12.3 0.0 0.073 12.1 0.0 1.0 1 0 0 1 1 1 0 CLN3 protein MFS_1 PF07690.16 EGD92398.2 - 1.5e-46 159.0 38.9 5.7e-37 127.5 23.9 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGD92398.2 - 1.3e-05 24.3 15.9 0.00065 18.7 3.0 3.0 1 1 2 3 3 3 2 MFS_1 like family OATP PF03137.20 EGD92398.2 - 0.0022 16.4 9.7 0.003 15.9 0.1 2.7 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EGD92398.2 - 0.0047 15.4 1.4 0.0047 15.4 1.4 2.4 2 1 0 2 2 2 1 Transmembrane secretion effector Asp-Al_Ex PF06826.12 EGD92398.2 - 0.0054 16.6 7.1 0.0054 16.6 7.1 3.2 2 1 1 3 3 3 2 Predicted Permease Membrane Region DUF1286 PF06939.11 EGD92398.2 - 0.0086 16.3 0.3 0.058 13.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1286) MFS_4 PF06779.14 EGD92398.2 - 4.7 6.4 25.4 1.7 7.9 5.1 3.6 2 2 2 4 4 4 0 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 EGD92402.1 - 5.1e-17 61.8 62.5 3.8e-10 39.2 19.5 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGD92402.1 - 0.00025 19.6 23.9 0.00035 19.1 23.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EGD92403.1 - 5.7e-18 65.0 50.8 5.5e-12 45.3 30.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Transferase PF02458.15 EGD92405.1 - 0.00055 18.7 0.0 0.0006 18.6 0.0 1.0 1 0 0 1 1 1 1 Transferase family Methyltransf_2 PF00891.18 EGD92406.1 - 3.2e-29 101.7 0.0 4.6e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGD92406.1 - 0.00083 19.3 0.1 0.003 17.5 0.0 1.8 2 0 0 2 2 2 1 Dimerisation domain Trp_DMAT PF11991.8 EGD92408.1 - 8.8e-110 367.5 0.1 1.7e-109 366.6 0.0 1.4 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase DUF1413 PF07205.11 EGD92408.1 - 0.085 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) Fungal_trans PF04082.18 EGD92409.1 - 5e-18 65.1 0.0 7.6e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGD92409.1 - 1.2e-08 34.9 8.5 2.5e-08 33.9 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 EGD92409.1 - 0.043 12.3 0.0 0.064 11.7 0.0 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Zn_clus PF00172.18 EGD92410.1 - 4.5e-07 29.9 11.4 4.5e-07 29.9 11.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.23 EGD92413.1 - 8.7e-15 54.7 3.6 1.6e-14 53.8 3.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGD92413.1 - 0.0023 18.0 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Transgly_assoc PF04226.13 EGD92413.1 - 0.02 15.1 4.6 0.02 15.1 4.6 1.8 2 0 0 2 2 2 0 Transglycosylase associated protein F-box-like PF12937.7 EGD92414.2 - 0.042 13.7 0.1 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 F-box-like PRANC PF09372.10 EGD92414.2 - 0.077 13.3 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 PRANC domain Pkinase PF00069.25 EGD92418.2 - 0.0016 17.8 0.1 0.0017 17.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Mgm101p PF06420.12 EGD92422.2 - 9.9e-88 292.1 0.0 1.1e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 PEPCK_ATP PF01293.20 KFL60090.1 - 5e-17 61.7 0.0 7.1e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF1100 PF06500.11 KFL60090.1 - 0.034 13.0 0.1 0.044 12.6 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) PEPCK_ATP PF01293.20 KFL60091.1 - 2.8e-160 534.1 0.0 3.3e-160 533.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KFL60091.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFL60091.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 KFL60092.1 - 3e-59 199.4 0.1 3.7e-59 199.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFL60092.1 - 2.8e-14 53.4 0.0 3.5e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFL60092.1 - 1.9e-11 43.8 0.0 2.4e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFL60092.1 - 2.1e-11 43.6 1.8 2.3e-07 30.3 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFL60092.1 - 4.8e-11 42.4 0.0 6.3e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFL60092.1 - 1.1e-09 38.0 0.0 1.4e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFL60092.1 - 0.00022 21.3 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFL60092.1 - 0.025 13.9 0.3 0.04 13.2 0.1 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Androgen_recep PF02166.16 KFL60093.1 - 2 7.1 14.9 2.8 6.7 14.9 1.2 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 KFL60094.1 - 0.00095 19.3 10.4 0.00095 19.3 10.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 KFL60094.1 - 0.033 12.9 17.5 0.04 12.6 17.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FHIPEP PF00771.20 KFL60094.1 - 0.06 11.8 0.1 0.07 11.6 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family Spt20 PF12090.8 KFL60094.1 - 0.39 10.3 10.4 0.58 9.7 10.4 1.2 1 0 0 1 1 1 0 Spt20 family Chromo_shadow PF01393.19 KFL60099.1 - 1.8e-20 72.8 0.1 6.3e-16 58.2 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFL60099.1 - 2.1e-15 56.3 0.2 4.7e-15 55.2 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SURF2 PF05477.11 KFL60099.1 - 8.7 6.0 10.8 6 6.5 0.2 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Chromo PF00385.24 KFL60100.1 - 1.9e-15 56.5 0.2 4.3e-15 55.4 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KFL60100.1 - 2.7e-12 46.6 0.0 1.1e-07 31.9 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain SURF2 PF05477.11 KFL60100.1 - 9.9 5.8 11.2 5.2 6.7 0.3 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Chromo_shadow PF01393.19 KFL60101.1 - 1.9e-18 66.3 0.0 3.7e-16 58.9 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFL60101.1 - 8.1e-10 38.5 0.1 1.5e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KFL60102.1 - 1.8e-18 66.3 0.0 3.6e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFL60102.1 - 7.9e-10 38.5 0.1 1.4e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NTP_transferase PF00483.23 KFL60103.1 - 1.4e-22 80.5 0.0 1.9e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KFL60103.1 - 8e-09 34.9 7.4 3.7e-06 26.5 0.1 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KFL60103.1 - 3.2e-05 24.3 0.0 4.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KFL60103.1 - 0.063 13.0 2.0 0.48 10.2 0.0 3.1 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 KFL60103.1 - 0.17 11.6 0.0 0.56 9.9 0.0 1.7 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase HgmA PF04209.13 KFL60104.1 - 3.8e-199 661.7 0.0 4.4e-199 661.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Aminotran_1_2 PF00155.21 KFL60106.1 - 2.7e-33 115.7 0.0 3.2e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFL60106.1 - 0.077 11.5 0.0 0.097 11.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BHD_3 PF10405.9 KFL60107.1 - 2.4e-29 101.5 0.1 6.4e-29 100.2 0.1 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 KFL60107.1 - 4e-28 97.9 0.0 7e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 KFL60107.1 - 8.7e-20 70.3 0.1 2e-19 69.1 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KFL60107.1 - 4.2e-16 59.6 2.5 5.5e-16 59.3 0.8 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 CENP-F_leu_zip PF10473.9 KFL60108.1 - 7.3e-05 22.8 22.9 7.3e-05 22.8 22.9 9.4 1 1 7 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KFL60108.1 - 0.0012 18.5 157.5 0.56 9.7 38.7 5.3 1 1 4 5 5 5 4 Intermediate filament protein Tropomyosin_1 PF12718.7 KFL60108.1 - 0.0038 17.4 28.9 0.0038 17.4 28.9 9.8 1 1 9 10 10 10 5 Tropomyosin like Csm1_N PF18504.1 KFL60108.1 - 0.012 15.9 5.8 0.012 15.9 5.8 16.7 6 3 11 18 18 18 0 Csm1 N-terminal domain DUF3287 PF11690.8 KFL60108.1 - 0.16 11.7 2.8 0.61 9.8 0.2 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF3287) CENP-F_leu_zip PF10473.9 KFL60109.1 - 1.9e-05 24.7 20.8 1.9e-05 24.7 20.8 9.2 1 1 7 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KFL60109.1 - 0.0019 17.9 158.2 0.28 10.7 37.9 5.2 1 1 3 4 4 4 3 Intermediate filament protein Tropomyosin_1 PF12718.7 KFL60109.1 - 0.0045 17.1 29.2 0.0045 17.1 29.2 9.6 1 1 9 10 10 10 5 Tropomyosin like FlxA PF14282.6 KFL60109.1 - 0.01 15.8 9.9 0.01 15.8 9.9 12.1 3 2 9 12 12 12 0 FlxA-like protein Csm1_N PF18504.1 KFL60109.1 - 0.012 16.0 5.8 0.012 16.0 5.8 16.2 5 3 11 17 17 17 0 Csm1 N-terminal domain DUF3287 PF11690.8 KFL60109.1 - 0.16 11.7 2.8 0.6 9.8 0.2 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF3287) DUF3584 PF12128.8 KFL60109.1 - 3.2 5.2 178.2 0.028 11.9 41.8 4.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) Pox_A_type_inc PF04508.12 KFL60109.1 - 9.7 6.2 25.6 1.1 9.2 0.1 8.2 10 0 0 10 10 10 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.9 KFL60110.1 - 1.9e-05 24.7 20.8 1.9e-05 24.7 20.8 9.2 1 1 7 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KFL60110.1 - 0.0019 17.9 158.2 0.28 10.7 37.9 5.2 1 1 3 4 4 4 3 Intermediate filament protein Tropomyosin_1 PF12718.7 KFL60110.1 - 0.0045 17.1 29.2 0.0045 17.1 29.2 9.6 1 1 9 10 10 10 5 Tropomyosin like FlxA PF14282.6 KFL60110.1 - 0.01 15.8 9.9 0.01 15.8 9.9 12.1 3 2 9 12 12 12 0 FlxA-like protein Csm1_N PF18504.1 KFL60110.1 - 0.012 16.0 5.8 0.012 16.0 5.8 16.2 5 3 11 17 17 17 0 Csm1 N-terminal domain DUF3287 PF11690.8 KFL60110.1 - 0.16 11.7 2.8 0.6 9.8 0.2 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF3287) DUF3584 PF12128.8 KFL60110.1 - 3.2 5.2 178.2 0.028 11.9 41.8 4.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) Pox_A_type_inc PF04508.12 KFL60110.1 - 9.7 6.2 25.6 1.1 9.2 0.1 8.2 10 0 0 10 10 10 0 Viral A-type inclusion protein repeat E1_dh PF00676.20 KFL60111.1 - 5.6e-91 304.6 0.2 6.6e-91 304.4 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KFL60111.1 - 0.00042 20.1 0.2 0.0017 18.2 0.2 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KFL60111.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 KFL60111.1 - 0.044 12.6 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 XFP N-terminal domain RRM_1 PF00076.22 KFL60112.1 - 0.00015 21.5 0.0 0.00047 19.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.6 KFL60112.1 - 0.0024 17.6 0.7 0.0043 16.8 0.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF533 PF04391.12 KFL60112.1 - 0.02 14.5 0.1 0.06 12.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Complex1_30kDa PF00329.19 KFL60113.1 - 1.3e-43 148.5 0.1 1.7e-43 148.1 0.1 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Abhydrolase_3 PF07859.13 KFL60115.1 - 1.5e-53 181.8 0.2 1.9e-53 181.4 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFL60115.1 - 7e-08 32.2 0.0 6.3e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KFL60115.1 - 0.014 14.9 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase COesterase PF00135.28 KFL60115.1 - 0.12 11.3 0.2 0.21 10.4 0.2 1.4 1 1 0 1 1 1 0 Carboxylesterase family ARPC4 PF05856.12 KFL60116.1 - 1.2e-74 249.5 4.7 1.3e-74 249.3 4.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Zn_clus PF00172.18 KFL60119.1 - 8.7e-09 35.4 7.3 1.2e-08 34.9 7.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KFL60120.1 - 8.2e-09 35.4 7.3 1.2e-08 34.9 7.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1690 PF07956.11 KFL60122.1 - 6.1e-39 133.6 5.2 3e-19 69.8 2.4 2.0 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Rootletin PF15035.6 KFL60122.1 - 0.015 15.4 1.0 0.18 11.8 0.3 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Hexokinase_2 PF03727.16 KFL60123.1 - 1.7e-73 247.0 0.0 2.6e-73 246.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KFL60123.1 - 4.6e-71 238.9 0.0 7.1e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase zf-C2HC5 PF06221.13 KFL60123.1 - 3.2e-20 71.9 6.6 6.2e-20 70.9 6.6 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type YhdB PF14148.6 KFL60123.1 - 0.18 12.0 0.1 0.41 10.8 0.1 1.5 1 0 0 1 1 1 0 YhdB-like protein Tropomodulin PF03250.14 KFL60123.1 - 0.73 9.9 8.0 4.6 7.3 3.5 2.4 1 1 1 2 2 2 0 Tropomodulin Gly-zipper_Omp PF13488.6 KFL60123.1 - 2.7 8.0 5.4 5 7.2 1.5 2.4 2 0 0 2 2 2 0 Glycine zipper RNase_PH PF01138.21 KFL60125.1 - 2.7e-14 53.8 0.3 3.8e-13 50.1 0.3 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 vATP-synt_E PF01991.18 KFL60127.1 - 4.5e-42 143.7 13.5 5.3e-42 143.5 13.5 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit 4PPT_N PF17837.1 KFL60127.1 - 0.054 13.6 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain DUF4288 PF14119.6 KFL60127.1 - 2.2 8.7 5.5 2.8 8.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) Pkinase PF00069.25 KFL60129.1 - 9.1e-09 35.1 0.1 2.1e-08 33.8 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60129.1 - 0.00013 21.3 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFL60129.1 - 0.00026 21.0 0.1 0.00054 19.9 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL60129.1 - 0.00057 19.3 0.0 0.00099 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFL60129.1 - 0.0055 16.3 0.0 0.02 14.5 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KFL60129.1 - 0.025 13.4 0.1 0.038 12.8 0.1 1.3 1 1 0 1 1 1 0 Fungal protein kinase Img2 PF05046.14 KFL60130.1 - 2.4e-19 69.4 0.0 3.7e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ArsA_ATPase PF02374.15 KFL60131.1 - 1e-110 369.7 0.0 1.3e-110 369.4 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KFL60131.1 - 1.1e-13 51.4 0.2 4.3e-12 46.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KFL60131.1 - 1.8e-12 47.4 0.0 3.4e-12 46.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 KFL60131.1 - 6.6e-06 25.8 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 KFL60131.1 - 7.9e-06 25.5 0.8 0.00018 21.0 0.1 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KFL60131.1 - 1.8e-05 24.5 0.2 0.00065 19.4 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KFL60131.1 - 9.2e-05 22.0 0.0 0.00028 20.4 0.0 1.7 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 KFL60131.1 - 0.056 12.9 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 KFL60131.1 - 0.075 12.2 0.0 0.2 10.8 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KFL60131.1 - 0.16 12.5 0.0 0.9 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFL60131.1 - 0.21 11.2 0.1 0.73 9.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Nop PF01798.18 KFL60133.1 - 9.6e-84 280.4 0.5 9.6e-84 280.4 0.5 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFL60133.1 - 5.6e-05 23.5 0.1 5.6e-05 23.5 0.1 3.0 4 0 0 4 4 4 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.16 KFL60134.1 - 2.6e-94 316.5 0.1 3.1e-94 316.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit vATP-synt_AC39 PF01992.16 KFL60135.1 - 1.2e-82 278.2 0.4 1.3e-82 278.0 0.4 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Mrx7 PF10906.8 KFL60138.1 - 1.1e-11 44.8 0.0 2.1e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 MIOREX complex component 7 eIF3_p135 PF12807.7 KFL60139.1 - 0.042 13.9 1.1 2.1 8.3 0.1 2.1 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit 135 Zn_clus PF00172.18 KFL60143.1 - 1.4e-08 34.7 8.1 1.4e-08 34.7 8.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFL60143.1 - 1.9e-05 23.6 0.5 2.9e-05 23.1 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF948 PF06103.11 KFL60144.1 - 0.00076 19.7 50.3 0.13 12.6 0.0 13.6 9 4 4 14 14 14 4 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KFL60144.1 - 0.0037 17.3 50.0 0.074 13.1 0.0 12.3 7 4 5 13 13 13 5 Protein of unknown function (DUF1664) HALZ PF02183.18 KFL60144.1 - 0.32 11.2 10.7 2.3 8.5 2.7 4.9 5 0 0 5 5 5 0 Homeobox associated leucine zipper SCO1-SenC PF02630.14 KFL60144.1 - 3.7 7.5 7.0 19 5.2 0.0 4.8 4 1 0 5 5 5 0 SCO1/SenC Ribosomal_L27e PF01777.18 KFL60145.1 - 6e-37 125.9 3.1 7.5e-37 125.6 3.1 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KFL60145.1 - 0.0013 18.6 0.1 0.0046 16.9 0.1 1.9 1 0 0 1 1 1 1 KOW motif Ribosomal_L27e PF01777.18 KFL60146.1 - 2.1e-38 130.5 3.6 2.7e-38 130.2 3.6 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KFL60146.1 - 0.0012 18.7 0.1 0.0042 17.0 0.1 2.0 2 0 0 2 2 2 1 KOW motif Ribosomal_L27e PF01777.18 KFL60147.1 - 2.1e-38 130.6 3.6 2.5e-38 130.3 3.6 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KFL60147.1 - 0.0012 18.7 0.2 0.004 17.0 0.1 2.0 2 0 0 2 2 2 1 KOW motif DUF2157 PF09925.9 KFL60151.1 - 0.00071 19.4 0.1 0.00071 19.4 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2157) Glypican PF01153.19 KFL60153.1 - 1.2 7.8 4.0 1.5 7.5 4.0 1.1 1 0 0 1 1 1 0 Glypican Nop14 PF04147.12 KFL60153.1 - 4.6 5.3 8.4 5.2 5.2 8.4 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KFL60153.1 - 5.5 6.2 8.1 7.2 5.8 8.1 1.1 1 0 0 1 1 1 0 NOA36 protein CRC_subunit PF08624.10 KFL60154.1 - 1.5e-33 116.1 0.0 2.3e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CAP_N PF01213.19 KFL60155.1 - 2.2 7.7 3.2 2.7 7.4 3.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TBP PF00352.21 KFL60156.1 - 6.7e-67 221.5 0.1 1.2e-32 111.7 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFL60156.1 - 8.1e-05 22.7 0.0 0.27 11.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KFL60156.1 - 0.17 11.7 0.1 0.84 9.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) TBP PF00352.21 KFL60157.1 - 1.8e-67 223.3 0.1 9.3e-33 112.0 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFL60157.1 - 5.5e-05 23.2 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KFL60157.1 - 0.13 12.1 0.1 0.69 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) TBP PF00352.21 KFL60158.1 - 1.8e-67 223.3 0.1 9.3e-33 112.0 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFL60158.1 - 5.5e-05 23.2 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KFL60158.1 - 0.13 12.1 0.1 0.69 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) TBP PF00352.21 KFL60159.1 - 1.8e-67 223.3 0.1 9.3e-33 112.0 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFL60159.1 - 5.5e-05 23.2 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KFL60159.1 - 0.13 12.1 0.1 0.69 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) ETF_QO PF05187.13 KFL60160.1 - 2.7e-24 85.3 0.0 4.3e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KFL60160.1 - 0.046 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFL60160.1 - 0.063 13.9 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GalKase_gal_bdg PF10509.9 KFL60162.1 - 6.2e-19 67.3 0.0 1.4e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 KFL60162.1 - 2.4e-15 56.7 0.0 5.9e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KFL60162.1 - 1.7e-13 50.6 2.1 3.3e-13 49.6 2.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain DED PF01335.21 KFL60162.1 - 0.071 13.4 0.2 0.19 12.1 0.2 1.8 1 0 0 1 1 1 0 Death effector domain Turandot PF07240.11 KFL60162.1 - 0.13 12.3 0.0 7.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Ras PF00071.22 KFL60163.1 - 2.4e-50 170.3 0.0 2.8e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL60163.1 - 1.3e-22 80.3 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL60163.1 - 1.1e-06 28.3 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFL60163.1 - 0.0049 16.3 0.0 0.0054 16.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFL60163.1 - 0.011 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFL60163.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KFL60163.1 - 0.11 12.9 0.1 0.33 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KFL60163.1 - 0.11 12.2 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KFL60163.1 - 0.21 11.4 0.1 0.43 10.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Ras PF00071.22 KFL60164.1 - 2.4e-50 170.3 0.0 2.8e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL60164.1 - 1.3e-22 80.3 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL60164.1 - 1.1e-06 28.3 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFL60164.1 - 0.0049 16.3 0.0 0.0054 16.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFL60164.1 - 0.011 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFL60164.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KFL60164.1 - 0.11 12.9 0.1 0.33 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KFL60164.1 - 0.11 12.2 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KFL60164.1 - 0.21 11.4 0.1 0.43 10.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system adh_short PF00106.25 KFL60166.1 - 4.6e-33 114.3 1.4 5.4e-33 114.1 1.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFL60166.1 - 3.3e-26 92.3 1.4 4.1e-26 92.0 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFL60166.1 - 2.1e-10 40.8 0.3 2.7e-10 40.5 0.3 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFL60166.1 - 0.0016 18.3 0.3 0.0019 18.1 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DDE_Tnp_1 PF01609.21 KFL60166.1 - 0.021 14.4 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain AdoHcyase_NAD PF00670.21 KFL60166.1 - 0.025 14.7 1.1 0.043 13.9 0.9 1.6 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_zinc_N PF00107.26 KFL60166.1 - 0.037 14.0 1.6 0.27 11.2 1.6 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 KFL60166.1 - 0.039 13.1 0.7 0.14 11.2 0.7 1.9 1 1 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFL60166.1 - 0.039 13.3 0.0 0.047 13.1 0.0 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFL60166.1 - 0.042 13.0 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 KFL60166.1 - 0.1 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFL60166.1 - 0.11 12.5 0.2 0.32 11.1 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_RFF PF18321.1 KFL60166.1 - 0.64 10.5 3.2 0.7 10.4 1.8 1.8 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain adh_short_C2 PF13561.6 KFL60167.1 - 2.2e-17 63.4 0.0 2.4e-08 33.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFL60167.1 - 8.3e-07 28.7 0.1 1.2e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase HMG_CoA_synt_C PF08540.10 KFL60173.1 - 5.5e-103 344.4 0.3 6.9e-103 344.1 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60173.1 - 3.8e-96 320.0 0.1 6.4e-96 319.2 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60174.1 - 5.5e-103 344.4 0.3 6.9e-103 344.1 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60174.1 - 3.8e-96 320.0 0.1 6.4e-96 319.2 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60175.1 - 5.5e-103 344.4 0.3 6.9e-103 344.1 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60175.1 - 3.8e-96 320.0 0.1 6.4e-96 319.2 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_N PF01154.17 KFL60176.1 - 3.2e-96 320.2 0.1 5.4e-96 319.4 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60176.1 - 1.6e-84 283.8 0.3 2.2e-84 283.4 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60177.1 - 3.2e-96 320.2 0.1 5.4e-96 319.4 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60177.1 - 1.6e-84 283.8 0.3 2.2e-84 283.4 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60178.1 - 3.2e-96 320.2 0.1 5.4e-96 319.4 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60178.1 - 1.6e-84 283.8 0.3 2.2e-84 283.4 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_C PF08540.10 KFL60179.1 - 4.1e-103 344.8 0.3 5e-103 344.6 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60179.1 - 1.2e-68 230.4 0.3 2.1e-68 229.6 0.3 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60180.1 - 4.1e-103 344.8 0.3 5e-103 344.6 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60180.1 - 1.2e-68 230.4 0.3 2.1e-68 229.6 0.3 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60181.1 - 4.1e-103 344.8 0.3 5e-103 344.6 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60181.1 - 1.2e-68 230.4 0.3 2.1e-68 229.6 0.3 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60182.1 - 1.2e-84 284.3 0.3 1.6e-84 283.8 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60182.1 - 9.7e-69 230.7 0.3 1.7e-68 229.9 0.3 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60183.1 - 1.2e-84 284.3 0.3 1.6e-84 283.8 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60183.1 - 9.7e-69 230.7 0.3 1.7e-68 229.9 0.3 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60184.1 - 1.2e-84 284.3 0.3 1.6e-84 283.8 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60184.1 - 9.7e-69 230.7 0.3 1.7e-68 229.9 0.3 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60185.1 - 3e-103 345.3 0.3 3.6e-103 345.0 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60185.1 - 4.2e-48 163.5 0.8 7.9e-48 162.6 0.8 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60186.1 - 3e-103 345.3 0.3 3.6e-103 345.0 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60186.1 - 4.2e-48 163.5 0.8 7.9e-48 162.6 0.8 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60187.1 - 3e-103 345.3 0.3 3.6e-103 345.0 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60187.1 - 4.2e-48 163.5 0.8 7.9e-48 162.6 0.8 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60188.1 - 3e-103 345.3 0.3 3.6e-103 345.0 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60188.1 - 4.2e-48 163.5 0.8 7.9e-48 162.6 0.8 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60189.1 - 3e-103 345.3 0.3 3.6e-103 345.0 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60189.1 - 4.2e-48 163.5 0.8 7.9e-48 162.6 0.8 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60190.1 - 3e-103 345.3 0.3 3.6e-103 345.0 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60190.1 - 4.2e-48 163.5 0.8 7.9e-48 162.6 0.8 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFL60191.1 - 8.8e-85 284.7 0.3 1.1e-84 284.3 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60191.1 - 3.5e-48 163.8 0.8 6.6e-48 162.9 0.8 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.8 KFL60191.1 - 0.17 11.6 0.2 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.10 KFL60192.1 - 8.8e-85 284.7 0.3 1.1e-84 284.3 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60192.1 - 3.5e-48 163.8 0.8 6.6e-48 162.9 0.8 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.8 KFL60192.1 - 0.17 11.6 0.2 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.10 KFL60193.1 - 8.8e-85 284.7 0.3 1.1e-84 284.3 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60193.1 - 3.5e-48 163.8 0.8 6.6e-48 162.9 0.8 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.8 KFL60193.1 - 0.17 11.6 0.2 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.10 KFL60194.1 - 8.8e-85 284.7 0.3 1.1e-84 284.3 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFL60194.1 - 3.5e-48 163.8 0.8 6.6e-48 162.9 0.8 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.8 KFL60194.1 - 0.17 11.6 0.2 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) PGM_PMM_III PF02880.16 KFL60195.1 - 4.6e-26 91.2 0.0 7.8e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KFL60195.1 - 2.9e-15 56.8 0.0 6.7e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KFL60195.1 - 4.2e-09 36.5 0.0 9.3e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Arg_repressor PF01316.21 KFL60199.1 - 0.0046 16.7 0.2 0.0068 16.1 0.2 1.2 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain TPP_enzyme_M PF00205.22 KFL60201.1 - 1e-20 73.8 0.0 2.9e-20 72.4 0.0 1.7 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KFL60201.1 - 3.9e-15 55.9 0.0 8.1e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 KFL60201.1 - 0.037 13.6 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain E1_dh PF00676.20 KFL60201.1 - 0.062 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component TPP_enzyme_M PF00205.22 KFL60202.1 - 9.6e-21 74.0 0.0 2.6e-20 72.5 0.0 1.7 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KFL60202.1 - 3.6e-15 56.1 0.0 7.6e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 KFL60202.1 - 0.036 13.7 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain E1_dh PF00676.20 KFL60202.1 - 0.059 12.3 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component TPP_enzyme_M PF00205.22 KFL60203.1 - 5.9e-21 74.6 0.0 1.8e-20 73.1 0.0 1.8 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KFL60203.1 - 6.3e-11 42.3 0.1 1.4e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 KFL60203.1 - 0.027 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain APH PF01636.23 KFL60204.1 - 0.0009 19.2 0.0 0.0016 18.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.23 KFL60205.1 - 0.00068 19.6 0.0 0.0012 18.9 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Lgl_C PF08596.10 KFL60206.1 - 4.4e-99 331.8 0.0 1.1e-98 330.5 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KFL60206.1 - 0.13 13.2 5.3 9.8 7.2 0.1 4.6 6 0 0 6 6 6 0 WD domain, G-beta repeat Stm1_N PF09598.10 KFL60209.1 - 1.5e-14 54.6 4.4 1.5e-14 54.6 4.4 2.3 1 1 1 2 2 2 1 Stm1 Ribosomal_L32p PF01783.23 KFL60210.1 - 2.3 8.5 5.6 4 7.8 5.6 1.4 1 0 0 1 1 1 0 Ribosomal L32p protein family tRNA-synt_1c PF00749.21 KFL60212.1 - 1.2e-100 336.5 0.0 1.5e-100 336.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFL60212.1 - 3.4e-39 134.5 0.2 5.3e-39 133.9 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 KFL60212.1 - 0.0024 18.0 0.0 0.19 11.9 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFL60212.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFL60212.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HCO3_cotransp PF00955.21 KFL60213.1 - 2.9e-36 125.4 15.0 4.2e-22 78.7 0.3 3.1 2 1 1 3 3 3 3 HCO3- transporter family BCHF PF07284.11 KFL60213.1 - 0.27 11.2 6.1 0.046 13.7 1.4 2.2 2 0 0 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) HCO3_cotransp PF00955.21 KFL60214.1 - 1.9e-10 40.2 0.1 2.3e-10 40.0 0.1 1.0 1 0 0 1 1 1 1 HCO3- transporter family LRR_6 PF13516.6 KFL60217.1 - 2.7e-13 48.8 18.2 0.27 11.4 0.0 11.2 12 0 0 12 12 12 3 Leucine Rich repeat F-box-like PF12937.7 KFL60217.1 - 4.8e-09 36.0 1.7 4.8e-09 36.0 1.7 3.2 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KFL60217.1 - 1.4e-08 34.9 10.5 2.1 8.9 0.0 7.4 3 2 7 10 10 10 6 Leucine Rich repeats (2 copies) F-box PF00646.33 KFL60217.1 - 0.0014 18.5 9.1 0.0033 17.3 2.3 3.5 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.6 KFL60217.1 - 0.014 15.2 5.9 2.8 7.8 0.0 5.1 4 1 2 6 6 6 0 Leucine rich repeat DUF1699 PF08004.11 KFL60217.1 - 0.017 14.8 0.1 0.21 11.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) CbbQ_C PF08406.10 KFL60217.1 - 0.051 13.8 0.2 31 4.9 0.0 3.5 3 0 0 3 3 3 0 CbbQ/NirQ/NorQ C-terminal Recep_L_domain PF01030.24 KFL60217.1 - 0.088 12.9 1.3 39 4.4 0.1 3.9 2 1 3 5 5 5 0 Receptor L domain Preseq_ALAS PF09029.10 KFL60217.1 - 0.18 12.3 0.9 0.71 10.4 0.1 2.3 2 1 1 3 3 3 0 5-aminolevulinate synthase presequence LRR_1 PF00560.33 KFL60217.1 - 1.7 9.5 14.8 66 4.7 0.1 8.4 9 2 0 9 9 9 0 Leucine Rich Repeat CCDC73 PF15818.5 KFL60219.1 - 0.15 9.9 0.2 0.16 9.8 0.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family Metallophos PF00149.28 KFL60220.1 - 8e-15 55.9 0.6 1.2e-14 55.3 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFL60220.1 - 6.5e-07 29.7 0.5 1.7e-05 25.0 0.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KFL60220.1 - 4.7e-05 22.8 0.0 0.0089 15.4 0.0 2.5 2 1 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily MutL PF13941.6 KFL60220.1 - 0.027 13.1 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 MutL protein Metallophos_3 PF14582.6 KFL60221.1 - 0.0018 17.6 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily MBOAT PF03062.19 KFL60223.1 - 2.2e-06 27.3 4.8 2.9e-06 26.9 4.8 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Methyltransf_23 PF13489.6 KFL60224.1 - 0.016 15.0 0.0 0.032 14.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KFL60224.1 - 0.032 13.8 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 KFL60224.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 KFL60225.1 - 6.8e-134 446.6 0.0 2.7e-66 223.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KFL60225.1 - 1.1e-109 367.2 0.0 1.1e-35 123.2 0.0 5.4 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.25 KFL60225.1 - 7.3e-33 112.7 0.1 9.5e-12 45.1 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFL60225.1 - 0.0049 17.8 0.0 8.4 7.5 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain HpaB PF03241.13 KFL60225.1 - 0.014 14.5 0.0 0.069 12.2 0.0 2.0 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Cyclophil_like2 PF18050.1 KFL60225.1 - 0.033 14.1 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Cyclophilin-like family Beta-lactamase PF00144.24 KFL60226.1 - 5.6e-21 75.1 0.0 6.2e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KFL60227.1 - 2e-09 37.9 0.1 3e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Importin_rep_6 PF18829.1 KFL60227.1 - 0.05 13.7 2.6 0.08 13.1 2.6 1.4 1 0 0 1 1 1 0 Importin repeat 6 Beta-lactamase PF00144.24 KFL60227.1 - 0.09 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase Nop14 PF04147.12 KFL60227.1 - 0.12 10.6 1.5 0.12 10.5 1.5 1.0 1 0 0 1 1 1 0 Nop14-like family Imm5 PF14423.6 KFL60227.1 - 0.12 12.6 2.5 0.18 12.1 2.5 1.2 1 0 0 1 1 1 0 Immunity protein Imm5 Astro_capsid_p PF12226.8 KFL60227.1 - 0.15 11.1 2.5 0.18 10.9 2.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.10 KFL60227.1 - 0.18 12.2 11.3 0.31 11.5 11.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KFL60227.1 - 0.32 10.3 5.2 0.41 9.9 5.2 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 KFL60227.1 - 2.3 7.3 8.6 3 6.9 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) KH_1 PF00013.29 KFL60231.1 - 5.6e-30 103.0 4.2 2.7e-17 62.4 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 KFL60231.1 - 0.001 18.8 5.9 0.08 12.8 0.2 2.5 2 1 0 2 2 2 2 KH domain KH_5 PF13184.6 KFL60231.1 - 0.0024 17.9 1.0 0.13 12.3 0.1 2.4 2 0 0 2 2 2 1 NusA-like KH domain KH_4 PF13083.6 KFL60231.1 - 0.029 14.2 3.4 0.62 10.0 0.2 2.3 2 0 0 2 2 2 0 KH domain Lactonase PF10282.9 KFL60233.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Ank_2 PF12796.7 KFL60234.1 - 1.8e-24 86.1 0.8 7.3e-13 48.9 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFL60234.1 - 2e-20 72.6 0.8 1.6e-09 37.8 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFL60234.1 - 1.7e-14 54.0 0.0 3e-07 30.9 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFL60234.1 - 1.3e-13 50.7 0.8 0.0011 19.4 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KFL60234.1 - 6.1e-12 44.6 0.7 0.00014 22.0 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 KFL60235.1 - 1.4e-24 86.5 0.8 6.9e-13 49.0 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFL60235.1 - 1.6e-20 72.9 0.8 1.5e-09 37.9 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFL60235.1 - 1.4e-14 54.2 0.0 2.8e-07 30.9 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFL60235.1 - 1.1e-13 50.9 0.8 0.001 19.4 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KFL60235.1 - 4.9e-12 44.9 0.7 0.00014 22.0 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat CDO_I PF05995.12 KFL60238.1 - 1.7e-31 108.8 0.1 3e-29 101.5 0.1 2.1 1 1 1 2 2 2 2 Cysteine dioxygenase type I PCO_ADO PF07847.12 KFL60238.1 - 6.9e-08 32.2 0.0 8.5e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO CDO_I PF05995.12 KFL60239.1 - 8e-36 122.9 0.0 9.5e-36 122.6 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KFL60239.1 - 7.5e-08 32.1 0.0 8.7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO Glyco_transf_8 PF01501.20 KFL60240.1 - 5.3e-21 75.3 0.2 1.2e-20 74.1 0.2 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 HEAT PF02985.22 KFL60242.1 - 7.4e-37 122.2 8.2 0.011 15.9 0.1 10.4 10 0 0 10 10 10 9 HEAT repeat HEAT_2 PF13646.6 KFL60242.1 - 9.4e-28 96.4 2.1 6.3e-10 39.3 0.0 5.9 2 1 2 5 5 5 5 HEAT repeats HEAT_EZ PF13513.6 KFL60242.1 - 1.6e-14 54.0 2.9 4.3e-05 23.9 0.0 7.4 6 2 2 8 8 8 2 HEAT-like repeat Cnd1 PF12717.7 KFL60242.1 - 4.9e-11 42.9 5.8 0.0018 18.4 0.4 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFL60242.1 - 3.4e-10 40.4 1.7 0.00036 21.1 0.2 5.6 3 2 4 7 7 7 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KFL60242.1 - 1.2e-07 30.7 3.1 4e-07 29.0 1.9 2.5 1 1 1 2 2 2 1 Adaptin N terminal region RTP1_C1 PF10363.9 KFL60242.1 - 0.00055 20.1 3.7 0.67 10.1 0.2 4.1 3 1 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KFL60242.1 - 0.003 17.1 2.2 2.4 7.7 0.1 4.2 4 1 1 5 5 5 1 CLASP N terminal Arm PF00514.23 KFL60242.1 - 0.026 14.6 3.9 1.5 9.0 0.0 4.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat M11L PF11099.8 KFL60242.1 - 0.088 13.1 0.2 38 4.5 0.0 3.3 2 1 1 3 3 3 0 Apoptosis regulator M11L like TetR_C_16 PF17920.1 KFL60242.1 - 0.11 12.7 0.2 13 6.1 0.0 2.9 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain IFRD PF05004.13 KFL60242.1 - 0.18 10.9 0.4 1.3 8.1 0.0 2.5 2 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Ecm29 PF13001.7 KFL60242.1 - 0.51 9.0 4.0 9 4.8 0.1 3.2 3 1 1 4 4 4 0 Proteasome stabiliser API5 PF05918.11 KFL60242.1 - 1.3 7.8 6.2 0.61 8.8 1.7 2.6 3 1 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) HEAT PF02985.22 KFL60243.1 - 3.9e-38 126.2 9.5 0.0098 16.1 0.1 11.2 11 0 0 11 11 11 10 HEAT repeat HEAT_2 PF13646.6 KFL60243.1 - 2.8e-30 104.6 0.3 5.5e-10 39.5 0.0 6.6 3 1 2 6 6 6 6 HEAT repeats HEAT_EZ PF13513.6 KFL60243.1 - 1.7e-15 57.2 4.5 9.7e-05 22.8 0.0 7.7 6 2 2 8 8 8 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFL60243.1 - 2.1e-12 47.5 2.9 0.00042 20.8 0.1 6.6 4 2 3 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFL60243.1 - 2.8e-08 34.0 7.1 0.01 15.9 0.0 4.8 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFL60243.1 - 3.6e-05 22.5 5.6 0.00096 17.8 1.8 3.0 2 1 1 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.8 KFL60243.1 - 0.0045 16.6 1.4 1.7 8.2 0.1 4.0 3 2 1 4 4 4 1 CLASP N terminal TetR_C_16 PF17920.1 KFL60243.1 - 0.034 14.4 0.5 12 6.2 0.0 3.5 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain M11L PF11099.8 KFL60243.1 - 0.07 13.4 0.2 38 4.5 0.0 3.3 2 1 0 3 3 3 0 Apoptosis regulator M11L like Arm PF00514.23 KFL60243.1 - 0.087 12.9 6.1 1.3 9.1 0.0 4.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat IFRD PF05004.13 KFL60243.1 - 0.14 11.2 0.5 1.3 8.0 0.0 2.8 2 2 1 3 3 3 0 Interferon-related developmental regulator (IFRD) Ecm29 PF13001.7 KFL60243.1 - 0.47 9.1 3.3 21 3.6 0.1 3.4 3 1 1 4 4 4 0 Proteasome stabiliser tRNA_synthFbeta PF17759.1 KFL60244.1 - 8.5e-35 120.1 0.0 1.3e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KFL60244.1 - 3.3e-29 100.9 0.2 4.4e-28 97.3 0.1 2.2 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KFL60244.1 - 8.2e-25 87.5 0.1 1.6e-24 86.5 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KFL60244.1 - 1.2e-18 67.2 0.0 1.8e-14 53.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2740 PF10872.8 KFL60244.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) tRNA_synthFbeta PF17759.1 KFL60245.1 - 2.5e-49 167.6 0.0 3.6e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 KFL60245.1 - 7.4e-25 87.6 0.1 1.5e-24 86.7 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KFL60245.1 - 9e-15 54.7 0.0 1.7e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase B5 domain DUF2740 PF10872.8 KFL60245.1 - 0.055 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) tRNA_synthFbeta PF17759.1 KFL60246.1 - 2.5e-49 167.6 0.0 3.6e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 KFL60246.1 - 7.4e-25 87.6 0.1 1.5e-24 86.7 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KFL60246.1 - 9e-15 54.7 0.0 1.7e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase B5 domain DUF2740 PF10872.8 KFL60246.1 - 0.055 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) tRNA_synthFbeta PF17759.1 KFL60247.1 - 2.5e-49 167.6 0.0 3.6e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 KFL60247.1 - 7.4e-25 87.6 0.1 1.5e-24 86.7 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KFL60247.1 - 9e-15 54.7 0.0 1.7e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase B5 domain DUF2740 PF10872.8 KFL60247.1 - 0.055 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) tRNA_synthFbeta PF17759.1 KFL60248.1 - 6.4e-35 120.5 0.0 9.9e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 KFL60248.1 - 5.9e-25 87.9 0.1 1.2e-24 86.9 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KFL60248.1 - 7.9e-15 54.9 0.0 1.4e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase B5 domain DUF2740 PF10872.8 KFL60248.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) tRNA_synthFbeta PF17759.1 KFL60249.1 - 6.4e-35 120.5 0.0 9.9e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 KFL60249.1 - 5.9e-25 87.9 0.1 1.2e-24 86.9 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KFL60249.1 - 7.9e-15 54.9 0.0 1.4e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase B5 domain DUF2740 PF10872.8 KFL60249.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) tRNA_synthFbeta PF17759.1 KFL60250.1 - 6.4e-35 120.5 0.0 9.9e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 KFL60250.1 - 5.9e-25 87.9 0.1 1.2e-24 86.9 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KFL60250.1 - 7.9e-15 54.9 0.0 1.4e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase B5 domain DUF2740 PF10872.8 KFL60250.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) NT-C2 PF10358.9 KFL60251.1 - 5.4e-28 97.5 0.0 7.1e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins ERG4_ERG24 PF01222.17 KFL60252.1 - 3.9e-127 424.6 2.3 4.4e-127 424.4 2.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KFL60252.1 - 0.00017 21.2 1.1 0.00036 20.1 0.3 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) Ferlin_C PF16165.5 KFL60252.1 - 1 9.3 3.1 0.53 10.2 0.3 1.9 2 0 0 2 2 2 0 Ferlin C-terminus Fungal_trans PF04082.18 KFL60253.1 - 1.2e-24 86.8 1.1 4.9e-24 84.8 0.0 2.6 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFL60253.1 - 2.4e-06 27.6 8.1 4.6e-06 26.7 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KFL60253.1 - 0.00019 21.6 31.0 0.0003 20.9 15.7 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF2202 PF09968.9 KFL60253.1 - 0.29 11.0 4.1 0.66 9.8 4.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) DDHD PF02862.17 KFL60253.1 - 0.53 10.4 16.2 0.19 11.9 7.2 2.3 2 0 0 2 2 2 0 DDHD domain PBP1_TM PF14812.6 KFL60253.1 - 1.5 9.2 4.6 28 5.2 2.9 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt20 PF12090.8 KFL60253.1 - 1.6 8.3 45.7 0.055 13.1 27.3 2.4 2 0 0 2 2 2 0 Spt20 family Band_3_cyto PF07565.13 KFL60253.1 - 9.5 5.9 16.6 0.24 11.2 5.6 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Glyco_hydro_3_C PF01915.22 KFL60255.1 - 3.4e-52 177.4 0.0 6.3e-52 176.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFL60255.1 - 1.9e-35 122.8 0.0 4e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFL60255.1 - 2.2e-12 46.9 0.0 4.1e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Herpes_UL42 PF02282.16 KFL60257.1 - 0.098 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) tRNA-synt_1e PF01406.19 KFL60259.1 - 1.7e-63 214.8 0.0 2.1e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.21 KFL60259.1 - 0.074 11.9 0.0 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Fer4_12 PF13353.6 KFL60259.1 - 0.088 13.1 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain Pkinase PF00069.25 KFL60261.1 - 1.2e-63 215.0 0.0 1.4e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60261.1 - 5.1e-35 121.0 0.0 6.3e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFL60261.1 - 3.1e-07 30.0 0.0 4.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFL60261.1 - 9e-05 21.4 0.0 0.00014 20.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFL60261.1 - 0.082 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DnaJ PF00226.31 KFL60262.1 - 4.7e-27 93.9 3.6 6.8e-27 93.4 1.2 2.4 3 0 0 3 3 2 1 DnaJ domain TPR_1 PF00515.28 KFL60262.1 - 9.6e-27 91.7 3.8 4.2e-07 29.5 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFL60262.1 - 2.4e-25 86.5 5.3 6.3e-07 29.0 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFL60262.1 - 9.4e-18 64.5 5.4 1.4e-05 25.5 0.1 5.3 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFL60262.1 - 5.4e-17 61.0 4.2 0.00015 22.3 0.0 6.9 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFL60262.1 - 2.7e-15 55.8 5.6 8.8e-06 25.3 0.0 5.7 6 1 1 7 7 6 3 TPR repeat TPR_8 PF13181.6 KFL60262.1 - 5.1e-15 54.4 1.5 0.0028 17.7 0.0 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFL60262.1 - 3.4e-14 51.8 1.9 0.024 14.6 0.0 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFL60262.1 - 1.5e-13 51.2 0.6 0.00091 19.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFL60262.1 - 8.3e-12 44.6 3.0 0.00043 20.5 0.2 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFL60262.1 - 2.1e-10 40.7 3.7 0.011 16.1 0.0 4.9 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFL60262.1 - 7.4e-10 38.8 0.1 0.0012 19.0 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFL60262.1 - 5.3e-09 36.1 4.6 0.001 19.6 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFL60262.1 - 3.6e-07 30.3 0.3 0.051 13.8 0.1 3.2 2 1 1 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KFL60262.1 - 1.7e-06 28.0 0.9 0.5 10.5 0.0 4.0 1 1 3 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 KFL60262.1 - 2e-05 23.9 1.8 0.006 15.8 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFL60262.1 - 0.00012 21.9 4.0 1.4 8.9 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFL60262.1 - 0.0035 17.8 1.1 15 6.6 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KFL60262.1 - 0.009 16.5 1.6 27 5.2 0.1 4.2 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 KFL60262.1 - 0.021 15.1 2.3 6.6 7.1 0.1 3.0 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFL60262.1 - 0.029 13.8 0.4 0.65 9.3 0.0 2.5 2 1 0 3 3 3 0 MalT-like TPR region MIT PF04212.18 KFL60262.1 - 0.035 14.2 1.0 0.64 10.1 0.0 3.3 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain Coatomer_E PF04733.14 KFL60262.1 - 0.036 13.5 0.1 6.4 6.1 0.0 2.5 2 1 0 2 2 2 0 Coatomer epsilon subunit DUF3856 PF12968.7 KFL60262.1 - 0.049 13.7 0.3 42 4.2 0.6 4.3 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) HHH_8 PF14716.6 KFL60262.1 - 0.084 13.3 2.7 0.89 10.0 0.1 3.3 4 0 0 4 4 3 0 Helix-hairpin-helix domain TPR_21 PF09976.9 KFL60262.1 - 0.092 12.4 2.5 5.4 6.7 0.0 3.8 2 2 3 5 5 5 0 Tetratricopeptide repeat-like domain MAS20 PF02064.15 KFL60262.1 - 0.11 12.6 0.4 1.1 9.4 0.0 2.8 4 0 0 4 4 3 0 MAS20 protein import receptor DUF2856 PF11043.8 KFL60262.1 - 0.13 12.3 0.6 8.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) HemY_N PF07219.13 KFL60262.1 - 0.18 12.0 1.6 23 5.2 0.0 3.5 2 1 1 3 3 3 0 HemY protein N-terminus Sugar_tr PF00083.24 KFL60265.1 - 4.4e-28 98.4 10.4 8.2e-21 74.4 10.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFL60265.1 - 9.3e-09 34.7 11.8 1.2e-08 34.3 11.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL60266.1 - 1.9e-19 69.9 6.3 2e-19 69.8 6.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFL60266.1 - 2.8e-06 26.5 6.6 3e-06 26.4 6.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.11 KFL60266.1 - 0.0077 16.0 2.9 0.01 15.6 2.9 1.3 1 0 0 1 1 1 1 7TM receptor with intracellular HD hydrolase Ras PF00071.22 KFL60267.1 - 3.9e-23 81.8 0.0 5e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL60267.1 - 1.4e-06 28.5 0.0 2.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase XFP PF03894.15 KFL60269.1 - 2.6e-40 138.0 0.0 3.1e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase SH3_9 PF14604.6 KFL60269.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain GFO_IDH_MocA PF01408.22 KFL60270.1 - 8.4e-10 39.5 0.3 3.5e-09 37.5 0.3 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold E1-E2_ATPase PF00122.20 KFL60272.1 - 1.6e-19 70.2 0.0 3.9e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFL60272.1 - 3.3e-13 50.4 1.5 4.7e-06 27.0 3.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFL60272.1 - 0.0034 17.2 0.2 0.024 14.4 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFL60272.1 - 0.0053 16.8 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) S6PP PF05116.13 KFL60272.1 - 0.067 12.7 0.7 0.25 10.8 0.0 2.2 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase E1-E2_ATPase PF00122.20 KFL60273.1 - 1.5e-19 70.2 0.0 3.7e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFL60273.1 - 2.8e-13 50.6 1.5 4.2e-06 27.2 3.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFL60273.1 - 0.0032 17.3 0.2 0.024 14.4 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFL60273.1 - 0.0051 16.9 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) S6PP PF05116.13 KFL60273.1 - 0.062 12.8 0.7 0.24 10.9 0.0 2.2 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Rbsn PF11464.8 KFL60274.1 - 1e-17 63.6 0.6 2e-17 62.6 0.6 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE PF01363.21 KFL60274.1 - 4.1e-17 62.1 4.9 6.7e-17 61.4 4.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger YqaH PF17448.2 KFL60274.1 - 0.011 16.1 0.2 0.022 15.1 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized YqaH-like TMF_TATA_bd PF12325.8 KFL60274.1 - 0.036 14.3 0.5 0.036 14.3 0.5 1.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FYVE_2 PF02318.16 KFL60274.1 - 0.041 14.1 5.8 0.33 11.2 6.1 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger Seryl_tRNA_N PF02403.22 KFL60274.1 - 0.042 14.1 1.4 0.12 12.6 1.4 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain C6_DPF PF10170.9 KFL60274.1 - 0.057 13.8 0.3 0.15 12.5 0.3 1.6 1 0 0 1 1 1 0 Cysteine-rich domain DDE_Tnp_Tn3 PF01526.17 KFL60274.1 - 0.078 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Tn3 transposase DDE domain RE_BstXI PF09552.10 KFL60274.1 - 0.083 12.1 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease Nairovirus_M PF07948.11 KFL60274.1 - 0.19 9.9 0.6 0.34 9.1 0.3 1.4 1 1 1 2 2 2 0 Nairovirus M polyprotein-like Val_tRNA-synt_C PF10458.9 KFL60274.1 - 0.24 11.7 1.4 34 4.8 0.1 2.9 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Rbsn PF11464.8 KFL60275.1 - 1e-17 63.6 0.6 2e-17 62.6 0.6 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE PF01363.21 KFL60275.1 - 4.1e-17 62.1 4.9 6.7e-17 61.4 4.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger YqaH PF17448.2 KFL60275.1 - 0.011 16.1 0.2 0.022 15.1 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized YqaH-like TMF_TATA_bd PF12325.8 KFL60275.1 - 0.036 14.3 0.5 0.036 14.3 0.5 1.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FYVE_2 PF02318.16 KFL60275.1 - 0.041 14.1 5.8 0.33 11.2 6.1 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger Seryl_tRNA_N PF02403.22 KFL60275.1 - 0.042 14.1 1.4 0.12 12.6 1.4 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain C6_DPF PF10170.9 KFL60275.1 - 0.057 13.8 0.3 0.15 12.5 0.3 1.6 1 0 0 1 1 1 0 Cysteine-rich domain DDE_Tnp_Tn3 PF01526.17 KFL60275.1 - 0.078 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Tn3 transposase DDE domain RE_BstXI PF09552.10 KFL60275.1 - 0.083 12.1 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease Nairovirus_M PF07948.11 KFL60275.1 - 0.19 9.9 0.6 0.34 9.1 0.3 1.4 1 1 1 2 2 2 0 Nairovirus M polyprotein-like Val_tRNA-synt_C PF10458.9 KFL60275.1 - 0.24 11.7 1.4 34 4.8 0.1 2.9 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Rbsn PF11464.8 KFL60276.1 - 1e-17 63.6 0.6 2e-17 62.6 0.6 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE PF01363.21 KFL60276.1 - 4.1e-17 62.1 4.9 6.7e-17 61.4 4.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger YqaH PF17448.2 KFL60276.1 - 0.011 16.1 0.2 0.022 15.1 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized YqaH-like TMF_TATA_bd PF12325.8 KFL60276.1 - 0.036 14.3 0.5 0.036 14.3 0.5 1.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FYVE_2 PF02318.16 KFL60276.1 - 0.041 14.1 5.8 0.33 11.2 6.1 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger Seryl_tRNA_N PF02403.22 KFL60276.1 - 0.042 14.1 1.4 0.12 12.6 1.4 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain C6_DPF PF10170.9 KFL60276.1 - 0.057 13.8 0.3 0.15 12.5 0.3 1.6 1 0 0 1 1 1 0 Cysteine-rich domain DDE_Tnp_Tn3 PF01526.17 KFL60276.1 - 0.078 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Tn3 transposase DDE domain RE_BstXI PF09552.10 KFL60276.1 - 0.083 12.1 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease Nairovirus_M PF07948.11 KFL60276.1 - 0.19 9.9 0.6 0.34 9.1 0.3 1.4 1 1 1 2 2 2 0 Nairovirus M polyprotein-like Val_tRNA-synt_C PF10458.9 KFL60276.1 - 0.24 11.7 1.4 34 4.8 0.1 2.9 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Rbsn PF11464.8 KFL60277.1 - 9.2e-18 63.7 0.6 1.9e-17 62.7 0.6 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE PF01363.21 KFL60277.1 - 3.8e-17 62.2 4.9 6.2e-17 61.5 4.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger YqaH PF17448.2 KFL60277.1 - 0.0097 16.2 0.2 0.021 15.1 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized YqaH-like TMF_TATA_bd PF12325.8 KFL60277.1 - 0.034 14.4 0.5 0.034 14.4 0.5 2.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 KFL60277.1 - 0.038 14.2 1.4 0.11 12.7 1.4 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DDE_Tnp_Tn3 PF01526.17 KFL60277.1 - 0.074 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Tn3 transposase DDE domain RE_BstXI PF09552.10 KFL60277.1 - 0.077 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease Nairovirus_M PF07948.11 KFL60277.1 - 0.18 10.0 0.6 0.32 9.2 0.3 1.4 1 1 1 2 2 2 0 Nairovirus M polyprotein-like Val_tRNA-synt_C PF10458.9 KFL60277.1 - 0.19 12.0 1.3 32 4.9 0.1 2.9 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm FYVE_2 PF02318.16 KFL60277.1 - 0.46 10.7 9.4 0.42 10.8 6.5 2.3 2 1 1 3 3 3 0 FYVE-type zinc finger Rbsn PF11464.8 KFL60278.1 - 9.2e-18 63.7 0.6 1.9e-17 62.7 0.6 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE PF01363.21 KFL60278.1 - 3.8e-17 62.2 4.9 6.2e-17 61.5 4.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger YqaH PF17448.2 KFL60278.1 - 0.0097 16.2 0.2 0.021 15.1 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized YqaH-like TMF_TATA_bd PF12325.8 KFL60278.1 - 0.034 14.4 0.5 0.034 14.4 0.5 2.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 KFL60278.1 - 0.038 14.2 1.4 0.11 12.7 1.4 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DDE_Tnp_Tn3 PF01526.17 KFL60278.1 - 0.074 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Tn3 transposase DDE domain RE_BstXI PF09552.10 KFL60278.1 - 0.077 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease Nairovirus_M PF07948.11 KFL60278.1 - 0.18 10.0 0.6 0.32 9.2 0.3 1.4 1 1 1 2 2 2 0 Nairovirus M polyprotein-like Val_tRNA-synt_C PF10458.9 KFL60278.1 - 0.19 12.0 1.3 32 4.9 0.1 2.9 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm FYVE_2 PF02318.16 KFL60278.1 - 0.46 10.7 9.4 0.42 10.8 6.5 2.3 2 1 1 3 3 3 0 FYVE-type zinc finger Rbsn PF11464.8 KFL60279.1 - 9.2e-18 63.7 0.6 1.9e-17 62.7 0.6 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE PF01363.21 KFL60279.1 - 3.8e-17 62.2 4.9 6.2e-17 61.5 4.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger YqaH PF17448.2 KFL60279.1 - 0.0097 16.2 0.2 0.021 15.1 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized YqaH-like TMF_TATA_bd PF12325.8 KFL60279.1 - 0.034 14.4 0.5 0.034 14.4 0.5 2.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 KFL60279.1 - 0.038 14.2 1.4 0.11 12.7 1.4 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DDE_Tnp_Tn3 PF01526.17 KFL60279.1 - 0.074 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Tn3 transposase DDE domain RE_BstXI PF09552.10 KFL60279.1 - 0.077 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease Nairovirus_M PF07948.11 KFL60279.1 - 0.18 10.0 0.6 0.32 9.2 0.3 1.4 1 1 1 2 2 2 0 Nairovirus M polyprotein-like Val_tRNA-synt_C PF10458.9 KFL60279.1 - 0.19 12.0 1.3 32 4.9 0.1 2.9 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm FYVE_2 PF02318.16 KFL60279.1 - 0.46 10.7 9.4 0.42 10.8 6.5 2.3 2 1 1 3 3 3 0 FYVE-type zinc finger Rbsn PF11464.8 KFL60280.1 - 9.2e-18 63.7 0.6 1.9e-17 62.7 0.6 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE PF01363.21 KFL60280.1 - 3.8e-17 62.2 4.9 6.2e-17 61.5 4.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger YqaH PF17448.2 KFL60280.1 - 0.0097 16.2 0.2 0.021 15.1 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized YqaH-like TMF_TATA_bd PF12325.8 KFL60280.1 - 0.034 14.4 0.5 0.034 14.4 0.5 2.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 KFL60280.1 - 0.038 14.2 1.4 0.11 12.7 1.4 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DDE_Tnp_Tn3 PF01526.17 KFL60280.1 - 0.074 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Tn3 transposase DDE domain RE_BstXI PF09552.10 KFL60280.1 - 0.077 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease Nairovirus_M PF07948.11 KFL60280.1 - 0.18 10.0 0.6 0.32 9.2 0.3 1.4 1 1 1 2 2 2 0 Nairovirus M polyprotein-like Val_tRNA-synt_C PF10458.9 KFL60280.1 - 0.19 12.0 1.3 32 4.9 0.1 2.9 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm FYVE_2 PF02318.16 KFL60280.1 - 0.46 10.7 9.4 0.42 10.8 6.5 2.3 2 1 1 3 3 3 0 FYVE-type zinc finger EIF_2_alpha PF07541.12 KFL60282.1 - 1.4e-36 125.1 0.0 3.1e-36 124.0 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KFL60282.1 - 4.8e-10 39.6 0.6 9.2e-10 38.7 0.6 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Myb_DNA-bind_2 PF08914.11 KFL60282.1 - 0.13 12.4 0.1 0.34 11.1 0.1 1.7 1 0 0 1 1 1 0 Rap1 Myb domain DUF3638 PF12340.8 KFL60283.1 - 2.2e-31 108.9 0.0 3.9e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KFL60283.1 - 6e-15 54.3 0.1 1.1e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF3638 PF12340.8 KFL60284.1 - 1.8e-20 73.3 0.0 2.9e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) Palm_thioest PF02089.15 KFL60286.1 - 2e-81 273.4 0.0 3.2e-81 272.8 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KFL60286.1 - 0.045 13.1 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 KFL60286.1 - 0.049 13.3 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S10 PF00450.22 KFL60287.1 - 1e-47 163.5 4.4 1.4e-47 163.1 4.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 KFL60288.1 - 1e-24 87.8 0.0 1.2e-24 87.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase AlaDh_PNT_N PF05222.15 KFL60289.1 - 5.2e-28 98.0 0.0 6.8e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_N PF05222.15 KFL60290.1 - 4.8e-28 98.1 0.0 6.7e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_N PF05222.15 KFL60291.1 - 4.4e-28 98.3 0.0 5.8e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain BAR PF03114.18 KFL60292.1 - 1.2e-66 224.8 7.7 1.5e-66 224.5 7.7 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KFL60292.1 - 3.9e-13 48.8 0.0 8.1e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFL60292.1 - 1e-11 44.5 0.0 1.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFL60292.1 - 2.2e-07 30.4 0.1 6.6e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.10 KFL60292.1 - 0.11 12.1 5.4 3.3 7.2 2.2 2.2 2 0 0 2 2 2 0 Vps5 C terminal like BAR_3 PF16746.5 KFL60292.1 - 0.5 10.0 10.1 2.1 8.0 10.1 2.2 1 1 0 1 1 1 0 BAR domain of APPL family TMPIT PF07851.13 KFL60292.1 - 0.75 9.0 8.7 1.2 8.3 0.2 2.1 1 1 1 2 2 2 0 TMPIT-like protein APG6_N PF17675.1 KFL60292.1 - 2.6 8.6 10.8 12 6.4 5.0 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 KFL60292.1 - 3.2 7.9 12.1 0.97 9.5 0.6 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase BAR PF03114.18 KFL60293.1 - 2.3e-44 151.8 3.4 2.9e-44 151.5 3.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KFL60293.1 - 3.1e-13 49.1 0.0 6.4e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFL60293.1 - 8.9e-12 44.7 0.0 1.4e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFL60293.1 - 1.6e-07 30.9 0.1 5.2e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain ERG4_ERG24 PF01222.17 KFL60294.1 - 3.4e-14 52.4 0.3 4.2e-14 52.1 0.3 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Abhydrolase_6 PF12697.7 KFL60295.1 - 7.8e-05 23.4 0.3 9.6e-05 23.1 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KFL60295.1 - 0.0011 18.8 0.0 0.0015 18.3 0.0 1.3 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KFL60295.1 - 0.0077 15.8 0.0 0.0099 15.4 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KFL60295.1 - 0.032 13.5 0.2 0.071 12.4 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF829 PF05705.14 KFL60295.1 - 0.04 13.8 0.0 0.047 13.6 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) NB-ARC PF00931.22 KFL60296.1 - 3.8e-09 36.1 0.0 5.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KFL60296.1 - 2.5e-06 28.0 0.0 5.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFL60296.1 - 0.0011 19.3 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFL60296.1 - 0.028 14.4 0.0 4 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFL60296.1 - 0.047 13.6 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 KFL60296.1 - 0.048 13.1 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein ATPase PF06745.13 KFL60296.1 - 0.11 11.8 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 KaiC Vps23_core PF09454.10 KFL60297.1 - 4.3e-21 74.6 0.0 2.1e-20 72.4 0.0 2.0 2 0 0 2 2 2 1 Vps23 core domain UEV PF05743.13 KFL60297.1 - 9.3e-10 38.4 0.0 1.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain ADIP PF11559.8 KFL60297.1 - 0.025 14.7 2.2 0.039 14.1 2.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Paralemmin PF03285.15 KFL60297.1 - 0.056 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Paralemmin Snapin_Pallidin PF14712.6 KFL60297.1 - 0.12 12.8 0.7 0.2 12.1 0.7 1.3 1 0 0 1 1 1 0 Snapin/Pallidin AAA_13 PF13166.6 KFL60297.1 - 0.14 10.8 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 AAA domain Spidroin_N PF16763.5 KFL60297.1 - 0.17 11.9 0.7 0.3 11.1 0.7 1.3 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term TPR_MLP1_2 PF07926.12 KFL60297.1 - 0.2 11.7 1.1 2.6 8.1 0.1 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ACOX PF01756.19 KFL60297.1 - 0.35 10.4 1.3 5.9 6.4 0.8 2.1 2 0 0 2 2 2 0 Acyl-CoA oxidase Clat_adaptor_s PF01217.20 KFL60298.1 - 5.4e-37 126.9 2.0 6.4e-37 126.6 2.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 KFL60298.1 - 0.03 15.0 0.3 0.043 14.6 0.2 1.4 1 1 0 1 1 1 0 Pullulanase N1-terminal domain Zip PF02535.22 KFL60301.1 - 6.7e-58 196.5 11.1 4.1e-57 193.9 11.1 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 KFL60302.1 - 5.5e-53 180.3 13.0 3.6e-52 177.6 13.0 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter MFS_1 PF07690.16 KFL60303.1 - 2.6e-08 33.2 10.6 4.9e-08 32.3 10.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL60303.1 - 0.011 14.6 5.4 0.38 9.5 4.9 1.9 1 1 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.16 KFL60304.1 - 1.1e-16 60.7 13.4 1.5e-16 60.3 13.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFL60304.1 - 0.00014 21.3 4.1 0.00022 20.6 4.1 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB E1-E2_ATPase PF00122.20 KFL60305.1 - 4.1e-40 137.2 14.7 1.5e-31 109.3 0.0 3.8 3 1 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFL60305.1 - 4.9e-27 94.8 2.8 4.9e-27 94.8 2.8 2.7 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFL60305.1 - 1e-17 65.1 0.3 3.2e-14 53.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFL60305.1 - 8.3e-13 48.2 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFL60305.1 - 1.6e-05 24.7 1.5 1.6e-05 24.7 1.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KFL60305.1 - 0.0022 17.9 1.3 0.006 16.5 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) Cation_ATPase_N PF00690.26 KFL60305.1 - 0.071 12.8 1.6 0.55 10.0 1.0 2.6 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 KFL60306.1 - 9.6e-42 142.5 8.5 1.4e-31 109.4 0.0 3.3 2 1 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFL60306.1 - 4.7e-27 94.9 2.8 4.7e-27 94.9 2.8 2.6 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFL60306.1 - 9.7e-18 65.2 0.3 3.1e-14 53.8 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFL60306.1 - 8.1e-13 48.3 0.0 1.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFL60306.1 - 1.6e-05 24.8 1.5 1.6e-05 24.8 1.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KFL60306.1 - 0.0022 17.9 1.3 0.0059 16.5 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) E1-E2_ATPase PF00122.20 KFL60307.1 - 9.6e-42 142.5 8.5 1.4e-31 109.4 0.0 3.3 2 1 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFL60307.1 - 4.7e-27 94.9 2.8 4.7e-27 94.9 2.8 2.6 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFL60307.1 - 9.7e-18 65.2 0.3 3.1e-14 53.8 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFL60307.1 - 8.1e-13 48.3 0.0 1.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFL60307.1 - 1.6e-05 24.8 1.5 1.6e-05 24.8 1.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KFL60307.1 - 0.0022 17.9 1.3 0.0059 16.5 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) E1-E2_ATPase PF00122.20 KFL60308.1 - 5.9e-30 104.1 3.4 4.1e-26 91.6 2.3 3.3 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFL60308.1 - 4.1e-27 95.1 2.8 4.1e-27 95.1 2.8 2.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFL60308.1 - 8.1e-18 65.5 0.3 2.7e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFL60308.1 - 7.1e-13 48.5 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFL60308.1 - 1.5e-05 24.9 1.5 1.5e-05 24.9 1.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KFL60308.1 - 0.002 18.0 1.3 0.0053 16.7 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) E1-E2_ATPase PF00122.20 KFL60309.1 - 5.9e-30 104.1 3.4 4.1e-26 91.6 2.3 3.3 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFL60309.1 - 4.1e-27 95.1 2.8 4.1e-27 95.1 2.8 2.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFL60309.1 - 8.1e-18 65.5 0.3 2.7e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFL60309.1 - 7.1e-13 48.5 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFL60309.1 - 1.5e-05 24.9 1.5 1.5e-05 24.9 1.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KFL60309.1 - 0.002 18.0 1.3 0.0053 16.7 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) E1-E2_ATPase PF00122.20 KFL60310.1 - 5.9e-30 104.1 3.4 4.1e-26 91.6 2.3 3.3 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFL60310.1 - 4.1e-27 95.1 2.8 4.1e-27 95.1 2.8 2.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFL60310.1 - 8.1e-18 65.5 0.3 2.7e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFL60310.1 - 7.1e-13 48.5 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFL60310.1 - 1.5e-05 24.9 1.5 1.5e-05 24.9 1.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KFL60310.1 - 0.002 18.0 1.3 0.0053 16.7 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) E1-E2_ATPase PF00122.20 KFL60311.1 - 5.9e-30 104.1 3.4 4.1e-26 91.6 2.3 3.3 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFL60311.1 - 4.1e-27 95.1 2.8 4.1e-27 95.1 2.8 2.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFL60311.1 - 8.1e-18 65.5 0.3 2.7e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFL60311.1 - 7.1e-13 48.5 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFL60311.1 - 1.5e-05 24.9 1.5 1.5e-05 24.9 1.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KFL60311.1 - 0.002 18.0 1.3 0.0053 16.7 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) C1_1 PF00130.22 KFL60313.1 - 4.3e-16 58.5 5.2 6.3e-16 58.0 5.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFL60313.1 - 0.013 15.8 4.7 0.022 15.1 4.7 1.3 1 0 0 1 1 1 0 C1 domain FYVE PF01363.21 KFL60313.1 - 0.088 13.0 3.0 0.17 12.1 3.0 1.4 1 0 0 1 1 1 0 FYVE zinc finger SH3_1 PF00018.28 KFL60313.1 - 0.12 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 SH3 domain OrfB_Zn_ribbon PF07282.11 KFL60313.1 - 0.43 10.6 2.9 1.2 9.1 2.9 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_9 PF13901.6 KFL60313.1 - 5 7.1 11.2 2.1e+02 1.7 11.2 2.1 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon C1_1 PF00130.22 KFL60314.1 - 4.3e-16 58.5 5.2 6.3e-16 58.0 5.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFL60314.1 - 0.013 15.8 4.7 0.022 15.1 4.7 1.3 1 0 0 1 1 1 0 C1 domain FYVE PF01363.21 KFL60314.1 - 0.088 13.0 3.0 0.17 12.1 3.0 1.4 1 0 0 1 1 1 0 FYVE zinc finger SH3_1 PF00018.28 KFL60314.1 - 0.12 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 SH3 domain OrfB_Zn_ribbon PF07282.11 KFL60314.1 - 0.43 10.6 2.9 1.2 9.1 2.9 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_9 PF13901.6 KFL60314.1 - 5 7.1 11.2 2.1e+02 1.7 11.2 2.1 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon Glyco_hydro_72 PF03198.14 KFL60315.1 - 1.5e-122 408.8 4.1 1.8e-122 408.5 4.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KFL60315.1 - 7.7e-07 28.8 0.2 4.9e-06 26.2 0.2 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_72 PF03198.14 KFL60316.1 - 1.2e-87 294.1 2.3 1.5e-87 293.8 2.3 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KFL60316.1 - 0.0041 16.6 0.1 0.018 14.5 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Actin PF00022.19 KFL60317.1 - 0.00039 19.2 0.0 0.00051 18.8 0.0 1.2 1 0 0 1 1 1 1 Actin Actin PF00022.19 KFL60318.1 - 2.5e-22 79.0 0.0 1e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.13 KFL60318.1 - 8.6e-06 24.8 0.0 0.01 14.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 KFL60318.1 - 0.00011 21.6 0.2 0.21 10.7 0.1 2.2 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 KFL60318.1 - 0.067 13.6 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 Cell division protein FtsA Totivirus_coat PF05518.11 KFL60318.1 - 2.4 6.1 7.4 3.5 5.6 7.4 1.1 1 0 0 1 1 1 0 Totivirus coat protein RICTOR_N PF14664.6 KFL60319.1 - 2e-117 392.4 0.0 2.9e-117 391.8 0.0 1.2 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term HR1 PF02185.16 KFL60319.1 - 9.5e-15 54.5 10.5 9.5e-15 54.5 10.5 2.1 3 0 0 3 3 3 1 Hr1 repeat DLP_helical PF18709.1 KFL60319.1 - 0.017 14.4 1.0 0.03 13.5 1.0 1.3 1 0 0 1 1 1 0 Dynamin-like helical domain Uds1 PF15456.6 KFL60319.1 - 0.2 11.8 7.2 0.63 10.2 7.2 1.8 1 0 0 1 1 1 0 Up-regulated During Septation DUF724 PF05266.14 KFL60319.1 - 2.3 8.0 7.8 7.4 6.3 6.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) RICTOR_M PF14666.6 KFL60320.1 - 8.5e-38 128.3 1.7 5.6e-34 116.0 0.3 4.5 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KFL60320.1 - 9.2e-38 129.0 0.0 1.1e-36 125.5 0.0 2.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KFL60320.1 - 1.1e-29 102.4 1.5 1.3e-26 92.6 0.1 3.9 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.9 KFL60320.1 - 0.001 17.7 0.4 2 6.9 0.1 3.6 2 1 2 4 4 4 3 Proteasome non-ATPase 26S subunit PDH PF02153.17 KFL60321.1 - 0.00016 20.8 0.0 0.00025 20.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase PDH PF02153.17 KFL60322.1 - 0.00012 21.2 0.0 0.00015 20.8 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase PDH PF02153.17 KFL60323.1 - 0.00012 21.2 0.0 0.00015 20.8 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase PDH PF02153.17 KFL60324.1 - 0.00011 21.3 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase PDH PF02153.17 KFL60325.1 - 0.00011 21.3 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase PDH PF02153.17 KFL60326.1 - 0.00011 21.3 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase Adaptin_N PF01602.20 KFL60327.1 - 3e-40 138.3 1.2 3.3e-40 138.1 1.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFL60327.1 - 3.5e-35 121.4 2.0 1.1e-34 119.8 0.3 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFL60327.1 - 2.1e-12 46.2 0.5 0.0048 17.0 0.0 3.5 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.6 KFL60327.1 - 1.4e-10 41.4 0.5 2e-09 37.7 0.5 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 KFL60327.1 - 8.3e-06 26.2 1.5 0.17 12.4 0.1 3.2 2 1 1 3 3 3 2 HEAT-like repeat GHD PF17834.1 KFL60327.1 - 0.0047 16.9 0.0 0.072 13.1 0.1 2.3 2 0 0 2 2 2 1 Beta-sandwich domain in beta galactosidase Arm PF00514.23 KFL60327.1 - 0.01 15.9 1.2 12 6.1 0.0 3.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KFL60327.1 - 0.038 13.5 0.3 0.39 10.2 0.0 2.0 2 1 0 2 2 2 0 CLASP N terminal RasGEF_N_2 PF14663.6 KFL60327.1 - 0.082 13.3 0.1 1.8 9.0 0.0 2.4 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Adaptin_N PF01602.20 KFL60328.1 - 3.8e-65 220.4 2.3 4.4e-65 220.2 2.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFL60328.1 - 4.8e-11 43.0 1.1 8.5e-08 32.4 0.0 2.9 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFL60328.1 - 8.1e-05 22.9 0.6 0.77 10.2 0.1 2.9 2 0 0 2 2 2 2 HEAT repeats Atx10homo_assoc PF09759.9 KFL60328.1 - 0.013 15.5 0.0 8.7 6.4 0.0 2.7 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Importin_rep_4 PF18808.1 KFL60328.1 - 0.02 15.1 0.2 3.4 8.0 0.0 3.4 3 0 0 3 3 3 0 Importin repeat Arm PF00514.23 KFL60328.1 - 0.062 13.4 0.2 2.4 8.3 0.0 3.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Ribosomal_S17e PF00833.18 KFL60330.1 - 7.5e-60 200.2 0.5 9e-60 200.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S17e PF00833.18 KFL60331.1 - 3.9e-21 75.2 0.1 5.7e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal S17 MAP1B_neuraxin PF00414.17 KFL60332.1 - 0.16 11.6 0.2 0.41 10.3 0.2 1.8 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat DAHP_synth_1 PF00793.20 KFL60333.1 - 1.9e-80 269.7 0.0 2.2e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Rtf2 PF04641.12 KFL60334.1 - 5.3e-61 206.3 0.1 6.4e-61 206.0 0.1 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KFL60334.1 - 1.4e-09 37.6 0.0 0.00043 20.0 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KFL60334.1 - 0.00042 20.3 0.5 0.0023 17.9 0.0 2.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-NOSIP PF15906.5 KFL60334.1 - 0.0008 19.5 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 KFL60334.1 - 0.0059 16.5 0.2 0.014 15.3 0.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFL60334.1 - 0.023 14.5 0.1 0.064 13.1 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFL60334.1 - 0.038 13.9 0.7 0.51 10.2 0.3 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFL60334.1 - 0.088 13.2 0.7 0.2 12.0 0.2 1.9 2 0 0 2 2 2 0 Ring finger domain DUF2239 PF09998.9 KFL60334.1 - 0.11 12.2 0.0 8.3 6.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) CI-B14_5a PF07347.12 KFL60337.1 - 0.082 12.8 0.2 0.22 11.4 0.0 1.8 2 1 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) CI-B14_5a PF07347.12 KFL60338.1 - 0.076 12.9 0.2 0.2 11.6 0.0 1.8 2 1 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Hydantoinase_B PF02538.14 KFL60339.1 - 2.6e-142 474.8 0.0 4.1e-142 474.2 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KFL60339.1 - 1.7e-102 342.6 0.5 1.7e-102 342.6 0.5 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KFL60339.1 - 9.9e-60 201.3 1.0 3.4e-58 196.3 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_B PF02538.14 KFL60340.1 - 1.4e-112 376.8 0.0 2.2e-112 376.1 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KFL60340.1 - 1.4e-102 342.8 0.5 1.4e-102 342.8 0.5 1.9 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KFL60340.1 - 7.9e-60 201.6 1.0 3e-58 196.5 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KFL60341.1 - 1.2e-102 343.2 0.5 1.2e-102 343.2 0.5 1.9 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KFL60341.1 - 6.9e-60 201.8 1.0 2.5e-58 196.7 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_B PF02538.14 KFL60341.1 - 2.2e-56 191.4 0.1 3.6e-56 190.7 0.1 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase TIP41 PF04176.13 KFL60342.1 - 1.3e-70 236.4 0.0 1.5e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family TIP41 PF04176.13 KFL60343.1 - 9.6e-71 236.8 0.0 1.1e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.25 KFL60344.1 - 2.4e-70 236.9 0.0 2.8e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60344.1 - 7e-43 146.8 0.0 8.6e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFL60344.1 - 1.3e-07 31.3 0.0 2.2e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFL60344.1 - 9.2e-05 21.9 0.2 0.00015 21.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFL60344.1 - 0.0012 17.9 0.0 0.0015 17.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFL60344.1 - 0.011 15.3 0.1 0.036 13.7 0.1 1.8 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KFL60344.1 - 0.059 13.0 0.1 0.11 12.1 0.0 1.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFL60344.1 - 0.059 13.3 0.1 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFL60344.1 - 0.099 12.1 0.0 0.18 11.3 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_M76 PF09768.9 KFL60345.1 - 5.3e-71 237.9 2.4 6.5e-71 237.6 2.4 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KFL60345.1 - 0.0008 19.3 0.6 0.002 17.9 0.4 1.6 1 1 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 KFL60345.1 - 0.0096 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Effector protein CAF20 PF17052.5 KFL60345.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Cap associated factor Tox-MPTase2 PF15638.6 KFL60345.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 PALP PF00291.25 KFL60346.1 - 9.5e-37 127.0 0.0 1.3e-36 126.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KFL60346.1 - 9.6e-11 42.0 0.0 4.2e-07 30.3 0.0 3.1 4 0 0 4 4 4 2 CBS domain FIST PF08495.10 KFL60346.1 - 0.14 12.1 0.1 0.56 10.2 0.1 2.1 1 1 0 1 1 1 0 FIST N domain PALP PF00291.25 KFL60347.1 - 1.2e-31 110.3 0.1 1.4e-31 110.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KFL60347.1 - 1.3e-10 41.6 0.0 4e-07 30.4 0.0 2.8 3 0 0 3 3 3 2 CBS domain FIST PF08495.10 KFL60347.1 - 0.16 12.0 0.1 0.5 10.4 0.1 2.0 1 1 0 1 1 1 0 FIST N domain AA_kinase PF00696.28 KFL60348.1 - 9.4e-42 143.3 2.6 1.4e-41 142.7 2.6 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KFL60348.1 - 7e-12 45.1 0.0 6.5e-11 42.0 0.0 2.4 2 0 0 2 2 2 1 PUA domain AA_kinase PF00696.28 KFL60349.1 - 1.1e-32 113.6 0.1 1.4e-32 113.2 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KFL60349.1 - 2.5e-11 43.4 0.0 5.5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 PUA domain AA_kinase PF00696.28 KFL60350.1 - 1.1e-32 113.5 0.5 1.6e-32 113.1 0.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KFL60350.1 - 2.3e-11 43.5 0.0 5.1e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 PUA domain AA_kinase PF00696.28 KFL60351.1 - 6.6e-23 81.6 1.1 9.6e-23 81.0 1.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KFL60351.1 - 1.9e-11 43.8 0.0 3.5e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 PUA domain Ank_2 PF12796.7 KFL60352.1 - 2.1e-17 63.5 0.0 9.4e-12 45.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFL60352.1 - 5.1e-17 61.7 0.0 4.6e-09 36.4 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFL60352.1 - 1e-13 50.0 2.1 0.0095 16.4 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KFL60352.1 - 1.6e-13 50.9 0.1 0.00013 22.5 0.3 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFL60352.1 - 4.5e-12 45.8 0.4 0.0074 16.7 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat RseC_MucC PF04246.12 KFL60352.1 - 0.88 9.5 2.5 1.5 8.8 2.5 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC SHMT PF00464.19 KFL60354.1 - 2.4e-175 582.9 0.0 2.8e-175 582.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase SHMT PF00464.19 KFL60355.1 - 1.6e-136 455.1 0.0 1.9e-136 454.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase HA2 PF04408.23 KFL60359.1 - 2.2e-17 63.3 0.0 4e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFL60359.1 - 1.2e-06 28.8 0.0 2.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KFL60360.1 - 4.5e-05 23.7 0.1 9.7e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KFL60360.1 - 0.00074 18.9 0.0 0.0038 16.6 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family DEAD PF00270.29 KFL60360.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KFL60360.1 - 0.0013 17.9 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 KFL60360.1 - 0.0016 19.0 0.1 0.0047 17.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain DLIC PF05783.11 KFL60360.1 - 0.0023 16.8 0.7 0.2 10.5 0.4 2.1 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) ABC_tran PF00005.27 KFL60360.1 - 0.0055 17.2 0.4 0.07 13.7 0.1 2.3 1 1 2 3 3 3 1 ABC transporter AAA_29 PF13555.6 KFL60360.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KFL60360.1 - 0.021 14.2 0.0 0.063 12.6 0.0 1.7 2 0 0 2 2 2 0 KaiC Septin PF00735.18 KFL60360.1 - 0.059 12.6 0.1 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 KFL60360.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KFL60360.1 - 0.088 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3482 PF11981.8 KFL60360.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) AAA_19 PF13245.6 KFL60360.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFL60360.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF3824 PF12868.7 KFL60362.1 - 2.7e-14 54.1 25.4 2.7e-14 54.1 25.4 9.9 2 2 6 9 9 9 1 Domain of unknwon function (DUF3824) NDUF_B12 PF08122.12 KFL60362.1 - 0.0052 16.8 1.2 0.26 11.4 0.0 3.6 3 1 1 4 4 4 1 NADH-ubiquinone oxidoreductase B12 subunit family Transformer PF06495.11 KFL60362.1 - 0.0078 16.3 5.8 0.0078 16.3 5.8 6.9 3 3 2 6 6 6 1 Fruit fly transformer protein RskA PF10099.9 KFL60362.1 - 0.021 15.1 9.5 3.5 7.9 0.0 3.6 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF4473 PF14747.6 KFL60362.1 - 0.053 14.1 6.2 0.6 10.7 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) STALD PF18185.1 KFL60362.1 - 0.42 9.9 3.2 5.9 6.2 0.7 2.2 1 1 0 2 2 2 0 Sir2- and TIR-associating SLOG family GNAT_acetyltr_2 PF13718.6 KFL60362.1 - 8.9 5.6 7.2 3.2 7.1 0.2 2.5 2 0 0 2 2 2 0 GNAT acetyltransferase 2 DUF3824 PF12868.7 KFL60363.1 - 1e-14 55.5 24.2 1e-14 55.5 24.2 9.3 1 1 6 8 8 8 1 Domain of unknwon function (DUF3824) NDUF_B12 PF08122.12 KFL60363.1 - 0.0033 17.4 1.0 0.23 11.5 0.0 3.7 3 1 1 4 4 4 1 NADH-ubiquinone oxidoreductase B12 subunit family Transformer PF06495.11 KFL60363.1 - 0.0071 16.5 5.9 0.0071 16.5 5.9 7.2 3 3 3 7 7 7 1 Fruit fly transformer protein RskA PF10099.9 KFL60363.1 - 0.025 14.9 10.3 3.1 8.1 0.0 3.6 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF4473 PF14747.6 KFL60363.1 - 0.04 14.5 6.2 0.54 10.8 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) STALD PF18185.1 KFL60363.1 - 0.39 10.0 3.4 5.2 6.3 0.8 2.2 1 1 0 2 2 2 0 Sir2- and TIR-associating SLOG family GNAT_acetyltr_2 PF13718.6 KFL60363.1 - 7.2 5.9 7.2 2.9 7.2 0.2 2.5 2 0 0 2 2 2 0 GNAT acetyltransferase 2 DUF3824 PF12868.7 KFL60364.1 - 2.6e-14 54.1 25.6 2.6e-14 54.1 25.6 9.4 1 1 6 8 8 8 1 Domain of unknwon function (DUF3824) NDUF_B12 PF08122.12 KFL60364.1 - 0.0034 17.4 1.1 0.23 11.5 0.0 3.7 3 1 1 4 4 4 1 NADH-ubiquinone oxidoreductase B12 subunit family Transformer PF06495.11 KFL60364.1 - 0.0066 16.6 5.8 0.0066 16.6 5.8 7.2 3 3 3 7 7 7 1 Fruit fly transformer protein RskA PF10099.9 KFL60364.1 - 0.02 15.2 10.1 3 8.1 0.0 3.6 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF4473 PF14747.6 KFL60364.1 - 0.037 14.6 6.2 0.53 10.9 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) STALD PF18185.1 KFL60364.1 - 0.37 10.1 3.4 5.1 6.4 0.8 2.2 1 1 0 2 2 2 0 Sir2- and TIR-associating SLOG family GNAT_acetyltr_2 PF13718.6 KFL60364.1 - 6.7 6.0 7.2 2.8 7.3 0.2 2.5 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Transformer PF06495.11 KFL60365.1 - 0.007 16.5 5.9 0.007 16.5 5.9 6.5 3 3 1 5 5 5 1 Fruit fly transformer protein NDUF_B12 PF08122.12 KFL60365.1 - 0.016 15.2 1.7 0.22 11.6 0.0 3.3 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF4473 PF14747.6 KFL60365.1 - 0.035 14.7 6.2 0.49 11.0 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) RskA PF10099.9 KFL60365.1 - 0.049 13.9 9.8 5.1 7.4 0.6 3.5 2 1 1 3 3 3 0 Anti-sigma-K factor rskA STALD PF18185.1 KFL60365.1 - 0.32 10.3 3.4 4.7 6.5 0.8 2.2 1 1 0 2 2 2 0 Sir2- and TIR-associating SLOG family GNAT_acetyltr_2 PF13718.6 KFL60365.1 - 5.8 6.2 7.2 2.6 7.4 0.2 2.5 2 0 0 2 2 2 0 GNAT acetyltransferase 2 DUF3042 PF11240.8 KFL60365.1 - 9.9 6.3 10.2 0.99 9.5 1.0 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Transformer PF06495.11 KFL60366.1 - 0.0063 16.6 6.1 0.0063 16.6 6.1 6.7 3 3 4 7 7 7 1 Fruit fly transformer protein NDUF_B12 PF08122.12 KFL60366.1 - 0.01 15.9 1.6 0.18 11.8 0.0 3.4 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF4473 PF14747.6 KFL60366.1 - 0.014 16.0 5.5 0.42 11.2 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) RskA PF10099.9 KFL60366.1 - 0.04 14.2 10.2 5.2 7.3 0.8 3.5 2 1 1 3 3 3 0 Anti-sigma-K factor rskA STALD PF18185.1 KFL60366.1 - 0.26 10.6 3.6 4.1 6.7 0.8 2.2 1 1 1 2 2 2 0 Sir2- and TIR-associating SLOG family GNAT_acetyltr_2 PF13718.6 KFL60366.1 - 3.9 6.8 7.1 2.2 7.6 0.2 2.5 2 0 0 2 2 2 0 GNAT acetyltransferase 2 DUF3042 PF11240.8 KFL60366.1 - 7.1 6.7 10.2 0.86 9.7 1.0 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Ribosomal_L44 PF00935.19 KFL60367.1 - 5.7e-36 122.8 12.1 9e-36 122.2 12.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 KFL60367.1 - 0.74 10.2 4.7 0.15 12.4 1.2 1.6 2 0 0 2 2 2 0 Cathelicidin SR-25 PF10500.9 KFL60369.1 - 0.73 9.4 12.7 0.85 9.2 12.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 KFL60369.1 - 0.81 9.2 5.3 0.87 9.1 5.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MIT_LIKE_ACTX PF17556.2 KFL60370.1 - 0.14 12.8 0.1 0.24 12.0 0.1 1.3 1 0 0 1 1 1 0 MIT-like atracotoxin family KxDL PF10241.9 KFL60371.1 - 1.5e-23 82.9 1.0 1.8e-23 82.6 1.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein HATPase_c PF02518.26 KFL60373.1 - 2.6e-21 76.2 0.7 8.7e-21 74.5 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KFL60373.1 - 7.5e-16 57.9 0.0 2.4e-15 56.3 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KFL60373.1 - 1.3e-11 44.6 1.3 0.00047 20.4 0.2 3.9 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 KFL60373.1 - 3e-06 27.4 0.2 1.2e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KFL60373.1 - 0.00018 21.5 0.1 0.33 11.0 0.0 3.7 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.7 KFL60373.1 - 0.006 16.8 0.1 3.1 8.1 0.0 3.9 4 0 0 4 4 4 1 PAS domain Response_reg PF00072.24 KFL60373.1 - 0.096 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Response regulator receiver domain HATPase_c PF02518.26 KFL60374.1 - 2.5e-21 76.3 0.7 8.5e-21 74.6 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KFL60374.1 - 7.4e-16 58.0 0.0 2.4e-15 56.3 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KFL60374.1 - 1.3e-11 44.7 1.3 0.00046 20.4 0.2 3.8 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 KFL60374.1 - 3e-06 27.5 0.2 1.1e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KFL60374.1 - 0.00018 21.5 0.1 0.32 11.0 0.0 3.7 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.7 KFL60374.1 - 0.012 15.9 0.1 3 8.1 0.0 3.9 4 0 0 4 4 4 0 PAS domain ABC_membrane PF00664.23 KFL60377.1 - 5.2e-16 59.1 4.3 6.2e-16 58.9 4.3 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region Imm71 PF15602.6 KFL60377.1 - 0.11 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 71 Selenoprotein_S PF06936.11 KFL60377.1 - 0.2 11.5 0.0 0.38 10.5 0.0 1.5 1 1 1 2 2 2 0 Selenoprotein S (SelS) ABC_tran PF00005.27 KFL60378.1 - 1.1e-19 71.3 0.0 2.1e-19 70.4 0.0 1.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KFL60378.1 - 0.00018 21.0 0.1 0.00026 20.5 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ECH_2 PF16113.5 KFL60378.1 - 0.013 15.0 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase SbcCD_C PF13558.6 KFL60378.1 - 0.073 13.3 0.9 0.85 9.9 0.8 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 KFL60378.1 - 0.081 11.7 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Med1 PF10744.9 KFL60379.1 - 1.8e-133 445.6 0.0 3.4e-133 444.7 0.0 1.4 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 Gln-synt_C PF00120.24 KFL60379.1 - 1.1e-14 54.2 0.0 3.8e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFL60379.1 - 3.6e-12 45.9 0.0 7.7e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SelP_N PF04592.14 KFL60379.1 - 6.5 6.1 7.6 77 2.6 8.9 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region ORMDL PF04061.14 KFL60383.1 - 1.8e-58 196.2 3.4 2.1e-58 196.0 3.4 1.0 1 0 0 1 1 1 1 ORMDL family Doppel PF11466.8 KFL60385.1 - 1.4 8.7 5.4 1.3 8.8 3.0 2.0 2 0 0 2 2 2 0 Prion-like protein Doppel Glyco_tran_28_C PF04101.16 KFL60387.1 - 3.8e-18 66.0 0.1 1.8e-17 63.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain SNF2_N PF00176.23 KFL60388.1 - 9.6e-44 149.5 2.4 1.5e-43 148.9 2.4 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFL60388.1 - 9.6e-19 67.8 0.0 3e-18 66.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFL60388.1 - 1.3e-09 37.6 3.3 5e-09 35.7 3.3 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KFL60388.1 - 3.6e-05 23.8 0.0 0.00014 21.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1087 PF06465.13 KFL60388.1 - 0.0013 18.7 0.1 0.0044 17.0 0.1 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) DEAD_2 PF06733.15 KFL60388.1 - 0.0055 16.3 0.0 0.032 13.9 0.0 2.2 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 KFL60388.1 - 0.0075 16.1 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SnAC PF14619.6 KFL60388.1 - 0.061 13.9 1.0 0.18 12.4 1.0 1.8 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex zf-PHD-like PF15446.6 KFL60389.1 - 1.1e-64 217.1 11.9 2e-64 216.3 11.9 1.4 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD PF00628.29 KFL60389.1 - 4.7e-06 26.4 2.9 4.7e-06 26.4 2.9 4.0 2 2 0 2 2 2 2 PHD-finger Zf_RING PF16744.5 KFL60389.1 - 0.92 9.7 12.4 3.6 7.7 0.3 3.3 2 1 0 2 2 2 0 KIAA1045 RING finger C1_1 PF00130.22 KFL60389.1 - 1.4 8.9 12.3 3.5 7.6 1.1 3.9 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 KFL60389.1 - 1.7 8.9 11.2 0.22 11.7 2.8 2.5 1 1 1 2 2 2 0 PHD-zinc-finger like domain CxC5 PF18718.1 KFL60389.1 - 7.8 6.6 8.2 5.3 7.2 1.1 2.6 2 1 0 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases SNF2_N PF00176.23 KFL60390.1 - 1.7e-75 253.9 0.1 3.2e-75 253.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KFL60390.1 - 2.1e-43 147.0 0.9 2.1e-43 147.0 0.9 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KFL60390.1 - 7e-31 107.3 4.6 7e-31 107.3 4.6 3.8 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 KFL60390.1 - 6.2e-18 65.2 0.6 2.7e-17 63.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFL60390.1 - 8.2e-11 42.2 1.1 5.8e-10 39.4 0.0 3.0 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFL60390.1 - 1.4e-06 27.7 0.1 6.8e-06 25.4 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KFL60390.1 - 0.00028 20.6 0.0 0.0017 18.1 0.0 2.4 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 KFL60390.1 - 0.00054 19.8 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 KFL60390.1 - 0.0016 18.6 0.0 3.7 7.8 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF1086 PF06461.11 KFL60390.1 - 0.0036 17.1 0.1 0.0097 15.8 0.1 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) AAA_14 PF13173.6 KFL60390.1 - 0.023 14.7 0.4 0.12 12.4 0.0 2.5 2 0 0 2 2 1 0 AAA domain DEAD_2 PF06733.15 KFL60390.1 - 0.033 13.8 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 Ku_C PF03730.14 KFL60390.1 - 0.044 14.5 0.4 0.044 14.5 0.4 3.6 4 0 0 4 4 3 0 Ku70/Ku80 C-terminal arm Occludin_ELL PF07303.13 KFL60390.1 - 0.14 12.9 3.2 0.58 10.9 3.2 2.1 1 0 0 1 1 1 0 Occludin homology domain Aldedh PF00171.22 KFL60391.1 - 3.1e-78 263.4 0.0 3.5e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 KFL60392.1 - 9e-73 245.3 0.0 1.1e-72 245.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 KFL60393.1 - 2e-45 155.3 38.9 3.8e-36 124.8 24.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL60393.1 - 2.1e-06 26.9 12.1 2.1e-06 26.9 12.1 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TMEM100 PF16311.5 KFL60393.1 - 0.15 11.7 1.1 6.2 6.4 0.1 2.4 2 0 0 2 2 2 0 Transmembrane protein 100 MFS_1 PF07690.16 KFL60394.1 - 9.8e-42 143.1 34.6 2.4e-32 112.2 20.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL60394.1 - 5.9e-06 25.4 8.8 5.9e-06 25.4 8.8 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 KFL60394.1 - 0.0001 21.7 1.1 0.0001 21.7 1.1 2.8 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KFL60394.1 - 0.0014 17.0 7.1 0.088 11.1 2.3 2.6 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family PUCC PF03209.15 KFL60394.1 - 0.0036 16.3 0.1 0.0036 16.3 0.1 2.2 2 0 0 2 2 2 1 PUCC protein MFS_3 PF05977.13 KFL60394.1 - 0.024 13.0 10.4 0.0099 14.3 2.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_1 PF07690.16 KFL60395.1 - 1.5e-36 126.1 26.6 2.2e-36 125.5 26.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL60395.1 - 1.8e-06 27.1 12.4 1.8e-06 27.1 12.4 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KFL60395.1 - 0.00016 21.1 2.3 0.00016 21.1 2.3 1.9 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ICL PF00463.21 KFL60396.1 - 3.7e-21 75.2 1.1 3.9e-21 75.1 1.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family COX7a PF02238.15 KFL60396.1 - 0.045 14.1 0.7 0.053 13.9 0.2 1.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII ICL PF00463.21 KFL60397.1 - 4.8e-28 97.9 0.6 5.1e-28 97.8 0.6 1.1 1 0 0 1 1 1 1 Isocitrate lyase family ICL PF00463.21 KFL60398.1 - 8.5e-160 532.7 2.0 9.5e-160 532.6 2.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Forkhead PF00250.18 KFL60402.1 - 4.5e-34 116.6 1.6 9.5e-34 115.5 1.6 1.6 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KFL60402.1 - 5.3e-07 29.9 0.0 1.1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 KFL60402.1 - 0.0083 16.5 0.2 0.017 15.5 0.2 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Glyco_hydro_49N PF17433.2 KFL60406.1 - 0.089 12.4 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain PS_Dcarbxylase PF02666.15 KFL60408.1 - 2e-55 187.4 0.0 3e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KFL60408.1 - 3.3e-16 59.4 0.0 8.1e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_5 PF13202.6 KFL60408.1 - 0.0056 16.1 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KFL60408.1 - 0.026 14.0 0.0 0.073 12.7 0.0 1.8 1 0 0 1 1 1 0 EF hand AhpC-TSA_2 PF13911.6 KFL60408.1 - 0.076 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme C2 PF00168.30 KFL60409.1 - 8e-18 64.6 0.0 9.8e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 C2 domain MT0933_antitox PF14013.6 KFL60410.1 - 0.47 10.8 5.9 2.9 8.3 3.6 2.6 1 1 1 2 2 2 0 MT0933-like antitoxin protein MT0933_antitox PF14013.6 KFL60411.1 - 0.47 10.8 5.9 2.9 8.3 3.6 2.6 1 1 1 2 2 2 0 MT0933-like antitoxin protein GCS PF03074.16 KFL60413.1 - 1.7e-175 583.8 0.0 2e-175 583.5 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.11 KFL60413.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) DUF2811 PF10929.8 KFL60413.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) GCS PF03074.16 KFL60414.1 - 1.1e-175 584.3 0.0 1.3e-175 584.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.11 KFL60414.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) DUF2811 PF10929.8 KFL60414.1 - 0.091 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) GCS PF03074.16 KFL60415.1 - 1e-175 584.5 0.0 1.2e-175 584.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.11 KFL60415.1 - 0.0097 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1560) DUF2811 PF10929.8 KFL60415.1 - 0.085 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) GCS PF03074.16 KFL60416.1 - 1e-175 584.5 0.0 1.2e-175 584.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.11 KFL60416.1 - 0.0097 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1560) DUF2811 PF10929.8 KFL60416.1 - 0.085 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) GCS PF03074.16 KFL60417.1 - 1e-175 584.5 0.0 1.2e-175 584.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.11 KFL60417.1 - 0.0097 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1560) DUF2811 PF10929.8 KFL60417.1 - 0.085 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Fer4 PF00037.27 KFL60418.1 - 1e-13 50.4 16.5 4.8e-08 32.5 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KFL60418.1 - 1.1e-12 48.3 10.0 1.7e-12 47.7 10.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KFL60418.1 - 3.9e-08 33.3 10.0 6.2e-08 32.7 10.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KFL60418.1 - 9.7e-08 32.0 24.1 1.4e-05 25.2 13.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFL60418.1 - 3.8e-07 30.1 23.8 4.3e-06 26.7 12.6 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KFL60418.1 - 9.5e-07 28.6 17.1 0.00031 20.7 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KFL60418.1 - 9.8e-07 29.6 13.8 0.00043 21.2 2.5 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 KFL60418.1 - 3e-06 27.0 11.8 0.0077 16.3 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KFL60418.1 - 1.9e-05 24.8 13.0 0.00023 21.4 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KFL60418.1 - 0.00014 22.2 13.8 0.00096 19.6 12.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KFL60418.1 - 0.00067 20.2 11.9 0.03 14.9 12.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KFL60418.1 - 0.01 16.0 6.2 0.4 11.0 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 KFL60418.1 - 0.039 14.5 14.7 0.59 10.7 4.3 2.6 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KFL60418.1 - 0.064 13.5 9.1 0.91 9.7 1.7 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KFL60418.1 - 0.11 12.6 5.8 0.41 10.8 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 KFL60418.1 - 0.14 13.1 15.5 0.34 12.0 3.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KFL60418.1 - 0.51 11.2 11.7 1.8 9.4 1.6 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Rick_17kDa_Anti PF05433.15 KFL60419.1 - 3.9e-05 23.4 11.5 3.9e-05 23.4 11.5 2.9 3 1 0 3 3 3 1 Glycine zipper 2TM domain Rick_17kDa_Anti PF05433.15 KFL60420.1 - 3.9e-05 23.4 11.5 3.9e-05 23.4 11.5 2.9 3 1 0 3 3 3 1 Glycine zipper 2TM domain Mito_carr PF00153.27 KFL60422.1 - 2.7e-37 126.6 0.1 9.3e-19 67.2 0.0 2.4 3 0 0 3 3 3 2 Mitochondrial carrier protein Baculo_VP39 PF04501.12 KFL60423.1 - 0.03 13.8 1.0 0.061 12.8 1.2 1.4 1 1 1 2 2 2 0 Baculovirus major capsid protein VP39 TAF1D PF15333.6 KFL60424.1 - 1.7 8.3 8.8 2.2 8.0 8.8 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D RRM_1 PF00076.22 KFL60426.1 - 2.6e-09 36.8 0.0 4.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFL60426.1 - 0.0076 15.8 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Frag1 PF10277.9 KFL60427.1 - 6.9e-13 48.6 1.0 7.8e-13 48.5 1.0 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 KFL60428.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.22 KFL60430.1 - 1e-13 50.9 0.0 1.9e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup54 PF13874.6 KFL60430.1 - 0.021 15.0 0.2 0.039 14.1 0.2 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 RRM_1 PF00076.22 KFL60431.1 - 1e-13 50.9 0.0 1.9e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup54 PF13874.6 KFL60431.1 - 0.02 15.0 0.2 0.038 14.1 0.2 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 RRM_1 PF00076.22 KFL60432.1 - 9.9e-14 50.9 0.0 1.9e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup54 PF13874.6 KFL60432.1 - 0.02 15.0 0.2 0.037 14.1 0.2 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 RRM_1 PF00076.22 KFL60433.1 - 8.7e-14 51.1 0.0 1.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup54 PF13874.6 KFL60433.1 - 0.017 15.2 0.2 0.03 14.4 0.2 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 RRM_1 PF00076.22 KFL60434.1 - 8.6e-14 51.1 0.0 1.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup54 PF13874.6 KFL60434.1 - 0.016 15.3 0.2 0.029 14.5 0.2 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 RRM_1 PF00076.22 KFL60435.1 - 8.2e-14 51.2 0.0 1.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup54 PF13874.6 KFL60435.1 - 0.016 15.3 0.2 0.028 14.5 0.2 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Cpn60_TCP1 PF00118.24 KFL60436.1 - 1.2e-153 512.3 0.9 1.3e-153 512.1 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 KFL60437.1 - 3.4e-144 481.1 0.5 3.9e-144 480.9 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 KFL60438.1 - 3.3e-140 468.0 0.3 3.7e-140 467.8 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CLP1_P PF16575.5 KFL60439.1 - 2.2e-31 109.1 0.0 1e-30 106.9 0.0 2.0 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF3095 PF11294.8 KFL60439.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) AAA_33 PF13671.6 KFL60439.1 - 0.022 14.9 0.5 0.18 12.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KFL60439.1 - 0.044 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 KFL60439.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Septin PF00735.18 KFL60439.1 - 0.17 11.2 0.0 0.83 8.9 0.0 1.9 2 0 0 2 2 2 0 Septin Glyco_hydro_18 PF00704.28 KFL60441.1 - 2.2e-53 182.0 0.3 2.8e-53 181.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 KFL60441.1 - 0.028 13.9 0.1 0.039 13.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Glyco_transf_24 PF18404.1 KFL60444.1 - 1.6e-149 496.6 0.9 2.2e-149 496.2 0.9 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_15 PF18403.1 KFL60444.1 - 2.3e-43 148.6 0.0 3.8e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KFL60444.1 - 1.8e-41 140.6 0.0 4.1e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_14 PF18402.1 KFL60444.1 - 0.00029 20.9 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KFL60444.1 - 0.00048 19.8 0.0 0.00076 19.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF1416 PF07210.12 KFL60444.1 - 0.21 11.5 0.0 0.49 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Ribosomal_S14 PF00253.21 KFL60445.1 - 3.5e-18 65.1 0.4 9e-18 63.8 0.4 1.8 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e MGC-24 PF05283.11 KFL60446.1 - 1.1 9.7 5.0 1.5 9.3 5.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FHA PF00498.26 KFL60447.1 - 2.3e-16 59.9 0.0 4.4e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFL60447.1 - 0.0002 21.6 0.0 0.00058 20.1 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain MscS_porin PF12795.7 KFL60447.1 - 0.037 13.6 22.1 0.074 12.6 4.6 3.2 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Jnk-SapK_ap_N PF09744.9 KFL60447.1 - 0.28 11.4 15.2 0.48 10.6 4.3 2.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 T3SSipB PF16535.5 KFL60447.1 - 2.2 8.7 17.8 0.044 14.3 6.7 2.8 3 0 0 3 3 3 0 Type III cell invasion protein SipB GrpE PF01025.19 KFL60447.1 - 3.1 7.4 15.6 0.27 10.9 4.8 2.3 2 0 0 2 2 2 0 GrpE SelK_SelG PF10961.8 KFL60448.1 - 0.078 13.6 1.0 0.78 10.4 0.0 2.4 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Raptor_N PF14538.6 KFL60451.1 - 1.6e-65 219.6 0.0 2.6e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.22 KFL60451.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Caspase domain HEAT PF02985.22 KFL60451.1 - 0.004 17.3 1.0 0.75 10.2 0.0 3.6 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KFL60451.1 - 0.0069 16.7 0.0 0.029 14.8 0.0 2.1 1 0 0 1 1 1 1 HEAT repeats Atx10homo_assoc PF09759.9 KFL60451.1 - 0.0091 16.0 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Pkinase PF00069.25 KFL60452.1 - 4.8e-26 91.7 0.0 6e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60452.1 - 6.2e-14 51.9 0.0 8.2e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60452.1 - 4.6e-09 35.5 0.0 6.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL60452.1 - 0.00021 21.3 0.0 0.0015 18.5 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KFL60453.1 - 4.7e-26 91.7 0.0 5.9e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60453.1 - 6.1e-14 51.9 0.0 8e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60453.1 - 4.6e-09 35.6 0.0 6.3e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL60453.1 - 0.0002 21.3 0.0 0.0015 18.5 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KFL60454.1 - 2.7e-18 66.3 0.0 3.3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60454.1 - 2e-09 37.2 0.0 2.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60454.1 - 3.6e-09 35.9 0.0 5.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL60454.1 - 0.00071 19.6 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL60454.1 - 0.23 10.8 0.7 0.45 9.8 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFL60455.1 - 2.7e-18 66.3 0.0 3.3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60455.1 - 2e-09 37.2 0.0 2.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60455.1 - 3.6e-09 35.9 0.0 5.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL60455.1 - 0.00071 19.6 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL60455.1 - 0.23 10.8 0.7 0.45 9.8 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFL60456.1 - 2.7e-18 66.3 0.0 3.3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60456.1 - 2e-09 37.2 0.0 2.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60456.1 - 3.6e-09 35.9 0.0 5.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL60456.1 - 0.00071 19.6 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL60456.1 - 0.23 10.8 0.7 0.45 9.8 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFL60457.1 - 2e-18 66.7 0.0 2.5e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60457.1 - 1.5e-09 37.5 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60457.1 - 2.9e-09 36.2 0.0 4.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL60457.1 - 0.0006 19.8 0.0 0.00098 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL60457.1 - 0.18 11.2 0.6 0.36 10.2 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFL60458.1 - 2e-18 66.7 0.0 2.5e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60458.1 - 1.5e-09 37.5 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60458.1 - 2.9e-09 36.2 0.0 4.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL60458.1 - 0.0006 19.8 0.0 0.00098 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL60458.1 - 0.18 11.2 0.6 0.36 10.2 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFL60459.1 - 2e-18 66.7 0.0 2.5e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60459.1 - 1.5e-09 37.5 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60459.1 - 2.9e-09 36.2 0.0 4.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL60459.1 - 0.0006 19.8 0.0 0.00098 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL60459.1 - 0.18 11.2 0.6 0.36 10.2 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFL60460.1 - 2e-18 66.7 0.0 2.4e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60460.1 - 1.5e-09 37.6 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60460.1 - 2.8e-09 36.2 0.0 4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL60460.1 - 0.00059 19.8 0.0 0.00097 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL60460.1 - 0.17 11.2 0.6 0.35 10.2 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFL60461.1 - 2e-18 66.7 0.0 2.4e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60461.1 - 1.5e-09 37.6 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60461.1 - 2.8e-09 36.2 0.0 4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL60461.1 - 0.00059 19.8 0.0 0.00097 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL60461.1 - 0.17 11.2 0.6 0.35 10.2 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFL60462.1 - 2e-18 66.7 0.0 2.4e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60462.1 - 1.5e-09 37.6 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60462.1 - 2.8e-09 36.2 0.0 4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL60462.1 - 0.00059 19.8 0.0 0.00097 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL60462.1 - 0.17 11.2 0.6 0.35 10.2 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFL60463.1 - 2e-18 66.7 0.0 2.4e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60463.1 - 1.5e-09 37.6 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60463.1 - 2.8e-09 36.2 0.0 4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL60463.1 - 0.00059 19.8 0.0 0.00097 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL60463.1 - 0.17 11.2 0.6 0.35 10.2 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFL60464.1 - 2e-18 66.7 0.0 2.4e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60464.1 - 1.5e-09 37.6 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60464.1 - 2.8e-09 36.2 0.0 4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL60464.1 - 0.00059 19.8 0.0 0.00097 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL60464.1 - 0.17 11.2 0.6 0.35 10.2 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adaptin_N PF01602.20 KFL60465.1 - 7.8e-77 259.0 0.1 1e-76 258.6 0.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KFL60465.1 - 6.2e-60 201.7 1.4 1.3e-59 200.7 1.4 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KFL60465.1 - 2.2e-31 108.4 0.2 1.1e-30 106.2 0.0 2.2 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KFL60465.1 - 2.2e-17 63.2 0.7 9.9e-13 48.3 0.0 3.6 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KFL60465.1 - 2e-06 27.9 3.2 0.0011 19.0 0.1 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFL60465.1 - 0.00026 21.0 2.6 0.32 11.4 0.3 4.4 4 0 0 4 4 4 1 HEAT repeat Alpha_adaptin_C PF02296.16 KFL60465.1 - 0.0024 18.1 0.0 0.0064 16.7 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain HEAT_PBS PF03130.16 KFL60465.1 - 0.0029 18.1 1.9 1.8 9.4 0.1 4.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 KFL60465.1 - 0.046 14.2 1.0 0.17 12.4 0.4 2.3 2 0 0 2 2 2 0 HEAT-like repeat MRP-S35 PF10246.9 KFL60465.1 - 0.16 12.0 0.1 17 5.4 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 Adaptin_N PF01602.20 KFL60466.1 - 1.7e-70 238.1 0.0 1.4e-69 235.0 0.0 2.0 1 1 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KFL60466.1 - 5.6e-60 201.9 1.4 1.2e-59 200.9 1.4 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.6 KFL60466.1 - 1.9e-17 63.4 0.8 9.1e-13 48.4 0.0 3.5 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KFL60466.1 - 1.6e-06 28.3 3.1 0.001 19.1 0.1 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.5 KFL60466.1 - 4e-06 26.9 0.1 2.5e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KFL60466.1 - 0.00034 20.6 3.4 0.3 11.5 0.3 4.5 5 0 0 5 5 5 1 HEAT repeat HEAT_PBS PF03130.16 KFL60466.1 - 0.011 16.3 2.6 1.7 9.5 0.1 3.7 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 KFL60466.1 - 0.046 14.3 1.0 0.16 12.5 0.4 2.3 2 0 0 2 2 2 0 HEAT-like repeat MRP-S35 PF10246.9 KFL60466.1 - 0.14 12.2 0.1 16 5.6 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 Adaptin_N PF01602.20 KFL60467.1 - 6.2e-77 259.3 0.1 8.3e-77 258.9 0.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KFL60467.1 - 5.4e-60 201.9 1.4 1.1e-59 200.9 1.4 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.6 KFL60467.1 - 1.7e-17 63.6 0.8 8.7e-13 48.5 0.0 3.6 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KFL60467.1 - 1.3e-06 28.5 3.1 0.00098 19.2 0.1 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.5 KFL60467.1 - 3.8e-06 27.0 0.1 2.5e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KFL60467.1 - 0.00019 21.4 2.7 0.29 11.5 0.3 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_PBS PF03130.16 KFL60467.1 - 0.0023 18.4 1.9 1.6 9.6 0.1 4.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 KFL60467.1 - 0.04 14.4 0.9 0.15 12.6 0.4 2.3 2 0 0 2 2 2 0 HEAT-like repeat MRP-S35 PF10246.9 KFL60467.1 - 0.13 12.3 0.1 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 Ku_PK_bind PF08785.11 KFL60469.1 - 5.9e-39 132.9 0.3 8.9e-39 132.3 0.3 1.3 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 KFL60470.1 - 5.1e-29 101.4 0.0 7.8e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KFL60470.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KFL60470.1 - 0.0031 17.8 0.0 0.008 16.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Fungal_trans PF04082.18 KFL60471.1 - 8.3e-24 84.0 0.0 8.3e-24 84.0 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain DUF4834 PF16118.5 KFL60471.1 - 0.0016 19.4 5.4 0.0018 19.2 3.5 2.2 2 0 0 2 2 1 1 Domain of unknown function (DUF4834) Hid1 PF12722.7 KFL60471.1 - 0.0093 14.2 15.9 0.013 13.7 15.9 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein TFIIA PF03153.13 KFL60471.1 - 0.013 15.6 26.6 0.018 15.1 26.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 KFL60471.1 - 0.041 12.3 0.4 0.055 11.9 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spt20 PF12090.8 KFL60471.1 - 0.043 13.4 36.4 0.068 12.8 36.4 1.3 1 0 0 1 1 1 0 Spt20 family TERB2 PF15101.6 KFL60471.1 - 0.051 13.6 14.3 0.082 13.0 14.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Bud13 PF09736.9 KFL60471.1 - 0.17 12.3 14.4 0.23 11.9 13.3 1.7 2 0 0 2 2 1 0 Pre-mRNA-splicing factor of RES complex Roughex PF06020.11 KFL60471.1 - 0.23 10.5 14.7 0.36 9.9 14.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Macoilin PF09726.9 KFL60471.1 - 0.24 9.9 13.3 0.34 9.4 13.3 1.1 1 0 0 1 1 1 0 Macoilin family CobT PF06213.12 KFL60471.1 - 0.33 10.3 16.8 0.5 9.7 16.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Folliculin PF11704.8 KFL60471.1 - 0.73 9.7 9.4 1.4 8.8 9.4 1.5 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport MDM10 PF12519.8 KFL60471.1 - 0.89 8.3 9.5 1.3 7.8 9.5 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Band_3_cyto PF07565.13 KFL60471.1 - 0.95 9.2 10.5 1.5 8.6 10.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2722 PF10846.8 KFL60471.1 - 1.1 8.1 29.1 0.12 11.3 24.9 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2722) FTO_NTD PF12933.7 KFL60471.1 - 1.1 8.4 10.1 1.9 7.6 10.1 1.3 1 0 0 1 1 1 0 FTO catalytic domain Peroxin-13_N PF04088.13 KFL60471.1 - 1.2 9.5 5.4 2.9 8.2 5.4 1.6 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Ndc1_Nup PF09531.10 KFL60471.1 - 1.3 7.6 17.4 2.3 6.8 17.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF702 PF05142.12 KFL60471.1 - 1.6 9.2 12.5 3.1 8.3 12.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) PAT1 PF09770.9 KFL60471.1 - 1.6 6.9 26.6 2.2 6.4 26.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.17 KFL60471.1 - 1.8 8.7 13.1 0.16 12.1 6.9 2.2 2 1 0 2 2 2 0 DDHD domain NARP1 PF12569.8 KFL60471.1 - 1.8 7.4 11.8 2.6 6.8 11.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CPSF100_C PF13299.6 KFL60471.1 - 1.9 8.7 10.5 3.1 7.9 10.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SRP-alpha_N PF04086.13 KFL60471.1 - 1.9 8.3 17.1 2.8 7.8 17.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.12 KFL60471.1 - 2.1 8.1 13.0 3.1 7.5 13.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.10 KFL60471.1 - 3.3 7.8 8.2 20 5.2 8.9 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Coilin_N PF15862.5 KFL60471.1 - 3.5 7.4 16.4 6.5 6.6 16.4 1.4 1 0 0 1 1 1 0 Coilin N-terminus DUF966 PF06136.13 KFL60471.1 - 4 7.1 15.3 5.7 6.6 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4175 PF13779.6 KFL60471.1 - 4.2 5.1 24.9 6 4.7 24.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Plasmodium_Vir PF05795.11 KFL60471.1 - 4.6 6.6 11.1 7.9 5.8 11.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CLN3 PF02487.17 KFL60471.1 - 4.7 6.1 7.5 7.7 5.4 7.5 1.3 1 0 0 1 1 1 0 CLN3 protein CDC45 PF02724.14 KFL60471.1 - 4.8 5.3 12.9 6.5 4.9 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KFL60471.1 - 5.1 5.7 18.8 8.6 5.0 18.8 1.3 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 KFL60471.1 - 5.8 5.6 11.2 7.9 5.2 11.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Gti1_Pac2 PF09729.9 KFL60471.1 - 5.9 6.9 12.3 11 6.0 12.3 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family EMC3_TMCO1 PF01956.16 KFL60471.1 - 7.1 6.3 7.3 4.5 7.0 5.2 1.7 2 0 0 2 2 1 0 Integral membrane protein EMC3/TMCO1-like Neur_chan_memb PF02932.16 KFL60471.1 - 7.4 6.6 11.4 13 5.8 11.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Lin-8 PF03353.15 KFL60471.1 - 7.9 5.9 22.6 12 5.3 22.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Borrelia_P83 PF05262.11 KFL60471.1 - 9.8 4.5 15.3 14 4.0 15.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Fungal_trans PF04082.18 KFL60472.1 - 0.0018 17.3 0.0 0.0018 17.3 0.0 2.7 3 0 0 3 3 3 1 Fungal specific transcription factor domain TFIIA PF03153.13 KFL60472.1 - 0.0052 16.8 26.2 0.0073 16.3 26.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 KFL60472.1 - 0.0064 14.7 16.3 0.0085 14.3 16.3 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Spt20 PF12090.8 KFL60472.1 - 0.014 15.0 35.5 0.023 14.3 35.5 1.3 1 0 0 1 1 1 0 Spt20 family SID-1_RNA_chan PF13965.6 KFL60472.1 - 0.023 13.2 0.4 0.029 12.8 0.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TERB2 PF15101.6 KFL60472.1 - 0.033 14.2 14.5 0.054 13.6 14.5 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Roughex PF06020.11 KFL60472.1 - 0.099 11.7 14.2 0.15 11.1 14.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Macoilin PF09726.9 KFL60472.1 - 0.13 10.7 13.4 0.19 10.3 13.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF2722 PF10846.8 KFL60472.1 - 0.17 10.8 27.3 0.038 12.9 24.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) CobT PF06213.12 KFL60472.1 - 0.21 10.9 16.8 0.31 10.4 16.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Peroxin-13_N PF04088.13 KFL60472.1 - 0.22 11.8 4.1 0.66 10.3 4.1 1.8 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Ndc1_Nup PF09531.10 KFL60472.1 - 0.25 10.0 16.0 0.46 9.1 16.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 KFL60472.1 - 0.39 8.9 25.4 0.52 8.5 25.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.13 KFL60472.1 - 0.51 10.1 10.3 0.77 9.5 10.3 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF702 PF05142.12 KFL60472.1 - 0.52 10.8 11.8 1.1 9.8 11.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Serinc PF03348.15 KFL60472.1 - 0.52 9.2 3.0 0.43 9.5 1.7 1.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) DDHD PF02862.17 KFL60472.1 - 0.55 10.3 12.8 0.061 13.5 6.4 2.4 2 1 0 2 2 2 0 DDHD domain MDM10 PF12519.8 KFL60472.1 - 0.59 8.9 9.7 0.81 8.5 9.7 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FTO_NTD PF12933.7 KFL60472.1 - 0.66 9.2 10.2 1.2 8.4 10.2 1.3 1 0 0 1 1 1 0 FTO catalytic domain NARP1 PF12569.8 KFL60472.1 - 0.79 8.6 11.3 1.1 8.1 11.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cellulose_synt PF03552.14 KFL60472.1 - 0.92 7.9 2.9 1.2 7.5 2.9 1.1 1 0 0 1 1 1 0 Cellulose synthase SpoIIP PF07454.11 KFL60472.1 - 0.97 8.8 12.6 1.6 8.1 12.6 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SRP-alpha_N PF04086.13 KFL60472.1 - 1.3 8.9 17.3 1.8 8.4 17.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CPSF100_C PF13299.6 KFL60472.1 - 1.3 9.2 10.7 2.2 8.5 10.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 KFL60472.1 - 1.3 8.7 13.1 2 8.2 13.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KFL60472.1 - 1.7 7.3 18.0 2.9 6.5 18.0 1.3 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.6 KFL60472.1 - 1.9 6.3 24.3 2.5 5.9 24.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CLN3 PF02487.17 KFL60472.1 - 2.1 7.3 7.1 3.2 6.7 7.1 1.3 1 0 0 1 1 1 0 CLN3 protein Plasmodium_Vir PF05795.11 KFL60472.1 - 2.3 7.5 10.7 3.5 7.0 10.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF966 PF06136.13 KFL60472.1 - 2.4 7.8 15.4 3.3 7.3 15.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Peptidase_S49_N PF08496.10 KFL60472.1 - 2.7 8.1 8.9 14 5.7 9.1 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Coilin_N PF15862.5 KFL60472.1 - 2.9 7.7 16.7 5.3 6.9 16.7 1.4 1 0 0 1 1 1 0 Coilin N-terminus Gti1_Pac2 PF09729.9 KFL60472.1 - 3.2 7.8 12.3 6.4 6.8 12.3 1.6 1 0 0 1 1 1 0 Gti1/Pac2 family CDC45 PF02724.14 KFL60472.1 - 3.9 5.6 13.3 5.1 5.3 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 KFL60472.1 - 4.3 6.1 11.5 5.6 5.7 11.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter AIF_C PF14721.6 KFL60472.1 - 4.7 7.6 8.8 9.6 6.6 8.8 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Neur_chan_memb PF02932.16 KFL60472.1 - 4.8 7.2 11.4 7.4 6.6 11.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Lin-8 PF03353.15 KFL60472.1 - 5 6.6 22.8 7.4 6.0 22.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Zip PF02535.22 KFL60472.1 - 5.6 6.1 5.3 7.8 5.6 5.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.12 KFL60472.1 - 5.8 5.8 19.1 9.2 5.1 19.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EMC3_TMCO1 PF01956.16 KFL60472.1 - 6.2 6.5 8.0 1.6 8.4 4.6 1.8 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Borrelia_P83 PF05262.11 KFL60472.1 - 6.2 5.2 15.3 8.4 4.8 15.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_S64 PF08192.11 KFL60472.1 - 7.5 4.9 17.3 11 4.3 17.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Hydin_ADK PF17213.3 KFL60472.1 - 7.9 6.7 14.8 18 5.6 14.8 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain GREB1 PF15782.5 KFL60472.1 - 9.2 3.2 19.7 12 2.8 19.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4407 PF14362.6 KFL60472.1 - 9.7 5.4 13.2 17 4.7 13.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) tRNA-synt_2b PF00587.25 KFL60476.1 - 2.2e-30 106.0 0.0 9.9e-29 100.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.14 KFL60476.1 - 5e-13 48.9 0.0 9e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain HGTP_anticodon PF03129.20 KFL60476.1 - 2.6e-06 27.5 0.0 5.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KFL60476.1 - 0.0023 18.0 0.0 0.0068 16.4 0.0 1.8 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.14 KFL60477.1 - 1.7e-36 125.4 0.0 2e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.21 KFL60479.1 - 2.7e-10 40.9 0.5 1e-09 39.0 0.0 2.1 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UCH PF00443.29 KFL60481.1 - 9.2e-15 54.8 0.3 1.2e-14 54.5 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1935 PF09149.10 KFL60481.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) RPT PF13446.6 KFL60482.1 - 4e-48 161.2 1.6 5.7e-18 64.6 0.0 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 KFL60482.1 - 3.6e-24 85.7 0.3 3.2e-23 82.5 0.3 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFL60482.1 - 0.00025 20.7 0.1 0.00076 19.2 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Microvir_H PF04687.12 KFL60482.1 - 0.0045 16.4 0.2 0.0072 15.8 0.2 1.2 1 0 0 1 1 1 1 Microvirus H protein (pilot protein) Tim17 PF02466.19 KFL60483.1 - 1.8e-08 34.7 4.0 3.4e-08 33.8 4.0 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 KFL60483.1 - 0.16 12.0 0.8 1.1 9.3 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF543) PH PF00169.29 KFL60484.1 - 5.3e-05 23.7 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH PF00169.29 KFL60485.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 PH domain RRM_1 PF00076.22 KFL60486.1 - 2.3e-39 133.1 0.0 4.6e-15 55.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFL60486.1 - 0.00016 21.7 0.0 1.1 9.3 0.0 3.0 3 0 0 3 3 3 2 RNA binding motif RRM_5 PF13893.6 KFL60486.1 - 0.045 13.4 0.0 6 6.5 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFL60486.1 - 0.076 13.1 0.2 3.2 7.9 0.0 3.2 3 1 0 3 3 3 0 Limkain b1 RRM_1 PF00076.22 KFL60487.1 - 1.5e-22 79.2 0.0 3.7e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3343 PF11823.8 KFL60487.1 - 0.2 11.1 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) APG9 PF04109.16 KFL60490.1 - 7.8e-208 691.3 11.8 9.3e-208 691.1 11.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 SNF2_N PF00176.23 KFL60492.1 - 4e-35 121.2 0.0 5.6e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFL60492.1 - 2.6e-15 56.7 0.0 6.1e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFL60492.1 - 4.8e-05 22.7 0.0 0.0003 20.1 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KFL60492.1 - 0.018 15.0 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Mito_carr PF00153.27 KFL60493.1 - 1.1e-22 79.7 2.6 3.1e-13 49.4 0.2 2.6 2 1 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.27 KFL60494.1 - 1.2e-17 63.6 0.0 1.5e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein zf-C2H2_jaz PF12171.8 KFL60495.1 - 3.1e-10 40.1 4.3 3.1e-10 40.1 4.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFL60495.1 - 0.012 15.9 0.7 0.019 15.3 0.7 1.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KFL60495.1 - 0.035 14.1 1.2 0.035 14.1 1.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFL60495.1 - 0.058 14.3 0.7 0.058 14.3 0.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-SCNM1 PF15803.5 KFL60495.1 - 0.16 11.6 0.0 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 zf-H2C2_2 PF13465.6 KFL60495.1 - 0.22 12.0 2.2 0.5 10.9 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-met PF12874.7 KFL60495.1 - 2.4 8.7 6.4 0.68 10.4 1.7 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Glyco_transf_20 PF00982.21 KFL60496.1 - 4.8e-195 648.7 0.0 5.9e-195 648.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KFL60496.1 - 0.017 14.8 0.4 0.036 13.8 0.1 1.8 2 1 0 2 2 2 0 Starch synthase catalytic domain UL2 PF08196.11 KFL60497.1 - 0.095 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 UL2 protein Nucleos_tra2_C PF07662.13 KFL60498.1 - 1.7e-36 126.0 0.1 1.7e-36 126.0 0.1 3.7 4 1 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KFL60498.1 - 4.8e-23 81.5 4.7 4.8e-23 81.5 4.7 3.2 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus FA_desaturase PF00487.24 KFL60498.1 - 0.017 15.0 0.0 0.017 15.0 0.0 3.1 3 1 0 3 3 3 0 Fatty acid desaturase Nucleos_tra2_C PF07662.13 KFL60499.1 - 3.7e-73 245.8 1.0 3.7e-73 245.8 1.0 3.1 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KFL60499.1 - 3.9e-23 81.8 4.7 3.9e-23 81.8 4.7 3.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus UQ_con PF00179.26 KFL60500.1 - 1.3e-40 138.3 0.0 1.6e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFL60500.1 - 7.8e-05 22.9 0.0 0.00012 22.4 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 KFL60500.1 - 0.0073 16.2 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 KFL60500.1 - 0.037 13.7 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 KFL60500.1 - 0.065 12.9 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 KFL60501.1 - 8.5e-49 164.8 0.0 9.5e-49 164.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFL60501.1 - 0.00017 21.9 0.0 0.00019 21.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFL60501.1 - 0.0023 17.6 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFL60501.1 - 0.0028 17.5 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 UEV domain Sec63 PF02889.16 KFL60503.1 - 4e-30 104.8 0.0 6.5e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KFL60503.1 - 8.1e-28 97.4 0.2 2.6e-27 95.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KFL60503.1 - 1.9e-14 54.1 0.0 3.6e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFL60503.1 - 1.6e-08 34.9 0.0 8e-08 32.6 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KFL60503.1 - 2.7e-05 24.6 0.0 0.00018 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFL60503.1 - 0.00066 20.0 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 KFL60503.1 - 0.0019 17.9 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_30 PF13604.6 KFL60503.1 - 0.0042 16.8 0.0 0.0098 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KFL60503.1 - 0.0079 16.1 0.1 0.49 10.2 0.0 2.5 2 0 0 2 2 2 1 Helicase AAA PF00004.29 KFL60503.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IBR PF01485.21 KFL60504.1 - 3.2e-23 81.7 49.4 1.1e-12 48.0 6.4 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain UN_NPL4 PF11543.8 KFL60504.1 - 0.00044 20.7 0.0 0.00078 19.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_2 PF13639.6 KFL60504.1 - 0.00088 19.6 8.7 0.00088 19.6 8.7 3.9 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 KFL60504.1 - 0.0015 18.3 5.4 0.0015 18.3 5.4 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFL60504.1 - 0.0063 16.3 5.6 0.0063 16.3 5.6 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFL60504.1 - 0.012 15.5 9.6 0.012 15.5 9.6 3.6 3 1 0 3 3 3 0 zinc-RING finger domain IBR PF01485.21 KFL60505.1 - 2.9e-23 81.9 49.4 1.1e-12 48.0 6.4 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain UN_NPL4 PF11543.8 KFL60505.1 - 0.00043 20.7 0.0 0.00076 19.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_2 PF13639.6 KFL60505.1 - 0.00085 19.6 8.7 0.00085 19.6 8.7 3.9 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 KFL60505.1 - 0.0015 18.4 5.4 0.0015 18.4 5.4 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFL60505.1 - 0.0061 16.4 5.6 0.0061 16.4 5.6 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFL60505.1 - 0.012 15.6 9.6 0.012 15.6 9.6 3.6 3 1 0 3 3 3 0 zinc-RING finger domain IBR PF01485.21 KFL60506.1 - 2.7e-23 81.9 49.4 1e-12 48.1 6.4 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain UN_NPL4 PF11543.8 KFL60506.1 - 0.00042 20.8 0.0 0.00074 19.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_2 PF13639.6 KFL60506.1 - 0.00084 19.6 8.7 0.00084 19.6 8.7 3.9 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 KFL60506.1 - 0.0015 18.4 5.4 0.0015 18.4 5.4 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFL60506.1 - 0.006 16.4 5.6 0.006 16.4 5.6 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFL60506.1 - 0.012 15.6 9.6 0.012 15.6 9.6 3.6 3 1 0 3 3 3 0 zinc-RING finger domain Redoxin PF08534.10 KFL60507.1 - 1.6e-28 99.2 0.0 2.2e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFL60507.1 - 5.4e-07 29.6 0.0 9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFL60508.1 - 1.2e-30 106.2 0.0 1.4e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFL60508.1 - 4.8e-07 29.7 0.0 6.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Glucan_synthase PF02364.15 KFL60510.1 - 0 1370.6 0.0 0 1370.1 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KFL60510.1 - 2.5e-43 147.5 0.2 6.6e-43 146.1 0.2 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glucan_synthase PF02364.15 KFL60511.1 - 0 1370.6 0.0 0 1370.1 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KFL60511.1 - 2.5e-43 147.5 0.2 6.6e-43 146.1 0.2 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 AIM24 PF01987.17 KFL60512.1 - 2.3e-42 145.1 0.1 3e-42 144.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Pkinase PF00069.25 KFL60513.1 - 1.3e-67 228.0 0.0 1.5e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60513.1 - 8.5e-32 110.5 0.0 1.1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFL60513.1 - 0.00054 19.4 0.2 0.0009 18.7 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFL60513.1 - 0.002 17.1 0.1 0.0031 16.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFL60513.1 - 0.0098 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFL60513.1 - 0.029 14.3 0.2 0.086 12.7 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFL60513.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 S_100 PF01023.19 KFL60513.1 - 0.15 11.8 0.8 0.45 10.3 0.8 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Pkinase PF00069.25 KFL60514.1 - 3.6e-58 197.0 0.1 4.7e-58 196.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60514.1 - 2.2e-25 89.4 0.1 3e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFL60514.1 - 0.00065 19.1 0.2 0.0012 18.3 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFL60514.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFL60514.1 - 0.0094 14.9 0.2 0.023 13.6 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFL60514.1 - 0.023 14.6 0.2 0.05 13.5 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFL60514.1 - 0.064 12.3 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 KFL60515.1 - 3.3e-58 197.1 0.1 4.4e-58 196.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60515.1 - 2.1e-25 89.5 0.1 2.9e-25 89.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFL60515.1 - 0.00068 19.1 0.2 0.0011 18.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFL60515.1 - 0.0073 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFL60515.1 - 0.0092 15.0 0.2 0.022 13.7 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFL60515.1 - 0.023 14.6 0.2 0.048 13.6 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFL60515.1 - 0.062 12.3 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 S_100 PF01023.19 KFL60515.1 - 0.3 10.8 2.2 0.36 10.6 0.8 1.8 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain Pkinase PF00069.25 KFL60516.1 - 2.5e-50 171.3 0.0 3.1e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60516.1 - 6.3e-20 71.5 0.0 8.7e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFL60516.1 - 0.0026 17.2 0.3 0.0041 16.5 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFL60516.1 - 0.0097 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFL60516.1 - 0.03 14.2 0.1 0.049 13.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFL60516.1 - 0.037 13.0 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFL60516.1 - 0.074 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 S_100 PF01023.19 KFL60516.1 - 0.77 9.5 2.6 0.88 9.3 1.1 1.8 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain Pkinase PF00069.25 KFL60517.1 - 2.3e-50 171.4 0.0 2.9e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60517.1 - 6e-20 71.6 0.0 8.2e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFL60517.1 - 0.0027 17.1 0.3 0.004 16.5 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFL60517.1 - 0.0093 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFL60517.1 - 0.03 14.2 0.1 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFL60517.1 - 0.037 13.0 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFL60517.1 - 0.071 12.1 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 S_100 PF01023.19 KFL60517.1 - 0.23 11.2 2.0 0.31 10.8 0.8 1.8 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain Epimerase PF01370.21 KFL60519.1 - 7.1e-09 35.5 0.0 8.8e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFL60519.1 - 1.9e-07 30.9 0.0 2.6e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFL60519.1 - 2.9e-06 27.3 0.0 5.3e-06 26.5 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFL60519.1 - 1.5e-05 24.5 0.0 1.9e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KFL60519.1 - 2.2e-05 24.0 0.0 3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KFL60519.1 - 4.6e-05 22.6 0.0 6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KFL60519.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 KFL60519.1 - 0.0021 17.2 0.1 0.0029 16.8 0.1 1.2 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KFL60519.1 - 0.04 13.0 0.0 0.051 12.7 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain DDE_Tnp_1_3 PF13612.6 KFL60519.1 - 0.047 13.7 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain THF_DHG_CYH_C PF02882.19 KFL60519.1 - 0.054 12.8 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain A_deaminase PF00962.22 KFL60520.1 - 5.3e-21 75.3 0.0 6.6e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase ATG2_CAD PF13329.6 KFL60521.1 - 7.3e-46 155.7 0.1 1.7e-45 154.6 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KFL60521.1 - 1.3e-25 89.5 0.5 4.1e-25 88.0 0.1 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 KFL60521.1 - 0.0021 17.9 0.1 0.0084 15.9 0.1 2.0 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal SDH_sah PF01972.16 KFL60523.1 - 0.056 12.4 0.1 0.067 12.2 0.1 1.1 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Trp_repressor PF01371.19 KFL60523.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Trp repressor protein CN_hydrolase PF00795.22 KFL60524.1 - 4.6e-56 190.0 0.0 5.4e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L31e PF01198.19 KFL60525.1 - 3e-31 107.5 0.2 4e-31 107.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 KFL60525.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein SCP2 PF02036.17 KFL60526.1 - 9.1e-25 87.1 0.1 1e-24 86.9 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KFL60526.1 - 3.5e-05 24.1 0.0 4.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KFL60526.1 - 0.0031 17.9 0.0 0.0041 17.5 0.0 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain 7TMR-DISM_7TM PF07695.11 KFL60527.1 - 0.57 10.0 9.2 1.7 8.5 9.2 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling 7TMR-DISM_7TM PF07695.11 KFL60528.1 - 0.014 15.3 2.6 0.018 15.0 2.6 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling NRDE-2 PF08424.10 KFL60529.1 - 6.2e-94 314.7 0.5 2.5e-93 312.7 0.0 1.9 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 KFL60529.1 - 0.052 14.2 0.1 0.14 12.8 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFL60529.1 - 0.74 9.8 3.8 3.6 7.6 0.3 3.2 3 1 0 4 4 4 0 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 KFL60529.1 - 2 9.0 5.9 0.28 11.7 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat U3snoRNP10 PF12397.8 KFL60530.1 - 8.2e-26 90.6 9.5 1e-24 87.1 0.5 3.8 4 0 0 4 4 4 2 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 KFL60530.1 - 0.00027 21.3 0.9 0.82 10.1 0.0 4.9 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KFL60530.1 - 0.0019 18.6 2.0 3.1 8.4 0.0 4.8 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.22 KFL60530.1 - 0.012 15.8 4.3 0.61 10.5 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat IF-2 PF11987.8 KFL60530.1 - 0.051 13.7 0.1 0.19 11.8 0.1 2.0 1 0 0 1 1 1 0 Translation-initiation factor 2 Cnd1 PF12717.7 KFL60530.1 - 0.1 12.6 4.9 1.5 8.9 0.5 3.7 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Cas_Csn2 PF09711.10 KFL60530.1 - 0.12 12.0 2.6 0.26 11.0 2.6 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) Adaptin_N PF01602.20 KFL60530.1 - 0.25 9.9 10.9 0.68 8.4 0.6 3.9 3 2 1 4 4 4 0 Adaptin N terminal region BP28CT PF08146.12 KFL60531.1 - 1.6e-43 148.3 0.1 2.4e-42 144.5 0.3 2.5 2 1 0 2 2 2 1 BP28CT (NUC211) domain HEAT_2 PF13646.6 KFL60531.1 - 0.032 14.6 0.6 23 5.4 0.0 3.9 3 1 0 3 3 3 0 HEAT repeats DUF1098 PF06497.11 KFL60531.1 - 0.15 12.6 0.7 0.56 10.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) MMS1_N PF10433.9 KFL60532.1 - 3.6e-116 388.7 0.0 5.2e-116 388.2 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFL60532.1 - 8.1e-102 340.8 0.0 4.9e-101 338.3 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KFL60532.1 - 0.079 13.3 0.0 1.9 8.9 0.0 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L18p PF00861.22 KFL60533.1 - 0.067 13.6 0.0 0.089 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast PUF PF00806.19 KFL60534.1 - 6.8e-57 186.1 6.4 1.6e-07 30.6 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Rap_GAP PF02145.15 KFL60535.1 - 1.5e-47 161.6 0.1 2.2e-47 161.0 0.1 1.3 1 0 0 1 1 1 1 Rap/ran-GAP DUF3384 PF11864.8 KFL60536.1 - 4.2e-89 299.7 0.6 1.2e-88 298.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Tuberin PF03542.16 KFL60536.1 - 4.1e-37 128.1 0.0 5.5e-33 114.5 0.0 2.2 2 0 0 2 2 2 2 Tuberin Wzy_C PF04932.15 KFL60537.1 - 0.0066 16.1 0.0 0.018 14.7 0.1 1.6 2 0 0 2 2 2 1 O-Antigen ligase CLPTM1 PF05602.12 KFL60539.1 - 2.2e-149 498.1 0.7 2.5e-149 498.0 0.7 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) MtN3_slv PF03083.16 KFL60539.1 - 0.023 14.8 0.6 0.096 12.7 0.3 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange SyrA PF11089.8 KFL60539.1 - 0.33 11.1 2.4 13 5.9 0.6 2.6 2 0 0 2 2 2 0 Exopolysaccharide production repressor Catalase PF00199.19 KFL60540.1 - 4.8e-105 351.8 0.0 6.6e-105 351.4 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFL60540.1 - 1.4e-16 60.4 0.0 2.5e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KFL60540.1 - 5.9e-08 32.5 0.1 9.9e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KFL60540.1 - 0.00045 20.1 0.0 0.00096 19.0 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family Citrate_synt PF00285.21 KFL60543.1 - 5.6e-77 259.3 0.0 8.5e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Citrate_synt PF00285.21 KFL60544.1 - 1.6e-97 326.8 0.0 1.8e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ABC_tran PF00005.27 KFL60545.1 - 1e-30 107.0 0.1 2.9e-15 57.0 0.0 3.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFL60545.1 - 1.1e-13 51.7 0.5 2.3e-05 24.4 0.0 3.5 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFL60545.1 - 1.4e-08 34.5 0.8 0.0012 18.3 0.0 3.6 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFL60545.1 - 1.6e-08 34.6 0.3 0.0096 16.0 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFL60545.1 - 4.6e-07 29.9 0.1 0.02 14.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KFL60545.1 - 7.5e-07 29.8 1.9 0.0076 16.8 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 KFL60545.1 - 1.4e-05 24.7 3.1 0.09 12.5 1.3 3.0 2 1 1 3 3 3 2 P-loop containing region of AAA domain DUF87 PF01935.17 KFL60545.1 - 0.00019 21.6 1.2 0.048 13.7 0.1 3.0 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_28 PF13521.6 KFL60545.1 - 0.00022 21.5 0.1 0.016 15.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KFL60545.1 - 0.00029 20.8 0.8 0.19 11.6 0.0 2.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KFL60545.1 - 0.00029 21.1 0.0 0.71 10.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFL60545.1 - 0.00043 20.1 0.1 0.77 9.4 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KFL60545.1 - 0.00047 20.7 0.5 6.4 7.3 0.0 3.8 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.22 KFL60545.1 - 0.00085 19.7 0.1 1.4 9.3 0.0 2.9 2 0 0 2 2 2 1 RNA helicase Roc PF08477.13 KFL60545.1 - 0.0075 16.5 0.0 6.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KFL60545.1 - 0.011 15.5 0.5 1.5 8.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KFL60545.1 - 0.012 14.7 0.4 3 6.7 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KFL60545.1 - 0.013 15.3 3.0 0.95 9.1 0.2 3.3 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KFL60545.1 - 0.014 14.6 0.4 0.71 9.0 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.25 KFL60545.1 - 0.015 15.0 0.1 3.8 7.1 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 KFL60545.1 - 0.016 15.0 0.1 0.69 9.7 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 KFL60545.1 - 0.025 15.0 0.3 2.3 8.7 0.0 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFL60545.1 - 0.03 14.5 0.0 8.9 6.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain HEAT PF02985.22 KFL60545.1 - 0.035 14.3 0.5 84 3.8 0.0 4.6 5 0 0 5 5 4 0 HEAT repeat ALF PF03752.13 KFL60545.1 - 0.04 13.9 2.7 0.2 11.7 0.6 2.6 2 0 0 2 2 2 0 Short repeats of unknown function AAA_13 PF13166.6 KFL60545.1 - 0.043 12.5 0.0 4.8 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KFL60545.1 - 0.047 13.6 0.0 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MukB PF04310.12 KFL60545.1 - 0.06 13.1 0.3 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 MukB N-terminal DUF3584 PF12128.8 KFL60545.1 - 0.065 10.7 2.9 0.91 6.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Septin PF00735.18 KFL60545.1 - 0.085 12.1 0.1 13 4.9 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 KFL60545.1 - 0.089 13.2 0.4 31 4.9 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain DUF815 PF05673.13 KFL60545.1 - 0.11 11.7 0.5 4.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PIN7 PF18475.1 KFL60545.1 - 0.15 12.7 0.0 0.38 11.4 0.0 1.6 1 0 0 1 1 1 0 PIN domain Dynamin_N PF00350.23 KFL60545.1 - 0.2 11.7 0.9 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Dynamin family NTPase_1 PF03266.15 KFL60545.1 - 0.36 10.7 4.4 8.5 6.3 0.0 3.6 4 0 0 4 4 3 0 NTPase AA_permease_2 PF13520.6 KFL60546.1 - 4.9e-29 101.4 19.1 6e-29 101.1 19.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFL60546.1 - 1.4e-14 53.5 13.6 1.8e-14 53.3 13.6 1.1 1 0 0 1 1 1 1 Amino acid permease LapA_dom PF06305.11 KFL60546.1 - 0.065 13.1 2.4 0.23 11.3 0.1 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF4668 PF15701.5 KFL60546.1 - 0.14 12.0 4.7 0.19 11.6 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4668) DUF3043 PF11241.8 KFL60546.1 - 1.3 9.0 3.8 0.78 9.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) L51_S25_CI-B8 PF05047.16 KFL60547.1 - 5.2e-13 48.7 0.0 6.8e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Glyco_hydro_36 PF17167.4 KFL60547.1 - 0.2 10.3 0.0 0.24 10.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain DUF3237 PF11578.8 KFL60550.1 - 3.5e-33 114.6 0.0 4.5e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Spt20 PF12090.8 KFL60551.1 - 0.0004 20.1 13.9 0.00042 20.0 13.9 1.2 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 KFL60551.1 - 0.0014 17.7 9.7 0.0014 17.6 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 KFL60551.1 - 0.0046 17.6 9.1 0.0055 17.4 9.1 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SARAF PF06682.12 KFL60551.1 - 0.018 14.7 9.7 0.019 14.6 9.7 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis zf-BED PF02892.15 KFL60551.1 - 0.019 15.0 0.5 0.028 14.4 0.5 1.3 1 0 0 1 1 1 0 BED zinc finger TFIIA PF03153.13 KFL60551.1 - 0.026 14.5 17.4 0.024 14.7 17.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 KFL60551.1 - 0.095 11.0 10.4 0.11 10.7 10.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 KFL60551.1 - 0.2 10.4 1.6 0.18 10.5 1.6 1.1 1 0 0 1 1 1 0 Presenilin CCDC53 PF10152.9 KFL60551.1 - 0.2 12.1 5.4 0.23 11.9 5.4 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex eIF-3_zeta PF05091.12 KFL60551.1 - 0.66 8.9 6.2 0.73 8.7 6.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2464 PF10240.9 KFL60551.1 - 0.71 9.4 4.6 0.95 9.0 4.6 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 Suf PF05843.14 KFL60551.1 - 0.94 9.4 7.8 1.1 9.2 7.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 KFL60551.1 - 1.1 7.8 3.9 1.2 7.8 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Roughex PF06020.11 KFL60551.1 - 1.9 7.5 8.1 2.1 7.3 8.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein E_Pc_C PF06752.12 KFL60551.1 - 2.1 8.4 15.2 2.8 8.0 15.2 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus DUF4175 PF13779.6 KFL60551.1 - 2.3 6.0 17.1 2.4 6.0 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) UPF0560 PF10577.9 KFL60551.1 - 3.7 5.9 9.9 4.2 5.8 9.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3464 PF11947.8 KFL60551.1 - 5 6.9 5.9 6.9 6.4 5.9 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 ApbA PF02558.16 KFL60552.1 - 3.4e-25 88.4 0.0 5.6e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KFL60552.1 - 6.7e-24 84.5 0.0 1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA_C PF08546.11 KFL60553.1 - 2.3e-22 79.5 0.0 3.6e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA_C PF08546.11 KFL60554.1 - 2.3e-22 79.5 0.0 3.6e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA_C PF08546.11 KFL60555.1 - 2.3e-22 79.5 0.0 3.6e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Myticin-prepro PF10690.9 KFL60556.1 - 0.068 13.4 0.5 0.12 12.7 0.5 1.4 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Homeodomain PF00046.29 KFL60560.1 - 5.2e-14 51.8 1.2 1.2e-13 50.7 1.2 1.7 1 0 0 1 1 1 1 Homeodomain Pcc1 PF09341.10 KFL60561.1 - 1.5e-32 111.6 1.7 2e-32 111.2 1.7 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 CFEM PF05730.11 KFL60564.1 - 2.2e-05 24.4 6.3 4.5e-05 23.5 6.3 1.4 1 0 0 1 1 1 1 CFEM domain EphA2_TM PF14575.6 KFL60564.1 - 0.19 12.6 0.0 0.64 10.9 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Spermine_synth PF01564.17 KFL60566.1 - 5.2e-55 185.8 0.0 7.6e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KFL60566.1 - 3.5e-23 81.2 0.1 6.3e-23 80.4 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KFL60566.1 - 0.00016 22.3 0.0 0.00029 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFL60566.1 - 0.0014 19.3 0.2 0.0067 17.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFL60566.1 - 0.0024 17.7 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 KFL60566.1 - 0.0086 15.3 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_30 PF05430.11 KFL60566.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 KFL60566.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 KFL60566.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Spermine_synth PF01564.17 KFL60567.1 - 4.6e-67 225.1 0.0 5.8e-67 224.8 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 KFL60567.1 - 6.7e-05 23.5 0.0 0.00013 22.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFL60567.1 - 0.0003 20.6 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFL60567.1 - 0.0016 19.2 0.0 0.0034 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 KFL60567.1 - 0.0041 16.4 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain MTS PF05175.14 KFL60567.1 - 0.072 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 KFL60567.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Transketolase_N PF00456.21 KFL60568.1 - 1.3e-151 504.3 0.0 1.7e-151 503.9 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFL60568.1 - 6e-46 156.4 0.0 9.4e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFL60568.1 - 1.1e-10 41.5 0.0 2.4e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KFL60568.1 - 2.5e-05 23.7 0.0 6.9e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 KFL60568.1 - 0.11 11.7 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Mur_ligase_C PF02875.21 KFL60568.1 - 0.12 12.6 0.0 0.45 10.8 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain TPP_enzyme_C PF02775.21 KFL60568.1 - 0.37 10.6 7.3 0.086 12.6 1.1 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 KFL60569.1 - 1e-138 461.9 0.0 1.4e-138 461.5 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFL60569.1 - 5.6e-46 156.4 0.0 9e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFL60569.1 - 3.3e-12 46.4 0.0 7.1e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KFL60569.1 - 3e-05 23.4 0.0 8.6e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 KFL60569.1 - 0.11 11.8 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase Mur_ligase_C PF02875.21 KFL60569.1 - 0.12 12.6 0.0 0.44 10.8 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain TPP_enzyme_C PF02775.21 KFL60569.1 - 0.36 10.6 7.4 0.085 12.6 1.1 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 KFL60570.1 - 9.9e-139 461.9 0.0 1.3e-138 461.6 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFL60570.1 - 5.4e-46 156.5 0.0 8.5e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFL60570.1 - 1e-10 41.6 0.0 2.3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KFL60570.1 - 2.8e-05 23.5 0.0 8.2e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 KFL60570.1 - 0.1 11.8 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase Mur_ligase_C PF02875.21 KFL60570.1 - 0.11 12.7 0.0 0.43 10.9 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain TPP_enzyme_C PF02775.21 KFL60570.1 - 0.34 10.7 7.4 0.082 12.7 1.1 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 KFL60571.1 - 7e-110 367.1 0.0 9.3e-110 366.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFL60571.1 - 4.8e-46 156.7 0.0 7.6e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFL60571.1 - 2.8e-12 46.6 0.0 6.2e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KFL60571.1 - 4.9e-05 22.7 0.0 0.00014 21.2 0.0 1.7 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 KFL60571.1 - 0.099 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Mur_ligase_C PF02875.21 KFL60571.1 - 0.11 12.8 0.0 0.4 11.0 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain TPP_enzyme_C PF02775.21 KFL60571.1 - 0.34 10.7 7.6 0.078 12.8 1.2 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 KFL60572.1 - 6.6e-110 367.2 0.0 8.7e-110 366.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFL60572.1 - 4.6e-46 156.7 0.0 7.2e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFL60572.1 - 8.7e-11 41.8 0.0 2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KFL60572.1 - 4.6e-05 22.8 0.0 0.00013 21.3 0.0 1.7 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 KFL60572.1 - 0.094 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Mur_ligase_C PF02875.21 KFL60572.1 - 0.1 12.9 0.0 0.38 11.0 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain TPP_enzyme_C PF02775.21 KFL60572.1 - 0.31 10.8 7.6 0.074 12.8 1.2 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 KFL60573.1 - 5.5e-70 236.0 0.0 7.4e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFL60573.1 - 3.8e-46 157.0 0.0 5.9e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFL60573.1 - 2.6e-12 46.7 0.0 5e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Mur_ligase_C PF02875.21 KFL60573.1 - 0.085 13.1 0.0 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Transketolase_N PF00456.21 KFL60574.1 - 5.1e-70 236.1 0.0 7e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFL60574.1 - 3.7e-46 157.0 0.0 5.5e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFL60574.1 - 8.1e-11 41.9 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Mur_ligase_C PF02875.21 KFL60574.1 - 0.079 13.2 0.0 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Fungal_trans PF04082.18 KFL60575.1 - 6.7e-23 81.1 0.1 1.3e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DLH PF01738.18 KFL60577.1 - 5.4e-15 55.5 0.0 8.1e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KFL60577.1 - 0.08 12.6 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 KFL60578.1 - 6.5e-11 42.2 0.0 8.8e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KFL60578.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 KFL60579.1 - 6.5e-11 42.2 0.0 8.8e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KFL60579.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 KFL60580.1 - 6.5e-11 42.2 0.0 8.8e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KFL60580.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF423 PF04241.15 KFL60584.1 - 0.015 15.5 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF423) LapA_dom PF06305.11 KFL60584.1 - 0.017 15.0 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FAM176 PF14851.6 KFL60584.1 - 0.021 14.5 0.2 0.025 14.2 0.2 1.2 1 0 0 1 1 1 0 FAM176 family DUF2269 PF10027.9 KFL60584.1 - 0.057 13.5 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Ctr PF04145.15 KFL60585.1 - 2.2e-40 138.7 0.2 2.7e-40 138.4 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Ctr PF04145.15 KFL60586.1 - 4.2e-30 105.3 0.0 4.9e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Ctr PF04145.15 KFL60587.1 - 4.2e-30 105.3 0.0 4.9e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Metallophos PF00149.28 KFL60588.1 - 6.4e-28 98.7 0.0 8.6e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KFL60588.1 - 0.0016 18.1 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Aldedh PF00171.22 KFL60589.1 - 2.1e-179 596.9 0.2 2.4e-179 596.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFL60589.1 - 0.14 11.6 0.0 17 4.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Aldedh PF00171.22 KFL60590.1 - 2.3e-165 550.6 0.2 2.6e-165 550.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MAS20 PF02064.15 KFL60593.1 - 3.5e-26 91.8 0.2 4e-26 91.6 0.2 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor MAS20 PF02064.15 KFL60594.1 - 3.4e-27 95.1 0.2 4.1e-27 94.8 0.2 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor RRM_1 PF00076.22 KFL60595.1 - 5.1e-14 51.8 0.0 8.6e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFL60595.1 - 8e-06 25.6 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif FoP_duplication PF13865.6 KFL60595.1 - 7.1e-05 23.3 1.0 7.1e-05 23.3 1.0 2.8 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_7 PF16367.5 KFL60595.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif DUF3997 PF13162.6 KFL60596.1 - 0.17 12.2 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) Erythro-docking PF09277.11 KFL60597.1 - 0.0085 16.0 1.4 0.016 15.1 0.2 1.9 2 0 0 2 2 2 1 Erythronolide synthase, docking SipA_VBS PF17985.1 KFL60597.1 - 0.45 10.5 0.0 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 SipA vinculin binding site ABC_tran PF00005.27 KFL60598.1 - 7e-48 162.6 0.4 3.3e-26 92.4 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFL60598.1 - 6.7e-24 85.0 17.0 1e-23 84.3 16.8 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 KFL60598.1 - 2.2e-10 40.9 4.8 0.0065 16.3 0.1 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFL60598.1 - 4.5e-07 29.9 0.6 0.00056 19.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFL60598.1 - 5.4e-07 29.3 0.7 0.0056 16.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFL60598.1 - 2.1e-06 28.4 1.3 0.0024 18.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFL60598.1 - 5.7e-06 26.8 0.3 0.0087 16.5 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KFL60598.1 - 6.3e-06 25.8 3.0 0.031 13.7 0.1 4.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFL60598.1 - 2.2e-05 24.5 0.1 0.079 13.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 KFL60598.1 - 0.0001 22.7 0.1 0.019 15.4 0.0 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFL60598.1 - 0.00026 21.2 3.2 0.16 12.3 0.5 2.9 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.6 KFL60598.1 - 0.00029 21.2 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KFL60598.1 - 0.00061 19.6 0.6 0.021 14.5 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KFL60598.1 - 0.0021 17.6 0.2 0.42 10.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KFL60598.1 - 0.0024 17.6 0.8 0.39 10.4 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.23 KFL60598.1 - 0.0025 17.9 0.3 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 Dynamin family ATPase_2 PF01637.18 KFL60598.1 - 0.0032 17.4 0.5 0.27 11.1 0.1 2.8 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 KFL60598.1 - 0.004 16.3 0.2 0.54 9.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KFL60598.1 - 0.0053 17.1 0.1 1.9 8.9 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_24 PF13479.6 KFL60598.1 - 0.0055 16.4 0.0 3.9 7.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFL60598.1 - 0.0061 15.6 0.3 0.12 11.4 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.22 KFL60598.1 - 0.0062 15.8 3.4 0.25 10.5 0.5 2.6 2 1 0 2 2 2 1 NB-ARC domain ABC_ATPase PF09818.9 KFL60598.1 - 0.011 14.6 0.3 0.78 8.5 0.1 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class MeaB PF03308.16 KFL60598.1 - 0.016 14.2 0.3 0.71 8.8 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KFL60598.1 - 0.023 14.4 0.0 0.97 9.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 KFL60598.1 - 0.023 14.3 4.3 0.12 12.0 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KFL60598.1 - 0.024 14.5 2.3 3.6 7.5 0.1 2.6 2 0 0 2 2 2 0 NTPase Adeno_IVa2 PF02456.15 KFL60598.1 - 0.026 13.3 0.3 0.12 11.1 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_14 PF13173.6 KFL60598.1 - 0.026 14.5 0.0 0.3 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFL60598.1 - 0.03 14.9 0.0 5.3 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFL60598.1 - 0.055 13.2 2.2 6.3 6.5 0.1 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_10 PF12846.7 KFL60598.1 - 0.062 12.2 1.0 8.6 5.2 0.1 2.4 2 1 0 2 2 2 0 AAA-like domain AAA_25 PF13481.6 KFL60598.1 - 0.063 12.8 0.2 1.2 8.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KFL60598.1 - 0.064 12.9 0.1 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 KFL60598.1 - 0.077 12.3 0.1 7.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Herpes_Helicase PF02689.14 KFL60598.1 - 0.092 10.6 0.1 6.6 4.5 0.0 2.1 2 0 0 2 2 2 0 Helicase NACHT PF05729.12 KFL60598.1 - 0.1 12.5 3.6 0.35 10.8 0.3 2.6 2 1 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 KFL60598.1 - 0.12 11.7 1.0 5.5 6.3 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family UCR_UQCRX_QCR9 PF05365.12 KFL60598.1 - 0.16 12.0 1.9 0.4 10.7 1.9 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Roc PF08477.13 KFL60598.1 - 0.16 12.2 0.2 24 5.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KFL60598.1 - 0.17 11.8 1.3 0.43 10.5 0.1 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_33 PF13671.6 KFL60598.1 - 0.25 11.5 0.9 4 7.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KFL60598.1 - 0.3 11.1 3.7 1 9.4 0.5 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_membrane PF00664.23 KFL60599.1 - 8.6e-24 84.6 17.8 1.4e-23 84.0 17.6 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFL60599.1 - 2.5e-22 79.9 0.1 8e-19 68.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFL60599.1 - 2.9e-05 24.0 0.1 0.0055 16.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFL60599.1 - 0.00025 21.0 0.0 0.00046 20.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KFL60599.1 - 0.00094 19.7 0.1 0.002 18.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KFL60599.1 - 0.0016 17.9 0.1 0.026 14.0 0.1 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFL60599.1 - 0.002 17.9 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KFL60599.1 - 0.003 17.9 0.1 0.0068 16.8 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFL60599.1 - 0.0032 17.9 0.0 0.016 15.6 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFL60599.1 - 0.0057 17.0 0.0 0.0096 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 KFL60599.1 - 0.0073 15.1 0.3 0.64 8.8 0.1 2.7 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 KFL60599.1 - 0.011 15.4 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KFL60599.1 - 0.029 14.4 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 KFL60599.1 - 0.054 13.1 0.2 0.098 12.2 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KFL60599.1 - 0.054 13.4 0.1 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KFL60599.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.23 KFL60599.1 - 0.06 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Dynamin family Adeno_IVa2 PF02456.15 KFL60599.1 - 0.065 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein NB-ARC PF00931.22 KFL60599.1 - 0.074 12.2 0.6 0.19 10.9 0.6 1.6 1 1 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 KFL60599.1 - 0.087 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain UCR_UQCRX_QCR9 PF05365.12 KFL60599.1 - 0.13 12.3 1.9 0.34 10.9 1.9 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like NACHT PF05729.12 KFL60599.1 - 0.13 12.1 0.3 0.28 11.1 0.3 1.7 1 1 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KFL60599.1 - 0.15 11.8 0.2 5.3 6.7 0.1 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KFL60599.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KFL60599.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KFL60599.1 - 0.18 11.7 0.1 0.36 10.7 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 KFL60599.1 - 0.33 11.2 3.3 0.13 12.5 0.5 1.7 2 0 0 2 2 1 0 AAA domain ABC_membrane PF00664.23 KFL60600.1 - 8.6e-24 84.6 17.8 1.4e-23 84.0 17.6 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFL60600.1 - 2.5e-22 79.9 0.1 8e-19 68.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFL60600.1 - 2.9e-05 24.0 0.1 0.0055 16.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFL60600.1 - 0.00025 21.0 0.0 0.00046 20.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KFL60600.1 - 0.00094 19.7 0.1 0.002 18.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KFL60600.1 - 0.0016 17.9 0.1 0.026 14.0 0.1 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFL60600.1 - 0.002 17.9 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KFL60600.1 - 0.003 17.9 0.1 0.0068 16.8 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFL60600.1 - 0.0032 17.9 0.0 0.016 15.6 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFL60600.1 - 0.0057 17.0 0.0 0.0096 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 KFL60600.1 - 0.0073 15.1 0.3 0.64 8.8 0.1 2.7 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 KFL60600.1 - 0.011 15.4 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KFL60600.1 - 0.029 14.4 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 KFL60600.1 - 0.054 13.1 0.2 0.098 12.2 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KFL60600.1 - 0.054 13.4 0.1 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KFL60600.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.23 KFL60600.1 - 0.06 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Dynamin family Adeno_IVa2 PF02456.15 KFL60600.1 - 0.065 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein NB-ARC PF00931.22 KFL60600.1 - 0.074 12.2 0.6 0.19 10.9 0.6 1.6 1 1 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 KFL60600.1 - 0.087 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain UCR_UQCRX_QCR9 PF05365.12 KFL60600.1 - 0.13 12.3 1.9 0.34 10.9 1.9 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like NACHT PF05729.12 KFL60600.1 - 0.13 12.1 0.3 0.28 11.1 0.3 1.7 1 1 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KFL60600.1 - 0.15 11.8 0.2 5.3 6.7 0.1 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KFL60600.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KFL60600.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KFL60600.1 - 0.18 11.7 0.1 0.36 10.7 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 KFL60600.1 - 0.33 11.2 3.3 0.13 12.5 0.5 1.7 2 0 0 2 2 1 0 AAA domain Peptidase_M19 PF01244.21 KFL60603.1 - 5e-61 206.6 0.7 5.9e-61 206.4 0.7 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Mesd PF10185.9 KFL60603.1 - 0.2 11.6 0.4 7.8 6.4 0.1 2.1 1 1 1 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor ABC2_membrane_3 PF12698.7 KFL60604.1 - 4.4 6.3 8.3 6 5.9 8.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein COesterase PF00135.28 KFL60605.1 - 2.4e-23 82.8 0.0 3.2e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFL60605.1 - 0.0032 17.4 0.0 0.0049 16.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFL60605.1 - 0.056 14.0 0.2 0.091 13.4 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.22 KFL60608.1 - 1.4e-43 149.3 0.0 1.6e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tymo_coat PF00983.18 KFL60608.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Tymovirus coat protein PDZ_1 PF12812.7 KFL60609.1 - 0.00077 19.4 0.0 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 PDZ-like domain PDZ_2 PF13180.6 KFL60609.1 - 0.016 15.5 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain 4HPAD_g_N PF18671.1 KFL60609.1 - 0.031 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Acyl-CoA_dh_1 PF00441.24 KFL60611.1 - 7.7e-30 104.1 2.4 9.1e-30 103.9 2.4 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KFL60611.1 - 5.6e-15 55.8 1.2 7.5e-15 55.4 1.2 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFL60611.1 - 0.00074 19.7 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFL60612.1 - 3.6e-23 82.4 0.1 4.2e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFL60612.1 - 5e-05 23.4 0.0 8.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF2644 PF10841.8 KFL60613.1 - 0.035 14.3 1.1 0.067 13.4 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) EF-hand_1 PF00036.32 KFL60614.1 - 1e-19 68.5 3.6 2.3e-08 33.0 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFL60614.1 - 4.9e-19 66.6 0.4 2.6e-06 26.9 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KFL60614.1 - 3.1e-16 59.6 1.6 2.3e-06 27.9 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFL60614.1 - 2.5e-13 48.9 8.4 1.6e-05 24.2 0.0 3.9 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFL60614.1 - 1.1e-11 44.4 7.2 3.1e-06 26.9 1.0 3.3 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 KFL60614.1 - 1.9e-06 27.8 1.9 0.0033 17.4 0.1 2.8 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFL60614.1 - 0.0066 16.7 0.1 0.12 12.7 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KFL60614.1 - 0.025 14.9 0.1 0.92 9.9 0.0 2.3 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region RT_RNaseH PF17917.1 KFL60614.1 - 0.065 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase EMP70 PF02990.16 KFL60615.1 - 3.7e-193 642.9 3.7 4.3e-193 642.7 3.7 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 EMP70 PF02990.16 KFL60616.1 - 1e-136 456.7 0.0 1.2e-136 456.4 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Glyco_hydro_16 PF00722.21 KFL60616.1 - 0.11 12.0 0.7 0.4 10.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolases family 16 TssN PF17555.2 KFL60616.1 - 2.5 7.4 12.3 0.38 10.1 7.5 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssN EMP70 PF02990.16 KFL60617.1 - 1e-136 456.7 0.0 1.2e-136 456.4 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Glyco_hydro_16 PF00722.21 KFL60617.1 - 0.11 12.0 0.7 0.4 10.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolases family 16 TssN PF17555.2 KFL60617.1 - 2.5 7.4 12.3 0.38 10.1 7.5 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssN Acyl_transf_1 PF00698.21 KFL60618.1 - 1.2e-24 87.5 0.0 1.9e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 KFL60618.1 - 2.1e-24 86.1 0.0 4.9e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Ketoacyl-synt_C PF02801.22 KFL60618.1 - 3e-22 78.8 0.1 5.8e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KFL60619.1 - 1.2e-43 149.1 0.2 1.7e-43 148.7 0.2 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 KFL60619.1 - 2.6e-11 44.7 0.0 8e-11 43.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KFL60619.1 - 5.7e-05 22.7 0.1 9.5e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KFL60619.1 - 0.00013 22.0 0.0 0.0004 20.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KFL60619.1 - 0.03 13.9 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase APH PF01636.23 KFL60622.1 - 8.3e-07 29.2 0.0 9.2e-06 25.7 0.0 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFL60622.1 - 0.0098 15.5 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase CFEM PF05730.11 KFL60623.1 - 7.8e-10 38.7 0.8 1.1e-09 38.2 0.8 1.2 1 0 0 1 1 1 1 CFEM domain UQ_con PF00179.26 KFL60624.1 - 1.2e-33 115.7 0.0 4.3e-31 107.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Thiolase_N PF00108.23 KFL60625.1 - 1.5e-92 309.6 1.4 1.9e-92 309.3 1.4 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFL60625.1 - 1.4e-12 47.3 1.0 2.5e-12 46.5 0.1 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFL60625.1 - 7.5e-05 22.4 0.4 0.00016 21.3 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFL60625.1 - 0.004 17.0 0.3 2 8.3 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KFL60626.1 - 1.6e-77 260.4 1.5 2.1e-77 260.0 1.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFL60626.1 - 1.4e-37 128.1 0.6 1.4e-37 128.1 0.6 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFL60626.1 - 9.3e-05 22.1 0.2 0.00024 20.8 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFL60626.1 - 0.0052 16.6 2.2 1.8 8.5 0.0 3.2 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 5_nucleotid_C PF02872.18 KFL60627.1 - 3e-37 128.3 0.0 4.5e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KFL60627.1 - 0.017 15.6 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Cation_efflux PF01545.21 KFL60631.1 - 6.6e-20 71.7 2.0 1.7e-19 70.4 2.0 1.7 1 1 0 1 1 1 1 Cation efflux family DUF202 PF02656.15 KFL60631.1 - 3.7e-17 62.5 1.4 3.7e-17 62.5 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Methyltransf_23 PF13489.6 KFL60632.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DRE2_N PF16803.5 KFL60632.1 - 0.24 11.6 0.0 0.36 11.1 0.0 1.2 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Ribosomal_L5_C PF00673.21 KFL60636.1 - 3.3e-22 78.5 0.0 4.8e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KFL60636.1 - 2e-20 72.9 0.0 7.4e-20 71.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5 PF00281.19 KFL60637.1 - 1.4e-20 73.4 0.1 4.4e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KFL60637.1 - 4.7e-20 71.6 0.1 7.3e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KFL60638.1 - 1.3e-20 73.4 0.1 4.2e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KFL60638.1 - 4.5e-20 71.6 0.1 7e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus CPSase_L_D2 PF02786.17 KFL60639.1 - 1.3e-80 269.9 0.1 2.1e-80 269.2 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KFL60639.1 - 2.7e-69 232.9 0.0 4.5e-69 232.2 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KFL60639.1 - 1.4e-39 135.0 0.1 2.8e-39 134.0 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFL60639.1 - 9.1e-31 106.2 0.0 1.9e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KFL60639.1 - 8.8e-23 81.2 0.0 1.9e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Dala_Dala_lig_C PF07478.13 KFL60639.1 - 8e-09 35.3 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFL60639.1 - 5.9e-07 29.2 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.22 KFL60639.1 - 7.1e-06 25.8 0.7 1.9e-05 24.4 0.2 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KFL60639.1 - 4.1e-05 23.3 1.1 0.00013 21.7 0.1 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KFL60639.1 - 0.00011 22.2 0.0 0.00029 20.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KFL60639.1 - 0.00047 19.8 0.0 0.00097 18.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 KFL60639.1 - 0.016 14.5 0.1 0.036 13.3 0.1 1.5 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 KFL60639.1 - 0.023 14.3 0.0 0.35 10.4 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain ATF7IP_BD PF16788.5 KFL60642.1 - 0.32 11.1 0.8 0.6 10.2 0.6 1.5 1 1 0 1 1 1 0 ATF-interacting protein binding domain DUF2527 PF10736.9 KFL60643.1 - 0.02 14.7 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) CHCH PF06747.13 KFL60644.1 - 1.6e-05 24.9 4.2 3.3e-05 23.9 4.0 1.7 1 1 1 2 2 2 1 CHCH domain MTCP1 PF08991.10 KFL60644.1 - 0.00045 20.4 1.4 0.0006 20.0 1.4 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 KFL60644.1 - 0.044 14.1 5.2 0.082 13.2 4.3 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 KFL60644.1 - 0.061 13.7 2.6 0.42 11.0 1.4 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 KFL60644.1 - 0.1 12.9 3.6 0.17 12.2 3.6 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Clathrin PF00637.20 KFL60645.1 - 0.053 13.4 0.9 3.4 7.5 0.1 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS NatB_MDM20 PF09797.9 KFL60646.1 - 3.1e-95 319.4 0.8 4.6e-95 318.8 0.8 1.2 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KFL60646.1 - 0.00059 20.3 0.9 0.0036 17.8 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat HATPase_c PF02518.26 KFL60647.1 - 6.7e-19 68.5 0.0 1.4e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFL60647.1 - 3.5e-15 56.1 0.5 2.6e-09 37.2 0.1 3.2 2 1 0 2 2 2 2 Response regulator receiver domain HATPase_c_3 PF13589.6 KFL60647.1 - 0.032 14.1 0.0 0.097 12.5 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPX PF03105.19 KFL60647.1 - 8 6.3 20.0 0.29 11.0 8.9 2.3 2 0 0 2 2 2 0 SPX domain TFIIA PF03153.13 KFL60647.1 - 9.1 6.2 21.4 2.8 7.8 18.6 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Enolase_C PF00113.22 KFL60648.1 - 1.9e-154 513.2 0.0 2.4e-154 512.9 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFL60648.1 - 4.9e-35 120.6 0.1 9.5e-35 119.6 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KFL60648.1 - 8e-06 25.6 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like VSP PF03302.13 KFL60648.1 - 0.13 11.1 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Enolase_C PF00113.22 KFL60649.1 - 2.8e-89 299.3 0.1 4e-89 298.8 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFL60649.1 - 2.2e-56 189.6 0.2 3.1e-56 189.1 0.2 1.2 1 0 0 1 1 1 1 Enolase, N-terminal domain VSP PF03302.13 KFL60649.1 - 0.1 11.5 0.1 0.14 11.0 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein 14-3-3 PF00244.20 KFL60650.1 - 3.7e-100 334.0 2.0 4.5e-100 333.7 2.0 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF4164 PF13747.6 KFL60650.1 - 0.11 12.8 2.0 0.35 11.2 0.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Ima1_N PF09779.9 KFL60650.1 - 0.88 10.4 3.2 2 9.3 0.1 2.6 3 0 0 3 3 3 0 Ima1 N-terminal domain 14-3-3 PF00244.20 KFL60651.1 - 5.6e-63 212.4 0.1 6.8e-63 212.1 0.1 1.0 1 0 0 1 1 1 1 14-3-3 protein Ima1_N PF09779.9 KFL60651.1 - 0.046 14.6 0.0 1.3 9.8 0.0 2.7 3 0 0 3 3 3 0 Ima1 N-terminal domain Orbi_VP5 PF00901.17 KFL60651.1 - 0.091 11.1 0.8 0.12 10.8 0.8 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF4164 PF13747.6 KFL60651.1 - 0.11 12.8 0.3 0.26 11.6 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) TPR_7 PF13176.6 KFL60651.1 - 0.12 12.5 0.2 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C98 PF15499.6 KFL60651.1 - 0.12 11.8 0.3 0.22 11.0 0.2 1.3 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase E1-E2_ATPase PF00122.20 KFL60652.1 - 5.2e-50 169.5 7.7 4.4e-49 166.5 1.9 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFL60652.1 - 2.1e-47 161.2 7.4 2.1e-47 161.2 7.4 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFL60652.1 - 8.4e-22 78.5 0.2 3.2e-21 76.6 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFL60652.1 - 7.4e-19 67.2 0.1 2.8e-18 65.3 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFL60652.1 - 3.5e-16 59.1 0.0 7.1e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFL60652.1 - 4.3e-08 33.2 1.2 8.4e-06 25.7 0.9 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFL60652.1 - 3e-06 27.8 0.0 1.1e-05 26.0 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Inhibitor_I9 PF05922.16 KFL60653.1 - 5.9e-16 58.9 0.4 1e-15 58.2 0.4 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 KFL60653.1 - 7.3e-15 55.0 10.0 1.7e-14 53.8 10.0 1.6 1 1 0 1 1 1 1 Subtilase family MFS_1 PF07690.16 KFL60654.1 - 1.8e-17 63.3 13.9 1.8e-17 63.3 13.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL60654.1 - 0.00093 18.2 2.1 0.00093 18.2 2.1 2.9 3 2 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 KFL60655.1 - 1.7e-17 63.4 14.9 2.2e-17 63.0 14.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL60655.1 - 0.00085 18.3 2.1 0.00085 18.3 2.1 2.5 3 1 0 3 3 3 1 Sugar (and other) transporter PTR2 PF00854.21 KFL60655.1 - 0.0011 17.9 0.0 0.0023 16.8 0.0 1.5 1 0 0 1 1 1 1 POT family FPN1 PF06963.12 KFL60655.1 - 0.014 14.0 0.1 0.067 11.7 0.0 2.0 2 1 0 2 2 2 0 Ferroportin1 (FPN1) MFS_1 PF07690.16 KFL60656.1 - 1.7e-17 63.4 14.9 2.2e-17 63.0 14.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL60656.1 - 0.00085 18.3 2.1 0.00085 18.3 2.1 2.5 3 1 0 3 3 3 1 Sugar (and other) transporter PTR2 PF00854.21 KFL60656.1 - 0.0011 17.9 0.0 0.0023 16.8 0.0 1.5 1 0 0 1 1 1 1 POT family FPN1 PF06963.12 KFL60656.1 - 0.014 14.0 0.1 0.067 11.7 0.0 2.0 2 1 0 2 2 2 0 Ferroportin1 (FPN1) Frag1 PF10277.9 KFL60657.1 - 2.5e-07 30.5 3.9 3e-07 30.2 3.9 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3995 PF13160.6 KFL60657.1 - 0.028 14.8 0.5 0.04 14.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) XendoU PF09412.10 KFL60658.1 - 0.028 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Endoribonuclease XendoU DUF4407 PF14362.6 KFL60659.1 - 0.44 9.9 9.9 0.49 9.7 9.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ecm29 PF13001.7 KFL60660.1 - 2.9e-153 511.2 0.2 4.7e-150 500.6 0.0 4.1 3 1 1 4 4 4 2 Proteasome stabiliser HEAT PF02985.22 KFL60660.1 - 7.7e-05 22.6 5.4 0.61 10.5 0.1 8.2 10 0 0 10 10 10 1 HEAT repeat HEAT_EZ PF13513.6 KFL60660.1 - 0.0018 18.7 4.8 0.57 10.8 0.0 5.8 5 0 0 5 5 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFL60660.1 - 0.026 15.1 1.9 0.31 11.7 0.1 3.8 4 2 0 4 4 4 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KFL60660.1 - 0.29 10.2 11.2 3.3 6.7 0.6 4.7 4 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Ecm29 PF13001.7 KFL60661.1 - 2.9e-153 511.2 0.2 4.7e-150 500.6 0.0 4.1 3 1 1 4 4 4 2 Proteasome stabiliser HEAT PF02985.22 KFL60661.1 - 7.7e-05 22.6 5.4 0.61 10.5 0.1 8.2 10 0 0 10 10 10 1 HEAT repeat HEAT_EZ PF13513.6 KFL60661.1 - 0.0018 18.7 4.8 0.57 10.8 0.0 5.8 5 0 0 5 5 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFL60661.1 - 0.026 15.1 1.9 0.31 11.7 0.1 3.8 4 2 0 4 4 4 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KFL60661.1 - 0.29 10.2 11.2 3.3 6.7 0.6 4.7 4 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Ecm29 PF13001.7 KFL60662.1 - 2.9e-153 511.2 0.2 4.7e-150 500.6 0.0 4.1 3 1 1 4 4 4 2 Proteasome stabiliser HEAT PF02985.22 KFL60662.1 - 7.7e-05 22.6 5.4 0.61 10.5 0.1 8.2 10 0 0 10 10 10 1 HEAT repeat HEAT_EZ PF13513.6 KFL60662.1 - 0.0018 18.7 4.8 0.57 10.8 0.0 5.8 5 0 0 5 5 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFL60662.1 - 0.026 15.1 1.9 0.31 11.7 0.1 3.8 4 2 0 4 4 4 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KFL60662.1 - 0.29 10.2 11.2 3.3 6.7 0.6 4.7 4 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Stm1_N PF09598.10 KFL60663.1 - 0.016 16.0 4.1 0.036 14.9 4.1 1.5 1 0 0 1 1 1 0 Stm1 Stm1_N PF09598.10 KFL60664.1 - 0.016 16.0 4.1 0.036 14.9 4.1 1.5 1 0 0 1 1 1 0 Stm1 Fungal_trans_2 PF11951.8 KFL60665.1 - 1e-10 41.0 0.0 1.1e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4231 PF14015.6 KFL60668.1 - 0.072 13.6 0.7 0.081 13.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) ABC2_membrane_2 PF12679.7 KFL60668.1 - 0.17 11.1 3.0 0.19 10.9 3.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Phage_holin_2_2 PF10746.9 KFL60668.1 - 0.2 11.4 1.7 0.43 10.3 1.7 1.7 1 1 0 1 1 1 0 Phage holin T7 family, holin superfamily II MDM31_MDM32 PF08118.11 KFL60670.1 - 2.6e-249 828.3 2.2 1.8e-248 825.5 2.2 1.9 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Iso_dh PF00180.20 KFL60671.1 - 2.7e-79 266.9 0.0 3.1e-79 266.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.20 KFL60672.1 - 6.6e-84 282.0 0.0 8e-84 281.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.20 KFL60673.1 - 1.9e-79 267.3 0.0 2.2e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TPR_14 PF13428.6 KFL60675.1 - 2e-08 34.3 0.6 0.021 15.6 0.0 3.6 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFL60675.1 - 1.5e-06 28.6 0.0 0.059 13.9 0.0 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFL60675.1 - 5.8e-06 26.1 0.0 0.0097 16.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFL60675.1 - 7.5e-05 22.8 0.0 0.11 12.9 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFL60675.1 - 0.00018 21.3 0.4 0.12 12.5 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KFL60675.1 - 0.0036 17.2 0.0 0.81 9.6 0.0 2.3 1 1 1 2 2 2 2 Virulence factor membrane-bound polymerase, C-terminal TPR_16 PF13432.6 KFL60675.1 - 0.025 15.2 0.4 2 9.1 0.0 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFL60675.1 - 0.067 13.0 0.0 0.94 9.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFL60675.1 - 0.083 13.1 0.8 0.19 11.9 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFL60675.1 - 0.14 12.5 0.9 19 5.6 0.1 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFL60675.1 - 0.14 11.8 0.0 5.1 6.9 0.0 2.8 1 1 1 2 2 2 0 TPR repeat PCI PF01399.27 KFL60680.1 - 5.9e-11 42.8 0.0 1.7e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 KFL60680.1 - 2.2e-10 40.1 3.6 4.4e-10 39.1 3.6 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix UME PF08064.13 KFL60680.1 - 0.077 12.9 0.3 0.64 10.0 0.0 2.5 2 0 0 2 2 2 0 UME (NUC010) domain DUF883 PF05957.13 KFL60680.1 - 0.27 11.9 12.0 0.15 12.7 3.8 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) FliT PF05400.13 KFL60680.1 - 0.59 11.0 7.6 0.41 11.5 3.3 2.7 2 0 0 2 2 2 0 Flagellar protein FliT Cnd2 PF05786.14 KFL60683.1 - 0 1021.6 6.1 0 1021.4 6.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KFL60683.1 - 0.016 15.4 2.3 0.016 15.4 0.0 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal LRR_4 PF12799.7 KFL60685.1 - 1.3e-06 28.7 3.5 1.7 9.2 0.0 6.7 6 2 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFL60685.1 - 9.1e-06 25.3 5.2 1.3 9.3 0.0 5.9 7 0 0 7 7 7 3 Leucine Rich repeat LRR_8 PF13855.6 KFL60685.1 - 0.025 14.3 3.4 6.4 6.6 0.0 5.1 6 1 0 6 6 6 0 Leucine rich repeat CDC27 PF09507.10 KFL60686.1 - 1.2 8.4 24.0 0.092 12.1 18.4 1.8 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SAPS PF04499.15 KFL60686.1 - 3.8 6.2 12.9 5.2 5.7 12.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HSP70 PF00012.20 KFL60686.1 - 4.2 5.4 14.8 6 4.9 14.8 1.2 1 0 0 1 1 1 0 Hsp70 protein Miga PF10265.9 KFL60686.1 - 6.1 5.7 10.0 7.7 5.4 10.0 1.2 1 0 0 1 1 1 0 Mitoguardin Ras PF00071.22 KFL60688.1 - 2.3e-56 189.9 0.4 3e-56 189.5 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL60688.1 - 7.3e-33 113.3 0.2 1.2e-32 112.6 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL60688.1 - 1.3e-14 54.0 0.6 1.6e-14 53.7 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL60688.1 - 1.1e-05 25.1 0.2 2.9e-05 23.7 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFL60688.1 - 0.0011 18.5 0.1 0.0017 17.9 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFL60688.1 - 0.0017 18.4 0.1 0.0037 17.3 0.1 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFL60688.1 - 0.0052 16.7 0.0 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KFL60688.1 - 0.014 14.7 0.2 0.018 14.4 0.2 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TetR_C_16 PF17920.1 KFL60688.1 - 0.18 12.0 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ras PF00071.22 KFL60689.1 - 6.4e-60 201.4 0.5 8e-60 201.1 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL60689.1 - 9.4e-37 125.9 0.2 1.4e-36 125.4 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL60689.1 - 3.9e-18 65.5 0.4 4.7e-18 65.3 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL60689.1 - 3.6e-06 26.7 0.1 2.4e-05 24.0 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFL60689.1 - 1.2e-05 25.3 0.1 2.4e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFL60689.1 - 1.2e-05 24.8 0.0 2.2e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFL60689.1 - 1.8e-05 24.7 0.2 0.021 14.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFL60689.1 - 4.7e-05 22.9 0.2 5.6e-05 22.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KFL60689.1 - 0.059 12.9 0.0 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KFL60689.1 - 0.073 13.1 0.3 8.2 6.4 0.0 2.6 2 1 0 2 2 2 0 Dynamin family TetR_C_16 PF17920.1 KFL60689.1 - 0.18 12.1 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ras PF00071.22 KFL60690.1 - 1.8e-56 190.2 0.4 2.3e-56 189.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL60690.1 - 6.1e-33 113.6 0.2 9.7e-33 112.9 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL60690.1 - 1e-14 54.4 0.6 1.2e-14 54.1 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL60690.1 - 8.7e-06 25.4 0.2 2.2e-05 24.1 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFL60690.1 - 0.00091 18.7 0.1 0.0012 18.3 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFL60690.1 - 0.0014 18.7 0.1 0.003 17.6 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFL60690.1 - 0.0042 17.0 0.0 0.018 15.0 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KFL60690.1 - 0.011 15.0 0.2 0.014 14.7 0.2 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TetR_C_16 PF17920.1 KFL60690.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ras PF00071.22 KFL60691.1 - 5.1e-42 143.2 0.1 6.3e-42 142.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL60691.1 - 4.6e-20 72.0 0.1 7.8e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL60691.1 - 1.5e-11 44.1 0.5 1.9e-11 43.7 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL60691.1 - 0.0001 21.9 0.1 0.00019 21.0 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFL60691.1 - 0.0076 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase TetR_C_16 PF17920.1 KFL60691.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ras PF00071.22 KFL60692.1 - 5.1e-42 143.2 0.1 6.3e-42 142.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL60692.1 - 4.6e-20 72.0 0.1 7.8e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL60692.1 - 1.5e-11 44.1 0.5 1.9e-11 43.7 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL60692.1 - 0.0001 21.9 0.1 0.00019 21.0 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFL60692.1 - 0.0076 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase TetR_C_16 PF17920.1 KFL60692.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ATP-synt_C PF00137.21 KFL60693.1 - 1.1e-18 67.3 22.1 1.3e-16 60.7 10.8 2.5 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 KFL60693.1 - 0.058 12.7 0.7 0.085 12.2 0.7 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 MoeA_N PF03453.17 KFL60694.1 - 1.2e-38 132.3 2.2 2e-38 131.7 2.2 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KFL60694.1 - 4.9e-27 94.4 0.0 3.8e-22 78.5 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_C PF03454.15 KFL60694.1 - 3.4e-18 65.6 0.1 9.5e-18 64.2 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DUF866 PF05907.13 KFL60695.1 - 2.3e-59 199.7 1.5 3.9e-59 199.0 0.6 1.7 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.22 KFL60695.1 - 3e-19 68.5 0.3 5.3e-19 67.7 0.3 1.4 1 0 0 1 1 1 1 LSM domain HalOD2 PF18547.1 KFL60695.1 - 0.048 13.6 3.0 0.31 11.0 3.1 2.3 1 1 0 1 1 1 0 Halobacterial output domain 2 DUF4379 PF14311.6 KFL60695.1 - 0.13 12.6 1.0 0.24 11.8 0.2 1.9 1 1 0 1 1 1 0 Probable Zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KFL60695.1 - 0.19 11.7 2.4 15 5.6 0.4 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain FAD_binding_1 PF00667.20 KFL60698.1 - 2.2e-67 226.9 0.0 3.1e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFL60698.1 - 4.9e-35 120.8 0.8 9.5e-35 119.9 0.8 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFL60698.1 - 1.5e-21 77.1 0.0 1.4e-20 73.9 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFL60698.1 - 0.095 12.9 0.1 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Flavodoxin domain Apelin PF15360.6 KFL60699.1 - 0.78 10.3 5.7 0.36 11.4 2.2 2.3 1 1 1 2 2 2 0 APJ endogenous ligand NUDIX PF00293.28 KFL60701.1 - 5.3e-27 94.4 0.0 6.9e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KFL60702.1 - 2.3e-14 53.6 0.0 3.2e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain CPSF_A PF03178.15 KFL60703.1 - 1.5e-92 310.4 0.0 1.7e-92 310.2 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region Gly-zipper_Omp PF13488.6 KFL60705.1 - 7e-05 22.7 23.6 4.8e+02 0.9 23.6 4.0 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 KFL60705.1 - 0.011 15.5 17.2 1.4e+02 2.3 17.2 3.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper DUF456 PF04306.13 KFL60705.1 - 1.5 9.1 26.4 3.1 8.1 11.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF456) MccV PF17508.2 KFL60705.1 - 1.5 9.4 9.3 5.1 7.7 1.3 2.6 2 1 1 3 3 3 0 Microcin V bacteriocin DUF697 PF05128.12 KFL60705.1 - 3.1 7.5 5.4 0.38 10.5 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF697) APH PF01636.23 KFL60710.1 - 0.00069 19.6 0.0 0.00069 19.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family VPS38 PF17649.1 KFL60711.1 - 0.17 10.7 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 DDT PF02791.17 KFL60712.1 - 0.042 14.2 0.1 0.14 12.5 0.1 1.9 1 1 0 1 1 1 0 DDT domain Thiolase_N PF00108.23 KFL60714.1 - 2.3e-52 177.9 0.2 3.8e-52 177.2 0.1 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFL60714.1 - 1.9e-44 150.2 1.1 3e-44 149.6 1.1 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain FeS_assembly_P PF01883.19 KFL60715.1 - 1.7e-10 40.9 0.0 4.3e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Pheromone PF08015.11 KFL60715.1 - 0.38 11.8 2.5 2.2 9.4 0.0 2.9 2 1 0 2 2 2 0 Fungal mating-type pheromone ANAPC_CDC26 PF10471.9 KFL60716.1 - 6.7e-20 71.7 1.1 8.1e-20 71.4 1.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 tRNA-synt_2c PF01411.19 KFL60717.1 - 9.9e-167 555.8 0.0 9.9e-167 555.8 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KFL60717.1 - 4e-18 65.2 0.6 1.2e-17 63.8 0.6 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KFL60717.1 - 2.6e-14 53.8 1.4 2.6e-14 53.8 1.4 2.1 2 0 0 2 2 2 1 DHHA1 domain FIN1 PF17300.2 KFL60717.1 - 0.45 10.0 3.1 0.77 9.2 3.1 1.2 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Peptidase_S10 PF00450.22 KFL60718.1 - 2.9e-23 82.9 0.0 3.5e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase FGGY_N PF00370.21 KFL60719.1 - 9.6e-69 231.6 0.0 1.3e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFL60719.1 - 5.4e-57 192.7 0.4 1.1e-56 191.7 0.1 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Abhydrolase_6 PF12697.7 KFL60720.1 - 2.3e-16 61.1 0.1 3.2e-16 60.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFL60720.1 - 0.051 13.0 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Frigida PF07899.11 KFL60720.1 - 0.052 12.8 0.0 0.074 12.3 0.0 1.1 1 0 0 1 1 1 0 Frigida-like protein Abhydrolase_1 PF00561.20 KFL60720.1 - 0.071 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KFL60720.1 - 0.075 12.7 0.0 0.17 11.6 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Hydrolase_4 PF12146.8 KFL60720.1 - 0.083 12.1 0.0 0.12 11.6 0.0 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 VirB8 PF04335.13 KFL60720.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 VirB8 protein DSBA PF01323.20 KFL60724.1 - 1e-07 32.0 0.0 1.1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain G-patch PF01585.23 KFL60726.1 - 5.5e-11 42.2 1.8 2.4e-09 36.9 1.8 2.4 1 1 0 1 1 1 1 G-patch domain MyTH4 PF00784.17 KFL60726.1 - 0.12 12.9 0.5 0.17 12.4 0.5 1.3 1 0 0 1 1 1 0 MyTH4 domain DUF4187 PF13821.6 KFL60727.1 - 5.2e-22 77.4 1.9 5.2e-22 77.4 1.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) CHASE8 PF17152.4 KFL60727.1 - 0.057 13.7 0.9 0.085 13.1 0.9 1.3 1 1 0 1 1 1 0 Periplasmic sensor domain FluMu_N PF17891.1 KFL60728.1 - 0.21 11.4 1.7 0.72 9.7 0.2 2.6 3 1 1 4 4 4 0 Mu-like prophage FluMu N-terminal domain pPIWI_RE_X PF13111.6 KFL60729.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.0 1 0 0 1 1 1 0 pPIWI_RE module N-terminal domain SET PF00856.28 KFL60730.1 - 1.8e-12 48.0 0.0 5.3e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 SET domain Rtf2 PF04641.12 KFL60730.1 - 0.00012 21.6 0.2 0.00019 20.9 0.2 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger Ribosomal_S19 PF00203.21 KFL60731.1 - 8.9e-30 102.4 0.1 1.2e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FTP PF07504.13 KFL60733.1 - 1.5e-10 40.7 0.1 2.5e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M36 PF02128.15 KFL60734.1 - 7.3e-69 232.7 0.0 8.2e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 KFL60734.1 - 0.029 14.2 0.0 0.044 13.6 0.0 1.6 1 1 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Coiled-coil_56 PF09813.9 KFL60735.1 - 0.0024 17.9 0.0 0.0024 17.9 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 SMN PF06003.12 KFL60736.1 - 0.097 11.9 2.7 0.18 11.1 2.7 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) MEF2_binding PF09047.10 KFL60738.1 - 0.046 13.6 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 MEF2 binding STT3 PF02516.14 KFL60739.1 - 3.8e-124 415.3 33.2 1.3e-118 397.0 31.6 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PWWP PF00855.17 KFL60740.1 - 4.8e-15 55.7 6.7 4.8e-15 55.7 6.7 3.6 2 1 0 2 2 2 1 PWWP domain MutS_V PF00488.21 KFL60742.1 - 7e-74 247.9 0.0 1.3e-73 247.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFL60742.1 - 1.8e-17 64.2 0.6 3.7e-17 63.2 0.6 1.6 1 0 0 1 1 1 1 MutS domain III AAA_14 PF13173.6 KFL60742.1 - 0.021 14.8 0.0 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KFL60742.1 - 0.035 13.7 1.5 0.2 11.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KFL60742.1 - 0.038 13.7 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KFL60742.1 - 0.05 13.9 1.3 5.8 7.2 0.0 3.4 2 2 1 3 3 3 0 AAA domain MutS_IV PF05190.18 KFL60742.1 - 0.071 13.5 0.3 0.44 10.9 0.1 2.2 2 0 0 2 2 2 0 MutS family domain IV AAA_23 PF13476.6 KFL60742.1 - 0.14 12.6 3.2 0.18 12.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain Rer1 PF03248.13 KFL60743.1 - 1.3e-72 243.1 4.6 1.5e-72 242.9 4.6 1.0 1 0 0 1 1 1 1 Rer1 family MFS_1 PF07690.16 KFL60743.1 - 0.0026 16.8 4.3 0.0032 16.5 4.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1538 PF07556.11 KFL60743.1 - 0.3 10.4 5.3 1.4 8.2 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) Rer1 PF03248.13 KFL60744.1 - 2.1e-56 190.3 5.6 2.5e-56 190.1 5.6 1.0 1 0 0 1 1 1 1 Rer1 family DUF1538 PF07556.11 KFL60744.1 - 2.9 7.1 8.2 1.2 8.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) Mt_ATP-synt_B PF05405.14 KFL60747.1 - 3.6e-50 169.8 9.7 4.8e-50 169.4 9.7 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ribosomal_L50 PF10501.9 KFL60747.1 - 0.00028 21.0 1.2 0.057 13.6 0.0 2.5 2 0 0 2 2 2 2 Ribosomal subunit 39S Mt_ATP-synt_B PF05405.14 KFL60748.1 - 9.9e-25 87.0 0.2 1.5e-24 86.5 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ribosomal_L50 PF10501.9 KFL60748.1 - 0.018 15.2 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal subunit 39S Mt_ATP-synt_B PF05405.14 KFL60749.1 - 9.9e-25 87.0 0.2 1.5e-24 86.5 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ribosomal_L50 PF10501.9 KFL60749.1 - 0.018 15.2 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal subunit 39S CBF PF03914.17 KFL60750.1 - 3.5e-36 124.8 0.3 5.1e-36 124.3 0.3 1.3 1 0 0 1 1 1 1 CBF/Mak21 family MMS19_C PF12460.8 KFL60752.1 - 2e-119 399.4 11.8 2e-119 399.4 11.8 1.6 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal HEAT PF02985.22 KFL60752.1 - 0.85 10.1 7.6 22 5.6 0.3 4.7 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 KFL60752.1 - 1.2 9.6 6.0 1.5 9.3 0.6 3.5 4 1 0 4 4 4 0 HEAT repeats MMS19_N PF14500.6 KFL60753.1 - 6.7e-41 140.6 0.0 1e-40 140.0 0.0 1.2 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II ATP-synt_ab PF00006.25 KFL60754.1 - 2.2e-73 246.4 0.0 3e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KFL60754.1 - 1.3e-47 161.2 0.2 2.2e-47 160.5 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KFL60754.1 - 2.8e-08 34.2 0.9 6.7e-08 32.9 0.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3659 PF12396.8 KFL60754.1 - 0.094 12.6 0.6 18 5.3 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3659) ATP-synt_ab PF00006.25 KFL60755.1 - 2e-73 246.6 0.0 2.7e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KFL60755.1 - 1.3e-47 161.3 0.2 2e-47 160.6 0.2 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KFL60755.1 - 0.00055 20.4 0.3 0.0014 19.1 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3659 PF12396.8 KFL60755.1 - 0.092 12.7 0.6 17 5.4 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3659) DUF962 PF06127.11 KFL60756.1 - 3.3e-18 65.6 0.0 6e-18 64.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.17 KFL60757.1 - 3.7e-14 52.8 0.1 6e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KFL60757.1 - 4.3e-11 43.0 0.0 6.8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KFL60757.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KFL60758.1 - 2.2e-14 53.5 0.1 3.1e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KFL60758.1 - 1.1e-06 28.9 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain ERO1 PF04137.15 KFL60759.1 - 1.2e-134 449.0 0.0 1.7e-134 448.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) FliT PF05400.13 KFL60759.1 - 0.29 12.0 1.1 17 6.3 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein FliT ERO1 PF04137.15 KFL60760.1 - 1.1e-119 399.8 0.0 1.5e-119 399.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) FliT PF05400.13 KFL60760.1 - 0.22 12.4 1.1 14 6.5 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein FliT Peroxin-13_N PF04088.13 KFL60761.1 - 1.3e-53 181.2 0.1 2.3e-53 180.4 0.1 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KFL60761.1 - 6.3e-09 35.4 0.0 1.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFL60761.1 - 2.2e-07 30.4 0.0 4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFL60761.1 - 9.2e-06 25.4 0.1 1.7e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 KFL60761.1 - 0.2 12.1 0.0 0.35 11.3 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain zf-C2H2 PF00096.26 KFL60765.1 - 0.0028 18.0 5.9 0.0028 18.0 5.9 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type C1_4 PF07975.12 KFL60765.1 - 0.058 13.6 0.3 0.16 12.2 0.3 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_4 PF13894.6 KFL60765.1 - 1.2 10.2 18.3 0.08 13.8 4.9 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger YjbR PF04237.13 KFL60766.1 - 0.011 16.3 0.0 0.22 12.1 0.0 2.2 1 1 0 2 2 2 0 YjbR AAA PF00004.29 KFL60768.1 - 4e-41 140.5 0.0 6.6e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFL60768.1 - 2.6e-05 23.9 0.0 5.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFL60768.1 - 4e-05 23.9 0.0 0.0044 17.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KFL60768.1 - 6.4e-05 23.0 0.1 0.00029 20.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFL60768.1 - 0.00021 21.5 0.0 0.00046 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFL60768.1 - 0.00024 21.6 0.1 0.0051 17.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KFL60768.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KFL60768.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KFL60768.1 - 0.024 14.9 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFL60768.1 - 0.03 13.8 0.0 0.12 11.9 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFL60768.1 - 0.04 14.1 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFL60768.1 - 0.054 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KFL60768.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFL60768.1 - 0.071 12.8 0.1 0.21 11.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFL60768.1 - 0.085 13.4 0.0 0.34 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFL60768.1 - 0.12 12.3 0.0 8.8 6.2 0.0 2.3 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KFL60768.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFL60768.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 KFL60769.1 - 2.9e-41 141.0 0.0 4.5e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFL60769.1 - 2.3e-05 24.1 0.0 4.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFL60769.1 - 2.5e-05 24.6 0.0 0.0036 17.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KFL60769.1 - 6.5e-05 22.9 0.1 0.00021 21.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFL60769.1 - 0.00015 22.2 0.1 0.004 17.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KFL60769.1 - 0.00016 21.8 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KFL60769.1 - 0.0012 18.1 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KFL60769.1 - 0.0043 16.8 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KFL60769.1 - 0.021 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFL60769.1 - 0.028 13.9 0.0 0.088 12.3 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFL60769.1 - 0.031 14.4 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFL60769.1 - 0.047 14.1 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KFL60769.1 - 0.053 13.4 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFL60769.1 - 0.058 13.1 0.1 0.14 11.9 0.1 1.8 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFL60769.1 - 0.066 13.8 0.0 0.26 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFL60769.1 - 0.089 12.7 0.0 6.9 6.5 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KFL60769.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFL60769.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KFL60769.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFL60770.1 - 2.9e-41 141.0 0.0 4.5e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFL60770.1 - 2.3e-05 24.1 0.0 4.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFL60770.1 - 2.5e-05 24.6 0.0 0.0036 17.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KFL60770.1 - 6.5e-05 22.9 0.1 0.00021 21.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFL60770.1 - 0.00015 22.2 0.1 0.004 17.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KFL60770.1 - 0.00016 21.8 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KFL60770.1 - 0.0012 18.1 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KFL60770.1 - 0.0043 16.8 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KFL60770.1 - 0.021 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFL60770.1 - 0.028 13.9 0.0 0.088 12.3 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFL60770.1 - 0.031 14.4 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFL60770.1 - 0.047 14.1 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KFL60770.1 - 0.053 13.4 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFL60770.1 - 0.058 13.1 0.1 0.14 11.9 0.1 1.8 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFL60770.1 - 0.066 13.8 0.0 0.26 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFL60770.1 - 0.089 12.7 0.0 6.9 6.5 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KFL60770.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFL60770.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KFL60770.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.24 KFL60771.1 - 1.3e-138 462.7 13.8 1.5e-138 462.5 13.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 KFL60772.1 - 1.3e-138 462.7 13.8 1.5e-138 462.5 13.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 KFL60773.1 - 1.3e-128 429.7 11.9 1.4e-128 429.6 11.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 KFL60774.1 - 1.3e-128 429.7 11.9 1.4e-128 429.6 11.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 KFL60775.1 - 3e-99 332.9 6.8 3.3e-99 332.7 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 KFL60776.1 - 3e-99 332.9 6.8 3.3e-99 332.7 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family COX17 PF05051.13 KFL60777.1 - 2.7e-20 72.5 6.1 4.2e-20 71.8 6.1 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KFL60777.1 - 0.03 14.3 3.0 0.083 12.9 0.0 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pkinase PF00069.25 KFL60779.1 - 0.00082 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFL60779.1 - 0.0018 17.7 0.1 0.1 11.9 0.1 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFL60779.1 - 0.0032 17.4 0.0 0.0043 17.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFL60779.1 - 0.034 13.4 0.0 0.086 12.1 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase Secretin_N_2 PF07655.13 KFL60781.1 - 0.004 17.7 3.2 0.004 17.7 3.2 2.0 2 0 0 2 2 2 1 Secretin N-terminal domain RhoGAP PF00620.27 KFL60787.1 - 2.6e-16 59.8 0.1 4.4e-16 59.1 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain VWA_2 PF13519.6 KFL60788.1 - 1.4e-15 57.8 0.0 3.6e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFL60788.1 - 2.3e-05 24.7 0.1 3.4e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 KFL60788.1 - 0.015 15.2 0.3 0.038 13.9 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Ssl1 PF04056.14 KFL60788.1 - 0.049 13.4 0.1 0.071 12.9 0.1 1.2 1 0 0 1 1 1 0 Ssl1-like VWA_2 PF13519.6 KFL60789.1 - 5.2e-09 36.7 0.0 1.5e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.20 KFL60789.1 - 0.012 15.5 0.3 0.032 14.1 0.3 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif ANF_receptor PF01094.28 KFL60789.1 - 0.2 10.7 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region AA_kinase PF00696.28 KFL60792.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Amino acid kinase family APH PF01636.23 KFL60793.1 - 4.6e-07 30.0 0.1 8.8e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family HMG_CoA_synt_C PF08540.10 KFL60794.1 - 2.4e-98 329.2 2.3 2.7e-98 329.1 2.3 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal CHIPS PF11434.8 KFL60794.1 - 0.18 11.6 1.1 29 4.6 0.0 3.0 2 1 1 3 3 3 0 Chemotaxis-inhibiting protein CHIPS HMG_CoA_synt_N PF01154.17 KFL60795.1 - 1.8e-50 171.2 0.0 2e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Glyco_transf_64 PF09258.10 KFL60795.1 - 0.075 12.3 0.0 0.085 12.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain FAD_binding_4 PF01565.23 KFL60798.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain CD99L2 PF12301.8 KFL60798.1 - 0.13 12.6 0.1 0.24 11.7 0.1 1.5 1 1 1 2 2 2 0 CD99 antigen like protein 2 DUF2815 PF10991.8 KFL60798.1 - 0.19 11.7 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) Tubulin_C PF03953.17 KFL60800.1 - 1.3e-44 151.4 0.0 1.9e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFL60800.1 - 3.5e-39 135.1 0.0 4.7e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFL60800.1 - 0.00041 20.1 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_C PF03953.17 KFL60801.1 - 1.3e-44 151.4 0.0 1.9e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFL60801.1 - 3.5e-39 135.1 0.0 4.7e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFL60801.1 - 0.00041 20.1 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_C PF03953.17 KFL60802.1 - 1.3e-44 151.4 0.0 1.9e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFL60802.1 - 3.5e-39 135.1 0.0 4.7e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFL60802.1 - 0.00041 20.1 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_C PF03953.17 KFL60803.1 - 1.3e-44 151.4 0.0 1.9e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFL60803.1 - 3.5e-39 135.1 0.0 4.7e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFL60803.1 - 0.00041 20.1 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_C PF03953.17 KFL60804.1 - 1.3e-44 151.4 0.0 1.9e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFL60804.1 - 3.5e-39 135.1 0.0 4.7e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFL60804.1 - 0.00041 20.1 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain OPT PF03169.15 KFL60805.1 - 7.4e-68 229.7 22.7 8.5e-68 229.5 22.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 KFL60805.1 - 1.3 9.2 8.3 3.5 7.9 8.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) DUF4191 PF13829.6 KFL60805.1 - 3 7.1 5.5 6 6.2 5.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Bac_export_3 PF01313.19 KFL60805.1 - 5 7.1 11.3 0.48 10.4 4.0 2.8 2 1 0 2 2 2 0 Bacterial export proteins, family 3 OPT PF03169.15 KFL60806.1 - 6.3e-32 111.0 8.5 7.3e-32 110.8 8.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PA PF02225.22 KFL60807.1 - 6.3e-11 42.2 0.6 1.1e-09 38.2 0.4 2.8 2 1 0 2 2 2 1 PA domain Peptidase_M28 PF04389.17 KFL60807.1 - 2.6e-07 30.5 0.0 1e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 PRONE PF03759.13 KFL60807.1 - 0.043 12.6 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) Cyclin PF08613.11 KFL60810.1 - 1.5e-05 25.4 2.1 1.8e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 Cyclin Spt20 PF12090.8 KFL60810.1 - 0.057 13.0 4.9 0.059 13.0 4.9 1.1 1 0 0 1 1 1 0 Spt20 family Proteasome PF00227.26 KFL60812.1 - 5.3e-48 163.0 0.3 6.1e-48 162.8 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 KFL60813.1 - 5.8e-45 153.1 0.2 6.5e-45 153.0 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 KFL60814.1 - 5.8e-45 153.1 0.2 6.5e-45 153.0 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit RabGAP-TBC PF00566.18 KFL60815.1 - 8.3e-09 35.4 0.0 2.4e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KFL60815.1 - 5.7e-08 31.5 0.3 5.7e-08 31.5 0.3 2.0 2 0 0 2 2 2 1 SBE2, cell-wall formation Peptidase_C48 PF02902.19 KFL60816.1 - 2.1e-13 50.6 0.9 1.2e-12 48.2 0.9 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.19 KFL60817.1 - 1.8e-13 50.8 0.9 1e-12 48.3 0.9 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.19 KFL60818.1 - 4.6e-12 46.2 0.6 1.8e-11 44.3 0.6 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.19 KFL60819.1 - 4.6e-12 46.2 0.6 1.8e-11 44.3 0.6 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.19 KFL60820.1 - 4.6e-12 46.2 0.6 1.8e-11 44.3 0.6 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MCM PF00493.23 KFL60824.1 - 5.5e-103 342.9 0.0 8.1e-103 342.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFL60824.1 - 1.4e-31 109.0 0.1 2.3e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFL60824.1 - 1e-21 77.2 0.6 3.3e-21 75.5 0.6 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KFL60824.1 - 2.6e-07 30.2 0.0 4e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFL60824.1 - 1.7e-05 24.8 0.0 4.5e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 KFL60824.1 - 0.034 14.8 0.1 0.15 12.7 0.1 2.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal AAA_lid_2 PF17863.1 KFL60824.1 - 0.036 13.9 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA lid domain AAA_3 PF07726.11 KFL60824.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.23 KFL60825.1 - 0.039 12.7 0.0 0.046 12.4 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain CMAS PF02353.20 KFL60826.1 - 8.1e-56 189.3 0.0 1.1e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KFL60826.1 - 7.8e-09 35.6 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFL60826.1 - 1.9e-08 34.9 0.0 4.3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFL60826.1 - 2.5e-08 34.4 0.0 9e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFL60826.1 - 0.00049 20.8 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KFL60826.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 KFL60826.1 - 0.098 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KFL60826.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KFL60826.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 KFL60827.1 - 4.3e-61 206.6 0.0 5.3e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KFL60827.1 - 6.5e-09 35.8 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFL60827.1 - 1.5e-08 35.2 0.0 3.7e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFL60827.1 - 2e-08 34.7 0.0 7.7e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFL60827.1 - 0.0004 21.1 0.0 0.00092 19.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KFL60827.1 - 0.017 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 KFL60827.1 - 0.085 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KFL60827.1 - 0.092 12.5 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KFL60827.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KFL60827.1 - 0.21 11.3 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Replic_Relax PF13814.6 KFL60829.1 - 0.0025 17.9 0.3 0.0031 17.6 0.3 1.1 1 0 0 1 1 1 1 Replication-relaxation CCD48 PF15799.5 KFL60829.1 - 0.064 11.6 0.1 0.068 11.5 0.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Aldedh PF00171.22 KFL60831.1 - 2.9e-129 431.6 0.0 3.2e-129 431.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KFL60831.1 - 0.00018 20.7 0.0 0.00088 18.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Ank_2 PF12796.7 KFL60837.1 - 1.8e-31 108.5 0.0 3.1e-11 43.7 0.0 7.0 7 1 0 7 7 7 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFL60837.1 - 8.8e-25 84.1 2.6 0.0011 19.3 0.1 9.7 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.6 KFL60837.1 - 1.5e-23 82.9 1.6 0.0003 21.3 0.0 8.8 8 1 1 9 9 9 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFL60837.1 - 2.3e-19 69.2 7.3 0.0023 18.2 0.1 9.1 9 0 0 9 9 9 4 Ankyrin repeats (many copies) Ank PF00023.30 KFL60837.1 - 9.3e-16 57.5 6.9 0.00066 20.0 0.1 7.4 7 1 0 7 7 7 4 Ankyrin repeat Tim44 PF04280.15 KFL60837.1 - 0.01 16.0 0.0 1.5 8.9 0.0 2.8 2 0 0 2 2 2 0 Tim44-like domain PEMT PF04191.13 KFL60839.1 - 5.2e-61 203.6 8.4 6.8e-37 126.1 0.4 3.3 3 0 0 3 3 3 2 Phospholipid methyltransferase SKICH PF17751.1 KFL60839.1 - 0.03 14.9 0.1 1.2 9.8 0.0 2.4 2 0 0 2 2 2 0 SKICH domain HECW_N PF16562.5 KFL60839.1 - 0.044 13.6 0.1 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 PEMT PF04191.13 KFL60840.1 - 4.6e-61 203.8 8.4 6.5e-37 126.2 0.4 3.3 3 0 0 3 3 3 2 Phospholipid methyltransferase SKICH PF17751.1 KFL60840.1 - 0.03 14.9 0.1 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 SKICH domain HECW_N PF16562.5 KFL60840.1 - 0.043 13.6 0.1 0.13 12.0 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Bunya_G2 PF03563.13 KFL60843.1 - 0.037 13.3 0.1 0.044 13.0 0.1 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Bunya_G2 PF03563.13 KFL60844.1 - 0.037 13.3 0.1 0.044 13.0 0.1 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 AA_permease_2 PF13520.6 KFL60846.1 - 9.4e-21 74.1 22.7 1.2e-20 73.8 22.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFL60846.1 - 1.7e-11 43.4 21.8 2.2e-11 43.1 21.8 1.0 1 0 0 1 1 1 1 Amino acid permease Sprouty PF05210.13 KFL60846.1 - 0.069 13.5 1.0 2.1 8.8 0.0 2.7 3 1 0 3 3 3 0 Sprouty protein (Spry) Dynamin_N PF00350.23 KFL60847.1 - 0.021 14.9 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Dynamin family Dynamin_M PF01031.20 KFL60848.1 - 2.7e-18 66.2 0.0 3.5e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KFL60848.1 - 2.3e-13 50.6 0.1 4.2e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFL60848.1 - 0.034 14.2 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gln-synt_C PF00120.24 KFL60850.1 - 3.7e-50 170.9 0.0 1.4e-49 169.0 0.0 1.8 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 KFL60850.1 - 5.2e-14 52.7 0.0 8.9e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.16 KFL60851.1 - 9.6e-36 123.4 23.1 3.1e-35 121.8 23.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL60851.1 - 1e-13 51.0 11.5 1e-13 51.0 11.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KFL60851.1 - 0.0015 17.1 3.8 0.0023 16.4 3.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFA1_2 PF17317.2 KFL60851.1 - 0.16 11.8 0.8 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Mating hormone A-factor 1&2 Ribosomal_L21e PF01157.18 KFL60852.1 - 8.7e-31 105.8 4.1 8.7e-31 105.8 4.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e DUF5486 PF17588.2 KFL60852.1 - 0.23 11.4 3.0 0.93 9.4 0.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Strep_his_triad PF04270.13 KFL60852.1 - 0.54 10.3 1.8 4.6 7.3 0.2 2.7 1 1 1 2 2 2 0 Streptococcal histidine triad protein Mito_carr PF00153.27 KFL60853.1 - 8.8e-69 227.5 1.6 8.1e-25 86.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 KFL60853.1 - 0.12 12.6 0.0 6.2 7.1 0.0 3.1 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase UPF0139 PF03669.13 KFL60855.1 - 9.3e-08 31.8 0.1 1.2e-07 31.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DNA_pol_B PF00136.21 KFL60856.1 - 4.7e-101 338.8 0.0 7e-101 338.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 KFL60856.1 - 1.3e-16 60.8 9.4 1.3e-16 60.8 9.4 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.19 KFL60856.1 - 2.6e-15 56.4 0.0 3.6e-12 46.1 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 KFL60856.1 - 0.015 13.9 0.0 0.026 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) AA_permease PF00324.21 KFL60858.1 - 1.1e-131 439.8 40.7 1.3e-131 439.5 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFL60858.1 - 2.4e-36 125.5 45.3 2.9e-36 125.2 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFL60859.1 - 1.1e-122 410.1 35.3 1.3e-122 409.8 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFL60859.1 - 1.7e-31 109.5 39.6 2.1e-31 109.2 39.6 1.1 1 0 0 1 1 1 1 Amino acid permease DDE_Tnp_1_assoc PF13808.6 KFL60859.1 - 0.049 13.7 0.0 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 DDE_Tnp_1-associated AA_permease PF00324.21 KFL60860.1 - 1.2e-114 383.5 36.6 1.4e-114 383.4 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFL60860.1 - 5.2e-36 124.4 37.5 5.8e-36 124.2 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease Sulfate_transp PF00916.20 KFL60861.1 - 3.2e-88 296.0 9.6 4e-88 295.7 9.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFL60861.1 - 5.6e-08 32.4 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KFL60861.1 - 5e-06 26.9 10.5 4.4e-05 23.8 3.0 2.7 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily I_LWEQ PF01608.17 KFL60862.1 - 7.7e-57 191.8 8.0 7.7e-57 191.8 8.0 6.4 3 2 1 6 6 6 2 I/LWEQ domain ANTH PF07651.16 KFL60862.1 - 2.4e-08 33.3 0.0 2.4e-08 33.3 0.0 3.3 3 1 0 3 3 3 1 ANTH domain Med12 PF09497.10 KFL60863.1 - 2e-28 98.5 0.1 6.3e-28 96.9 0.1 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Kv2channel PF03521.14 KFL60863.1 - 0.0027 17.1 1.9 0.0042 16.5 1.9 1.2 1 0 0 1 1 1 1 Kv2 voltage-gated K+ channel Med12-LCEWAV PF12145.8 KFL60863.1 - 0.02 13.7 0.1 0.13 11.1 0.0 1.9 1 1 1 2 2 2 0 Eukaryotic Mediator 12 subunit domain Barttin PF15462.6 KFL60863.1 - 0.069 12.9 0.5 0.15 11.9 0.5 1.5 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) SAICAR_synt PF01259.18 KFL60865.1 - 1.5e-72 244.3 0.0 1.8e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase RRM_1 PF00076.22 KFL60866.1 - 2.3e-12 46.5 0.0 5.5e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF966 PF06136.13 KFL60866.1 - 1.4 8.5 27.3 1.7 8.2 27.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Totivirus_coat PF05518.11 KFL60866.1 - 5.9 4.8 11.6 7.3 4.5 11.6 1.0 1 0 0 1 1 1 0 Totivirus coat protein CMS1 PF14617.6 KFL60868.1 - 4.4e-51 173.7 0.1 4.8e-51 173.5 0.1 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KFL60868.1 - 5.9e-05 22.9 0.0 8.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_L22 PF00237.19 KFL60868.1 - 0.089 13.0 0.2 0.12 12.6 0.2 1.4 1 1 0 1 1 1 0 Ribosomal protein L22p/L17e CMS1 PF14617.6 KFL60869.1 - 3.3e-11 43.0 0.6 3.9e-11 42.8 0.6 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ATP-sulfurylase PF01747.17 KFL60872.1 - 1.8e-87 292.3 0.0 2.6e-87 291.8 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KFL60872.1 - 8.8e-58 194.7 0.0 1.4e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KFL60872.1 - 1.1e-17 64.1 0.0 2e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain ATP-sulfurylase PF01747.17 KFL60873.1 - 1.6e-87 292.4 0.0 2.1e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KFL60873.1 - 7.7e-58 194.8 0.0 1.2e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KFL60873.1 - 0.00067 19.4 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain ATP-sulfurylase PF01747.17 KFL60874.1 - 1.6e-87 292.4 0.0 2.1e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KFL60874.1 - 7.7e-58 194.8 0.0 1.2e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KFL60874.1 - 0.00067 19.4 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain ATP-sulfurylase PF01747.17 KFL60875.1 - 4.2e-71 238.8 0.0 5.5e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KFL60875.1 - 5e-58 195.5 0.0 7.6e-58 194.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 KFL60876.1 - 4.2e-71 238.8 0.0 5.5e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KFL60876.1 - 5e-58 195.5 0.0 7.6e-58 194.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 KFL60877.1 - 4.2e-71 238.8 0.0 5.5e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KFL60877.1 - 5e-58 195.5 0.0 7.6e-58 194.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PCI PF01399.27 KFL60878.1 - 1e-22 80.6 0.1 3.6e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KFL60878.1 - 1.8e-16 59.9 1.9 4.1e-16 58.8 1.9 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DASH_Dad1 PF08649.10 KFL60879.1 - 0.12 12.6 0.1 0.22 11.7 0.1 1.5 1 1 0 1 1 1 0 DASH complex subunit Dad1 DUF5313 PF17240.2 KFL60880.1 - 3.5 8.1 5.5 20 5.7 1.9 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5313) Ras PF00071.22 KFL60882.1 - 9.1e-45 152.2 0.0 1.1e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL60882.1 - 6e-22 78.1 0.0 7.6e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL60882.1 - 6.2e-10 38.8 0.0 7.6e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFL60882.1 - 5.1e-05 22.8 0.0 6.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFL60882.1 - 0.00086 18.8 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFL60882.1 - 0.0017 17.6 0.0 0.0052 16.0 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KFL60882.1 - 0.0051 16.9 0.0 0.0068 16.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFL60882.1 - 0.012 15.5 0.0 4.4 7.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KFL60882.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KFL60882.1 - 0.11 12.8 0.0 0.17 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 KFL60883.1 - 2.4e-34 118.3 0.0 2.8e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL60883.1 - 3.1e-12 46.8 0.0 5.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL60883.1 - 4.9e-05 22.9 0.0 6.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFL60883.1 - 0.059 12.7 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region EMG1 PF03587.14 KFL60885.1 - 4.2e-79 264.7 0.0 5.1e-79 264.5 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase UPF0506 PF11703.8 KFL60886.1 - 0.0074 16.6 5.1 0.012 16.0 5.1 1.3 1 0 0 1 1 1 1 UPF0506 Colipase-like PF15083.6 KFL60886.1 - 0.0079 16.3 2.4 0.011 15.8 2.4 1.2 1 0 0 1 1 1 1 Colipase-like DEC-1_N PF04625.13 KFL60886.1 - 0.0098 14.9 8.5 0.011 14.8 8.5 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region DUF5525 PF17663.1 KFL60886.1 - 0.012 13.8 8.5 0.014 13.5 8.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Conotoxin PF02950.17 KFL60886.1 - 0.029 15.4 2.2 0.051 14.6 2.2 1.4 1 1 0 1 1 1 0 Conotoxin Toxin_29 PF08116.11 KFL60886.1 - 0.048 13.7 3.2 0.083 12.9 3.2 1.3 1 0 0 1 1 1 0 PhTx neurotoxin family Conotoxin_I2 PF17557.2 KFL60886.1 - 0.052 13.7 9.1 0.091 12.9 9.1 1.3 1 0 0 1 1 1 0 I2-superfamily conotoxins Toxin_18 PF08087.11 KFL60886.1 - 0.35 10.9 5.2 0.74 9.9 5.2 1.5 1 0 0 1 1 1 0 Conotoxin O-superfamily XPG_I PF00867.18 KFL60887.1 - 3.5e-30 104.2 1.1 1.6e-29 102.1 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KFL60887.1 - 2.5e-19 69.6 0.2 8.9e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KFL60887.1 - 8.7e-05 23.1 0.7 0.00038 21.0 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.11 KFL60887.1 - 0.078 12.5 5.1 0.051 13.1 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) XPG_I PF00867.18 KFL60888.1 - 3.5e-30 104.2 1.1 1.6e-29 102.1 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KFL60888.1 - 2.5e-19 69.6 0.2 8.9e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KFL60888.1 - 8.7e-05 23.1 0.7 0.00038 21.0 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.11 KFL60888.1 - 0.078 12.5 5.1 0.051 13.1 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) ANAPC1 PF12859.7 KFL60890.1 - 1.6e-32 112.8 1.3 1.6e-32 112.8 1.3 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KFL60890.1 - 0.00021 21.6 9.4 0.0095 16.3 0.1 4.7 5 0 0 5 5 5 2 Proteasome/cyclosome repeat US22 PF02393.16 KFL60890.1 - 0.14 12.4 0.0 48 4.3 0.0 3.2 3 0 0 3 3 3 0 US22 like Fungal_trans_2 PF11951.8 KFL60892.1 - 6.6e-27 94.3 0.1 1.2e-26 93.5 0.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain HUN PF08729.10 KFL60893.1 - 1.9e-08 34.2 0.6 3.9e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Pkinase PF00069.25 KFL60896.1 - 1.5e-41 142.6 0.0 1.8e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL60896.1 - 6.6e-22 78.0 0.0 1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL60896.1 - 4.9e-05 22.3 0.0 7.1e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFL60896.1 - 0.031 13.6 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 KFL60896.1 - 0.065 12.3 0.0 0.091 11.8 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KFL60896.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFL60896.1 - 0.14 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DEAD_2 PF06733.15 KFL60897.1 - 1.5e-38 132.2 0.0 2e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 DEAD_2 AAA_22 PF13401.6 KFL60897.1 - 0.011 16.0 0.3 0.096 13.0 0.2 2.2 1 1 1 2 2 2 0 AAA domain PLDc PF00614.22 KFL60898.1 - 2.3e-17 62.4 0.4 4.5e-08 32.9 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KFL60898.1 - 3.7e-13 49.5 0.0 6.2e-07 29.4 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 KFL60898.1 - 7.2e-10 38.9 0.2 2.2e-09 37.3 0.2 1.9 1 0 0 1 1 1 1 PX domain UNC-50 PF05216.13 KFL60899.1 - 4e-76 255.5 7.3 5.4e-76 255.0 7.3 1.1 1 0 0 1 1 1 1 UNC-50 family FAD_binding_3 PF01494.19 KFL60900.1 - 7.3e-11 41.9 0.1 1.3e-09 37.8 0.0 2.4 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KFL60900.1 - 3.7e-07 30.3 0.0 7e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFL60900.1 - 1.1e-06 28.2 0.0 0.0013 18.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFL60900.1 - 9.7e-06 26.1 0.0 0.00072 20.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFL60900.1 - 0.0001 22.0 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFL60900.1 - 0.0066 15.6 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PQQ PF01011.21 KFL60900.1 - 0.0067 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 PQQ enzyme repeat HI0933_like PF03486.14 KFL60900.1 - 0.054 12.2 0.0 0.21 10.2 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 KFL60900.1 - 0.077 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 KFL60900.1 - 0.11 11.6 0.1 0.22 10.5 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KFL60900.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KFL60900.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TAS2R PF05296.13 KFL60901.1 - 0.04 13.0 1.1 0.065 12.3 1.1 1.2 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) MFS_1 PF07690.16 KFL60902.1 - 3.2e-33 115.1 24.7 5.3e-33 114.4 24.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFL60902.1 - 0.00048 19.5 3.1 0.00048 19.5 3.1 2.2 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 KFL60903.1 - 2.5e-18 66.1 38.0 2.5e-18 66.1 38.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFL60904.1 - 2.5e-18 66.1 38.0 2.5e-18 66.1 38.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SUIM_assoc PF16619.5 KFL60905.1 - 4.1 7.5 40.7 0.11 12.6 5.7 4.1 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Chitin_synth_1 PF01644.17 KFL60907.1 - 1.9e-73 245.8 0.0 2.7e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KFL60907.1 - 4.7e-30 103.4 0.0 8.9e-30 102.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFL60907.1 - 1.1e-17 63.9 0.0 2.4e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KFL60907.1 - 2.9e-05 24.1 14.6 0.00079 19.4 14.6 2.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Sugar_tr PF00083.24 KFL60911.1 - 4.4e-16 58.8 4.4 5.2e-16 58.5 4.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFL60911.1 - 1.4e-05 24.2 10.7 2e-05 23.7 10.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 KFL60911.1 - 0.0091 15.8 9.4 0.024 14.5 9.4 1.8 1 1 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 KFL60911.1 - 0.016 14.9 5.5 0.036 13.8 5.5 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper PT-VENN PF04829.13 KFL60911.1 - 0.15 12.2 0.8 0.15 12.2 0.8 1.9 2 1 0 2 2 2 0 Pre-toxin domain with VENN motif Gly-zipper_Omp PF13488.6 KFL60911.1 - 1.8 8.6 10.9 0.09 12.8 2.3 2.1 1 1 1 2 2 2 0 Glycine zipper Sugar_tr PF00083.24 KFL60912.1 - 1.9e-19 69.9 7.0 2.4e-19 69.6 7.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFL60912.1 - 8.7e-05 21.6 12.4 0.00012 21.2 12.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 KFL60913.1 - 7.1e-52 176.5 3.8 7.1e-52 176.5 3.8 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFL60913.1 - 1.5e-39 134.7 0.1 4.2e-39 133.2 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFL60913.1 - 9.3e-21 74.2 1.1 9.3e-21 74.2 1.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFL60913.1 - 4.2e-06 26.2 0.1 6.1e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFL60913.1 - 4.5e-06 26.0 0.1 0.064 12.4 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KFL60913.1 - 0.00047 19.5 0.9 0.0027 17.0 0.4 2.4 2 1 1 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.19 KFL60913.1 - 0.0033 16.7 1.7 0.096 12.0 0.1 3.0 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DAO PF01266.24 KFL60913.1 - 0.0046 16.6 6.3 0.27 10.8 1.9 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFL60913.1 - 0.0087 16.3 0.3 0.017 15.3 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFL60913.1 - 0.028 13.1 4.8 2.5 6.7 0.7 3.1 3 0 0 3 3 3 0 HI0933-like protein 3HCDH_N PF02737.18 KFL60913.1 - 0.1 12.5 1.1 0.3 10.9 1.1 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KFL60913.1 - 0.17 11.1 2.8 5.1 6.2 0.5 2.6 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.22 KFL60913.1 - 0.19 10.8 4.2 1.5 7.9 1.3 2.6 2 1 0 2 2 2 0 Glucose inhibited division protein A RNA_pol_N PF01194.17 KFL60914.1 - 3.5e-31 107.3 1.4 4e-31 107.1 1.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KFL60914.1 - 0.029 14.6 0.6 0.049 13.9 0.6 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) MFS_1 PF07690.16 KFL60915.1 - 2.1e-26 92.7 36.2 2.1e-26 92.7 36.2 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2254 PF10011.9 KFL60915.1 - 0.00061 18.7 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) Sarcolipin PF05366.11 KFL60915.1 - 0.039 13.7 0.1 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Sarcolipin Peptidase_C54 PF03416.19 KFL60917.1 - 7.4e-22 78.1 0.1 1.7e-21 76.9 0.0 1.5 2 0 0 2 2 2 1 Peptidase family C54 MGC-24 PF05283.11 KFL60917.1 - 0.093 13.2 3.8 0.13 12.7 3.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Sporozoite_P67 PF05642.11 KFL60917.1 - 5.9 4.8 7.8 7.2 4.6 7.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YccV-like PF08755.11 KFL60918.1 - 6.3e-21 74.7 0.6 2.8e-20 72.6 0.2 2.1 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KFL60918.1 - 7e-15 54.9 0.0 1.2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KFL60918.1 - 6.7e-06 25.9 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFL60918.1 - 0.00098 18.9 0.0 0.0026 17.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KFL60918.1 - 0.0026 18.2 0.1 0.0054 17.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A 23S_rRNA_IVP PF05635.11 KFL60918.1 - 0.041 14.2 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein SPX PF03105.19 KFL60919.1 - 4.5e-45 155.2 0.1 9.2e-45 154.2 0.1 1.5 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 KFL60919.1 - 8.5e-07 28.7 9.3 1.6e-06 27.9 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFL60919.1 - 5.4e-06 26.5 10.5 5.4e-06 26.5 10.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFL60919.1 - 1.4e-05 24.9 10.3 3.6e-05 23.6 10.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFL60919.1 - 2.3e-05 24.1 10.8 5.7e-05 22.9 10.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFL60919.1 - 0.00015 22.0 12.5 0.00036 20.8 12.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFL60919.1 - 0.00029 20.6 12.1 0.00069 19.4 12.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFL60919.1 - 0.0016 18.4 10.9 0.0041 17.1 10.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFL60919.1 - 0.0096 15.9 3.4 0.021 14.9 3.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFL60919.1 - 0.012 15.4 9.9 0.045 13.6 10.1 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFL60919.1 - 0.026 14.3 3.4 0.026 14.3 3.4 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TerY_C PF15616.6 KFL60919.1 - 0.03 14.4 0.6 0.057 13.5 0.6 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-rbx1 PF12678.7 KFL60919.1 - 0.41 11.0 9.8 1.4 9.3 9.8 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-P11 PF03854.14 KFL60919.1 - 0.46 10.2 8.2 12 5.7 8.5 2.3 1 1 1 2 2 2 0 P-11 zinc finger SPX PF03105.19 KFL60920.1 - 2e-29 103.7 0.1 3.1e-29 103.1 0.1 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 KFL60920.1 - 7.2e-07 29.0 9.3 1.4e-06 28.1 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFL60920.1 - 2.4e-06 27.6 10.5 4.6e-06 26.7 10.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFL60920.1 - 1.3e-05 25.1 10.3 3.1e-05 23.8 10.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFL60920.1 - 2.3e-05 24.2 10.8 4.9e-05 23.1 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFL60920.1 - 8.5e-05 22.8 11.9 0.00018 21.8 11.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFL60920.1 - 0.00027 20.7 12.1 0.0006 19.6 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFL60920.1 - 0.00087 19.3 10.1 0.002 18.1 10.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFL60920.1 - 0.0081 16.2 3.2 0.016 15.2 3.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFL60920.1 - 0.011 15.6 10.0 0.044 13.6 10.2 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFL60920.1 - 0.023 14.5 3.4 0.023 14.5 3.4 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TerY_C PF15616.6 KFL60920.1 - 0.048 13.8 0.6 0.1 12.7 0.6 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-P11 PF03854.14 KFL60920.1 - 0.28 10.9 8.1 8.6 6.1 8.4 2.4 1 1 1 2 2 2 0 P-11 zinc finger zf-rbx1 PF12678.7 KFL60920.1 - 0.43 10.9 10.0 1.3 9.3 10.0 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain UCH_C PF18031.1 KFL60921.1 - 0.036 14.0 1.4 0.094 12.6 1.4 1.7 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases Peptidase_C12 PF01088.21 KFL60922.1 - 4.5e-62 209.5 0.1 5.4e-62 209.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 I-set PF07679.16 KFL60924.1 - 0.0056 16.7 0.1 0.29 11.2 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin I-set domain DUF1918 PF08940.11 KFL60924.1 - 0.036 13.7 0.0 18 5.0 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1918) Cys_Met_Meta_PP PF01053.20 KFL60925.1 - 3.5e-18 65.3 0.0 8.9e-18 64.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme AAA_17 PF13207.6 KFL60928.1 - 3.7e-15 56.5 0.1 1.4e-14 54.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain HAD PF12710.7 KFL60928.1 - 7.3e-09 36.3 0.0 1.2e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SKI PF01202.22 KFL60928.1 - 0.018 15.2 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase KAP_NTPase PF07693.14 KFL60928.1 - 0.026 13.8 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 KFL60928.1 - 0.028 15.0 0.0 0.052 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFL60928.1 - 0.07 13.5 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KFL60928.1 - 0.13 11.4 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Oxysterol_BP PF01237.18 KFL60929.1 - 3.5e-43 147.9 0.0 7.7e-41 140.2 0.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein Oxysterol_BP PF01237.18 KFL60930.1 - 2.8e-45 154.8 0.0 5.9e-43 147.1 0.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein Oxysterol_BP PF01237.18 KFL60931.1 - 2.8e-45 154.8 0.0 5.9e-43 147.1 0.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein Oxysterol_BP PF01237.18 KFL60932.1 - 2.8e-45 154.8 0.0 5.9e-43 147.1 0.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein SMC_N PF02463.19 KFL60933.1 - 3e-09 36.7 0.0 6.3e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KFL60933.1 - 0.006 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Fez1 PF06818.15 KFL60933.1 - 2 8.8 30.1 0.13 12.7 14.8 3.1 1 1 1 3 3 3 0 Fez1 PspA_IM30 PF04012.12 KFL60934.1 - 0.034 13.7 12.0 0.045 13.3 12.0 1.1 1 0 0 1 1 1 0 PspA/IM30 family Spc7 PF08317.11 KFL60934.1 - 0.08 11.8 6.1 0.13 11.1 6.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 KFL60934.1 - 0.13 11.7 4.0 0.16 11.4 4.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 KFL60934.1 - 0.56 9.2 3.8 0.74 8.8 3.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KFL60934.1 - 7.8 5.8 9.9 11 5.3 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SCO1-SenC PF02630.14 KFL60937.1 - 1e-46 158.2 0.0 1.6e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KFL60937.1 - 0.0027 17.6 0.0 0.0057 16.6 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family FYTT PF07078.11 KFL60937.1 - 0.096 12.0 0.5 0.13 11.6 0.5 1.1 1 0 0 1 1 1 0 Forty-two-three protein Thioredoxin_8 PF13905.6 KFL60937.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like SCO1-SenC PF02630.14 KFL60938.1 - 2.3e-44 150.6 0.0 3.4e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KFL60938.1 - 0.0022 17.9 0.0 0.0043 17.0 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family FYTT PF07078.11 KFL60938.1 - 0.085 12.2 0.7 0.11 11.8 0.7 1.1 1 0 0 1 1 1 0 Forty-two-three protein Thioredoxin_8 PF13905.6 KFL60938.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like SLAC1 PF03595.17 KFL60939.1 - 4.9e-98 328.4 56.1 5.7e-98 328.2 56.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.17 KFL60940.1 - 3.3e-69 233.6 30.0 4e-69 233.3 30.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Caerin_1 PF07440.12 KFL60940.1 - 0.021 14.9 2.5 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Caerin 1 protein SLAC1 PF03595.17 KFL60941.1 - 3.3e-69 233.6 30.0 4e-69 233.3 30.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Caerin_1 PF07440.12 KFL60941.1 - 0.021 14.9 2.5 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Caerin 1 protein SLAC1 PF03595.17 KFL60942.1 - 2.1e-89 300.0 46.5 2.6e-89 299.7 46.5 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel Caerin_1 PF07440.12 KFL60942.1 - 4.2 7.6 6.2 15 5.8 1.1 2.9 3 0 0 3 3 3 0 Caerin 1 protein SLAC1 PF03595.17 KFL60943.1 - 4.4e-93 312.1 54.3 5e-93 311.9 54.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Caerin_1 PF07440.12 KFL60943.1 - 0.37 10.9 2.3 15 5.8 1.1 2.6 2 0 0 2 2 2 0 Caerin 1 protein Ion_trans_2 PF07885.16 KFL60945.1 - 3.1e-24 84.7 24.8 3.3e-14 52.6 7.5 3.2 3 1 0 3 3 3 2 Ion channel T6PP_N PF18572.1 KFL60945.1 - 0.052 13.4 1.4 0.1 12.4 1.4 1.4 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF2700 PF10912.8 KFL60945.1 - 0.7 9.9 4.9 0.18 11.8 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2700) GWT1 PF06423.12 KFL60945.1 - 3.4 7.8 5.5 20 5.3 1.6 2.7 2 1 0 2 2 2 0 GWT1 Ion_trans PF00520.31 KFL60945.1 - 4.3 6.5 16.8 1.4 8.1 2.3 2.9 2 1 1 3 3 3 0 Ion transport protein Ribosomal_L34e PF01199.18 KFL60948.1 - 0.032 14.5 0.4 0.054 13.8 0.1 1.5 2 0 0 2 2 2 0 Ribosomal protein L34e Glyoxal_oxid_N PF07250.11 KFL60949.1 - 1.3e-24 86.7 0.0 1.2e-23 83.6 0.0 2.3 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KFL60949.1 - 1.3e-21 76.7 0.0 2.3e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 KFL60949.1 - 0.016 15.1 0.5 0.25 11.4 0.0 3.3 4 0 0 4 4 4 0 Kelch motif WSC PF01822.19 KFL60950.1 - 5.7e-36 122.6 28.5 1.1e-18 67.2 10.7 2.3 2 0 0 2 2 2 2 WSC domain Antimicrobial22 PF16047.5 KFL60955.1 - 0.15 12.0 2.1 0.21 11.5 0.3 2.0 2 0 0 2 2 2 0 Frog antimicrobial peptide 6PGD PF00393.19 KFL60958.1 - 1e-127 425.5 0.0 1.2e-127 425.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFL60958.1 - 5.1e-45 153.5 0.0 7.5e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFL60958.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Esterase_phd PF10503.9 KFL60958.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase 6PGD PF00393.19 KFL60959.1 - 7.1e-128 426.0 0.0 8.3e-128 425.8 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFL60959.1 - 6.3e-30 104.4 0.0 9.5e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFL60959.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Esterase_phd PF10503.9 KFL60959.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase 6PGD PF00393.19 KFL60960.1 - 8.1e-75 251.9 0.0 1e-74 251.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFL60960.1 - 1.4e-50 171.5 0.0 2.1e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KFL60960.1 - 0.031 14.3 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Esterase_phd PF10503.9 KFL60960.1 - 0.092 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase NAD_binding_11 PF14833.6 KFL60960.1 - 0.097 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 6PGD PF00393.19 KFL60961.1 - 7.2e-75 252.0 0.0 9.1e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFL60961.1 - 2.6e-45 154.4 0.0 3.7e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Esterase_phd PF10503.9 KFL60961.1 - 0.087 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase NAD_binding_11 PF14833.6 KFL60961.1 - 0.091 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF3328 PF11807.8 KFL60965.1 - 2.8e-17 63.2 2.5 3.8e-17 62.8 2.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) AA_permease_2 PF13520.6 KFL60973.1 - 1.8e-58 198.4 43.3 2.4e-58 198.0 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFL60973.1 - 7.4e-21 74.3 38.8 1e-20 73.8 38.8 1.0 1 0 0 1 1 1 1 Amino acid permease Plasmod_dom_1 PF09715.10 KFL60973.1 - 0.13 12.3 1.1 0.59 10.2 1.1 2.2 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) FAD_binding_3 PF01494.19 KFL60974.1 - 1.6e-13 50.7 0.3 1.4e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFL60974.1 - 2.7e-05 23.9 1.9 0.0068 16.0 0.4 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFL60974.1 - 5.6e-05 22.4 0.1 0.0003 20.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KFL60974.1 - 9e-05 21.8 0.1 0.0002 20.7 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFL60974.1 - 0.04 12.6 0.3 0.063 12.0 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 KFL60974.1 - 0.086 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFL60974.1 - 0.16 11.2 0.2 0.63 9.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Imm_superinfect PF14373.6 KFL60975.1 - 0.0009 19.1 1.8 0.0018 18.1 1.8 1.5 1 0 0 1 1 1 1 Superinfection immunity protein zf-C2H2_2 PF12756.7 KFL60976.1 - 1.6e-35 121.5 20.6 1.6e-30 105.4 3.3 3.8 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFL60976.1 - 6.8e-11 42.2 14.7 2e-05 24.7 2.4 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFL60976.1 - 1.2e-08 35.0 13.1 1.7e-06 28.2 2.9 4.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type DUF2024 PF09630.10 KFL60976.1 - 0.011 15.6 3.9 0.067 13.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) Cytochrome_CBB3 PF13442.6 KFL60976.1 - 0.075 13.4 3.0 6.6 7.1 0.3 3.0 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome-c551 PF10643.9 KFL60976.1 - 0.08 12.5 0.3 9.7 5.7 0.0 2.2 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 zf-C2H2 PF00096.26 KFL60976.1 - 0.13 12.8 0.3 0.13 12.8 0.3 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type GOLD_2 PF13897.6 KFL60976.1 - 2.6 8.5 8.2 0.25 11.8 2.2 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking zf-C2H2_2 PF12756.7 KFL60977.1 - 1.1e-30 105.9 3.3 1.1e-30 105.9 3.3 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF2024 PF09630.10 KFL60977.1 - 0.0015 18.3 0.7 0.05 13.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2024) GOLD_2 PF13897.6 KFL60977.1 - 1.4 9.4 8.0 0.18 12.3 2.4 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking WD40 PF00400.32 KFL60982.1 - 2.4e-27 94.6 22.8 8.2e-09 36.0 0.5 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL60982.1 - 2e-07 31.2 1.7 0.047 14.0 0.1 3.6 2 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KFL60982.1 - 3.7e-06 26.1 0.8 2.1e-05 23.7 0.1 2.3 2 1 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KFL60982.1 - 5.7e-06 25.3 2.0 0.037 12.7 0.1 3.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFL60982.1 - 0.0029 16.6 0.1 6.6 5.6 0.0 3.7 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 KFL60982.1 - 0.013 15.3 2.0 0.19 11.5 0.2 3.3 2 1 1 3 3 3 0 TUP1-like enhancer of split Frtz PF11768.8 KFL60982.1 - 0.24 9.7 0.0 0.46 8.7 0.0 1.4 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 KFL60983.1 - 2.4e-27 94.6 22.8 8.2e-09 36.0 0.5 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL60983.1 - 2e-07 31.2 1.7 0.047 14.0 0.1 3.6 2 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KFL60983.1 - 3.7e-06 26.1 0.8 2.1e-05 23.7 0.1 2.3 2 1 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KFL60983.1 - 5.7e-06 25.3 2.0 0.037 12.7 0.1 3.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFL60983.1 - 0.0029 16.6 0.1 6.6 5.6 0.0 3.7 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 KFL60983.1 - 0.013 15.3 2.0 0.19 11.5 0.2 3.3 2 1 1 3 3 3 0 TUP1-like enhancer of split Frtz PF11768.8 KFL60983.1 - 0.24 9.7 0.0 0.46 8.7 0.0 1.4 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Leo1 PF04004.13 KFL60984.1 - 3.2e-29 101.9 0.8 3.2e-29 101.9 0.8 2.4 2 1 0 2 2 2 1 Leo1-like protein DTHCT PF08070.11 KFL60984.1 - 0.54 11.0 21.9 1.8 9.4 4.7 4.0 2 1 1 3 3 3 0 DTHCT (NUC029) region Nop14 PF04147.12 KFL60984.1 - 2.9 6.0 27.4 3.9 5.6 27.4 1.1 1 0 0 1 1 1 0 Nop14-like family Acetyltransf_1 PF00583.25 KFL60986.1 - 2e-12 47.4 0.4 2.3e-12 47.2 0.4 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFL60986.1 - 2.5e-11 43.6 0.0 2.5e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFL60986.1 - 5e-10 39.7 0.1 6.4e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFL60986.1 - 5.2e-09 35.9 0.1 5.7e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KFL60986.1 - 0.00023 20.9 0.1 0.00028 20.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFL60986.1 - 0.00048 20.2 0.0 0.00056 20.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFL60986.1 - 0.0082 16.3 0.2 0.016 15.3 0.1 1.5 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 KFL60986.1 - 0.033 13.9 0.2 0.036 13.8 0.2 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 KFL60986.1 - 0.16 12.1 0.0 0.17 12.1 0.0 1.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PP2C PF00481.21 KFL60987.1 - 2.4e-14 53.6 0.0 1.1e-13 51.4 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C YL1 PF05764.13 KFL60988.1 - 0.011 15.9 2.6 0.013 15.7 2.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KFL60988.1 - 0.04 12.2 0.5 0.044 12.1 0.5 1.1 1 0 0 1 1 1 0 CDC45-like protein UTP25 PF06862.12 KFL60989.1 - 1.3e-105 353.9 0.0 1.4e-105 353.8 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 JAB PF01398.21 KFL60991.1 - 6.8e-20 71.2 0.0 1.2e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFL60991.1 - 1.8e-18 67.0 0.2 3.3e-18 66.1 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 KFL60991.1 - 0.0001 22.4 0.0 0.00023 21.3 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) HECT PF00632.25 KFL60992.1 - 3.3e-98 328.9 0.0 4.6e-98 328.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFL60992.1 - 4.9e-33 112.9 31.6 9.7e-13 48.0 5.7 4.7 5 0 0 5 5 5 3 WW domain C2 PF00168.30 KFL60992.1 - 8.5e-20 71.0 0.0 2.2e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain HECT PF00632.25 KFL60993.1 - 1.3e-34 120.1 0.2 2.1e-34 119.4 0.2 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFL60993.1 - 1.5e-34 117.7 27.2 7.7e-13 48.3 5.7 4.3 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KFL60993.1 - 6.4e-20 71.4 0.0 1.6e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain WW PF00397.26 KFL60994.1 - 9.6e-35 118.4 27.2 6.8e-13 48.5 5.7 4.3 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KFL60994.1 - 5.6e-20 71.6 0.0 1.4e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain HECT PF00632.25 KFL60994.1 - 1.3e-18 67.6 0.2 1.9e-18 67.0 0.2 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Rhomboid PF01694.22 KFL60995.1 - 1.4e-22 80.4 8.9 2.5e-22 79.5 6.7 2.0 2 0 0 2 2 2 1 Rhomboid family Rhomboid PF01694.22 KFL60996.1 - 5.3e-15 55.7 6.8 1.5e-14 54.3 5.0 2.0 2 0 0 2 2 2 1 Rhomboid family Rhomboid PF01694.22 KFL60997.1 - 4.8e-15 55.9 6.8 1.4e-14 54.4 5.0 2.0 2 0 0 2 2 2 1 Rhomboid family Rhomboid PF01694.22 KFL60998.1 - 0.0019 18.2 0.1 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 Rhomboid family DUF2157 PF09925.9 KFL60998.1 - 0.095 12.5 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Rhomboid PF01694.22 KFL60999.1 - 0.0019 18.2 0.1 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 Rhomboid family DUF2157 PF09925.9 KFL60999.1 - 0.095 12.5 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Rhomboid PF01694.22 KFL61000.1 - 0.0017 18.4 0.1 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 Rhomboid family DUF2157 PF09925.9 KFL61000.1 - 0.083 12.7 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Rhomboid PF01694.22 KFL61001.1 - 0.0017 18.4 0.1 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 Rhomboid family DUF2157 PF09925.9 KFL61001.1 - 0.083 12.7 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) PEMT PF04191.13 KFL61002.1 - 1.9e-28 99.0 6.2 4.7e-28 97.7 4.8 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase HAD PF12710.7 KFL61006.1 - 8.1e-16 59.0 0.0 1.1e-15 58.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KFL61006.1 - 0.00037 20.1 0.0 0.00047 19.8 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 KFL61007.1 - 8.1e-16 59.0 0.0 1.1e-15 58.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KFL61007.1 - 0.00037 20.1 0.0 0.00047 19.8 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 KFL61008.1 - 3.7e-19 69.9 0.0 4.4e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KFL61008.1 - 6.1e-05 22.6 0.0 0.00043 19.9 0.0 1.9 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HECT PF00632.25 KFL61009.1 - 2.5e-53 181.6 0.0 3.2e-52 177.9 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) HECT PF00632.25 KFL61010.1 - 5.6e-34 118.0 0.0 7.8e-33 114.3 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) PBP1_TM PF14812.6 KFL61011.1 - 0.0025 18.1 3.5 0.0031 17.8 3.5 1.2 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KFL61011.1 - 0.17 11.5 6.4 0.2 11.3 6.4 1.1 1 0 0 1 1 1 0 FAM176 family PAP2 PF01569.21 KFL61012.1 - 2.5e-30 105.0 0.4 2.5e-30 105.0 0.4 2.1 1 1 1 2 2 2 2 PAP2 superfamily PAP2_3 PF14378.6 KFL61012.1 - 0.024 14.4 8.2 0.012 15.3 5.0 2.2 1 1 1 2 2 2 0 PAP2 superfamily DUF2418 PF10332.9 KFL61012.1 - 0.13 12.8 1.0 1.9 9.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2418) HEAT_EZ PF13513.6 KFL61013.1 - 2.1e-19 69.6 2.6 1.1e-05 25.7 0.0 9.5 9 2 2 11 11 11 3 HEAT-like repeat HEAT PF02985.22 KFL61013.1 - 1.1e-18 65.7 4.3 0.00048 20.2 0.1 9.3 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 KFL61013.1 - 1.6e-17 63.7 1.3 0.00037 20.8 0.0 6.9 6 1 1 7 7 7 4 HEAT repeats IFRD PF05004.13 KFL61013.1 - 6.8e-11 41.8 3.0 0.00086 18.5 0.1 4.6 2 1 2 5 5 5 2 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 KFL61013.1 - 5e-07 30.2 0.0 1.7 9.3 0.0 6.1 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFL61013.1 - 9.9e-07 28.9 0.6 1.4 8.9 0.0 4.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KFL61013.1 - 3.2e-06 26.5 0.2 4.2e-05 22.9 0.0 2.8 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal ParcG PF10274.9 KFL61013.1 - 0.00077 19.6 0.1 0.047 13.8 0.1 2.9 2 0 0 2 2 2 1 Parkin co-regulated protein CLASP_N PF12348.8 KFL61013.1 - 0.001 18.7 1.2 0.12 12.0 0.0 4.0 5 1 0 5 5 5 1 CLASP N terminal RIX1 PF08167.12 KFL61013.1 - 0.0067 16.2 0.1 0.27 11.0 0.0 3.4 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 KFL61013.1 - 0.0073 16.5 0.5 2.4 8.4 0.0 4.2 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 KFL61013.1 - 0.011 15.6 0.1 0.055 13.4 0.1 2.3 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central Ecm29 PF13001.7 KFL61013.1 - 0.016 14.0 0.4 0.27 9.9 0.0 2.9 2 1 0 3 3 3 0 Proteasome stabiliser Arm PF00514.23 KFL61013.1 - 0.022 14.8 1.3 73 3.6 0.0 5.3 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KFL61013.1 - 0.042 12.4 0.7 8.9 4.7 0.0 3.1 3 1 0 3 3 3 0 Adaptin N terminal region Tti2 PF10521.9 KFL61013.1 - 0.086 12.4 0.0 2.4 7.6 0.0 3.0 3 1 1 4 4 4 0 Tti2 family Cohesin_HEAT PF12765.7 KFL61013.1 - 0.092 13.1 0.0 0.54 10.6 0.0 2.5 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 KFL61014.1 - 6.6e-20 71.2 1.1 7.7e-06 26.3 0.0 8.3 7 2 3 10 10 10 4 HEAT-like repeat HEAT_2 PF13646.6 KFL61014.1 - 4.7e-16 58.9 0.5 0.00024 21.4 0.0 5.7 5 2 1 6 6 5 4 HEAT repeats HEAT PF02985.22 KFL61014.1 - 3.3e-15 54.9 5.4 0.00032 20.7 0.1 8.3 8 0 0 8 8 8 4 HEAT repeat IFRD PF05004.13 KFL61014.1 - 2.1e-10 40.2 1.3 0.00059 19.0 0.1 3.8 1 1 3 4 4 4 2 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 KFL61014.1 - 4.9e-06 25.9 0.2 2.7e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 KFL61014.1 - 6.2e-06 26.7 0.0 1.1 9.8 0.0 5.3 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 KFL61014.1 - 0.00011 22.0 0.2 0.00011 22.0 0.2 3.2 4 0 0 4 4 3 1 Importin-beta N-terminal domain Cnd1 PF12717.7 KFL61014.1 - 0.00013 22.0 0.6 0.94 9.5 0.0 4.0 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 KFL61014.1 - 0.0005 20.2 0.1 0.03 14.4 0.1 2.6 2 0 0 2 2 2 1 Parkin co-regulated protein RTP1_C1 PF10363.9 KFL61014.1 - 0.0048 17.1 0.2 1.6 9.0 0.0 3.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KFL61014.1 - 0.0048 16.9 0.5 50 4.1 0.0 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Ecm29 PF13001.7 KFL61014.1 - 0.0058 15.4 0.5 0.2 10.3 0.0 3.1 2 1 1 4 4 4 1 Proteasome stabiliser CLASP_N PF12348.8 KFL61014.1 - 0.0062 16.1 1.1 0.074 12.6 0.0 3.3 4 1 0 4 4 4 1 CLASP N terminal UNC45-central PF11701.8 KFL61014.1 - 0.0066 16.4 0.1 0.034 14.1 0.1 2.3 1 1 0 1 1 1 1 Myosin-binding striated muscle assembly central RIX1 PF08167.12 KFL61014.1 - 0.02 14.7 0.0 0.17 11.6 0.0 2.6 3 0 0 3 3 2 0 rRNA processing/ribosome biogenesis Tti2 PF10521.9 KFL61014.1 - 0.049 13.2 0.0 2 7.9 0.0 3.0 2 1 1 3 3 3 0 Tti2 family Cohesin_HEAT PF12765.7 KFL61014.1 - 0.066 13.5 0.0 0.37 11.1 0.0 2.4 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion NUC173 PF08161.12 KFL61014.1 - 0.12 12.0 0.3 16 5.1 0.0 4.0 3 1 1 4 4 4 0 NUC173 domain DUF2433 PF10360.9 KFL61015.1 - 8.6e-49 164.8 0.0 1.5e-48 164.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) TFIIA PF03153.13 KFL61015.1 - 0.46 10.4 11.3 0.66 9.9 11.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2433 PF10360.9 KFL61016.1 - 8.6e-49 164.8 0.0 1.5e-48 164.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) TFIIA PF03153.13 KFL61016.1 - 0.46 10.4 11.3 0.66 9.9 11.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TRAUB PF08164.12 KFL61018.1 - 2.3e-24 85.7 0.0 7.5e-24 84.1 0.0 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Abhydrolase_3 PF07859.13 KFL61018.1 - 3.2e-08 33.7 0.0 3.7e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Zn_clus PF00172.18 KFL61021.1 - 0.0004 20.4 7.6 0.0004 20.4 7.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hva1_TUDOR PF11160.8 KFL61022.1 - 6.4e-12 45.4 0.1 7e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Ank_2 PF12796.7 KFL61023.1 - 0.00023 21.7 0.0 0.00056 20.4 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFL61023.1 - 0.00079 19.8 0.0 0.026 14.9 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KFL61023.1 - 0.0025 18.4 0.0 0.35 11.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFL61023.1 - 0.0043 17.4 0.0 0.021 15.3 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KFL61023.1 - 0.0054 17.0 0.0 0.0096 16.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) FtsJ PF01728.19 KFL61024.1 - 4.9e-64 215.7 0.0 6.2e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase LUC7 PF03194.15 KFL61026.1 - 2.5e-73 246.9 0.1 3e-73 246.6 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus TelA PF05816.11 KFL61026.1 - 0.0042 16.2 0.5 0.0068 15.5 0.5 1.3 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DASH_Duo1 PF08651.10 KFL61026.1 - 0.062 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF3584 PF12128.8 KFL61026.1 - 0.063 10.8 0.1 0.081 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2130 PF09903.9 KFL61026.1 - 0.086 12.1 0.3 0.15 11.3 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) T4SS PF07996.11 KFL61026.1 - 0.12 12.8 0.1 0.4 11.1 0.0 1.8 1 1 1 2 2 2 0 Type IV secretion system proteins PP_kinase_N PF13089.6 KFL61026.1 - 0.12 12.6 0.1 0.61 10.4 0.0 1.9 1 1 1 2 2 2 0 Polyphosphate kinase N-terminal domain GRP PF07172.11 KFL61026.1 - 0.16 12.7 18.4 0.26 12.0 18.4 1.3 1 0 0 1 1 1 0 Glycine rich protein family MCPsignal PF00015.21 KFL61026.1 - 0.19 11.5 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain XhlA PF10779.9 KFL61026.1 - 0.21 11.8 2.5 0.35 11.1 0.6 2.0 2 0 0 2 2 2 0 Haemolysin XhlA Gpi16 PF04113.14 KFL61027.1 - 1.1e-166 555.6 0.0 1.3e-166 555.4 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component ERG4_ERG24 PF01222.17 KFL61028.1 - 5.3e-148 493.3 17.6 6e-148 493.2 17.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ERG4_ERG24 PF01222.17 KFL61029.1 - 1.3e-121 406.4 11.9 1.4e-121 406.3 11.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Peptidase_M43 PF05572.13 KFL61030.1 - 2e-16 60.2 0.2 3.1e-16 59.7 0.2 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 KFL61030.1 - 6.6e-07 29.9 0.9 5.4e-06 26.9 0.9 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFL61030.1 - 4.4e-06 27.0 2.6 9.4e-06 25.9 2.6 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFL61030.1 - 0.00027 20.7 2.0 0.0019 17.8 2.0 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFL61030.1 - 0.0031 17.4 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 KFL61030.1 - 0.024 13.6 0.2 0.031 13.2 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.24 KFL61030.1 - 0.043 13.4 0.1 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) DUF4953 PF16313.5 KFL61030.1 - 0.093 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_2 PF13574.6 KFL61030.1 - 0.12 12.3 3.0 0.15 11.9 3.0 1.3 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 KFL61030.1 - 0.14 11.8 2.6 0.17 11.4 0.5 2.0 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M7 PF02031.16 KFL61030.1 - 0.25 11.5 3.3 0.18 12.0 0.6 2.0 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family KCH PF16944.5 KFL61031.1 - 2.3e-12 47.2 0.5 2.9e-12 46.9 0.5 1.1 1 0 0 1 1 1 1 Fungal potassium channel Tim17 PF02466.19 KFL61033.1 - 2e-32 111.9 8.4 2.5e-32 111.6 8.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Tim17 PF02466.19 KFL61034.1 - 1.8e-22 79.8 0.5 2.2e-22 79.5 0.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Tim17 PF02466.19 KFL61035.1 - 1.8e-22 79.8 0.5 2.2e-22 79.5 0.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cerato-platanin PF07249.12 KFL61036.1 - 5.6e-44 149.0 0.3 6.7e-44 148.8 0.3 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 KFL61036.1 - 0.013 15.3 0.2 0.02 14.7 0.2 1.5 1 1 0 1 1 1 0 Barwin family Peptidase_M24 PF00557.24 KFL61038.1 - 1.5e-25 90.1 0.0 1.7e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KFL61039.1 - 8e-38 128.9 0.1 1.3e-37 128.3 0.1 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.24 KFL61039.1 - 4.1e-10 39.7 0.1 2.4e-09 37.2 0.0 2.2 2 1 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KFL61039.1 - 0.02 15.5 0.0 0.047 14.3 0.0 1.7 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain Pyridox_ox_2 PF12900.7 KFL61040.1 - 6.5e-32 110.5 0.0 1.1e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.25 KFL61041.1 - 4.2e-45 154.2 0.0 6.5e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61041.1 - 2.3e-23 82.8 0.0 3.1e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFL61041.1 - 3e-06 26.8 0.0 4.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFL61041.1 - 0.00018 20.4 0.0 0.00027 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL61041.1 - 0.0037 17.2 1.9 0.011 15.7 0.2 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL61041.1 - 0.019 14.4 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFL61041.1 - 0.039 12.9 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFL61041.1 - 0.24 10.4 0.1 0.33 9.9 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 KFL61042.1 - 4.2e-45 154.2 0.0 6.5e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61042.1 - 2.3e-23 82.8 0.0 3.1e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFL61042.1 - 3e-06 26.8 0.0 4.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFL61042.1 - 0.00018 20.4 0.0 0.00027 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFL61042.1 - 0.0037 17.2 1.9 0.011 15.7 0.2 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL61042.1 - 0.019 14.4 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFL61042.1 - 0.039 12.9 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFL61042.1 - 0.24 10.4 0.1 0.33 9.9 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L33 PF00471.20 KFL61043.1 - 1.1e-05 25.8 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 FYVE PF01363.21 KFL61045.1 - 2.4e-16 59.6 1.3 4e-16 58.9 1.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger VHS PF00790.19 KFL61045.1 - 2e-07 31.0 0.9 4.7e-06 26.5 0.0 2.6 2 0 0 2 2 2 1 VHS domain UIM PF02809.20 KFL61045.1 - 5e-07 29.2 10.5 0.00099 18.9 1.9 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 KFL61045.1 - 2e-05 24.8 0.0 5.5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 GAT domain FYVE_2 PF02318.16 KFL61045.1 - 0.051 13.8 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger OrfB_Zn_ribbon PF07282.11 KFL61045.1 - 0.9 9.5 4.9 1.1 9.2 3.6 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Fer4_2 PF12797.7 KFL61045.1 - 2.1 8.6 4.3 1.5 9.0 0.2 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Herpes_UL73 PF03554.13 KFL61046.1 - 0.68 10.0 4.4 0.94 9.5 4.4 1.2 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein K_trans PF02705.16 KFL61047.1 - 3.8e-168 560.3 23.3 4.6e-168 560.0 23.3 1.0 1 0 0 1 1 1 1 K+ potassium transporter KH_1 PF00013.29 KFL61048.1 - 2.3e-67 222.8 3.2 9.1e-12 44.6 0.2 9.8 9 1 0 9 9 9 7 KH domain KH_2 PF07650.17 KFL61048.1 - 1.1e-08 34.7 5.5 0.0018 18.1 0.0 5.6 5 1 0 5 5 5 2 KH domain KH_4 PF13083.6 KFL61048.1 - 0.0011 18.8 0.4 24 4.9 0.0 4.8 5 0 0 5 5 5 1 KH domain BMC PF00936.19 KFL61048.1 - 0.02 14.9 0.4 0.25 11.3 0.2 2.5 2 0 0 2 2 2 0 BMC domain KH_5 PF13184.6 KFL61048.1 - 0.1 12.7 2.0 28 4.9 0.3 4.2 4 0 0 4 4 4 0 NusA-like KH domain UCH_1 PF13423.6 KFL61049.1 - 4.2e-97 325.6 0.4 5.6e-97 325.2 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KFL61049.1 - 0.00018 22.1 0.0 0.00051 20.6 0.0 1.8 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 KFL61049.1 - 0.001 18.6 0.0 0.0051 16.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MSC PF09402.10 KFL61051.1 - 1.3e-26 93.9 0.5 1.6e-26 93.6 0.5 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain MSC PF09402.10 KFL61052.1 - 7e-57 193.4 0.0 1.1e-56 192.7 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KFL61052.1 - 2.3e-16 59.2 0.1 4.3e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain tRNA-synt_1b PF00579.25 KFL61053.1 - 1.4e-63 215.0 0.0 1.9e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RNA_polI_A14 PF08203.11 KFL61055.1 - 0.04 14.6 0.2 1.2 9.9 0.1 2.1 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 DUF5399 PF17377.2 KFL61056.1 - 0.056 13.3 0.0 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5399) Kinesin PF00225.23 KFL61058.1 - 8.9e-36 123.5 0.1 1.2e-35 123.0 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain SAM_PNT PF02198.16 KFL61058.1 - 0.041 13.8 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Malic_M PF03949.15 KFL61059.1 - 2.3e-92 308.9 0.0 3e-92 308.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFL61059.1 - 2.9e-47 160.8 0.0 5e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Band_7 PF01145.25 KFL61060.1 - 3.1e-11 43.6 0.0 3.1e-11 43.6 0.0 2.5 2 1 1 3 3 3 1 SPFH domain / Band 7 family Band_7 PF01145.25 KFL61061.1 - 3.4e-16 59.8 0.0 3.4e-16 59.8 0.0 2.1 2 1 0 2 2 2 1 SPFH domain / Band 7 family Sugar_tr PF00083.24 KFL61062.1 - 4e-34 118.2 11.3 4.4e-34 118.1 11.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter EBP PF05241.12 KFL61062.1 - 0.077 12.5 5.3 0.064 12.7 3.7 1.6 1 1 1 2 2 2 0 Emopamil binding protein DUF5423 PF17461.2 KFL61062.1 - 0.16 10.8 0.1 0.27 10.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Sugar_tr PF00083.24 KFL61063.1 - 2.3e-07 30.1 0.3 2.7e-07 29.8 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFL61063.1 - 0.0012 17.8 0.0 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF456 PF04306.13 KFL61063.1 - 0.065 13.5 0.6 0.086 13.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF4781 PF16013.5 KFL61065.1 - 0.13 11.1 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) p450 PF00067.22 KFL61066.1 - 2.1e-63 214.7 0.0 3.3e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KFL61066.1 - 6.5e-27 94.6 0.0 1.1e-26 93.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFL61066.1 - 2.7e-21 76.3 0.0 6.2e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFL61066.1 - 1.5e-11 44.9 0.0 3.6e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFL61066.1 - 0.0012 19.1 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.12 KFL61066.1 - 0.085 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain p450 PF00067.22 KFL61067.1 - 3.3e-59 200.9 0.1 4.9e-59 200.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KFL61067.1 - 6.1e-27 94.6 0.0 9.6e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFL61067.1 - 2.5e-21 76.4 0.0 5.7e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFL61067.1 - 1.4e-11 45.0 0.0 3.3e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFL61067.1 - 0.0011 19.2 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.12 KFL61067.1 - 0.078 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain p450 PF00067.22 KFL61068.1 - 1.6e-53 182.1 0.0 2.4e-53 181.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KFL61068.1 - 5.7e-27 94.7 0.0 8.9e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFL61068.1 - 2.7e-21 76.3 0.0 5.3e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFL61068.1 - 1.3e-11 45.1 0.0 3.1e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFL61068.1 - 0.001 19.3 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.12 KFL61068.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain p450 PF00067.22 KFL61069.1 - 1.2e-63 215.5 0.0 1.8e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.25 KFL61069.1 - 1.8e-21 76.8 0.0 4.1e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KFL61069.1 - 6e-07 29.3 0.0 2.6e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_5 PF12724.7 KFL61069.1 - 0.00094 19.4 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain FAD_binding_1 PF00667.20 KFL61070.1 - 4.2e-27 95.2 0.0 6.5e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.22 KFL61070.1 - 1.2e-26 93.5 0.1 1.8e-26 92.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.25 KFL61070.1 - 2.3e-21 76.5 0.0 4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFL61070.1 - 1.1e-11 45.4 0.0 2.4e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFL61070.1 - 0.00084 19.6 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.12 KFL61070.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain FAD_binding_1 PF00667.20 KFL61071.1 - 4.2e-27 95.2 0.0 6.5e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.22 KFL61071.1 - 1.2e-26 93.5 0.1 1.8e-26 92.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.25 KFL61071.1 - 2.3e-21 76.5 0.0 4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFL61071.1 - 1.1e-11 45.4 0.0 2.4e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFL61071.1 - 0.00084 19.6 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.12 KFL61071.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain FAD_binding_1 PF00667.20 KFL61072.1 - 4.2e-27 95.2 0.0 6.5e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.22 KFL61072.1 - 1.2e-26 93.5 0.1 1.8e-26 92.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.25 KFL61072.1 - 2.3e-21 76.5 0.0 4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFL61072.1 - 1.1e-11 45.4 0.0 2.4e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFL61072.1 - 0.00084 19.6 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.12 KFL61072.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain p450 PF00067.22 KFL61073.1 - 1.9e-59 201.6 0.1 2.5e-59 201.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.25 KFL61073.1 - 1.7e-21 77.0 0.0 3.6e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KFL61073.1 - 5.4e-07 29.4 0.0 2.3e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_5 PF12724.7 KFL61073.1 - 0.00085 19.6 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain CX9C PF16860.5 KFL61074.1 - 0.0009 19.2 0.7 0.0014 18.6 0.7 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 KFL61074.1 - 0.0021 17.7 2.6 0.66 9.7 0.7 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 KFL61074.1 - 0.085 13.0 2.6 0.69 10.1 2.3 2.1 1 1 1 2 2 2 0 CHCH domain CX9C PF16860.5 KFL61075.1 - 0.00071 19.5 0.8 0.00095 19.1 0.8 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 KFL61075.1 - 0.00095 18.8 1.7 0.55 10.0 0.3 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 KFL61075.1 - 0.043 14.0 2.6 0.32 11.2 2.2 2.0 1 1 1 2 2 2 0 CHCH domain XRN_M PF17846.1 KFL61077.1 - 1.4e-153 512.1 0.1 3.2e-153 510.9 0.1 1.5 1 1 0 1 1 1 1 Xrn1 helical domain Myc_N PF01056.18 KFL61077.1 - 0.3 10.9 3.2 0.47 10.3 3.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region AWS PF17907.1 KFL61080.1 - 0.089 12.8 0.4 0.16 12.0 0.4 1.4 1 0 0 1 1 1 0 AWS domain DUF4932 PF16286.5 KFL61081.1 - 0.048 12.9 0.1 0.051 12.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4932) UQ_con PF00179.26 KFL61082.1 - 2.6e-34 117.8 0.0 2.9e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFL61082.1 - 3.5e-07 30.0 0.0 4.3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFL61082.1 - 0.018 14.9 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KFL61082.1 - 0.099 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain TPR_14 PF13428.6 KFL61083.1 - 0.1 13.5 6.8 1.7 9.6 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFL61084.1 - 0.086 13.7 6.8 1.7 9.7 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFL61085.1 - 0.085 13.7 7.0 1.6 9.8 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SPX PF03105.19 KFL61086.1 - 3.9 7.3 7.7 6.7 6.5 7.7 1.3 1 1 0 1 1 1 0 SPX domain ChAPs PF09295.10 KFL61087.1 - 6e-66 223.1 0.0 9e-66 222.5 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_1 PF00515.28 KFL61087.1 - 0.00011 21.8 0.2 4.3 7.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFL61087.1 - 0.00019 21.3 0.3 0.54 10.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFL61087.1 - 0.00085 19.9 0.3 0.4 11.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFL61087.1 - 0.0014 18.8 0.2 0.36 11.0 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat CDC45 PF02724.14 KFL61087.1 - 0.0039 15.6 4.9 0.0045 15.3 4.9 1.1 1 0 0 1 1 1 1 CDC45-like protein TPR_12 PF13424.6 KFL61087.1 - 0.022 15.0 0.7 0.55 10.5 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Nop14 PF04147.12 KFL61087.1 - 0.12 10.6 10.8 0.15 10.3 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.6 KFL61087.1 - 0.13 12.7 9.7 0.11 12.9 7.5 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 KFL61087.1 - 0.25 11.0 12.1 0.4 10.4 12.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KFL61087.1 - 0.26 10.6 11.5 0.52 9.6 11.5 1.5 1 0 0 1 1 1 0 NOA36 protein ANAPC3 PF12895.7 KFL61087.1 - 0.56 10.5 3.3 1 9.6 0.2 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 XAP5 PF04921.14 KFL61087.1 - 0.72 9.6 6.6 0.71 9.7 5.3 1.6 2 0 0 2 2 2 0 XAP5, circadian clock regulator RRN3 PF05327.11 KFL61087.1 - 1.6 7.1 7.4 2.4 6.6 7.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ChAPs PF09295.10 KFL61088.1 - 4.2e-66 223.6 0.1 7.7e-66 222.7 0.0 1.5 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_1 PF00515.28 KFL61088.1 - 9e-05 22.1 0.2 3.9 7.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFL61088.1 - 0.00014 21.7 0.3 0.5 10.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFL61088.1 - 0.00058 20.5 0.2 0.36 11.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFL61088.1 - 0.0012 19.0 0.2 0.33 11.1 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat CDC45 PF02724.14 KFL61088.1 - 0.0051 15.2 5.9 0.0059 15.0 5.9 1.1 1 0 0 1 1 1 1 CDC45-like protein TPR_12 PF13424.6 KFL61088.1 - 0.019 15.2 0.7 0.5 10.7 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFL61088.1 - 0.083 13.0 0.6 19 5.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PBP1_TM PF14812.6 KFL61088.1 - 0.095 13.1 9.7 0.095 13.1 7.5 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 KFL61088.1 - 0.098 10.9 11.1 0.12 10.5 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family ANAPC3 PF12895.7 KFL61088.1 - 0.46 10.7 3.3 0.91 9.8 0.2 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SDA1 PF05285.12 KFL61088.1 - 0.5 9.7 12.4 0.66 9.3 12.4 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 KFL61088.1 - 1.1 7.7 7.4 1.7 7.1 7.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ChAPs PF09295.10 KFL61089.1 - 5.1e-66 223.3 0.0 7.6e-66 222.7 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_1 PF00515.28 KFL61089.1 - 8.9e-05 22.2 0.2 3.9 7.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFL61089.1 - 0.00014 21.7 0.3 0.49 10.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFL61089.1 - 0.00058 20.5 0.2 0.36 11.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFL61089.1 - 0.0012 19.0 0.2 0.33 11.1 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat CDC45 PF02724.14 KFL61089.1 - 0.0058 15.0 5.6 0.0067 14.8 5.6 1.1 1 0 0 1 1 1 1 CDC45-like protein TPR_12 PF13424.6 KFL61089.1 - 0.019 15.2 0.7 0.5 10.7 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFL61089.1 - 0.082 13.0 0.6 19 5.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PBP1_TM PF14812.6 KFL61089.1 - 0.094 13.1 9.5 0.095 13.1 7.5 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 KFL61089.1 - 0.1 10.8 10.8 0.13 10.5 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 KFL61089.1 - 0.22 11.2 12.1 0.35 10.6 12.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ANAPC3 PF12895.7 KFL61089.1 - 0.46 10.7 3.3 0.91 9.8 0.2 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 XAP5 PF04921.14 KFL61089.1 - 0.49 10.2 6.3 0.62 9.8 5.3 1.6 2 0 0 2 2 2 0 XAP5, circadian clock regulator RRN3 PF05327.11 KFL61089.1 - 1.2 7.6 7.1 1.8 7.0 7.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-T_C PF15511.6 KFL61090.1 - 1.1e-08 35.1 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KFL61090.1 - 3.7e-05 24.1 0.1 4.2e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KFL61090.1 - 0.00012 22.2 0.1 0.00017 21.7 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFL61090.1 - 0.00049 20.4 0.1 0.00066 20.0 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFL61090.1 - 0.00053 20.2 0.1 0.0011 19.2 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFL61090.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFL61090.1 - 0.052 13.6 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated HIGH_NTase1_ass PF16581.5 KFL61090.1 - 0.15 12.0 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region zf-C2H2 PF00096.26 KFL61091.1 - 2.9e-10 40.0 14.4 0.00012 22.3 1.4 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFL61091.1 - 8.9e-07 29.2 11.2 0.022 15.6 1.1 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 KFL61091.1 - 0.4 11.0 6.8 0.7 10.2 1.5 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KFL61091.1 - 0.78 10.3 11.0 10 6.8 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger double domain Methyltransf_28 PF02636.17 KFL61092.1 - 3.3e-63 213.8 0.0 4.2e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_28 PF02636.17 KFL61093.1 - 2.9e-48 164.8 0.0 4e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MR_MLE_N PF02746.16 KFL61095.1 - 9.1e-07 29.1 0.1 1.1e-06 28.8 0.1 1.1 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE_C PF13378.6 KFL61096.1 - 1.8e-36 125.8 0.0 2.2e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFL61096.1 - 0.0057 15.8 0.0 0.011 14.9 0.0 1.4 1 1 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Pterin_bind PF00809.22 KFL61097.1 - 5.8e-80 268.5 0.2 7e-80 268.2 0.2 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KFL61097.1 - 3.1e-16 59.9 0.3 7.8e-16 58.6 0.3 1.7 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Pterin_bind PF00809.22 KFL61098.1 - 2.4e-80 269.7 0.2 2.8e-80 269.5 0.2 1.0 1 0 0 1 1 1 1 Pterin binding enzyme AMP-binding PF00501.28 KFL61100.1 - 1.8e-67 227.8 0.0 2.2e-49 168.2 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KFL61100.1 - 0.00039 21.3 0.1 0.0011 19.9 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MIF4G PF02854.19 KFL61101.1 - 6.9e-53 179.4 0.0 1.1e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KFL61101.1 - 7.6e-25 86.9 2.1 2.1e-24 85.5 2.1 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MIF4G PF02854.19 KFL61102.1 - 6.5e-53 179.5 0.0 1e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KFL61102.1 - 2e-24 85.5 2.1 2e-24 85.5 2.1 2.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 MIF4G PF02854.19 KFL61103.1 - 4.7e-49 166.9 0.0 7.6e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KFL61103.1 - 6.4e-25 87.1 2.1 1.8e-24 85.7 2.1 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MIF4G PF02854.19 KFL61104.1 - 4.2e-49 167.1 0.0 6.8e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KFL61104.1 - 5.8e-25 87.3 2.1 1.7e-24 85.8 2.1 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MIF4G PF02854.19 KFL61105.1 - 3.9e-49 167.2 0.0 6.3e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KFL61105.1 - 5.4e-25 87.4 2.1 1.6e-24 85.9 2.1 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MIF4G PF02854.19 KFL61106.1 - 3.4e-49 167.4 0.0 5.5e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KFL61106.1 - 4.9e-25 87.5 2.1 1.4e-24 86.0 2.1 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Glyco_hydro_18 PF00704.28 KFL61108.1 - 7.7e-46 157.3 0.5 1.4e-45 156.4 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KFL61108.1 - 7.8e-11 41.9 0.0 4.1e-08 33.2 0.0 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KFL61108.1 - 1.8e-07 31.5 9.4 1.8e-07 31.5 9.4 4.1 4 1 0 4 4 4 1 Chitin recognition protein MFS_1 PF07690.16 KFL61109.1 - 1.2e-10 40.8 58.2 3.7e-07 29.4 19.0 2.7 2 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL61109.1 - 0.001 18.0 12.0 0.001 18.0 12.0 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter UxuA PF03786.13 KFL61109.1 - 0.059 12.2 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) MFS_1 PF07690.16 KFL61110.1 - 2.5e-05 23.4 49.0 0.0032 16.4 49.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL61110.1 - 0.00079 18.4 12.0 0.00079 18.4 12.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFL61111.1 - 3.9e-08 32.6 46.8 0.00022 20.3 27.6 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL61111.1 - 0.00014 20.9 26.7 0.00074 18.5 12.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFL61112.1 - 0.00011 21.3 28.3 0.00023 20.2 28.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL61112.1 - 0.00028 19.9 12.0 0.00052 19.0 12.0 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TANGO2 PF05742.12 KFL61113.1 - 1.2e-74 251.6 0.0 1.4e-74 251.4 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Pkinase PF00069.25 KFL61114.1 - 4.4e-26 91.8 0.0 6.4e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61114.1 - 1.2e-06 28.0 0.0 2.3e-06 27.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KFL61114.1 - 0.00082 18.8 0.1 0.0012 18.2 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFL61114.1 - 0.0074 16.2 0.0 0.017 15.1 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFL61114.1 - 0.19 11.0 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KFL61116.1 - 4.6e-10 39.3 1.2 4.8e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61116.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LCD1 PF09798.9 KFL61116.1 - 0.02 13.5 0.5 0.019 13.5 0.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein CDC45 PF02724.14 KFL61116.1 - 0.32 9.2 5.7 0.37 9.0 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein MCM_bind PF09739.9 KFL61116.1 - 0.44 8.9 9.1 0.52 8.7 9.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Ndc1_Nup PF09531.10 KFL61116.1 - 1.2 7.7 4.5 1.3 7.6 4.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NPR3 PF03666.13 KFL61116.1 - 1.4 7.6 7.0 1.6 7.5 7.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KFL61116.1 - 1.5 7.5 8.9 1.6 7.4 8.9 1.0 1 0 0 1 1 1 0 Presenilin DUF1168 PF06658.12 KFL61116.1 - 2.2 8.1 16.6 3.2 7.6 16.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) U79_P34 PF03064.16 KFL61116.1 - 3.2 7.0 15.0 5.1 6.4 15.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pkinase PF00069.25 KFL61117.1 - 3.1e-44 151.3 0.0 3.5e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61117.1 - 2.4e-15 56.6 0.0 3.3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFL61117.1 - 0.014 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KFL61117.1 - 0.022 13.7 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFL61117.1 - 0.059 12.7 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFL61117.1 - 0.099 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Med27 PF11571.8 KFL61118.1 - 6e-21 74.6 0.5 1e-20 73.9 0.5 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 HSP70 PF00012.20 KFL61119.1 - 1.6e-253 842.4 14.6 1.8e-253 842.2 14.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL61119.1 - 5.1e-13 48.5 2.5 5.1e-13 48.5 2.5 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KFL61119.1 - 0.0001 22.1 0.0 0.00026 20.8 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 KFL61119.1 - 0.0058 15.9 3.6 0.088 12.0 0.2 3.0 2 1 1 3 3 3 1 StbA protein DUF1464 PF07318.12 KFL61119.1 - 0.058 12.5 1.2 0.54 9.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1464) SMBP PF16785.5 KFL61119.1 - 0.095 12.9 3.8 0.11 12.7 1.1 2.3 2 0 0 2 2 2 0 Small metal-binding protein Scaffolding_pro PF11418.8 KFL61119.1 - 0.1 13.2 0.9 0.24 12.0 0.9 1.6 1 0 0 1 1 1 0 Phi29 scaffolding protein Histone_HNS PF00816.21 KFL61119.1 - 7.8 7.4 9.6 39 5.2 3.8 3.3 3 0 0 3 3 3 0 H-NS histone family DEAD PF00270.29 KFL61120.1 - 4.1e-18 65.7 0.0 7.6e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFL61120.1 - 1.3e-06 28.7 0.0 4.6e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFL61120.1 - 3.2e-05 24.0 0.0 5.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFL61120.1 - 0.17 12.2 0.0 0.5 10.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain DSHCT PF08148.12 KFL61121.1 - 4.1e-52 176.1 0.5 8.6e-52 175.1 0.5 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 KFL61121.1 - 2.8e-17 63.5 0.9 2.3e-16 60.5 0.9 2.2 1 1 0 1 1 1 1 rRNA-processing arch domain RRM_1 PF00076.22 KFL61123.1 - 6.2e-08 32.3 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFL61123.1 - 1.7e-05 24.7 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFL61123.1 - 0.00077 19.3 0.0 0.0042 16.9 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif Zn_clus PF00172.18 KFL61124.1 - 5.8e-05 23.1 17.1 9.8e-05 22.4 17.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glucosamine_iso PF01182.20 KFL61126.1 - 3.1e-15 56.7 0.0 5.4e-15 55.9 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hep_59 PF07052.11 KFL61128.1 - 1.6e-12 48.1 0.1 1.6e-12 48.1 0.1 2.2 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 ELFV_dehydrog PF00208.21 KFL61130.1 - 1.5e-47 162.4 0.0 2.3e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KFL61130.1 - 0.0084 13.7 0.0 0.016 12.8 0.0 1.3 2 0 0 2 2 2 1 Bacterial NAD-glutamate dehydrogenase SLBP_RNA_bind PF15247.6 KFL61135.1 - 0.095 12.8 0.3 18 5.6 0.0 2.2 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain Peptidase_M36 PF02128.15 KFL61136.1 - 6.3e-156 519.2 5.0 7.5e-156 518.9 5.0 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 KFL61136.1 - 0.034 14.0 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain ALMT PF11744.8 KFL61139.1 - 0.042 12.7 0.0 0.042 12.7 0.0 2.1 2 1 1 3 3 3 0 Aluminium activated malate transporter YajC PF02699.15 KFL61139.1 - 0.048 13.5 0.2 0.17 11.8 0.2 1.9 1 0 0 1 1 1 0 Preprotein translocase subunit ArAE_2_N PF10337.9 KFL61139.1 - 0.063 12.3 0.1 0.063 12.3 0.1 1.7 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal KIP1 PF07765.12 KFL61139.1 - 0.32 11.1 1.6 3.2 7.9 0.1 2.2 1 1 1 2 2 2 0 KIP1-like protein ALMT PF11744.8 KFL61140.1 - 0.042 12.7 0.0 0.042 12.7 0.0 2.1 2 1 1 3 3 3 0 Aluminium activated malate transporter YajC PF02699.15 KFL61140.1 - 0.048 13.5 0.2 0.17 11.8 0.2 1.9 1 0 0 1 1 1 0 Preprotein translocase subunit ArAE_2_N PF10337.9 KFL61140.1 - 0.063 12.3 0.1 0.063 12.3 0.1 1.7 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal KIP1 PF07765.12 KFL61140.1 - 0.32 11.1 1.6 3.2 7.9 0.1 2.2 1 1 1 2 2 2 0 KIP1-like protein ALMT PF11744.8 KFL61141.1 - 0.042 12.7 0.0 0.042 12.7 0.0 2.1 2 1 1 3 3 3 0 Aluminium activated malate transporter YajC PF02699.15 KFL61141.1 - 0.048 13.5 0.2 0.17 11.8 0.2 1.9 1 0 0 1 1 1 0 Preprotein translocase subunit ArAE_2_N PF10337.9 KFL61141.1 - 0.063 12.3 0.1 0.063 12.3 0.1 1.7 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal KIP1 PF07765.12 KFL61141.1 - 0.32 11.1 1.6 3.2 7.9 0.1 2.2 1 1 1 2 2 2 0 KIP1-like protein RrnaAD PF00398.20 KFL61142.1 - 8.9e-27 93.8 0.0 1.4e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase RRM_1 PF00076.22 KFL61143.1 - 1.6e-19 69.4 0.2 2.4e-15 56.1 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFL61143.1 - 2.6e-05 24.2 0.0 0.00058 19.9 0.1 2.7 2 1 0 2 2 2 1 RNA recognition motif MCRS_N PF13325.6 KFL61143.1 - 0.6 10.1 2.7 1.2 9.1 2.7 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein LOH1CR12 PF10158.9 KFL61143.1 - 0.69 9.9 5.0 1.9 8.5 5.0 1.7 1 0 0 1 1 1 0 Tumour suppressor protein Ammonium_transp PF00909.21 KFL61144.1 - 2.3e-89 299.9 17.5 2.6e-89 299.7 17.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family VTC PF09359.10 KFL61146.1 - 1.9e-100 335.8 0.3 3e-100 335.2 0.3 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 KFL61146.1 - 3.8e-13 50.1 6.9 6.3e-06 26.4 0.0 3.4 2 1 1 3 3 3 3 SPX domain VTC PF09359.10 KFL61147.1 - 1.9e-100 335.8 0.3 2.9e-100 335.2 0.3 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 KFL61147.1 - 6.9e-15 55.8 5.5 6.2e-06 26.4 0.0 3.4 2 1 1 3 3 3 3 SPX domain VTC PF09359.10 KFL61148.1 - 4.7e-68 229.6 0.3 6.2e-68 229.2 0.3 1.2 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KFL61148.1 - 1.4e-11 44.7 3.6 1.4e-11 44.7 3.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MCM PF00493.23 KFL61149.1 - 9.1e-103 342.2 0.0 1.4e-102 341.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KFL61149.1 - 1.5e-28 99.0 2.3 1.5e-28 99.0 2.3 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_OB PF17207.3 KFL61149.1 - 1.5e-26 92.7 0.5 3e-26 91.7 0.5 1.5 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 KFL61149.1 - 2.6e-06 27.0 0.0 0.00014 21.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFL61149.1 - 8.1e-06 25.9 0.3 5.2e-05 23.3 0.0 2.5 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFL61149.1 - 0.00042 20.2 0.0 0.0055 16.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFL61149.1 - 0.074 12.8 0.1 3.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain PIG-S PF10510.9 KFL61149.1 - 0.37 9.6 2.9 0.78 8.5 1.1 1.9 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein AAA_32 PF13654.6 KFL61149.1 - 0.95 8.2 6.2 0.5 9.1 0.5 2.2 2 0 0 2 2 2 0 AAA domain MCM_N PF14551.6 KFL61150.1 - 4.7e-18 65.7 0.0 7.8e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 MCM N-terminal domain NitrOD1 PF18549.1 KFL61150.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 Ribosomal_L16 PF00252.18 KFL61151.1 - 1.4e-33 115.7 0.2 2e-33 115.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ank_2 PF12796.7 KFL61154.1 - 6.2e-09 36.3 0.0 0.0026 18.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFL61154.1 - 8.3e-07 29.2 0.2 0.29 11.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat vWA-TerF-like PF10138.9 KFL61154.1 - 8.9e-07 29.2 0.0 1.7e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus Ank_5 PF13857.6 KFL61154.1 - 8.9e-05 22.7 0.4 0.5 10.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFL61154.1 - 0.00015 22.3 0.1 1.5 9.5 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeats (many copies) SseC PF04888.12 KFL61154.1 - 0.00035 20.3 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Zn_clus PF00172.18 KFL61154.1 - 0.0016 18.6 1.0 0.0029 17.7 1.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_3 PF13606.6 KFL61154.1 - 0.0095 16.4 0.0 7.6 7.5 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat CobS PF02654.15 KFL61154.1 - 0.05 13.8 1.7 0.33 11.1 0.3 2.3 2 0 0 2 2 2 0 Cobalamin-5-phosphate synthase VWA_2 PF13519.6 KFL61154.1 - 0.11 13.1 0.0 0.41 11.3 0.0 2.1 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF3040 PF11239.8 KFL61154.1 - 0.21 11.9 0.9 0.68 10.2 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) LSM PF01423.22 KFL61155.1 - 4.2e-17 61.6 0.0 5.3e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFL61155.1 - 0.0043 17.2 0.0 0.0056 16.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 KFL61156.1 - 0.00049 19.7 0.0 0.00065 19.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain SelK_SelG PF10961.8 KFL61156.1 - 0.078 13.6 7.3 0.11 13.2 7.3 1.2 1 0 0 1 1 1 0 Selenoprotein SelK_SelG CRAL_TRIO PF00650.20 KFL61158.1 - 4.1e-36 124.1 0.0 5.1e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFL61158.1 - 0.0027 17.9 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 KFL61158.1 - 0.07 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) CRAL_TRIO PF00650.20 KFL61159.1 - 8e-29 100.4 0.0 1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFL61159.1 - 0.0019 18.4 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 KFL61159.1 - 0.05 13.8 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) CRAL_TRIO PF00650.20 KFL61160.1 - 8e-29 100.4 0.0 1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFL61160.1 - 0.0019 18.4 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 KFL61160.1 - 0.05 13.8 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) CRAL_TRIO PF00650.20 KFL61161.1 - 8e-29 100.4 0.0 1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFL61161.1 - 0.0019 18.4 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 KFL61161.1 - 0.05 13.8 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) CRAL_TRIO PF00650.20 KFL61162.1 - 8e-29 100.4 0.0 1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFL61162.1 - 0.0019 18.4 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 KFL61162.1 - 0.05 13.8 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) CRAL_TRIO PF00650.20 KFL61163.1 - 8e-29 100.4 0.0 1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFL61163.1 - 0.0019 18.4 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 KFL61163.1 - 0.05 13.8 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) CRAL_TRIO PF00650.20 KFL61164.1 - 8e-29 100.4 0.0 1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFL61164.1 - 0.0019 18.4 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 KFL61164.1 - 0.05 13.8 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) MBOAT PF03062.19 KFL61165.1 - 3.7e-45 154.8 15.5 4.3e-34 118.4 7.8 2.3 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family IGF2_C PF08365.11 KFL61166.1 - 0.053 13.5 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide Mon1 PF03164.14 KFL61167.1 - 2.2e-107 359.6 0.0 2.5e-107 359.5 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 DEAD PF00270.29 KFL61168.1 - 2.9e-22 79.3 0.0 7.2e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFL61168.1 - 1.3e-21 77.0 0.4 1.9e-17 63.6 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RQC PF09382.10 KFL61168.1 - 3.2e-14 52.7 0.0 7.4e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 KFL61168.1 - 5e-14 52.8 11.6 5.3e-14 52.7 8.9 2.4 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 KFL61168.1 - 1.5e-06 28.3 0.0 3.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KFL61168.1 - 0.0076 15.0 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain KH_1 PF00013.29 KFL61169.1 - 1.8e-43 146.2 4.0 1e-17 63.7 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFL61169.1 - 1.8e-11 43.7 2.0 0.011 15.5 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFL61169.1 - 1.2e-05 25.1 0.3 0.78 9.7 0.1 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 KFL61169.1 - 0.00012 22.0 0.0 0.019 15.0 0.0 2.4 2 0 0 2 2 2 1 KH-like RNA-binding domain KH_5 PF13184.6 KFL61169.1 - 0.00038 20.5 7.9 0.21 11.7 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain Pol_alpha_B_N PF08418.10 KFL61169.1 - 0.016 15.2 0.4 0.026 14.5 0.4 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal AA_permease_2 PF13520.6 KFL61170.1 - 6.4e-20 71.4 14.9 8.2e-20 71.0 14.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFL61171.1 - 2.9e-23 82.4 6.4 3.2e-23 82.3 6.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFL61171.1 - 1.1e-08 34.1 4.9 1.2e-08 34.0 4.9 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_oprn_chp PF09534.10 KFL61171.1 - 0.11 12.2 3.6 0.19 11.5 3.5 1.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Defb50 PF17546.2 KFL61173.1 - 0.08 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Beta defensin 50 Ribosomal_S19 PF00203.21 KFL61174.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S19 Methyltransf_23 PF13489.6 KFL61175.1 - 1.5e-09 37.9 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain HAT PF02184.16 KFL61175.1 - 0.18 11.8 0.7 19 5.3 0.0 3.3 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat PUB PF09409.10 KFL61175.1 - 0.21 11.5 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 PUB domain Methyltransf_23 PF13489.6 KFL61176.1 - 1.5e-09 37.9 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain HAT PF02184.16 KFL61176.1 - 0.18 11.8 0.7 19 5.3 0.0 3.3 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat PUB PF09409.10 KFL61176.1 - 0.21 11.5 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 PUB domain Methyltransf_23 PF13489.6 KFL61177.1 - 1.5e-09 37.9 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain HAT PF02184.16 KFL61177.1 - 0.18 11.8 0.7 19 5.3 0.0 3.3 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat PUB PF09409.10 KFL61177.1 - 0.21 11.5 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 PUB domain DUF3591 PF12157.8 KFL61178.1 - 2.5e-186 619.6 0.5 3.5e-186 619.2 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KFL61178.1 - 0.005 16.9 0.7 0.0087 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KFL61178.1 - 0.013 15.3 3.2 0.031 14.1 3.2 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3591 PF12157.8 KFL61179.1 - 2.4e-186 619.7 0.5 3.1e-186 619.3 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) NPL PF17800.1 KFL61180.1 - 1.7e-29 102.4 4.0 1.7e-29 102.4 4.0 2.8 2 2 0 2 2 2 1 Nucleoplasmin-like domain Utp14 PF04615.13 KFL61180.1 - 0.007 15.0 32.9 0.0095 14.6 32.9 1.2 1 0 0 1 1 1 1 Utp14 protein FKBP_C PF00254.28 KFL61180.1 - 0.012 15.9 0.0 0.065 13.6 0.0 2.2 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase PRCC PF10253.9 KFL61180.1 - 0.18 12.5 17.6 0.019 15.7 7.5 2.5 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting SurA_N PF09312.11 KFL61180.1 - 0.31 11.1 2.7 0.25 11.4 1.0 1.7 2 0 0 2 2 2 0 SurA N-terminal domain FKBP_C PF00254.28 KFL61181.1 - 4.5e-31 107.0 0.1 2.1e-30 104.9 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KFL61181.1 - 2e-21 76.5 7.0 2e-21 76.5 7.0 2.9 2 2 0 2 2 2 1 Nucleoplasmin-like domain Utp14 PF04615.13 KFL61181.1 - 0.013 14.1 33.4 0.018 13.7 33.4 1.3 1 0 0 1 1 1 0 Utp14 protein SurA_N PF09312.11 KFL61181.1 - 0.23 11.6 2.5 0.21 11.7 1.1 1.7 2 0 0 2 2 2 0 SurA N-terminal domain PRCC PF10253.9 KFL61181.1 - 0.68 10.7 19.7 0.074 13.8 9.4 2.4 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting NPL PF17800.1 KFL61182.1 - 1.4e-21 77.0 7.0 1.4e-21 77.0 7.0 2.9 2 2 0 2 2 2 1 Nucleoplasmin-like domain Utp14 PF04615.13 KFL61182.1 - 0.0071 15.0 33.0 0.0095 14.6 33.0 1.3 1 0 0 1 1 1 1 Utp14 protein FKBP_C PF00254.28 KFL61182.1 - 0.0082 16.4 0.0 0.05 13.9 0.0 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase SurA_N PF09312.11 KFL61182.1 - 0.16 12.1 2.4 0.18 11.9 1.1 1.7 2 0 0 2 2 2 0 SurA N-terminal domain PRCC PF10253.9 KFL61182.1 - 0.37 11.5 19.6 0.043 14.6 9.1 2.4 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting PPP1R35_C PF15503.6 KFL61182.1 - 5.4 6.8 6.9 0.87 9.4 1.7 1.9 1 1 1 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus DUF4246 PF14033.6 KFL61183.1 - 7.4e-05 22.0 0.1 9.1e-05 21.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) WD40 PF00400.32 KFL61188.1 - 9.8e-31 105.3 29.3 2.9e-07 31.1 1.9 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL61188.1 - 1.4e-16 60.5 0.1 0.0001 22.5 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KFL61188.1 - 0.03 12.7 0.0 0.13 10.6 0.0 1.9 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_S8 PF00082.22 KFL61190.1 - 1.3e-34 119.8 15.9 2.1e-34 119.1 15.9 1.3 1 0 0 1 1 1 1 Subtilase family DUF4843 PF16132.5 KFL61191.1 - 0.0039 16.8 0.1 0.014 14.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4843) dCache_2 PF08269.11 KFL61191.1 - 0.046 12.9 0.9 0.14 11.3 0.9 1.8 1 0 0 1 1 1 0 Cache domain Med30 PF11315.8 KFL61191.1 - 0.16 12.2 2.1 0.89 9.7 0.2 3.0 4 0 0 4 4 4 0 Mediator complex subunit 30 PEP-utilisers_N PF05524.13 KFL61191.1 - 0.25 11.5 2.2 0.73 10.0 0.2 2.7 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Radical_SAM PF04055.21 KFL61191.1 - 0.39 11.1 2.1 3.5 8.0 0.0 3.0 2 1 0 2 2 2 0 Radical SAM superfamily Prominin PF05478.11 KFL61191.1 - 0.64 7.9 2.9 0.58 8.0 1.1 1.7 2 0 0 2 2 2 0 Prominin YtxH PF12732.7 KFL61191.1 - 1.2 9.8 3.6 17 6.0 0.2 3.6 3 0 0 3 3 3 0 YtxH-like protein Uso1_p115_C PF04871.13 KFL61191.1 - 5.7 7.3 10.9 0.22 11.9 1.4 2.8 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMEM208_SND2 PF05620.11 KFL61192.1 - 3.4e-54 183.1 0.0 3.8e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Anillin PF08174.11 KFL61193.1 - 5.4e-09 36.6 0.9 1.3e-08 35.3 0.0 2.2 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.29 KFL61193.1 - 1.7e-07 31.7 0.0 5.5e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 KFL61194.1 - 5.3e-09 36.6 0.9 1.3e-08 35.4 0.0 2.2 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.29 KFL61194.1 - 1.7e-07 31.7 0.0 5.4e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 PH domain PseudoU_synth_1 PF01416.20 KFL61195.1 - 1.1e-10 41.9 0.0 2.1e-08 34.6 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase ATP_bind_2 PF03668.15 KFL61195.1 - 0.024 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family TFIIE_alpha PF02002.17 KFL61196.1 - 6.1e-08 32.5 0.1 1.4e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 TFIIE alpha subunit TEX19 PF15553.6 KFL61196.1 - 8.4 6.3 7.4 1.1 9.2 1.6 2.3 2 0 0 2 2 2 0 Testis-expressed protein 19 TEX19 PF15553.6 KFL61197.1 - 7.9 6.4 7.6 1.2 9.1 1.8 2.3 2 0 0 2 2 2 0 Testis-expressed protein 19 TrkH PF02386.16 KFL61198.1 - 2e-20 72.7 0.1 8.6e-17 60.7 0.0 2.1 2 0 0 2 2 2 2 Cation transport protein TrkH PF02386.16 KFL61199.1 - 3.6e-108 362.2 2.8 4.1e-108 362.0 2.8 1.0 1 0 0 1 1 1 1 Cation transport protein DUF3517 PF12030.8 KFL61201.1 - 3.9e-91 305.5 1.2 5.7e-91 304.9 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 KFL61201.1 - 2.1e-41 142.1 0.0 3.3e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFL61201.1 - 9.1e-23 81.3 0.0 1.7e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFL61201.1 - 0.04 13.4 0.1 0.09 12.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ADD_ATRX PF17981.1 KFL61201.1 - 0.09 12.7 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Cysteine Rich ADD domain eIF-5_eIF-2B PF01873.17 KFL61204.1 - 8.1e-35 119.2 0.0 1.4e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KFL61204.1 - 1.5e-21 76.3 0.4 1.5e-21 76.3 0.4 2.5 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon PcfK PF14058.6 KFL61204.1 - 0.2 12.0 0.0 0.2 12.0 0.0 3.0 3 0 0 3 3 3 0 PcfK-like protein eIF-5_eIF-2B PF01873.17 KFL61205.1 - 3.4e-39 133.3 0.0 5.6e-39 132.6 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 PcfK PF14058.6 KFL61205.1 - 0.067 13.5 5.3 0.19 12.0 0.0 2.4 2 0 0 2 2 2 0 PcfK-like protein BUD22 PF09073.10 KFL61205.1 - 1.3 8.3 17.8 1.8 7.9 17.8 1.1 1 0 0 1 1 1 0 BUD22 eIF-5_eIF-2B PF01873.17 KFL61206.1 - 5.7e-35 119.7 0.0 9.4e-35 119.0 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 PcfK PF14058.6 KFL61206.1 - 0.058 13.7 5.3 0.17 12.1 0.0 2.4 2 0 0 2 2 2 0 PcfK-like protein BUD22 PF09073.10 KFL61206.1 - 1.2 8.4 17.8 1.5 8.0 17.8 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 KFL61208.1 - 4.5e-74 249.3 16.6 5.5e-74 249.0 16.6 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 KFL61208.1 - 0.043 13.7 15.0 0.059 13.2 15.0 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing DUF4636 PF15468.6 KFL61208.1 - 0.46 10.1 3.8 0.66 9.6 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) SDA1 PF05285.12 KFL61208.1 - 0.58 9.5 18.8 0.66 9.4 18.8 1.1 1 0 0 1 1 1 0 SDA1 PA26 PF04636.13 KFL61208.1 - 1.3 7.8 3.9 1.6 7.6 3.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Phostensin_N PF13916.6 KFL61208.1 - 3.7 8.0 11.9 9.5 6.6 7.0 2.4 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Roughex PF06020.11 KFL61208.1 - 4.7 6.2 14.9 6.2 5.8 14.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Hid1 PF12722.7 KFL61208.1 - 5 5.1 6.2 5.5 5.0 6.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 KFL61208.1 - 7 5.3 6.8 8.2 5.1 6.8 1.1 1 0 0 1 1 1 0 Presenilin Cwf_Cwc_15 PF04889.12 KFL61209.1 - 1.1e-45 156.3 14.0 1.4e-45 156.0 14.0 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Takusan PF04822.13 KFL61209.1 - 0.51 10.2 4.3 1 9.3 4.3 1.4 1 0 0 1 1 1 0 Takusan DUF4636 PF15468.6 KFL61209.1 - 1.2 8.8 4.9 1.8 8.2 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Nucleo_P87 PF07267.11 KFL61209.1 - 2.9 6.6 4.4 2.9 6.7 4.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 KFL61209.1 - 5.7 5.1 9.3 6.1 5.0 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MFAP1 PF06991.11 KFL61209.1 - 7.2 6.4 16.7 9.1 6.1 16.2 1.4 1 1 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing CLN3 PF02487.17 KFL61211.1 - 2.8e-150 500.8 2.0 2.8e-150 500.8 2.0 1.5 2 0 0 2 2 2 1 CLN3 protein Abhydrolase_3 PF07859.13 KFL61211.1 - 1.1e-32 113.6 0.0 3.2e-22 79.4 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFL61211.1 - 0.21 10.4 0.0 0.38 9.5 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase DUF2046 PF09755.9 KFL61212.1 - 0.023 14.0 1.1 0.035 13.3 0.4 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Sec62 PF03839.16 KFL61213.1 - 8.4e-71 237.9 0.4 8.4e-71 237.9 0.4 2.1 2 0 0 2 2 2 1 Translocation protein Sec62 PAT1 PF09770.9 KFL61213.1 - 0.16 10.2 20.8 0.21 9.9 20.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EPL1 PF10513.9 KFL61213.1 - 0.18 12.1 2.8 0.26 11.7 2.8 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Ribosomal_L20 PF00453.18 KFL61213.1 - 0.25 11.4 4.0 0.52 10.4 0.4 2.6 3 1 0 3 3 3 0 Ribosomal protein L20 TFIIA PF03153.13 KFL61213.1 - 0.3 11.0 25.1 0.41 10.6 25.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1125 PF06563.11 KFL61214.1 - 0.19 11.7 0.2 18 5.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1125) Cupin_1 PF00190.22 KFL61215.1 - 9.8e-30 103.2 0.0 5.6e-17 61.7 0.0 2.3 2 1 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KFL61215.1 - 4.1e-18 64.9 0.3 6.2e-11 41.9 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KFL61215.1 - 7.8e-06 25.5 0.1 0.0065 16.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AAA_10 PF12846.7 KFL61216.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ClpB_D2-small PF10431.9 KFL61216.1 - 0.02 14.9 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 KFL61216.1 - 0.036 14.5 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 KFL61216.1 - 0.059 12.5 0.1 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 KFL61216.1 - 0.15 11.6 0.1 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_10 PF12846.7 KFL61217.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ClpB_D2-small PF10431.9 KFL61217.1 - 0.02 14.9 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 KFL61217.1 - 0.036 14.5 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 KFL61217.1 - 0.059 12.5 0.1 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 KFL61217.1 - 0.15 11.6 0.1 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region SNAP PF14938.6 KFL61218.1 - 4.6e-112 374.0 19.7 5.2e-112 373.9 19.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KFL61218.1 - 2.1e-08 34.3 8.0 0.00072 19.8 0.2 3.8 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFL61218.1 - 2.8e-05 23.9 12.1 0.68 10.2 0.1 6.2 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFL61218.1 - 0.0035 17.2 4.2 21 5.4 0.0 5.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFL61218.1 - 0.036 14.3 15.8 1.3 9.4 0.1 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat NigD_N PF12667.7 KFL61218.1 - 0.096 12.8 0.0 2.9 8.1 0.0 2.8 2 0 0 2 2 2 0 NigD-like N-terminal OB domain NSF PF02071.20 KFL61218.1 - 0.16 12.8 0.4 0.16 12.8 0.4 6.1 6 0 0 6 6 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_16 PF13432.6 KFL61218.1 - 0.18 12.5 14.9 3.9 8.2 2.7 4.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFL61218.1 - 0.2 11.5 15.2 3.1 7.8 0.9 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFL61218.1 - 0.24 12.1 15.9 4.8 8.0 0.1 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat CBP PF12192.8 KFL61218.1 - 0.29 11.3 0.1 0.29 11.3 0.1 2.1 2 1 0 2 2 2 0 Fungal calcium binding protein MIT PF04212.18 KFL61218.1 - 0.44 10.7 7.6 17 5.6 0.2 4.7 2 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain SNAP PF14938.6 KFL61219.1 - 4.7e-80 269.0 18.2 5.5e-80 268.8 18.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KFL61219.1 - 6.7e-09 35.9 7.4 0.00048 20.4 0.3 3.5 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFL61219.1 - 9.9e-06 25.3 12.5 0.49 10.6 0.1 6.1 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFL61219.1 - 0.002 18.0 4.5 15 5.9 0.0 5.3 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFL61219.1 - 0.0024 18.0 12.3 0.97 9.8 0.1 5.4 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFL61219.1 - 0.012 16.2 12.6 3.5 8.5 0.1 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat NSF PF02071.20 KFL61219.1 - 0.052 14.3 20.4 0.12 13.2 0.4 6.3 6 0 0 6 6 5 0 Aromatic-di-Alanine (AdAR) repeat TPR_1 PF00515.28 KFL61219.1 - 0.062 13.1 14.8 2.3 8.2 1.0 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFL61219.1 - 0.12 13.1 15.9 5.1 7.8 3.8 4.5 1 1 3 4 4 4 0 Tetratricopeptide repeat CBP PF12192.8 KFL61219.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.2 2 1 0 2 2 2 0 Fungal calcium binding protein MIT PF04212.18 KFL61219.1 - 0.2 11.7 8.0 13 6.0 0.1 4.6 2 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain Glu-tRNAGln PF02686.15 KFL61220.1 - 8e-14 51.7 0.4 5.8e-13 48.9 0.4 2.1 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF2390 PF09523.10 KFL61220.1 - 0.047 14.0 1.0 1.1 9.6 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) DUF726 PF05277.12 KFL61221.1 - 5.5e-121 403.7 0.5 5.5e-121 403.7 0.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 KFL61221.1 - 0.085 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain RIBIOP_C PF04950.12 KFL61222.1 - 2.1e-109 365.5 0.0 6.5e-109 363.9 0.0 1.9 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFL61222.1 - 3.3e-22 78.4 0.0 7.6e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.19 KFL61223.1 - 1.8e-25 89.5 0.0 2.1e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KFL61223.1 - 0.0017 17.4 0.1 0.0021 17.1 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB COX6B PF02297.17 KFL61225.1 - 1.9e-19 69.7 7.1 2.2e-19 69.4 7.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb ketoacyl-synt PF00109.26 KFL61225.1 - 0.034 13.7 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain T2SSJ PF11612.8 KFL61225.1 - 0.041 14.1 0.5 0.77 10.0 0.5 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein J CHCH PF06747.13 KFL61225.1 - 0.042 14.0 1.2 0.11 12.7 1.3 1.7 1 1 0 1 1 1 0 CHCH domain CX9C PF16860.5 KFL61225.1 - 0.05 13.6 4.1 0.058 13.4 3.1 1.6 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 KFL61225.1 - 0.065 13.2 2.6 0.076 13.0 2.0 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain B12D PF06522.11 KFL61226.1 - 0.0048 16.7 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit SRA1 PF07304.11 KFL61227.1 - 6.3e-12 45.5 0.0 2.1e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 KFL61227.1 - 6.7e-08 32.5 0.2 2.2e-06 27.5 0.2 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 KFL61227.1 - 1.9e-07 31.7 3.3 0.19 12.7 0.0 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL61227.1 - 0.00018 21.8 0.1 0.037 14.3 0.1 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.15 KFL61227.1 - 0.0019 18.3 0.3 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 Prp18 domain RNA_pol_A_bac PF01000.26 KFL61228.1 - 2e-17 63.6 0.0 3e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFL61228.1 - 0.0014 18.0 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cytochrom_C PF00034.21 KFL61229.1 - 2.1e-11 44.8 0.0 4e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFL61229.1 - 9.2e-08 32.3 0.9 5.7e-07 29.8 0.9 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III BPS1 PF05633.11 KFL61229.1 - 0.011 14.8 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related CCP_MauG PF03150.14 KFL61229.1 - 0.014 16.0 0.0 0.024 15.3 0.0 1.5 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrom_C550 PF14495.6 KFL61229.1 - 0.025 14.3 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c-550 domain Subtilosin_A PF11420.8 KFL61229.1 - 7.4 6.6 6.5 0.67 10.0 0.3 2.4 3 0 0 3 3 3 0 Bacteriocin subtilosin A Cytochrom_C PF00034.21 KFL61230.1 - 3.3e-09 37.7 0.0 4.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFL61230.1 - 2.4e-05 24.6 0.7 0.00012 22.3 0.7 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III CCP_MauG PF03150.14 KFL61230.1 - 0.014 16.0 0.0 0.018 15.7 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrom_C PF00034.21 KFL61231.1 - 1.1e-11 45.6 0.0 1.6e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFL61231.1 - 5.6e-08 33.0 1.1 2.8e-07 30.8 1.1 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KFL61231.1 - 0.0016 18.1 0.2 0.0094 15.7 0.2 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.14 KFL61231.1 - 0.01 16.5 0.0 0.012 16.3 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrom_C PF00034.21 KFL61232.1 - 1e-09 39.4 0.0 1.2e-09 39.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFL61232.1 - 2.3e-05 24.6 0.9 2.8e-05 24.3 0.9 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KFL61232.1 - 0.0057 16.4 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.14 KFL61232.1 - 0.0061 17.2 0.0 0.0072 17.0 0.0 1.1 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase Cytochrom_C PF00034.21 KFL61233.1 - 1e-09 39.4 0.0 1.2e-09 39.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFL61233.1 - 2.3e-05 24.6 0.9 2.8e-05 24.3 0.9 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KFL61233.1 - 0.0057 16.4 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.14 KFL61233.1 - 0.0061 17.2 0.0 0.0072 17.0 0.0 1.1 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase F-box PF00646.33 KFL61239.1 - 0.004 17.0 0.1 0.0094 15.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain ATP-synt_ab PF00006.25 KFL61241.1 - 4.9e-68 229.0 0.0 6.3e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab PF00006.25 KFL61242.1 - 3.4e-68 229.5 0.0 4.4e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain HNH_2 PF13391.6 KFL61245.1 - 7.3e-15 54.9 0.2 5.5e-14 52.1 0.0 2.5 1 1 1 2 2 2 1 HNH endonuclease Nodulin-like PF06813.13 KFL61246.1 - 4.5e-22 78.8 4.9 6.5e-22 78.2 4.9 1.2 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 KFL61246.1 - 1.8e-12 46.9 21.0 7.9e-12 44.8 20.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL61246.1 - 0.33 9.8 13.6 0.72 8.6 12.4 2.1 2 1 1 3 3 3 0 Sugar (and other) transporter Nodulin-like PF06813.13 KFL61247.1 - 4.5e-22 78.8 4.9 6.5e-22 78.2 4.9 1.2 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 KFL61247.1 - 1.8e-12 46.9 21.0 7.9e-12 44.8 20.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL61247.1 - 0.33 9.8 13.6 0.72 8.6 12.4 2.1 2 1 1 3 3 3 0 Sugar (and other) transporter Nodulin-like PF06813.13 KFL61248.1 - 1.1e-06 28.4 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 KFL61248.1 - 0.038 12.9 2.5 0.23 10.4 2.0 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily VKOR PF07884.14 KFL61248.1 - 0.057 13.6 0.7 0.11 12.7 0.7 1.5 1 0 0 1 1 1 0 Vitamin K epoxide reductase family Nodulin-like PF06813.13 KFL61249.1 - 1.1e-06 28.4 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 KFL61249.1 - 0.038 12.9 2.5 0.23 10.4 2.0 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily VKOR PF07884.14 KFL61249.1 - 0.057 13.6 0.7 0.11 12.7 0.7 1.5 1 0 0 1 1 1 0 Vitamin K epoxide reductase family Serinc PF03348.15 KFL61250.1 - 5e-153 510.1 9.4 5.6e-153 509.9 9.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) YqhR PF11085.8 KFL61250.1 - 0.34 10.8 13.8 0.043 13.7 6.7 2.7 2 0 0 2 2 2 0 Conserved membrane protein YqhR DUF4148 PF13663.6 KFL61250.1 - 1.3 9.2 5.9 0.24 11.6 0.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Sugar_tr PF00083.24 KFL61251.1 - 0.0018 17.2 1.7 0.34 9.7 0.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Sugar_tr PF00083.24 KFL61252.1 - 9.2e-47 159.9 8.3 1e-46 159.8 8.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFL61252.1 - 4.1e-15 55.6 10.0 4.7e-15 55.4 10.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Med3 PF11593.8 KFL61255.1 - 1.7 7.7 12.4 2 7.5 12.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Semialdhyde_dhC PF02774.18 KFL61259.1 - 2.7e-37 128.6 0.0 4.1e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KFL61259.1 - 3.2e-29 101.8 0.0 1.6e-28 99.5 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KFL61259.1 - 0.0044 17.8 0.0 0.0091 16.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 KFL61259.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dhC PF02774.18 KFL61260.1 - 2.7e-37 128.6 0.0 4.1e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KFL61260.1 - 3.1e-29 101.9 0.0 1.6e-28 99.5 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KFL61260.1 - 0.0044 17.8 0.0 0.009 16.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 KFL61260.1 - 0.095 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Peptidase_M35 PF02102.15 KFL61261.1 - 3.4e-106 355.2 5.8 3.8e-106 355.0 5.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KFL61261.1 - 1.1e-42 146.0 0.6 2e-42 145.2 0.6 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KFL61261.1 - 0.00052 19.6 0.3 0.003 17.2 0.3 1.9 1 1 0 1 1 1 1 Putative peptidase family Peptidase_M35 PF02102.15 KFL61262.1 - 4.3e-86 289.0 5.6 5.2e-86 288.7 5.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KFL61262.1 - 6e-43 146.9 0.6 1.1e-42 146.0 0.6 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KFL61262.1 - 3.7e-05 23.4 0.5 0.00027 20.6 0.5 1.9 1 1 0 1 1 1 1 Putative peptidase family Polysacc_deac_1 PF01522.21 KFL61263.1 - 1e-27 96.5 0.0 2e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KFL61263.1 - 0.017 14.4 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Ribosomal_L16 PF00252.18 KFL61264.1 - 1.1e-29 103.1 0.2 1.3e-29 102.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CHCH PF06747.13 KFL61265.1 - 6e-07 29.4 5.3 1e-06 28.7 5.3 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KFL61265.1 - 0.0017 18.8 1.6 0.0033 17.8 1.6 1.6 1 0 0 1 1 1 1 GCK domain CHCH PF06747.13 KFL61266.1 - 0.00051 20.1 0.8 0.00085 19.4 0.8 1.3 1 0 0 1 1 1 1 CHCH domain DUF2981 PF11200.8 KFL61266.1 - 0.12 12.1 0.6 0.14 11.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Upf2 PF04050.14 KFL61267.1 - 1.7e-41 142.1 12.8 1.7e-41 142.1 12.8 2.3 2 1 1 3 3 3 1 Up-frameshift suppressor 2 MIF4G PF02854.19 KFL61268.1 - 2.8e-43 148.0 0.0 2.7e-22 79.5 0.0 3.6 4 0 0 4 4 4 3 MIF4G domain FliD_C PF07195.12 KFL61268.1 - 0.0053 16.2 3.4 0.011 15.2 3.4 1.5 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.10 KFL61271.1 - 0.4 10.9 8.1 1.2 9.3 1.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Glyco_transf_90 PF05686.12 KFL61272.1 - 5.3e-26 91.4 1.2 8e-26 90.9 1.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Ank_2 PF12796.7 KFL61272.1 - 1.5e-24 86.4 0.0 3.1e-11 43.7 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFL61272.1 - 4.2e-11 43.2 0.2 7.1e-05 23.3 0.0 4.1 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFL61272.1 - 1e-09 37.8 0.1 1.1 10.0 0.0 5.5 5 1 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KFL61272.1 - 4.8e-06 26.8 0.2 0.46 11.0 0.0 4.7 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFL61272.1 - 2e-05 24.8 0.2 0.12 12.8 0.1 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Glyco_trans_1_2 PF13524.6 KFL61272.1 - 0.052 14.0 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF2700 PF10912.8 KFL61282.1 - 0.11 12.5 2.0 0.2 11.7 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) DUF2700 PF10912.8 KFL61283.1 - 0.11 12.5 2.0 0.2 11.7 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) DUF2700 PF10912.8 KFL61284.1 - 0.11 12.5 2.0 0.2 11.7 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) WD40 PF00400.32 KFL61290.1 - 4.7e-49 163.3 20.1 4.1e-09 36.9 0.6 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KFL61290.1 - 2.5e-14 52.9 0.3 4.8e-14 52.0 0.3 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 KFL61290.1 - 3.4e-12 45.8 7.1 0.0034 16.1 0.1 5.8 5 1 1 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KFL61290.1 - 8e-11 42.1 0.4 0.00093 19.5 0.0 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KFL61290.1 - 9.2e-11 41.3 0.3 2.7e-10 39.8 0.1 1.9 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KFL61290.1 - 0.0006 19.7 0.1 0.0025 17.7 0.0 2.1 2 0 0 2 2 2 1 F-box WD40_like PF17005.5 KFL61290.1 - 0.0012 18.3 0.1 0.002 17.5 0.1 1.3 1 0 0 1 1 1 1 WD40-like domain PQQ PF01011.21 KFL61290.1 - 0.09 12.7 0.1 24 5.1 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat PRANC PF09372.10 KFL61290.1 - 0.19 12.1 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 PRANC domain Asp_decarbox PF02261.16 KFL61290.1 - 0.22 11.5 0.0 24 4.9 0.0 2.7 2 1 1 3 3 3 0 Aspartate decarboxylase SMC_hinge PF06470.13 KFL61292.1 - 2.1e-32 111.8 0.1 3.2e-31 108.1 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain APG6_N PF17675.1 KFL61292.1 - 0.00066 20.2 65.7 0.034 14.7 6.6 4.5 3 1 1 4 4 4 2 Apg6 coiled-coil region ATG16 PF08614.11 KFL61292.1 - 0.0072 16.6 61.3 0.71 10.1 11.0 5.3 3 2 2 5 5 5 4 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 KFL61292.1 - 2.2 8.6 37.5 0.6 10.4 2.4 5.5 3 2 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 KFL61292.1 - 3.4 7.0 58.4 1.5 8.1 16.4 4.4 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding EspB_PE PF18625.1 KFL61292.1 - 3.9 8.0 8.7 0.54 10.7 0.3 3.3 2 2 0 3 3 3 0 ESX-1 secreted protein B PE domain DUF16 PF01519.16 KFL61292.1 - 7 7.2 38.9 2.2 8.8 13.3 4.7 2 2 2 4 4 4 0 Protein of unknown function DUF16 DUF948 PF06103.11 KFL61292.1 - 9.6 6.5 17.3 1.5 9.1 3.9 4.4 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Sec34 PF04136.15 KFL61292.1 - 9.9 6.0 31.2 0.57 10.1 2.4 4.1 3 1 1 4 4 4 0 Sec34-like family NB-ARC PF00931.22 KFL61293.1 - 5.9e-17 61.7 0.0 8.6e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KFL61293.1 - 5.1e-05 23.7 0.3 0.0041 17.5 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 KFL61293.1 - 0.021 14.2 0.2 0.087 12.2 0.1 1.8 1 1 1 2 2 2 0 KaiC ATPase_2 PF01637.18 KFL61293.1 - 0.027 14.4 0.0 0.092 12.6 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KFL61293.1 - 0.029 14.6 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFL61293.1 - 0.06 13.3 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KFL61293.1 - 0.094 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.6 KFL61294.1 - 1.6e-13 50.7 2.5 7.7e-07 29.3 0.1 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFL61294.1 - 3.6e-06 26.7 1.2 0.019 15.0 0.1 4.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFL61294.1 - 1.8e-05 24.4 2.1 0.0015 18.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFL61294.1 - 5.3e-05 23.8 1.9 9 7.0 0.0 5.1 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFL61294.1 - 0.00071 20.0 2.1 19 5.8 0.1 4.0 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFL61294.1 - 0.0036 17.8 3.7 2.7 8.8 0.1 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFL61294.1 - 0.0077 16.0 0.2 0.041 13.7 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFL61294.1 - 0.013 15.6 1.0 1.7 9.1 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1961 PF09224.11 KFL61294.1 - 0.044 13.2 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) TPR_14 PF13428.6 KFL61294.1 - 0.21 12.5 4.5 42 5.3 0.0 4.3 4 2 1 5 5 5 0 Tetratricopeptide repeat CBM_21 PF03370.13 KFL61297.1 - 4e-30 104.3 0.0 7.8e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFL61297.1 - 5.7e-09 36.5 0.7 1.6e-08 35.0 0.3 2.0 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) P5CR_dimer PF14748.6 KFL61298.1 - 1.6e-31 108.6 3.3 2.3e-31 108.1 3.3 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFL61298.1 - 1.4e-08 35.2 0.0 5.7e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PIG-P PF08510.12 KFL61299.1 - 0.15 11.9 0.3 0.2 11.6 0.3 1.2 1 0 0 1 1 1 0 PIG-P DUF917 PF06032.12 KFL61300.1 - 1.3e-123 412.3 0.2 6.5e-122 406.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KFL61300.1 - 1.2e-25 90.4 6.9 2e-23 83.1 3.8 2.4 1 1 1 2 2 2 2 Hydantoinase/oxoprolinase StbA PF06406.11 KFL61300.1 - 0.077 12.2 1.7 2.1 7.5 0.1 2.3 1 1 0 2 2 2 0 StbA protein Fungal_trans PF04082.18 KFL61301.1 - 5.7e-06 25.6 1.1 1.3e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF5327 PF17261.2 KFL61301.1 - 0.3 11.9 6.6 0.66 10.7 6.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Suf PF05843.14 KFL61301.1 - 4.4 7.2 9.2 6.9 6.6 9.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 KFL61301.1 - 8.9 4.4 14.5 12 4.0 14.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zn_clus PF00172.18 KFL61302.1 - 0.00028 20.9 12.7 0.00044 20.3 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANAPC1 PF12859.7 KFL61302.1 - 0.082 13.5 1.9 0.11 13.0 1.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Dickkopf_N PF04706.12 KFL61302.1 - 2.8 8.5 11.3 5.4 7.6 9.9 1.9 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Proteasome PF00227.26 KFL61303.1 - 9.3e-53 178.5 0.0 8.2e-28 97.2 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit Proteasome PF00227.26 KFL61304.1 - 9.3e-53 178.5 0.0 8.2e-28 97.2 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit Proteasome PF00227.26 KFL61305.1 - 2.8e-57 193.3 0.0 4e-33 114.5 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KFL61305.1 - 7e-11 41.6 0.1 2.6e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Proteasome PF00227.26 KFL61306.1 - 3.1e-52 176.8 0.0 5.4e-28 97.8 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit Proteasome PF00227.26 KFL61307.1 - 8e-42 142.9 0.0 1.2e-22 80.3 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit Proteasome PF00227.26 KFL61308.1 - 8e-42 142.9 0.0 1.2e-22 80.3 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit LSM PF01423.22 KFL61310.1 - 4.8e-09 35.8 2.1 0.00079 19.1 0.1 2.4 3 0 0 3 3 3 2 LSM domain LSM PF01423.22 KFL61311.1 - 1.8e-14 53.2 0.1 1.8e-14 53.2 0.1 1.4 2 0 0 2 2 2 1 LSM domain DUF334 PF03904.13 KFL61311.1 - 0.12 11.9 0.1 0.32 10.5 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF334) LSM PF01423.22 KFL61312.1 - 1.5e-14 53.4 0.1 1.5e-14 53.4 0.1 1.4 2 0 0 2 2 2 1 LSM domain BCDHK_Adom3 PF10436.9 KFL61314.1 - 1.2e-72 243.0 0.0 1.8e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFL61314.1 - 1.1e-09 38.7 0.0 5.2e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFL61314.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.9 KFL61315.1 - 3.1e-46 157.2 0.0 4.5e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFL61315.1 - 4.2e-13 49.8 0.0 2.2e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFL61315.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.9 KFL61316.1 - 2.7e-46 157.4 0.0 3.9e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFL61316.1 - 7.3e-10 39.3 0.0 3.7e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFL61316.1 - 0.015 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.9 KFL61317.1 - 1.2e-35 122.8 0.0 1.7e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFL61317.1 - 3.1e-13 50.2 0.0 1.8e-12 47.8 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFL61317.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.9 KFL61318.1 - 1.1e-35 122.9 0.0 1.5e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFL61318.1 - 5.3e-10 39.8 0.0 2.9e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFL61318.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LSM PF01423.22 KFL61319.1 - 5.6e-18 64.4 0.0 7.1e-18 64.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFL61319.1 - 0.0049 17.0 0.0 0.0077 16.4 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain HNH_2 PF13391.6 KFL61321.1 - 9.4e-13 48.1 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.6 KFL61322.1 - 5.9e-09 35.9 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.6 KFL61323.1 - 5.9e-09 35.9 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease AAA PF00004.29 KFL61324.1 - 1.5e-16 61.0 0.7 5.3e-16 59.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFL61324.1 - 0.00026 21.0 0.0 0.00079 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFL61324.1 - 0.0018 18.7 0.8 0.0077 16.6 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFL61324.1 - 0.0067 16.7 3.6 0.014 15.7 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.6 KFL61324.1 - 0.011 15.5 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFL61324.1 - 0.043 13.6 0.0 0.043 13.6 0.0 4.5 2 1 0 3 3 3 0 AAA domain AAA_33 PF13671.6 KFL61324.1 - 0.15 12.2 0.0 0.15 12.2 0.0 3.3 3 1 0 3 3 3 0 AAA domain Peptidase_S64 PF08192.11 KFL61324.1 - 7 5.0 30.6 12 4.2 30.6 1.5 1 0 0 1 1 1 0 Peptidase family S64 Sec7_N PF12783.7 KFL61327.1 - 1.7e-22 80.0 7.3 2.1e-22 79.7 4.2 2.2 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KFL61327.1 - 3e-18 66.1 0.2 7.1e-18 64.9 0.2 1.6 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF3533 PF12051.8 KFL61327.1 - 0.064 12.2 0.1 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Methyltransf_10 PF05971.12 KFL61329.1 - 3.3e-14 52.9 0.1 3.9e-14 52.7 0.1 1.0 1 0 0 1 1 1 1 RNA methyltransferase Cation_ATPase PF13246.6 KFL61330.1 - 0.045 13.8 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 Cation transport ATPase (P-type) HEAT PF02985.22 KFL61332.1 - 0.074 13.3 0.1 2.2 8.8 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat DUF1852 PF08908.11 KFL61333.1 - 0.035 13.1 0.0 0.061 12.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1852) Nup188 PF10487.9 KFL61333.1 - 0.14 10.0 0.0 0.16 9.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 Tim17 PF02466.19 KFL61335.1 - 6.5e-28 97.3 3.8 8.5e-28 97.0 3.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ILVD_EDD PF00920.21 KFL61336.1 - 1.2e-209 697.3 0.2 1.3e-209 697.1 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 KFL61336.1 - 0.086 13.0 0.0 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain ILVD_EDD PF00920.21 KFL61337.1 - 1e-161 539.1 0.0 1.4e-161 538.7 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 KFL61337.1 - 0.064 13.5 0.1 0.35 11.1 0.0 2.2 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain Lipase_3 PF01764.25 KFL61338.1 - 2.3e-19 69.7 0.0 4.8e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) CBFD_NFYB_HMF PF00808.23 KFL61340.1 - 3e-05 24.2 0.1 4.8e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Dapper PF15268.6 KFL61340.1 - 0.15 10.9 20.8 0.18 10.6 20.8 1.0 1 0 0 1 1 1 0 Dapper eIF-3_zeta PF05091.12 KFL61340.1 - 0.4 9.6 11.5 0.5 9.3 11.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.6 KFL61340.1 - 5.8 6.2 7.8 8.9 5.6 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YL1 PF05764.13 KFL61340.1 - 9.1 6.3 16.3 13 5.8 16.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein WD40_4 PF16300.5 KFL61342.1 - 4.5e-20 71.3 0.2 9.2e-20 70.3 0.2 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFL61342.1 - 3.7e-17 62.4 4.4 0.00038 21.2 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1899 PF08953.11 KFL61342.1 - 1.1e-10 41.2 0.0 2.9e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 KFL61342.1 - 3.3e-07 30.5 0.0 0.0019 18.5 0.1 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFL61342.1 - 0.017 13.8 0.2 0.04 12.6 0.2 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 eIF2A PF08662.11 KFL61342.1 - 0.021 14.7 0.0 1.1 9.2 0.0 2.5 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Sugar_tr PF00083.24 KFL61344.1 - 2.2e-41 142.2 3.7 2.5e-41 142.0 3.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter SYS1 PF09801.9 KFL61344.1 - 0.023 14.9 0.4 0.039 14.1 0.4 1.4 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network Nramp PF01566.18 KFL61345.1 - 4.2e-39 134.5 11.4 4.2e-39 134.5 11.4 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Nramp PF01566.18 KFL61346.1 - 9.3e-37 126.8 5.6 9.3e-37 126.8 5.6 2.5 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein CAML PF14963.6 KFL61346.1 - 0.47 10.5 1.7 1.3 9.1 0.3 2.0 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand DUF1129 PF06570.11 KFL61346.1 - 4 6.9 8.7 0.24 10.9 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2628 PF10947.8 KFL61346.1 - 7.7 6.9 8.6 4.1 7.8 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2628) Sec1 PF00995.23 KFL61348.1 - 1.3e-107 361.4 0.0 1.6e-107 361.1 0.0 1.1 1 0 0 1 1 1 1 Sec1 family DUF1043 PF06295.12 KFL61348.1 - 0.23 11.5 0.8 0.52 10.3 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Sec1 PF00995.23 KFL61349.1 - 1.3e-107 361.4 0.0 1.6e-107 361.1 0.0 1.1 1 0 0 1 1 1 1 Sec1 family DUF1043 PF06295.12 KFL61349.1 - 0.23 11.5 0.8 0.52 10.3 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Sec1 PF00995.23 KFL61350.1 - 1.3e-107 361.4 0.0 1.6e-107 361.1 0.0 1.1 1 0 0 1 1 1 1 Sec1 family DUF1043 PF06295.12 KFL61350.1 - 0.23 11.5 0.8 0.52 10.3 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Sec1 PF00995.23 KFL61351.1 - 7.6e-89 299.5 0.0 9.5e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family DUF1043 PF06295.12 KFL61351.1 - 0.16 12.0 0.7 0.42 10.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Sec1 PF00995.23 KFL61352.1 - 7.6e-89 299.5 0.0 9.5e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family DUF1043 PF06295.12 KFL61352.1 - 0.16 12.0 0.7 0.42 10.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Sec1 PF00995.23 KFL61353.1 - 7.6e-89 299.5 0.0 9.5e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family DUF1043 PF06295.12 KFL61353.1 - 0.16 12.0 0.7 0.42 10.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) p450 PF00067.22 KFL61355.1 - 4.4e-28 98.2 0.0 5.2e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IlvN PF07991.12 KFL61360.1 - 2.4e-45 154.1 0.0 3.8e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KFL61360.1 - 3.1e-39 134.6 0.1 6.1e-39 133.6 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KFL61360.1 - 0.076 13.6 0.2 0.41 11.2 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KFL61360.1 - 0.089 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase COX6C PF02937.15 KFL61361.1 - 0.08 13.1 0.0 0.086 13.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc UQ_con PF00179.26 KFL61362.1 - 2.2e-26 92.2 0.0 2.8e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFL61362.1 - 0.17 11.6 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UQ_con PF00179.26 KFL61363.1 - 1.4e-35 121.9 0.0 1.7e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFL61363.1 - 0.055 13.2 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B Chitin_synth_1 PF01644.17 KFL61364.1 - 4.4e-69 231.6 0.0 6.4e-69 231.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KFL61364.1 - 2.6e-28 97.8 0.0 4.8e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFL61364.1 - 9.5e-23 80.6 0.1 3.8e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFL61364.1 - 8.1e-09 35.7 0.1 8.1e-09 35.7 0.1 2.4 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Psu PF07455.11 KFL61364.1 - 0.04 13.5 0.0 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) Chitin_synth_1 PF01644.17 KFL61365.1 - 3.1e-69 232.1 0.0 4.5e-69 231.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KFL61365.1 - 4.9e-23 81.5 0.1 2.6e-18 66.0 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFL61365.1 - 5.4e-09 36.2 0.1 5.4e-09 36.2 0.1 2.5 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Psu PF07455.11 KFL61365.1 - 0.0018 17.9 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 2 Phage polarity suppression protein (Psu) Chitin_synth_1 PF01644.17 KFL61366.1 - 2.9e-69 232.2 0.0 4.1e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KFL61366.1 - 4.2e-23 81.8 0.1 2.3e-18 66.1 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFL61366.1 - 4.9e-09 36.4 0.1 4.9e-09 36.4 0.1 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Psu PF07455.11 KFL61366.1 - 0.023 14.3 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) Chitin_synth_1 PF01644.17 KFL61367.1 - 2.7e-69 232.3 0.0 3.8e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KFL61367.1 - 1.7e-28 98.4 0.0 3.2e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFL61367.1 - 1.5e-18 66.7 0.0 2.1e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KFL61367.1 - 1.8e-09 37.8 0.2 4.5e-09 36.5 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_1 PF01644.17 KFL61368.1 - 2.7e-69 232.3 0.0 3.8e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KFL61368.1 - 1.7e-28 98.4 0.0 3.2e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFL61368.1 - 1.5e-18 66.7 0.0 2.1e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KFL61368.1 - 1.8e-09 37.8 0.2 4.5e-09 36.5 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 AMP-binding PF00501.28 KFL61369.1 - 2e-36 125.5 0.0 2.4e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF4453 PF14627.6 KFL61371.1 - 0.059 13.5 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) WW PF00397.26 KFL61372.1 - 1.7e-06 28.0 0.4 3.9e-06 26.8 0.4 1.7 1 0 0 1 1 1 1 WW domain zf-C2H2 PF00096.26 KFL61380.1 - 1.8e-07 31.2 4.4 0.00065 20.0 1.3 2.7 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KFL61380.1 - 4.5e-05 23.7 0.1 7.1e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Aberrant zinc-finger Spc29 PF17082.5 KFL61380.1 - 0.0002 21.3 0.2 0.00035 20.5 0.2 1.4 1 0 0 1 1 1 1 Spindle Pole Component 29 APC_N_CC PF16689.5 KFL61380.1 - 0.0051 16.9 0.3 0.011 15.8 0.1 1.6 2 0 0 2 2 2 1 Coiled-coil N-terminus of APC, dimerisation domain ATG16 PF08614.11 KFL61380.1 - 0.017 15.4 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-C2H2_4 PF13894.6 KFL61380.1 - 0.017 15.9 1.1 4.6 8.3 0.2 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger FAM76 PF16046.5 KFL61380.1 - 0.043 13.2 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 FAM76 protein Cep57_MT_bd PF06657.13 KFL61380.1 - 0.045 14.2 2.4 4.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Geminin PF07412.12 KFL61380.1 - 0.1 12.4 0.6 0.18 11.5 0.4 1.5 1 1 0 1 1 1 0 Geminin Kinesin_assoc PF16183.5 KFL61380.1 - 0.12 12.5 0.1 3 8.0 0.1 2.2 2 0 0 2 2 2 0 Kinesin-associated MPS2 PF17060.5 KFL61380.1 - 0.17 11.2 0.5 0.23 10.7 0.5 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Lebercilin PF15619.6 KFL61380.1 - 0.19 11.4 4.9 0.29 10.8 1.0 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease zf-H2C2_2 PF13465.6 KFL61380.1 - 2.6 8.6 13.7 12 6.5 2.9 3.6 3 1 0 3 3 3 0 Zinc-finger double domain Alpha_GJ PF03229.13 KFL61381.1 - 0.22 12.1 3.1 0.25 11.9 3.1 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J Spt20 PF12090.8 KFL61381.1 - 3.4 7.2 18.1 4.2 6.9 18.1 1.1 1 0 0 1 1 1 0 Spt20 family Borrelia_P83 PF05262.11 KFL61381.1 - 4.2 5.7 16.7 4.2 5.7 16.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Selenoprotein_S PF06936.11 KFL61381.1 - 8.7 6.1 15.0 9.8 5.9 15.0 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) SNF2_N PF00176.23 KFL61382.1 - 1.3e-63 214.9 0.1 4.4e-63 213.1 0.1 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFL61382.1 - 1.1e-21 77.2 0.0 9e-21 74.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFL61382.1 - 3.7e-07 30.3 0.0 9.7e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFL61382.1 - 5e-06 25.9 0.0 0.0043 16.3 0.0 3.2 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KFL61382.1 - 0.00012 21.4 0.0 0.00028 20.2 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Cullin PF00888.22 KFL61383.1 - 1e-188 628.9 4.7 1.3e-188 628.6 4.7 1.0 1 0 0 1 1 1 1 Cullin family Cullin PF00888.22 KFL61384.1 - 3e-184 614.1 4.1 4e-184 613.7 4.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFL61384.1 - 5.8e-27 93.5 4.6 6.1e-27 93.5 2.3 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Pkinase PF00069.25 KFL61385.1 - 1.6e-57 194.9 0.0 2.3e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61385.1 - 6.1e-27 94.5 0.0 8.2e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFL61385.1 - 1.3e-05 24.4 0.1 1.8e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFL61385.1 - 0.00042 19.7 0.1 0.0013 18.1 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFL61385.1 - 0.00069 19.6 0.0 0.0021 18.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFL61385.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 KFL61385.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KFL61385.1 - 0.035 13.7 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KFL61385.1 - 0.23 10.2 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KFL61386.1 - 4.7e-50 170.4 0.0 6.6e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61386.1 - 8.3e-21 74.4 0.0 1.1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFL61386.1 - 6.8e-05 22.0 0.0 9.6e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFL61386.1 - 0.00057 19.9 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFL61386.1 - 0.0036 16.7 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFL61386.1 - 0.011 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KFL61386.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KFL61386.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KFL61386.1 - 0.2 10.4 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase G-alpha PF00503.20 KFL61387.1 - 3.1e-104 349.0 0.2 3.6e-104 348.7 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFL61387.1 - 2.4e-11 43.4 0.6 2.6e-10 40.0 0.3 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 KFL61388.1 - 1.7e-104 349.8 0.2 1.9e-104 349.6 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFL61388.1 - 4.9e-09 35.9 1.0 4.2e-08 32.9 0.5 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 KFL61389.1 - 6e-108 361.2 0.1 6.8e-108 361.0 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFL61389.1 - 2.1e-11 43.6 0.6 2.2e-10 40.2 0.3 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family Phosphorylase PF00343.20 KFL61390.1 - 7.4e-275 913.7 0.0 9.4e-275 913.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase ABC_membrane_2 PF06472.15 KFL61392.1 - 1.3e-63 214.9 0.0 1.8e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFL61392.1 - 8.9e-19 68.4 0.0 1.6e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFL61392.1 - 4.2e-05 23.5 0.0 0.00011 22.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFL61392.1 - 0.0027 18.3 0.1 0.0081 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFL61392.1 - 0.0053 16.5 0.0 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KFL61392.1 - 0.024 14.1 0.0 0.069 12.6 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 KFL61392.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 KFL61392.1 - 0.092 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KFL61392.1 - 0.12 12.8 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 KFL61392.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain LRR_6 PF13516.6 KFL61393.1 - 0.00038 20.3 2.0 2 8.7 0.0 5.4 6 0 0 6 6 6 1 Leucine Rich repeat DUF3135 PF11333.8 KFL61393.1 - 0.0031 17.7 1.2 0.15 12.3 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3135) LRR_6 PF13516.6 KFL61394.1 - 0.00034 20.4 2.0 1.9 8.7 0.0 5.5 6 0 0 6 6 6 3 Leucine Rich repeat DALR_2 PF09190.11 KFL61395.1 - 0.069 13.6 0.2 0.099 13.1 0.2 1.3 1 0 0 1 1 1 0 DALR domain Coatomer_E PF04733.14 KFL61397.1 - 4.9e-57 193.5 5.9 5.9e-57 193.3 5.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KFL61397.1 - 2.6e-09 37.4 17.6 0.00025 21.5 2.7 4.4 2 1 3 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFL61397.1 - 1.9e-08 34.4 4.3 0.0068 16.6 0.8 3.2 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KFL61397.1 - 1.2e-07 32.3 18.3 0.0011 19.5 2.3 4.3 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFL61397.1 - 1.4e-05 25.5 15.2 0.052 14.4 0.0 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFL61397.1 - 0.0002 21.6 13.0 0.041 14.2 1.3 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFL61397.1 - 0.00024 21.5 0.7 0.24 12.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFL61397.1 - 0.004 16.9 1.9 0.67 9.9 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Peptidase_S11 PF00768.20 KFL61397.1 - 0.0076 15.7 0.2 0.0091 15.5 0.2 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase TPR_2 PF07719.17 KFL61397.1 - 0.0085 16.1 13.6 0.09 12.9 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFL61397.1 - 0.038 13.2 8.2 0.032 13.4 1.4 2.7 1 1 1 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.12 KFL61397.1 - 0.048 13.7 0.7 0.1 12.7 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF627) TPR_9 PF13371.6 KFL61397.1 - 0.077 13.2 4.0 0.44 10.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 KFL61397.1 - 0.17 12.0 5.8 0.35 11.0 2.5 2.9 1 1 1 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_10 PF13374.6 KFL61397.1 - 0.21 11.5 6.7 27 4.8 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFL61397.1 - 1.1 10.1 19.6 2.2 9.2 0.1 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFL61397.1 - 4.8 7.6 10.9 4.9 7.6 1.9 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 KFL61398.1 - 2.4e-21 76.6 0.0 9.2e-21 74.7 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFL61398.1 - 3.7e-21 75.4 0.0 4.6e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KFL61398.1 - 0.064 12.7 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.28 KFL61398.1 - 0.11 11.4 0.2 7.9 5.2 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family DUF2974 PF11187.8 KFL61398.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PMI_typeI PF01238.21 KFL61399.1 - 1.1e-126 423.1 0.0 1.3e-126 422.8 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 KFL61399.1 - 0.081 12.8 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain Cas_TM1802 PF09484.10 KFL61399.1 - 0.1 11.3 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) Methyltransf_23 PF13489.6 KFL61400.1 - 8.1e-15 55.0 0.0 9.8e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFL61400.1 - 4.2e-13 49.8 0.0 3.6e-12 46.8 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFL61400.1 - 2e-12 47.6 0.0 4.8e-12 46.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFL61400.1 - 1e-11 44.9 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFL61400.1 - 1.3e-11 45.1 0.0 2.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFL61400.1 - 0.0047 16.3 0.0 0.028 13.8 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 KFL61400.1 - 0.0063 15.6 0.0 0.022 13.9 0.0 1.9 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_PK PF05891.12 KFL61400.1 - 0.013 15.0 0.0 0.11 12.0 0.0 2.0 1 1 1 2 2 2 0 AdoMet dependent proline di-methyltransferase Methyltransf_19 PF04672.12 KFL61400.1 - 0.017 14.6 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl methyltransferase Methyltransf_24 PF13578.6 KFL61400.1 - 0.056 14.5 0.0 0.15 13.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DUF1871 PF08958.10 KFL61400.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1871) Methyltransf_2 PF00891.18 KFL61400.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain EamA PF00892.20 KFL61401.1 - 1.1e-05 25.6 1.2 1.1e-05 25.6 1.2 2.9 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 KFL61401.1 - 0.0061 15.5 8.9 0.15 11.0 0.1 2.9 2 1 0 2 2 2 2 Ceramide synthase regulator Pyrid_oxidase_2 PF13883.6 KFL61402.1 - 6.1e-36 123.9 0.0 1.1e-35 123.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KFL61402.1 - 0.0074 16.5 0.0 0.019 15.2 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CYTH PF01928.21 KFL61402.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 CYTH domain Zip PF02535.22 KFL61406.1 - 5.5e-52 177.0 2.4 6.9e-52 176.7 2.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ni_hydr_CYTB PF01292.20 KFL61406.1 - 2.2 7.8 13.6 0.02 14.5 3.6 2.4 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 CPP1-like PF11833.8 KFL61406.1 - 3.8 7.1 6.0 6.4 6.4 0.2 3.2 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Zip PF02535.22 KFL61407.1 - 1.1e-34 120.2 0.2 1.4e-34 119.8 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter CPP1-like PF11833.8 KFL61407.1 - 2.8 7.5 6.0 5.1 6.7 0.2 3.0 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Ni_hydr_CYTB PF01292.20 KFL61407.1 - 4.2 6.9 14.2 0.014 15.0 3.6 2.1 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 Zip PF02535.22 KFL61408.1 - 2.1e-28 99.6 0.1 2.9e-28 99.1 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ni_hydr_CYTB PF01292.20 KFL61408.1 - 1.1 8.9 13.0 0.013 15.1 3.6 2.2 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 CPP1-like PF11833.8 KFL61408.1 - 3.2 7.4 5.9 6.7 6.3 0.1 3.0 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Zip PF02535.22 KFL61409.1 - 2.1e-28 99.6 0.1 2.9e-28 99.1 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ni_hydr_CYTB PF01292.20 KFL61409.1 - 1.1 8.9 13.0 0.013 15.1 3.6 2.2 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 CPP1-like PF11833.8 KFL61409.1 - 3.2 7.4 5.9 6.7 6.3 0.1 3.0 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Zip PF02535.22 KFL61410.1 - 2.4e-52 178.2 2.4 2.8e-52 178.0 2.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter ABC_membrane PF00664.23 KFL61414.1 - 2.9e-86 289.5 31.4 9e-46 156.7 12.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61414.1 - 3.9e-50 169.9 0.0 7.6e-29 101.0 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFL61414.1 - 4.5e-10 39.3 0.5 0.00032 20.2 0.0 4.0 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFL61414.1 - 3.8e-06 26.9 1.0 0.0018 18.2 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFL61414.1 - 4.3e-06 26.8 1.9 0.037 14.1 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KFL61414.1 - 0.00024 21.5 1.0 0.31 11.4 0.7 2.8 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KFL61414.1 - 0.0022 18.0 0.7 0.19 11.7 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KFL61414.1 - 0.0028 17.4 0.3 1.6 8.5 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFL61414.1 - 0.0046 17.5 0.3 0.33 11.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KFL61414.1 - 0.0092 15.7 0.1 3.9 7.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 KFL61414.1 - 0.013 15.7 3.4 17 5.6 0.0 4.2 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KFL61414.1 - 0.015 15.4 2.4 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KFL61414.1 - 0.021 15.2 0.0 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 KFL61414.1 - 0.023 15.0 2.7 3.7 7.8 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 KFL61414.1 - 0.034 14.0 0.8 0.65 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUP PF00674.18 KFL61414.1 - 0.055 13.6 0.7 0.36 11.0 0.7 2.5 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61414.1 - 0.066 13.1 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) IstB_IS21 PF01695.17 KFL61414.1 - 0.29 10.9 1.3 15 5.3 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein NACHT PF05729.12 KFL61414.1 - 0.31 10.9 5.4 6.5 6.6 0.1 3.2 3 0 0 3 3 3 0 NACHT domain ABC_membrane PF00664.23 KFL61415.1 - 2.7e-86 289.6 31.4 8.8e-46 156.8 12.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61415.1 - 9.1e-52 175.2 0.0 1.8e-30 106.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFL61415.1 - 5e-10 39.2 1.0 0.00021 20.8 0.1 4.0 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFL61415.1 - 3.6e-06 27.0 1.0 0.0018 18.2 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFL61415.1 - 4.1e-06 26.8 1.9 0.036 14.1 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KFL61415.1 - 2.7e-05 24.6 0.9 0.027 14.8 0.7 2.6 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KFL61415.1 - 0.0022 18.1 0.7 0.19 11.8 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KFL61415.1 - 0.0026 17.4 0.3 1.6 8.5 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFL61415.1 - 0.0043 17.6 0.3 0.32 11.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KFL61415.1 - 0.0059 16.4 0.4 3.8 7.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 KFL61415.1 - 0.012 15.8 3.4 17 5.7 0.0 4.2 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KFL61415.1 - 0.014 15.5 2.4 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KFL61415.1 - 0.02 15.3 0.0 1.7 9.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 KFL61415.1 - 0.031 14.1 0.7 0.64 9.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFL61415.1 - 0.033 14.4 3.3 3.7 7.8 0.1 3.2 2 1 0 2 2 2 0 AAA domain DUP PF00674.18 KFL61415.1 - 0.055 13.6 0.7 0.36 11.0 0.7 2.5 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61415.1 - 0.066 13.1 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) IstB_IS21 PF01695.17 KFL61415.1 - 0.27 11.0 1.3 15 5.3 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein NACHT PF05729.12 KFL61415.1 - 0.46 10.4 5.0 6.4 6.7 0.1 3.2 3 0 0 3 3 3 0 NACHT domain ABC_membrane PF00664.23 KFL61416.1 - 2.7e-86 289.6 31.4 8.7e-46 156.8 12.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61416.1 - 2.1e-48 164.3 0.0 4.5e-27 95.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 KFL61416.1 - 3.6e-06 27.0 1.0 0.0018 18.2 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFL61416.1 - 4.3e-06 26.8 1.9 0.036 14.1 0.1 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase SMC_N PF02463.19 KFL61416.1 - 0.00021 20.8 0.0 9 5.7 0.0 3.9 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFL61416.1 - 0.0023 18.3 0.2 3.7 7.9 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KFL61416.1 - 0.0023 18.0 0.7 0.19 11.8 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KFL61416.1 - 0.0027 17.4 0.3 1.6 8.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFL61416.1 - 0.0043 17.6 0.3 0.32 11.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 KFL61416.1 - 0.012 15.8 3.4 17 5.7 0.0 4.2 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KFL61416.1 - 0.016 15.3 2.4 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KFL61416.1 - 0.02 15.3 0.0 1.7 9.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 KFL61416.1 - 0.031 14.1 0.5 0.64 9.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KFL61416.1 - 0.033 13.9 0.1 3.8 7.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KFL61416.1 - 0.036 14.3 1.1 3.6 7.8 0.1 3.0 3 0 0 3 3 3 0 AAA domain DUP PF00674.18 KFL61416.1 - 0.054 13.6 0.7 0.36 11.0 0.7 2.5 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61416.1 - 0.068 13.0 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) ABC_membrane PF00664.23 KFL61417.1 - 2.5e-86 289.7 31.4 8.5e-46 156.8 12.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61417.1 - 6.4e-50 169.2 0.0 1.3e-28 100.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 KFL61417.1 - 3.4e-06 27.1 1.0 0.0017 18.3 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFL61417.1 - 4.2e-06 26.8 1.9 0.035 14.2 0.1 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase SMC_N PF02463.19 KFL61417.1 - 0.00022 20.7 0.1 8.8 5.7 0.0 3.9 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFL61417.1 - 0.0019 18.6 0.2 2.6 8.4 0.2 2.7 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KFL61417.1 - 0.0022 18.0 0.7 0.19 11.8 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KFL61417.1 - 0.0026 17.5 0.3 1.6 8.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFL61417.1 - 0.0041 17.6 0.3 0.32 11.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 KFL61417.1 - 0.012 15.9 3.4 17 5.7 0.0 4.2 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KFL61417.1 - 0.015 15.4 2.4 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KFL61417.1 - 0.019 15.4 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 KFL61417.1 - 0.037 13.8 1.0 0.62 9.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFL61417.1 - 0.039 14.2 1.8 3.6 7.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KFL61417.1 - 0.039 13.7 0.1 3.7 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUP PF00674.18 KFL61417.1 - 0.051 13.7 0.7 0.35 11.0 0.7 2.5 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61417.1 - 0.064 13.1 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) ABC_membrane PF00664.23 KFL61418.1 - 2.4e-86 289.8 31.4 8.3e-46 156.8 12.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61418.1 - 1.5e-51 174.5 0.0 3.2e-30 105.4 0.1 2.6 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 KFL61418.1 - 3.3e-06 27.1 1.0 0.0017 18.3 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFL61418.1 - 4.1e-06 26.9 1.9 0.035 14.2 0.1 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase SMC_N PF02463.19 KFL61418.1 - 0.00021 20.8 0.3 8.6 5.7 0.0 3.9 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFL61418.1 - 0.00031 21.2 0.2 0.38 11.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KFL61418.1 - 0.0022 18.1 0.7 0.18 11.8 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KFL61418.1 - 0.0024 17.5 0.3 1.6 8.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFL61418.1 - 0.0039 17.7 0.3 0.31 11.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 KFL61418.1 - 0.011 16.0 3.4 16 5.7 0.0 4.2 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KFL61418.1 - 0.014 15.5 2.4 1.6 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KFL61418.1 - 0.018 15.4 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 KFL61418.1 - 0.027 14.2 0.1 3.6 7.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KFL61418.1 - 0.03 14.2 0.7 0.61 9.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFL61418.1 - 0.051 13.9 2.1 3.5 7.9 0.1 3.0 2 1 0 2 2 2 0 AAA domain DUP PF00674.18 KFL61418.1 - 0.051 13.7 0.7 0.34 11.1 0.7 2.5 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61418.1 - 0.064 13.1 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) ABC_membrane PF00664.23 KFL61419.1 - 1.8e-86 290.2 31.4 7.1e-46 157.1 12.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61419.1 - 4.2e-28 98.6 0.1 2.9e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KFL61419.1 - 3.2e-06 27.2 1.6 0.031 14.3 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFL61419.1 - 4.9e-06 26.6 0.6 0.0015 18.5 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KFL61419.1 - 0.0012 18.3 0.2 7.7 5.9 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 KFL61419.1 - 0.0018 18.4 0.7 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KFL61419.1 - 0.002 17.8 0.3 1.4 8.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFL61419.1 - 0.003 18.1 0.4 0.28 11.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFL61419.1 - 0.0093 16.4 0.1 5.6 7.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KFL61419.1 - 0.013 15.6 2.4 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KFL61419.1 - 0.019 15.4 0.0 1.5 9.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KFL61419.1 - 0.02 15.1 4.0 15 5.9 0.0 4.3 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUP PF00674.18 KFL61419.1 - 0.04 14.0 0.7 0.31 11.2 0.7 2.6 1 0 0 1 1 1 0 DUP family AAA_22 PF13401.6 KFL61419.1 - 0.051 13.9 0.9 3.2 8.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF720 PF05302.11 KFL61419.1 - 0.056 13.3 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) AAA_21 PF13304.6 KFL61419.1 - 0.059 13.2 0.5 0.55 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KFL61419.1 - 0.1 12.3 0.1 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 KFL61420.1 - 1.8e-86 290.2 31.4 7.1e-46 157.1 12.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61420.1 - 4.2e-28 98.6 0.1 2.9e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KFL61420.1 - 3.2e-06 27.2 1.6 0.031 14.3 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFL61420.1 - 4.9e-06 26.6 0.6 0.0015 18.5 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KFL61420.1 - 0.0012 18.3 0.2 7.7 5.9 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 KFL61420.1 - 0.0018 18.4 0.7 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KFL61420.1 - 0.002 17.8 0.3 1.4 8.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFL61420.1 - 0.003 18.1 0.4 0.28 11.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFL61420.1 - 0.0093 16.4 0.1 5.6 7.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KFL61420.1 - 0.013 15.6 2.4 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KFL61420.1 - 0.019 15.4 0.0 1.5 9.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KFL61420.1 - 0.02 15.1 4.0 15 5.9 0.0 4.3 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUP PF00674.18 KFL61420.1 - 0.04 14.0 0.7 0.31 11.2 0.7 2.6 1 0 0 1 1 1 0 DUP family AAA_22 PF13401.6 KFL61420.1 - 0.051 13.9 0.9 3.2 8.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF720 PF05302.11 KFL61420.1 - 0.056 13.3 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) AAA_21 PF13304.6 KFL61420.1 - 0.059 13.2 0.5 0.55 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KFL61420.1 - 0.1 12.3 0.1 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 KFL61421.1 - 1.8e-86 290.2 31.4 7.1e-46 157.1 12.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61421.1 - 4.2e-28 98.6 0.1 2.9e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KFL61421.1 - 3.2e-06 27.2 1.6 0.031 14.3 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFL61421.1 - 4.9e-06 26.6 0.6 0.0015 18.5 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KFL61421.1 - 0.0012 18.3 0.2 7.7 5.9 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 KFL61421.1 - 0.0018 18.4 0.7 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KFL61421.1 - 0.002 17.8 0.3 1.4 8.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFL61421.1 - 0.003 18.1 0.4 0.28 11.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFL61421.1 - 0.0093 16.4 0.1 5.6 7.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KFL61421.1 - 0.013 15.6 2.4 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KFL61421.1 - 0.019 15.4 0.0 1.5 9.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KFL61421.1 - 0.02 15.1 4.0 15 5.9 0.0 4.3 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUP PF00674.18 KFL61421.1 - 0.04 14.0 0.7 0.31 11.2 0.7 2.6 1 0 0 1 1 1 0 DUP family AAA_22 PF13401.6 KFL61421.1 - 0.051 13.9 0.9 3.2 8.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF720 PF05302.11 KFL61421.1 - 0.056 13.3 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) AAA_21 PF13304.6 KFL61421.1 - 0.059 13.2 0.5 0.55 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KFL61421.1 - 0.1 12.3 0.1 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 KFL61422.1 - 1.8e-86 290.2 31.4 7.1e-46 157.1 12.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61422.1 - 4.2e-28 98.6 0.1 2.9e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KFL61422.1 - 3.2e-06 27.2 1.6 0.031 14.3 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFL61422.1 - 4.9e-06 26.6 0.6 0.0015 18.5 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KFL61422.1 - 0.0012 18.3 0.2 7.7 5.9 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 KFL61422.1 - 0.0018 18.4 0.7 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KFL61422.1 - 0.002 17.8 0.3 1.4 8.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFL61422.1 - 0.003 18.1 0.4 0.28 11.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFL61422.1 - 0.0093 16.4 0.1 5.6 7.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KFL61422.1 - 0.013 15.6 2.4 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KFL61422.1 - 0.019 15.4 0.0 1.5 9.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KFL61422.1 - 0.02 15.1 4.0 15 5.9 0.0 4.3 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUP PF00674.18 KFL61422.1 - 0.04 14.0 0.7 0.31 11.2 0.7 2.6 1 0 0 1 1 1 0 DUP family AAA_22 PF13401.6 KFL61422.1 - 0.051 13.9 0.9 3.2 8.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF720 PF05302.11 KFL61422.1 - 0.056 13.3 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) AAA_21 PF13304.6 KFL61422.1 - 0.059 13.2 0.5 0.55 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KFL61422.1 - 0.1 12.3 0.1 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 KFL61423.1 - 1.8e-86 290.2 31.4 7.1e-46 157.1 12.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61423.1 - 4.2e-28 98.6 0.1 2.9e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KFL61423.1 - 3.2e-06 27.2 1.6 0.031 14.3 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFL61423.1 - 4.9e-06 26.6 0.6 0.0015 18.5 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KFL61423.1 - 0.0012 18.3 0.2 7.7 5.9 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 KFL61423.1 - 0.0018 18.4 0.7 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KFL61423.1 - 0.002 17.8 0.3 1.4 8.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFL61423.1 - 0.003 18.1 0.4 0.28 11.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFL61423.1 - 0.0093 16.4 0.1 5.6 7.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KFL61423.1 - 0.013 15.6 2.4 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KFL61423.1 - 0.019 15.4 0.0 1.5 9.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KFL61423.1 - 0.02 15.1 4.0 15 5.9 0.0 4.3 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUP PF00674.18 KFL61423.1 - 0.04 14.0 0.7 0.31 11.2 0.7 2.6 1 0 0 1 1 1 0 DUP family AAA_22 PF13401.6 KFL61423.1 - 0.051 13.9 0.9 3.2 8.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF720 PF05302.11 KFL61423.1 - 0.056 13.3 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) AAA_21 PF13304.6 KFL61423.1 - 0.059 13.2 0.5 0.55 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KFL61423.1 - 0.1 12.3 0.1 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 KFL61424.1 - 1.8e-86 290.2 31.4 7.1e-46 157.1 12.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61424.1 - 4.2e-28 98.6 0.1 2.9e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KFL61424.1 - 3.2e-06 27.2 1.6 0.031 14.3 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFL61424.1 - 4.9e-06 26.6 0.6 0.0015 18.5 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KFL61424.1 - 0.0012 18.3 0.2 7.7 5.9 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 KFL61424.1 - 0.0018 18.4 0.7 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KFL61424.1 - 0.002 17.8 0.3 1.4 8.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFL61424.1 - 0.003 18.1 0.4 0.28 11.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFL61424.1 - 0.0093 16.4 0.1 5.6 7.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KFL61424.1 - 0.013 15.6 2.4 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KFL61424.1 - 0.019 15.4 0.0 1.5 9.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KFL61424.1 - 0.02 15.1 4.0 15 5.9 0.0 4.3 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUP PF00674.18 KFL61424.1 - 0.04 14.0 0.7 0.31 11.2 0.7 2.6 1 0 0 1 1 1 0 DUP family AAA_22 PF13401.6 KFL61424.1 - 0.051 13.9 0.9 3.2 8.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF720 PF05302.11 KFL61424.1 - 0.056 13.3 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) AAA_21 PF13304.6 KFL61424.1 - 0.059 13.2 0.5 0.55 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KFL61424.1 - 0.1 12.3 0.1 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 KFL61425.1 - 1.9e-61 208.1 18.5 1.7e-40 139.4 10.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61425.1 - 9.4e-19 68.3 0.0 2.2e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFL61425.1 - 0.00045 20.2 0.1 0.0012 18.8 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KFL61425.1 - 0.0062 16.6 0.2 0.025 14.7 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 KFL61425.1 - 0.016 14.6 0.0 5.9 6.3 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFL61425.1 - 0.034 14.6 0.0 0.22 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUP PF00674.18 KFL61425.1 - 0.038 14.1 0.7 0.24 11.6 0.7 2.4 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61425.1 - 0.042 13.7 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Dynamin_N PF00350.23 KFL61425.1 - 0.05 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 KFL61425.1 - 0.072 13.3 0.8 12 6.2 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2754 PF10953.8 KFL61425.1 - 0.084 13.1 0.0 0.42 10.9 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) AAA_21 PF13304.6 KFL61425.1 - 0.17 11.6 0.0 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 KFL61426.1 - 1.9e-61 208.1 18.5 1.7e-40 139.4 10.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61426.1 - 9.4e-19 68.3 0.0 2.2e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFL61426.1 - 0.00045 20.2 0.1 0.0012 18.8 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KFL61426.1 - 0.0062 16.6 0.2 0.025 14.7 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 KFL61426.1 - 0.016 14.6 0.0 5.9 6.3 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFL61426.1 - 0.034 14.6 0.0 0.22 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUP PF00674.18 KFL61426.1 - 0.038 14.1 0.7 0.24 11.6 0.7 2.4 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61426.1 - 0.042 13.7 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Dynamin_N PF00350.23 KFL61426.1 - 0.05 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 KFL61426.1 - 0.072 13.3 0.8 12 6.2 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2754 PF10953.8 KFL61426.1 - 0.084 13.1 0.0 0.42 10.9 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) AAA_21 PF13304.6 KFL61426.1 - 0.17 11.6 0.0 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 KFL61427.1 - 1.9e-61 208.1 18.5 1.7e-40 139.4 10.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61427.1 - 9.4e-19 68.3 0.0 2.2e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFL61427.1 - 0.00045 20.2 0.1 0.0012 18.8 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KFL61427.1 - 0.0062 16.6 0.2 0.025 14.7 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 KFL61427.1 - 0.016 14.6 0.0 5.9 6.3 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFL61427.1 - 0.034 14.6 0.0 0.22 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUP PF00674.18 KFL61427.1 - 0.038 14.1 0.7 0.24 11.6 0.7 2.4 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61427.1 - 0.042 13.7 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Dynamin_N PF00350.23 KFL61427.1 - 0.05 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 KFL61427.1 - 0.072 13.3 0.8 12 6.2 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2754 PF10953.8 KFL61427.1 - 0.084 13.1 0.0 0.42 10.9 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) AAA_21 PF13304.6 KFL61427.1 - 0.17 11.6 0.0 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 KFL61428.1 - 1.7e-58 198.4 17.3 1.7e-40 139.4 10.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61428.1 - 9.3e-19 68.3 0.0 2.2e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFL61428.1 - 0.00044 20.2 0.1 0.0011 18.9 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KFL61428.1 - 0.006 16.6 0.2 0.024 14.7 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 KFL61428.1 - 0.016 14.7 0.0 5.8 6.3 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFL61428.1 - 0.033 14.7 0.0 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUP PF00674.18 KFL61428.1 - 0.037 14.2 0.7 0.24 11.6 0.7 2.4 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61428.1 - 0.041 13.7 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Dynamin_N PF00350.23 KFL61428.1 - 0.049 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 KFL61428.1 - 0.07 13.4 0.8 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2754 PF10953.8 KFL61428.1 - 0.082 13.2 0.0 0.41 10.9 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) ABC_membrane PF00664.23 KFL61429.1 - 1.7e-58 198.4 17.3 1.7e-40 139.4 10.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61429.1 - 9.3e-19 68.3 0.0 2.2e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFL61429.1 - 0.00044 20.2 0.1 0.0011 18.9 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KFL61429.1 - 0.006 16.6 0.2 0.024 14.7 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 KFL61429.1 - 0.016 14.7 0.0 5.8 6.3 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFL61429.1 - 0.033 14.7 0.0 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUP PF00674.18 KFL61429.1 - 0.037 14.2 0.7 0.24 11.6 0.7 2.4 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61429.1 - 0.041 13.7 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Dynamin_N PF00350.23 KFL61429.1 - 0.049 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 KFL61429.1 - 0.07 13.4 0.8 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2754 PF10953.8 KFL61429.1 - 0.082 13.2 0.0 0.41 10.9 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) ABC_membrane PF00664.23 KFL61430.1 - 1.7e-58 198.4 17.3 1.7e-40 139.4 10.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61430.1 - 9.3e-19 68.3 0.0 2.2e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFL61430.1 - 0.00044 20.2 0.1 0.0011 18.9 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KFL61430.1 - 0.006 16.6 0.2 0.024 14.7 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 KFL61430.1 - 0.016 14.7 0.0 5.8 6.3 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFL61430.1 - 0.033 14.7 0.0 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUP PF00674.18 KFL61430.1 - 0.037 14.2 0.7 0.24 11.6 0.7 2.4 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61430.1 - 0.041 13.7 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Dynamin_N PF00350.23 KFL61430.1 - 0.049 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 KFL61430.1 - 0.07 13.4 0.8 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2754 PF10953.8 KFL61430.1 - 0.082 13.2 0.0 0.41 10.9 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) ABC_membrane PF00664.23 KFL61431.1 - 1.7e-58 198.4 17.3 1.7e-40 139.4 10.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61431.1 - 9.3e-19 68.3 0.0 2.2e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFL61431.1 - 0.00044 20.2 0.1 0.0011 18.9 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KFL61431.1 - 0.006 16.6 0.2 0.024 14.7 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 KFL61431.1 - 0.016 14.7 0.0 5.8 6.3 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFL61431.1 - 0.033 14.7 0.0 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUP PF00674.18 KFL61431.1 - 0.037 14.2 0.7 0.24 11.6 0.7 2.4 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61431.1 - 0.041 13.7 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Dynamin_N PF00350.23 KFL61431.1 - 0.049 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 KFL61431.1 - 0.07 13.4 0.8 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2754 PF10953.8 KFL61431.1 - 0.082 13.2 0.0 0.41 10.9 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) ABC_membrane PF00664.23 KFL61432.1 - 1.7e-58 198.4 17.3 1.7e-40 139.4 10.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61432.1 - 9.3e-19 68.3 0.0 2.2e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFL61432.1 - 0.00044 20.2 0.1 0.0011 18.9 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KFL61432.1 - 0.006 16.6 0.2 0.024 14.7 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 KFL61432.1 - 0.016 14.7 0.0 5.8 6.3 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFL61432.1 - 0.033 14.7 0.0 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUP PF00674.18 KFL61432.1 - 0.037 14.2 0.7 0.24 11.6 0.7 2.4 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61432.1 - 0.041 13.7 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Dynamin_N PF00350.23 KFL61432.1 - 0.049 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 KFL61432.1 - 0.07 13.4 0.8 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2754 PF10953.8 KFL61432.1 - 0.082 13.2 0.0 0.41 10.9 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) ABC_membrane PF00664.23 KFL61433.1 - 1.7e-58 198.4 17.3 1.7e-40 139.4 10.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFL61433.1 - 9.3e-19 68.3 0.0 2.2e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFL61433.1 - 0.00044 20.2 0.1 0.0011 18.9 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KFL61433.1 - 0.006 16.6 0.2 0.024 14.7 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 KFL61433.1 - 0.016 14.7 0.0 5.8 6.3 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFL61433.1 - 0.033 14.7 0.0 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUP PF00674.18 KFL61433.1 - 0.037 14.2 0.7 0.24 11.6 0.7 2.4 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 KFL61433.1 - 0.041 13.7 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Dynamin_N PF00350.23 KFL61433.1 - 0.049 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 KFL61433.1 - 0.07 13.4 0.8 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2754 PF10953.8 KFL61433.1 - 0.082 13.2 0.0 0.41 10.9 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) SKG6 PF08693.10 KFL61438.1 - 0.0053 16.1 0.8 0.0091 15.4 0.8 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain p450 PF00067.22 KFL61439.1 - 2e-23 82.9 0.0 2.3e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DEP PF00610.21 KFL61439.1 - 0.19 11.8 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) eIF3g PF12353.8 KFL61440.1 - 0.077 13.4 0.1 0.1 13.0 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G CDC27 PF09507.10 KFL61442.1 - 0.021 14.2 20.6 0.025 14.0 20.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 KFL61442.1 - 0.67 8.2 10.8 0.74 8.0 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 KFL61442.1 - 0.68 8.0 12.8 0.81 7.7 12.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Endostatin PF06482.11 KFL61442.1 - 1.1 8.7 6.8 1.2 8.5 6.8 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF913 PF06025.12 KFL61442.1 - 1.1 8.2 5.9 1.4 7.8 5.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.16 KFL61442.1 - 1.3 9.1 6.2 1.5 8.8 6.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mitofilin PF09731.9 KFL61442.1 - 2 7.1 23.2 0.67 8.7 20.5 1.5 2 0 0 2 2 2 0 Mitochondrial inner membrane protein GREB1 PF15782.5 KFL61442.1 - 2.9 4.9 9.9 3.1 4.8 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 KFL61442.1 - 4 7.2 16.7 5.8 6.7 16.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 KFL61442.1 - 7.8 5.2 9.3 9.4 4.9 9.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PARP PF00644.20 KFL61443.1 - 1.6e-59 200.8 0.1 3.3e-59 199.8 0.0 1.5 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KFL61443.1 - 3.3e-43 147.1 0.2 5.2e-43 146.4 0.2 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KFL61443.1 - 0.022 14.8 0.3 0.046 13.8 0.3 1.5 1 0 0 1 1 1 0 WGR domain Aminotran_1_2 PF00155.21 KFL61444.1 - 7.7e-86 288.5 0.0 1.3e-85 287.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFL61444.1 - 2.2e-06 26.5 0.0 4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KFL61444.1 - 1.4e-05 24.6 0.1 2.7e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KFL61444.1 - 0.0012 17.9 0.0 0.0022 17.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFL61444.1 - 0.022 14.1 0.6 0.062 12.6 0.5 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase NitrOD2 PF18550.1 KFL61444.1 - 0.093 12.9 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Nitrososphaera output domain 2 TehB PF03848.14 KFL61445.1 - 0.21 11.0 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB STE PF02200.16 KFL61447.1 - 4.3e-20 72.2 0.9 1.1e-17 64.4 1.8 2.4 1 1 1 2 2 2 2 STE like transcription factor zf-C2H2 PF00096.26 KFL61447.1 - 2.1e-11 43.6 10.8 6.1e-07 29.5 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFL61447.1 - 2.1e-09 37.4 4.2 2.1e-09 37.4 4.2 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFL61447.1 - 1.1e-07 32.1 8.8 0.0009 19.9 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFL61447.1 - 0.0024 17.8 0.3 0.0024 17.8 0.3 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFL61447.1 - 0.0062 16.8 0.3 0.11 12.9 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.10 KFL61447.1 - 0.027 15.1 2.1 0.07 13.8 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_9 PF14369.6 KFL61447.1 - 0.058 13.7 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon zf-Di19 PF05605.12 KFL61447.1 - 0.069 13.5 0.3 0.069 13.5 0.3 2.4 2 1 0 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 KFL61447.1 - 0.13 12.5 0.4 0.29 11.4 0.4 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-TRAF PF02176.18 KFL61447.1 - 0.27 12.0 2.9 0.48 11.1 2.9 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger GAGA PF09237.11 KFL61447.1 - 1.6 8.6 5.3 0.76 9.6 1.5 2.3 2 0 0 2 2 2 0 GAGA factor zf-C2HC_2 PF13913.6 KFL61447.1 - 1.9 8.5 4.3 4.9 7.2 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KFL61447.1 - 5.1 6.9 10.4 13 5.6 0.8 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Pkinase PF00069.25 KFL61451.1 - 2e-69 233.9 0.0 8.4e-69 231.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61451.1 - 1.7e-47 161.9 0.0 3.6e-47 160.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KFL61451.1 - 3.6e-28 97.8 0.0 6.8e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 KFL61451.1 - 4.3e-08 32.8 0.0 0.00022 20.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RA PF00788.23 KFL61451.1 - 7.2e-05 23.3 0.0 0.00014 22.4 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 KFL61451.1 - 0.0022 16.9 0.8 0.004 16.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFL61451.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MSA-2c PF12238.8 KFL61451.1 - 0.6 10.1 4.5 0.93 9.5 0.0 2.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Pkinase PF00069.25 KFL61452.1 - 1.4e-69 234.4 0.0 6.2e-69 232.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61452.1 - 1.5e-47 162.1 0.0 2.7e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KFL61452.1 - 3e-28 98.1 0.0 5.5e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 KFL61452.1 - 3e-08 33.3 0.0 0.00018 20.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RA PF00788.23 KFL61452.1 - 6e-05 23.6 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 KFL61452.1 - 0.0017 17.2 0.8 0.0031 16.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFL61452.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TORC_C PF12886.7 KFL61452.1 - 0.12 12.9 0.0 0.34 11.5 0.0 1.7 1 0 0 1 1 1 0 Transducer of regulated CREB activity, C terminus TPR_14 PF13428.6 KFL61453.1 - 5.3e-10 39.3 3.4 0.011 16.5 0.0 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFL61453.1 - 1.5e-09 37.2 0.2 0.035 14.2 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFL61453.1 - 2.1e-08 34.6 6.3 0.015 15.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFL61453.1 - 2.7e-07 30.3 5.4 0.038 14.2 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFL61453.1 - 1.1e-05 25.1 1.6 0.011 15.5 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFL61453.1 - 3.6e-05 23.8 0.0 2.6 8.6 0.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFL61453.1 - 0.00039 21.0 4.9 1.8 9.3 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFL61453.1 - 0.088 12.0 2.0 3.6 6.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFL61453.1 - 0.16 12.3 4.5 7.6 6.9 0.1 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFL61453.1 - 0.2 12.0 3.5 6 7.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFL61453.1 - 0.25 12.1 1.1 4.9 8.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Dimerisation PF08100.11 KFL61454.1 - 0.026 14.5 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_2 PF00891.18 KFL61455.1 - 1.3e-09 37.7 0.0 1.5e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KFL61455.1 - 0.072 12.5 0.0 0.081 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 KFL61455.1 - 0.081 12.5 0.0 0.094 12.3 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain GSH_synth_ATP PF03917.17 KFL61456.1 - 2.2e-85 286.7 0.0 2.5e-85 286.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KFL61456.1 - 7.9e-28 96.9 0.0 1.2e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Bestrophin PF01062.21 KFL61457.1 - 7e-26 91.3 0.0 1e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Aminotran_3 PF00202.21 KFL61458.1 - 6.7e-107 357.6 0.0 7.5e-107 357.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFL61458.1 - 0.006 15.8 0.0 0.0084 15.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Peroxin-3 PF04882.12 KFL61460.1 - 3.9e-59 200.9 0.3 4.6e-59 200.6 0.3 1.0 1 0 0 1 1 1 1 Peroxin-3 PUMA PF15826.5 KFL61461.1 - 0.44 10.7 4.9 0.84 9.8 4.9 1.4 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis zf-C4H2 PF10146.9 KFL61462.1 - 0.0077 16.6 6.2 0.019 15.3 6.2 1.6 1 0 0 1 1 1 1 Zinc finger-containing protein PRIMA1 PF16101.5 KFL61462.1 - 0.014 15.5 4.2 0.035 14.1 4.2 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SRP-alpha_N PF04086.13 KFL61462.1 - 2.8 7.8 13.6 0.21 11.5 4.9 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Endostatin PF06482.11 KFL61462.1 - 8.5 5.7 8.7 0.88 9.0 4.0 1.8 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin CAP_N PF01213.19 KFL61462.1 - 9.3 5.6 12.8 8.7 5.7 11.2 1.7 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ytp1 PF10355.9 KFL61463.1 - 3.7e-57 193.7 15.7 3.7e-57 193.7 15.7 2.4 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KFL61463.1 - 1e-31 108.8 3.2 1e-31 108.8 3.2 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF3180 PF11377.8 KFL61463.1 - 0.027 14.6 8.3 0.47 10.6 5.1 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF3180) ExoD PF06055.12 KFL61463.1 - 0.038 13.4 0.0 0.038 13.4 0.0 2.8 3 0 0 3 3 3 0 Exopolysaccharide synthesis, ExoD DUF973 PF06157.11 KFL61463.1 - 0.12 11.5 9.1 0.22 10.6 9.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF4225 PF13988.6 KFL61463.1 - 2.3 7.7 4.3 4.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Ytp1 PF10355.9 KFL61464.1 - 2.9e-57 194.0 15.9 2.9e-57 194.0 15.9 2.5 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KFL61464.1 - 6.9e-23 80.4 6.1 6.9e-23 80.4 6.1 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF973 PF06157.11 KFL61464.1 - 0.012 14.7 6.0 0.022 13.8 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3180 PF11377.8 KFL61464.1 - 0.02 15.1 8.3 0.35 11.0 5.1 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF3180) ExoD PF06055.12 KFL61464.1 - 0.029 13.7 0.0 0.029 13.7 0.0 2.5 3 0 0 3 3 3 0 Exopolysaccharide synthesis, ExoD DUF4225 PF13988.6 KFL61464.1 - 1.6 8.3 4.4 4 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Ytp1 PF10355.9 KFL61465.1 - 2.9e-57 194.0 15.9 2.9e-57 194.0 15.9 2.5 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KFL61465.1 - 6.9e-23 80.4 6.1 6.9e-23 80.4 6.1 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF973 PF06157.11 KFL61465.1 - 0.012 14.7 6.0 0.022 13.8 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3180 PF11377.8 KFL61465.1 - 0.02 15.1 8.3 0.35 11.0 5.1 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF3180) ExoD PF06055.12 KFL61465.1 - 0.029 13.7 0.0 0.029 13.7 0.0 2.5 3 0 0 3 3 3 0 Exopolysaccharide synthesis, ExoD DUF4225 PF13988.6 KFL61465.1 - 1.6 8.3 4.4 4 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Ytp1 PF10355.9 KFL61466.1 - 4e-71 239.5 18.9 1.6e-70 237.5 18.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) ExoD PF06055.12 KFL61466.1 - 0.0078 15.6 2.4 0.026 13.9 0.0 2.3 2 0 0 2 2 2 1 Exopolysaccharide synthesis, ExoD DUF973 PF06157.11 KFL61466.1 - 0.14 11.2 6.0 0.29 10.1 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF4225 PF13988.6 KFL61466.1 - 1.2 8.7 4.0 3.7 7.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) SdpI PF13630.6 KFL61466.1 - 3.7 7.8 16.4 12 6.1 0.7 4.8 5 0 0 5 5 5 0 SdpI/YhfL protein family Ytp1 PF10355.9 KFL61467.1 - 4e-71 239.5 18.9 1.6e-70 237.5 18.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) ExoD PF06055.12 KFL61467.1 - 0.0078 15.6 2.4 0.026 13.9 0.0 2.3 2 0 0 2 2 2 1 Exopolysaccharide synthesis, ExoD DUF973 PF06157.11 KFL61467.1 - 0.14 11.2 6.0 0.29 10.1 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF4225 PF13988.6 KFL61467.1 - 1.2 8.7 4.0 3.7 7.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) SdpI PF13630.6 KFL61467.1 - 3.7 7.8 16.4 12 6.1 0.7 4.8 5 0 0 5 5 5 0 SdpI/YhfL protein family Glycos_transf_2 PF00535.26 KFL61468.1 - 1.1e-23 83.9 0.1 1.8e-21 76.7 0.1 3.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFL61468.1 - 4.7e-05 23.4 0.0 0.19 11.6 0.0 3.1 2 1 1 3 3 3 2 Glycosyltransferase like family 2 Dicty_CAR PF05462.11 KFL61469.1 - 0.00016 20.9 7.3 0.00023 20.4 2.8 2.1 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KFL61469.1 - 0.0011 18.8 2.7 0.0026 17.6 2.7 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_2 PF00002.24 KFL61469.1 - 0.017 14.4 1.2 0.087 12.1 1.1 1.9 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) GPR_Gpa2_C PF11970.8 KFL61469.1 - 0.062 13.4 0.4 0.062 13.4 0.4 2.0 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF1174 PF06671.11 KFL61469.1 - 4.3 7.1 8.3 6.9 6.5 8.3 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1174) EST1_DNA_bind PF10373.9 KFL61470.1 - 6.4e-12 45.5 1.5 8e-10 38.7 0.6 2.5 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain Sec8_exocyst PF04048.14 KFL61473.1 - 0.0025 17.7 0.5 0.011 15.6 0.2 2.1 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Peptidase_M16 PF00675.20 KFL61474.1 - 5.2e-17 62.2 0.0 8.9e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFL61474.1 - 4.7e-12 46.3 0.0 7.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain E1-E2_ATPase PF00122.20 KFL61477.1 - 6.1e-48 162.7 5.0 6.1e-48 162.7 5.0 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KFL61477.1 - 1.7e-17 64.4 0.0 5.2e-17 62.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFL61477.1 - 2.3e-11 43.2 0.0 5e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFL61477.1 - 0.0016 18.5 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFL61477.1 - 0.005 16.6 0.1 0.005 16.6 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 KFL61477.1 - 0.092 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) O-antigen_lig PF13425.6 KFL61477.1 - 0.12 11.2 5.6 0.33 9.7 5.6 1.7 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Mak10 PF04112.13 KFL61480.1 - 4.9e-65 218.1 0.0 8.7e-65 217.3 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase SpecificRecomb PF10136.9 KFL61480.1 - 1e-05 24.1 0.1 1.3e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Site-specific recombinase Cofilin_ADF PF00241.20 KFL61481.1 - 1.2e-14 54.1 0.0 1.5e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cofilin_ADF PF00241.20 KFL61482.1 - 2.7e-22 78.9 0.0 3.1e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein COX4 PF02936.14 KFL61483.1 - 9e-46 155.3 0.3 1.2e-45 154.9 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 KFL61483.1 - 0.014 15.9 2.6 0.014 15.9 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1138 PF06592.13 KFL61483.1 - 0.093 12.8 0.0 0.32 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) DUF1104 PF06518.11 KFL61483.1 - 0.11 12.9 0.1 0.11 12.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) CBM_48 PF02922.18 KFL61484.1 - 3.2e-19 69.1 0.0 6.4e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KFL61484.1 - 7.4e-15 55.3 1.3 1.2e-11 44.8 0.2 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KFL61485.1 - 6.5e-26 90.6 0.1 1.8e-25 89.2 0.1 1.7 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain ATP-synt_ab PF00006.25 KFL61486.1 - 5.5e-62 209.2 0.0 9.2e-62 208.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFL61486.1 - 3.3e-21 75.6 3.1 9.9e-21 74.0 2.6 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 KFL61486.1 - 0.009 16.4 0.0 0.59 10.6 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KFL61486.1 - 0.011 15.6 0.6 0.031 14.2 0.0 2.0 3 0 0 3 3 3 0 RsgA GTPase NB-ARC PF00931.22 KFL61486.1 - 0.019 14.2 0.3 0.097 11.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KFL61486.1 - 0.026 14.4 0.0 0.079 12.9 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KFL61486.1 - 0.034 14.5 1.0 0.48 10.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFL61486.1 - 0.039 13.9 0.2 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 KFL61486.1 - 0.046 13.1 0.2 0.085 12.2 0.2 1.4 1 0 0 1 1 1 0 KaiC T3SS_ATPase_C PF18269.1 KFL61486.1 - 0.057 13.3 0.8 0.28 11.1 0.8 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RNA_helicase PF00910.22 KFL61486.1 - 0.078 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KFL61486.1 - 0.098 13.0 0.1 0.36 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 KFL61487.1 - 3.4e-62 209.9 0.0 5.4e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 KFL61487.1 - 0.0053 17.2 0.0 0.42 11.0 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KFL61487.1 - 0.0092 15.9 0.2 0.022 14.7 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 KFL61487.1 - 0.012 14.8 0.3 0.071 12.3 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KFL61487.1 - 0.016 15.2 0.0 0.054 13.4 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KFL61487.1 - 0.022 15.1 1.0 0.37 11.1 0.2 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab_N PF02874.23 KFL61487.1 - 0.024 15.2 0.7 0.11 13.0 0.5 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain NACHT PF05729.12 KFL61487.1 - 0.033 14.1 0.1 0.097 12.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 KFL61487.1 - 0.034 13.5 0.2 0.06 12.7 0.2 1.4 1 0 0 1 1 1 0 KaiC T3SS_ATPase_C PF18269.1 KFL61487.1 - 0.036 13.9 0.8 0.2 11.5 0.8 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RNA_helicase PF00910.22 KFL61487.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KFL61487.1 - 0.066 13.6 0.1 0.23 11.8 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain EF-hand_2 PF09068.11 KFL61488.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 EF hand Chromo PF00385.24 KFL61490.1 - 1.9e-08 34.1 0.0 4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KFL61490.1 - 0.0034 17.5 0.0 0.0071 16.5 0.0 1.5 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Ras PF00071.22 KFL61491.1 - 1.2e-62 210.2 0.3 1.4e-62 210.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL61491.1 - 2.1e-35 121.6 0.2 2.8e-35 121.1 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL61491.1 - 1.5e-13 50.6 0.1 1.8e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFL61491.1 - 8.7e-08 32.3 0.1 1.4e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFL61491.1 - 2.5e-05 24.2 1.7 0.014 15.3 0.2 2.2 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFL61491.1 - 0.00014 21.5 0.1 0.00058 19.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFL61491.1 - 0.00032 20.1 0.1 0.00052 19.4 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KFL61491.1 - 0.0015 18.8 0.0 0.0086 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KFL61491.1 - 0.0058 16.1 0.0 0.008 15.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KFL61491.1 - 0.011 15.8 0.1 0.031 14.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFL61491.1 - 0.011 16.2 0.1 0.017 15.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_32 PF13654.6 KFL61491.1 - 0.011 14.5 0.0 0.3 9.8 0.0 2.4 1 1 2 3 3 3 0 AAA domain AAA_16 PF13191.6 KFL61491.1 - 0.016 15.6 0.0 0.021 15.2 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFL61491.1 - 0.021 14.5 0.1 0.045 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KFL61491.1 - 0.025 14.0 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein SpoIIID PF12116.8 KFL61491.1 - 0.025 14.6 0.1 0.6 10.2 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_29 PF13555.6 KFL61491.1 - 0.054 13.2 0.0 0.42 10.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.23 KFL61491.1 - 0.069 12.2 0.0 0.17 11.0 0.0 1.7 1 1 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 KFL61491.1 - 0.078 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 KFL61491.1 - 0.079 12.5 0.1 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.6 KFL61491.1 - 0.08 12.7 0.6 0.11 12.3 0.5 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KFL61491.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KFL61491.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation UFD1 PF03152.14 KFL61495.1 - 1.6e-75 252.3 0.0 2.2e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 KFL61495.1 - 0.049 13.4 0.0 0.77 9.6 0.0 2.2 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 UFD1 PF03152.14 KFL61496.1 - 6.3e-37 126.7 0.0 8.8e-37 126.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 KFL61496.1 - 0.023 14.5 0.0 0.51 10.2 0.0 2.3 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Pkinase PF00069.25 KFL61500.1 - 1.8e-32 112.7 2.1 2.3e-31 109.1 2.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61500.1 - 1.9e-28 99.5 0.0 3.9e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFL61500.1 - 4.5e-24 84.6 0.0 4.5e-24 84.6 0.0 2.6 3 0 0 3 3 3 1 P21-Rho-binding domain PH_11 PF15413.6 KFL61500.1 - 2.4e-15 56.8 0.1 7e-15 55.3 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFL61500.1 - 0.00014 22.4 0.1 0.00032 21.2 0.1 1.7 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 KFL61500.1 - 0.0036 16.3 0.0 0.0075 15.3 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFL61500.1 - 0.01 14.9 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 KIND PF16474.5 KFL61500.1 - 0.032 14.1 0.0 0.096 12.6 0.0 1.8 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain PIN_11 PF18479.1 KFL61503.1 - 0.079 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 PIN like domain Adap_comp_sub PF00928.21 KFL61505.1 - 8.7e-84 281.0 0.0 1.4e-83 280.3 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFL61505.1 - 6.8e-08 32.5 0.4 1.1e-07 31.8 0.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KFL61505.1 - 0.13 11.6 0.0 0.32 10.4 0.0 1.5 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.21 KFL61506.1 - 8.4e-84 281.0 0.0 1.4e-83 280.3 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFL61506.1 - 3.9e-08 33.4 0.2 6.5e-08 32.6 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KFL61506.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.5 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.21 KFL61507.1 - 5.6e-84 281.6 0.0 7.1e-84 281.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 KFL61507.1 - 0.085 12.3 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.6 KFL61508.1 - 1.9e-14 53.9 0.0 3.3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFL61508.1 - 0.012 16.2 0.0 0.037 14.7 0.0 1.8 1 1 0 1 1 1 0 Ribonuclease III domain Sdh_cyt PF01127.22 KFL61510.1 - 3e-24 85.4 4.2 4.2e-24 84.9 4.2 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NMO PF03060.15 KFL61511.1 - 8.9e-31 107.5 0.5 2e-30 106.3 0.5 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFL61511.1 - 8.2e-06 25.0 0.6 1.3e-05 24.4 0.4 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KFL61511.1 - 0.00096 18.3 0.1 0.0013 17.9 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 KFL61511.1 - 0.013 14.7 0.1 0.03 13.5 0.0 1.5 1 1 1 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Hydrophobin PF01185.18 KFL61512.1 - 1.2e-06 29.1 10.1 2.1e-06 28.2 10.1 1.4 1 0 0 1 1 1 1 Fungal hydrophobin ATP_sub_h PF10775.9 KFL61512.1 - 0.0028 17.6 0.2 0.0068 16.4 0.2 1.6 1 0 0 1 1 1 1 ATP synthase complex subunit h MCM PF00493.23 KFL61513.1 - 2.2e-104 347.4 0.1 2.8e-104 347.1 0.1 1.1 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFL61513.1 - 8.2e-22 77.4 0.2 1.3e-21 76.7 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 KFL61513.1 - 1.5e-07 31.0 0.0 4.5e-05 22.9 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFL61513.1 - 7.7e-06 25.9 0.0 1.5e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFL61513.1 - 0.00019 21.3 0.1 0.001 18.9 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFL61513.1 - 0.0053 16.5 0.1 0.081 12.6 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain MCM_lid PF17855.1 KFL61514.1 - 5.2e-24 84.5 0.7 1.1e-23 83.4 0.7 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_lid_7 PF17867.1 KFL61514.1 - 0.00036 20.7 0.1 0.00054 20.1 0.1 1.2 1 0 0 1 1 1 1 Midasin AAA lid domain Imm35 PF15567.6 KFL61514.1 - 0.033 14.4 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 35 B56 PF01603.20 KFL61515.1 - 5.8e-54 183.7 0.1 7.2e-54 183.3 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Dynamin_N PF00350.23 KFL61515.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Dynamin family B56 PF01603.20 KFL61516.1 - 5.9e-61 206.7 0.6 6.9e-61 206.5 0.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KFL61516.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.4 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal B56 PF01603.20 KFL61517.1 - 8e-09 35.0 0.3 9.7e-09 34.7 0.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) TFIIA PF03153.13 KFL61521.1 - 0.0035 17.4 49.7 0.16 11.9 32.0 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 KFL61521.1 - 0.23 9.7 45.5 0.63 8.2 22.7 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 MMR1 PF08505.10 KFL61521.1 - 0.43 10.8 23.0 0.087 13.1 9.5 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Macoilin PF09726.9 KFL61521.1 - 1.1 7.7 14.0 1.1 7.7 6.2 2.1 2 0 0 2 2 2 0 Macoilin family Spt20 PF12090.8 KFL61521.1 - 1.4 8.4 48.2 0.53 9.9 28.7 2.5 2 0 0 2 2 2 0 Spt20 family NST1 PF13945.6 KFL61521.1 - 3.1 7.9 25.3 1.3 9.1 12.8 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator Presenilin PF01080.17 KFL61521.1 - 4.9 5.8 23.3 0.4 9.4 10.5 2.2 2 0 0 2 2 2 0 Presenilin CiPC PF15800.5 KFL61521.1 - 6.4 6.4 36.6 0.93 9.2 15.8 2.1 2 0 0 2 2 2 0 Clock interacting protein circadian SPX PF03105.19 KFL61521.1 - 9.9 6.0 24.4 2.4 8.0 8.0 2.1 2 0 0 2 2 2 0 SPX domain eIF-5a PF01287.20 KFL61523.1 - 4.9e-05 23.3 0.1 9.3e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold eIF-5a PF01287.20 KFL61524.1 - 4.9e-05 23.3 0.1 9.3e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold eIF-5a PF01287.20 KFL61525.1 - 2.8e-05 24.2 0.1 5.7e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Sulfatase PF00884.23 KFL61527.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Sulfatase CPSase_L_D2 PF02786.17 KFL61528.1 - 6.7e-74 247.9 0.0 9.7e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KFL61528.1 - 1.8e-36 124.5 0.0 3.9e-36 123.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFL61528.1 - 5.3e-15 55.0 3.5 6.3e-15 54.8 2.1 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFL61528.1 - 1.4e-09 37.8 0.0 3.4e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFL61528.1 - 1.7e-08 34.2 0.0 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KFL61528.1 - 9.6e-06 25.3 0.3 0.1 12.5 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Biotin_carb_N PF00289.22 KFL61528.1 - 2.3e-05 24.9 0.0 6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain ATP-grasp_3 PF02655.14 KFL61528.1 - 0.00037 20.6 0.0 0.00079 19.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KFL61528.1 - 0.0012 19.6 0.2 0.73 10.6 0.0 2.8 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.19 KFL61528.1 - 0.0021 17.8 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 KFL61528.1 - 0.0075 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 KFL61528.1 - 0.011 15.6 0.4 0.029 14.3 0.2 1.8 2 0 0 2 2 2 0 Glycine cleavage H-protein ATP-grasp_4 PF13535.6 KFL61528.1 - 0.014 15.0 0.0 0.056 13.0 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain HlyD_D23 PF16576.5 KFL61528.1 - 0.055 12.7 0.1 3.3 6.9 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 KFL61528.1 - 0.14 11.8 0.0 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.17 KFL61529.1 - 6.6e-74 247.9 0.0 9.5e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KFL61529.1 - 1.8e-36 124.5 0.0 3.8e-36 123.5 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFL61529.1 - 1.1e-12 47.6 3.9 1.3e-12 47.3 2.4 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFL61529.1 - 1.4e-09 37.8 0.0 3.3e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFL61529.1 - 1.7e-08 34.2 0.0 3.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_carb_N PF00289.22 KFL61529.1 - 2.3e-05 24.9 0.0 6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain ATP-grasp_3 PF02655.14 KFL61529.1 - 0.00036 20.6 0.0 0.00078 19.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KFL61529.1 - 0.002 17.9 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 KFL61529.1 - 0.0073 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp Biotin_lipoyl_2 PF13533.6 KFL61529.1 - 0.01 15.7 0.2 0.087 12.7 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.19 KFL61529.1 - 0.012 15.5 0.4 0.033 14.1 0.2 1.8 2 0 0 2 2 2 0 Glycine cleavage H-protein ATP-grasp_4 PF13535.6 KFL61529.1 - 0.014 15.0 0.0 0.056 13.0 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain RimK PF08443.11 KFL61529.1 - 0.13 11.9 0.0 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.17 KFL61530.1 - 5.6e-74 248.2 0.0 8.1e-74 247.7 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KFL61530.1 - 1.5e-36 124.8 0.0 3.4e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFL61530.1 - 4.5e-15 55.2 3.5 5.6e-15 54.9 2.1 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFL61530.1 - 1.2e-09 38.0 0.0 2.9e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFL61530.1 - 1.4e-08 34.5 0.0 2.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KFL61530.1 - 8.2e-06 25.6 0.3 0.09 12.6 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KFL61530.1 - 0.0003 20.9 0.0 0.00067 19.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KFL61530.1 - 0.00091 19.9 0.2 0.66 10.7 0.0 2.9 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.19 KFL61530.1 - 0.0018 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.19 KFL61530.1 - 0.0087 16.0 0.3 0.026 14.4 0.2 1.8 2 0 0 2 2 2 1 Glycine cleavage H-protein ATP-grasp_4 PF13535.6 KFL61530.1 - 0.012 15.3 0.0 0.05 13.2 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KFL61530.1 - 0.028 13.7 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 KFL61530.1 - 0.044 13.0 0.1 3 7.0 0.0 2.5 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 KFL61530.1 - 0.12 12.0 0.0 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Acyl-CoA_dh_1 PF00441.24 KFL61531.1 - 4.5e-40 137.3 0.4 8e-40 136.5 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFL61531.1 - 9.3e-27 93.1 0.1 1.8e-26 92.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFL61531.1 - 9e-24 84.3 0.3 1.8e-23 83.3 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFL61531.1 - 2.7e-15 56.8 0.0 4.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KFL61531.1 - 0.00014 21.6 0.4 0.00037 20.3 0.4 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_1 PF00441.24 KFL61532.1 - 3.9e-40 137.5 0.4 6.8e-40 136.7 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFL61532.1 - 8.7e-27 93.2 0.1 1.5e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFL61532.1 - 2.3e-15 57.0 0.0 3.7e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFL61532.1 - 8.6e-13 48.9 0.0 1.8e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 KFL61532.1 - 0.00012 21.8 0.5 0.00033 20.4 0.5 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Pox_L5 PF04872.13 KFL61532.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus L5 protein family Abhydrolase_1 PF00561.20 KFL61533.1 - 4.1e-20 72.5 0.1 4.1e-19 69.2 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 KFL61533.1 - 7e-05 22.6 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KFL61533.1 - 0.00091 18.6 0.0 0.092 12.0 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KFL61533.1 - 0.048 13.4 0.1 9.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.9 KFL61534.1 - 2.2e-27 95.1 6.7 2.8e-27 94.8 6.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 KFL61534.1 - 0.0034 17.3 10.1 0.099 12.7 1.6 2.7 1 1 2 3 3 3 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KFL61534.1 - 0.011 15.7 4.7 1.4 9.0 0.5 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COBRA PF04833.15 KFL61534.1 - 0.017 15.0 0.6 0.022 14.7 0.6 1.1 1 0 0 1 1 1 0 COBRA-like protein PAN_3 PF08277.12 KFL61534.1 - 0.023 14.5 0.3 0.044 13.6 0.3 1.4 1 0 0 1 1 1 0 PAN-like domain DDOST_48kD PF03345.14 KFL61535.1 - 7.2e-93 311.7 0.0 8.6e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta GST_N_3 PF13417.6 KFL61538.1 - 0.0018 18.7 0.0 0.0039 17.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFL61538.1 - 0.0079 16.2 0.8 0.06 13.4 0.8 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFL61538.1 - 0.008 16.4 0.0 0.053 13.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFL61538.1 - 0.029 15.1 0.0 0.054 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KFL61539.1 - 1.4e-06 28.3 0.5 2.8e-06 27.3 0.2 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFL61539.1 - 2.1e-06 27.8 0.0 3.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFL61539.1 - 0.0016 18.8 0.0 0.0035 17.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFL61539.1 - 0.022 15.0 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFL61539.1 - 0.024 15.4 0.0 0.047 14.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF436 PF04260.12 KFL61541.1 - 0.073 12.7 0.0 0.88 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF436) Mito_carr PF00153.27 KFL61543.1 - 1.7e-30 104.8 9.2 1.6e-14 53.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WSC PF01822.19 KFL61544.1 - 5e-08 33.0 10.1 5e-08 33.0 10.1 2.4 2 1 0 2 2 2 1 WSC domain Apt1 PF10351.9 KFL61544.1 - 0.0018 17.2 2.9 0.002 17.1 2.9 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain SPX PF03105.19 KFL61544.1 - 0.0021 18.1 4.7 0.0022 18.0 4.7 1.1 1 0 0 1 1 1 1 SPX domain Podoplanin PF05808.11 KFL61544.1 - 0.0078 16.3 10.1 0.015 15.4 10.1 1.4 1 0 0 1 1 1 1 Podoplanin Macoilin PF09726.9 KFL61544.1 - 0.0084 14.7 3.0 0.0089 14.6 3.0 1.1 1 0 0 1 1 1 1 Macoilin family FixQ PF05545.11 KFL61544.1 - 0.047 13.7 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ SOG2 PF10428.9 KFL61544.1 - 1.5 8.0 20.2 2.2 7.4 20.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 KFL61544.1 - 4.2 5.9 12.8 4.5 5.8 12.8 1.1 1 0 0 1 1 1 0 Hamartin protein AAA_12 PF13087.6 KFL61547.1 - 5.8e-38 130.5 0.1 1.8e-37 128.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFL61547.1 - 5e-25 88.8 0.0 1.8e-24 87.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFL61547.1 - 1e-10 42.1 0.0 3.8e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFL61547.1 - 1.9e-10 40.8 0.0 1.7e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KFL61547.1 - 1.8e-07 31.1 0.1 0.00028 20.7 0.0 3.4 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KFL61547.1 - 0.00047 20.2 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KFL61547.1 - 0.0005 19.6 0.0 0.00099 18.6 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DEAD PF00270.29 KFL61547.1 - 0.00066 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KFL61547.1 - 0.0054 16.0 0.4 0.39 9.9 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 KFL61547.1 - 0.085 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Helicase_RecD PF05127.14 KFL61547.1 - 0.088 12.7 0.0 0.78 9.6 0.0 2.1 2 0 0 2 2 2 0 Helicase UvrD-helicase PF00580.21 KFL61547.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA PF00004.29 KFL61547.1 - 0.57 10.6 1.8 7.9 6.9 0.7 2.8 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Peptidase_M36 PF02128.15 KFL61548.1 - 1.3e-128 429.3 0.3 1.9e-128 428.8 0.3 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KFL61548.1 - 1.1e-16 60.4 2.9 1.1e-16 60.4 2.9 2.3 3 0 0 3 3 3 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KFL61548.1 - 0.0011 18.8 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M36 PF02128.15 KFL61549.1 - 4.7e-156 519.6 0.2 5.6e-156 519.4 0.2 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 KFL61549.1 - 0.00012 22.0 0.0 0.00034 20.5 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Aa_trans PF01490.18 KFL61550.1 - 3.9e-84 282.7 13.9 5.9e-84 282.1 13.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.10 KFL61550.1 - 0.082 11.1 3.4 0.14 10.3 3.4 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Abhydrolase_9_N PF15420.6 KFL61550.1 - 1.3 9.0 10.5 0.8 9.7 0.5 3.5 4 0 0 4 4 4 0 Alpha/beta-hydrolase family N-terminus DUF2417 PF10329.9 KFL61550.1 - 1.5 8.1 9.5 22 4.3 0.3 4.1 4 0 0 4 4 4 0 Region of unknown function (DUF2417) Aa_trans PF01490.18 KFL61551.1 - 1e-58 199.0 5.2 1.8e-58 198.2 5.2 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_9_N PF15420.6 KFL61551.1 - 0.014 15.4 4.0 0.44 10.5 0.4 2.9 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus DUF2417 PF10329.9 KFL61551.1 - 1.1 8.7 5.1 16 4.8 0.3 3.2 3 0 0 3 3 3 0 Region of unknown function (DUF2417) Herpes_UL49_1 PF03117.14 KFL61552.1 - 0.055 12.7 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 UL49 family Laminin_G_3 PF13385.6 KFL61554.1 - 4.2e-07 30.2 0.0 7.1e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_S8 PF00082.22 KFL61555.1 - 2.9e-39 135.1 3.8 4e-39 134.7 3.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFL61555.1 - 3e-21 75.9 0.3 6.9e-21 74.7 0.3 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Metallophos PF00149.28 KFL61556.1 - 2.8e-37 129.2 0.6 6.9e-37 127.9 0.2 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 KFL61556.1 - 0.11 12.3 0.6 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) SAT PF16073.5 KFL61557.1 - 0.018 14.8 0.0 0.022 14.5 0.0 1.0 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF444 PF04285.12 KFL61557.1 - 0.086 11.9 0.6 0.25 10.4 0.2 1.5 1 1 0 2 2 2 0 Protein of unknown function (DUF444) SHE3 PF17078.5 KFL61558.1 - 0.02 14.6 0.3 0.024 14.4 0.3 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Voldacs PF03517.13 KFL61559.1 - 4.7e-29 101.3 0.6 4.7e-29 101.3 0.6 2.0 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling LIP PF03583.14 KFL61560.1 - 1.6e-21 76.9 0.0 2.1e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase LIP PF03583.14 KFL61561.1 - 1.2e-38 133.1 2.7 1.7e-38 132.6 2.7 1.1 1 0 0 1 1 1 1 Secretory lipase Proteasome PF00227.26 KFL61564.1 - 9.3e-45 152.5 0.0 1.2e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Terminase_5 PF06056.12 KFL61564.1 - 0.047 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-CHY PF05495.12 KFL61565.1 - 1.4e-11 44.7 19.1 2.6e-11 43.8 19.1 1.4 1 0 0 1 1 1 1 CHY zinc finger zinc_ribbon_9 PF14369.6 KFL61565.1 - 0.068 13.4 7.4 1.4 9.3 7.0 2.6 1 1 1 2 2 2 0 zinc-ribbon Zn-ribbon_8 PF09723.10 KFL61565.1 - 0.87 9.8 13.5 3.7 7.7 6.4 2.6 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 KFL61565.1 - 4.7 7.2 14.2 2.6 8.1 0.1 3.4 3 1 0 3 3 3 0 zinc-ribbon domain zf-CHY PF05495.12 KFL61566.1 - 1.7e-06 28.4 9.3 3.3e-06 27.5 9.3 1.4 1 0 0 1 1 1 1 CHY zinc finger RNA_POL_M_15KD PF02150.16 KFL61566.1 - 0.0033 17.3 3.5 3.2 7.7 0.0 3.3 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit zinc_ribbon_9 PF14369.6 KFL61566.1 - 0.024 14.9 1.0 0.024 14.9 1.0 2.4 1 1 0 2 2 2 0 zinc-ribbon zf-RRPl_C4 PF17026.5 KFL61566.1 - 0.062 13.4 5.0 0.036 14.2 2.2 1.9 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type MCR PF18509.1 KFL61566.1 - 0.25 11.0 0.4 0.25 11.0 0.4 2.7 3 0 0 3 3 3 0 Magnetochrome domain Zn-ribbon_8 PF09723.10 KFL61566.1 - 0.9 9.7 13.5 3.1 8.0 6.4 2.3 1 1 1 2 2 2 0 Zinc ribbon domain C1_4 PF07975.12 KFL61566.1 - 0.92 9.8 12.0 2.4 8.5 0.5 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 KFL61566.1 - 1.1 9.2 12.2 2.2 8.3 0.1 3.1 3 1 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 KFL61566.1 - 3.3 7.8 10.8 0.48 10.5 4.8 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DiS_P_DiS PF06750.13 KFL61566.1 - 8 6.7 6.1 5.5 7.2 1.8 2.0 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain ERG4_ERG24 PF01222.17 KFL61567.1 - 2.8e-136 454.7 11.4 3.2e-136 454.5 11.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KFL61567.1 - 5.1e-05 22.9 0.1 0.00016 21.3 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ANAPC4_WD40 PF12894.7 KFL61568.1 - 0.093 13.0 0.0 9.4 6.6 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFL61568.1 - 9 6.9 7.8 22 5.7 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain ANAPC4_WD40 PF12894.7 KFL61569.1 - 0.056 13.7 0.0 7.4 6.9 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFL61569.1 - 0.12 12.9 2.1 18 6.0 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain ANAPC4_WD40 PF12894.7 KFL61570.1 - 0.043 14.1 0.0 6.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFL61570.1 - 0.081 13.4 2.1 15 6.2 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain Arb2 PF09757.9 KFL61571.1 - 1e-100 336.2 5.7 1.2e-100 336.0 5.7 1.0 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KFL61571.1 - 0.0013 18.2 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain DUF1957 PF09210.11 KFL61571.1 - 0.029 14.7 0.2 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1957) Hist_deacetyl PF00850.19 KFL61572.1 - 0.0029 17.1 0.0 0.1 12.0 0.0 2.1 2 0 0 2 2 2 2 Histone deacetylase domain Gp_dh_C PF02800.20 KFL61573.1 - 4.3e-71 237.6 0.0 6.4e-71 237.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFL61573.1 - 9.1e-38 128.7 0.2 2.3e-37 127.4 0.1 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KFL61573.1 - 0.0013 18.8 0.0 0.0077 16.3 0.0 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KFL61573.1 - 0.077 12.4 0.0 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KFL61573.1 - 0.086 13.7 0.0 6.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Gp_dh_C PF02800.20 KFL61574.1 - 3.1e-71 238.1 0.0 4.5e-71 237.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFL61574.1 - 8.7e-18 64.5 0.1 2.6e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KFL61575.1 - 3.1e-71 238.1 0.0 4.5e-71 237.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFL61575.1 - 8.7e-18 64.5 0.1 2.6e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KFL61576.1 - 3.1e-71 238.1 0.0 4.5e-71 237.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFL61576.1 - 8.7e-18 64.5 0.1 2.6e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KFL61577.1 - 3.1e-71 238.1 0.0 4.5e-71 237.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFL61577.1 - 8.7e-18 64.5 0.1 2.6e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KFL61578.1 - 3.1e-71 238.1 0.0 4.5e-71 237.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFL61578.1 - 8.7e-18 64.5 0.1 2.6e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KFL61579.1 - 3.1e-71 238.1 0.0 4.5e-71 237.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFL61579.1 - 8.7e-18 64.5 0.1 2.6e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KFL61580.1 - 3.1e-71 238.1 0.0 4.5e-71 237.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFL61580.1 - 8.7e-18 64.5 0.1 2.6e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KFL61581.1 - 6.1e-54 181.9 0.0 1e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFL61581.1 - 9.7e-38 128.6 0.1 1.7e-37 127.8 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KFL61581.1 - 0.001 19.2 0.0 0.0059 16.7 0.0 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KFL61581.1 - 0.058 12.8 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KFL61581.1 - 0.082 13.7 0.1 5.4 7.9 0.0 2.5 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold R3H PF01424.22 KFL61583.1 - 4.3e-10 39.4 0.0 7.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 R3H domain SUIM_assoc PF16619.5 KFL61583.1 - 0.012 15.6 1.6 0.012 15.6 1.6 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Peptidase_M19 PF01244.21 KFL61584.1 - 4.3e-106 354.7 0.0 5.2e-106 354.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Peptidase_M19 PF01244.21 KFL61585.1 - 2.4e-89 299.7 0.2 2.7e-89 299.5 0.2 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Rep_fac_C PF08542.11 KFL61586.1 - 4.3e-16 59.1 0.0 1.9e-15 57.0 0.0 2.1 2 1 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KFL61586.1 - 6.2e-09 35.8 0.0 1.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 KFL61586.1 - 1.6e-08 34.8 0.1 8.6e-08 32.4 0.1 2.3 1 1 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KFL61586.1 - 6.6e-07 29.8 0.1 2.3e-06 28.1 0.0 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KFL61586.1 - 6.7e-07 29.2 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit MiaE PF06175.11 KFL61586.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) Cullin_Nedd8 PF10557.9 KFL61586.1 - 0.044 13.8 0.2 13 5.9 0.0 3.2 3 0 0 3 3 3 0 Cullin protein neddylation domain DEAD PF00270.29 KFL61586.1 - 0.045 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase TAFII28 PF04719.14 KFL61586.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Rep_fac_C PF08542.11 KFL61587.1 - 4.3e-16 59.1 0.0 1.9e-15 57.0 0.0 2.1 2 1 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KFL61587.1 - 6.2e-09 35.8 0.0 1.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 KFL61587.1 - 1.6e-08 34.8 0.1 8.6e-08 32.4 0.1 2.3 1 1 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KFL61587.1 - 6.6e-07 29.8 0.1 2.3e-06 28.1 0.0 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KFL61587.1 - 6.7e-07 29.2 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit MiaE PF06175.11 KFL61587.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) Cullin_Nedd8 PF10557.9 KFL61587.1 - 0.044 13.8 0.2 13 5.9 0.0 3.2 3 0 0 3 3 3 0 Cullin protein neddylation domain DEAD PF00270.29 KFL61587.1 - 0.045 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase TAFII28 PF04719.14 KFL61587.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region NmrA PF05368.13 KFL61588.1 - 1.9e-05 24.3 0.0 2.5e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family UCH PF00443.29 KFL61589.1 - 4.7e-08 32.8 0.0 8.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 KFL61589.1 - 0.018 14.4 0.0 0.61 9.3 0.0 2.3 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 DUF913 PF06025.12 KFL61589.1 - 0.97 8.3 6.0 1.4 7.8 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) eRF1_2 PF03464.15 KFL61591.1 - 1e-46 158.5 0.0 1.7e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFL61591.1 - 4.7e-39 133.4 0.2 1e-38 132.3 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KFL61591.1 - 1.8e-21 76.5 0.0 2.8e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KFL61591.1 - 4.4e-10 39.9 0.0 8.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KFL61591.1 - 8.9e-09 35.7 0.1 1.4e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor AA_kinase PF00696.28 KFL61592.1 - 9.9e-36 123.5 0.0 1.7e-35 122.8 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KFL61592.1 - 8.5e-14 51.1 1.2 1.3e-11 44.2 0.2 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KFL61592.1 - 5.2e-12 45.3 0.1 4.3e-09 36.0 0.1 3.0 3 0 0 3 3 3 2 ACT domain Peptidase_C78 PF07910.13 KFL61593.1 - 2.1e-32 112.3 0.1 3.1e-32 111.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 KFL61593.1 - 0.00042 20.6 3.5 0.038 14.3 1.0 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KFL61593.1 - 0.00067 19.2 0.1 0.0016 18.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 KFL61593.1 - 0.12 12.1 0.5 0.29 10.9 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFL61593.1 - 0.35 11.4 2.5 4.5 7.9 0.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFL61593.1 - 0.49 11.4 3.8 4 8.5 1.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_C78 PF07910.13 KFL61594.1 - 2.1e-32 112.3 0.1 3.1e-32 111.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 KFL61594.1 - 0.00042 20.6 3.5 0.038 14.3 1.0 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KFL61594.1 - 0.00067 19.2 0.1 0.0016 18.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 KFL61594.1 - 0.12 12.1 0.5 0.29 10.9 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFL61594.1 - 0.35 11.4 2.5 4.5 7.9 0.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFL61594.1 - 0.49 11.4 3.8 4 8.5 1.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger NAP PF00956.18 KFL61595.1 - 5.8e-99 330.6 7.7 5.8e-99 330.6 7.7 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) NAP PF00956.18 KFL61596.1 - 3.5e-99 331.4 7.7 3.5e-99 331.4 7.7 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF2457 PF10446.9 KFL61596.1 - 4.5 6.3 33.1 1 8.4 23.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 KFL61596.1 - 8 4.6 24.1 1.4 7.1 15.2 2.2 2 0 0 2 2 2 0 CDC45-like protein NAP PF00956.18 KFL61597.1 - 3.5e-99 331.4 7.7 3.5e-99 331.4 7.7 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF2457 PF10446.9 KFL61597.1 - 4.5 6.3 33.1 1 8.4 23.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 KFL61597.1 - 8 4.6 24.1 1.4 7.1 15.2 2.2 2 0 0 2 2 2 0 CDC45-like protein NAP PF00956.18 KFL61598.1 - 4.4e-69 232.7 4.3 5.8e-69 232.3 4.3 1.0 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF3306 PF11748.8 KFL61598.1 - 3.4 8.5 7.2 1.1 10.2 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) NAP PF00956.18 KFL61599.1 - 4.4e-69 232.7 4.3 5.8e-69 232.3 4.3 1.0 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF3306 PF11748.8 KFL61599.1 - 3.4 8.5 7.2 1.1 10.2 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) P5-ATPase PF12409.8 KFL61600.1 - 1.8e-40 137.9 0.0 3.7e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KFL61600.1 - 7.3e-31 107.1 0.0 1.4e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFL61600.1 - 1.5e-15 58.0 0.0 1.2e-06 28.9 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFL61600.1 - 0.00048 19.7 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFL61600.1 - 0.0005 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 KFL61600.1 - 0.033 13.9 6.3 0.081 12.6 0.3 2.7 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 KFL61600.1 - 0.036 13.8 0.0 9.6 5.9 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 KFL61601.1 - 1.8e-40 137.9 0.0 3.7e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KFL61601.1 - 7.3e-31 107.1 0.0 1.4e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFL61601.1 - 1.5e-15 58.0 0.0 1.2e-06 28.9 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFL61601.1 - 0.00048 19.7 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFL61601.1 - 0.0005 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 KFL61601.1 - 0.033 13.9 6.3 0.081 12.6 0.3 2.7 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 KFL61601.1 - 0.036 13.8 0.0 9.6 5.9 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 KFL61602.1 - 1.7e-40 138.0 0.0 3.6e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KFL61602.1 - 7.2e-31 107.1 0.0 1.3e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFL61602.1 - 1.4e-15 58.2 0.0 1.2e-06 29.0 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFL61602.1 - 0.00047 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFL61602.1 - 0.00047 20.2 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFL61602.1 - 0.034 13.9 0.0 9.3 5.9 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 KFL61603.1 - 1.7e-40 138.0 0.0 3.6e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KFL61603.1 - 7.2e-31 107.1 0.0 1.3e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFL61603.1 - 1.4e-15 58.2 0.0 1.2e-06 29.0 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFL61603.1 - 0.00047 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFL61603.1 - 0.00047 20.2 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFL61603.1 - 0.034 13.9 0.0 9.3 5.9 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 KFL61604.1 - 1.7e-40 138.0 0.0 3.6e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KFL61604.1 - 7.2e-31 107.1 0.0 1.3e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFL61604.1 - 1.4e-15 58.2 0.0 1.2e-06 29.0 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFL61604.1 - 0.00047 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFL61604.1 - 0.00047 20.2 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFL61604.1 - 0.034 13.9 0.0 9.3 5.9 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase G_glu_transpept PF01019.21 KFL61606.1 - 1.2e-50 172.8 0.1 1.4e-50 172.5 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Pkinase PF00069.25 KFL61607.1 - 1.5e-06 27.8 0.0 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61607.1 - 0.0073 15.6 0.0 0.008 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase tRNA-synt_2b PF00587.25 KFL61609.1 - 2.5e-34 118.8 0.0 4.3e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KFL61609.1 - 1e-19 70.8 4.4 1e-19 70.8 4.4 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain CAMSAP_CC1 PF17095.5 KFL61609.1 - 0.11 12.4 2.5 0.24 11.3 2.5 1.5 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin DUF4337 PF14235.6 KFL61609.1 - 2.1 8.4 4.3 3.7 7.6 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) tRNA-synt_2b PF00587.25 KFL61610.1 - 2.8e-34 118.7 0.0 3.7e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KFL61610.1 - 0.012 15.9 1.9 0.012 15.9 1.9 2.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3698 PF12479.8 KFL61610.1 - 0.046 14.3 0.1 0.19 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3698) CAMSAP_CC1 PF17095.5 KFL61610.1 - 0.29 11.0 3.5 0.49 10.3 3.5 1.4 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Ras PF00071.22 KFL61611.1 - 8.6e-43 145.7 0.1 9.7e-43 145.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL61611.1 - 3.2e-13 50.0 0.0 4.6e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL61611.1 - 9.5e-06 25.2 0.0 1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL61611.1 - 0.00012 21.7 0.1 0.00018 21.1 0.1 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFL61611.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase UPRTase PF14681.6 KFL61612.1 - 4.8e-69 231.9 0.0 6.1e-69 231.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFL61612.1 - 0.014 15.0 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain UPRTase PF14681.6 KFL61613.1 - 2.2e-65 220.0 0.0 2.6e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFL61613.1 - 0.0093 15.5 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Peptidase_S9 PF00326.21 KFL61615.1 - 0.00017 21.2 0.1 0.00032 20.2 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF5627 PF18620.1 KFL61615.1 - 0.023 14.6 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5627) ERAP1_C PF11838.8 KFL61617.1 - 3.4e-87 292.9 0.0 6.8e-87 291.9 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KFL61617.1 - 3.7e-84 281.7 5.1 6.7e-84 280.8 5.1 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Ras PF00071.22 KFL61617.1 - 5.9e-64 214.6 2.0 6.6e-64 214.4 0.6 1.8 2 0 0 2 2 2 1 Ras family Peptidase_M1_N PF17900.1 KFL61617.1 - 4.4e-39 134.6 0.1 1.7e-38 132.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Roc PF08477.13 KFL61617.1 - 1.6e-34 118.7 0.2 3.4e-34 117.6 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL61617.1 - 3.1e-15 56.1 0.3 6.6e-15 55.0 0.1 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFL61617.1 - 0.00097 19.2 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFL61617.1 - 0.0013 18.7 0.7 0.74 9.7 0.0 2.7 2 1 0 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 KFL61617.1 - 0.0032 16.9 0.1 0.0071 15.7 0.1 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFL61617.1 - 0.005 16.4 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFL61617.1 - 0.019 14.4 0.1 0.036 13.5 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.29 KFL61617.1 - 0.079 13.4 1.1 4.7 7.7 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFL61617.1 - 0.15 12.4 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.32 KFL61618.1 - 9.5e-32 108.5 17.6 5.1e-09 36.6 0.7 8.4 8 0 0 8 8 8 5 WD domain, G-beta repeat Utp12 PF04003.12 KFL61618.1 - 1.7e-27 95.9 0.0 2.6e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KFL61618.1 - 3.2e-15 56.2 0.0 0.0029 17.9 0.0 6.4 2 1 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFL61618.1 - 9.5e-11 41.2 0.4 0.15 11.0 0.0 4.9 3 2 2 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFL61618.1 - 2.4e-07 30.9 0.2 0.0061 16.5 0.0 3.7 4 1 0 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFL61618.1 - 9.9e-07 27.8 1.5 0.4 9.3 0.0 4.2 2 2 1 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.12 KFL61618.1 - 0.0096 15.8 0.1 20 5.3 0.0 4.7 5 0 0 5 5 4 0 WD40-like Beta Propeller Repeat Pox_T4_N PF04491.12 KFL61618.1 - 0.022 14.6 0.4 0.16 11.8 0.1 2.3 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus Hemagglutinin PF00509.18 KFL61618.1 - 0.079 11.3 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin WD40_like PF17005.5 KFL61618.1 - 0.081 12.2 0.0 1.9 7.7 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain PQQ_3 PF13570.6 KFL61618.1 - 0.26 11.9 3.9 39 4.9 0.0 4.4 5 0 0 5 5 4 0 PQQ-like domain HATPase_c PF02518.26 KFL61622.1 - 5.3e-07 30.1 0.0 3.3e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFL61622.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IF4E PF01652.18 KFL61623.1 - 8.1e-55 185.0 0.1 1.4e-54 184.2 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IF4E PF01652.18 KFL61624.1 - 9.3e-52 175.0 0.1 1.7e-51 174.2 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PLU-1 PF08429.11 KFL61625.1 - 4.2e-110 368.1 15.9 1.1e-107 360.1 14.5 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KFL61625.1 - 1.3e-42 144.8 1.0 4.4e-42 143.1 0.4 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 KFL61625.1 - 1.9e-12 47.4 5.2 6e-12 45.8 5.2 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.29 KFL61625.1 - 9.1e-10 38.3 18.6 1.2e-07 31.5 9.4 3.6 3 0 0 3 3 3 2 PHD-finger PHD_4 PF16866.5 KFL61625.1 - 0.24 11.5 11.0 0.16 12.1 4.6 2.9 2 0 0 2 2 2 0 PHD-finger PQ-loop PF04193.14 KFL61626.1 - 8.4e-20 70.3 5.4 2e-12 46.7 0.7 2.6 2 0 0 2 2 2 2 PQ loop repeat NMT1_3 PF16868.5 KFL61626.1 - 0.0082 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 KFL61626.1 - 0.0097 15.9 0.0 0.11 12.5 0.0 2.2 1 1 1 2 2 2 1 NMT1/THI5 like ER_lumen_recept PF00810.18 KFL61626.1 - 0.025 15.4 3.8 0.11 13.3 3.7 1.9 1 1 0 1 1 1 0 ER lumen protein retaining receptor SBP_bac_3 PF00497.20 KFL61626.1 - 0.18 11.2 0.0 1.1 8.7 0.0 1.9 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Ribosomal_L1 PF00687.21 KFL61627.1 - 1.4e-31 109.9 0.0 2.3e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF1961 PF09224.11 KFL61628.1 - 0.19 11.1 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) IPP-2 PF04979.14 KFL61629.1 - 2.1e-19 70.6 14.3 2.1e-19 70.6 14.3 2.6 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) FAM217 PF15344.6 KFL61629.1 - 2.7 7.9 13.0 0.13 12.2 6.4 2.0 1 1 2 3 3 3 0 FAM217 family IPP-2 PF04979.14 KFL61630.1 - 4.6e-20 72.7 18.2 4.6e-20 72.7 18.2 2.5 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) ELFV_dehydrog PF00208.21 KFL61632.1 - 3.2e-80 269.4 0.8 4e-80 269.1 0.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFL61632.1 - 3.8e-28 97.9 0.0 8.6e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 KFL61633.1 - 3.1e-80 269.4 0.8 3.9e-80 269.1 0.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFL61633.1 - 3.7e-28 98.0 0.0 8.5e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 KFL61634.1 - 1.8e-80 270.2 0.8 2.2e-80 269.9 0.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFL61634.1 - 7.5e-20 71.1 0.1 1.8e-19 69.9 0.1 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 KFL61635.1 - 1.8e-80 270.2 0.8 2.2e-80 269.9 0.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFL61635.1 - 7.5e-20 71.1 0.1 1.8e-19 69.9 0.1 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 KFL61636.1 - 1.8e-80 270.2 0.8 2.2e-80 269.9 0.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFL61636.1 - 7.5e-20 71.1 0.1 1.8e-19 69.9 0.1 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain MFS_1 PF07690.16 KFL61637.1 - 5.9e-11 41.9 17.5 2e-10 40.2 16.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL61637.1 - 0.00018 20.5 11.7 0.0003 19.8 11.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4271 PF14093.6 KFL61637.1 - 0.59 10.0 11.0 0.068 13.1 5.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Ribonuc_red_lgC PF02867.15 KFL61638.1 - 1.6e-186 620.9 0.0 2.1e-186 620.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KFL61638.1 - 8.2e-26 89.8 0.0 1.8e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KFL61638.1 - 5.9e-13 49.2 0.1 2.2e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain Ribonuc_red_lgC PF02867.15 KFL61639.1 - 1.4e-186 621.1 0.0 1.7e-186 620.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KFL61639.1 - 7.7e-26 89.9 0.0 1.6e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain Ribonuc_red_lgC PF02867.15 KFL61640.1 - 1.4e-186 621.1 0.0 1.7e-186 620.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KFL61640.1 - 7.8e-26 89.9 0.0 1.6e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain MID_MedPIWI PF18296.1 KFL61641.1 - 0.45 10.3 3.7 0.57 9.9 3.7 1.1 1 0 0 1 1 1 0 MID domain of medPIWI SPX PF03105.19 KFL61641.1 - 7.9 6.3 8.3 9 6.1 8.3 1.0 1 0 0 1 1 1 0 SPX domain Pkinase PF00069.25 KFL61642.1 - 9.5e-05 21.9 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Atrophin-1 PF03154.15 KFL61642.1 - 0.0038 15.6 6.5 0.0059 15.0 6.5 1.3 1 0 0 1 1 1 1 Atrophin-1 family Pkinase_Tyr PF07714.17 KFL61642.1 - 0.08 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase CDC45 PF02724.14 KFL61642.1 - 2.2 6.5 5.4 2.7 6.2 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC_4 PF14392.6 KFL61642.1 - 2.8 7.7 5.1 2 8.2 0.2 2.7 3 0 0 3 3 3 0 Zinc knuckle PRP38_assoc PF12871.7 KFL61642.1 - 4 8.1 30.7 0.58 10.8 25.6 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 PF13054.6 KFL61642.1 - 4.1 7.4 11.3 1.5 8.8 8.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) HEAT_2 PF13646.6 KFL61643.1 - 0.062 13.7 0.1 12 6.4 0.0 3.8 3 0 0 3 3 3 0 HEAT repeats GerD PF17898.1 KFL61643.1 - 0.078 12.9 1.0 0.19 11.7 1.0 1.7 1 0 0 1 1 1 0 Spore germination GerD central core domain Exo70 PF03081.15 KFL61643.1 - 0.31 10.0 3.9 1.5 7.7 0.6 2.6 3 0 0 3 3 3 0 Exo70 exocyst complex subunit Asn_synthase PF00733.21 KFL61644.1 - 7.9e-89 298.8 0.1 1.5e-52 179.4 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KFL61644.1 - 4.3e-36 123.5 0.0 7.2e-36 122.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFL61644.1 - 4.6e-26 91.6 0.0 7.7e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFL61644.1 - 1e-06 28.4 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KFL61644.1 - 0.00094 18.4 0.1 0.0049 16.0 0.1 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KFL61645.1 - 3.8e-85 286.7 0.1 1.4e-52 179.5 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KFL61645.1 - 4.2e-36 123.6 0.0 7e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFL61645.1 - 4.4e-26 91.7 0.0 7.5e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFL61645.1 - 1e-06 28.4 0.0 1.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KFL61645.1 - 0.00089 18.4 0.1 0.0049 16.0 0.1 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KFL61646.1 - 3.8e-85 286.7 0.1 1.4e-52 179.5 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KFL61646.1 - 4.2e-36 123.6 0.0 7e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFL61646.1 - 4.4e-26 91.7 0.0 7.5e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFL61646.1 - 1e-06 28.4 0.0 1.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KFL61646.1 - 0.00089 18.4 0.1 0.0049 16.0 0.1 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KFL61647.1 - 6.9e-89 299.0 0.1 1.4e-52 179.6 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KFL61647.1 - 4e-36 123.6 0.0 6.7e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFL61647.1 - 4.4e-26 91.7 0.0 7.2e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFL61647.1 - 9.8e-07 28.4 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KFL61647.1 - 0.00085 18.5 0.1 0.0047 16.1 0.1 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KFL61648.1 - 6e-89 299.2 0.1 1.3e-52 179.7 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KFL61648.1 - 8.8e-34 116.1 0.0 1.6e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFL61648.1 - 2.1e-20 73.3 0.0 3.8e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFL61648.1 - 9.8e-07 28.4 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KFL61648.1 - 0.00078 18.6 0.1 0.0044 16.2 0.1 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KFL61649.1 - 6e-89 299.2 0.1 1.3e-52 179.7 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KFL61649.1 - 8.8e-34 116.1 0.0 1.6e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFL61649.1 - 2.1e-20 73.3 0.0 3.8e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFL61649.1 - 9.8e-07 28.4 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KFL61649.1 - 0.00078 18.6 0.1 0.0044 16.2 0.1 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KFL61650.1 - 3.6e-89 299.9 0.1 9.7e-53 180.1 0.0 2.0 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KFL61650.1 - 4.6e-13 49.2 0.0 8.2e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFL61650.1 - 8.4e-07 28.7 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.6 KFL61650.1 - 0.00016 21.9 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 KFL61650.1 - 0.00056 19.1 0.1 0.0032 16.6 0.1 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KFL61651.1 - 3.6e-89 299.9 0.1 9.7e-53 180.1 0.0 2.0 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KFL61651.1 - 4.6e-13 49.2 0.0 8.2e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFL61651.1 - 8.4e-07 28.7 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.6 KFL61651.1 - 0.00016 21.9 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 KFL61651.1 - 0.00056 19.1 0.1 0.0032 16.6 0.1 2.0 1 1 0 1 1 1 1 NAD synthase Fungal_trans PF04082.18 KFL61653.1 - 7.1e-15 54.8 0.7 6.1e-14 51.7 0.2 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Fungal_trans PF04082.18 KFL61654.1 - 1.1e-09 37.7 0.2 1.9e-08 33.7 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain CK_II_beta PF01214.18 KFL61655.1 - 5.3e-75 251.2 0.0 1e-74 250.3 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.8 KFL61655.1 - 0.032 15.2 5.6 0.032 15.2 5.6 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.11 KFL61655.1 - 0.074 11.6 1.3 0.11 11.0 1.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PTPRCAP PF15713.5 KFL61655.1 - 3.3 8.0 7.8 21 5.4 5.2 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Aminotran_4 PF01063.19 KFL61656.1 - 2.5e-36 125.6 0.0 3.2e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Aminotran_4 PF01063.19 KFL61657.1 - 1.5e-36 126.4 0.0 1.8e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Aminotran_4 PF01063.19 KFL61658.1 - 1.4e-36 126.4 0.0 1.7e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DUF2721 PF11026.8 KFL61659.1 - 0.001 18.9 0.2 0.001 18.9 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) DUF2534 PF10749.9 KFL61659.1 - 0.0089 16.2 0.2 0.015 15.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2534) DUF4236 PF14020.6 KFL61659.1 - 0.019 15.5 0.1 0.039 14.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) WD40 PF00400.32 KFL61660.1 - 8.6e-22 77.0 27.5 5.9e-06 26.9 0.2 7.1 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL61660.1 - 1.4e-11 44.5 8.5 0.00015 22.0 0.2 4.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KFL61660.1 - 0.0015 18.5 11.8 0.27 11.1 5.0 2.8 1 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term WD40 PF00400.32 KFL61661.1 - 1.1e-21 76.7 27.9 5.9e-06 26.9 0.2 7.2 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL61661.1 - 1.9e-11 44.1 8.2 0.00014 22.0 0.2 4.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KFL61661.1 - 0.0027 17.6 11.9 0.14 12.1 2.7 2.8 2 2 1 3 3 3 2 Transcription factor IIIC subunit delta N-term WD40 PF00400.32 KFL61662.1 - 4.9e-22 77.8 27.5 5.3e-06 27.1 0.2 7.1 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL61662.1 - 1.1e-11 44.8 8.2 0.00013 22.2 0.2 4.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KFL61662.1 - 0.0012 18.8 11.9 0.041 13.8 1.9 2.8 1 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term WD40 PF00400.32 KFL61663.1 - 1.2e-11 45.0 18.6 4.9e-05 24.0 0.7 5.4 4 2 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL61663.1 - 5.5e-07 29.8 3.1 0.018 15.3 0.4 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KFL61663.1 - 0.00033 20.6 8.6 0.038 13.9 1.8 2.8 2 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term WD40 PF00400.32 KFL61664.1 - 1.2e-11 45.0 18.6 4.9e-05 24.0 0.7 5.4 4 2 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL61664.1 - 5.5e-07 29.8 3.1 0.018 15.3 0.4 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KFL61664.1 - 0.00033 20.6 8.6 0.038 13.9 1.8 2.8 2 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term WD40 PF00400.32 KFL61665.1 - 1.2e-11 45.0 18.6 4.9e-05 24.0 0.7 5.4 4 2 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL61665.1 - 5.5e-07 29.8 3.1 0.018 15.3 0.4 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KFL61665.1 - 0.00033 20.6 8.6 0.038 13.9 1.8 2.8 2 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term Ank_4 PF13637.6 KFL61666.1 - 5.9e-19 68.2 3.9 3.1e-09 37.2 0.0 4.5 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFL61666.1 - 7.9e-19 68.0 0.5 7.1e-10 39.3 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) GDPD PF03009.17 KFL61666.1 - 2.6e-13 50.3 0.0 5.2e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_5 PF13857.6 KFL61666.1 - 1e-09 38.5 0.6 0.076 13.4 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFL61666.1 - 1.1e-09 37.7 4.3 0.066 13.8 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KFL61666.1 - 3e-06 27.4 3.2 4.3 8.0 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 KFL61667.1 - 1e-20 74.1 4.8 5.8e-10 39.6 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFL61667.1 - 3.7e-19 68.8 4.0 2.7e-09 37.4 0.0 4.5 1 1 2 4 4 4 3 Ankyrin repeats (many copies) GDPD PF03009.17 KFL61667.1 - 1.7e-11 44.4 0.0 3.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_5 PF13857.6 KFL61667.1 - 6e-10 39.2 0.7 0.066 13.6 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFL61667.1 - 7.4e-10 38.2 4.7 0.057 14.0 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KFL61667.1 - 1.6e-06 28.3 3.2 3.7 8.2 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat SKG6 PF08693.10 KFL61668.1 - 5.6e-09 35.3 4.5 1.1e-08 34.3 4.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KFL61668.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) ASFV_J13L PF05568.11 KFL61668.1 - 0.015 15.1 1.3 0.049 13.4 1.1 2.0 1 1 0 1 1 1 0 African swine fever virus J13L protein DUF2207 PF09972.9 KFL61668.1 - 0.27 9.9 0.0 0.43 9.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Adeno_E3_CR2 PF02439.15 KFL61668.1 - 0.31 10.8 1.1 0.53 10.1 1.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Phage_holin_2_4 PF16082.5 KFL61668.1 - 0.32 10.8 0.0 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like TMEM154 PF15102.6 KFL61668.1 - 0.5 10.3 1.9 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family FAD-SLDH PF12318.8 KFL61669.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase RRM_1 PF00076.22 KFL61672.1 - 2.1e-12 46.7 0.0 2.9e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFL61672.1 - 0.00033 20.6 0.0 0.00046 20.1 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Oxidored_q6 PF01058.22 KFL61673.1 - 7.1e-18 64.7 0.0 1.3e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Oxidored_q6 PF01058.22 KFL61674.1 - 3e-22 78.9 0.0 4.7e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Oxidored_q6 PF01058.22 KFL61675.1 - 3e-22 78.9 0.0 4.7e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit UDG PF03167.19 KFL61676.1 - 2.6e-20 73.0 0.2 4.4e-20 72.2 0.1 1.4 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily UCH PF00443.29 KFL61677.1 - 6.1e-36 124.2 0.0 8.3e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFL61677.1 - 1.1e-19 70.5 1.4 1.1e-19 70.5 1.4 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFL61677.1 - 2.2e-15 57.1 0.0 5.3e-13 49.3 0.0 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KFL61677.1 - 1.4e-14 53.7 0.2 3.8e-07 29.9 0.0 2.7 3 0 0 3 3 3 2 UBA/TS-N domain UBA_4 PF14555.6 KFL61677.1 - 0.0083 15.9 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain DUF3795 PF12675.7 KFL61677.1 - 5.1 7.6 12.4 9.6 6.7 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3795) UCH PF00443.29 KFL61678.1 - 2.1e-25 89.7 0.0 2.9e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFL61678.1 - 9.7e-20 70.7 1.4 9.7e-20 70.7 1.4 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 KFL61678.1 - 1.1e-14 53.9 0.2 3.5e-07 30.0 0.0 2.7 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.6 KFL61678.1 - 1.5e-05 24.8 0.0 0.0028 17.3 0.0 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KFL61678.1 - 0.0074 16.1 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain DUF3795 PF12675.7 KFL61678.1 - 4.3 7.8 12.5 8.7 6.8 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3795) UCH PF00443.29 KFL61679.1 - 2.1e-36 125.8 0.0 2.6e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFL61679.1 - 9.2e-16 58.3 0.0 1.9e-13 50.7 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KFL61679.1 - 5.5e-15 54.9 0.2 2.5e-07 30.5 0.0 2.7 3 0 0 3 3 3 2 UBA/TS-N domain UBA_4 PF14555.6 KFL61679.1 - 0.0054 16.5 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain ThiF PF00899.21 KFL61680.1 - 4.5e-43 147.4 0.0 5.8e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family ApbA PF02558.16 KFL61680.1 - 0.0018 17.9 0.0 0.035 13.8 0.1 2.7 2 1 1 3 3 3 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KFL61680.1 - 0.0077 16.3 0.1 0.026 14.6 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KFL61680.1 - 0.027 13.8 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KFL61680.1 - 0.16 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.21 KFL61681.1 - 9.2e-32 110.3 0.0 1.2e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family ATPase-cat_bd PF12156.8 KFL61681.1 - 0.044 14.5 2.0 19 6.0 0.0 3.2 3 0 0 3 3 3 0 Putative metal-binding domain of cation transport ATPase dCMP_cyt_deam_1 PF00383.23 KFL61682.1 - 2.3e-13 49.9 0.0 4.4e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFL61682.1 - 3.5e-06 26.8 0.0 9.8e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 MafB19-like deaminase AAA_18 PF13238.6 KFL61682.1 - 0.011 16.3 0.1 0.076 13.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain CoaE PF01121.20 KFL61682.1 - 0.048 13.3 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase dCMP_cyt_deam_1 PF00383.23 KFL61683.1 - 2.5e-12 46.5 0.9 3.6e-12 46.1 0.9 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFL61683.1 - 0.00077 19.2 0.3 0.00089 19.0 0.3 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KFL61683.1 - 0.14 12.3 0.6 0.18 11.9 0.6 1.4 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Thioredoxin PF00085.20 KFL61684.1 - 3.8e-51 171.4 9.3 8.4e-32 109.2 0.1 4.2 4 0 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.6 KFL61684.1 - 4e-49 167.0 2.5 1.7e-38 132.4 1.4 2.4 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFL61684.1 - 4.4e-07 30.0 0.2 0.032 14.4 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.17 KFL61684.1 - 1.5e-06 27.6 7.2 2.9e-05 23.3 7.1 2.2 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.6 KFL61684.1 - 3.6e-06 27.4 4.6 0.00051 20.5 0.1 3.7 2 1 1 3 3 3 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KFL61684.1 - 6.9e-06 26.0 0.8 0.00075 19.4 0.1 3.0 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KFL61684.1 - 1.1e-05 25.6 1.0 0.15 12.4 0.0 4.8 4 1 1 5 5 5 1 Thioredoxin-like OST3_OST6 PF04756.13 KFL61684.1 - 0.0017 17.8 1.2 0.035 13.4 0.0 2.9 2 1 1 3 3 3 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KFL61684.1 - 0.0044 16.7 0.8 0.43 10.3 0.1 2.9 3 0 0 3 3 3 1 Redoxin Thioredoxin_3 PF13192.6 KFL61684.1 - 0.014 15.5 0.1 0.062 13.3 0.1 2.1 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_6 PF13848.6 KFL61685.1 - 1.3e-44 152.4 5.1 1.3e-38 132.7 1.1 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.20 KFL61685.1 - 7.4e-36 122.3 3.7 3.4e-27 94.4 0.0 3.3 3 0 0 3 3 3 3 Thioredoxin OST3_OST6 PF04756.13 KFL61685.1 - 1.3e-05 24.7 0.8 0.00035 20.0 0.0 2.7 1 1 1 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KFL61685.1 - 0.0006 20.1 0.2 0.054 13.8 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KFL61685.1 - 0.0016 18.6 0.0 0.0079 16.4 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFL61685.1 - 0.0046 17.4 0.9 0.15 12.6 0.3 3.2 2 1 0 2 2 2 1 Thioredoxin-like domain zf-RING_2 PF13639.6 KFL61686.1 - 0.012 15.9 5.3 0.021 15.1 5.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KFL61686.1 - 0.028 14.3 8.9 0.051 13.4 8.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PDZ_assoc PF10600.9 KFL61686.1 - 0.06 14.2 1.2 0.06 14.2 1.2 2.7 2 1 1 3 3 3 0 PDZ-associated domain of NMDA receptors DUF1272 PF06906.11 KFL61686.1 - 0.099 12.7 4.7 0.18 11.9 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 KFL61686.1 - 0.18 11.6 5.8 0.37 10.6 5.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFL61686.1 - 0.33 11.2 6.1 0.78 10.0 6.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Macoilin PF09726.9 KFL61686.1 - 0.52 8.8 8.8 0.97 7.9 8.8 1.4 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 KFL61686.1 - 0.57 8.8 7.7 0.75 8.4 7.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dicty_REP PF05086.12 KFL61686.1 - 0.76 7.7 7.9 1 7.2 7.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C3HC4 PF00097.25 KFL61686.1 - 0.96 9.4 7.6 1.8 8.5 7.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FRG2 PF15315.6 KFL61686.1 - 1.1 9.4 17.8 3.8 7.7 17.8 1.8 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 FYVE_2 PF02318.16 KFL61686.1 - 1.2 9.3 6.0 0.3 11.3 2.5 1.7 1 1 1 2 2 2 0 FYVE-type zinc finger CDC45 PF02724.14 KFL61686.1 - 2.2 6.5 11.7 3.4 5.9 11.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoporin_N PF08801.11 KFL61687.1 - 4.8e-50 170.6 0.0 6.8e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KFL61687.1 - 4.2e-13 48.9 2.8 5.6e-13 48.5 2.8 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_C PF03177.14 KFL61688.1 - 2e-100 337.3 0.2 2.2e-100 337.1 0.2 1.0 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Serpin PF00079.20 KFL61688.1 - 0.18 11.1 0.3 0.25 10.6 0.3 1.1 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) WD40 PF00400.32 KFL61689.1 - 6e-24 83.9 12.4 1.9e-08 34.8 0.3 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL61689.1 - 3.1e-15 56.2 0.4 0.00014 22.1 0.4 4.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFL61689.1 - 0.00014 21.8 0.0 0.022 14.7 0.0 2.8 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFL61689.1 - 0.00043 19.0 0.1 0.64 8.6 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KFL61689.1 - 0.0011 18.3 0.3 2.5 7.4 0.0 3.4 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 KFL61689.1 - 0.0013 17.3 0.0 0.0039 15.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain PQQ_3 PF13570.6 KFL61689.1 - 0.035 14.6 0.6 2 9.0 0.0 3.5 3 1 0 3 3 3 0 PQQ-like domain Hira PF07569.11 KFL61689.1 - 0.044 13.5 0.0 9.7 5.8 0.0 3.0 2 1 1 3 3 3 0 TUP1-like enhancer of split Nucleoporin_N PF08801.11 KFL61689.1 - 0.051 12.3 0.0 0.52 9.0 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like Ge1_WD40 PF16529.5 KFL61689.1 - 0.11 11.5 0.4 18 4.2 0.0 3.2 1 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L32p PF01783.23 KFL61690.1 - 4.6e-14 52.4 7.1 6.6e-14 51.9 7.1 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family DZR PF12773.7 KFL61690.1 - 0.0081 16.2 0.8 0.013 15.5 0.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KFL61690.1 - 0.028 14.3 0.8 0.052 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.12 KFL61690.1 - 0.031 14.3 0.7 0.044 13.8 0.7 1.2 1 0 0 1 1 1 0 zinc-ribbons zf-ribbon_3 PF13248.6 KFL61690.1 - 0.19 11.2 5.6 0.65 9.5 5.8 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 KFL61690.1 - 0.2 11.7 3.0 0.37 10.9 3.0 1.5 1 1 0 1 1 1 0 Transposase zinc-binding domain Zn-ribbon_8 PF09723.10 KFL61690.1 - 0.21 11.7 4.5 5.9 7.1 0.4 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KFL61690.1 - 3.3 7.7 6.4 1.6e+02 2.4 6.4 2.3 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-XS PF03470.14 KFL61690.1 - 4.7 7.6 8.7 19 5.6 0.2 3.3 3 0 0 3 3 3 0 XS zinc finger domain DAO_C PF16901.5 KFL61691.1 - 3.9e-36 123.7 0.0 6.3e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase DAO PF01266.24 KFL61691.1 - 5.9e-31 108.3 0.0 7.9e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KFL61692.1 - 5.5e-16 59.1 0.5 1e-15 58.2 0.3 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFL61692.1 - 1.2e-05 24.8 0.7 1.5e-05 24.5 0.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFL61692.1 - 4.4e-05 22.7 0.9 7.1e-05 22.1 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFL61692.1 - 0.00016 21.0 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KFL61692.1 - 0.0011 18.9 0.1 0.0016 18.4 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KFL61692.1 - 0.0014 18.8 0.2 0.0029 17.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KFL61692.1 - 0.0019 17.4 0.1 0.0027 16.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KFL61692.1 - 0.0031 16.3 0.3 0.0048 15.7 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Methyltransf_34 PF11312.8 KFL61692.1 - 0.0067 15.7 0.1 0.0084 15.4 0.1 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Pyr_redox PF00070.27 KFL61692.1 - 0.027 15.0 0.2 0.027 15.0 0.2 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFL61692.1 - 0.046 13.0 0.2 0.063 12.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KFL61692.1 - 0.049 12.9 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFL61692.1 - 0.093 11.8 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KFL61692.1 - 0.16 11.2 0.3 0.23 10.7 0.3 1.2 1 0 0 1 1 1 0 Thi4 family p450 PF00067.22 KFL61693.1 - 1.8e-65 221.5 0.0 2.1e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFL61694.1 - 3.4e-40 138.2 0.0 7.2e-34 117.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KFL61695.1 - 8.1e-44 150.1 0.0 1e-43 149.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFL61696.1 - 6.4e-45 153.7 0.8 3.4e-26 92.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF2293 PF10056.9 KFL61697.1 - 1.8e-05 24.9 0.2 0.00013 22.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Ca_chan_IQ PF08763.11 KFL61697.1 - 0.059 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Spy1 PF11357.8 KFL61700.1 - 0.068 13.5 0.0 0.069 13.5 0.0 1.1 1 0 0 1 1 1 0 Cell cycle regulatory protein RRM_1 PF00076.22 KFL61701.1 - 3.9e-23 81.0 0.0 5.1e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFL61701.1 - 0.00035 20.6 0.0 0.00066 19.7 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 KFL61701.1 - 0.052 13.6 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif RRM_1 PF00076.22 KFL61702.1 - 3.8e-23 81.1 0.0 5e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFL61702.1 - 0.00038 20.5 0.0 0.00064 19.8 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 KFL61702.1 - 0.054 13.5 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif G6PD_C PF02781.16 KFL61703.1 - 1.6e-110 368.8 0.0 2.5e-110 368.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KFL61703.1 - 3.4e-61 207.0 0.0 8.1e-61 205.7 0.0 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.16 KFL61704.1 - 1.2e-114 382.4 0.0 1.8e-114 381.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KFL61704.1 - 1.7e-40 139.5 0.1 4.1e-40 138.3 0.1 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.16 KFL61705.1 - 1.2e-114 382.4 0.0 1.8e-114 381.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KFL61705.1 - 1.7e-40 139.5 0.1 4.1e-40 138.3 0.1 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.16 KFL61706.1 - 1.1e-110 369.4 0.0 1.7e-110 368.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KFL61706.1 - 1.4e-40 139.8 0.1 3.7e-40 138.4 0.1 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.16 KFL61707.1 - 1.1e-110 369.4 0.0 1.7e-110 368.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KFL61707.1 - 1.4e-40 139.8 0.1 3.7e-40 138.4 0.1 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.16 KFL61709.1 - 1.2e-05 24.4 22.1 7.1e-05 21.9 21.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFL61709.1 - 0.00046 18.7 2.9 0.00046 18.7 2.9 1.8 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFL61710.1 - 2.4e-29 102.4 3.1 3.1e-29 102.0 3.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL61710.1 - 4.9e-08 32.3 6.2 8.9e-08 31.4 6.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFL61710.1 - 0.00012 21.1 0.5 0.00025 20.0 0.4 1.9 1 1 0 1 1 1 1 MFS_1 like family TRI12 PF06609.13 KFL61710.1 - 0.0028 16.1 0.6 0.0038 15.7 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KFL61710.1 - 0.0035 16.7 2.2 0.0064 15.8 2.2 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 KFL61710.1 - 0.0085 14.7 2.3 0.015 13.9 2.3 1.5 1 0 0 1 1 1 1 MFS/sugar transport protein ATG22 PF11700.8 KFL61710.1 - 0.0093 14.6 3.8 0.061 11.9 1.3 2.8 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like MFS_3 PF05977.13 KFL61710.1 - 0.011 14.1 0.9 0.016 13.6 0.9 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector ExoD PF06055.12 KFL61710.1 - 0.037 13.4 3.2 0.078 12.4 3.2 1.5 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Pkinase PF00069.25 KFL61713.1 - 2.1e-68 230.6 0.0 3.1e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61713.1 - 1.8e-34 119.2 0.0 4.1e-34 118.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFL61713.1 - 1e-05 25.0 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFL61713.1 - 0.0031 16.9 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TetR_C_27 PF17935.1 KFL61713.1 - 0.06 13.4 0.0 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain YrbL-PhoP_reg PF10707.9 KFL61713.1 - 0.13 11.7 2.1 0.28 10.7 0.0 2.5 4 0 0 4 4 4 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 KFL61714.1 - 2.9e-54 184.2 0.1 1e-31 110.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61714.1 - 6.6e-22 78.0 0.2 5.1e-21 75.1 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KFL61715.1 - 2.5e-60 204.1 0.0 3.8e-60 203.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61715.1 - 2.5e-27 95.8 0.2 5.5e-27 94.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFL61715.1 - 7.7e-06 25.4 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFL61715.1 - 0.0024 17.2 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TetR_C_27 PF17935.1 KFL61715.1 - 0.045 13.8 0.0 0.42 10.7 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain YrbL-PhoP_reg PF10707.9 KFL61715.1 - 0.077 12.5 1.7 0.22 11.0 0.0 2.5 4 0 0 4 4 4 0 PhoP regulatory network protein YrbL GCP_N_terminal PF17681.1 KFL61716.1 - 5.2e-61 206.9 0.0 9e-61 206.1 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFL61716.1 - 3e-59 201.0 3.6 3e-59 201.0 3.6 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal DUF3346 PF11826.8 KFL61716.1 - 0.094 12.5 0.3 0.16 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) GCP_N_terminal PF17681.1 KFL61717.1 - 4.5e-61 207.1 0.0 6.9e-61 206.5 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFL61717.1 - 8.8e-52 176.5 1.5 8.8e-52 176.5 1.5 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal DUF3346 PF11826.8 KFL61717.1 - 0.089 12.6 0.3 0.15 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) Fungal_trans_2 PF11951.8 KFL61718.1 - 7.2e-15 54.7 1.0 1.1e-14 54.1 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KFL61719.1 - 7.2e-15 54.7 1.0 1.1e-14 54.1 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PUMA PF15826.5 KFL61720.1 - 0.12 12.6 2.0 0.25 11.5 0.9 1.8 1 1 1 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis DNA_pol_phi PF04931.13 KFL61721.1 - 0.033 12.3 1.8 0.034 12.3 1.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 KFL61721.1 - 0.049 13.4 0.3 0.068 13.0 0.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2457 PF10446.9 KFL61721.1 - 0.15 11.2 5.4 0.18 10.9 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 KFL61721.1 - 0.35 10.2 2.4 0.38 10.1 2.4 1.1 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 KFL61721.1 - 0.36 11.2 8.6 0.63 10.5 8.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PGA2 PF07543.12 KFL61721.1 - 0.89 9.5 2.6 1.4 8.9 2.6 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 DNA_pol_phi PF04931.13 KFL61722.1 - 0.033 12.3 1.8 0.034 12.3 1.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 KFL61722.1 - 0.049 13.4 0.3 0.068 13.0 0.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2457 PF10446.9 KFL61722.1 - 0.15 11.2 5.4 0.18 10.9 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 KFL61722.1 - 0.35 10.2 2.4 0.38 10.1 2.4 1.1 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 KFL61722.1 - 0.36 11.2 8.6 0.63 10.5 8.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PGA2 PF07543.12 KFL61722.1 - 0.89 9.5 2.6 1.4 8.9 2.6 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 MTHFR PF02219.17 KFL61723.1 - 1.1e-115 386.0 0.0 1.5e-115 385.4 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1804 PF08822.11 KFL61723.1 - 0.062 13.3 0.1 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) Pkinase PF00069.25 KFL61725.1 - 5e-70 235.9 0.0 6.1e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61725.1 - 2.3e-33 115.6 0.0 3.1e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFL61725.1 - 2.4e-06 26.8 0.0 3.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFL61725.1 - 0.0043 16.4 0.0 0.0075 15.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.30 KFL61725.1 - 0.02 15.2 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 C2 domain APH PF01636.23 KFL61725.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Coatomer_WDAD PF04053.14 KFL61726.1 - 7.5e-84 282.3 0.3 9e-84 282.1 0.3 1.0 1 0 0 1 1 1 1 Coatomer WD associated region Coatomer_WDAD PF04053.14 KFL61727.1 - 4.7e-59 200.6 0.0 1.5e-58 199.0 0.0 1.8 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KFL61727.1 - 2e-39 132.9 6.7 1.5e-06 28.8 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL61727.1 - 2.2e-07 31.0 0.0 1.8 8.9 0.0 5.9 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFL61727.1 - 0.00015 20.6 3.3 0.084 11.5 0.1 4.0 1 1 3 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KFL61727.1 - 0.012 15.6 0.0 6.5 6.8 0.0 3.8 2 2 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 KFL61727.1 - 0.075 13.3 0.1 0.46 10.7 0.0 2.1 1 1 0 2 2 2 0 C terminal of Calcineurin-like phosphoesterase ETC_C1_NDUFA5 PF04716.14 KFL61728.1 - 1.5e-27 95.2 1.4 3.9e-25 87.5 0.1 2.5 2 0 0 2 2 2 2 ETC complex I subunit conserved region ETC_C1_NDUFA5 PF04716.14 KFL61729.1 - 1.6e-25 88.6 0.1 3.2e-25 87.7 0.1 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region Thioredoxin PF00085.20 KFL61730.1 - 1.4e-40 137.5 0.0 3.5e-24 84.8 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KFL61730.1 - 1.8e-10 41.0 0.0 8.8e-05 22.5 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFL61730.1 - 0.00078 19.7 0.0 0.58 10.5 0.0 3.8 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.11 KFL61730.1 - 0.0014 18.6 0.0 0.64 10.0 0.0 2.7 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 KFL61730.1 - 0.0018 18.7 1.2 1.2 9.6 0.1 3.7 3 1 0 3 3 3 1 Thioredoxin-like domain TraF PF13728.6 KFL61730.1 - 0.026 14.3 6.9 0.39 10.5 0.0 3.7 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KFL61730.1 - 0.053 13.6 0.8 0.55 10.3 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin domain Thioredoxin_7 PF13899.6 KFL61730.1 - 0.06 13.5 1.6 0.29 11.3 0.1 2.8 3 0 0 3 3 3 0 Thioredoxin-like Thioredoxin PF00085.20 KFL61731.1 - 1e-40 137.9 0.1 3e-24 85.0 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KFL61731.1 - 3.5e-10 40.1 0.0 7.6e-05 22.7 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFL61731.1 - 0.00088 19.6 0.0 0.51 10.7 0.0 3.8 3 1 0 3 3 3 1 Thioredoxin-like HyaE PF07449.11 KFL61731.1 - 0.0012 18.8 0.0 0.56 10.2 0.0 2.7 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 KFL61731.1 - 0.0029 18.0 0.9 1 9.8 0.1 3.6 3 2 0 3 3 3 1 Thioredoxin-like domain TraF PF13728.6 KFL61731.1 - 0.025 14.4 8.0 0.34 10.7 0.0 3.8 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KFL61731.1 - 0.044 14.0 1.6 0.26 11.5 0.1 2.9 3 0 0 3 3 3 0 Thioredoxin-like Thioredoxin_3 PF13192.6 KFL61731.1 - 0.065 13.3 0.9 0.48 10.5 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin domain Thioredoxin PF00085.20 KFL61732.1 - 7.1e-41 138.4 0.0 2.9e-24 85.0 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KFL61732.1 - 2.7e-10 40.5 0.0 7.5e-05 22.7 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFL61732.1 - 0.00046 20.5 0.0 0.49 10.8 0.0 3.8 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFL61732.1 - 0.001 19.5 1.2 0.99 9.9 0.1 3.8 3 1 0 3 3 3 1 Thioredoxin-like domain HyaE PF07449.11 KFL61732.1 - 0.0011 18.9 0.0 0.54 10.2 0.0 2.7 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KFL61732.1 - 0.019 14.8 7.2 0.33 10.7 0.0 3.8 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KFL61732.1 - 0.036 14.1 0.8 0.47 10.6 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin domain Thioredoxin_7 PF13899.6 KFL61732.1 - 0.042 14.0 1.6 0.25 11.6 0.1 2.9 3 0 0 3 3 3 0 Thioredoxin-like OST3_OST6 PF04756.13 KFL61732.1 - 0.053 12.9 0.3 7 5.9 0.1 2.5 2 1 0 2 2 2 0 OST3 / OST6 family, transporter family HNH_2 PF13391.6 KFL61734.1 - 0.00022 21.3 0.0 0.00054 20.0 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease BNIP3 PF06553.12 KFL61734.1 - 0.096 12.4 1.1 0.13 11.9 1.1 1.2 1 0 0 1 1 1 0 BNIP3 Presenilin PF01080.17 KFL61734.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Presenilin Hit1_C PF18268.1 KFL61735.1 - 0.09 12.9 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Hit1 C-terminal Cytochrom_B559 PF00283.19 KFL61736.1 - 0.19 11.2 0.8 0.39 10.2 0.8 1.5 1 0 0 1 1 1 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits RasGEF PF00617.19 KFL61740.1 - 7.5e-44 150.0 0.1 1.9e-43 148.7 0.1 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFL61740.1 - 3.3e-13 49.8 0.0 8.5e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 KFL61740.1 - 0.0068 16.0 0.0 0.022 14.3 0.0 1.8 1 1 0 1 1 1 1 Ras family ATP_bind_1 PF03029.17 KFL61740.1 - 0.015 15.1 0.2 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KFL61740.1 - 0.027 14.9 0.1 0.23 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain PSP1 PF04468.12 KFL61741.1 - 8.8e-09 35.5 1.3 1.5e-08 34.8 1.3 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF2570 PF10828.8 KFL61741.1 - 5.8 6.8 6.6 1.8 8.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Cornichon PF03311.14 KFL61742.1 - 1.4e-40 138.4 8.8 1.7e-40 138.1 8.8 1.1 1 0 0 1 1 1 1 Cornichon protein Cornichon PF03311.14 KFL61743.1 - 3e-50 169.6 13.3 3.4e-50 169.4 13.3 1.0 1 0 0 1 1 1 1 Cornichon protein Cornichon PF03311.14 KFL61744.1 - 3e-50 169.6 13.3 3.4e-50 169.4 13.3 1.0 1 0 0 1 1 1 1 Cornichon protein Cornichon PF03311.14 KFL61745.1 - 1.5e-38 131.9 6.4 1.8e-38 131.6 6.4 1.1 1 0 0 1 1 1 1 Cornichon protein MFS_1 PF07690.16 KFL61746.1 - 6.2e-13 48.4 30.6 6.2e-13 48.4 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TerC PF03741.16 KFL61746.1 - 0.0065 16.2 0.3 0.0065 16.2 0.3 2.5 2 1 0 2 2 2 1 Integral membrane protein TerC family Ferlin_C PF16165.5 KFL61746.1 - 0.026 14.5 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 Ferlin C-terminus Ferlin_C PF16165.5 KFL61747.1 - 0.016 15.1 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 Ferlin C-terminus Sugar_tr PF00083.24 KFL61749.1 - 5e-06 25.6 0.1 6.4e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF5379 PF17350.2 KFL61749.1 - 0.028 14.7 0.4 0.034 14.4 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5379) FmiP_Thoc5 PF09766.9 KFL61751.1 - 3.3e-31 108.9 7.6 4e-31 108.6 7.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Casc1_N PF15927.5 KFL61751.1 - 0.0072 16.0 13.7 0.032 13.9 8.2 2.3 2 0 0 2 2 2 1 Cancer susceptibility candidate 1 N-terminus SPATA1_C PF15743.5 KFL61751.1 - 0.02 15.0 3.8 0.02 15.0 3.8 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus DUF948 PF06103.11 KFL61751.1 - 0.022 15.0 1.5 0.83 10.0 0.0 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 KFL61751.1 - 0.024 15.2 14.6 0.22 12.0 6.4 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4200 PF13863.6 KFL61751.1 - 0.032 14.6 13.1 0.05 14.0 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Flagellin_N PF00669.20 KFL61751.1 - 0.042 14.0 0.7 0.042 14.0 0.7 2.1 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region K-box PF01486.17 KFL61751.1 - 0.08 13.1 8.4 0.1 12.7 0.3 2.7 2 0 0 2 2 2 0 K-box region Trm5_N PF18093.1 KFL61751.1 - 0.13 12.2 6.5 13 5.7 0.1 3.5 3 0 0 3 3 3 0 tRNA methyltransferase 5 N-terminal domain HAUS-augmin3 PF14932.6 KFL61751.1 - 0.19 11.3 11.2 0.51 9.9 1.7 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF349 PF03993.12 KFL61751.1 - 0.28 11.5 10.1 0.041 14.2 5.0 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF4140 PF13600.6 KFL61751.1 - 1.2 9.6 8.7 4.5 7.8 0.2 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3450 PF11932.8 KFL61751.1 - 1.6 8.0 9.9 1.8 7.8 2.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) YabA PF06156.13 KFL61751.1 - 2.1 9.0 10.5 3.3 8.4 1.7 2.6 2 1 1 3 3 3 0 Initiation control protein YabA Mod_r PF07200.13 KFL61751.1 - 2.3 8.3 16.8 0.93 9.6 5.7 2.3 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein OmpH PF03938.14 KFL61751.1 - 3.5 8.0 13.0 0.84 10.0 4.7 2.3 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 KFL61751.1 - 5 7.0 12.4 1.1 9.1 0.4 2.7 2 1 0 2 2 2 0 Septum formation initiator FmiP_Thoc5 PF09766.9 KFL61752.1 - 2.7e-33 115.8 11.2 3.4e-33 115.4 11.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Casc1_N PF15927.5 KFL61752.1 - 0.0054 16.4 13.8 0.027 14.2 8.2 2.3 2 0 0 2 2 2 2 Cancer susceptibility candidate 1 N-terminus SPATA1_C PF15743.5 KFL61752.1 - 0.012 15.7 3.3 0.012 15.7 3.3 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus DUF948 PF06103.11 KFL61752.1 - 0.015 15.5 1.6 0.7 10.2 0.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF349 PF03993.12 KFL61752.1 - 0.035 14.4 5.0 0.035 14.4 5.0 2.3 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) Flagellin_N PF00669.20 KFL61752.1 - 0.035 14.2 0.7 0.035 14.2 0.7 2.1 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4200 PF13863.6 KFL61752.1 - 0.044 14.2 12.6 0.1 13.0 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 KFL61752.1 - 1.1 9.8 20.3 1.6 9.3 9.3 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF4140 PF13600.6 KFL61752.1 - 1.5 9.3 9.2 4.9 7.7 0.3 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 KFL61752.1 - 2 9.1 10.8 3 8.5 1.9 2.6 2 1 0 2 2 2 0 Initiation control protein YabA Mod_r PF07200.13 KFL61752.1 - 2.2 8.4 17.2 0.78 9.8 5.7 2.3 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Trm5_N PF18093.1 KFL61752.1 - 6.6 6.7 6.1 41 4.2 1.5 3.1 4 0 0 4 4 3 0 tRNA methyltransferase 5 N-terminal domain HAUS-augmin3 PF14932.6 KFL61752.1 - 7.8 6.0 17.2 4.6 6.7 3.1 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 NOT2_3_5 PF04153.18 KFL61753.1 - 4.9e-25 88.1 2.6 7e-25 87.6 0.1 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family CCDC53 PF10152.9 KFL61753.1 - 0.066 13.6 6.3 0.1 13.0 6.3 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex BORG_CEP PF14957.6 KFL61753.1 - 0.46 11.6 6.8 0.76 10.9 6.8 1.3 1 0 0 1 1 1 0 Cdc42 effector Presenilin PF01080.17 KFL61753.1 - 0.63 8.7 5.1 0.88 8.3 5.1 1.2 1 0 0 1 1 1 0 Presenilin DUF3275 PF11679.8 KFL61753.1 - 0.89 9.5 4.7 1.4 8.9 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) TFIIA PF03153.13 KFL61753.1 - 3.1 7.7 19.9 4.3 7.2 19.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4106 PF13388.6 KFL61753.1 - 4.8 6.3 14.8 6.6 5.8 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Lin-8 PF03353.15 KFL61753.1 - 8.6 5.8 9.1 12 5.4 9.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Consortin_C PF15281.6 KFL61754.1 - 0.22 11.5 0.5 0.3 11.1 0.5 1.1 1 0 0 1 1 1 0 Consortin C-terminus Aminotran_3 PF00202.21 KFL61756.1 - 8.7e-106 354.0 0.0 1.1e-105 353.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KFL61756.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase TPR_11 PF13414.6 KFL61758.1 - 6.6e-09 35.3 0.2 6.6e-09 35.3 0.2 1.9 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 KFL61758.1 - 1.3e-08 34.3 8.0 0.00013 21.8 1.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFL61758.1 - 1.8e-08 34.9 3.3 7.1e-05 23.4 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFL61758.1 - 1e-06 28.3 4.2 5.4e-05 22.8 1.5 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFL61758.1 - 1.2e-06 28.9 1.0 0.00072 20.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 KFL61758.1 - 6.3e-06 26.9 5.4 1.1e-05 26.1 5.4 1.4 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_14 PF13428.6 KFL61758.1 - 2.1e-05 25.0 0.1 0.29 12.0 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFL61758.1 - 2.4e-05 24.5 4.2 0.0061 16.8 1.0 2.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFL61758.1 - 0.0021 18.3 2.6 0.058 13.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFL61758.1 - 0.028 14.7 0.8 8.4 6.7 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FCH PF00611.23 KFL61758.1 - 0.13 12.6 1.3 0.31 11.3 0.4 2.0 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain TPR_10 PF13374.6 KFL61758.1 - 0.17 11.8 7.4 0.88 9.5 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFL61758.1 - 0.19 12.4 2.9 1.5 9.7 1.2 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFL61758.1 - 0.27 11.4 2.1 1.1 9.4 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFL61758.1 - 0.38 11.1 4.6 6.3 7.3 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFL61758.1 - 1.7 9.4 5.4 5.9 7.8 0.2 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF2434 PF10361.9 KFL61759.1 - 0.18 10.8 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) zf-H2C2_2 PF13465.6 KFL61762.1 - 4.3e-06 26.9 12.5 1.2e-05 25.5 1.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KFL61762.1 - 0.0001 22.5 4.6 0.00021 21.5 4.6 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KFL61762.1 - 0.00012 22.6 15.0 0.013 16.2 5.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFL61762.1 - 0.00091 19.5 4.8 0.061 13.6 1.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFL61762.1 - 0.017 15.5 14.5 0.089 13.3 7.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 KFL61762.1 - 0.37 11.2 5.0 3.3 8.2 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 KFL61762.1 - 8.6 6.1 6.3 36 4.1 0.6 3.4 3 0 0 3 3 3 0 MYST family zinc finger domain zf-H2C2_2 PF13465.6 KFL61763.1 - 4.3e-06 26.9 12.6 1.2e-05 25.6 1.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KFL61763.1 - 9.9e-05 22.6 4.6 0.0002 21.6 4.6 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KFL61763.1 - 0.00011 22.7 15.0 0.013 16.3 5.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFL61763.1 - 0.00084 19.6 4.8 0.058 13.7 1.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFL61763.1 - 0.017 15.6 14.5 0.085 13.3 7.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 KFL61763.1 - 0.35 11.3 5.0 3.1 8.3 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFL61764.1 - 4.3e-06 26.9 12.6 1.2e-05 25.6 1.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KFL61764.1 - 9.9e-05 22.6 4.6 0.0002 21.6 4.6 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KFL61764.1 - 0.00011 22.7 15.0 0.013 16.3 5.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFL61764.1 - 0.00084 19.6 4.8 0.058 13.7 1.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFL61764.1 - 0.017 15.6 14.5 0.085 13.3 7.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 KFL61764.1 - 0.35 11.3 5.0 3.1 8.3 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFL61765.1 - 4.3e-06 26.9 12.6 1.2e-05 25.6 1.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KFL61765.1 - 9.9e-05 22.6 4.6 0.0002 21.6 4.6 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KFL61765.1 - 0.00011 22.7 15.0 0.013 16.3 5.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFL61765.1 - 0.00084 19.6 4.8 0.058 13.7 1.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFL61765.1 - 0.017 15.6 14.5 0.085 13.3 7.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 KFL61765.1 - 0.35 11.3 5.0 3.1 8.3 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type eIF-5a PF01287.20 KFL61769.1 - 3.4e-19 68.7 0.5 5.2e-19 68.1 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KFL61769.1 - 0.0018 18.2 0.2 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Lactamase_B_5 PF14597.6 KFL61769.1 - 0.056 12.9 0.0 0.07 12.6 0.0 1.1 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily zf-RRN7 PF11781.8 KFL61770.1 - 5.5e-08 32.3 3.9 9e-08 31.7 3.9 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PPV_E1_N PF00524.18 KFL61770.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 E1 Protein, N terminal domain Tli4_C PF18426.1 KFL61771.1 - 0.11 12.8 0.4 0.15 12.4 0.4 1.2 1 0 0 1 1 1 0 Tle cognate immunity protein 4 C-terminal domain GTP_EFTU PF00009.27 KFL61772.1 - 2.7e-34 118.4 0.1 4.6e-33 114.4 0.1 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFL61772.1 - 6.3e-21 74.5 0.1 1.9e-20 72.9 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KFL61772.1 - 2.4e-10 40.6 1.4 7.2e-10 39.1 0.1 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFL61772.1 - 4e-07 30.1 0.5 9.3e-06 25.7 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 KFL61772.1 - 0.00049 20.3 0.0 0.0017 18.5 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KFL61772.1 - 0.0049 16.7 0.0 0.023 14.5 0.0 2.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 KFL61772.1 - 0.049 13.2 0.0 0.22 11.1 0.0 2.3 1 1 0 1 1 1 0 Ras family GTP_EFTU_D4 PF14578.6 KFL61772.1 - 0.11 12.4 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 SRP68 PF16969.5 KFL61773.1 - 4.3e-157 524.5 0.2 4.8e-157 524.3 0.2 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 CENP-O PF09496.10 KFL61773.1 - 0.029 14.4 0.3 3.8 7.4 0.0 2.8 1 1 1 2 2 2 0 Cenp-O kinetochore centromere component PPR PF01535.20 KFL61774.1 - 3.4e-20 70.8 2.3 0.0001 22.3 0.0 8.5 8 0 0 8 8 8 5 PPR repeat PPR_2 PF13041.6 KFL61774.1 - 6.9e-18 64.6 5.9 4.2e-09 36.5 0.0 6.8 4 1 3 7 7 7 2 PPR repeat family PPR_3 PF13812.6 KFL61774.1 - 7.3e-18 64.4 0.6 3.2e-07 30.3 0.0 5.5 3 2 2 5 5 5 4 Pentatricopeptide repeat domain PPR_long PF17177.4 KFL61774.1 - 2.2e-12 46.8 0.0 3.9e-06 26.4 0.0 3.3 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KFL61774.1 - 7.7e-07 28.7 0.0 2.8 7.7 0.0 5.8 6 0 0 6 6 6 2 PPR repeat DUF3384 PF11864.8 KFL61774.1 - 0.071 12.0 1.3 0.21 10.4 0.0 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF3384) MLTR_LBD PF17765.1 KFL61774.1 - 0.26 11.4 2.3 4.1 7.5 0.0 2.9 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain Solute_trans_a PF03619.16 KFL61778.1 - 2.7e-82 276.3 5.2 3.3e-82 276.0 5.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Podoplanin PF05808.11 KFL61778.1 - 1.2 9.3 2.8 2 8.5 2.8 1.3 1 0 0 1 1 1 0 Podoplanin Bunya_G2 PF03563.13 KFL61781.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 SecY PF00344.20 KFL61781.1 - 0.25 10.6 3.8 0.35 10.1 3.8 1.1 1 0 0 1 1 1 0 SecY translocase Lactamase_B_2 PF12706.7 KFL61788.1 - 0.002 17.7 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFL61788.1 - 0.14 12.0 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ketoacyl-synt_C PF02801.22 KFL61789.1 - 2.1e-30 105.1 0.7 3.2e-30 104.5 0.7 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 KFL61789.1 - 2.5e-14 53.5 0.6 6.9e-13 48.8 0.1 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Thiolase_C PF02803.18 KFL61789.1 - 0.004 16.8 0.3 0.004 16.8 0.3 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain Ras PF00071.22 KFL61790.1 - 8.9e-53 178.2 0.0 1e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL61790.1 - 6.1e-19 68.4 0.0 8.7e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL61790.1 - 4.4e-06 26.3 0.0 6.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Vint PF14623.6 KFL61791.1 - 3.8e-61 205.7 0.0 4.7e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 KFL61791.1 - 1.6e-06 28.1 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like Nicastrin PF05450.15 KFL61792.1 - 0.16 11.4 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Nicastrin Ecl1 PF12855.7 KFL61793.1 - 1.1e-17 65.7 14.7 1.4e-17 65.4 14.7 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KFL61793.1 - 0.52 10.4 7.2 0.92 9.7 7.2 1.4 1 0 0 1 1 1 0 MYND finger DUF2256 PF10013.9 KFL61793.1 - 1.1 9.4 7.3 0.36 11.0 0.9 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) MT-A70 PF05063.14 KFL61794.1 - 5.5e-14 52.5 0.0 8.6e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 MT-A70 KR PF08659.10 KFL61796.1 - 8.5e-17 61.6 0.0 1.1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KFL61796.1 - 0.041 13.3 0.0 0.075 12.5 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase PS-DH PF14765.6 KFL61797.1 - 6.6e-14 51.8 0.1 2.3e-13 50.1 0.1 1.8 1 1 1 2 2 2 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.26 KFL61797.1 - 7e-06 26.0 0.2 1.4e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFL61797.1 - 0.0048 16.8 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KFL61797.1 - 0.008 15.5 2.0 0.014 14.7 2.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ketoacyl-synt PF00109.26 KFL61798.1 - 2.1e-12 47.2 0.0 2.2e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ETC_C1_NDUFA4 PF04800.12 KFL61799.1 - 1.3e-36 124.7 2.3 1.6e-36 124.4 2.3 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region Methyltransf_11 PF08241.12 KFL61800.1 - 9.3e-06 26.2 0.0 1.9e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFL61800.1 - 0.0029 18.3 0.0 0.0097 16.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFL61800.1 - 0.0037 16.6 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFL61801.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CLTH PF10607.9 KFL61802.1 - 2.4e-33 115.1 0.3 3.3e-33 114.7 0.3 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFL61802.1 - 2e-09 37.1 0.0 4.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 LisH CLTH PF10607.9 KFL61803.1 - 1.8e-33 115.6 0.3 2.2e-33 115.2 0.3 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFL61803.1 - 9.6e-05 22.2 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 LisH PRK PF00485.18 KFL61804.1 - 7.6e-37 127.0 0.0 1e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KFL61804.1 - 9.7e-06 26.2 0.0 1.3e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFL61804.1 - 9.8e-05 21.7 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.17 KFL61804.1 - 0.0075 16.4 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain CPT PF07931.12 KFL61804.1 - 0.0084 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein CbiA PF01656.23 KFL61804.1 - 0.037 14.1 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cytidylate_kin PF02224.18 KFL61804.1 - 0.045 13.5 0.0 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 KFL61804.1 - 0.085 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFL61804.1 - 0.1 13.1 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 KFL61804.1 - 0.16 11.8 0.0 0.9 9.4 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 KFL61804.1 - 0.2 11.7 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 KFL61804.1 - 0.23 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PRK PF00485.18 KFL61805.1 - 7.6e-37 127.0 0.0 1e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KFL61805.1 - 9.7e-06 26.2 0.0 1.3e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFL61805.1 - 9.8e-05 21.7 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.17 KFL61805.1 - 0.0075 16.4 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain CPT PF07931.12 KFL61805.1 - 0.0084 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein CbiA PF01656.23 KFL61805.1 - 0.037 14.1 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cytidylate_kin PF02224.18 KFL61805.1 - 0.045 13.5 0.0 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 KFL61805.1 - 0.085 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFL61805.1 - 0.1 13.1 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 KFL61805.1 - 0.16 11.8 0.0 0.9 9.4 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 KFL61805.1 - 0.2 11.7 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 KFL61805.1 - 0.23 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Sec1 PF00995.23 KFL61806.1 - 3.5e-42 145.4 0.0 5.2e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Sec1 family Glyco_transf_15 PF01793.16 KFL61807.1 - 1.3e-127 425.5 11.2 1.7e-127 425.2 11.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SIC PF03482.13 KFL61807.1 - 0.0049 17.0 0.7 0.012 15.8 0.7 1.7 1 0 0 1 1 1 1 sic protein repeat FAP PF07174.11 KFL61807.1 - 0.11 12.0 9.2 0.15 11.5 9.2 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Glyco_transf_15 PF01793.16 KFL61808.1 - 7.6e-90 301.4 6.0 9.9e-90 301.1 6.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SIC PF03482.13 KFL61808.1 - 0.0035 17.5 0.7 0.0086 16.2 0.7 1.7 1 0 0 1 1 1 1 sic protein repeat FAP PF07174.11 KFL61808.1 - 0.07 12.6 9.3 0.099 12.1 9.3 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Glyco_transf_15 PF01793.16 KFL61809.1 - 7.6e-90 301.4 6.0 9.9e-90 301.1 6.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SIC PF03482.13 KFL61809.1 - 0.0035 17.5 0.7 0.0086 16.2 0.7 1.7 1 0 0 1 1 1 1 sic protein repeat FAP PF07174.11 KFL61809.1 - 0.07 12.6 9.3 0.099 12.1 9.3 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) SH3_9 PF14604.6 KFL61811.1 - 9e-06 25.5 0.2 1.7e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFL61811.1 - 0.00023 20.7 0.1 0.00043 19.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61811.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.6 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61811.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61811.1 - 0.22 11.0 1.2 0.43 10.0 1.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KFL61812.1 - 1.6e-05 24.7 1.7 1.7e-05 24.6 0.2 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFL61812.1 - 0.00023 20.7 0.1 0.00042 19.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61812.1 - 0.013 15.0 0.0 0.027 13.9 0.0 1.5 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61812.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61812.1 - 0.22 11.0 1.2 0.42 10.1 1.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KFL61813.1 - 1.6e-05 24.7 1.7 1.7e-05 24.6 0.2 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFL61813.1 - 0.00023 20.7 0.1 0.00042 19.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61813.1 - 0.012 15.0 0.0 0.027 13.9 0.0 1.6 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61813.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61813.1 - 0.21 11.0 1.2 0.41 10.1 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KFL61814.1 - 8.6e-06 25.5 0.2 1.6e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFL61814.1 - 0.00022 20.7 0.1 0.00041 19.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61814.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.6 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61814.1 - 0.024 14.5 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61814.1 - 0.21 11.0 1.2 0.41 10.1 1.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KFL61815.1 - 8.6e-06 25.5 0.2 1.6e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFL61815.1 - 0.00022 20.8 0.1 0.0004 19.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61815.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.6 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61815.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61815.1 - 0.2 11.1 1.2 0.4 10.1 1.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KFL61816.1 - 1.4e-05 24.8 1.7 1.6e-05 24.7 0.2 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFL61816.1 - 0.00021 20.8 0.1 0.0004 19.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61816.1 - 0.012 15.1 0.0 0.025 14.0 0.0 1.6 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61816.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61816.1 - 0.2 11.1 1.2 0.39 10.2 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KFL61817.1 - 8.1e-06 25.6 0.2 1.5e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFL61817.1 - 0.00021 20.9 0.1 0.00038 20.0 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61817.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.6 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61817.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61817.1 - 0.2 11.1 1.2 0.38 10.2 1.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KFL61818.1 - 9.5e-06 25.4 1.5 1.2e-05 25.0 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFL61818.1 - 0.00017 21.2 0.1 0.00031 20.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61818.1 - 0.0083 15.6 0.0 0.019 14.4 0.0 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61818.1 - 0.019 14.9 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61818.1 - 0.15 11.5 1.2 0.31 10.5 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KFL61819.1 - 9.5e-06 25.4 1.5 1.2e-05 25.0 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFL61819.1 - 0.00017 21.2 0.1 0.00031 20.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61819.1 - 0.0083 15.6 0.0 0.019 14.4 0.0 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61819.1 - 0.019 14.9 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61819.1 - 0.15 11.5 1.2 0.31 10.5 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KFL61820.1 - 9.5e-06 25.4 1.5 1.2e-05 25.0 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFL61820.1 - 0.00017 21.2 0.1 0.00031 20.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61820.1 - 0.0083 15.6 0.0 0.019 14.4 0.0 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61820.1 - 0.019 14.9 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61820.1 - 0.15 11.5 1.2 0.31 10.5 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KFL61821.1 - 9.5e-06 25.4 1.5 1.2e-05 25.0 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFL61821.1 - 0.00017 21.2 0.1 0.00031 20.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61821.1 - 0.0083 15.6 0.0 0.019 14.4 0.0 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61821.1 - 0.019 14.9 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61821.1 - 0.15 11.5 1.2 0.31 10.5 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KFL61822.1 - 6.4e-06 25.9 0.2 1.2e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFL61822.1 - 0.00016 21.2 0.1 0.0003 20.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61822.1 - 0.0077 15.7 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61822.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61822.1 - 0.15 11.5 1.2 0.3 10.5 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KFL61823.1 - 6.4e-06 25.9 0.2 1.2e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFL61823.1 - 0.00016 21.2 0.1 0.0003 20.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61823.1 - 0.0077 15.7 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61823.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61823.1 - 0.15 11.5 1.2 0.3 10.5 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KFL61824.1 - 6.4e-06 25.9 0.2 1.2e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFL61824.1 - 0.00016 21.2 0.1 0.0003 20.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KFL61824.1 - 0.0077 15.7 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Syndecan PF01034.20 KFL61824.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFL61824.1 - 0.15 11.5 1.2 0.3 10.5 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ribosomal_L7Ae PF01248.26 KFL61829.1 - 1.6e-25 88.6 0.0 1.9e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KFL61829.1 - 0.0002 21.4 0.1 0.00024 21.2 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KFL61829.1 - 0.0022 17.8 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain PHM7_ext PF12621.8 KFL61830.1 - 7.1e-30 103.0 0.0 1.1e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RSN1_7TM PF02714.15 KFL61830.1 - 2.1e-29 102.7 3.3 2.1e-29 102.7 3.3 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate DUF4131 PF13567.6 KFL61830.1 - 0.032 13.9 2.9 0.49 10.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) EXS PF03124.14 KFL61830.1 - 0.3 10.4 2.7 0.38 10.0 2.7 1.1 1 0 0 1 1 1 0 EXS family RSN1_TM PF13967.6 KFL61831.1 - 9.2e-43 145.7 1.3 9.2e-43 145.7 1.3 2.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFL61831.1 - 2.3e-37 128.9 0.0 3.3e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 KFL61831.1 - 1.3e-20 73.9 6.7 1.7e-18 67.0 4.9 2.5 2 0 0 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate Syndecan PF01034.20 KFL61831.1 - 7.4 6.6 5.6 20 5.2 1.1 2.5 2 0 0 2 2 2 0 Syndecan domain Acyltransferase PF01553.21 KFL61833.1 - 1.4e-17 63.6 0.0 2.4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.21 KFL61834.1 - 2.8e-05 23.8 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Cdc13_OB2 PF18691.1 KFL61834.1 - 0.15 12.1 0.3 4.9 7.3 0.0 2.7 3 0 0 3 3 3 0 Cell division control protein 13, OB2 domain Acyltransferase PF01553.21 KFL61835.1 - 2.8e-05 23.8 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Cdc13_OB2 PF18691.1 KFL61835.1 - 0.15 12.1 0.3 4.9 7.3 0.0 2.7 3 0 0 3 3 3 0 Cell division control protein 13, OB2 domain Pantoate_ligase PF02569.15 KFL61836.1 - 3.7e-89 298.5 0.0 6.1e-89 297.8 0.0 1.3 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.29 KFL61836.1 - 3.5e-40 137.6 0.5 6.1e-40 136.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFL61836.1 - 8.8e-21 74.3 0.0 4.3e-20 72.1 0.0 2.1 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFL61836.1 - 1.2e-18 67.0 0.0 2.6e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFL61836.1 - 1.7e-06 28.1 0.0 6.7e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFL61836.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase MFS_1 PF07690.16 KFL61837.1 - 7.4e-18 64.6 11.1 8.2e-18 64.4 11.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KFL61838.1 - 1.7e-08 33.8 10.6 2.2e-08 33.5 10.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFL61838.1 - 0.056 12.3 1.5 0.12 11.2 1.4 1.7 1 1 0 1 1 1 0 MFS_1 like family DUF4227 PF14004.6 KFL61838.1 - 0.14 12.1 0.1 8.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) DUF1772 PF08592.11 KFL61838.1 - 0.72 10.2 8.1 2.5 8.4 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Bax1-I PF01027.20 KFL61838.1 - 6.7 6.5 12.5 8.3 6.2 10.1 2.0 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Rhomboid PF01694.22 KFL61838.1 - 6.8 6.7 9.0 4.4 7.3 3.3 2.3 1 1 0 2 2 2 0 Rhomboid family DUF4672 PF15716.5 KFL61839.1 - 0.0039 16.8 1.4 0.0052 16.4 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4672) Metallophos PF00149.28 KFL61844.1 - 1.1e-36 127.2 0.3 1.6e-36 126.8 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFL61844.1 - 0.063 13.7 0.3 0.18 12.2 0.3 1.9 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Rho_GDI PF02115.17 KFL61845.1 - 2.1e-61 207.1 0.1 3.2e-59 200.0 0.1 2.0 1 1 0 1 1 1 1 RHO protein GDP dissociation inhibitor Rho_GDI PF02115.17 KFL61846.1 - 9.5e-57 191.9 0.0 1.7e-54 184.6 0.0 2.0 1 1 0 1 1 1 1 RHO protein GDP dissociation inhibitor Rho_GDI PF02115.17 KFL61847.1 - 2e-64 216.9 0.1 2.2e-64 216.8 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Rho_GDI PF02115.17 KFL61848.1 - 9.5e-60 201.7 0.0 1.1e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Rho_GDI PF02115.17 KFL61849.1 - 3.2e-37 128.2 0.0 3.7e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.13 KFL61850.1 - 0.024 14.5 0.9 1.9 8.3 0.0 3.0 2 1 1 3 3 3 0 KilA-N domain DUF4746 PF15928.5 KFL61850.1 - 8.5 5.7 24.0 0.093 12.1 9.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4746) DUF4746 PF15928.5 KFL61851.1 - 5 6.5 24.0 0.066 12.6 9.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4746) RF-1 PF00472.20 KFL61851.1 - 7.8 6.5 12.5 0.35 10.8 0.6 2.5 2 1 0 2 2 2 0 RF-1 domain RF-1 PF00472.20 KFL61852.1 - 7.4 6.5 12.6 0.34 10.9 0.6 2.5 2 1 0 2 2 2 0 RF-1 domain APH PF01636.23 KFL61853.1 - 1.8e-08 34.6 0.0 4.1e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFL61853.1 - 4.6e-05 23.1 0.0 7.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KFL61853.1 - 0.00027 20.4 0.0 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 KFL61853.1 - 0.031 13.9 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KFL61853.1 - 0.056 12.7 0.0 0.3 10.3 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase Fructosamin_kin PF03881.14 KFL61853.1 - 0.095 11.9 0.0 5.5 6.1 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.20 KFL61853.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 KFL61853.1 - 0.24 10.2 0.0 0.54 9.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ank_2 PF12796.7 KFL61856.1 - 1.2e-25 89.9 0.2 2.2e-07 31.4 0.5 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFL61856.1 - 4.8e-24 84.4 0.7 2.6e-08 34.3 0.1 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KFL61856.1 - 8.1e-18 64.0 3.8 0.0025 18.2 0.0 5.9 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KFL61856.1 - 3.8e-15 55.8 0.1 2.3e-05 24.6 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFL61856.1 - 6.9e-15 53.7 0.6 0.022 15.3 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 KFL61857.1 - 1.1e-25 89.9 0.2 2.1e-07 31.4 0.5 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFL61857.1 - 4.2e-24 84.6 0.7 2.5e-08 34.3 0.1 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KFL61857.1 - 7.5e-18 64.1 3.9 0.0025 18.2 0.0 5.9 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KFL61857.1 - 3.4e-15 55.9 0.1 2.2e-05 24.6 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFL61857.1 - 6e-15 53.9 0.6 0.021 15.3 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 KFL61858.1 - 1.1e-25 90.0 0.2 2.1e-07 31.4 0.5 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFL61858.1 - 4.2e-24 84.6 0.7 2.5e-08 34.3 0.1 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KFL61858.1 - 7.3e-18 64.1 3.9 0.0025 18.2 0.0 5.9 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KFL61858.1 - 3.3e-15 55.9 0.1 2.2e-05 24.6 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFL61858.1 - 5.8e-15 53.9 0.6 0.021 15.3 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat PRMT5_TIM PF17285.2 KFL61859.1 - 2e-71 240.2 0.0 3.1e-71 239.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KFL61859.1 - 3.8e-65 219.0 0.0 5.5e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KFL61859.1 - 8.7e-39 133.2 0.4 2.1e-38 132.0 0.4 1.6 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Mlh1_C PF16413.5 KFL61860.1 - 2.1e-104 348.7 0.0 2.5e-104 348.4 0.0 1.0 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus Tgi2PP PF18250.1 KFL61862.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Effector immunity protein Tgi2PP RPN1_RPN2_N PF17781.1 KFL61863.1 - 6.4e-118 393.6 4.4 1.2e-117 392.8 4.4 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KFL61863.1 - 6.4e-26 90.2 0.0 1.3e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KFL61863.1 - 1.1e-20 72.9 12.9 7.3e-05 23.0 0.1 8.2 7 0 0 7 7 7 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFL61863.1 - 0.0033 17.8 1.9 3.9 7.9 0.0 4.3 5 2 1 6 6 6 2 HEAT repeats RPN1_RPN2_N PF17781.1 KFL61864.1 - 1e-102 343.7 3.2 1.9e-102 342.8 3.2 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KFL61864.1 - 5.9e-26 90.3 0.0 1.1e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KFL61864.1 - 4.8e-20 70.9 16.1 6.5e-05 23.2 0.1 8.3 7 1 0 7 7 7 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFL61864.1 - 0.004 17.5 1.6 2.9 8.4 0.0 3.9 4 2 1 5 5 5 3 HEAT repeats RPN1_RPN2_N PF17781.1 KFL61865.1 - 1e-102 343.7 3.2 1.9e-102 342.8 3.2 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KFL61865.1 - 5.9e-26 90.3 0.0 1.1e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KFL61865.1 - 4.8e-20 70.9 16.1 6.5e-05 23.2 0.1 8.3 7 1 0 7 7 7 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFL61865.1 - 0.004 17.5 1.6 2.9 8.4 0.0 3.9 4 2 1 5 5 5 3 HEAT repeats Pyr_redox_2 PF07992.14 KFL61866.1 - 1.1e-52 179.2 0.1 1.4e-52 178.8 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFL61866.1 - 2.1e-10 41.0 0.0 3.5e-09 37.1 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFL61866.1 - 0.004 16.5 0.1 3.8 6.7 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EcoR124_C PF12008.8 KFL61866.1 - 0.025 14.2 0.8 0.079 12.6 0.0 1.9 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal PRIMA1 PF16101.5 KFL61866.1 - 0.49 10.5 7.5 1.1 9.3 7.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Acetyltransf_1 PF00583.25 KFL61867.1 - 5.4e-10 39.5 0.0 9.3e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFL61867.1 - 7.2e-10 38.9 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFL61867.1 - 8e-10 39.0 0.1 1.5e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFL61867.1 - 3.5e-06 27.1 0.0 0.0036 17.4 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFL61867.1 - 1.7e-05 24.7 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KFL61867.1 - 0.011 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GATase_4 PF13230.6 KFL61869.1 - 0.0016 17.4 0.0 0.38 9.6 0.0 2.1 1 1 1 2 2 2 2 Glutamine amidotransferases class-II Med26 PF08711.11 KFL61871.1 - 8e-10 38.6 0.0 1.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Med26 PF08711.11 KFL61872.1 - 4.4e-10 39.4 0.0 1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF5372 PF17342.2 KFL61872.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5372) Ank_2 PF12796.7 KFL61873.1 - 5e-24 84.7 0.3 9.3e-13 48.6 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFL61873.1 - 1.6e-23 82.8 1.7 5e-09 36.5 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFL61873.1 - 2.3e-20 72.4 0.1 3.2e-09 36.8 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFL61873.1 - 1.4e-15 55.8 0.2 0.0032 17.8 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KFL61873.1 - 1.2e-10 41.3 1.1 0.0012 19.2 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Shal-type PF11601.8 KFL61873.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels, N-terminal V-ATPase_H_N PF03224.14 KFL61875.1 - 5.2e-56 190.2 0.0 5.8e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit H Med4 PF10018.9 KFL61875.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 V-ATPase_H_C PF11698.8 KFL61876.1 - 2.4e-36 124.4 0.0 3.5e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 KFL61876.1 - 0.0017 17.7 0.2 0.0053 16.1 0.2 1.7 2 0 0 2 2 2 1 V-ATPase subunit H HAD_2 PF13419.6 KFL61880.1 - 7.2e-14 52.3 0.0 1e-13 51.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFL61880.1 - 2.1e-07 31.4 0.0 1.6e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFL61880.1 - 0.00023 21.1 0.1 0.00066 19.7 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KFL61880.1 - 0.025 14.7 0.0 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.11 KFL61881.1 - 2.3e-25 88.5 16.5 7.1e-25 86.9 16.8 1.7 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase DUF3580 PF12117.8 KFL61882.1 - 0.0085 16.3 0.1 0.0093 16.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3580) Med16 PF11635.8 KFL61883.1 - 1.1e-24 86.4 0.0 1.5e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Med16 PF11635.8 KFL61884.1 - 9.4e-135 450.4 0.0 1.1e-134 450.2 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Ribosomal_L29 PF00831.23 KFL61885.1 - 5.1e-18 64.8 0.3 5.1e-18 64.8 0.3 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein Cortex-I_coil PF09304.10 KFL61885.1 - 0.21 11.8 4.8 0.32 11.2 1.8 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil CorA PF01544.18 KFL61885.1 - 0.31 10.3 2.1 0.38 10.0 2.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V-SNARE_C PF12352.8 KFL61886.1 - 5.3e-16 58.7 6.1 2.5e-15 56.5 0.1 2.5 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFL61886.1 - 0.022 14.7 0.6 4.2 7.4 0.0 2.4 2 1 1 3 3 3 0 Sec20 DUF4570 PF15134.6 KFL61886.1 - 0.76 9.8 5.7 1.6 8.8 5.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) RNase_PH_C PF03725.15 KFL61888.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PGK PF00162.19 KFL61889.1 - 1.4e-125 419.2 0.5 1.6e-125 419.0 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FIVAR PF07554.13 KFL61889.1 - 0.11 13.3 0.0 20 6.0 0.0 3.1 4 0 0 4 4 4 0 FIVAR domain DUF3530 PF12048.8 KFL61889.1 - 0.16 11.3 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) PGK PF00162.19 KFL61890.1 - 6.3e-84 282.1 1.6 6.9e-84 282.0 1.6 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FIVAR PF07554.13 KFL61890.1 - 0.071 13.9 0.1 12 6.7 0.0 2.7 3 0 0 3 3 3 0 FIVAR domain DUF3530 PF12048.8 KFL61890.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) ABC_tran PF00005.27 KFL61891.1 - 5.3e-34 117.7 0.0 1.8e-15 57.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFL61891.1 - 3.6e-11 42.9 2.4 0.0029 17.1 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFL61891.1 - 3.4e-09 36.9 6.0 0.31 10.8 1.8 4.5 3 2 2 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KFL61891.1 - 1.8e-06 28.0 0.0 0.045 13.7 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA PF00004.29 KFL61891.1 - 1.8e-05 25.2 0.1 0.021 15.3 0.1 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KFL61891.1 - 3.1e-05 23.9 0.4 0.22 11.2 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KFL61891.1 - 4.5e-05 23.8 0.0 0.0094 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain RLI PF04068.15 KFL61891.1 - 7.4e-05 22.5 4.4 7.4e-05 22.5 4.4 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 KFL61891.1 - 8.4e-05 22.2 2.5 8.4e-05 22.2 2.5 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.6 KFL61891.1 - 0.00013 22.4 0.0 0.037 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KFL61891.1 - 0.00034 20.2 1.1 0.0035 16.9 0.2 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KFL61891.1 - 0.00046 20.5 0.0 0.25 11.7 0.0 2.8 3 0 0 3 3 2 1 RNA helicase RsgA_GTPase PF03193.16 KFL61891.1 - 0.00056 19.9 0.2 0.95 9.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFL61891.1 - 0.0012 18.5 0.4 0.96 9.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KFL61891.1 - 0.0012 19.4 0.1 2.1 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFL61891.1 - 0.0018 18.1 2.1 0.12 12.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 KFL61891.1 - 0.0026 17.9 8.6 0.0052 16.9 8.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain SRP54 PF00448.22 KFL61891.1 - 0.0028 17.3 2.9 0.063 12.9 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain TsaE PF02367.17 KFL61891.1 - 0.0054 16.7 0.1 0.087 12.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFL61891.1 - 0.0062 16.5 2.1 0.31 10.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 KFL61891.1 - 0.0062 15.7 1.6 1.6 7.9 0.0 3.4 3 1 1 4 4 4 1 NB-ARC domain Fer4_6 PF12837.7 KFL61891.1 - 0.0089 16.1 2.2 0.0089 16.1 2.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Thymidylate_kin PF02223.17 KFL61891.1 - 0.0091 15.7 0.2 4.8 6.8 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase AAA_33 PF13671.6 KFL61891.1 - 0.012 15.8 0.1 2 8.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFL61891.1 - 0.014 15.1 0.4 0.66 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_10 PF13237.6 KFL61891.1 - 0.027 14.6 1.6 0.027 14.6 1.6 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_23 PF13476.6 KFL61891.1 - 0.027 15.0 2.7 0.6 10.6 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFL61891.1 - 0.029 14.4 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KFL61891.1 - 0.029 14.6 0.1 4.5 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 KFL61891.1 - 0.033 14.4 8.9 0.072 13.3 8.9 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain TniB PF05621.11 KFL61891.1 - 0.063 12.7 0.1 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein VirE PF05272.11 KFL61891.1 - 0.068 12.9 0.0 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E AAA_13 PF13166.6 KFL61891.1 - 0.068 11.8 1.0 0.073 11.7 0.0 1.5 2 0 0 2 2 1 0 AAA domain Fer4_16 PF13484.6 KFL61891.1 - 0.085 13.8 0.2 0.085 13.8 0.2 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain DnaB_C PF03796.15 KFL61891.1 - 0.11 11.8 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Fer4_17 PF13534.6 KFL61891.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain ATPase PF06745.13 KFL61891.1 - 0.19 11.1 0.1 0.41 9.9 0.1 1.5 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.9 KFL61891.1 - 0.28 10.9 2.3 0.3 10.8 0.1 2.2 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Fer4_7 PF12838.7 KFL61891.1 - 0.3 11.7 9.1 1.2 9.7 9.4 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 KFL61891.1 - 0.42 10.5 3.2 4.7 7.1 0.1 2.8 3 0 0 3 3 2 0 NTPase Fer4_8 PF13183.6 KFL61891.1 - 4.6 7.8 10.6 1.7 9.2 2.2 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KFL61891.1 - 9.6 6.5 8.7 0.29 11.3 1.2 2.3 2 0 0 2 2 1 0 4Fe-4S binding domain ABC_tran PF00005.27 KFL61892.1 - 3.6e-34 118.2 0.0 1.4e-15 58.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KFL61892.1 - 3e-14 52.6 5.5 3e-14 52.6 5.5 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KFL61892.1 - 1.9e-11 43.8 2.3 0.0024 17.3 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFL61892.1 - 2.8e-09 37.2 6.6 0.31 10.8 2.0 4.5 3 2 2 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KFL61892.1 - 1.2e-06 28.6 0.0 0.038 13.9 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA PF00004.29 KFL61892.1 - 1.3e-05 25.6 0.1 0.018 15.5 0.1 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KFL61892.1 - 2e-05 24.5 0.4 0.19 11.4 0.0 3.0 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KFL61892.1 - 3.3e-05 24.2 0.0 0.0077 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.27 KFL61892.1 - 7.3e-05 22.4 2.5 7.3e-05 22.4 2.5 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_16 PF13191.6 KFL61892.1 - 9.2e-05 22.9 0.0 0.028 14.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KFL61892.1 - 0.00021 20.8 0.8 0.003 17.1 0.2 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KFL61892.1 - 0.00024 21.4 0.2 0.22 12.0 0.0 3.2 4 0 0 4 4 2 1 RNA helicase RsgA_GTPase PF03193.16 KFL61892.1 - 0.0004 20.3 0.2 0.81 9.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KFL61892.1 - 0.00092 19.8 0.1 1.7 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFL61892.1 - 0.001 18.8 0.6 0.82 9.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KFL61892.1 - 0.0015 18.3 2.1 0.1 12.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KFL61892.1 - 0.0021 17.7 2.9 0.055 13.1 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_21 PF14697.6 KFL61892.1 - 0.0024 17.9 11.4 0.0048 17.0 11.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KFL61892.1 - 0.0034 17.4 12.3 0.0077 16.3 2.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain NB-ARC PF00931.22 KFL61892.1 - 0.004 16.4 1.6 1.3 8.1 0.0 3.4 3 1 1 4 4 4 1 NB-ARC domain TsaE PF02367.17 KFL61892.1 - 0.0041 17.1 0.1 0.074 13.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFL61892.1 - 0.0044 17.0 2.1 0.27 11.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.17 KFL61892.1 - 0.0063 16.2 0.2 4.1 7.0 0.0 3.0 3 0 0 3 3 3 1 Thymidylate kinase AAA_33 PF13671.6 KFL61892.1 - 0.0092 16.1 0.1 1.8 8.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFL61892.1 - 0.012 15.4 0.6 0.56 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFL61892.1 - 0.02 14.9 0.1 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KFL61892.1 - 0.021 15.4 2.8 0.51 10.8 0.2 2.5 2 0 0 2 2 2 0 AAA domain Fer4_10 PF13237.6 KFL61892.1 - 0.022 14.9 1.5 0.022 14.9 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_28 PF13521.6 KFL61892.1 - 0.022 15.0 0.1 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KFL61892.1 - 0.043 12.5 0.6 0.06 12.0 0.0 1.5 2 0 0 2 2 1 0 AAA domain TniB PF05621.11 KFL61892.1 - 0.047 13.1 0.1 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein VirE PF05272.11 KFL61892.1 - 0.052 13.3 0.0 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_16 PF13484.6 KFL61892.1 - 0.074 14.0 0.2 0.074 14.0 0.2 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain DnaB_C PF03796.15 KFL61892.1 - 0.082 12.2 0.0 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Fer4_9 PF13187.6 KFL61892.1 - 0.084 13.1 11.5 0.18 12.0 11.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KFL61892.1 - 0.11 13.0 0.2 0.11 13.0 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain ATPase PF06745.13 KFL61892.1 - 0.16 11.3 0.1 0.35 10.2 0.1 1.5 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.9 KFL61892.1 - 0.21 11.3 2.3 0.26 11.0 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KFL61892.1 - 0.27 11.1 3.1 4.1 7.3 0.1 2.9 3 0 0 3 3 3 0 NTPase MMR_HSR1 PF01926.23 KFL61892.1 - 0.34 11.0 1.2 34 4.5 0.4 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Fer4_7 PF12838.7 KFL61892.1 - 0.86 10.2 12.9 0.074 13.7 1.6 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KFL61892.1 - 1.9 8.8 9.9 0.25 11.5 1.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 KFL61892.1 - 8.3 6.9 11.6 1.4 9.4 2.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain ABC_tran PF00005.27 KFL61893.1 - 3.3e-34 118.4 0.0 1.4e-15 58.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFL61893.1 - 2.1e-11 43.7 2.7 0.0023 17.4 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFL61893.1 - 2.4e-09 37.4 6.6 0.25 11.1 2.0 4.5 3 2 2 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KFL61893.1 - 1.1e-06 28.7 0.0 0.037 14.0 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA PF00004.29 KFL61893.1 - 1.2e-05 25.7 0.1 0.017 15.5 0.1 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KFL61893.1 - 1.8e-05 24.6 0.3 0.18 11.5 0.0 3.0 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KFL61893.1 - 3e-05 24.3 0.0 0.0073 16.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain RLI PF04068.15 KFL61893.1 - 6.2e-05 22.7 4.4 6.2e-05 22.7 4.4 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 KFL61893.1 - 7e-05 22.5 2.5 7e-05 22.5 2.5 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.6 KFL61893.1 - 8.3e-05 23.0 0.0 0.027 14.9 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KFL61893.1 - 0.0002 20.9 0.8 0.0029 17.2 0.2 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KFL61893.1 - 0.0003 21.1 0.0 0.21 12.0 0.0 2.9 3 0 0 3 3 2 1 RNA helicase RsgA_GTPase PF03193.16 KFL61893.1 - 0.00038 20.4 0.2 0.78 9.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KFL61893.1 - 0.00083 19.9 0.1 1.6 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFL61893.1 - 0.00096 18.8 0.6 0.76 9.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KFL61893.1 - 0.0014 18.4 2.1 0.097 12.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KFL61893.1 - 0.002 17.8 2.9 0.053 13.1 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_21 PF14697.6 KFL61893.1 - 0.0021 18.1 8.6 0.0043 17.2 8.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain NB-ARC PF00931.22 KFL61893.1 - 0.0037 16.5 1.7 1.3 8.2 0.0 3.4 3 1 1 4 4 4 1 NB-ARC domain TsaE PF02367.17 KFL61893.1 - 0.0038 17.2 0.1 0.072 13.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFL61893.1 - 0.0041 17.1 2.1 0.26 11.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.17 KFL61893.1 - 0.0058 16.3 0.2 4 7.1 0.0 3.0 3 0 0 3 3 3 1 Thymidylate kinase Fer4_6 PF12837.7 KFL61893.1 - 0.0075 16.3 2.2 0.0075 16.3 2.2 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_23 PF13476.6 KFL61893.1 - 0.0078 16.7 1.5 0.43 11.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFL61893.1 - 0.0086 16.2 0.1 1.7 8.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFL61893.1 - 0.0096 15.7 0.4 0.54 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFL61893.1 - 0.018 15.0 0.1 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_10 PF13237.6 KFL61893.1 - 0.02 15.0 1.5 0.02 15.0 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_28 PF13521.6 KFL61893.1 - 0.021 15.1 0.1 3.7 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 KFL61893.1 - 0.028 14.6 8.9 0.059 13.5 8.9 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_13 PF13166.6 KFL61893.1 - 0.041 12.5 0.6 0.058 12.0 0.0 1.5 2 0 0 2 2 1 0 AAA domain TniB PF05621.11 KFL61893.1 - 0.044 13.2 0.1 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein VirE PF05272.11 KFL61893.1 - 0.048 13.4 0.0 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_16 PF13484.6 KFL61893.1 - 0.071 14.1 0.2 0.071 14.1 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain DnaB_C PF03796.15 KFL61893.1 - 0.08 12.3 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Fer4_17 PF13534.6 KFL61893.1 - 0.11 13.0 0.2 0.11 13.0 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain ATPase PF06745.13 KFL61893.1 - 0.15 11.3 0.1 0.34 10.2 0.1 1.5 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.9 KFL61893.1 - 0.21 11.3 2.4 0.25 11.1 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KFL61893.1 - 0.25 11.2 3.1 4 7.3 0.1 2.9 3 0 0 3 3 3 0 NTPase Fer4_7 PF12838.7 KFL61893.1 - 0.3 11.7 9.3 0.079 13.6 1.5 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain MMR_HSR1 PF01926.23 KFL61893.1 - 0.31 11.1 1.2 33 4.6 0.4 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Fer4_8 PF13183.6 KFL61893.1 - 4 8.0 10.5 1.2 9.6 2.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KFL61893.1 - 8.1 6.8 8.7 0.24 11.6 1.2 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain ABC_tran PF00005.27 KFL61894.1 - 4.4e-24 85.5 0.0 1.6e-15 57.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFL61894.1 - 1.4e-10 41.0 1.0 0.0023 17.4 0.1 3.0 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFL61894.1 - 1e-06 28.8 0.4 1.3 8.7 0.0 3.6 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFL61894.1 - 0.0013 18.3 0.2 0.0026 17.3 0.2 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFL61894.1 - 0.0024 18.2 0.0 0.0066 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFL61894.1 - 0.006 17.0 0.1 0.016 15.7 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFL61894.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KFL61894.1 - 0.027 14.4 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KFL61894.1 - 0.028 14.0 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KFL61894.1 - 0.034 12.8 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFL61894.1 - 0.04 13.6 0.1 0.09 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFL61894.1 - 0.052 13.9 0.0 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KFL61894.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain DnaB_C PF03796.15 KFL61894.1 - 0.069 12.5 0.0 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PduV-EutP PF10662.9 KFL61894.1 - 0.077 12.7 0.2 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KFL61894.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 KFL61894.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_15 PF13175.6 KFL61894.1 - 0.15 11.7 0.4 0.98 9.1 0.2 2.1 1 1 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 KFL61894.1 - 0.17 11.2 0.1 0.31 10.3 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KFL61894.1 - 0.2 12.1 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFL61894.1 - 0.21 11.3 0.0 0.5 10.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFL61895.1 - 4.5e-16 59.6 0.0 1.1e-15 58.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFL61895.1 - 1.7e-06 27.7 0.2 0.0044 16.5 0.0 3.0 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFL61895.1 - 0.00051 19.9 0.2 1 9.1 0.0 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFL61895.1 - 0.001 18.6 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFL61895.1 - 0.002 18.4 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFL61895.1 - 0.0049 17.3 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFL61895.1 - 0.0083 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KFL61895.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KFL61895.1 - 0.025 14.2 0.1 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KFL61895.1 - 0.026 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFL61895.1 - 0.032 14.0 0.1 0.073 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFL61895.1 - 0.04 14.3 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KFL61895.1 - 0.051 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain PduV-EutP PF10662.9 KFL61895.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 KFL61895.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NACHT PF05729.12 KFL61895.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 KFL61895.1 - 0.11 12.2 0.4 0.71 9.5 0.2 2.0 1 1 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 KFL61895.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATPase PF06745.13 KFL61895.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KFL61895.1 - 0.16 12.5 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFL61895.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFL61896.1 - 4.5e-16 59.6 0.0 1.1e-15 58.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFL61896.1 - 1.7e-06 27.7 0.2 0.0044 16.5 0.0 3.0 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFL61896.1 - 0.00051 19.9 0.2 1 9.1 0.0 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFL61896.1 - 0.001 18.6 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFL61896.1 - 0.002 18.4 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFL61896.1 - 0.0049 17.3 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFL61896.1 - 0.0083 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KFL61896.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KFL61896.1 - 0.025 14.2 0.1 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KFL61896.1 - 0.026 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFL61896.1 - 0.032 14.0 0.1 0.073 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFL61896.1 - 0.04 14.3 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KFL61896.1 - 0.051 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain PduV-EutP PF10662.9 KFL61896.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 KFL61896.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NACHT PF05729.12 KFL61896.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 KFL61896.1 - 0.11 12.2 0.4 0.71 9.5 0.2 2.0 1 1 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 KFL61896.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATPase PF06745.13 KFL61896.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KFL61896.1 - 0.16 12.5 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFL61896.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFL61897.1 - 4.5e-16 59.6 0.0 1.1e-15 58.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFL61897.1 - 1.7e-06 27.7 0.2 0.0044 16.5 0.0 3.0 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFL61897.1 - 0.00051 19.9 0.2 1 9.1 0.0 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFL61897.1 - 0.001 18.6 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFL61897.1 - 0.002 18.4 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFL61897.1 - 0.0049 17.3 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFL61897.1 - 0.0083 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KFL61897.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KFL61897.1 - 0.025 14.2 0.1 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KFL61897.1 - 0.026 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFL61897.1 - 0.032 14.0 0.1 0.073 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFL61897.1 - 0.04 14.3 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KFL61897.1 - 0.051 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain PduV-EutP PF10662.9 KFL61897.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 KFL61897.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NACHT PF05729.12 KFL61897.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 KFL61897.1 - 0.11 12.2 0.4 0.71 9.5 0.2 2.0 1 1 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 KFL61897.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATPase PF06745.13 KFL61897.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KFL61897.1 - 0.16 12.5 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFL61897.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFL61898.1 - 4.5e-16 59.6 0.0 1.1e-15 58.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFL61898.1 - 1.7e-06 27.7 0.2 0.0044 16.5 0.0 3.0 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFL61898.1 - 0.00051 19.9 0.2 1 9.1 0.0 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFL61898.1 - 0.001 18.6 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFL61898.1 - 0.002 18.4 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFL61898.1 - 0.0049 17.3 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFL61898.1 - 0.0083 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KFL61898.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KFL61898.1 - 0.025 14.2 0.1 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KFL61898.1 - 0.026 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFL61898.1 - 0.032 14.0 0.1 0.073 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFL61898.1 - 0.04 14.3 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KFL61898.1 - 0.051 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain PduV-EutP PF10662.9 KFL61898.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 KFL61898.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NACHT PF05729.12 KFL61898.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 KFL61898.1 - 0.11 12.2 0.4 0.71 9.5 0.2 2.0 1 1 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 KFL61898.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATPase PF06745.13 KFL61898.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KFL61898.1 - 0.16 12.5 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFL61898.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFL61899.1 - 4.5e-16 59.6 0.0 1.1e-15 58.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFL61899.1 - 1.7e-06 27.7 0.2 0.0044 16.5 0.0 3.0 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFL61899.1 - 0.00051 19.9 0.2 1 9.1 0.0 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFL61899.1 - 0.001 18.6 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFL61899.1 - 0.002 18.4 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFL61899.1 - 0.0049 17.3 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFL61899.1 - 0.0083 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KFL61899.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KFL61899.1 - 0.025 14.2 0.1 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KFL61899.1 - 0.026 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFL61899.1 - 0.032 14.0 0.1 0.073 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFL61899.1 - 0.04 14.3 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KFL61899.1 - 0.051 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain PduV-EutP PF10662.9 KFL61899.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 KFL61899.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NACHT PF05729.12 KFL61899.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 KFL61899.1 - 0.11 12.2 0.4 0.71 9.5 0.2 2.0 1 1 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 KFL61899.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATPase PF06745.13 KFL61899.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KFL61899.1 - 0.16 12.5 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFL61899.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFL61900.1 - 2.5e-24 86.4 0.0 1.1e-15 58.3 0.0 2.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFL61900.1 - 6.5e-11 42.1 1.0 0.0017 17.9 0.1 3.0 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFL61900.1 - 4.6e-07 30.0 0.4 1 9.1 0.0 3.6 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFL61900.1 - 0.001 18.7 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFL61900.1 - 0.0017 18.6 0.0 0.0046 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFL61900.1 - 0.0045 17.4 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFL61900.1 - 0.0072 16.7 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KFL61900.1 - 0.021 14.9 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KFL61900.1 - 0.021 14.4 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KFL61900.1 - 0.025 13.2 0.0 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFL61900.1 - 0.036 13.8 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFL61900.1 - 0.037 14.4 0.0 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KFL61900.1 - 0.039 13.9 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain DnaB_C PF03796.15 KFL61900.1 - 0.044 13.1 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PduV-EutP PF10662.9 KFL61900.1 - 0.052 13.3 0.2 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 KFL61900.1 - 0.081 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KFL61900.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 KFL61900.1 - 0.096 12.4 0.4 0.74 9.5 0.1 2.1 1 1 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 KFL61900.1 - 0.13 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 KFL61900.1 - 0.15 11.8 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-CCCH_4 PF18044.1 KFL61903.1 - 0.76 9.7 10.3 0.31 10.9 2.1 2.8 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCHH PF10283.9 KFL61903.1 - 8.8 6.4 11.6 3.2 7.8 2.4 3.4 3 0 0 3 3 3 0 PBZ domain Pkinase PF00069.25 KFL61904.1 - 7.1e-05 22.3 0.0 9.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KFL61905.1 - 1.9e-13 50.4 0.0 2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61905.1 - 2e-07 30.6 0.0 2.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RasGEF PF00617.19 KFL61906.1 - 0.001 19.3 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF PF00617.19 KFL61907.1 - 3.3e-50 170.8 0.1 5.9e-50 169.9 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFL61907.1 - 6.6e-26 90.6 0.1 1.4e-25 89.5 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KFL61907.1 - 7.1e-13 48.0 0.1 1.3e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFL61907.1 - 7.2e-11 41.6 0.1 1.9e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFL61907.1 - 8.6e-11 41.5 0.1 1.9e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KFL61907.1 - 0.0076 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 WW domain RHH_1 PF01402.21 KFL61907.1 - 0.063 13.2 0.8 0.23 11.4 0.8 2.0 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family UPRTase PF14681.6 KFL61908.1 - 4.2e-58 196.2 0.0 4.6e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFL61908.1 - 4.8e-07 29.4 0.0 7.8e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain MTABC_N PF16185.5 KFL61910.1 - 0.015 14.8 0.8 0.025 14.1 0.8 1.4 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region Rhomboid PF01694.22 KFL61912.1 - 3.6e-33 114.7 7.9 3.6e-33 114.7 7.9 1.8 2 0 0 2 2 2 1 Rhomboid family EAR PF07897.11 KFL61912.1 - 0.25 11.0 0.2 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression DUF2177 PF09945.9 KFL61912.1 - 0.25 11.4 5.8 0.43 10.7 0.4 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2177) DUF4381 PF14316.6 KFL61912.1 - 4 7.7 5.9 0.85 9.9 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Rhomboid PF01694.22 KFL61913.1 - 3.3e-33 114.8 7.9 3.3e-33 114.8 7.9 1.8 2 0 0 2 2 2 1 Rhomboid family DUF2177 PF09945.9 KFL61913.1 - 0.18 11.9 5.6 0.41 10.7 0.4 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2177) EAR PF07897.11 KFL61913.1 - 0.23 11.1 0.2 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression DUF4381 PF14316.6 KFL61913.1 - 3.7 7.8 5.9 0.81 9.9 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) PLDc_2 PF13091.6 KFL61915.1 - 3.5e-15 56.0 0.1 3.1e-07 30.4 0.0 3.6 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 KFL61915.1 - 5e-14 51.8 0.6 1.5e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF883 PF05957.13 KFL61915.1 - 0.33 11.6 1.6 0.79 10.4 0.6 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) PLDc PF00614.22 KFL61916.1 - 4.7e-14 51.9 0.6 1.4e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KFL61916.1 - 2.9e-12 46.6 0.1 2.8e-07 30.5 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain DUF883 PF05957.13 KFL61916.1 - 0.34 11.5 1.6 0.71 10.5 0.6 2.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) PLDc PF00614.22 KFL61917.1 - 4.7e-14 51.9 0.6 1.4e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KFL61917.1 - 2.9e-12 46.6 0.1 2.8e-07 30.5 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain DUF883 PF05957.13 KFL61917.1 - 0.34 11.5 1.6 0.71 10.5 0.6 2.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) PLDc PF00614.22 KFL61918.1 - 4.7e-14 51.9 0.6 1.4e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KFL61918.1 - 2.9e-12 46.6 0.1 2.8e-07 30.5 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain DUF883 PF05957.13 KFL61918.1 - 0.34 11.5 1.6 0.71 10.5 0.6 2.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Glyco_hydro_47 PF01532.20 KFL61920.1 - 1.3e-87 294.6 0.0 1.7e-87 294.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Alg6_Alg8 PF03155.15 KFL61921.1 - 1.3e-84 285.0 10.5 1.4e-84 284.8 10.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family YqhR PF11085.8 KFL61921.1 - 1.1 9.2 8.4 1.3 8.9 6.6 1.9 1 1 1 2 2 2 0 Conserved membrane protein YqhR Alg6_Alg8 PF03155.15 KFL61922.1 - 1.1e-46 159.8 2.4 1.2e-46 159.7 2.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Arteri_nucleo PF01481.16 KFL61924.1 - 0.14 12.4 0.8 0.27 11.6 0.8 1.4 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein S-antigen PF05756.11 KFL61924.1 - 0.24 11.8 2.0 0.64 10.4 2.0 1.8 1 0 0 1 1 1 0 S-antigen protein PBP1_TM PF14812.6 KFL61924.1 - 1.2 9.5 6.7 2.3 8.7 6.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med3 PF11593.8 KFL61925.1 - 0.92 8.6 5.1 0.98 8.5 5.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal UPF0113_N PF17833.1 KFL61928.1 - 3.3e-25 88.5 0.0 4.2e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KFL61928.1 - 3e-11 43.4 0.0 4.9e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain Cullin_binding PF03556.15 KFL61929.1 - 2.3e-31 108.7 3.6 3.5e-31 108.1 3.6 1.3 1 0 0 1 1 1 1 Cullin binding Cullin_binding PF03556.15 KFL61930.1 - 1.7e-31 109.2 3.6 2.1e-31 108.9 3.6 1.1 1 0 0 1 1 1 1 Cullin binding Cullin_binding PF03556.15 KFL61931.1 - 1.7e-31 109.2 3.6 2.1e-31 108.9 3.6 1.1 1 0 0 1 1 1 1 Cullin binding Mpv17_PMP22 PF04117.12 KFL61932.1 - 1.8e-12 47.3 5.8 9.9e-12 44.9 0.7 2.6 3 0 0 3 3 3 2 Mpv17 / PMP22 family UPF0139 PF03669.13 KFL61932.1 - 0.024 14.5 0.3 0.084 12.7 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) CKAP2_C PF15297.6 KFL61932.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Mpv17_PMP22 PF04117.12 KFL61933.1 - 9.6e-13 48.2 5.4 9.2e-12 45.0 0.7 2.8 3 0 0 3 3 3 2 Mpv17 / PMP22 family UPF0139 PF03669.13 KFL61933.1 - 0.019 14.8 0.2 0.078 12.9 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) CKAP2_C PF15297.6 KFL61933.1 - 0.1 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF1614 PF07758.11 KFL61935.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) EnY2 PF10163.9 KFL61936.1 - 5.9e-07 29.8 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Transcription factor e(y)2 RA PF00788.23 KFL61937.1 - 4e-12 46.6 0.0 7e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RA PF00788.23 KFL61938.1 - 4e-12 46.6 0.0 7e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ras PF00071.22 KFL61940.1 - 7.3e-29 100.4 0.1 7.3e-29 100.4 0.1 1.4 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFL61940.1 - 3.2e-23 82.2 0.1 3.2e-23 82.2 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL61940.1 - 1.9e-06 27.4 0.0 3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFL61940.1 - 0.00066 19.1 0.1 0.00066 19.1 0.1 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region CrgA PF06781.12 KFL61940.1 - 0.04 14.0 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Cell division protein CrgA TFIIA PF03153.13 KFL61940.1 - 0.18 11.8 32.0 0.24 11.4 32.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAP PF07174.11 KFL61940.1 - 1.4 8.3 16.3 2.5 7.5 16.3 1.5 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF5336 PF17270.2 KFL61940.1 - 6.7 6.3 5.7 19 4.8 5.7 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Ras PF00071.22 KFL61941.1 - 7.1e-27 94.0 0.0 7.1e-27 94.0 0.0 1.5 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFL61941.1 - 2.8e-23 82.4 0.1 2.8e-23 82.4 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL61941.1 - 2e-06 27.4 0.1 3.5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFL61941.1 - 0.0011 18.4 0.1 0.0011 18.4 0.1 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region CrgA PF06781.12 KFL61941.1 - 0.036 14.1 0.1 0.09 12.8 0.1 1.6 1 0 0 1 1 1 0 Cell division protein CrgA G-alpha PF00503.20 KFL61941.1 - 0.063 12.4 1.9 0.71 9.0 0.1 2.3 1 1 0 2 2 2 0 G-protein alpha subunit TFIIA PF03153.13 KFL61941.1 - 0.15 12.0 32.0 0.2 11.6 32.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAP PF07174.11 KFL61941.1 - 1.1 8.6 16.1 1.9 7.8 16.1 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF5336 PF17270.2 KFL61941.1 - 5.9 6.5 5.7 17 5.0 5.7 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Ras PF00071.22 KFL61942.1 - 7.1e-27 94.0 0.0 7.1e-27 94.0 0.0 1.5 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFL61942.1 - 2.8e-23 82.4 0.1 2.8e-23 82.4 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL61942.1 - 2e-06 27.4 0.1 3.5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFL61942.1 - 0.0011 18.4 0.1 0.0011 18.4 0.1 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region CrgA PF06781.12 KFL61942.1 - 0.036 14.1 0.1 0.09 12.8 0.1 1.6 1 0 0 1 1 1 0 Cell division protein CrgA G-alpha PF00503.20 KFL61942.1 - 0.063 12.4 1.9 0.71 9.0 0.1 2.3 1 1 0 2 2 2 0 G-protein alpha subunit TFIIA PF03153.13 KFL61942.1 - 0.15 12.0 32.0 0.2 11.6 32.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAP PF07174.11 KFL61942.1 - 1.1 8.6 16.1 1.9 7.8 16.1 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF5336 PF17270.2 KFL61942.1 - 5.9 6.5 5.7 17 5.0 5.7 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5336) SMC_Nse1 PF07574.13 KFL61944.1 - 3.6e-68 229.3 0.3 4.3e-68 229.0 0.3 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex ANAPC2 PF08672.11 KFL61944.1 - 0.01 16.4 0.0 0.045 14.3 0.0 2.1 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 DUF5344 PF17279.2 KFL61944.1 - 0.12 13.0 0.1 0.23 12.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5344) DUF4836 PF16120.5 KFL61945.1 - 0.16 10.9 0.0 0.19 10.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4836) Pkinase PF00069.25 KFL61947.1 - 2.6e-05 23.7 0.0 3.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL61947.1 - 0.00037 19.9 0.0 0.03 13.6 0.0 2.2 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KFL61947.1 - 0.00046 19.6 0.1 0.00067 19.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFL61947.1 - 0.00046 19.8 0.6 0.002 17.8 0.1 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KFL61947.1 - 0.0019 18.2 0.1 0.0031 17.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFL61947.1 - 0.032 13.8 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KFL61947.1 - 0.11 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Glyco_hydro_65N PF03636.15 KFL61948.1 - 1.3e-18 67.4 0.0 1.9e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 KFL61948.1 - 1.2e-13 50.7 0.0 2.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 KFL61949.1 - 3.7e-05 23.5 0.1 0.00014 21.7 0.1 2.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Glyco_hydro_65m PF03632.15 KFL61949.1 - 0.00037 19.5 0.0 0.00054 18.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain DUF5346 PF17281.2 KFL61950.1 - 0.021 14.8 1.2 0.034 14.2 1.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5346) Amidohydro_1 PF01979.20 KFL61952.1 - 7.7e-61 206.3 0.0 9.3e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFL61952.1 - 6.4e-07 29.2 0.0 8.5e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family A_deaminase PF00962.22 KFL61952.1 - 8.7e-05 22.0 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase tRNA_int_end_N2 PF12928.7 KFL61952.1 - 0.035 14.3 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 tRNA-splicing endonuclease subunit sen54 N-term Toxin_29 PF08116.11 KFL61952.1 - 0.071 13.1 0.3 0.071 13.1 0.3 1.9 2 0 0 2 2 2 0 PhTx neurotoxin family Fungal_trans_2 PF11951.8 KFL61956.1 - 2.7e-26 92.3 0.2 3.3e-26 92.0 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIB PF00382.19 KFL61956.1 - 0.024 14.7 0.0 0.059 13.4 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Statherin PF03875.13 KFL61958.1 - 0.072 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Statherin FMN_dh PF01070.18 KFL61959.1 - 3.7e-66 223.5 0.1 4.4e-66 223.3 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KFL61959.1 - 9.1e-07 28.3 0.1 1.2e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KFL61959.1 - 1.3e-05 24.7 0.1 1.8e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFL61959.1 - 0.00011 21.3 1.7 0.00074 18.6 0.2 2.4 1 1 2 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KFL61959.1 - 0.01 15.3 0.5 1.1 8.6 0.1 2.2 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 KFL61959.1 - 0.1 11.9 0.0 12 5.1 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 KFL61959.1 - 0.22 10.6 0.1 3 7.0 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF561) Cyt-b5 PF00173.28 KFL61960.1 - 2.8e-21 75.5 0.0 4.4e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FMN_dh PF01070.18 KFL61960.1 - 1.4e-20 73.6 0.0 1.8e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PAF-AH_p_II PF03403.13 KFL61960.1 - 0.14 10.6 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Cyt-b5 PF00173.28 KFL61961.1 - 1.5e-21 76.3 0.0 2.3e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Synaptobrevin PF00957.21 KFL61962.1 - 7.1e-14 51.4 0.2 1.1e-13 50.8 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KFL61962.1 - 1.2e-11 44.4 0.0 2.3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Amidohydro_2 PF04909.14 KFL61962.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase Longin PF13774.6 KFL61963.1 - 1.2e-11 44.4 0.0 2.2e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KFL61963.1 - 1.2e-06 28.3 0.6 1.7e-06 27.7 0.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Amidohydro_2 PF04909.14 KFL61963.1 - 0.037 13.8 0.0 0.058 13.2 0.0 1.4 1 1 0 1 1 1 0 Amidohydrolase Synaptobrevin PF00957.21 KFL61964.1 - 5.9e-14 51.6 0.2 8.6e-14 51.1 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KFL61964.1 - 1e-11 44.7 0.0 1.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Amidohydro_2 PF04909.14 KFL61964.1 - 0.097 12.4 0.0 0.097 12.4 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase Longin PF13774.6 KFL61965.1 - 9e-12 44.9 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KFL61965.1 - 9.4e-07 28.5 0.6 1.4e-06 28.0 0.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Amidohydro_2 PF04909.14 KFL61965.1 - 0.11 12.2 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase Profilin PF00235.19 KFL61966.1 - 2.4e-29 102.2 0.0 2.9e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Profilin Got1 PF04178.12 KFL61967.1 - 2.4e-13 50.5 7.4 2.9e-13 50.2 7.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Got1 PF04178.12 KFL61968.1 - 2.4e-13 50.5 7.4 2.9e-13 50.2 7.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Spt5-NGN PF03439.13 KFL61969.1 - 3e-23 81.5 0.0 6.7e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KFL61969.1 - 1.4e-17 64.5 10.7 1.4e-17 64.5 10.7 3.8 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KFL61969.1 - 2.3e-11 43.2 14.5 0.0024 17.8 1.6 5.5 5 0 0 5 5 5 3 KOW motif DUF3912 PF13051.6 KFL61969.1 - 0.00019 21.6 7.6 0.0092 16.2 0.0 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3912) DUF1506 PF07405.11 KFL61969.1 - 0.13 12.4 0.2 0.73 10.0 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1506) Acyl-CoA_dh_1 PF00441.24 KFL61970.1 - 1.8e-41 141.8 0.3 2.4e-41 141.4 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFL61970.1 - 2.2e-21 75.9 0.1 3.6e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFL61970.1 - 3.4e-20 72.8 0.0 7e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFL61970.1 - 3.1e-09 37.2 0.0 5.1e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 KFL61970.1 - 0.16 12.5 0.0 0.67 10.5 0.0 2.0 2 0 0 2 2 2 0 C6 domain RPN2_C PF18004.1 KFL61971.1 - 6.7e-58 195.1 8.3 6.7e-58 195.1 8.3 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KFL61971.1 - 9.7e-33 110.9 25.0 7.1e-10 38.8 0.0 8.8 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFL61971.1 - 3.1e-22 78.8 0.5 6.1e-16 58.6 0.0 3.3 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KFL61971.1 - 7.3e-09 35.9 0.1 0.017 15.6 0.0 4.0 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KFL61971.1 - 3.4e-06 26.8 0.0 1.7 9.1 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KFL61971.1 - 0.0021 18.1 0.0 0.16 12.0 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KFL61971.1 - 0.0066 17.0 2.3 1 10.3 0.0 3.9 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat GCIP PF13324.6 KFL61971.1 - 0.087 12.4 4.4 0.17 11.4 4.4 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting FAM178 PF14816.6 KFL61971.1 - 0.41 9.6 1.8 0.83 8.6 1.8 1.4 1 0 0 1 1 1 0 Family of unknown function, FAM178 DUF913 PF06025.12 KFL61971.1 - 4.2 6.2 9.4 3.2 6.6 1.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 KFL61971.1 - 8.2 6.7 18.5 0.18 12.1 3.1 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Astro_capsid_p PF12226.8 KFL61971.1 - 9.5 5.3 8.9 20 4.2 8.9 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RPN2_C PF18004.1 KFL61972.1 - 7e-50 169.1 9.2 7e-50 169.1 9.2 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KFL61972.1 - 8.2e-33 111.2 25.0 6.9e-10 38.9 0.0 8.8 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFL61972.1 - 2.8e-22 78.9 0.4 5.9e-16 58.6 0.0 3.7 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KFL61972.1 - 6.8e-09 36.0 0.1 0.017 15.6 0.0 4.0 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KFL61972.1 - 2.6e-06 27.2 0.0 1.7 9.2 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KFL61972.1 - 0.0019 18.2 0.0 0.16 12.0 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KFL61972.1 - 0.0061 17.1 2.3 0.97 10.3 0.0 4.0 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat GCIP PF13324.6 KFL61972.1 - 0.071 12.7 4.1 0.14 11.7 4.1 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting FAM178 PF14816.6 KFL61972.1 - 0.39 9.6 1.8 0.81 8.6 1.8 1.4 1 0 0 1 1 1 0 Family of unknown function, FAM178 Vfa1 PF08432.10 KFL61972.1 - 8.3 6.7 18.5 0.18 12.1 3.1 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Astro_capsid_p PF12226.8 KFL61972.1 - 9.7 5.2 8.9 19 4.3 8.9 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RPN2_C PF18004.1 KFL61973.1 - 6.3e-58 195.2 8.3 6.3e-58 195.2 8.3 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KFL61973.1 - 7.1e-33 111.4 25.0 6.9e-10 38.9 0.0 8.9 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFL61973.1 - 2.7e-22 79.0 0.4 5.8e-16 58.7 0.0 3.3 2 1 1 3 3 2 2 HEAT repeats HEAT_EZ PF13513.6 KFL61973.1 - 6.4e-09 36.1 0.1 0.017 15.6 0.0 4.0 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KFL61973.1 - 3e-06 27.0 0.0 1.6 9.2 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KFL61973.1 - 0.0019 18.2 0.0 0.16 12.0 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KFL61973.1 - 0.006 17.2 2.3 0.96 10.3 0.0 4.0 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat GCIP PF13324.6 KFL61973.1 - 0.077 12.6 4.1 0.14 11.7 4.1 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting FAM178 PF14816.6 KFL61973.1 - 0.39 9.7 1.8 0.8 8.6 1.8 1.4 1 0 0 1 1 1 0 Family of unknown function, FAM178 DUF913 PF06025.12 KFL61973.1 - 3.2 6.7 9.1 2.7 6.9 1.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 KFL61973.1 - 7.5 6.8 18.5 0.18 12.1 3.1 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Astro_capsid_p PF12226.8 KFL61973.1 - 9 5.3 8.9 19 4.3 8.9 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein UBN_AB PF14075.6 KFL61973.1 - 10 5.8 11.4 0.039 13.7 1.2 2.0 2 0 0 2 2 2 0 Ubinuclein conserved middle domain RPN2_C PF18004.1 KFL61974.1 - 4.5e-58 195.7 8.3 4.5e-58 195.7 8.3 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KFL61974.1 - 5.7e-32 108.5 30.0 5.4e-10 39.2 0.0 8.7 9 0 0 9 9 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFL61974.1 - 1.3e-22 80.0 0.5 4.4e-16 59.0 0.0 3.4 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KFL61974.1 - 3.2e-09 37.1 0.1 0.013 16.0 0.0 4.1 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KFL61974.1 - 1.5e-06 28.0 0.0 1.3 9.5 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KFL61974.1 - 0.0015 18.6 0.0 0.12 12.4 0.0 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KFL61974.1 - 0.0028 18.2 2.3 0.75 10.6 0.0 4.1 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat GCIP PF13324.6 KFL61974.1 - 0.061 12.9 4.2 0.11 12.1 4.2 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Phage_TAC_12 PF12363.8 KFL61974.1 - 0.12 12.8 0.2 0.66 10.4 0.1 2.3 3 0 0 3 3 1 0 Phage tail assembly chaperone protein, TAC FAM178 PF14816.6 KFL61974.1 - 0.37 9.7 1.8 0.61 9.0 1.8 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 DUF913 PF06025.12 KFL61974.1 - 2.5 7.0 9.0 2.6 6.9 1.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 KFL61974.1 - 5.4 6.8 16.5 6.7 6.4 3.0 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2052 PF09747.9 KFL61974.1 - 7 6.7 17.4 2.8 8.0 6.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PLDc_3 PF13918.6 KFL61975.1 - 0.088 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 PLD-like domain TMIE PF16038.5 KFL61975.1 - 8.8 6.3 7.2 11 6.0 2.7 2.3 1 1 1 2 2 2 0 TMIE protein Aldedh PF00171.22 KFL61980.1 - 5e-159 529.7 2.7 5.6e-159 529.5 2.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFL61980.1 - 0.0015 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) PLA2_B PF01735.18 KFL61983.1 - 3.3e-195 649.2 0.6 3.9e-195 648.9 0.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.18 KFL61984.1 - 7.3e-95 318.2 0.5 8.3e-95 318.0 0.5 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DAHP_synth_2 PF01474.16 KFL61985.1 - 9.5e-152 505.5 0.0 1.2e-151 505.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Sugar_tr PF00083.24 KFL61987.1 - 1e-82 278.4 9.2 1.2e-82 278.2 9.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFL61987.1 - 5.4e-12 45.3 27.1 1.4e-07 30.8 1.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KFL61989.1 - 5.6e-36 124.3 0.0 6.4e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Subtilosin_A PF11420.8 KFL61990.1 - 0.0056 16.6 0.2 0.014 15.3 0.2 1.6 1 0 0 1 1 1 1 Bacteriocin subtilosin A Myosin_head PF00063.21 KFL61992.1 - 5.2e-241 801.6 4.7 7e-241 801.2 4.7 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFL61992.1 - 3.6e-50 170.3 0.0 7.5e-50 169.2 0.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding OPA3 PF07047.12 KFL61992.1 - 2e-47 160.1 1.9 5.4e-47 158.7 1.9 1.8 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) SH3_1 PF00018.28 KFL61992.1 - 1.3e-11 43.9 0.0 2.6e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFL61992.1 - 3.4e-09 36.2 0.0 9.8e-09 34.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFL61992.1 - 5.4e-09 35.8 0.0 1.3e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 KFL61992.1 - 0.007 16.8 0.4 0.06 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFL61992.1 - 0.013 15.8 0.0 0.051 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain IQ PF00612.27 KFL61992.1 - 0.014 15.1 8.7 0.62 10.0 0.6 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif Med11 PF10280.9 KFL61992.1 - 0.022 15.2 2.2 0.13 12.7 0.9 2.6 2 0 0 2 2 2 0 Mediator complex protein Hpr_kinase_C PF07475.12 KFL61992.1 - 0.032 13.8 0.5 4.2 6.9 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Fungal_trans PF04082.18 KFL61994.1 - 0.0019 17.3 0.3 0.0053 15.8 0.3 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain PCP_red PF08369.10 KFL61994.1 - 0.0086 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Proto-chlorophyllide reductase 57 kD subunit PDH PF02153.17 KFL61994.1 - 0.071 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Orn_Arg_deC_N PF02784.16 KFL61995.1 - 5.9e-67 225.6 0.0 9.9e-67 224.9 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFL61995.1 - 6e-18 64.9 0.0 6.6e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 KFL61995.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel ATG22 PF11700.8 KFL61996.1 - 2.8e-46 158.1 8.6 3.1e-46 158.0 8.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KFL61996.1 - 9.9e-10 37.9 4.5 1.2e-09 37.6 4.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily SUIM_assoc PF16619.5 KFL61998.1 - 1.1 9.3 24.7 8.6 6.5 0.0 3.9 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SUIM_assoc PF16619.5 KFL61999.1 - 1.1 9.3 24.7 8.6 6.5 0.0 3.9 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Sel1 PF08238.12 KFL62000.1 - 1.4e-38 130.5 31.1 1.5e-05 25.5 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 KFL62000.1 - 0.021 15.4 5.4 2.8 8.8 0.3 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat Mitofilin PF09731.9 KFL62000.1 - 0.041 12.7 6.1 0.057 12.2 6.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FAM60A PF15396.6 KFL62000.1 - 5.2 7.0 8.5 3.4 7.6 3.9 2.3 2 0 0 2 2 2 0 Protein Family FAM60A PNISR PF15996.5 KFL62000.1 - 7.7 6.7 14.2 2.7 8.2 8.6 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Spt20 PF12090.8 KFL62000.1 - 9.1 5.8 26.1 5.5 6.5 19.0 2.2 2 0 0 2 2 2 0 Spt20 family Sel1 PF08238.12 KFL62001.1 - 1.3e-31 108.3 27.0 2.5e-05 24.8 1.9 6.4 6 0 0 6 6 6 6 Sel1 repeat TPR_6 PF13174.6 KFL62001.1 - 0.015 15.9 5.5 2.5 8.9 0.3 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat Mitofilin PF09731.9 KFL62001.1 - 0.029 13.2 5.8 0.04 12.8 5.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TPR_19 PF14559.6 KFL62001.1 - 1.2 9.7 7.6 5.2 7.7 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Spt20 PF12090.8 KFL62001.1 - 6.9 6.2 26.0 4.8 6.7 19.0 2.2 2 0 0 2 2 2 0 Spt20 family PNISR PF15996.5 KFL62001.1 - 8.4 6.6 14.5 3 8.1 9.0 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Apt1 PF10351.9 KFL62001.1 - 8.9 5.0 12.8 5.9 5.6 8.4 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain MFS_1 PF07690.16 KFL62002.1 - 7.2e-37 127.1 56.7 3.3e-35 121.6 56.7 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFL62002.1 - 6.9e-15 54.5 26.3 1.4e-14 53.4 26.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFL62002.1 - 1.1e-14 54.2 7.4 1.1e-14 54.2 7.4 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFL62002.1 - 0.072 11.4 10.3 0.32 9.2 4.1 2.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFL62003.1 - 9.4e-33 113.6 54.0 5.6e-31 107.8 54.3 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFL62003.1 - 1.1e-11 44.0 25.7 2.2e-11 42.9 25.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFL62003.1 - 2.2e-10 40.0 7.5 2.2e-10 40.0 7.5 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFL62003.1 - 0.013 13.8 8.3 0.08 11.2 2.3 2.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Sin3a_C PF16879.5 KFL62004.1 - 1.8e-77 260.9 0.1 1.8e-77 260.9 0.1 2.6 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KFL62004.1 - 2.3e-40 136.6 0.0 6.6e-40 135.1 0.0 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 KFL62004.1 - 5.2e-23 80.9 1.2 6.7e-17 61.4 1.4 2.9 2 0 0 2 2 2 2 Paired amphipathic helix repeat TSP_NTD PF17804.1 KFL62004.1 - 0.029 14.6 0.5 0.14 12.4 0.5 2.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Enkurin PF13864.6 KFL62004.1 - 0.61 10.6 3.7 0.88 10.0 0.0 3.2 3 0 0 3 3 3 0 Calmodulin-binding PAT1 PF09770.9 KFL62005.1 - 0.32 9.2 30.7 0.38 9.0 30.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Borrelia_P83 PF05262.11 KFL62005.1 - 1.4 7.3 15.4 1.8 7.0 15.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FAD_binding_2 PF00890.24 KFL62006.1 - 1e-81 275.2 0.4 1.3e-81 274.8 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KFL62006.1 - 3.7e-17 62.2 0.1 8.4e-16 57.9 0.0 2.9 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KFL62006.1 - 5.3e-12 46.0 0.6 1.2e-11 44.8 0.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFL62006.1 - 3e-10 40.0 1.2 1.2e-09 38.1 1.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFL62006.1 - 2.1e-08 34.3 1.3 7.7e-08 32.5 0.2 2.5 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFL62006.1 - 9.8e-08 31.6 0.4 1e-06 28.2 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFL62006.1 - 1.1e-06 28.2 0.0 0.0072 15.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFL62006.1 - 9.9e-06 24.5 4.1 0.00013 20.8 1.0 2.9 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KFL62006.1 - 9.3e-05 21.7 1.6 0.026 13.6 0.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KFL62006.1 - 0.00053 19.3 0.3 0.073 12.3 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KFL62006.1 - 0.00056 19.2 0.1 0.00094 18.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KFL62006.1 - 0.029 14.9 1.4 6 7.5 0.1 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFL62007.1 - 6e-82 276.0 0.4 6.9e-82 275.7 0.4 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFL62007.1 - 4.1e-12 46.4 0.8 9.9e-12 45.1 0.8 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFL62007.1 - 2.1e-10 40.6 1.2 8.4e-10 38.6 1.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFL62007.1 - 1.4e-08 34.9 1.3 5.9e-08 32.8 0.2 2.5 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFL62007.1 - 5.7e-08 32.3 0.5 7.1e-07 28.7 0.3 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFL62007.1 - 6.6e-07 28.9 0.0 0.0055 16.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFL62007.1 - 5.9e-06 25.2 4.4 0.0001 21.2 1.2 3.0 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KFL62007.1 - 6.5e-05 22.2 1.8 0.021 14.0 0.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KFL62007.1 - 0.00034 19.9 0.3 0.057 12.6 0.1 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KFL62007.1 - 0.00039 19.8 0.1 0.00065 19.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KFL62007.1 - 0.015 15.8 1.2 4.7 7.9 0.1 3.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFL62007.1 - 0.09 12.1 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KFL62008.1 - 1.8e-51 175.5 0.1 2.5e-51 175.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KFL62008.1 - 7.3e-21 74.1 0.1 6e-20 71.2 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain PP-binding PF00550.25 KFL62010.1 - 7.8e-15 55.0 0.1 1.5e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 KFL62010.1 - 1.3e-12 46.9 3.4 9.7e-06 25.1 0.3 5.1 4 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFL62010.1 - 4.8e-10 39.0 9.4 0.0039 16.9 0.1 4.4 3 1 1 4 4 4 4 Hexapeptide repeat of succinyl-transferase MMR_HSR1 PF01926.23 KFL62014.1 - 1.4e-09 38.0 2.3 1.6e-08 34.6 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KFL62014.1 - 1.8e-08 34.0 1.4 1.9e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Septin PF00735.18 KFL62014.1 - 0.00051 19.4 0.0 0.00051 19.4 0.0 2.3 2 1 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 KFL62014.1 - 0.00091 19.2 0.1 0.00091 19.2 0.1 2.2 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 KFL62014.1 - 0.00098 18.7 0.2 0.0024 17.4 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFL62014.1 - 0.0017 18.4 15.2 0.0084 16.2 0.0 3.9 2 2 2 4 4 3 2 Dynamin family Viral_helicase1 PF01443.18 KFL62014.1 - 0.0068 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KFL62014.1 - 0.013 15.8 0.0 0.013 15.8 0.0 2.4 2 2 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFL62014.1 - 0.015 14.5 0.3 0.044 13.0 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain SRPRB PF09439.10 KFL62014.1 - 0.022 14.2 0.0 0.022 14.2 0.0 2.4 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF4407 PF14362.6 KFL62014.1 - 0.023 14.0 12.3 0.039 13.3 12.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_tran PF00005.27 KFL62014.1 - 0.057 13.9 0.0 0.057 13.9 0.0 2.5 2 1 0 2 2 1 0 ABC transporter AAA_29 PF13555.6 KFL62014.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fzo_mitofusin PF04799.13 KFL62014.1 - 0.18 11.3 12.2 0.076 12.6 2.1 2.5 1 1 1 2 2 2 0 fzo-like conserved region FtsK_SpoIIIE PF01580.18 KFL62014.1 - 0.22 10.8 0.1 0.22 10.8 0.1 2.1 2 1 0 2 2 2 0 FtsK/SpoIIIE family SRP54 PF00448.22 KFL62014.1 - 0.71 9.5 4.7 10 5.7 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain FUSC PF04632.12 KFL62014.1 - 0.83 8.1 2.4 1.2 7.6 2.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 KFL62014.1 - 2.9 7.4 13.8 4.4 6.8 13.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit KfrA_N PF11740.8 KFL62014.1 - 5.4 7.7 16.9 0.39 11.4 10.6 2.2 1 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term GTP_EFTU PF00009.27 KFL62014.1 - 8.7 5.8 10.1 0.24 10.9 0.5 3.0 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFL62014.1 - 9.2 6.0 10.0 3.1 7.5 1.8 2.9 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein Cu-oxidase_2 PF07731.14 KFL62015.1 - 2.4e-36 124.5 0.1 4.3e-36 123.7 0.1 1.4 1 0 0 1 1 1 1 Multicopper oxidase LysM PF01476.20 KFL62018.1 - 1.9e-13 50.2 0.0 5.8e-05 23.1 0.0 3.2 3 0 0 3 3 3 2 LysM domain Sporozoite_P67 PF05642.11 KFL62018.1 - 0.53 8.3 10.0 0.78 7.8 10.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 KFL62018.1 - 3.4 7.7 27.6 6 6.8 27.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SOBP PF15279.6 KFL62019.1 - 1.3 9.6 10.5 1.8 9.1 10.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein GREB1 PF15782.5 KFL62019.1 - 3.4 4.7 10.0 3.9 4.4 10.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 KFL62019.1 - 3.4 6.1 8.5 4.6 5.7 8.5 1.2 1 0 0 1 1 1 0 Macoilin family MPDZ_u10 PF16667.5 KFL62019.1 - 7.9 7.5 9.4 0.46 11.4 2.2 2.6 2 1 2 4 4 4 0 Unstructured region 10 on multiple PDZ protein MTP18 PF10558.9 KFL62020.1 - 1.7e-69 233.2 0.1 3.3e-69 232.2 0.1 1.4 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Melibiase_2_C PF17450.2 KFL62021.1 - 0.17 12.1 0.0 0.99 9.7 0.0 1.9 1 1 1 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain APH PF01636.23 KFL62022.1 - 5.1e-07 29.9 0.1 9.1e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KFL62022.1 - 0.024 13.5 0.1 0.12 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 KFL62022.1 - 0.034 13.5 0.1 0.44 9.8 0.0 2.2 2 0 0 2 2 2 0 Ecdysteroid kinase Choline_kinase PF01633.20 KFL62022.1 - 0.066 12.8 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase SAC3_GANP PF03399.16 KFL62023.1 - 3e-20 72.8 2.8 2.5e-09 36.9 0.2 2.2 1 1 1 2 2 2 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KFL62023.1 - 0.038 14.0 0.5 0.092 12.7 0.1 1.9 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family Chitin_synth_1 PF01644.17 KFL62025.1 - 1.3e-77 259.3 0.0 1.8e-77 258.9 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KFL62025.1 - 6.4e-29 99.7 0.1 1.7e-28 98.4 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFL62025.1 - 1.7e-21 76.5 0.0 3.3e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KFL62025.1 - 2.3e-06 27.6 0.1 3.7e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KFL62025.1 - 0.0084 16.0 0.0 0.031 14.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Pkinase PF00069.25 KFL62029.1 - 0.069 12.5 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Aquarius_N PF16399.5 KFL62031.1 - 1.2e-292 972.9 0.0 1.4e-292 972.6 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KFL62031.1 - 2.1e-25 89.5 0.0 3.9e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFL62031.1 - 1.8e-22 80.4 0.0 3.5e-22 79.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFL62031.1 - 3e-07 30.4 0.0 0.00013 21.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFL62031.1 - 2e-06 28.2 0.0 4.2e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KFL62031.1 - 6.7e-06 26.2 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KFL62031.1 - 0.00071 20.0 0.2 0.0035 17.7 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KFL62031.1 - 0.001 19.5 0.0 0.0046 17.4 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KFL62031.1 - 0.0015 18.3 0.1 0.3 10.8 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 KFL62031.1 - 0.0042 16.4 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain PIF1 PF05970.14 KFL62031.1 - 0.0086 15.3 0.0 0.89 8.7 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.21 KFL62031.1 - 0.013 15.0 0.0 0.034 13.7 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KFL62031.1 - 0.014 15.7 1.6 0.57 10.5 0.1 2.8 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 KFL62031.1 - 0.018 15.1 0.0 0.074 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 KFL62031.1 - 0.02 14.7 0.1 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase Adeno_IVa2 PF02456.15 KFL62031.1 - 0.041 12.7 0.0 0.097 11.5 0.0 1.6 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF2075 PF09848.9 KFL62031.1 - 0.068 12.4 1.0 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 KFL62031.1 - 0.076 12.9 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain SPOUT_MTase PF02590.17 KFL62031.1 - 0.086 12.8 0.0 4.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase ATPase_2 PF01637.18 KFL62031.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KFL62031.1 - 0.19 12.1 0.0 0.85 10.0 0.0 2.2 1 0 0 1 1 1 0 RNA helicase 3HCDH_N PF02737.18 KFL62032.1 - 4.5e-38 130.9 0.9 6.4e-38 130.4 0.9 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFL62032.1 - 2.9e-34 117.5 0.0 5.4e-34 116.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain FeoC PF09012.10 KFL62032.1 - 0.12 12.5 0.7 0.76 9.9 0.0 2.5 3 0 0 3 3 3 0 FeoC like transcriptional regulator PaaX PF07848.12 KFL62032.1 - 0.13 12.5 0.0 9.1 6.6 0.0 2.4 2 0 0 2 2 2 0 PaaX-like protein 3HCDH PF00725.22 KFL62033.1 - 2.5e-34 117.8 0.0 3.9e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.18 KFL62033.1 - 9.1e-33 113.6 0.4 1.2e-32 113.2 0.4 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PaaX PF07848.12 KFL62033.1 - 0.09 13.0 0.0 7.3 6.9 0.0 2.4 2 0 0 2 2 2 0 PaaX-like protein FeoC PF09012.10 KFL62033.1 - 0.21 11.7 0.2 0.62 10.2 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator Pribosyltran PF00156.27 KFL62035.1 - 4.1e-06 26.4 0.0 6.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.27 KFL62036.1 - 3.4e-06 26.6 0.0 6.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.27 KFL62037.1 - 0.00041 19.9 0.0 0.00059 19.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PTRF_SDPR PF15237.6 KFL62037.1 - 0.14 11.7 0.2 0.18 11.4 0.2 1.1 1 0 0 1 1 1 0 PTRF/SDPR family Pribosyltran PF00156.27 KFL62038.1 - 0.00033 20.2 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PTRF_SDPR PF15237.6 KFL62038.1 - 0.12 11.9 0.2 0.15 11.6 0.2 1.1 1 0 0 1 1 1 0 PTRF/SDPR family Pribosyltran PF00156.27 KFL62039.1 - 0.00027 20.5 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SSB PF00436.25 KFL62044.1 - 5.9e-14 52.0 0.0 7.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family SSB PF00436.25 KFL62045.1 - 9.6e-08 32.0 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family Ku_N PF03731.15 KFL62046.1 - 2e-29 102.9 0.0 2.9e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KFL62047.1 - 2e-28 98.9 5.3 3.6e-28 98.1 5.3 1.4 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm Ku PF02735.16 KFL62047.1 - 6.2e-22 78.3 0.2 3.7e-21 75.8 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain SAP PF02037.27 KFL62047.1 - 6.4e-14 51.3 0.0 1.1e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 KFL62047.1 - 0.00012 21.7 0.2 0.00024 20.7 0.2 1.5 1 0 0 1 1 1 1 HeH/LEM domain SAP30_Sin3_bdg PF13867.6 KFL62047.1 - 0.085 13.2 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Cyto_heme_lyase PF01265.17 KFL62048.1 - 1e-85 287.9 0.8 1.2e-85 287.7 0.8 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Nucleopor_Nup85 PF07575.13 KFL62050.1 - 3.1e-21 75.6 0.0 3e-16 59.1 0.0 2.3 2 0 0 2 2 2 2 Nup85 Nucleoporin Nucleopor_Nup85 PF07575.13 KFL62051.1 - 4.2e-16 58.6 0.0 5.7e-11 41.7 0.0 2.4 2 1 0 2 2 2 2 Nup85 Nucleoporin TPR_19 PF14559.6 KFL62052.1 - 1.4e-10 41.5 2.9 0.00063 20.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFL62052.1 - 3.1e-09 36.3 11.5 0.046 13.8 0.4 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFL62052.1 - 3.3e-08 33.4 1.7 0.53 10.8 0.0 5.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFL62052.1 - 1.6e-07 31.8 6.2 0.00011 22.7 0.3 4.1 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFL62052.1 - 7.8e-07 29.4 2.1 0.45 11.5 0.0 4.8 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFL62052.1 - 9.3e-07 28.9 1.4 0.0011 19.1 0.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFL62052.1 - 1e-05 25.1 2.2 0.8 9.4 0.0 4.3 3 1 1 4 4 4 2 TPR repeat ANAPC3 PF12895.7 KFL62052.1 - 8e-05 22.8 0.7 0.0069 16.6 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFL62052.1 - 0.00037 20.7 6.5 0.65 10.3 0.4 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFL62052.1 - 0.00053 20.0 10.2 0.14 12.5 0.6 4.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFL62052.1 - 0.00089 19.0 14.6 0.43 10.5 1.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.17 KFL62052.1 - 0.0028 18.1 1.2 0.024 15.1 0.4 2.2 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 KFL62052.1 - 0.0099 15.7 2.9 0.14 12.0 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFL62052.1 - 0.013 15.9 0.1 0.62 10.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 KFL62052.1 - 0.023 13.9 0.2 4.4 6.4 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.10 KFL62052.1 - 0.025 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 KFL62052.1 - 0.048 14.3 5.6 3.5 8.5 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFL62052.1 - 0.057 12.8 0.5 1.6 8.1 0.2 2.1 2 0 0 2 2 2 0 MalT-like TPR region TPR_7 PF13176.6 KFL62052.1 - 0.073 13.1 4.6 23 5.3 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFL62052.1 - 0.31 11.8 0.2 0.31 11.8 0.2 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFL62053.1 - 3.9e-05 23.2 0.1 9.4e-05 22.0 0.1 1.7 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 KFL62053.1 - 0.053 13.4 0.1 1.1 9.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFL62053.1 - 0.13 13.1 0.0 0.6 11.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Metallophos PF00149.28 KFL62056.1 - 2.1e-40 139.4 0.1 2.7e-40 139.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFL62056.1 - 1.1e-22 80.2 2.6 1.4e-22 79.9 1.7 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 KFL62057.1 - 2.1e-40 139.4 0.1 2.7e-40 139.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFL62057.1 - 1.1e-22 80.2 2.6 1.4e-22 79.9 1.7 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Arf PF00025.21 KFL62058.1 - 6.5e-64 214.6 0.0 7.3e-64 214.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFL62058.1 - 2.6e-09 36.7 0.0 1.1e-05 24.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFL62058.1 - 2.5e-08 33.6 0.0 3.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFL62058.1 - 2.7e-06 27.4 0.0 3.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KFL62058.1 - 6.3e-06 26.4 0.0 1.4e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFL62058.1 - 0.00022 20.8 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFL62058.1 - 0.0025 17.2 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region mRNA_decap_C PF16741.5 KFL62058.1 - 0.094 12.0 0.2 0.65 9.3 0.1 2.1 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus Vezatin PF12632.7 KFL62060.1 - 1e-71 241.6 0.3 2.1e-71 240.6 0.3 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes PCNA_N PF00705.18 KFL62060.1 - 1.5e-52 176.6 4.0 3.6e-52 175.4 4.0 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KFL62060.1 - 1.4e-50 170.7 0.0 6.2e-50 168.7 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KFL62060.1 - 4.7e-05 23.0 0.0 7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Rad9 MatE PF01554.18 KFL62060.1 - 0.0035 17.0 0.3 1.9 8.1 1.9 2.3 1 1 1 2 2 2 2 MatE TetR_C_9 PF14514.6 KFL62060.1 - 0.0064 16.6 0.2 0.015 15.4 0.2 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Wzy_C PF04932.15 KFL62060.1 - 0.067 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 O-Antigen ligase Polysacc_synt_C PF14667.6 KFL62060.1 - 0.18 11.9 6.3 0.34 11.0 6.3 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Dynein_light PF01221.18 KFL62063.1 - 7.2e-40 135.2 2.6 8.2e-40 135.0 2.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF1805 PF08827.11 KFL62063.1 - 0.038 14.3 0.3 0.049 14.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) RhoGEF67_u1 PF16615.5 KFL62063.1 - 0.21 12.1 0.1 0.33 11.5 0.1 1.2 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 PCI PF01399.27 KFL62065.1 - 8.3e-10 39.1 0.0 1.5e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.14 KFL62065.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF433) PCI PF01399.27 KFL62066.1 - 7.5e-10 39.3 0.0 1.3e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.14 KFL62066.1 - 0.092 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Peptidase_M24 PF00557.24 KFL62068.1 - 5.5e-49 166.7 0.0 6.6e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KFL62068.1 - 1.6e-19 69.9 5.3 3.1e-19 69.0 5.3 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KFL62068.1 - 0.002 18.2 6.0 0.002 18.2 6.0 2.2 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 KFL62068.1 - 1.7 8.6 4.8 4 7.4 4.8 1.7 1 0 0 1 1 1 0 HIT zinc finger Peptidase_M24 PF00557.24 KFL62069.1 - 2.4e-47 161.3 0.0 2.9e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Iso_dh PF00180.20 KFL62073.1 - 3.5e-79 266.5 0.2 8e-79 265.3 0.2 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ICMT PF04140.14 KFL62073.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PK PF00224.21 KFL62074.1 - 6.8e-174 577.7 4.5 8.2e-174 577.4 4.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFL62074.1 - 1.5e-18 67.1 1.8 5.1e-18 65.4 1.2 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KFL62074.1 - 0.00014 21.1 0.4 0.00043 19.5 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KFL62074.1 - 0.0032 16.5 0.1 0.038 13.0 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain PK PF00224.21 KFL62075.1 - 4.2e-174 578.4 4.5 4.9e-174 578.1 4.5 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.14 KFL62075.1 - 8.9e-05 21.7 0.2 0.00034 19.8 0.1 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KFL62075.1 - 0.0021 17.1 0.1 0.031 13.3 0.0 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain PK_C PF02887.16 KFL62075.1 - 0.0086 16.3 2.2 0.031 14.5 1.5 2.3 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain PK PF00224.21 KFL62076.1 - 1.1e-125 419.2 4.0 1.5e-125 418.7 4.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFL62076.1 - 1.1e-38 132.0 0.0 3e-38 130.6 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KFL62076.1 - 8.2e-05 21.8 0.2 0.0003 20.0 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DUF218 PF02698.17 KFL62076.1 - 0.089 12.8 0.0 0.26 11.3 0.0 1.9 1 1 0 1 1 1 0 DUF218 domain PK PF00224.21 KFL62077.1 - 5.7e-126 420.1 4.6 7.2e-126 419.7 4.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFL62077.1 - 1.1e-38 132.1 0.0 3e-38 130.7 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KFL62077.1 - 8.1e-05 21.9 0.2 0.0003 20.0 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DUF218 PF02698.17 KFL62077.1 - 0.089 12.8 0.0 0.27 11.3 0.0 1.9 1 1 0 1 1 1 0 DUF218 domain SUR7 PF06687.12 KFL62079.1 - 9.9e-31 107.0 0.1 1.3e-30 106.7 0.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Ribosomal_S17_N PF16205.5 KFL62080.1 - 8.6e-33 112.5 0.4 1.7e-32 111.6 0.4 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KFL62080.1 - 1.2e-24 86.2 0.4 6.1e-24 83.9 0.5 2.1 2 0 0 2 2 2 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 KFL62081.1 - 1.3e-17 63.9 0.1 2.8e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Pap_E4 PF02711.14 KFL62081.1 - 7.5 7.6 6.9 3.8 8.5 3.3 2.0 2 0 0 2 2 2 0 E4 protein Metallophos PF00149.28 KFL62082.1 - 1.5e-37 130.1 0.1 2.2e-37 129.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFL62082.1 - 3.5e-15 56.2 0.0 6.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 KFL62083.1 - 1.3e-37 130.3 0.1 1.8e-37 129.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFL62083.1 - 3.2e-15 56.3 0.0 5.4e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain HIRA_B PF09453.10 KFL62084.1 - 0.00042 20.1 0.5 0.0013 18.5 0.5 1.9 1 0 0 1 1 1 1 HIRA B motif ANAPC4_WD40 PF12894.7 KFL62084.1 - 0.00046 20.4 0.0 0.54 10.6 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFL62084.1 - 0.0012 19.6 3.5 0.61 11.1 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Transglut_core PF01841.19 KFL62085.1 - 9e-14 51.9 0.4 1.7e-13 51.0 0.4 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 KFL62085.1 - 2.8e-05 23.8 0.2 5.5e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Cyclin_N PF00134.23 KFL62087.1 - 8.9e-36 122.4 0.1 8.9e-36 122.4 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFL62087.1 - 2.3e-09 37.4 1.5 1.6e-08 34.7 0.1 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain TMPIT PF07851.13 KFL62087.1 - 0.066 12.5 0.0 0.092 12.0 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Cyclin_N PF00134.23 KFL62088.1 - 8.9e-36 122.4 0.1 8.9e-36 122.4 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFL62088.1 - 2.3e-09 37.4 1.5 1.6e-08 34.7 0.1 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain TMPIT PF07851.13 KFL62088.1 - 0.066 12.5 0.0 0.092 12.0 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein NAPRTase PF04095.16 KFL62090.1 - 7.3e-57 192.7 0.0 2.3e-28 99.4 0.2 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KFL62090.1 - 1.8e-35 122.0 0.1 3.5e-35 121.1 0.1 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 KFL62091.1 - 2.6e-57 194.2 0.0 1.3e-28 100.2 0.2 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KFL62091.1 - 0.00073 19.9 0.1 0.0017 18.8 0.1 1.7 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Mpv17_PMP22 PF04117.12 KFL62093.1 - 2.3e-21 75.8 0.3 3.8e-21 75.1 0.3 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 KFL62094.1 - 7.3e-18 64.6 1.3 2.8e-16 59.5 0.2 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 KFL62095.1 - 1.1e-21 76.8 0.3 1.8e-21 76.1 0.3 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 KFL62096.1 - 1.1e-21 76.8 0.3 1.8e-21 76.1 0.3 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Kinesin PF00225.23 KFL62097.1 - 1.3e-83 280.7 0.1 1.5e-83 280.5 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFL62097.1 - 2.5e-26 92.4 0.0 4.3e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 KFL62097.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KFL62097.1 - 0.21 11.0 0.9 0.99 8.8 0.1 2.2 3 0 0 3 3 3 0 PhoH-like protein TetR_C_24 PF17932.1 KFL62098.1 - 0.063 13.6 4.1 2.9 8.2 0.4 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF948 PF06103.11 KFL62098.1 - 0.14 12.4 10.3 0.63 10.3 0.1 3.6 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 KFL62098.1 - 0.91 9.6 0.0 0.91 9.6 0.0 3.6 2 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Microtub_bind PF13931.6 KFL62099.1 - 6.4e-08 33.1 1.2 6.4e-08 33.1 1.2 3.4 2 1 1 3 3 3 1 Kinesin-associated microtubule-binding LPP PF04728.13 KFL62099.1 - 0.13 12.7 7.4 0.16 12.4 0.3 3.6 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DUF2570 PF10828.8 KFL62099.1 - 0.2 11.5 11.4 0.13 12.1 6.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) V-SNARE_C PF12352.8 KFL62099.1 - 0.27 11.5 3.6 2.2 8.6 0.2 3.4 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus LMBR1 PF04791.16 KFL62099.1 - 0.4 9.5 10.8 0.59 9.0 10.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Focal_AT PF03623.13 KFL62099.1 - 0.68 9.9 10.8 0.068 13.2 0.8 3.4 2 1 2 4 4 4 0 Focal adhesion targeting region COG2 PF06148.11 KFL62099.1 - 0.97 9.5 9.3 0.14 12.2 2.1 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 KFL62099.1 - 1.9 7.6 17.1 0.32 10.2 1.4 2.6 2 1 1 3 3 3 0 TMPIT-like protein Tht1 PF04163.12 KFL62099.1 - 3.1 6.5 8.1 3.1 6.5 7.3 1.3 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein Apolipoprotein PF01442.18 KFL62099.1 - 5.7 6.8 27.1 3.3 7.6 12.9 2.8 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain CENP-K PF11802.8 KFL62099.1 - 7.5 6.0 22.4 0.94 9.0 18.5 1.4 2 0 0 2 2 2 0 Centromere-associated protein K T2SSF PF00482.23 KFL62100.1 - 0.11 12.4 0.1 0.33 10.9 0.2 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F zf-ANAPC11 PF12861.7 KFL62101.1 - 7.2e-26 90.1 1.8 9.1e-26 89.8 1.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFL62101.1 - 4e-06 27.0 1.0 6.5e-06 26.3 1.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain RPEL PF02755.15 KFL62103.1 - 2.4e-18 65.2 1.4 2.9e-08 33.2 0.1 2.5 2 0 0 2 2 2 2 RPEL repeat SQS_PSY PF00494.19 KFL62104.1 - 1.2e-34 120.1 0.0 2.1e-34 119.3 0.0 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase Amidohydro_2 PF04909.14 KFL62105.1 - 4e-07 30.1 0.0 4.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase DnaJ-X PF14308.6 KFL62106.1 - 4.1e-75 251.8 4.2 4.1e-75 251.8 4.2 2.9 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 KFL62106.1 - 3.6e-25 87.8 0.3 8.9e-25 86.6 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain Condensin2nSMC PF12422.8 KFL62106.1 - 0.077 13.2 0.2 0.26 11.4 0.1 2.0 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit WHIM1 PF15612.6 KFL62106.1 - 0.16 11.6 0.1 0.5 10.0 0.1 1.9 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 OrfB_IS605 PF01385.19 KFL62106.1 - 0.22 11.7 2.2 0.56 10.4 2.2 1.6 1 0 0 1 1 1 0 Probable transposase DnaJ-X PF14308.6 KFL62107.1 - 1e-79 266.9 5.7 1e-79 266.9 5.7 2.5 2 1 0 2 2 2 1 X-domain of DnaJ-containing Condensin2nSMC PF12422.8 KFL62107.1 - 0.079 13.1 0.1 0.079 13.1 0.1 2.1 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit WHIM1 PF15612.6 KFL62107.1 - 0.15 11.6 0.1 0.44 10.2 0.1 1.9 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 OrfB_IS605 PF01385.19 KFL62107.1 - 0.18 12.0 2.2 0.48 10.7 2.2 1.7 1 0 0 1 1 1 0 Probable transposase DnaJ-X PF14308.6 KFL62108.1 - 1e-79 266.9 5.7 1e-79 266.9 5.7 2.5 2 1 0 2 2 2 1 X-domain of DnaJ-containing Condensin2nSMC PF12422.8 KFL62108.1 - 0.079 13.1 0.1 0.079 13.1 0.1 2.1 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit WHIM1 PF15612.6 KFL62108.1 - 0.15 11.6 0.1 0.44 10.2 0.1 1.9 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 OrfB_IS605 PF01385.19 KFL62108.1 - 0.18 12.0 2.2 0.48 10.7 2.2 1.7 1 0 0 1 1 1 0 Probable transposase DnaJ-X PF14308.6 KFL62109.1 - 1e-79 266.9 5.7 1e-79 266.9 5.7 2.5 2 1 0 2 2 2 1 X-domain of DnaJ-containing Condensin2nSMC PF12422.8 KFL62109.1 - 0.079 13.1 0.1 0.079 13.1 0.1 2.1 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit WHIM1 PF15612.6 KFL62109.1 - 0.15 11.6 0.1 0.44 10.2 0.1 1.9 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 OrfB_IS605 PF01385.19 KFL62109.1 - 0.18 12.0 2.2 0.48 10.7 2.2 1.7 1 0 0 1 1 1 0 Probable transposase DnaJ-X PF14308.6 KFL62110.1 - 1e-79 266.9 5.7 1e-79 266.9 5.7 2.5 2 1 0 2 2 2 1 X-domain of DnaJ-containing Condensin2nSMC PF12422.8 KFL62110.1 - 0.079 13.1 0.1 0.079 13.1 0.1 2.1 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit WHIM1 PF15612.6 KFL62110.1 - 0.15 11.6 0.1 0.44 10.2 0.1 1.9 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 OrfB_IS605 PF01385.19 KFL62110.1 - 0.18 12.0 2.2 0.48 10.7 2.2 1.7 1 0 0 1 1 1 0 Probable transposase DnaJ-X PF14308.6 KFL62111.1 - 2.3e-75 252.7 4.2 2.3e-75 252.7 4.2 2.5 2 1 0 2 2 2 1 X-domain of DnaJ-containing WHIM1 PF15612.6 KFL62111.1 - 0.13 11.8 0.1 0.38 10.4 0.1 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 OrfB_IS605 PF01385.19 KFL62111.1 - 0.16 12.2 2.2 0.39 10.9 2.2 1.6 1 0 0 1 1 1 0 Probable transposase Condensin2nSMC PF12422.8 KFL62111.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.1 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit DnaJ-X PF14308.6 KFL62112.1 - 2.3e-75 252.7 4.2 2.3e-75 252.7 4.2 2.5 2 1 0 2 2 2 1 X-domain of DnaJ-containing WHIM1 PF15612.6 KFL62112.1 - 0.13 11.8 0.1 0.38 10.4 0.1 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 OrfB_IS605 PF01385.19 KFL62112.1 - 0.16 12.2 2.2 0.39 10.9 2.2 1.6 1 0 0 1 1 1 0 Probable transposase Condensin2nSMC PF12422.8 KFL62112.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.1 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit Sugar_tr PF00083.24 KFL62113.1 - 5.1e-12 45.4 7.8 5.1e-12 45.4 7.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF4396 PF14342.6 KFL62113.1 - 0.31 11.4 5.2 0.44 10.9 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) Pkinase PF00069.25 KFL62114.1 - 2.7e-11 43.3 0.0 1.1e-09 38.1 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62114.1 - 4.6e-10 39.2 0.0 5.9e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase ALIX_LYPXL_bnd PF13949.6 KFL62115.1 - 5.1e-81 272.2 15.4 9.7e-81 271.3 15.4 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV BRO1 PF03097.18 KFL62115.1 - 1.1e-66 225.2 0.5 1.1e-66 225.2 0.5 2.1 2 1 0 2 2 2 1 BRO1-like domain DUF416 PF04222.12 KFL62115.1 - 0.17 11.3 7.0 1 8.8 0.1 3.5 4 1 1 5 5 5 0 Protein of unknown function (DUF416) DUF2383 PF09537.10 KFL62115.1 - 1.5 9.2 9.0 1.2 9.5 0.6 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF2383) Baculo_PEP_C PF04513.12 KFL62115.1 - 8.3 6.4 7.8 0.51 10.4 0.8 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Adipogenin PF15202.6 KFL62116.1 - 0.24 11.4 0.9 0.37 10.8 0.9 1.3 1 0 0 1 1 1 0 Adipogenin EF-hand_7 PF13499.6 KFL62118.1 - 4.6e-13 49.4 0.0 1e-08 35.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KFL62118.1 - 2.9e-11 43.5 0.0 8e-05 22.9 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_6 PF13405.6 KFL62118.1 - 5.1e-10 38.5 0.2 0.011 15.6 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KFL62118.1 - 6.9e-10 37.8 0.0 0.019 14.5 0.0 4.1 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFL62118.1 - 8.8e-07 28.7 0.1 4.2e-05 23.3 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 KFL62118.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) EF-hand_14 PF17959.1 KFL62118.1 - 0.11 12.9 0.0 12 6.3 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_9 PF14658.6 KFL62119.1 - 6.7e-08 32.7 0.0 7.7e-05 23.0 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_6 PF13405.6 KFL62119.1 - 1.3e-06 27.9 0.1 0.014 15.3 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KFL62119.1 - 1.5e-06 27.3 0.0 0.071 12.7 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFL62119.1 - 2.9e-05 24.4 0.0 0.19 12.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 KFL62120.1 - 3.6e-13 49.8 0.2 9.1e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KFL62120.1 - 4.8e-11 42.8 0.0 3.7e-05 23.9 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KFL62120.1 - 4.3e-10 38.7 0.1 0.01 15.7 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KFL62120.1 - 1.2e-09 37.0 0.0 0.017 14.6 0.0 3.7 3 1 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFL62120.1 - 1e-06 28.4 0.1 3.7e-05 23.5 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 KFL62120.1 - 0.093 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) EF-hand_14 PF17959.1 KFL62120.1 - 0.097 13.0 0.0 11 6.5 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_9 PF14658.6 KFL62121.1 - 4.8e-08 33.2 0.0 6.6e-05 23.2 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_6 PF13405.6 KFL62121.1 - 1e-06 28.2 0.1 0.012 15.5 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KFL62121.1 - 1.2e-06 27.7 0.0 0.062 12.9 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFL62121.1 - 2.3e-05 24.8 0.0 0.16 12.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 KFL62122.1 - 2.6e-13 50.2 0.2 7.5e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KFL62122.1 - 3.4e-11 43.3 0.0 3.1e-05 24.2 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KFL62122.1 - 3e-10 39.2 0.1 0.0089 15.9 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KFL62122.1 - 8.2e-10 37.5 0.0 0.015 14.8 0.0 3.7 3 1 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFL62122.1 - 7.5e-07 28.9 0.1 3.1e-05 23.7 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_14 PF17959.1 KFL62122.1 - 0.074 13.4 0.0 8.9 6.7 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain DUF3216 PF11505.8 KFL62122.1 - 0.081 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Xpo1 PF08389.12 KFL62123.1 - 0.0012 18.9 0.1 0.031 14.3 0.0 3.1 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 KFL62123.1 - 0.0045 17.3 0.0 0.023 15.1 0.0 2.2 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 KFL62123.1 - 0.016 15.7 0.0 0.19 12.3 0.0 2.9 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.22 KFL62123.1 - 0.028 14.7 0.0 19 5.9 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat GAT PF03127.14 KFL62123.1 - 0.031 14.6 0.0 2 8.8 0.0 2.7 2 0 0 2 2 2 0 GAT domain Xpo1 PF08389.12 KFL62124.1 - 0.0012 18.9 0.1 0.031 14.3 0.0 3.1 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 KFL62124.1 - 0.0045 17.3 0.0 0.023 15.1 0.0 2.2 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 KFL62124.1 - 0.016 15.7 0.0 0.19 12.3 0.0 2.9 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.22 KFL62124.1 - 0.028 14.7 0.0 19 5.9 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat GAT PF03127.14 KFL62124.1 - 0.031 14.6 0.0 2 8.8 0.0 2.7 2 0 0 2 2 2 0 GAT domain Xpo1 PF08389.12 KFL62125.1 - 0.0011 19.1 0.1 0.029 14.4 0.0 3.1 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 KFL62125.1 - 0.0039 17.5 0.0 0.022 15.2 0.0 2.3 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 KFL62125.1 - 0.015 15.8 0.0 0.18 12.3 0.0 3.0 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.22 KFL62125.1 - 0.024 14.9 0.0 18 5.9 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat GAT PF03127.14 KFL62125.1 - 0.029 14.7 0.0 1.9 8.8 0.0 2.6 2 0 0 2 2 2 0 GAT domain Xpo1 PF08389.12 KFL62126.1 - 0.00088 19.4 0.1 0.023 14.7 0.0 3.0 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 KFL62126.1 - 0.004 17.5 0.0 0.016 15.6 0.0 2.0 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 KFL62126.1 - 0.011 16.2 0.0 0.14 12.7 0.0 2.9 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.22 KFL62126.1 - 0.012 15.8 0.0 14 6.2 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat GAT PF03127.14 KFL62126.1 - 0.02 15.2 0.0 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 GAT domain 3HCDH_RFF PF18321.1 KFL62127.1 - 0.31 11.5 3.3 0.64 10.5 2.8 1.6 1 1 1 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain LSM PF01423.22 KFL62128.1 - 2.8e-13 49.3 0.2 3.4e-13 49.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFL62128.1 - 0.001 18.7 0.1 0.0016 18.0 0.1 1.3 1 0 0 1 1 1 1 Hfq protein 5-FTHF_cyc-lig PF01812.20 KFL62129.1 - 2.9e-21 76.2 0.0 7.2e-21 74.9 0.0 1.6 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family BAR_2 PF10455.9 KFL62130.1 - 1.9e-61 207.7 0.2 2.9e-61 207.1 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KFL62130.1 - 2.8e-20 73.0 5.7 6.3e-19 68.6 5.7 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KFL62130.1 - 0.0092 15.7 0.4 0.18 11.5 0.0 2.3 2 0 0 2 2 2 1 BAR domain of APPL family ApoLp-III PF07464.11 KFL62130.1 - 0.014 15.5 2.8 0.47 10.5 0.1 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TetR_C_24 PF17932.1 KFL62130.1 - 0.051 13.9 0.1 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SRP_TPR_like PF17004.5 KFL62130.1 - 0.085 12.9 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Putative TPR-like repeat TACC_C PF05010.14 KFL62130.1 - 0.11 12.3 2.2 4 7.2 0.2 2.4 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SPATA19 PF15212.6 KFL62130.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial BAR_2 PF10455.9 KFL62131.1 - 9.3e-55 185.8 0.2 1.4e-54 185.2 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KFL62131.1 - 1.6e-12 47.6 6.5 3.9e-11 43.1 6.5 2.0 1 1 0 1 1 1 1 BAR domain ApoLp-III PF07464.11 KFL62131.1 - 0.013 15.6 2.8 0.43 10.7 0.1 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TetR_C_24 PF17932.1 KFL62131.1 - 0.061 13.6 0.1 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SPATA19 PF15212.6 KFL62131.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial GAS PF13851.6 KFL62131.1 - 0.15 11.4 2.6 9.1 5.6 0.0 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TACC_C PF05010.14 KFL62131.1 - 0.27 11.0 3.3 3.8 7.2 0.2 2.4 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF5594 PF18057.1 KFL62132.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5594) Ribonuc_red_sm PF00268.21 KFL62140.1 - 7e-122 406.2 2.0 8.4e-122 406.0 2.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.21 KFL62141.1 - 1.1e-116 389.2 2.3 1.4e-116 388.9 2.3 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.21 KFL62142.1 - 1.1e-116 389.2 2.3 1.4e-116 388.9 2.3 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NUDIX PF00293.28 KFL62143.1 - 5.9e-17 61.9 0.1 1.1e-16 61.1 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain eIF-5_eIF-2B PF01873.17 KFL62147.1 - 4.5e-24 84.6 0.0 8.8e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF2894 PF11445.8 KFL62147.1 - 0.33 11.4 5.6 7.2 7.0 5.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) Vfa1 PF08432.10 KFL62147.1 - 0.36 11.2 7.6 0.51 10.6 7.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 eIF-5_eIF-2B PF01873.17 KFL62148.1 - 4.3e-41 139.5 0.1 7.3e-41 138.7 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zf-HYPF PF07503.12 KFL62148.1 - 0.2 11.5 2.8 9 6.2 0.0 2.8 3 0 0 3 3 3 0 HypF finger eIF-5_eIF-2B PF01873.17 KFL62149.1 - 3.8e-24 84.8 0.0 7.2e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Vfa1 PF08432.10 KFL62149.1 - 0.25 11.6 7.4 0.35 11.2 7.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2894 PF11445.8 KFL62149.1 - 0.57 10.6 5.5 13 6.2 5.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) AIM24 PF01987.17 KFL62150.1 - 4e-54 183.5 0.4 4.7e-54 183.2 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 ADH_zinc_N PF00107.26 KFL62152.1 - 2.1e-23 82.7 0.1 4.3e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFL62152.1 - 2.6e-21 75.5 1.4 9.9e-21 73.7 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KFL62152.1 - 4.5e-07 29.6 0.1 1.2e-06 28.2 0.1 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KFL62152.1 - 0.00047 21.2 0.0 0.0012 19.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFL62152.1 - 0.0019 17.5 0.3 0.0032 16.8 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KFL62152.1 - 0.0043 16.7 0.0 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FtsJ PF01728.19 KFL62152.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Pyr_redox_2 PF07992.14 KFL62152.1 - 0.026 13.8 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 KFL62152.1 - 0.029 15.1 0.0 0.052 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HI0933_like PF03486.14 KFL62152.1 - 0.052 12.2 0.2 0.076 11.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein PrmA PF06325.13 KFL62152.1 - 0.063 12.7 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFL62152.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Arteri_nsp7a PF16749.5 KFL62152.1 - 0.12 12.5 0.1 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha FAD_binding_4 PF01565.23 KFL62154.1 - 1.8e-35 121.7 0.0 3.1e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KFL62154.1 - 4.3e-33 115.0 0.0 8.1e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Coatomer_WDAD PF04053.14 KFL62155.1 - 1.9e-141 472.2 0.1 2.8e-141 471.6 0.1 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KFL62155.1 - 3.6e-108 361.9 0.0 5.6e-108 361.3 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KFL62155.1 - 4.2e-33 112.8 22.2 1.7e-07 31.8 0.3 8.0 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL62155.1 - 2.4e-07 31.0 0.1 0.022 15.1 0.0 5.1 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KFL62155.1 - 0.0028 17.5 0.1 0.34 10.8 0.0 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS Nup160 PF11715.8 KFL62155.1 - 0.021 13.5 6.2 1.6 7.3 0.4 3.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 KFL62156.1 - 1.8e-141 472.3 0.1 2.3e-141 471.9 0.1 1.1 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KFL62156.1 - 6.2e-103 344.7 0.6 6.9e-102 341.2 0.6 2.0 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KFL62156.1 - 2.1e-17 63.1 10.7 2.9e-05 24.7 0.2 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL62156.1 - 0.00016 21.9 0.1 0.019 15.2 0.0 3.8 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KFL62156.1 - 0.0022 17.8 0.1 0.3 10.9 0.0 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS Nup160 PF11715.8 KFL62156.1 - 0.0034 16.1 0.1 1.6 7.3 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 KFL62157.1 - 1.7e-141 472.3 0.1 2.2e-141 471.9 0.1 1.1 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KFL62157.1 - 2.9e-108 362.2 0.0 4.6e-108 361.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KFL62157.1 - 2e-17 63.3 10.7 2.9e-05 24.7 0.2 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL62157.1 - 0.00015 22.0 0.1 0.019 15.3 0.0 3.8 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KFL62157.1 - 0.0021 17.9 0.1 0.3 11.0 0.0 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS Nup160 PF11715.8 KFL62157.1 - 0.0033 16.1 0.1 1.6 7.3 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 KFL62158.1 - 1.2e-141 472.8 0.1 1.6e-141 472.4 0.1 1.1 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KFL62158.1 - 3.4e-103 345.5 0.4 4.2e-102 341.9 0.4 2.0 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Clathrin PF00637.20 KFL62158.1 - 0.0013 18.6 0.1 0.25 11.2 0.0 3.0 3 0 0 3 3 3 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 KFL62159.1 - 1.2e-141 472.8 0.1 1.5e-141 472.5 0.1 1.1 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KFL62159.1 - 2.1e-108 362.7 0.0 3e-108 362.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Clathrin PF00637.20 KFL62159.1 - 0.0012 18.7 0.1 0.24 11.3 0.0 3.0 3 0 0 3 3 3 2 Region in Clathrin and VPS RRM_1 PF00076.22 KFL62161.1 - 2.6e-29 100.9 0.0 6.7e-17 61.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFB6 PF17110.5 KFL62161.1 - 2.2e-22 79.6 0.0 3.3e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH RRM_3 PF08777.11 KFL62161.1 - 0.00025 21.1 0.0 0.0011 19.0 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KFL62161.1 - 0.00025 21.0 0.0 0.0014 18.6 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFL62161.1 - 0.0079 16.3 0.0 0.046 13.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 KFL62161.1 - 0.015 14.9 0.0 0.055 13.1 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFL62161.1 - 0.018 14.9 0.0 0.051 13.4 0.0 1.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif Statherin PF03875.13 KFL62161.1 - 0.59 10.3 6.8 1.9 8.6 6.8 1.9 1 0 0 1 1 1 0 Statherin TRAPP PF04051.16 KFL62164.1 - 4.8e-28 97.7 0.0 5.4e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KFL62164.1 - 0.0022 16.9 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF810 PF05664.11 KFL62165.1 - 2.5e-06 26.4 0.2 4.6e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) Sec6 PF06046.13 KFL62165.1 - 0.0018 16.7 1.6 0.003 16.0 1.6 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 NDUF_B8 PF05821.11 KFL62166.1 - 2.4e-06 27.5 0.0 2.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) UnbV_ASPIC PF07593.12 KFL62167.1 - 0.01 15.8 0.1 0.094 12.7 0.1 2.4 2 1 0 2 2 2 0 ASPIC and UnbV ATP12 PF07542.11 KFL62168.1 - 1.1e-39 135.5 0.2 1.4e-39 135.1 0.2 1.1 1 0 0 1 1 1 1 ATP12 chaperone protein Iso_dh PF00180.20 KFL62170.1 - 6.7e-41 140.6 0.0 9e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PH PF00169.29 KFL62172.1 - 0.16 12.5 0.2 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 PH domain RNA_pol_Rpb6 PF01192.22 KFL62173.1 - 5.7e-17 61.4 0.1 8.1e-17 60.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 MFS_1 PF07690.16 KFL62174.1 - 1.3e-16 60.5 41.7 1.3e-11 44.0 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 KFL62175.1 - 9e-12 45.3 0.0 1e-11 45.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFL62175.1 - 2.1e-09 37.4 0.0 3.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFL62175.1 - 5.8e-06 26.6 0.0 7.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFL62175.1 - 8.2e-06 25.7 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFL62175.1 - 0.00028 21.0 0.1 0.00035 20.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PCI PF01399.27 KFL62176.1 - 3e-12 47.0 0.6 1.4e-10 41.6 0.0 3.1 2 0 0 2 2 2 1 PCI domain BAH PF01426.18 KFL62176.1 - 0.0019 18.0 0.1 0.0064 16.3 0.1 2.0 1 1 0 1 1 1 1 BAH domain Pro_Al_protease PF02983.14 KFL62176.1 - 0.049 13.7 0.0 0.34 11.0 0.0 2.5 1 0 0 1 1 1 0 Alpha-lytic protease prodomain PCI PF01399.27 KFL62177.1 - 2.9e-12 47.0 0.6 1.3e-10 41.7 0.0 3.1 2 0 0 2 2 2 1 PCI domain BAH PF01426.18 KFL62177.1 - 0.0019 18.0 0.0 0.006 16.4 0.0 1.9 1 1 0 1 1 1 1 BAH domain Pro_Al_protease PF02983.14 KFL62177.1 - 0.046 13.8 0.0 0.33 11.0 0.0 2.6 1 0 0 1 1 1 0 Alpha-lytic protease prodomain PCI PF01399.27 KFL62178.1 - 2.8e-12 47.1 0.5 1.3e-10 41.7 0.0 3.0 2 0 0 2 2 2 1 PCI domain BAH PF01426.18 KFL62178.1 - 0.0018 18.1 0.0 0.0056 16.5 0.0 1.9 1 1 0 1 1 1 1 BAH domain Pro_Al_protease PF02983.14 KFL62178.1 - 0.042 13.9 0.0 0.32 11.1 0.0 2.6 1 0 0 1 1 1 0 Alpha-lytic protease prodomain PDEase_I PF00233.19 KFL62180.1 - 1.5e-63 214.7 0.0 2.2e-63 214.2 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_L10 PF00466.20 KFL62180.1 - 2.9e-23 81.9 0.0 5.6e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 KFL62180.1 - 1.2e-05 25.2 0.0 2.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P DnaJ_C PF01556.18 KFL62181.1 - 3.3e-39 134.3 0.0 4.1e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KFL62181.1 - 6.5e-15 55.2 18.6 1.1e-14 54.5 18.6 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KFL62181.1 - 0.77 9.8 10.2 1.2 9.2 2.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DnaJ_C PF01556.18 KFL62182.1 - 2.7e-26 92.4 0.0 3.8e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFL62182.1 - 7.1e-25 86.9 2.5 1.2e-24 86.2 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFL62182.1 - 6.7e-15 55.2 18.6 1.1e-14 54.6 18.6 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KFL62182.1 - 0.73 9.9 10.2 1.1 9.3 2.3 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4727 PF15856.5 KFL62183.1 - 0.0035 17.0 0.0 0.004 16.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4727) MFS_1 PF07690.16 KFL62184.1 - 9.2e-22 77.4 11.4 1.1e-21 77.2 11.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL62184.1 - 8.5e-08 31.5 0.9 1e-07 31.2 0.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KFL62184.1 - 0.00039 19.1 6.3 0.00049 18.8 6.3 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.13 KFL62184.1 - 0.00092 17.7 0.3 0.0011 17.5 0.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5392 PF17370.2 KFL62185.1 - 0.2 11.7 0.6 0.62 10.2 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5392) CLTH PF10607.9 KFL62186.1 - 4e-29 101.4 0.0 7.7e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KFL62186.1 - 2.2e-24 85.9 0.2 3.7e-24 85.1 0.2 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KFL62186.1 - 0.0035 17.3 0.5 0.0088 16.0 0.1 1.9 2 0 0 2 2 2 1 LisH IDO PF01231.18 KFL62187.1 - 9.5e-25 87.3 0.0 1.5e-24 86.6 0.0 1.2 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase BIR PF00653.21 KFL62188.1 - 0.34 11.6 3.7 2.9 8.6 0.0 2.1 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain zf_UBZ PF18439.1 KFL62188.1 - 1.1 8.9 3.4 8.1 6.1 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger dUTPase PF00692.19 KFL62189.1 - 2.5e-37 127.4 0.0 3.5e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase dUTPase PF00692.19 KFL62190.1 - 7.5e-28 96.8 0.0 9.8e-28 96.4 0.0 1.2 1 0 0 1 1 1 1 dUTPase Phos_pyr_kin PF08543.12 KFL62191.1 - 2.2e-11 43.6 0.0 3.8e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KFL62191.1 - 3.4e-07 29.9 0.1 9.1e-07 28.5 0.0 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KFL62192.1 - 2.1e-08 33.8 0.0 3.7e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KFL62192.1 - 4.6e-07 29.4 0.4 1.1e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 pfkB family carbohydrate kinase PQ-loop PF04193.14 KFL62194.1 - 2.1e-29 101.0 16.8 9e-18 63.8 1.3 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF3429 PF11911.8 KFL62194.1 - 0.013 15.8 3.0 0.021 15.1 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) ERGIC_N PF13850.6 KFL62194.1 - 0.1 13.0 0.6 0.78 10.1 0.0 2.6 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SPATA9 PF15824.5 KFL62194.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 ATP-synt_DE_N PF02823.16 KFL62195.1 - 2.1e-15 56.4 0.0 3.3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE_N PF02823.16 KFL62196.1 - 1.5e-15 56.9 0.0 2.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE_N PF02823.16 KFL62197.1 - 1.5e-15 56.9 0.0 2.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE_N PF02823.16 KFL62198.1 - 2e-11 43.6 0.1 3.1e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ABC_tran PF00005.27 KFL62200.1 - 6.8e-31 107.6 0.0 1.1e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFL62200.1 - 4.8e-08 32.7 0.3 0.00017 21.1 0.1 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFL62200.1 - 0.00036 20.4 1.0 0.16 11.8 0.7 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 KFL62200.1 - 0.0013 18.4 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_24 PF13479.6 KFL62200.1 - 0.0017 18.1 0.0 0.0061 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFL62200.1 - 0.0058 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 KFL62200.1 - 0.007 16.5 0.3 0.015 15.4 0.3 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain MeaB PF03308.16 KFL62200.1 - 0.0077 15.2 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KFL62200.1 - 0.01 15.9 0.1 0.034 14.2 0.1 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KFL62200.1 - 0.014 15.8 0.3 0.031 14.7 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KFL62200.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFL62200.1 - 0.15 12.3 1.0 1.4 9.2 1.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFL62200.1 - 0.2 11.7 0.8 12 5.9 0.2 3.0 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Glyco_transf_41 PF13844.6 KFL62201.1 - 7.2e-103 344.5 0.2 1.9e-52 178.3 0.0 3.2 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_2 PF07719.17 KFL62201.1 - 3.5e-06 26.7 3.5 0.024 14.7 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFL62201.1 - 3.5e-06 26.8 2.7 0.02 15.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFL62201.1 - 1.5e-05 24.6 4.9 0.0051 16.6 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFL62201.1 - 1.7e-05 24.4 10.6 0.001 18.7 0.3 3.9 2 1 2 4 4 4 2 TPR repeat TPR_17 PF13431.6 KFL62201.1 - 6.6e-05 23.0 4.2 1.8 9.1 0.0 4.4 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFL62201.1 - 9.4e-05 22.9 0.2 0.022 15.5 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFL62201.1 - 0.0003 21.4 3.3 0.12 13.1 0.3 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFL62201.1 - 0.00037 20.3 4.3 0.25 11.3 0.7 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFL62201.1 - 0.00058 19.7 0.8 0.38 10.9 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFL62201.1 - 0.0015 18.8 1.0 1.6 9.0 0.1 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFL62201.1 - 0.0034 17.9 1.2 0.048 14.2 0.3 2.8 2 1 2 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 KFL62201.1 - 0.026 15.0 0.1 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_2 PF07719.17 KFL62202.1 - 9.7e-09 34.7 0.4 0.0013 18.7 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFL62202.1 - 1.2e-07 31.3 0.1 0.003 17.2 0.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.28 KFL62202.1 - 2.3e-07 30.3 0.1 0.0028 17.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFL62202.1 - 0.00016 21.9 0.1 0.00034 20.8 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFL62202.1 - 0.0024 18.1 2.1 1.6 9.1 0.9 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFL62202.1 - 0.011 15.6 3.2 0.24 11.3 0.8 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFL62202.1 - 0.015 15.8 0.3 0.043 14.3 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFL62202.1 - 0.015 15.9 0.3 0.046 14.4 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFL62202.1 - 0.039 14.2 0.3 7.3 7.1 0.0 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFL62202.1 - 0.32 11.9 1.2 10 7.2 1.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Sec23_trunk PF04811.15 KFL62203.1 - 6e-78 261.8 0.0 8.7e-78 261.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KFL62203.1 - 7.8e-29 100.3 0.0 1.6e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KFL62203.1 - 4.5e-25 87.5 0.2 1.4e-24 85.9 0.2 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KFL62203.1 - 4.2e-11 42.6 0.0 1.1e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KFL62203.1 - 3.9e-07 30.0 0.2 7.9e-07 29.0 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 KFL62203.1 - 0.094 12.1 0.8 0.19 11.1 0.3 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Sec23_trunk PF04811.15 KFL62204.1 - 5.5e-78 261.9 0.0 7.9e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KFL62204.1 - 7.3e-29 100.4 0.0 1.5e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KFL62204.1 - 4.6e-25 87.4 0.2 1.3e-24 86.0 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KFL62204.1 - 1.2e-13 50.9 1.0 2.3e-13 49.9 1.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFL62204.1 - 3.9e-11 42.7 0.0 1.1e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KFL62204.1 - 0.093 12.1 0.8 0.2 11.1 0.3 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Topoisom_I PF01028.20 KFL62207.1 - 7.9e-99 329.6 2.6 7.9e-99 329.6 2.6 2.1 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KFL62207.1 - 1.1e-71 240.8 2.3 1.1e-71 240.8 2.3 2.7 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KFL62207.1 - 4.1e-33 113.1 1.0 2e-32 110.9 1.0 2.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain Topoisom_I PF01028.20 KFL62208.1 - 5.8e-97 323.5 1.5 1e-96 322.7 1.5 1.3 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KFL62208.1 - 5.3e-72 241.8 2.3 5.3e-72 241.8 2.3 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Vps8 PF12816.7 KFL62209.1 - 5.6e-65 218.6 0.1 5.6e-65 218.6 0.1 2.5 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KFL62209.1 - 1.5e-07 31.3 6.9 0.0053 16.6 0.1 4.1 5 1 0 5 5 5 2 Region in Clathrin and VPS Pox_D3 PF04580.13 KFL62209.1 - 0.013 15.2 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-C3H2C3 PF17122.5 KFL62209.1 - 0.13 12.3 0.1 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger WD40 PF00400.32 KFL62209.1 - 0.15 13.0 1.2 0.4 11.6 0.1 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-RING_2 PF13639.6 KFL62209.1 - 0.75 10.2 2.0 1.3 9.4 0.1 2.4 3 0 0 3 3 3 0 Ring finger domain TBCC PF07986.12 KFL62210.1 - 4.1e-10 39.4 0.0 5.8e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KFL62211.1 - 1.7e-13 51.0 0.1 2.2e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain F_actin_bind PF08919.10 KFL62211.1 - 0.033 14.3 0.3 3.1 7.9 0.0 2.2 1 1 1 2 2 2 0 F-actin binding RTX PF02382.15 KFL62211.1 - 0.091 12.4 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein CactinC_cactus PF09732.9 KFL62213.1 - 1.2e-57 193.3 6.2 1.5e-57 192.9 6.2 1.1 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 KFL62213.1 - 0.028 14.8 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Cactin_mid PF10312.9 KFL62214.1 - 4.6e-35 121.2 0.6 5.9e-35 120.8 0.6 1.1 1 0 0 1 1 1 1 Conserved mid region of cactin CTP_synth_N PF06418.14 KFL62216.1 - 2e-66 224.0 0.0 2.6e-66 223.6 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KFL62216.1 - 7.1e-56 189.0 0.0 1.1e-55 188.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFL62216.1 - 6.2e-06 26.1 0.5 6.9e-05 22.7 0.5 2.3 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 KFL62217.1 - 6.2e-56 189.2 0.0 8.6e-56 188.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CTP_synth_N PF06418.14 KFL62217.1 - 8.2e-44 149.9 0.0 1.2e-43 149.4 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus Peptidase_C26 PF07722.13 KFL62217.1 - 4.1e-06 26.7 0.8 5.8e-05 23.0 0.4 2.6 2 1 0 2 2 2 1 Peptidase C26 Mab-21 PF03281.14 KFL62221.1 - 0.24 10.7 0.0 0.28 10.4 0.0 1.0 1 0 0 1 1 1 0 Mab-21 protein HA2 PF04408.23 KFL62223.1 - 2.7e-21 75.9 0.0 6e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFL62223.1 - 2.6e-15 56.7 0.0 6.5e-15 55.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFL62223.1 - 1.3e-14 54.4 0.0 6.4e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFL62223.1 - 0.052 13.3 0.1 0.094 12.5 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mito_carr PF00153.27 KFL62224.1 - 1.2e-73 243.1 0.3 3.6e-25 87.7 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KFL62224.1 - 3.5e-11 43.4 3.4 4.1e-09 36.8 0.7 3.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KFL62224.1 - 7.7e-11 41.0 5.5 5.9e-07 28.9 0.1 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KFL62224.1 - 2.2e-08 33.1 9.9 7.2e-07 28.3 0.1 4.5 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.6 KFL62224.1 - 2.4e-06 26.7 2.4 4.9e-05 22.6 0.1 3.2 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFL62224.1 - 0.00081 19.2 0.5 2.2 8.2 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain pair Mito_carr PF00153.27 KFL62225.1 - 3e-42 142.4 0.1 2.8e-25 88.1 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein EF-hand_7 PF13499.6 KFL62225.1 - 7.2e-14 52.0 7.1 3.2e-09 37.1 0.7 3.7 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 KFL62225.1 - 6.1e-12 44.4 7.8 4.8e-07 29.2 0.1 5.7 7 0 0 7 7 7 2 EF-hand domain EF-hand_1 PF00036.32 KFL62225.1 - 2.2e-11 42.5 10.8 5.9e-07 28.6 0.1 5.8 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 KFL62225.1 - 1.1e-06 28.3 2.4 1.5 8.8 0.0 5.0 5 1 1 6 6 6 3 EF-hand domain pair EF-hand_5 PF13202.6 KFL62225.1 - 4.1e-05 22.9 0.1 4.1e-05 22.9 0.1 3.7 5 0 0 5 5 5 1 EF hand EF-hand_9 PF14658.6 KFL62225.1 - 0.035 14.4 0.0 16 5.9 0.0 3.5 3 0 0 3 3 3 0 EF-hand domain SSrecog PF03531.14 KFL62234.1 - 2.4e-30 104.2 0.0 3.2e-29 100.7 0.0 2.7 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 KFL62234.1 - 5.1e-30 103.8 0.4 1.1e-28 99.5 0.1 2.6 3 0 0 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 KFL62234.1 - 9.6e-26 90.0 0.1 4.7e-25 87.8 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 KFL62235.1 - 1.9e-30 104.6 0.0 2.7e-29 100.9 0.0 2.7 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 KFL62235.1 - 2.9e-29 101.3 0.2 9.3e-29 99.7 0.1 1.9 2 0 0 2 2 2 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 KFL62235.1 - 2.1e-19 69.7 0.0 1.2e-18 67.3 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 KFL62236.1 - 1.9e-30 104.6 0.0 2.7e-29 100.9 0.0 2.7 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 KFL62236.1 - 2.9e-29 101.3 0.2 9.3e-29 99.7 0.1 1.9 2 0 0 2 2 2 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 KFL62236.1 - 2.1e-19 69.7 0.0 1.2e-18 67.3 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Sec1 PF00995.23 KFL62237.1 - 2.7e-110 370.3 0.0 3.3e-110 370.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Transposase_22 PF02994.14 KFL62237.1 - 0.0046 17.1 0.0 0.15 12.2 0.0 2.8 3 0 0 3 3 3 1 L1 transposable element RBD-like domain Sec1 PF00995.23 KFL62238.1 - 2.2e-97 327.6 0.0 2.7e-97 327.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Transposase_22 PF02994.14 KFL62238.1 - 0.0037 17.4 0.0 0.14 12.4 0.0 2.8 3 0 0 3 3 3 1 L1 transposable element RBD-like domain MKT1_N PF12247.8 KFL62241.1 - 5.7e-19 68.3 0.0 1.3e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 KFL62241.1 - 5.9e-06 26.6 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region GIT_SHD PF08518.11 KFL62241.1 - 0.015 14.9 0.2 0.033 13.8 0.2 1.5 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT XPG_N PF00752.17 KFL62241.1 - 0.13 12.8 0.0 0.44 11.0 0.0 1.9 2 0 0 2 2 2 0 XPG N-terminal domain MKT1_N PF12247.8 KFL62242.1 - 2.6e-19 69.4 0.0 7.9e-19 67.8 0.0 1.8 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 KFL62242.1 - 3.7e-06 27.2 0.0 7.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 XPG I-region GIT_SHD PF08518.11 KFL62242.1 - 0.01 15.4 0.2 0.023 14.3 0.2 1.6 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT zf-MYND PF01753.18 KFL62243.1 - 3.6e-08 33.3 20.7 8.9e-08 32.1 20.7 1.7 1 0 0 1 1 1 1 MYND finger ATG16 PF08614.11 KFL62243.1 - 0.26 11.5 4.3 0.087 13.0 1.2 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SOG2 PF10428.9 KFL62243.1 - 0.66 9.1 23.0 0.86 8.7 23.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein 2-Hacid_dh PF00389.30 KFL62245.1 - 1.4e-14 53.9 0.0 1.5e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 KFL62245.1 - 1.5e-05 24.5 0.3 2.2e-05 23.9 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFL62246.1 - 1.4e-14 53.9 0.0 1.5e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 KFL62246.1 - 1.5e-05 24.5 0.3 2.2e-05 23.9 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phosducin PF02114.16 KFL62247.1 - 4.2e-15 55.4 0.0 1.4e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 Phosducin YEATS PF03366.16 KFL62248.1 - 1.1e-15 57.4 0.2 3.4e-14 52.6 0.2 2.3 1 1 0 1 1 1 1 YEATS family BET PF17035.5 KFL62248.1 - 0.071 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation YEATS PF03366.16 KFL62249.1 - 9.1e-16 57.6 0.2 3.1e-14 52.7 0.2 2.3 1 1 0 1 1 1 1 YEATS family BET PF17035.5 KFL62249.1 - 1.9e-06 27.9 0.2 3.3e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation YEATS PF03366.16 KFL62250.1 - 1.3e-19 70.0 0.1 2.2e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KFL62250.1 - 1.9e-06 27.9 0.2 3.3e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation YEATS PF03366.16 KFL62251.1 - 7.9e-16 57.8 0.2 2.8e-14 52.9 0.2 2.3 1 1 0 1 1 1 1 YEATS family BET PF17035.5 KFL62251.1 - 0.061 13.5 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation YEATS PF03366.16 KFL62252.1 - 1.2e-19 70.1 0.1 2e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KFL62252.1 - 0.062 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation YEATS PF03366.16 KFL62253.1 - 1e-19 70.3 0.1 1.8e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KFL62253.1 - 1.6e-06 28.2 0.2 2.7e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Med20 PF08612.11 KFL62253.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex YEATS PF03366.16 KFL62254.1 - 9.2e-20 70.4 0.1 1.6e-19 69.7 0.1 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KFL62254.1 - 0.052 13.7 0.1 0.098 12.8 0.1 1.4 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation YEATS PF03366.16 KFL62255.1 - 6.7e-20 70.8 0.1 9.4e-20 70.4 0.1 1.2 1 0 0 1 1 1 1 YEATS family Med20 PF08612.11 KFL62255.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.3 1 1 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Apolipoprotein PF01442.18 KFL62256.1 - 0.025 14.5 6.6 0.023 14.6 4.7 1.9 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DivIVA PF05103.13 KFL62256.1 - 0.075 13.1 2.3 0.15 12.1 2.3 1.5 1 0 0 1 1 1 0 DivIVA protein Apo-CII PF05355.11 KFL62256.1 - 0.15 12.2 0.5 1.5 9.0 0.2 2.3 1 1 1 2 2 2 0 Apolipoprotein C-II DUF883 PF05957.13 KFL62256.1 - 0.36 11.5 5.0 0.94 10.1 5.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KFL62256.1 - 0.45 11.1 2.6 1.1 9.8 2.0 2.0 1 1 0 1 1 1 0 YtxH-like protein Hamartin PF04388.12 KFL62257.1 - 0.015 14.0 2.4 0.016 13.9 2.4 1.0 1 0 0 1 1 1 0 Hamartin protein SDA1 PF05285.12 KFL62257.1 - 0.51 9.7 9.3 0.59 9.5 9.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KFL62257.1 - 1.8 6.6 10.9 2.1 6.5 10.9 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KFL62257.1 - 6.8 5.9 13.5 8 5.7 13.5 1.1 1 0 0 1 1 1 0 BUD22 DUF3761 PF12587.8 KFL62257.1 - 9.7 6.7 11.8 4 8.0 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3761) Ras PF00071.22 KFL62258.1 - 5.8e-56 188.6 0.2 6.9e-56 188.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL62258.1 - 1.1e-31 109.5 0.0 1.7e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL62258.1 - 9.8e-14 51.2 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFL62258.1 - 8.9e-08 32.2 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFL62258.1 - 3e-07 30.0 0.1 3.8e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFL62258.1 - 1.3e-06 28.1 0.0 4.1e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFL62258.1 - 8.3e-05 22.5 0.2 0.0031 17.5 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 KFL62258.1 - 0.0028 17.4 0.1 0.084 12.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KFL62258.1 - 0.0042 16.7 0.0 0.014 15.0 0.0 1.7 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KFL62258.1 - 0.0079 16.2 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 KFL62258.1 - 0.0085 15.9 0.3 0.24 11.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFL62258.1 - 0.0088 16.3 0.0 0.017 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 KFL62258.1 - 0.0091 15.3 0.5 0.047 13.0 0.0 2.2 3 0 0 3 3 3 1 Septin AAA_16 PF13191.6 KFL62258.1 - 0.011 16.2 0.0 0.015 15.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KFL62258.1 - 0.012 15.1 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KFL62258.1 - 0.017 14.7 0.1 0.034 13.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFL62258.1 - 0.023 14.4 0.3 0.054 13.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFL62258.1 - 0.06 13.3 1.2 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KFL62258.1 - 0.062 13.2 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 NTPase TniB PF05621.11 KFL62258.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KFL62258.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KFL62258.1 - 0.18 12.3 0.1 0.39 11.2 0.0 1.6 2 0 0 2 2 2 0 ABC transporter Ras PF00071.22 KFL62259.1 - 1.1e-43 148.6 0.2 8.8e-37 126.2 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 KFL62259.1 - 9.6e-20 71.0 0.1 7.1e-18 65.0 0.1 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL62259.1 - 2.4e-08 33.6 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL62259.1 - 6.7e-06 25.8 0.0 9.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 KFL62260.1 - 1.9e-52 177.1 0.5 1.2e-35 122.6 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 KFL62260.1 - 2.7e-30 105.0 0.2 1.9e-28 99.1 0.2 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL62260.1 - 2.6e-11 43.3 0.1 2e-09 37.2 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL62260.1 - 2.6e-08 33.6 0.0 3.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFL62260.1 - 7.4e-07 29.2 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFL62260.1 - 3.3e-05 23.4 0.1 5e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFL62260.1 - 0.00016 21.7 0.2 0.0036 17.2 0.1 2.4 1 1 1 3 3 3 1 RsgA GTPase Septin PF00735.18 KFL62260.1 - 0.0043 16.4 0.1 0.019 14.2 0.0 1.9 2 0 0 2 2 2 1 Septin PduV-EutP PF10662.9 KFL62260.1 - 0.0059 16.4 0.1 0.12 12.1 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KFL62260.1 - 0.0096 16.2 0.1 0.014 15.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFL62260.1 - 0.011 15.7 0.1 0.028 14.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KFL62260.1 - 0.016 14.8 0.1 0.028 14.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KFL62260.1 - 0.021 14.6 0.2 0.39 10.4 0.2 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KFL62260.1 - 0.022 15.1 0.0 0.028 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 KFL62260.1 - 0.024 14.2 0.2 0.11 12.1 0.2 1.9 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KFL62260.1 - 0.028 14.2 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFL62260.1 - 0.064 13.2 0.6 0.094 12.6 0.1 1.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 KFL62260.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 KFL62260.1 - 0.095 12.1 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 KFL62260.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KFL62260.1 - 0.18 12.3 0.1 0.24 11.9 0.1 1.4 1 1 0 1 1 1 0 ABC transporter Ras PF00071.22 KFL62261.1 - 3.6e-46 156.7 0.3 4.3e-46 156.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL62261.1 - 2.9e-21 75.9 0.0 4.6e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL62261.1 - 9.3e-09 35.0 0.0 1.2e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL62261.1 - 2.7e-05 23.8 0.0 3.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFL62261.1 - 0.014 14.8 0.1 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 KFL62262.1 - 3e-37 127.7 0.1 3.8e-37 127.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL62262.1 - 8.7e-16 58.2 0.0 1.5e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL62262.1 - 2e-08 33.9 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL62262.1 - 7.1e-06 25.7 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 KFL62263.1 - 3e-37 127.7 0.1 3.8e-37 127.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL62263.1 - 8.7e-16 58.2 0.0 1.5e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL62263.1 - 2e-08 33.9 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL62263.1 - 7.1e-06 25.7 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 KFL62264.1 - 4.4e-55 185.7 0.1 5.2e-55 185.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL62264.1 - 7.7e-32 110.0 0.0 1e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL62264.1 - 1.1e-13 51.0 0.0 1.3e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFL62264.1 - 6.6e-08 32.6 0.0 8.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFL62264.1 - 2.1e-07 30.6 0.0 2.6e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFL62264.1 - 4.9e-06 26.2 0.0 0.00031 20.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFL62264.1 - 0.00011 22.2 0.2 0.0022 17.9 0.1 2.3 1 1 2 3 3 3 1 RsgA GTPase cobW PF02492.19 KFL62264.1 - 0.0029 17.2 0.0 0.0088 15.7 0.0 1.7 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KFL62264.1 - 0.0032 17.2 0.0 0.06 13.1 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KFL62264.1 - 0.0064 16.8 0.0 0.011 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 KFL62264.1 - 0.0068 15.7 0.1 0.035 13.4 0.0 1.9 2 0 0 2 2 2 1 Septin AAA_5 PF07728.14 KFL62264.1 - 0.0069 16.4 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 KFL62264.1 - 0.0088 15.9 0.2 0.28 10.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KFL62264.1 - 0.009 15.5 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KFL62264.1 - 0.014 14.9 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KFL62264.1 - 0.014 15.8 0.0 0.016 15.6 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFL62264.1 - 0.023 14.4 0.1 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFL62264.1 - 0.048 13.6 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 KFL62264.1 - 0.055 13.4 0.6 0.08 12.8 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 KFL62264.1 - 0.06 12.7 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KFL62264.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MCM PF00493.23 KFL62264.1 - 0.14 11.2 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 KFL62264.1 - 0.18 12.4 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Ras PF00071.22 KFL62265.1 - 7.2e-43 146.0 0.1 7.6e-36 123.2 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 KFL62265.1 - 5.5e-20 71.8 0.1 4.2e-18 65.7 0.1 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL62265.1 - 3e-08 33.3 0.0 3.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL62265.1 - 3e-05 23.7 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 KFL62266.1 - 2.5e-37 128.0 0.0 3e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL62266.1 - 3.8e-15 56.2 0.0 6.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL62266.1 - 3.2e-08 33.2 0.0 3.8e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL62266.1 - 3.6e-05 23.4 0.0 5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFL62266.1 - 0.05 13.0 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 KFL62267.1 - 2.5e-37 128.0 0.0 3e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL62267.1 - 3.8e-15 56.2 0.0 6.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL62267.1 - 3.2e-08 33.2 0.0 3.8e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL62267.1 - 3.6e-05 23.4 0.0 5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFL62267.1 - 0.05 13.0 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 KFL62268.1 - 3.9e-36 124.1 0.6 1.9e-33 115.4 0.6 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFL62268.1 - 3.3e-28 98.3 1.0 2.6e-26 92.2 1.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFL62268.1 - 5.4e-07 29.7 0.0 7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KFL62268.1 - 2e-06 27.4 0.3 0.00017 21.1 0.3 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL62268.1 - 3.9e-06 26.5 0.0 4.8e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFL62268.1 - 0.0006 19.8 0.1 0.0025 17.7 0.1 1.8 1 1 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KFL62268.1 - 0.00082 18.8 0.1 0.0012 18.2 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KFL62268.1 - 0.0075 16.5 0.0 0.0095 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 KFL62268.1 - 0.008 15.5 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_7 PF12775.7 KFL62268.1 - 0.01 15.4 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KFL62268.1 - 0.011 15.7 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFL62268.1 - 0.015 15.7 0.0 0.023 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFL62268.1 - 0.021 14.6 0.1 0.035 13.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KFL62268.1 - 0.044 13.4 0.2 0.061 12.9 0.2 1.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KFL62268.1 - 0.045 13.7 0.1 0.062 13.2 0.1 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 KFL62268.1 - 0.048 13.4 0.1 0.078 12.7 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 KFL62268.1 - 0.067 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 KFL62268.1 - 0.079 12.4 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 KFL62268.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 NACHT domain MCM PF00493.23 KFL62268.1 - 0.11 11.5 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 MCM P-loop domain NB-ARC PF00931.22 KFL62268.1 - 0.14 11.3 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KFL62268.1 - 0.15 12.6 0.1 0.24 11.9 0.2 1.2 1 1 0 1 1 1 0 ABC transporter Ras PF00071.22 KFL62269.1 - 2.5e-45 154.0 0.1 2.9e-45 153.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL62269.1 - 1.9e-21 76.5 0.0 2.6e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL62269.1 - 1e-08 34.8 0.0 1.1e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL62269.1 - 0.00011 21.8 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFL62269.1 - 0.0091 15.4 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Glyco_hydro_75 PF07335.11 KFL62269.1 - 0.13 12.5 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 Ras PF00071.22 KFL62270.1 - 2.2e-36 124.9 0.0 2.7e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL62270.1 - 5.8e-16 58.8 0.0 8.5e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL62270.1 - 2.2e-08 33.7 0.0 2.6e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL62270.1 - 2.9e-05 23.7 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Glyco_hydro_75 PF07335.11 KFL62270.1 - 0.12 12.6 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 Ras PF00071.22 KFL62271.1 - 2.2e-36 124.9 0.0 2.7e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFL62271.1 - 5.8e-16 58.8 0.0 8.5e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFL62271.1 - 2.2e-08 33.7 0.0 2.6e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFL62271.1 - 2.9e-05 23.7 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Glyco_hydro_75 PF07335.11 KFL62271.1 - 0.12 12.6 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 Fungal_trans PF04082.18 KFL62275.1 - 5.8e-45 153.4 0.0 1.3e-44 152.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MnmE_helical PF12631.7 KFL62275.1 - 0.15 12.2 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 MnmE helical domain Metallophos PF00149.28 KFL62276.1 - 1.1e-31 110.9 0.0 4.2e-22 79.7 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFL62276.1 - 0.087 13.3 0.1 0.23 11.9 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 KFL62277.1 - 0.038 14.1 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 Pkinase PF00069.25 KFL62278.1 - 2.6e-60 204.0 0.0 4.1e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62278.1 - 2.7e-35 121.9 0.0 4.7e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFL62278.1 - 1e-20 73.3 27.8 6.4e-12 45.2 9.0 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFL62278.1 - 7.4e-15 55.4 1.1 6.5e-14 52.4 1.7 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KFL62278.1 - 1.1e-07 32.0 0.0 2.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KFL62278.1 - 0.021 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-RING_9 PF13901.6 KFL62278.1 - 1.7 8.6 22.2 1.2 9.0 7.7 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon TFIIA PF03153.13 KFL62278.1 - 3.6 7.5 31.6 0.55 10.2 27.6 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 KFL62279.1 - 3.1e-42 144.8 0.1 5.2e-42 144.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62279.1 - 1.3e-24 86.9 0.0 2.3e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFL62279.1 - 6.5e-21 74.0 27.8 5.2e-12 45.5 9.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 KFL62279.1 - 8.5e-08 32.4 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 KFL62279.1 - 0.16 10.9 0.2 0.71 8.8 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 KFL62279.1 - 0.2 11.2 0.1 0.2 11.2 0.1 2.5 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 zf-RING_9 PF13901.6 KFL62279.1 - 0.93 9.4 22.0 1 9.3 7.7 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon TFIIA PF03153.13 KFL62279.1 - 1.2 9.1 30.6 0.44 10.5 27.7 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 KFL62280.1 - 3.1e-42 144.8 0.1 5.2e-42 144.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62280.1 - 1.3e-24 86.9 0.0 2.3e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFL62280.1 - 6.5e-21 74.0 27.8 5.2e-12 45.5 9.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 KFL62280.1 - 8.5e-08 32.4 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 KFL62280.1 - 0.16 10.9 0.2 0.71 8.8 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 KFL62280.1 - 0.2 11.2 0.1 0.2 11.2 0.1 2.5 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 zf-RING_9 PF13901.6 KFL62280.1 - 0.93 9.4 22.0 1 9.3 7.7 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon TFIIA PF03153.13 KFL62280.1 - 1.2 9.1 30.6 0.44 10.5 27.7 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 KFL62281.1 - 1.6e-60 204.7 0.0 2.5e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62281.1 - 1.7e-35 122.5 0.0 3e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFL62281.1 - 5.5e-21 74.2 27.8 4.8e-12 45.6 9.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFL62281.1 - 1.7e-12 47.8 1.7 1.7e-11 44.7 2.1 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFL62281.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TFIIA PF03153.13 KFL62281.1 - 0.19 11.7 27.3 0.28 11.1 27.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_9 PF13901.6 KFL62281.1 - 0.81 9.6 22.0 0.94 9.4 7.7 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_2 PF13831.6 KFL62281.1 - 9.4 5.9 16.2 14 5.4 3.5 2.7 2 0 0 2 2 2 0 PHD-finger Pkinase PF00069.25 KFL62282.1 - 1.6e-60 204.7 0.0 2.5e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62282.1 - 1.7e-35 122.5 0.0 3e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFL62282.1 - 5.5e-21 74.2 27.8 4.8e-12 45.6 9.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFL62282.1 - 1.7e-12 47.8 1.7 1.7e-11 44.7 2.1 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFL62282.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TFIIA PF03153.13 KFL62282.1 - 0.19 11.7 27.3 0.28 11.1 27.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_9 PF13901.6 KFL62282.1 - 0.81 9.6 22.0 0.94 9.4 7.7 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_2 PF13831.6 KFL62282.1 - 9.4 5.9 16.2 14 5.4 3.5 2.7 2 0 0 2 2 2 0 PHD-finger Pkinase PF00069.25 KFL62283.1 - 1.6e-60 204.7 0.0 2.5e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62283.1 - 1.7e-35 122.5 0.0 3e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFL62283.1 - 5.5e-21 74.2 27.8 4.8e-12 45.6 9.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFL62283.1 - 1.7e-12 47.8 1.7 1.7e-11 44.7 2.1 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFL62283.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TFIIA PF03153.13 KFL62283.1 - 0.19 11.7 27.3 0.28 11.1 27.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_9 PF13901.6 KFL62283.1 - 0.81 9.6 22.0 0.94 9.4 7.7 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_2 PF13831.6 KFL62283.1 - 9.4 5.9 16.2 14 5.4 3.5 2.7 2 0 0 2 2 2 0 PHD-finger Pkinase PF00069.25 KFL62284.1 - 1.6e-60 204.7 0.0 2.5e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62284.1 - 1.7e-35 122.5 0.0 3e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFL62284.1 - 5.5e-21 74.2 27.8 4.8e-12 45.6 9.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFL62284.1 - 1.7e-12 47.8 1.7 1.7e-11 44.7 2.1 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFL62284.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TFIIA PF03153.13 KFL62284.1 - 0.19 11.7 27.3 0.28 11.1 27.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_9 PF13901.6 KFL62284.1 - 0.81 9.6 22.0 0.94 9.4 7.7 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_2 PF13831.6 KFL62284.1 - 9.4 5.9 16.2 14 5.4 3.5 2.7 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 KFL62285.1 - 6.1e-21 74.1 27.8 4.6e-12 45.6 9.0 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 KFL62285.1 - 3.8e-14 52.7 0.2 6.3e-14 52.0 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62285.1 - 4.7e-09 35.9 0.2 8.9e-09 35.0 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 KFL62285.1 - 7.3e-08 32.6 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain TFIIA PF03153.13 KFL62285.1 - 0.64 9.9 30.1 0.25 11.3 27.2 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-RING_9 PF13901.6 KFL62285.1 - 0.74 9.8 22.0 0.91 9.5 7.7 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_2 PF13831.6 KFL62285.1 - 9.1 5.9 16.2 13 5.4 3.5 2.7 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 KFL62286.1 - 6.1e-21 74.1 27.8 4.6e-12 45.6 9.0 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 KFL62286.1 - 3.8e-14 52.7 0.2 6.3e-14 52.0 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62286.1 - 4.7e-09 35.9 0.2 8.9e-09 35.0 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 KFL62286.1 - 7.3e-08 32.6 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain TFIIA PF03153.13 KFL62286.1 - 0.64 9.9 30.1 0.25 11.3 27.2 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-RING_9 PF13901.6 KFL62286.1 - 0.74 9.8 22.0 0.91 9.5 7.7 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_2 PF13831.6 KFL62286.1 - 9.1 5.9 16.2 13 5.4 3.5 2.7 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 KFL62287.1 - 6.1e-21 74.1 27.8 4.6e-12 45.6 9.0 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 KFL62287.1 - 3.8e-14 52.7 0.2 6.3e-14 52.0 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62287.1 - 4.7e-09 35.9 0.2 8.9e-09 35.0 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 KFL62287.1 - 7.3e-08 32.6 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain TFIIA PF03153.13 KFL62287.1 - 0.64 9.9 30.1 0.25 11.3 27.2 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-RING_9 PF13901.6 KFL62287.1 - 0.74 9.8 22.0 0.91 9.5 7.7 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_2 PF13831.6 KFL62287.1 - 9.1 5.9 16.2 13 5.4 3.5 2.7 2 0 0 2 2 2 0 PHD-finger ATP-synt_D PF01813.17 KFL62288.1 - 4e-70 235.7 1.4 5.8e-70 235.1 1.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 KFL62288.1 - 0.041 13.4 0.3 0.065 12.7 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) DUF3919 PF13057.6 KFL62288.1 - 0.054 13.1 0.7 0.08 12.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) SYCE1 PF15233.6 KFL62288.1 - 0.069 13.2 5.3 0.05 13.7 2.2 2.1 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 ATP-synt_D PF01813.17 KFL62289.1 - 6.3e-49 166.5 0.3 7.6e-49 166.2 0.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit D LepB_GAP_C PF18227.1 KFL62289.1 - 0.04 14.4 0.4 3.5 8.2 0.1 2.8 2 1 1 3 3 3 0 LepB GAP domain C-terminal subdomain GAS PF13851.6 KFL62289.1 - 0.15 11.4 0.1 0.68 9.3 0.1 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sec7 PF01369.20 KFL62290.1 - 1.3e-60 204.2 0.0 2.1e-60 203.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFL62290.1 - 1.1e-21 77.3 0.0 3.8e-20 72.4 0.0 2.9 2 1 1 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KFL62290.1 - 0.0033 17.1 0.9 0.0033 17.1 0.9 2.1 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7 PF01369.20 KFL62291.1 - 1.3e-60 204.2 0.0 2.1e-60 203.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFL62291.1 - 1.1e-21 77.3 0.0 3.8e-20 72.4 0.0 2.9 2 1 1 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KFL62291.1 - 0.0033 17.1 0.9 0.0033 17.1 0.9 2.1 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7 PF01369.20 KFL62292.1 - 1.2e-60 204.4 0.0 1.8e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFL62292.1 - 1.2e-20 74.0 0.0 3.3e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KFL62292.1 - 0.0029 17.3 0.9 0.0029 17.3 0.9 1.9 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 RhoGEF PF00621.20 KFL62297.1 - 3.6e-19 69.7 0.0 6.3e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 KFL62297.1 - 1.8e-05 24.5 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Nod1 PF17114.5 KFL62297.1 - 0.013 15.7 0.0 0.23 11.6 0.0 2.7 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 Lon_C PF05362.13 KFL62298.1 - 2.2e-66 223.3 0.5 4.5e-66 222.3 0.5 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KFL62298.1 - 1.6e-25 90.2 0.1 4.2e-25 88.8 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KFL62298.1 - 4.4e-24 85.4 0.0 3.2e-23 82.6 0.0 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFL62298.1 - 1e-07 32.0 0.0 3.7e-07 30.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KFL62298.1 - 1.1e-06 28.4 0.0 2.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KFL62298.1 - 2e-06 28.3 0.1 1e-05 26.0 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KFL62298.1 - 6.4e-06 26.0 0.0 1.8e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KFL62298.1 - 1.7e-05 24.2 0.0 4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 KFL62298.1 - 6.6e-05 22.8 0.0 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFL62298.1 - 0.00034 20.4 0.1 0.0012 18.6 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFL62298.1 - 0.00068 19.8 0.0 0.0039 17.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFL62298.1 - 0.00099 19.4 0.2 0.011 16.0 0.0 2.8 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.6 KFL62298.1 - 0.0063 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Birna_VP4 PF01768.16 KFL62298.1 - 0.0065 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Birnavirus VP4 protein AAA_14 PF13173.6 KFL62298.1 - 0.013 15.5 0.0 0.047 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFL62298.1 - 0.013 15.9 0.0 0.054 13.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KFL62298.1 - 0.016 15.1 0.1 0.084 12.8 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 KFL62298.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFL62298.1 - 0.022 14.1 0.1 0.058 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KFL62298.1 - 0.025 15.1 0.6 0.24 11.9 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 KFL62298.1 - 0.03 14.9 0.1 0.085 13.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFL62298.1 - 0.036 14.0 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 KFL62298.1 - 0.038 13.4 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 KFL62298.1 - 0.039 14.3 0.6 0.21 11.9 0.3 2.4 2 1 0 2 2 1 0 AAA domain AAA_PrkA PF08298.11 KFL62298.1 - 0.041 12.8 0.1 0.17 10.7 0.1 1.9 1 1 0 1 1 1 0 PrkA AAA domain PhoH PF02562.16 KFL62298.1 - 0.043 13.3 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 KFL62298.1 - 0.048 13.7 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KFL62298.1 - 0.057 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFL62298.1 - 0.072 12.9 0.1 0.072 12.9 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 KFL62298.1 - 0.095 12.4 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFL62298.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFL62298.1 - 0.12 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 KFL62298.1 - 0.13 11.5 0.1 0.28 10.4 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 KFL62298.1 - 0.15 12.6 0.1 0.15 12.6 0.1 3.0 1 1 1 2 2 1 0 AAA domain Laps PF10169.9 KFL62298.1 - 1.1 9.8 3.3 3.9 8.1 0.0 2.5 1 1 1 2 2 2 0 Learning-associated protein Lon_C PF05362.13 KFL62299.1 - 1.3e-67 227.3 0.4 2.8e-67 226.2 0.4 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KFL62299.1 - 2.5e-24 86.2 0.0 2.2e-23 83.1 0.0 2.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFL62299.1 - 6.6e-08 32.6 0.0 2.6e-07 30.7 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) LON_substr_bdg PF02190.16 KFL62299.1 - 6.9e-07 29.4 0.9 1.3e-06 28.4 0.1 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 KFL62299.1 - 7.8e-07 29.0 0.0 1.8e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KFL62299.1 - 1.6e-06 28.6 0.1 7.3e-06 26.5 0.1 2.2 2 0 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KFL62299.1 - 4.5e-06 26.5 0.0 1.3e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KFL62299.1 - 1.2e-05 24.8 0.0 3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 KFL62299.1 - 4.3e-05 23.4 0.0 0.00013 21.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFL62299.1 - 0.00024 20.9 0.1 0.00091 19.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFL62299.1 - 0.00037 20.7 0.0 0.0029 17.8 0.0 2.6 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFL62299.1 - 0.00063 20.0 0.2 0.0088 16.3 0.0 2.8 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.6 KFL62299.1 - 0.0047 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Birna_VP4 PF01768.16 KFL62299.1 - 0.0049 16.7 0.1 0.013 15.3 0.1 1.7 1 1 0 1 1 1 1 Birnavirus VP4 protein RNA_helicase PF00910.22 KFL62299.1 - 0.0088 16.4 0.1 0.041 14.3 0.0 2.2 2 0 0 2 2 1 1 RNA helicase AAA_14 PF13173.6 KFL62299.1 - 0.009 16.0 0.0 0.034 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KFL62299.1 - 0.01 15.7 0.1 0.063 13.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 KFL62299.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFL62299.1 - 0.017 14.5 0.1 0.045 13.1 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFL62299.1 - 0.018 15.6 0.1 0.065 13.8 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 KFL62299.1 - 0.027 13.4 0.1 0.15 10.9 0.1 2.0 1 1 1 2 2 2 0 PrkA AAA domain NACHT PF05729.12 KFL62299.1 - 0.028 14.4 0.0 0.091 12.7 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 KFL62299.1 - 0.029 14.7 0.3 0.15 12.4 0.3 2.2 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KFL62299.1 - 0.032 13.7 0.0 0.083 12.3 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein TniB PF05621.11 KFL62299.1 - 0.032 13.6 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 KFL62299.1 - 0.034 14.1 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KFL62299.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFL62299.1 - 0.054 14.0 2.3 0.18 12.3 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 KFL62299.1 - 0.055 13.2 0.1 0.055 13.2 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 KFL62299.1 - 0.067 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFL62299.1 - 0.085 12.6 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFL62299.1 - 0.086 12.0 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 KFL62299.1 - 0.097 11.9 0.1 0.22 10.8 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 KFL62299.1 - 0.11 12.9 0.1 0.11 12.9 0.1 2.9 1 1 1 2 2 1 0 AAA domain Laps PF10169.9 KFL62299.1 - 0.61 10.7 3.3 2.9 8.5 0.0 2.6 1 1 1 2 2 2 0 Learning-associated protein AMP-binding PF00501.28 KFL62301.1 - 9.9e-36 123.2 0.0 1.8e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFL62301.1 - 2e-09 37.2 1.4 7.5e-09 35.4 0.2 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus vWA-TerF-like PF10138.9 KFL62302.1 - 2.1e-08 34.6 0.0 3.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KFL62302.1 - 0.035 14.4 0.1 0.07 13.4 0.1 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KFL62303.1 - 2e-08 34.6 0.0 3.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KFL62303.1 - 0.034 14.4 0.1 0.068 13.4 0.1 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KFL62304.1 - 1.6e-07 31.6 0.0 2.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KFL62304.1 - 0.048 13.9 0.1 0.096 12.9 0.1 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain FAD_binding_1 PF00667.20 KFL62305.1 - 1.6e-44 152.1 0.0 2.2e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KFL62305.1 - 6.7e-09 36.4 0.0 2.3e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 KFL62306.1 - 1.6e-44 152.1 0.0 2.2e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KFL62306.1 - 6.7e-09 36.4 0.0 2.3e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain SNARE PF05739.19 KFL62307.1 - 8.8e-05 22.4 0.1 0.00027 20.9 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KFL62307.1 - 0.00021 21.0 6.6 0.015 15.0 0.5 2.1 2 0 0 2 2 2 2 Syntaxin MCPsignal PF00015.21 KFL62307.1 - 0.036 13.9 0.5 0.036 13.9 0.5 2.4 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SNARE PF05739.19 KFL62308.1 - 8.3e-05 22.5 0.1 0.00024 21.0 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KFL62308.1 - 0.00016 21.4 8.7 0.0003 20.5 8.7 1.4 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 KFL62308.1 - 0.032 14.0 0.6 0.032 14.0 0.6 2.5 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CDC37_N PF03234.14 KFL62309.1 - 1.5e-50 171.4 2.0 1.5e-50 171.4 2.0 3.2 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KFL62309.1 - 1.7e-41 140.8 0.5 5.1e-41 139.3 0.1 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KFL62309.1 - 2.4e-35 120.6 3.3 2.4e-35 120.6 3.3 2.2 3 0 0 3 3 3 1 Cdc37 C terminal domain MecA_N PF05223.11 KFL62309.1 - 0.0096 16.2 3.1 0.012 15.9 1.2 2.2 2 0 0 2 2 2 1 NTF2-like N-terminal transpeptidase domain DUF2680 PF10925.8 KFL62309.1 - 0.57 10.2 4.1 5.2 7.1 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) His_Phos_2 PF00328.22 KFL62312.1 - 0.0051 16.2 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Porin_3 PF01459.22 KFL62313.1 - 4.5e-78 262.4 0.0 5.6e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 KFL62313.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Qn_am_d_aII PF14930.6 KFL62313.1 - 0.14 12.5 0.1 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Porin_3 PF01459.22 KFL62314.1 - 1.5e-60 205.0 0.1 1.7e-60 204.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Qn_am_d_aII PF14930.6 KFL62314.1 - 0.08 13.3 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II DUF4385 PF14328.6 KFL62315.1 - 0.11 12.6 1.7 0.11 12.5 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4385) MIF4G_like PF09088.11 KFL62316.1 - 6.4e-69 231.6 0.4 8.6e-69 231.1 0.4 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KFL62317.1 - 6.2e-66 222.6 0.0 7.3e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 MIF4G like zf-H2C2_2 PF13465.6 KFL62319.1 - 1.2e-16 60.2 17.4 1.3e-07 31.7 2.2 5.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFL62319.1 - 6.2e-15 54.7 20.4 0.0014 18.9 1.6 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFL62319.1 - 3.7e-07 30.4 23.0 0.037 14.9 0.6 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 KFL62319.1 - 0.0019 18.5 3.7 0.23 11.9 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KFL62319.1 - 0.0037 17.4 1.8 3.4 7.8 0.1 3.1 2 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KFL62319.1 - 0.023 14.7 6.6 0.18 11.9 0.5 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.12 KFL62319.1 - 0.47 10.7 3.1 0.99 9.7 0.6 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain zf-LYAR PF08790.11 KFL62319.1 - 2.6 8.0 10.0 35 4.4 0.2 4.5 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger RRM_1 PF00076.22 KFL62320.1 - 8.3e-29 99.2 0.1 1.8e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFL62320.1 - 0.00074 19.6 0.0 0.0048 17.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 KFL62320.1 - 0.0023 17.5 0.0 0.088 12.4 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFL62320.1 - 0.0096 16.0 0.3 0.78 9.9 0.1 2.2 2 0 0 2 2 2 1 Limkain b1 OB_RNB PF08206.11 KFL62320.1 - 0.096 12.4 0.1 6.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain PHM7_cyt PF14703.6 KFL62320.1 - 0.11 12.7 0.1 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter CBFD_NFYB_HMF PF00808.23 KFL62321.1 - 9.7e-13 48.2 0.1 1.4e-12 47.7 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFL62321.1 - 3.3e-10 40.4 0.1 5.1e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KFL62321.1 - 0.054 13.8 0.0 0.074 13.4 0.0 1.2 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Totivirus_coat PF05518.11 KFL62321.1 - 0.46 8.5 5.7 0.5 8.4 5.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein PNP_UDP_1 PF01048.20 KFL62323.1 - 1.8e-29 102.7 0.1 2e-29 102.5 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Connexin PF00029.19 KFL62324.1 - 0.18 11.5 0.1 0.2 11.4 0.1 1.1 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 KFL62324.1 - 0.98 7.6 4.1 1.1 7.5 4.1 1.0 1 0 0 1 1 1 0 CDC45-like protein CDC50 PF03381.15 KFL62325.1 - 2.2e-79 266.9 0.0 3.4e-79 266.3 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CDC50 PF03381.15 KFL62326.1 - 2.2e-67 227.5 0.1 3.6e-67 226.8 0.1 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family FlgD_ig PF13860.6 KFL62326.1 - 0.16 11.9 0.1 16 5.5 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain CDC50 PF03381.15 KFL62327.1 - 1.3e-79 267.6 0.0 2e-79 267.0 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family FlgD_ig PF13860.6 KFL62327.1 - 0.15 12.0 0.1 14 5.6 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain CDC50 PF03381.15 KFL62328.1 - 1.3e-79 267.6 0.0 2e-79 267.1 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family FlgD_ig PF13860.6 KFL62328.1 - 0.15 12.0 0.1 14 5.6 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain CDC50 PF03381.15 KFL62329.1 - 1.2e-67 228.4 0.1 1.8e-67 227.8 0.1 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family FlgD_ig PF13860.6 KFL62329.1 - 0.094 12.6 0.1 12 5.8 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain SPT16 PF08644.11 KFL62330.1 - 8.7e-57 191.5 0.1 2e-56 190.3 0.1 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KFL62330.1 - 1.6e-26 93.3 0.0 2.4e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KFL62330.1 - 0.0058 17.0 0.1 0.02 15.3 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like 5_3_exonuc PF01367.20 KFL62330.1 - 0.11 13.1 0.4 9.4 6.9 0.0 2.6 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Sugar_tr PF00083.24 KFL62332.1 - 1e-102 344.4 15.8 1.2e-102 344.1 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFL62332.1 - 3.5e-32 111.7 21.8 1.4e-31 109.8 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFL62332.1 - 1.9e-08 33.3 21.2 8.4e-06 24.6 6.4 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KFL62332.1 - 0.021 13.7 6.8 0.33 9.7 0.1 2.4 2 0 0 2 2 2 0 MFS_1 like family INSIG PF07281.12 KFL62332.1 - 0.12 12.0 3.6 0.12 12.0 1.9 1.8 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) MFS_3 PF05977.13 KFL62332.1 - 0.17 10.3 3.4 0.71 8.2 0.5 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.24 KFL62333.1 - 2.3e-98 330.0 9.5 2.9e-98 329.7 9.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFL62333.1 - 8.5e-31 107.1 20.0 2.8e-30 105.5 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFL62333.1 - 1.8e-09 36.7 15.2 1.3e-06 27.3 1.0 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein INSIG PF07281.12 KFL62333.1 - 0.0036 17.0 1.9 0.11 12.1 1.9 2.4 2 0 0 2 2 2 1 Insulin-induced protein (INSIG) MFS_1_like PF12832.7 KFL62333.1 - 0.022 13.6 6.8 0.36 9.7 0.1 2.4 2 0 0 2 2 2 0 MFS_1 like family MFS_3 PF05977.13 KFL62333.1 - 0.16 10.4 3.4 0.68 8.3 0.5 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.24 KFL62334.1 - 3.7e-97 326.0 12.3 4.5e-97 325.8 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFL62334.1 - 6.9e-31 107.5 20.1 3e-30 105.3 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFL62334.1 - 3.5e-09 35.7 16.8 1.9e-06 26.7 1.9 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KFL62334.1 - 0.014 14.3 6.4 0.32 9.8 0.0 2.4 2 0 0 2 2 2 0 MFS_1 like family INSIG PF07281.12 KFL62334.1 - 0.036 13.7 1.9 0.11 12.2 1.9 1.8 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) MFS_3 PF05977.13 KFL62334.1 - 0.098 11.0 2.9 0.57 8.5 0.4 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.24 KFL62335.1 - 1.3e-95 320.9 17.1 1.7e-95 320.6 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFL62335.1 - 5.7e-32 111.0 20.5 8.4e-32 110.5 16.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFL62335.1 - 1.1e-10 40.7 14.5 2.4e-06 26.4 5.1 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KFL62335.1 - 0.0012 17.8 3.6 0.24 10.2 0.1 2.3 2 0 0 2 2 2 2 MFS_1 like family INSIG PF07281.12 KFL62335.1 - 0.095 12.3 4.0 0.056 13.1 1.5 1.8 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) Sugar_tr PF00083.24 KFL62336.1 - 3e-91 306.6 10.7 3.8e-91 306.2 10.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFL62336.1 - 1.4e-30 106.4 18.7 2.1e-30 105.8 14.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFL62336.1 - 1.8e-11 43.2 9.3 9.3e-07 27.7 1.0 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein INSIG PF07281.12 KFL62336.1 - 0.0012 18.5 1.4 0.052 13.2 1.5 2.4 2 0 0 2 2 2 1 Insulin-induced protein (INSIG) MFS_1_like PF12832.7 KFL62336.1 - 0.0042 16.0 5.4 0.4 9.5 0.1 2.3 2 1 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 KFL62336.1 - 0.063 11.7 2.9 0.44 8.9 0.4 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.24 KFL62337.1 - 4.6e-90 302.6 13.5 5.8e-90 302.3 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFL62337.1 - 9.8e-31 106.9 18.7 1.6e-30 106.3 14.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFL62337.1 - 2.9e-11 42.6 10.6 1.3e-06 27.3 1.9 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KFL62337.1 - 0.0021 17.0 4.7 0.32 9.8 0.1 2.3 2 1 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 KFL62337.1 - 0.054 11.9 2.9 0.4 9.0 0.4 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector INSIG PF07281.12 KFL62337.1 - 0.066 12.9 3.6 0.047 13.3 1.5 1.8 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) PMT PF02366.18 KFL62338.1 - 2.6e-65 220.4 13.2 2.6e-65 220.4 13.2 2.5 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFL62338.1 - 6.4e-65 218.5 17.2 6.4e-65 218.5 17.2 2.2 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFL62338.1 - 2.4e-35 122.0 0.2 3.7e-35 121.4 0.2 1.2 1 0 0 1 1 1 1 MIR domain PMT PF02366.18 KFL62339.1 - 1.5e-89 299.8 14.7 1.8e-89 299.5 14.7 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 KFL62339.1 - 1.8e-35 122.4 0.2 2.9e-35 121.8 0.2 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KFL62339.1 - 0.00054 20.2 9.8 0.00082 19.6 9.0 1.7 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase HKR_ArcB_TM PF18415.1 KFL62339.1 - 0.84 10.5 3.3 0.59 11.0 0.3 2.3 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain zf-CCHC PF00098.23 KFL62340.1 - 5e-48 159.1 64.8 2.4e-09 36.8 2.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KFL62340.1 - 9.8e-14 50.8 43.2 0.0058 16.3 0.7 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KFL62340.1 - 0.00012 22.0 51.5 0.056 13.4 0.2 6.9 3 2 3 6 6 6 3 Zinc knuckle zf-CCHC_5 PF14787.6 KFL62340.1 - 0.00035 20.2 44.8 0.6 9.9 0.9 7.1 6 1 1 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KFL62340.1 - 0.0043 16.9 48.4 0.05 13.4 1.1 6.9 4 2 3 7 7 7 5 Zinc knuckle zf-CCHC PF00098.23 KFL62341.1 - 9e-33 110.9 57.6 1e-07 31.7 2.6 6.4 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.6 KFL62341.1 - 1.6e-07 30.9 35.7 0.1 12.3 0.7 5.9 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.6 KFL62341.1 - 0.00021 21.2 38.7 0.044 13.8 0.1 5.1 3 1 2 5 5 5 4 Zinc knuckle zf-CCHC_5 PF14787.6 KFL62341.1 - 0.0041 16.8 32.3 0.5 10.1 0.9 5.5 5 1 1 6 6 6 4 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KFL62341.1 - 0.49 10.3 40.2 2.1 8.3 0.7 5.5 3 2 2 5 5 5 0 Zinc knuckle zf-CCHC PF00098.23 KFL62342.1 - 3.2e-35 118.6 43.4 2e-09 37.1 2.0 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.6 KFL62342.1 - 1.2e-10 40.9 29.0 0.0049 16.6 0.7 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 KFL62342.1 - 5.6e-05 23.0 34.5 0.046 13.7 0.2 5.3 3 1 1 4 4 4 2 Zinc knuckle zf-CCHC_5 PF14787.6 KFL62342.1 - 0.00095 18.8 28.8 0.49 10.1 0.9 5.2 4 1 1 5 5 5 4 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KFL62342.1 - 0.0074 16.1 34.0 0.03 14.2 0.7 5.0 4 1 1 5 5 5 4 Zinc knuckle ADK PF00406.22 KFL62344.1 - 2.7e-46 157.4 0.1 3.6e-46 157.0 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 KFL62344.1 - 3.8e-17 62.0 0.0 9.8e-17 60.7 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KFL62344.1 - 2e-13 50.9 1.2 4.3e-13 49.8 0.4 1.7 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 KFL62345.1 - 1.3e-42 145.4 0.1 1.6e-42 145.1 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 KFL62345.1 - 2.9e-17 62.3 0.0 7.9e-17 60.9 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KFL62345.1 - 9.4e-10 39.0 1.5 1.6e-09 38.3 0.4 1.8 1 1 1 2 2 2 1 AAA domain HOOK PF05622.12 KFL62347.1 - 1.1e-27 96.6 20.4 1.5e-27 96.1 20.4 1.1 1 0 0 1 1 1 1 HOOK protein KASH_CCD PF14662.6 KFL62347.1 - 0.00021 21.2 38.9 0.078 12.8 16.4 3.2 1 1 2 3 3 3 3 Coiled-coil region of CCDC155 or KASH DUF730 PF05325.11 KFL62347.1 - 4.4 7.3 6.5 6.1 6.9 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF730) HAP1_N PF04849.13 KFL62347.1 - 5.3 6.2 40.1 32 3.6 40.1 2.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Spc42p PF11544.8 KFL62347.1 - 5.6 7.0 22.9 0.035 14.1 6.3 3.9 2 1 2 4 4 4 0 Spindle pole body component Spc42p DUF3584 PF12128.8 KFL62347.1 - 6.6 4.1 37.5 11 3.4 37.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Pox_A_type_inc PF04508.12 KFL62347.1 - 6.9 6.7 15.9 3.4 7.7 0.2 4.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Bromo_TP PF07524.13 KFL62348.1 - 0.056 13.5 0.2 0.17 11.9 0.2 1.8 1 0 0 1 1 1 0 Bromodomain associated PHB_acc_N PF07879.11 KFL62348.1 - 0.13 12.4 1.0 0.28 11.3 0.1 2.0 2 0 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain SecD-TM1 PF13721.6 KFL62348.1 - 0.14 12.7 4.1 0.46 11.0 0.8 2.6 1 1 1 2 2 2 0 SecD export protein N-terminal TM region DUF2203 PF09969.9 KFL62348.1 - 1.5 9.6 16.2 3.4e+02 2.0 16.2 2.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) WDCP PF15390.6 KFL62348.1 - 3.8 5.8 15.4 4.7 5.5 15.4 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family NCE101 PF11654.8 KFL62349.1 - 5.1e-10 38.9 0.0 7e-10 38.5 0.0 1.4 1 1 0 1 1 1 1 Non-classical export protein 1 HSP70 PF00012.20 KFL62351.1 - 5e-260 863.8 7.0 6.1e-260 863.6 7.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62351.1 - 2.1e-16 59.7 0.1 1.8e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KFL62351.1 - 0.0032 17.2 0.0 0.0095 15.7 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KFL62351.1 - 0.013 15.9 4.3 4.8 7.6 0.0 3.5 3 2 0 3 3 3 0 Cell division protein FtsA BcrAD_BadFG PF01869.20 KFL62351.1 - 0.026 14.0 0.1 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 KFL62351.1 - 0.034 13.4 0.1 0.071 12.4 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase HSP70 PF00012.20 KFL62352.1 - 7.5e-261 866.6 6.8 8.4e-261 866.4 6.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62352.1 - 2e-16 59.7 0.1 1.8e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KFL62352.1 - 0.0032 17.2 0.0 0.0094 15.7 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KFL62352.1 - 0.014 15.8 4.5 4.8 7.7 0.0 3.5 3 2 0 3 3 3 0 Cell division protein FtsA BcrAD_BadFG PF01869.20 KFL62352.1 - 0.025 14.1 0.1 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 KFL62352.1 - 0.033 13.4 0.1 0.07 12.4 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase HSP70 PF00012.20 KFL62353.1 - 8.1e-231 767.4 6.5 9.2e-231 767.2 6.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62353.1 - 1e-15 57.4 0.0 1.7e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 KFL62353.1 - 0.0027 17.5 0.0 0.0091 15.7 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KFL62353.1 - 0.032 13.5 0.1 0.068 12.4 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 KFL62353.1 - 0.094 11.9 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 StbA protein Transp_cyt_pur PF02133.15 KFL62354.1 - 7.7e-19 67.8 10.4 8.7e-19 67.6 10.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TMEM239 PF15841.5 KFL62354.1 - 0.83 9.6 5.2 4.9 7.0 0.3 2.2 2 0 0 2 2 2 0 Transmembrane protein 239 family Transp_cyt_pur PF02133.15 KFL62355.1 - 4.7e-18 65.2 2.3 5.3e-18 65.0 2.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.15 KFL62356.1 - 2.2e-12 46.5 0.3 2.7e-12 46.2 0.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin VTC PF09359.10 KFL62357.1 - 1.7e-70 237.6 0.2 1.7e-70 237.6 0.2 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 KFL62357.1 - 8.6e-12 45.7 6.5 2.4e-06 27.8 0.0 3.6 2 1 1 3 3 3 2 SPX domain RAP1 PF07218.11 KFL62357.1 - 0.1 10.9 0.1 0.1 10.9 0.1 1.5 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) DUF202 PF02656.15 KFL62358.1 - 5.2e-12 46.0 5.1 5.7e-12 45.9 1.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) VTC PF09359.10 KFL62358.1 - 0.0047 16.4 0.1 0.0074 15.7 0.1 1.3 1 0 0 1 1 1 1 VTC domain Cation_efflux PF01545.21 KFL62358.1 - 0.049 13.3 0.1 0.08 12.7 0.1 1.2 1 0 0 1 1 1 0 Cation efflux family NCE101 PF11654.8 KFL62358.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 FMN_dh PF01070.18 KFL62359.1 - 5.4e-104 348.0 0.0 6.2e-104 347.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFL62359.1 - 1.5e-07 30.7 0.2 0.00019 20.6 0.0 2.4 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFL62359.1 - 2e-06 27.2 0.0 4.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KFL62359.1 - 0.0037 16.7 0.4 0.033 13.6 0.1 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KFL62359.1 - 0.02 14.3 0.0 0.048 13.1 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KFL62359.1 - 0.18 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Sec3_C_2 PF15278.6 KFL62359.1 - 0.2 12.0 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 Sec3 exocyst complex subunit FMN_dh PF01070.18 KFL62360.1 - 6.1e-104 347.8 0.0 7.1e-104 347.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFL62360.1 - 1.3e-07 31.0 0.3 0.0002 20.5 0.0 2.4 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFL62360.1 - 1.9e-06 27.3 0.0 3.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KFL62360.1 - 0.0034 16.8 0.3 0.032 13.6 0.1 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KFL62360.1 - 0.019 14.5 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KFL62360.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family FMN_dh PF01070.18 KFL62361.1 - 6.1e-104 347.8 0.0 7.1e-104 347.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFL62361.1 - 1.3e-07 31.0 0.3 0.0002 20.5 0.0 2.4 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFL62361.1 - 1.9e-06 27.3 0.0 3.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KFL62361.1 - 0.0034 16.8 0.3 0.032 13.6 0.1 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KFL62361.1 - 0.019 14.5 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KFL62361.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family FMN_dh PF01070.18 KFL62362.1 - 3.2e-95 319.1 0.0 3.9e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFL62362.1 - 1.4e-07 30.8 0.2 0.00017 20.7 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFL62362.1 - 2.7e-06 26.8 0.7 3.5e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 KFL62362.1 - 0.0027 17.2 0.2 0.03 13.7 0.0 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KFL62362.1 - 0.021 14.3 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KFL62362.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family FMN_dh PF01070.18 KFL62363.1 - 3.2e-95 319.1 0.0 3.9e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFL62363.1 - 1.4e-07 30.8 0.2 0.00017 20.7 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFL62363.1 - 2.7e-06 26.8 0.7 3.5e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 KFL62363.1 - 0.0027 17.2 0.2 0.03 13.7 0.0 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KFL62363.1 - 0.021 14.3 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KFL62363.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family FMN_dh PF01070.18 KFL62364.1 - 3.2e-95 319.1 0.0 3.9e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFL62364.1 - 1.4e-07 30.8 0.2 0.00017 20.7 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFL62364.1 - 2.7e-06 26.8 0.7 3.5e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 KFL62364.1 - 0.0027 17.2 0.2 0.03 13.7 0.0 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KFL62364.1 - 0.021 14.3 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KFL62364.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Cauli_VI PF01693.16 KFL62365.1 - 8.4e-39 131.6 7.8 3.7e-20 71.9 0.6 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 KFL62365.1 - 0.035 14.3 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 RNase H Na_H_Exchanger PF00999.21 KFL62366.1 - 2.4e-45 155.0 22.8 3.5e-45 154.4 22.8 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-C3HC4 PF00097.25 KFL62367.1 - 9.1e-06 25.5 9.4 1.9e-05 24.4 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFL62367.1 - 2.5e-05 24.2 5.2 2.5e-05 24.2 5.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFL62367.1 - 0.00013 22.2 11.6 0.0028 17.9 5.7 2.5 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 KFL62367.1 - 0.00036 20.4 6.5 0.00097 19.0 6.6 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFL62367.1 - 0.00093 19.0 8.4 0.0024 17.7 8.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFL62367.1 - 0.002 17.9 6.2 0.002 17.9 6.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFL62367.1 - 0.0024 18.0 8.7 0.013 15.6 8.9 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFL62367.1 - 3.2 8.1 7.5 17 5.8 7.5 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain Chs7 PF12271.8 KFL62368.1 - 4.4e-90 301.9 12.2 5.3e-90 301.7 12.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone MpPF26 PF07666.11 KFL62368.1 - 0.011 15.9 3.3 0.011 15.9 3.3 2.9 3 2 0 3 3 3 0 M penetrans paralogue family 26 DUF2569 PF10754.9 KFL62368.1 - 0.042 14.3 18.1 0.023 15.2 6.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) UPF0220 PF05255.11 KFL62368.1 - 0.2 11.2 5.1 0.18 11.4 1.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) EMP70 PF02990.16 KFL62368.1 - 3.3 6.3 13.3 0.092 11.4 5.5 1.9 2 0 0 2 2 2 0 Endomembrane protein 70 TssN PF17555.2 KFL62368.1 - 5 6.4 14.6 0.28 10.5 3.1 2.5 2 1 0 2 2 2 0 Type VI secretion system, TssN Chs7 PF12271.8 KFL62369.1 - 7.3e-78 261.8 1.2 9e-78 261.5 1.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone MpPF26 PF07666.11 KFL62369.1 - 0.0047 17.0 0.2 0.0047 17.0 0.2 2.6 3 1 0 3 3 3 1 M penetrans paralogue family 26 DUF2569 PF10754.9 KFL62369.1 - 0.0081 16.6 8.3 0.067 13.6 0.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2569) UPF0220 PF05255.11 KFL62369.1 - 0.066 12.8 1.3 0.12 11.9 1.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) PsbW PF07123.12 KFL62369.1 - 0.15 12.1 1.4 0.98 9.4 0.2 2.1 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) MASE3 PF17159.4 KFL62369.1 - 0.61 9.7 8.8 0.11 12.1 4.6 1.6 1 1 1 2 2 2 0 Membrane-associated sensor domain EMP70 PF02990.16 KFL62369.1 - 4.8 5.7 8.5 0.24 10.0 1.6 1.9 2 0 0 2 2 2 0 Endomembrane protein 70 UCH_C PF18031.1 KFL62370.1 - 0.038 13.9 0.4 0.057 13.3 0.4 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases Importin_rep_6 PF18829.1 KFL62371.1 - 0.15 12.2 1.4 0.3 11.2 0.1 2.0 2 0 0 2 2 2 0 Importin repeat 6 Ge1_WD40 PF16529.5 KFL62371.1 - 0.16 10.9 0.0 0.44 9.4 0.0 1.7 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4239 PF14023.6 KFL62371.1 - 0.23 11.1 1.5 0.58 9.9 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Importin_rep_6 PF18829.1 KFL62372.1 - 0.14 12.3 1.4 0.28 11.3 0.1 2.0 2 0 0 2 2 2 0 Importin repeat 6 Ge1_WD40 PF16529.5 KFL62372.1 - 0.14 11.1 0.0 0.39 9.6 0.0 1.7 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4239 PF14023.6 KFL62372.1 - 0.22 11.2 1.5 0.54 10.0 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) CTP_transf_1 PF01148.20 KFL62373.1 - 9.8e-82 274.7 21.8 1.2e-81 274.4 21.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family CTP_transf_1 PF01148.20 KFL62374.1 - 9.7e-82 274.7 21.8 1.2e-81 274.4 21.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family CTP_transf_1 PF01148.20 KFL62375.1 - 2.5e-78 263.5 20.3 3.1e-78 263.2 20.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF202 PF02656.15 KFL62375.1 - 1.4 9.4 4.9 1.9 9.0 0.2 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Asp PF00026.23 KFL62377.1 - 1.6e-65 221.6 0.1 2.1e-65 221.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFL62377.1 - 2.8e-14 53.8 0.9 4.6e-11 43.3 1.5 3.0 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFL62377.1 - 2.9e-05 24.6 0.6 0.39 11.4 0.2 4.2 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KFL62377.1 - 0.0011 19.5 0.1 0.52 10.9 0.0 3.6 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KFL62377.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.6 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Asp PF00026.23 KFL62378.1 - 6.9e-18 65.1 0.0 9.5e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KFL62378.1 - 0.047 13.5 0.0 0.097 12.4 0.0 1.5 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Asp PF00026.23 KFL62379.1 - 6.9e-18 65.1 0.0 9.5e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KFL62379.1 - 0.047 13.5 0.0 0.097 12.4 0.0 1.5 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Thiamine_BP PF01910.17 KFL62380.1 - 1.4e-24 85.8 0.0 1.5e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Thiamine-binding protein PH_10 PF15411.6 KFL62381.1 - 4.8e-27 94.7 0.3 8.5e-27 93.9 0.3 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KFL62381.1 - 5.7e-05 23.4 0.0 0.0001 22.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.6 KFL62381.1 - 0.00012 22.0 4.0 0.00021 21.2 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain VWA_2 PF13519.6 KFL62381.1 - 0.00044 20.9 0.0 0.0011 19.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFL62381.1 - 0.00089 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KFL62381.1 - 0.0011 19.2 4.8 0.0019 18.5 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 KFL62381.1 - 0.012 15.2 2.9 0.024 14.3 2.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KFL62381.1 - 0.015 15.2 4.4 0.027 14.3 4.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFL62381.1 - 0.019 14.8 4.2 0.035 13.9 4.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFL62381.1 - 0.034 14.0 1.9 0.07 13.0 1.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFL62381.1 - 0.06 13.7 2.3 0.14 12.4 2.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain PH PF00169.29 KFL62381.1 - 0.089 13.3 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 PH domain Prok-RING_4 PF14447.6 KFL62381.1 - 0.15 11.9 3.3 0.32 10.9 3.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 KFL62381.1 - 0.26 11.6 3.5 0.49 10.8 3.5 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.6 KFL62381.1 - 0.27 11.3 1.3 0.65 10.1 0.1 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 KFL62381.1 - 1.3 9.1 5.8 4.4 7.4 5.8 1.9 1 1 0 1 1 1 0 Zinc-finger Cpn60_TCP1 PF00118.24 KFL62383.1 - 8e-60 202.9 0.1 9e-60 202.7 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NOA36 PF06524.12 KFL62383.1 - 0.82 8.9 2.9 1.1 8.5 2.9 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KFL62383.1 - 1.2 7.1 5.4 1.5 6.8 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cpn60_TCP1 PF00118.24 KFL62384.1 - 9.8e-59 199.3 0.6 1.2e-58 199.0 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family E1_dh PF00676.20 KFL62385.1 - 2.8e-111 371.3 0.1 3.4e-111 371.0 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KFL62385.1 - 7.7e-05 22.0 0.1 0.00013 21.2 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KFL62385.1 - 0.029 14.1 1.9 0.062 13.1 1.9 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KFL62386.1 - 1.1e-108 362.8 0.1 1.2e-108 362.6 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KFL62386.1 - 5.4e-05 22.5 0.1 8.7e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KFL62386.1 - 0.019 14.8 1.9 0.036 13.9 1.9 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KFL62387.1 - 1.1e-108 362.8 0.1 1.2e-108 362.6 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KFL62387.1 - 5.4e-05 22.5 0.1 8.7e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KFL62387.1 - 0.019 14.8 1.9 0.036 13.9 1.9 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KFL62388.1 - 2.1e-54 184.5 0.5 6.2e-54 183.0 0.4 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KFL62388.1 - 0.00012 21.4 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase S4 PF01479.25 KFL62389.1 - 2.4e-15 55.9 0.1 5.8e-15 54.7 0.0 1.7 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.6 KFL62389.1 - 0.098 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 S4 domain PAP1 PF08601.10 KFL62389.1 - 1.1 8.9 24.0 1.6 8.4 24.0 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 DUF572 PF04502.13 KFL62389.1 - 8.3 5.9 22.1 13 5.3 22.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) NAD_binding_1 PF00175.21 KFL62391.1 - 4.1e-08 33.8 0.0 3.1e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFL62391.1 - 0.0036 17.6 0.0 0.0075 16.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFL62391.1 - 0.037 14.1 0.0 0.081 13.0 0.0 1.5 2 0 0 2 2 2 0 Ferric reductase NAD binding domain EF-hand_1 PF00036.32 KFL62393.1 - 2.2e-27 92.5 12.3 7.9e-08 31.3 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFL62393.1 - 1.9e-22 79.5 13.0 1.8e-13 50.7 1.2 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KFL62393.1 - 1.1e-20 71.7 6.4 5.1e-05 22.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFL62393.1 - 6.8e-18 63.3 10.6 1.7e-06 27.2 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFL62393.1 - 1.2e-14 53.9 8.1 6e-05 22.8 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFL62393.1 - 3.6e-06 27.3 0.0 0.0081 16.5 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFL62393.1 - 3.5e-05 23.7 7.5 0.019 14.9 0.3 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFL62393.1 - 0.025 14.9 0.1 0.73 10.2 0.1 2.7 2 1 1 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 KFL62394.1 - 1.5e-25 86.8 12.5 6.8e-08 31.5 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFL62394.1 - 1.2e-19 70.5 6.6 1.4e-13 51.0 1.2 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFL62394.1 - 4.4e-18 63.6 7.4 4.4e-05 23.1 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFL62394.1 - 1.9e-16 58.7 10.5 1.5e-06 27.4 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFL62394.1 - 3.7e-14 52.3 8.0 5.1e-05 23.0 0.1 4.0 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 KFL62394.1 - 2e-05 24.5 4.8 0.027 14.4 0.2 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFL62394.1 - 0.00013 22.3 0.0 0.0061 16.9 0.0 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KFL62394.1 - 0.04 14.3 0.1 0.59 10.5 0.1 2.4 2 1 1 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 KFL62395.1 - 5.9e-26 88.0 12.5 5.3e-08 31.9 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFL62395.1 - 5.5e-20 71.6 6.5 1e-13 51.5 1.2 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFL62395.1 - 2.2e-18 64.6 7.5 3.5e-05 23.4 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFL62395.1 - 6.2e-17 60.2 10.2 1.2e-06 27.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFL62395.1 - 9.7e-15 54.2 7.3 3.9e-05 23.4 0.1 4.0 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 KFL62395.1 - 1.1e-05 25.2 5.1 0.016 15.1 0.3 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFL62395.1 - 6.7e-05 23.2 0.0 0.0042 17.4 0.0 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KFL62395.1 - 0.02 15.2 0.1 0.42 11.0 0.1 2.5 2 1 1 3 3 3 0 EF-hand domain Dockerin_1 PF00404.18 KFL62395.1 - 0.15 12.3 1.2 0.81 9.9 1.2 2.2 1 1 0 1 1 1 0 Dockerin type I domain EF-hand_1 PF00036.32 KFL62396.1 - 2e-19 67.6 11.6 4.9e-08 32.0 0.5 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KFL62396.1 - 1.4e-15 57.5 4.9 8.9e-14 51.7 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFL62396.1 - 5.4e-14 50.9 5.2 3.2e-05 23.5 0.2 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFL62396.1 - 3e-12 45.4 7.5 1.1e-06 27.8 0.3 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFL62396.1 - 9.7e-12 44.6 5.9 3.6e-05 23.5 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KFL62396.1 - 5.2e-05 23.2 5.7 0.01 15.8 0.3 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFL62396.1 - 0.0017 18.6 0.0 0.0032 17.8 0.0 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KFL62396.1 - 0.035 14.4 0.0 0.37 11.1 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 KFL62396.1 - 0.15 12.3 1.2 0.72 10.1 1.2 2.1 1 1 0 1 1 1 0 Dockerin type I domain EF-hand_1 PF00036.32 KFL62397.1 - 2e-19 67.6 11.6 4.9e-08 32.0 0.5 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KFL62397.1 - 1.4e-15 57.5 4.9 8.9e-14 51.7 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFL62397.1 - 5.4e-14 50.9 5.2 3.2e-05 23.5 0.2 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFL62397.1 - 3e-12 45.4 7.5 1.1e-06 27.8 0.3 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFL62397.1 - 9.7e-12 44.6 5.9 3.6e-05 23.5 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KFL62397.1 - 5.2e-05 23.2 5.7 0.01 15.8 0.3 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFL62397.1 - 0.0017 18.6 0.0 0.0032 17.8 0.0 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KFL62397.1 - 0.035 14.4 0.0 0.37 11.1 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 KFL62397.1 - 0.15 12.3 1.2 0.72 10.1 1.2 2.1 1 1 0 1 1 1 0 Dockerin type I domain EF-hand_1 PF00036.32 KFL62398.1 - 2e-19 67.6 11.6 4.9e-08 32.0 0.5 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KFL62398.1 - 1.4e-15 57.5 4.9 8.9e-14 51.7 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFL62398.1 - 5.4e-14 50.9 5.2 3.2e-05 23.5 0.2 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFL62398.1 - 3e-12 45.4 7.5 1.1e-06 27.8 0.3 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFL62398.1 - 9.7e-12 44.6 5.9 3.6e-05 23.5 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KFL62398.1 - 5.2e-05 23.2 5.7 0.01 15.8 0.3 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFL62398.1 - 0.0017 18.6 0.0 0.0032 17.8 0.0 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KFL62398.1 - 0.035 14.4 0.0 0.37 11.1 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 KFL62398.1 - 0.15 12.3 1.2 0.72 10.1 1.2 2.1 1 1 0 1 1 1 0 Dockerin type I domain EF1G PF00647.19 KFL62400.1 - 1.1e-48 163.7 0.3 1.8e-48 163.1 0.3 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KFL62400.1 - 2.2e-12 47.0 0.0 4.6e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFL62400.1 - 4.3e-08 33.1 0.0 1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFL62400.1 - 4.1e-06 26.9 0.0 8.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CPBP PF02517.16 KFL62401.1 - 9.6e-16 57.9 5.7 9.6e-16 57.9 5.7 1.9 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease 2-Hacid_dh_C PF02826.19 KFL62402.1 - 2.1e-49 167.3 0.0 3.3e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFL62402.1 - 3.4e-16 59.1 0.0 5e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 KFL62403.1 - 1.6e-29 102.5 0.0 2.9e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFL62403.1 - 5e-15 55.4 0.0 7.3e-15 54.8 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 KFL62404.1 - 1.6e-29 102.5 0.0 2.9e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFL62404.1 - 5e-15 55.4 0.0 7.3e-15 54.8 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain RNA_pol_L_2 PF13656.6 KFL62405.1 - 3.4e-26 90.8 0.0 4.6e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFL62405.1 - 1.8e-10 40.1 0.0 2.8e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.6 KFL62406.1 - 1e-06 29.4 0.3 1.6e-06 28.7 0.3 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KFL62406.1 - 5.2e-06 26.4 0.5 1e-05 25.5 0.5 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFL62407.1 - 0.00052 20.7 0.1 0.00071 20.3 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KFL62407.1 - 0.0083 16.2 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFL62408.1 - 8.6e-07 29.6 0.4 1.4e-06 29.0 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KFL62408.1 - 4.3e-06 26.7 0.6 8.7e-06 25.7 0.6 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFL62409.1 - 0.00071 20.3 0.2 0.001 19.8 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KFL62409.1 - 0.0058 16.7 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF5301 PF17225.3 KFL62410.1 - 0.01 16.2 0.2 0.031 14.7 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5300) PVL_ORF50 PF07768.11 KFL62410.1 - 2 8.8 11.1 0.71 10.2 8.1 1.7 1 1 1 2 2 2 0 PVL ORF-50-like family DUF3959 PF13105.6 KFL62410.1 - 4.4 6.7 5.9 4.5 6.7 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) Actin PF00022.19 KFL62411.1 - 2.5e-132 441.4 0.0 1e-131 439.3 0.0 1.7 1 1 0 1 1 1 1 Actin Glyco_hydro_18 PF00704.28 KFL62412.1 - 4.2e-78 263.2 7.7 5.2e-78 262.9 7.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PhageMin_Tail PF10145.9 KFL62412.1 - 0.031 14.1 0.2 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Phage-related minor tail protein Glyco_hydro_18 PF00704.28 KFL62413.1 - 6.6e-78 262.6 6.9 8.2e-78 262.3 6.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KFL62414.1 - 1.5e-74 251.6 6.6 1.9e-74 251.2 6.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PhageMin_Tail PF10145.9 KFL62414.1 - 0.031 14.2 0.2 0.099 12.5 0.1 1.8 2 0 0 2 2 2 0 Phage-related minor tail protein Glyco_hydro_18 PF00704.28 KFL62415.1 - 1.7e-81 274.3 8.1 2e-81 274.1 8.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KFL62416.1 - 3.7e-78 263.4 7.7 4.5e-78 263.1 7.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PhageMin_Tail PF10145.9 KFL62416.1 - 0.031 14.2 0.2 0.098 12.5 0.1 1.8 2 0 0 2 2 2 0 Phage-related minor tail protein Glyco_hydro_18 PF00704.28 KFL62417.1 - 6.1e-78 262.7 7.0 7.1e-78 262.5 7.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KFL62418.1 - 1.5e-81 274.5 8.1 1.7e-81 274.4 8.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GARS_A PF01071.19 KFL62419.1 - 4.1e-84 281.2 0.2 8.1e-84 280.2 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KFL62419.1 - 2.1e-36 125.4 0.1 6.7e-36 123.8 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KFL62419.1 - 1e-35 122.4 0.3 2.2e-34 118.1 0.0 3.0 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KFL62419.1 - 1.4e-26 92.5 0.9 4e-26 91.1 0.9 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KFL62419.1 - 1.8e-14 54.1 1.4 6.7e-14 52.3 1.4 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 KFL62419.1 - 0.00084 19.4 0.0 0.0032 17.5 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 KFL62419.1 - 0.00091 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KFL62419.1 - 0.007 15.9 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 KFL62419.1 - 0.0081 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KFL62420.1 - 3e-84 281.7 0.1 6.3e-84 280.6 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KFL62420.1 - 1.6e-36 125.8 0.2 5.3e-36 124.1 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KFL62420.1 - 1.2e-26 92.8 0.9 3.3e-26 91.4 0.9 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KFL62420.1 - 1.8e-14 54.1 1.4 5.5e-14 52.6 1.4 1.8 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 KFL62420.1 - 0.00063 19.8 0.0 0.0025 17.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 KFL62420.1 - 0.00071 19.2 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KFL62420.1 - 0.0055 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 KFL62420.1 - 0.0065 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Pet127 PF08634.10 KFL62421.1 - 3.3e-118 394.1 0.0 4.3e-118 393.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Pet127 PF08634.10 KFL62422.1 - 3.3e-118 394.1 0.0 4.3e-118 393.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Abhydrolase_1 PF00561.20 KFL62428.1 - 1e-25 90.9 0.0 1.2e-25 90.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFL62428.1 - 3.8e-11 42.7 0.0 7.1e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFL62428.1 - 2.3e-06 28.4 0.1 2.9e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KFL62428.1 - 0.15 10.7 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Ndr family Sec10 PF07393.11 KFL62429.1 - 2.6e-125 419.5 0.0 3.4e-125 419.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KFL62429.1 - 1.9e-06 27.7 0.0 4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFL62429.1 - 1.1e-05 25.2 1.1 1.7e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 F-box domain NAD_Gly3P_dh_N PF01210.23 KFL62430.1 - 2.5e-45 154.2 0.0 6e-45 153.0 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KFL62430.1 - 4.1e-43 147.1 0.1 7.1e-43 146.3 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_C PF07479.14 KFL62431.1 - 2.9e-43 147.5 0.1 4.9e-43 146.8 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KFL62431.1 - 1.5e-35 122.5 0.0 2.5e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NMDAR2_C PF10565.9 KFL62431.1 - 0.3 9.9 0.4 0.45 9.3 0.4 1.2 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus PMP1_2 PF08114.11 KFL62432.1 - 0.00094 18.9 2.2 0.00094 18.9 2.2 1.4 1 1 0 1 1 1 1 ATPase proteolipid family DUF4381 PF14316.6 KFL62432.1 - 0.0028 17.9 0.1 0.0035 17.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) NCE101 PF11654.8 KFL62432.1 - 0.013 15.2 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Non-classical export protein 1 5TM-5TMR_LYT PF07694.12 KFL62432.1 - 0.029 13.9 0.2 0.036 13.6 0.2 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Flavi_M PF01004.19 KFL62432.1 - 0.033 14.0 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M SecE PF00584.20 KFL62432.1 - 0.083 12.8 0.3 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Sec61_beta PF03911.16 KFL62432.1 - 0.11 12.6 1.8 0.15 12.1 1.8 1.2 1 0 0 1 1 1 0 Sec61beta family Vma12 PF11712.8 KFL62432.1 - 0.12 12.4 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PMP1_2 PF08114.11 KFL62433.1 - 0.00094 18.9 2.2 0.00094 18.9 2.2 1.4 1 1 0 1 1 1 1 ATPase proteolipid family DUF4381 PF14316.6 KFL62433.1 - 0.0028 17.9 0.1 0.0035 17.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) NCE101 PF11654.8 KFL62433.1 - 0.013 15.2 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Non-classical export protein 1 5TM-5TMR_LYT PF07694.12 KFL62433.1 - 0.029 13.9 0.2 0.036 13.6 0.2 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Flavi_M PF01004.19 KFL62433.1 - 0.033 14.0 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M SecE PF00584.20 KFL62433.1 - 0.083 12.8 0.3 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Sec61_beta PF03911.16 KFL62433.1 - 0.11 12.6 1.8 0.15 12.1 1.8 1.2 1 0 0 1 1 1 0 Sec61beta family Vma12 PF11712.8 KFL62433.1 - 0.12 12.4 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PMP1_2 PF08114.11 KFL62434.1 - 0.00094 18.9 2.2 0.00094 18.9 2.2 1.4 1 1 0 1 1 1 1 ATPase proteolipid family DUF4381 PF14316.6 KFL62434.1 - 0.0028 17.9 0.1 0.0035 17.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) NCE101 PF11654.8 KFL62434.1 - 0.013 15.2 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Non-classical export protein 1 5TM-5TMR_LYT PF07694.12 KFL62434.1 - 0.029 13.9 0.2 0.036 13.6 0.2 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Flavi_M PF01004.19 KFL62434.1 - 0.033 14.0 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M SecE PF00584.20 KFL62434.1 - 0.083 12.8 0.3 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Sec61_beta PF03911.16 KFL62434.1 - 0.11 12.6 1.8 0.15 12.1 1.8 1.2 1 0 0 1 1 1 0 Sec61beta family Vma12 PF11712.8 KFL62434.1 - 0.12 12.4 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Velvet PF11754.8 KFL62435.1 - 4.7e-76 256.0 0.4 6.5e-76 255.6 0.4 1.1 1 0 0 1 1 1 1 Velvet factor DGF-1_C PF11040.8 KFL62435.1 - 0.53 10.3 4.0 0.42 10.6 0.7 2.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus AAA PF00004.29 KFL62438.1 - 1.8e-45 154.6 0.1 8.1e-45 152.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFL62438.1 - 3.5e-10 39.7 0.1 2.1e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KFL62438.1 - 6.8e-09 35.8 0.4 2.2e-08 34.2 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFL62438.1 - 4.8e-08 33.3 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFL62438.1 - 1.3e-07 32.1 0.5 3.7e-05 24.2 0.0 3.0 2 2 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KFL62438.1 - 2.8e-06 26.7 0.0 5.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KFL62438.1 - 4.3e-05 23.8 1.2 0.0088 16.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KFL62438.1 - 0.00022 21.0 0.0 0.00069 19.4 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KFL62438.1 - 0.00036 20.1 0.0 0.0026 17.3 0.1 2.2 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_3 PF17862.1 KFL62438.1 - 0.00039 20.2 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_28 PF13521.6 KFL62438.1 - 0.00041 20.6 0.0 0.0016 18.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFL62438.1 - 0.00057 20.4 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KFL62438.1 - 0.0013 18.7 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KFL62438.1 - 0.0016 18.5 0.1 0.0055 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFL62438.1 - 0.0017 18.7 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KFL62438.1 - 0.002 17.4 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 KFL62438.1 - 0.0036 17.2 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 KFL62438.1 - 0.0053 16.5 0.1 0.014 15.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KFL62438.1 - 0.0058 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFL62438.1 - 0.0076 16.2 0.3 0.11 12.4 0.0 2.6 3 0 0 3 3 2 1 NACHT domain Mg_chelatase PF01078.21 KFL62438.1 - 0.0076 15.6 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFL62438.1 - 0.0091 16.2 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KFL62438.1 - 0.01 15.3 0.0 0.5 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 KFL62438.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KFL62438.1 - 0.025 14.3 0.2 0.055 13.2 0.2 1.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KFL62438.1 - 0.04 13.2 0.8 0.56 9.5 0.0 2.4 3 0 0 3 3 2 0 KaiC Bac_DnaA PF00308.18 KFL62438.1 - 0.044 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 KFL62438.1 - 0.047 13.6 1.1 0.33 10.8 0.0 2.5 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KFL62438.1 - 0.048 13.4 0.0 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.6 KFL62438.1 - 0.053 13.3 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KFL62438.1 - 0.078 12.7 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 KFL62438.1 - 0.078 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 KFL62438.1 - 0.088 12.1 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin AAA_25 PF13481.6 KFL62438.1 - 0.094 12.3 1.3 0.27 10.8 0.1 2.2 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 KFL62438.1 - 0.13 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KFL62438.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Parvo_NS1 PF01057.17 KFL62438.1 - 0.21 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 KFL62439.1 - 2.1e-45 154.4 0.5 6.6e-45 152.8 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFL62439.1 - 2.9e-10 39.9 0.1 1.8e-09 37.4 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KFL62439.1 - 6.1e-09 36.0 0.1 1.9e-08 34.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFL62439.1 - 4e-08 33.6 0.0 8.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFL62439.1 - 1.3e-07 32.2 0.2 3.3e-05 24.3 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KFL62439.1 - 2.4e-06 26.9 0.0 4.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KFL62439.1 - 3.2e-05 24.2 1.1 0.0086 16.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KFL62439.1 - 0.0002 21.2 0.0 0.00058 19.6 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KFL62439.1 - 0.00034 20.4 0.0 0.00075 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 KFL62439.1 - 0.00049 20.6 0.0 0.0012 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFL62439.1 - 0.00059 19.4 0.1 0.0023 17.4 0.1 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 KFL62439.1 - 0.00064 20.0 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KFL62439.1 - 0.0011 18.9 0.0 0.011 15.8 0.0 2.2 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KFL62439.1 - 0.0016 18.8 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KFL62439.1 - 0.0017 17.7 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 KFL62439.1 - 0.0018 18.3 0.0 0.0047 17.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 KFL62439.1 - 0.0028 17.6 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 KFL62439.1 - 0.0044 16.8 0.1 0.012 15.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KFL62439.1 - 0.0048 16.7 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFL62439.1 - 0.0053 16.7 0.2 0.1 12.5 0.0 2.7 3 0 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 KFL62439.1 - 0.0068 15.8 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KFL62439.1 - 0.0081 15.6 0.0 0.44 9.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 KFL62439.1 - 0.0084 16.3 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFL62439.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 KFL62439.1 - 0.02 14.2 0.1 0.49 9.7 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 KFL62439.1 - 0.021 14.5 0.2 0.047 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFL62439.1 - 0.036 14.0 0.8 0.29 11.0 0.0 2.4 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 KFL62439.1 - 0.036 13.9 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_11 PF13086.6 KFL62439.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 KFL62439.1 - 0.058 13.1 0.2 1.1 8.9 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 KFL62439.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 KFL62439.1 - 0.078 12.2 0.1 0.19 11.0 0.0 1.6 2 0 0 2 2 1 0 Zeta toxin AAA_19 PF13245.6 KFL62439.1 - 0.12 12.7 0.1 0.33 11.3 0.1 1.7 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 KFL62439.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KFL62439.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KFL62439.1 - 0.17 11.5 2.3 0.24 10.9 0.1 2.2 2 1 1 3 3 2 0 AAA domain Parvo_NS1 PF01057.17 KFL62439.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 KFL62440.1 - 2e-45 154.4 0.1 4.8e-45 153.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFL62440.1 - 1.8e-09 37.4 0.2 1.1e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KFL62440.1 - 5.1e-09 36.2 0.1 1.4e-08 34.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFL62440.1 - 3.2e-08 33.9 0.0 6.1e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFL62440.1 - 1.4e-07 32.1 0.1 2.3e-05 24.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KFL62440.1 - 2e-06 27.1 0.0 3.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KFL62440.1 - 2.4e-05 24.6 1.1 0.0067 16.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KFL62440.1 - 0.00015 21.6 0.0 0.00045 20.0 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KFL62440.1 - 0.00027 20.7 0.0 0.00061 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_7 PF12775.7 KFL62440.1 - 0.00043 19.9 0.1 0.0018 17.8 0.1 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 KFL62440.1 - 0.00047 20.7 0.0 0.00091 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFL62440.1 - 0.00063 20.0 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KFL62440.1 - 0.00079 19.4 0.0 0.016 15.2 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KFL62440.1 - 0.0012 19.2 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KFL62440.1 - 0.0013 18.0 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 KFL62440.1 - 0.0019 18.3 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KFL62440.1 - 0.0019 18.1 0.0 0.0095 15.9 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 KFL62440.1 - 0.0034 17.1 0.1 0.0094 15.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KFL62440.1 - 0.0042 16.9 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KFL62440.1 - 0.0054 16.1 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KFL62440.1 - 0.0056 16.6 0.7 0.089 12.7 0.0 2.7 2 1 0 3 3 2 1 NACHT domain TniB PF05621.11 KFL62440.1 - 0.0057 16.1 0.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 KFL62440.1 - 0.007 16.5 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFL62440.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KFL62440.1 - 0.018 14.8 0.2 0.037 13.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KFL62440.1 - 0.018 14.4 0.1 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 KFL62440.1 - 0.022 14.7 0.1 0.25 11.2 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 KFL62440.1 - 0.031 14.1 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 KFL62440.1 - 0.049 13.3 0.2 0.92 9.2 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KFL62440.1 - 0.054 13.1 0.6 0.2 11.2 0.1 1.9 1 1 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 KFL62440.1 - 0.063 12.2 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase AAA_11 PF13086.6 KFL62440.1 - 0.063 13.1 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFL62440.1 - 0.065 12.5 0.1 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 KFL62440.1 - 0.11 12.9 0.2 0.27 11.6 0.1 1.7 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 KFL62440.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KFL62440.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 KFL62440.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.23 KFL62441.1 - 9.3e-108 360.4 0.1 1.1e-107 360.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFL62441.1 - 4.4e-15 56.4 1.9 2.4e-09 37.7 0.2 2.8 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFL62441.1 - 8.8e-06 26.3 0.3 0.13 12.9 0.0 3.3 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KFL62441.1 - 0.00078 19.3 0.0 0.011 15.6 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KFL62441.1 - 0.0012 19.3 0.0 2.8 8.6 0.0 3.1 2 2 0 2 2 2 2 gag-polyprotein putative aspartyl protease gp45-slide_C PF09116.10 KFL62441.1 - 0.081 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal Asp PF00026.23 KFL62442.1 - 2.1e-80 270.5 0.3 2.6e-80 270.2 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFL62442.1 - 3.1e-15 56.9 2.0 2.4e-12 47.4 2.0 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFL62442.1 - 9.4e-05 23.0 0.6 0.099 13.3 0.0 3.6 3 2 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KFL62442.1 - 0.012 16.2 0.1 2.1 8.9 0.0 3.0 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease IHHNV_capsid PF16530.5 KFL62442.1 - 0.14 11.2 0.0 2.1 7.4 0.0 2.0 2 0 0 2 2 2 0 Infectious hypodermal and haematopoietic necrosis virus, capsid Biotin_lipoyl_2 PF13533.6 KFL62443.1 - 9.4e-06 25.4 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 KFL62443.1 - 0.0054 16.5 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD_3 PF13437.6 KFL62443.1 - 0.033 14.9 0.0 0.49 11.1 0.0 2.0 2 0 0 2 2 2 0 HlyD family secretion protein NIF PF03031.18 KFL62444.1 - 2.1e-27 95.8 0.0 3.9e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KFL62444.1 - 1.3e-09 38.3 0.0 4.7e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFL62444.1 - 8.7e-08 32.5 0.2 2.8e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KFL62444.1 - 1.1e-05 25.3 0.2 2.6e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 KFL62444.1 - 0.0077 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KFL62444.1 - 0.016 15.2 0.1 0.043 13.9 0.1 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Arginase PF00491.21 KFL62445.1 - 9e-75 251.7 0.3 1e-74 251.6 0.3 1.0 1 0 0 1 1 1 1 Arginase family Arginase PF00491.21 KFL62446.1 - 2.3e-40 138.9 0.0 2.7e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family M_domain PF12938.7 KFL62448.1 - 0.02 14.7 13.8 0.038 13.8 13.8 1.4 1 0 0 1 1 1 0 M domain of GW182 Metal_resist PF13801.6 KFL62448.1 - 0.14 12.4 0.1 0.14 12.4 0.1 3.4 2 1 2 4 4 4 0 Heavy-metal resistance HMG_box PF00505.19 KFL62449.1 - 1.3e-24 86.4 0.5 2.2e-24 85.7 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFL62449.1 - 1.4e-18 67.2 0.9 2.2e-18 66.6 0.9 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KFL62449.1 - 0.00078 20.0 2.5 0.001 19.6 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 KFL62449.1 - 0.013 15.5 1.1 0.014 15.3 0.1 1.6 2 0 0 2 2 2 0 HMG (high mobility group) box 5 CHDNT PF08073.12 KFL62449.1 - 0.042 13.8 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain HMG_box PF00505.19 KFL62450.1 - 1.3e-24 86.4 0.5 2.2e-24 85.7 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFL62450.1 - 1.4e-18 67.2 0.9 2.2e-18 66.6 0.9 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KFL62450.1 - 0.00078 20.0 2.5 0.001 19.6 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 KFL62450.1 - 0.013 15.5 1.1 0.014 15.3 0.1 1.6 2 0 0 2 2 2 0 HMG (high mobility group) box 5 CHDNT PF08073.12 KFL62450.1 - 0.042 13.8 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain HMG_box PF00505.19 KFL62451.1 - 1.3e-24 86.4 0.5 2.2e-24 85.7 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFL62451.1 - 1.4e-18 67.2 0.9 2.2e-18 66.6 0.9 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KFL62451.1 - 0.00078 20.0 2.5 0.001 19.6 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 KFL62451.1 - 0.013 15.5 1.1 0.014 15.3 0.1 1.6 2 0 0 2 2 2 0 HMG (high mobility group) box 5 CHDNT PF08073.12 KFL62451.1 - 0.042 13.8 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain HAT PF02184.16 KFL62453.1 - 0.00019 21.3 0.1 0.00093 19.1 0.1 2.3 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KFL62453.1 - 0.0017 19.0 0.9 0.011 16.5 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFL62453.1 - 0.016 15.8 0.0 0.048 14.3 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat HEPN_RiboL-PSP PF18735.1 KFL62453.1 - 0.15 11.9 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 RiboL-PSP-HEPN Suf PF05843.14 KFL62453.1 - 1.3 8.9 7.0 0.78 9.7 0.1 2.8 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Suf PF05843.14 KFL62454.1 - 1.5e-41 143.4 0.1 1.5e-41 143.4 0.1 2.3 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) Plasmodium_Vir PF05795.11 KFL62454.1 - 0.052 13.0 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM176 PF14851.6 KFL62454.1 - 0.098 12.3 1.7 0.21 11.2 1.7 1.5 1 0 0 1 1 1 0 FAM176 family DUF2031 PF09592.10 KFL62454.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Cdh1_DBD_1 PF18196.1 KFL62454.1 - 0.17 12.2 5.3 0.33 11.3 5.3 1.4 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DUF3391 PF11871.8 KFL62454.1 - 2.5 8.6 7.3 6.7 7.3 7.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Gryzun-like PF12742.7 KFL62455.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking DUF5463 PF17551.2 KFL62457.1 - 0.38 10.7 5.8 0.7 9.9 5.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5463) PITH PF06201.13 KFL62458.1 - 3.6e-35 121.4 0.0 4.4e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain PITH PF06201.13 KFL62459.1 - 3.6e-35 121.4 0.0 4.4e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain zf-C2H2 PF00096.26 KFL62460.1 - 1.2e-12 47.5 13.1 9.3e-07 29.0 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFL62460.1 - 1.3e-07 31.8 10.7 0.0042 17.8 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFL62460.1 - 1e-06 28.8 3.2 0.0082 16.4 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFL62460.1 - 2.2e-06 27.8 14.6 2.5e-06 27.6 3.5 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 KFL62460.1 - 0.00051 20.3 10.2 0.0055 17.1 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFL62460.1 - 0.00083 19.3 11.1 0.013 15.4 0.7 2.7 2 1 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 KFL62460.1 - 0.0024 17.7 3.5 0.13 12.2 0.5 2.6 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-UBR PF02207.20 KFL62460.1 - 0.084 13.0 0.7 0.18 12.0 0.7 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf_UBZ PF18439.1 KFL62460.1 - 0.14 11.8 1.9 0.76 9.4 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFL62460.1 - 0.18 12.2 3.9 6.6 7.1 0.3 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 KFL62460.1 - 0.35 10.5 9.5 0.84 9.3 0.4 3.4 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 KFL62460.1 - 0.4 10.5 8.5 5 7.0 0.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-trcl PF13451.6 KFL62460.1 - 0.42 10.5 4.2 0.57 10.1 0.6 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2H2_3rep PF18868.1 KFL62460.1 - 0.66 10.7 6.5 4.2 8.1 0.9 3.2 2 1 1 3 3 2 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 KFL62460.1 - 1.3 7.5 4.5 8.6 4.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-BED PF02892.15 KFL62460.1 - 1.4 9.0 5.6 0.93 9.6 1.6 2.4 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 KFL62460.1 - 1.8 8.7 4.6 4.5 7.5 0.5 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2HE PF16278.5 KFL62460.1 - 2.2 8.8 6.7 2.6e+02 2.2 6.7 2.7 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Peptidase_M1 PF01433.20 KFL62462.1 - 1.7e-84 282.8 2.8 2.9e-84 282.0 2.8 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFL62462.1 - 2.4e-81 273.7 0.3 3.3e-79 266.7 0.1 2.6 2 0 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFL62462.1 - 2e-52 178.1 1.7 4e-52 177.1 1.7 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KFL62462.1 - 0.16 11.9 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) ERAP1_C PF11838.8 KFL62463.1 - 9.8e-86 288.1 0.1 2.8e-85 286.6 0.1 1.8 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KFL62463.1 - 1.5e-84 282.9 2.8 2.3e-84 282.3 2.8 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFL62463.1 - 3.1e-28 99.2 0.9 6.7e-28 98.1 0.9 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain NGP1NT PF08153.12 KFL62466.1 - 1e-50 171.3 0.1 1.4e-50 170.8 0.1 1.2 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KFL62467.1 - 3.4e-14 52.9 0.0 5.6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFL62467.1 - 1.6e-05 24.5 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFL62467.1 - 0.013 15.5 0.4 0.38 10.8 0.0 2.6 2 1 1 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 KFL62467.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Arf PF00025.21 KFL62467.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family IIGP PF05049.13 KFL62467.1 - 0.2 10.7 0.1 0.3 10.1 0.1 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Nop14 PF04147.12 KFL62467.1 - 4.1 5.5 5.5 5.4 5.1 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family MAT1 PF06391.13 KFL62468.1 - 6.9e-42 143.6 17.4 9.1e-42 143.2 17.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KFL62468.1 - 1.9e-32 110.9 8.5 3e-32 110.3 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFL62468.1 - 0.00014 21.7 5.1 0.00024 20.9 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFL62468.1 - 0.00016 21.5 3.7 0.00041 20.1 3.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFL62468.1 - 0.0014 18.4 4.1 0.0029 17.4 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFL62468.1 - 0.0019 18.5 6.2 0.0033 17.7 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KFL62468.1 - 0.012 15.4 5.1 0.069 13.0 1.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KFL62468.1 - 0.017 14.7 1.4 0.034 13.8 1.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KFL62468.1 - 0.03 14.3 7.2 0.23 11.4 7.7 2.0 1 1 1 2 2 2 0 zinc-RING finger domain DUF3797 PF12677.7 KFL62468.1 - 0.072 13.0 2.3 0.16 11.9 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_UBOX PF13445.6 KFL62468.1 - 0.39 10.8 6.8 0.78 9.8 6.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KFL62468.1 - 1.8 8.5 8.0 41 4.2 8.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 MAT1 PF06391.13 KFL62469.1 - 5.7e-42 143.9 17.4 7.5e-42 143.5 17.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KFL62469.1 - 2.9e-20 71.9 4.2 4.5e-20 71.3 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFL62469.1 - 0.00029 20.6 1.7 0.00059 19.6 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFL62469.1 - 0.006 16.4 0.9 0.01 15.6 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFL62469.1 - 0.009 15.9 2.4 0.016 15.1 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFL62469.1 - 0.022 14.4 0.3 0.035 13.7 0.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KFL62469.1 - 0.038 13.9 2.2 0.069 13.1 2.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFL62469.1 - 0.045 14.1 2.8 0.077 13.3 2.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KFL62469.1 - 0.051 13.4 2.2 0.09 12.6 2.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2582 PF10771.9 KFL62470.1 - 0.017 15.2 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) TMF_TATA_bd PF12325.8 KFL62470.1 - 0.38 11.0 5.2 0.13 12.5 0.7 2.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding TMF_TATA_bd PF12325.8 KFL62471.1 - 0.05 13.8 0.6 0.07 13.3 0.6 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PEX11 PF05648.14 KFL62472.1 - 3.6e-26 92.0 0.1 4.5e-26 91.7 0.1 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) AP3D1 PF06375.11 KFL62475.1 - 0.39 10.9 9.7 0.51 10.6 9.7 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Peptidase_S49_N PF08496.10 KFL62475.1 - 0.99 9.5 4.3 1.7 8.7 4.2 1.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SMN PF06003.12 KFL62475.1 - 1.5 8.0 5.7 2.2 7.5 5.7 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) GAGA_bind PF06217.12 KFL62475.1 - 2.7 8.2 8.1 3.4 7.9 8.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Pox_Ag35 PF03286.14 KFL62475.1 - 6.5 6.5 9.7 8.8 6.1 9.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein IATP PF04568.12 KFL62476.1 - 5.5e-14 52.4 1.8 6.2e-14 52.2 1.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Nsp1_C PF05064.13 KFL62477.1 - 6.2e-43 145.3 3.4 1.3e-42 144.3 3.4 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KFL62477.1 - 8.4e-05 23.3 71.0 0.00035 21.4 31.1 6.5 1 1 3 4 4 3 3 Nucleoporin FG repeat region HIP1_clath_bdg PF16515.5 KFL62477.1 - 0.06 14.0 10.4 1.4 9.6 6.0 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_13 PF13166.6 KFL62477.1 - 0.16 10.6 2.5 0.24 10.0 2.5 1.2 1 0 0 1 1 1 0 AAA domain DUF2935 PF11155.8 KFL62477.1 - 0.31 11.4 0.7 2.3 8.5 0.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Baculo_PEP_C PF04513.12 KFL62477.1 - 0.46 10.5 2.2 0.82 9.7 1.1 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 KFL62477.1 - 0.53 9.6 7.1 0.33 10.3 5.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Laminin_II PF06009.12 KFL62477.1 - 0.86 9.6 6.1 3.3 7.7 1.7 2.2 1 1 1 2 2 2 0 Laminin Domain II IFT57 PF10498.9 KFL62477.1 - 0.88 8.5 8.6 0.13 11.2 3.9 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 CK2S PF15011.6 KFL62477.1 - 0.88 9.4 5.4 1.7 8.5 3.4 2.1 2 0 0 2 2 2 0 Casein Kinase 2 substrate FlaC_arch PF05377.11 KFL62477.1 - 1.3 9.5 7.6 0.88 10.0 0.4 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 KFL62477.1 - 2 8.6 12.7 0.41 10.9 6.7 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 KFL62477.1 - 2.4 8.6 12.5 0.19 12.1 6.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Med21 PF11221.8 KFL62477.1 - 2.9 8.1 15.1 1.1e+02 3.0 15.0 3.0 1 1 0 1 1 1 0 Subunit 21 of Mediator complex OmpH PF03938.14 KFL62477.1 - 4.1 7.7 12.4 23 5.3 0.1 2.3 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) V-SNARE PF05008.15 KFL62477.1 - 6 7.3 9.8 1.1 9.7 0.8 3.0 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus CREPT PF16566.5 KFL62477.1 - 8.3 6.6 6.3 0.96 9.6 1.7 1.7 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Nsp1_C PF05064.13 KFL62478.1 - 7.6e-43 145.0 3.4 1.2e-42 144.4 3.4 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KFL62478.1 - 0.00028 21.7 30.9 0.00028 21.7 30.9 6.5 1 1 1 2 2 1 1 Nucleoporin FG repeat region ATG16 PF08614.11 KFL62478.1 - 0.047 13.9 5.4 0.15 12.2 5.4 1.9 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 KFL62478.1 - 0.13 12.7 6.2 0.18 12.2 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) IFT57 PF10498.9 KFL62478.1 - 0.16 10.9 4.7 0.22 10.4 4.7 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FlaC_arch PF05377.11 KFL62478.1 - 0.53 10.7 3.3 0.82 10.1 0.4 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HIP1_clath_bdg PF16515.5 KFL62478.1 - 0.76 10.4 6.0 1.2 9.7 6.0 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V-SNARE PF05008.15 KFL62478.1 - 0.83 10.1 3.5 0.93 9.9 0.4 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Spc7 PF08317.11 KFL62478.1 - 1.2 8.0 7.5 1.7 7.5 7.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 KFL62478.1 - 1.2 8.9 5.5 1.8 8.4 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.12 KFL62478.1 - 6.8 6.8 12.4 9.8 6.3 12.4 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein JAB PF01398.21 KFL62479.1 - 1.2e-27 96.3 0.0 2.9e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFL62479.1 - 4.2e-12 46.5 0.7 6.3e-12 45.9 0.7 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KFL62479.1 - 3.7e-07 29.9 0.0 3.2e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 KFL62480.1 - 1.4e-27 96.0 0.0 2.8e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFL62480.1 - 6.8e-12 45.8 0.0 1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KFL62480.1 - 1.8e-06 27.7 0.0 3.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Pec_lyase_N PF04431.13 KFL62481.1 - 0.17 12.1 0.1 0.32 11.3 0.1 1.4 1 0 0 1 1 1 0 Pectate lyase, N terminus Med3 PF11593.8 KFL62481.1 - 1.8 7.7 5.2 2 7.5 5.2 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Fungal_trans PF04082.18 KFL62482.1 - 5.7e-09 35.4 0.5 1.2e-08 34.3 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MPS2 PF17060.5 KFL62482.1 - 0.18 11.0 0.1 0.3 10.3 0.1 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Pkinase PF00069.25 KFL62484.1 - 4e-59 200.1 0.0 6.4e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62484.1 - 4.4e-25 88.4 0.0 1e-24 87.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFL62484.1 - 0.00074 18.9 0.1 0.47 9.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFL62484.1 - 0.068 11.9 0.2 0.18 10.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 KFL62485.1 - 7.9e-27 94.3 0.0 1.1e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62485.1 - 3.6e-06 26.5 0.0 5.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S21e PF01249.18 KFL62486.1 - 5.3e-42 141.8 0.0 5.9e-42 141.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e HPIH PF13323.6 KFL62488.1 - 7.8e-47 159.0 0.0 9.7e-47 158.7 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain with HPIH motif HMG-CoA_red PF00368.18 KFL62489.1 - 1.4e-134 448.7 8.9 1.9e-134 448.3 8.9 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 KFL62489.1 - 1.7e-10 41.0 0.4 7.9e-10 38.8 0.4 2.0 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KFL62489.1 - 0.0093 14.1 0.0 0.014 13.5 0.0 1.2 1 0 0 1 1 1 1 Patched family DUF498 PF04430.14 KFL62490.1 - 2e-21 76.1 0.1 2.3e-21 75.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) APG6_N PF17675.1 KFL62492.1 - 0.0078 16.7 9.4 0.0078 16.7 9.4 3.8 2 1 2 4 4 4 1 Apg6 coiled-coil region VGPC1_C PF16799.5 KFL62492.1 - 0.059 13.3 3.1 0.25 11.4 3.1 2.1 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Nup88 PF10168.9 KFL62492.1 - 0.47 8.2 17.8 0.81 7.4 17.8 1.3 1 0 0 1 1 1 0 Nuclear pore component Piezo_RRas_bdg PF12166.8 KFL62492.1 - 1.5 8.0 7.7 1.1 8.4 5.6 1.4 1 1 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain GIT1_C PF12205.8 KFL62492.1 - 1.7 8.8 10.0 0.11 12.6 0.4 3.3 2 1 2 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term EzrA PF06160.12 KFL62492.1 - 2.8 6.0 31.0 0.36 9.0 15.0 2.9 2 2 0 3 3 3 0 Septation ring formation regulator, EzrA Fmp27_WPPW PF10359.9 KFL62492.1 - 4.8 5.9 23.7 0.45 9.3 9.2 2.4 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain VGPC1_C PF16799.5 KFL62493.1 - 0.054 13.5 3.1 0.19 11.8 3.1 1.9 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 EzrA PF06160.12 KFL62493.1 - 0.12 10.5 26.5 0.23 9.6 14.9 2.3 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA Nup88 PF10168.9 KFL62493.1 - 0.32 8.8 17.8 0.51 8.1 17.8 1.2 1 0 0 1 1 1 0 Nuclear pore component APG6_N PF17675.1 KFL62493.1 - 0.55 10.8 46.3 6.2e+02 0.9 7.0 3.2 1 1 1 2 2 1 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 KFL62493.1 - 1.1 9.9 37.0 0.7 10.5 21.1 3.0 2 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_TATA_bd PF12325.8 KFL62493.1 - 1.1 9.5 37.4 0.39 10.9 6.0 4.3 1 1 3 4 4 3 0 TATA element modulatory factor 1 TATA binding Piezo_RRas_bdg PF12166.8 KFL62493.1 - 1.5 8.0 8.3 2.1 7.5 7.6 1.4 1 1 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Rho_Binding PF08912.11 KFL62493.1 - 2.2 9.1 29.9 0.36 11.7 1.2 4.8 3 1 1 4 4 4 0 Rho Binding Fib_alpha PF08702.10 KFL62493.1 - 3.2 7.9 26.2 0.91 9.7 11.8 3.7 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Fmp27_WPPW PF10359.9 KFL62493.1 - 3.3 6.5 23.8 0.31 9.9 9.2 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.9 KFL62493.1 - 8.6 5.3 27.1 1.1 8.3 2.9 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Seryl_tRNA_N PF02403.22 KFL62493.1 - 8.9 6.6 26.4 16 5.7 6.9 3.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Oxysterol_BP PF01237.18 KFL62495.1 - 1.2e-29 103.3 0.9 2.4e-19 69.4 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein Oxysterol_BP PF01237.18 KFL62496.1 - 3.3e-49 167.7 0.0 4e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF1805 PF08827.11 KFL62497.1 - 0.18 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) RRM_1 PF00076.22 KFL62498.1 - 0.0046 16.7 0.0 0.018 14.8 0.0 2.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFL62498.1 - 0.061 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 RRM_1 PF00076.22 KFL62499.1 - 0.051 13.4 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.9 KFL62499.1 - 0.75 9.4 14.0 1.2 8.7 14.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRM_1 PF00076.22 KFL62500.1 - 0.00024 20.8 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 KFL62500.1 - 0.44 10.5 9.8 0.091 12.7 4.8 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Amidase PF01425.21 KFL62501.1 - 1.7e-65 221.7 0.0 3e-65 221.0 0.0 1.3 1 1 0 1 1 1 1 Amidase zf-RING_2 PF13639.6 KFL62502.1 - 1.3e-08 35.0 4.2 1.3e-08 35.0 4.2 2.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFL62502.1 - 8e-07 28.8 11.0 9.6e-07 28.5 3.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFL62502.1 - 8.9e-06 25.3 9.5 3.1e-05 23.6 4.8 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KFL62502.1 - 0.00043 20.1 3.6 0.00043 20.1 3.6 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFL62502.1 - 0.00058 20.1 5.9 0.00058 20.1 5.9 2.9 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFL62502.1 - 0.0093 16.0 12.6 0.0093 16.0 3.4 2.8 3 0 0 3 3 2 1 RING-type zinc-finger Zn-C2H2_12 PF18112.1 KFL62502.1 - 0.034 14.6 0.1 0.034 14.6 0.1 2.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-RING-like PF08746.11 KFL62502.1 - 0.058 13.7 2.5 0.058 13.7 2.5 2.4 2 1 0 2 2 2 0 RING-like domain AgrD PF05931.11 KFL62502.1 - 0.16 12.0 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Staphylococcal AgrD protein zf-ANAPC11 PF12861.7 KFL62502.1 - 0.73 9.9 7.7 3.1 7.9 3.3 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KFL62502.1 - 0.74 9.8 13.3 1.1 9.3 4.4 2.7 3 0 0 3 3 3 0 zinc-RING finger domain RecR PF02132.15 KFL62502.1 - 0.91 9.1 10.6 0.68 9.6 4.3 2.9 2 1 1 3 3 3 0 RecR protein zf-C3HC4_3 PF13920.6 KFL62502.1 - 1.6 8.7 11.4 5.3 7.0 4.1 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KFL62502.1 - 4.7 7.5 10.8 1.2 9.3 5.8 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain FYVE PF01363.21 KFL62503.1 - 4.5e-19 68.4 5.6 9.4e-19 67.3 5.6 1.5 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KFL62503.1 - 0.042 14.1 0.5 0.074 13.3 0.5 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 KFL62503.1 - 0.17 12.2 3.7 0.41 11.0 3.7 1.7 1 0 0 1 1 1 0 C1 domain C12orf66_like PF09404.10 KFL62503.1 - 0.22 10.3 0.7 0.31 9.8 0.7 1.1 1 0 0 1 1 1 0 KICSTOR complex C12orf66 like SUIM_assoc PF16619.5 KFL62504.1 - 3.8 7.6 26.2 1.1 9.3 3.3 3.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ABC2_membrane PF01061.24 KFL62505.1 - 1.6e-30 106.1 28.8 2.1e-30 105.7 28.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KFL62505.1 - 0.00016 20.9 20.7 0.00018 20.7 20.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein PIG-P PF08510.12 KFL62505.1 - 4.7 7.1 15.0 0.12 12.2 1.9 2.6 1 1 1 2 2 2 0 PIG-P ABC_tran PF00005.27 KFL62506.1 - 2.8e-26 92.7 0.1 3.9e-26 92.2 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFL62506.1 - 1.7e-08 34.6 0.2 0.0015 18.4 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFL62506.1 - 3.4e-06 27.1 0.2 1.6e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KFL62506.1 - 8.7e-05 22.1 0.1 0.00023 20.7 0.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 KFL62506.1 - 0.0001 21.1 0.4 0.0039 15.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFL62506.1 - 0.0002 21.8 0.0 0.00025 21.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KFL62506.1 - 0.00069 19.2 0.0 0.0015 18.2 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 KFL62506.1 - 0.00084 19.8 0.1 0.025 15.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KFL62506.1 - 0.0017 17.5 0.0 0.0032 16.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KFL62506.1 - 0.0022 17.8 0.0 0.005 16.6 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KFL62506.1 - 0.0024 18.2 0.1 0.0055 17.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFL62506.1 - 0.0032 17.2 0.1 0.0066 16.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 KFL62506.1 - 0.0045 16.6 0.0 0.0091 15.6 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KFL62506.1 - 0.0054 16.5 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KFL62506.1 - 0.0054 16.7 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 KFL62506.1 - 0.006 17.1 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFL62506.1 - 0.0086 16.3 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFL62506.1 - 0.015 15.5 0.0 0.031 14.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 KFL62506.1 - 0.024 14.6 0.1 0.039 13.9 0.0 1.5 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KFL62506.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KFL62506.1 - 0.026 14.1 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KFL62506.1 - 0.044 14.3 0.2 0.11 13.0 0.1 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFL62506.1 - 0.045 14.2 0.0 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 KFL62506.1 - 0.062 13.3 0.1 0.26 11.3 0.0 2.1 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KFL62506.1 - 0.064 13.0 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 KFL62506.1 - 0.071 13.5 0.1 0.13 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KFL62506.1 - 0.094 12.5 0.1 0.2 11.4 0.1 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KFL62506.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFL62506.1 - 0.12 12.5 0.5 0.25 11.4 0.2 1.7 2 0 0 2 2 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 KFL62506.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 KFL62506.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Septin PF00735.18 KFL62506.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Septin tRNA-synt_2 PF00152.20 KFL62507.1 - 1.4e-42 145.9 0.0 1.7e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) ABC_membrane PF00664.23 KFL62509.1 - 8.9e-08 32.1 4.2 1.2e-07 31.7 4.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFL62509.1 - 0.0098 16.4 0.0 0.036 14.6 0.0 1.7 1 1 1 2 2 2 1 ABC transporter UL45 PF05473.12 KFL62509.1 - 0.59 9.7 2.2 0.93 9.1 2.2 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like ABC_tran PF00005.27 KFL62510.1 - 6.3e-06 26.7 0.0 1.4e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFL62510.1 - 0.049 13.0 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SelP_C PF04593.14 KFL62511.1 - 0.01 15.8 0.2 0.012 15.6 0.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, C terminal region ERbeta_N PF12497.8 KFL62511.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Estrogen receptor beta Peptidase_M28 PF04389.17 KFL62512.1 - 7.2e-30 104.2 0.0 1.3e-29 103.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 PIG-U PF06728.13 KFL62514.1 - 1.9e-83 280.6 28.0 2.4e-83 280.3 28.0 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 KFL62514.1 - 0.0028 17.6 0.4 0.0028 17.6 0.4 2.0 1 1 0 2 2 2 1 Mannosyltransferase (PIG-M) Abhydrolase_6 PF12697.7 KFL62515.1 - 3.2e-12 47.5 0.2 4.9e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFL62515.1 - 2.1e-08 33.7 0.0 4.4e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFL62515.1 - 1.2e-07 31.6 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFL62515.1 - 0.00012 22.1 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.12 KFL62515.1 - 0.00041 19.4 0.0 0.00063 18.8 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 KFL62515.1 - 0.033 13.7 0.0 0.086 12.3 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Syja_N PF02383.18 KFL62516.1 - 2.2e-86 290.1 0.0 2.8e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Syja_N PF02383.18 KFL62517.1 - 8.3e-83 278.3 0.0 1e-82 278.0 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain FUN14 PF04930.15 KFL62517.1 - 0.025 15.0 0.1 1.1 9.7 0.0 2.9 3 0 0 3 3 3 0 FUN14 family DUF3712 PF12505.8 KFL62518.1 - 2.2e-30 105.5 2.1 5e-30 104.3 1.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Wzy_C PF04932.15 KFL62518.1 - 0.035 13.7 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 O-Antigen ligase DUF4307 PF14155.6 KFL62518.1 - 0.035 13.9 0.5 0.06 13.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) ASFV_J13L PF05568.11 KFL62518.1 - 0.093 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF1776 PF08643.10 KFL62519.1 - 1.5e-84 283.9 0.0 1.8e-84 283.6 0.0 1.0 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KFL62519.1 - 0.018 14.5 0.0 0.059 12.8 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase AMP-binding PF00501.28 KFL62522.1 - 2.2e-37 128.7 0.0 2.4e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KFL62524.1 - 8.1e-12 45.3 0.0 1.8e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site RL11D PF11088.8 KFL62524.1 - 0.097 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Condensation PF00668.20 KFL62525.1 - 0.027 13.1 0.3 0.98 8.0 0.1 2.0 1 1 1 2 2 2 0 Condensation domain Condensation PF00668.20 KFL62526.1 - 1e-12 47.5 0.0 2.1e-05 23.4 0.0 3.0 2 1 1 3 3 3 3 Condensation domain P34-Arc PF04045.14 KFL62527.1 - 4.5e-84 281.9 0.4 5.1e-84 281.7 0.4 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 KFL62527.1 - 0.068 12.8 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) DUF2158 PF09926.9 KFL62527.1 - 0.094 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) Hemerythrin PF01814.23 KFL62527.1 - 0.17 12.5 1.1 6.9 7.3 0.2 2.2 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain P34-Arc PF04045.14 KFL62528.1 - 1.1e-68 231.6 0.1 1.2e-68 231.4 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF2158 PF09926.9 KFL62528.1 - 0.071 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) Fcf1 PF04900.12 KFL62529.1 - 1.9e-11 44.2 0.1 5.2e-11 42.8 0.1 1.7 1 1 0 1 1 1 1 Fcf1 Sigma_reg_N PF13800.6 KFL62529.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal SWI-SNF_Ssr4 PF08549.10 KFL62530.1 - 0.03 13.0 4.9 0.032 12.9 4.9 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) GET2 PF08690.10 KFL62530.1 - 4.1 7.0 6.2 5.7 6.5 6.2 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 RR_TM4-6 PF06459.12 KFL62530.1 - 6 6.6 9.3 7.7 6.3 9.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.11 KFL62532.1 - 5.8e-136 454.3 1.7 5.8e-136 454.3 1.7 1.9 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 PknG_rubred PF16919.5 KFL62534.1 - 0.41 10.8 2.5 7.6 6.7 2.5 2.0 1 1 0 1 1 1 0 Protein kinase G rubredoxin domain Esterase PF00756.20 KFL62536.1 - 9.7e-30 104.0 0.0 1.2e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KFL62536.1 - 0.00017 21.1 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFL62536.1 - 0.00069 19.0 0.0 0.00092 18.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KFL62536.1 - 0.0093 14.9 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.13 KFL62536.1 - 0.014 15.1 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 KFL62536.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Tannase PF07519.11 KFL62536.1 - 0.023 13.6 0.2 0.03 13.2 0.2 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase Abhydrolase_2 PF02230.16 KFL62536.1 - 0.042 13.7 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 KFL62536.1 - 0.045 12.4 0.0 0.22 10.1 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.18 KFL62538.1 - 1.5e-18 66.8 0.1 2.1e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ZipA_C PF04354.13 KFL62538.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain Terpene_synth_C PF03936.16 KFL62541.1 - 0.02 14.2 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Rsbr_N PF08678.10 KFL62541.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Rsbr N terminal Ferric_reduct PF01794.19 KFL62544.1 - 2.9e-26 92.0 9.1 2.9e-26 92.0 9.1 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFL62544.1 - 6.9e-16 58.7 0.1 2e-13 50.7 0.0 2.7 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFL62544.1 - 5.4e-11 42.6 0.0 3.9e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KFL62544.1 - 0.17 12.5 0.0 0.79 10.4 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain adh_short_C2 PF13561.6 KFL62545.1 - 1.2e-30 106.9 0.1 1.2e-30 106.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFL62545.1 - 2e-16 60.1 0.0 2.6e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Glyco_transf_5 PF08323.11 KFL62545.1 - 0.006 16.3 0.0 0.006 16.3 0.0 1.1 1 0 0 1 1 1 1 Starch synthase catalytic domain adh_short PF00106.25 KFL62546.1 - 9.3e-22 77.4 0.4 1.1e-21 77.2 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFL62546.1 - 9.2e-13 48.3 0.6 1.2e-12 48.0 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFL62546.1 - 3e-11 43.6 0.6 3.6e-11 43.3 0.6 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFL62546.1 - 1.5e-05 24.6 0.1 1.7e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFL62546.1 - 3.6e-05 23.3 0.1 4.5e-05 23.0 0.1 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KFL62546.1 - 0.00047 19.5 0.2 0.00072 18.9 0.1 1.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 KFL62546.1 - 0.033 13.8 0.2 0.056 13.1 0.2 1.4 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KFL62546.1 - 0.065 12.6 0.1 0.074 12.4 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.19 KFL62546.1 - 0.067 11.9 0.0 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Eno-Rase_NADH_b PF12242.8 KFL62546.1 - 0.093 12.5 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LSM PF01423.22 KFL62550.1 - 1.3e-16 60.0 1.0 1.7e-16 59.7 1.0 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KFL62550.1 - 0.0096 16.0 0.2 0.014 15.5 0.2 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain SM-ATX PF14438.6 KFL62550.1 - 0.13 12.4 0.2 0.2 11.8 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Pan3_PK PF18101.1 KFL62551.1 - 1.6e-62 209.6 0.4 2.5e-62 208.9 0.4 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KFL62551.1 - 8.7e-06 25.3 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62551.1 - 0.12 11.6 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pan3_PK PF18101.1 KFL62552.1 - 1.6e-62 209.6 0.4 2.5e-62 208.9 0.4 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KFL62552.1 - 8.7e-06 25.3 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62552.1 - 0.12 11.6 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pan3_PK PF18101.1 KFL62553.1 - 1.2e-62 209.9 0.4 2.1e-62 209.2 0.4 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KFL62553.1 - 7e-06 25.6 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62553.1 - 0.1 11.9 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pan3_PK PF18101.1 KFL62554.1 - 1.2e-62 209.9 0.4 2.1e-62 209.2 0.4 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KFL62554.1 - 7e-06 25.6 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62554.1 - 0.1 11.9 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pan3_PK PF18101.1 KFL62555.1 - 1.2e-62 209.9 0.4 2.1e-62 209.2 0.4 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KFL62555.1 - 7e-06 25.6 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62555.1 - 0.1 11.9 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pan3_PK PF18101.1 KFL62556.1 - 1.2e-62 209.9 0.4 2.1e-62 209.2 0.4 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KFL62556.1 - 7e-06 25.6 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62556.1 - 0.1 11.9 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Fibrillarin PF01269.17 KFL62557.1 - 2.1e-104 347.6 0.0 2.5e-104 347.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KFL62557.1 - 5.5e-06 26.2 0.0 8.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 KFL62557.1 - 0.026 14.1 0.0 0.055 13.1 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 KFL62557.1 - 0.04 13.7 0.1 0.065 13.0 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Peptidase_M16_C PF05193.21 KFL62558.1 - 7.3e-39 133.7 0.0 1.4e-38 132.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFL62558.1 - 1.6e-27 96.3 0.0 7e-27 94.2 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16 PF00675.20 KFL62559.1 - 4.4e-55 185.8 0.0 1.6e-54 184.0 0.1 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFL62559.1 - 4.2e-28 98.6 0.0 1.2e-26 93.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain MFS_1 PF07690.16 KFL62560.1 - 2e-19 69.7 11.5 2.5e-19 69.5 11.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFL62560.1 - 2.2e-09 36.7 0.9 3.3e-09 36.1 0.6 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KFL62560.1 - 0.00022 20.7 1.6 0.00027 20.3 1.6 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Vps55 PF04133.14 KFL62560.1 - 0.0019 18.1 1.3 0.0036 17.3 1.3 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 55 TRI12 PF06609.13 KFL62560.1 - 0.0029 16.1 0.7 0.0043 15.5 0.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.18 KFL62560.1 - 0.069 11.9 0.6 0.08 11.7 0.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier MFS_1 PF07690.16 KFL62561.1 - 6.6e-06 25.3 5.0 6.6e-06 25.3 5.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FA_desaturase PF00487.24 KFL62561.1 - 1.5 8.6 8.6 0.63 9.8 5.5 1.7 1 1 1 2 2 2 0 Fatty acid desaturase Fungal_trans PF04082.18 KFL62562.1 - 4.5e-21 75.1 0.1 2.8e-19 69.2 0.0 2.8 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KFL62563.1 - 1.7e-08 34.4 8.3 2.8e-08 33.7 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.9 KFL62563.1 - 0.039 14.1 0.3 0.066 13.3 0.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) HD-ZIP_N PF04618.12 KFL62563.1 - 0.17 12.4 1.0 0.3 11.6 1.0 1.6 1 1 0 1 1 1 0 HD-ZIP protein N terminus tRNA-synt_1c PF00749.21 KFL62564.1 - 7.2e-98 327.3 0.0 9.9e-98 326.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFL62564.1 - 4.1e-18 65.9 0.0 1.2e-17 64.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF3408 PF11888.8 KFL62564.1 - 4.7 7.3 7.5 11 6.2 7.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) tRNA-synt_1c PF00749.21 KFL62565.1 - 5.5e-98 327.7 0.0 7.6e-98 327.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFL62565.1 - 0.0036 17.2 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF3408 PF11888.8 KFL62565.1 - 4.4 7.4 7.5 9.6 6.3 7.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Filament_head PF04732.14 KFL62566.1 - 2.3 9.2 7.9 34 5.4 4.6 2.3 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region N2227 PF07942.12 KFL62569.1 - 4.3e-73 245.8 0.0 8.8e-73 244.8 0.0 1.5 1 1 0 1 1 1 1 N2227-like protein PepSY_2 PF13670.6 KFL62569.1 - 0.25 11.3 2.0 1.8 8.6 0.0 2.7 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain SelP_N PF04592.14 KFL62569.1 - 0.81 9.0 4.8 1.2 8.4 4.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HSP70 PF00012.20 KFL62570.1 - 2.6e-10 39.1 0.1 6.9e-09 34.4 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KFL62570.1 - 0.12 11.2 0.0 0.34 9.7 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.20 KFL62571.1 - 3.5e-07 28.8 0.1 1e-05 23.9 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KFL62571.1 - 0.13 11.1 0.1 0.28 9.9 0.0 1.5 2 0 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.20 KFL62572.1 - 3.5e-07 28.8 0.1 1e-05 23.9 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KFL62572.1 - 0.13 11.1 0.1 0.28 9.9 0.0 1.5 2 0 0 2 2 2 0 MreB/Mbl protein DUF3445 PF11927.8 KFL62573.1 - 1.6e-63 214.4 0.0 2e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Lipase_GDSL_3 PF14606.6 KFL62573.1 - 0.15 12.1 0.0 0.46 10.6 0.0 1.7 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Smim3 PF17307.2 KFL62574.1 - 0.056 12.9 1.3 0.1 12.1 1.3 1.4 1 0 0 1 1 1 0 Small integral membrane protein 3 AMP-binding PF00501.28 KFL62575.1 - 3e-58 197.4 0.1 9.5e-37 126.6 0.0 3.9 2 2 0 2 2 2 2 AMP-binding enzyme AMP-binding PF00501.28 KFL62576.1 - 1.8e-53 181.6 0.0 8.3e-37 126.8 0.0 3.1 2 1 0 2 2 2 2 AMP-binding enzyme Peptidase_M24 PF00557.24 KFL62579.1 - 1.6e-53 181.5 0.0 1.9e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 NAD_binding_8 PF13450.6 KFL62579.1 - 0.089 13.0 0.1 8.2 6.7 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DnaJ PF00226.31 KFL62580.1 - 2.5e-16 59.5 0.6 6.4e-16 58.2 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KFL62580.1 - 5.9e-14 51.8 0.0 5.8e-13 48.6 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 KFL62581.1 - 2.1e-16 59.8 0.6 5.3e-16 58.5 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KFL62581.1 - 3.9e-14 52.4 0.0 4.4e-13 49.0 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 KFL62582.1 - 1.8e-16 60.0 0.6 4.7e-16 58.7 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KFL62582.1 - 2.9e-14 52.9 0.0 3.2e-13 49.4 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain Sec63 PF02889.16 KFL62583.1 - 2.8e-14 52.9 0.0 3e-13 49.5 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 KFL62583.1 - 0.018 15.2 0.1 0.049 13.8 0.1 1.7 1 0 0 1 1 1 0 DnaJ domain DTHCT PF08070.11 KFL62583.1 - 4.7 8.0 12.0 7.8 7.3 5.7 2.5 2 0 0 2 2 2 0 DTHCT (NUC029) region Senescence PF06911.12 KFL62585.1 - 5e-55 186.7 1.3 7.9e-55 186.0 1.3 1.3 1 0 0 1 1 1 1 Senescence-associated protein RCR PF12273.8 KFL62585.1 - 2.9 8.6 10.5 3 8.5 6.8 2.6 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Bap31 PF05529.12 KFL62586.1 - 2.4e-48 163.4 7.1 3.1e-48 163.1 7.1 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KFL62586.1 - 7.2e-16 57.9 3.8 1.1e-15 57.3 3.8 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Atg14 PF10186.9 KFL62586.1 - 0.03 13.4 1.3 0.039 13.1 1.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 KFL62586.1 - 0.032 14.4 0.5 0.057 13.6 0.4 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 KFL62586.1 - 0.04 13.7 2.6 0.078 12.8 0.3 2.5 2 1 0 2 2 2 0 Septum formation initiator Cep57_MT_bd PF06657.13 KFL62586.1 - 0.075 13.5 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF4349 PF14257.6 KFL62586.1 - 0.12 11.8 0.2 0.12 11.8 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Bap31 PF05529.12 KFL62587.1 - 5.2e-41 139.7 2.6 6.7e-41 139.3 2.6 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KFL62587.1 - 6.3e-16 58.1 3.8 9.6e-16 57.5 3.8 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Atg14 PF10186.9 KFL62587.1 - 0.025 13.7 1.2 0.03 13.4 1.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 KFL62587.1 - 0.027 14.7 0.5 0.049 13.8 0.4 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 KFL62587.1 - 0.039 13.7 2.6 0.069 12.9 0.3 2.4 2 1 0 2 2 2 0 Septum formation initiator DUF4349 PF14257.6 KFL62587.1 - 0.063 12.7 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Cep57_MT_bd PF06657.13 KFL62587.1 - 0.065 13.7 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 PAP_central PF04928.17 KFL62590.1 - 0.076 12.0 0.0 0.098 11.6 0.0 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain Mei5 PF10376.9 KFL62591.1 - 6.2e-05 23.0 8.0 0.00074 19.4 0.5 2.4 2 1 0 2 2 2 2 Double-strand recombination repair protein Drc1-Sld2 PF11719.8 KFL62591.1 - 0.36 10.3 9.1 0.49 9.9 9.1 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nucleo_P87 PF07267.11 KFL62591.1 - 2.7 6.8 10.6 1.9 7.3 9.4 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SlyX PF04102.12 KFL62591.1 - 3.3 8.4 9.5 7.3 7.3 0.7 2.5 2 0 0 2 2 2 0 SlyX NOA36 PF06524.12 KFL62591.1 - 9.4 5.4 9.9 15 4.8 9.9 1.3 1 0 0 1 1 1 0 NOA36 protein Aldedh PF00171.22 KFL62592.1 - 8.6e-121 403.6 0.1 1e-120 403.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFL62592.1 - 0.098 12.1 0.2 0.2 11.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Aldedh PF00171.22 KFL62593.1 - 7.6e-111 370.9 0.1 9.6e-111 370.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFL62593.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) HMGL-like PF00682.19 KFL62596.1 - 9.4e-51 172.9 0.2 1.4e-50 172.3 0.2 1.3 1 0 0 1 1 1 1 HMGL-like HMGL-like PF00682.19 KFL62597.1 - 9.4e-51 172.9 0.2 1.4e-50 172.3 0.2 1.3 1 0 0 1 1 1 1 HMGL-like HMGL-like PF00682.19 KFL62598.1 - 9.4e-51 172.9 0.2 1.4e-50 172.3 0.2 1.3 1 0 0 1 1 1 1 HMGL-like HMGL-like PF00682.19 KFL62599.1 - 1e-42 146.5 0.1 1.5e-42 146.0 0.1 1.3 1 0 0 1 1 1 1 HMGL-like Como_LCP PF02247.16 KFL62599.1 - 0.17 10.5 0.2 0.26 9.8 0.2 1.2 1 0 0 1 1 1 0 Large coat protein HMGL-like PF00682.19 KFL62600.1 - 1e-42 146.5 0.1 1.5e-42 146.0 0.1 1.3 1 0 0 1 1 1 1 HMGL-like Como_LCP PF02247.16 KFL62600.1 - 0.17 10.5 0.2 0.26 9.8 0.2 1.2 1 0 0 1 1 1 0 Large coat protein HMGL-like PF00682.19 KFL62601.1 - 1e-42 146.5 0.1 1.5e-42 146.0 0.1 1.3 1 0 0 1 1 1 1 HMGL-like Como_LCP PF02247.16 KFL62601.1 - 0.17 10.5 0.2 0.26 9.8 0.2 1.2 1 0 0 1 1 1 0 Large coat protein APH PF01636.23 KFL62603.1 - 7.5e-09 35.9 0.0 8e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFL62603.1 - 2.9e-05 23.8 0.0 3.3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KFL62603.1 - 0.0028 16.6 0.0 0.0038 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KFL62603.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Bromodomain PF00439.25 KFL62607.1 - 1.2e-38 131.0 1.0 1.5e-19 69.8 0.5 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFL62607.1 - 3.7e-18 65.5 0.2 8.8e-18 64.2 0.2 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF3573 PF12097.8 KFL62607.1 - 0.22 10.3 2.4 0.48 9.2 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Bromodomain PF00439.25 KFL62608.1 - 1.2e-38 131.0 1.0 1.5e-19 69.8 0.5 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFL62608.1 - 3.7e-18 65.5 0.2 8.8e-18 64.2 0.2 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF3573 PF12097.8 KFL62608.1 - 0.22 10.3 2.4 0.48 9.2 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Bromodomain PF00439.25 KFL62609.1 - 1.2e-38 131.0 1.0 1.5e-19 69.9 0.5 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFL62609.1 - 3.6e-18 65.5 0.2 8.6e-18 64.3 0.2 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF3573 PF12097.8 KFL62609.1 - 0.22 10.3 2.4 0.47 9.2 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) APH PF01636.23 KFL62610.1 - 9e-16 58.5 0.1 1.3e-15 58.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFL62610.1 - 2.2e-05 24.1 0.0 4.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KFL62610.1 - 0.0029 17.0 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF1679 PF07914.11 KFL62610.1 - 0.0035 16.3 0.2 0.48 9.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 KFL62610.1 - 0.033 13.4 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Pkinase_Tyr PF07714.17 KFL62610.1 - 0.17 11.1 0.1 1.2 8.3 0.1 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Glyco_hydro_56 PF01630.18 KFL62610.1 - 0.23 10.5 1.2 10 5.0 0.0 2.6 1 1 2 3 3 3 0 Hyaluronidase APH PF01636.23 KFL62611.1 - 3.3e-09 37.0 1.5 1.6e-08 34.7 0.9 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFL62611.1 - 2e-05 24.3 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF2407_C PF13373.6 KFL62613.1 - 1.5e-41 141.8 0.1 2.3e-41 141.2 0.1 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KFL62613.1 - 1e-38 132.1 0.0 2e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Fe-S_biosyn PF01521.20 KFL62613.1 - 1e-19 70.8 0.0 2.5e-19 69.5 0.0 1.7 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis ubiquitin PF00240.23 KFL62613.1 - 0.034 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Rad60-SLD_2 PF13881.6 KFL62613.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Glyco_transf_34 PF05637.12 KFL62614.1 - 6e-42 144.0 0.0 7.4e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family An_peroxidase PF03098.15 KFL62616.1 - 4.9e-19 68.3 0.0 1.1e-18 67.1 0.0 1.6 2 0 0 2 2 2 1 Animal haem peroxidase Pribosyl_synth PF14572.6 KFL62617.1 - 4e-44 150.8 1.0 3.5e-37 128.2 0.4 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFL62617.1 - 5.9e-38 129.4 0.3 2.5e-35 120.9 0.1 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFL62617.1 - 4.4e-18 65.3 0.3 7.4e-18 64.6 0.3 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFL62617.1 - 0.002 17.6 0.1 0.0032 16.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase NAD_binding_4 PF07993.12 KFL62619.1 - 8.2e-72 241.5 0.0 1.2e-71 240.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KFL62619.1 - 2.7e-70 237.1 0.0 4.1e-70 236.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KFL62619.1 - 6e-10 39.0 0.0 1.5e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 KFL62619.1 - 2.1e-09 36.6 0.2 1.6e-08 33.7 0.2 2.1 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KFL62619.1 - 3e-09 37.1 0.0 7.3e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KFL62619.1 - 0.0006 18.9 0.0 0.0022 17.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KFL62619.1 - 0.00088 20.2 0.0 0.0035 18.3 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 KFL62619.1 - 0.0013 18.6 0.0 0.031 14.1 0.0 2.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFL62619.1 - 0.017 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFL62619.1 - 0.11 11.6 0.0 0.41 9.7 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain AMP-binding PF00501.28 KFL62620.1 - 2.3e-70 237.3 0.0 3.4e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KFL62620.1 - 2e-60 204.1 0.0 3.2e-60 203.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.20 KFL62620.1 - 1.8e-09 36.8 0.2 1.4e-08 33.9 0.2 2.2 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KFL62620.1 - 2.7e-09 37.2 0.0 6.7e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KFL62620.1 - 1.9e-08 34.0 0.0 4.8e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KFL62620.1 - 0.00093 20.1 0.0 0.0031 18.4 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 KFL62620.1 - 0.004 16.2 0.0 0.014 14.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFL62620.1 - 0.0097 15.8 0.0 0.21 11.4 0.0 2.4 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFL62620.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Aminotran_1_2 PF00155.21 KFL62621.1 - 2.8e-62 211.0 0.0 3.5e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFL62621.1 - 5.7e-05 22.5 0.0 8.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFL62621.1 - 0.0001 21.4 0.1 0.0015 17.5 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KFL62621.1 - 0.00014 20.6 0.0 0.00031 19.4 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KFL62621.1 - 0.0068 15.8 0.1 0.015 14.6 0.1 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF960 PF06124.11 KFL62622.1 - 0.019 15.6 0.1 0.024 15.3 0.1 1.1 1 0 0 1 1 1 0 Staphylococcal protein of unknown function (DUF960) Pkinase PF00069.25 KFL62623.1 - 3.6e-15 56.1 0.0 1.7e-14 53.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62623.1 - 0.0007 19.0 0.0 0.0021 17.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Reprolysin_5 PF13688.6 KFL62624.1 - 6.5e-58 196.1 6.6 6.5e-58 196.1 6.6 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFL62624.1 - 3.5e-46 157.6 1.8 8.8e-46 156.3 1.8 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFL62624.1 - 3.5e-43 147.6 1.8 7.2e-43 146.6 1.8 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KFL62624.1 - 8e-15 55.4 36.6 8e-15 55.4 36.6 4.1 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KFL62624.1 - 2.1e-11 44.4 0.2 6.9e-11 42.7 0.2 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 KFL62624.1 - 1.2e-05 25.7 1.3 1.2e-05 25.7 1.3 5.5 2 1 4 6 6 6 1 ADAM cysteine-rich domain HTH_24 PF13412.6 KFL62626.1 - 0.03 13.9 0.1 0.15 11.6 0.0 2.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Snf7 PF03357.21 KFL62627.1 - 8.4e-44 149.2 12.8 1e-43 148.9 12.8 1.1 1 0 0 1 1 1 1 Snf7 DUF3584 PF12128.8 KFL62627.1 - 0.00032 18.4 4.8 0.00044 17.9 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Atg14 PF10186.9 KFL62627.1 - 0.00077 18.6 1.6 0.00095 18.3 1.6 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 CLZ PF16526.5 KFL62627.1 - 0.0014 18.9 2.1 0.47 10.8 0.0 3.4 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 KFL62627.1 - 0.012 16.1 5.5 0.41 11.1 2.0 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.6 KFL62627.1 - 0.012 15.3 7.3 0.013 15.3 4.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HsbA PF12296.8 KFL62627.1 - 0.069 13.6 0.3 0.38 11.2 0.3 2.0 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Alpha-2-MRAP_C PF06401.11 KFL62627.1 - 0.095 12.7 2.3 0.16 11.9 1.0 1.9 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF948 PF06103.11 KFL62627.1 - 0.13 12.5 0.6 0.66 10.3 0.6 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 KFL62627.1 - 0.26 11.7 5.0 33 5.0 0.8 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 KFL62627.1 - 0.3 11.4 6.4 0.57 10.5 0.1 3.2 2 2 0 2 2 2 0 ABC transporter C-terminal domain Vps51 PF08700.11 KFL62627.1 - 1.6 8.9 6.3 2.7 8.1 0.6 3.1 2 1 1 3 3 3 0 Vps51/Vps67 DASH_Dam1 PF08653.10 KFL62627.1 - 1.8 8.4 3.6 22 5.0 0.3 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF4094 PF13334.6 KFL62627.1 - 2.8 8.4 5.0 12 6.4 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) SlyX PF04102.12 KFL62627.1 - 5.6 7.7 10.4 11 6.7 1.7 3.6 1 1 2 3 3 3 0 SlyX Pro_CA PF00484.19 KFL62631.1 - 1.1e-43 149.2 0.1 1.5e-43 148.8 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DBD_Tnp_Hermes PF10683.9 KFL62632.1 - 0.03 14.0 0.1 0.063 13.0 0.1 1.4 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain Aha1_N PF09229.11 KFL62636.1 - 2.4e-40 137.9 0.6 2.4e-40 137.9 0.6 1.5 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KFL62636.1 - 4.1e-19 69.0 0.1 7.2e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Drc1-Sld2 PF11719.8 KFL62636.1 - 0.28 10.7 2.0 0.37 10.3 2.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Aha1_N PF09229.11 KFL62637.1 - 2.4e-40 137.9 0.6 2.4e-40 137.9 0.6 1.5 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KFL62637.1 - 4.1e-19 69.0 0.1 7.2e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Drc1-Sld2 PF11719.8 KFL62637.1 - 0.28 10.7 2.0 0.37 10.3 2.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Aha1_N PF09229.11 KFL62638.1 - 2.3e-40 138.0 0.6 2.3e-40 138.0 0.6 1.5 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KFL62638.1 - 3.9e-19 69.1 0.1 7e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Drc1-Sld2 PF11719.8 KFL62638.1 - 0.27 10.7 2.0 0.36 10.3 2.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Aha1_N PF09229.11 KFL62639.1 - 2.3e-40 138.0 0.6 2.3e-40 138.0 0.6 1.5 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KFL62639.1 - 3.9e-19 69.1 0.1 7e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Drc1-Sld2 PF11719.8 KFL62639.1 - 0.27 10.7 2.0 0.36 10.3 2.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Aha1_N PF09229.11 KFL62640.1 - 2.3e-40 138.0 0.6 2.3e-40 138.0 0.6 1.5 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KFL62640.1 - 3.9e-19 69.1 0.1 7e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Drc1-Sld2 PF11719.8 KFL62640.1 - 0.27 10.7 2.0 0.36 10.3 2.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Sacchrp_dh_C PF16653.5 KFL62641.1 - 9.9e-97 324.2 0.0 1.7e-96 323.4 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Yqai PF09466.10 KFL62642.1 - 0.096 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Hypothetical protein Yqai Acyltransferase PF01553.21 KFL62643.1 - 3.3e-10 39.7 0.0 0.00023 20.8 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Vps36_ESCRT-II PF11605.8 KFL62644.1 - 0.00033 20.8 0.0 0.11 12.7 0.0 2.3 1 1 1 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 Vps36_ESCRT-II PF11605.8 KFL62645.1 - 0.00033 20.8 0.0 0.11 12.7 0.0 2.3 1 1 1 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 UCR_hinge PF02320.16 KFL62646.1 - 1.9e-26 92.0 6.9 1.9e-26 92.0 6.9 1.6 2 0 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF4211 PF13926.6 KFL62646.1 - 0.0061 16.6 0.8 0.0077 16.3 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) ORC_WH_C PF18137.1 KFL62646.1 - 0.04 14.0 1.6 0.064 13.3 1.6 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Sigma70_ner PF04546.13 KFL62646.1 - 0.12 12.3 6.2 0.11 12.3 6.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Tim54 PF11711.8 KFL62646.1 - 0.39 9.4 3.5 0.41 9.4 3.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RRN3 PF05327.11 KFL62646.1 - 1.5 7.2 4.6 1.7 7.1 4.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 KFL62646.1 - 3 7.2 11.5 3.1 7.1 11.5 1.1 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 KFL62646.1 - 3 7.0 6.9 3.3 6.8 6.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Radial_spoke PF04712.12 KFL62646.1 - 3 6.7 11.3 3.2 6.6 11.3 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Nop14 PF04147.12 KFL62646.1 - 3.1 5.9 11.9 3.1 5.9 11.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KFL62646.1 - 4 5.6 7.4 3.9 5.6 7.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KFL62646.1 - 5.3 5.0 15.1 5.5 5.0 15.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi GOLD_2 PF13897.6 KFL62646.1 - 6.4 7.3 7.7 13 6.2 7.7 1.6 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking ORC_WH_C PF18137.1 KFL62647.1 - 0.025 14.6 1.6 0.031 14.3 1.6 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF4746 PF15928.5 KFL62647.1 - 0.027 13.9 5.5 0.03 13.8 5.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_Rpc4 PF05132.14 KFL62647.1 - 0.15 12.5 1.2 0.17 12.3 1.2 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 TRAP_alpha PF03896.16 KFL62647.1 - 0.33 10.1 4.2 0.35 10.0 4.2 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.12 KFL62647.1 - 0.42 10.0 8.6 0.44 9.9 8.6 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tim54 PF11711.8 KFL62647.1 - 0.43 9.3 3.1 0.47 9.2 3.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2457 PF10446.9 KFL62647.1 - 1.2 8.2 12.5 1.3 8.1 12.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 KFL62647.1 - 1.5 8.1 9.8 1.7 7.9 9.8 1.0 1 0 0 1 1 1 0 NOA36 protein Radial_spoke PF04712.12 KFL62647.1 - 1.9 7.4 10.1 2.1 7.2 10.1 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Sigma70_ner PF04546.13 KFL62647.1 - 2 8.3 10.0 2.2 8.1 10.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.18 KFL62647.1 - 3 7.7 8.6 3.4 7.5 8.6 1.0 1 0 0 1 1 1 0 Myc amino-terminal region HSP90 PF00183.18 KFL62647.1 - 5.1 5.9 7.4 6.1 5.6 7.4 1.0 1 0 0 1 1 1 0 Hsp90 protein SDA1 PF05285.12 KFL62647.1 - 7.6 5.8 11.9 8.6 5.7 11.9 1.0 1 0 0 1 1 1 0 SDA1 CDC24 PF06395.11 KFL62648.1 - 7.2e-35 119.1 0.0 3.7e-34 116.8 0.0 2.1 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.20 KFL62648.1 - 1.3e-26 94.0 0.5 2.8e-26 92.9 0.5 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 KFL62648.1 - 2.8e-25 89.0 0.0 5.8e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Trns_repr_metal PF02583.17 KFL62648.1 - 0.039 14.3 0.0 13 6.3 0.0 2.6 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor PB1 PF00564.24 KFL62649.1 - 2.9e-08 33.5 0.0 4.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 PB1 domain Sod_Fe_C PF02777.18 KFL62650.1 - 1.6e-36 124.5 0.1 2.9e-36 123.7 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFL62650.1 - 1.7e-17 63.6 3.8 3e-17 62.9 3.8 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AAA PF00004.29 KFL62652.1 - 2.2e-42 144.6 0.0 4.5e-42 143.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 KFL62652.1 - 3e-28 99.0 0.0 5.9e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 KFL62652.1 - 9.1e-10 38.2 0.0 1.8e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFL62652.1 - 1.9e-05 24.7 0.0 4.8e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFL62652.1 - 2.2e-05 24.9 1.2 0.00037 20.9 0.8 2.8 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KFL62652.1 - 5.7e-05 22.5 0.0 9.5e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KFL62652.1 - 7e-05 23.1 0.2 0.0093 16.2 0.2 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFL62652.1 - 0.00045 20.0 0.0 0.0014 18.4 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFL62652.1 - 0.0015 18.7 0.0 0.0035 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFL62652.1 - 0.0048 17.1 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFL62652.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 KFL62652.1 - 0.0096 15.5 1.7 0.48 10.0 0.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KFL62652.1 - 0.015 15.8 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFL62652.1 - 0.017 14.5 0.3 0.033 13.6 0.3 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KFL62652.1 - 0.02 14.1 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase PF06745.13 KFL62652.1 - 0.028 13.8 0.1 1.2 8.5 0.0 2.6 3 0 0 3 3 3 0 KaiC NACHT PF05729.12 KFL62652.1 - 0.046 13.6 0.4 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 KFL62652.1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFL62652.1 - 0.071 13.1 0.0 0.28 11.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 KFL62652.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KFL62652.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFL62652.1 - 0.18 11.1 1.2 0.51 9.6 0.5 1.9 1 1 1 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KFL62652.1 - 0.19 11.2 0.1 0.53 9.8 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KFL62653.1 - 2.2e-42 144.6 0.0 4.4e-42 143.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 KFL62653.1 - 3e-28 98.9 0.0 5.8e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 KFL62653.1 - 9e-10 38.2 0.0 1.8e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFL62653.1 - 1.9e-05 24.7 0.0 4.8e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFL62653.1 - 2e-05 25.0 1.2 0.00036 21.0 0.8 2.8 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KFL62653.1 - 5.6e-05 22.5 0.0 9.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KFL62653.1 - 6.9e-05 23.1 0.2 0.0092 16.3 0.2 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFL62653.1 - 0.00047 19.9 0.0 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFL62653.1 - 0.0015 18.7 0.0 0.0035 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFL62653.1 - 0.0048 17.1 0.0 0.013 15.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFL62653.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 KFL62653.1 - 0.0095 15.5 1.7 0.48 10.0 0.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KFL62653.1 - 0.015 15.8 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFL62653.1 - 0.017 14.5 0.3 0.032 13.6 0.3 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KFL62653.1 - 0.019 14.1 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase PF06745.13 KFL62653.1 - 0.027 13.8 0.1 1.1 8.5 0.0 2.6 3 0 0 3 3 3 0 KaiC NACHT PF05729.12 KFL62653.1 - 0.046 13.6 0.4 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 KFL62653.1 - 0.05 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFL62653.1 - 0.076 13.1 0.0 0.28 11.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 KFL62653.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KFL62653.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFL62653.1 - 0.17 11.1 1.2 0.5 9.6 0.5 1.9 1 1 1 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KFL62653.1 - 0.19 11.3 0.1 0.53 9.8 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KFL62653.1 - 0.22 10.9 0.6 0.53 9.7 0.3 1.7 2 0 0 2 2 2 0 PhoH-like protein VPS13_C PF16909.5 KFL62654.1 - 5e-75 251.2 3.7 3e-71 238.9 0.3 2.4 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 KFL62654.1 - 0.00066 20.0 0.0 0.0036 17.6 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Transket_pyr PF02779.24 KFL62655.1 - 1.6e-66 223.4 0.0 2.8e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KFL62655.1 - 1.6e-56 190.2 0.0 2.7e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KFL62655.1 - 3e-56 190.6 0.0 4.6e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 KFL62655.1 - 3.1e-20 71.5 0.6 3.1e-20 71.5 0.6 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Transket_pyr PF02779.24 KFL62656.1 - 1.6e-66 223.4 0.0 2.8e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KFL62656.1 - 1.6e-56 190.2 0.0 2.7e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KFL62656.1 - 3e-56 190.6 0.0 4.6e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 KFL62656.1 - 3.1e-20 71.5 0.6 3.1e-20 71.5 0.6 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Transket_pyr PF02779.24 KFL62657.1 - 1.6e-66 223.4 0.0 2.8e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KFL62657.1 - 1.6e-56 190.2 0.0 2.7e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KFL62657.1 - 3e-56 190.6 0.0 4.6e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 KFL62657.1 - 3.1e-20 71.5 0.6 3.1e-20 71.5 0.6 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Transket_pyr PF02779.24 KFL62658.1 - 1.4e-66 223.6 0.0 2.4e-66 222.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KFL62658.1 - 1.4e-56 190.4 0.0 2.4e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KFL62658.1 - 2.7e-56 190.7 0.0 3.9e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 KFL62658.1 - 3.2e-11 42.6 0.4 3.2e-11 42.6 0.4 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Transket_pyr PF02779.24 KFL62659.1 - 9.4e-61 204.6 0.0 1.7e-60 203.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KFL62659.1 - 2.1e-56 191.1 0.0 3.3e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 KFL62659.1 - 2.5e-20 71.8 0.6 2.5e-20 71.8 0.6 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus E1_dh PF00676.20 KFL62660.1 - 1.5e-56 191.6 0.0 2.3e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 KFL62660.1 - 2.1e-20 72.0 0.6 2.1e-20 72.0 0.6 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Transket_pyr PF02779.24 KFL62660.1 - 1.4e-14 54.2 0.0 2.6e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KFL62661.1 - 1.5e-56 191.6 0.0 2.3e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 KFL62661.1 - 2.1e-20 72.0 0.6 2.1e-20 72.0 0.6 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Transket_pyr PF02779.24 KFL62661.1 - 1.4e-14 54.2 0.0 2.6e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Pkinase PF00069.25 KFL62662.1 - 2.2e-53 181.3 0.3 4.3e-52 177.1 0.3 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62662.1 - 7.3e-25 87.7 0.4 2.7e-19 69.5 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KFL62662.1 - 3.6e-06 26.2 0.1 5.2e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFL62662.1 - 0.00017 21.6 0.2 0.031 14.2 0.2 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFL62662.1 - 0.00055 19.3 0.2 0.0015 17.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFL62662.1 - 0.0013 18.2 0.0 0.003 16.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFL62662.1 - 0.014 15.1 0.2 2.3 7.8 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NFACT-C PF11923.8 KFL62662.1 - 0.022 14.7 0.4 0.047 13.6 0.4 1.5 1 0 0 1 1 1 0 NFACT protein C-terminal domain Pkinase_fungal PF17667.1 KFL62662.1 - 0.032 13.0 0.0 0.059 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KFL62662.1 - 0.039 13.0 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PepX_N PF09168.10 KFL62662.1 - 0.046 14.2 0.6 0.1 13.0 0.6 1.5 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Pox_ser-thr_kin PF05445.11 KFL62662.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KFL62662.1 - 0.3 10.7 2.2 0.68 9.5 0.0 2.1 2 0 0 2 2 2 0 RIO1 family adh_short PF00106.25 KFL62663.1 - 2.6e-10 40.1 0.0 2.9e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFL62663.1 - 0.00018 21.2 0.0 0.00021 20.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KFL62663.1 - 0.00019 21.4 0.0 0.00019 21.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KFL62663.1 - 0.0046 16.9 0.0 0.0049 16.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFL62663.1 - 0.013 15.0 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFL62663.1 - 0.03 13.4 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Peptidase_C14 PF00656.22 KFL62664.1 - 5.2e-62 210.0 0.0 6.9e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 KFL62665.1 - 1.9e-47 162.3 0.0 2.7e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 KFL62666.1 - 5.1e-43 147.8 0.0 6.5e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Vps26 PF03643.15 KFL62667.1 - 3.4e-101 337.8 0.2 4.1e-101 337.6 0.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Vps26 PF03643.15 KFL62668.1 - 1.2e-108 362.3 0.1 1.5e-108 362.0 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KFL62668.1 - 0.00041 20.4 0.3 1.3 9.0 0.0 2.8 2 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain IL17R_D_N PF16742.5 KFL62668.1 - 0.17 12.0 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Vps26 PF03643.15 KFL62669.1 - 2.5e-104 348.2 0.2 3e-104 347.9 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KFL62669.1 - 0.0004 20.5 0.3 1.3 9.0 0.0 2.8 2 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain IL17R_D_N PF16742.5 KFL62669.1 - 0.16 12.0 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D DUF2985 PF11204.8 KFL62670.1 - 2e-21 75.9 3.2 4.4e-21 74.8 3.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) LTXXQ PF07813.12 KFL62670.1 - 0.0019 18.9 0.3 0.0019 18.9 0.3 2.4 2 0 0 2 2 2 1 LTXXQ motif family protein NARP1 PF12569.8 KFL62670.1 - 0.43 9.4 7.0 0.83 8.5 7.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.10 KFL62670.1 - 9.3 6.3 9.1 6.4 6.8 6.1 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Cyclin_N PF00134.23 KFL62671.1 - 4.6e-46 155.7 0.1 5.6e-45 152.2 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFL62671.1 - 1.2e-18 67.4 0.1 2.5e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF2868 PF11067.8 KFL62671.1 - 1.9 7.9 7.8 0.14 11.6 2.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2868) Cyclin_N PF00134.23 KFL62672.1 - 6e-47 158.5 0.1 5.5e-45 152.2 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFL62672.1 - 2.7e-31 108.1 0.0 5.3e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF2868 PF11067.8 KFL62672.1 - 1.7 8.0 7.6 0.12 11.8 2.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2868) HLH PF00010.26 KFL62673.1 - 1.5e-11 44.1 0.0 6.3e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cpn60_TCP1 PF00118.24 KFL62680.1 - 4.6e-140 467.5 5.7 5.2e-140 467.3 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 KFL62680.1 - 0.027 14.9 0.1 11 6.6 0.0 2.7 2 0 0 2 2 2 0 Replication factor C C-terminal domain Cpn60_TCP1 PF00118.24 KFL62681.1 - 4.2e-112 375.3 2.3 4.7e-112 375.1 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 KFL62682.1 - 4.2e-112 375.3 2.3 4.7e-112 375.1 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_C14 PF00656.22 KFL62683.1 - 2.5e-60 204.5 0.0 3.4e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Ribosomal_S26e PF01283.19 KFL62684.1 - 2e-43 147.2 5.0 2.3e-43 147.0 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KFL62684.1 - 0.0046 16.9 0.1 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 Zinc binding domain DUF4668 PF15701.5 KFL62684.1 - 0.18 11.6 2.8 0.23 11.3 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) PP2C PF00481.21 KFL62686.1 - 2.9e-42 145.1 0.0 4.7e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFL62686.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Baseplate_J PF04865.14 KFL62686.1 - 0.021 14.0 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Baseplate J-like protein SpoIIE PF07228.12 KFL62686.1 - 0.18 11.7 0.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) PPDFL PF15060.6 KFL62686.1 - 1 9.9 6.1 11 6.6 0.0 2.9 2 1 0 2 2 2 0 Differentiation and proliferation regulator ALG11_N PF15924.5 KFL62687.1 - 2.8e-55 187.6 0.0 3.9e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KFL62687.1 - 1.2e-19 70.4 0.0 3e-19 69.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFL62687.1 - 4.8e-08 33.5 0.0 4.5e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFL62687.1 - 0.033 14.2 0.1 0.061 13.3 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 AAA_5 PF07728.14 KFL62687.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) WD40 PF00400.32 KFL62688.1 - 1e-05 26.2 8.7 0.17 12.8 0.8 4.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL62688.1 - 0.0017 18.6 0.8 3.9 7.8 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFL62688.1 - 0.01 15.7 0.2 1 9.2 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KFL62689.1 - 1e-05 26.2 8.7 0.17 12.8 0.8 4.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL62689.1 - 0.0017 18.6 0.8 3.9 7.8 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFL62689.1 - 0.01 15.7 0.2 1 9.2 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Histidinol_dh PF00815.20 KFL62690.1 - 1.3e-160 534.9 5.5 1.9e-160 534.4 5.5 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KFL62690.1 - 6.5e-24 83.6 0.1 1.4e-23 82.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KFL62690.1 - 2.7e-14 53.4 0.6 1.3e-13 51.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 KFL62690.1 - 0.76 10.0 3.4 0.33 11.1 0.3 2.0 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Herpes_UL56 PF04534.12 KFL62692.1 - 0.8 9.2 6.7 1 8.8 6.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein AAA_lid_3 PF17862.1 KFL62693.1 - 0.22 11.4 0.5 0.35 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA+ lid domain DUF2968 PF11180.8 KFL62695.1 - 0.00037 20.2 9.4 0.00037 20.2 9.4 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF2968) Spectrin PF00435.21 KFL62695.1 - 0.011 16.2 9.2 0.011 16.2 9.2 3.6 3 1 0 3 3 3 0 Spectrin repeat DUF4363 PF14276.6 KFL62695.1 - 0.021 14.9 4.6 0.021 14.9 4.6 4.2 3 1 0 4 4 4 0 Domain of unknown function (DUF4363) Helicase_IV_N PF12462.8 KFL62695.1 - 0.031 14.2 0.2 0.031 14.2 0.2 3.2 3 1 0 3 3 3 0 DNA helicase IV / RNA helicase N terminal APG6_N PF17675.1 KFL62695.1 - 0.12 12.9 52.3 0.025 15.1 18.0 4.5 2 1 1 4 4 4 0 Apg6 coiled-coil region Fib_alpha PF08702.10 KFL62695.1 - 1.4 9.1 35.4 0.036 14.3 4.9 4.6 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFL62695.1 - 2.1 8.4 21.0 1.6 8.8 4.3 4.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KFL62695.1 - 3.2 7.8 40.0 0.75 9.8 17.3 4.1 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 KFL62695.1 - 5.1 7.1 16.5 1.7 8.7 3.4 3.4 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.21 KFL62696.1 - 0.0049 17.3 18.2 0.0065 16.9 9.2 2.4 2 0 0 2 2 2 1 Spectrin repeat ABC_tran_CTD PF16326.5 KFL62696.1 - 0.012 15.8 2.1 0.012 15.8 2.1 3.7 3 0 0 3 3 3 0 ABC transporter C-terminal domain Helicase_IV_N PF12462.8 KFL62696.1 - 0.02 14.9 0.2 0.02 14.9 0.2 2.5 2 1 1 3 3 3 0 DNA helicase IV / RNA helicase N terminal APG6_N PF17675.1 KFL62696.1 - 0.021 15.3 18.7 0.021 15.3 18.7 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF4363 PF14276.6 KFL62696.1 - 0.025 14.7 2.1 0.025 14.7 2.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) ERM PF00769.19 KFL62696.1 - 0.043 13.6 30.1 0.093 12.5 13.9 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 KFL62696.1 - 0.3 11.1 9.9 0.66 10.0 3.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KFL62696.1 - 0.44 9.9 21.5 2.2 7.5 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Sec34 PF04136.15 KFL62696.1 - 3.7 7.4 13.4 0.1 12.4 2.2 2.9 2 1 1 3 3 3 0 Sec34-like family Vps5 PF09325.10 KFL62696.1 - 4 6.9 24.8 0.47 10.0 14.5 2.3 2 0 0 2 2 2 0 Vps5 C terminal like FUSC PF04632.12 KFL62696.1 - 4.7 5.6 5.8 9.5 4.6 0.2 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family NPV_P10 PF05531.12 KFL62696.1 - 4.7 7.7 10.3 4.5 7.8 1.0 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.12 KFL62696.1 - 6.5 6.8 34.1 0.11 12.5 2.6 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein YscO PF07321.12 KFL62696.1 - 7.6 6.5 27.0 1.9 8.4 15.1 3.5 2 1 1 3 3 3 0 Type III secretion protein YscO RNA_pol_Rpb5_C PF01191.19 KFL62697.1 - 6e-34 115.7 0.1 8.4e-34 115.3 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Mrr_cat PF04471.12 KFL62697.1 - 0.00027 20.9 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease RNA_pol_Rpb5_N PF03871.14 KFL62697.1 - 0.0065 17.0 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain BIR PF00653.21 KFL62698.1 - 8.5e-17 61.6 1.0 1.7e-16 60.6 1.0 1.6 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain BIR PF00653.21 KFL62699.1 - 1.8e-23 83.0 2.4 1.8e-22 79.7 0.2 2.1 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain MPDZ_u10 PF16667.5 KFL62699.1 - 0.043 14.7 0.5 0.086 13.8 0.1 1.6 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein Aminotran_1_2 PF00155.21 KFL62700.1 - 1.2e-45 156.2 0.0 1.4e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFL62700.1 - 0.022 13.3 0.2 0.051 12.1 0.1 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KFL62700.1 - 0.058 12.3 0.1 0.1 11.5 0.1 1.3 1 0 0 1 1 1 0 Aminotransferase class-V DUF4911 PF16256.5 KFL62700.1 - 0.15 12.1 0.1 8.9 6.4 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4911) zf-CCCH PF00642.24 KFL62703.1 - 0.00076 19.3 1.2 0.0016 18.3 1.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KFL62703.1 - 0.0076 16.5 0.2 0.016 15.4 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger containing family Torus PF16131.5 KFL62703.1 - 0.047 14.4 1.6 0.061 14.0 1.4 1.6 1 1 0 1 1 1 0 Torus domain zf_CCCH_4 PF18345.1 KFL62703.1 - 0.39 10.9 8.5 1.2 9.3 8.5 1.9 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 KFL62703.1 - 2.4 8.7 8.5 0.19 12.3 2.6 2.2 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger BRF1 PF07741.13 KFL62705.1 - 4.7e-25 87.9 3.5 6.8e-25 87.4 0.0 3.1 4 0 0 4 4 4 1 Brf1-like TBP-binding domain TFIIB PF00382.19 KFL62705.1 - 1.5e-17 63.4 0.1 2.8e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat TPT PF03151.16 KFL62706.1 - 3.4e-23 82.4 24.5 4.8e-23 81.9 24.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KFL62706.1 - 0.00032 20.0 23.0 0.00049 19.4 23.0 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFL62706.1 - 2 8.6 34.9 1.3 9.2 12.8 2.7 3 0 0 3 3 3 0 EamA-like transporter family Amino_oxidase PF01593.24 KFL62707.1 - 3.3e-05 23.4 0.0 6.4e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Amino_oxidase PF01593.24 KFL62708.1 - 0.08 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pkinase PF00069.25 KFL62709.1 - 2.3e-38 132.1 0.0 3.1e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62709.1 - 2.3e-19 69.7 0.0 3.1e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFL62709.1 - 0.00021 20.7 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFL62709.1 - 0.0024 17.8 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFL62709.1 - 0.014 15.0 0.1 1.8 8.1 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 AstB PF04996.12 KFL62709.1 - 0.17 10.5 0.1 0.25 10.0 0.1 1.2 1 0 0 1 1 1 0 Succinylarginine dihydrolase DUF846 PF05832.12 KFL62713.1 - 1.2e-37 129.0 13.4 9.9e-37 126.1 7.0 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF846) DUF846 PF05832.12 KFL62714.1 - 2.3e-42 144.4 8.9 2.6e-42 144.1 8.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) SNARE_assoc PF09335.11 KFL62715.1 - 7.4e-12 45.8 5.0 7.4e-12 45.8 5.0 2.9 2 1 1 3 3 3 1 SNARE associated Golgi protein Vma12 PF11712.8 KFL62715.1 - 0.25 11.4 0.7 0.55 10.3 0.7 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pyr_redox_2 PF07992.14 KFL62716.1 - 2.3e-48 164.9 1.0 2.8e-48 164.6 1.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFL62716.1 - 1.8e-16 60.4 0.5 8.3e-14 51.9 0.2 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFL62716.1 - 6.6e-16 58.4 0.2 3.5e-14 52.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFL62716.1 - 2.3e-05 23.8 0.7 5.8e-05 22.4 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 KFL62716.1 - 4e-05 24.0 0.0 0.011 16.1 0.0 2.6 1 1 1 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KFL62716.1 - 0.00015 21.9 0.1 0.14 12.4 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFL62716.1 - 0.004 16.4 0.1 0.56 9.3 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KFL62716.1 - 0.0093 15.2 0.2 2 7.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFL62716.1 - 0.022 14.4 4.6 8.6 5.8 0.1 3.5 2 2 2 4 4 4 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFL62716.1 - 0.027 13.8 0.3 0.097 12.0 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KFL62716.1 - 0.047 12.8 1.7 1.8 7.6 0.1 2.9 3 1 0 3 3 3 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 KFL62716.1 - 0.064 13.3 0.2 7.7 6.6 0.0 2.9 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KFL62716.1 - 0.28 10.2 4.9 0.34 9.9 0.3 2.6 2 2 0 2 2 2 0 FAD binding domain Tweety PF04906.13 KFL62718.1 - 3.2 6.3 6.2 2.9 6.4 4.8 1.5 1 1 0 1 1 1 0 Tweety Exo_endo_phos PF03372.23 KFL62719.1 - 6.6e-23 81.4 0.0 3.7e-22 79.0 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Metallophos PF00149.28 KFL62722.1 - 3.5e-19 70.1 1.2 3.8e-19 70.0 0.3 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFL62722.1 - 6.3e-07 29.7 0.0 0.0012 19.1 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain TMEM156 PF15106.6 KFL62723.1 - 0.017 14.5 0.5 0.033 13.6 0.5 1.4 1 0 0 1 1 1 0 TMEM156 protein family MARVEL PF01284.23 KFL62723.1 - 0.021 14.9 3.7 0.032 14.3 3.7 1.2 1 0 0 1 1 1 0 Membrane-associating domain SHR3_chaperone PF08229.11 KFL62723.1 - 0.038 13.0 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 EF-1_beta_acid PF10587.9 KFL62723.1 - 0.39 11.2 4.7 0.68 10.4 4.7 1.3 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Orf78 PF06024.12 KFL62723.1 - 2.4 8.5 4.4 0.69 10.2 0.1 2.2 2 1 1 3 3 3 0 Orf78 (ac78) Ost5 PF05251.12 KFL62725.1 - 2.8e-19 69.1 9.6 3.2e-19 69.0 9.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Rad1 PF02144.16 KFL62726.1 - 1.9e-87 292.8 0.1 2.2e-87 292.6 0.1 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 BPL_LplA_LipB PF03099.19 KFL62728.1 - 4.7e-05 23.3 0.0 8.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_LplA_LipB PF03099.19 KFL62729.1 - 3.4e-05 23.8 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.21 KFL62730.1 - 7.3e-125 416.0 0.0 8.3e-125 415.8 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Herpes_glycop_D PF01537.17 KFL62733.1 - 0.049 13.8 0.5 0.072 13.3 0.5 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain Pkinase PF00069.25 KFL62734.1 - 1.3e-27 96.9 0.0 1.6e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62734.1 - 2.1e-14 53.4 0.0 3.1e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFL62734.1 - 1.8e-07 30.3 0.1 2.6e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KFL62735.1 - 9.6e-16 57.9 0.0 1.2e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFL62735.1 - 1.9e-07 30.2 0.0 2.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KFL62735.1 - 2.7e-05 23.6 0.0 4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFL62736.1 - 9.6e-16 57.9 0.0 1.2e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFL62736.1 - 1.9e-07 30.2 0.0 2.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KFL62736.1 - 2.7e-05 23.6 0.0 4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFL62737.1 - 9.6e-16 57.9 0.0 1.2e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFL62737.1 - 1.9e-07 30.2 0.0 2.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KFL62737.1 - 2.7e-05 23.6 0.0 4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EMP24_GP25L PF01105.24 KFL62739.1 - 3.1e-30 105.5 0.1 4.6e-30 104.9 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TMEMspv1-c74-12 PF11044.8 KFL62739.1 - 0.16 12.0 0.1 0.16 12.0 0.1 1.7 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein HXXSHH PF07586.11 KFL62739.1 - 0.18 11.3 1.7 0.24 10.9 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1552) Meth_synt_2 PF01717.18 KFL62740.1 - 4.6e-151 502.6 0.0 1.3e-147 491.3 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KFL62740.1 - 1.4e-112 376.3 0.0 1e-106 357.0 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KFL62740.1 - 2.4e-05 23.6 0.0 0.024 13.8 0.0 2.6 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) VbhA PF18495.1 KFL62740.1 - 0.063 13.2 0.1 16 5.5 0.0 2.8 2 0 0 2 2 2 0 Antitoxin VbhA SHOCT PF09851.9 KFL62740.1 - 0.84 9.5 5.7 0.48 10.2 0.2 3.0 3 0 0 3 3 3 0 Short C-terminal domain DUF5302 PF17227.2 KFL62740.1 - 1.2 10.2 3.4 3.2 8.8 3.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5302) Meth_synt_2 PF01717.18 KFL62741.1 - 2.9e-151 503.3 0.0 9.9e-148 491.7 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KFL62741.1 - 3.3e-74 250.2 0.0 3.1e-68 230.6 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KFL62741.1 - 1.6e-05 24.2 0.0 0.02 14.1 0.0 2.6 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.9 KFL62741.1 - 0.83 9.5 5.7 0.42 10.4 0.2 2.8 3 0 0 3 3 3 0 Short C-terminal domain DUF5302 PF17227.2 KFL62741.1 - 1 10.4 3.4 2.8 9.0 3.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5302) Meth_synt_2 PF01717.18 KFL62742.1 - 2.7e-151 503.4 0.0 9.7e-148 491.7 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KFL62742.1 - 5.4e-73 246.2 0.1 5.6e-67 226.5 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KFL62742.1 - 1.5e-05 24.3 0.0 0.019 14.1 0.0 2.6 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.9 KFL62742.1 - 0.8 9.5 5.7 0.41 10.4 0.2 2.8 3 0 0 3 3 3 0 Short C-terminal domain DUF5302 PF17227.2 KFL62742.1 - 1 10.4 3.4 2.7 9.0 3.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5302) DUF3712 PF12505.8 KFL62747.1 - 0.00044 20.5 0.2 0.0048 17.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Ndc1_Nup PF09531.10 KFL62749.1 - 2.1e-196 654.3 3.3 2.4e-196 654.1 3.3 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Ndc1_Nup PF09531.10 KFL62750.1 - 1.4e-134 450.1 0.1 1.5e-134 450.0 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DEAD PF00270.29 KFL62751.1 - 2.2e-10 40.6 0.1 3.1e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFL62751.1 - 0.0024 17.9 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KFL62751.1 - 0.0089 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase_2 PF01637.18 KFL62751.1 - 0.045 13.6 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea rRNA_proc-arch PF13234.6 KFL62752.1 - 7.7e-93 311.3 1.0 1.5e-92 310.3 1.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KFL62752.1 - 6.5e-55 185.3 1.2 6.5e-55 185.3 1.2 2.2 3 0 0 3 3 3 1 DSHCT (NUC185) domain Helicase_C PF00271.31 KFL62752.1 - 1.6e-06 28.4 0.1 1.4e-05 25.4 0.1 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF5388 PF17363.2 KFL62752.1 - 0.047 13.9 0.6 0.83 9.9 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5388) rRNA_proc-arch PF13234.6 KFL62753.1 - 3.1e-75 253.6 1.0 3.1e-75 253.6 1.0 1.6 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KFL62753.1 - 2.5e-55 186.6 1.2 2.5e-55 186.6 1.2 1.9 2 1 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 KFL62754.1 - 1.3e-75 254.9 1.0 2.1e-75 254.1 1.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KFL62754.1 - 6.7e-29 100.7 2.4 7.2e-29 100.6 0.3 2.0 2 1 0 2 2 2 1 DSHCT (NUC185) domain Trypan_PARP PF05887.11 KFL62755.1 - 0.0029 17.6 2.0 0.0048 16.9 2.0 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Motile_Sperm PF00635.26 KFL62755.1 - 0.026 14.4 0.1 0.058 13.2 0.1 1.6 1 1 0 1 1 1 0 MSP (Major sperm protein) domain Trypan_PARP PF05887.11 KFL62756.1 - 0.0017 18.3 2.0 0.0028 17.6 2.0 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DotU PF09850.9 KFL62756.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Type VI secretion system protein DotU FMN_dh PF01070.18 KFL62757.1 - 2e-103 346.1 0.0 2.5e-103 345.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KFL62757.1 - 3.8e-18 65.4 0.0 7.2e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KFL62757.1 - 0.00034 19.9 0.0 0.00053 19.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KFL62757.1 - 0.001 18.4 0.0 0.075 12.3 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 KFL62757.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFL62757.1 - 0.006 15.6 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Vfa1 PF08432.10 KFL62758.1 - 8.3e-43 146.8 14.9 8.3e-43 146.8 14.9 1.6 2 0 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 KFL62758.1 - 0.0055 16.6 5.9 0.0055 16.6 5.9 1.5 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 SAGA-Tad1 PF12767.7 KFL62758.1 - 0.026 14.3 3.0 0.05 13.3 3.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CarboxypepD_reg PF13620.6 KFL62758.1 - 0.03 14.6 1.4 0.34 11.2 0.2 2.3 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain DUF4407 PF14362.6 KFL62758.1 - 0.51 9.6 5.1 0.82 9.0 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.14 KFL62758.1 - 1.1 7.4 11.3 1.6 6.9 11.3 1.2 1 0 0 1 1 1 0 CDC45-like protein MAP17 PF15807.5 KFL62758.1 - 3.5 7.9 8.7 9.3 6.5 8.7 1.7 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF724 PF05266.14 KFL62758.1 - 4 7.2 12.6 9.9 5.9 10.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PIEZO PF15917.5 KFL62758.1 - 4.8 6.6 11.7 10 5.5 11.7 1.5 1 0 0 1 1 1 0 Piezo RRN3 PF05327.11 KFL62758.1 - 6.8 5.1 14.7 9.5 4.6 14.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 V_ATPase_I PF01496.19 KFL62758.1 - 9.5 4.0 7.8 13 3.5 7.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FA_desaturase PF00487.24 KFL62759.1 - 5.8e-26 91.9 10.2 8.1e-26 91.4 10.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase ABC1 PF03109.16 KFL62760.1 - 4.2e-33 114.0 0.0 7.6e-33 113.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KFL62760.1 - 0.048 13.3 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 RIO1 family ABC1 PF03109.16 KFL62761.1 - 3.5e-33 114.3 0.0 6.4e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KFL62761.1 - 0.04 13.5 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Anp1 PF03452.14 KFL62762.1 - 1.4e-100 336.1 0.1 1.8e-100 335.7 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glyco_transf_7N PF13733.6 KFL62762.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Anp1 PF03452.14 KFL62763.1 - 1.9e-104 348.8 0.1 2.3e-104 348.5 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glyco_transf_7N PF13733.6 KFL62763.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Anp1 PF03452.14 KFL62764.1 - 5.9e-66 222.6 0.1 7.7e-66 222.2 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glyco_transf_7N PF13733.6 KFL62764.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Anp1 PF03452.14 KFL62765.1 - 5.9e-66 222.6 0.1 7.7e-66 222.2 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glyco_transf_7N PF13733.6 KFL62765.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Anp1 PF03452.14 KFL62766.1 - 7e-101 337.1 0.1 8.8e-101 336.7 0.1 1.0 1 0 0 1 1 1 1 Anp1 Glyco_transf_7N PF13733.6 KFL62766.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Anp1 PF03452.14 KFL62767.1 - 1.6e-62 211.3 0.1 2e-62 211.0 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KFL62767.1 - 0.036 13.9 0.0 0.64 9.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_7N PF13733.6 KFL62767.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Anp1 PF03452.14 KFL62768.1 - 1.6e-62 211.3 0.1 2e-62 211.0 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KFL62768.1 - 0.036 13.9 0.0 0.64 9.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_7N PF13733.6 KFL62768.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Mito_carr PF00153.27 KFL62769.1 - 1.9e-29 101.4 0.5 3.1e-17 62.3 0.1 2.7 2 1 0 2 2 2 2 Mitochondrial carrier protein Foie-gras_1 PF11817.8 KFL62771.1 - 0.1 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Foie gras liver health family 1 Sigma70_ner PF04546.13 KFL62771.1 - 8.9 6.1 7.6 4.3 7.2 5.1 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region HSP70 PF00012.20 KFL62773.1 - 3.7e-163 543.9 1.4 2.7e-162 541.1 1.4 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62773.1 - 3.5e-11 42.5 0.4 6.9e-11 41.5 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFL62773.1 - 0.0035 17.7 0.1 0.5 10.8 0.0 3.2 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 KFL62773.1 - 0.084 12.9 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62774.1 - 1.1e-163 545.7 0.1 1.9e-163 544.9 0.1 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62774.1 - 3.3e-11 42.6 0.4 6.7e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFL62774.1 - 0.0041 17.5 0.1 0.49 10.9 0.0 3.1 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 KFL62774.1 - 0.081 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62775.1 - 1.1e-163 545.7 0.1 1.9e-163 544.9 0.1 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62775.1 - 3.3e-11 42.6 0.4 6.7e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFL62775.1 - 0.0041 17.5 0.1 0.49 10.9 0.0 3.1 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 KFL62775.1 - 0.081 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62776.1 - 3.7e-167 557.1 1.4 2.1e-166 554.6 1.4 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62776.1 - 3.2e-11 42.6 0.4 6.5e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFL62776.1 - 0.0031 17.9 0.1 0.48 10.9 0.0 3.2 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 KFL62776.1 - 0.08 13.0 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62777.1 - 3.7e-167 557.1 1.4 2.1e-166 554.6 1.4 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62777.1 - 3.2e-11 42.6 0.4 6.5e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFL62777.1 - 0.0031 17.9 0.1 0.48 10.9 0.0 3.2 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 KFL62777.1 - 0.08 13.0 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62778.1 - 1.2e-167 558.8 0.1 1.5e-167 558.4 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62778.1 - 3.1e-11 42.7 0.4 6.3e-11 41.7 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFL62778.1 - 0.0037 17.7 0.1 0.46 10.9 0.0 3.1 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 KFL62778.1 - 0.077 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62779.1 - 1.2e-167 558.8 0.1 1.5e-167 558.4 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62779.1 - 3.1e-11 42.7 0.4 6.3e-11 41.7 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFL62779.1 - 0.0037 17.7 0.1 0.46 10.9 0.0 3.1 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 KFL62779.1 - 0.077 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62780.1 - 3.9e-128 428.3 1.2 3.4e-127 425.2 1.2 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62780.1 - 3.2e-11 42.6 0.0 4.9e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 KFL62780.1 - 0.073 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62781.1 - 1.6e-128 429.6 0.1 2.9e-128 428.7 0.1 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62781.1 - 3.1e-11 42.7 0.0 4.7e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 KFL62781.1 - 0.07 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62782.1 - 1.6e-128 429.6 0.1 2.9e-128 428.7 0.1 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62782.1 - 3.1e-11 42.7 0.0 4.7e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 KFL62782.1 - 0.07 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62783.1 - 3.2e-132 441.8 0.8 2.1e-131 439.1 0.8 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62783.1 - 3e-11 42.7 0.0 4.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 KFL62783.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62784.1 - 3.2e-132 441.8 0.8 2.1e-131 439.1 0.8 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62784.1 - 3e-11 42.7 0.0 4.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 KFL62784.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62785.1 - 1.7e-132 442.7 0.1 2.3e-132 442.2 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62785.1 - 2.9e-11 42.8 0.0 4.4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 KFL62785.1 - 0.066 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62786.1 - 1.7e-132 442.7 0.1 2.3e-132 442.2 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62786.1 - 2.9e-11 42.8 0.0 4.4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 KFL62786.1 - 0.066 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62787.1 - 1.7e-132 442.7 0.1 2.3e-132 442.2 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62787.1 - 2.9e-11 42.8 0.0 4.4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 KFL62787.1 - 0.066 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62788.1 - 2.6e-155 518.0 0.0 3.2e-155 517.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62788.1 - 1.6e-11 43.6 0.4 3.5e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFL62788.1 - 0.0016 18.8 0.1 0.28 11.6 0.0 3.1 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 KFL62788.1 - 0.055 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62789.1 - 2.6e-155 518.0 0.0 3.2e-155 517.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62789.1 - 1.6e-11 43.6 0.4 3.5e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFL62789.1 - 0.0016 18.8 0.1 0.28 11.6 0.0 3.1 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 KFL62789.1 - 0.055 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62790.1 - 2.6e-155 518.0 0.0 3.2e-155 517.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62790.1 - 1.6e-11 43.6 0.4 3.5e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFL62790.1 - 0.0016 18.8 0.1 0.28 11.6 0.0 3.1 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 KFL62790.1 - 0.055 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.20 KFL62791.1 - 2.6e-155 518.0 0.0 3.2e-155 517.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFL62791.1 - 1.6e-11 43.6 0.4 3.5e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFL62791.1 - 0.0016 18.8 0.1 0.28 11.6 0.0 3.1 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 KFL62791.1 - 0.055 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KFL62792.1 - 7.4e-66 222.2 0.3 1.1e-65 221.6 0.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFL62792.1 - 2.3e-41 140.3 0.5 5e-41 139.2 0.5 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KFL62792.1 - 0.0052 16.6 0.2 2.4 8.1 0.1 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KFL62792.1 - 0.025 14.2 1.6 0.11 12.0 1.3 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain MTBP_C PF14920.6 KFL62793.1 - 0.039 13.7 3.2 0.057 13.2 3.2 1.2 1 0 0 1 1 1 0 MDM2-binding DUF4130 PF13566.6 KFL62793.1 - 0.087 12.9 0.4 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4130 CENP-H PF05837.12 KFL62796.1 - 0.027 14.9 0.3 0.027 14.9 0.3 2.6 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Fez1 PF06818.15 KFL62796.1 - 0.34 11.4 15.2 1.4 9.4 14.7 2.0 1 1 0 1 1 1 0 Fez1 JmjC PF02373.22 KFL62797.1 - 7.3e-39 132.7 1.2 1.4e-38 131.8 0.5 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 KFL62797.1 - 3.3e-14 52.5 0.3 8.7e-14 51.2 0.3 1.8 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 KFL62798.1 - 5.8e-19 68.1 2.7 9.1e-19 67.5 2.7 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFL62798.1 - 2.4e-17 63.1 1.6 3.9e-17 62.4 1.6 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain Ribonuc_L-PSP PF01042.21 KFL62802.1 - 1.2e-23 83.4 0.1 1.9e-18 66.6 0.0 2.0 1 1 1 2 2 2 2 Endoribonuclease L-PSP DUF3631 PF12307.8 KFL62802.1 - 0.18 12.0 0.0 0.21 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) bZIP_2 PF07716.15 KFL62803.1 - 4.1e-13 49.2 12.1 7.3e-13 48.4 12.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFL62803.1 - 2.1e-05 24.5 10.9 3.7e-05 23.7 10.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor TFIIA PF03153.13 KFL62803.1 - 0.0011 19.1 21.9 0.0016 18.6 21.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1387 PF07139.11 KFL62803.1 - 0.0082 15.9 11.0 0.013 15.2 11.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) TSC22 PF01166.18 KFL62803.1 - 0.098 13.0 0.5 0.39 11.1 0.5 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF966 PF06136.13 KFL62803.1 - 0.98 9.1 13.6 1.3 8.7 13.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CCDC106 PF15794.5 KFL62803.1 - 2.4 7.8 16.3 2.4 7.8 1.1 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 DUF4094 PF13334.6 KFL62803.1 - 5.4 7.5 7.4 1.2 9.6 3.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DENN PF02141.21 KFL62805.1 - 7.7e-56 189.0 0.1 1.6e-55 187.9 0.1 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFL62805.1 - 1.5e-15 57.7 0.4 7.8e-15 55.4 0.0 2.5 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 KFL62805.1 - 3.1e-14 52.7 0.7 7e-14 51.5 0.7 1.7 1 0 0 1 1 1 1 dDENN domain C1_2 PF03107.16 KFL62805.1 - 1.4e-06 28.5 4.6 3.1e-06 27.4 4.6 1.6 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 KFL62805.1 - 0.0048 16.8 5.8 0.0097 15.8 5.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KFL62805.1 - 0.14 12.3 5.9 0.3 11.2 5.9 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 KFL62805.1 - 2.4 7.8 7.6 4.5 7.0 7.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KFL62805.1 - 2.8 7.9 8.7 2.1 8.3 6.5 1.9 1 1 1 2 2 2 0 PHD-finger zf-HIT PF04438.16 KFL62805.1 - 7.9 6.4 5.5 18 5.3 5.6 1.6 1 1 0 1 1 1 0 HIT zinc finger GHMP_kinases_N PF00288.26 KFL62808.1 - 1.2e-11 44.7 0.1 2.9e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFL62808.1 - 6.5e-05 23.2 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Med5 PF08689.10 KFL62809.1 - 6.4e-84 282.6 0.0 8.8e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit Med5 Med5 PF08689.10 KFL62810.1 - 7.6e-32 110.2 0.0 8.4e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 HU-CCDC81_bac_1 PF18174.1 KFL62810.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 VIT1 PF01988.19 KFL62811.1 - 0.23 11.3 0.6 0.24 11.2 0.6 1.1 1 0 0 1 1 1 0 VIT family Glycogen_syn PF05693.13 KFL62815.1 - 1.3e-268 892.9 0.2 1.5e-268 892.6 0.2 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KFL62815.1 - 1.1e-05 25.1 0.0 0.0042 16.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFL62815.1 - 1.4e-05 25.6 0.0 0.02 15.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFL62815.1 - 0.099 12.6 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glycogen_syn PF05693.13 KFL62816.1 - 9.5e-269 893.3 0.2 1.1e-268 893.1 0.2 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KFL62816.1 - 8.6e-06 25.4 0.0 0.0037 16.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFL62816.1 - 1.1e-05 25.9 0.0 0.018 15.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFL62816.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glycogen_syn PF05693.13 KFL62817.1 - 9.3e-255 847.1 0.8 1.1e-254 846.8 0.8 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KFL62817.1 - 6.2e-06 25.9 0.0 0.0031 17.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFL62817.1 - 8e-06 26.3 0.0 0.015 15.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFL62817.1 - 0.071 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 WD40 PF00400.32 KFL62818.1 - 5.1e-16 58.8 4.5 0.002 18.9 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL62818.1 - 2.5e-12 46.9 0.1 0.0017 18.6 0.0 4.5 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFL62818.1 - 2.5e-05 23.4 0.0 0.025 13.5 0.0 3.4 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFL62818.1 - 0.00029 20.7 0.2 13 5.8 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KFL62818.1 - 0.089 12.7 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KFL62818.1 - 0.094 11.2 0.0 0.72 8.3 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40 PF00400.32 KFL62819.1 - 5.1e-16 58.8 4.5 0.002 18.9 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL62819.1 - 2.5e-12 46.9 0.1 0.0017 18.6 0.0 4.5 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFL62819.1 - 2.5e-05 23.4 0.0 0.025 13.5 0.0 3.4 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFL62819.1 - 0.00029 20.7 0.2 13 5.8 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KFL62819.1 - 0.089 12.7 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KFL62819.1 - 0.094 11.2 0.0 0.72 8.3 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain SOR_SNZ PF01680.17 KFL62822.1 - 3.5e-87 291.5 1.0 3.5e-87 291.5 1.0 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 KFL62822.1 - 9.6e-09 34.9 2.3 9.5e-08 31.6 0.1 2.6 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 KFL62822.1 - 0.0013 17.9 0.1 0.23 10.5 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KFL62822.1 - 0.0017 17.9 0.1 0.023 14.2 0.0 2.5 2 1 1 3 3 3 1 Histidine biosynthesis protein TetR_C_27 PF17935.1 KFL62822.1 - 0.0031 17.6 0.0 0.0073 16.3 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 KFL62822.1 - 0.016 14.4 0.1 0.19 10.9 0.0 2.3 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 KFL62822.1 - 0.033 13.5 0.6 0.46 9.8 0.0 2.8 3 0 0 3 3 3 0 Thiamine monophosphate synthase OMPdecase PF00215.24 KFL62822.1 - 0.038 13.6 0.1 0.3 10.6 0.0 2.1 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family IGPS PF00218.21 KFL62822.1 - 0.11 11.7 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Tubulin PF00091.25 KFL62823.1 - 4.4e-65 219.6 0.0 6.9e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFL62823.1 - 1e-39 135.6 0.1 2e-39 134.6 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFL62823.1 - 0.0019 17.9 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_C PF03953.17 KFL62824.1 - 1.4e-47 160.9 0.1 2.4e-47 160.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFL62824.1 - 2.9e-38 132.1 0.0 5.1e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFL62824.1 - 0.0016 18.2 0.0 0.0046 16.7 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Tubulin_C PF03953.17 KFL62825.1 - 1.4e-47 160.9 0.1 2.4e-47 160.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFL62825.1 - 2.9e-38 132.1 0.0 5.1e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFL62825.1 - 0.0016 18.2 0.0 0.0046 16.7 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Tubulin_C PF03953.17 KFL62826.1 - 1.4e-47 160.9 0.1 2.4e-47 160.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFL62826.1 - 2.9e-38 132.1 0.0 5.1e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFL62826.1 - 0.0016 18.2 0.0 0.0046 16.7 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain DUF2012 PF09430.10 KFL62828.1 - 7.2e-23 81.0 0.0 1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) DUF2012 PF09430.10 KFL62829.1 - 5.5e-16 58.8 0.0 7.5e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) 2-Hacid_dh_C PF02826.19 KFL62830.1 - 1.5e-45 154.7 0.1 2.4e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_S8 PF00082.22 KFL62830.1 - 6.2e-42 143.9 0.7 9.9e-42 143.2 0.7 1.3 1 0 0 1 1 1 1 Subtilase family 2-Hacid_dh PF00389.30 KFL62830.1 - 2.3e-10 40.3 0.0 5.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFL62830.1 - 1.2e-05 25.6 0.2 2.7e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFL62830.1 - 0.0013 19.3 0.1 0.0032 18.0 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KFL62830.1 - 0.34 10.8 2.6 0.85 9.5 2.6 1.6 1 0 0 1 1 1 0 Rossmann-like domain DUF1996 PF09362.10 KFL62833.1 - 8.8e-45 153.5 1.0 9.6e-45 153.4 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) AdoMet_MTase PF07757.13 KFL62833.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DUF1996 PF09362.10 KFL62834.1 - 8.8e-45 153.5 1.0 9.6e-45 153.4 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) AdoMet_MTase PF07757.13 KFL62834.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase ELO PF01151.18 KFL62836.1 - 6.9e-54 183.0 18.9 8.5e-54 182.7 18.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family CAP_C PF08603.11 KFL62841.1 - 7.8e-55 184.8 1.4 1e-54 184.4 1.4 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 KFL62841.1 - 3.3e-47 161.5 1.7 3.3e-47 161.5 1.7 1.6 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 KFL62841.1 - 0.031 14.0 3.1 0.86 9.4 2.6 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C Ribosomal_60s PF00428.19 KFL62841.1 - 0.27 11.8 4.1 0.17 12.5 1.4 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein PRIMA1 PF16101.5 KFL62841.1 - 2.3 8.2 13.2 0.62 10.1 9.1 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_C PF08603.11 KFL62842.1 - 5.3e-55 185.3 1.4 6.6e-55 185.0 1.4 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 KFL62842.1 - 5.3e-26 91.9 11.9 5.3e-26 91.9 11.9 1.6 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 KFL62842.1 - 0.016 14.9 2.8 0.64 9.8 2.6 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor C PRIMA1 PF16101.5 KFL62842.1 - 1 9.4 12.7 0.31 11.1 8.5 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Herpes_pp85 PF04637.12 KFL62843.1 - 0.15 10.4 0.4 0.22 9.9 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PSI_integrin PF17205.3 KFL62844.1 - 0.0058 16.4 0.3 0.01 15.5 0.3 1.4 1 0 0 1 1 1 1 Integrin plexin domain AMP-binding PF00501.28 KFL62846.1 - 1.8e-17 63.1 0.0 2.1e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KFL62847.1 - 2.3e-35 122.0 0.0 3e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFL62847.1 - 3e-15 57.0 0.1 7.3e-15 55.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CH PF00307.31 KFL62849.1 - 1.5e-29 102.3 0.0 7.9e-24 83.9 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFL62849.1 - 1.2e-07 31.5 0.0 3.4e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain EF-hand_6 PF13405.6 KFL62849.1 - 0.0013 18.4 0.0 0.0063 16.4 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain Spectrin PF00435.21 KFL62849.1 - 0.007 16.8 5.3 0.55 10.7 0.0 2.7 1 1 0 2 2 2 1 Spectrin repeat EF-hand_8 PF13833.6 KFL62849.1 - 0.0074 16.1 0.3 0.037 13.9 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFL62849.1 - 0.013 15.0 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 0 EF hand SKA1 PF07160.12 KFL62849.1 - 0.089 12.6 1.5 0.15 11.9 0.9 1.6 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 EF-hand_7 PF13499.6 KFL62849.1 - 0.21 12.0 2.5 0.74 10.3 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain pair Hom_end_hint PF05203.16 KFL62849.1 - 0.4 10.6 1.4 0.93 9.4 1.1 1.7 1 1 1 2 2 2 0 Hom_end-associated Hint FliG_N PF14842.6 KFL62849.1 - 0.63 10.6 2.6 2.3 8.8 0.1 2.8 3 1 1 4 4 3 0 FliG N-terminal domain Baculo_PEP_C PF04513.12 KFL62849.1 - 4.4 7.4 5.2 1.6 8.7 0.5 2.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AMP-binding PF00501.28 KFL62851.1 - 4.8e-68 229.7 0.2 5.7e-68 229.4 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFL62851.1 - 2.3e-13 50.9 0.5 6.4e-13 49.5 0.3 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFL62852.1 - 4.8e-68 229.7 0.2 5.7e-68 229.4 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFL62852.1 - 2.3e-13 50.9 0.5 6.4e-13 49.5 0.3 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFL62853.1 - 2.2e-55 188.0 0.3 2.6e-55 187.8 0.3 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KFL62854.1 - 2.2e-55 188.0 0.3 2.6e-55 187.8 0.3 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Matrilin_ccoil PF10393.9 KFL62856.1 - 0.63 9.9 2.2 1.3 8.9 2.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Mst1_SARAH PF11629.8 KFL62856.1 - 1.8 8.7 4.4 53 4.0 0.0 3.5 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 Spermine_synth PF01564.17 KFL62857.1 - 1.8e-05 24.2 0.1 3.5e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 KFL62857.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 KFL62857.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 KFL62857.1 - 0.16 12.8 0.0 0.79 10.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain RskA PF10099.9 KFL62857.1 - 0.63 10.3 5.9 1.2 9.4 5.9 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4112 PF13430.6 KFL62858.1 - 0.058 13.7 0.2 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) Septin PF00735.18 KFL62859.1 - 1.4e-100 336.2 0.5 2.1e-100 335.7 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFL62859.1 - 0.00071 19.6 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFL62859.1 - 0.029 14.4 2.4 1 9.4 0.0 3.1 2 1 1 3 3 3 0 Dynamin family GTP_EFTU PF00009.27 KFL62859.1 - 0.034 13.7 0.5 1.9 8.0 0.1 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain EB1 PF03271.17 KFL62859.1 - 0.27 11.5 4.3 3.2 8.1 1.3 2.8 2 0 0 2 2 2 0 EB1-like C-terminal motif Septin PF00735.18 KFL62860.1 - 9.5e-101 336.8 0.0 1.1e-100 336.5 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFL62860.1 - 0.00061 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFL62860.1 - 0.017 14.7 0.1 1.4 8.4 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KFL62860.1 - 0.019 15.0 0.0 0.72 9.9 0.0 2.4 1 1 1 2 2 2 0 Dynamin family CNH PF00780.22 KFL62861.1 - 3e-81 273.0 0.0 2e-80 270.4 0.0 2.0 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KFL62861.1 - 1.1e-39 135.6 0.0 2.4e-39 134.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KFL62861.1 - 8.8e-38 130.4 0.0 1.6e-37 129.5 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KFL62861.1 - 3.8e-13 49.3 0.0 8.2e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.6 KFL62862.1 - 9.3e-40 135.9 0.0 2e-39 134.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KFL62862.1 - 7.8e-38 130.5 0.0 1.4e-37 129.7 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 KFL62862.1 - 1.1e-23 84.3 0.0 8.4e-23 81.4 0.0 2.0 2 0 0 2 2 2 1 CNH domain DEP PF00610.21 KFL62862.1 - 3.3e-13 49.5 0.0 7.2e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 KFL62862.1 - 0.14 11.9 0.0 0.47 10.2 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PH_5 PF15405.6 KFL62863.1 - 7.7e-40 136.1 0.0 1.6e-39 135.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KFL62863.1 - 6.4e-38 130.8 0.0 1.1e-37 130.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KFL62863.1 - 2.7e-13 49.8 0.0 5.9e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 KFL62863.1 - 0.12 12.2 0.1 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain PH_5 PF15405.6 KFL62864.1 - 7.7e-40 136.1 0.0 1.6e-39 135.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KFL62864.1 - 6.4e-38 130.8 0.0 1.1e-37 130.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KFL62864.1 - 2.7e-13 49.8 0.0 5.9e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 KFL62864.1 - 0.12 12.2 0.1 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain ATP-synt_C PF00137.21 KFL62865.1 - 1.6e-18 66.7 27.3 1.5e-12 47.6 16.2 2.2 2 0 0 2 2 2 2 ATP synthase subunit C ATP-synt_C PF00137.21 KFL62866.1 - 6.4e-31 106.5 39.1 5.6e-18 65.0 14.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C APH PF01636.23 KFL62869.1 - 7.1e-07 29.4 0.0 7.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFL62869.1 - 6.7e-05 22.6 0.3 8.3e-05 22.3 0.3 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.11 KFL62869.1 - 0.029 14.0 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF4325 PF14213.6 KFL62869.1 - 0.033 13.9 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) Pkinase PF00069.25 KFL62869.1 - 0.057 12.8 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain PIP49_C PF12260.8 KFL62869.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 CAP PF00188.26 KFL62871.1 - 3.9e-05 24.5 0.8 5.5e-05 24.0 0.8 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CHCH PF06747.13 KFL62872.1 - 5.6e-06 26.3 15.0 0.00015 21.8 9.0 2.3 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 KFL62872.1 - 1.8e-05 24.6 10.1 0.00011 22.1 6.9 2.2 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KFL62872.1 - 0.053 13.8 9.1 0.83 10.0 1.6 3.0 2 1 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 KFL62872.1 - 0.77 10.0 11.9 3 8.1 5.4 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 KFL62872.1 - 2.3 8.3 15.0 7 6.7 1.1 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CBF PF03914.17 KFL62874.1 - 9.2e-56 188.5 1.8 1.9e-55 187.5 0.2 2.4 2 0 0 2 2 2 1 CBF/Mak21 family Adaptin_N PF01602.20 KFL62874.1 - 0.00081 18.1 0.8 0.018 13.6 0.1 2.2 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 KFL62874.1 - 0.065 13.3 0.6 0.94 9.5 0.0 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Prok-E2_C PF14459.6 KFL62874.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family C TAFH PF07531.14 KFL62874.1 - 0.074 13.2 0.5 14 5.8 0.1 2.9 2 0 0 2 2 2 0 NHR1 homology to TAF Tubulin PF00091.25 KFL62875.1 - 1e-68 231.4 0.0 2.2e-68 230.4 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFL62875.1 - 1.3e-43 148.2 0.1 2.1e-43 147.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFL62875.1 - 2.1e-05 24.8 0.0 5.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KFL62875.1 - 0.00085 18.6 0.0 0.034 13.4 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KFL62875.1 - 0.0043 16.8 0.0 0.0092 15.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KFL62876.1 - 9.7e-69 231.5 0.0 2e-68 230.5 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFL62876.1 - 1.2e-43 148.2 0.1 2e-43 147.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFL62876.1 - 2.3e-05 24.7 0.0 5.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KFL62876.1 - 0.00081 18.7 0.0 0.032 13.4 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KFL62876.1 - 0.0042 16.8 0.0 0.0088 15.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KFL62877.1 - 6.3e-69 232.1 0.0 8.6e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFL62877.1 - 7.7e-17 61.6 0.1 1.3e-16 60.9 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFL62877.1 - 1.7e-05 25.1 0.0 3.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KFL62877.1 - 0.0034 17.1 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFL62877.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Tubulin like TrmK PF04816.12 KFL62877.1 - 0.21 11.1 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Aldedh PF00171.22 KFL62878.1 - 3.4e-97 325.8 0.0 3.9e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Nup84_Nup100 PF04121.13 KFL62880.1 - 4e-174 580.6 3.0 5.2e-174 580.3 3.0 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 HBM PF16591.5 KFL62880.1 - 0.017 14.6 0.9 0.017 14.6 0.9 2.0 2 0 0 2 2 2 0 Helical bimodular sensor domain PEP-utilizers_C PF02896.18 KFL62880.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Nup84_Nup100 PF04121.13 KFL62881.1 - 6.8e-176 586.5 1.1 8.7e-176 586.2 1.1 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 HBM PF16591.5 KFL62881.1 - 0.017 14.6 0.9 0.017 14.6 0.9 1.8 2 0 0 2 2 2 0 Helical bimodular sensor domain PEP-utilizers_C PF02896.18 KFL62881.1 - 0.15 11.2 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Nup84_Nup100 PF04121.13 KFL62882.1 - 3.1e-173 577.7 1.0 4e-173 577.4 1.0 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 HBM PF16591.5 KFL62882.1 - 0.017 14.6 0.9 0.017 14.6 0.9 1.8 2 0 0 2 2 2 0 Helical bimodular sensor domain PEP-utilizers_C PF02896.18 KFL62882.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Nup84_Nup100 PF04121.13 KFL62883.1 - 9.1e-177 589.4 3.2 1.2e-176 589.0 3.2 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 HBM PF16591.5 KFL62883.1 - 0.017 14.6 0.9 0.017 14.6 0.9 2.0 2 0 0 2 2 2 0 Helical bimodular sensor domain PEP-utilizers_C PF02896.18 KFL62883.1 - 0.14 11.2 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Nup84_Nup100 PF04121.13 KFL62884.1 - 1.4e-144 483.0 3.9 2e-144 482.5 3.9 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 HBM PF16591.5 KFL62884.1 - 0.014 14.9 0.9 0.014 14.9 0.9 1.8 2 0 0 2 2 2 0 Helical bimodular sensor domain PEP-utilizers_C PF02896.18 KFL62884.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Nup84_Nup100 PF04121.13 KFL62885.1 - 3.4e-147 491.6 4.2 4.8e-147 491.1 4.2 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 HBM PF16591.5 KFL62885.1 - 0.013 14.9 0.9 0.013 14.9 0.9 1.8 2 0 0 2 2 2 0 Helical bimodular sensor domain PEP-utilizers_C PF02896.18 KFL62885.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Nup84_Nup100 PF04121.13 KFL62886.1 - 3.4e-147 491.6 4.2 4.8e-147 491.1 4.2 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 HBM PF16591.5 KFL62886.1 - 0.013 14.9 0.9 0.013 14.9 0.9 1.8 2 0 0 2 2 2 0 Helical bimodular sensor domain PEP-utilizers_C PF02896.18 KFL62886.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Cation_ATPase_C PF00689.21 KFL62887.1 - 8e-46 156.0 4.8 8e-46 156.0 4.8 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFL62887.1 - 1.9e-34 118.7 4.6 1.9e-34 118.7 4.6 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFL62887.1 - 7.9e-24 83.6 0.1 1.5e-23 82.7 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFL62887.1 - 7.2e-16 59.1 1.7 7.7e-15 55.7 1.7 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFL62887.1 - 1.4e-06 27.9 0.0 1.1e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFL62887.1 - 3.5e-05 23.7 0.6 9.2e-05 22.3 0.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RskA PF10099.9 KFL62887.1 - 0.0093 16.3 1.0 3.1 8.1 0.0 3.3 2 1 0 2 2 2 1 Anti-sigma-K factor rskA LptF_LptG PF03739.14 KFL62887.1 - 0.016 14.1 5.7 0.041 12.7 5.7 1.7 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF1774 PF08611.10 KFL62887.1 - 0.17 12.2 5.3 0.13 12.6 0.4 2.8 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) Ligase_CoA PF00549.19 KFL62888.1 - 9.5e-10 38.5 0.6 1.2e-09 38.2 0.6 1.1 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KFL62888.1 - 3.2e-07 30.2 0.1 4e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain Ligase_CoA PF00549.19 KFL62889.1 - 1.3e-20 73.7 0.3 2.1e-18 66.6 0.1 2.3 2 0 0 2 2 2 2 CoA-ligase Citrate_bind PF16114.5 KFL62889.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding 4HBT PF03061.22 KFL62890.1 - 7.6e-11 42.2 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily V-ATPase_C PF03223.15 KFL62891.1 - 4.3e-115 385.1 0.0 5.2e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.15 KFL62891.1 - 0.03 15.0 0.1 0.058 14.0 0.1 1.5 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Cep57_MT_bd PF06657.13 KFL62891.1 - 0.13 12.8 0.4 23 5.5 0.1 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Ank_2 PF12796.7 KFL62892.1 - 0.0011 19.5 0.0 0.0078 16.8 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFL62892.1 - 0.0017 18.8 0.0 0.0068 17.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Cation_ATPase_C PF00689.21 KFL62893.1 - 0.14 11.9 0.0 0.54 9.9 0.0 2.0 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus HlyD_D23 PF16576.5 KFL62896.1 - 0.02 14.1 3.3 0.035 13.3 3.3 1.4 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Methyltransf_PK PF05891.12 KFL62896.1 - 0.052 13.1 0.3 0.068 12.7 0.3 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase LPP20 PF02169.16 KFL62896.1 - 2.1 8.7 8.3 2.6 8.5 3.8 2.5 1 1 1 2 2 2 0 LPP20 lipoprotein CENP-H PF05837.12 KFL62896.1 - 6.7 7.2 10.6 2.5 8.6 5.6 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ApoLp-III PF07464.11 KFL62897.1 - 0.039 14.1 1.0 0.061 13.4 1.0 1.4 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Cauli_AT PF03233.13 KFL62897.1 - 0.11 12.4 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Aphid transmission protein LrgB PF04172.16 KFL62899.1 - 0.0085 15.6 1.5 0.0085 15.6 1.5 2.3 2 1 0 2 2 2 1 LrgB-like family DUF2569 PF10754.9 KFL62899.1 - 0.2 12.1 14.1 0.25 11.8 4.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) Pkinase PF00069.25 KFL62900.1 - 1.7e-57 194.8 0.0 2.9e-57 194.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFL62900.1 - 3.6e-33 114.9 0.0 5.3e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFL62900.1 - 2.7e-17 62.3 0.4 5.8e-17 61.2 0.4 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 KFL62900.1 - 5.7e-06 25.8 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFL62900.1 - 3.4e-05 23.3 0.0 6.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFL62900.1 - 0.00021 20.4 0.1 0.00035 19.6 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFL62900.1 - 0.0059 16.5 0.0 0.038 13.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFL62900.1 - 0.064 12.8 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KFL62900.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Nop52 PF05997.12 KFL62901.1 - 5.7e-25 88.4 0.6 1.1e-23 84.2 0.6 2.1 1 1 0 1 1 1 1 Nucleolar protein,Nop52 Ion_trans PF00520.31 KFL62902.1 - 4e-125 415.9 90.3 1.9e-39 135.3 8.9 4.6 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.32 KFL62902.1 - 0.0024 17.3 0.0 0.0075 15.7 0.0 1.9 1 0 0 1 1 1 1 EF hand GPHH PF16905.5 KFL62902.1 - 0.014 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated FUN14 PF04930.15 KFL62902.1 - 0.044 14.2 0.3 23 5.5 0.0 2.9 2 0 0 2 2 2 0 FUN14 family EF-hand_6 PF13405.6 KFL62902.1 - 0.063 13.2 0.0 0.41 10.7 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain Aft1_OSA PF11785.8 KFL62902.1 - 0.69 10.4 2.9 1.9 9.0 2.9 1.7 1 0 0 1 1 1 0 Aft1 osmotic stress response (OSM) domain Ribosomal_L6e PF01159.19 KFL62903.1 - 6.5e-15 55.6 0.1 1.2e-14 54.8 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L6e adh_short PF00106.25 KFL62904.1 - 4.9e-18 65.3 0.0 6.8e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFL62904.1 - 1e-10 41.6 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFL62904.1 - 2.8e-05 24.1 0.0 0.00024 21.1 0.0 2.0 1 1 0 1 1 1 1 KR domain RNB PF00773.19 KFL62905.1 - 3.6e-79 266.5 0.0 9.7e-79 265.0 0.0 1.8 2 0 0 2 2 2 1 RNB domain Dis3l2_C_term PF17877.1 KFL62905.1 - 2.2e-25 88.8 0.0 6.8e-25 87.2 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 KFL62905.1 - 1.4e-24 85.9 0.0 3.2e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KFL62905.1 - 0.0007 19.7 0.0 0.24 11.6 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KFL62905.1 - 0.0015 18.2 0.0 0.0046 16.7 0.0 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain TFIIA PF03153.13 KFL62905.1 - 0.0056 16.7 14.2 0.0056 16.7 14.2 3.4 2 1 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF4667 PF15700.5 KFL62905.1 - 0.0089 16.1 3.0 0.0089 16.1 3.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4667) RNB PF00773.19 KFL62906.1 - 2.2e-57 194.8 0.0 6.8e-57 193.2 0.0 1.8 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 KFL62906.1 - 9.7e-25 86.4 0.0 2.3e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KFL62906.1 - 0.00036 20.6 0.0 0.17 12.1 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KFL62906.1 - 0.0019 17.9 0.9 0.0032 17.2 0.0 1.8 2 0 0 2 2 2 1 Rrp44-like cold shock domain TFIIA PF03153.13 KFL62906.1 - 0.0037 17.3 14.3 0.0037 17.3 14.3 2.3 1 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF4667 PF15700.5 KFL62906.1 - 0.0059 16.7 3.0 0.0059 16.7 3.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) DUF836 PF05768.14 KFL62908.1 - 2.1e-13 50.5 0.0 2.4e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KFL62908.1 - 0.007 16.6 0.0 0.0098 16.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin SURF4 PF02077.15 KFL62910.1 - 2.8e-94 315.7 7.1 3.1e-94 315.5 7.1 1.0 1 0 0 1 1 1 1 SURF4 family DUF1405 PF07187.11 KFL62910.1 - 0.0096 15.9 3.0 0.0096 15.9 3.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1405) DoxX PF07681.12 KFL62910.1 - 0.03 14.9 20.1 0.11 13.2 5.1 3.1 3 2 0 3 3 3 0 DoxX UPF0139 PF03669.13 KFL62910.1 - 0.043 13.7 0.7 0.043 13.7 0.7 2.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0139) TMIE PF16038.5 KFL62910.1 - 4.5 7.2 6.7 12 5.8 0.4 2.7 2 0 0 2 2 2 0 TMIE protein SURF4 PF02077.15 KFL62911.1 - 4.7e-71 239.5 8.5 5.7e-71 239.2 8.5 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 KFL62911.1 - 0.00072 20.1 14.4 0.093 13.3 5.1 2.7 2 2 0 2 2 2 2 DoxX UPF0139 PF03669.13 KFL62911.1 - 0.22 11.4 4.2 0.051 13.4 0.9 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.15 KFL62912.1 - 4.7e-71 239.5 8.5 5.7e-71 239.2 8.5 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 KFL62912.1 - 0.00072 20.1 14.4 0.093 13.3 5.1 2.7 2 2 0 2 2 2 2 DoxX UPF0139 PF03669.13 KFL62912.1 - 0.22 11.4 4.2 0.051 13.4 0.9 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.15 KFL62913.1 - 4.7e-71 239.5 8.5 5.7e-71 239.2 8.5 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 KFL62913.1 - 0.00072 20.1 14.4 0.093 13.3 5.1 2.7 2 2 0 2 2 2 2 DoxX UPF0139 PF03669.13 KFL62913.1 - 0.22 11.4 4.2 0.051 13.4 0.9 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.15 KFL62914.1 - 1.6e-80 270.5 6.5 1.9e-80 270.3 6.5 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 KFL62914.1 - 0.00081 19.9 14.7 0.088 13.4 5.1 2.7 2 2 0 2 2 2 2 DoxX DUF1405 PF07187.11 KFL62914.1 - 0.01 15.8 2.2 0.01 15.8 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1405) UPF0139 PF03669.13 KFL62914.1 - 0.023 14.6 0.2 0.023 14.6 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.15 KFL62915.1 - 1.6e-80 270.5 6.5 1.9e-80 270.3 6.5 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 KFL62915.1 - 0.00081 19.9 14.7 0.088 13.4 5.1 2.7 2 2 0 2 2 2 2 DoxX DUF1405 PF07187.11 KFL62915.1 - 0.01 15.8 2.2 0.01 15.8 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1405) UPF0139 PF03669.13 KFL62915.1 - 0.023 14.6 0.2 0.023 14.6 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.15 KFL62916.1 - 1.9e-77 260.4 10.8 2.2e-77 260.3 10.8 1.0 1 0 0 1 1 1 1 SURF4 family DUF1405 PF07187.11 KFL62916.1 - 0.0038 17.2 2.6 0.0038 17.2 2.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1405) UPF0139 PF03669.13 KFL62916.1 - 0.024 14.5 0.8 0.024 14.5 0.8 2.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.15 KFL62917.1 - 1.9e-77 260.4 10.8 2.2e-77 260.3 10.8 1.0 1 0 0 1 1 1 1 SURF4 family DUF1405 PF07187.11 KFL62917.1 - 0.0038 17.2 2.6 0.0038 17.2 2.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1405) UPF0139 PF03669.13 KFL62917.1 - 0.024 14.5 0.8 0.024 14.5 0.8 2.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.15 KFL62918.1 - 1.9e-77 260.4 10.8 2.2e-77 260.3 10.8 1.0 1 0 0 1 1 1 1 SURF4 family DUF1405 PF07187.11 KFL62918.1 - 0.0038 17.2 2.6 0.0038 17.2 2.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1405) UPF0139 PF03669.13 KFL62918.1 - 0.024 14.5 0.8 0.024 14.5 0.8 2.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.15 KFL62919.1 - 1.3e-71 241.4 12.9 1.4e-71 241.3 12.9 1.0 1 0 0 1 1 1 1 SURF4 family DUF1405 PF07187.11 KFL62919.1 - 0.0033 17.4 2.6 0.0033 17.4 2.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1405) UPF0139 PF03669.13 KFL62919.1 - 0.022 14.6 0.8 0.022 14.6 0.8 2.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.15 KFL62920.1 - 1.3e-71 241.4 12.9 1.4e-71 241.3 12.9 1.0 1 0 0 1 1 1 1 SURF4 family DUF1405 PF07187.11 KFL62920.1 - 0.0033 17.4 2.6 0.0033 17.4 2.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1405) UPF0139 PF03669.13 KFL62920.1 - 0.022 14.6 0.8 0.022 14.6 0.8 2.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.15 KFL62921.1 - 1.3e-71 241.4 12.9 1.4e-71 241.3 12.9 1.0 1 0 0 1 1 1 1 SURF4 family DUF1405 PF07187.11 KFL62921.1 - 0.0033 17.4 2.6 0.0033 17.4 2.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1405) UPF0139 PF03669.13 KFL62921.1 - 0.022 14.6 0.8 0.022 14.6 0.8 2.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.15 KFL62922.1 - 1.3e-71 241.4 12.9 1.4e-71 241.3 12.9 1.0 1 0 0 1 1 1 1 SURF4 family DUF1405 PF07187.11 KFL62922.1 - 0.0033 17.4 2.6 0.0033 17.4 2.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1405) UPF0139 PF03669.13 KFL62922.1 - 0.022 14.6 0.8 0.022 14.6 0.8 2.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0139) Amidase PF01425.21 KFL62924.1 - 1.4e-80 271.4 0.0 1.8e-80 271.1 0.0 1.0 1 0 0 1 1 1 1 Amidase FA_hydroxylase PF04116.13 KFL62925.1 - 1.8e-06 28.4 5.3 2.2e-06 28.0 4.4 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.13 KFL62926.1 - 9.8e-06 25.9 1.5 3.5e-05 24.2 1.5 1.8 1 1 0 1 1 1 1 Fatty acid hydroxylase superfamily FA_desaturase PF00487.24 KFL62926.1 - 0.052 13.4 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase AlaDh_PNT_N PF05222.15 KFL62928.1 - 1.3e-39 135.6 0.0 1.7e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_N PF05222.15 KFL62929.1 - 1.3e-39 135.6 0.0 1.7e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB PF02233.16 KFL62930.1 - 2e-176 587.5 25.5 2e-176 587.5 25.5 1.9 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit PNTB_4TM PF12769.7 KFL62930.1 - 2.4e-30 104.8 3.0 2.4e-30 104.8 3.0 5.5 3 1 3 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch TPP_enzyme_M PF00205.22 KFL62930.1 - 0.015 15.0 0.9 0.11 12.2 0.5 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain PH_6 PF15406.6 KFL62933.1 - 2.3e-36 124.5 2.5 4.1e-36 123.7 2.5 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFL62933.1 - 5.1e-10 39.8 0.1 1.5e-09 38.3 0.1 1.7 1 1 0 1 1 1 1 PH domain PH_13 PF16652.5 KFL62933.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain STAS PF01740.21 KFL62934.1 - 3.4e-11 42.8 0.1 6.4e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 KFL62934.1 - 4.4e-07 29.0 0.8 4.4e-07 29.0 0.8 1.7 2 0 0 2 2 2 1 Sulfate permease family DUF1967 PF09269.11 KFL62934.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Sulfate_transp PF00916.20 KFL62935.1 - 4.1e-28 98.2 11.6 5.8e-28 97.7 11.6 1.1 1 0 0 1 1 1 1 Sulfate permease family Sld5 PF05916.11 KFL62936.1 - 1.8e-12 47.7 0.4 6e-12 46.0 0.3 1.9 1 1 1 2 2 2 2 GINS complex protein PAP_RNA-bind PF04926.15 KFL62942.1 - 2.7e-12 46.7 0.4 6.6e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain PAP_central PF04928.17 KFL62943.1 - 1.4e-108 361.6 0.0 1.7e-108 361.3 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KFL62943.1 - 9.4e-40 136.0 0.0 1.4e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KFL62943.1 - 2.4e-12 47.0 0.0 4.8e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KFL62943.1 - 0.11 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain FliH PF02108.16 KFL62944.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Flagellar assembly protein FliH Pyr_redox_2 PF07992.14 KFL62945.1 - 1.5e-52 178.6 0.3 2e-52 178.3 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFL62945.1 - 2.7e-14 53.5 0.1 2.7e-14 53.5 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFL62945.1 - 1.5e-10 40.8 0.8 3e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFL62945.1 - 0.0084 15.3 0.0 0.022 13.9 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 KFL62945.1 - 0.041 13.8 0.1 0.08 12.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KFL62945.1 - 0.66 9.0 2.8 0.6 9.1 0.4 2.1 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KFL62946.1 - 8.8e-42 143.3 0.1 1.4e-41 142.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFL62946.1 - 1.8e-30 105.4 0.1 4.6e-30 104.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFL62946.1 - 1.1e-14 54.7 0.1 2.6e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFL62946.1 - 1.9e-09 37.2 0.0 2.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFL62946.1 - 0.013 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 KFL62946.1 - 0.04 13.8 0.1 0.077 12.9 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 KFL62949.1 - 3.2e-09 36.1 1.2 5e-09 35.5 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFL62949.1 - 1.9e-07 31.1 15.5 1.9e-07 31.1 15.5 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT_EZ PF13513.6 KFL62951.1 - 2.3e-30 104.6 12.4 1.4e-15 57.4 0.0 10.2 7 3 4 11 11 11 5 HEAT-like repeat HEAT PF02985.22 KFL62951.1 - 4.9e-23 79.2 18.3 7.3e-05 22.7 0.0 11.8 14 0 0 14 14 13 3 HEAT repeat HEAT_2 PF13646.6 KFL62951.1 - 4.6e-18 65.4 2.8 2e-05 24.9 0.0 8.1 5 3 3 8 8 8 3 HEAT repeats Cnd1 PF12717.7 KFL62951.1 - 2e-12 47.5 0.0 0.00055 20.0 0.0 5.9 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFL62951.1 - 1e-08 35.6 0.0 0.04 14.5 0.0 5.0 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KFL62951.1 - 1.5e-08 34.2 6.1 0.4 9.7 0.2 5.4 5 1 0 5 5 5 3 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KFL62951.1 - 4.6e-08 32.9 0.6 0.0044 16.6 0.2 6.0 3 3 1 4 4 4 1 CLASP N terminal Xpo1 PF08389.12 KFL62951.1 - 2e-05 24.7 0.1 0.00047 20.2 0.0 3.4 4 1 0 4 4 2 1 Exportin 1-like protein RIX1 PF08167.12 KFL62951.1 - 4.8e-05 23.2 0.9 3 7.6 0.0 5.5 5 1 1 6 6 6 1 rRNA processing/ribosome biogenesis IBN_N PF03810.19 KFL62951.1 - 7.2e-05 22.6 0.8 0.012 15.5 0.0 4.3 3 2 1 4 4 4 1 Importin-beta N-terminal domain Sec7_N PF12783.7 KFL62951.1 - 0.00029 20.8 0.3 0.0096 15.8 0.1 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Adaptin_N PF01602.20 KFL62951.1 - 0.00052 18.7 0.4 0.16 10.5 0.0 4.1 3 2 1 4 4 4 1 Adaptin N terminal region Dopey_N PF04118.14 KFL62951.1 - 0.00057 19.1 0.1 0.053 12.6 0.0 2.7 3 0 0 3 3 3 1 Dopey, N-terminal Arm PF00514.23 KFL62951.1 - 0.00098 19.1 7.1 2 8.6 0.0 6.4 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 KFL62951.1 - 0.0012 18.7 1.5 0.16 11.9 0.0 4.6 6 0 0 6 6 5 1 Domain of unknown function (DUF3437) RTP1_C1 PF10363.9 KFL62951.1 - 0.0043 17.2 0.0 0.029 14.5 0.0 2.5 2 0 0 2 2 1 1 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 KFL62951.1 - 0.083 12.6 0.0 2.4 7.8 0.0 2.7 3 0 0 3 3 3 0 DNA alkylation repair enzyme HEAT_PBS PF03130.16 KFL62951.1 - 0.14 12.9 4.2 26 5.9 0.0 5.3 7 0 0 7 7 3 0 PBS lyase HEAT-like repeat TAFH PF07531.14 KFL62951.1 - 0.69 10.1 6.6 20 5.4 0.0 5.2 6 0 0 6 6 5 0 NHR1 homology to TAF HEAT_EZ PF13513.6 KFL62952.1 - 1.3e-29 102.2 14.9 1.4e-15 57.4 0.0 10.2 8 3 4 12 12 11 5 HEAT-like repeat HEAT PF02985.22 KFL62952.1 - 3.5e-23 79.7 17.0 7.2e-05 22.7 0.0 11.3 13 0 0 13 13 12 3 HEAT repeat HEAT_2 PF13646.6 KFL62952.1 - 5.7e-17 61.9 0.7 2e-05 24.9 0.0 7.5 5 3 3 8 8 7 3 HEAT repeats Cnd1 PF12717.7 KFL62952.1 - 3.5e-11 43.4 0.0 0.00054 20.0 0.0 5.0 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFL62952.1 - 1e-08 35.6 0.0 0.04 14.5 0.0 4.9 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KFL62952.1 - 1.2e-08 34.5 5.8 0.39 9.8 0.2 5.4 5 1 0 5 5 5 3 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KFL62952.1 - 4.7e-08 32.9 0.7 0.0043 16.6 0.2 6.0 3 3 1 4 4 4 1 CLASP N terminal Xpo1 PF08389.12 KFL62952.1 - 1.8e-05 24.8 0.1 0.00047 20.3 0.0 3.4 4 1 0 4 4 2 1 Exportin 1-like protein RIX1 PF08167.12 KFL62952.1 - 4.4e-05 23.3 0.9 3 7.6 0.0 5.5 5 1 1 6 6 6 1 rRNA processing/ribosome biogenesis Sec7_N PF12783.7 KFL62952.1 - 0.00027 20.9 0.3 0.0095 15.8 0.1 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3437 PF11919.8 KFL62952.1 - 0.00055 19.8 0.7 0.16 11.9 0.0 4.6 6 0 0 6 6 5 1 Domain of unknown function (DUF3437) Dopey_N PF04118.14 KFL62952.1 - 0.00057 19.1 0.2 0.052 12.6 0.0 2.7 3 0 0 3 3 3 1 Dopey, N-terminal Adaptin_N PF01602.20 KFL62952.1 - 0.00076 18.2 0.2 0.16 10.5 0.0 3.6 2 2 1 3 3 3 1 Adaptin N terminal region IBN_N PF03810.19 KFL62952.1 - 0.00095 19.0 0.7 0.17 11.8 0.0 4.3 3 2 1 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.23 KFL62952.1 - 0.00098 19.1 7.1 2 8.6 0.0 6.3 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KFL62952.1 - 0.0044 17.2 0.0 0.029 14.5 0.0 2.5 2 0 0 2 2 1 1 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 KFL62952.1 - 0.11 12.2 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 DNA alkylation repair enzyme HEAT_PBS PF03130.16 KFL62952.1 - 0.13 13.0 4.2 26 5.9 0.0 5.4 7 0 0 7 7 3 0 PBS lyase HEAT-like repeat Adap_comp_sub PF00928.21 KFL62953.1 - 5.6e-23 81.6 0.0 7.2e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Adap_comp_sub PF00928.21 KFL62954.1 - 4.1e-23 82.1 0.0 5.2e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Cyt-b5 PF00173.28 KFL62955.1 - 1.7e-18 66.5 0.1 1.7e-18 66.5 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Anth_synt_I_N PF04715.13 KFL62955.1 - 0.0056 16.9 0.2 0.012 15.8 0.2 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region ABC_tran PF00005.27 KFL62958.1 - 1.8e-05 25.3 0.0 4.7e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KFL62958.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KFL62958.1 - 0.088 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KFL62959.1 - 1.7e-06 28.6 0.0 2.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFL62959.1 - 3.7e-05 23.3 0.2 4.8e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFL62959.1 - 0.0029 17.5 0.1 0.0033 17.3 0.1 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF1345 PF07077.11 KFL62959.1 - 0.025 14.3 1.7 0.037 13.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) Methyltransf_16 PF10294.9 KFL62960.1 - 1.4e-22 80.3 0.0 1.9e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Ribosomal_S25 PF03297.15 KFL62961.1 - 2.7e-38 130.2 5.4 2.9e-38 130.1 5.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.12 KFL62961.1 - 0.0044 16.8 0.1 0.006 16.3 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 KFL62961.1 - 0.017 15.5 0.1 0.023 15.0 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_11 PF08279.12 KFL62961.1 - 0.022 14.7 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 KFL62961.1 - 0.04 13.5 0.1 0.062 12.9 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KFL62961.1 - 0.072 13.0 0.3 0.098 12.6 0.3 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 KFL62961.1 - 0.075 12.9 0.1 0.093 12.6 0.1 1.2 1 0 0 1 1 1 0 MarR family Ribosomal_S25 PF03297.15 KFL62962.1 - 1.1e-27 96.1 1.1 1.3e-27 95.9 1.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.12 KFL62962.1 - 0.0033 17.1 0.1 0.0044 16.7 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 KFL62962.1 - 0.013 15.8 0.1 0.017 15.4 0.1 1.3 1 1 0 1 1 1 0 Transcriptional regulator HTH_11 PF08279.12 KFL62962.1 - 0.016 15.2 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 KFL62962.1 - 0.035 13.7 0.1 0.045 13.3 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KFL62962.1 - 0.052 13.4 0.2 0.063 13.2 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 KFL62962.1 - 0.061 13.2 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 MarR family Ribosomal_S25 PF03297.15 KFL62963.1 - 3e-29 101.2 1.3 3.5e-29 101.0 1.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.12 KFL62963.1 - 0.0028 17.4 0.1 0.0037 17.0 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 KFL62963.1 - 0.011 16.0 0.1 0.015 15.7 0.1 1.3 1 1 0 1 1 1 0 Transcriptional regulator HTH_11 PF08279.12 KFL62963.1 - 0.015 15.3 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 KFL62963.1 - 0.029 13.9 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KFL62963.1 - 0.048 13.5 0.3 0.053 13.4 0.3 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 KFL62963.1 - 0.051 13.5 0.1 0.061 13.2 0.1 1.2 1 0 0 1 1 1 0 MarR family Gtr1_RagA PF04670.12 KFL62964.1 - 1.6e-56 191.3 0.6 1.9e-56 191.0 0.6 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFL62964.1 - 0.013 15.3 0.2 0.018 14.8 0.2 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Arf PF00025.21 KFL62964.1 - 0.026 14.0 0.1 0.045 13.2 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Imm74 PF15603.6 KFL62964.1 - 0.088 13.0 0.1 6 7.1 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 74 Gtr1_RagA PF04670.12 KFL62965.1 - 3.2e-51 173.9 0.8 3.8e-51 173.7 0.8 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFL62965.1 - 0.041 13.7 0.1 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Arf PF00025.21 KFL62965.1 - 0.057 12.9 0.1 0.096 12.1 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Imm74 PF15603.6 KFL62965.1 - 0.076 13.2 0.1 5.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 74 Methyltransf_3 PF01596.17 KFL62966.1 - 1e-08 34.6 0.0 2.1e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Serglycin PF04360.12 KFL62967.1 - 0.0062 16.5 4.2 0.0062 16.5 4.2 2.5 3 0 0 3 3 3 1 Serglycin Serglycin PF04360.12 KFL62968.1 - 0.0045 17.0 4.0 0.0045 17.0 4.0 2.6 3 0 0 3 3 3 1 Serglycin Peptidase_S64 PF08192.11 KFL62970.1 - 0.012 14.2 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 SR-25 PF10500.9 KFL62971.1 - 0.077 12.6 6.6 0.047 13.3 4.9 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2293 PF10056.9 KFL62973.1 - 2.2e-28 98.3 1.4 2.6e-28 98.1 0.4 1.6 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2293) DUF3754 PF12576.8 KFL62973.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) FYDLN_acid PF09538.10 KFL62973.1 - 0.15 12.7 1.0 0.2 12.3 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CPSF73-100_C PF11718.8 KFL62975.1 - 2.1e-79 266.1 0.0 2.8e-79 265.7 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B PF00753.27 KFL62976.1 - 0.002 18.2 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KFL62976.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Kdo PF06293.14 KFL62977.1 - 3e-07 30.0 0.2 6.6e-07 28.9 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.14 KFL62977.1 - 0.034 12.4 9.9 0.066 11.5 9.9 1.4 1 0 0 1 1 1 0 CDC45-like protein APH PF01636.23 KFL62977.1 - 0.036 14.0 0.1 0.036 14.0 0.1 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 KFL62977.1 - 0.071 12.5 0.3 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain MAP7 PF05672.11 KFL62977.1 - 0.13 11.9 42.7 0.32 10.7 42.7 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family AsmA PF05170.14 KFL62977.1 - 0.23 10.2 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 AsmA family CAF-1_p150 PF11600.8 KFL62977.1 - 0.32 10.7 31.2 0.62 9.7 31.2 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ARGLU PF15346.6 KFL62977.1 - 2.2 8.2 41.8 4.9 7.0 41.8 1.5 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF913 PF06025.12 KFL62977.1 - 4.1 6.3 5.5 8.5 5.2 5.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spore_coat_CotO PF14153.6 KFL62977.1 - 6.6 6.6 21.0 32 4.4 16.8 2.3 2 0 0 2 2 2 0 Spore coat protein CotO CiPC PF15800.5 KFL62977.1 - 8.8 5.9 21.0 6.7 6.3 4.5 3.1 3 0 0 3 3 3 0 Clock interacting protein circadian Peptidase_S41 PF03572.18 KFL62978.1 - 7.2e-08 32.2 0.0 2e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 DUF1659 PF07872.11 KFL62978.1 - 0.028 14.1 0.2 0.058 13.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) Transferase PF02458.15 KFL62979.1 - 1.5e-19 70.0 0.0 2.3e-12 46.3 0.0 2.1 2 0 0 2 2 2 2 Transferase family Transferase PF02458.15 KFL62980.1 - 1.5e-06 27.2 0.0 2.1e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 Transferase family Peptidase_S8 PF00082.22 KFL62981.1 - 2.5e-20 73.0 9.8 8.7e-20 71.2 9.8 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFL62981.1 - 1.9e-17 63.7 0.1 6.7e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase inhibitor I9 Inhibitor_I9 PF05922.16 KFL62982.1 - 1.5e-17 64.0 0.1 5.7e-17 62.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 KFL62982.1 - 4.8e-16 58.9 6.4 1.8e-15 57.0 6.4 1.7 1 1 0 1 1 1 1 Subtilase family Auts2 PF15336.6 KFL62983.1 - 0.065 13.3 0.0 0.094 12.8 0.0 1.1 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Fungal_trans PF04082.18 KFL62987.1 - 1e-15 57.5 0.1 1.7e-15 56.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain A_deaminase PF00962.22 KFL62988.1 - 0.06 12.7 0.0 0.066 12.5 0.0 1.0 1 0 0 1 1 1 0 Adenosine/AMP deaminase Peptidase_S10 PF00450.22 KFL62990.1 - 2e-130 436.0 0.1 2.3e-130 435.8 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KFL62990.1 - 6.1e-06 26.8 0.6 4.5e-05 24.0 0.6 2.3 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide FancD2 PF14631.6 KFL62992.1 - 0.96 6.8 8.5 1.5 6.2 8.5 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF4407 PF14362.6 KFL62992.1 - 2.5 7.4 5.5 4.7 6.5 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3043 PF11241.8 KFL62992.1 - 3.8 7.5 11.9 7.2 6.6 11.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Pyridoxal_deC PF00282.19 KFL62993.1 - 1.6e-78 264.0 0.0 2.1e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFL62993.1 - 2.7e-05 23.3 0.0 3.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KFL62993.1 - 0.03 13.1 0.0 0.045 12.5 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 KFL62993.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KFL62994.1 - 4.4e-75 252.7 0.0 5.2e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFL62994.1 - 1.9e-05 23.8 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KFL62994.1 - 0.024 13.4 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 KFL62994.1 - 0.041 13.2 0.2 0.082 12.2 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family WD40_like PF17005.5 KFL62995.1 - 1.6e-05 24.4 0.5 0.0012 18.3 0.1 2.8 3 0 0 3 3 3 2 WD40-like domain HPS3_N PF14761.6 KFL62995.1 - 0.00048 19.7 0.0 0.0056 16.2 0.0 2.7 4 0 0 4 4 4 1 Hermansky-Pudlak syndrome 3 Clathrin PF00637.20 KFL62996.1 - 1.1e-20 73.9 4.7 4.9e-18 65.4 1.0 2.8 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_11 PF13414.6 KFL62996.1 - 0.00039 20.0 0.9 0.0011 18.5 0.1 2.2 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 KFL62996.1 - 0.002 18.8 0.0 0.15 12.9 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFL62996.1 - 0.0042 17.2 0.6 0.62 10.4 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFL62996.1 - 0.019 15.2 1.0 0.63 10.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Med1 PF10744.9 KFL62996.1 - 0.057 12.4 0.1 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription subunit 1 TPR_2 PF07719.17 KFL62996.1 - 0.27 11.4 4.8 0.35 11.1 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFL62996.1 - 2.2 8.2 6.6 1.6 8.7 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFL62996.1 - 10 6.5 7.6 12 6.2 0.1 4.0 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 UAE_UbL PF14732.6 KFL62998.1 - 2.7e-22 79.1 0.1 4.8e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain ThiF PF00899.21 KFL62998.1 - 0.00025 20.5 0.1 0.00039 19.8 0.1 1.3 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KFL62998.1 - 0.023 14.8 0.2 0.082 13.1 0.1 2.0 2 0 0 2 2 2 0 E2 binding domain UAE_UbL PF14732.6 KFL62999.1 - 2.7e-22 79.1 0.1 4.8e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain ThiF PF00899.21 KFL62999.1 - 0.00025 20.5 0.1 0.00039 19.8 0.1 1.3 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KFL62999.1 - 0.023 14.8 0.2 0.082 13.1 0.1 2.0 2 0 0 2 2 2 0 E2 binding domain UAE_UbL PF14732.6 KFL63000.1 - 2.5e-22 79.3 0.1 3.8e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain ThiF PF00899.21 KFL63000.1 - 0.00023 20.6 0.1 0.00035 20.0 0.1 1.3 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KFL63000.1 - 0.023 14.9 0.2 0.08 13.1 0.1 1.9 2 0 0 2 2 2 0 E2 binding domain PcrB PF01884.17 KFL63000.1 - 0.038 13.4 0.3 0.97 8.8 0.0 2.3 1 1 1 2 2 2 0 PcrB family ThiF PF00899.21 KFL63001.1 - 3.4e-64 216.5 0.0 4e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 KFL63001.1 - 2.2e-05 24.8 0.0 4.3e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KFL63001.1 - 0.0063 16.6 0.0 0.0099 15.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KFL63001.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DNA_pol_delta_4 PF04081.13 KFL63002.1 - 1.5e-35 122.4 3.9 3.4e-35 121.2 3.9 1.7 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Asp PF00026.23 KFL63004.1 - 0.00044 19.8 0.0 0.00065 19.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 KFL63004.1 - 0.083 12.3 5.0 0.17 11.3 5.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Zn_clus PF00172.18 KFL63007.1 - 3.9e-06 26.9 10.2 6.2e-06 26.2 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 KFL63009.1 - 6.7e-98 328.2 0.0 7.6e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HNH_2 PF13391.6 KFL63010.1 - 4.2e-06 26.8 0.0 9.6e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease p450 PF00067.22 KFL63012.1 - 2e-39 135.7 0.0 1.4e-27 96.6 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KFL63013.1 - 4.1e-46 157.7 0.0 5.3e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFL63014.1 - 7.8e-25 87.5 0.0 8.6e-18 64.3 0.0 3.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 KFL63015.1 - 6.8e-23 81.1 0.0 1.1e-15 57.4 0.0 3.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 KFL63016.1 - 4.5e-08 32.3 0.0 0.0038 16.0 0.0 2.8 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 KFL63017.1 - 3.4e-08 32.7 0.0 0.0041 15.9 0.0 2.8 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 KFL63018.1 - 1.1e-21 77.2 0.0 1.6e-16 60.1 0.0 3.0 1 1 2 3 3 3 3 Cytochrome P450 p450 PF00067.22 KFL63019.1 - 7.9e-05 21.6 0.0 0.0026 16.6 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Fungal_trans PF04082.18 KFL63021.1 - 6e-22 78.0 2.7 1e-21 77.2 2.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S8e PF01201.22 KFL63022.1 - 2.5e-47 160.5 1.9 4e-47 159.8 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e RIBIOP_C PF04950.12 KFL63022.1 - 0.21 11.0 6.5 0.52 9.7 6.5 1.7 1 1 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Glyco_hydro_38N PF01074.22 KFL63024.1 - 1.6e-86 290.3 0.6 3e-86 289.4 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFL63024.1 - 2.3e-55 188.0 0.4 2.1e-54 184.8 0.2 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFL63024.1 - 6.2e-26 90.4 0.0 1.3e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KFL63024.1 - 4.1e-09 36.4 0.0 1.3e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Fucosidase_C PF16757.5 KFL63024.1 - 0.05 14.2 0.1 3 8.5 0.1 2.5 2 0 0 2 2 2 0 Alpha-L-fucosidase C-terminal domain 7TMR-DISMED2 PF07696.11 KFL63025.1 - 0.0042 17.1 0.0 0.0057 16.7 0.0 1.3 1 0 0 1 1 1 1 7TMR-DISM extracellular 2 DUF2838 PF10998.8 KFL63027.1 - 2.5e-39 133.9 11.0 2.5e-39 133.9 11.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Exonuc_VII_L PF02601.15 KFL63027.1 - 0.062 12.9 0.3 0.092 12.3 0.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ApoLp-III PF07464.11 KFL63027.1 - 0.064 13.3 2.4 0.11 12.5 2.4 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Tropomyosin_1 PF12718.7 KFL63027.1 - 0.068 13.3 2.2 0.13 12.4 2.2 1.3 1 0 0 1 1 1 0 Tropomyosin like OmpH PF03938.14 KFL63027.1 - 2.7 8.3 8.7 0.99 9.7 5.7 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SMC_N PF02463.19 KFL63028.1 - 2.2e-42 145.0 0.0 2.4e-37 128.5 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFL63028.1 - 2.3e-30 105.3 1.1 1.3e-29 102.9 0.0 2.9 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KFL63028.1 - 3.6e-06 27.0 1.9 3.6e-06 27.0 1.9 3.3 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system CALCOCO1 PF07888.11 KFL63028.1 - 0.00092 18.2 3.5 0.00092 18.2 3.5 5.2 3 2 1 5 5 5 3 Calcium binding and coiled-coil domain (CALCOCO1) like SbcCD_C PF13558.6 KFL63028.1 - 0.0028 17.8 0.0 0.03 14.6 0.0 2.8 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF4200 PF13863.6 KFL63028.1 - 0.0094 16.3 4.7 0.0094 16.3 4.7 9.0 5 4 4 9 9 9 4 Domain of unknown function (DUF4200) DUF1664 PF07889.12 KFL63028.1 - 0.56 10.3 61.8 1.1 9.3 5.2 9.0 5 3 4 10 10 10 0 Protein of unknown function (DUF1664) SMC_hinge PF06470.13 KFL63029.1 - 1.6e-30 105.8 0.6 1.1e-29 103.1 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain CALCOCO1 PF07888.11 KFL63029.1 - 0.00081 18.4 3.5 0.00081 18.4 3.5 5.2 3 2 1 5 5 5 3 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4200 PF13863.6 KFL63029.1 - 0.0068 16.8 4.4 0.0068 16.8 4.4 9.1 4 3 4 9 9 9 4 Domain of unknown function (DUF4200) SMC_N PF02463.19 KFL63029.1 - 0.021 14.2 0.0 0.021 14.2 0.0 2.9 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF1664 PF07889.12 KFL63029.1 - 0.65 10.0 63.5 1.1 9.3 5.3 9.1 5 3 5 11 11 11 0 Protein of unknown function (DUF1664) SMC_hinge PF06470.13 KFL63030.1 - 1.4e-30 106.0 0.6 1e-29 103.2 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain CALCOCO1 PF07888.11 KFL63030.1 - 0.00073 18.5 3.5 0.00073 18.5 3.5 4.2 2 2 1 4 4 4 2 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4200 PF13863.6 KFL63030.1 - 0.0048 17.3 4.1 0.0048 17.3 4.1 7.8 3 2 4 8 8 8 4 Domain of unknown function (DUF4200) SMC_N PF02463.19 KFL63030.1 - 0.02 14.4 0.0 0.02 14.4 0.0 3.0 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF1664 PF07889.12 KFL63030.1 - 2.7 8.0 55.9 1 9.4 5.4 7.7 4 2 4 9 9 9 0 Protein of unknown function (DUF1664) Sec20 PF03908.13 KFL63031.1 - 1.6e-15 56.8 2.4 1.6e-15 56.8 2.4 1.8 2 0 0 2 2 2 1 Sec20 CUT PF02376.15 KFL63031.1 - 0.44 10.7 3.3 2.2 8.5 3.3 2.1 1 1 0 1 1 1 0 CUT domain Plasmid_RAQPRD PF09686.10 KFL63031.1 - 9.5 6.5 8.6 0.5 10.6 0.3 2.7 2 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Peptidase_M28 PF04389.17 KFL63032.1 - 7.2e-44 149.9 0.5 1.2e-43 149.1 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KFL63032.1 - 1.9e-13 50.2 0.7 5e-13 48.9 0.7 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.14 KFL63032.1 - 0.0042 16.2 0.0 0.17 10.9 0.0 2.5 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 KFL63032.1 - 0.0077 15.9 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KFL63033.1 - 6e-44 150.1 0.1 7.8e-44 149.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFL63033.1 - 7e-12 45.2 0.1 2.1e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.14 KFL63033.1 - 0.004 16.2 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 KFL63033.1 - 0.0066 16.2 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KFL63033.1 - 0.2 11.1 0.1 0.74 9.2 0.0 1.9 2 0 0 2 2 2 0 Nicastrin SCNM1_acidic PF15805.5 KFL63034.1 - 0.12 12.1 1.4 0.38 10.5 1.4 1.8 1 1 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 JAB PF01398.21 KFL63036.1 - 4.9e-08 33.0 0.2 3.4e-06 27.0 0.2 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease JAB PF01398.21 KFL63037.1 - 1.7e-05 24.8 0.1 0.0011 18.9 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease JAB PF01398.21 KFL63038.1 - 1.7e-05 24.8 0.1 0.0011 18.9 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease JAB PF01398.21 KFL63039.1 - 0.00034 20.6 0.1 0.022 14.7 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HMG_box_2 PF09011.10 KFL63040.1 - 0.011 16.3 0.1 0.011 16.3 0.1 2.4 2 0 0 2 2 2 0 HMG-box domain zf-C2H2 PF00096.26 KFL63041.1 - 2.5e-12 46.5 8.4 7.8e-07 29.2 0.9 7.9 8 0 0 8 8 7 4 Zinc finger, C2H2 type zf-met PF12874.7 KFL63041.1 - 5.6e-10 39.3 8.6 0.00035 20.9 0.3 5.0 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFL63041.1 - 6.1e-10 39.1 10.2 5.6e-08 32.9 0.8 6.6 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFL63041.1 - 4.6e-09 36.3 7.1 0.0034 17.6 0.3 4.7 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFL63041.1 - 5.9e-08 32.9 7.3 0.00021 21.9 0.6 7.8 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFL63041.1 - 3.5e-07 30.1 12.0 0.00054 19.9 0.6 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFL63041.1 - 4.4e-06 26.4 1.4 0.094 12.5 0.1 3.7 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFL63041.1 - 3.9e-05 23.4 1.9 0.037 14.0 0.3 4.0 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFL63041.1 - 0.00027 20.4 1.9 4.2 7.1 0.1 3.9 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 KFL63041.1 - 0.28 11.2 17.3 1.4 9.0 1.2 5.0 3 1 2 5 5 5 0 BED zinc finger BolA PF01722.18 KFL63041.1 - 0.43 10.9 5.3 0.71 10.2 0.1 3.1 3 1 1 4 4 3 0 BolA-like protein zf-met PF12874.7 KFL63042.1 - 8.2e-10 38.8 2.7 0.00034 20.9 0.3 4.7 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KFL63042.1 - 3.5e-09 36.6 6.5 2.2e-06 27.8 0.4 7.0 7 0 0 7 7 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFL63042.1 - 5.4e-08 32.9 0.8 5.4e-08 32.9 0.8 5.7 6 0 0 6 6 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFL63042.1 - 3.3e-06 27.2 8.6 0.0033 17.7 0.3 4.5 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFL63042.1 - 4.8e-06 26.4 12.2 0.00052 19.9 0.6 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFL63042.1 - 6.6e-06 26.5 37.5 0.0002 21.9 0.6 6.9 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFL63042.1 - 3.1e-05 23.7 1.2 0.035 14.0 0.3 4.0 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFL63042.1 - 0.00046 19.9 1.4 0.091 12.5 0.1 3.7 3 0 0 3 3 3 1 zinc-finger C2H2-type zf_UBZ PF18439.1 KFL63042.1 - 0.00091 18.8 2.1 4 7.1 0.1 4.3 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 KFL63042.1 - 0.36 10.9 11.1 4 7.6 0.3 4.1 3 1 1 4 4 4 0 BED zinc finger Zn-ribbon_8 PF09723.10 KFL63042.1 - 1.6 8.9 10.7 0.3 11.3 0.5 3.4 3 0 0 3 3 3 0 Zinc ribbon domain Nup192 PF11894.8 KFL63045.1 - 0 1259.9 23.8 0 1259.6 23.8 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup192 PF11894.8 KFL63046.1 - 0 1273.1 23.0 0 1272.8 23.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup192 PF11894.8 KFL63047.1 - 0 1273.1 23.0 0 1272.9 23.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup192 PF11894.8 KFL63048.1 - 0 1198.2 20.6 0 1198.0 20.6 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup192 PF11894.8 KFL63049.1 - 0 1211.4 19.8 0 1211.2 19.8 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Cullin PF00888.22 KFL63050.1 - 1.5e-81 274.9 2.7 1.8e-81 274.6 2.7 1.0 1 0 0 1 1 1 1 Cullin family AhpC-TSA_2 PF13911.6 KFL63050.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Cullin PF00888.22 KFL63051.1 - 6.3e-59 200.1 0.0 9.4e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFL63051.1 - 1.5e-25 89.0 1.4 3.9e-25 87.7 1.4 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Rio2_N PF09202.11 KFL63051.1 - 0.051 13.8 0.3 9.8 6.5 0.1 2.5 2 0 0 2 2 2 0 Rio2, N-terminal Dak1 PF02733.17 KFL63052.1 - 4.2e-106 354.4 2.0 5.5e-106 354.0 2.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KFL63052.1 - 5e-48 163.3 0.4 2.3e-47 161.1 0.3 2.0 2 0 0 2 2 2 1 DAK2 domain DUF2497 PF10691.9 KFL63052.1 - 0.091 13.2 0.2 0.35 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Dak2 PF02734.17 KFL63053.1 - 6.6e-48 162.9 0.3 1.2e-47 162.1 0.3 1.4 1 0 0 1 1 1 1 DAK2 domain Dak1 PF02733.17 KFL63053.1 - 1.4e-40 139.2 0.1 2.1e-40 138.6 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain DUF2497 PF10691.9 KFL63053.1 - 0.053 14.0 0.2 0.24 11.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) LSM PF01423.22 KFL63054.1 - 6e-19 67.5 0.1 8.4e-19 67.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain CAV_VP3 PF04771.12 KFL63054.1 - 0.17 12.0 0.0 12 6.1 0.0 2.0 1 1 1 2 2 2 0 Chicken anaemia virus VP-3 protein NAD_kinase PF01513.21 KFL63057.1 - 4.1e-68 229.7 0.0 5.6e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase NAD_kinase PF01513.21 KFL63058.1 - 4.1e-68 229.7 0.0 5.6e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase NAD_kinase PF01513.21 KFL63059.1 - 2.2e-34 119.0 0.0 3.1e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase NAD_kinase PF01513.21 KFL63060.1 - 2.2e-34 119.0 0.0 3.1e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase ECH_2 PF16113.5 KFL63061.1 - 1.3e-130 435.8 0.0 1.6e-130 435.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KFL63061.1 - 1.6e-27 96.4 0.0 1.2e-26 93.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase FHA PF00498.26 KFL63062.1 - 2.1e-14 53.6 0.0 3.9e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KFL63062.1 - 2.1e-10 40.2 4.2 4.1e-10 39.2 4.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KFL63062.1 - 6.6e-07 29.6 8.8 1.2e-06 28.7 8.8 1.5 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 KFL63062.1 - 0.00028 21.2 0.0 0.00061 20.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 KFL63062.1 - 0.001 19.0 6.7 0.002 18.0 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFL63062.1 - 0.0095 15.8 8.1 0.018 14.9 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFL63062.1 - 0.015 15.2 8.7 0.028 14.3 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KFL63062.1 - 0.016 15.5 5.5 0.037 14.3 5.5 1.7 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 KFL63062.1 - 0.039 14.0 2.9 0.081 13.0 2.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFL63062.1 - 0.11 12.9 8.2 0.34 11.2 8.2 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 KFL63062.1 - 0.15 11.9 5.6 0.33 10.9 5.6 1.6 1 0 0 1 1 1 0 PHD-finger TFIIA PF03153.13 KFL63062.1 - 0.31 11.0 23.0 0.043 13.8 13.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_4 PF15227.6 KFL63062.1 - 2.5 8.3 6.8 4.9 7.4 6.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KFL63062.1 - 3 7.5 8.1 6.3 6.5 8.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Arm PF00514.23 KFL63063.1 - 2.5e-56 186.1 18.8 2e-11 43.5 0.1 8.3 7 1 1 8 8 8 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFL63063.1 - 1.2e-12 48.0 5.2 7.7e-05 23.0 0.0 4.9 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 KFL63063.1 - 1.8e-11 44.3 13.6 0.0057 17.1 0.1 6.6 5 2 2 7 7 7 3 HEAT-like repeat HEAT PF02985.22 KFL63063.1 - 3.2e-11 42.5 10.7 0.14 12.5 0.2 6.8 7 0 0 7 7 7 3 HEAT repeat Adaptin_N PF01602.20 KFL63063.1 - 2e-09 36.5 5.4 8.3e-05 21.3 3.5 2.7 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 KFL63063.1 - 7.7e-09 34.3 0.5 1e-08 33.8 0.5 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 KFL63063.1 - 2e-06 27.5 5.1 0.022 14.2 0.1 2.5 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 KFL63063.1 - 8.2e-06 25.3 0.8 0.00022 20.6 0.6 2.5 1 1 1 2 2 2 2 V-ATPase subunit H DUF5578 PF17741.1 KFL63063.1 - 0.00053 19.5 7.0 0.079 12.4 0.1 3.7 1 1 3 4 4 4 1 Family of unknown function (DUF5578) V-ATPase_H_C PF11698.8 KFL63063.1 - 0.00087 19.4 2.2 18 5.4 0.0 4.5 1 1 4 5 5 5 0 V-ATPase subunit H PUL PF08324.11 KFL63063.1 - 0.0024 17.2 4.0 0.0052 16.1 1.1 2.4 1 1 1 2 2 2 1 PUL domain UNC45-central PF11701.8 KFL63063.1 - 0.0033 17.4 1.7 0.66 9.9 0.1 3.0 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT_PBS PF03130.16 KFL63063.1 - 0.013 16.1 4.5 0.71 10.7 0.5 4.3 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFL63063.1 - 0.068 13.8 0.0 0.33 11.6 0.1 2.2 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.9 KFL63063.1 - 0.094 12.7 8.8 1.1 9.3 0.2 4.6 3 3 2 5 5 5 0 Spinocerebellar ataxia type 10 protein domain YqfD PF06898.11 KFL63063.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD GTP_EFTU_D2 PF03144.25 KFL63064.1 - 4.2e-08 33.5 0.0 1.1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFL63064.1 - 1.9e-07 31.1 0.0 4.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Prp19 PF08606.11 KFL63065.1 - 2.6e-33 113.8 1.2 5.1e-33 112.9 1.2 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like V_ATPase_I_N PF18670.1 KFL63065.1 - 0.00031 21.1 0.2 0.00071 19.9 0.2 1.6 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain Rtf2 PF04641.12 KFL63065.1 - 0.0045 16.4 0.0 0.0073 15.7 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KFL63065.1 - 0.036 13.9 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit WD40_like PF17005.5 KFL63065.1 - 0.1 11.9 0.1 0.58 9.4 0.0 1.9 1 1 1 2 2 2 0 WD40-like domain Dynamin_N PF00350.23 KFL63067.1 - 3e-18 66.5 0.9 2.9e-17 63.2 0.1 2.8 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KFL63067.1 - 1.9e-10 40.8 0.0 1.1e-08 35.2 0.0 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFL63067.1 - 1.1e-07 31.6 0.0 7.2e-05 22.4 0.1 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF2205 PF10224.9 KFL63067.1 - 0.025 14.6 0.1 0.091 12.8 0.1 1.9 1 0 0 1 1 1 0 Short coiled-coil protein FeoB_N PF02421.18 KFL63067.1 - 0.09 12.3 0.2 39 3.7 0.0 3.7 4 0 0 4 4 4 0 Ferrous iron transport protein B AAA_18 PF13238.6 KFL63067.1 - 0.093 13.3 0.1 0.58 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KFL63067.1 - 0.098 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KFL63067.1 - 0.1 12.8 0.1 3 8.1 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFL63067.1 - 0.15 11.8 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zn_clus PF00172.18 KFL63071.1 - 3.3e-07 30.3 14.8 5.8e-07 29.5 14.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_polI_A34 PF08208.11 KFL63071.1 - 0.38 10.8 4.3 0.68 10.0 4.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3484 PF11983.8 KFL63071.1 - 9.6 7.4 8.5 25 6.1 8.5 1.7 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch APH PF01636.23 KFL63073.1 - 1.5e-06 28.4 0.0 1.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KFL63073.1 - 0.01 14.7 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) FAS_I_H PF18314.1 KFL63076.1 - 2.3e-23 82.9 0.2 1.6e-22 80.1 0.0 2.2 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 KFL63076.1 - 4.4e-21 75.6 0.0 8.1e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KFL63076.1 - 8.9e-19 67.7 0.1 2.1e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KFL63076.1 - 2e-12 47.2 0.0 5.1e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KFL63076.1 - 6.6e-05 22.5 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFL63076.1 - 0.0025 17.8 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KFL63076.1 - 0.0027 17.3 0.0 0.006 16.2 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AAA_6 PF12774.7 KFL63076.1 - 0.14 11.1 0.0 0.42 9.5 0.0 1.8 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Fas_alpha_ACP PF18325.1 KFL63077.1 - 5.1e-76 254.5 0.0 7.3e-76 254.0 0.0 1.2 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 KFL63077.1 - 7.7e-11 42.0 2.0 1.2e-10 41.4 1.1 1.8 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain His_Phos_2 PF00328.22 KFL63078.1 - 1e-106 357.6 0.0 1.3e-106 357.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KFL63078.1 - 9.6e-38 128.2 0.0 2e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KFL63078.1 - 0.00011 21.8 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain PPIP5K2_N PF18086.1 KFL63079.1 - 6.9e-38 128.7 0.0 1.3e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain His_Phos_2 PF00328.22 KFL63079.1 - 1.3e-32 113.6 0.0 1.9e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.11 KFL63079.1 - 7.5e-05 22.4 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain WD40 PF00400.32 KFL63080.1 - 0.00017 22.3 17.3 3.8 8.5 0.1 8.6 10 1 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL63080.1 - 0.00092 19.5 0.0 28 5.1 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HeH PF12949.7 KFL63080.1 - 4.4 7.1 4.5 0.57 9.9 0.2 1.8 2 0 0 2 2 2 0 HeH/LEM domain Utp21 PF04192.12 KFL63081.1 - 4.8e-83 278.2 0.1 6.3e-83 277.8 0.1 1.1 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KFL63081.1 - 1.7e-08 35.0 6.9 3.9e-05 24.3 0.5 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFL63081.1 - 4e-06 27.0 0.1 0.00023 21.4 0.0 3.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFL63081.1 - 0.036 12.7 0.0 0.049 12.3 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF383 PF04063.14 KFL63082.1 - 1.7e-65 220.3 0.0 4.9e-65 218.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KFL63082.1 - 1.1e-21 76.4 1.1 1.1e-21 76.4 1.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Peptidase_C50 PF03568.17 KFL63082.1 - 0.00044 19.5 0.0 0.0007 18.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase family C50 SPO22 PF08631.10 KFL63082.1 - 0.056 12.9 0.1 0.089 12.3 0.1 1.3 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like ArgJ PF01960.18 KFL63082.1 - 0.099 11.4 0.2 0.15 10.8 0.2 1.2 1 0 0 1 1 1 0 ArgJ family FA_hydroxylase PF04116.13 KFL63085.1 - 7.8e-26 91.0 17.1 7.8e-26 91.0 17.1 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.13 KFL63086.1 - 2.1e-26 92.8 17.1 2.5e-26 92.6 17.1 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.13 KFL63087.1 - 2.1e-26 92.8 17.1 2.5e-26 92.6 17.1 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.13 KFL63088.1 - 2.1e-26 92.8 17.1 2.5e-26 92.6 17.1 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily PI3_PI4_kinase PF00454.27 KFL63089.1 - 9.6e-46 156.6 0.0 1.2e-45 156.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KFL63089.1 - 1.8e-14 53.3 0.0 3.4e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 FATC domain UME PF08064.13 KFL63090.1 - 0.011 15.6 0.4 0.051 13.5 0.1 2.3 2 0 0 2 2 2 0 UME (NUC010) domain DUF3385 PF11865.8 KFL63090.1 - 0.04 13.8 0.1 0.41 10.5 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) 3-alpha PF03475.14 KFL63090.1 - 0.12 12.3 0.1 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 3-alpha domain Fungal_trans PF04082.18 KFL63092.1 - 4.1e-07 29.3 0.0 5.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.29 KFL63094.1 - 1.1e-43 148.8 0.0 1.7e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFL63094.1 - 3.1e-14 52.5 0.0 7.6e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KFL63094.1 - 6.6e-08 32.9 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFL63094.1 - 1e-07 32.0 0.0 2.5e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFL63094.1 - 9.7e-07 29.3 0.0 7.8e-05 23.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFL63094.1 - 1.6e-05 25.2 0.2 0.008 16.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KFL63094.1 - 4.2e-05 23.3 0.0 8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFL63094.1 - 0.00064 20.3 0.1 0.012 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KFL63094.1 - 0.00075 18.8 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KFL63094.1 - 0.0012 19.0 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFL63094.1 - 0.0022 17.8 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KFL63094.1 - 0.0025 17.7 0.0 0.0076 16.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KFL63094.1 - 0.0065 15.9 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KFL63094.1 - 0.0067 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 KFL63094.1 - 0.0076 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KFL63094.1 - 0.0093 16.2 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFL63094.1 - 0.015 14.5 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KFL63094.1 - 0.015 15.0 0.0 0.072 12.8 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 KFL63094.1 - 0.021 14.3 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KFL63094.1 - 0.026 14.0 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 KFL63094.1 - 0.027 14.5 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFL63094.1 - 0.028 14.8 0.0 0.048 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KFL63094.1 - 0.028 14.1 0.0 0.078 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KFL63094.1 - 0.05 12.7 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KFL63094.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFL63094.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 KFL63094.1 - 0.17 12.2 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFL63094.1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFL63095.1 - 1.2e-43 148.7 0.0 1.7e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KFL63095.1 - 6.6e-08 32.9 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFL63095.1 - 9.9e-08 32.1 0.0 2.4e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFL63095.1 - 6.2e-06 26.7 0.1 7.8e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 KFL63095.1 - 7.2e-06 25.9 2.1 2.1e-05 24.4 2.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KFL63095.1 - 1.6e-05 25.2 0.2 0.0079 16.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KFL63095.1 - 4.1e-05 23.4 0.0 7.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFL63095.1 - 0.00074 18.8 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KFL63095.1 - 0.0011 19.1 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFL63095.1 - 0.0022 17.7 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KFL63095.1 - 0.004 17.0 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFL63095.1 - 0.0053 17.3 0.0 0.012 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFL63095.1 - 0.0054 16.1 0.0 0.014 14.7 0.0 1.7 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 KFL63095.1 - 0.0059 16.0 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KFL63095.1 - 0.0076 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KFL63095.1 - 0.0091 16.2 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KFL63095.1 - 0.014 15.1 0.0 0.071 12.8 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.13 KFL63095.1 - 0.015 14.5 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KFL63095.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KFL63095.1 - 0.023 14.1 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 KFL63095.1 - 0.026 14.9 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KFL63095.1 - 0.027 14.5 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain HR1 PF02185.16 KFL63095.1 - 0.027 14.6 0.7 0.07 13.3 0.7 1.7 1 0 0 1 1 1 0 Hr1 repeat AAA_24 PF13479.6 KFL63095.1 - 0.035 13.8 0.0 0.077 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFL63095.1 - 0.039 13.5 0.1 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KFL63095.1 - 0.05 12.7 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KFL63095.1 - 0.089 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 KFL63095.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 KFL63095.1 - 0.13 11.9 0.1 0.45 10.2 0.1 1.9 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain DUF2072 PF09845.9 KFL63095.1 - 0.17 12.1 0.1 0.29 11.4 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_11 PF13086.6 KFL63095.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFL63095.1 - 0.17 12.2 0.1 0.43 10.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFL63095.1 - 0.18 11.7 0.0 0.52 10.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DUF1688 PF07958.11 KFL63101.1 - 1.8e-45 155.4 0.0 4e-45 154.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) DUF1688 PF07958.11 KFL63102.1 - 1.8e-106 356.4 0.0 2.4e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF3431 PF11913.8 KFL63104.1 - 2.2e-78 262.9 3.6 5.3e-78 261.7 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) XPC-binding PF09280.11 KFL63104.1 - 5.2e-24 83.7 17.2 5.2e-24 83.7 17.2 2.0 2 0 0 2 2 2 1 XPC-binding domain UBA PF00627.31 KFL63104.1 - 2e-21 75.5 1.9 4.1e-12 45.7 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KFL63104.1 - 6.6e-17 61.0 0.0 1.2e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFL63104.1 - 5.4e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KFL63104.1 - 0.021 14.6 0.0 4.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF3391 PF11871.8 KFL63104.1 - 0.03 14.9 6.3 0.18 12.4 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Rad60-SLD_2 PF13881.6 KFL63104.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KFL63104.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Glyco_transf_22 PF03901.17 KFL63105.1 - 3.3e-24 85.9 3.0 4e-24 85.6 3.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Skp1 PF01466.19 KFL63106.1 - 3e-28 97.7 0.5 4.8e-28 97.0 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KFL63106.1 - 1.7e-24 85.7 0.2 4.1e-24 84.5 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DFF-C PF09033.10 KFL63106.1 - 0.044 13.7 0.1 0.08 12.8 0.0 1.5 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain Skp1_POZ PF03931.15 KFL63107.1 - 1.4e-24 86.1 0.1 2.1e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DIT1_PvcA PF05141.12 KFL63109.1 - 1.4e-92 310.1 0.0 1.8e-92 309.7 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.28 KFL63109.1 - 3.8e-23 81.8 0.0 6.1e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KFL63110.1 - 1.1e-08 35.3 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Transferase PF02458.15 KFL63110.1 - 1.2e-07 30.7 0.0 0.0046 15.7 0.0 2.1 2 0 0 2 2 2 2 Transferase family AMP-binding PF00501.28 KFL63111.1 - 7.7e-28 97.2 0.0 8.7e-28 97.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme T2SSG PF08334.11 KFL63111.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Condensation PF00668.20 KFL63112.1 - 2.7e-90 303.3 0.0 7e-45 153.5 0.0 2.1 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 KFL63112.1 - 6.2e-76 255.7 1.0 5.6e-69 232.8 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 KFL63112.1 - 1.3e-18 67.1 0.0 8.3e-10 38.9 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFL63112.1 - 0.00072 20.5 0.4 0.0037 18.2 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KFL63112.1 - 0.057 12.1 0.1 0.14 10.7 0.0 1.7 2 0 0 2 2 2 0 Transferase family Tugs PF17840.1 KFL63112.1 - 0.19 12.0 0.9 0.41 10.9 0.1 2.0 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain MFS_1 PF07690.16 KFL63113.1 - 1.5e-15 57.0 19.4 2e-15 56.6 19.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FPN1 PF06963.12 KFL63113.1 - 0.29 9.7 6.3 0.34 9.4 3.4 2.0 1 1 1 2 2 2 0 Ferroportin1 (FPN1) Phage_holin_5_2 PF16079.5 KFL63113.1 - 2 8.8 7.6 8.8 6.7 2.9 2.7 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V MFS_1 PF07690.16 KFL63114.1 - 0.69 8.8 12.2 5.9 5.7 1.0 1.8 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF2627 PF11118.8 KFL63114.1 - 6.9 7.3 9.1 1.2 9.7 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2627) p450 PF00067.22 KFL63115.1 - 7.4e-08 31.6 0.0 8.9e-08 31.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFL63116.1 - 1.3e-18 67.1 0.0 1.4e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Trichophyton_rubrum_CBS118892-ASM15142v1/GCA_000151425.1_ASM15142v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Trichophyton_rubrum_CBS118892-ASM15142v1/GCA_000151425.1_ASM15142v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Trichophyton_rubrum_CBS118892-ASM15142v1/GCA_000151425.1_ASM15142v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Trichophyton_rubrum_CBS118892-ASM15142v1/GCA_000151425.1_ASM15142v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 07:50:28 2019 # [ok]